Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
HyperDry Fusion – The First Hybrid Dryer Using Radio Frequency and Heat Pump for Net-Zero, Sustainable and Efficient Industrial Drying of Aggregates and Sludges. (HyperDry Fusion)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Industrial drying is one of industry’s last fossil frontiers — a hidden carbon and cost sink responsible for millions of tons of CO2 every year. In Europe alone, over 70 Mt of sand and aggregates are still dried with gas-fired drums, wasting half of their energy in hot exhausts and preventing circular reuse of wet recycled materials. Inventustry, a deep-tech startup from Reims born out of Personal Factory’s industrial ecosystem, has developed HyperDry Fusion: the world’s first full-electric hybrid dryer combining radio-frequency dielectric heating with a high-efficiency heat pump in a closed-loop air circuit. By heating water molecules directly — not the air or metal — HyperDry cuts energy use by ~50 % and CO2 by up to 95 % on renewable grids. No combustion, no dust, no stack — just clean, circular process heat ready for the net-zero era. Beyond construction, this scalable platform electrifies process heat < 250 °C — a €7.8 B global market — with applications from recycled aggregates to sludge, asphalt, food, and seed drying. HyperDry transforms static equipment into a dynamic energy node — a “Process-as-a-Battery” — capable of following renewable generation peaks and stabilizing industrial energy demand. Off-grid, it achieves OPEX € 5–6 /t, outperforming gas and even grid-scale storage in flexibility and efficiency. Validated at TRL5 (80 kW pilot) and now scaling to TRL9 (20 t/h demo), the project leverages a 22-member team with 330 years of cumulative expertise and the industrial capacity of Personal Factory for CE-certified production. EIC support (€ 2.5 M grant + € 10 M equity) will fast-track industrialization, securing EU leadership in electrified process heat — a massive, untapped decarbonization frontier representing >10 % of global industrial emissions.

Keywords: circular economy,drymix,radio frequency,rf,co2 reduction,demolition waste recycling,drying,green building,alkubo,localized production,logistics efficiency,
3rdAI Playlist Generator (3rdAI)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Ireland
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-03-01
End date: 2026-08-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

3rdAI is the world’s first research-grade Playlist Generator—a tool that combines the granular detail of user-defined searches across our specialist-curated, semantically-tagged 450,000+ track lyrical corpus with the machine learning features of our hip hop-savvy AI. Over the course of our cultural data analytics research on the ERC project, CIPHER: Hip Hop Interpellation (globalcipher.org), we identified that with the development of our 3rdAI Research Engine we had laid the groundwork for a commercializable and sustainable, AI-assisted Playlist Generator tool, profits from which could fund CIPHER’s global hip hop research, community engagement projects, and landmark OA scholarly publications—like the CIPHER journal, Global Hip Hop Studies—in perpetuity. Scaffolded atop our powerful Research Engine, the 3rdAI Playlist Generator will create synergies between our intended research applications and the massive market for streaming music discovery via bespoke sentiment analysis and recommender systems tools. The 3rdAI Playlist Generator thus revolutionizes the streaming and playlisting industries, bringing our next-level analysis of the archetypes and intertexts of this—the world’s most popular music—to the public. As outlined in our business plan, with 3rdAI, you can now search for—and visualize over time and space—hip hop’s multilingual, deeply intertextual references to war, peace, crime, community, migration, home, and any verbatim or thematically-related concepts you want to explore. But more than that, with the AI-assisted features of the 3rdAI Playlist Generator, now you can sonify your searches, uncovering and exploring the evolution of lyrics, beats, and themes through playlists that take you on a tour of hip hop history from Straight Outta Compton (Los Angeles, 1988) to Gully Boy (Mumbai, 2019) and beyond. Indeed, the name 3rdAI plays on a “gem” of hip hop knowledge, the “3rd eye” of hip hop consciousness—the oft-referenced archetype of hip hop insight.

Keywords: hip hop,mapping,music,data analytics,recommender systems,playlisting
Simultaneous Wireless Information and Power Transfer for Periauricular EMG Sensing (SWIPT-PEMG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-11-03
End date: 2027-11-02
Duration (months): 24.0
Total project cost (EUR): 268568.64
EU funding (EUR): 268568.64
Participants: 1
Project status: SIGNED

The over 1 million individuals worldwide with significant functional impairment due to spinal cord injury, Amyotrophic lateral sclerosis (ALS), or Locked-in Syndrome face hardships in interacting with a world constructed for those with functioning musculature innervation. The higher the injury to the spine, via contusion or disease progress, the greater the disconnect from the normative way of operating in the world. Assistive devices that respond to the musculature innervated by the cranial, and more specifically the facial, nerves can ease the burden on these individuals by giving them an additional vector by which to affect the world around them. The cranial nerves include those that humans do not commonly use to express on the modern world. These vestigial nerves provided function to ancestors, but now serve little purpose. One such vestigial musculature innervation are the periauricular muscles which oriented the ear in phylogenetically lower species. Even more significant though, functional innervation of these periauricular muscles remain even after the highest spinal cord injury. By sensing the electromyography (EMG) signal resulting from these vestigial periauricular muscles and relaying that signal to an external controller via a wirelessly powered implanted EMG sensing and backscatter communication device, one can provide exactly this revolutionary additional control vector without sacrificing a single otherwise commonly accessible facial motor control unit. The proposed SWIPT-PEMG will be minimally invasive, of miniscule size, be battery free, can transmit at data rates up to 2Mbps, is extremely low cost, and is predicted to improve SNR by 25 to 40% over existing wearable systems, thus we will provide control without cumbersome electronics of EEG, without the invasive and perilous surgeries of ECOG, and without the massive power demands of both.

Keywords: wireless,implantable,emg,backscatter,wpt,swipt,neuroengineering
Investigating neuro-immune crosstalk during enteric parasitic infections using human intestinal organoids (GUT INSTINCT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-06-01
End date: 2026-05-31
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

The gastrointestinal (GI) tract has its own nervous system, known as the enteric nervous system (ENS), which contains a network of enteric neurons and glial cells and controls GI physiology and functions. Studies have shown inflammatory responses as a result of enteric infections can cause damage or injury to the ENS and an imbalance in the ENS can cause GI disorders. The fine modulation of the inflammatory responses induced by components of the innate immune system (e.g. macrophages) along with other key players of the immune system is essential to generate an adequate response to fight infections, while preventing overactivation which can cause irreparable GI pathology leading to enteric diseases. The ENS is capable of performing this immunomodulatory role and share a common language with the immune system to provide adequate protection from infections and maintain GI physiology. However, little is known about how the “crosstalk” between the two systems keep enteric infections at bay. In this study, I propose to investigate how the neuro-immune crosstalk regulate GI physiology during enteric infections of T. trichiura and T. cruzi from a human host perspective. To do this, I will use human intestinal organoids (HIOs). The use of HIOs in the field of infection biology holds great promise and offers tremendous potential to establish one unified system containing immune cells and the ENS. In this project, I will create an integrated HIO system containing the ENS and components of the innate immune system to investigate the neuro-immune crosstalk of enteric parasites using 3D cell culture, live imaging, immunofluorescence and advanced transcriptomic and protein profiling. This will in turn open up new avenues to study the infection biology of other pathogens, establish targeted therapies and develop personalised medicine.

Keywords: neuroscience,immunology,ens,immune system,macrophages,enteric glial cells,enteric neurons,intestinal organoids,t cruzi,t trichiura
Clinopyroxene As a Quantitative Window Into Pre-Eruptive Magma Storage Conditions (CANVAS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-04-01
End date: 2028-03-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

The pre-eruptive pressure (depth) of magma storage beneath a volcano modulates the eruptive behaviour observed at the surface. Pressure controls the physical properties of magma such as the crystallinity via pressure-sensitive phase equilibria as well as the concentration of dissolved volatiles within the melt. Such parameters drastically affect how violently the volcano will erupt, and by extension the resultant societal and economic impact. However, it is increasingly apparent that one of the main ways that we recover pre-eruptive pressure from magmas, namely the link between the major element chemistry of the magmatic mineral clinopyroxene and pressure, is subject to large uncertainty. CANVAS will improve our understanding of the coupling between the chemical-structural variability of clinopyroxene and the crystallisation pressure. We will run a series of equilibrium crystallisation experiments on an Icelandic basalt starting material at atmospheric (1 atmosphere) and crustal (200 – 800 megapascals) pressures, employing thermal methods to grow large (>30 µm) crystals. Experimental clinopyroxenes will be measured for major elements using electron probe microanalyser. The same crystals will be subject to synchrotron X-ray microdiffraction to establish crystal structure and electron density, refining the “true” (observed) distribution of cations within the crystal lattice. The “true” composition of natural clinopyroxene has been previously shown to differ from assumed chemistry. In doing so, we will perform the first large, systematic study of clinopyroxene at crustal pressures by synchrotron to our knowledge. This approach will allow us to robustly isolate experimental pressure effects from temperature and melt composition, refining the observable chemical and physical response of clinopyroxene. Our findings will significantly improve the robustness of pressure estimates from erupted magmas, a key data source to benchmark geophysical signals in active volcanoes.

Keywords: petrological monitoring of volcanoes,experimental petrology,mineral chemistry
Telacebec to Control Buruli Ulcer and Leprosy in Africa (TEBULA) (TEBULA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Global Health EDCTP3
Action type: Research and Innovation actions
Partnership: EDCTP3 (JU-JTI)
Countries involved: France,Belgium,United Kingdom,Côte d'Ivoire,Ethiopia,United States,Benin,Spain,Ghana,Cameroon
Call: Accelerating development and integration of therapeutics against Neglected Tropical Diseases (NTDs) in sub-Saharan Africa (HORIZON-JU-GH-EDCTP3-2024-01-two-stage, 2024)
Start date: 2025-06-01
End date: 2029-05-31
Duration (months): 48.0
Total project cost (EUR): 6069390.0
EU funding (EUR): 5768415.0
Participants: 15
Project status: SIGNED

Leprosy (Hansen disease) and Buruli ulcer are among the devastating skin neglected tropical diseases (Skin NTDs) prevalent in sub-Saharan Africa that cause progressive and permanent disabilities, exposing the patients and their families to discrimination, social stigma, and economic burden, adding complex challenges to communities already exposed to extreme inequality. Considering the needs of the most affected populations, children and people living in rural remote areas, current treatments are suboptimal in their complexity and length. Treating leprosy requires multiple drugs administered for 6 to 12 months. Buruli ulcer treatment requires 3 pills daily at different hours for two months, and lesion healing can take up to 12 months. Both treatments are associated with significant side effects (skin discoloration from clofazimine, exacerbating the stigma that leprosy patients face, and potentially fatal hypersensitivity to dapsone). This proposal aims to transform the treatment of Buruli ulcer and leprosy using the novel compound telacebec. Telacebec has demonstrated profound activity against Mycobacterium ulcerans and Mycobacterium leprae, the causative agents of Buruli ulcer and leprosy, respectively, whose evolutionary biology has rendered them hypersusceptible to killing by telacebec. We propose to conduct two clinical trials with telacebec-based treatment regimens that will cure Buruli ulcer and leprosy with fewer drugs, shorter duration, and fewer side effects than current therapy. We will perform this work through an integrated, multidisciplinary consortium of experts with broad experience in drug development, therapeutic delivery, community engagement, stakeholder participation, policy implementation, and capacity building to achieve equitable access to a new standard of care for these diseases.

Keywords: leprosy buruli ulcer
Acorns revaluation for human consumption: genomic selection and development of new functional foods (ACOFOOD)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Greece,Spain
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-02, 2022)
Start date: 2022-11-01
End date: 2025-06-30
Duration (months): 32.0
Total project cost (EUR): 191858.4
EU funding (EUR): 191858.4
Participants: 4
Project status: CLOSED

The objective of ACOFOOD is to promote the consumption of acorn by human beings as it is a nutritious fruit with high production in the Mediterranean region, selecting the genotypes with the best functional characteristics for the consumer, identifying markers related to healthy phenolic compounds and , the absence of astringency and cytotoxicity, and developing a healthy acorn-based food. Dr. María Vázquez is a researcher with a scientific background in the field of postharvest of fruits and biomedicine, with great motivation to be able to combine these two disciplines, contributing to the implementation of a healthy and sustainable diet.

Keywords: acorn,quercus ilex,super food,astringency and cytotoxicity removal,functional compounds,mediterranean diet
Plasticity of nuclear cycling in response to the environment (PCNE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: SIGNED

The traditional view of proliferation in eukaryotic cells maintains that genome duplication is followed by cellular division into two new daughter cells, each containing its own nucleus. Organisms have evolved diverse strategies to accomplish this feat efficiently whilst acted upon by different selection pressures, some of which alter the mode of proliferation altogether. Strikingly, several organisms across the tree of life have evolved to utilize the multiplication of genetic material without the generation of new daughter cells as a successful replicative strategy. Although the nuclei reside in a shared cytoplasm, the dynamics of the nuclear cycles of multinucleate cells vary across organisms, from synchronicity, such as in the Drosophila embryo, to asynchronous replication as in the filamentous fungi Ashbya gossypii. While the fast, synchronized divisions in developing Drosophila embryos are hypothesized to benefit growth speeds, asynchronous divisions are hypothesized to balance replication speed with resource availability. While it is evident that the efficient use of resources for regulating the cell cycle control network is fundamental for survival and adaptation to the environment, the factors and molecular mechanisms regulating autonomous nuclear cycles in multinucleate cells are largely unknown. Using a combination of multiplexed spatial transcriptomics, classic cell biology approaches, high-resolution imaging, and molecular genetics, the proposed project will elucidate the extent to which the environment influences nuclear cycling in two evolutionarily distant eukaryotes, the free-living slime mold, Physarum polycephalum and the intracellular parasite, Plasmodium falciparum.

Keywords: protist apicomplexa evolutionary cell biology physarum polycephalum multinucleate cell division mitosis
Virtual Environment and Tool-boxing for Trustworthy Development of RISC-V based Cloud Services (Vitamin-V)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Greece,France,Sweden
Call: Open source for cloud-based services (RIA) (HORIZON-CL4-2022-DIGITAL-EMERGING-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 4635818.75
EU funding (EUR): 4635818.75
Participants: 10
Project status: SIGNED

Vitamin-V aims to develop a complete RISC-V open-source software stack for cloud services with iso-performance to the cloud-dominant x86 counterpart and a powerful virtual execution environment for software development, validation, verification, and test that considers the relevant RISC-V ISA extensions for cloud deployment. Specifically, commercial cloud systems make use of hardware features that are currently unavailable in RISC-V virtual environments (not to mention the lack of specific RISC-V hardware). These features include the virtualization, cryptography and vectorization for which Vitamin-V will add support in three virtual environments: QEMU, gem5 and cloud-FPGA prototype platforms. Vitamin-V focuses and will provide support for EPI-based RISC-V designs for both the main CPUs and cloud-important accelerators (for memory compression). We will add the compiler (LLVM-based) and toolchain support for the ISA extensions. Moreover, novel approaches for the validation, verification, and test of software trustworthiness will be developed considering. Vitamin-V will port and evaluate several cutting-edge VMMs and container suites (i.e. VOSySmonitor, KVM, QEMU, Docker, RustVMM, Kata containers), cloud management software (i.e., OpenStack, and Kubernetes) together with their software and libraries dependencies (e.g. JVM, Python); and AI (i.e Tensorflow) and BigData applications (Apache Spark). These software suites are representative of the three cloud setups that will be demonstrated: classical (OpenStack), modern (Kubernetes), and serverless (RustVMM, Kata, Kubernetes). The cloud setups will be benchmarked against relevant AI (i.e., Google Net, ResBet, VGG19), BigData (TPC-DS), and Serverless applications (FunctionBench, ServerlessBench). Vitamin-V aims to match the software performance of its x86 equivalent while contributing to RISC-V open-source virtual environments, software validation and cloud software suites.

Keywords: risc v,isa extensions,cloud stack,virtualization,containers,cloud management,serverless,virtual machine monitors,software validation,anomaly detection,compiler,toolchain,ai,bigdata