Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
WaveMove: Revolutionizing Wave Energy Conversion for Consistent and Cost-Effective Renewable Power (WAVE-PRO)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

OE Systems, founded in 2020 in Gothenburg, Sweden, tackles the challenges of grid stability, efficiency, and high operational costs in offshore renewable energy. Our technology, WaveMove, integrates advanced wave energy converters with offshore wind farms, enhancing energy output and optimizing space use by capturing both vertical and horizontal wave motions, delivering consistent power. Currently at TRL 5, WaveMove has been validated through industry partnerships and successful wave tank testing. The market potential includes boosting the efficiency of existing offshore wind turbines, developing combined wind and wave energy sites, electrifying offshore platforms, and reducing diesel use in remote locations. Our Total Addressable Market (TAM) is estimated in the billions, with Europe as a primary focus due to its extensive coastline and established wind infrastructure. Our business model includes power studies, EPC deliveries, service, and online optimization. We plan to initiate commercial installations of 250 kW units by 2027, starting with energy studies and expanding to full-scale deployments. WaveMove offers significant societal, economic, and environmental benefits, enhancing energy security, generating substantial revenue, minimizing ecological footprints, and supporting marine biodiversity. Our technology aligns with EU renewable energy targets and global climate change initiatives. Our experienced team, supported by a strong board, is committed to delivering this groundbreaking technology while prioritizing gender balance and inclusivity in our growth strategy. EIC Accelerator funding is crucial for transitioning WaveMove from prototype to commercial unit, allowing us to address technical challenges, conduct real-world validations, and position WaveMove for market success. This funding will drive growth, attract investments, and ensure our technology contributes significantly to the offshore renewable energy landscape.

Keywords: wave energy conversion,renewable energy,offshore wind integration,grid stability,sustainable energy,energy optimization,marine energy,cost effective power,offshore energy infrastructure
Deciphering the Regulatory Logic of Cortical Development (EpiCortex)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 1999643.0
EU funding (EUR): 1999643.0
Participants: 1
Project status: SIGNED

The mammalian cortex is the most complex region of the brain responsible for higher cognitive functions. Abnormal cortical development often translates into prominent neuropsychiatric diseases, which affect different neuronal subtypes with unique molecular and morphological features. Increasing evidence suggests that epigenetic regulation is essential for cortical development but how multiple regulatory layers are coordinated to specify distinct neuronal lineages in vivo remains unclear. My team and I recently applied single-cell RNA-seq, single-cell ATAC-seq together with cell-type-specific DNA methylation and 3D genome measurements to map the regulatory landscape of neural differentiation at a single embryonic stage in vivo. However, the process of neuronal subtype specification involves multiple distinct waves of differentiation over several consecutive days. Therefore, to decode the molecular logic of temporal cellular identity in the cortex, I will comprehensively dissect the interplay between gene expression, chromatin topology and epigenetics in specifying cell fate. In order to accomplish this, I will build upon my extensive experimental and computational expertise to (1) map the regulatory landscape of the developing mouse cortex across multiple regulatory layers and timepoints in single cells; (2) identify and validate cis-regulatory elements via a novel massive parallel cell-type specific reporter assay in vivo and (3) determine the functional consequences of perturbing enhancers and silencers using a highly multiplexed single-cell approach. Collectively, EpiCortex will provide unprecedented insights and establish new paradigms into the interplay between transcription factors, epigenome dynamics and gene expression in development. It will allow us to better understand the molecular logic of lineage specification in the mammalian cortex and more precisely define, compare and ultimately engineer cellular identities for therapeutic and regenerative purposes

Keywords: cerebral cortex,neurogenesis,development,single cell,epigenomics,in vivo,lineage specification,gene regulation,dna methylation,3d genome organization,crispr,transcription factors
Improving adult numeracy/employability. An adult numeracy platform that contextualises maths, allowing the learner to develop the confidence, motivation and resilience to maximize their employability. (Numeracy for Life)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Ireland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 920556.0
EU funding (EUR): 920556.0
Participants: 1
Project status: SIGNED

N4L addresses the high cost and scheduling difficulties of teacher-led interventions and the inadequacies of existing numeracy products for adult learners. The N4L platform, accessible via mobile devices, offers optimal learning outcomes through brief, impactful interactions. By reducing math anxiety and enhancing confidence, motivation and resilience, N4L aims to improve adult learner’s numeracy and employability. Currently in trials, N4L strives for a 50-75% success rate across a range of KPI’s, significantly boosting economic productivity. Utilising advanced AI, N4L personalises learning based on user profiles and emotional states, ensuring relevant, contextualised education. This innovative approach promises to transform numeracy learning, fostering a confident and capable workforce.

Keywords: numeracy,maths,confidence,adult employability and upskilling for the betterment of individuals and their families understanding inherent maths anxieties and emotional responses to learning
zero-CO2 cemeNt ThRough cArBonation of cAlcium Silicates and aluminateS (CONTRABASS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,Greece,Switzerland,France,India,Romania,United Kingdom,Germany,Finland,Norway,Poland
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 2171340.0
EU funding (EUR): 2171340.0
Participants: 20
Project status: SIGNED

CONTRABASS: zero-CO2 cemeNt ThRough cArBonation of cAlcium Silicates and aluminateS. We live in a world of concrete. According to the Global Cement and Concrete Association (GCCA) cement is consumed at a rate of ~150 tonnes each second, and it accounts for approximately 8% of all CO2 emissions and 7% of industry energy use. In order to mitigate the negative environmental impacts of concrete, Carbon Capture and Utilization (CCU) is the best available strategy: the GCCA estimates that CCU technologies will represent up to 42% of the CO2 reductions necessary to reach the net zero industrial objective in 2050. The CONTRABASS MSCA-DN will act in this framework, in the pathway towards the zero-CO2 cement and concrete production, building a high-quality doctorate network (DN) to investigate the fundamental physico-chemical processes governing the Carbonation of the clinker phases and the cement paste, as well as the subsequent formation of Calcium Carbonate Cements (CCCs). The carbonation ability of clinker and cement is well known, yet for a full implementation of CCCs by 2050, there is an urgent need of fundamental knowledge on the carbonation process. In this scenario, the CONTRABASS DN aims to contribute to the global reduction of CO2 emissions by accelerating the implementation of Calcium Carbonate Cements, developing fundamental knowledge, practical know-how, and a generation of well-trained specialists to overcome the main challenges identified by our industrial and academic partners. CONTRABASS has 5 main objectives: 1. To identify the carbonation mechanisms of the clinker components, specially calcium aluminates 2. To understand the carbonation processes of the C-S-H gel and the cement paste 3. To unravel the factors that govern CaCO3 polymorphism, nucleation and growth rates 4. To build databases for thermodynamic and reactive-transport modelling of carbonation 5. To communicate effectively the benefits of CCCs to society, media and policy maker.s

Keywords: carbonation curing,cement recarbonation,calcium carbonate nucleation and growth,co2 reutilization,clinker hydration and carbonation
Multilevel Orders of Corruption in Central Asia (MOCCA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Sweden,Kyrgyzstan,Turkmenistan,Uzbekistan,Kazakhstan,Switzerland,Türkiye,Finland,Lithuania,Denmark,Czechia,Tajikistan,Estonia
Call: MSCA Staff Exchanges 2021 (HORIZON-MSCA-2021-SE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 1656000.0
EU funding (EUR): 1656000.0
Participants: 24
Project status: SIGNED

Corruption has become a buzzword in both academic and policy debates over the last three decades. The initial view that “corruption greases the wheels of economic growth” in the newly independent states of Africa and Asia has lost its validity in the light of the current ever-growing global coalition against corruption, spearheaded by Transparency International and the World Bank. Despite the unrelenting global anti-corruption efforts, one thing seems clear: There is no such thing as a remedy to this “cancer”. In the light of the obvious failure of global anti-corruption initiatives, there has been a growing call to rethink the existing approaches, arguing for the necessity to understand better what corruption is, why it occurs, and what we can do to stop it. MOCCA is a research and staff exchange programme intended to contribute to the global and national efforts of understanding and counteracting corruption by conducting research on the multilevel orders of corruption in five countries in post-Soviet Central Asia (Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan). This will enable the MOCCA team to: 1) gather original empirical data (based on research solidly grounded in fieldwork) on the interplay between international law norms, national laws, and local legal cultures and informal norms in Central Asia and their implications for understanding corruption and its societal effects; 2) engage with and situate our research in relevant theoretical debates and thereby advance scholarly debates on (anti-) corruption by developing new conceptual, methodological and comparative approaches to study and understand it; and 3) provide strategic intelligence for EU-based political and economic actors interested or already working in the region, and to inform international organisations and decision-makers in the EU and Central Asia on ways to combat corruption and improve the business and investment climate, the rule of law and governance in the region.

Keywords: corruption law and society governance central asia post soviet studies sociology of law
Making the Invisible Visible: Computational Sensing and Imaging via Folding Non-Linearities (CoSI-Fold)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2024-12-01
End date: 2029-11-30
Duration (months): 60.0
Total project cost (EUR): 1499560.0
EU funding (EUR): 1499560.0
Participants: 1
Project status: SIGNED

By leveraging a radically new digital sensing approach, the CoSI-Fold program strives to achieve a quantitative breakthrough in performance while unlocking qualitatively new and previously unthinkable applications. The emerging field of computational sensing has opened up new horizons, such as the imaging of the Black Hole. However, mainstream digital sensing still relies on decades-old ideas from Claude Shannon's seminal 1948 paper, which laid the foundations of sampling theory and catalyzed the "Digital Revolution." Despite immense progress, capturing high-dynamic-range (HDR) signals at high digital resolution (HDRes) while maintaining low power consumption (LPC) remains a significant challenge. Implementing Shannon's method via analog-to-digital converters (ADCs) introduces fundamental bottlenecks, including quantization noise and saturation due to limited dynamic range (LDR). These limitations are conspicuously evident in cases like the 1986 Chernobyl Accident, where excessively HDR radiation went unrecorded due to LDR dosimeters, resulting in loss of lives. Bottlenecks in current digital pipelines clearly necessitate a paradigm shift. The CoSI-Fold program capitalizes on an alternative methodology that simultaneously unlocks HDR and HDRes capabilities with LPC. CoSI-Fold harnesses a synergistic melding of novel hardware and mathematical algorithms, representing the core principle of computational sensing. The analog-domain folding of HDR inputs eliminates the well-known clipping problem while also reducing the quantization noise floor. Mathematically principled algorithms then computationally unfold the LDR folded samples. The quantum leap brought by CoSI-Fold lies in the comprehensive convergence of theoretical, algorithmic, and hardware innovations it introduces. Our feasibility tests indicate the potential to revolutionize the fields of Audio and Acoustics, Biomedical and Healthcare Monitoring, and Computational Imaging, which are the focus of CoSI-Fold.

Keywords: computational sensing,sampling theory,harmonic analysis,inverse problems,unlimited sensing
SDD-AGE-MS: a proteomics tool for characterizing protein organization and plasticity in biomolecular condensates. (SDD-AGE-MS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 217965.12
EU funding (EUR): 217965.12
Participants: 1
Project status: SIGNED

In living systems, biological processes are orchestrated by proteins organized into dynamic assemblies. Cells regulate protein assembly and disassembly through various mechanisms, with subcellular compartmentalization playing a critical role in creating a microenvironment that control biological reactions. Notably, not all compartments rely on membranes for segregation; biomolecular condensates, for example, are membraneless organelles formed through a network of multivalent interactions. While noteworthy progress has been made in identifying the proteins partitioning in biomolecular condensates and understanding the forces driving phase separation; how proteins interact forming assemblies within condensates remain poorly understood. This knowledge gap is primarily due to the lack of system-wide approaches capable of effectively characterizing condensates, which are often low in abundance, large, dynamic, and highly heterogeneous. In this study, we introduce SDD-AGE-MS, an innovative proteomics method designed to characterize the architecture of condensates. By integrating SDD-AGE, an electrophoretic technique commonly used to visualize SDS-resistant high molecular weight assemblies, with mass spectrometry (MS), we aim to map the migration profiles of SDS-resistant proteins and link them to protein assemblies. This project will make significant contributions on multiple levels: (i) conceptually, by unveiling and resolving sub-assembly organization of condensates; (ii) methodologically, by introducing a system-wide approach for characterizing high molecular weight assemblies in cells; and (iii) translationally, by providing insights into the mechanisms driving condensate formation and their transition to pathological aggregates, as observed in neurodegenerative diseases.

Keywords: proteomics,protein condensates,protein aggregates,method development
The neural language of song: Brain mechanisms for sensorimotor syntax control (NeuralSyntax)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Israel
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Our motor sequences obey syntax rules. From tying shoes to giving a speech, choosing the next action requires our brain to remember past actions, bridge across many seconds, and apply rules that create hierarchical syntax. Whereas past studies revealed how primary motor cortex drives actions, we poorly understand the transition mechanisms by which the brain strings actions into hierarchical variable sequences. The key obstacle is identifying deep hierarchical syntax rules in behavior and in neural sequences. This obstacle is met by studying birdsong that naturally segments to sequences of syllables. In the zebra finch, juveniles learn once from a tutor and fix a single sequence driven by a robust song-locked activity. Here, to study hierarchical syntax rules I will use canaries: virtuosos that learn and adapt such rules along and across seasons. Canaries produce a huge repertoire of songs that enable separate analysis of neural states and syllable acoustics when studying their rich and dynamic syntax rules. My previous work in canaries identified hidden neural states that keep a memory of sung syllables over several seconds and predict upcoming transitions. Here, I leverage this model to dissect transition mechanisms and elucidate: 1) neural activity in the premotor nucleus HVC that underlies flexible transitions between syllables; 2) integration of auditory and thalamic inputs for applying hierarchical syntax rules to select the next syllable; 3) neural state dynamics when adapting syntax rules for new songs; and 4) seasonal remodeling of HVC via neurogenesis. We use imaging, electrophysiology, and neural network simulations that integrate data across behavior, neural activity, and circuit levels of analysis. Our work will map the process by which basal ganglia and thalamocortical circuits generate and adapt hierarchical syntax rules over time, sensory, and social contexts, and might offer insights to dysfunction of motor sequence control in maladaptive conditions.

Keywords: electrophysiology songbird neuroscience neural network simulation syntax learning and generation motor sequences
Empirical and theoretical assessment of the links between inner speech and insight (InSpeech)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium,United Kingdom
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-01
End date: 2027-01-31
Duration (months): 24.0
Total project cost (EUR): 191760.0
EU funding (EUR): 191760.0
Participants: 2
Project status: SIGNED

Inner speech is a cognitive process of silent communication with oneself. Inner speech is driven by natural language and thus is deeply rooted in human culture while it pursues such cognitive functions as thinking, memory, planning, etc. In order to reach a more holistic knowledge of our inner voice, it requires integrating the approaches of semiotics, culture studies, linguistics, psychology and neuroscience. Exploring the functions and experience of inner speech in everyday situations drives the development of inner speech methodologies and raises the awareness of the role of culture in human cognition. One of the distinguishing features of human cognition is its unique problem solving ability. While previous research has indicated the connections between inner speech and problem solving, it remains unclear whether inner speech is experienced similarly in different types of problem solving, such as analytical problem solving or a sudden Aha! effect. The given research project explores whether the specific dimensions of inner speech (inner speaking and inner hearing) and its phenomenological properties (dialogic, condensed, etc.) can be associated with insight, or Aha! effect, and analytical types of problem solving. The research will integrate methodological paradigms from insight, semiotics and inner speech studies to quantitatively and qualitatively assess the experience of inner speech in insight and non-insight problem solving during an empirical experiment. The project aims at providing the applicant with interdisciplinary training, strengthening of the previous experience and widening career perspectives in the EU. The results of the project will explore the underlying connections between inner speech and insight problem solving, expanding our understanding of the role of natural language in human cognition. The project will also drive the public awareness of the inner speech and facilitate the development of new research methodologies for its exploration.

Keywords: inner speech,insight,aha effect,problem solving,semiotics,vygotsky,cognitive psychology