Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Disrupting the sports nutrition market with a healthy, high-performance, bee product-based energy gel in highly innovative compostable packaging (METAMORFOSIS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-09-01
End date: 2022-08-31
Duration (months): 36.0
Total project cost (EUR): 2711011.5
EU funding (EUR): 1897708.05
Participants: 1
Project status: CLOSED

While energy gels are widely used in endurance sports, they are not currently user- or environmentally-friendly: A) hard-to-use empty gel packaging made from single use plastic ends up littering the countryside, B) they are far from natural or healthy, C) taste unpleasant and D) offer sub-optimal sports performance. In fact, gels are considered a necessary evil, yet it’s a fast-growing market of almost €1bn in 2017, expected to reach €1.76bn by 2025 (8.1% CAGR 2017-27). Metamorfosis' gels address these issues: they are packed in our compostable packaging, which is hygienic and non-sticky; are made with delicious bee products and other 100% natural, easy-to-digest healthy ingredients; and offer world-class sports performance. It is a world-first for a gel to be in compostable packaging, which we will patent and licence to 3rd parties. Our project is backed by research and endorsed by sports stars and nutritionists. In the Phase 2 project we will refine gels & packaging, industrialise Metamorfosis, register all IPR and generate pre-launch awareness & a strong sales pipeline. We are Food Sourcing Specialists, S.L., a well-established Barcelona-based healthy/sports food producer, distributor & retailer with deep sector knowledge, over 650 B2B clients & an online B2C retail store. We will conduct our own distribution in Spain/Andorra and distribute in other countries via our existing network of international suppliers/distributors. Our aim is to disrupt the market, capture 2% thereof 5 years from product launch (€35m/year net sales) & become the leading 100% natural sports nutrition brand, while reducing plastic pollution & protecting bee colonies, including a 1% donation of revenues to BeeLife (bee protection organisation). Total budget: €2,711,012. Grant requested: €1,897,708. After 5 years of commercialisation, we expect a 42% gross margin, 37% IRR and €7.5m cumulative EBITDA.

Keywords: apiculture,bees,beekeeping,sports,nutrition,eu honey,compostable,biodegradable,packaging,colony collapse disorder,natural ingredients,healthy food,energy gels,single use plastic,environment
Communities on Food Consumer Science (COMFOCUS)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Integrating activities and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Italy,Spain,Germany,Spain,Finland,Slovakia,Norway,Slovenia,Netherlands,Denmark,United Kingdom,Portugal
Call: Integrating Activities for Starting Communities (H2020-INFRAIA-2020-1, 2020)
Start date: 2021-03-01
End date: 2025-02-28
Duration (months): 48.0
Total project cost (EUR): 4997142.31
EU funding (EUR): 4997142.3100000005
Participants: 16
Project status: SIGNED

COMFOCUS brings together, integrates on European scale, and opens up key national and regional research infrastructures in the inherently interdisciplinary field of food consumer science to all European researchers, from both academia and industry, ensuring their optimal use and joint development. Its mission is to advance the food consumer science community beyond its current level of fragmentation that is preventing it from being the data-rich science area contributing to the societal problem of (un-)healthy food choices. As a library of meta data and digital service tools, the COMFOCUS Knowledge platform is developed as an easily accessible focal point for all European researchers to make this happen within the principles of FAIR and Responsible Research & Innovation (RRI) data use. COMFOCUS achieves this through a coordinated set of activities on networking, joint research and transnational and virtual access to key research infrastructures. Networking activities foster the culture of co-operation between 10 key research infrastructures, and beyond in interaction with academic and industry research users and technology developers. Joint research activities develop the harmonisation protocols for measurement and research procedures both in the area of conventional self-reported data and more objective emerging food consumer science methodologies. The transnational and virtual access activities ensure that researchers from outside the consortium are supervised to become experienced with this new way of working, while also contributing to the data infrastructure from which the COMFOCUS Knowledge platform can further grow into the future. Promotion of transnational and virtual access and dissemination of COMFOCUS outcomes and innovations for maximum impact will be supported by a Stakeholder Forum from relevant bodies such as consumer organizations, food industry, retail, NGOs, and policy makers at national and EU levels.

Keywords: food consumer science,research infrastructure,community,harmonised measures,virtual access toolbox,transnational access,inter disciplinary,fair,responsible research and innovation
Sustainable Smart Mobile Devices Lifecycles through Advanced Re-design, Reliability, and Re-use and Remanufacturing Technologies (sustainablySMART)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Technologies for Factories of the Future
Action type: Research and Innovation actions
Countries involved: Austria,Austria,Germany,Germany,Ireland,Germany,Cyprus,Finland,Finland,Poland,Finland,Sweden,Netherlands
Call: Re-use and remanufacturing technologies and equipment for sustainable product lifecycle management (H2020-FoF-2015, 2015)
Start date: 2015-09-01
End date: 2019-10-31
Duration (months): 50.0
Total project cost (EUR): 7005292.5
EU funding (EUR): 6989278.0
Participants: 18
Project status: CLOSED

sustainablySMART will make a change to the life cycle of mobile information and communication devices by developing new product design approaches (including enhanced end-of-life performance, re-use and re-manufacturing aspects; i.e. implementing “Design for a Circular Economy”) for smartphones and tablet computers on the product and printed circuit board level, and by new re-/de-manufacturing processes with improved resource efficiency through (1) enhanced sorting capabilities and speed (optimized sorting efficiency), (2) automated disassembly of mobile IT devices for extraction of reusable components / modules, better material separation and depollution of end-of-life devices (increase value creation out of discarded devices significantly to create an economic advantage over shredding processes), and (3) high-quality performance testing (batteries) and rework (semiconductors and modules) of reusable components/modules (creating a market push for reusable parts through enhanced availability for repair and cascade reuse)

Keywords: remanufacturing factory,sorting automation,disassembly automation,semiconductors,modularity,printed circuit boards,smarttphone,tablet,digital voice recorder,energy efficiency
Mesoscale Brain Dynamics: Computing with Neuronal Pathways (BRAINCOMPATH)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2016-02-01
End date: 2021-01-31
Duration (months): 60.0
Total project cost (EUR): 2498915.0
EU funding (EUR): 2498915.0
Participants: 1
Project status: CLOSED

Brain computations rely on proper signal flow through the complex network of connected brain regions. Despite a wealth of anatomical and functional data – from microscopic to macroscopic scale – we still poorly understand the principles of how signal flow is routed through neuronal networks to generate appropriate behavior. Brain dynamics on the 'mesoscopic' scale, the intermediate level where local microcircuits communicate via axonal pathways, has remained a particular blind spot of research as it has been difficult to access under in vivo conditions. Here, I propose to tackle the mesoscopic level of brain dynamics both experimentally and theoretically, adopting a fresh perspective centered on neuronal pathway dynamics. Experimentally, we will utilize and further advance state-of-the-art genetic and optical techniques to create a toolbox for measuring and manipulating signal flow in pathway networks across a broad range of temporal scales. In particular, we will improve fiber-optic based methods for probing the activity of either individual or multiple neuronal pathways with high specificity. Using these tools we will set out to reveal mesoscopic brain dynamics across relevant cortical and subcortical regions in awake, behaving mice. Specifically, we will investigate sensorimotor learning for a reward-based texture discrimination task and rapid sensorimotor control during skilled locomotion. Moreover, by combining fiber-optic methods with two-photon microscopy and fMRI, respectively, we will start linking the meso-level to the micro- and macro-levels. Throughout the project, experiments will be complemented by computational approaches to analyse data, model pathway dynamics, and conceptualize a formal theory of mesoscopic dynamics. This project may transform the field by bridging the hierarchical brain levels and opening significant new avenues to assess physiological as well as pathological signal flow in the brain.

Keywords: neocortex,thalamus,neuron,calcium indicator,imaging,in vivo,sensorimotor,optical fiber,two photon,fmri,axonal pathway,mesoscopic
IntraVenous ANtibiotic Compounding Automation (IVANCA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Finland
Call: Accelerating the uptake of nanotechnologies, advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2014, 2014)
Start date: 2015-03-01
End date: 2015-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The aging population is driving the demand for health care services to an all-time high. This places pressure to find novel measures of producing health services more efficiently and at a lower cost. In the sphere of hospital pharmacies, antimicrobials are a leading group of medications. The number of doses administered in EU-based hospitals alone is 330 million. In hospital use antibiotics often need to be administered through intravenous (IV) infusion. The manual compounding of IV antibiotics is very time consuming, especially if conducted in the recommended aseptic conditions. Manual compounding is, however, often conducted in non-aseptic conditions, which exposes the IV medicines to microbial contamination. Contaminated medicines are a serious risk to patients. Hospitals have already begun to adopt automation in care provision. The currently available compounding robots are not, however, capable of rapidly producing large quantities of IV medicines. The demand levels clearly exceed their capacities. Newico is a pharmacy and laboratory automation company with a sound client base. With the support of the IVANCA project (IntraVenous ANtibiotic Compounding Automation), the goal of Newico is to commercialize a novel, stand-alone IV antibiotic compounding system. The I.V.ICON boasts a capacity level equivalent to 5,5 ward staff. As the I.V.ICON operates in an aseptic environment the produced IV medicines have a significantly longer shelf life (up to 30 times) and their risk of microbial contamination is in the proximity of zero %. Over ten years of use, the I.V.ICON is expected to bring 2,4 Meur savings to the hospital as compared to manual ward based compounding. The IVANCA project feasibility study is needed to conduct a more detailed market study, learn from an ongoing hospital pilot, make draft plans on arranging manufacturing, elaborate on user needs, conduct an IPR and regulation study in main target markets and make a more detailed business plan.

Keywords: robotics,automation,compounded sterile products,intravenous infusions,antibiotics
HyBalance (HyBalance)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Innovation actions
Partnership: FCH2 (Art-187)
Countries involved: Germany,Sweden,Belgium,France,Denmark,Denmark
Call: Demonstrating the feasibility of central large scale electrolysers in providing grid services and hydrogen distribution and supply to multiple high value markets (H2020-JTI-FCH-2014-1, 2014)
Start date: 2015-10-01
End date: 2020-09-30
Duration (months): 60.0
Total project cost (EUR): 15803441.25
EU funding (EUR): 7999370.8
Participants: 8
Project status: CLOSED

Power-to-Gas (PtG) is an innovative energy concept which will help to incorporate flexibility into future energy systems, increasingly characterised by the use of fluctuating renewable electricity. One PtG option, dubbed Power-to Hydrogen (PtH2) is to produce hydrogen from water electrolysis applying cheap renewable electricity in times of surplus and providing it for re-electrification in times of electricity shortages or to other hydrogen end-users, whatever promises the best business opportunities. It has been shown by recent studies that these can be best exploited, if PtH2 simultaneously supplies hydrogen to more than one end-use sector. The combination of electricity and mobility sectors has been earmarked as being specifically relevant, promising high utilization of the electrolysers and hence possible revenues. It is the purpose of the HyBalance project to demonstrate the concept of multi-sectoral hydrogen end-use in the renewable energy friendly environment of wind-rich Denmark at Megawatt scale with a PtH2 plant. A group of partners representing all steps along the renewable electricity to hydrogen to end-use value chain have convened to develop a PtH2 demonstration plant. This plant will be designed for combined operation providing both grid balancing services and hydrogen for industry and as a fuel for transport in the community of Hobro in the Danish province of Nordjylland. The plant will be used to demonstrate its feasibility to identifying potential revenue streams from PtH2 under today’s and future constraints (regulatory environment, state-of-art of key technologies), simultaneously applying most recent developments for hydrogen distribution and storage. Relevant applications in the hydrogen production site’s proximity are: hydrogen refuelling stations for fuel cell cars and buses in Hobro, local industry and, as perspective, hydrogen storage in salt caverns located in Hvornum and Lille Torup.

Keywords: hydrogen,electrolyser,electrolysis,mutiple hydrogen markets,grid,balancing,demonstration
Energy Saving Aseptic System to Empty Concentrates out of Aseptic Bags for the Juice Production Process. (ASEPTIC-VACBID)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: Spain
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-1-2015, 2015)
Start date: 2016-03-01
End date: 2016-06-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

SEPPELEC, S.L. is an engineering company, we are specialists in process engineering for drink factories and facilities. The ultimate goal we seek in ASEPTIC-VACBID project is to develop an automatic and aseptic equipment to empty concentrated juices out of aseptic bags. We have already developed a semi-automatic prototype achieving aseptic conditions to empty bags up to 25L. The objective of this project is to scale-up the aseptic system in a complete automatic equipment to empty the standard 250L and 1,500L bags used in the juice industry. By incorporating an ASEPTIC-VACBID system into the production process, capable to empty 18,000L of concentrate per hour, the juice industry will reduce energy consumption costs of €150,000 per year (1.324.422 kW), representing an improvement of 13% in the energy efficiency of the whole process. The use of water is reduced by 30.000L per hour and the automated equipment also reduce personal costs.

Keywords: aseptic processing,juice industry
NEOlithic MEDiterranean diet through stable ISotope analysis (NEOMEDIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-31
End date: 2021-06-28
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The introduction of farming (6th millennium BC) fundamentally transformed the Western Mediterranean but prehistorians have long argued about the causes, tempo and completeness for this change. Stable isotope analysis (SIA) of ancient human bones provides a novel approach for addressing this problem directly reconstructing diet and crudely assessing the transition from foraging and fishing to farming. However, there are some uncertainties with this approach precluding the accurate determination of the extent to which Neolithic ‘farmers’ still relied on marine foods. This is important as a prominent model for the so-called ‘Neolithisation’ is of population replacement and of a complete change to domesticated cereals and animal products. The existing state-of-the-art relies on analysing bone protein from skeletal remains and relate these measurements to data obtained from potential food sources. NEOMEDIS aims to advance this approach by breaking down the protein into their constituent amino acids and analysing the carbon, nitrogen and sulfur isotopes in these individual molecules tracing different dietary components to obtain an approach that will provide a more accurate dietary reconstruction. NEOMEDIS will provide detailed dietary reconstructions for 75 Neolithic individuals from the NW Mediterranean dating from the first arrival of farming to the Middle Neolithic to examine the change over this period. Skeletal remains from key sites are already in hand, benefit from excellent chronologies and contextual information provided by leading expert collaborators in Spain, France and Italy. The fellowship will furnish the applicant in next-generation methods skills in SIA that are beginning to be widely applied in ecology, archaeology and geochemistry using facilities that are not yet available in her country. The applicant will obtain a unique skill set and the independence to pursue her own bioarchaeological research following a clear route towards professional maturity.

Keywords: stable isotopes,palaeodiet,neolithic,mediterranean basin,csia
Functional magnetic materials for biomedical applications (BioMagMat)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2017-12-01
End date: 2019-05-31
Duration (months): 18.0
Total project cost (EUR): 149997.0
EU funding (EUR): 149997.0
Participants: 1
Project status: CLOSED

A range of new medical therapies and diagnostics based on magnetic nanomaterials have recently been proposed. These include cancer therapies, stem cell therapies, microfluidic diagnostic devices and immunoassays. However, very few biotechnology magnetic nanomaterials are currently available commercially; most investigators fabricate their own. This is a serious limitation to the development of this emerging area within nanomedicine. This proposal aims to transfer a number of magnetic nanomaterials from the University physics laboratory where they were developed as part of an ERC AdG grant into an existing small company where they can then be made available to researchers across the world on a commercial basis.

Keywords: nanomagnetism,thin films,biotechnology,functional materials,nanomaterials
Neural regulation of the immune system in the Gut (Neu-i-Gut)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 159815.04
EU funding (EUR): 159815.04
Participants: 1
Project status: CLOSED

Maintenance of tissue health requires a variety of cellular and molecular networks. The immune system comprises panoplies of cell subsets that can sense endogenous and exogenous factors to ensure efficient surveillance and defense. Similarly, the nervous system harbors distinct neuronal populations that sense and respond to ever-changing stimuli. Interestingly, discrete neuronal and immune cells in the intestine were shown to share anatomical confinements and influence each other’s function, forming neuronal immune cell units that act as rheostats of gut physiology. Nevertheless, whether brain-derived signals control enteric immune functions and intestinal homeostasis remains elusive. Importantly, neurological dysfunction induced by stroke correlates with severe intestinal problems in humans; including infections, inflammation and colon-rectal cancer. We propose to investigate how Central Nervous System (CNS) signals control intestinal immune homeostasis and how alteration of brain-derived signals induce gastrointestinal disease. We will explore how intestinal homeostasis and immune-mediated diseases are regulated in the context of stroke, which is a major Public Health concern. To achieve this, we propose to employ genetic, cellular and molecular approaches to decipher how brain signals and pathways specifically shape gastro-intestinal immune homeostasis and what is their relevance in intestinal inflammation and cancer. To this end, stroke and gastro-intestinal disease models, together with powerful tractable, chemogenetic technology, will be employed. Astonishing preliminary data revealed that stroke severely disrupts intestinal lymphocyte homeostasis, promoting their exodus from the gut to other organs. We foresee this project as groundbreaking, establishing the link between altered brain signals and intestinal physiology, shedding light into the intricate relationships between the CNS and the gastrointestinal immune system in the context of stroke, and beyond.

Keywords: stroke,intestinal immunity,dreadd,colo rectal cancer,infections,gut brain axis