Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Designation and Management of Marine Reserve Networks (DEMARN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2010-11-01
End date: 2015-10-03
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 2
Project status: CLOSED

This research will explore physical elements of the environment and their spatial character, principles of conservation science, human needs and institutional constraints for the purpose of establishing marine protected areas. The goal is to identify institutional and societal constructs that are frequently left out of decision-making for marine protected area design and management. Research conclusions will be based on comparison of spatial outcomes. The researcher will synthesize approaches that have addressed the challenges of working in a multi-faceted, high-use marine environment in which there are varying levels of information, challenges of cooperation between local and regional managers, scientists and users and difficulty soliciting the input of relevant stakeholders. Major phases of the research are: 1) development of a typology of the designation of terrestrial reserves in Israel and marine reserves in the territorial waters of countries along the Mediterranean Sea; 2) review and application of appropriate decision support tools that can address at least two identified challenges in the Israeli context: connectivity of reserves and stakeholder participation; and 3) comparison of outcomes from the use of decision support tools chosen based on the country context needs and actual reserve design and management plans proposed by the nature protection authorities in Israel. This research can inform regulators, policymakers and conservationists about what various theoretical views and values mean when applied to conditions in the field (both in terms of physical resources and institutional constructs) and how and to what extent real-world outcomes engender preferred practices based on ecosystem based management and integrated coastal zone management for marine reserves in a network context.

Keywords: coastal zone ecosystems and management,environmental protection
COMPOSITE MEMBRANES WITH METAL ORGANIC FRAMEWORKS FOR HIGH EFFICIENCY GAS SEPARATIONS (COMMOF)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Türkiye
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2010-11-01
End date: 2015-02-21
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The objective of this proposal is identification of composite membranes consisting of polymers and highly selective metal organic framework (MOF) particles for ultra-high efficiency carbon dioxide separations using atomistically detailed computational techniques. Energy efficient separation of gas mixtures is of enormous industrial, social and economical importance since energy has significant impacts on economic and technologic growth of countries. Energy research is directed towards separation of carbon dioxide due to the urgency of energy supply security, climate change problems and economic competitiveness. This proposal aims to examine polymer/MOF composite membranes that will exhibit exceptional performance for separation of carbon dioxide from methane to increase the energy content of the natural gas. The first and only study in the literature on computational modeling of a polymer/MOF composite membrane has been recently done by Dr. Keskin. The results showed that polymer/MOF composite membranes represent an important avenue for enhancing the performance of polymer membranes. Even if only one polymer is considered there are thousands of MOFs that could be potentially used as filler particles in polymer matrices. Given the infinite number of polymer/MOF combinations, using computational screening to select the most promising polymer/MOF pairs before investigating a large amount of time and resources into composite membrane fabrication is crucial. This proposal suggests a coordinated plan of employing state-of-the art atomically detailed simulations for screening highly selective MOFs and applying continuum modeling for polymer/MOF composite membranes for high performance gas separation applications. This proposed study will be the first in the literature to unlock the potential of composite membranes made of MOFs which is currently a mystery.

Keywords: energy,gas separation,carbon dioxide capture,storage,disposal (climate change),membrane,natural gas,metal organic frameworks
NANOSTRUCTURED ALUMINA WAVEGUIDES FOR DUAL-OUTPUT BIOSENSING: STRESS INDUCED FABRICATION AND CHARACTERIZATION (NANOSTRBIOSENS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Türkiye
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2011-02-01
End date: 2015-01-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Most commercially available optical biosensors only measure changes in the refractive index of a solution very near the sensor surface. Information given by this approach is limited to the amount of analyte molecules linked into receptors on the sensor surface. In some cases, understanding complex bio-events is constrained when available data is based solely on refractive-index-change measurements via characteristics of the reflected light (intensity, polarization or phase). Scattering measurements need to be accompanied along with reflection measurements in order to determine the organization of molecules on a surface as well. This proposal calls for the development of nanostructured waveguides made of a thin layer of alumina (Al2O3) which would produce and control dual sensor outputs, specifically, total internal reflection (TIR) and surface enhanced Raman scattering (SERS) signals. Single-mode waveguides with structured surface will present a significant advantage over current optical biosensors by providing better information about both the binding and organization of protein molecules via polarization maintained reflection and scattering. After atomic layer deposition of single-mode waveguide alumina film, its surface modification will be done by a mechanics driven fabrication method called thermal stress induced hillock formation. The main objective of this proposal is to fabricate and characterize a nanostructured alumina waveguide that will provide the following crucial advantages over the optical biosensor approach: 1) The possibility for dual-output with fine tuning, 2) a more complete understanding about the organization of molecules, 3) an unprecedented sensitivity for a label-free optical sensor, which will analyze information down to sub pmol/cm2 because of its enhanced electromagnetic (EM) field, and 4) the ability to control the molecular binding characteristics of the surface.

Keywords: nanotechnology,materials engineering,biosensors,nanostructure,alumina,waveguides,evanescent wave,total internal reflection,surface enhanced raman scattering,hillocks,atomic layer deposition
Search for novel mechanisms to increase the critical temperature of a superconductor (NANOHIGHTC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Portugal
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The main objective of the proposal is to find new ways to increase substantially the critical temperature of a superconductor, determine the experimental feasibility of the theoretical predictions and, in collaboration with experimentalists, find the experimental setting with an optimal enhancement of superconductivity. In order to pursue this goal we investigate: (1) finite size effects in different type of superconductors - Pb, fullerides, cuprates and iron pnictides - , (2) novel forms of superconductivity based on Efimov states, (3) superconductivity in systems that do not thermalize, namely, with quasiparticle distributions different from Fermi-Dirac. In (1) the main task is to identify the grain size and shape, amount of disorder and type of interaction for which Tc increases the most and assess its practical/experimental feasibility and its potential for technological applications. In (2) and (3) we first aim to identify the properties of the superconducting state and its robustness under thermal and quantum fluctuations and then explore the optimal setting to observe an enhancement of superconductivity. Moreover, in order to gain theoretical understanding of some of these strongly interacting systems, we employ the AdS-CFT correspondence (see background) in order to put forward a quantitative, though effective, description of certain aspects of high temperature superconductors and systems close to quantum critical points.

Keywords: superconductivity,cold atom,nanograins,thermalization,anderson localization
Next generation small-scale biomass combustion technologies with ultra-low emissions (EU-ULTRALOWDUST)

Framework: FP7 — Cooperation
Programme: Energy
Destination: Renewables for heating and cooling
Action type: Collaborative project
Countries involved: Austria,Germany,France,Germany,Germany,Austria,Germany
Call:  (FP7-ENERGY-2010-2, 2010)
Start date: 2011-01-01
End date: 2014-03-31
Duration (months): 39.0
Total project cost (EUR): 4229951.47
EU funding (EUR): 2884995.0
Participants: 9
Project status: CLOSED

The UltraLowDust project aims at the demonstration of an European approach for ultra-low emission small-scale biomass combustion based on three novel technologies which cover the whole range of residential biomass heating applications. For pellet and woodchips combustion a new ultra-low emission boiler technology operating at almost zero CO, OGC and PM emissions will be demonstrated. Moreover, a new stove technology based on optimised air staging and an automated control system which shows significantly decreased PM, CO and OGC emissions compared with present stoves will be introduced. For PM emission reduction in old and new logwood boilers, old stoves as well as boilers for non-wood biomass fuels, a new ESP system will be demonstrated. These three technologies shall after successful demonstration define a new state-of-the-art regarding ultra-low emission biomass combustion covering an intelligent combination of primary and secondary measures. The technologies will be demonstrated within field tests over two heating seasons. Moreover, the project aims at the development of market introduction plans for the new technologies which will be supported by a market study as well as techno-economic analyses and overall impact assessments based on the results of the field tests. Additionally, the project aims at the development of recommendations for future emission limits under consideration of the results achieved, which shall then be discussed with national and EU authorities active in legislation making. To reach these aims a consortium of partners from 3 EU-countries consisting of the manufacturers of the three key technologies, research institutions which will support the industrial partners with their expertise in biomass combustion, one partner who is active in the field of international networking and policy making as well as, as coordinator, an internationally recognised engineering company, experienced in market studies and technology assessments has been formed.

Keywords: biomass,residential heating,low emission,stove,boiler,filter
Molecular Recognition: Understanding Proteins Adsorption to Inorganic Surfaces (PROADS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Understanding how proteins adsorb to inorganic surfaces is important in many biotechnological applications, including the design of medical implants, fabrication of antibacterial surfaces and biomeneralization. Many studies have been carried out in order to examine how proteins interact with inorganic entities or surfaces; still, it is not clear how proteins “sense” the inorganic surface. The aim of the proposed research is get insights into the fundamental rules that govern protein adsorption. The approach will combine the use of two powerful tools: atomic force spectroscopy and self-assembled monolayers. It will undertake a reductionist methodology and study the adsorption of individual amino acids to chemically well-defined surfaces, functionalized with self-assembled monolayers, using single-molecule spectroscopy. The experimental approach that will be developed, in the course of the project, will be useful as a tool for other researches in the field. Additionally, findings from this research will allow the design of antibacterial surfaces, new biomaterials and peptides that interact with inorganic surfaces or particles in a controlled manner to form composite materials.

Keywords: peptides,amino acids,self-assembled monolayers,surfaces,recognition,atomic force spectroscopy,biomaterials
Role of Skeletal Stem Cells in Bone Repair (SKELETAL STEM CELLS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

It is estimated that 2% of the population sustain fractures annually, which in Europe corresponds to approximately 15 millions fractures and in France 1 million fractures. Although bone exhibits strong regenerative properties, delayed unions and non-unions still occur at a frequency of 5 to 10% in all skeletal injuries leading to patient disability and high societal cost. Bone repair is dependent on the proliferation and differentiation of skeletal stem/progenitor cells. The exact origins and functions of these cells are not clearly understood. Our long-term goal is to elucidate the mechanisms of skeletal stem cell recruitment during bone regeneration in order to support the development of new cell based therapies for bone repair. In the past 10 years, I have established several mouse models of bone repair combined with cell lineage analyses in vivo. These approaches based on genetic labeling and bone transplantation allow tracking the fate of tissues and cells during bone development and repair. In Aim 1, we will track mesenchymal lineages in development and repair, in order to understand how adult skeletal stem cell populations are established in bone. Aim 2 will directly compare the contribution of local versus systemic sources of skeletal stem cells and the effects of environmental factors such as extreme trauma on their relative contributions. Aim 3 will functionally assess the molecular regulation of skeletal cell fate decisions within bone marrow and periosteum (which lines the outer surface of bone) during fracture healing. Following my postdoctoral training, I have worked for 5 years at University of California San Francisco to develop an independent research program supported by extramural funding. This project will use my expertise accumulated over the years and research support is crucial to pursue my goals and establish a new research team at INSERM U781, Necker Hospital for Sick Children in Paris starting in the spring of 2010.

Keywords: orthopaedics,fracture repair,mouse models,in vivo cell lineage analyses
Free Radical Pharmacology: Generators, Targets and Therapeutic Implications (RADICAL PHARMACOLOGY)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2011-02-01
End date: 2015-01-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Personalised Medicine is the next revolution in medicine. It is anticipated that we will see a dramatic shift towards predictive diagnostics and mechanism-based, individualised therapies. Cardiovascular diseases (CVD) are the leading causes of death and disability and in Europe cause over 4.3 million deaths (48%) per annum. Since the mechanisms of CVD are not understood, the majority of current therapeutic approaches are symptom-orientated and imprecise. Therefore, we need innovative strategies to develop mechanism-based drugs, i.e. drugs, which target the cause of disease. A prerequisite for this is a detailed knowledge on the causes of CVD. One such highly promising mechanism of CVD is oxidative stress, i.e. the increased occurrence of oxygen radicals, an area of utmost medical significance but where so far all clinical trials using antioxidant treatment have failed. Here three major aims are proposed: to identify targetable sources of radical signals that are relevant for CVD, to establish strategies for reversing the molecular damage caused by oxidative stress, and to develop new markers for diagnosis of CVD in humans and mechanism-based treatments. Thereby, a conceptual shift in treating oxidative stress will be achieved. In the long-term, this research will provide measurable outcomes in improved health, new products, and economic benefits by lowering the public health burden and facilitate the growth of biotechnology and pharmaceutical industries in Europe. This will result in a net decrease of health burden and will ensure sustainability of the healthcare system. This fellowship will also help to further attract leading international researchers to Europe to support the internationalisation of the European health and medical research, and to enhance EU’s reputation as place of excellence in biomedical research and translation.

Keywords: health sciences,personalised medicine,heart disease,stroke,diabetes,drug discovery,diagnostics
A welfare comparison between trade and migration: Local public goods, redistributive policies, and housing markets (MIGRATION AND TRADE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2011-03-15
End date: 2013-03-14
Duration (months): 24.0
Total project cost (EUR): 50000.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The research project has as general objective to provide further insights to the welfare comparation between trade in goods and migration. A complementary objective is to provide an adequate framework for the discussion of migration policies. There are three issues related to migration flows that are important from a practical point of view and are the object of this research project: The effects of migrants on the cost of providing public goods, the effects of migrants on welfare of local labour force, and the effects of migrants on housing markets. The project aims to build general enough models to analyze the welfare consequences of free mobility of persons within countries when there are public goods that can be congested, to design policies to regulate international migration, and to propose realistic policies to compensate deserving losers from migration flows (some of them based on housing markets). More specifically, the project plans to construct a model with local public goods and congestion levels endogenously determined and, for such a model, define and explore the welfare characteristics of the competitive equilibrium for different forms of financing public goods and find conditions for obtaining gains from migration. On the other hand, the project wants to analyze non linear second best redistributive policies that make Pareto gains from migration attainable. Finally, the project aims to introduce explicitly housing markets in a General Equilibrium model and analyze how housing price equilibrium vary when migration is freed, and how tax policies based on housing market prices can act a regulatory migration device and as a compensation device of possible losers with migration.

Keywords: general equilibrium,non-convexities,gains from trade,migration,local public goods,congestion,rediatribution.
Formal Analysis and Modeling of Human-Automation Interaction (FMHAI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2011-11-01
End date: 2015-10-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The automotive industry is transforming to embrace opportunities afforded by inexpensive yet powerful computers, sensors, and wireless technology. New vehicle designs call for implementation of sophisticated infotainment systems, mobile communication technology, and navigation systems, as well as safety features such as sensors for pedestrian detection and collision avoidance. Next generation automobiles will employ extensive use of automation for speed and lane control, and parking assist. While continued electrification and automation of the automobile are inevitable, nevertheless, obstacles remain. Key among these is the design and development of interfaces that comfortably link drivers to largely automated, and highly connected vehicles through elegant, efficient and safe interactions. Currently there is no common, industry-wide design and specification language for describing human-computer interaction, built and packaged to integrate safety, efficiency, and driver satisfaction. Therefore, the first objective of the proposed project is to develop such a language and syntax. The second objective is to use formal mathematical techniques to define a generic set of “bad” properties that contribute to human error and frustration during interaction. A third objective is to establish a set of “good” design patterns, encapsulated in a formal mathematical description, productive of consistent, efficient, and elegant human-automation interaction throughout the entire suite of automotive connectivity and automation features. The final objective is to develop a systematic process and tools for the application of the abovementioned objectives. The project will be conducted at and in close collaboration with engineering design teams in Europe (Opel and Vauxhall). The results would be applicable to any system involving human-machine interaction.

Keywords: intelligent interfaces,modelling tools,human computer interaction