Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Unified digital booking platform promoting local tourist services (GET LOCAL)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2020-01-01
End date: 2020-04-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

OTAs (Online Travel Agencies) have revolutionised the tourist and hospitality industry by the democratisation of booking information to consumers. Their focus on pricing and “standardised” offers has resulted in reduced income for hotels and local tourist service providers, as well as their power to reach potential customers. They operate in monopoly, USA dominated, and create dependency on hotels and local service providers, who cannot afford an efficient digitalized tool and struggle to distinguish themselves among the numerous offers. GET LOCAL AG is a young and dynamic company from Zurich, Switzerland created with the aim of deploying a digital, B2B booking platform, GET LOCAL, enabling hotels and tourist service providers to combine forces and offer added value to their international guests in the form of exclusive local deals and packages. GET LOCAL operates via local branches, which are joint ventures between GET LOCAL AG and a local service provider and/or Destination Management Organisation to enable swift mobilization of local resources. It employs an in-house-developed software platform which allows high scalability and a competitive advantage to alternative solutions. It also applies Artificial Intelligence to generate personalised suggestions for tourists based on their previous experiences and demographics. We have already launched a prototype in Zurich, Basel and Vienna, with main hotel brands and numerous local service providers already on-board. GET LOCAL has received several innovation awards and featured in numerous sites. With this SME Instrument project, we intend to prepare a technical and commercial roadmap to grow faster and more efficiently, launching GET LOCAL in at least 45 cities by 2025 (5-year post-project), thus raising up to €13.4 M revenues per local Joint Venture. We intend to create 40+ new ventures in European destinations and 5 beyond Europe, thereby creating about 150 new positions (of which 10-15 in our holding company).

Keywords: online travel agency ota,destination management,software platform,leisure management,local sme support,new business model
Epileptic Seizure Prediction System (ESPS) - Predicting and preventing epileptic seizures based on respiratory biofeedback & machine learning. (ESPS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Ireland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-07-01
End date: 2019-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Epilepsy is one of the most common nervous system disorders and affects more than 50M people worldwide. The majority of new-onset cases occur in elderly and children. Currently there is no cure for epilepsy. Although antiepileptic drugs can help, one third of all patients do not respond to any pharmacological intervention. This staggering number has not changed in decades, despite over 14 new therapies entering the market. The unpredictable nature of seizures causes the largest burden for patients as it literally disrupts their lives. Patients with several seizures a week are hesitant to leave the house & find it hard to obtain employment. Reliably predicting seizures enables an independent life for the patient and at the same time reduces healthcare costs caused by clinician visits, injuries & caretaking. iBreve’s new patent-pending wearable technology analyzes respiratory patterns in real-time, enabling market applications for seizure prediction, respiratory treatment & stress management. iBreve’s technology received interest from Harvard’s Boston Children’s Hospital to be included in clinical trials for seizure detection & prediction. The ESPS machine learning algorithm calculates seizure probability & intensity and if desired an alert is sent to the patient’s caregiver. The tracking and analysis of seizures can be shared with clinicians & allows to personalize treatment. Main objective of this feasibility study is the development of a comprehensive business plan to evaluate the opportunities & risks of introducing ESPS into the homecare market. All project activities follow the Healthcare Innovation Cycle methodology & are structured around 4 development pillars - Technology, Market & Business, Clinical and Regulatory. The introduction of ESPS is prone to disrupt the epilepsy market by reducing treatment costs per patient by up to 70%. Thus, saving 14B€ in health care costs in Europe alone and creating a major shift towards preventive & personalized treatment.

Keywords: epilepsy,epileptic seizures,self care,real time monitoring,breathing pattern analysis,machine,learning
An unprecedented water-recycling system for washing, rinsing and drying of thermal insulated containers within the Food Industry (OPTAINER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Belgium
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2020-08-01
End date: 2022-10-31
Duration (months): 27.0
Total project cost (EUR): 2590885.0
EU funding (EUR): 1813619.5
Participants: 1
Project status: SIGNED

Big food retailers use thermic insulated containers for the safe and efficient transportation of temperature-controlled food to retail stores facilities. These containers are cleaned in the logistic centers and reused countless number of times to ship food over and over again. Container cleaning is a crucial step in food operations and aspects like the effectiveness of the cleaning, the cost-efficiency of the process, the environmental impact and the water remaining in the container after the cleaning are of great importance. Optainer is an automated modular cleaning station that can be perfectly integrated into the logistic chains of food retailers. This is the first automated solution that can wash, rinse and dry food containers very fast (1’ 40’’), at low cost (around 0.5 €/container), with low energy (1 kWh/container) and low fresh water consumption (<4 l/container of fresh water). Food retailers will save money, water and energy and they neither will spend too much time cleaning containers nor will have to allocate a part of their workforce to these activities. At the same time, they will be sure that containers are perfectly cleaned and the process is automatically controlled. We are LVP Engineering and Constructions, a Belgian company bringing experience 40 years in the development and construction of machines for several industries. OPTAINER will be the flagship product of LVP Cleantec, a series of machines for the automated cleaning of insulated food containers, a field in which we are leaders. Standing out of competitive solutions, OPTAINER will foster our business (we estimate 109.1 M€ turnover in the 5th year of commercialization and 123 new jobs in the company). At the same we will reduce energy and water consumption of a process that is suboptimal and risky.

Keywords: food chain,industrial food container washer,cleaning station,food container
Glia-derived factors in innate lymphoid cell sensing and intestinal defence (GliaInnateSensing)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Portugal
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-07-01
End date: 2021-12-31
Duration (months): 78.0
Total project cost (EUR): 2270000.0
EU funding (EUR): 1144742.55
Participants: 2
Project status: CLOSED

The interplay between intestinal microbes and immune cells ensures vital functions of the organism. However, inadequate host-microbe relationships lead to inflammatory diseases that are major public health concerns. Innate lymphoid cells (ILC) are an emergent family of effectors abundantly present at mucosal sites. Group 3 ILC (ILC3) produce pro-inflammatory cytokines and regulate mucosal homeostasis, anti-microbial defence and adaptive immune responses. ILC development and function have been widely perceived to be programmed. However, recent evidence indicates that ILC are also controlled by dietary signals. Nevertheless, how ILC3 perceive, integrate and respond to environmental cues remains utterly unexplored. We hypothesise that ILC3 sense their environment and exert their function as part of a novel epithelial-glial-ILC unit orchestrated by neurotrophic factors. Thus, we propose to employ genetic, cellular and molecular approaches to decipher how this unconventional multi-cellular unit is controlled and how glial-derived factors set ILC3 function and intestinal homeostasis. In order to achieve this, we will assess ILC3-autonomous functions of neurotrophic factor receptors. ILC3-specific loss and gain of function mutant mice for neuroregulatory receptors will be used to define the role of these molecules in ILC3 function, mucosal homeostasis, gut defence and microbial ecology. Sequentially we propose to decipher the anatomical and functional basis for the enteric epithelial-glial-ILC unit. To this end we will employ high-resolution imaging, genome-wide expression analysis and tissue-specific mutants for define target genes. Our ground-breaking research will establish a novel sensing program by which ILC3 integrate environmental cues and will define a key multi-cellular unit at the core of intestinal homeostasis and defence. Finally, our work will reveal new pathways that may be targeted in inflammatory diseases that are major Public Health concerns.

Keywords: innate lymphoid cells,mucosal immunology,neurotrophic factors,glial cells
Studies in Harmonic Analysis and Discrete Geometry: Tilings, Spectra and Quasicrystals (HARMONIC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Israel
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2016-12-01
End date: 2022-11-30
Duration (months): 72.0
Total project cost (EUR): 1260625.0
EU funding (EUR): 1260625.0
Participants: 1
Project status: CLOSED

This proposal is concerned with several themes which lie in the crossroads of Harmonic Analysis and Discrete Geometry. Harmonic Analysis is fundamental in all areas of science and engineering, and has vast applications in most branches of mathematics. Discrete Geometry deals with some of the most natural and beautiful problems in mathematics, which often turn out to be also very deep and difficult in spite of their apparent simplicity. The proposed project deals with some fundamental problems which involve an interplay between these two important disciplines. One theme of the project deals with tilings of the Euclidean space by translations, and the interaction of this subject with questions in orthogonal harmonic analysis. The PI has recently developed an approach to attack some problems in connection with the famous conjecture due to Fuglede (1974), concerning the characterization of domains which admit orthogonal Fourier bases in terms of their possibility to tile the space by translations, and in relation with the theory of multiple tiling by translates of a convex polytope, or by a function. A main goal of this project is to further develop new methods and extend some promising intermediate results obtained by the PI in these directions. Another theme of the proposed research lies in the mathematical theory of quasicrystals. This area has received a lot of attention since the experimental discovery in the 1980's of the physical quasicrystals, namely, of non-periodic atomic structures with diffraction patterns consisting of spots. Recently, by a combination of harmonic analytic and discrete combinatorial methods, the PI was able to answer some long-standing questions of Lagarias (2000) concerning the geometry and structure of these rigid point configurations. In the present project, the PI intends to continue the investigation in the mathematical theory of quasicrystals, and to analyze some basic problems which are still open in this field.

Keywords: tiling,spectral set,fuglede conjecture,quasicrystals,convex polytopes,fourier analysis,spectral gaps,equidecomposability
HYBRID MAGNETIC SUPERCAPACITORS (Hy-MAC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-06-01
End date: 2017-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The purpose of Hy-MAC is to assess both technical and economic viability of using magnetic nanocomposites based on the combination of carbon nanoforms (graphene) with magnetic nanoparticle as hybrid supercapacitors. These hybrid magnetic materials have shown to exhibit unique supercapacitive properties, which can be significantly enhanced by application of an external magnetic field. Thus, the specific capacitance increases up to a 500% by applying an external magnetic field. Taking advantage of these results, in this proposal we plan to fabricate and test prototype supercapacitive devices exhibiting better performances than those reported for commercial supercapacitors.

Keywords: hybrid magnetic materials,magnetic nanoparticles,hybrid supercapacitors,graphene,magnetic nanocomposites
Development of a Functionalised Biomaterial Scaffold to Treat Multiple Sclerosis (Multiple Sclerosis)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-08-01
End date: 2020-07-31
Duration (months): 24.0
Total project cost (EUR): 175866.0
EU funding (EUR): 175866.0
Participants: 1
Project status: CLOSED

Multiple sclerosis (MS) is a chronic inflammatory immune-mediated demyelinating disease of the central nervous system (CNS), which affects 700,000 people in Europe, with total annual healthcare costs of over €27.3 billion. Current available treatments for progressive MS have modest effects on relapse symptoms but do not modify disease progression. Critically there are currently no licensed disease-modifying treatments for progressive MS. My strategy will represent a disease modifying treatment for progressive MS. I will fabricate and optimize the loading and release profile of the an anti-TNFR1 antibody from ROS-responsive collagen spheres, I will assess the biocompatibility, bioactivity, and neuroprotective effect of the anti-TNFR1 antibody functionalized ROS-responsive collagen hollow spheres in organotypic cerebral slice cultures. I will evaluate the efficacy of the anti-TNFR1 multifunctional spheres against chronic neurodegenerative pathology in a preclinical model of progressive MS that mimics the pathology seen in progressive MS patients. Progress to completion will be reviewed by a Research and Professional Development Plan which will provide both discipline-specific and complementary technical training and generic and complementary transferable skills training (intellectual property, leadership skills, motivation skills, communication skills, regulatory affairs, clinical trial design, reimbursement strategies, medical device evaluation and regulatory affairs). I will benefit from Prof Pandit’s and Dr John O’Dea’s (Crospon Limited) (inter-sectorial secondment) international collaborative network in the field of neurodegenerative diseases. This training will facilitate me to achieve my future career goals of achieving a position of professional maturity, diversity and independence by establishing my own research group at a leading European academic institution and enable me to translate innovative therapeutic interventions to the clinic setting.

Keywords: functionalised biomaterials,tissue engineering,biomedical engineering,scaffolds
Welcoming ERA Chair to Centre of excellence in nutrigenomics for optimising health and well-being in the Institute of Animal Reproduction and Food Research, Polish Academy of Sciences (WELCOME2)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: ERA chairs
Theme: Attracting and mobilising the best talents
Action type: Coordination and support actions
Countries involved: Poland
Call: ERA Chairs (H2020-WIDESPREAD-2018-2020-6, 2019)
Start date: 2020-10-01
End date: 2026-09-30
Duration (months): 72.0
Total project cost (EUR): 2499887.5
EU funding (EUR): 2499887.5
Participants: 1
Project status: SIGNED

The main objective of WELCOME2 is to upgrade, extend and unlock the research potential of Institute of Animal Reproduction and Food Research to achieve excellence on sustainable basis and fully participate in ERA. An outstanding researcher with high leadership skills (ERA Chair holder) and her/his group will be permanently employed at IARFR to lead interdisciplinary research that will lay grounds to Centre of Excellence in nutrigenomics for optimising health and well-being. ERA Chair is envisaged as a Deputy Director for Science at Institute’s new premises after their construction is completed. In parallel, we will implement SWOT-driven structural changes for responsible research and effective science management. Introduction of internal policies on GLP, OA, ODM and ethics will make IARFR a competitive and credible ERA-recognised centre. Upgraded HR unit will underpin proficient execution of C&C principles and OTM-R values, fostering ERA priorities of gender equality, research freedom and training, and thus increase Institute’s attractiveness for excellent mobile researchers. Under Chair’s guidance we will advance our research management/administrative skills and improve Institute's capacity to compete successfully for international funds. WELCOME2 received support from authorities, industry and research stakeholders, and demonstrates a strong synergy with European Structural Investment Funds. Project’s impacts feed into regional and national smart specializations, as well as Horizon2020 Societal Challenges, HorizonEurope Pillar2 Global Challenges and European Industrial Competitiveness and UN Sustainable Development Goals. We will disseminate WELCOME2 outcomes to external stakeholders in open trainings, scientific seminars and Knowledge Arena Workshops, and this way modify research and innovation landscape of region and country. To maintain all research-related policies and favourable working conditions beyond project completion a Sustainability Plan was prepared.

Keywords: food science,nutrition,prophylaxis of diet related diseases,omics
Independent test of the battery health in electric vehicles (AVILOO bcheck)

Framework: Horizon 2020 — Societal Challenges
Action type: SME instrument
Countries involved: Austria
Call: H2020-EIC Accelerator pilot –SME Instrument - Green Deal (H2020-EIC-SMEInst-2018-2020-4, 2020)
Start date: 2020-10-01
End date: 2022-09-30
Duration (months): 24.0
Total project cost (EUR): 3184067.5
EU funding (EUR): 2228847.25
Participants: 1
Project status: CLOSED

Batteries are subject to degradation over time, which results in a decrease in available power and range of electric vehicles (EV).When buying a used electric car, it is therefore of great importance for buyers and sellers to know the exact state-of-health of the battery as this determines its value to a high degree. AVILOO developed the only existing independent, trustworthy and objective battery testing system for electric vehicles. The AVILOO b:check will bring evidence for the quality of batteries in used electric cars. The b:check is a radically new, breakthrough product opening new markets with the potential for rapid growth. AVILOO’s b:check will enable an independent and reliable battery check to receive an exact report on the actual state-of-health of any battery in any electric vehicle. The AVILOO b:check is applied during a simple test drive and therefore provides an exact result of the SOH. Current solutions are either commercially inefficient because extremely expensive, not accurate or not at all independent. The AVILOO b:check project focuses on the further development and market uptake of the AVILOO products and services. The objectives will be reached by continuous developing, optimizing, testing, demonstrating, and validating the AVILOO products and services. AVILOO will contribute to the plans and measures set by the European Union on tackling climate and environmental-related challenges within the Green Deal. AVILOO‘s b:check supports the acceleration of the shift to sustainable and smart mobility and a zero-pollution ambition for a toxic-free environment. AVILOO's b:check paves the way to avoid CO2 emissions by (1) inducing an extension of the lifespan of batteries used in EVs and by (2) allowing a so called second life usage for batteries not suitable for EVs any more. AVILOO's management team has extensive experience in building, managing, and growing international businesses.

Keywords: battery check,battery lifetime extension,electric vehicle,used electric car,reliable,exact,independent