Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Advanced materials for lean burn combustion tiles using laser- Additive Layer Manufacturing (L-ALM) (ASLAM)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Clean Sky
Action type: Article 171 of the Treaty
Partnership: CLEAN-SKY (Art-185)
Countries involved: United Kingdom,United Kingdom
Call:  (SP1-JTI-CS-2013-01, 2013)
Start date: 2013-10-01
End date: 2016-08-31
Duration (months): 35.0
Total project cost (EUR): 995398.0
EU funding (EUR): 745619.0
Participants: 3
Project status: CLOSED

The objective of this project is to develop materials and processes for use in laser additive layer manufacture, which are capable of meeting the stated requirement for advanced, high temperature nickel superalloys (with high levels of gamma prime forming elements) for use in novel combustion components for lean burn engine developments. The Participants will review the current state of the art and determine a shortlist of three potential alloys for development. In collaboration with the Topic Manager, one alloy will be selected for development. A representative application for the selected alloy will be defined and appropriate specifications determined for geometrical accuracy, surface finish and materials properties. The first phase of experimental work will develop a Additive Layer Manufacturing process, optimised for the properties determined above. In a second phase, this 'best known' method of manufacture will be used to manufacture multiple batches of part geometries and test specimens in order to provide sufficient statistical confidence in the data to allow use of this process for the manufacture of parts for use in an engine-realistic environment.

Keywords: additive layer manufacture,laser,nickel,super-alloy,combustion,tile
Manoeuvring Noise Evaluation Using Validated Rotor State Estimation Systems (MANOEUVRES)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Clean Sky
Action type: Article 171 of the Treaty
Partnership: CLEAN-SKY (Art-185)
Countries involved: Italy,Italy
Call:  (SP1-JTI-CS-2013-01, 2013)
Start date: 2013-10-01
End date: 2016-05-31
Duration (months): 32.0
Total project cost (EUR): 1538576.42
EU funding (EUR): 1124537.0
Participants: 4
Project status: CLOSED

The MANOEUVRES project aims at the demonstration of the feasibility of an innovative approach to noise abatement in rotorcraft terminal manoeuvres based on in-flight measurement of the rotor state. In particular, a novel sensor system for rotor tip-path-plane angle of attack will be designed, developed and tested together with the necessary signal conditioning, in order to assess its capabilities in view of application on production helicopters. This sensor will be integrated on-board an actual helicopter for on-ground demonstrations and validation. Based on the availability of this new sensor, an algorithm will be developed that, together with other vehicle data (such as airspeed), will enable the run-time estimation of the emitted noise. This algorithm will exploit an acoustic data prediction process resulting from a dedicated study, which includes the analysis of the dependency of acoustic emissions on actual (unsteady) flight conditions as based on steady, quasi-steady and full-unsteady approaches, as well as the examination of the sensitivity of the emitted noise with respect to perturbations of a given trajectory. The results from the acoustic prediction processes considered will be correlated with experimental data provided by the GRC5 consortium. A human-machine interface will be designed according to aeronautical standards to provide useful information to the pilot in terms of emitted noise, allowing for flying low noise procedures with improved awareness and effectiveness. Preliminary testing will be carried out to assess compliance of this noise indicator with piloting requirements. The team involves Politecnico di Milano technical university; University of Roma Tre; Vicoter, a SME specializing in mechanical design, analysis, and testing; and Logic, a SME specializing in the design, implementation and testing of certified software and hardware for aeronautics, including rotorcraft systems.

Keywords: manoevring rotorcraft noise,unsteady rotorcraft aeroacoustics,rotor flapping in-flight measurement,rotorcraft noise monitoring,pilot acoustic indicator.
Gust Load Alleviation techniques assessment on wind tUnnel MOdel of advanced Regional aircraft (GLAMOUR)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Clean Sky
Action type: Article 171 of the Treaty
Partnership: CLEAN-SKY (Art-185)
Countries involved: Italy,Germany,Italy,Israel,United Kingdom
Call:  (SP1-JTI-CS-2013-01, 2013)
Start date: 2014-02-01
End date: 2016-11-30
Duration (months): 34.0
Total project cost (EUR): 2323860.92
EU funding (EUR): 1742895.69
Participants: 5
Project status: CLOSED

The aim of Gust Load Alleviation techcniques assessment on wind tUnnel MOdel of advanced Regional aircraft (GLAMOUR) proposal is a technological optimisation and experimental validation through an aero-servo-elastic innovative WT model of gust load alleviation control systems for advanced Green Regional Aircraft. The expected benefits of such technologies are mainly the mitigation of gust load responses, the reduction of peak stresses so to potentially decrease sizing loads and consequently increase the weight saving. Most generally, the capability to control the load distribution spanwise could contribute to other global targets such as fatigue lifetime as well aeroelastic and aerodynamic performances. GLAMOUR project has these main objectives: - Validate the Load Alleviation techniques based on control architectures defined by ITD member - Develop of alternative control schemes - Design and manufacturing of a wind tunnel model representing half GRA aircraft dynamically scaled so to be used for experimental validation purpose. The model will be equipped with active split ailerons and elevator to be used for active control - Perform wind tunnel test with and without LA controls to validate both the proposed control schemes and the new ones developed by the consortium. To this aim, the wind tunnel proposed for experimental activity will be equipped with an ad hoc developed gust generator so to inspect the whole flight envelope and frequency bandwidth typical of the considered aircraft - Draw a final assessment on the global benefits achievable using LA technologies in both design and off-design flight conditions. Apart from the Project management workpackage (WP0), that includes exploitation and dissemination, the tasks to be done inside of the project are included in six workpackages.

Keywords: load alleviation,aeroelasticity,wind tunnel testing
EXTRApolation and technical and economic study of a LASER beam welding technology (extra-laser) (EXTRA-LASER)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Clean Sky
Action type: Article 171 of the Treaty
Partnership: CLEAN-SKY (Art-185)
Countries involved: Greece,Germany
Call:  (SP1-JTI-CS-2013-01, 2013)
Start date: 2013-10-01
End date: 2014-09-30
Duration (months): 12.0
Total project cost (EUR): 150000.0
EU funding (EUR): 112499.0
Participants: 2
Project status: CLOSED

Recent developments in the metallurgical field offer now laser weldable Al-alloys of the 2xxx series such as 2198 (Al-Cu-Li) with high structural efficiency index due to their high strength and low density. In the present project, butt and T shape welds from third generation Al-Li aluminum alloys will be manufactured with the available in-house laser beam welding facilities. Upon on the information gained in the project and in-house experience of the manufacturer (HZG) a large, typical aeronautical structure with stiffeners will be manufactured and exploited in this project. A similar structure will be manufactured by the Topic Manager with the conventional riveting process. The projects aim to document the two processes (LBW and riveting), calculate the manufacturing costs of both structures, perform mechanical tests on the structures and finally compare the two structures in terms of the mechanical performance to manufacturing cost index. Besides cost, the environmental footprint of the two different structures will be calculated, as well the extrapolation of the LBW process from Laboratory to Industrial environment. To this end, the intermediate processes will be documented, risk assessment will be performed and a manufacturing plan of the typical aircraft structure will be constructed. Of course, any industrial repercussion during the implementation of the technology in the manufacturing plant will be taken into account during calculation of the implementation plan.

Keywords: laser beam welding,manufacturing cost,recurring and non-recurring cost,aircraft structure,manufacturing plan,abc costing,sub-processes,environmental footprint,implementation plan
manufacturing by SLM of TItanium FAN wheels. Comparison with a conventional manufacturing process (TIFAN)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Clean Sky
Action type: Article 171 of the Treaty
Partnership: CLEAN-SKY (Art-185)
Countries involved: Spain,Spain
Call:  (SP1-JTI-CS-2013-01, 2013)
Start date: 2013-10-01
End date: 2015-03-31
Duration (months): 18.0
Total project cost (EUR): 199989.2
EU funding (EUR): 142000.0
Participants: 3
Project status: CLOSED

The global objective of the Eco-Design ITD is to reduce the product environmental impact while keeping competitiveness of the aeronautic industry. The TIFAN project addresses the manufacturing by SLM of fan wheel of an air cooling unit that is currently made of stainless steel. New environmental friendly fan wheels made of Titanium alloy TA6V will be developed. 5 fan wheel demonstrators will be fully manufactured and characterised within the project. The TIFAN project involved the comparison between SLM and conventional bar machining process in terms of material properties (Rm, Rp0.2, E, E%, fatigue, surface roughness and corrosion resistance), environmental impact (Life Cycle Assessment) and cost. The project will be focused in the next value aspects: • Developing at the maximum the versatility that offers of SLM manufacturing technology. • Applying advanced in-process and post-built surface quality improvement strategies. • Optimizing powder usage efficiency by defining improved powder recycling methodologies and minimizing the volume required for support structures • Optimizing fan wheel design applying full advantage of SLM possibilities: light-weight design, lattice structures. • Decrease the environmental impact and manufacturing process by means of component’s weight and waste raw materials and CO2 emissions reduction. The objective of the TIFAN project is not only to manufacture of demonstrators, but to identify the critical factors that could give rise to a further manufacturing cost and weight reduction as well as mechanical performance improvement. Some of these factors comprise a significant progress beyond the state of the art. The success of TIFAN’s goal will have technical, industrial and environmental impacts. Real impact will be measured and compared to traditional manufacturing processes. On the other hand, technical conclusions of TIFAN will be transferable to other components, fostering in this way the competitiveness of European Aeronautical Companies.

Keywords: selective laser melting (slm),titanium alloy,aircraft demonstrators,mechanical properties,fatigue,corrosion resistance,environmental impact,cost analysis,surface finishing,bar machining.
High speed metallic material removal under acceptable surface integrity for rotating frame (HIMMOVAL)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Clean Sky
Action type: Article 171 of the Treaty
Partnership: CLEAN-SKY (Art-185)
Countries involved: Spain,Spain,Belgium
Call:  (SP1-JTI-CS-2013-01, 2013)
Start date: 2013-11-01
End date: 2015-10-31
Duration (months): 24.0
Total project cost (EUR): 599676.0
EU funding (EUR): 449757.0
Participants: 3
Project status: CLOSED

The HIMMOVAL project aims to develop a new rapid metal removal concept under acceptable surface integrity for fabricating typical jet engine components made of high resistant super alloys that will be based on smart use of non-conventional machining methods, namely water jet technologies and low plasticity burnishing surface treatment, optimized conventional machining and a well-defined sequence of processes. The concept to be developed will show high productivity, low cost, the capability to create special geometries or cavities and the robustness to be translated to a real production situation. The feasibility of a radical improvement of material removal rate when using conventional machining with defined cutting edges through cryogenic cooling or creative machining strategies will also be explored. The generated results will enable optimum selection of removal processes together with their parameters under stringent surface integrity requirements for high resistant alloys. Moreover, the rapid removal concept will contribute to deliver the geared open rotor demonstrator technologies addressed within the CSJU SAGE2 project to demonstration. The HIMMOVAL consortium is integrated by 1 research organisation, 1 university and 1 SME. .

Keywords: rapid material removal,surface integrity high resistant,super alloys,alternative technologies(wj,edm,low plasticity burnishing,laser),high performance machining,numerical modelling and simulation
Automatic detection and monitoring of consciousness (COMONIN)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: France
Call:  (ERC-2013-PoC, 2013)
Start date: 2014-03-01
End date: 2015-08-31
Duration (months): 18.0
Total project cost (EUR): 157360.0
EU funding (EUR): 149820.0
Participants: 2
Project status: CLOSED

When patients recover from coma, determining their level of consciousness can be difficult, even for an experienced clinician. Our goal is to provide a Consciousness Monitoring Index: a robust method to detect and quantitatively monitor the extent to which a human being is or is not conscious. Using electrodes attached to the scalp, we monitor the electro-encephalographic (EEG) signal which reflects ongoing brain activity. We have discovered and filed a patent for several mathematical indices which can be easily computed from the EEG, and which, alone or in combination, provide a continuous indicator of whether the person is or is not conscious. Our empirical studies in patients with coma, vegetative state show that our EEG-based markers can (1) accurately determine whether a patient is or not conscious at the time of testing; (2) establish how consciousness fluctuates from moment to moment; (3) predict, in a statistical manner, the capacity of the patient to recover consciousness. In this project, we propose to establish the scientific validity, technical feasibility, market potential, business model, and legal context for two distinct services that could be provided: (1) an off-line computer-based service for automated analysis of existing clinical EEG recordings, taking the form of a web server where clinicians would upload these data and receive a summary of indicators of consciousness. (2) an on-line bedside monitor of consciousness, taking the form of a tablet PC and dedicated EEG amplifier constantly displaying a scrolling view of indicators of consciousness, for real-time use by clinicians and by families, possibly with real-time feedback to patients. Our application is primarily intended for adult patients with disorders of consciousness, their doctors and their families, but its market could be much larger, and we will explore its possible extension to anaesthesia, sleep disorders, epilepsy, pediatric populations, professional and personal use.

Keywords: 249830
Design, verification and synthesis tools for cardiac pacemaker software (VERIPACE)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: United Kingdom
Call:  (ERC-2013-PoC, 2013)
Start date: 2014-01-01
End date: 2014-12-31
Duration (months): 12.0
Total project cost (EUR): 163817.2
EU funding (EUR): 149103.0
Participants: 1
Project status: CLOSED

Typical treatment for declining heart function or arrhythmias involves expensive surgical implantation of cardiac pacemakers, medical devices which stimulate the heart to beat appropriately. Currently, pacemakers do not operate at optimal conditions, resulting in limited battery life and generic functional settings for patients. Pacemaker batteries have an average life of 5-6 years, leading to frequent necessary replacements and increased mortality from the risks of surgery. Further, the ‘one size fits all’ approach to current pacemaker settings leads to inefficient pacing that can result in inadequate symptom relief and, in some cases, can damage heart muscle by over-pacing the ventricles. We propose to optimize pacemakers through developing novel software tools that generate patient-specific pacemaker device settings, resulting in (1) enhanced battery life, (2) decreased/eliminated replacement surgeries, (3) increased symptom relief, and (4) optimal pacing rates. We estimate this has the potential to save £32m for the NHS in the UK. The project arises from the results obtained in the first phase of the ERC Advanced Grant AdG-246967 VERIWARE (http://www.veriware.org/), which is concerned with sensor-enabled software-controlled devices (so called ‘everyware’), aiming to develop quantitative modelling, verification and synthesis techniques and tools to support the design and validation of their embedded software. The key innovation is the idea of automated synthesis of optimal rates adapted to patient data. While model-based design and validation are employed in the development of pacemakers, parameter settings are largely pre-defined and not changed upon implantation. Our proposal has the potential to revolutionise the design and manufacture of pacemakers.

Keywords: 246967
Mimimally invasive retrograde targeting of aCAR lentiviral vector to non-human primate motor neurons (RTLVNHP)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: United Kingdom,France
Call:  (ERC-2013-PoC, 2013)
Start date: 2014-04-01
End date: 2015-03-31
Duration (months): 12.0
Total project cost (EUR): 164776.8
EU funding (EUR): 149525.98
Participants: 2
Project status: CLOSED

Lentiviral vectors pseudotyped with the rabies-G envelope have been used for the delivery of therapeutic transgenes via the peripheral intamuscular route, increasing lifespan and reducing neuromuscular deficits in mouse models of both amyotrophic lateral sclerosis and spinal muscular atrophy. Despite these successes clinical translation of gene therapy for ALS with these and other vectors with retrograde transport such as AAV2 has been hampered as a result of limitations experienced with gene transfer in non-human primates (NHPs). In order to overcome these limitations, and to design a safe, efficient and a minimally invasive therapeutic strategy, we have developed as part of the ERC Advanced investigator’s grant: IRLVGTMND, a novel new generation of surface engineered lentiviral vectors with tropism to motor neurons (MNs) via the neuromuscular junction (NMJ). These vectors are targeted with antibodies against NMJ presynaptic terminal receptors, such as the CAR (coxsackievirus and adenovirus receptor). We found that these vectors can recognise, bind and enter target cells with high specificity determined by the antibody incorporated on their surface. They have specificity for MNs and have retrograde transport as demonstrated in vitro in compartmentalised primary motor cultures and in vivo upon intramuscular (i.m.) delivery in leg muscles leading to transduction of lumbar spinal cord MNs. All data to date indicate that the targeted lentiviral vectors we have constructed have superior transduction and specificity for MNs than previously used lentiviral vectors, making them thus good candidates for minimally invasive neuroprotective gene therapy of ALS. We therefore with this PoC grant want to investigate the transduction of NHP MNs via i.m. injections. We aim to have an indication within 12 months whether these vectors can achieve sufficient transduction in this model which will open up the way for their preclinical development, clinical testing and commercialisa

Keywords: irlvgtmnd 233147
Commercialization and Dissemination of Innovative Isotopic Labelling Solutions and Services for the NMR Studies of Important Protein Targets (NMR-BIO)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: France
Call:  (ERC-2013-PoC, 2013)
Start date: 2014-03-01
End date: 2015-02-28
Duration (months): 12.0
Total project cost (EUR): 149839.0
EU funding (EUR): 149839.0
Participants: 1
Project status: CLOSED

With the strong support of the ERC Starting Grant, our team has succeeded in developing a range of labelled precursors and kits for simple and efficient labelling of large proteins (up to 1 MDa size) for Nuclear Magnetic Resonance (NMR) studies. With such cutting-edge technologies in hand, the PI’s team is able to investigate the mechanism of action of large and functional cellular machines using NMR spectroscopy. In addition, these cutting-edge labelling technologies provide exclusive dynamic and structural informations about interactions with physiological partners, leading to new interesting opportunities for pharmaceutical and biotechnological applications. This ERC-POC project aims at making available to both public and private researchers a unique set of "user-friendly" labelling kits for NMR studies, as well as our know how and expertise in labelling techniques and NMR spectroscopy, through a dual offer (innovative products and high value-added services) to meet the strong demand expressed in this domain. Proposed services will include the tailor-made production of labelled proteins and the NMR analysis of those proteins in the context of large interactions. The ERC-POC project should lead to the creation of a spin-off company, which will undertake the valorisation of these patented innovations, but also integrate the major achievements of the ERC Starting Grant program. Each major research discovery is developed (and will continue to be developed) as a potential market product or service using technology transfer grants provided by host institution, in order to feed the company pipeline for dissemination and commercialization. This project will thus ensure all the needed steps to succeed in this initiative by 1) allowing to communicate around the products and services, 2) conduct an essential market survey to define the company’s offer and 3) recruit the dedicated human resources to achieve the creation of the NMR-Bio company.

Keywords: 260887