Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Lee-Yang theory of phase transitions in interacting quantum many-body systems (QuLeeYang)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Finland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-04-01
End date: 2022-03-31
Duration (months): 24.0
Total project cost (EUR): 190680.96
EU funding (EUR): 190680.96
Participants: 1
Project status: CLOSED

Over the last years, investigations of Lee-Yang zeros – complex zeros of the partition function for systems of finite size – have become an indispensable theoretical tool in equilibrium statistical physics with diverse applications, ranging from protein folding and percolation to complex networks and magnetism. In the thermodynamic limit, the Lee-Yang zeros approach the real value of the control parameter for which a phase transition occurs. Despite these developments, surprisingly little attention has so far been devoted to applications of Lee-Yang theory beyond classical equilibrium systems. One reason may be that Lee-Yang zeros (being complex values of physical quantities) for years were seen as a purely theoretical concept with little relevance to experiments. However, this view has recently been contested by several experiments, in which Lee-Yang zeros have been determined. A novel cumulant method allows for the determination of Lee-Yang zeros from measurements of fluctuating observables, thus offering a completely new perspective on phase transitions in interacting many-body systems. Here, building on this cumulant method, I propose to formulate a unifying theory of phase transitions in interacting quantum many-body systems, including space-time, dynamical, and quantum phase transitions, from the perspective of Lee-Yang zeros. I will connect this theoretical framework to large-deviation statistics, fluctuation relations, and many-body entanglement in non-classical systems. Furthermore, I will devise experimental schemes to test my predictions and, in particular, investigate quantum phase transitions in engineered quantum devices. Fulfilling these objectives will expand the field far beyond its current state-of-the-art and potentially result in major scientific breakthroughs with important implications for other research fields, such as quantum information processing and quantum thermodynamics.

Keywords: lee yang zeros,non equilibrium phase transitions,quantum phase transitions,large deviation statistics
COld sprayed COating on COmposite (CO3)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: France,France,France,Luxembourg
Call: Cold Spray of metallic coatings on polymer and composite materials [SAT] (H2020-CS2-CFP08-2018-01, 2018)
Start date: 2019-03-01
End date: 2021-08-31
Duration (months): 30.0
Total project cost (EUR): 699992.5
EU funding (EUR): 699992.5
Participants: 6
Project status: CLOSED

Thermal spray technologies progressed from a rudimentary process difficult to control towards an increasingly precise one. Dedicated tool and associated process can now be tailored according to properties of both deposited material and coatings. Limitation of coating types seems to be overcome for some materials thanks to the newest thermal spray process Cold Spray (CS). Feasibility, optimization and qualification investigation of CS is still required to enable this innovative process to comply with prospective aircraft applications. The CO3 project will target the full implementation of the CS process development up to its first demonstration through the metallization of a front landing gear fairing. CO3 project consortium gathered 5 European Partners with required skills, complementary expertise and capabilities. They will tackle the ambitious improvement objectives expected such as to improve: thermal spray metallization demonstration of non-metallic substrates, deposition efficiency and microstructure characteristics, optimal processing conditions and its effect of on coating characteristics, robotized manufacturing capacity, CS process demonstrator and awareness raising towards other areas of aircraft applications. To achieve such results, CO3 project will implement three distinctive strategies to enhance the CS operational and technological conditions and enable better performances to limit/avoid substrate erosion: Low pressure CS, Mixed metal-polymer powders, Metal charged supercritical Nitrogen for subsurface incrustation of metallic particles for thermoplastic base materials prior to CS, Intermediate CS layer made of low erosive metallic particles and a final aluminum top coat CS layer, Interlayer integration during substrate manufacturing process. CO3 achievements will directly contribute to the improved CS non-metallic substrate metallization process qualification and related technology guidelines definition for future aerospace industry benefit.

Keywords: cold gas dynamic spray,metallic coatings,polymer,carbon fiber composite,supercritical nitrogen,conductive coating
Theoretical beamlines to time-resolved ultrafast Auger electron spectroscopy (TR-AES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-06-01
End date: 2023-05-31
Duration (months): 24.0
Total project cost (EUR): 219312.0
EU funding (EUR): 219312.0
Participants: 1
Project status: SIGNED

A novel application of a multicentric linear combination of atomic orbitals (LCAO) B-spline method to the accurate evaluation of resonant and non-resonant (time-resolved) Auger electron spectroscopy (AES) is proposed. The approach will combine equation-of-motion Coupled Cluster (EOM-CC) as well as complete active space self-consistent field (CASSCF) methods for the treatment of the bound states with the LCAO B-spline methodology to account for the outgoing electron and, thus, accurately address AES. Time-resolved Auger spectra will be simulated by incorporating our methodology with state-of-the-art nuclear dynamics approaches, such as multiconfiguration time-dependent Hartree method for the wave packet propagation and surface-hopping mixed quantum-classical dynamics. The development of cutting-edge theoretical and simulation tools for time-resolved ultrafast AES, presented in this proposal, will leverage the current and future experimental efforts on time-resolved AES in many laboratories and at large-scale facilities around the world, such as the European XFEL.

Keywords: quantum chemistry,coupled cluster theory,photoionization,x ray absorption,x ray ionization,b spline continuum wave function
Reducing the impact of environmental disasters: AI-based assistant for fronline emergency management (IRIS)

Framework: Horizon 2020 — Societal Challenges
Action type: SME instrument
Countries involved: Spain
Call: H2020-EIC Accelerator pilot –SME Instrument - Green Deal (H2020-EIC-SMEInst-2018-2020-4, 2020)
Start date: 2020-12-01
End date: 2023-06-30
Duration (months): 31.0
Total project cost (EUR): 3465000.0
EU funding (EUR): 2425500.0
Participants: 1
Project status: SIGNED

Imagine a first responder answering the call to a wildfire or to a massive flooding, where there may lives and properties at stake. The information they need to fulfill the mission is crucial. Also, the number of teams and emergency services deployed in these situations is very large. Commanders in the field need to have a precise understanding of what is happening, and they have to coordinate perfectly with all the teams available In addition, Emergency Services are heavily investing in technology to improve their operations (drones, cameras, sensors, wearables…), leading to information overload in the field. UNBLUR believes Artificial Intelligence is one viable option that can potentially prevent massive loss of lives and properties while at the same time make emergency response easy and efficient. Our innovation IRIS is a state-of-the-art human-like reasoning system designed to assist first responders in synthesizing high-level data while at the scene of an emergency. IRIS learns, analyzes, reasons, predicts, collaborates, and provides data fusion to provide direction for first responders on the scene. It provides situational awareness during an incident, connecting first responders across different agencies with vital information right at their fingertips. IRIS purpose is to aid responders in taking all of the pertinent data related to an incident and making quicker decisions. In turn, this not only helps first responders save lives but also keeps them better protected. IRIS is the first IT web tool designed with and for Incident Commanders in the field. The technology is being co-designed and tested by 10 Emergency Services in Europe and is starting to generate interest among heavyweights in the industry, such as Airbus. A quicker allocation of teams to a wildfire thanks to IRIS would reduce the number of uncontrolled wildfires by 9%. This would mean reducing the burn of an average of 107,920 hectares of forest per year and savings of € 899,3 million.

Keywords: emergency services,public safety,first responders,digital assistant,incident command,artificial intelligence
DevOps for Complex Cyber-physical Systems (COSMOS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Germany,Germany,Switzerland,Czechia,Netherlands,Luxembourg,Portugal,Portugal,United Kingdom
Call: Software Technologies (H2020-ICT-2020-1, 2020)
Start date: 2021-01-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 4998571.25
EU funding (EUR): 4998571.25
Participants: 12
Project status: SIGNED

Much of the increasing complexity of ICT systems is being driven by the more distributed and heterogeneous nature of these systems, with Cyber Physical Systems accounting for an increasing portion of Software Ecosystems. This basic premise underpins the COSMOS proposal which focuses on blending best practices DevOps solutions with the development processes used in the CPS context: this will enable the CPS world to deliver software more rapidly and result in more secure and trustworthy systems. COSMOS brings together a balanced consortium of big industry, SMEs and academics which will develop enhanced DevOps pipelines which target development of CPS software. These pipelines will integrate more sophisticated validation and verification (V&V) which will comprise of a mix of static code analysis correlated with issues and bug reports, automated test case generation, runtime verification, Hardware in the Loop (HiL) testing and feedback from field devices. Approaches based on Machine Learning, model based testing and search based test generation will be employed. Techniques to prioritize and schedule testing to maximize efficacy of the testing process and to minimize security threats will also be developed. COSMOS will leverage existing prototype technologies developed by the partners supporting enhancing them throughout the project. The COSMOS CPS pipelines will be validated against 5 use cases provided by industrial partners representing healthcare, avionics, automotive, utility and railway sectors. These will act as reference use cases when promoting the technology amongst Open Source and standardization communities. For the former a specific community building activity will be performed to stimulate engagement with Open Source; for the latter, the standards experience of the coordinator and partners will be employed to promote COSMOS technologies within heavily regulated sectors where there is an increasing need for well-defined software V&V solutions.

Keywords: devops,cyber physical systems
Visible Light Communication (VLC) application for mobile devices as control access, validation, master key or secure payment solution. (LIGHTKEY)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2015-06-01
End date: 2015-08-31
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

LightBee S.L. innovated the solution which uses LEDs installed in any transmitter to transmit binary codes by means of light modulation to an optical receiver which later decodes the light flash. The light is transmitted at a very high speed to avoid the possibility to distinguish values by video camera or human eye. It allows auto check-in and access control to private property or office only with the mobile information. The LightKey product based on Visible Light Communication (VLC) is very powerful and at the same time low cost technology, that can be adapted to grant safe access permission by using merely mobile device with the performance similar to intrusive and expensive NFC and RFID technologies. The set consists of Control Unit, Optical Receiver, mobile application and uses standard electronic lock. As there is an increasingly urgent need for authenticated entrance and the universal integration of mobile devices in our society is observed, LightKey has the chance to meet the broad range of innovative customers of the Access Control Market: private companies and independent users (hotels, complexes, condominiums, car makers) and public customers where security is a top priority (hospitals, banks, administration). When considering further proliferation of solid-state lighting (SSL), LED importance, the fact that nowadays technologies: NFC, Bluetooth, WIFI are subject of security problems related to data transmissions and moreover the increasing crime rate related to domestic burglary worldwide, VLC can become the most promising technology in terms of commercial viability. A full assessment of customer needs and the elaboration of a realistic business plan with in depth market feasibility study is the main objective of present Phase 1. After positive output following tasks will be addressed during Phase 2: analysis of remote communication, optical receiver optimization, integration with other technologies, certification, cloud service development.

Keywords: visible light communication,led technology,access control system,safe communication,encrypted communication
Mechanisms of recovery after severe spinal cord injury (HOW2WALKAGAIN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Switzerland
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-07-01
End date: 2021-06-30
Duration (months): 60.0
Total project cost (EUR): 1998715.0
EU funding (EUR): 1998715.0
Participants: 1
Project status: CLOSED

Severe spinal cord injury leads to a range of disabilities, including permanent motor impairments that seriously diminish the patients’ quality of life. In the framework of an ERC Starting Grant, my team and I developed a pragmatic therapy that restored supraspinal control of leg movement after complete paralysis in rats. However, the mechanisms underlying the effects of this intervention remain unknown. This fundamental knowledge is pivotal to operate a disruptive conversion from our empirical approach to an evidence-based strategy with clinical perspectives. Our therapy, termed neuroprosthetic rehabilitation, acts over two time windows. Immediately, electrical and chemical spinal cord stimulations mediate motor control of the paralysed hindlimbs. In the long term, will-powered training regimens enabled by electrochemical stimulation and robotic assistance promote neuroplasticity of residual connections—an extensive rewiring that reestablishes voluntary movement. Here, we propose to identify the circuit-level remodelling, computational principles, and molecular cues that govern the immediate and long-term recovery of motor functions. To address this knowledge gap, we will use our unique neuroprosthetic platform and next-generation experimental techniques for longitudinal assessment of neuroplasticity and function in freely behaving mice. These techniques combine optogenetics, circuit-level inactivation techniques, unconstrained chronic calcium imaging, virus-mediated tract-tracing and genetic manipulations. Our strategy consists of deploying a judicious association of these experimental techniques to establish causality between the reorganisation of the motor circuitry and functional recovery. This project will fertilize frontier research with new knowledge and ideas, ultimately accelerating clinical implementation of safer and more efficacious therapies to improve the quality of life for spinal cord injured individuals.

Keywords: neurorehabilitation,neuromodulation,robotics,locomotion,neuroplasticity,bdnf,spinal cord injury,mice
New combined solution to harness wave energy full renewable potential for sustainable electricity and fresh water production (W2EW)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Italy,Finland,Netherlands,Denmark
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2018)
Start date: 2019-01-01
End date: 2023-10-31
Duration (months): 58.0
Total project cost (EUR): 5296090.0
EU funding (EUR): 3000000.0
Participants: 4
Project status: SIGNED

With 96.5% of all water on Earth being on the ocean, there is a theoretical ocean wave energy potential of 2000 GW of installed capacity, which could contribute to decarbonizing the energy system, expanding the water supply through desalination and creating a new industry with export opportunities worldwide. However, this opportunity remains underexplored due to remaining technological, market, environmental and social challenges. With wave energy still in the pre-commercial development stages, the EU setting a target of 337 GW of installed wave by 2050 and a direct EU economic impact of drought events in the past 30 years estimated at a minimum of € 100BN, there is a unique opportunity for strong industrial cooperation towards the deployment of solutions to address the twin challenges of energy and fresh water shortage. Leveraging on a strong consortium vision, expertise and technologies, the W2EW project aims to deliver a world beating and first of a kind wave powered technology solution – W2EW solution – to the market. The solution relies on the innovative integration of wave energy and water desalination technologies, to produce zero-emission electricity and fresh water. The main goal of this project is to integrate the partners technologies, demonstrate the combined solution, and build the market to pave the way for broad market roll-out. Thirty-three months after project start the consortium plans to roll out the W2EW solution on off grid small-scale energy and water production in islands and isolated coastal communities with up to 100,000 inhabitants, which corresponds to a potential market of 22Bn EUR for electricity and 6Bn EUR for freshwater. After 2025 we intend to extend the customer base of the W2EW solution to the large-scale utilities for production of renewable energy and/or water desalination, to be an alternative and/or to operate in synergy with offshore wind and solar PV.

Keywords: wave energy,wave power,decarbonising islands,desalination
Identification and characterization of novel essential regulators of acute myeloid leukemia (NovLeuReg)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-04-01
End date: 2018-09-02
Duration (months): 24.0
Total project cost (EUR): 212194.8
EU funding (EUR): 212194.8
Participants: 1
Project status: CLOSED

Acute myeloid leukemia is a hematopoietic malignancy characterized by the abnormal proliferation of immature myeloid cells. The implementation of high-throughput sequencing revealed that somatic mutations in various epigenetic regulators represent a frequent pathogenic phenomenon in leukemogenesis. This raised optimism for the development of new therapies in leukemia due to the reversible nature of epigenetic marks and amenability of chromatin-modifying enzymes to pharmacological inhibition. However, realization of this potential requires further research into epigenetic mechanisms governing the maintenance of leukemic cells. The overall goal of the proposed work is to characterize novel important epigenetic regulators in leukemic cells and to assess their potential as drug targets. Firstly, I plan to identify and study epigenetic regulators essential for leukemic cells deficient in TET2, an enzyme that hydroxylates methylated cytosines in DNA. This will be achieved by performing state-of-the-art shRNA screens in mouse Tet2-null leukemia models and by exploring the functions of the uncovered candidates using a range of cell biology, biochemistry, and functional genomics approaches. The second aim is to investigate the molecular functions of SETD5, a newly-uncovered epigenetic regulator of leukemic cells. This will be achieved by identifying its target genes and interacting partners in leukemic cells and by exploring the effects of its depletion on normal and cancer cells. The accomplishment of both research aims will provide new insights into epigenetic regulation of leukemic cells and highlight novel drug targets for future therapy development. The project will be supervised by Prof Kristian Helin, a world-leading expert in the field of epigenetics and cancer. Through this work, I aim to broaden my scientific expertise by acquiring numerous technical and transferable skills and to establish myself as an independent researcher in the field of cancer epigenetics.

Keywords: leukemia,hematopoiesis
A disruptive method to free physicians from Hospital Information Systems by generating fault free patient diagnostic documents in real-time using natural language (REALM)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Finland
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2015, 2015)
Start date: 2015-10-01
End date: 2016-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

A significant bottleneck in Europe’s health care model is that physicians are spending up to 30 % of their time operating complex Hospital Information Systems (HIS). The Diktamen-method totally frees the physician from HIS and revolutionizes any voice-to-text capabilities. All diagnostic data is expressed with natural language, while the error free diagnostic document is produced in real-time. Our pilot study showed that physicians treat 25 % + more patients per day with the Diktamen-method. According to our growth plan this is the equivalent of generating 13 888 new physicians inside EU-27 by the year 2020.

Keywords: diagnostic,patient,disruptive,hospital inofrmation system