Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Laboratory for Innovation in Opto-Mechanics (LIOM)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Coordination and support actions
Countries involved: Spain
Call: ERA Chairs (HORIZON-WIDERA-2022-TALENTS-01, 2022)
Start date: 2023-02-01
End date: 2028-07-31
Duration (months): 66.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Enabling large optical systems capable of resolving and measuring faint sources not accessible with current remote sensing instruments and detectors is the scientific overarching aim of LIOM by creating and sustain an excellent ERA Chairs optics and photonics' technology group of experimental physicists and astronomers, engineers, and technicians with an innovative optics and photonics technology environment. Under the leadership of the outstanding researcher and research manager Prof. Jeffrey Kuhn we aim to build a collaboration that will lead to the development of the next 50 years of astronomical telescopes - be they on the ground, space, or the moon. The main objective is to build new capacities at the IAC, Canary Islands, to develop new optical and tensegrity technologies to incorporate into the next generation of telescopes aimed at high-contrast imaging of exoplanets around very bright stars to enable the search for signs of life. We've called this an "ExoLife Finder (ELF)" telescope but this direct imaging technology is equally important, for example, for the commercial study of man-made satellites in the terrestrial to CISLunar environments. LIOM optics technologies will also have important social benefits, for example the new ultra-thin and light mirrors created during this program would be key components of Earth-orbiting optically-linked satellites that will constitute the next phase of the "world-wide web" - the space-based global optical internet. With the implementation of this ERA Chairs project, the IAC will enlarge its outstanding flagship in Europe and beyond, specifically in the field of optical remote sensing technologies for astronomical purposes, exemplifying not only the achievements in R&I and its capacity development or competitiveness, but also the creation of synergies with leading American and European institutions.

Keywords: mirrors,optical communication,telescopes,photonics,biomimetics,exoplanets,exolife,wavefront control,coronographic,direct imaging,nulling interferometry
Integrated GermaNIum quanTum tEchnology (IGNITE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Research and Innovation actions
Countries involved: Netherlands,Italy,Spain,Hungary,Belgium,Denmark,Austria,Germany
Call: Investing in new emerging quantum computing technologies (RIA) (HORIZON-CL4-2021-DIGITAL-EMERGING-01, 2021)
Start date: 2022-07-01
End date: 2025-12-31
Duration (months): 42.0
Total project cost (EUR): 4996815.75
EU funding (EUR): 4996815.75
Participants: 10
Project status: SIGNED

Spin qubits in germanium have resulted in the most advanced semiconductor quantum processor. Within five years of development, germanium qubits are established as a highly promising candidate for large-scale quantum computing. Germanium is a standard semiconductor manufacturing material and germanium qubits are the only semiconductor qubits that are defined exclusively by transistor-based structures and has enabled to demonstrate a universal quantum gate set [Hen20]. This is highly promising for scalability and adoption by leading semiconductor technology. A revolution in the growth of strained germanium sparked a remarkable development which led to the first germanium quantum dot, germanium qubit, two-qubit logic in germanium, four-qubit logic in a two-dimensional array, and operation of a 16 quantum dot array. This program brings together all the partners that enabled these developments to form a consortium with leading scientists and industry, to fulfil the promise of germanium quantum technology, by scaling the number of qubits, by designing architectures allowing to advance beyond 1000s of qubits, and by experimentally implementing a computational task that can provide a quantum advantage. The key objective of Integrated Germanium Quantum Technology (IGNITE) is thus to demonstrate that germanium defines a compelling platform for quantum computation with excellent qubits operating in a scalable network. We therefore focus on four key components to demonstrate its success:

Keywords: germanium qubits,semiconductor quantum technology,quantum dots
Development of an enhanced laser beam technology based on a new optical system for industrial laser processing applications. (inPhocal)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-01-01
End date: 2024-12-31
Duration (months): 24.0
Total project cost (EUR): 3586578.75
EU funding (EUR): 2499999.0
Participants: 1
Project status: CLOSED

Although inkjet marking systems are widely used for marking the products, factors such as high running costs and low quality of marks are preventing their 100% adoption. The toxicity of inks in addition makes them harmful for the land & water ecosystems. Further, these systems spill tiny droplets of ink while printing, resulting in lower resolution as compared to laser printed coding. However, conventional laser systems cannot solve all the inkjet marking drawbacks, mainly due to their lower marking speed. InPhocal has developed the world’s first optical system that can be integrated with laser marking systems to increase the focus range of the original laser beam up to 400 times. The laser marking machine integrated with InPhocal technology will provide advantages such as high marking resolution, higher production rate and printability on curved surfaces. In the EIC project, InPhocal team plans to miniaturize the device, conduct pilot trials followed by business development.

Keywords: lasers,photonics,production efficiency
Global Methane Politics (METH-POL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 2499924.0
EU funding (EUR): 2499924.0
Participants: 1
Project status: SIGNED

The ambition of the Global Methane Politics project is to produce a pioneering body of research that simultaneously establishes the distinctiveness of methane politics, investigates and demonstrates the most significant political obstacles to methane emissions reduction, and has transformative impacts on global methane and climate policies and practices. Research on methane politics is urgently needed because 1) methane is the second largest contributor to anthropogenic climate change; 2) reducing methane emissions provides one of the most obvious routes to short-term climate mitigation, including limiting warming to near 1.5°C; 3) methane has become widely recognised as an important international policy concern since the launch of the Global Methane Pledge (GMP) in 2021; and yet 4), very little research has so far been conducted on methane policy, regulation or politics in practice - which is a critical shortcoming if the GMP target of a 30% reduction in emissions by 2030 is to be more seriously pursued. METH-POL will be novel, impactful and timely. Guided principally by research in political ecology, it will test a series of original hypotheses about the specificity of methane politics, the political barriers to methane emissions reduction, and the implications thereof for research, policy and practice. It will produce the first dedicated body of cross-sectoral, cross-national, multi-scalar, trans-disciplinary and comparatively informed evidence on methane politics. It will involve research on 16 countries, on the global North and global South, on every continent, on the top five methane emitting countries, on the major methane emissions sectors, and on a wide range of methane governance initiatives, institutions and techniques. And it will also involve extensive knowledge exchange with scientific, policy and practitioner communities. A 5-year project, METH-POL will run from 2026 to 2030 – the critical years if the GMP 30-30 target is to be achieved.

Keywords: methane,political ecology
Establishing a Network of Permanent Observatories for Mosquitoes and Mosquito-Borne Diseases in East and Southern Africa (VectorGrid-Africa) (VectorGrid-Africa)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Global Health EDCTP3
Action type: Research and Innovation actions
Partnership: EDCTP3 (JU-JTI)
Countries involved: United Kingdom,Tanzania, United Republic of,Madagascar,South Africa,Mozambique,Kenya
Call: New tools, technologies and approaches for vector control in sub-Saharan Africa (HORIZON-JU-GH-EDCTP3-2024-01-two-stage, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 6144373.98
EU funding (EUR): 6144095.73
Participants: 10
Project status: SIGNED

The fight against mosquito-borne diseases in sub-Saharan Africa is significantly hindered by the absence of comprehensive, long-term, and high-quality datasets. This limitation hinders our understanding of disease transmission dynamics, the effects of climate change, the consequences of anthropogenic factors such as deforestation and urbanization, and the impacts of vector control interventions. Although the WHO advocates for surveillance as a core intervention against vector-borne diseases, most low-income countries lack the financial and technical capacity to implement this on a large scale. Furthermore, there are no systematic efforts to collect such critical data in Africa, even as risks from climate and land use changes increase. We therefore propose to establish a networked observatory for systematic and long-term collection, analysis and dissemination of high-quality data on mosquitoes and mosquito-borne diseases in Africa, starting with five countries in the east & southern Africa region. The observatory will comprise geographically dispersed data collection nodes, reflecting spatial variations in climate, disease epidemiology, and socio-economic conditions, and will be owned and managed locally by African partners to enhance sustainability. To maximize value, the observatory will cover multiple mosquito-borne diseases, collecting standardized data on entomological metrics such as vector densities, species diversity, seasonal phenology, host preferences, transmitted pathogens, and genomic variations, alongside critical climatic, anthropogenic, and other environmental factors. We will build in-country capacity to perform all the entomological and genomic assays locally without having to ship samples abroad; including capacity to analyze, interpret and use the data. We will also gather summaries of health metrics from local facilities and collaborate with partners to include One Health indicators, aligning with global health security priorities.

Keywords: surveillance,infectious diseases,climate,preparedness,global health security,vector control
New Horizons in Glass Structure Prediction and Mechanics (NewGLASS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Denmark
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1996935.0
EU funding (EUR): 1996935.0
Participants: 1
Project status: SIGNED

Oxide glasses are one of the most important material families owing to their unique features, such as transparency, tunable properties, and formability. Emerging solutions to major global challenges related to energy, health, and electronics require new scientific breakthroughs in glass chemistry, mechanics, and processing. The realization of these goals is severely restricted by the main drawback of glass, namely high brittleness. Furthermore, new glass compositions are today developed through time-consuming trial-and-error experimentation due to their inherent non-equilibrium nature and disordered structure. A major task is therefore to initiate a paradigm shift within the field of glass science and technology, going from empirical to model-based approaches for the design of new glass compositions and microstructures with improved fracture resistance. This requires the development of computational approaches, from ab initio calculations to artificial intelligence, to integrate structural descriptors and glass chemistry with advanced processing and mechanical properties into holistic tools. NewGLASS challenges the current glass design strategies in order to create such tools. For this purpose, an interdisciplinary approach is proposed, in which structural descriptors at the short- and medium-range length scales are first identified and quantified based on emergent statistical mechanics and persistent homology techniques. Guided by these results, high-throughput simulations at various length scales are combined with machine learning algorithms to design novel glass compositions, tailored deformation mechanisms, and 3D-printed microstructures to achieve superior fracture resistance. By having experiments and modelling complement and advance each other reciprocally, NewGLASS will find order in disorder and provide the scientific breakthroughs for the accelerated design of glasses with outstanding mechanical performance, thus opening up for many new applications.

Keywords: glasses,mechanical properties,topological data analysis,statistical mechanics,machine learning,molecular dynamics simulations,3d printing
e-Intervention Enhancing Mental Health in Adolescents (IMPROVA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Staying Healthy in a rapidly changing society
Action type: Research and Innovation actions
Countries involved: Spain,France,Netherlands,Romania,Sweden,Czechia,Germany
Call: Boosting mental health in Europe in times of change (HORIZON-HLTH-2022-STAYHLTH-01-two-stage, 2022)
Start date: 2023-04-01
End date: 2027-03-31
Duration (months): 48.0
Total project cost (EUR): 6998198.75
EU funding (EUR): 6998198.75
Participants: 14
Project status: SIGNED

The e-Intervention Enhancing Mental Health in Adolescents project, IMPROVA, will co-design, pilot, evaluate, and facilitate the upscaling of a modular eHealth intervention platform that aims to improve mental health and well-being, early detect mental health problems and prevent common mental disorders in adolescents. The IMPROVA consortium includes an international and inter-disciplinary group of researchers and practitioners from health, educational and social sciences in addition to computer scientists, a teacher association and policymakers. The IMPROVA online platform will be co-created with stakeholder groups, including adolescents, parents, teachers, school health professionals and policymakers based on materials already designed and tested in more than 20 projects carried out by the consortium members. The platform will include components for adolescents, parents, teachers, and school health professionals in complementary and synergistic modules. After a series of pilot testing sessions, IMPROVA will be implemented by conducting a randomized Stepped Wedge Trial Design (SWTD) in secondary education schools randomly selected in four countries (France, Germany, Romania and Spain), including 12,800 adolescents. Effectiveness, cost-effectiveness and cost-benefit will be calculated. Using implementation science methodology, IMPROVA will co-design with policymakers and stakeholders transferable evidence-based practices, methodologies and guidance for upscaling of the IMPROVA platform. IMPROVA aims to provide stakeholders and policy makers with an evidence-based, innovative, large-scale, comprehensive intervention, and a scale-up plan to promote mental health and prevent mental disorders in adolescents; empower adolescents and families to make better decisions regarding their mental health; and provide schools and the community with tools to achieve a society with better mental health and lower stigma.

Keywords: mental health,education,epidemiology,psychology,psychiatry,prevention,health promotion,adolescence,lifestyle
Integration of Advanced Experiments, Imaging and Computation for Synergistic Structure-Performance Design of Powders and Materials in Additive Manufacturing (SynAM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Poland,Kosovo,Türkiye,Ghana,Malaysia,United Kingdom
Call: MSCA Staff Exchanges 2022 (HORIZON-MSCA-2022-SE-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 636771.43
EU funding (EUR): 565800.0
Participants: 9
Project status: SIGNED

The proposed project aims to collaboratively integrate modern data system, experiments, imaging, machine learning and predictive engineering-physical modelling for additive manufacturing (AM) and materials developments. Through focused knowledge transfer, close interdisciplinary teamwork and fusion of the academic-industrial research/resource, the team will jointly establish a systematic data system of the structure, properties, defects and distortions in AM of a range of materials at different scales and use the data for materials development and AM process optimisation. The effect of AM processing and surface treatments on the surface integrity and functional properties (e.g. corrosion resistance) of AM materials is to be systematically established. The project will develop practical imaging and processing algorithms for the analysis, design, and joint quality control for the input materials in AM, including powder production. Engineering and key physical modelling is to be integrated with machine learning for predictive composition and structure design for optimum synergy between printability, properties and performances. Materials development balancing printability and structure properties will be focused on advanced materials requiring critical phase control in AM, including duplex stainless steels, amorphous glass metals and Mg. The advanced data and materials will serve as a pivoting platform for future research and innovation in AM, speeding up material development within the full product development life cycle. Through focused intersectoral and international knowledge exchange and joint R&I within a multidisciplinary team, the project will contribute to the continuous practical applications of Industry 4.0 technologies and development for industry5.0 in AM, further enhancing the design freedom in composition and structure for application-specific products, and accelerating the researcher development with lasting impact in the EU and beyond.

Keywords: additive manufacturing
Thiophenylalanine: A novel handle for peptide synthesis, stapling and protein labelling. (ThioShowcase)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-11-01
End date: 2026-10-31
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

Chemoselective functionalisation of peptides and bio-conjugation of proteins has led to great advances in the synthesis of clinically relevant biomolecules and our understanding of cellular processes. Thiophenylalanine represents an interesting handle owing to the increased acidity of the aryl thiol which would mean a higher percentage of reactive thiolate would persist even at physiological pH, allowing chemoselective reactions to be performed. Despite the interesting qualities of the residue, there is a notable gap in its use in peptide and protein chemistry which can be attributed to the difficult and harsh conditions required involved in the synthesis, often incompatible with common protecting groups. Herein, we exploit a mild, palladium catalysed method to obtain Fmoc-SPhe(Trt) in one step from commercially available reagents to fully explore the possibilities of incorporating the building block into peptide and protein synthesis. Namely, we will demonstrate the use of SPhe 1) as a chemoselective method for peptide stapling, 2) to perform on-resin selective disulfide formation and attempt a regioselective one-pot double disulfide formation of a novel antimicrobial peptide, 3) as a method for discretely labelling protein residues through affinity-binding proximal transfer and 4) in the form of other aryl thiol building blocks to expand the scope of this work. The development of a novel handle for bioconjugation will have an immense impact on the field of chemical biology and provide a tool for peptide analogue synthesis and elucidation of cellular processes.

Keywords: peptide methodology,peptide stapling,organic chemistry,protein labelling