Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A plug and play PHOTOnics based bioSENSing platform for salmon pathogen detection (PHOTO-SENS)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Germany,Germany,Switzerland,Netherlands,Netherlands
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2020)
Start date: 2020-12-01
End date: 2024-05-31
Duration (months): 42.0
Total project cost (EUR): 4040582.94
EU funding (EUR): 2997497.24
Participants: 5
Project status: SIGNED

The UN's 2030 Agenda, adopted by world leaders in 2015, represents the new global sustainable development framework and sets 17 Sustainable Development Goals (SDGs). Foremost is the Zero Hunger SDG, which seeks to end hunger and malnutrition, and ensure access to safe, nutritious, and sufficient food. One of the most productive and efficient sources remains aquaculture, which is the process of rearing, breeding, and harvesting of aquatic species, in controlled aquatic environments, like the oceans, lakes, rivers, ponds, streams and purpose built Recirculating Aquaculture systems (RAS). According to the UN’s Food and Agriculture Organization (FAO), aquaculture is growing faster than any other major food production sector, with 50% of all sea food consumed is obtained by aquaculture. We are currently standing at a critical juncture to maintain healthy aquaculture conditions. To do so we need to continuously monitor the living environments of the fish and apply cutting edge bio-sensing to safeguard these fish farms and therefore our food security. The current consortium brings together the latest in biosensor technology, scaling up procedures, and aquaculture expertise, to safeguard our food security in the present and future years. By becoming an aquaculture pathogen testing hub and bringing to market a working diagnostic platform monitoring salmon pathogens, the consortium [Surfix (NL), Phix (NL), TunaTech (DE), CSEM (CH), and LRE Medical (DE)] aims to provide a long-term solution to ensure our collective food security. This project will build upon the BIOCDx project (ID: 732309) which successfully delivered a working prototype, however, due to lack of scalability, the overall costs of the biosensor remained very high (~€500/chip). Thus, the principal aim of PHOTO–SENS is to investigate scalable production of this technology (to reduce the costs 10 fold; €50/chip), and validation with an end–user in the aquaculture market.

Keywords: aquaculture,food security,biosensor,miniaturized,microfluidics,amzi,salmon,pathogen detection,high volume manufacture,scalability,photonics integrated chips
Human Cooperation to Protect the Global Commons (HUCO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Germany
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-08-01
End date: 2021-01-31
Duration (months): 66.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: CLOSED

The objectives of this research are to reveal the nature of large-scale human cooperation and to develop strategies for the protection of our global environment. Human activities are now the major driver of change in the biosphere, including the climate, the water cycle, and the distribution of species and biodiversity – with adverse effects that range from the local to the global scale. Since there is no world government that can enforce the protection of the global commons we have to rely on voluntary cooperation by sovereign actors. Previous findings from various disciplines have taught us important lessons about the nature of human cooperation. However, these literatures have almost exclusively focused on local or regional cooperation problems and their findings cannot be readily transferred to the international level. The research proposed here will fill this crucial gap. The methodological approach is genuinely interdisciplinary. In particular, the project will use and combine theoretical, experimental, evolutionary, and empirical methods. The interdisciplinary research team will start by analyzing case studies of international cooperation (or lack thereof). In an iterative process, the case-specific results will be explored in a rigorous context-free analysis using theoretical modeling, experiments, and simulations. With this, the project will: systematically analyze human cooperation from the local to the global scale and the differences between those scales; investigate which institutional arrangements enhance or prevent cooperative behavior at the global level; investigate whether individuals and groups are able to choose the right institutions and which factors determine their choice; synthesize the results to derive theoretical and practical insights about human cooperation and develop effective strategies for the management of the global commons; bring forward the integration of concepts and methods across disciplines for the study of human cooperation.

Keywords: human cooperation,global public goods,international environmental agreements
Discovery of breast cancer aggressiveness markers using topo-proteomics mapping (PROTEOMICAN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Israel
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-07-01
End date: 2021-06-30
Duration (months): 72.0
Total project cost (EUR): 1699261.0
EU funding (EUR): 1699260.75
Participants: 1
Project status: CLOSED

In the proposed research we will explore the functional proteomic diversity of histologically-defined regions within human breast tumors, aiming to identify novel protein biomarkers of tumor aggressiveness. Once identified, these proteins will serve as potent diagnostic markers and therapeutic targets. Towards this aim we will perform genome-scale proteomic profiling on tumor regions displaying diverse histopathology. This will be followed by functional investigation of these cancer cell sub-populations to determine their tumorigenic potential, and search for microparticle-based proteomic biomarkers from serum samples towards identification of cancer aggressiveness in blood tests. Analysis of the proteomic diversity holds a promise to reveal yet unidentified regulators of the tumorigenic phenotype as quantitative protein profiling is expected to most faithfully predict cellular phenotypes. This will be accomplished using the 'super-SILAC' technology, which I developed during my post-doctoral research. Using this technology, we identified over 12,000 proteins in formalin-fixed paraffin embedded breast cancer tumors. In the current project we will take one large step further, namely, microdissect and analyze selected regions in breast tumors based on local histopathological characteristics, such as the expression of known markers, cancer cell density, the vicinity to blood vessels and to the tumor invasive front. This "topological map" of the proteome will be followed by functional in vitro and in vivo studies, directly probing the aggressiveness of these cell populations, manifested by an accelerated proliferation and invasive/metastatic capacity. Finally, proteins associated with tumor aggressiveness will serve as blood-based biomarkers for predicting the tumorigenic phenotype using non-invasive tests. This work will set the basis for quantitative probing of tumor heterogeneity, which is crucial for accurate diagnosis and effective therapy.

Keywords: biomarker discovery
Climate ReOrganizations at Synoptic Scale as Recorded in the Offshore Archives of the Dead Sea (CROSSROADS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 264669.12
EU funding (EUR): 264669.12
Participants: 2
Project status: SIGNED

Water availability in the Mediterranean basin is projected to decrease in the future in the 6th IPCC report. It is largely influenced by wintertime synoptic atmospheric circulations, as the westerlies play a crucial role in the distribution of both rainfall and heat. However, to date, climate models have lacked the accuracy to predict the evolution of atmospheric circulations, making water availability projections uncertain and thus hampering adaptation strategies by policy makers. The Holocene epoch has been extensively studied to refine our understanding of climate and test the efficiency of climate models and proxies. And yet, mismatches among proxies and models leave the issue of the mechanisms and evolution of the westerlies still unresolved. In this fellowship, we will address this issue by studying the Holocene sediments recovered from the deep Dead Sea. The deep Dead Sea temperature is mainly influenced by winter air temperature and its level depends on the Jordan discharge that is fueled by winter rainfall, making this site ideal to reconstruct the winter variables affected by the westerlies. We will use novel methods based on spectroscopy and spectrometry on salt fluid inclusions (FIs) to reconstruct Holocene lake temperature and composition and we will develop a new method exploiting the lake composition, thickness of deposited salt, speed of sound in FIs, sediments microfacies and X-ray fluorescence elemental composition to reconstruct lake levels. As, in these arid latitudes, it has been impossible so far to obtain Holocene winter temperatures and hydrological reconstructions are scant, and because this site responds in an unusual way to changes in westerlies, I believe this action will prove key in understanding the evolution of the westerlies.

Keywords: salt fluid inclusions,dead sea,westerly winds,winter air temperature,lake level,holocene
Multimedia and Augmented Radio Creation: Online, iNteractive, Individual (MARCONI)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Austria,Austria,Germany,Switzerland,Belgium,Belgium,Belgium,Netherlands,United Kingdom
Call: Media and content convergence (H2020-ICT-2016-2, 2016)
Start date: 2017-09-01
End date: 2020-03-31
Duration (months): 31.0
Total project cost (EUR): 3667629.24
EU funding (EUR): 3231374.5
Participants: 10
Project status: CLOSED

Nowadays, radio shows surpass linear broadcast feeds by increasingly revolving around user engagement, which encompasses audience interaction and experience personalisation. Indeed, a typical consumer increasingly interacts with the radio station through digital platforms and social media. Unfortunately, the tools to enable radio-makers to capitalize on these new kinds of media and interaction opportunities are premature at best, and are in addition ill-aligned with contemporary radio production workflows. MARCONI aims to bring radio experiences to the next level, enabling radio to safeguard its strong position in the European media market, while at the same time facilitating innovative ways of radio making. The goal is to enable fully interactive and personalised radio solutions, integrating broadcast radio with digital and social media, amounting to converged radio experiences. To realize this goal, MARCONI will pursue two concrete objectives. First, consumers will be able to interact with “live” radio through their preferred communication channel in ways that are richer than is feasible today, so that consumers feel more connected to the radio brand -even when not listening linearly- and better served in an individual way. Second, radio-makers will be given an integrated view on audience interactions and will be supported by interaction automation services. The net outcome will be enhanced audience engagement. MARCONI brings together a multi-disciplinary consortium to realize its vision. Several partners will focus on AI to automate processing of audio-visuals, text and social media posts. A radio redaction solutions provider is represented in the consortium to guarantee smooth integration in real operational workflows. MARCONI also includes broadcasters which will organise large-scale pilots with their respective communities. Finally, strong industry participation (SMEs and radio stations) ensures that the MARCONI market potential will be properly exploited.

Keywords: interactive radio,radio convergence
Chemical Engineering of Functional Stable Metal-Organic Frameworks: Porous Crystals and Thin Film Devices (chem-fs-MOF)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Spain
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-01-01
End date: 2022-12-31
Duration (months): 72.0
Total project cost (EUR): 1527351.26
EU funding (EUR): 1527351.26
Participants: 1
Project status: CLOSED

Metal-Organic-Frameworks (MOFs) offer appealing advantages over classical solids from combination of high surface areas with the crystallinity of inorganic materials and the synthetic versatility (unlimited combination of metals and linkers for fine tuning of properties) and processability of organic materials. Provided chemical stability, I expect combination of porosity with manipulable electrical and optical properties to open a new world of possibilities, with MOFs playing an emerging role in fields of key environmental value like photovoltaics, photocatalysis or electrocatalysis. The conventional insulating character of MOFs and their poor chemical stability (only a minimum fraction are hydrolytically stable) are arguably the two key limitations hindering further development in this context. With chem-fs-MOF I expect to deliver: 1. New synthetic routes specifically designed for producing new, hydrolytically stable Fe(III) and Ti(IV)-MOFs (new synthetic platforms for new materials). 2. More advanced crystalline materials to feature tunable function by chemical manipulation of MOF’s optical/electrical properties and pore activity (function-led chemical engineering). 3. High-quality ultrathin films, reliant on the transfer of single-layers, alongside establishing the techniques required for evaluating their electric properties (key to device integration). Recent works on graphene and layered dichalcogenides anticipate the benefits of nanostructuration for more efficient optoelectronic devices. Notwithstanding great potential, this possibility remains still unexplored for MOFs. Overall, I seek to exploit MOFs’ unparalleled chemical/structural flexibility to produce advanced crystalline materials that combine hydrolytical stability and tunable performance to be used in environmentally relevant applications like visible light photocatalysis. This is an emerging research front that holds great potential for influencing future R&D in Chemistry and Materials Science.

Keywords: materials synthesis,functional advanced materials,metal organic frameworks,porous crystals,chemical stability,photocatalysis,structure properties relations
New lightweighting smart surface manufacturing technology for automotive industry (TactoTek)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Finland
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-07-01
End date: 2018-03-31
Duration (months): 21.0
Total project cost (EUR): 3647062.5
EU funding (EUR): 2499663.0
Participants: 1
Project status: CLOSED

TactoTek is a Finnish SME, founded in 2011, that manufactures structural electronics by integrating printed circuitry and discrete electronic components into 3D injection-moulded plastics. With TactoTek key aspects of a device’s intelligence and functionality can disappear into the plastics themselves and become durable structural electronics. TactoTek’s thin 3D formed components bring superb weight and design benefits for the European automotive industry. In the competitive Automotive market, TactoTek can answer the European OEM’s need for luxurious interior styling at a lower price point while reducing vehicle weight. TactoTek parts can replace inert structural components, reduce assembly steps, and minimize complicated electrical connections to deliver a competitive total cost solution. In addition, TactoTek structural electronics are manufactured using standard mass production equipment for production efficiency and scalability. TactoTek has demonstrated and validated its technology in multiple prototype and NRE projects in collaboration with global customers. The purpose of this 18 month project is, for the first time in the world, to demonstrate mass production manufacturing volumes and quality by conducting pilot mass production of structural electronics. Doing so will enable TactoTek to enter the global Automotive market in which TactoTek technology has significant customer pull. Recognized by analysts, customers and partners, TactoTek is the technology leader in structural electronics for automotives. In addition to piloting mass production, this project will prepare TactoTek to scale production through licensing its manufacturing methods and partnering with OEMs, Tier 1 –3 vendors and their manufacturing service providers to satisfy growing global demand.

Keywords: structural electronics,in mold electronics
Network for European Research and Innovation acceleration in the US (NearUS)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Innovative societies
Action type: Coordination and support actions
Countries involved: Germany,Belgium,Hungary,France,France,United States,Luxembourg,Portugal
Call: Centres/Networks of European research and innovation (H2020-SC6-ENG-GLOBALLY-2016-1, 2016)
Start date: 2017-04-01
End date: 2020-09-30
Duration (months): 42.0
Total project cost (EUR): 2999917.5
EU funding (EUR): 2999917.5
Participants: 10
Project status: CLOSED

NearUS aims at establishing a Butterfly Network of Centres of European Research and Innovation as central contact point for support to EU research and innovation (R&I) actors seeking collaboration with and in the US. The NearUS Network/Centre will be coordinated through two nots in the EU and the US and be physically established in two main locations of interest (“landing hubs”) in the heart of the US eco-system: Silicon Valley and Boston. Additional network members will be added through “Associated Centres”, and the network establishment will build on strong existing ties, ensuring access to EU potential beneficiaries from all EU Member States and US actors from all over the US so as to set up a consolidated structure of support: the currently dispersed services from a multitude of EU and EU Member States initiatives will be brought under one umbrella. In order to ensure a sustainable set up and implementation of the Butterfly Network of Centres of European Research and Innovation, the project team will proceed with a clear methodology: Firstly, an analysis of the existing offer combined with a needs analysis from potential customers will be undertaken, as well as the set-up of an operational roadmap based on a subsequent gap analysis. The establishment of the two pilot “soft landing” hubs with adapted business models and concrete business plans will follow, as well as long-term financial planning. A variety of services will be developed and proposed to customers during a pilot phase, then the centres and their pilot activity will be evaluated and the activity where necessary optimized so as to ensure the sustainable implementation. Services will target R2R, R2M and B2B cooperation, such as matchmaking opportunities, working visits to US institutions, pitching in front of Venture Capitalists, etc. Close coordination and targeted dissemination to relevant stakeholder groups will of course accompany the development of the Network of Centres.

Keywords: eu us collaboration,sustainable network of centres,research to research,research to market and business to business services,training and events
Imagination As A Lens (IAL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 160800.0
EU funding (EUR): 160800.0
Participants: 1
Project status: CLOSED

Invocations of the imagination to describe and explain aspects of our thought and action are commonplace all across philosophy: in metaphysics, epistemology, ethics, aesthetics, philosophy of mind, of science, and so on. Beyond philosophy, imagination is also invoked in psychology, religious studies, English literature, anthropology, and other disciplines. The diversity of these invocations raises the worry that there is no unanimous conception of imagination lying behind them; if this is so, the explanatory concept being invoked is ambiguous and perhaps vacuous. The aim of this project is to argue for a unified conception of imagination, the lens approach, via three research objectives: (1) to motivate a unified conception by arguing that it’s possible and desirable; (2) to articulate and argue for the lens approach as the best such conception; (3) to apply the approach to two problems of imagination, thus demonstrating its utility. Each objective will result in two papers. The project also incorporates a fourth outreach objective involving training and participation in public engagement. The project matches the theoretical expertise, in-depth topic knowledge, and international training of the Experienced Researcher (ER) with the empirical experience, wide subject background, and advantageous collaboration networks of the supervisor, Bence Nanay, and the host organisation, the University of Antwerp’s Centre for Philosophical Psychology. The project will substantially improve the ER’s career prospects, especially given the supervisor’s excellent track record of training post-doctoral researchers; meanwhile, the host will benefit from the ER’s contribution to its research activities, and acquire greater networking and collaboration opportunities both during and after the project.

Keywords: imagination,philosophy of mind,transformation,imitation,simulation,visualization,empathy