Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
When Satellite Navigation Meets Satellite Communication in Low-Earth-Orbit Satellite Systems (INAC-LEO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-12-01
End date: 2026-11-30
Duration (months): 24.0
Total project cost (EUR): 191760.0
EU funding (EUR): 191760.0
Participants: 1
Project status: CLOSED

In the realm of satellite systems, communication and navigation have traditionally functioned as separate systems, each requiring its own dedicated hardware. However, emerging wireless technologies present a game-changing opportunity: they can enhance navigation capabilities by the Low-Earth-Orbit (LEO) satellite systems and enable integrated systems that serve both communication and navigation requirements. This project aims to unlock the untapped potential of LEO satellite systems for Integrated Navigation and Communication (INAC), a critical step for Europe in developing cost-effective, dual-purpose satellite systems that could transform emergency services and Internet of Things (IoT) applications. The project is structured around three key objectives. Firstly, with the aid of LEO communication satellites planned by the European Union, Work Plan 1 (WP1) will establish a theoretical framework for LEO satellite navigation by using dynamic constellation characteristics and Doppler information. Secondly, WP2 will design a communication-aided navigation system that leverages the low-latency and high spectral efficiency of LEO communication satellites, aiming to enhance accuracy while minimizing computational demands. Lastly, WP3 will develop an integrated system that combines communication and navigation using next-generation multiple-access (NGMA) techniques, ensuring optimal performance in both communication and navigation without compromise. With a projected market impact potentially surpassing 10 billion Euros, this initiative stands to make a substantial contribution to the European space ecosystem, while providing groundbreaking solutions to global communication and navigation challenges.

Keywords: satellite navigation and communications,next generation multiple access,6g wireless networks
REVEALing complex strain patterns and dangerous loads using cholesteric liquid crystal elastomers (REVEAL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Luxembourg
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-09-01
End date: 2024-02-29
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The Internet of Things (IoT), Industry 4.0, and the increased availability and performance of sensors have led to new generations of ‘smart’ products that can communicate real-time status information, improving energy balance, increasing safety, and opening for better, more seamless experiences for consumers. Mechanical sensors—often measuring strain—are key components in many scenarios. However, current technology typically employs point-based or one-dimensional (1D) strain sensors of resistive, piezoelectric or optical fiber type, with low spatial resolution (one sensor, one value), giving limited information about complex deformations and even missing dangerous strains slightly away from the sensor. There is thus a need for new solutions that offer 2D distributed strain sensing with high resolution. We recently proposed two new concepts for non-electronic strain sensing, both based on the mechanochromic response of Cholesteric Liquid Crystal Elastomers (CLCEs), changing colour in response to mechanical deformation. The value proposition of REVEAL comprises simple and scalable procedures for making CLCE sheets of large size and fibers of arbitrary length, which exhibit excellent local mechanochromic response (from red to violet) upon strains of up to 200%. Within REVEAL, we will produce CLCE sheets and fibers and assess their application potential, for instance, in structural health monitoring of the built environment, smart clothing and sports gear. The challenges we wish to take on in REVEAL are: ensuring consistent and tuneable relaxed colour with sufficient time stability of our CLCE sheets and fibers; allowing adjustable and well-defined diameter of the CLCE fibers; reducing tackiness of the fibers, thus enabling easy manipulation and processability at large scale; ensuring strong full-area bonding to each relevant target surface of the CLCE sheets; and assessing the usefulness in four specific target applications, two for each CLCE type.
MultidiSciplinary and MultIscale approach for coupLed processes induced by geo-Energies (SMILE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,Netherlands,Italy,United Kingdom,France,Norway,Czechia,Switzerland
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 2626049.83
EU funding (EUR): 2413274.4
Participants: 16
Project status: SIGNED

Geo-energies, such as geothermal energy, CO2 storage and underground energy storage, have a great potential to contribute to meet the Paris Agreement targets on climate change. Yet, their deployment has been hindered by a lack of a full understanding of the processes that are induced in the subsurface by large-scale fluid injection/extraction. The various processes involved (e.g., fluid flow, geomechanical, geochemical and thermal effects) imply complex interactions that cannot be predicted without considering the dominant coupled processes, which is rarely done. As a result, some early geo-energy projects have occasionally developed unpredicted consequences, such as felt and damaging induced earthquakes, gas leakage and aquifer contamination, dampening public perception on geo-energies. SMILE aims at overcoming these challenges in developing geo-energy solutions by training a new generation of young researchers that will become experts in understanding and predicting coupled processes. Thus, they will be capable of proposing innovative solutions for the successful deployment of subsurface low-carbon energy sources while protecting groundwater and related ecosystems. To achieve this ambitious goal, the early-stage researchers will be exposed to an interdisciplinary training on experimental, mathematical and numerical modelling of coupled processes, upscaling techniques and ground deformation monitoring using field data from highly instrumented pilot tests and industrial sites. The training in SMILE has been designed by both academic and industrial partners to train competitive researchers with both technical-scientific and transferable skills to enhance their employability in academia, industry and public sector. The outputs of the project will be largely disseminated. Outreach to society will be achieved through a conspicuous series of initiatives. SMILE will make a significant contribution to the societal challenges of securing clean and low-carbon energy sources.

Keywords: fluid injection,pressure buildup,cooling,deformation,geochemical reactions,induced seismicity,remote sensing monitoring,geothermal energy,geologic co2 storage,subsurface energy storage
Reconstruction and Computational Modelling for Inherited Metabolic Diseases (Recon4IMD)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Unlocking the full potential of new tools, technologies and digital solutions for a healthy society
Action type: Research and Innovation actions
Countries involved: Ireland,Italy,Germany,Netherlands,Austria,Belgium,Spain,Sweden,Denmark,Norway,Czechia,Switzerland,United Kingdom
Call: Computational models for new patient stratification strategies (HORIZON-HLTH-2022-TOOL-12-two-stage, 2022)
Start date: 2023-06-01
End date: 2027-05-31
Duration (months): 48.0
Total project cost (EUR): 7881904.71
EU funding (EUR): 7871902.71
Participants: 35
Project status: SIGNED

Our overall objectives are to accelerate the diagnosis, and enable personalised management, of inherited metabolic diseases (IMDs). Established academic technology for statistical genomic analysis, deep learning-based prediction of protein structure, and whole-body metabolic network modelling shall be applied to generate personalised computational models, given patient-derived genomic, transcriptomic, proteomic and metabolomic data. To train diagnostic models, a comprehensive clinical team will recruit 1,945 diagnosed patients with a wide variety of IMDs, then validate the clinical utility of personalised computational models on a set of 685 undiagnosed patients. An enhanced human metabolic network reconstruction, especially for lipid metabolism, reaction kinetics and inherited metabolic disease pathways, will increase the predictive capacity of cellular and whole-body metabolic network models. As an exemplar for other IMDs, personalised computational modelling will be used to identify compensatory and aggravating mechanisms that associate with clinical severity in Gaucher disease. The predictive capacity of personalised models will be validated by comparison with additional empirical investigations of protein structure and function as well as metabolomics, tracer-based metabolomics and proteomics of patient-derived in vitro disease models. To maximise the potential for impact, personalised modelling software will be developed to be generally applicable to a broad variety of IMDs, and implemented in a way that is both accessible to clinicians and admissible to regulatory authorities. Sustainability will be promoted by development of a roadmap for a European foundation to aid personalised diagnosis and management of IMDs, informed by broad stakeholder consultation. This is a unique opportunity to realise the potential of personalised computational modelling for a broad set of rare diseases, which is a field where European collaboration is an essential for progress.

Keywords: inherited metabolic disease,genomics,metabolomics,proteomics,enzyme structure,metabolic network,deep learning,diagnosis,registry,reconstruction,regulatory approval,software medical device
Strengthening the Excellence of Additive Manufacturing Capabilities (SEAMAC)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Slovenia,Germany,Israel
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2023-01-01
End date: 2026-06-30
Duration (months): 42.0
Total project cost (EUR): 1494137.5
EU funding (EUR): 1494137.5
Participants: 3
Project status: SIGNED

Additive manufacturing (AM) has the potential to drive novel industry development as well as to transform current industries, but exploiting it to the fullest requires professionals with advanced degrees who have received the highest-level training in both technical and non-technical competences. The University of Ljubljana has expertise in the direct laser deposition (DLD) process, but has several weaknesses in the areas addressed in the SEAMAC project, including material behaviour especially to master the manufacturing of functionally graded materials and to perform postprocessing of AM parts to improve surface roughness. Hence, leading scientific institutions, namely Technion - Israel Institute of Technology and Technische Universiteat Bergakademie Freiberg take part in the consortium. The former brings expertise in material science and the latter the knowledge on plasma electrolytic polishing. Both institutions are very active in the AM field, have a lot of cooperation with industrial partners, and are skilled in research management. The project activities encompass technical and non-technical cooperation and exchange of knowledge through the workshops and organisation of summer schools.

Keywords: additive manufacturing,plasma electrolytic polishing,functionally graded materials,research management capacities
Plant bioacoustics: on the emission and reception of airborne sounds by plants, and their adaptive value. (PLANT BIOACOUSTICS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Environmental B iology, Ecology  and E volution
Panel description: For all organisms : Ecology, biodiversity, environmental change , evolutionary biology, behavioural ecology, microbial ecology , marine biology, ecophysiology, theoretical developments and mod elling
Countries involved: Israel
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The communication of plants with their environment is crucial for their survival. Plants are known to use light, odours, and touch to communicate with other plants, with pollinators, seed dispersers and herbivores. However, one sensory modality – acoustic communication – is almost unexplored in plants, despite its potential adaptive value. This is the focus of the current proposal. Our long-term goal is to understand the roles of acoustic communication in the life of plants: what plants hear, and what they “say”. The proposed research builds on recent results that strongly suggest the use of airborne sound in plants: We have demonstrated that flowers increase their nectar concentration within minutes in response to the sound of a bee’s wingbeat. Furthermore, we have shown that different species of plants emit brief ultrasonic signals with acoustic characteristics that vary under different conditions. Towards general understanding of plant bioacoustics we will investigate: 1.Plant hearing. We will investigate plant responses to pollinator sounds to uncover their temporal dynamics, mechanism, and evolution. 2.Plant sound emission. We will record the sounds emitted by different plants under different conditions, and use advanced AI to interpret these sounds. 3.Functionality of plant sounds. We will test if and when other organisms – both plants and animals - response to plant sounds, and the potential adaptive value of these responses. The proposed project has the potential to revolutionize our understanding of plants and plant communication. Our results are expected to open entirely new avenues of research such as the evolution of sound communication by plants, and the bio-mechanics of sound emission and sound reception in plants. Our results might also have great applicative implications in precision agriculture, including remote plant monitoring and functional sound emission. These may play a role in fighting the global food-security problem and pollination crisis.

Keywords: sound,airborne,signaling,communication,pollination,nectar,plant pollinator interactions,vibration,drought stress,machine learning,phytoacoustics
Emerging technologies for crystal-based gamma-ray light sources (TECHNO-CLS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany,Italy,United Kingdom,France,Greece
Call: EIC Pathfinder Open 2021 (HORIZON-EIC-2021-PATHFINDEROPEN-01, 2021)
Start date: 2022-06-01
End date: 2027-05-31
Duration (months): 60.0
Total project cost (EUR): 2643187.5
EU funding (EUR): 2643187.5
Participants: 10
Project status: SIGNED

TECHNO-CLS project at the breakthrough in technologies needed for designing and practical realisation of novel gamma-ray Light Sources (LS) operating at photon energies from ~100 keV up to GeV range that can be constructed through exposure of oriented crystals (linear, bent and periodically bent) to the beams of ultrarelativistic charged particles. The TECHNO-CLS high-risk/high-gain science-towards-technology breakthrough research programme will address the physics of the processes accompanying the oriented crystal exposure to irradiation by the high-energy electron and positron beams at the atomistic level of detail needed for the realisation of the TECHNO-CLS goals. A broad interdisciplinary, international collaboration has been created previously in the frame of FP7 and H2020 projects, which performed initial experimental tests to demonstrate the crystalline undulator (CU) idea, production and characterisation of periodically bent crystals and the related theory. TECHNO-CLS aims to build the high-risk/high-gain science-towards-technology breakthrough research programme on these successful studies aiming at a practical realisation of the novel gamma-ray LSs such as CUs, crystalline synchrotron radiation emitters, and many others. Additionally, by means of a pre-bunched beam a CU LS has a potential to generate coherent superrradiant radiation with wavelengths orders of magnitudes less than 1 Angstrom, i.e. within the range that cannot be reached in existing LSs based on magnetic undulators. Such LSs will have many applications in the basic sciences including nuclear and solid-state physics and the life sciences. Theoretical, computational, experimental and technological results obtained in the course of this project will pave a way for key technological developments of the LSs and their wide exploitation. The TECHNO-CLS international collaboration possesses all the necessary expertise to conduct successfully the outlined programme.

Keywords: novel gamma ray crystal based light sources,computational modeling and manufacturing of bent and periodically bent crystals,channeling,radiation,electron and positron beam experiments
Electrochemical fluorination under microflow conditions (ElectronsOnRun)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 191760.0
EU funding (EUR): 191760.0
Participants: 1
Project status: CLOSED

Despite the prevalence of fluorination reactions of organic compounds in the pharmaceutical industry, these reactions still encounter several problems such as low selectivity, yield, high demand on safety operational process and low sustainability. Introduction of fluorine into drug molecules increases the drug’s lipophilicity, improves its stability and pharmacokinetic properties. Thus, the fluorination chemistry is of great importance in a pharmaceutical industry. This project is focusing on fluorination and trifluoromethylation of functionalized piperidines, organic compounds with several biological and therapeutic properties. We propose a cutting-edge interdisciplinary approach to make the fluorination reactions more sustainable, safe and to increase the reaction yield, by transferring electrochemical fluorination reaction into a flow microreactor. Advantage of electrochemical reactions is that the side products are minimized as no chemical reagents are necessary. The main advantages of microreactors are excellent heat and mass transfer properties and high surface to volume ratio. The precise control of the temperature profile in the reactor and the residence time enhances process safety and leads to high reaction selectivity. An electrochemical flow microreactor will be developed and optimized for fluorination reactions of piperidines. Collaboration of organic chemist and chemical engineers is upmost importance to succeed in this interdisciplinary project connecting organic chemistry, flow technology and microreactor engineering. Proposed innovation will show a new specific application of electrochemical microreactor. This is an important step in electrification of chemical and pharmaceutical industry which leads to overall higher sustainability of the chemical production. In addition, by overcoming above mentioned problems with fluorination reactions in the batch, we will demonstrate that microreactors have a valuable place in the chemical industry.

Keywords: electrochemistry,flow chemistry,continuous technologies,microreactor,fluorination,cation flow process,piperidine derivatives
Articular Cartilage Treatment with Injectable hydrogel is Valuable and long-term Effective (ACTIVE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 3692412.25
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Hy2Care brings a regenerative Injectable Hydrogel, of joint- and cartilage-mimicking composition, that is used to treat damaged cartilage. The cartilage defects are easily filled with a syringe during a standard one time arthroscopy. The hydrogel fill the defect, prevents ingrowth of scar tissue and allows the body to heal itself by creating true Hyaline cartilage, ensuring an optimal regenerated tissue. The high-quality regeneration provides the basis for a long lasting repair, postponing or even preventing the onset of osteoarthritis. The gel binds covalently to the surrounding cartilage ensuring integration of the new tissue. Revalidation is fast as the cartilage regrowth follows the degradation of the gel. The lasting repair not only prevents additional secondary treatments but also pain, disability and escalating follow-on costs. In submission of the last cut off of the EIC in october 2020 Hy2Care scored a 14.0 and recieved the seal of excellence.

Keywords: osteoarthritis,cell technology platform,minimal invasive,traumatic focal defect,pma 510k,cartilage regeneration,cartilage repair,tissue regeneration,joint preservation,regenerative medicine,sports medicine,injectable,biodegradable,in situ tissue engineering,joints,knee,hydrogel