Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Demystifying interface accommodation coefficients in liquid-vapor phase change devices: role of surface charge, contaminant, and confinement (DIAL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Switzerland
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-07-01
End date: 2031-06-30
Duration (months): 60.0
Total project cost (EUR): 2329985.0
EU funding (EUR): 2329985.0
Participants: 1
Project status: SIGNED

Liquid-vapor phase change is essential in power generation, heating and cooling, thermal desalination, and membrane distillation. With the advancements enabled by micro/nanoengineering of phase change devices, the interfacial transport resistance becomes increasingly important, dictating the ultimate performance limit. However, fundamental understanding of the interfacial process remains elusive, particularly regarding the interface accommodation coefficients (IACs), which quantify the probability of evaporation and condensation events at the molecular level. Characterizing IACs has been a long-standing challenge, primarily due to the lack of experimental designs sensitive enough to molecule-interface interactions and capable of distinguishing various contributing factors. The DIAL project aims to demystify the complexities surrounding IACs arising from three key factors – surface charges, interface contamination, and nanoconfinement. Here, we decouple these largely overlooked or insufficiently studied factors by designing a series of targeted experiments, leveraging IR and confocal Raman microscopy for combined thermometry and chemical analysis. With evaporating droplets in vacuum, we establish the baseline for IACs first on pure and then on charged and contaminated fluids. Meanwhile, to investigate the effect associated with phase change devices, we characterize contaminant migration and the corresponding impact on evaporation from membranes with microscale pores and at the same time, build a multiscale model relating IACs to device performance. Finally, with evaporation from sparsely spaced nanotube arrays, we examine the nanoconfinement effect on IACs, overcoming the optical diffraction limit. By isolating or minimizing specific effects in each configuration, our experiments collectively advance the fundamental understanding of liquid-vapor interfacial transport while offering practical design insights for all interface-sensitive energy and water systems.

Keywords: evaporation coefficient,condensation coefficient,liquid vapor phase change,surface charge,contamination,nanoconfinement
The Bacillus subtilis circadian clock: from molecules to mutualism (MicroClock)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Germany,United Kingdom,Netherlands
Call: ERC SYNERGY GRANTS (ERC-2024-SyG, 2024)
Start date: 2025-04-01
End date: 2031-03-31
Duration (months): 72.0
Total project cost (EUR): 8301946.0
EU funding (EUR): 8301946.0
Participants: 3
Project status: SIGNED

Circadian clocks are biological timekeepers. They structure processes - from molecular pathways to behavioural attributes - over the 24h day. They are pervasive in eukaryotes yet remain almost completely unknown in bacteria. We propose to address this major knowledge gap by capitalising on our recent breakthrough discovery of a circadian clock in Bacillus subtilis. Our unpublished data reveal that robustness of the B. subtilis circadian clock increases when co-cultured with either the plant Arabidopsis, or the yeast Saccharomyces cerevisiae. We propose that the mutualistic interactions between microbes and other organisms in their environment utilise circadian clocks, allowing us to propose the new concept of “temporal mutualism”. Within this project, we will identify and understand the molecular structure and function of the B. subtilis circadian clock (WP1), which will be the first detailed characterisation of a circadian clock in a non-photosynthetic bacterium. We will exploit the interactions that occur between B. subtilis and plant circadian clocks to define this new concept of temporal mutualism (WP2 and 3). Co-culture of B. subtilis with S. cerevisiae will identify regulatory nodes that are common to plant/bacterium and fungus/bacterium temporal mutualism (WP3). We will probe the novel hypothesis that biofilm enables intra-species temporal mutualism via differentiated cell populations within the matrix-bound structure (WP3). We will use circadian formalisms (behaviour), molecular systems analysis and state of the art technological approaches (e.g., combinations of microfluidics, microscopy, reporter gene technology and optogenetics), which is only possible through our interdisciplinary collaboration. This work will drive a paradigm shift, to open a completely new field that will change current thinking by bridging chronobiology with microbiology and ecology.

Keywords: circadian rhythm,circadian clock,chronobiology,bacillus subtilis,arabidopsis,saccharomyces cerevisiae
COnnecting INVestment Ecosystems by Strengthening Transparency and INclusion (CO-INVESTIN)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Greece,France,Romania,Bulgaria,Belgium,Denmark
Call: Expanding Investments Ecosystems (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-09-04
End date: 2025-09-03
Duration (months): 24.0
Total project cost (EUR): 1423542.43
EU funding (EUR): 996479.7
Participants: 6
Project status: SIGNED

CO-INVESTIN focuses on creating cross-border co-investment opportunities for modest and moderate EU ecosystems by leveraging promising startups in the portfolio of local investors to attract foreign investors from more advanced ecosystems in their new rounds. To achieve that, the partners will pilot the approach in 4 emerging ecosystems (EL, BG, RO, PT) where the consortium partners have a strong footprint and progressively integrate at least 10 additional emerging/ moderate ecosystems by the end of the project. The project focuses on the funding gap around the Series A, very acute in these ecosystems both from the lack of capital and investors perspective, as well as in terms of deal size with respect to more advanced ecosystems. As demonstrated by the recent experience with the EIC Fund, identifying a lead investor and co-investors is a challenging task for DeepTech start-ups, in particular the ones from emerging ecosystems. The CO-INVESTIN approach relies on 4 main dimensions, that cover in a complete manner both the analytic and the action oriented dimensions of the approach: 1. Investment gap analysis, 2. Development of Market Orientation Programmes, 3. Stimulating cross-border investments and 4. Upscaling the framework and enhancing its impacts. The main project results include: • At least 5 working groups to foster the creation of structured and coordinated networks • At least 20 peer investor match-making sessions • Establishment of local CPI and activation of the Assistance Service for foreign investors • Market orientation programmes for European investors, with emphasis on women for at least 10 ecosystems • 5 networking review sessions & VC syndication to encourage joint ventures & Cooperation with innovation agencies • 2 International business forums & conferences to attract and connect investors Particular focus will be placed on fostering the increased participation of women in both the entrepreneurial endeavours, as well as investment landscape.

Keywords: co investment,syndication,series a,funding gap,strengthening investors ecosystems,transparency,inclusiveness
Disrupting purine de novo biosynthesis to fight cancer - from molecules to cells to in vivo studies. (PurHumanDrome)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Poland,Italy,Armenia,Australia,United States
Call: MSCA Staff Exchanges 2023 (HORIZON-MSCA-2023-SE-01, 2023)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 202400.0
EU funding (EUR): 202400.0
Participants: 5
Project status: SIGNED

According to the WHO, in 2022, there were an estimated 20 million new cancer cases and 9.7 million deaths. The proposed project fits perfectly into the Europe's Beating Cancer Plan, in particular the point "Diagnosis and treatment and quality of life of cancer patients". This project combines the expertise of scientists and academic centres from five different countries in three continents who are applying their knowledge at the frontiers of biology, chemistry, bioinformatics, biophysics and medicine to find a specific inhibitor for the ATIC enzyme involved in de novo purine biosynthesis. We have developed a number of new peptide-like compounds (and more compounds will be uncovered by bioinformatics tools) and will evaluate their efficacy in inhibiting the dimerisation of the enzyme ATIC monomers. The studies will also be conducted in cancer cell lines and in Drosophila flies. The outcomes can not only improve the health of society, but also provide new insights into metabolic pathways in cancer. The project will involve young and experienced scientists from EU countries, the USA and Australia. Scientists who have previously worked on the interactions of molecules in vitro will learn how to work with animal models and how to conduct in silico studies. Those who have previously used structural spectroscopy techniques in their work will learn physico-chemical methods, e.g. isothermal titration microcalorimetry ( ITC) and microscopic techniques. In addition, European scientists will have the opportunity to improve their ability to communicate and present their work results in English, to enter into new collaborations and to form their own international teams. Up-to-date information about the project will be published on the websites of all consortium partners involved in this project. We also plan to organise at least one live workshop. Every effort will be made to ensure gender balance at all levels of staff involved in the project.
Prototypes for addressing the housing-energy-nexus (PREFIGURE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Social and Economic Transformations
Action type: Research and Innovation actions
Countries involved: Germany,Bulgaria,Sweden,Spain,Netherlands,Italy,United Kingdom,Estonia
Call: Addressing housing inequalities in a sustainable, inclusive and affordable way (HORIZON-CL2-2023-TRANSFORMATIONS-01, 2023)
Start date: 2024-04-01
End date: 2027-03-31
Duration (months): 36.0
Total project cost (EUR): 2777058.76
EU funding (EUR): 2777058.75
Participants: 12
Project status: SIGNED

European societies are confronted with an interlinked housing and energy crisis that is challenging social cohesion. As access to affordable housing becomes limited, inflation and accelerating energy prices pinpoint that energy poverty and housing inequalities mutually reinforce. Within this context, the deep renovation of the existing housing stock is promoted as key policy action. However, despite policy efforts from the EU to the local state, there are growing concerns that the transformation of housing markets may further aggravate the existing housing inequalities and energy poverty. To offer more equitable pathways to the green transition, PREFIGURE puts the spotlight on existing and emerging individual and collective efforts of policy, market, and social innovation. The project aims at identifying, tracing, analysing and networking emerging and active ‘prototypes of change’ with regard to the housing-energy efficiency/energy poverty nexus. Research objectives are to: (i) offer understanding of how practices of innovation contribute to affordable housing renovation schemes that disrupt existing housing inequalities and energy poverty; (ii) identify how housing policies trigger sustainable housing and energy transitions, how financial incentives for energy-efficient buildings are accessed by different types of owners and tenants, and how different user groups perceive sustainable housing and energy transitions, with a particular focus on income and wealth polarisation consequences on vulnerable groups; and (iii) mobilise knowledge about innovative practices for sustainable housing and energy transitions and co-create evidence-based policy solutions. Method innovation relies on fusing transformative qualitative and quantitative with technological and real-laboratory research to co-create and up-scale knowledge and practices that signal the green transition.

Keywords: housing inequalities,energy poverty,social innovation
Towards GEO 2025@Rome (2RomeGEO2025)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Coordination and support actions
Countries involved: Italy
Call: Support to GEO annual event 2025 (HORIZON-CL6-2024-GEO-IBA, 2024)
Start date: 2024-07-16
End date: 2025-07-15
Duration (months): 12.0
Total project cost (EUR): 1000000.0
EU funding (EUR): 1000000.0
Participants: 1
Project status: CLOSED

The GEO post-2025 Strategy endorsed by Ministers at the GEO Ministerial Summit held in Cape Town in November 2023 has clarified the GEO post-2025 goals and objectives. To empower users in making sound environmental decisions, enable economic opportunities and promote good governance, the Strategy intends to follow up on its commitment to promote data and knowledge sharing and the co-development of services; as new purpose for the coming years GEO will have to make a step forward in the EO value chain (the “last mile”) by providing what has been defined “Earth Intelligence for All (users)”. The event will be a great opportunity for promoting an open debate between high-level Countries’ Representatives and other high-level Representatives from UN bodies, science, NGOs, Youth’s organizations on how Earth Intelligence should be laid down at local scale to implement cost-effective strategies to mitigate the effects of major global threats (climate change, biodiversity loss, natural disasters, urban areas). “Earth Intelligence for All (users)” includes the concept of making resources (data, tools, knowledge) and opportunities (financial) available to different communities (scaling down, scaling up) with varying needs and capacity: in one sentence, “Global Equity in benefitting from progress produced by the use of Earth observations data, technologies, tools and knowledge which represent the essence of Earth Intelligence for All)“. Additionally, a specific attention will be devoted to the involvement of youth in GEO Work Plan’s activities. Towards GEO 2025@Rome will be hosted in Rome and organized by Agenzia Spaziale Italiana in a way to maximise the involvement of stakeholders at national and international level and to increase the engagement of users and capacity building.

Keywords: earth observation,event,geo,earth intelligence,youth,copernicus,eo services,users,satellite,eo value chain
Advanced Butanol and Hexanol Production from CO2: Integrating Genetically Modified Clostridium strains in Bioelectrochemical Systems (Bioelectrochemistry)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-08-01
End date: 2028-07-31
Duration (months): 24.0
Total project cost (EUR): 252180.0
EU funding (EUR): 252180.0
Participants: 1
Project status: SIGNED

The production of butanol and hexanol from syngas (CO and CO2) fermentation represents a significant advancement in sustainable chemical manufacturing. This project aims to enhance the efficiency of this process by leveraging the capabilities of Clostridium ljungdahlii, a bacterium known for its robust syngas fermentation capabilities. C. ljungdahlii can convert CO2 into valuable products like butanol and hexanol, but current production levels are limited. Existing research shows that engineered strains of Clostridium can produce butanol at levels of 6–8 g/L from syngas. With ongoing advancements in genetic engineering, these yields are expected to rise to 10 g/L, and potentially up to 20 g/L with further metabolic engineering and optimized fermentation conditions. Similarly, while current hexanol production stands at 1–2 g/L, genetic engineering holds the potential to increase this to 2–3 g/L by enhancing chain elongation and managing acetate accumulation. The project here focuses on two main objectives: a) optimizing genetic modifications in Clostridium strains and integrating bioelectrochemical systems (BES) to address the current limitations. Genetic engineering efforts will target the Wood-Ljungdahl pathway (WLP), a crucial metabolic route for converting CO2 and CO into acetate. By knocking out the acoA gene (acetyl-CoA synthetase) and upregulating adhE (alcohol dehydrogenase), we aim to redirect carbon flux from acetate production to alcohol synthesis. Additionally, utilizing BES will help mitigate acetate toxicity and enhance product yields through electrochemical stimulation, which improves cellular redox metabolism and supports the conversion of excess acetate into butanol (C4) and hexanol (C6). In effect, this combined approach will increase the production of multi-carbon chemicals in the system, which will provide new insights and improved efficiency in BES for increased CO2 fixation and bioconversion.

Keywords: bio electrochemistry,microbes,carbon sequestration,acetate,butanol and hexanol
Fostering European Talents for Widening Circular Economy (Talent Pass)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Coordination and support actions
Countries involved: Romania,Slovenia,Portugal,Spain,Italy,United Kingdom,Türkiye
Call: ERA Talents (HORIZON-WIDERA-2024-TALENTS-03, 2024)
Start date: 2025-06-01
End date: 2029-05-31
Duration (months): 48.0
Total project cost (EUR): 2999810.0
EU funding (EUR): 2999810.0
Participants: 10
Project status: SIGNED

The Talent Pass initiative is designed to: - strengthen the innovation ecosystem towards a borderless research, innovation (R&I) and technology market by addressing the critical need for geographically balanced talent circulation and increased cross-sectorial interoperability, as outlined in Action 4 of the ERA Policy Agenda (2022-2024); - cultivate and support cross-sectorial partnerships between academic and non-academic organizations that operate in areas of proven scientific excellence, particularly within the realm of the circular economy. The Talent Pass project aims to: - significantly enhance talent mobility and expertise development within circular economy, particularly focusing on researchers, innovators, and other R&I academic/non-academic talents from widening countries; - build a critical mass of competent researchers having the necessary high-quality knowledge, skills, and tools to drive forward innovation and sustainability in the circular economy; - improving access to excellence by consolidating an interdisciplinary network of highly skilled human resources and enhance the efficient utilization and valorization of complementary research capacities, infrastructure and results, aligning with the Horizon Europe Work Program (2023-24) - WIDERA and the Circular Economy Action Plan for a Cleaner and More Competitive Europe (2020); - bridge the gap between research and application and effectively translate advancements in circular economy into real-world solutions, by fostering collaboration between academia and industry. Talent Pass will subsequently focus on strengthening the research capabilities of WC institutions, ensuring they are on par with leading European entities. This will be achieved through strategic use of research resources (human, know-how and infrastructure) to foster capacity-building initiatives and targeted training and secondment programs addressing current and future challenges in circular economy.

Keywords: european,talents,widening,circular,economy
Chaos and thermal effects in black hole interactions (BlackHoleChaos)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Greece
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 153486.72
EU funding (EUR): 153486.72
Participants: 1
Project status: CLOSED

The understanding of the microscopic origin of chaos and thermal effects in the physics of black holes is very challenging. Such fundamental aspects seem to be intimately connected, but a microscopic analytical description of their interplay is still missing. The quantum gravity description of these aspects could help clarify their microscopic interconnection. The project I propose has the ambition to probe black hole states through highly excited string and coherent string states, providing a quantum microscopic description of chaos, thermal effects and information theory. The main observables are scattering and decay processes. The research programme contains the following parts. First, a general strategy will be developed to measure, and analytically control, chaos in physical processes involving black holes, such as black hole decays and black hole Compton scattering. In particular, a quantitative measure of chaos will be introduced using Random Matrix Theory techniques and the relative Lyapunov exponents will be computed. Second, in order to study thermal effects in black hole processes, the triggering of the thermalization phase driven by chaos will be investigated. Finally, the project will consider the following direct applications. The first one will be the study of chaotic signatures in wave forms and quasi-normal modes of gravitational and electro-magnetic waves; the second will concern the realization of black hole horizons in terms of highly excited string and coherent string form factors.

Keywords: black holes,thermalization,chaos,string theory,string excited states,string scattering