Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Bilingualism in Florentine and Tuscan Works (ca. 1260 - ca. 1416) (BIFLOW)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Italy,France
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-10-01
End date: 2021-06-30
Duration (months): 69.0
Total project cost (EUR): 1480625.0
EU funding (EUR): 1380625.0
Participants: 2
Project status: CLOSED

This project will undertake the first systematic investigation of the various literary documents that circulated simultaneously in more than one language in Tuscany, and especially Florence, between the mid-13th Century and the beginning of 15th Century. During that period, Florence was both a prominent literary centre in the vernacular, and home to a renewal of classical Latin eloquence. While both fields are well studied, their interaction remains largely unexplored. This research, at the convergence of several disciplines (literature, philology, linguistics and medieval history), has a strong pioneering character. It aims at changing the perception of medieval Italian culture and interpretation of the break between medieval Culture and Humanism. For this reason, the project will develop research in varying degrees of depth. First, it will provide the first catalogue of bilingual texts and manuscripts of medieval Tuscany. Organized as a database, this tool of analysis will stir innovative research in this field, some of which will be immediately promoted during the project. Secondly, two case studies, considered as important and methodologically exemplary, will be researched in detail, through the publication of two important set of texts, of secular and religious nature : 1. The vernacular translation of the Latin Epistles of Dante Alighieri; 2. A collection of polemical, historiographical, devotional and prophetical documents produced by the Tuscan dissident Franciscans in last decades of the 14th Century. Finally, the entire team, led by the PI, will be involved in the preparation of a synthesis volume on Tuscan culture in the fourteenth century viewed through bilingualism, entitled Cartography of bilingual culture in Fourteenth-Century Tuscany. From this general map of the Italian culture of the time, no literary genre nor field (be it religious or lay) shall be excluded.

Keywords: medieval bilingualism and diglossia,medieval culture and humanism,medieval religious history,dante alighieri,volgarizzamenti and medieval translation,latin and vernacular manuscripts
TRANSITION - Tool-Part-Interaction simulation process linked to laminate quality (TRANSITION)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Germany
Call: Tool-Part-Interaction simulation process linked to laminate quality (H2020-CS2-CFP02-2015-01, 2015)
Start date: 2016-07-01
End date: 2019-12-31
Duration (months): 42.0
Total project cost (EUR): 348125.0
EU funding (EUR): 348125.0
Participants: 1
Project status: CLOSED

Highly integrated, complex composite structures require a thorough evaluation of processing tools and parameters in order to achieve a competitive time-to-market as well as a cost efficient solution. The link between processing conditions and final laminate quality as to porosity and geometric deviations can be captured by processing simulation tools. Goal of this project is to adapt and implement two existing model approaches into an ABAQUS framework to be able to validate and adapt the tooling concept early in the design process. One of the models will be implemented as a subroutine in ABAQUS to capture the prepreg consolidation depending on the prevailing processing conditions, while the second model is subsequently capable of predicting the porosity within the part depending on the temperature and pressure history. The predicted part quality will be compared with physical experiments on parts with increasing complexity.

Keywords: laminate quality,simulation,prepreg,tool part interaction
Quantifying the relative importance of natural and anthropogenic drivers of spatial variation in vulnerability to predict species extinction risk (DRIVE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-10-01
End date: 2019-01-20
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

The world is losing biodiversity at an unprecedented rate, altering the functioning of Earth’s ecosystems and their ability to provide society with the services needed to prosper. To prevent biodiversity loss it is critical to understanding species extinction patterns. Studies linking species extinction risk with biological traits provide good insights but models show small predictive power generating uncertainty about how to translate knowledge into conservation strategies. Since global species extinction is the result of a sequence of local population extirpations, it becomes more meaningful understanding vulnerability at population level. This implies knowing the drivers of population extirpations within the species geographical context. This spatial context is determined by ecological and evolutionary factors that imprint to local populations a natural ability to tolerate anthropogenic threats. Focusing on terrestrial mammals, DRIVE aims to quantify the relative importance of natural and anthropogenic factors in driving local populations to collapse. For this, DRIVE proposes to build a novel hierarchical biogeographic template to incorporate the species environmental context into ecological models. The ultimate goal is to include the species inherent vulnerability as a key intrinsic trait into models predicting species extinction risk. DRIVE objectives will be accomplished by using innovative methods and novel theoretical advances in ecology, working in a multidisciplinary context involving biogeography, population modelling, and applied conservation. DRIVE is a collaborative project between EBD-CSIC (Spain, beneficiary) and the Department of Zoology-Oxford University (UK, partner), which outcomes will contribute to the consolidation of the European Area on biodiversity conservation, and are in line with current European societal demands and the Aichi Biodiversity Targets for 2020 by the United Nations Convention on Biological Diversity.

Keywords: biodiversity loss,bioregions,environmental variability,extinction drivers,forest fragmentation,human impacts,mammals,range loss,traits
Structural and functional characterization of large viral and human non-coding RNA motifs involved in HIV infection (3DviralRNA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

HIV infections cause 1.2Mi deaths/year worldwide at steadily-increasing rates, partly because of antiretroviral resistance and the impossibility of eradicating latent viruses. To expand our understanding of HIV pathogenesis, we need to unravel all molecular mechanisms involved in HIV progression. Large viral and human RNAs are emerging as key players in HIV infection. To characterize such RNAs, I will employ an integrated structural biology approach complemented by biochemical and functional assays in vitro and in vivo and I will address two fundamental questions: 1. How does the structure of HIV genomic RNA regulate HIV infectivity? HIV genomic RNA regulates nuclear export, packaging, splicing, and translation of viral proteins. 3D structures are known for short motifs (<200 nt), e.g. TAR and RRE. Such motifs are part of 11 larger domains (>400 nt), whose structures are unknown but conserved across HIV strains suggesting functional importance. We will study domain 2 (450 nt), which encompasses the gag-pol frameshifting motif and is crucial for correct protein synthesis. Our work will offer unprecedented insights into the structural complexity of the genome of an RNA virus. 2. How does the structure of human long non-coding RNAs (lncRNAs) affect the host-cell response to HIV infection? HIV infections alter expression of human lncRNAs, e.g. HOTAIR, which regulate Polycomb chromatin remodeling enzymes, e.g. PRC1/PRC2, favoring epigenetic silencing and latency of HIV genes. Interactions between HOTAIR and PRC1/PRC2 are not well characterized at the molecular level. We will study HOTAIR domain 1 (530 nt), which interacts with PRC1/PRC2 and regulates their cellular action. Such work will reveal novel mechanisms of epigenetic gene-silencing that induce HIV latency. By revealing molecular details of HIV and human RNAs, our study will enrich our understanding of HIV infectivity, potentially opening new ways for future therapies against RNA viruses.

Keywords: integrated structural biology,rna crystallography,viral host cell interactions,long non coding rnas,human immunodeficiency virus
INfrared STRUctural monitoring of Cracks using Thermoelastic analysis In production enVironmEnts (INSTRUCTIVE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: United Kingdom,United Kingdom
Call: Development of Thermoelastic Stress Analysis for the detection of stress hotspots during structural testing (H2020-CS2-CFP01-2014-01, 2014)
Start date: 2016-01-01
End date: 2018-12-31
Duration (months): 36.0
Total project cost (EUR): 386062.5
EU funding (EUR): 349558.88
Participants: 2
Project status: CLOSED

This proposal is built around a well-established set of laboratory-based techniques, which use Thermoelastic Stress Analysis (TSA) for characterising strain fields associated with structural features. It is proposed to extend their applicability to aircraft structure tests and to enhance their productivity through the use of automation for data acquisition and processing in an industrial environment. Thermoelastic stress analysis is well-established as a laboratory-based technique and its use for structural analysis , fracture mechanics and damage mechanics has been explored extensively. Most of the work so far has been performed using relatively small test coupons with simple structural features. In the proposed work the aim is to prove the feasibility of applying thermoelastic stress analysis in a structural test environment for detecting stress hotspots. The structural test tools developed will enable fast acquisition of data-rich stress fields in large aerospace components during structural tests at relatively low cost and the post-processing capabilities will allow meaningful comparison of experimental results with those from computational models and service life evaluations. The scientific and technical objectives are designed to lead to innovative methodologies that will enable more detailed stress information to be acquired during aircraft structure tests. These methodologies will be faster, lower cost and provide higher confidence in computational models than is possible at the moment.

Keywords: thermoelastic stress analysis,infrared stress measurement
Machine Learning for String Field Theory and for the String- and F-Theory landscapes (ML4SFT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France,United States
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-11-01
End date: 2023-10-31
Duration (months): 36.0
Total project cost (EUR): 275619.84
EU funding (EUR): 275619.84
Participants: 2
Project status: SIGNED

String theory is one of the leading endeavours in theoretical physics to construct a theory of quantum gravity unified with all interactions and matter. As such, it provides a complete description of the Universe and of its content. However, while all ingredients are present, the details for a precise contact with the Standard Model and with our Universe are missing, mostly because the number of possible realizations is huge and no selection mechanism is known. Moreover, progress is further hindered, for the description of string theory as a field theory - arguably its most fundamental formulation - is very intricate. Since the most immediate difficulties are computational - it boils down to studying statistics of geometries (the "string landscape") and to approximating functions and geometries (to build a string field theory) - machine learning seems to provide an adequate framework to address the challenges faced by string theory. The first aspect of this project is to elaborate machine learning tools for constructing the string field theory action while deepening in parallel our analytic understanding of closed string field theory. For the latter, the main objective is to include auxiliary fields and to investigate whether the action can be made cubic. The second aspect is to design machine learning algorithms to map the string landscape. This project holds the promise of important developments in our understanding of string theory and in its applications to phenomenology. It is located at the intersection of multiple disciplines - theoretical physics, mathematics (Riemann surfaces and homotopy algebras) and machine learning. The choice of institutions and supervisors reflect this interdisciplinary aspect: Prof. Zwiebach is an expert in string (field) theory and in the moduli space geometry, while Dr. Tamaazousti is a specialist of machine learning. Furthermore, both institutions are renowned in these domains.

Keywords: string field theory,string amplitudes,string landscape,homotopy algebra,riemann surface,machine learning
Innovative Mechanically Pumped loop for ACtive Antennae (IMPACTA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling advances in space technology
Action type: Research and Innovation actions
Countries involved: Spain,Belgium,Switzerland,France,France,Netherlands,Netherlands
Call: Generic space technologies (H2020-SPACE-2018, 2018)
Start date: 2019-01-01
End date: 2022-09-30
Duration (months): 45.0
Total project cost (EUR): 3727383.75
EU funding (EUR): 3629455.0
Participants: 7
Project status: CLOSED

The satellite telecommunications industry is currently undergoing significant evolutions. Future commination satellites need to accommodate a rapidly growing demand in data transfer, combined with more flexibility. For example, there is a strong need for Very High Throughput Satellites capable of delivering up to Tb/s over wide coverage areas. This is only possible when an active phased array antenna is used. However, cooling of active antennas requires the use of a highly efficient thermal control system because it has many heat sources (from hundreds to several thousands), very high local heat fluxes (up to 200W/cm² at amplifier interface), high overall dissipation (around 13 kW), and an isothermal requirements on the amplifier chain. These conditions are impossible to solve with current state-of-the-art thermal control solutions (e.g. heat pipes or loop heat pipes), but requires a two-phase mechanically pumped fluid loop (MPL). In a MPL, a pump circulates a fluid which evaporates when it absorbs the waste heat from the active antenna. Although a two-phase MPL is a very efficient thermal control system, it is relative complex and is therefore not yet often used in spacecraft. This proposal aims to change that. The objective of this proposal is to perform research on a two-phase MPL for an active antenna, and to build a demonstrator with a Technical Readiness Level (TRL) of 6. This two-phase MPL will be a key building block in the next generation telecommunications satellites The consortium contains the complete spectrum of partners that are required to successfully research this disruptive novel technology. The consortium contains research institutes (CEA, NLR, CERN), SME’s (AVS, Diabatix) that can eventually commercially supply this technology, and an end-user of the technology (ADS). The consortium takes advantage of its experience in state-of-the-art cooling systems for terrestrial and space applications.

Keywords: active antennae,communication satellites,thermal control
Improving DNA Analysis for Correct Healthcare (IMPACT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Denmark
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 2669623.75
EU funding (EUR): 1868736.63
Participants: 1
Project status: CLOSED

Over the past 10 years DNA sequencing has revolutionized how we apply genetics in personalized healthcare, diagnosis and drug development despite that the sequencing technology comes with numerous shortcomings. Samplix has developed a proprietary technology, Xdrop™, which addresses these shortcomings. Samplix’ technology encompasses state of the art microfluidics, molecular biology and bioinformatics. The Xdrop technology enables scientists and medical personnel to retrieve specific single DNA molecules from a minute amount of biological sample e.g. tumour biopsies, for subsequent DNA sequencing. At the core of the Xdrop technology is the generation of millions of droplets, each droplet constituting a reaction chamber for the sample preparation of single DNA molecules. This is opposed to today’s technology which is based on bulk preparation of sample material for DNA sequencing. Single molecule resolution is key to understanding the complexity of major diseases such as cancer, immunological diseases, mental disorders, etc. The proposed project addresses the need to qualify known market barriers and put measures in place to overcome such market barriers. Samplix has engaged a very experienced management team with an aggregated experience of >50 years in developing and selling products for DNA analysis. Samplix has already established: • 5 test site agreements with leading DNA institutions around the globe • Agreements with leading OEM providers on instrument and consumables • A patent estate of 5 patent families. • Freedom to operate in multibillion € market. At Samplix, we strive at 100 mUSD in revenue and profitability in year five after full commercial launch. To achieve such an ambitious goal, we plan to apply a razor/razor blade sales strategy by installing the instrument “for free” in return for a subscription to consumables Samplix raised 4,5 m€ in May 2018 which brings the total capital raised to 8 m€. A bigger financing round is planned for 2019.

Keywords: personalized medicine,dna variant analysis,next generation sequencing,microfluidic technology
Brain-inspired technologies for intelligent navigation and mobility (iNavigate)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Germany,Germany,Spain,Norway,Belgium,Finland,Romania,Türkiye,Greece,France,Netherlands,United States,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2019, 2019)
Start date: 2019-12-01
End date: 2025-05-31
Duration (months): 66.0
Total project cost (EUR): 1932000.0
EU funding (EUR): 1932000.0
Participants: 32
Project status: SIGNED

iNavigate, a Marie-Curie Research and Innovation Staff Exchange (RISE) consortium, brings together scientists and engineers in academic, private and NGO enterprises. Its goal is to promote international and intersectoral cooperation for the next generation, brain-inspired technologies to facilitate the development of intelligent navigation and autonomous mobility solutions. The consortium exploits the complementary competencies of its members while creating synergy through research, innovation, staff exchange and transfer of knowledge. It actively promotes networking, knowledge utilization and dissemination through summer schools, workshops, conferences, and facilitates new skill acquisition and career development in research, innovation and commercialization.
Heteroepitaxial α-Fe2O3 photoanodes for solar water splitting (EpiAnodes)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Israel
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-01
End date: 2017-09-30
Duration (months): 24.0
Total project cost (EUR): 170509.2
EU funding (EUR): 170509.2
Participants: 1
Project status: CLOSED

Within the past 40 years, tremendous progress has been made in both the efficiency and cost reduction of photovoltaic (PV) cells that convert sunlight to electricity. However, one of the main limitations of using solar power as an energy source is that the electricity must be used immediately or stored in a secondary device . Photoelectrochemical (PEC) cells combined in tandem with PV cells offer a solution to this problem by using solar radiation (light) to electrolyze water and generate hydrogen which can then be converted to electricity using fuel cells or be used to synthesize and store hydrocarbon fuels by hydrogenation of CO2 . The host’s (Prof. Avner Rothschild) research group at the Technion Institute of Technology in Israel has recently made a landmark advancement in the quest for efficient solar water splitting. The development of a resonant light trapping technique in ultrathin absorbing films on reflective substrates opens the possibility to overcome the greatest challenge facing efficient water splitting in α-Fe2O3 photoanodes, namely, the trade-off between optical absorption length and charge carrier collection length. The Experienced Researcher proposes a novel research plan building upon the invention and involving heteroepitaxial deposition of ultrathin Fe2O3 films for solar water splitting. The proposed research is highly innovative and will develop methods for precise control of thin microstructures and their compositions; these will allow for engineering of films that are nearly free of defects which will improve the efficiency of the photoanodes by suppressing bulk recombination and at the same time, cover novel fundamental research directions such as study of doping on α-Fe2O3 properties without entanglement from microstructural effects, heteroepitaxial multilayer structures with selective charge transport layers, and directional charge transport in α-Fe2O3.

Keywords: heteroepitaxial,thin film,photoanode,water splitting,hematite,fe2o3,photoelectrochemical cell,coating,doping,ultrathin film,light trapping,energy conversion,metal oxide,energy storage