Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
BioFunctional IntraNeural Electrodes (BioFINE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Sweden,Germany,Italy,Spain
Call: EIC Pathfinder Open 2022 (HORIZON-EIC-2022-PATHFINDEROPEN-01, 2022)
Start date: 2023-04-01
End date: 2026-09-30
Duration (months): 42.0
Total project cost (EUR): 1945622.0
EU funding (EUR): 1945622.0
Participants: 4
Project status: SIGNED

BioFunctional IntraNeural Electrodes : In BioFINE we will develop flexible intraneural multielectrode arrays, capable of interfacing peripheral nerves e.g. to transfer input/output signals from bionic limbs. Specifically, we address the challenge of long term tissue integration and chronic stability, by addressing three aspects of biocompatibility: 1) We develop novel fabrication methods allowing the intraneural interface to be defined at even finer resolution than before; 2) we explore functionalizations which will control the tissue response by combined surface anchored and surface eluted agents; 3) we address structural biocompatibility on a system level by engineering novel implantable interconnects which reduced tethering forces and improve prospects for high channel count interfaces. Fine-tuned bioactivity will safe-guard surrounding neural tissue in the initial stages of healing, and implants of sub-cellular dimensions and tissue compatible biomechanics, will safe-guard tissue healthy in the longer term. The combined approach will offer optimal conditions to bridge the gap from electrode to neuron and generate a long term functional peripheral nerve interface. Indeed, each of the three technological advancements would on their own have substantial impact on neurotechnology, reaching far beyond intraneural interfaces.

Keywords: peripheral nerve interface,flexible microtechnology,bioelectronics,bionics,biofuntionality
Smart and flexible Separation and Valorisation of mixed bio-waste from along the agri-food value chain. (MixMatters)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Public-private partnerships
Destination: Circular Bio-based Europe
Action type: Innovation actions
Partnership: CBE (JU-JTI)
Countries involved: Spain,Germany,Belgium,Finland,Austria,Italy,Slovenia,United Kingdom
Call: Co-processing of mixed bio-based waste streams (HORIZON-JU-CBE-2022, 2022)
Start date: 2023-06-01
End date: 2027-05-31
Duration (months): 48.0
Total project cost (EUR): 6598412.5
EU funding (EUR): 5651163.5
Participants: 18
Project status: SIGNED

Mixed bio-waste generated along the agri-food value chain is an abundant resource, rich in valuable compounds e.g., polysaccharides or polyphenolic constituents. Yet, its potential as a source of recycled components is untapped - 75% of the generated bio-waste (approx. 85 M/y) is landfilled or incinerated, constituting 3% of total EU GHG emissions. Valorisation of mixed bio-waste from the agri-food sector is hindered by (1) technological challenges of removing impurities (e.g., plastics, cardboard, or metals) that would otherwise decrease the process quality, (2) logistics challenges of collecting seasonal, geographically dispersed feedstock that lower valorisation cost-benefit. MixMatters proposes an innovative system that efficiently separates and valorises three types of mixed bio-waste streams containing impurities from the agri-food industry (wholesale markets, greenhouses, food and drink industry) and obtains six high value-added outputs (powder ingredients, sugar concentrates, recombinant proteins, green fibres, bioactive compounds, plastic monomers). The MixMatters system is modular and multi-purpose - able to treat a range of mixed bio-waste streams (ensuring feedstock supply). The separation stage is automated, integrating advanced robotics and AI. It is also containerised – separating the bio-waste at waste generation sites to avoid inefficient transportation of water and stream spoilage. The system functioning is optimised via a Decision Support while transparency + traceability are ensured via a Digital Product Passport. In the project, the system will be demonstrated during 15 months at three waste generation sites, along with output validation with 6 bio-based industries and active involvement of value chain actors (partner networks outreach + 2,280 members) – to ensure result deployment. MixMatters will contribute to meeting the separation targets of the Waste Framework Directive (separated 6,240 t/y by one system at industrial scale).

Keywords: mixed agri food waste wholesale markets waste greenhouses waste food and drink industry waste high value added outputs upcycled outputs recycled outputs industrial symbiosis
Quantum Engineering of Superconducting Array Detectors In Low-Light Applications (QuESADILLA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2028-08-31
Duration (months): 72.0
Total project cost (EUR): 1844350.0
EU funding (EUR): 1844350.0
Participants: 1
Project status: SIGNED

Optical measurements are fundamental to experimental science and observations of nature. At the single photon level, superconducting nanowire single-photon detectors (SNSPDs) are well-established as the gold standard in measurement, due to their near-unit efficiency, negligible noise and ultrafast response. Building SNSPD arrays and simultaneously extracting intensity, spectral and spatial resolution from a device at the single photon level will revolutionise astronomical measurements, spectrometry in chemistry and life sciences, and quantum imaging. Key to unlocking this potential is to marry concepts from detector tomography with robust high-yield detector fabrication, the integration of complementary optical technologies and low heat-load scalable readout schemes. QuESADILLA tackles these challenges head-on, with a series of experiments demonstrating the groundbreaking potential of quantum detector engineering. In contrast to engineering quantum states of light for metrology, QuESADILLA will shift that paradigm by engineering the quantum mechanical response of the detector itself. QuESADILLA introduces the concepts of a modal decomposition of the positive operator valued measure (POVM), and quantum-enhanced POVM engineering in low-light applications. To do so, arrays of SNSPDs in combination with lithographically-written etalons and dielectric coatings will be developed, in concert with state-of-the-art scalable approaches to large scale quantum tomography. QuESADILLA will exceed the state of the art in many areas: performing the first modal decomposition of detector tomography and the largest tomographic reconstruction of a quantum detector; the first demonstration of quantum detector engineering using nonclassical ancilla states; the first demonstration of etalon array reconstructive spectrometry with single photons; and exploit the fastest electronic shutter speed of any optical sensor to enable the highest dynamic range detection of continuous illumination.

Keywords: superconducting detectors
Mohorovičić discontinuity and Lithosphere-Asthenosphere Boundary (MohoLAB)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: France
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2024-12-01
End date: 2029-11-30
Duration (months): 60.0
Total project cost (EUR): 3498250.0
EU funding (EUR): 3498250.0
Participants: 2
Project status: SIGNED

The Moho and lithosphere-asthenosphere boundary (LAB) are two of the most important boundaries in the Earth. The Moho is the greatest manifestation of the chemically differentiated Earth, separating light rocks in the crust from dense rocks in the mantle whereas the LAB is fundamental for plate tectonics, defining the boundary between the floating rigid lithosphere and the weak, deformable asthenosphere. They are both first born at mid-ocean ridges, where two-thirds of the Earth’s crust and lithosphere are formed, and then evolve with the age, but what happens during the early part of their lives remains an enigma. Together, they serve as the location where coupling and exchange take place between the shallow and deep mantle, and therefore, it is fundamental to understand their formation and evolution during the early stages of their existence. Here, I propose to acquire exceptional seismic data using the most advanced technology available in industry, >2500 Ocean Bottom Nodes, and subject them to the advanced analysis techniques of full waveform inversion, to quantify the nature of the Moho and the LAB during the first 5 Ma of their lives at the fast-spreading East Pacific Rise. This new technology will allow us to record multi-component seismic reflection and refraction data continuously up to 400 km offset at ~200 m interval, thus opening up a new frontier of research. These new seismic data will provide quantitative P-wave and S-wave velocities of the whole crust, the Moho, the upper mantle and the LAB at unprecedented resolution, which combined with petrological studies will allow us to develop a comprehensive geodynamical model for mantle melting, melt migration, crustal accretion, and lithospheric evolution. The quantitative imaging of structures down to 20-30 km depth on a few hundred metre scale would be a revolution, develop synergy between academic and industrial research, and open up new horizons for deep seismic imaging for upper mantle studies.

Keywords: plate tectonics,mid ocean ridges,oceanic crust,moho,lithosphere asthenosphere boundary,mantle melting,mantle heterogeneities
MULTI-SOURCE AND MULTI-SCALE EARTH OBSERVATION AND NOVEL MACHINE LEARNING METHODS FOR MINERAL EXPLORATION AND MINE SITE MONITORING (MultiMiner)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Finland,Greece,France,Czechia,Austria,Germany
Call: Earth observation technologies for the mining life cycle in support of EU autonomy and transition to a climate-neutral economy (RIA) (HORIZON-CL4-2022-RESILIENCE-01, 2022)
Start date: 2023-01-01
End date: 2026-06-30
Duration (months): 42.0
Total project cost (EUR): 4443096.25
EU funding (EUR): 4443096.25
Participants: 16
Project status: SIGNED

The Multi-source and Multi-scale Earth observation and Novel Machine Learning Methods for Mineral Exploration and Mine Site Monitoring (MultiMiner) project develops novel data processing algorithms for cost-effective utilization of Earth Observation (EO) technologies for mineral exploration and mine site monitoring. MultiMiner unlocks the potential of EO data, including Copernicus, commercial satellites, upcoming missions, airborne and low altitude as well as in situ data, to support the entire mining life cycle including mineral exploration, operational, closure and post-closure stages. This is achieved by creating generic but highly innovative machine learning solutions which do not require any or only little ground truth data. The project focuses on new EO based exploration technologies for critical raw materials (CRM) to increase the probability of finding new sources within EU thereby strengthening the EU autonomy in the area of raw materials. MultiMiner EO based exploration solutions have extremely low environmental impact, and are thus socially acceptable, economically efficient and improve safety. The project’s solutions for mine site monitoring increase the transparency of mining operations as environmental impacts can be detected as early as possible and digital information of the currently unexploitable raw materials can be stored for future generations. The applicability of the developed algorithms is demonstrated in 4 European test sites. MultiMiner is a pan-European consortium consisting of 12 partners and 1 associated partner from research institutes, academia, consulting businesses and mining industry with interdisciplinary backgrounds in geology, remote sensing and machine learning. The members come from six EU member states which represent mining regions across Europe with diverse geology with evident potential for various types of CRM resources and thousands of operational and closed mines.

Keywords: weakly supervised unsupervised methods,multi source eo data,multi scale scalable,novel exploration,continuous monitoring,phosphate rocks,ree,magnesite,antimony
Archaeological Coastal Heritage: Past, present and future of a hidden prehistoric legacy (ArCHe)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway,Spain,Latvia,France,Sweden,Estonia
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 2737461.6
EU funding (EUR): 2737461.6
Participants: 17
Project status: SIGNED

DN ArCHe trains 10 PhD fellows for increasing the scientific and public value of Europe’s archaeological coastal heritage, focusing on the legacy of Stone Age hunter-fisher-gatherers. Including some of the earliest remains of human activity, this legacy is crucial for understanding human engagement with the coast. Yet it is fragile and highly heterogeneous, with diverse material and cultural expressions. It is embedded in a variety of geographic settings across Europe differing in environmental development, which face massive environmental and human threats. It is also approached in various ways in cultural heritage management with little systematic integration of knowledge on the topic. DN ArCHe deals with the challenges of this fractured field with an innovative past-present-future approach which focuses on connecting the legacy from the past, its present status as archaeological heritage and prospects for its future protection and integration. With six beneficiaries and nine associated partners, ArCHe unites academic research centres and non-academic organizations (cultural heritage sector, specialist organisations, museums, media). As a joint platform for research and training, it leverages on customized PhD projects, cross-fertilization of knowledge among researchers and partners, scientific courses, workshops, conferences, applied secondments and transferable skills training. Training in archaeology, anthropology, critical heritage studies, heritage management, bioarchaeology, geology, oceanography, coastal engineering/preservation and communication relevant to coastal heritage and environment, equips ArCHe PhDs with advanced interdisciplinary and cross-regional knowledge and skills applicable to various academic and non-academic fields across Europe. Through best practices, they will contribute to the visibility, preservation and sustainable integration of the vulnerable cultural heritage in coastal areas facing global environmental and development challenges.

Keywords: coastal archaeology,hunter fisher gatherers,global heritage management,cross regionality,stone age,palaeo environment,sea level change,human environment interaction,sustainable development
Novel hybrid electro-anaerobic digestion system for simultaneous antibiotics removal and bioenergy recovery (ElectroAD)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Ireland,Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-08-01
End date: 2026-07-31
Duration (months): 24.0
Total project cost (EUR): 199694.4
EU funding (EUR): 199694.4
Participants: 2
Project status: TERMINATED

The overuse or misuse of antibiotics has caused new pollution challenges and the development of antibiotic bacteria. Anaerobic digestion (AD) is sustainable biotechnology that can couple waste pollution control and bioenergy methane (CH4) recovery. However, AD fails to achieve satisfactory antibiotic removal due to the low concentration and low biodegradability of antibiotics, and the high toxicity of antibiotics on microbial activity. To address these scientific challenges, in this project, we aim to develop a novel hybrid electro-AD system by coupling the application of external voltage and the addition of activated carbon for the enhancement of antibiotic removal and renewable bioenergy recovery. The novel hybrid electro-AD system will synergistically incorporate high adsorption capacity by activated carbon, high biodegradability of antibiotics by bioelectrochemical reduction, and high methanogenic activity mediated by extracellular electron transfer (EET). An excellent array of multidisciplinary methods incorporating electrochemistry, bioinformatics, and molecular biology will be applied to achieve this objective and unravel underlying mechanisms of enhanced EET and antibiotics removal. The results will further create new knowledge of microbial ecological function in AD and advance the application of anaerobic technology to crucial environmental protection scenarios. Combining my background with the training of advanced instruments offered by the host (Dr. Guangxue Wu at NUI Galway) and expertise in quantifying trace compounds from the secondment (Dr. Konrad Koch at TUM), this project will lead to the realization of new anaerobic biotechnology that can achieve simultaneous energy recovery and efficient antibiotic removal, contributing to scientific, societal, and economic impacts. Being an independent investigator of this project, this fellowship will provide an excellent chance for me to become an independent research group leader in my future career.

Keywords: antibiotics,methanogenesis,anaerobic digestion,bioelectrochemistry
Towards sustainable Computational Fluid Dynamics (FairCFD)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France,Greece,United Kingdom,Germany,Spain,Italy,Sweden,Belgium
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 4678982.64
EU funding (EUR): 4555322.64
Participants: 18
Project status: SIGNED

FairCFD aims to transform Computational Fluid Dynamics (CFD) by promoting eco-responsible and efficient numerical methods through a cutting-edge doctoral network. Fully aligned with the European Green Deal and MSCA Green Charter, it embeds sustainability into High-Performance Computing (HPC) while advancing methodologies to reduce environmental impact. The project brings together 8 European universities, one national research center, and 6 industrial partners to train 15 Doctoral Candidates (DCs) in interdisciplinary approaches combining computational science, environmental engineering, and social sciences. Fourteen DCs will address industrially relevant challenges, advancing technological innovation, while one will provide an ethnographic perspective on the network’s practices. The program emphasizes excellence in doctoral training through international secondments, interdisciplinary collaboration, and exposure to academic and industrial environments. This prepares DCs with the skills to meet evolving market needs while strengthening Europe’s innovation capacity and structuring doctoral research at the European level. This aligns with market demands for experts capable of balancing computational performance and with sustainability in sectors like energy, transportation, and aerodynamics. By improving numerical efficiency, fostering frugality, and developing transparent metrics, FairCFD supports industries and research institutions in meeting future sustainability goals. FairCFD will deliver innovative efficient simulation methods combining physics and data, metrics to quantify environmental costs, and open-source tools, ensuring wide dissemination and impact. The project positions Europe as a leader in eco-responsible scientific computing and sets a benchmark for sustainability-focused doctoral education.

Keywords: computational fluid dynamics
Next-gen fluorescence imaging for research and theranostics (TriScanner)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Belgium
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2023-06-01
End date: 2024-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Fluorescence microscopy is key technique in the life sciences, though the method struggles to deliver the fast and sensitive imaging of multicellular systems. Such samples are now becoming commonplace not only in research but also in clinical use, including spatially-resolved 'omics' and theranostics based on patient material that allow the development of personalized treatments. However, their general uptake is limited by the absence of suitable instrumentation. As part of our ERC-funded research, we have invented the TriScanner, a novel fluorescence microscope that offers transformative imaging performance (much faster imaging, higher resolution, higher sensitivity), and is also simple, robust, and affordable. Our TriScanner readily addresses an urgent need in current research and healthcare research, and is well-positioned to scale out from research into 'workhorse' usage in industrial R&D and diagnostics. We propose to develop this idea from a concept and lab prototype into a robust demonstrator that is showcased on a variety of highly-relevant applications, and that we will leverage to raise user awareness and interact with key leaders in academia and leading commercial partners. This project will furthermore allow us to explore the business case and market potential, in view of developing and selecting the optimal valorization track. We expect to deliver societal impact by providing unprecedented new imaging capabilities in a fast-moving and highly influential research field.