Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Rendering 3D images with attributes learned from 2D images via Deep Learning (3DIS-NN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Türkiye
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-03-01
End date: 2023-02-28
Duration (months): 24.0
Total project cost (EUR): 145355.52
EU funding (EUR): 145355.52
Participants: 1
Project status: CLOSED

3D (3-dimensional) Image Synthesis (3DIS) is a technology to render objects from different views which enables numerous applications in computer graphics and computer vision. As the digital world is becoming more crucial especially in the times of pandemic, 3DIS can provide tools for online classes, virtual social tours, improved gaming experience and simulators for robotics by providing realistic virtual 3D environments. Furthermore, 3DIS by disentangling the attributes of objects and entangling them via a renderer for synthesize, can provide a technology to learn useful features from our visual world that can be used for video understanding, one of the biggest goals of artificial intelligence. Here, I propose 3DIS-NN, a set of methods to improve the quality of 3DIS with deep neural networks (DNNs), and bring it close to the production quality, which will contribute to the European Union’s Future and Emerging Technology ambitions of Horizon Europe. Learning 3DIS from 2D images with deep learning is a challenging topic due to its inherent ambiguity. 3DIS-NN will enable high-quality 3DIS results by i) creating a dataset with weak labels to feed the data-hungry DNNs for better accuracy, ii) improving robustness of 3D geometry and texture prediction from images, iii) handling the impurities in segmentation of objects with a novel design of architecture, and iv) providing a tool to further close the domain gap in renderers and real images. This interdisciplinary proposal which is at the intersection of deep learning and computer graphics will be carried out at under the supervision of Prof. Ugur Gudukbay who is an expert in computer graphics. In terms of career developments, this proposal will consolidate and accelerate my career on the international landscape scene as a pioneer lead authority in the new cross-disciplinary area of “deep learning & computer graphics”.

Keywords: learning 3d rendering from 2d images
Novel bi-lamellar lipid vesicles for studying double-membrane transenvelope proteins (BiLamVesicles)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-08-01
End date: 2022-07-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

Double membranes are ubiquitous throughout the domains of life, accommodating remarkable protein machineries which are fundamental to the cellular activity. However, the study of these proteins is restricted by the lack of a suitable membrane model to accommodate them. Within the framework of BiLamVesicles I will develop a novel bi-lamellar lipid vesicle as a tool for hosting and studying proteins which naturally span across double membranes such as the nucleus and Gram-negative bacteria envelopes. To integrate the protein of choice within the vesicle envelope I will design and employ a highly regulated layer-by-layer assembly in a microfluidic chip. This approach will combine the host’s expertise in microfluidics and biophysics with my expertise in surface interactions and surface chemistry to allow an exquisite control over the membrane composition of bi-lamellar vesicles and the protein insertion process. Once assembled, I will use these vesicles to study the activity of the entire Gram-negative bacterial transporter system AcrAB-TolC, an archetype multidrug efflux pump of Escherichia coli. I will spatially isolate vesicles in a microfluidic chip and directly quantify transport rates through a full efflux pump system at the single-vesicle-level for the first time, using an advanced optofluidic system. The synergy between microfluidics and the proposed double membrane vesicles will produce a ground-breaking biotechnological technique for studying the activity of as yet inaccessible proteins in a biologically-relevant environment. This research will stretch the existing boundaries set by current membrane models and will pave the way for developing advanced techniques for drug screening assays.

Keywords: bi lamellar lipid vesicles,microfluidics,protein reconstitution,multidrug efflux pump,active transport
Operational Platform managing a fleet of semi-autonomous drones exploiting GNSS high Accuracy and Authentication to improve Security & Safety in port areas (PASSport)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Innovation actions
Countries involved: Italy,Germany,Spain,Italy,Italy,Germany,Spain,Spain,Italy,Poland,Belgium,Croatia,France
Call: EGNSS applications fostering green, safe and smart mobility (H2020-SPACE-EGNSS-2020, 2020)
Start date: 2020-12-01
End date: 2023-11-30
Duration (months): 36.0
Total project cost (EUR): 3686222.5
EU funding (EUR): 2868239.9
Participants: 16
Project status: SIGNED

The purpose of the PASSport (Operational Platform managing a fleet of semi-autonomous drones exploiting GNSS high Accuracy and Authentication to improve Security & Safety in port areas) is to engineer and qualify a solution extending situational awareness based on aerial fixed/ rotary wing and underwater drones to improve safety and security in port areas. The need stems from the directive 2005/65/CE asking to complement surveillance systems for the whole port area, in order to significantly improve security and safety for daily operations implanted in port area. This result also in saving citizen lives ensuring a high and equal level of safety and security for all European ports. Around one thousand European ports fall within the scope of the directive. As a consequence, PASSport responds to the needs expressed by port authorities, harbour master and border control authorities which are active parties in the consortium and will be directly involved in the definition of the proposed solutions. The proposed solution is intended to complement already operational platforms by extending the surveillance perimeter using a fleet of drones to provide innovation and operational support to the recognition, management and analysis of safety and security aspects of daily operations with particular attention to: Pollution monitoring (safety) Support to e-navigation (safety) Critical buildings/ Infrastructures protection (security) Protection against non-cooperative small craft approaching the port areas (security) Underwater threats monitoring (security) The project is expected to activate commercialisation channels based on the novelty represented by the usage of a fleet of semi-automated drones integrating Galileo services (and other sensors) for a safe and efficient guidance, navigation and control (GNC) even in a challenging environment in presence of obstacles - including buildings and other ground assets - and potentially unfavourable weather conditions.

Keywords: egnss,drones,port operations,citizens protection,safety,security,regulations
Microbial invasion and dissemination within the host, mechanisms and effects (INVADIS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: France
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-11-01
End date: 2024-04-30
Duration (months): 90.0
Total project cost (EUR): 2750000.0
EU funding (EUR): 2750000.0
Participants: 1
Project status: SIGNED

An infection is defined by the deleterious consequences of the interactions between a pathogen and a host. Thus, studying the biology of infection reveals critical properties of hosts and pathogens, and is a way forward to address basic biological questions and improve health. We study listeriosis, a systemic infection caused by Listeria monocytogenes (Lm). Lm is a human foodborne pathogen that crosses the intestinal barrier, disseminates systemically, replicates in liver and spleen and reaches the central nervous system (CNS) and fetoplacental unit. Given the remarkable journey Lm makes in its host, studying listeriosis offers unprecedented opportunities to understand host cell biology, physiology and immune responses, guided by Lm. The mucosal, CNS and fetoplacental tropisms of Lm are shared by other microbes which pathogenesis is far less understood. Lm therefore stands as a unique model microorganism of general biological and medical significance. The major challenge of this project is to go beyond reductionist approaches and embrace the complexity of actual infections. We will use stem cell-derived organoids, live imaging, genetically engineered mouse models, the clinical and biological data from a unique cohort of 900 patients and the corresponding causative Lm strains, to investigate the molecular mechanisms of Lm tissue invasion, dissemination and host responses. Specifically, we will (i) decipher the cell biology of microbial translocation across the intestinal epithelium; (ii) study the impact of microbial portal of entry on microbial fate, dissemination and host responses; (iii) harness Lm biodiversity to identify novel virulence factors and (iv) discover new host factors predisposing to invasive infections. Building on the unique combination of advanced experimental systems and exclusive clinical data, this integrative and innovative project will reveal novel, physiologically relevant mechanisms of infection, with scientific and biomedical implications.

Keywords: infection,barrier,pathophysiology,bacteria,epithelial,cell,tissue,in vivo,animal models,imaging,human host
(EU) Explorations in Next Generation Internet emerging research opportunities, technOlogies and methods. (EU Engineroom)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Coordination and support actions
Countries involved: Spain,Poland,United Kingdom
Call: Next Generation Internet (H2020-ICT-2017-1, 2017)
Start date: 2017-10-01
End date: 2019-03-31
Duration (months): 18.0
Total project cost (EUR): 692375.0
EU funding (EUR): 692375.0
Participants: 3
Project status: CLOSED

No other technology has been able to radically reshape and permeate the very fabrics of our societies as rapidly and fundamentally as the internet has. But the increased concentration of power on the internet in the hands of just a few ever more dominant players makes that few now reap the true benefits of the digital economy; the growing complexity and opacity of the processes and technologies that govern it makes challenging this status quo exceedingly difficult. Serious interventions are needed to make the next generation internet inclusive, resilient and competitive again. By intervening in the development process of emerging technologies, we are able to steer the process of innovation in a human-centric and ethical direction and allow European businesses and civil society organisations to play a leading and pioneering role in their development. But to help direct and shape the future internet, we need to know which technologies will underpin it. To identify the technologies that will likely be game changers for the internet in 2025, we use cutting edge big data methodologies and novel web-scraped data sources to capture early signals about technologies and research topics, and develop a rigorous process for evaluating whether a technology will positively contribute to the development of a more desirable internet. The EU Engineroom project approach is centred around the articulation of an ambitious and concrete vision for the future internet, and the development of a methodology for identifying those technologies and research topics that will underpin that vision of a more inclusive, resilient and competitive internet by 2025. This methodology will form a key pillar for future phases of the NGI initiative as an easily-reproducible and comprehensive tool for continuously identifying and evaluating emerging technologies and trends, and helps establish the NGI as a key new flagship programme for internet research beyond Horizon2020.

Keywords: big data methodologies,futures,innovation mapping,research,experimentation,agenda setting,key enabling technologies
'If immortality unveil…'– development of the novel types of energy storage systems with excellent long-term performance (IMMOCAP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Poland
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2017-10-01
End date: 2023-09-30
Duration (months): 72.0
Total project cost (EUR): 1385000.0
EU funding (EUR): 1385000.0
Participants: 1
Project status: SIGNED

The major goal of the project is to develop a novel type of an electrochemical capacitor with high specific power (up to 5 kW/kg) and energy (up to 20 Wh/kg) preserved along at least 50 000 cycles. Thus, completion of the project will result in remarkable enhancement of specific energy, power and life time of modern electrochemical capacitors. Advanced electrochemical testing (galvanostatic cycling with constant power loads, electrochemical impedance spectroscopy, accelerated aging and kinetic tests) will be accompanied by materials design and detailed characterization. Moreover, the project aims at the implementation of novel concepts of the electrolytes and designing of new operando technique for capacitor characterization. All these efforts aim at the development of sustainable and efficient energy conversion and storage system.

Keywords: electrochemical capacitors,energy conversion and storage,highly porous carbon materials
A Breast Cancer Biomarker Point of CarePOCDiagnostic Platform Integrating Dual-Functionalized Nanoparticle for Magnetic Gradient Ranking and Electrochemical Sensing (Biochip-images)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-12-01
End date: 2022-05-31
Duration (months): 24.0
Total project cost (EUR): 184590.72
EU funding (EUR): 184590.72
Participants: 1
Project status: CLOSED

Breast cancer is the most common neoplasm in women and the second leading cause of cancer-related mortality in females worldwide, with 25.1% of incidence and 14.7% of mortality across all cancers. A convenient blood-based tumor marker test has the potential to underpin a significant improvement in early intervention. In this context, this proposal is concerned with development of a new point of care (POC) device for biomarker detection by exploiting a combination of state of the art magnetophoresis, electroanalysis, nanotechnology, and microfluidic integration. In the POC device, dual-functionalized magnetic nanoparticles (dual-NPs) with antibodies and redox probes will be capable of selectively recruiting specific markers from real patient samples and will additionally underpin amplified redox probes for detection. Second, using a magnetic gradient chip, composed of both magnetic gradient (Mag) and microelectrode (Me) arrays, the exerted magnetic gradient field will be capable of separating dual-NPs labeling biomarkers (MBs) from free dual-NPs (MPs) to be positioned at distinct sensing zone of micro-electrode, prior to assay. Herein, only those biomarkers hosted by dual-NPs, will be reported electrochemically for quantification. Three primary objectives are proposed by the candidate: i) development of dual-NPs combining immunological recognition and electrochemical amplification properties, ii) fabrication of Mag chip engineering Mag and Me arrays for magnetic gradient ranking and electrochemical sensing, iii) integration of POC platform with Mag and Me arrays, dual-NPs and microchannels, for cancer biomarker diagnosis. As a proof-of-concept, the developed POC device will be applied to the detection and quantification of breast cancer markers (CA15-3, PAI-1 and HSP90A) in a small (<20µL) blood serum. The detection limit of this device is expected to be ng/ml quantities and duration is estimated to 15 mins for each test with blood serum.

Keywords: magnetic nps,magnetic gradient magnetophoresis,electrochemical sensing,microfluidics,cancer biomarkers
How musical rhythm moves humans: functional mechanisms of entrainment and perception-action coupling (Rhythm and Brains)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Belgium
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-04-01
End date: 2025-03-31
Duration (months): 72.0
Total project cost (EUR): 1494900.0
EU funding (EUR): 1494900.0
Participants: 1
Project status: SIGNED

Entrainment to music is a culturally widespread activity with increasingly recognized pro-social and therapeutic effects. Music powerfully compels us to move to the musical rhythm, showcasing the remarkable ability of humans to perceive and produce rhythmic inputs. However, the underlying functional mechanisms remain unknown. One view, which dates back to Darwin, is that the relevant mechanisms are ancient and anchored in the evolutionary oldest subcortical parts of the brain. However, recent research argues that rhythm perception is a complex cognitive function involving temporally precise communication between cortical sensory and motor regions, even in the absence of overt body movement or intention to move. This project aims to uncover these mechanisms by combining concepts and methods of experimental psychology and cognitive neuroscience. Specifically, the research will (i) unravel the mechanisms at the interface of rhythmic inputs, motor skills and brain activity, (ii) establish the active role of motor representations in rhythm perception, (iii) track the development of these processes even prior to language in infants, and (iv) investigate the physiopathology and restoration of these processes in brain-damaged patients. To achieve these objectives, the project will use a comparable method across different experimental settings, the frequency-tagging approach, whose reliability and advantages have been recently established as an innovative method to capture neural entrainment to rhythm in humans. Results will provide important knowledge into how psychological, environmental and neural mechanisms affect such entrainment. Clarifying these mechanisms provides an optimal framework to unravel the role of an intrinsic sensory-motor coupling underlying perception and how this coupling develops over the lifespan. It is also critical for optimising clinical rehabilitation practices using music as a powerful non-verbal cross-cultural means of communication.

Keywords: electroencephalography,frequency tagging,human intracranial recordings,music cognition,rhythm perception,sensorimotor synchronization
Collaborative, Decision making, and Operational Shared-Control Framework for Human-Robot Interaction (HRI-CoDeOp)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-11-09
End date: 2024-11-08
Duration (months): 36.0
Total project cost (EUR): 246669.12
EU funding (EUR): 246669.12
Participants: 2
Project status: CLOSED

The overall aim of of the planned research is to develop a holistic, human-centric shared-control framework for human-robot collaboration that will consider the interaction on: (i) the cognitive/decision-making level for a dynamic allocation of responsibilities and roles to the human and the robot, as well as an online negotiation to avoid/resolve conflicts, and (ii) the physical/operational level with human-in-the-loop. Currently, there exists no holistic shared-control framework that enables interaction on cognitive (decision-making) and operational (physical) levels simultaneously, that is independent of the type of a robot system or the interaction (teleoperation or direct physical interaction). The shared-control framework that will be developed within this project will enable human-robot collaboration in many application domains ranging from industrial, service, medical, to exploration of dangerous/inaccessible environments. In particular, the Covid-19 pandemic has revealed a pressing need for robot assistants in hospitals because of a shortage of clinical professionals and the risk of infection spreading to hospital staff who interact with infected patients. Therefore, the focus of this action is on human-robot collaboration in healthcare.

Keywords: human robot interaction,shared control,human decision making,human motor control,teleoperation,haptics