Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Large-scale Simulations for Disorder-driven Orbital Transport (LASIDO)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Research and Innovation actions
Countries involved: France,Portugal
Call: Hop on Facility (HORIZON-WIDERA-2023-ACCESS-06, 2023)
Duration (months): 36.0
Total project cost (EUR): 271625.0
EU funding (EUR): 271625.0
Participants: 2
Project status: CLOSED

The latest progress in orbitronics research raises new questions on orbital transport phenomena driven by disorder, including diffusion, relaxation, and extrinsic Hall effect. LASIDO aims to conduct large-scale simulations in real space to determine the mechanisms responsible for the diffusion and relaxation of the orbital moment in model and realistic systems. It will also explore new routes to maximize the interconversion between charge currents and orbital currents by disorder engineering in low-Z materials. With a close connection with the experimental program developed by the EIC Pathfinder Open OBELIX, these endeavors will open novel avenues for the realization of energy-efficient orbital-based devices.

Keywords: spintronics,nano electronics,mesoscopic physics,materials science
Computational multiplexing to optimise next-generation sequencing (MultiSeq)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2023-12-01
End date: 2025-05-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 2
Project status: CLOSED

Recent advances in Next-Generation Sequencing (NGS) of nucleic acids (i.e. DNA or RNA) have transformed biology and medicine. Today NGS is one of the main pillars of research in various biological disciplines, and it has already pervaded numerous fields of applications ranging from clinics to the biotechnological industry. Given its versatility and high demand, the global market for NGS is rapidly expanding, with the number of sequenced samples doubling every two years. However, while major advances in NGS were mainly related to a rapid increase in sequencing throughput per machine, the preparation of sequencing libraries - the other integral step of NGS, has largely remained unchanged. Currently, this step is the major financial and operational bottleneck for sequencing projects, limiting the widespread adoption and utility of NGS. Current state-of-the-art solutions for overcoming these problems either require high upfront costs and/or are laborious. We are developing a bioinformatics solution to these problems, which minimizes the cost and time of library preparation. Our approach, called MultiSeq, allows designing a multiplexing strategy to reduce the number of libraries followed by computational demultiplexing. We plan to extend the experimental proof of concept of our method by applying it to broadly sequenced species. In addition, we will integrate our algorithms into a versatile computing framework and develop a pilot project in an industrially relevant context. In parallel, we will perform market analysis and evaluate the most suitable IP protection and commercialization strategies of our technology. If successful, MultiSeq will be a game-changing approach that will impact sequencing technology and related industries by further democratizing the field of NGS and benefiting both the scientific community and society.
Multi-Dimensional Resource Management for 6G IoT Networks with Generative Artificial Intelligence (Multi-RM-6GIoT-GAI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-05-01
End date: 2028-04-30
Duration (months): 24.0
Total project cost (EUR): 236340.0
EU funding (EUR): 236340.0
Participants: 1
Project status: SIGNED

The Internet of Things (IoT) has fundamentally changed our interaction with the physical world, bringing a paradigm shift that has transitioned physical objects into digital and interconnected devices. This digitalization revolution largely hinges on to take a significant leap forward with the deployment of emerging 6G networks. While 6G holds great promise, it also poses severe challenges, especially in dynamically managing its vast multi-dimension resources amid heightened demands for latency, rates, reliability etc. Traditional approaches, particularly those relying on Deep Reinforcement Learning (DRL), have obvious limitations in various and complex 6G IoT networks. In this context, we will explore Generative Artificial Intelligence (GAI) to solve these challenges. First, we will establish a hypergraph-based framework for multi-dimensional resource representation and modeling, targeting the optimization of service capabilities. Subsequently, we will use the Generative Diffusion Model (GDM) to streamline communication intent extraction, facilitating swift decision-making and improving the adaptability of the network. Finally, we will leverage GDM in crafting resilient incentive structures, aiming to ensure the fairness of resource distribution and enhance user experience in the 6G IoT environment. The project has three work packages (WPs): WP1 aims at designing measurements for multi-dimensional resources, WP2 investigates the utilization of GDM for adaptive resource management, and in WP3, we seek to use GDM to ensure fairness in resource sharing. By integrating GAI as a solution to the multifaceted challenges of 6G IoT, we seek to expand and redefine the capabilities and applications of 6G IoT in real-world contexts.

Keywords: 6g iot,multi dimensional resource management,urllc,hypergraph,generative artificial intelligence
Next Generation Chiral Fluorine Groups for Molecular Design (ChiroFluor)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-04-01
End date: 2025-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Fluorinated motifs have enormous societal relevance due to their ubiquity across the pharmaceutical, agrochemical and materials science sectors. These essential structural components feature prominently in the World Health Organization’s (WHO) list of essential medicines, and contribute to global food supplies by optimising the performance of many key agrochemicals. Similarly, our reliance on (polyfluorinated) materials ranging from non-stick Teflon® through to smart materials underscores the versatility of fluorinated groups in functional small molecule design. The historic success of fluorinated groups in societally-important molecules, coupled with scarcity of organofluorine building blocks in nature, continues to create a powerful impetus to develop more efficient and sustainable methods to facilitate their construction. However, the environmental impact of perfluorinated materials has come under scrutiny due to the persistence of the materials in the environment. The recent proposal by the European Parliament to address the persistence of perfluoroalkyl and polyfluoroalkyl (PFAS-type molecules) in water supplies covers "any substance that contains at least one fully fluorinated methyl (CF3) or methylene (CF2) without any H, Cl, Br, or I attached to it." Fluorinated groups that simultaneously conform to new legislative guidance, no longer pose an environmental threat and open up new areas of space for discovery will be generated efficiently. Through the intervention of ChiroFluor, unique structural entities such as the BITE group will be forged in both enantiomeric forms (handedness) to push chemical space beyond the existing boundaries. This project will simultaneously address a pressing environmental and legislative issue in a sustainable manner using an organocatalytic I(I)/I(III) platform based on data generated in ERC Consolidator RECON (818949), and validated with key industrial partners.
Invigorating Enlargement and Neighbourhood Policy for a Resilient Europe (InvigoratEU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Democracy and Governance
Action type: Research and Innovation actions
Countries involved: Germany,North Macedonia,Moldova, Republic of,Montenegro,Serbia,Ukraine,Belgium,Finland,Italy,Latvia,Lithuania,Poland,Spain,Netherlands,Switzerland,Georgia
Call: Political perspectives for the Eastern Neighbourhood and the Western Balkans (HORIZON-CL2-2023-DEMOCRACY-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 2996577.5
EU funding (EUR): 2996577.5
Participants: 19
Project status: SIGNED

“HOW CAN THE EU INVIGORATE ITS ENLARGEMENT AND NEIGHBOURHOOD POLICY TO ENHANCE EUROPE’S RESILIENCE?”. InvigoratEU aims at finding answers to this question by pursuing three overarching goals: Our first goal is (1) to investigate HOW TO REFORM the EU’s enlargement strategy in a new geopolitical phase, HOW TO RESPOND to other actors’ geopolitical ambitions in the Eastern Neighbourhood and Western Balkans, and HOW TO REBUILD the EU’s foreign policy arsenal in view of a new era of military threats (triple “R” approach) combining the modernisation and geopolitical logics of EU enlargement, leading to new data – e.g. a public opinion survey in Ukraine, a set of scenarios, an external influence index (Russia, China, Turkey), and a social policy compliance and cohesion scoreboard. Our second goal is (2) to elaborate an EVIDENCE-BASED, FORWARD-LOOKING VISION FOR THE EU’s POLITICAL AGENDA AND INSTITUTIONAL FRAMEWORKS FOR CO-DESIGNING A MULTIDIMENSIONAL TOOLBOX (i.e. two tailor-made toolkits), together with InvigoratEU´s Expert Hub, Civil Society (CS) Network, Youth Labs, Workshops for Young Professionals and Policy Debates in a gaming set up, which will result in context-sensitive and actionable policy recommendations for European and national political stakeholders and (young) European citizens in particular. Our third goal is (3) to deploy a CDE (communication, dissemination and exploitation) strategy AIMING AT RECOMMENDATIONS FROM DAY 1 to maximize our scientific, policy and societal impact in invigorating the EU´s enlargement and neighbourhood policies to enhance Europe´s resilience. ULTIMATELY, INVIGORATEU IS A DELIBERATELY LARGE CONSORTIUM respecting THE DIVERSITY OF EUROPE and POLITICAL PERSPECTIVES; 7 out of 18 are from GEORGIA, MOLDOVA, UKRAINE, and the Western Balkans (NORTH MACEDONIA, MONTENEGRO, SERBIA), COMPLEMENTED BY our CS Network of 9 representatives from all Western Balkan countries, Georgia, Moldova and Ukraine.

Keywords: strategic foresight enlargement policy civil society enagement
Boosting the Industrial Uptake of Biodegradable polymers for packaging applications by implementing digital tools and advanced techniques to achieve a holistic sustainability goal (Be-UP)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Innovation actions
Countries involved: Spain,Netherlands,Croatia,Cyprus,Germany,Belgium,Italy,France,Slovenia
Call: Biodegradable polymers for sustainable packaging materials (IA) (HORIZON-CL4-2024-RESILIENCE-01-TWO-STAGE, 2024)
Start date: 2025-05-01
End date: 2029-04-30
Duration (months): 48.0
Total project cost (EUR): 8428727.5
EU funding (EUR): 6725451.64
Participants: 17
Project status: SIGNED

Within Be-UP project new synthesis and processing routes will be developed for novel aliphatic-aromatic biopolyesters with increased renewable content using biobased building blocks (e.g 1,4 bio-BDO), alongside innovative catalysts and additives. These components will be optimized through advanced digital modelling tools, based on Kinetic Monte Carlo (kMC) models, for synthesis and polymerization. These biopolyesters will be blended with commercial biopolymers (e.g., PLA, PBAT, and PHA), biobased chain extenders, and mineral fillers to create bioplastic packaging materials. The design of these blends will employ advanced compounding modelling tools, supported by techniques like screw design and inline rheology measurements, to achieve the target technical performance, sustainability and biodegradation goals using multi-objective function evaluation. Processability will be also a key factor, with a focus on the primary production techniques used in the packaging industry, namely, blown film extrusion, injection moulding and thermoforming. A set of packaging products’ prototypes (TRL7) will be manufactured to validate the developed materials. The biodegradability of these novel products will be assessed in different End-of-life (EoL) scenarios, including open environments and controlled conditions, thus making possible to fill the gap between laboratory conditions and real end-of-life behaviour of these materials. Additionally, the recyclability of the new products will be evaluated. The data and conclusions of these assessments will be useful for: i) the development of guidelines and tools for circular design contributing to the adoption of the Safe and Sustainable by Design (SSbD) Framework; ii) contributing to improve the standardization framework for testing and labelling of materials and packaging products. Be-UP is expected to replace more than 50,000 tonnes in 2032 of non-biodegradable plastics leading to savings of over 120,000 CO2 eq tonnes yearly.

Keywords: plastics processingandrecycling,bioplastics,bioplastics engineering,biodegradation,laboratory biodegradation,natural environment biodegradation,digital engineering and modelling,stakeholders engagement
Eco-friendly and bioinspired protein-based synthesis of magnetic nanomaterials for advanced cancer theranostics (ProteNano-MAG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,France,Germany
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-06-01
End date: 2026-05-31
Duration (months): 36.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 3
Project status: TERMINATED

The key goals of “ProteNano-MAG” are: (a) the training of a talented researcher, Dr. Lourdes Marcano, in the fast-growing field of science, technology and industrial applications of nanomedicine, where the host and partner institutions have critical knowledge and expertise; and, (b) the design, development and optimisation of eco-friendly synthesis routes using bioinspired simplified engineered proteins as templates for the preparation of magnetic nanoparticles for effective diagnosis and therapeutic intervention in cancer treatment. The interdisciplinary training program includes protein engineering, preparation of magnetic nanomaterials, characterization including sophisticated synchrotron-related techniques, in-vitro studies, magnetic resonance imaging and implementation for hyperthermia applications. The fellow is a talented researcher who has gained much expertise in biological synthesis mediated by magnetotactic bacteria (natural systems which are inspiration to “ProteNano-MAG”) and structural and magnetic characterization of single-domain magnetic nanoparticles during her undergraduate and postgraduate career. To further boost her career, she needs to gain expertise in alternative routes for the preparation of magnetic nanomaterials, design and characterization of recombinant simplified protein systems and state-of-the-art techniques such as space-resolved X-ray fluorescence and absorption spectroscopies, fields in which the CIC biomaGUNE and the two secondment’ co-hosts, the ESRF and the Universität Bayreuth, have a world-recognised expertise. Additionally, through the six-month placement at Resonant Circuits Ltd., the fellow will gain additional high-level training in magnetic hyperthermia for the medical/industrial application of the prepared magnetic nanoparticles. This multidisciplinary project will also increase her supervision experience, project and intellectual property management expertise, and research funding and proposal writing skills.

Keywords: bioinspired synthesis of nanomaterials magnetic nanoparticles protein engineering magnetic and structural characterization synchrotron techniques nano xrf nano xanes mri magnetic hyperthermia
Mesh-electronics for next-generation skin tissue engineering (BioKIN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: SIGNED

The BioKIN project aims to engineer a biomimetic in vitro platform for the non-destructive, remote, and real-time monitoring of laboratory-grown skin. The project is focused on developing a seamless device to interface with bioengineered skin tissue. Strategies will be established to integrate the device with skin cells to mature hybrid functional skin, where electronics and tissue grow alike. The obtained hybrid functional tissue will provide a powerful tool to study skin biological processes, which will be used early by monitoring wound healing in vitro. Every year, over 50 million patients suffer from severe skin injuries such as burns and chronic wounds and need effective therapies to restore skin function. Fueled by this need, researchers have developed advanced skin substitutes for skin regeneration and replacement by tissue engineering techniques. Despite the incremental improvement of bioengineered skin and its use to regenerate damaged injuries, in situ, non-destructive, and real-time monitoring of their performance has not been sufficiently addressed. BioKIN will equip bioengineered skin tissue with advanced, non-biological capabilities, thus providing a promising platform that supports the understanding of epidermal biology, tissue formation, and skin diseases. The multidisciplinary skills gained during this action BioKIN will significantly enhance the applicant’s future career prospects in bringing bioelectronics to skin tissue engineering.

Keywords: bioelectronics,electronic biointegration,skin tissue engineering,cell electronics interface,tissue electronics interface,biomimetic devices,skin substitutes,mesh electronics,nanotechnology
Carbon-Based Materials Development for Sulfur Cathodes and High-Capacity Lithiated Silicon Anodes in LiSi-S Batteries (SALSA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Ireland,Czechia
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-06-03
End date: 2026-06-02
Duration (months): 24.0
Total project cost (EUR): 199694.4
EU funding (EUR): 199694.4
Participants: 2
Project status: SIGNED

The reduction of global warming, decreasing emissions from combustion engines, and sustainable energy are the imperatives of our times. Thus, the demand for high-energy density batteries is increasing in an effort to accelerate global electrification. Currently, electric vehicles (EVs) rely on lithium-ion (Li-ion) batteries, however, there is an urgent requirement for longer range EVs that can truly displace combustion engines. To do this, an increase in battery energy density and cycle life is sought by developing materials with improved capacity compared to commercial materials. A promising alternative to Li-ion technologies are lithium-sulphur (Li-S) batteries thanks to their high theoretical capacity. However, pure Li metal anode in Li-S batteries may be a potential safety risk due to the formation of Li dendrites which may result in an internal short-circuit. Alternative anode materials may eliminate this issue; among all the anodes, Si-based candidates show one of the highest theoretical capacities. The application of lithiated Si and S as the anode and cathode (LiSi-S) has not yet shown high capacity and viability due to a lack of material investigation. The goal of this project is to develop a novel S cathode, lithiated Si anode and assemble a LiSi-S battery with a capacity of at least 600 mAh/g and a cycle life of >500 cycles. The anode will be based on Si nanowires in order to mitigate the volumetric expansion during cycling. The cathode will have incorporated S in highly porous material to improve the cycle stability and suppress electrode material damage during cycling. All materials used will satisfy conditions of sustainability, low-cost, and safety. The ambitious project will be conducted in three different research groups in Ireland, Czechia, and Slovakia. This prestigious fellowship will provide a platform of renowned subject experts, and exposure to international collaborators will provide a unique opportunity to grow as an independent researcher.

Keywords: next generation batteries sulphur cathode silicon anode
cryogenic Vibration Isolation enabling Low Temperature Scanning Probe Microscopy in cryogen-free dilution refrigerators (cVIS-QM)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: other EIC
Destination: Other destinations
Action type: Coordination and support actions
Countries involved: Netherlands
Call: EIC Booster grant for EIC Pathfinder and EIC Transition grants (HORIZON-EIC-2024-BOOSTER-IBA-01, 2024)
Start date: 2024-11-01
End date: 2025-07-31
Duration (months): 9.0
Total project cost (EUR): 71355.71
EU funding (EUR): 49949.0
Participants: 2
Project status: CLOSED

The Project QuCoM (101046973) is developing a new product that is obviously innovative and easily appreciated advantages to customer. The product is a multi-stage mass-spring system for passive reduction of vibration noise, equipped with heat links and tailored to the requirements of applications working in a cryo-environment. The transfer function of the mass-spring system is engineered to reflect the cryostat vibrations. The heat links are engineered to preserve the cooling power at the experimental stage as well as the mechanical transfer function of the filter. The concept of the technology has been proved, but further development and improvement of key performance parameters is needed before exploitation. Moreover, a more detailed market study and better understanding of end user needs, as well as formulating a mature business case is needed. In this Booster project we propose to do a more detailed market study and formulating a business case for the use of cryogenic Vibration Isolation Systems (cVIS) in the field of Scanning Probe Microscopy at cryogenic temperatures.

Keywords: vibration isolation,low temperature,cryogen free,quantum metrology,quantum sensing