Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Asymmetric Chlorofunctionalization of Activated carbon-carbon Double bonds (ACAD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2011-IOF, 2011)
Start date: 2012-04-01
End date: 2014-10-15
Duration (months): 30.0
Total project cost (EUR): 221173.05
EU funding (EUR): 221173.05
Participants: 1
Project status: CLOSED

In collaboration with Prof. S. E. Denmark and Prof. E. M. Carreira the researcher will work with two of the world’s leaders in organic chemistry in the complementary areas of methodology development and natural product synthesis, respectively. In the outgoing phase a novel, asymmetric, Lewis base activated, Lewis acid catalysed reaction will be developed to allow for the asymmetric chlorofuntionalization of activated carbon-carbon double bonds. This objective will be achieved through the thorough screening of reaction profile with respect to Lewis acid, Lewis base, electrophile and trapping agent and through the analysis of reaction kinetics using techniques such as ReactIR and rapid-injection NMR spectroscopy. The Denmark group’s experience in this area, built up over the last 15 years, will allow for efficient iteration and optimisation of the protocol. In the return phase application of the developed methodology towards the synthesis of the chlorosulfolipid family of natural products is planned, along with the transferring of the obtained knowledge/skills to European researchers. Specifically, this will be achieved through the mentoring of junior students. The proposed research and research plan is specifically designed to test and develop the researchers leadership qualities and ability for independent study as well as to provide experience and knowledge in an area of increasing importance. The ultimate ambition of the researcher is to obtain and sustain a successful, independent academic position in a European institution. With this in mind the proposed research represents an excellent career development opportunity. This proposal will initially raise the profile of European research and, through the training of the next generation of European researchers during the return phase, increase the competitiveness of European science.

Keywords: physical sciences,chemistry,organic chemistry,asymmetric catalysis
The Physiological Control of Stem Cells: Obesity, Insulin, and Neural Stem Cell Dynamics. (OBINNSC1)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Sweden
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2013-07-01
End date: 2015-10-05
Duration (months): 24.0
Total project cost (EUR): 181418.4
EU funding (EUR): 181418.4
Participants: 1
Project status: CLOSED

Stem cells are essential to the homeostasis, repair, and function of the tissues in which they reside. Stem cells can be regulated by systemic endocrine signals, meaning environmental factors that impact physiological state, such as diet, infection, and societal stress, can greatly impact stem cell function. Neural stem cells (NSCs) in the hippocampus divide to generate new neurons in the adult, and are known to be regulated by environmental factors. Diet-induced obesity is a modern epidemic, leading to hyperinsulinemia and diabetes. Obesity has been linked to poor performance in cognitive tests involving memory, and depression. Adult hippocampal neurogenesis is required for the proper formation of memories and learning, and has also been linked to depression. It has been suggested that a high-fat diet, and resulting obesity, impairs hippocampal neurogenesis. However, it remains unclear exactly how obesity affects adult NSCs. We will use inducible Cre recombinase genetic technologies, and advanced microscopy and image analysis, to elucidate the effects of obesity on hippocampal neurogenesis in a mouse model, with single NSC resolution. As obesity is known to alter insulin/insulin like growth factor(IGF) signalling in a variety of ways, we will elucidate the function of this pathway at the single NSC level with unsurpassable resolution in space and time, and investigate the interplay between obesity, insulin/IGF, and NSC dynamics. This project keeps a researcher with a history of research excellence in Europe, and facilitates their mobility to a distinct World-class research environment. The project utilises state-of-the-art techniques to generate new insights into the regulation of stem cells, with great potential health and economic benefits, thus helping to secure the excellence and competitiveness of Europe. Further, this project allows the researcher to gain the skills necessary to become an independent research leader.

Keywords: neural stem cell,self-renewal,hippocampus,insulin-like growth factor,insulin,obesity.
Modelling human ageing: developing and interrogating an integrated model of ageing to identify causal relationships between hormonal changes and gene expression changes (INTEGRAGEING)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-11-15
End date: 2014-11-14
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 1
Project status: CLOSED

Ageing has a profound impact on human society and modern medicine, yet it remains a major puzzle of biology. Both hormonal and gene expression changes have been implicated as causal mechanisms of ageing. It is not clear, however, which molecular or physiological changes are more important drivers of the process of ageing or how they influence each other. This project aims to develop and interrogate an integrated model of ageing to identify causal relationships between age-related changes at different biological levels. Specifically, this project aims to: 1) Build a mathematical model of age-related gene expression and hormonal changes with age; 2) Determine the causal relationship between these age-related changes using in silico analyses. 3) Develop a new model of ageing based on the results obtained to highlight the new causal relationships identified.

Keywords: ageing,systems biology,bioinformatics,hormonal changes,gene expression changes,mathematical model
Demonstration Of New Qualitative Innovative Concept of Hydrogen Out of windTurbine Electricity (DON QUICHOTE)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Collaborative project
Partnership: FCH (Art-185)
Countries involved: Belgium,Germany,European organisations area,Germany,Iceland,Italy,Netherlands,Belgium
Call:  (FCH-JU-2011-1, 2011)
Start date: 2012-10-01
End date: 2018-03-31
Duration (months): 66.0
Total project cost (EUR): 4936804.57
EU funding (EUR): 2954846.0
Participants: 9
Project status: CLOSED

The project “Don Quichote” aims at the long-term demonstration of the readiness of the technology of the combination of renewable electricity and hydrogen; facts-based data generated in this project is the base for analysis for further deployment and implementation of combined systems “renewable electricity – hydrogen”. Linked to the technical demonstration emphasis will be put on analysis of regulation, codes, standards, on LCA/LCI, on total cost of ownership and on implementation ways all over Europe.

Keywords: hydrogen,renewable,electricity
Fostering cross-cultural communication: Identifying the linguistic factors that promote comprehensibility in academic and workplace settings (L2 COMMUNICATION)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2012-04-01
End date: 2016-03-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Oral communication is a two-way process, involving a message sender and receiver. In telecommunications, a good technician can often efficiently repair a faulty signal. However, when it comes to human information exchange, and particularly when interlocutors are from different linguistic and cultural backgrounds, troubleshooting the unsuccessful transmission of a message is a more abstract and complex process. This is because myriad linguistic and non-linguistic factors interact to facilitate or hinder successful communication. My research, which seeks to elucidate different facets of this complex problem, is grounded in the goal of identifying the aspects of second language (L2) speech that are most important for achieving effective cross-cultural communication. A mixed-methods approach will be used to accomplish four major research goals: (1) "disentangle" the aspects of L2 speech that, while noticeable or distracting, have little bearing on listener understanding, as opposed to those that genuinely impede communication, (2) validate an L2 comprehensibility scale, originally developed in the Canadian context, for use on UK campuses, (3) examine the potential biasing effects of listeners’ social variables on their ratings of L2 pronunciation, and finally (4) investigate the effects of haphazard peer-pairing practices on test-takers’ performance on collaborative tasks, particularly with respect to phonological accommodations. Taken together, this research will address the pressing social-educational challenges of reducing language barriers and improving the oral communication skills of newcomers, in order to facilitate their social integration. With the support of the Marie Curie CIG, I will establish a state-of-the-art L2 speech laboratory. This facility, which is crucial for conducting high-caliber L2 pronunciation research, will put the University of Bristol on the map as a center of emerging research strength in this area both within Europe and internationally.

Keywords: assessment,comprehensibility,cross-cultural communication,individual differences,interaction,mixed methods research,pronunciation,rating scales,second language instruction,speech sciences
Material Testing and Recommendations for Hydrogen Components under fatigue (MATHRYCE)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Collaborative project
Partnership: FCH (Art-185)
Countries involved: France,Finland,European organisations area,United Kingdom,Italy,Italy
Call:  (FCH-JU-2011-1, 2011)
Start date: 2012-10-01
End date: 2015-09-30
Duration (months): 36.0
Total project cost (EUR): 2446372.6
EU funding (EUR): 1296249.0
Participants: 8
Project status: CLOSED

The deployment of a large hydrogen infrastructure with societal acceptance relies on the development of appropriate codes and standards to ensure safety. While hydrogen infrastructures are gradually being built all over the world, there exist no international standard to properly ensure fitness for service of pressure vessels subject to hydrogen enhanced fatigue. For example, high pressure compressors and pressure buffers in FCV refuelling stations experience cyclic loading due to pressure variation. The MATRHYCE project aims to develop and provide an easy to implement vessel design and service life assessment methodology based on lab-scale tests under hydrogen gas. This methodology will be based on selection and further development of the most appropriate, reliable and easy to handle lab-scale test under hydrogen pressure to quantify the hydrogen induced fatigue of a material. The results shall be transferable, allowing to design a component and to assess its lifetime without full scale tests. At least three types of lab-scale tests will be carried out and carefully analysed to address the fatigue of pressure vessel steels without and under hydrogen pressure. The proposed rationale will be finally validated by means of fatigue tests under hydrogen pressure on full scale components. The obtained results and conclusions will allow prioritized recommendations to support ongoing or new RCS initiatives at the international level. Indeed, this project will provide data and methodology necessary to improve European and International standards on high-pressure components exposed to hydrogen-enhanced fatigue. The project aims to support and speed up the build of a safe and harmonised Hydrogen supply network in Europe.

Keywords: hydrogen pressure vessel,hydrogen enhanced fatigue,metallic component testing,hydrogen embrittlement,recommandations,rationale for design and life assessment,prenormative development
Development of PEM Fuel Cell Stack Reference Test Procedures for Industry (STACKTEST)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Collaborative project
Partnership: FCH (Art-185)
Countries involved: Germany,France,Denmark,Germany,Poland,Denmark,Spain,Germany,European organisations area,France,Germany
Call:  (FCH-JU-2011-1, 2011)
Start date: 2012-09-01
End date: 2015-08-31
Duration (months): 36.0
Total project cost (EUR): 5637780.2
EU funding (EUR): 2909898.0
Participants: 11
Project status: CLOSED

In this project proposal, industry wide harmonized test procedures for PEFC stacks shall be developed and validated. The proposal builds on experiences gained in the FCTESTNET, FCSTEQA series of projects taking up the methodology developed there and expanding it to the test of PEFC stacks. Furthermore, experiences of individual consortium members have long time experience in international standardization. Performance / functional, durability and safety outputs for vehicle propulsion, stationary and portable applications shall be addressed. Generic test modules addressing the effects of outputs to the variation of a single test parameter shall be defined and experimentally validated on a stack level. From these building blocks, selected application oriented test programs shall be derived and validated as well. A two phase approach is pursued starting with an initial selection and definition phase followed by experimental validation. Subsequently, a review is carried out followed by a second validation phase. The consortium mainly consists of experienced research organizations, all working in close contact with and providing testing services to industry. The test modules and test programs are expected to be methodologically sound and independent. Contact to industrial practice will be established by the implementation of an industrial advisory group consisting of selected key stakeholders along the value chain of the fuel cell industry. The consortium will liaise with international standardization activities and contribute to the improvement of existing standards by pre-normative research and – if deemed necessary – initiate new work item proposals on performance and endurance testing of PEFC stacks.

Keywords: pefc stack test procedure
Integrated hydrogen power packs for portable and other autonomous applications (HYPER)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Collaborative project
Partnership: FCH (Art-185)
Countries involved: United Kingdom,France,United Kingdom,Germany,Poland,France,European organisations area
Call:  (FCH-JU-2011-1, 2011)
Start date: 2012-09-03
End date: 2015-09-02
Duration (months): 36.0
Total project cost (EUR): 3923909.8
EU funding (EUR): 2221798.0
Participants: 7
Project status: CLOSED

The proposed HYPER System is a scaleable and flexible portable power platform technology representing significant advances in terms of fuel cell development, hydrogen storage and associated supply. R&D will generate both new scientific knowledge and new technologies for exploitation. Specifically the project will: • Focus on developing a system based on application specific operational and performance targets, informed by early and ongoing end user intelligence; • Embed cost improvement and design for manufacture within the development pathway to optimise material and assembly costs and meet key cost targets; • Demonstrate complete application specific prototypes in the field with end users; • Deliver a market ready system that is flexible in design, and cost effective, for rapid roll out across multiple applications. The HYPER System can be readily customised to meet a range of application specific requirements including: power output, energy (or runtime), fuelling options, and cost (capex and opex). The system is based on a modular LT PEM fuel cell system with a common interface to use with alternative hydrogen supply modules. Two generic types of (interchangeable) hydrogen storage module will be developed: a bespoke gaseous hydrogen storage module; and a solid-state hydrogen storage module based on nanostructured hydrogen storage materials. Two proof of concept HYPER Systems will be developed and demonstrated; 100 We portable power pack/field battery charger, and a 500 We (continuous) range extender for a UAV. This will validate the scalability and robustness of the system whilst addressing early market opportunities that are aligned with the direct commercial interests of the Consortium Partners. The Consortium will provide a European supply chain, and early routes to market, for the subsequent commercial exploitation of the HYPER System.

Keywords: portable fuel cell hydrogen storage low temperature pem modular design for manufacture advance hydrides nanostructuring thermal conductivity solid state battery recharger unmanned aerial vehicle
HyLIFT-EUROPE - Large scale demonstration of fuel cell powered material handling vehicles (HYLIFT-EUROPE)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Collaborative project
Partnership: FCH (Art-185)
Countries involved: Germany,Germany,United Kingdom,Italy,European organisations area,United Kingdom,France,Denmark,France,Germany,Germany,Denmark
Call:  (FCH-JU-2011-1, 2011)
Start date: 2013-01-01
End date: 2018-12-31
Duration (months): 72.0
Total project cost (EUR): 15680960.2
EU funding (EUR): 6896871.0
Participants: 13
Project status: CLOSED

The aim of HyLIFT-EUROPE is to demonstrate more than 200 fuel cell material handling vehicles and associated refuelling infrastructure at 2 sites across Europe (the initial plan foresaw 5-20 sites), making it the largest European trial of hydrogen fuel cell material handling vehicles so far. This continues efforts of the previous FCH JU supported HyLIFT-DEMO project. In the HyLIFT-EUROPE project the partners demonstrate fuel cell systems in material handling vehicles from the partner STILL and from non-participating OEMs. STILL purchases fuel cell systems from suppliers according to the FCH JU purchasing rules (“principles of economy, efficiency and effectiveness”). Fuel cell vehicles from other non-participating OEMs are also demonstrated due to identified customer needs. The high volume combined with the FCH JU support is enabling a cost-neutral demonstration operation for vehicle-users. Dialogues have been established with 33 vehicle-users with a combined fleet of 2,097 vehicles of the types targeted for demonstration. At the vehicle-user sites 2 hydrogen refuelling stations (HRSs) are to be deployed (initially the deployment of 5-20 HRS was planned) using the latest technology by Air Liquide. To arrive at the target hydrogen price of 8-12 €/kg (average target < 10 €/kg) dispensed at the pump, vehicle deployment locations are to be chosen close to hydrogen production locations whenever possible in order to arrive at the lowest hydrogen supply cost. The project partners cover the entire value chain and all the disciplines and technologies required for providing fully working hydrogen powered fuel cell material handling solutions ranging from vehicle manufacturers, infrastructure operators to SME companies. The partners will also plan and ensure initiation of supported market deployment beyond 2018 and validation of performance targets on durability, efficiency and costs from the demonstration activities. Project results and experiences will be disseminated throughout Europe targeting early adopters of hydrogen vehicles, focused on large European industrial users of material handling vehicles, as well as on key policy and industry stakeholders.

Keywords: hydrogen refueling station,fuel cell systems,material handling,large scale demonstration,forklift,airport tow tractor
Development of Auxiliary Power Unit for Recreational yachts (PURE)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Collaborative project
Partnership: FCH (Art-185)
Countries involved: Netherlands,Denmark,Greece,European organisations area,Netherlands
Call:  (FCH-JU-2011-1, 2011)
Start date: 2013-01-01
End date: 2016-06-30
Duration (months): 42.0
Total project cost (EUR): 2884875.6
EU funding (EUR): 1641194.0
Participants: 5
Project status: CLOSED

IIn Europe there is a very narrow technology base in portable fuel cell systems which can be applicable for various areas like emergency and remote power, recreational applications, personal portable power and educational devices. The PURE project targets these markets with the primary focus on maritime applications with a device, which will be portable, low weight and volume, based on improved HT PEM fuel cell technology. This proposal describes the project in which a fuel cell system will be designed, build, tested and demonstrated with emphasis on meeting all major technical requirements the codes and standards required to be integrated in a maritime application. The objective of the PURE project is to create a system fueled by propane/LPG, which is converted into a hydrogen rich stream and subsequently fed into a HT PEM stack based on PBI technology. In the end the system delivers electric power to a cover the hotel power demand of a small yacht. The use of off-the-shelf, mass-produced components and design practices both developed in previous European funded projects will result in a small system which is low cost and able to reach the specifications. The consortium gathered to work in this project is a combination of partners who have experience in: 1. Defining the market requirements, codes and standards of the system 2. Translating these requirements into technical specifications and models 3. Designing and building prototype systems 4. Testing and validating the systems in laboratory environment and through real life demonstration in a yacht. This covers the value chain of the system under discussion. The final result will be two working prototypes of the PURE system, which will be demonstrated under laboratory environmental condition and in a real ship to show that it is robust enough to be ready for the next phase of field trials.

Keywords: auxiliary power unit,apu,fuel cells,recreational yachts,lpg,propane