Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Modeling first-order Mott transitions (FIRSTORM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Italy
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-09-01
End date: 2023-02-28
Duration (months): 78.0
Total project cost (EUR): 1422684.0
EU funding (EUR): 1422684.0
Participants: 1
Project status: CLOSED

Mott insulators are “unsuccessful metals”, where conduction is impeded by strong Coulomb repulsion. Their use in microelectronics started to be seriously considered in the 1990s, when first reports of field-effect switches appeared. These attempts were motivated by the expectation that the dielectric breakdown in Mott insulators could suddenly release all formerly localized carriers, a significant potential for nanometer scaling. Over the very last years striking experimental data on narrow-gap Mott insulators have finally materialized that expectation disclosing an unprecedented scenario where the metal phase actually stabilized was only metastable at equilibrium, which foreshadows exciting potential applications. These new data call for an urgent theoretical understanding so far missing. In fact, the conventional portrait of Mott insulators has overlooked that Mott transitions are mostly 1st order, implying an extended insulator-metal coexistence. As a result, bias or light may nucleate long-lived metastable metal droplets within the stable insulator, as indeed seen in experiments. The unexpected 1st order nature of dielectric breakdown in Mott insulators and its poorly explored but important conceptual and practical consequences are the scope of my theoretical project. I will model known Mott insulators identifying the variety of mechanisms (Coulomb, lattice distortions) that support and boost the 1st order character of the Mott transition. I will model and study insulator-metal coexistence and associated novel phenomena such as those related to nucleation and wetting at the interface, including possible unexplored role of quantum fluctuations. I will then simulate in model calculations the spatially inhomogeneous dynamics and non-equilibrium pathways across the 1st order Mott transition, relating the results to ongoing experiments in top groups. The outcome of this project is expected to yield immediate conceptual as well as later technological consequences.

Keywords: metal insulator mott transitions
Mosses as a gateway of nitrogen into northern ecosystems (MYCOMOSS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-03-01
End date: 2020-05-30
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

High latitude ecosystems, which experience particular high rates of climate warming are subject to changes in nitrogen (N) cycling due increased decomposition and changes in atmospheric N fixation and deposition. In cold ecosystems, temperature and low N availability restricts organic matter decomposition and plant growth, which affect ecosystem carbon (C) storage and thus climate feedback mechanisms. Understanding N cycling in high latitude ecosystems is therefore essential for understanding consequences of climate change. Mosses, which constitute a major component in high latitude ecosystems, intercept N entering the ecosystem via deposition and they host bacteria that fix atmospheric N. Therefore, they may be an important source for new N to the rest of the ecosystem. However, mosses do not easily decompose and the fate of N taken up by mosses is not well understood. Most vascular plants optimise their N uptake through partnerships with mycorrhizal fungi, which in return for labile C take up nutrients via extensive mycelium in the soil, and transfer a share to the host. Despite the presence of mycorrhizal fungi in the moss layer, their role in transfer of N from moss to plants is unknown. The overall aim of MYCOMOSS is to develop mechanistic and quantitative understanding of the role of mosses as providers of new N to N-limited high latitude ecosystems under climate change. This will be achieved by 1) making a full N budget of mosses under the effect of climate change manipulations in the field, 2) by exploring the role of different types of mycorrhiza across three major high latitude ecosystem types of Europe 3) and by tracing N from mosses through the ecosystem using stable isotope labelling. The quality of the implementation will be ensured by the fellow’s expertise in moss ecology and plant interactions, the host’s specialized knowledge about element cycling, and the secondment partner’s expertise on fungal community ecology.

Keywords: mosses,bryophytes,mycorrhizal fungi,nitrogen,climate change impacts,subarctic forest,boreal forest,tundra,element cycling,n fixation,c storage,climate feedback,stable isotopes
The Human Imprint: Western and Chinese Anthropocene Fictions (The Human Imprint)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-08-06
End date: 2020-08-05
Duration (months): 24.0
Total project cost (EUR): 166156.8
EU funding (EUR): 166156.8
Participants: 1
Project status: CLOSED

This action addresses a new chapter in ecocriticism: the advent of the ‘Anthropocene’ in contemporary literature. In recent years, the profound changes in our relationship with the biosphere influence not only our lives as consumers, but also the plots of the stories we read. As modern societies are starting to feel the first effects of climate change, rapidly increasing levels of carbon dioxide emissions and the fouling of waterways, novels have become a key medium in the discussion of the real, anticipated and imaginary implications of our life in the ‘Anthropocene’. As a reflection on socio-political and ecological realities of our lives, literature projects various ways how life in this new reality can be imagined, e.g. as the break-down of social norms or as the wake-up call to a post-human future. Adam Traxler’s notion of ‘Anthropocene fictions’ will be extended to include Chinese-language texts. Just like the industrialised countries of Europe and North America, the Greater China Region is struggling to come to terms with its experience of climate change and resource depletion, and, at the same time, a growing sense of environmental guilt. Despite striking similarities in how these texts dramatize dystopian landscapes, cultural heritage does play a role in how the future of humanity is imagined. Surprisingly, these differences are not necessarily related to conventional concepts of China and ‘the West’. On the most general level, this action will allow researchers and the wider public to understand how the environmental crisis is experienced in different regions around the globe.

Keywords: comparative literature,chinese studies,sinology,germanistik,german studies,comparative criticism
Cosmological Visionaries: Shamans, Scientists, and Climate Change at the Ethnic Borderlands of China and Russia (COSMOVIS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: United Kingdom,United Kingdom
Call: ERC Synergy Grant (ERC-2019-SyG, 2019)
Start date: 2020-09-01
End date: 2026-08-31
Duration (months): 72.0
Total project cost (EUR): 6458201.0
EU funding (EUR): 6458201.0
Participants: 2
Project status: SIGNED

Cosmological Visionaries explores what global environmental initiatives of the future will look like, by asking: (1) How can scientists, shamans, priests, and other indigenous holders of animistic knowledge collaborate in regions of climatic vulnerability and (2) What are the geopolitics of climate change and the policies that surround it? Starting from the position that cosmology often evokes religious ways of knowing or being, the project brings together anthropologists, ethnologists, historians and philosophers of science and ethics, religious studies experts, space and satellite researchers, indigenous leaders and environmental scientists to examine how climate change is managed at the ethnic borderlands of China and Russia. The widespread deforestation undertaken in Siberia to meet Chinese market demands for wood is melting Russia’s vast permafrost, accelerating the release of ancient greenhouse gases, which carbon capture and storage technologies of the future will not manage. Our project is an academic and a practical intervention driven by two research teams – the China Team and the Russia Team – with a fourfold methodology. Firstly, we will uncover the scientific and indigenous views on climate change in Southwest China and Siberia. Secondly, we will mobilise dialogues between scientists and animistic peoples to mutually inform their approaches to climate change. Thirdly, we will explore how collaboration can benefit both parties. Fourthly, we will map the policies and geopolitics of climate change in China and Russia. Scientists who collaborate with indigenous peoples can get more subtle data than when working alone. Indigenous persons who supply scientists with advice and logistical help can source scientific initiatives for managing local climate change. This feedback loop between scientists and indigenous peoples, advocating for each other, can enable religious leaders and scientists to translate shared findings into visions that everyone can commit to.

Keywords: social anthropology,shamanism,animism,deforestation,ethnic minorities,china,russia,history and philosophy of science,philosophy of ethics
New Digital Pigment Printing System for every Surface, for every Industry, faster, with less energy requirements and with no water needs (Green Drop)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Digital printing in an inkjet-based method has open many application areas including wide format graphics and various industrial applications such as textiles. While the digital textile printing market is growing at an annual output rate of 20%, the proportion of digital textile printing users only reached 2%. This is mainly due to the current limitations of the method. In order to print different types of textiles, varied types of inks are required since each ink is suitable for a specific fabric. Thus, the printer will adjust to the need for pre and post treatment printing process as well as printing quality ensuring ink stability on the fabric. This reflects on high production costs, lengthy process treatment and usage of several inks. Creazioni Digitali, present in the fabric printing sector since 2006 realise that we could create a state of the art system for textile digital printing using specialised inks and short pre and post treatment processes. GREENDROP is our project to launch the pioneer Digital Printing machinery system that will revolutionized the digital printing market for the Fashion, Automotive, Advertising and Home design segment sectors. GREENDROP system improves the working environment as it enables a 40% reduction on time and energy pre and post treatment, 30% reduction on ink usage and 0% water consumption in the printing process. In addition, the system can maintain the colour above the surface of the fabric, complying with the ISO standards on colour fastness. Our target market is promising: the global Digital Printing Market is forecast to reach €25 Billion by 2023 at a CAGR of 4.48% between 2017 to 2023 with the ink market segment holding the largest share. We expect at least to capture a Serviceable Obtainable Market of 200 textile and clothing companies, €7.5M market value with a ROI of 1.62 by 2026.

Keywords: textile printing,digital printing,innovation for textile printing
DNA Data storage (DNA DS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Slovenia
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

According to Domo Inc., we were producing 2.5 quintillion bytes of data every day in 2017, and by 2020, it is estimated that for every person on earth, 1.7 MB of data will be created every second. This vast amount of data is stored on hard drives, flash drives and, for long-term archival storage, on magnetic tape. Even magnetic tape, the most durable of storage media, can preserve data no more than 30 years. What is more, the data archived on magnetic tape requires controlled climate (humidity and temperature), electrical energy, and a lot of physical space (huge data centres) to preserve the data, not to mention the necessary non-sustainable raw materials to produce the tape. BioSistemika has developed an innovative, high-tech solution to address these problems by storing digital data into the DNA molecule – the oldest, most efficient data storage medium in history. As a storage medium, DNA is incomparably more efficient than any of humanity’s artificial data storage media in nearly all aspects, capable of storing more than 450 petabytes (450 x 103 terabytes) in a single gram of substance, compared to 0,15 terabytes in a gram of the state-of-the-art LTO-8 magnetic tape by IBM (3 million-fold difference). This means that whole data centres could both be scaled down to the content of a single vial of liquid and be duplicated in a matter of hours with minimal to no costs. Furthermore, DNA was optimized to remain durable and intact within extremely variable environments by the forces of nature. It does not require electricity to preserve data and is resistant to most electromagnetic radiation and most other forms of degradation (e.g. temperature), thus making it the perfect medium to store and archive data. Our business model canvas, which sums up our project, is attached with this application.

Keywords: biological knowledge,it expertise,software development for laboratories,biotechnology,molecular biology,computer and information science,specifications,coding,testing and maintenance
Faron leading the way in macrophage guided immunotherapy (MAGIF)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Finland
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2020-10-01
End date: 2022-09-30
Duration (months): 24.0
Total project cost (EUR): 4544008.5
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Cancer is a leading cause of death in the world despite relentless research to discover new treatments. There were over 18M new cancer cases and 9.6M deaths due to cancer worldwide in 2018. Human suffering due to cancer is devastating. The impact and cost of cancer to society is extensive and complex. Faron aims to provide a new solution that could replace several currently used ineffective cancer treatments. Faron is a Finnish biotech company committed to high-quality R&D to fulfil the company’s mission of saving lives. Faron’s game-changing immuno-oncology (IO) treatment CLEVEGEN revolves around a key immunosuppressive molecule named Clever-1 on tumour associated macrophages, responsible for cancer growth and spread. CLEVEGEN is an anti-Clever-1 antibody that brakes the immunosuppressive tolerance of tumours and activates the patient’s immune defences against cancer. The first results from Faron’s first-in-human clinical trial with CLEVEGEN are very positive with early clinical benefits with a switch in patients’ immune profile towards immune stimulation leading to tumour shrinkage in cancer types where nothing has worked before. The early evidence of a clinical response to CLEVEGEN strengthens Faron’s value proposition of it as a break-through cancer treatment. CLEVEGEN has major advantages compared to other IO treatments. Most importantly, patients who would benefit from the treatment can be screened. This would prevent futile treatment and deliver savings in healthcare resources and cost. The CLEVEGEN program is focused on deadly cancer types without effective treatment options and over 3.5M new cases and 2.3M deaths yearly. The market opportunity is clear. With transition to other cancers and the possibility of becoming the first line of therapy due to an exceptional safety profile, the potential up-scale of CLEVEGEN is enormous. There is nothing like CLEVEGEN on the market. CLEVEGEN could secure Faron a world-leading position in the new wave of macrophage guided immunotherapy.

Keywords: cancer,treatment,macrophage,anti clever 1,pharmaceuticals,immunotherapy,immuno oncology,checkpoint inhibitor
Neurovascular interplay in the hematopoietic stem cell niches in homeostasis and myeloproliferative neoplasias (NVHSC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-04-01
End date: 2018-03-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Research of the bone marrow (BM) hematopoietic stem cell (HSC) niche has long been the study of mesenchymal cell populations. Only recently, distinct vascular niches have been identified to balance HSC activation and quiescence. Whereas arterioles together with sympathetic nerves and NG2+Nesbright cells form a niche for quiescent HSC, actively proliferating HSC are closely located to sinusoidal vessels and LepR+Neslow cells. However, it is still elusive how different blood vessels interact with different niche cells in distinct vascular niches during BM homeostasis and leukemic progression. Therefore, the present proposal aims at studying the role of distinct vascular BM niches in controlling HSC maintenance and malignant progression by means of genetic mouse models, FACS analysis, high resolution whole mount BM imaging and RNA sequencing. Besides investigating the direct influence of EC on HSC in different vascular niches, the interaction of EC with perivascular MSC and particularly neurons will be compared between the sinusoidal and arteriolar niche under steady-state and malignant conditions. Changes of the vasculature and downstream effects on HSC and other niche cells will be analyzed during therapeutic targeting of leukemia and the vascular compartment will be evaluated as novel target for niche-targeting leukemia combination therapies.

Keywords: hematopoietic stem cell,vascular niche,blood vessels,bone marrow,neurovascular link,sympathetic nerves,leukemia,chemotherapy,anti angiogenic therapy
EK200 - Airborne Wind Energy and Storage system, catering to Off-grid and Mobile End-uses (AWESOME) (EK200-AWESOME)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Germany
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-08-01
End date: 2017-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The aim of the EK200-AWESOME project is to bring the EK200 to market - an integrated 100 kW container based airborne wind energy (AWE) converter and storage solution catering to off-grid applications and mobile end-uses. The EK200 can be deployed stand-alone or in arrays. The EK200 could also shape the future for AWE and provide basis and principles for up-scaled MW units Motivation The EK200 will add to renewables’ part of the energy-mix and support off-grid micro-grids providing distributed and diverse power sources for geographically remote communities or industrial activities Solution The physical height of conventional wind turbines is limited by the enormous stresses on the structure and by mechanical resonance phenomena. The EK200 will replace the most effective part of a conventional wind turbine, the tip of the rotor blade, by a tethered kite - operating economically even at low-wind onshore locations. USPs: * Low Cost of Secure Energy: Ultra high capacity factors, yielding > 5,000 full load hours pa * Portability and minimal interference: Less than 5% of the material resources used in a conventional wind mill with the same yield * Uninterrupted Power Supply: Tapping into stable and abundant high altitude winds * Ease of Maintenance: Least amount of moving airborne parts in the industry * Flexibility in Operation: Portable units. Smart control technology Project Outputs Commercialization of the EK200 is a high risk/high reward action. As a result we are conducting a Feasibility Study, resulting in a complete Business Plan, taking a into account end-user needs, market analysis, cost assessment, IP validation, pilot design and risk assessment - all feeding into our go-to-market strategy Opportunity High power reliability level and the need for an effective demand-response load management present a conducive ecosystem for off-grid to flourish. We seek to capture a share in this attractive market valued at EURbn 2.8 in 2014, growing to EURbn 6.3 in 2019

Keywords: airborne wind energy,off grid,micro grid