Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Airport-Level DemonstRatIon of Ground refuelling of Liquid Hydrogen for AviaTion (ALRIGH2T)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Clean and competitive solutions for all transport modes
Action type: Innovation actions
Countries involved: Italy,Austria,Germany,France,Norway,Spain,Switzerland,Israel
Call: Hydrogen-powered aviation (HORIZON-CL5-2023-D5-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 12920388.0
EU funding (EUR): 9999720.01
Participants: 21
Project status: SIGNED

ALRIGH2T responds in full to the “expected outcomes” and “scope” of the HORIZON-CL5-2023-D5-01-07 topic, by developing and demonstrating two alternative technologies for LH2 aircraft refuelling: - Direct LH2 refuelling, encompassing the definition of operational protocols for safe and rapid refuelling, the development and testing of a LH2 transfer pump and an instrumented tank, their integration in an iron bird laboratory for the execution of refuelling/defueling tests and the delivering of a digital twin model. - LH2 tanks swap refuelling, encompassing end-to-end logistic and supply chain of tank modules, the design of the associated on- and off-site infrastructure and its demonstration. Both concepts will achieve TRL 6 by the end of the project, undergoing a comprehensive technology evaluation informed by demonstration results in two major airports, i.e. Milan Malpensa and Paris (Orly or LeBourget) respectively. The two technology lines are complemented by transversal activities for the definition of technical and techno-economic boundary conditions, the demonstration of the use of H2 for ground operations (i.e. H2 powered tow vehicle, demonstrated at the Malpensa site) as well as environmental, safety and regulatory cross-cutting aspects. ALRIGH2T has the ambition of demonstrating, for the first time, LH2 refuelling in a scale compatible with airport operations, synergizing with the Clean Aviation research and development efforts at the aircraft level. The project is implemented by a consortium built on the competences of top European industrial players, positioned along entire hydrogen and aeronautic value chain, complemented by research and technology organisations and selected member of the Advisory Board, including the EASA. ALRIGH2T is expected to be a cornerstone in the path towards the deployment of LH2 as an aviation fuel, strengthening the European research and industry leadership and consolidating the role of green airports as hubs of the H2 economy

Keywords: airports,infrastructure,lh2 supply,lh2 demand models,lh2 tank,direct refuelling,tank swap,lh2 refuelling demonstration,hydrogen safety
Effects of extreme flow changes on periphyton biofilm and carbon cycling in Alpine streams (PeriCarb-EFA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,Italy
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-05-01
End date: 2025-11-30
Duration (months): 31.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 2
Project status: SIGNED

The year 2022 was a year of catastrophic extreme climatic events at an unprecedented scale. Rivers around the globe drying up, China's extreme heat wave, extreme floods in Pakistan and in the United States, are clear examples of a climate change scenario that is expected to be more and more pervasive in the next years. Despite evidence of the increase in frequency and intensity of extreme events, the effects of the extreme oscillations between droughts and floods on streams carbon cycling are still uncertain. Alpine streams are important contributors of inland water carbon and changes that occur in alpine streams can profoundly alter downstream reaches affecting the global carbon budget and in turn exacerbate climate impact in the future. PeriCarb, EFA aims at understanding how periphyton biofilms community composition changes due to extreme flow change events and the reduction in the recovery time for the microbial community between events. It will link biofilm changes in community composition to changes in carbon cycling and in greenhouse emissions. By linking microbial ecology and carbon biogeochemistry changes in alpine streams PeriCarb will inform on the impact of climate change on global carbon budgets. PeriCarb will constitute a multidisciplinary project joining the applicant's previous experience with the excellence of the host institution and a group of established collaborators. It will provide advances for the field of carbon biogeochemistry and allow the applicant to return to Europe to establish as a researcher.

Keywords: carbon cycling,ghg emissions,streams metabolism,organic matter,limnology
Heterozygous expression of insulin in Nannochloropsis (HERO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Ireland,United States
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2030-02-28
Duration (months): 42.0
Total project cost (EUR): 517435.92
EU funding (EUR): 517435.92
Participants: 3
Project status: SIGNED

As of 2024, more than 90% of the global insulin supply is controlled by just three conglomerates. Patents and license agreements restrict the use of optimised expression vehicles such as E. coli, S. cerevisiae, or P. pastoris, by the small/medium scale enterprises (SMEs) who can decentralise insulin production and cater to local demands. Project HERO (HEterozygous expRession of insulin in NannOchloropsis) aims to develop a novel microalgal platform technology for sustainable and accessible transgenic insulin production using Nannochloropsis oceanica as the model organism. The project builds upon the applicant’s recent discovery that N. oceanica (an ω-3 lipid rich, phototrophic microalgae) secretes the protease serine decarboxylase (SDC) during nitrogen scarcity. In this project, the transcriptome and secretome of N. oceanica under varying nitrogen concentrations will be comprehensively profiled after which, state-of-the-art plasmid designing techniques and CRISPR transformation pipelines will be used to insert the genes for insulin in the microalgal genome and express it as a fusion-protein with SDC. Controlled auto-proteolysis of the fusion-protein will greatly simplify and decrease steps in downstream insulin processing, thereby reducing overall water consumption and production costs. Moreover under nitrogen starvation, N. oceanica naturally over-produces high-value ω-3 lipids through biochemical pathways independent to SDC secretion. This offers the biorefinery benefits of multi-stream production (insulin and lipids) to further offset production costs. Finally, the engineered N. oceanica strain will be cultivated at pilot scale (100 L) to assess insulin yields, perform lifecycle analysis and establish its commercialisation potential. By empowering local SMEs to economically and sustainably produce insulin and supply them to their local communities, Project HERO intends to help democratise access to this life-saving drug to people across all financial tiers.

Keywords: microalgal,insulin,crispr,nannochloropsis
Spatialising Career Interventions for Inclusivity and Sustainability (SpaCIIS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark,Australia
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-08-01
End date: 2026-11-30
Duration (months): 28.0
Total project cost (EUR): 269236.8
EU funding (EUR): 269236.8
Participants: 3
Project status: SIGNED

The 'Spatialising Career Interventions for Inclusivity and Sustainability' (SpaCIIS) project aims to address rural sustainability through the unusual perspective of career education and guidance (CEG) provision. Existing research shows that rural CEG provision can encourage young people to leave their rural communities and the project aims to ask whether CEG provision can be reimagined to more fully meet the needs of rural young people and their communities. The project takes an interdisciplinary approach applying insights into place-conscious practice, and place and social justice, developed in the field of rural education to rural CEG provision. Utilising Research Circles (RCs) (a form of participatory research), the project engages three rural Danish communities in researching the needs of their communities and co-designing place-conscious CEG interventions. The project contributes to scholarship in CEG by: developing a new conceptualisation of social justice for CEG including consideration of spatial aspects of inequality, and developing a new model(s) of place-conscious CEG provision. The project also extends rural development scholarship by exploring the role specifically of CEG provision in economic and population sustainability of rural communities. Contributing to rural education scholarship, the project highlights the role of CEG provision within community-education linkages and explores the value of RCs as an innovative way to bring together different perspectives and generate community led innovations in this provision. Practical outputs include the development of tools for delivering place-conscious career education that can be adapted for use across different rural communities, CEG services and CEG practitioners. Through these outputs the project seeks to improve the quality and efficiency of rural CEG services.

Keywords: career guidance,career education,youth transition
The role of social cognition for mental health (DevSocMH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: SIGNED

Mental health problems affect approximately 12% of children and have dramatic consequences at the individual and societal level. This mental health crisis is rapidly worsening as a consequence of the pandemic. Understanding mechanisms contributing to mental health outcomes is critical to identify children at risk of unfavorable mental health outcomes and to devise targeted and effective interventions. Since precursors of mental health problems manifest in childhood as altered social behavior, my research project aims to uncover developmental pathways to altered socio-emotional behavior in preschool children. First, I aim to identify cognitive processes underlying socio-emotional behavior that can be directly targeted in interventions. To this end, I propose to study the relationship between social cognition and socioemotional behavior in preschool children. Even though the relationship has been established in older children and adolescents, we lack research focusing on infancy and early childhood. Evidence of this relationship earlier in life promises to have important implications for clinical interventions. Second, I aim to help identify a neural marker of altered behavior that can be leveraged for early detection of at-risk individuals. To this end, I propose to use neuroimaging (functional magnetic resonance imaging or fMRI) to measure the brain network underlying social cognition and examine its association with socioemotional behavior. A critical novel aspect of my work is that I will validate the use of a portable neuroimaging technique (functional near infrared spectroscopy or fNIRS), which can be more easily deployed in clinical practice for early detection strategies.

Keywords: fnirs,mri,fmri,socio emotional development,social cognition,preschool children,mental health
Critical Geopolitics of Nuclear Fuel Supply in Europe (GeoNuFE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1346830.0
EU funding (EUR): 1346830.0
Participants: 1
Project status: SIGNED

How do countries build their nuclear fuels supply policies? The ongoing political renaissance of nuclear power through the world raises concerns about European Union states’ ability to fill their needs. Despite efforts to build a common strategy, EU members follow diverging paths to secure their supplies. However, energy security studies are so far unable to explain this heterogeneity, creating miscomprehensions between countries and ill-informing energy policies. First, we lack any empirically informed works on the geopolitics of nuclear power. Second, all theoretical frameworks studying supply security were built over hydrocarbons. But if we want to decarbonize our societies, we will first have to decolonize these tools from the grip of fossil fuels. Third, while critical security studies have called for more space-sensitive approaches, engagement with political geography theories remains limited. GeoNuFE aims at filling these gaps by questioning the variables behind the spatial heterogeneity of nuclear fuel supply strategies. To do so, I develop an innovative analytical framework bridging “critical security studies” and “critical geopolitics” through their ongoing turn to new materialist approach and assemblage. GeoNuFE will compare four countries: France, Finland, the UK, and Hungary, following three steps. [1] I’ll confront the current fossil-fuel informed theories to actors of the nuclear sector to build the first ever analytical framework of “objective supply security” adapted to it, and apply it to the four countries. [2] I’ll identify the influence of EU membership by digging into how the Euratom Supply Agency, who is responsible for allowing supply contracts to member states, produces and performs “security”. [3] I will trace and compare the geopolitical assemblage which explains the supply strategies in each country. Expected results will provide essential knowledge of the geopolitical dimensions of energy transitions to better inform EU energy policies.

Keywords: geopolitics nuclear energy
Providing research infrastructure services to support Next Generation EU (Infra4NextGen)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Services and infrastructures
Action type: Research and Innovation actions
Countries involved: United Kingdom,Slovenia,Germany,Norway,Bulgaria,Hungary,Austria,Czechia,Portugal,Belgium,Iceland,Finland,Sweden,France,Netherlands,Italy,Poland
Call: Research infrastructure services to enable R&I addressing main challenges and EU priorities (HORIZON-INFRA-2023-SERV-01, 2023)
Start date: 2024-03-01
End date: 2028-02-29
Duration (months): 48.0
Total project cost (EUR): 9751830.0
EU funding (EUR): 9751830.0
Participants: 35
Project status: SIGNED

This four-year project will harness outputs from key social science RIs in Europe and other reliable sources to support the aims of the ‘Next Generation EU’ programme and to inform EU youth policy. Virtual access will be provided to the outputs through special installations (portals) developed during the project. The core of the proposal is a set of existing research ‘services’, which will be re-purposed and customised to focus directly on the five themes: Make it Green; Make it Digital; Make it Healthy; Make it Strong; and Make it Equal. For each area, the consortium will work collaboratively to produce seven sets of resources: i) A searchable inventory of relevant variables drawn from multiple cross-national datasets; ii) Analytical summaries, suitable for policy makers and analysts new to the field, as well as interactive resources available through the project portal; iii) Harmonised and merged extracts from these datasets that reduce the burden on analysts and increase sample sizes; iv) New data collected through the ESS’s established CRONOS web panel infrastructure. Eleven countries will field five waves of the panel, each one dedicated to a NextGenEU theme. Free and rapid access to the data will be available through the CRONOS portal alongside analytical summaries; v) In-person and virtual deliberative forums with young people (aged 18-34) in four countries covering the five Next Generation EU’ themes; vi) An educational tool (E-NextGen) channelling our data for use in classrooms and by the general public; vii) Comprehensive training materials related to all project outputs.

Keywords: next generation eu,eu youth policy,social sciences,cross national,data,deliberation
Waste4Bio: Advancing Food Waste Utilization Through Multiplatform Biorefinery (Waste4Bio)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-03-01
End date: 2027-02-28
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 3
Project status: SIGNED

Food waste (FW) is a significant global issue, with around one-third of all food produced wasted annually. FW biorefineries constitutes a green route to valorise the enormous untapped potential of FW via its bioconversion into marketable products and fuels in a circular bioeconomy scheme. However, to date, FW biorefineries have not reached the maturity level needed for full-scale and widespread application. To meet the European Green Deal and Sustainable Development Goals, Waste4Bio project aims at engineering and validating an innovative, cost-competitive FW biorefinery for the cascade production of biohydrogen (bioH2) and biodegradable biopolymers (polyhydroxyalkanoates; PHAs). To this end, Waste4Bio will go beyond of the state-of-the-art of dark fermentation to design advanced mass transfer hydrogen-producing fermenters able to support a high density of biocatalyst and a superior bioH2 production performance. Waste4Bio will also upgrade the acidogenic gas mixture evolved by using well-engineered outdoor algal-bacterial photobioreactors to produce near-pure bioH2 and treat the carbon dioxide into algal biomass, contributing to a net-zero carbon balance for FW valorisation. In addition, the DF broth rich in short-chain carboxylic compounds will be further valorised for highly efficient PHA production with purple phototrophic bacteria (PPB). This action also aims at bringing deeper understanding of the microbiome, and its associated potential functionality and ecological interactions, involved in every fermentative bioH2 production, photosynthetic bioH2 upgrading, and PPB-based PHA production stage. Waste4Bio with transferable skills and a cross-sectoral nature will apply a cross-disciplinary approach involving bioprocess and chemical engineering, environmental biotechnology and microbiology and bioinformatics. A techno-economic model and a market-uptake roadmap will also be created to facilitate the fully exploitation of Waste4Bio.

Keywords: dark fermentation,biohydrogen upgrading,biopolymers production
OneBreath: High-performance Mechanical Ventilation for Low-resource Settings (Medical Device)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United States
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 3072714.0
EU funding (EUR): 3072714.0
Participants: 1
Project status: CLOSED

OneBreath is an early-stage medical device company that has developed a fundamentally simpler platform to provide mechanical ventilation. By discarding existing paradigms, OneBreath has dramatically lowered the cost of ventilation while maintaining a high level of accuracy. Our first product is designed to penetrate the vastly underserved markets in low- and middle-income countries (LMICs). The global spread of COVID-19 has highlighted the need for appropriate pandemic resources, especially sophisticated ICU equipment like ventilators. Recent second- and third-wave outbreaks further underscore the need for appropriate pandemic preparedness. Unfortunately, ventilators capable of treating critically ill patients such as these are expensive and ill-equipped for use in a mass casualty event or stockpiling, where electricity and high-flow oxygen may not be accessible, portability and durability are critical, and skilled users may be in short supply. The need is more critical in LMICs where funding and infrastructure to support critically ill patients are severely limited. To provide mechanical ventilation to large numbers of patients in scenarios like COVID-19, what is needed is a safe, inexpensive, and easy-to-use ventilator that is capable of rapid production and global deployment. OneBreath was founded at Stanford University to commercialize unique ventilation technology developed at Stanford Biodesign. The company is based in Palo Alto, CA, US, and Bangalore, India. OneBreath is backed by international venture funds and foundations and is currently working towards FDA approval (510k/EUA as a continuous-use ventilator) with assistance from the US Government’s Development Finance Corporation. Manufacturing is with Flextronics in Singapore.

Keywords: medical device,ventilator,low and middle income