Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Waste to Worth: A green solution for waste concrete powder and incinerator bottom ash reinforced by CO2 capturing in concrete (W2WGCO2)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Norway,Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-05-01
End date: 2025-10-31
Duration (months): 30.0
Total project cost (EUR): 210911.04
EU funding (EUR): 210911.04
Participants: 2
Project status: SIGNED

The world's population is growing continuously-and the waste generation is too. In 2019, 1052 M tonnes of the total EU waste generated was landfilled, 30% of which was from the construction sector, in particular waste concrete, and municipal incinerator bottom ash (IBA). Proper management of these wastes is one of the most important responsibilities to provide a healthy environment for future generations. Moreover, reducing CO2 emission to at least 55% below 1990 levels by 2030 is a must to reach a carbon-free society aligned with the European Green Deal. Hence, the proposed project aims to utilize waste concrete powder (WCP) and IBA as alternative materials to cement, and thereby convert these solid wastes into worth. This also helps to satisfy the cement demand in the construction industry as a massive CO2 emitter. The main objectives of W2WGCO2 are, to treat the WCP and IBA by CO2 capturing from emitted flue gas of cement plant, to manufacture the cementitious composite (CC) from carbonated WCP and carbonated IBA, and to study the performance of the CC in the green concrete application. This proposal involves extensive training of the researcher on the carbonation treatment method and green concrete technology in the host (NTNU) and advanced characterization of the carbonated wastes in the academic secondment (IETcc-CSIC). Life cycle assessment of carbonated solid wastes and green concrete products will also be studied to highlight the environmental impacts of the proposed project. In addition to the environmental benefits, the success of the project will boost both research and complementary skills of the researcher, including learning new experimental and analysis methods, communication, teaching and supervision skills, writing EU patent and ERC funding. Also, the expected results will be published in high-impact journals which improve the profile of the researcher and makes her a competitive person in the field of "sustainable and green building materials".

Keywords: green cementitious composite green concrete mineral carbonation,co2 capturing,waste concrete powder,incinerator bottom ash,dry aqueous carbonation,flue gas,cement based products
Exploiting single cell long non-coding RNA biology to target therapy-induced senescence in lung cancer (NONCO-MICROTIS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-05-01
End date: 2024-04-30
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: CLOSED

NONCO-MICROTIS will combine new findings in long non-coding RNA (lncRNA) biology with cutting edge research to uncover innovative therapeutic opportunities for the treatment of lung cancer, one of the most prevalent and deadliest types of cancer worldwide. Current treatments which are often insufficient, include the use of chemotherapy and radiation that induces tumor cell arrest. This process termed as therapy-induced senescence (TIS) has been considered a positive outcome for cancer therapy. However, there is evidence that TIS can be reversible leading to an aggressive phenotype and disease relapse. The low percentage of senescent cells in the tumor together with the lack of specific markers senescence senescence has prevented the development of methods to identify and target this population of cells. I will exploit the highly specific expression patterns of lncRNAs by tailored single cell methods to identify therapy-induced senescent cells and their relationship with the tumor microenvironment. Further, NONCO-MICROTIS will investigate the senescence-related roles of small peptides produced by TIS-lncRNAs to be exploited for the targeting of these singular cells within lung tumors. Altogether my study will define a new senescence signature using specific lncRNAs that will help to identify senescent cells and will provide information on how these cells impact the neighbouring populations. Moreover, it will uncover mechanistic roles of micropeptides in the regulation and targeting of senescent cells and will provide the basis for the use of micropeptides as therapeutic targets. NONCO-MICROTIS will combine cutting-edge techniques in transcriptomics and molecular and cellular biology techniques resulting in an original, multidisciplinary project with high potential for ground-breaking findings. Furthermore, it will allow me to reach the level of professional maturity needed to become an independent researcher.

Keywords: long non coding rna,micropeptides,therapy induced senescence,lung cancer,senescence associated secretory phenotype,single cell rnaseq spatial transcriptomics
Sea Environmental Awareness and Guard enhanced with Unmanned AI Robotic Detection (SEAGUARD)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Border Management
Action type: Innovation actions
Countries involved: Portugal,France,Greece,Ireland,Romania,Norway,Spain,United Kingdom
Call: Capabilities for border surveillance and situational awareness (HORIZON-CL3-2023-BM-01, 2023)
Start date: 2024-10-01
End date: 2027-03-31
Duration (months): 30.0
Total project cost (EUR): 5554791.28
EU funding (EUR): 4463268.27
Participants: 15
Project status: SIGNED

Illegal activities across external borders (land and maritime) are a threat to the security of the European Union. Better border surveillance capabilities are required to deter and monitor irregular border crossings. These should be interoperable across member states, ranging from the Mediterranean to the Nordic Countries, which have different border surveillance challenges. These should also be scalable, flexible and relocatable, since the needs along borders shift rapidly in time, with changing and improving threats. SEAGUARD project aims to address these needs. Situational awareness technologies will play a crucial role in the future of maritime border security by providing real-time information about the maritime environment, including vessel movements, cargo, and potential threats. The SEAGUARD project aims at developing an innovative and integrated approach to maritime cross-border surveillance that will enhance border security and management in Europe. The scope of this project includes the design, development, testing, and deployment of a cross-border surveillance system that will incorporate multiple sensing technologies integrated in both fixed and mobile platforms. This project will combine unmanned vehicles (Unmanned Aerial, Surface and Underwater Vehicles - UxVs), fixed buoys, (SMART) submarine cables, with advanced analytics and decision support. The system will be able to monitor and detect various types of threats, including illegal border crossings, smuggling of contraband, illegal fisheries and terrorist activities. The project will leverage new technologies and data analytics, enhanced by multi-domain autonomous cooperative platforms and multimodal communications, to provide real-time information and situational awareness to multiple border guards and other authorities, enabling them to detect and respond to potential threats coming from the air, surface or underwater, more effectively.
Charting Cell Type-Specific Nucleic Acid Immunity (SENTINEL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and I mmunotherapy
Panel description: The immune system , related disorders  and their mechanisms , biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases , innovative imm unological tools and approaches , including  therapies
Countries involved: France
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-10-01
End date: 2028-09-30
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Metabolic and immune pathways form an intricate network that maintains homeostasis. We recently unveiled that the Stimulator of Interferon Genes (STING), central to triggering cytosolic dsDNA-dependent type I Interferon (IFN) responses, inhibits the desaturation of essential dietary polyunsaturated fatty acids (PUFAs). STING thereby controls the generation of long-chain PUFAs (LC-PUFAs) that in turn inhibit STING activation. This double negative regulatory feedback loop operates as a key rheostat of homeostasis. Interestingly, we found that metabolic tissues, such adipose tissues, express low levels of STING, and that in vitro adipocyte differentiation leads to STING downregulation, although they retain their ability to produce type I IFNs in respond to nucleic acid challenge. This suggests that alleviating the STING-dependent inhibition of PUFA metabolism may result from, or be required for, adipocyte differentiation or functionality. Further, this also suggests that adipocytes may possess specific STING-independent cytosolic nucleic acid detection pathways. Thus, nucleic acid detection pathways and PUFA metabolism should be interrogated concertedly, at the cellular levels, within metabolic tissues, to uncover how they define tissue-specific immune responses and regulate tissue homeostasis, in particular in pathologies presenting with chronic STING activation. Within SENTINEL, we will combine state-of-the art biochemistry and molecular biology approaches, and cutting-edge omics tools, in vitro and in vivo to identify nucleic acid detection machineries and question the role of STING downregulation in metabolic cells. Finally, we will explore the impact of STING-dependent metabolic alterations in pathologies presenting with chronic STING activation. SENTINEL will thus chart an unexplored area of nucleic acid immunity (metabolic cell immunity), and reveal its impact on homeostasis and pathologies.

Keywords: inflammation nucleic acid immunity polyunsaturated fatty acids oxylipins type i interferonopathies adipose tissue adipocytes sting fads2 type i interferons
CarbOn Negative CemEnt fRom ulTra-mafic rOcks (CONCERTO)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: France,Belgium,Italy,Austria
Call: Towards cement and concrete as a carbon sink (HORIZON-EIC-2024-PATHFINDERCHALLENGES-01, 2024)
Start date: 2025-10-01
End date: 2029-09-30
Duration (months): 48.0
Total project cost (EUR): 5282106.63
EU funding (EUR): 4521199.7
Participants: 7
Project status: SIGNED

The majority of CO2 emissions associated with Portland clinker production originate from the calcination of limestone, a process necessary to extract calcium, the key element required for forming the main binding hydration phases. Unfortunately, most of the calcium found in nature is embedded in limestone. This project aims to explore hydraulic binders based on magnesium (instead of calcium) since this element is abundant in silico-magnesian ultramafic rocks, which are widely available. This approach thus eliminates the CO2 emissions associated with the decarbonization of raw materials during the production process. We have developed a groundbreaking, scalable process for producing silico-magnesian CO2-free cements from ultramafic rocks (CNRS pending patent). If decarbonized energy is used during production, the overall carbon footprint of this binder could be net-negative, as magnesium hydroxide formed during hydration could sequester atmospheric CO2 throughout the service life of the cementitious product via carbonation. The main goal of this project is to optimize the manufacturing process and performances of this hydraulic binder and to develop various applications based on it.

Keywords: silico magnesia cement,ultramafic rocks,low carbon binders,co2 sequestration,green energy
Copernicus responding to EU Cities Mission (CLMS-Cities)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Space
Destination: Open Strategic Autonomy in Developing, Deploying and Using Global Space-Based Infrastructures, Services, Applications and Data
Action type: Research and Innovation actions
Countries involved: Greece,United Kingdom,Spain,Portugal,Italy,Switzerland
Call: Copernicus for Land and Water (HORIZON-CL4-2024-SPACE-01, 2024)
Start date: 2025-02-01
End date: 2028-01-31
Duration (months): 36.0
Total project cost (EUR): 2087537.14
EU funding (EUR): 1999680.0
Participants: 8
Project status: SIGNED

The recently concluded H2020 project CURE prepared the ground for exploitation of Copernicus Core Services in urban planning. Achieving climate neutrality requires a city that has joint the EU Mission on “Climate-Neutral and Smart Cities” (the Cities Mission), to reduce the Greenhouse Gases (GHG) emissions from all sectors within the city’s boundary to net zero by 2030, including emissions within the city boundary, from: combustion of fossil fuels in buildings and facilities; combustion of fossil fuels for all vehicles and transport; and changes in land use (agriculture, forestry and other land uses). All the above are considered as Scope 1 GHG emissions (direct emissions) and the Copernicus Land Monitoring Service (CLMS), based on the CURE method for CO2 emissions monitoring, holds promise in aiding cities to achieve the ambitious goals of the Mission, by assisting in monitoring the efficiency of efforts to trace the advancement towards climate neutrality. The proposed project CLMS-Cities (Copernicus responding to EU Cities Mission) aims to improve CLMS with new elements and products, capable of being integrated into land planning decisions with regard to climate change mitigation at local scale. CLMS-Cities will contribute to CLMS evolution, as it is expected to lead to more evidence-based urban planning activities related to climate change mitigation, resulting in improved GHG emissions inventory methods and outputs to support cities to meet the Mission’s ambitious objectives. It will focus on the ten cities of the Mission that were recently (2023) labelled, providing the Mission’s community with spatially disaggregated environmental intelligence at a local scale and a proof-of-concept that urban planning and management strategies enhancing the GHG inventories can be supported by CLMS. CLMS-Cities method will be modular and scalable, delivering consistent products across the cities of the Mission and developing synergies between CLMS and third-party data sources.

Keywords: scope 1 ghg,co2 monitoring,urban planning,eu cities mission
The trail of sulphur: from molecular clouds to life (SUL4LIFE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Spain
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 2191875.0
EU funding (EUR): 2191875.0
Participants: 1
Project status: SIGNED

Sulphur is the tenth most abundant element in the Universe and is known to play a significant role in biological systems. Moreover, some sulphur compounds have been proposed as necessary catalysts to form amino acids in the interstellar medium. However, while the carbon and oxygen budgets have been extensively studied, sulphur is the only element whose gas-phase abundance is still uncertain by several orders of magnitude, hindering the usage of elemental sulphur abundance as a reliable tool to probe planet formation. This lack of information is due to the scarcity of observations, specially in protoplanetary disks, and the still large uncertainties in the sulphur chemical network. This project takes a decisive step to fix our knowledge of the sulphur chemistry with an innovative methodology that rests on three pillars: (i) To create an unprecedented database of high quality observations of sulphur-bearing molecules which allows us to trace the sulphur content from the natal molecular clouds to protoplanetary disks. Observations of the awarded IRAM Large Program GEMS have already provided part of this database. (ii) To perform ab initio calculations and laboratory experiments to estimate the key reaction rates that are needed to fix the sulphur network and make chemical models reliable. Now, we know that the chemical composition of planet-forming disks is to a large extent inherited from the earliest phases of star formation. (iii) To perform bi-fluid (gas+dust) 3D magneto-hydrodynamics simulations with chemistry coupled (chemo-MHD) to follow the chemical evolution of the material from the natal cloud to the planet-forming sites, and hence, to obtain accurate chemical predictions. This can be extensively done by using artificial inteligence to reduce the computing time. At the end, this project will disentangle how sulphur was delivered to protoplanetary disks, which is an essential step to understand planet formation and the emergence of life.

Keywords: astrochemistry,star formation
DURABILITY MODELLING OF COMPOSITE STRUCTURES WITH ARBITRARY LAY-UP USING STANDARDIZED TESTING AND ARTIFICIAL INTELLIGENCE (D-STANDART)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Netherlands,Germany,France,United Kingdom,Spain,Italy,Belgium
Call: Advanced materials modelling and characterisation (RIA) (HORIZON-CL4-2022-RESILIENCE-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 3794991.5
EU funding (EUR): 3330616.5
Participants: 13
Project status: SIGNED

Advanced composite manufacturing is becoming crucial in the global sustainable drive for a climate-neutral future as enabler of light-weight structures in, for example, the aerospace and wind energy sector. Their increased relevance has raised the importance of damage tolerance and durability of composite structures, currently dealt with time-consuming and inaccurate techniques. Hence the objective of D-STANDART is to develop fast and efficient methods to model the durability of large-scale composite structures with arbitrary lay-ups under realistic conditions (loads, environment). New test methodologies will be developed using generic specimens to correctly quantify material parameters that determine the durability of composites under cyclical loading. Material characterisation will be used in high-fidelity models to simulate defect growth in various lay-ups and at various scales as a function of cyclical loading and rate. To apply these models in an industrial design environment, D-STANDART will make use of Artificial Intelligence (AI) surrogate models, trained using test data from the project and historical test data to easily adapt to different design parameters and complex lay-ups, thereby accelerating the development, uptake, and commercialisation of advanced components. Two use cases have been selected to validate the modelled durability performance both in the aerospace and renewable energy sectors. Furthermore, circularity and sustainability will be assessed via dedicated life-cycle assessment, life cycle costing and cost-benefit analysis. This 36-month €5.6M valued action involves, 9 partners (3 universities, 2 RTOs, 2 industry, and 2 SMEs) from four countries (United Kingdom, The Netherlands, Germany, and France). The consortium will be supported by an Advisory Board formed of 6 End users embracing the value chain to validate requirements, guide on relevant approach to certification, and finally support results uptake, in tight alignment with EMCC.

Keywords: fatigue,composites,durability,modelling,standardization,manufacturing,artificial intelligence,life cycle assessment
BIO insulation materials for Enhancing the Energy performance of Buildings. (BIO4EEB)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Innovation actions
Countries involved: Germany,Spain,France,Belgium,Hungary,Netherlands,Lithuania,Italy,Czechia,Austria,Colombia
Call: Building and renovating by exploiting advanced materials for energy and resources efficient management (IA) (HORIZON-CL4-2022-RESILIENCE-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 8829674.63
EU funding (EUR): 6584313.5
Participants: 19
Project status: SIGNED

Buildings are responsible for approximately 40% of energy consumption and 36% of CO2 emissions in the EU. Deep Renovation of existing old buildings has the potential to lead to significant energy savings and a tremendous carbon footprint shrinkage. The current EU climate targets open an ample opportunity for exponential growth in the building thermal insulation materials market owing to the increasing number of new residential buildings and current deep renovation needs. The target is to support residential building´s construction performance extraordinary at all three hierarchical levels of construction parts simultaneously (building, component, material) by creating an amplified environmental impact and reducing additionally VOC emissions. BIO4EEB will apply non-hazardous bio-based material as e.g., Posidonia and various bio-based foams to develop and to proof the marketability of smart components for external and internal use as material application, pre-fab panels or windows. The efficiency and effectiveness is quite important to match with market demands and establish a unique selling proposition including a seven years RoI! BIO4EEB will close the increasing gap of insulation material shortage caused by the regular growing demand and the mismatch caused by lacking production potential and the outcome of the current energy crisis by boosting the use of available bio-based qualified materials as alternative solutions. The objective is to substitute using fossil resources for components and replace them at a comparable price value positioning. New business models utilizing the complete economic value chain open the market for bio-based BIO4EEB solutions and products uplifting the generic bio-based material use and qualifying their application at a circular economy approach for creating a much greener EU building and construction industry real estate stock.

Keywords: energy consumption,co2 emissions,non hazardous,bio based materials,cost effectiveness,