Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A Digital value chain Integration Traceability framework for process industries for Circularity and low Emissions by waste reduction and use of secondary raw materials (DigInTraCE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Partnership: Processes4Planet (co-programmed)
Countries involved: Greece,Spain,Denmark,Finland,United Kingdom,Belgium,Italy
Call: Circular and low emission value chains through digitalisation (Processes4Planet Partnership) (RIA) (HORIZON-CL4-2022-RESILIENCE-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 7645581.75
EU funding (EUR): 7645581.5
Participants: 27
Project status: SIGNED

DigInTraCE aims at the development of i)transparent and interoperableDecentralised Traceability platform using novel tracking, sensing and sorting techniques ii)Dynamically updated DPPschemes supporting certification and quality validation iii)AI based and decision making mechanisms for process and lifecycle optimisation iv)up-cycling, reuse and upgrade technologies for improved secondary raw materials use v)contribute to standardization, open and easy accessible data vi)business models creating new economic opportunities and learning resources for employees, promoting new digital skills and meeting regional social needs. The solutions are demonstrated in the sectors of a) Pulp & Paper focused in 2 cases: composite wood and furniture; and wood and Pulp & Paper and b) Chemicals focused in 2 cases: plastic parts from ICT equipment and automotive market; and polymers and textiles: in 4 countries, while composite wood case combines both the 2 main sectors.

Keywords: circularity,secondary raw materials,waste,traceability,digitalisation,digital product passport,industry,low emissions
Deciphering mineralogical and compositional properties of kidney stones: Implications for formation mechanism and potential treatments (MiKidSton)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,Switzerland,United States
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-11-18
End date: 2027-11-17
Duration (months): 36.0
Total project cost (EUR): 317205.6
EU funding (EUR): 317205.6
Participants: 3
Project status: SIGNED

Kidney stone disease is a vital health problem with a significant increase in prevalence worldwide. It is known that kidney stone formation is affected by medical conditions (i.e., diabetes), environmental factors, dietary habits, and gender, although the relationship between the stone mineralogical and chemical properties (e.g., crystal structure, elemental composition, etc.) to the urine and blood parameters are still unclear. Notably, there is limited information on how the kidney stone mineral phase is influenced by the organic compounds of body fluids during growth and dissolution. Likewise, the kidney stone isotope composition will be recorded during its formation, and subsequently can be used as an indicator of dietary habits, environmental factors, and identifying underlying diseases (e.g., diabetes, osteoporosis). MiKidSton aims to perform a systematic study, from macro- to nanoscale, on a large array of different types of kidney stone samples, to assess: i) the influence of the body fluid (urine and blood) parameters, as recorded in patients, on the characteristics of kidney stone biomineral phases, ii) the relationship of the chemical/isotope composition of kidney stones to their structure, and risk factors (e.g., diet, environment, diabetes, etc.), and iii) the controlling factors for stone formation and dissolution. These objectives will be achieved combining applicant’s expertise and that of PIs, from the two host institutions, on mineralogical and isotope analyses. The outcomes will shed light on connection between kidney stone structure, composition, growth and dissolution with physiological parameters for patients with urolithiasis, with important implications for accurate diagnosis and effective treatment strategies. Finally, MiKidSton findings will have important implications for future pathological biomineral investigation using cutting-edge techniques and, most importantly, for the study of other stone-related human diseases (e.g., gallstones).

Keywords: kidney stone,biomineralization,crystalline properties,dissolution precipitation,metal isotopes,diagnostic tools
Efficacy and Safety of a newly registered Artemisinin-Based Combination (Pyronaridine-Artesunate -PYRAMAX®) for the treatment of uncomplicated malaria in African pregnant women - Extended (PYRAPREG-extended)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Global Health EDCTP3
Action type: Research and Innovation actions
Partnership: EDCTP3 (JU-JTI)
Countries involved: Sweden,Burkina Faso,Congo, The Democratic Republic of the,Mozambique,Spain,United Kingdom,Netherlands,Mali
Call: Funding to successfully finalise EDCTP2-funded clinical trials that were negatively impacted by the COVID-19 pandemic (HORIZON-JU-GH-EDCTP3-2023-01, 2023)
Start date: 2024-05-01
End date: 2025-04-30
Duration (months): 12.0
Total project cost (EUR): 1539644.56
EU funding (EUR): 1539644.56
Participants: 8
Project status: SIGNED

PYRAPREG-extended aims to complete PYRAPREG project (PACTR 202011812241529) that determines efficacy and safety of Pyronaridine-Artesunate (PA) - PYRAMAX®, a newly registered Artemisinin-Based Combination, to treat uncomplicated malaria in African pregnant women, and to provide the necessary information to include this treatment in guidelines for management of malaria during pregnancy. The work includes a one year follow-up of children born to women included in the trial and pharmacokinetic (PK) sub-study. In addition, this project comprises an extensive capacity building component, including the training of PhD students. PYRAPREG activities started 1 March 2019, and were expected to be completed 28 February 2024. Intense site preparations were completed, but just before start of recruitment, COVID-19 pandemic started and significantly delayed trial implementation. Participant recruitment started early 2021 and was completed in 2023, with last delivery expected in Q3 2023. Final 1-year visit of children born to women included in the trial will occur mid-2024. Furthermore, sample analysis for QC, data cleaning and statistical analysis takes another 6 months to completion, allowing final report submission 2 months later (Feb. 2025). PK component was delayed due to late initiation of recruitment for the PK cohorts of patients. Last patient recruitment in the PK cohort is ongoing and PK sampling will finish Q3 2023. Participants follow up continues until all women delivered and all babies have reached the age of 1 year. PK bioanalysis is expected to be finished by February 2024. PK data cleaning and merging with clinical efficacy and toxicity data followed by population PK and pharmacodynamic modelling activities will then be initiated which will take around 9 months, leading up to a PK report by February 2025. PhDs encountered delays: students could not travel for training, and data collection for their studies was delayed and will be completed in PYRYPREG-extended.

Keywords: malaria,treatment,pyronaridine artesunate,pregnancy,safety,efficacy
Crop Efficient Red-Emitting Source (CERES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-01-01
End date: 2026-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

CERES aims at evaluating possible commercial applications of new protein-based down-converting red-emitting LED sources. Laboratory prototypes exhibit an extraordinary stability and efficiency as well as an easy-to-tune emission spectrum. This contrasts with the commercial low-energy emitting LED technology. CERES will focus on a validation phase including i) the optimization of the upscaling of protein production, the preparation of large-area protein-polymer color filters, and the assembly of red-emitting LED arrays and ii) the test in pre-industrial crop controlled environment agriculture growing boxes. This information will be paramount to realize a realistic market impact.
Multi-Modal and Multi-Aspect Holistic Human-Robot Interaction (FORTIS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Innovation actions
Partnership: AI-DATA-ROBOTICS (co-programmed)
Countries involved: Spain,Finland,Italy,Portugal,Slovenia,Ireland,Türkiye
Call: Industrial leadership in AI, Data and Robotics – advanced human robot interaction (AI Data and Robotics Partnership) (IA) (HORIZON-CL4-2023-DIGITAL-EMERGING-01-CNECT, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 10991641.63
EU funding (EUR): 10000000.26
Participants: 13
Project status: SIGNED

The European Union (EU) has experienced a decline in employment rates in various sectors such as industry, construction, and healthcare, with an aging workforce exacerbating the issue. To improve overall life standards and welfare, the EU's Horizon Europe programme is investing in emerging technology such as robotics and AI. FORTIS specifically focuses on providing a complete Human-Robot Interaction (HRI) solution that includes multi-modal communication and multi-aspect interaction. The goal is to develop a human-centric solution that addresses the needs of both the human workforce and the robots, allowing them to work together efficiently and safely. With cutting-edge research and advanced technology, this solution can help to mitigate the negative effects of an aging workforce on employment, working conditions, and welfare in the EU. The project will conduct three main pilots in the sectors of construction, infrastructure services, and manufacturing. These pilots will provide a total of 5 use cases to demonstrate the effectiveness and safety of the Human-Robot Interaction. Moreover, FORTIS will allocate a portion of the budget to finance pilots that allow civilians to interact with the robots in different settings, such as healthcare, public events, shopping centres, and grocery stores. This will provide an opportunity to evaluate the performance of the HRI solution in various real-world scenarios

Keywords: multi modal interaction,multi aspect interaction,holistic approach,social robotics,cultural robotics,ethical robotics,psychological robotics,verbal and non verbal communication,haptic feedback,ai
intelligent, innovative, integrative Water Systems (I3waterS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Ireland,Netherlands,France,United Kingdom,Italy,Colombia,Belgium
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 4594011.12
EU funding (EUR): 4594011.12
Participants: 24
Project status: SIGNED

The risk of water scarcity due to climate change and human activities is real. i3WaterS stands for Intelligent, Innovative, Integrative Water Systems and addresses the urgent need to optimize water resources management by providing a comprehensive solution to upgrade, optimally operate and maintain water distribution systems (WDSs). For the first time, a unique holistic approach will find the key interrelationships between external, day-to-day and extreme, factors and WDS failures, to advise actions and protocols to make WDSs robust and reliable. At research level, i3WaterS project focuses on the integration of data, specific expert knowledge and computational simulations tools, introducing the most advanced data-driven and artificial intelligent techniques beyond the State of the Art, that plugged in a newly developed intelligent decision support system (IDSSs), working as an umbrella for a set of 14 independent solutions that enables assisting the WDSs management into scientifically driven decision-making. The incorporation of artificial intelligence (AI) will help to increase the autonomy of some parts of the WDS, those suitable under a paradigm of maximum security, safety and robustness, and the project will take care to frame this autonomy in a global and general concept of intelligent assistance, including human validation in each steps where it makes sense 15 Doctorate Candidates will learn from a network of experts on network monitoring, data management, algorithms, AI, modeling, microbiology, ethics and industrial partners, and by participating in a specifically designed training programme, they will develop the required cross competencies to find, test and innovate over a solution that will be fundamental to meet the sustainable development goals on water. Just as important, i3WaterS provide a new generation of internationally connected professionals with unique skills for the development of thriving careers in the critical infrastructures.

Keywords: intelligent water systems,intelligent decision support,clustering,mas,digital twins
SUSTainable industrial DESIGN of TEXtile structures for composites (SustDesignTex)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Poland,Spain,Germany,Sweden
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2022-10-01
End date: 2025-09-30
Duration (months): 36.0
Total project cost (EUR): 1494625.0
EU funding (EUR): 1494625.0
Participants: 5
Project status: SIGNED

The SustDesignTex project general objective is to enhance networking activities and establish long-term strategic partnership between TUL (Faculty of Materials Technology and Textile Design), top-class leading counterparts at the EU level - 3 famous Universities, and the Polish company active in the field of the project results’ implementation. The general objective will be gained via building on the huge potential of networking for excellence through knowledge transfer in industrial design of innovative textile structures for composites, based on the joint implementation of a research microproject and a preliminary exchange of the best practice between TUL and the partners due to a set of coordination and support activities organized around the microproject. TUL, ITA, HB and UZ researchers will get acquainted with the real research interests and conditions of each other, train their skills and transfer knowledge on the new methodologies and equipment during short-term visits, expert visits, lectures, training sessions, joint research work, conferences and conducting of a joint research micro-project designing and assessing new Textile Reinforcement Composites (TRC). TUL also will get a huge institutional advancement in reserach management and administration, research project preparation, management and coordination, and develop the skills of its Early Stage Researchers via the Strengthening TUL research management marathon, roundtables, workshops and the Joint Summer School for TUL ESRs. The Industry-Research Dialog Platform and the Joint Research and Innovation Road Map launched in the project will create conditions for constant joint work with industrial partners and support gaing the goals of the Lodz Region Smart Specilization Strategy. The TUL team will acquire expertise in industrial design, processing textile structures and TRC from outstanding partners and become a Center of Excellence in the optimization of innovative TRCs.

Keywords: sustainable design,textile structure,technical textiles,textile reinforced composites,smart textiles,industrial design,design aesthetics,embroidery
A Neonatal anaerobic Gut-microbiome-on-a-Chip to decode bacterial colonization and infant gut T cell maturation (NeoGutChip)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2025-11-01
End date: 2030-10-31
Duration (months): 60.0
Total project cost (EUR): 1499996.0
EU funding (EUR): 1499996.0
Participants: 1
Project status: SIGNED

Developing a healthy host-microbiome symbiosis during the first 1000 days of human life is critical for lifelong health. Despite its importance, our understanding is limited and derives from animal studies or associative human trials. Therefore, there is a pressing need for an infant gut model to capture dynamic microbiome-epithelium-immune interactions in early life. In NeoGutChip I will develop and validate a first-of-its-kind in vitro human Infant Gut-Microbiome-Immune-on-a-chip model (iGuMI) that will faithfully simulate the complex anaerobic environment of the infant gut, which current models cannot achieve. I will capitalize on my cutting-edge GuMI and microbiome engineering experience, to ensure that iGuMI is microbiota- and immune-competent. I will use iGuMI to determine the impact of dietary and microbial factors (especially early bacterial colonizers) on the development and maturation of infant gut microbiota, the mucosal barrier, and immune cells, and unravel the keystone bacterial species and key genes driving these effects. I will realize these objectives through autologous coculture of infant colonic organoids derived epithelium and naïve immune cells in iGuMI. Using bacterial colonization and long-term coculture in iGuMI, I will identify a set of infant gut species driving the immune maturation, and key bacterial genes through RNA sequencing, metabolomics, and loss-of-function assays. Finally, I will investigate mechanism-guided intervention of the microbiota-immune axis in iGuMI to promote anti-inflammatory T cells and mucosal barrier function in infant gut. The successful completion of NeoGutChip will decode the strain-by-strain view of immune modulation by infant gut microbiota in early life and offer a molecular basis to rationally “design” new interventions that directionally promote immune health in babies. Finally, iGuMI can be further developed into a preclinical tool, representing a breakthrough for pediatric biology and medicine.
Paradigm shift in stroke: accurate diagnosis and evaluation of all treatment options in any hospital, at any time (Deepstroke-Acc)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-02-01
End date: 2025-01-31
Duration (months): 24.0
Total project cost (EUR): 3564878.75
EU funding (EUR): 2495415.0
Participants: 1
Project status: CLOSED

Methinks aims at revolutionising stroke diagnosis by empowering any hospital in the world to evaluate at any time all treatments options. Today, this is only possible using advanced medical imaging, which is available in around 50% of the hospitals. Methinks will do it with standard medical imaging, which is available 24/7 in any hospital also in rural areas and less developed countries. It leads to a reduction of time-to-treatment of up to 60 minutes: In stroke, “time is brain”, i.e. every minute counts and means that the patient can talk, walk, have cognitive capabilities… and live. It will also open a huge market opportunity, since our technology can run in all small, mid and major hospitals around the world. Bypassing advanced medical imaging is a paradigm shift that requires a large and expensive clinical trial. That is why we are considered as a high-risk company by VCs, needing the support of the EIC Accelerator. With the EIC support, we have the team to make that shift real.

Keywords: machine learning,statistical data processing and,stroke triage,endovascular treatment,large vessel occlusion,acute ischaemic haemorrhagic stroke,non contrast ct,deep learning,business model innovation,core assessment
Multibeam Integrated Optical Antenna Array Design for Free-Space Communication (MIMOSA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Greece,United Kingdom
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2025-02-28
Duration (months): 30.0
Total project cost (EUR): 211658.4
EU funding (EUR): 211658.4
Participants: 4
Project status: CLOSED

Humanity envisions the future world with cars driving themselves, the holograms in video conferences, augmented reality used everywhere to assist our daily life, and the list continues. The previous generation of mobile networks could not support such applications, and so the redesign of the network was decided with the 5th generation (5G) network standardization. In the redesigned network topology the signal processing previously occurred on the antenna site was moved to a central location and virtualized. This disaggregation allowed advanced functionalities and reduce the cost of antenna sites. On the other hand, it generated the need for a very fast and low latency connection between these disaggregated units (fronthaul) which cannot be supported with current wireless technologies and so only the fiber can be used. The MIMOSA aims to combine concepts from the RF world with integrated photonics for producing and demonstrating a compact electronically reconfigurable optical MIMO radiating system. The multibeam feeding network and the radiating elements, antennas, will be designed as a single monolithic photonic chip, which will reduce significantly the cost and form factor of the system. A system with at least 8 controllable beams will be designed. With the researcher’s background lying in the field of RF and wireless communications, his close collaboration with a host institute with strong expertise in the field of photonics provides the optimal framework for translating wireless needs into optically-enabled realities. Such a multibeam steerable MIMO system is expected to offer high availability links operating in real-life atmospheric conditions offering capacities higher than 50Gbps for up to 1000m link distance. The project will generate a framework for the implementation of high data rate optical wireless links capable to support 5G and beyond fronthaul requirements while reducing the cost, mass, form factor, and power consumption of the links.

Keywords: multibeam,phased array,free space optics,photonic integration,beamformer