Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Second and third funding line in 2016-2017 for the establishment of a European SST service provision function (2-3SST2016)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: Specific Grant agreement
Countries involved: Spain,Italy,Germany,Romania,Poland,Romania,Romania,France,United Kingdom,United Kingdom,Portugal,Portugal
Call: Improving the Performances of the SST at European Level (H2020-SGA-Space-SST3-2016-2017, 2017)
Start date: 2017-10-01
End date: 2020-12-31
Duration (months): 39.0
Total project cost (EUR): 27999088.5
EU funding (EUR): 27999088.5
Participants: 18
Project status: CLOSED

2-3SST2016-17 is the "Second and third funding line in 2016 and 2017 for the further development of a European SST Service provision function” project proposed under H2020 funding by the EUSST Consortium composed of five participating Member States in coordination with the EU SatCen. The project starts on 01/10/2017 and is composed of a Part I planned for a duration of 27 months until 31/12/2019 and Part II planned for a duration of 39 months until 31/12/2020, which indeed constitutes the end date of the project. The aim is twofold: (1) to continue to support the pooling of national resources on the SST objectives outlined in the Decision No 541/2014/EU in accordance with the Action Plan outlined in the EUSSTFPA and (2) continue to support the SST evolution needs in line with the objectives and challenges of Horizon 2020 related to protecting Europe´s investment made in space infrastructure. This will be performed by (1) consolidating the EUSST functions and SST capability at European level, supported by the implementation of an Integrated Management for all SST2016-17 project whose core elements are in 2-3SST2016-17 and (2) the improvement of the EUSST functions and capabilities, in accordance with the Action Plan outlined in the EUSSTFPA, consisting in both studies and upgrades of identified sensors controlled by the EUSST Member States with the aim to investigate and perform improvement of the EUSST functions and capabilities. The project is organised in 9 Work Packages (Project Administration, Projects´ Management, Governance, Consolidation of the sensor function, Consolidation of the processing function, Consolidation of the service function and user coordination, Studies on Future Environment and Trade-off, Studies on sensor and processing capabilities, Development Plan and Upgrades) each with a specific timeline and under the main responsibility of one Consortium partner and supervised by the Project Coordinator (DLR). An additional WP is set to comply with ethics requirements. The main project milestones are foreseen at M9, M15, M27 (Final Review for Part I) and M39 (Final Review for Part II and end of the project).
Social Investment Perspective in Work-Family Reconciliation Measures in Europe and East Asia (SIPEA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-10-01
End date: 2018-09-30
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

This project aims to explore the effects of social investment perspective on women and to identify effective work-family reconciliation measures in fostering social inclusion of women in the labour market and family. It adopts a mixed method approach to compare the social investment perspective in the work-family reconciliation measures in five European and two East Asian countries (Sweden, Germany, Hungary, the UK, France, Hong Kong and South Korea); and examines its relationship with women’s participation in the production and reproduction spheres. Systematic comparison of policy designs with the aid of country based policy grids, statistical analysis under the economic defamilisation index and state-led care-focused defamilisation index, semi-structural interviews with policy experts, secondment in non-academic organisations and dissemination activities will be conducted. Against the backdrop of the Lisbon Agenda and Horizon 2020, the social investment perspective has become a new social policy paradigm in Europe. It stresses on investing in human capital development, making efficient use of human capital and fostering social inclusion. It shares similarities with the productive approach in some East Asian countries which is regarded as important to economic success. This project will enhance the researcher’s comparative social research skills and cross-regional knowledge on related policies; add value to the hosting university’s leadership in international social policy study; promote knowledge transfer between the two regions; and derive policy suggestions on social inclusion of women in the labour market and family. It is built on the expertise of the supervisor and the researcher on welfare policies in Europe and East Asia; and will be an integral part of the work plan of the interdisciplinary East Asian Social Policy Research Network and Social Policy Cluster of the hosting University. This is a project to be considered by the Reintegration Panel (RI).

Keywords: women,work,family,care responsibilities,comparative social policy,defamilisation index
Regulation of (ADP-ribosyl)ation signalling in the DNA damage response: elucidating the function of a novel PARP1/ARTD1 interactor (PARPin)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

(ADP-ribosyl)ation is a dynamic post-translational modification synthesised by PARPs/ARTDs and regulates a diverse array of cellular processes, including the DNA damage response (DDR). The last decade has significantly improved our understanding of the key enzymes involved in (ADP-ribosyl)ation and the cellular pathways they function within. However, our understanding of how these enzymes are regulated is lacking and demands further investigation. In this proposal I seek to redress this. I have provided promising preliminary data identifying a novel uncharacterised interactor of PARP1 involved in the DDR. I expect that this novel protein will have a fundamental role in PARP1 biology in cells given that the two have co-evolved and form a protein complex in cells. I will implement newly available cutting-edge technologies, such as CRISPR-Cas9 and quantitative cell biology approaches, into an interdisciplinary strategy involving genetics, cell biology, structural biology and biochemistry. This strategy will allow me to address the following research objectives: (1) elucidate the function of this protein complex in genome maintenance (2) determine the atomic structure of the complex (3) define the physiological function of the protein complex using genetic mouse models. This timely and holistic approach will allow me to answer crucial outstanding questions related to the regulation of (ADP-ribosyl)ation signalling for the first time. Consequently, this will be the first mechanistic study of its function and therefore my research objectives are likely to yield original insights into novel aspects of (ADP-ribosyl)ation signalling. The objectives described in this proposal will enhance my potential to become an independent investigator by promoting the diversification of my technical competences through training at a world-leading institute and host laboratory. Therefore, the proposal is well aligned with the over-arching aims of the Work Programme.

Keywords: adp ribosyl ation,dna damage response,parp1,dna repair,genome stability,adp ribose,poly adp ribose,parp
Plants as sensors for standardization and calibration of controlled environment chambers (PlantSenseKit)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Ireland
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-09-01
End date: 2019-02-28
Duration (months): 18.0
Total project cost (EUR): 148619.0
EU funding (EUR): 148619.0
Participants: 1
Project status: CLOSED

Research in plant biology & crop breeding conducted in controlled environment chambers (CECs) require that observed differences in measured plant traits between or within CECs are attributable to the imposed experimental treatment or breeding protocol rather than to heterogeneity and/or poor accuracy in the monitoring of different chamber environmental conditions. To date, no commercial product has been developed which tests standardization of environmental conditions within and between CECs of the same manufacturer or between different manufacturers. The cost per chamber of deploying a full artificial sensor network to test for homogeneity of CEC conditions would be thousands of euros per CEC; a prohibitive cost for users and manufacturers alike. This Proof of Concept grant will develop and commercialize the first plant-based sensor kit for standardization and calibration of CECs used in plant research, commercial horticulture and by the international plant breeding sector (BAYER Crop Science, MONSANTO etc.) at one tenth of the cost of an artificial sensor network and with equal or better environmental sensing capacity. Commercialization of PlantSenseKit will be via a license agreement to a commercial partner and involve comprehensive market research, competitor analysis, and further technological refinement of the PlantSenseKit protocol, prototype testing & development of a business plan. This Proof of Concept grant will have a positive impact on society and economic activities by improving the performance of infrastructure used in food security and climate change research and by providing new jobs for Ireland via commercialization of PlantSenseKit.

Keywords: biosensor,plant science,chamber effects,plant growth chamber,stability test chamber,climate change,food security,indoor environment sector,seed companies,crop breeding sector
A novel instrument to identify chiral molecules for pharmaceutics and bio-chemistry. (CHIMERA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-05-01
End date: 2018-10-31
Duration (months): 18.0
Total project cost (EUR): 149375.0
EU funding (EUR): 149375.0
Participants: 2
Project status: CLOSED

This proposal aims at bringing to the market a revolutionary device to uniquely identify the chirality of molecules. An object is chiral if it differs from its mirror image, like our left and right hands. Chirality plays an extremely important role in two main fields: (1) Many drugs are chiral and selecting one of the two forms often enables the pharma industry to extend patent franchise, thus increasing profitability, and to improve the quality, safety and efficacy of the drug. (2) Researchers in the chemistry and biophysics labs use chirality as an indication of the 3D structural conformation of proteins and DNA, to study e.g. their secondary structure and stability under external stimuli. Spectrometers for measuring chirality already exist in the market. Many customers in the two aforementioned sectors could be interested in the new product we propose because it presents several advantages, namely a 2-fold reduction of the price, a 4-fold shrinking of the footprint and an increased information content. The ground-breaking concept (under patenting) behind this new spectrometer is to employ an ultra-stable interferometer to measure the chiral spectrum of molecules via a Fourier-transform approach and a heterodyne amplification of the signal. A first working prototype has already been realized and tested. The CHIMERA project has two main goals. (1) We aim at unleashing the innovation potential of the approach, by technically validating two prototypes in a pharmaceutical company and a biochemistry research lab, thus pushing the Technology Readiness Level of the system to the ultimate maturity required to approach the market, corresponding to TRL9. (2) We will design a complete exploitation plan, performing a thorough analysis of the market, developing a financing strategy, benchmarking our instrument against the competitors’ ones, profiling strategic partners and drafting a first version of a Business Plan to decide on the opportunity to found a start-up company.

Keywords: chirality,circular dichroism,optical activity,spectropolarimeters,spectroscopy,protein structure,enenatiomers
Development of a demonstrator for the Penetrating Particle Analyser (PAN) technology (PAN)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Switzerland,Czechia
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2019)
Start date: 2020-01-01
End date: 2023-12-31
Duration (months): 48.0
Total project cost (EUR): 2637500.0
EU funding (EUR): 2637500.0
Participants: 4
Project status: SIGNED

The goal of the project is to build a demonstrator for the Penetrating Particle Analyser (PAN), an innovative energetic particle detection technology to precisely measure and monitor the flux and composition of highly penetrating particles (> ~100 MeV/nucleon) in deep space. The application of PAN is broad and multidisciplinary, covering cosmic ray physics, solar physics, space weather and space travel. PAN will fill an observation gap of galactic cosmic rays in the 100 MeV/nucleon - GeV/nucleon region, which is crucial for improving our still limited understanding of the origin of cosmic rays, and their propagation through the Galaxy and the Solar system. It will provide precise information of the spectrum, composition and timing of energetic particle originated from the Sun, which is essential for studying the physical process of solar activities, in particular the rare but violent solar events that produce intensive flux of energetic particles. The precise measurement and monitoring of the penetrating particles is also a unique contribution to space weather studies, in particular to the development of predictive space weather models in a multi-wavelength and multi-messenger approach, using observations both space and ground based. As indicated by the terminology, penetrating particles cannot be shielded effectively. PAN can monitor the flux and composition of these particles precisely and continuously, thus providing real-time radiation hazard warning and long term radiation health risk for human space travelers. Once developed, PAN can become a standard device for deep space human bases and for deep space exploration and commercial spacecrafts, or as part of a space weather advance warning system permanently deployed in space. It can also be implemented on science missions to perform ground-breaking measurements for cosmic-ray physics, solar physics, planetary science and space radiation dosimetry.

Keywords: solar energetic particles,cosmic rays,space environment
Deciphering the RBPome in mosquitoes during virus infection (DRmov)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 2
Project status: CLOSED

The impact of mosquito-borne diseases has expanded dramatically in the last few decades to become an emerging global health problem, with around 1 billion new infections and 1 million deaths each year. In Europe there are more than 20 countries with established populations of invasive Aedes mosquitoes. Aedes mosquitoes are the principle vectors responsible for transmitting high-risk pathogens such as ZIKA virus (ZIKV), dengue (DENV), yellow fever virus (YFV), chikungunya virus (CHKV) and Venezuelan equine encephalitic virus (VEEV). Despite our vulnerabilities to mosquito-borne diseases, virus replication dynamics is still poorly understood especially in the invertebrate vectors. No treatment against these viruses targeting essential viral proteins are currently available. Thus, the World Health Organisation (WHO) and its Vector Control Advisory Group has urged for insect vector control. Vector control is usually performed through insecticides; however, resistance can emerge in mosquitoes leading to persistence of the disease. Therefore, virologists are turning their interests toward host factors that play essential roles in infection as novel antiviral targets, since they can potentially exhibit broad-spectrum efficacy. In particular, scientists envision that genetically modified mosquitoes with disrupted genes required for infection can be re-inserted into natural habitats or through targeting these genes by RNAi in order to control viral spread. As all mosquito-borne viruses have RNA genome, cellular RNA-binding proteins (RBPs) emerge as ideal targets for antiviral therapies, as they are key players in cellular and viral RNA metabolism . Thus, we propose here to profile comprehensively the compendium of mosquito RBPs (RBPome) using RNA-interactome capture (RNA-IC). Furthermore, we will apply different cutting-edge methods to identify the role of mosquito RBPs during virus infection.
Smart speech and language tools for children's development. (SMARTSLT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Ireland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-10-01
End date: 2020-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Smart speech and language tools for children's development. Kids Speech Labs is on a mission to ensure all children can develop their communication skills as early and effectively as possible. Children across the EU are spending up to 12 months on waiting lists for assessments and interventions for speech and language development. The major gap in the ecosystem is providing parents with tools they can use in the early stages of development to help understand their child's progress. Kids Speech Labs (KSL) are building assessment and training tools that use automatic speech recognition and artificial intelligence to assess, monitor and intervene in children's speech development. KSL’s smart technology and evidence-based solutions will be the first to provide parents and professionals in this industry with clinically validated digital tools to manage children’s speech development. The first goal of this project is to test the feasibility of deploying a light-touch speech assessment tool that can provide parents with unique insights into their child's speech development, generating further evidence of a real market gap and willingness to pay for solutions. The second goal is to validate our market assumptions, size, route to market and cost of acquisition. This project is the first step in developing a drastically new approach to providing solutions in speech and language development to address the inadequacies in the industry.
Female Paid Domestic Care Work: A Node of Social Reproduction (CareWork)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-04
End date: 2024-06-04
Duration (months): 24.0
Total project cost (EUR): 174167.04
EU funding (EUR): 174167.04
Participants: 1
Project status: SIGNED

CareWork is an anthropological study of domestic paid female care work for children and elderly persons in Bosnia and Herzegovina (BiH). Motivated by the global under-recognition of this essential activity as real labor and by recent global changes in its organization, my research goes beyond the almost exclusive anthropological theorization of care within kinship studies. Building on (socialist) feminist scholarly traditions on domestic work, which places care at the centre of political economy, CareWork investigates informal paid female domestic care work as a socially productive and reproductive relational activity in a dialectic relationship with broader social transformations in BiH and beyond. To enhance and fill gaps in current scholarship it uses an innovative methodology: it traces care work through ‘care clusters’ (various households differentially affected by it) and focuses on two connected sites—Sarajevo (primary site) and Austria (auxiliary site, a nearby top destination for BiH labour migration by carers)—to reconstruct the dynamics and dialectics of such work. This ethnographic study revolves around the following questions: a) How is this care work organized?; b) How does it shape up in relation to broader social processes (e.g. reconfigurations of labour and social security, of ethnonational relations, of migratory patterns) in light of processes of Europeanization?; c) What kind of effects/changes does this care work produce for the various stakeholders? In BiH global changes are particularly visible as it is marked by multiple formal—postwar, postsocialist, Europeanizing—transformations over the last 25 years. Tracing how social transformations converge in care work, CareWork affirms care as a central category of anthropological theory and demonstrates how social scientists can productively employ it as a prism for studying social transformations, as a deeply gendered node of social reproduction with retrograde and emancipatory potential.

Keywords: female domestic paid care work,social reproduction,social transformations,domestic division of labor,ethnic relations,social inequalities,war and postwar migrations,europeanization