Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A revolutionary solution for healthy Indoor Air Quality: Protecting buildings from urban air pollution while reducing energy use and lowering GHG emissions (Urecsys Urban)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2400000.0
EU funding (EUR): 2400000.0
Participants: 1
Project status: SIGNED

Urban air pollution is one of the world’s leading environmental causes of morbidity and death (WHO). It easily enters indoor spaces, where we spend 90% of our time, through the building’s HVAC (Heating, Ventilating, Air-Conditioning) systems. However, available solutions to tackle this urban air pollution inside buildings – based on air filters and purifiers – are ineffective against the most abundant toxic air pollutants which are too small for them. Additionally, existing systems for reducing energy consumption in buildings operate unaware of the entering pollution and actually make it worst. Urecsys is the first and only system able to remotely regulate the building’s HVAC, in real-time, protecting the building from the penetration of polluted air, drastically improving Indoor Air Quality (IAQ). In doing so, it also reduces energy consumption and lowers associated GHG emissions. The patent-protected technology is the first to calculate and predict pollution levels continuously every 10s. It is based on knowledge-intensive algorithms and innovative machine learning, and it uses smart external monitoring stations to collect data. Urecsys seamlessly integrates with the building management system to reach the HVAC, adhering with the most rigorous ventilation standards. To date, Urecsys has piloted its V1 system in over 40 buildings in the UK, IL and HU, showing reductions of 40-70% in hazardous indoor pollutants, reducing energy consumption and GHG emissions by ~10%, and saving 25% in energy costs. However V1 utilizes monitoring stations in each building and is thus less scalable and economical. In this project, with the help of the EIC, we plan to complete our Urecsys-Urban V2 commercial system, introducing our “urban model”, which uses a few monitoring stations per each 1-sqm urban area and is much more scalable and economical. We will then validate it in more pilots and launch it commercially in several European urban areas in 2026.

Keywords: smart building management technology indoor air quality real time regulation and optimization energy savings greenhouse emissions savings ghg climate mitigation pollution reduction ai ml
Innovative chemistry to illuminate biology: a new chemical conjugation technology to optimize drug discovery (Celtarys WomenTech)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Spain
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-07-01
End date: 2024-06-30
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Drug discovery faces two key challenges: on one hand, the sector has been losing competitiveness due to an increase in development costs and a reduction in sales; and on the other hand, the new therapeutical targets that appear every year, in part thanks to the potential of personalized medicine, demand urgently new research tools to efficiently identify new drugs acting on them. Celtarys proprietary technology provides a solution to both challenges: it is a new and disruptive patented chemical conjugation methodology that allows a qualitative and quantitative leap in the development of fluorescent chemical tools required to optimize early phases of the drug discovery process, thus reducing the attrition rate in later clinical phases and therefore optimizing the efficiency of the process. At the same time, our technology makes possible to develop in a costly and timely competitive manner customized fluorescent tools for any target of interest, unlocking the potential of newly identified therapeutical targets. Our technology is an efficient and environmentally friendly Lego-like semicombinatorial conjugation strategy, accelerating the design and synthesis of fluorescent probes with optimal pharmacological and photophysical properties for any target with therapeutic interest, outperforming radioligands and other available fluorescent probes, thus improving the complex and costly drug discovery process. Celtarys is led by two women, both founders of the company: Maria Majellaro, Phd in Chemistry, inventor of the patent in which our technology is based and CSO; and Sonia Martínez Arca, PhD in Biology, with previous experience in entrepreneurship and CEO of the company. Celtarys has been founded in 2021 and has secured a seed investment round. We count already with products in the market and our first clients. Our priority for the short term is consolidate our market position and undertake a growth phase, for which we seek support from the Women TechEU program.

Keywords: drug discovery,fluorescent probes,chemical conjugation,high throughput screening,research tools
MULTILX HOP-ON: Intercultural Encounters Through Multilingual Storytelling in Eastern Europe (MultiLX-Hop on)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Research and Innovation actions
Countries involved: United Kingdom,Hungary
Call: Hop-on facility (HORIZON-WIDERA-2025-03, 2025)
Duration (months): 20.0
Total project cost (EUR): 471400.0
EU funding (EUR): 471400.0
Participants: 2
Project status: CLOSED

Abstract: This project contributes to the Strategies to Strengthen European Linguistic Capital In A Globalised World (MultiLX) project by extending its scope through the involvement of participatory approaches to exploring young people’s communicative and digital practices in Eastern Europe. In contrast to highly migratory contexts, multilingualism in this region is mainly maintained by minority language speakers, who often form divided societies along intercultural lines, even within the same city. Our case study in Targu Mures, with a Romanian, Hungarian and Romani-speaking population, explores how a participatory youth project can transcend cultural and linguistic boundaries that are historically deeply embedded in the lives of urban dwellers. We will explore practices and ideologies related to local languages through the co-creation of digitally constructed stories that tell of encounters between members of, emically speaking, minority and majority groups, offline or online, past or present, and help us to understand how social cohesion can be strengthened. As the majority of educational institutions in the city are organised along ethnic lines, we are taking an inclusive approach by inviting participants from several high schools, with Romanian and with Hungarian as the main medium of instruction (as Romani-medium educational institutions do not exist). Our project engages young people in a multilingual participatory endeavour together to co-produce the stories they want to tell each other and their wider community. MultiLX-Hop on aims to generate new knowledge to inform language policy and strengthen linguistic capital for the future in Europe. It will take as its primary focus languaging by young people in everyday interactions, and in creative and digital environments.

Keywords: linguistic ethnography,minority language,digital storytelling,participatory sociolinguistics,collaborative writing,young people,language policy,arts based research
Vimentin intermediate filaments: the origin of stretchability and their direct interaction with actin filaments (VimAc)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-05-01
End date: 2026-04-30
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: SIGNED

Many cellular processes, such as cell shape, mechanics, and intracellular transport, rely on the organization of and interactions between cytoskeletal filaments (CFs). Intermediate filaments (IFs) are the least studied CFs, with little knowledge of their interactions with other CFs, particularly actin filaments (AFs). Vimentin, one of the most abundant members of the IF family, is upregulated during epithelial-to-mesenchymal transition and in epithelial cancers, its expression is associated with poor prognosis. Their hierarchical structure gives them great stretchability, which aids cells under large deformations. However, little is known about the deformation-induced unfolding of alpha helices and the parameters that drive it. This study focuses on understanding the origin of vimentin IF (VIF) stretchability by providing direct visualization of the unfolding of alpha helices within the VIFs and transition to beta sheets upon stretching under various conditions. Interactions of VIFs with AFs play an important role in cell mechanics and successful mitosis. Yet, if these filaments interact directly is still a matter of debate. The proposed project focuses on the interaction between VIFs and AFs to determine whether they interact directly at the filament level and, if so, what are the strengths of the interactions and their binding/unbinding rates. A combination of approaches and methodologies will be used, including in vitro reconstituted filaments, optical tweezers, tip-enhanced Raman spectroscopy, computer simulation. The knowledge gained from this project will help understand crucial physiological and pathological processes. The host and supervisor are well-equipped for this project, with the supervisor's expertise in understanding IF mechanics and function as well as interaction between CFs utilizing a multiscale biophysical approach. The PF will establish a unique niche in biophysics research and a robust CV for future grant applications and research positions.

Keywords: cytoskeletal filaments,vimentin intermediate filaments,vimentin filament stretchability,actin filaments,in vitro reconstitution,quadruple optical tweezers,computer simulations,ters
TOWARDS A NEW ZERO FOOD WASTE MINDSET BASED ON HOLISTIC ASSESSMENT (ToNoWaste)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Spain,Austria,Norway,Netherlands,Sweden,Greece
Call: Evidence-based decision-making to change social norms towards zero food waste (HORIZON-CL6-2021-FARM2FORK-01, 2021)
Start date: 2022-09-01
End date: 2027-02-28
Duration (months): 54.0
Total project cost (EUR): 5971408.0
EU funding (EUR): 5971408.0
Participants: 22
Project status: SIGNED

Food waste is a major problem: around 88 million tonnes of food is wasted annually along the EU supply chain, from primary production to consumption, with associated costs of €143 billion. The associated environmental impact is also huge: global food loss and waste is equivalent to 8-10% of total anthropogenic GHG emissions and costs around $1 trillion per year, and 30% of agricultural land is wasted. The situation may be even worse, as statistics indicate that 70% of all food lost or wasted by humans may be unrecorded because it originates from primary production or is used as animal feed. In parallel, the assessment of this problem remains unresolved, not only because it is extremely complex due to the lack of open access data and the absence of a standard methodology for comprehensive assessment in real food systems, but also because it affects the commitment of private entities that need to assess the cost-effectiveness and sustainability of food waste prevention and reduction (FWPR) solutions in order to act. ToNoWaste is a 48-month project in which 21 institutions from 7 countries collaborate to overcome this challenge with a multi-stakeholder and interdisciplinary approach that considers not only agronomic, economic, environmental and business model challenges, but also other cross-cutting aspects such as psychology, law and social innovation to fight also against gender and social inequalities. ToNoWaste will inspire market actors to use science and evidence-based assessment tools and data to make better decisions towards more sustainable food production and consumption patterns. It starts from research on what makes the best decision regarding FWPR actions in the fresh food value chain. It is an open innovation ecosystem designed to leverage previous findings for the identification of social, technical/environmental, economic, political/legal, ethical and demographic drivers and to collaborate with ongoing R&D actions to propose comprehensive FWPR solutions

Keywords: sustainability assessment
The Revolutionary Impact of Financing a Global War (1797-1825): Spanish American Bullion, British Foreign Aid, Irish Agents, and the Reconfiguration of Empires (UNWANTED)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain,Mexico,United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-11-30
Duration (months): 27.0
Total project cost (EUR): 236153.88
EU funding (EUR): 236153.88
Participants: 4
Project status: SIGNED

The EU is facing difficulties in her attempt to promote interdependence and peace in a context of geopolitical collision. Indirect intervention in external areas has produced unwanted effects. My research aims to investigate the unplanned consequences of external interventions by great powers using historical examples to provide insights for contemporary strategies. Modernity was built upon unplanned effects of strategic interference during the final clash among Atlantic empires, in the global Age of Revolutions. Intrusion in the Hispanic world allowed Britain to speculate on American coin and bullion to finance its Foreign Aid to Spain and Europe against Napoleon. By following Irish trans-imperial agents managing these speculations, the project looks at how global trade involving Latin America and changes in silver and gold flows transformed Britain's economic role with implications in Europe and worldwide. It links these financial initiatives to the best possible business in a revolutionary context, the arms trade. For the first time it shows how revolution in Spanish America ended up providing economic means to liberate Spain from French occupation through British aid and then to finance the struggle of other European nations against Napoleon, with the crash of the old imperial systems as an unwanted effect. This greatly accelerated the rush towards modern economy and empires. Through rigorous archival evidence this ambitious project aspires to kindle a deep-seated awareness of the past and present mechanisms and possible management of the unplanned revolutionary impact of strategic intrusion. Investigation in Spain(UPO) Mexico(UNAM) and the UK(UCL) and DEC activities like the creation of a DoNoSQL database, OA publications(3), conferences(3), syllabus, political brief, videos, cooperation between historians and political scientists(Side-NET) will help turn the tide of the present erosion of rule-based international relations as an unwanted effect of interference

Keywords: napoleonic wars,british foreign aid,silver and gold flows,irish diaspora,global trade,trans imperial mediators,imperial agents,age of revolutions
L.I.A.N.A.S. - Looking at Italian Africa Nature, Animals and Safari (L.I.A.N.A.S.)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States,Ethiopia
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-01
End date: 2028-12-31
Duration (months): 36.0
Total project cost (EUR): 396991.08
EU funding (EUR): 396991.08
Participants: 3
Project status: SIGNED

The overarching objective of the L.I.A.N.A.S. project is to provide the first in-depth analysis of the colonial and post-colonial relationship between Italy and the African landscape, namely the practice of big-game hunting and safaris as means of subjugating, and manipulating the colonial territory and nature. The exploitation of nature for propagandistic and economic purposes was a central aspect of the imperial rhetoric of European colonial powers. Nonetheless, a comprehensive examination of the ecological impact of Italian colonialism is still missing. The analysis will focus not only on the period of formal occupation of Italy's African colonies (1882-1941) but also on the subsequent phase, extending until the early 1970s, highlighting the long-term legacies in the ways of relating to African nature. Focusing on a repertoire of cultural products such as books, documentary films, and natural history collections dedicated to big game hunting trophies from Italy's Horn of Africa colonies (Eritrea, Somalia, and Ethiopia), the project aims to 1) reconstruct the tropes and discourses surrounding African animals created during the Fascist period, 2) highlight the long-term legacies of this way of viewing African nature in cultural products and museum displays, and 3) deconstruct these practices and engage the public as an integral part of the decolonization initiative. The three-year project will bring Dr. Falcucci to the University of Houston, the University of Florence, and, during a secondment, to the Natural History Museum of Addis Ababa. Falcucci, who has international experience in Italy, France, Belgium, the UK, and Spain, is confident that the Action will profoundly impact her career. She will acquire knowledge in the field of Environmental Studies from a global perspective and new Public History skills, disseminating results among specialists and a wider audience, enabling her to become a leading scholar in the field of Cultural History and Colonial History.

Keywords: italian colonialism post colonial studies environmental humanities animal studies colonial heritage history of collections natural history museums italian east africa safari culture
SPIN-V(E)CSELS FOR ULTRAFAST AND HIGHLY-EFFICIENT SPACE AND EARTH DATA COMMUNICATIONS (SpinDataCom)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: France,Germany,Netherlands,Croatia
Call: EIC Pathfinder Open (HORIZON-EIC-2024-PATHFINDEROPEN-01, 2024)
Start date: 2025-06-01
End date: 2028-11-30
Duration (months): 42.0
Total project cost (EUR): 2999250.0
EU funding (EUR): 2999250.0
Participants: 7
Project status: SIGNED

The explosive growth of available information requires a disruptive shift in the development of high-bandwidth and energy-efficient communication technology. At the same time, space-communication is critical with the acceleration of human activities in space. Laser-based space-light communication is attracting great interest due to the increasing demand for inter-satellite and ground-to-satellite communication. However, as the light intensity diminishes over long-distance, the development of a new light-coding method is crucial for reliable high-speed information transmission. It is questionable if future bandwidth requirements for earth and space communications will be met by conventional lasers, while keeping the overall power consumption manageable. SpinDataCom will overcome these limitations and revolutionize space and earth communications combining the advances in spintronics and semiconductor lasers with injected unequal number of spin up/down electrons. The electron spin imbalance in spin-lasers is transferred to the circular polarization of light which enables ultrafast polarization modulation, low-power consumption and highly-efficient information coding, implemented even on a single photon. Our approach can be transferred to existing fiberoptic networks, exceeding conventional transmitters in data rates and power efficiency. Gathering experts from 4 EU countries, SpinDataCom will build a disruptive proof-of-concept (TRL4) for spin-lasers, enabling ultrafast modulation via full electrical spin and magnetization control, to enable groundbreaking technologies for space and Earth data communication. This ambitious approach has potentially transformative impacts on society, economy, and environment due to its many applications on Earth and for space. With our Industrial Advisory Board, a strong communication, dissemination and exploitation plan, global visibility on SpinDataCom’s results will be ensured while enabling the transfer towards commercialization.

Keywords: spintronics spin lasers vertical external surface emitting laser optical telecommunication circular polarization space light communication magnetization switching