Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Hybrid neuroscience based on cerebral and muscular information for motor rehabilitation and neuromuscular disorders (HybridNeuro)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Slovenia,Spain,United Kingdom,Sweden
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 1105477.5
EU funding (EUR): 1105477.0
Participants: 5
Project status: SIGNED

The overall objective of the HybridNeuro CSA is to create the bases and support for long-term, well-structured and integrated research and innovation partnership in the field of hybrid neural-machine interfaces between Slovenia, a widening, developing European country and Sweden, United Kingdom and Spain, well established European countries with high research impact. The addressed hybrid neural-machine interfaces utilize noninvasively recorded cerebral and muscular signals and can be used for objective assessment, monitoring, and rehabilitation of neuromuscular disorders. The consortium is composed of University of Maribor (UM), Chalmers University of Technology (CUT), Imperial College London (ICL) and Technical University of Catalonia (UPC). All four partners are experts in biomedical signal processing. In the HybridNeuro project, UM’s expertise in muscle-machine interfaces (bottom-up approach to neuromuscular investigations) will be complemented by the excellence of CUT, ICL and UPC in emerging research avenue of brain-machine interfaces (top-down approach to neuromuscular investigations) and neurophysiology. High expertise in analysis of cerebral signals, brain-computer interfaces, evoked potentials, brain connectivity, and inverse cerebral modelling makes CUT, ICL and UPC the optimal leading institutions to enhance the scientific and technological capacity of UM. HybridNeuro aims to foster the development of research excellence at UM and in less-developed eastern Slovenian region through a) career forming of early-stage and senior researchers, b) increasing the attractiveness of UM for visiting researchers, c) improving project proposal and management capacity at UM, d) forming new and strengthening old collaborations between industrial, clinical and research institutions in Slovenia and abroad with UM and twinning partners in Sweden, the UK and Spain, and e) increasing the impact and visibility of neuroscience and neuroengineering in Slovenia.

Keywords: muscle machine interfaces,brain computer interfaces,motor rehabilitation,neuromuscular disorders
ATomicallY Precise nanorIbbons QUAntum pLatform (ATYPIQUAL)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: France,United Kingdom,Netherlands,Germany,Switzerland
Call: EIC Pathfinder Open 2022 (HORIZON-EIC-2022-PATHFINDEROPEN-01, 2022)
Start date: 2023-10-01
End date: 2027-03-31
Duration (months): 42.0
Total project cost (EUR): 1828288.75
EU funding (EUR): 1828288.75
Participants: 7
Project status: SIGNED

ATYPIQUAL’s main objective is to unveil a room temperature quantum technology platform based on a novel generation of Atomically Precise graphene nanoRibbons (APRs) and demonstrate its feasibility through technologically relevant devices. By definition, quantum technologies exploit the peculiar quantum properties of matter such as superposition, tunneling, and entanglement to develop tools and devices with new, non-classical functionalities. However, derived using conventional top-down techniques, these technologies lack atomic precision and are much more sensitive to environmental disturbances as compared to the electrical current switching in transistors. As such, they often require ultra-low temperature operation and impose important constraints on their general applicability. This makes their manipulation and integration to chip-scale substrates a major challenge. ATYPIQUAL is a highly interdisciplinary project that proposes a radically different high-risk bottom-up approach that uniquely offers to naturally 'hard-wire' complex quantum states into atomically precise carbon nanostructures: APRs. They exhibit novel physical properties beyond graphene such as topological quantum phases and spin polarization, all tailorable by their topology and edge structure. However, the demonstration of these electronic properties requires atomic precision control that can only be achieved through recent advances in bottom-up synthesis. We shall exploit atomically precise bottom-up on-surface synthesis to develop these novel advanced APRs offering on-demand multi-functionalities while relying on a single graphene nanoribbon backbone. By developing the required material processing and device fabrication steps and demonstrating the first technologically relevant feasibility examples, ATYPIQUAL will set the stage for a new quantum technology platform for atomically tunable multifunctional devices with applications in next-generation electronics, photonics and spintronics.

Keywords: nanoelectronics,quantum transport,graphene nanoribbons,spintronics
Many-body localization in two-dimensional quasiperiodic systems (2D-MBL-QPsyst)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Croatia
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-02
End date: 2026-05-01
Duration (months): 31.0
Total project cost (EUR): 161889.6
EU funding (EUR): 161889.6
Participants: 1
Project status: SIGNED

Systems that fail to thermalize over a long period of time are essential for both practical applications and fundamental science. For the former, such systems can serve as stable platforms for many future technologies that operate at the quantum level, such as information storage and quantum computing devices. For the latter, such systems can host exotic quantum phases of matter by suppressing thermal excitations that tend to destroy the order. One of the most famous classes of systems that resist thermalization is the class of many-body localized (MBL) systems. Until now, it has been confirmed both experimentally and theoretically that the MBL can exist in isolated one-dimensional systems, either random or quasiperiodic ones. In higher dimensions, the fate of MBL is still unclear. A famous avalanche theory predicts the instability of the MBL phase in higher dimensional random systems due to the rare regions of weak disorder. However, quasiperiodic systems do not contain rare regions, which might stabilize the higher-dimensional MBL. The main objective of this proposal is to investigate MBL in two-dimensional quasiperiodic systems. The goal is to show whether MBL in quasiperiodic systems can survive in dimensions higher than one. With a novel numerical approach, which will allow me to study the dynamics of large systems (~100 sites) and reach long times (several hundred hopping times), combined with analytical calculations, I plan to investigate the microscopic mechanisms behind the stability/instability of the MBL phase in two-dimensional quasiperiodic models. My research will (i) provide an insight into the interplay between interactions and quasiperiodicity in two dimensions, (ii) produce a new interesting range of localization phenomena, and (iii) present a highly tunable and experimentally accessible setting where slow dynamics and localization can be studied, and possibly exploited for technological applications.

Keywords: many body localization,quasiperiodic systems,two dimensional systems
Bite Ecology from Avian Kinematics and Shape (BEAKS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain,United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-02-02
End date: 2028-02-01
Duration (months): 24.0
Total project cost (EUR): 194074.56
EU funding (EUR): 194074.56
Participants: 2
Project status: SIGNED

Bite Ecology from Avian Kinematics and Shape (BEAKS) aims to answer the question, “What factors drive bird beaks to converge in shape and function?” Answering this question will not only deepen our understanding of evolutionary processes, but also provide practical guidance in conserving birds and their key functions in modern ecosystems. BEAKS will combine geometric morphometrics, finite element analysis, and phylogeneBite Ecology from Avian Kinematics and Shape (BEAKS) aims to answer the question, “What factors drive bird beaks to converge inshape and function?” Answering this question will not only deepen our understanding of evolutionary processes, but also provide practical guidance in conserving birds and their key functions in modern ecosystems. BEAKS will combine geometric morphometrics, finite element analysis, and phylogenetic modelling to map patterns of beak form and function evolution and their relationship with aspects like environment, body size, diet, and ectoparasite load. Dr. Miller, the candidate and an expert in avian ecology, and Dr. Marcé-Nogué, the supervisor and an expert in biomechanics, are an ideal pair to head this project and to enrich each other’s knowledge base while doing so. BEAKS will then use these established trends to predict future evolutionary trajectories in response to anthropogenic climate change and identify species whose ecological roles are most likely to be lost without intervention. This type of modelling is a specialty of Dr. Püschel, the secondment supervisor, and will be a valuable new skill for the candidate to learn. The host institution, The Universitat Rovira i Virgili, has established connections with educational institutions, news media, and policy makers to ensure the findings of BEAKS are communicated broadly and disseminated to those who can use the findings to preserve earth’s delicate ecosystems. This will further global efforts to preserve biodiversity, especially the EU’s biodiversity strategy for 2030.

Keywords: aves,biomechanics,birds,finite element analysis,functional morphology,geometric morphometrics,machine learning,phylogenetic comparative methods,phylogenetic modelling
Solution processable metal boride nanostructures for functional hard coatings in extreme conditions (BORNANO) (BORNANO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1874571.0
EU funding (EUR): 1874571.0
Participants: 1
Project status: SIGNED

Nanometer-sized solids such as nanocrystals (NCs) or layers that are one or few atomic layers thick offer advantages in fields from catalysis to optoelectronics. However, they are mostly incompatible with ‘extreme’ conditions, e.g. high levels of radiation, harsh chemicals, or extreme temperatures as found in aerospace or deep-sea infrastructures. To introduce nanomaterials to these conditions, I propose to combine innovative chemical design and surface engineering to create thin films composed of colloidal metal boride NCs. Based on the boron chemistry, these NCs promise unparalleled levels of hardness and wear resistance when processed in thin films, paving the way for the development of solution-processable coatings with many functionalities and resistance to extreme conditions. I will develop novel metal boride colloidal NCs, study their growth mechanisms and structure-property relationships, use solution processing to create thin films, and determine their mechanical and physical properties as functional materials in extreme conditions. Main innovations are:(1) as traditional methods have been found wanting in terms of purity, yield, and morphology control, I will introduce innovative high-throughput solid-state synthesis techniques, setting the stage for scalable and reliable production; (2) I will explore the atomic-level surface dynamics and develop suitable ligands to achieve stable suspensions through surface engineering; (3) I will test and validate methodologies to turn individual NCs into solid thin films with similar robustness and stability as bulk materials. BORNANO aims to introduce a new class of hard coatings and implement innovative processing methods for thin-film fabrication from colloidal suspensions. In parallel, it targets the fundamental understanding of the chemistry of metal boride colloidal NCs and their surface chemistry. These materials have potential applications in extreme condition technologies,from aerospace coatings to sensors.

Keywords: nanocrystals,colloidal chemistry,surface chemistry,metal borides,thin films,inks,solution processable,hard coatings
Mimic human complexity in a Beat to revolutionize the drug development (uBeat)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Italy
Call: Women TechEU (HORIZON-EIE-2021-SCALEUP-01, 2021)
Start date: 2022-06-01
End date: 2022-11-30
Duration (months): 6.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

BiomimX Beating organs-on-chips (OoC) are in vitro miniaturized and living replica of human organs and diseases, building upon cutting-edge technologies and human cells. Beating OoC provide a faithful replication of native human physiology integrating miniaturized 3D cell culture techniques, mechanical stimulation (uBeat®) and electrical recording capabilities (uSense). BiomimX’s proprietary key technology (uBeat®) supports 3D human cell cultures and integrates a controlled and tunable mechanical stimulation system. uBeat® leads to the generation of mature and functional miniaturized replication of human organs adequate to test compounds toxicity/functionality in a high-throughput fashion. Integration of uSense allows real-time evaluation of clinically relevant parameters from the established beating models. BiomimX’s Beating OoC represent a safer, more efficient and faster alternative to poorly predictable preclinical models to date available in the drug discovery pipeline (DDP). BiomimX already demonstrated the validity of its Beating OoC models in two critical fields of the drug discovery pipeline: uHeart (human beating heart-on-chip) has been applied as early predictor of drug functional cardiotoxicity, uKnee (first in vitro model of human OA) has shown its predictive potential for the discovery of new targets for an unmet pathology. Also thanks to the contribution of Women TechEU programme, BiomimX aims at demonstrating the unprecedented potential of its disruptive innovation in reshaping the market of drug development, by i) boosting technological aspects (i.e. through an intensive industrialization process of BiomimX patented technologies) and ii) proving the versatility of its innovation and its capacity to adapt to a manifold of indications and market spaces. In line with the 3R principle, BiomimX final vision is to reduce and eventually replace animal experimentations within the next 15 years.

Keywords: organs on chip drug screening preclinical models,fundraising
DEploying Ecosystemic solutions to imProve soil Health and uncOveRing subsoil functIons in the critical ZONe (DeepHorizon)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Soil health and food
Destination: Soil health and food
Action type: Research and Innovation actions
Countries involved: Belgium,France,Germany,Poland,Denmark,Spain,Czechia,Switzerland,United Kingdom,Italy,Greece
Call: Discovering the subsoil (HORIZON-MISS-2023-SOIL-01, 2023)
Start date: 2024-10-01
End date: 2028-09-30
Duration (months): 48.0
Total project cost (EUR): 5860203.75
EU funding (EUR): 5860203.75
Participants: 20
Project status: SIGNED

Life on Earth thrives on the foundation of healthy soils, including topsoil and subsoil. While extensive research has focused on the topsoil layer, the subsoils remain largely unexplored. By bringing together key experts and practitioners, DeepHorizon aims to unlock knowledge of the subsoil in critical zone in order to deploy ecosystemic solutions to improve subsoil functions for soil health. DeepHorizon goal is to develop tools that will enable practitioners, land managers and policy makers to access subsoil properties, subsoil functions, soil health indicators and financial decision support tools to promote sustainable subsoil management. Through a multi-actors approach from farmers to policy makers, DeepHorizon will (1) collect and use existing data on subsoils; (2) generate new knowledge through extensive subsoil sampling and experimental effort (40 core sites) to measure biological, physical and chemical properties of different subsoils with contrasted management, and different soil type (organic/mineral), land uses (forest, grassland, cropland and semi-natural areas) and climate ; (3) use innovative process-based models to quantify actual and potential subsoil functioning, and soil health indicators; and (4) involve practitioners and stakeholders in the project through living labs and partner networks to co-create, test and deploy innovative solutions to improve subsoil functions over 100 test sites across Europe. By creating its own community of end-users and key stakeholders, DeepHorizon will ultimately promote sustainable management practices, policy-incentives and guidelines at EU level for increasing carbon storage and ecosystem services in subsoils and disseminate and communicate materials to a better understanding of subsoil relevance to the general public. By improving knowledge and consideration of subsoils in general, DeepHorizon will enhance soil health and pave the way for a more sustainable and resilient environment in Europe.

Keywords: ecosystem services,indicators,soil health,soil physics,soil modeling,sustainable land management
Securing local supplY chains via the development of new Methods to assess the circularity and symbiosis of the Bio-bAsed industrial ecosystem enhancing the EU competitiveness and resource independence (SYMBA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Coordination and support actions
Countries involved: Italy,Spain,Belgium,Germany,Netherlands
Call: Symbiosis in the bio-based industrial ecosystems (HORIZON-CL6-2023-CIRCBIO-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 1657297.36
EU funding (EUR): 1497842.0
Participants: 10
Project status: SIGNED

The SYMBA project aims at creating a new and innovative IS method to be replicated within EU according to the local/regional bio-based industrial ecosystem. SYMBA will implement a user-friendly and accessible AI database suggesting regional IS innovative processes to create zero-waste value chains, ensuring more local supply chains; a better distribution of economic and social benefits among the stakeholders and an increase in the economic value of final products. SYMBA solution, aligned with the EU Bioeconomy Strategy, is based on a threefold approach: 1) Creation and validation of new IS methodology for the bio-based sector, starting from existing knowledge and lessons earned from SYMBA consortium partners. 2) Individuation of criteria to select regional hubs 3) AI database including Monitoring tools, waste relation matrix, networking and cooperation with ongoing EU and local networks. The partnership has been intentionally selected by its expertise, network with key external stakeholders and geographical reach, bringing together 5 EU countries (IT, ES, BE, NL, DE) to consolidate the maximum outreach of the initiative. It consists of 9 partners with complementary competences: 4 RTD centers (CIRCE, CTB, AIMPLAS; CET); 1 large industry (NVMT); 1 pilot facility (BBEPP); 1 innovative SME (ENCO) and 2 networks (CKIC and ICLEI) with a valuable background in applying IS approach in the bio-based sector, providing services to companies and creating awareness and networking among citizens, policy makers, EU initiatives. Through the involvement of different industrial sectors: agri-food (NVMT); packaging (AIMPLAS); wastewater (CET); textile (CTB); waste valorisation (BBEPP), SYMBA will demonstrate how to shift from a linear to a circular economy contributing to deliver bio-based solutions with reduced environmental impacts on soil, water and air quality.
Evolution of sperm conjugates: does sperm competition drive the cooperative behaviour of sperm? (SPECO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Finland,Australia
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-04-01
End date: 2028-03-31
Duration (months): 24.0
Total project cost (EUR): 226276.8
EU funding (EUR): 226276.8
Participants: 2
Project status: SIGNED

Sperm conjugates, where multiple sperm cells attach to each other and move as a group, have been described in a wide range of taxa and could have significant impacts on the fertilization process, but understanding of their function is limited. Effective sperm cooperation through these conjugates could have evolved as an adaptation to sperm competition between multiple males, but this hypothesis has not been tested in insects, which have some of the largest reported sperm conjugates in animals. Bushcrickets have been well studied regarding species-specific variation in the level of polyandry and sperm competition. Large sperm conjugates (‘spermatodesms’) are also a common feature of this taxon, making it an ideal system to test the link between sperm conjugates and sperm competition. I will investigate this connection using within-species approaches, with controlled mating trials and sperm staining, as well as phylogenetic controlled studies, testing the link between the level of polyandry and spermatodesm traits between species. Finally, guided by the insight from these results I will construct a theoretical model to gain understanding into selection pressures that may have led to the evolution of conjugated sperm. The results will significantly improve our understanding of the evolutionary importance of collaborative behaviour of sperm, which has been largely unstudied until now. My supervisor, Dr Jussi Lehtonen, is an internationally renowned researcher who is experienced in developing mathematical models on sexual selection and sperm competition. The project includes a secondment hosted by Prof. Leigh W. Simmons, a leading expert in insect sperm biology. I, the candidate, am an expert on behavioural ecology, experienced in conducting mating trials in bushcrickets and phylogenetic analysis on insects. The project will strengthen my scientific skills and the future career prospects, as well as expand and complement the research of the host institution.

Keywords: sperm competition