Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
EXPeriment driven and user eXPerience oriented analytics for eXtremely Precise outcomes and decisions (ExtremeXP)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: World-leading Data and Computing Technologies
Action type: Research and Innovation actions
Countries involved: Greece,France,Czechia,Spain,Cyprus,Norway,Netherlands,Slovenia,United Kingdom,Germany
Call: Methods for exploiting data and knowledge for extremely precise outcomes (analysis, prediction, decision support), reducing complexity and presenting insights in understandable way (RIA) (HORIZON-CL4-2022-DATA-01, 2022)
Start date: 2023-01-01
End date: 2026-02-28
Duration (months): 38.0
Total project cost (EUR): 10011820.0
EU funding (EUR): 10011820.0
Participants: 21
Project status: SIGNED

Extreme data characteristics (volume, speed, heterogeneity, distribution, diverse quality, etc.) challenge the state-of-the-art data-driven analytics and decision-making approaches in many critical domains such as crisis management, predictive maintenance, mobility, public safety, and cyber-security. At the same time, data-driven insights need to be extremely timely, accurate, precise, fit-for-purpose, and trustworthy, so that they can be useful. ExtremeXP will handle the complexity of matching extreme needs with complex analytics processes (i.e., processes that involve and combine ML, data analysis, simulation and visualization components) by placing the end user at the centre of complex analytics processes and relying on user intents and running experiments (i.e., trial and error) to prune the vast solution space of possible analytics workflows and configurations i.e., “variants”. Its main goal is to create a next generation decision support system that integrates novel research results from the domains of data integration, machine learning, visual analytics, explainable AI, decentralised trust, knowledge engineering, and model-driven engineering into a common framework. The overarching idea of the framework is to optimise the properties of a complex analytics process that the end user cares about (e.g., accuracy, time-to-answer, specificity, recall, precision, resource consumption) by associating user profiles to computation variants. The framework is envisioned as modular and extensible, orchestrating different services around an Experimentation Engine: Analysis-aware Data Integration, Extreme Data & Knowledge Management, User-driven AutoML, Transparent & Interactive Decision Making, and User-driven Optimization of Complex Analytics. The framework will be validated in five pilot demonstrators.

Keywords: experimentation,user experience,
Head to tail imaging of fluorescent carbon nanotubes for the characterization of the brain extracellular space (NanoHeadTail)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 3
Project status: SIGNED

The NanoHeadTail proposes a novel and original approach combining fluorescence microscopy and nanotechnology to resolve the morphological and rheological properties of the brain extracellular space (ECS) at the nanoscale. Current methods allow to determine the local dimensions and fluidity of the ECS, but they do not allow to resolve its structural complexity and are limited to an analysis in 2D. This project proposes the simultaneous monitoring of the position, the translational and rotational diffusion of fluorescent probes over time and in 3D, allowing to determine the volumetric structure, fluidity and inner organization of the ECS locally. For that, a novel type of asymmetric probes will be designed based on the localized functionalization of single-walled carbon nanotubes with fluorescent color centers at their ends, analyzed using a custom cutting-edge fluorescence microscope and tested in live brain tissues from mice models of the Parkinson’s disease. The applicant will bring his strong expertise in the photophysics and chemistry of carbon nanotubes, critical for the preparation of the probes. In parallel, the fellow will gain a high-level hands-on training on optics assembly, super resolution microscopy and single particle tracking, imaging analysis and neurosciences. The project will be performed at the IOGS-LP2N (CNRS/Univ. Bordeaux), a leading French research institution, under the supervision of Dr. Laurent Cognet expert in the single particle tracking of nanoobjects. The proposal contains well-identified work packages which will ensure efficient science development but also project management, career development, training, technology transfer and communication. The fellow’s expertise, the hosting lab, the infrastructure, facilities and the mentoring will guarantee the successful execution of the NanoHeadTail goals and will allow the applicant to reach a high level of professional maturity and to develop his career as an independent researcher.

Keywords: single particle tracking,single walled carbon nanotubes,neurophotonics,fluorescence microscopy,super resolution microscopy,near infrared fluorescence,brain extracellular space
The rethinking of dyeing as fundamental and applied research training for sustainable fabric and food processing: Development of novel biogenic dyes for classical and innovative application (DyeAnotherWay)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Austria,Finland,Germany,Belgium,Sweden,United Kingdom,United States,Brazil,Portugal,Spain,France
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2025-10-01
End date: 2029-09-30
Duration (months): 48.0
Total project cost (EUR): 3889775.67
EU funding (EUR): 3635712.0
Participants: 17
Project status: SIGNED

DyeAnotherWay aims at providing Doctoral Candidates with the skills necessary to lead the textile and food industries into a greener future by developing new sustainable dyeing methods exploiting bacterial genetic resources in an innovation-oriented way using cutting edge technology. The co-operation between the professional textile industry, commercial suppliers of analytical and biotechnological services, and scientists from nine Universities from ten countries addresses urgent needs in the non-academic sector and scientific hotspots in microbiology, bioeconomy and the textile and food industry simultaneously. Bacteria-based pigments, are the common research platform in combination with a broad spectrum of disciplines ranging from microbiology, chemistry, biotechnology, biochemistry, molecular biology, and bioinformatics to textile processing and market research. This will, in the near future, make a range of fully characterised biogenic dyes commercially available to the industry for use in dyeing both conventional and new textiles, allowing the industry to wean itself off petrochemical dyes in an economically viable way. The dyes will potentially find application beyond the textile and food industry, thus allowing many fields to benefit from their low carbon footprint production and their compatibility with human and environmental health. The 12 Doctoral Candidates will obtain multi- sectoral training in the relevant disciplines. In addition, training in research management, communication/presentation, creativity and entrepreneurship will provide key transferable skills for public and private sector employment, thereby maximizing the impact on the research and training on the fellows’ careers. The diversity of dissemination and communication activities guarantees the DCs' exposure to stakeholders in every sector and will help shape the future of education in this field.

Keywords: colour,fabrics,food,ecological dyeing,organic dyeing,bacterial dyes,native producers,bioeconomy
Smart Electronic Olfaction for Body Odor Diagnostics (SMELLODI)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany,Israel,Finland,Czechia
Call: EIC Pathfinder Open 2021 (HORIZON-EIC-2021-PATHFINDEROPEN-01, 2021)
Start date: 2022-04-01
End date: 2025-09-30
Duration (months): 42.0
Total project cost (EUR): 3263781.25
EU funding (EUR): 3263781.0
Participants: 6
Project status: SIGNED

Olfaction provides a wealth of information about our environment. Partner selection and disease detection are just two examples of the versatility of our olfactory system. Despite its important role, the digitization of the olfactory sense is still in its infancy compared to vision and hearing. In particular, storing olfactory profiles, their on-demand synthesis, and transmission are critical barriers to broader use of the specific and unique information provided by olfaction. Experienced physicians, for example, rely on their sense of smell as an additional diagnostic tool: body odor profiles change over the course of metabolic and inflammatory processes, making body odors particularly useful for disease diagnostic and health monitoring. Thus, neurodegenerative or inflammatory diseases can be detected at an early stage with the help of the sense of smell. Based on the stringent combination of an innovative biomimetic sensor technology, a psychological understanding of odor perception, and the application of machine learning techniques, SMELLODI will develop a science-to-technology breakthrough that will ultimately enable the detection and on-demand synthesis of odors. Our interdisciplinary team combines expertise in nano and sensor technology, clinical olfaction and psychological perception, chemistry, and material science. SMELLODI will develop technologies for remote medical diagnostics and for assisting individuals with olfactory disorders by visualizing information about their body odor. Our proof-of-principle odor display will demonstrate for the first time the digitization, transmission, and synthesis of body odors over time and space. The market prospects for intelligent electronic odor recognition are enormous, ranging from mass-market devices to highly specialized diagnostic equipment. Our project will prepare the ground for the necessary innovations to make the technology available to address the societal and economic challenges of the future.

Keywords: olfaction,electronic nose,odor display,perception,biomimetic functionalization,carbon nano tubes,diagnostic,body odor,volatilome
Advanced ingestibles for probing the nexus between gastrointestinal functions and physical/mental well-being in animals and humans (DeepDive)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-01-01
End date: 2025-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Expanding on the “eHONESTY” ERC project about the link between body and moral decisions, the DeepDive PoC proposal aims to explore the neglected role of deep-body signals in modulating physical/mental health in humans and animals through the radically new approach of using ingestibles for mapping gastrointestinal (GI) physiology. Crucially, although the market of ingestible devices is burgeoning, none of the existing products has the features needed for probing the link between GI dys/functions and physical/mental well-being in humans and animals. To fill this outstanding gap, the DeepDive project aims to develop and test a class of ingestibles that can capture from different tracts of the GI system (e.g., stomach, small/large intestine), physiological signals like endoluminal pH, pressure, and temperature with unprecedented accuracy and precision; and, remarkably, add causation to correlation by recording the GI neurons' activity before and after their electrical perturbation. The inert capsules will be produced by: i) assembling specific components created using 3D printing and ii) integrating a number of microscopic components ranging from solid state pH, temperature, and pressure sensors to A/D–D/A Microconverter and RF Radio 2.4 GHz, in a sub-centimetric space. GI functions at rest and in conditions of social stress will be tested in piglets using the new ingestible and in humans using commercial pills. All the steps towards patenting and obtaining permission for use in humans of the novel ingestible will be taken, and existing contacts with industrial partners and biomedical devices approval offices will be strengthened. Given the link of gastroenterology with physical/mental dys/functions and human/animal well-being, the project will have significant benefits at neuroscientific, medical, and societal levels. Moreover, since the global market of ingestible sensors is expected to exceed $14 billions by 2026, DeepDive will likely have key economic implications.
Epigraphic centres of medieval Scandinavia: Latinization and re-vernacularization of the linguistic landscape 1050–1550 (EpiCentres)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Norway
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 1499197.0
EU funding (EUR): 1499197.0
Participants: 1
Project status: SIGNED

EpiCentres investigates the development of written culture in medieval Scandinavia (1050–1550), a context uniquely characterized by centuries of interactions between different languages and alphabets. While the evolving relationship between Latin and the vernacular influenced the development of all western European literate societies, in Scandinavia, Latin and the Latin alphabet were introduced in the 11th century into a pre-existing 900-year-old written tradition comprising thousands of inscriptions in the local vernacular languages and in the runic alphabet. Rather than replacing this native tradition, the Latin one coexisted with it for 400 years, resulting in a written culture shaped by overlapping processes of spread of Latin alongside the runic tradition, increased Latinization and decline of the runes, and ‘re-vernacularization’, the increasing use of the Scandinavian languages but written in the Latin alphabet. EpiCentres will analyse these processes by studying an almost entirely overlooked body of texts comprising approximately 1500 Latin-alphabet inscriptions, together with 2500 runic inscriptions from the same period. The project pursues three aims: 1) Mapping the evolving production of inscriptions in different languages and alphabets through geospatial analyses and making the vast corpus of Latin-alphabet inscriptions publicly and digitally available for the first time; 2) Developing a holistic methodology for studying Scandinavian epigraphy, focusing on the intersections of textual, orthographic, palaeographic, and visual practices of epigraphic traditions in different languages and scripts, uniting previously compartmentalized disciplines of runic, Old Norse, and Latin studies; 3) Proposing a new explanatory model for the use of Latin and the vernacular, reinterpreting their relationship within a sociolinguistic and social semiotic framework to understand the sociocultural premises and implications of evolving language and script choices.

Keywords: epigraphy medieval scandinavia runic inscriptions medieval latin historical sociolinguistics historical multilingualism latin inscriptions latinization
Joint Understanding and Analysis of clade I monkeypox epidemiology, evolution and immunology in South Kivu (JUA KIVU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Global Health EDCTP3
Action type: Research and Innovation actions
Partnership: EDCTP3 (JU-JTI)
Countries involved: Netherlands,Congo, The Democratic Republic of the,Spain,Rwanda,Denmark,Tanzania, United Republic of,Burundi
Call: Mobilisation of Emergency funding for Mpox outbreak research response (HORIZON-JU-GH-EDCTP3-2024-Mpox, 2024)
Start date: 2024-10-01
End date: 2026-09-30
Duration (months): 24.0
Total project cost (EUR): 1250000.0
EU funding (EUR): 1250000.0
Participants: 8
Project status: SIGNED

We recently described the novel clade Ib mpox virus from Kamituga, South Kivu, which fast spread in the region and severe symptoms are the reason for the emergency call for mpox research. Further information on its transmission, origin, adaptation, the protective serological response from different population groups, possibilities to improve frontline treatment and possibilities for early detection of the extent of the outbreak is urgently needed to combat the outbreak. The research proposed here is in close collaboration with local researchers and authorities and linked with already established capacity building projects covering DRC, Burundi, Rwanda and Tanzania. We aim to 1) determine the adaptation of the novel clade by performing on-site whole genome sequencing on a unique already available isolate collection covering the duration of the outbreak, 2) identify the origin of this clade by investigating bush meat and hunters, 3) investigate the importance of co-infections and the potential usefulness of real-time metagenomic sequencing treatment guidance, 4) determine the extent of the outbreak by serological and pit latrine surveillance in the cross-border regions of DRC, Burundi, Rwanda and Tanzania and 5) determine the specific immunological response to the novel clade from selected populations. We are uniquely positioned to conduct the proposed research, as we have the necessary technical skills and competences through on-going activities, all ethical permission are in place to investigate mpox as a disease X scenario and we have established collaboration with cross-border health authorities. We expect to create knowledge on the evolution and epidemiology of the novel clade, information on the expected immune response, and novel methods to perform early warning surveillance and improved treatment including of secondary infections. Almost all data generation and analyses will be performed locally, thus also ensuring capacity building for future epidemics.

Keywords: mpox,metagenomics,pandemic preparedness,local capacity building,early detection,virus evolution,epidemiology,co infections
Biopolitics, Sovereignty and Political Conflict (BSPC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Finland,Australia
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 276864.48
EU funding (EUR): 276864.48
Participants: 2
Project status: SIGNED

This project is a philosophical attempt to address the question of political conflict. At this time what seems to matter most in the escalation of conflicts around issues like gender, minorities and the COVID-19 pandemic is the biological life of individuals and populations. This is problematic for the reason that politics is structurally ambivalent about natural life: it is productive and affirmative, on the one hand, and, on the other, it is lethal and negative. There is a wide agreement that this ambivalent relation of politics to life stems from how biopolitical power intersects with sovereign power, the power over life with the sovereign right of death. While studies in biopolitics often take this enigmatic nexus as the point of reference for further considerations and subsequently emphasise the imminence of the problems with violence and pacification, this project aims to go further than that by drawing upon Jean-Luc Nancy’s idea of technology as the condition of biopolitics to deconstruct and recast affirmatively the knot of biopolitical power and sovereign power. This re-articulation I argue provides a novel angle from which to review the conceptions of resistance and to consider the grounds of political conflict. To show the affirmative value of political conflicts, I apply my developed concepts to examine populist polarization and neoliberal pacification that beset biopolitical liberal democracies today. The 24 months or outgoing phase of this project will be carried out at Deakin University under the supervision of Prof. Vanessa Lemm. I will return to the University of Jyvaskyla for 12 months under the supervision of Prof. Mika Ojakangas.

Keywords: deconstruction,continental philosophy,jean luc nancy,biopolitics,foucault,political conflict,sovereignty
Actually Existing Development: Twentieth Century International Development and the Global South (DEVHIST)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 1970046.0
EU funding (EUR): 1970046.0
Participants: 1
Project status: SIGNED

International development—the cross-border transfer of funds and expertise for developmental purposes—formed a core plank of the twentieth century international system. But we still know very little about the grassroots dynamics of international development in the twentieth century. DEVHIST will be the first project to systematically examine the encounters between individuals, groups and worldviews that both attended and often reshaped international development at points of implementation across the Global South, from the 1950s to the 1990s. Taking the site of implementation as a dynamic space of renegotiation, this project will expose and interrogate the gap between planned and Actually Existing Development in the twentieth century. Uncovering the complex negotiations that remade international development projects at the point of implementation will reveal the previously unseen viewpoints and agency of Global South communities and mid-level aid workers on the international system. A more granular understanding of the lived experience of international development, including the coercion, resistance and renegotiation that often attended development projects in the Global South, will also facilitate a re-evaluation of historical international development and the broader systems of global governance that emerged in the post-war period. To achieve these outcomes, DEVHIST will pioneer a multiscalar historical methodology that traces international development programmes through every stage of their lifecycle, and draw upon a previously neglected source base including Project Files and Global South-produced accounts. It will apply this approach to programmes and projects implemented by a range of development actors, including Western and Eastern bloc state development agencies, multilateral development banks, international organisations, and development NGOs, in Asia, Africa and Latin America.

Keywords: history of international development,global south,international organisations,multiscalar history