Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Cellulose scattering enhancers for replacement of Titania nanoparticles (CelluNANo)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: United Kingdom
Call: Call for proposals for ERC Proof of Concept Grant (ERC-2020-PoC, 2020)
Start date: 2020-11-01
End date: 2022-10-31
Duration (months): 24.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Nanomaterials, especially if bio-sourced, have huge promise in a wide range of applications of societal importance to replace inorganic and synthetic counterparts. This is particularly important in the pigment industry, which has long relied on the use of inorganic nanoparticles as scattering enhancers. Now there is a growing demand for natural and sustainable alternatives that avoid the growing concerns over potential long-term health impacts of inorganic materials such as Titanium dioxide (TiO2) nanoparticles. This proposal aims to harvest the design principles offered by natural nanomaterials to fabricate new highly scattering materials using only biopolymers. By exploiting the most abundant biopolymer on the planet, cellulose, and replicating highly scattering architectures observed in nature, this grant aims to scale up a newly developed generation of scattering enhancers that can completely replace the currently used TiO2 nanoparticles. The ability to control the scattering efficiency of cellulosic material will allow us to produce truly sustainable white enhancers that can find use in everyday application such as cosmetics, food, packaging as well as paints and coatings.

Keywords: cellulose,optical material,whitener,biopolymers,sustainability
Multi-Stimuli Responsive Molecular Systems and Materials (ResMoSys)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Israel,Switzerland,Sweden,Sweden,France,France,Netherlands,Netherlands,United States,Netherlands,Denmark,Denmark,Denmark,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 2646333.72
EU funding (EUR): 2646333.7199999997
Participants: 17
Project status: CLOSED

Nanotechnology has been identified as a key enabling technology of economic growth and the value of nanomaterials in the global market is forecast to grow to €2 trillion by 2015. In order to be a market leader in this area, it is imperative that Europe invest in research where the gap between knowledge creation and successful commercialisation is bridged, and in training the next generation of highly skilled researchers in nanotechnology. This ETN will increase innovation capacity and strengthen doctoral training in nanotechnology on a European level. The ETN will push research into applications at the cutting-edge of nanotechnology by uniting leading experts from both the academic and non-academic sectors under the theme “Multi-Stimuli Responsive Molecular Systems and Materials.” The objective of the research programme is to prepare new “smart” molecular systems and materials in a bottom-up approach from low molecular weight building blocks by exploiting dynamic covalent chemistry and supramolecular interactions. Close collaboration between the academic and industrial members in this ETN will ensure immediate commercialisation of any new technology or materials developed by the network. This ETN provides a highly structured and comprehensive training programme in nanotechnology, a subject not specifically taught in many European universities. Early-stage researchers will be recruited and trained so they are equipped with a balance of research-related and transferable skills to enhance their career perspectives in both the academic and non-academic sectors. Thus, the network will produce highly skilled, creative, innovative and entrepreneurial researchers who will contribute to European innovation capacity in nanotechnology.

Keywords: dynamic combinatorial chemistry
Clinical evaluation of carbons of controlled porosity as a new therapeutic for the treatment of liver cirrhosis and non-alcoholic fatty liver disease. (CARBALIVE)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Spain,Spain,Switzerland,France,United Kingdom,Portugal,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: New therapies for chronic non-communicable diseases (H2020-PHC-2014-two-stage, 2014)
Start date: 2015-05-01
End date: 2021-01-31
Duration (months): 69.0
Total project cost (EUR): 9579686.54
EU funding (EUR): 5913079.75
Participants: 19
Project status: SIGNED

Chronic liver disease affects about 29-million Europeans accounting for about 170,000 deaths at a cost of around €15.8bn. This chronic non-communicable disease is increasing at an alarming rate due to increasing European obesity, alcohol use and ageing. The three main causes of the disease; alcohol, fatty liver and viral hepatitis are amenable to prevention and treatment. Gut-derived endotoxins and bacterial translocation are central factors implicated in the pathogenesis of fatty liver disease and, the development and progression of cirrhosis. In cirrhosis, current state-of-the-art therapy to prevent recurrent complications of advanced cirrhosis is to use poorly absorbed antibiotics but long-term antibiotic therapy has problems associated with bacterial resistance, infection with resistant organisms and the cost. Treatment of fatty liver and modulation of bacterial translocation in early cirrhosis to prevent complications is an unmet need. Our academic-industrial consortium has developed a novel, patented, safe and cheap nanoporous carbon that modulates the effects of bacterial translocation in animal models of liver disease. Our feasibility studies demonstrate that this product advances the current state-of-the-art, is a TRL 4/5 and is now ready for validation through clinical trials. We propose to investigate the safety and efficacy of this novel nanoporous carbon in patients with fatty liver disease and cirrhosis. If successful, we will be able to confirm an innovative, cost-effective and novel strategy for the management of this chronic disease in a European population. Exploitation of the results of the CARBALIVE project will support the continued development of this carbon through additional private and public sector investment. The use of this innovative therapy is expected to reduce the economic burden of the disease in Europe, allow patients to achieve enhanced quality of life, improve survival, and allow many patients to return to economic productivity.

Keywords: nanoporous carbon,liver cirrhosis,nafld
Enhancing innovation management capacity of SMEs under H2020 programme in the Enterprise Europe Network Normandie (EEN Normandie h2020)

Framework: Horizon 2020 — EC Treaty
Action type: Specific Grant agreement
Countries involved: France
Call: EEN H2020 SGA2 2D BATCH (H2020-EEN-SGA2-2017-1, 2017)
Start date: 2017-03-01
End date: 2018-12-31
Duration (months): 22.0
Total project cost (EUR): 79075.0
EU funding (EUR): 79075.0
Participants: 2
Project status: CLOSED

On January 1st, 2016, the French regions experienced a territorial reform which led to the merger of several French regions. On the Normandie-Picardie consortium territory, the Upper and Lower Normandy regions are reunited to form the Normandie region and Picardie region is attached to the Nord de France region. In parallel, on January 1st, 2016, the CCI of Haute-Normandie and the CCI of Basse Normandie merged and became CCI Normandie. On July 1st, 2016, the two Norman regional agencies for innovation are grouped into a single structure named Agence de Développement pour la Normandie (AD Normandie). For the 2017-2018 period, CCI Picardie decided to harmonize the territorial map of the EEN consortium with the new French regions. Thereby, on January 1st, 2017, CCI Picardie will withdraw from the consortium Normandie-Picardie.The new Normandie consortium succeeds the Normandie-Picardie consortium. It fully pursues its activities to support innovation and internationalization. The new Norman consortium ensures the continuity of all EEN COSME and H2020 services, especially the action called “Enhancing the innovation management capacity of SMEs”. This specific action will be divided into two main Work packages. The first one called “Key Account Management” (KAM) will target the beneficiaries of the SME Instrument. The Key Account Managers will ensure that the beneficiaries receive the most appropriate services to underscore the successful and profitable exploitation of their innovation project. The second one called “enhancing SME innovation management capacity” (EIMC) will target SMEs with significant innovation activities and a high potential of internationalization. The consortium advisors will deliver a quality management assessment and support services to conduct innovation processes in a more effective way. They will be in charge of assessing innovation management capacity of the company and to develop an action plan with the support of an diagnostic tool.

Keywords: in this proposal,enterprise europe network normandie proposes two activities key account,management and enhancement of innovation management capacities
MAXIMISING SUNLIGHT RESOURCES FOR COST, ENERGY AND YIELD EFFICIENT GREENHOUSES (SUN4GREEN)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain,Israel
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2015, 2015)
Start date: 2015-06-01
End date: 2015-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

GHs are dominantly plastic foil covered structures and tunnels targeted to intensive and protected crop production. The maintenance of optimal temperatures and optimal light incidence is critical for high crop yields. In summer, GHs are typically white washed or shaded by nets or by screens, in order to avoid excess temperature in the GH. Standing out, this sunlight surplus can be turned into electricity by adding PV panels, which can supply electricity to the national grid and/or supply the required energy for a heating/cooling system for the optimal control of the GH micro-climate. However, previous attempts of dual harvesting, which have been performed mainly in Italy and Spain, used conventional PV panels or semi transparent PV panels that were positioned to receive maximum sunlight on the south facing roof of GHs and significantly shaded crops all year around, resulting in a significant a negative effect, not only with regards to high crop yields loss, up to 25% but also to negative effects on edibles and fruit size, hardness and colour, which reduce sell prices of affected crops. On the other hand, If PV panels would have been placed in other positioning then, PV harvesting would underperform and consequently PV yields would be reduced. SUN4GREEN new smart design directs light either into the greenhouse or to the PV panels depending on the season need. What makes SUN4GREEN different and revolutionary is that its performance is season dependant and is adapted to GH characteristics. Its design allows growers having real dual sun and crop harvesting targeted to obtain benefits from both sources, which is not possible with simple, direct PV technology implementation, not adaptable to seasonal agriculture requirements and where thus, agriculture was compromised to make room for PV electricity production. In addition, we achieve up to 75% CO2 savings by reducing dependence on fossil fuels.

Keywords: greenhouse,photovoltaic,crop yields,dual harvesting
REScoop Plus (REScoop Plus)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Market uptake of energy innovation
Action type: Coordination and support actions
Countries involved: Italy,Spain,Italy,Belgium,Greece,Belgium,France,Netherlands,Netherlands,Portugal,Denmark
Call: Consumer engagement for sustainable energy (H2020-EE-2015-3-MarketUptake, 2015)
Start date: 2016-03-01
End date: 2019-02-28
Duration (months): 36.0
Total project cost (EUR): 1498937.5
EU funding (EUR): 1498937.5
Participants: 12
Project status: CLOSED

REScoop Plus built on the knowledge and network of the REScoop 20-20-20 project. An interesting additional observation made in the project was that members of supplying REScoops change their behaviour reducing final energy consumption and investing money to produce RESenergy. The aim of the REScoop PLUS is therefore to get a better understanding and foster this behavioural change. It will identify and measure the best practices, share their knowledge, improve their activities in in their citizen’s engagement and energy efficiency actions and disseminate them to other supplying REScoops in Europe. The objective of REScoop PLUS is to make REScoops in Europe go beyond their activities of producing and supplying energy and take up energy savings for their members as a new pillar in their organisation. The largest supplying energy REScoops in Europe have recently taken up this task in several experimental projects, with different rates of success for different measures and geographies. The aim is now to go beyond the experimental phase and create a toolkit with a range of best practice products like communication tools, ICT tools for better measurements or new business models that support energy savings of consumers/members by changing the behaviour of consumers that are ready for market uptake by REScoops to implement into their organisation in order to reduce the CO2 footprint of their members.

Keywords: energy cooperatives,behaviour analisys
Networking, partnerships and tools to enhance in situ conservation of European plant genetic resources (Farmers Pride)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Coordination and support actions
Countries involved: Austria,Spain,Spain,Italy,Germany,Italy,Belgium,Greece,Türkiye,Sweden,Finland,Switzerland,Hungary,Netherlands,Netherlands,Denmark,Portugal,United Kingdom,United Kingdom
Call: New partnerships and tools to enhance European capacities for in-situ conservation (H2020-SFS-2017-1, 2017)
Start date: 2017-11-01
End date: 2021-07-31
Duration (months): 45.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 19
Project status: CLOSED

The overarching objective of Farmer’s Pride is to establish a network of stakeholders and conservation sites that effectively coordinates conservation actions to safeguard the wealth of Europe’s in situ plant genetic resources (PGR) and integrates the user community to maximize their sustainable use. Specifically, to address the challenge and scope of the SFS-04-2017 work programme, Farmer’s Pride will: a) build relationships between existing diverse PGR stakeholder networks, and where necessary create new partnerships to establish a unified network of stakeholders involved in PGR conservation and sustainable use; b) enhance existing knowledge of European landrace and crop wild relative genetic diversity and showcase how it can be effectively secured and managed; c) use social science and economic tools to establish the value of in situ PGR populations and individual traits, as well as a cost effective means of conserving them; d) use predictive characterization methods to identify valuable traits in in situ PGR populations, targeting those most vital for satisfying future agricultural and market needs; e) establish a mechanism to facilitate the flow of plant genetic material from in situ populations to the user community, both directly and via ex situ collections; f) develop and establish a durable governance and resourcing structure for the European network of in situ PGR conservation sites and stakeholders; g) promote public awareness of the value of PGR for agriculture and consumers; and h) design and implement a network of European sites and stakeholders that conserves the breadth of PGR diversity found in situ. Through these activities, Farmer’s Pride will result in significant strengthening of European capacities for the conservation, management and sustainable use of in situ PGR as a foundation for increased competitiveness in the farming and breeding sectors, and ultimately for long-term food and nutritional security in Europe.

Keywords: plant genetic resources,in situ conservation,on farm conservation,crop wild relative,landrace,site network,stakeholder network,farmer participation,multi actor approach,plant breeding
Anticipatory Human-Computer Interaction (ANTICIPATE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Germany
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-02-01
End date: 2024-01-31
Duration (months): 60.0
Total project cost (EUR): 1499625.0
EU funding (EUR): 1499625.0
Participants: 1
Project status: SIGNED

Even after three decades of research on human-computer interaction (HCI), current general-purpose user interfaces (UI) still lack the ability to attribute mental states to their users, i.e. they fail to understand users' intentions and needs and to anticipate their actions. This drastically restricts their interactive capabilities. ANTICIPATE aims to establish the scientific foundations for a new generation of user interfaces that pro-actively adapt to users' future input actions by monitoring their attention and predicting their interaction intentions - thereby significantly improving the naturalness, efficiency, and user experience of the interactions. Realising this vision of anticipatory human-computer interaction requires groundbreaking advances in everyday sensing of user attention from eye and brain activity. We will further pioneer methods to predict entangled user intentions and forecast interactive behaviour with fine temporal granularity during interactions in everyday stationary and mobile settings. Finally, we will develop fundamental interaction paradigms that enable anticipatory UIs to pro-actively adapt to users' attention and intentions in a mindful way. The new capabilities will be demonstrated in four challenging cases: 1) mobile information retrieval, 2) intelligent notification management, 3) Autism diagnosis and monitoring, and 4) computer-based training. Anticipatory human-computer interaction offers a strong complement to existing UI paradigms that only react to user input post-hoc. If successful, ANTICIPATE will deliver the first important building blocks for implementing Theory of Mind in general-purpose UIs. As such, the project has the potential to drastically improve the billions of interactions we perform with computers every day, to trigger a wide range of follow-up research in HCI as well as adjacent areas within and outside computer science, and to act as a key technical enabler for new applications, e.g. in healthcare and education.
ASTRocyte Adrenoceptors: Light on Intracellular Signaling (ASTRALIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,United States
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-07-30
End date: 2023-08-29
Duration (months): 36.0
Total project cost (EUR): 264669.12
EU funding (EUR): 264669.12
Participants: 2
Project status: SIGNED

ASTRALIS proposes all-optical strategies to shed light on holes in our understanding of how intracellular signaling complexity, downstream of specific G protein-coupled receptors (GPCRs), is generated in the brain. We focus on the understudied cells of the brain, astrocytes, which are highly interconnected but electrically silent, and signal through GPCRs and second messengers in response to norepinephrine (NE). We use them as models to study whether intracellular signaling in vivo is governed extrinsically, by noradrenergic afferent fibers releasing neuromodulators in defined spatiotemporal patterns –and therefore by receptor-specific activation dynamics– or rather intrinsically, by compartmentalization of cellular components, resulting in spatiotemporally different signaling outputs. During the outgoing phase, I will use advanced optical approaches to: (1) measure the spatiotemporal dimension of NE release in vivo, and (2) characterize the cellular and subcellular heterogeneity of astrocytic signals in response to NE in vitro and their relevance to the circuit, by simultaneously monitoring astrocytic and neuronal activity. During the incoming phase, I will (3) combine knowledge generated within the outgoing phase about in vivo noradrenergic signaling with the optical technologies developed by the host lab, in order to dissect the contribution of receptor dynamics to the spatiotemporally defined signaling of adrenoceptors. Significance: Current strategies to study intracellular signaling downstream of GPCRs widely neglect the spatiotemporal component of the inputs to which receptors are exposed naturally. Clarifying these aspects of receptor function would radically change the way we probe and study these proteins. In addition, elucidating the largely disregarded contribution of astrocytes in noradrenergic signaling at the cellular and network level will help understand the pathophysiology of related disorders and conceive better therapeutic strategies.

Keywords: adrenergic,astrocyte,intracellular signaling,g protein coupled receptor,fret sensor,uncaging,two photon imaging,nanosensor