Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Advancing Clinical Care and Equity through Scalable Solutions in Alzheimer’s Disease diagnosis and treatment (ACCESS AD)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Innovative Health Initiative
Action type: Research and Innovation actions
Partnership: IHI (JU-JTI)
Countries involved: Netherlands,Germany,Norway,Greece,Sweden,Luxembourg,Spain,Finland,Switzerland,United Kingdom,Czechia,India,United States
Call: Boosting innovation through better integration of fragmented health R&I efforts (HORIZON-JU-IHI-2025-09-single-stage, 2025)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 37592288.0
EU funding (EUR): 20190282.35
Participants: 36
Project status: SIGNED

Alzheimer’s disease (AD) is a growing public health challenge in Europe’s ageing population. While Disease Modifying Therapies (DMTs) bring new therapeutic potential, fragmented care pathways, unequal diagnostic access, and healthcare limitations threaten their effectiveness and scalability. The Access AD Project is a collaborative initiative that exemplifies the public-private partnership model, bringing together government agencies and private sector organizations to addresses this unmet need by translating advanced diagnostics and monitoring approaches—such as blood-based and imaging biomarkers, digital and AI tools—into coordinated, equitable, and scalable care across real-world clinical settings in Europe. The project aims to ensure that every individual with AD can access timely, personalized, and cost-effective care, regardless of geography or socioeconomic status. ACCESS-AD builds on local, national, and EU-level efforts to create an integrated, pan-European framework for optimized AD care. The project will achieve: 1) establish robust coordination and governance to ensure efficient delivery and stakeholder alignment; 2) connect and expand fragmented clinical and research data through a shared platform, linking registries and initiatives across Europe; 3) reduce diagnostic access barriers by improving standardized imaging, blood-based, and digital biomarkers for clinical use; 4) develop AI-driven tools to support personalized treatment decisions; 5) generate harmonized real-world evidence on DMTs and emerging therapies; 6) assess health-economic, regulatory, and patient-reported impacts; 7) engage patients, professionals, and policymakers to ensure adoption and sustainability. Aligned with IHI Call 9.2, ACCESS-AD unites and engages diverse healthcare stakeholders and integrates needs and perspectives of individuals affected by dementia to deliver inclusive, connected, and personalized care centered around the AD patient. By translating innovation into real-world practice, the project will reduce inequalities, support health policy, and improve outcomes for AD patients across Europe.

Keywords: alzheimer s disease,blood based biomarkers,imaging biomarkers,digital health,artificial intelligence,personalized care,real world evidence,disease modifying therapies,treatment monitoring
Woamy - A way out of plastic foams (WOAMY)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Finland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

WOAMY – A way out of plastic foams World is drowning in plastic waste. Only fraction of plastic waste generated by the society goes through appropriate waste management. Majority of plastic waste ends up to nature. For example, of all the plastic waste found in oceans approximately 90 % are various plastic foams. Instead of biodegrading, plastics decompose to microplastics in the nature from which they circulate through the ecosystem. Nowadays, remarkable amounts of microplastics are found even from digestive systems of human living in modern societies. Woamy offers a solution to plastic waste problem by introducing a novel bio-based solid foam product FOAMWood® that can replace plastic foams in numerous of applications. The production technology is based on extensive scientific research results. The key features of the process are protected with a patent. The patent has been granted in Finland and the application is bending in ten other regions. Woamy has spent the past one and a half years to research an optimal way to scale up the technology towards commercial operation. Presently, we operate the technology on a semi-continuous manner in a relevant environment. In addition, Woamy has demonstrated the market traction through multiple PoC project in packaging sector applications. The global packaging foam markets exceeding annual size of 17B$ offer a low barrier market entry point for Woamy. In later stages, Woamy plans to revolutionize other foam markets with size of 142B$ involving construction sector, laminated boards, mattresses etc. With the EIC Accelerator project, we expect to pilot the continuous production of FOAMWood® in an industrial environment. A successful project will enable securing investment to build a first commercial scale factory. The project can accommodate rapid growth globally reaching to operating dozen factories in multiple continents and reaching revenue of more than 50M€ in five years after the project.
Next-Generation Quantum Key Distribution for a Secure Digital Future (NEXUS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

In an era of unprecedented digital threats, Europe faces a critical cybersecurity crisis. The coming of quantum computers threatens to render current cryptography methods obsolete, potentially exposing sensitive government, financial, & personal data to malicious actors. This is compounded by the “harvest now, decrypt later” strategy, where adversaries stockpile encrypted data for future decryption, jeopardizing long-term data security. Q*Bird addresses this crisis with our groundbreaking Measurement Device Independent Quantum Key Distribution (MDI-QKD) technology. Unlike traditional QKD systems, our solution offers unparalleled security, scalability, & cost-effectiveness. Our multi-point-to-multi-point architecture enables easy network expansion, dramatically reducing per-user costs while maintaining quantum-safe security. This innovation not only safeguards against current and future quantum threats but also lays the foundation for the emerging Quantum Internet. A European deep-tech startup, Q*Bird is uniquely positioned to contribute to the EU's technological sovereignty in this critical domain. Our technology aligns perfectly with key EU initiatives such as the European Quantum Communication Infrastructure (EuroQCI) and the Cybersecurity Strategy for the Digital Decade. However, the high-risk nature of quantum technology development, coupled with long commercialization timelines, creates significant challenges in securing sufficient private investment. EIC Accelerator support is crucial to bridge the gap between our current prototype and full commercialization. This support would not only accelerate our technology development but also catalyze additional private investment, enabling Europe to lead in the quantum communication revolution. With EIC backing, Q*Bird can transform the secure communications landscape, ensuring Europe's digital resilience in the quantum age.

Keywords: quantum cryptography quantum key distribution measurement device independent qkd cybersecurity quantum communication quantum networks quantum internet
UCon – A novel, minimally invasive and cost-efficient neuromodulation therapy for incontinence (UCon2024)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499000.0
EU funding (EUR): 2499000.0
Participants: 1
Project status: SIGNED

We've developed a breakthrough class III medical device to treat Overactive Bladder and faecal incontinence, targeting 42 million patients in the EU alone. Our method involves electrical stimulation targeting the Dorsal Genital Nerve (DGN) to prevent involuntary urine or faeces leakage. Using patented electrode technology, our innovative approach precisely stimulates the DGN. The UCon device, designed with the stimulator placed externally and only the electrode penetrating the skin, significantly reduces costs compared to full implants. It's minimally invasive, allowing for electrode insertion within minutes with low patient risk. UCon offers a robust alternative to the billion-euro market of established implanted neurostimulators, which are costly and invasive, serving only a limited patient segment. Additionally, UCon provides an alternative to pharmaceuticals and Botox treatments.

Keywords: urinary incontinence,faecal incontinence,overactive bladder,neuromodulation,neurostimulation
Dramatic hardware and energy savings in demanding server applications with a novel approach for storage memory optimization (SuperFlash)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 48.0
Total project cost (EUR): 2499900.0
EU funding (EUR): 2499900.0
Participants: 1
Project status: SIGNED

Computer architecture faces a critical challenge with the memory systems, so-called Memory Wall. It remains the main bottleneck for data-centric and time-critical applications (e.g. AI modeling, big data analytics, video streaming). Many of those applications operate on large datasets kept in storage memory. Yet, storage has the biggest bandwidth limitations and the longest access time of all memory types. Storage bottlenecks generate challenges for the end-users. Due to Storage Challenge, Data Center providers face an urgent business need for net memory expansion by optimizing the use of their storage resources. Energy Challenge causes soaring Total Cost of Ownership (ToC), a key metric for long-term profitability of Data Centers. Cost of Compute Challenge is reflected in the increasing computational needs of ever-growing AI models. In enterprise storage memory, that implies a need for methods unlocking a more efficient use of the existing resources to store the datasets. We are addressing these challenges with SuperFlash, a groundbreaking technology for storage architecture optimization. SuperFlash offers a comprehensive working principle that, for the first time ever, merges memory compression, compaction and management. That revolutionizes the energy efficiency and performance of storage systems, bringing up to 50% more FLOPS/Watt and up to 4x higher memory capacity and bandwidth while operating with negligible latency. SuperFlash maximizes the use of enterprise storage systems and decreases the ToC, putting up to 70% of the unused memory to instant work. It can be easily integrated as an IP core on any relevant System-on-a-Chip. This boosts the performance, brings low power consumption and no extra hardware costs. In this project, we will take SuperFlash through the entire IP Product Development Process, making it ready for chip tape-out. With the help of two Validation Partners, we will validate SuperFlash in silicon, making it qualified for mass production.

Keywords: memory system architecture,computer architecture,embedded systems,memory optimization,flash storage memory,ip design,system on a chip,high performance computing,cloud storage,data center
DRIVIN' CAR: Developing robust in vivo nanomedicine-based chimeric antigen receptor technology (DRIVIN CAR)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands,Belgium,Germany
Call: EIC Pathfinder Open (HORIZON-EIC-2025-PATHFINDEROPEN, 2025)
Start date: 2026-03-01
End date: 2030-02-28
Duration (months): 48.0
Total project cost (EUR): 3000347.5
EU funding (EUR): 3000346.0
Participants: 6
Project status: SIGNED

DRIVIN’ CAR aims to transform immunotherapy by developing a scalable, cost-effective platform for in vivo generation of chimeric antigen receptor (CAR) immune cells. Using proprietary apolipoprotein nanoparticle (aNP) platform technology, DRIVIN’ CAR pursues robust CAR monocyte/macrophage (CAR M) and CAR T cell therapy. Owing to their biocompatibility and natural tropism for myeloid cells, aNPs are excellently suited for in vivo CAR M therapy. For efficient in vivo T cell targeting, aNPs can be modularly surface-functionalized with apolipoprotein fusion proteins. The Program’s aNP platform technology addresses key limitations of current CAR therapies that prevent widespread implementation. It simultaneously tackles high treatment costs, complex ex vivo manufacturing procedures, and poor performance in solid tumors of conventional CAR cell therapy. The aNP platform also overcomes challenges associated with emerging in vivo approaches, such as limited specificity and safety risks. By combining advanced bioengineering, high throughput manufacturing, library screening approaches and in vivo validation, DRIVIN’CAR brings together world-leading experts to deliver a unique and versatile platform for in vivo CAR therapies with real clinical impact. This Program’s successful completion will advance the aNP platform to TRL 4. Besides enabling in vivo CAR immune cell therapy for cancer treatment, the aNP platform has significant translational potential and pertinency for applications in non-malignant diseases such as autoimmune disorders and cardiovascular disease.

Keywords: nanoparticles,in vivo car cell therapy,car t,car m
Mint the Gap: Coinage, Land Market and the Economic Rise of Medieval Italy (RaESETfides)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1251212.5
EU funding (EUR): 1251212.0
Participants: 1
Project status: SIGNED

The functioning of medieval economies has been widely debated and often misunderstood. RaESETfides will tackle the problem by looking at one of the most obscure conundrums in the history of the central Middle Ages: how could a group of small polities in the upper half of the Italian peninsula become the economic powerhouse of Latin Europe during the 12th and 13th centuries – a characteristic it would maintain, in fact, until the early modern era. The project will sit within a rapidly-developing field in the economic history of the Middle Ages. In The Donkey and the Boat: Reinterpreting the Mediterranean Economy, 950-1180 (OUP, 2023), Chris Wickham has shown that, during the 11th and 12th centuries, the most advanced economy of the Mediterranean basin was Egypt, but he also hypothesised that from the last quarter of the 12th century some Italian towns managed to take over much of the maritime commerce and shift it to northern Europe. How exactly this happened, however, remains to an extent a mystery, which is all the more fascinating when one considers that north-central Italy was agriculturally poor, politically fragmented and ravaged by constant warfare – the unlikely candidate to widespread economic prosperity. RaESETfides aspires to make a major contribution by taking into account an ill-studied area of research – that is, the institutional changes of north-central Italian polities and the economic impact of such changes. It will do so through the large-scale investigation of the written evidence preserved in the archives of seven cities, namely Genoa, Milan, Pisa, Rome, Siena, Venice and Verona, which will serve as a basis to pursue four innovative objectives – consisting in the study of exchange rates, of the evolution of land prices, of the debasement of the currency and of the transformation of credit markets. The project will take place at the University of Bologna, which has a vibrant historical culture but lacks, at present, a focus on medieval economy.

Keywords: numismatics statistics economic anthropology environmental history
Disordered metasurfaces with ultimate information capacity for near-infrared spectroscopy (Metaspectrometer)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France,United States,Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-05-01
End date: 2028-10-31
Duration (months): 42.0
Total project cost (EUR): 353380.32
EU funding (EUR): 353380.32
Participants: 4
Project status: SIGNED

Speckle patterns are distinct features of disordered materials. While often regarded as mere noise, the intricate and responsive speckle patterns to minor fluctuations in external factors render them an ideal candidate for applications in hyperspectral imaging and sensing. The MetaSpectrometer harnesses the high information capacity of the speckle pattern of resonant disordered metasurfaces for compact, machine learning-assisted, non-invasive, and efficient near-infrared spectroscopy. An ultra-compact footprint, portability, cost-efficiency, minimal losses, machine-learning assisted recognition, angle-insensitivity, suppressed specular scatterance, significant memory effect, and ability to accommodate low coherence fields are the main features that cannot be currently obtained with any technology proposed so far and would represent a huge step forward in the state of the art. MetaSpectrometer brings together the complementary expertise of the postdoctoral researcher (PR) in metasurface engineering; the incoming host (CNRS-C2N, France) in silicon photonics, optoelectronics and nanofabrication; the associated the outgoing host (MIT, USA) in spectroscopy and machine learning, the secondment host (Rice, USA) in lensless imaging and the industrial partner (ZEISS, Germany) in spectroscopy and market analysis. The project allows PR to acquire expertise in silicon photonics technology's design, fabrication, characterization, and commercialization while giving back his expertise in metasurface design. The developed NIR spectrometers will find direct potential applications in wearable health monitoring systems, food screening, agriculture, and environmental screening that a remarkable global market size. The distribution of the work packages with distinct and clearly defined milestones and deliverables makes sure that the progress of the project will be monitored and matched with the work plan.

Keywords: metasurface,spectrometer,disorder,metamaterial,integrated photonics,silicon photonics
Dynamic Automatic Region Tracking (DART) (DART)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2025-POC, 2025)
Start date: 2025-11-01
End date: 2027-04-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Capturing nature’s most fleeting moments, such as a lemur leaping, a peregrine falcon striking, or dragonflies dueling over water, has always relied on a mix of skill and luck. It also demands extensive setup and long waits in harsh environments. With Dynamic Automatic Region Tracking (DART), these moments become routine and much easier to capture. DART revolutionizes nature cinematography with bioinspired algorithms and cutting-edge hardware. Using motorized mirrors to steer a camera’s view, it enables ultra-fast, high-resolution tracking of unpredictable subjects. The system integrates two cameras: a wide-angle search camera to detect action and a telephoto homing camera to capture it in stunning detail. Its bioinspired vision algorithm and controller enable low-latency, data-efficient, and energy-efficient continuous operation. This project will refine DART’s tracking algorithms and hardware controls to create a modular, plug-and-play solution for applications in agri-tech, environmental monitoring, industrial automation, entertainment, and wildlife documentary production. Building on our strong academic expertise in robotics and biomechanics, DART is now advancing toward real-world demonstrations with early partners. By capturing what once seemed unfilmable, DART opens new frontiers in motion analysis and visual storytelling.

Keywords: visual tracking,bioinspired vision,nature documentary,motion capture,unmanned aerial system research