Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Strengthening the research and innovation capacities of the Latvian Institute of Organic Synthesis, the leading Baltic regional centre for drug discovery (INNOVABALT)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Latvia
Call:  (FP7-REGPOT-2012-2013-1, 2012)
Start date: 2013-09-01
End date: 2017-02-28
Duration (months): 42.0
Total project cost (EUR): 5262038.0
EU funding (EUR): 4707491.0
Participants: 1
Project status: CLOSED

The general objectives of the InnovaBalt project are to improve multidisciplinary research capacities and strengthen the management of intellectual property and human resources for innovative drug discovery at the Latvian Institute of Organic Synthesis (LIOS). LIOS is the leading regional research centre for drug discovery, which consists of organic synthesis, medicinal chemistry and the pharmaceutical development of compounds designed for the treatment of cancer, cardiovascular diseases and CNS disorders. LIOS has a clear vision of its mission, which is to develop sustained research activities in the domain of innovative medicine. The following objectives will be implemented: 1. Long-lasting scientific collaboration and strategic partnerships between LIOS and 50 outstanding research institutions will be established and sustained to increase the visibility of LIOS in the European Research Area (ERA); 2. The management of intellectual property will be improved and innovation will be increased by collaborating with and attracting 14 external professionals; 3. The research infrastructure and qualification of human resources at LIOS will be upgraded in the fields of modern process chemistry, green chemistry, biophysical chemistry, in silico drug discovery, advanced forms for drug delivery and research and innovation management to promote the capacity for high-level research on innovative drug development; 4. Synergy between research on innovative drug development and end-users will be ensured to meet the socio-economic needs of the Baltic region. The implementation of the aforementioned objectives will reinforce the strategic development of LIOS, improve the scientific outcomes and promote the long-term impact of the LIOS research through its wholesome integration into the ERA.

Keywords: medicinal chemistry,drug discovery,organic synthesis,process chemistry,molecular modelling
Centre of Excellence for Research on Environment, Health and Aging (CEREHA)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Israel
Call:  (FP7-REGPOT-2012-2013-1, 2012)
Start date: 2012-10-01
End date: 2016-03-31
Duration (months): 42.0
Total project cost (EUR): 5428570.8
EU funding (EUR): 4467226.0
Participants: 1
Project status: CLOSED

Objectives: CEREHA - Centre of Excellence for Research on Environment, Health and Aging is structured to be an inter- and multidisciplinary centre led by MIGAL. This project is the most important research initiative of the Galilee region in Northern Israel. The main objective of CEREHA is to become internationally known research institute, which is capable of initiating and performing excellent interrelated studies in environment, health and aging. Activities: CEREHA will study the aging phenomena employing biological, medical, environmental, epidemiological and social perspectives. Such research requires the creation of a unifying umbrella that will bridge across the inherent fragmentation in science and aggregate the research efforts, especially in human potential across the whole Mediterranean region. The project is encompasses of 6 research institutions, including public and private sectors from Denmark, Germany, Italy, the Netherlands, Norway and USA. The work-plan is divided into 8 WPs, including Management and Ex Post Evaluation. The other WPs are constructed to pave the way to excellence and include secondments from and to partners, upgrade of existing experimental and research facilities, cycles of seminars and international contacts with other research and business organisations, and finally activities geared towards a regional dimension, in view of sparking a competitiveness dynamic in the Galilee. The dissemination activities are also directed to raise complementary funds by the Israeli government. Expected impact CEREHA will create a high quality and high visibility Centre, which will encompass research on health and environment in relation to aging. This Centre, will strive to get input from several other Centres of Excellence in Europe and in the US. This knowledge exchange will be formulated and transformed into meetings, symposia, and workshops that undoubtedly will have a significant and lasting impact on the aging population in the Galilee and beyond. These activities are inherent part of CEREHA's long-term strategy to raise the research and innovation profile of the Galilee - Israel’s peripheral region.

Keywords: health,aging,environmental effects,biotechnology,innovation,smes
Research and Innovation Capacity Strengthening of ISSP-BAS in Multifunctional Nanostructures (INERA)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Bulgaria
Call:  (FP7-REGPOT-2012-2013-1, 2012)
Start date: 2013-10-01
End date: 2017-03-31
Duration (months): 42.0
Total project cost (EUR): 4541368.8
EU funding (EUR): 4053611.0
Participants: 1
Project status: CLOSED

The Institute of Solid State Physics, part of the Bulgarian Academy of Sciences is the leading Bulgarian Research Institute in the field of solid matter research and its applications into multifunctional nanostructures.The INERA is an important mean for ISSP to rapidly increase its human and technological capacities, to reinforce its local networks and to deepen its partnerships on a European scale. It will mainly consist in an upgrade of equipment, scientific mobility trainings in leаding EU research centres, life-long trainings, partnership deepening and dissemination activities. INERA aims at preparing ISSP to become a national reference and reliable player on multifunctional planar nanostructures innovation niche employing available research capabilities and seeking EU soundness and visibility. The main expected project outcome for ISSP is to provide a new interdisciplinary view, to establish new links for common research and to encourage future synergies on national and international levels. The project will strengthen the capacity of business exploitation of research results and cooperation with industry and will build a long-term collaboration with research organizations and enterprises from EU. The project will have an important innovation impact as core research activities at ISSP are streamlined towards development of a Tunable Tool NanoMembrane: durable, high permeability, high thermal budget, tunable, scalable and Mass Production Capable Nanomembrane. This is expected to bring a new step in membrane technology development, triggering an avalanche of new products and processes in a wide range of applications including all known membrane industry aspects (separation by organic solvents, global water challenge like wastewater / desalination, fuel cells applications, and the life-health industries) with significant improvement of their energy effectiveness and environment ”shadow print”. INERA is supported by 8 leading EU research and 4 industry partners.

Keywords: multifunctional nanostructures research and innovation capacity strenthening
Unlocking the research potential of 3Bs Group, University of Minho, in Nanomedicine field to strengthen its competitive position at the European level (POLARIS)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Portugal
Call:  (FP7-REGPOT-2012-2013-1, 2012)
Start date: 2012-10-01
End date: 2015-09-30
Duration (months): 36.0
Total project cost (EUR): 3128788.91
EU funding (EUR): 2811238.0
Participants: 1
Project status: CLOSED

3Bs is situated in one of the most industrialised regions of Northern Portugal (PT11) where the economy is strongly based on traditional, low-tech and small family businesses. Withstanding these traditions, the group has been a lighthouse and an example on the exploitation of the regional research potential within the biomedical area. Based on interdisciplinary research where collaboration and cooperation are hallmarks of its culture, 3Bs is worldly recognised for its excellence and innovative approaches in the field of macro and microscale processing of biomaterials. The project POLARIS aims to strengthen this position of 3Bs by boosting the group activity in the field of Nanomedicine. An action plan that involve upgrading the group infrastructure with state of the art equipments for processing and characterisation of biomaterials at nanoscale as well as recruiting experienced researchers and technical staff in this field has been created and will be attained by the close cooperation with 4 leading European institutions: Chalmers University of Technology, Max Planck Institute for Intelligent Systems, University College Dublin and University of Strathclyde Glasgow. Transfer of know-how and experience between the partners will be enhanced by several events targeting scientific community but also the general public. A local SME – StemMatters is also part of the partnership since the 3Bs aims to become dynamic “innovation engine”, facilitating and accelerating the transfer of innovative technology from basic research to industry. Thus, POLARIS seeks for actual implementation of the obtained results that can be a vital “bridge” to growth, competitiveness, sustainability and employment in PT11.

Keywords: nanomedicine,nanotechnology,nanoparticles,nanostructured biomaterials,biosensors,bioarrays,microfluidics,self-assembling,layer-by-layer,lithography
Exchange of Excellence in Ubiquitous Computing Technologies to Address Healthcare Challenges (UBIHEALTH)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland,Denmark,United Kingdom,Spain,Türkiye,Italy
Call:  (FP7-PEOPLE-2012-IRSES, 2012)
Start date: 2012-09-01
End date: 2016-08-31
Duration (months): 48.0
Total project cost (EUR): 814800.0
EU funding (EUR): 814800.0
Participants: 7
Project status: CLOSED

Pervasive Healthcare is focused on working out how to cope with the next generation challenges in healthcare. Addressing these challenges will require expertise and knowledge exchange with countries beyond European borders as well as training of the next generation of researchers in order to gain the expertise necessary to be able to address the upcoming challenges. Moreover, research on Pervasive Healthcare has been conducted in several areas, ranging from assisting independent living at home, supporting hospital staff, promotion healthy habits, or providing care to for people with special needs. Each of the members of the consortium has worked in one or more of these areas and they will bring this expertise to the Consortium in terms of multi-disciplinary, methodological and technical approaches. The UBI-HEALTH program will create a stimulating research exchange foundation that will equip students from different continents with expertise in Pervasive Healthcare. The knowledge of requirements and available technologies for healthcare will be shared and become complementary between students, researchers and host institutions from Europe and the associated third countries including Mexico, Chile, China and USA (this last not funded by EU). This will allow students to put this knowledge in use in their own context, improving healthcare provisioning and impacting on both preventative medicine and alternative means of treatment. In summary, the main focus of the exchange program is in one hand to consolidate the Pervasive Health domain by interaction of Experienced Researchers in identification of challenges, setting of roadmaps and production of relevant didactic materials such as a course syllabus and textbook in the topic and to enable new generation of researchers to adapt novel technologies in different healthcare contexts and establish a network of knowledge dissemination between Europe and third countries.

Keywords: g314 medical engineering and technology,g105 human computer interaction and interface,g106 informatics and information systems,g204 systems engineering - sensorics - actorics - automation
AFFORDABLE SOLUTIONS FOR ASYMMETRIC REDUCTIONS OF INDUSTRIALLY RELEVANT SUBSTRATES (REDUCTO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy,Netherlands
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2016-09-30
Duration (months): 48.0
Total project cost (EUR): 487774.06
EU funding (EUR): 487774.06
Participants: 2
Project status: CLOSED

A number of methods exist for the production of enantiopure pharma intermediates. Among them, classical resolution by crystallization is the least efficient and most used one, while asymmetric catalysis, arguably the most efficient, is much less used. This paradox is due to a number of factors, such as: 1. High cost of the catalyst. 2. Lack of scope. 3. Time-to-market pressure. In this project we will investigate solutions to problems 1 and 2. We will develop new chiral catalysts for asymmetric double bond reduction that contain first-row base metals (e.g. Fe, Cu, Co, Ni). These metals are remarkably cheaper than their second and third-row noble metal counterparts (e.g. Ru, Rh, Ir, Pd, Pt). The chiral ligands should form strong bonds with these base metals in order to prevent the disabling metathesis of the complexes. In these complexes, we will also explore the use of “non-innocent” ligands which can participate in the transfer of electrons. The chiral ligands should be ideally produced in a few steps at low cost. According to a combinatorial approach, we will use libraries of ligands and of metal sources, so that the best hit can be rapidly identified. The second problem we want to address is the enantioselective reduction of pyridines, that so far have defied attempts at their asymmetric reduction to 2- or 3-substituted piperidines, which are important pharma intermediates. Disturbing the aromaticity of the pyridines via quaternization, or via binding to a metal surface or via eta6-binding to another metal complex will activate them for asymmetric reduction via catalytic hydrogenation or transfer hydrogenation. Our aim is to train two PhD researchers aware of the importance of sustainability issues (use of readily available metals, study of life cycle analysis assessment, carbon footprint evaluation) as well as expert in the use and combination of different catalytic methodologies as important tools for the responsible production of commodity and fine chemicals.

Keywords: c110 combinatorial chemistry,c111 method development in chemistry,c112 catalysis,c114 chemical reactions,c136 homogeneous and heterogeneous catalysis,c141 organic chemistry
Expanding Capability in Heterocyclic Organic Synthesis (ECHONET)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Spain,Germany,Italy,Spain,Germany,Netherlands,France
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 2881334.06
EU funding (EUR): 2881334.06
Participants: 8
Project status: CLOSED

ECHONET is an Initial Training Network (ITN) comprising 8 full network participants from 6 countries, spanning 6 academic institutions and two private sector organisations, the latter representing SME and Global fine chemicals companies. The network is also supported by 2 associated partners from the private sector. Taken together, the consortium will offer research training and generic skills development by embarking on state-of-the-art chemical synthesis problems and by employing new approaches in catalysis, computational chemistry, bioactive molecule design and high throughput synthesis. As a whole, ECHONET offers tremendous opportunities for research training in an international interdisciplinary environment. It is anticipated that this network will make a significant contribution to the expertise already present in Europe, and will continue to play an important role in the progress of European fine chemical industries and related fields. ECHONET will be supported by 11 early stage researchers and 2 experienced researchers and their research training will be supplemented by formal courses and industrial experience, therefore offering valuable exposure to commercial environments.

Keywords: c141 organic chemistry,c111 method development in chemistry,c112 catalysis,c134 biological chemistry
Multi-layer biopolymer films demonstrating selective gas barrier and functional properties suitable for high performance food packaging, derived from integrated bio-refining of sustainable biomass (BREW-PACK)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: United Kingdom,United Kingdom,United Kingdom,Germany,France,Belgium,United Kingdom,Netherlands,Estonia,United Kingdom
Call:  (FP7-SME-2008-1, 2008)
Start date: 2009-03-01
End date: 2011-08-31
Duration (months): 30.0
Total project cost (EUR): 1396086.0
EU funding (EUR): 1082991.0
Participants: 10
Project status: CLOSED

Conventional biorefineries target production of a single product stream utilising a dedicated crop based feedstock. Such processes offer limited commercial viability, generate significant waste streams and raise ethical and sustainability concerns with regards to the feedstocks used (competition with food crops & genetic modification to improve yield). Paralleling conventional petroleum refineries, integrated biorefining overcomes these limitations through utilisation of the wider biomass components to deriving multiple bulk and high value product streams (zero waste processes), thereby achieving commercial competitiveness in line with conventional refineries and enabling a transition from dedicated non-food crops to low cost, readily available and sustainable biomass. The Phytatec Technology Platform is built on this concept, combining environmentally benign critical fluid processes with the selectivity and efficiency of enzyme transformations. The BREW-PACK project will apply and further develop the existing Phytatec platform for the integrated biorefining of brewers spent grain ‘BSG’ (a readily available and low cost biomass feedstock), building on two core areas of innovation: - Application and further development of existing critical fluid processes for the sequential hydrolysis and fractionation of BSG to lipophilic, proteinaceous and polar (carbohydrate rich) primary material fractions - New know-how, strategies and technological development for the separation and knowledge based transformation of BSG proteins, enabling development of multi-layer biopolymer films demonstrating enhanced performance and functionality suitable for innovative high value packaging applications The project will conclude with a desk based feasibility study for design of a pilot and subsequent large scale plant, targeting establishment of supply chains worth over €72 million, generating ~450 new jobs and providing potential benefit to over 9000 wider SMEs.

Keywords: supercritical fluids hydrolysis enzyme catalysis bio-transformation surface modification structure property modelling
Light, easy to Cut and moisture proof façade Wallboard (CUTEWALL)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: France,Norway,Poland,Spain,Spain,Portugal
Call:  (FP7-SME-2008-1, 2008)
Start date: 2009-06-01
End date: 2011-05-31
Duration (months): 24.0
Total project cost (EUR): 1460795.0
EU funding (EUR): 1128168.0
Participants: 8
Project status: CLOSED

The construction sector employs directly 11.8 million people and is EU's largest industrial employer accounting for 7% of total employment in EU. About 910 billion Euro was invested in construction in 2003, representing 10% of the GDP. The construction sector is characterised by a large number of small enterprises, and relatively few large ones, with most enterprises serving a relatively small geographical market. When constructing blocks of flats the framework consist of a concrete skeleton making up the floors, ceilings, and transversal interior walls of the building. It is important to cover the facades as soon as possible so the building can dry properly and protect the interior from rain. Façade covers are traditionally temporary structures such as e.g. plastic covers supported by light wood or steel beams or permanent structures of wooden beams and gypsum. The temporary structures create a considerable amount of waste whilst the plaster and wood beams soak water that may give grounds for fungus and mould. Our idea is to develop a custom size, prefabricated façade wallboard to form part of the permanent construction based on water repellent closed cell polyurethane foam and construction waste as reinforcement. The wallboard will be up to 3 by 7.5 meter so no joints will be needed and light enough to be easily mounted using a lift and no scaffolds. The polyurethane foam has good insulation capabilities and combined with construction waste granulates as well as a geodesic net for reinforcement will provide the sufficient mechanical strength. Using waste as filler helps the construction industry to reduce the waste that normally would go to landfill. The product must be easy cut on the site to facilitate door and window assembly that often change from initial plans. The façade of each flat is typically 7.2 by 2.5 meter front and back. Assuming a retail price for our wallboard of €30 per m2 we get a European market value of €1.4 Bn and a global value of €3.2 Bn.

Keywords: polyurethane,rim,mould,fungus