Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Upscaling Mixing and Reactive Transport through Random Granular Media (MixUp)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2024-11-30
Duration (months): 27.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 2
Project status: CLOSED

Modeling reactive transport of solutes in aquifers and other porous formations is a field with key applications for a wide range of problems in contaminant transport, soil remediation, subsurface CO2 sequestration and geothermal energy. The wide range of scales at which fluid flows are governed by physical heterogeneities in porous media is a major obstacle in developing practical and accurate reactive transport models. The local mixing process governs (and may limit) the ability of reactants that are at close distance to establish direct contact and enable chemical reactions. However, continuum-scale reactive transport models typically neglect the role of mixing at the pore scale (and any other model-unresolved scales). This is partly because the precise link between a porous medium's micro-structure and its resulting mixing behavior has not been rigorously established yet; but also due to a lack of robust, generalized models and tools to account for local mixing and its upscaled effects. The goal of MixUp is to develop a first-of-its-kind upscaled transport modeling approach for mixing and reaction, founded on the underlying micro-scale physics, that can accurately account for local mixing in granular media, and that can be readily integrated within existing continuum-scale reactive models and codes. This will be attained by taking advantage of the recent "A Closer Look" simulation dataset, which contains the results of high-resolution Computational Fluid Dynamics simulations of pore-scale transport and mixing in granular media columns with an unprecedentedly large domain size, and also features different degrees of grain-size variability. A first implementation of the upscaled approach will be used to evaluate the importance of local mixing for reactive processes within mountain hillslopes.

Keywords: mixing,porous media,granular media,computational fluid dynamics,fluid mechanics,reactive transport,upscaling,high performance computing,lamellar mixing,heterogeneity
Bridging accessibility, participation and inclusion with automatic live subtitles (In4All)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-03-01
End date: 2027-02-28
Duration (months): 24.0
Total project cost (EUR): 191760.0
EU funding (EUR): 191760.0
Participants: 1
Project status: SIGNED

Background: Accessibility is usually understood as means of making cities more accessible for people with mobility disabilities. But accessibility encompasses also access to culture and information. Public institutions communicate with their residents and visitors through various channels. Yet, what about those who cannot access this information such as people with sensory disabilities or, as is common in the EU, people with different linguistic backgrounds? A way to provide universal access to audiovisual products is using automatic subtitling, an AI-based technology that automatically generates subtitles for pre-recorded and live audiovisual products. Aim: I will address the role of automatic subtitling in enhancing the accessibility of communication in public institutions and its potential impact on the well-being and civic engagement of citizens. Urgency: Advances in artificial intelligence have improved drastically the quality of live automatic subtitling, but we do not know how this technology impacts its users in several communicative situations, since there are no reception studies on this matter. Approach: This is an empirical and interdisciplinary study mixing ethnographic and experimental approaches. Using both qualitative and quantitative data collection tools, this is the first study investigating the interaction between live automatic subtitling and its end users. Innovation and impact: 1) Research into a new, unclaimed research avenue; 2) Interdisciplinary approach with data collection tools never used before on media accessibility; 3) Determine the impact of technology on reception of media accessibility; 4) Results will directly improve several stakeholders’ lives; 5) Results will be directly applicable to professional practice, promoting knowledge-based economy.

Keywords: translation,automatic subtitles,media accessibility
Exercised breastmilk: a kick-start for childhood obesity prevention (ExMilk)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Norway
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-03-01
End date: 2028-02-29
Duration (months): 60.0
Total project cost (EUR): 1891529.5
EU funding (EUR): 1891529.0
Participants: 1
Project status: SIGNED

Innovative preventive strategies are urgently required to halt the rising prevalence of childhood obesity given the inefficacy of current interventions. Mother-to-child transmission of obesity accounts for a large proportion of childhood obesity, more than what can be explained by genes. Nutrition during the first 3 months of life is crucial, with rapid weight gain in this period associated with subsequent obesity. Breastmilk is considered optimal for infant nutrition, but its composition depends on the mother’s metabolic health: the concentrations of some breastmilk compounds linked to infant obesity are associated with maternal body mass index. Maternal lifestyle factors, such as diet, can alter breastmilk composition. Little is, however, known about the effect of exercise during lactation. Exercise is a major regulator of systemic metabolism affecting multiple tissues and organs. In this ambitious, inter-disciplinary project, I will determine how exercise during lactation influences breastmilk composition in women with overweight/obesity and whether exercise-induced changes in breastmilk will influence infant obesity risk. My preliminary data show acute effects of exercise on breastmilk concentrations of adiponectin and lipid metabolites relevant for energy metabolism. In ExMilk, I will determine both acute effects and adaptations after regular exercise on a complex matrix of breastmilk compounds. By linking breastmilk data to comprehensive data for the infants, I will investigate the potential mechanisms underlying the effects of maternal exercise on infant obesity risk, mediated by changes in breastmilk composition. To reach my goals, I will perform gold-standard randomised trials and analyse biological samples from mothers and infants on multi-omics platforms. My experience in metabolomics and exercise intervention trials in reproductive-aged women will enable me to break new ground in understanding how exercise during lactation modifies infant obesity risk.

Keywords: childhood obesity,breastmilk,exercise,epigenetic modifications,randomised controlled trial,metabolomics,lipidomics,bioinformatics,inflammation,energy balance
Hybrid Imaging in the Catheterization Room (HICARE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2023-04-01
End date: 2024-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Hybrid Imaging in the Catheterization Room In the previously-completed ERC CoG, we have developed a patented c-arm scanner (called IXSI) which can accomplish real-time hybrid image guidance in dynamic environments such as the intervention and the catheterization room. Thus far, we have evaluated IXSI for oncological purposes. But more recently, we have identified a new potential application in the field of interventional cardiology, in which hybrid imaging may help for determining the culprit vessel during the interventional procedure or directly evaluating the outcome of a treatment. In this ERC Proof of Concept, we will explore whether the new proposed application of IXSI is worth pursuing further. We will perform four tasks: i) we will investigate for which groups of cardiology patients or treatments IXSI may provide the greatest benefit and assess their market share, ii) we will evaluate the performance of IXSI for cardiology by developing custom-made testing devices, iii) we will investigate whether IXSI can be made more cost-effective for cardiology by making hardware modifications, and iv) by combining the information from the previous activities, we will develop a business case of IXSI specifically for cardiac interventions. Should it be demonstrated that IXSI can aid cardiac interventions, then we expect that our developed technology will be much quicker implemented in the clinic seeing that the proposed application field is massive and the incentive for commercialization would be greater (close to 1 million PCI procedures are performed per year in the US alone).
Gurdwara Architecture in the diasPora. Understanding the effects on (non-)Sikhs to build an inclusive urban environment (GAP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Singapore
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2027-08-31
Duration (months): 36.0
Total project cost (EUR): 315803.52
EU funding (EUR): 315803.52
Participants: 3
Project status: SIGNED

Religions increasingly materialize inside secular buildings with aesthetic and architectural characteristics which produce impacts that are still underestimated in the process of social interaction and urban inclusion. The GAP project aims to study these effects by exploring for the first time the opinion of (non-)users regarding the materiality and aesthetics of gurdwaras built in countries concerned by Sikh-punjabi diaspora. The emblematic case of Italy, a country that is home to 58 of the 140 gurdwaras in the EU (after Brexit), will be examined. Here, Sikh temples are pre-existing warehouses located in industrial and artisanal areas that communities are unable to fully convert. To better understand and act on such hybrid materialities, the GAP will also examine the views of (non)gurdwara users in the city-state of Singapore, an early destination of the Sikh-Punjabi diaspora (mid-19th century). Here, they are mostly located in the city center and their architecture resembles the 'iconic' forms of the Sikh temples of Punjab. The research will consider a representative sample of four Sikh temples that will be examined through a trans-disciplinary approach (geography, urban studies and religious studies) and a methodology that integrates traditional qualitative research techniques, including participatory activities, with Digital Humanities. The GAP will provide new empirical material to help build effective European governance of religious diversity in terms of inclusion and social interaction. It will also contribute to the process of legal recognition of Sikhism in Italy. The GAP will be conducted over the course of 36 months at the University of Rome “La Sapienza” (prof. Alessandro Saggioro). The outgoing phase will be carried out at Singapore University Management (Prof. Orlando Woods). GAP also provides for an 8-month secondment at the Bruno Kessler Foundation (Italy; prof. Massimo Leone).

Keywords: sikhism,diaspora,gurdwaras,architecture,materiality,aesthetic,social interaction,urban inclusion,italy,rome,singapore
New MOBility solutions for clImate neutraLity in EU cITIES (MOBILITIES FOR EU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Climate neutral and smart cities
Destination: Climate neutral and smart cities
Action type: Innovation actions
Countries involved: Spain,Germany,Finland,Slovakia,Bosnia and Herzegovina,Poland,Greece,France,Switzerland
Call: Co-designed smart systems and services for user-centred shared zero-emission mobility of people and freight in urban areas (2Zero, CCAM and Cities’ Mission) (HORIZON-MISS-2023-CIT-01, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 28945012.89
EU funding (EUR): 24743622.5
Participants: 29
Project status: SIGNED

MOBILITIES FOR EU aims at demonstrating that innovative passenger mobility and freight transport concepts designed and implemented following participative and user-center principles are cost-effective and feasible solutions to contribute significantly to the cities’ transformation towards climate-neutrality, allowing to speed up the process even to reach SCOPE 2 emissions reduction in 2030. Madrid (Spain) and Dresden (Germany) will implement 11 pilots comprising 27 very innovative solutions for mobility of people and freight, exploiting the combined potential of electrification, automation and connectivity, from the design to the implementation and evaluation stages acting as Lead Cities (LC). Both cities also ambition to act as pioneers of this process, taking advantage of multiple already existing initiates of social engagement and empowerment that will be integrated in the idea of Urban Transport Labs (UT-Labs), conceived as Innovation Hubs with the aim of fostering faster upscaling and replicability at EU level, making 5 Replication Cities (Ioaninna–Greece, Trencin–Slovakia, Espoo-Finland, Gdansk-Poland and Sarajevo-Bosnia&Herzegovina) through their own UT-Labs direct participants of the processes and later on main protagonists of their own designs.

Keywords: autonomous evehicles,freight fleets,5g
Clean Aviation Support for Impact Monitoring (CLAIM)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Aviation
Action type: Coordination and support actions
Partnership: CLEAN-AVIATION (JU-JTI)
Countries involved: Germany,Netherlands,Italy,France,Belgium
Call: Aviation Climate and Technology Impact Monitoring Methodology (HORIZON-JU-Clean-Aviation-2023-01, 2023)
Start date: 2024-01-01
End date: 2025-06-30
Duration (months): 18.0
Total project cost (EUR): 749625.0
EU funding (EUR): 749625.0
Participants: 5
Project status: CLOSED

The CLAIM proposal main high-level objectives are: 1. To obtain an answer on how to best translate the Clean Aviation Programme objective to reduce net greenhouse gas emissions by -30% versus state of the art into tangible metrics in terms of measurable engine tailpipe emissions, by a. Collecting, analysing and establishing the current level of scientific understanding within the worldwide community of climatology and atmospheric sciences, and of aviation climate impact and its greenhouse gas emissions contributions; b. Identifying knowledge gaps, barriers, and needs for research in view of orienting more appropriately the technology research streams for future green and zero-emission aircraft. 2. To compile an inventory of relevant aeronautical advanced research activities and technology areas, not only from the aviation community but potentially also from other sectors if relevant by a. Reviewing and analysing aeronautical literature on “disruptive aircraft concepts” or greener aircraft as well as on climate-neutral aviation in general, including their (preliminary) environmental performance/results; b. Proposing a way forward and an approach that highlights the assumptions and metrics used to reconcile the numbers and the prospects of performance improvements for the main technologies; c. Categorising these concepts in terms of aerodynamics, structural, systems and propulsion technologies and their associated benefits at aircraft level, as well as performing a technology mapping; d. Performing a preliminary performance assessment using proposed assumptions and criteria for an SMR and an HER. Consequently, through achieving its objectives, the CLAIM proposal assists Clean Aviation, EC and EASA by providing more clarity and contributing to all of the expected outcomes

Keywords: impact monitoring,impact assessment,climate impact assessment,aviation,clean aviation
Real-time flow and flux measurements for combating groundwater supply and pollution. (iFLUX)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Belgium
Call: EIC Accelerator Open 2021 (HORIZON-EIC-2021-ACCELERATOROPEN-01, 2021)
Start date: 2022-07-01
End date: 2024-10-31
Duration (months): 28.0
Total project cost (EUR): 3464312.89
EU funding (EUR): 2425019.02
Participants: 1
Project status: CLOSED

iFLUX’ mission is to make groundwater visible! We have raised €1.36 million in equity & €1,185k through straight & convertible loans. With revenues from our developed paid projects, we brought our first product into the market: a passive flux sampler to measure & monitor 127 types of pollutants in the ground(water) and determine their impact. Today, our sampling technology has been used by 100+ customers across the EU and generated revenues €750k+. These customers include companies such as DOW, Total, ERM & Arcadis. A scalable real-time groundwater flow & flux sensing probe is our urgent development pipeline because monitoring groundwater dynamics is complex and requires highly accurate & real-time data to create a better understanding of aquifer behavior over time and spatially. With our sensing probe, we will be the next generation water monitoring solution by visualizing and integrating the dynamics of groundwater and its pollution.

Keywords: water quality monitoring,soil remediation,restoration,groundwater contamination,onsite quality measurement,remote data collection and analysis
The Economics and Politics of Alternative Realities (ALTREALITY)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: Sweden
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2024-10-01
End date: 2029-09-30
Duration (months): 60.0
Total project cost (EUR): 1297878.0
EU funding (EUR): 1297878.0
Participants: 1
Project status: SIGNED

Many people hold systems of wrong beliefs, which combine into a semi-coherent alternative reality based on the sinister motives of influential actors. I build models of the supply of and demand for such alternative realities. The key idea is that people believing in alternative realities misperceive not only features of the environment but also the incentives of other actors. Applications of my supply side framework include the analysis of political conspiracy theories that serve to discredit the intellectual elite, fear mongering to prompt mobilization in a conflict, and anti-state narratives that serve to generate political support for fiscal conservatism. My demand side approach formalizes the idea that individuals believe in alternative realities to protect a set of core beliefs fundamental to maintain their preferred identities. These models explain stylized facts in domestic and foreign politics, and generate new predictions which I test.

Keywords: alternative reality,propaganda,misinformation,populism,conflict,media,welfare program implementation
Tailoring and Extending Chemically-assisted Spinning to Textiles Incorporating Liquid crystal-Enhanced functionality (TECHSTILE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Luxembourg,Portugal,Switzerland
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 175920.0
EU funding (EUR): 175920.0
Participants: 3
Project status: SIGNED

Responsive and smart textiles are a next frontier of research to add new, useful functionality to commodities we already use in our day-to-day lives. By allowing us to replace energy-consuming electronic sensors for detecting or responding to stresses and harmful conditions, they can contribute to a safer, greener, and more sustainable world. The jump from concept to product, however, has been fraught with issues: how can we incorporate novel materials of interest, such as liquid crystals or colloidal suspensions with a liquid armor functionality into fibers that we can then incorporate into textiles? In this project, I will use a microfluidic wet spinning technique I developed to incorporate functionality into fibers made from textile-grade polymers smart, yet comfortably wearable garments. I will focus on two functionalities: responsiveness to volatile organic compounds, enabled by liquid crystals, and responsiveness to ballistic impacts, provided by liquid armor. I will assess the performance of these fibers to the applied stresses as well as incorporate them, using embroidery and weaving, into fabrics and evaluate their performance in prototype wearable garments.

Keywords: fibers,spinning,liquid crystals,liquid armor,microfluidics,wet spinning,polymers,sensing
Improving cancer therapy by identification of novel drug leads modulating transcription termination bridging molecular biology and therapeutic applications (ModulatEnds)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Poland
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2026-01-01
End date: 2027-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Our value proposition is improving cancer therapy by identification of novel anti-cancer candidate drug leads modulating transcription termination, bridging molecular cancer biology and therapeutic applications. We have developed a methodology to directly measure alterations in transcription termination and successfully subjected it to miniaturization and automatization processes. We are applying for funding to validate a screening platform to identify small molecule inhibitors of transcription termination.