Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Towards a postgrowth economics: A viable postgrowth economy without increasing inequality (PostGro)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-04-15
End date: 2022-04-14
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: CLOSED

Economic growth seems unlikely to continue at current rates, if at all. But we currently do not have a plan of how to manage a postgrowth economy. This represents a major impediment to formulating policies for how the EU may best pursue its objectives for development, environmental protection, and the elimination of poverty in a future postgrowth economy. There is debate over whether our current economic system based on interest-bearing debt can be made viable postgrowth, and evidence that even slowing growth leads to increasing inequality. Here, I propose research to integrate existing theoretical research into postgrowth viability with research into measures to prevent inequality from increasing. Since no industrial economy has yet experienced prolonged periods of very slow or negative growth, I will test the predictions against historical case studies. The project will achieve four objectives: to identify the parameters in which a postgrowth economy is viable; to identify the parameters in which continually increasing inequality is also avoided; to test these parameters against historical case studies; and to draw on these results to evaluate policies for producing a postgrowth economy that is both viable and avoids inexorably increasing inequality. The fellowship will allow me to broaden and deepen my knowledge of ecological economic approaches to postgrowth whilst bringing my knowledge of property economics, comparative institutions, and historical postgrowth to my hosts at ICTA. We will disseminate the results to academics and policy makers, with the historical aspect making quite technical debates much more accessible for communication to a wider public. The fellowship will place me, and ICTA, at the forefront of the emerging field of theoretical and historical postgrowth research. I have developed a realistic implementation plan together with my hosts at ICTA, a world-leading centre for research into postgrowth.

Keywords: political ecological economics,ecological macroeconomics,postgrowth,degrowth,sustainability,institutions,property,distribution,inequality,interest,debt,wealth,capital
Calix[4]pyrrole for p-block elements: anti-van’t Hoff-Le Bel configuration and ligand-element cooperativity revive the standard oxidation states. (pCx4All)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2020-11-01
End date: 2025-10-31
Duration (months): 60.0
Total project cost (EUR): 1499500.0
EU funding (EUR): 1499500.0
Participants: 1
Project status: SIGNED

State-of-the-art strategies for p-block element-based bond activations predominantly rely on the activity of low-valent species (e.g., silylenes). However, during bond activation, those species usually collapse into the deep thermodynamic sinks of their standard oxidation states, precluding any catalytic cycles. The present proposal pCX4All develops new concepts that add unique reactivity to the p-block elements Al, Ga, Si, Ge, Sn and P in their stable oxidation states. This is achieved by the generation of planar anti-van’t Hoff/Le Bel configurations, ligand-element cooperativity, and p-block valence isomerism. All those original features are enabled by calix[4]pyrrole – a well-established ligand for transition metals – which has never been used for p-block elements. Challenging bond activations (e.g. dinitrogen) and catalytic transformations (e.g. water splitting and acceptorless dehydrogenative oxidation of alcohols) are tackled with the most abundant elements of the earth crust (e.g. a square-planar, tetracoordinated silicon(IV) or aluminum(III)). The concepts are supplemented by photo-induced reactivity and extended into the field of dynamic covalent chemistry. An integrated synthetic, spectroscopic and theoretical research approach guides the way from fundamental understanding to the application in catalysis and materials. Importantly, general feasibility was recently provided by the successful isolation of the first square-planar coordinated aluminum(III) anion in our laboratories, including the observation of its exciting reactivity. We believe that these objectives will initiate a renaissance of p-block element chemistry in their standard oxidation states, equipped with exceptional reactivity by strong structural constraint and ligand-element cooperativity.

Keywords: p block element chemistry,geometrical constraint
Improving Design, Evaluation and Analysis of early drug development Studies (IDEAS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Austria,Germany,Italy,Germany,Germany,Belgium,France,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 3108939.48
EU funding (EUR): 3108939.48
Participants: 10
Project status: CLOSED

Drug development is a long and costly process which suffers from the major shortcoming that frequently failure is often only determined during the final stage. Recently, it has been recognised that more care needs to be taken during the early stages of development to avoid going into lengthy and costly confirmatory studies with ineffective or harmful treatments. To achieve this goal it is essential to implement efficient methods for the design and analysis of such early development studies. The expertise in this area is, however, limited at the moment and adequate methodology is only partially available. Using a cross-sectorial, transnational approach, the IDEAS network brings together leading public and private sector researchers in the field with ample experience in training to educate, promote and support the future leaders in medical statistics in general and in the design and analysis of early developmental studies in particular. Within the network, cross-sectorial, transnational teams will support young researchers with individual methodological projects and devise an individually tailored training programme for them. Clinical advisors supplement the input of the supervisory team and ensure practical relevance and uptake of the methods devised. The training activities are comprised of a well-rounded mix of specialist, methodological components and generic, transferable skills. A mandatory set of networkwide training activities is supplemented by individual training components and cross-sectorial secondments, and particular attention is given to interaction and collaboration between researchers and supervisors across public and private sector partners. At the end of their training the researchers will be uniquely qualified with expertise in the field, benefit from experience in both public and private sector and can rely on a wide network of experts in the field in the future.

Keywords: early phase clinical studies,adaptive designs,statistical modelling
Transnational Localism and Music after the two World Wars: the case of Francis Poulenc (Transnational Localism)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2017-08-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 2
Project status: CLOSED

This project looks at the role composers played in the construction of European culture in the aftermath of two World Wars. Taking Francis Poulenc as an example of a French composer who experienced war twice, it looks at his creative responses to the wars. It prioritises the musical and cultural significance of localised urban, suburban and rural places in shaping a distinctive musical and national identity, an identity that was recognised by his contemporaries as representing a generation; it also scrutinises his international activities in pursuit of cultural and artistic co-operation, collaboration and exchange. The project includes a study of Poulenc’s UK connections, using understudied archival materials to explore his collaborations with composers such as Britten and Lennox Berkeley, his presence in concert life and his clandestine WWII activities with the BBC. It also examines the significance of the European-American artistic exchanges from the post-WWI period as a form of cultural co-operation and propaganda. Transnational Localism shows the extent to which creative artists reflected the trauma of conflict, contributed to peace-building and to national and European identity on a cultural level and participated in politics without needing to be explicitly politically engaged. Musicology was identified as an area of strategic priority by the European Science Foundation, Standing Committee for the Humanities in 2008. This project responds to this challenge by exploring the role of music in shaping identities on individual, generational, national and European levels. It also takes the inherent interdisciplinary nature of musicology a stage further by designing a training programme and research project that is multidisciplinary with the aim of establishing research cooperation that is of mutual benefit to European and Anglophone scholarly traditions in the Humanities and Social Sciences.

Keywords: poulenc,music,transnational,artistic exchanges world wars,urban,suburban,rural,britten,berkeley,cultural and emotional geographies,reconstruction,france,belgium
INnovative DIagnostiCs for BANana paThogens Surveillance (INDICANTS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: South Africa,France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2022-01-01
End date: 2024-12-31
Duration (months): 36.0
Total project cost (EUR): 219050.88
EU funding (EUR): 219050.88
Participants: 2
Project status: SIGNED

Bananas are major staple in developing countries and the most eaten fruit in Europe. Global banana production is constrained by several diseases that are responsible for yield losses and low productivity of bananas and severely compromise food security. Particularly banana production is seriously threatened by four vascular diseases, Fusarium wilt disease of banana caused by the fungus Fusarium oxysporum f.sp. cubense (Foc), Moko and banana blood diseases, caused by Ralstonia solanacearum and R. syzygii subsp. celebesensis, respectively) and Xanthomonas wilt of banana caused by Xanthomonas vasicola pv. musacearum. Efficiency of surveillance and plant disease management requires the availability of Point of care (POC) diagnostics that can be operated directly on site. INDICANTS project focuses on (i) the development of a low-cost multi-pathogens LAMP (Loop-mediated isothermal amplification) detection kit, and its validation via an interlaboratory test and field surveys. (ii) the evaluation of an emergent technology (CRISPR/Cas12a) for the diagnosis of Foc. (iii) the test of an innovative microneedle patch for DNA extraction from plant. This project relies on a two-way transfer of knowledge and expertise between the applicant and Stellenbosch University: the applicant will access to areas where the diseases are present, will acquire through hands-on training and training-through-research, new expertise and skills in genetics/biotechnology, thereby strengthening the future career prospects. The partner organisation will gain experience and knowledge on bacterial banana diseases and LAMP method. Actions of protection and exploitation of the outputs will be set up, with the involvement of an industrial partner. Besides the scientific publications and conferences, the results will be disseminated to different audiences: the general public (website, press and TV), plant protection services (workshops) MSc students (lectures), schoolchildren (Platform visits).

Keywords: banana phytopathogenic bacteria and fungi fusarium oxysporum f sp cubense ralstonia spp xanthomonas vasicola pv musacearum point of care diagnostics lamp crispr,cas12a field survey
Training the next generation of archaeological scientists: Interdisciplinary studies of pre-modern Plasters and Ceramics from the eastern Mediterranean (PlaCe)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Cyprus,Belgium,Greece,Czechia,United Kingdom,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2021-03-01
End date: 2025-02-28
Duration (months): 48.0
Total project cost (EUR): 3868438.32
EU funding (EUR): 3868438.3200000003
Participants: 8
Project status: SIGNED

PlaCe is a state-of-the-art, interdisciplinary ETN that aims at training-through-research the next generation of archaeological scientists, integrating a wide range of theoretical and analytical methods for the comprehensive study of pre-modern plasters and ceramics, the first synthetic materials produced by humankind. The interdisciplinary study of these materials from the pre-modern eastern Mediterranean, as well as the technologies, technological know-how, raw materials, and tools developed and employed through the millennia for their production, will provide the framework for the implementation of high-quality training that will assist the recruited early-stage researchers to face current and future challenges in the fields of archaeological sciences and cultural heritage. The eight universities and research centres composing the consortium of PlaCe will join forces in partnerships with other universities and entities from the public and private sectors, in order to facilitate the researchers’ mobility, to develop their analytical and transferable skills, and to increase their employability. At the same time, the multiple individual research projects accommodated by PlaCe will contribute to our enhanced understanding of the evolution of plaster and ceramic premodern technologies, and their adoption in differing social settings, contributing to the history and archaeology of Europe and the eastern Mediterranean.

Keywords: archaeological sciences,eastern mediterranean,pre modern material culture,plasters,ceramics,laboratory analytical equipment,material properties
A novel and intuitive communication interface providing life enriching experiences for users in risk of social exclusion (IrisPhone)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Cyprus
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2015, 2015)
Start date: 2016-03-01
End date: 2016-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

IrisPhone was born in early 2014 as an entrepreneurial project of two young Cypriot engineers who have set out to reduce the digital divide by designing a novel and intuitive communication interface for smartphones that requires neither key or touch-screen pressing nor voice-based commands. IrisPhone delivers technology innovation, but also social innovation, by enabling its target users, mainly elderly people, to remain connected and avoid risk of exclusion. Today, almost 2 years into development, and after raising funds which led to the expansion of the team and the foundation of iResTech Ltd, the first IrisPhone prototype has already been successfully tested with a wide group of elderly users in Cyprus. In light of these results, MTN Cyprus, subsidiary of the multinational mobile telecommunications company with more than 230 million users, has expressed its interest in incorporating our future product into its retail space. Consequently, we anticipate to generate an accumulated net profit of €4,6 to €8,9 million (depending on which business model is chosen) within the first five years of commercialisation. With the SME instrument’s support, iResTech Ltd aims to explore, plan and finally execute a business plan for the upscale, demonstration and future market introduction of IrisPhone.

Keywords: human communication interface,social connectivity,social inclusion of seniors
Biomechanics and signaling in models of congenital heart valve defects (EVALVE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: France,United Kingdom
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-12-01
End date: 2024-05-31
Duration (months): 90.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 798871.86
Participants: 2
Project status: SIGNED

Mechanical forces are fundamental to cardiovascular development and physiology. The interactions between mechanical forces and endothelial cells are mediated by mechanotransduction feedback loops. My lab is interested in understanding how hemodynamic forces modulate cardiovascular function and morphogenesis. Overall, our recent work is unraveling the biological links between mechanical forces, mechanotransduction and endothelial cell responses. The heart beats 2.6 billion times in a human lifetime and heart valves are amongst the most mechanically challenged structures of the body. The cardiac valves are made of endocardial cells (EdCs) and extracellular matrix components. Most valve diseases have their origins in embryogenesis, either as signs of abnormal developmental processes or the aberrant re-expression of fetal gene programs normally quiescent in adulthood. This project is directed towards the elucidation of the biomechanical mechanism of mechanotransduction at the subcellular and molecular level and in addressing how EdCs integrate this information to form and maintain a functional cardiac valve. We will identify the mechanosensors at work in EdCs and their roles during cardiac valve development and repair. To do so, we will implement unique optical methodologies the lab has pioneered to characterize endocardial mechanotransduction: 1) Optical tweezing combined with mechanical stress reporters to test the mechanosensitivity of EdCs; 2) High resolution live microscopy and mathematical modeling to quantify mechanical forces; 3) 3D cell lineage studies to understand how cells respond and organize during pathological valve development. We will also use high-throughput mRNA- and ChIP-sequencing to characterize the transcriptional network activated by forces. When completed this proposal will shed light on a critical, but little explored, aspect of congenital valve defects and will be useful for identifying new targets for therapeutic interventions.
Digital acne assessment tool enabling acne diagnosis in cost and time efficient way (ScanZ)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: SME instrument
Countries involved: Serbia
Call: Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-09-01
End date: 2019-08-31
Duration (months): 36.0
Total project cost (EUR): 2304782.5
EU funding (EUR): 1613347.75
Participants: 1
Project status: SUSPENDED

In the Healthcare industry, digital health-care solutions will become vital in order to ensure a sustainable and efficient health system in both a time and cost effective manner. mySkin d.o.o, aims to significantly contribute in creating innovative and sustainable principles in the Healthcare market, by improving the quality of life for acne sufferers and working conditions for medical professionals. mySkin proposes an innovative ICT concept for a digital skin-care service based on acne sufferers and dermatologists, applying new sets of rules, values and model to the health-care market, which ultimately disrupts the existing traditional skin care market. Up to now, acne assessment was only possible visiting dermatologist and traditional acne assessment was a time and money consuming procedure. Nowadays the progress of software solutions combined with the point of care devices can for the first time offer a better and cheaper alternative to the millions of acne sufferers and thousands of dermatologists The overall objective of ScanZ project is to move the system from technology readiness level 7 to 9, making the device clinically and commercially qualified for the market. The expected outcome of the project is to start the full commercialization of the ScanZ device at the end of PH2 as a medically certified IP protected user-centred designed system to be sold to hospitals. During the first medical trial at ORS Hospital Belgrade, mySkin obtained significant positive feedback from patients and medical professionals; and whilst scouting the dermatology clinics for holding medical trials during the PH2 project ScanZ has received strong interest from dermatology clinics across Europe as well as positive reviews from TechCrunch, CNET, NY Daily News, and the BBC.

Keywords: digital medical device,medical device,acne,diagnostic device,point of care devices,acne sufferers,imagining device,health care,acne assessment,dermatology,e health,m health