Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Multiscale Modelling of the Neuromuscular System for Closed Loop Deep Brain Stimulation (DBSModel)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Ireland
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-08-01
End date: 2021-07-31
Duration (months): 72.0
Total project cost (EUR): 1999474.0
EU funding (EUR): 1999474.0
Participants: 1
Project status: CLOSED

Deep brain stimulation (DBS) is an effective therapy for treating the symptoms of Parkinson’s disease (PD). Despite its success, the mechanisms of DBS are not understood and there is a need to improve DBS to improve long-term stimulation in a wider patient population, limit side-effects, and extend battery life. Currently DBS operates in ‘open-loop’, with stimulus parameters empirically set. Closed-loop DBS, which adjusts parameters based on the state of the system, has the potential to overcome current limitations to increase therapeutic efficacy while reducing side-effects, costs and energy. Several key questions need to be addressed before closed loop DBS can be implemented clinically. This research will develop a new multiscale model of the neuromuscular system for closed-loop DBS. The model will simulate neural sensing and stimulation on a scale not previously considered, encompassing the electric field around the electrode, the effect on individual neurons and neural networks, and generation of muscle force. This will involve integration across multiple temporal and spatial scales, in a complex system with incomplete knowledge of system variables. Experiments will be conducted to validate the model, and identify new biomarkers of neural activity that can used with signals from the brain to enable continuous symptom monitoring. The model will be used to design a new control strategy for closed-loop DBS that can accommodate the nonlinear nature of the system, and short- and long-term changes in system behavior. Though challenging, this research will provide new insights into the changes that take place in PD and the mechanisms by which DBS exerts its therapeutic influence. This knowledge will be used to design a new strategy for closed-loop DBS, ready for testing in patients, with the potential to significantly improve patient outcomes in PD and fundamentally change the way in which implanted devices utilise electrical stimulation to modulate neural activity.

Keywords: neural engineering,electrical stimulation,deep brain stimulation
Our first steps to Europe: Pleistocene Homo sapiens dispersals, adaptations and interactions in South-East Europe (FIRSTSTEPS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Germany,Italy
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2022-04-01
End date: 2027-03-31
Duration (months): 60.0
Total project cost (EUR): 3306062.0
EU funding (EUR): 2583562.0
Participants: 2
Project status: SIGNED

Despite recent discoveries in human evolution, the origin of our species, Homo sapiens, and the process through which it expanded and became established around the globe remain murky. Increasingly, it is viewed as a dynamic process of population expansions and contact among human lineages, occurring in concert with the Pleistocene climatic oscillations, which influence the probability of human survival as well as the availability of land bridges enabling expansions. Dispersals and population contact, therefore, may have been the norm in human evolution and may have played a greater role in shaping our species than previously recognised. In such a model, South-East Europe emerges as a likely area of sustained and / or repeated contact, making this region critical for testing hypotheses about European deep prehistory. Despite this crucial role, however, paleoanthropological research there remains in its infancy, with little existing data and no overarching interpretive framework. FIRSTSTEPS aims to fill this research gap by applying inter-disciplinary cutting edge investigation to recover new and connect existing evidence across sites, periods and regions. Key sites / finds from South-East Europe (Greece, Serbia, Bosnia, Montenegro, Croatia, Romania) and Italy — whose better documented record has yet to be connected to its counterparts to the East and will provide a crucial comparative perspective — will be included. In-depth analysis of important fossil / cultural assemblages from specific chrono-cultural periods ca. 200-30 ka, will be conducted to identify patterns of biological and cultural variation. In parallel, regional and supra-regional perspectives will be constructed beyond individual sites /countries. By addressing this crucial research gap FIRSTSTEPS will take paleoanthropological research in this important region to the next level and squarely place it on the paleolithic map of Europe.

Keywords: human evolution,dispersals,adaptation
Addressing Attractiveness of Science Career Awareness (SciCar)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Israel,Estonia,Finland
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2020-10-01
End date: 2024-03-31
Duration (months): 42.0
Total project cost (EUR): 899031.25
EU funding (EUR): 899031.25
Participants: 3
Project status: SIGNED

SciCar - a science education project - addresses the need to systematically raise the level of expertise among researchers and educators who are involved in science & technology (S&T) education within UT and associated institutions, currently seen as ineffective in making science teaching careers attractive and enabling teaching to adopt more relevant, context-based approaches. The project especially addresses, via a Twinning partnership, bringing in expertise from top level science education countries - Israel and Finland, particularly focusing on enhancing career awareness, enabling a capable workforce, and on promoting science-related careers. The major outcome is envisaged as a centre of excellence at UT in science education, interacting with all STEM teacher education bodies and the science education community e.g. science centres, science teacher associations. This is seen as enabling appropriate models for enacting a change of paradigm related to teacher education and science career awareness. A major focus is put on (1) reducing the gap between scientist and science educator beliefs in the training emphasis of future STEM-related teachers, (2) the involvement of the science education community in making the teaching profession more attractive, (3) thus determining key ways & appropriate models for instituting a paradigm change with a view to increasing the number of STEM-related teachers, (4) and giving emphasis to competence development in promoting science-related career awareness. The created centre is to become a platform ensuring that science researchers are guided to embrace science education expertise, making the preparation for science-related teaching careers more attractive while applying excellent knowledge in research (and approaches to undertake research) in coaching the next generations of science education researchers. The project seeks to identify best practice on knowledge transfer between science development and science education.

Keywords: science education,career awareness,staff professional development,teacher training,work and life skills,science and social science research,early career researcher,stem disciplines
Metal-air battery integration for cargo compartment fire suppression (O2FREE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Spain,Spain,Belgium
Call: Oxygen Absorbing Metal-Air-Batteries for Long Term Cargo Compartment Inertisation (H2020-CS2-CFP11-2020-01, 2020)
Start date: 2020-12-01
End date: 2022-11-30
Duration (months): 24.0
Total project cost (EUR): 799197.5
EU funding (EUR): 799197.5
Participants: 3
Project status: CLOSED

Today, most aircraft still use Halon-based fire suppression systems for cargo compartment inertisation following a fire event. Halon 1301 is a very effective fire extinguishing agent. However, it is also a harmful substance with high ozone depletion potential. The use of halon for critical applications including aviation is being phased out, and will be completely banned by 2040 as set out in the Montreal Protocol. There is a need for innovative, lightweight and more environmentally-friendly fire suppression solutions for the aerospace sector. O2FREE proposes the development of an innovative and lightweight solution for fire suppression based on primary Al-air battery technology. Metal-air batteries consume oxygen during discharge and thus have the capability to suppress fires in closed compartments such as aircraft cargo bays by reducing oxygen concentration. O2FREE will demonstrate the feasibility of such technology. Battery gravimetric power capacity is considered the critical factor for reaching high oxygen absorption capability. O2FREE proposes the development of Al alloys (anode) and nanofibers with optimum porosity (cathode) to enhance Al-air cell power capability. Moreover, 1S12P module configuration will be developed to maximize power output of the battery module and thereby oxygen absorption rate per kg of battery. Battery prototypes containing single battery modules will be developed for testing and validation. Modules will be placed in aluminium casings designed for protection and to allow air to reach cells, meeting the standards of aeronautics sector including RTCA DO160 Rev G. O2FREE will demonstrate the feasibility of Al-air technology as a fire suppression solution for aeronautics; delivering a lightweight, safe and reliable technology free of critical raw materials. Results will directly contribute to EU competitiveness in aircraft systems and technologies.

Keywords: metal air,battery,fire suppression,cargo compartment,inertisation,aircraft
POM: Peace of Mind for everyone's invoice administration (tap.pay.store)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Belgium
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-05-01
End date: 2018-11-30
Duration (months): 7.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

POM = Peace of Mind. POM is our beyond state-of-the-art patented invoice payment platform, meeting TRL7, which will disrupt the EU invoice payment market, adding value to both biller and end-user. Our flagship mobile app (to pay, manage & archive any invoice from any biller – both paper and digital) enables invoice admin on-the-go. POM saves up to 97% of the time needed to process invoices and reduces late payments with up to 33%. POM is easily accessible and very convenient, but at the same time offers the security, reliability and confidentiality customers expect in their financial affairs. POM will commercialize its platform on EU scale. The value of m-payment transactions in the EU-7 is expected to jump from €52 bn in 2016 to €125 bn by 2021. With its top-down + bottom-up go-to-market strategy, POM targets a dominant position of up to 30% market share per targeted country by 2022. POM (°2014) has grown into a dynamic team of 8 people. POM has a strong management team with wide experience in e-invoicing and e-payments, amounting to a combined +35 years. POM is well connected at a national and international level. Our CEO is a delegate to the EU Forum on e-Invoicing, and an active member of the EU E-invoicing Service Providers Association (EESPA) and the EU Retail Payments Board (ERPB) working group. The team is regularly consulted by the Belgian government. POM has won various prizes and nominations. Launched in May 2016 on the Belgian market, POM now reaches up to 200 000 users and +2 500 billers from all sectors, i.e. up to 15% market penetration after only 1.5 years. POM closed deals with EDF (2nd largest energy company in EU), bpost (leading BE post operator) and ING (world leading banking group) increasing its user reach and customer base, and set up a long-term strategic partnership with Worldline (EU market leader in payment/transaction services). Business coach Charles Bryant, EU authority in the field of e-invoicing and e-payment, will coach us.

Keywords: invoice payment platform,smartphone app,mobile payments,machine learning
Valves for OiL regulaTion with High AccuracY and REliability (VOLTAYRE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: France
Call: Oil flow 4 channels regulation valves (H2020-CS2-CFP08-2018-01, 2018)
Start date: 2019-03-01
End date: 2022-03-31
Duration (months): 37.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 1400000.0
Participants: 1
Project status: CLOSED

The objectives of the project VOLTAYRE is to design, develop, manufacture, test and qualify an innovative TRL 5 oil valve (OV) able to regulate accurately two oil flows to the gearbox and the engine of the Ultra High Bypass and High Propulsive Efficiency Geared Turbofans and its oil system, and reject the remaining extra flow coming from the oil pump to the tank. This valve will also communicate to the FADEC the delivered flows and allow the FADEC to close the loop via valve’s commands. The VOLTAYRE proposal innovation is based on the innovative low energy limited angle torque motor (LATM) developed and patented by FACT for similar application. This torque motor is able to provide high torque, high displacement, high ageing stability, without dynamic seals to direct drive both a rotary metering direct drive valve (RMDDV) or a rotary split direct drive valve (RSDDV). The RMDDV is coupled with a three-way delta pressure regulator (DPR). This DPR is able to regulate a constant delta pressure between the inlet and the outlet of the RMDDV. This DPR will be able to reject the extra flow provided by the pump to the tank and regulate a constant differential pressure across the RMDDV Two identical differential pressure flowmeters (DPF) located after the RSDDV, one for the engine line the other for gearbox line, able to provide the requested high accuracy with the necessary reliability in this harsh environment. As part of this response, we have proposed an architecture of equipment possible by combining different bricks TRL3 or 4. These bricks are however a capacity to be organized differently, to provide other architectures for the equipment according to the detailed needs that the topic leader will express through its specification

Keywords: valves,regulation,flow,4 channels,accuracy,reliability
SaaS platform for automated categorisation and mapping of digitised documents using machine intelligence semantic extraction (OMNIUS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2019-03-01
End date: 2021-02-28
Duration (months): 24.0
Total project cost (EUR): 2213420.0
EU funding (EUR): 1549394.0
Participants: 1
Project status: CLOSED

Today, enterprises, consultants and clerks manually process data from arbitrary documents (such as insurance policies, contracts, claims, etc.) to enter the necessary process data into their core ERP systems. As a result, it still relies on the physical availability of employees, and is therefore hardly scalable and sensitive to human error. Automation of document processing operations is challenging due to the variety of processes involved, the requirement for high-level recognition technologies, high demands on accuracy, and the versatility of enterprise IT systems. Qidenus Group GmbH was founded in 2015 in Berlin, offering innovative software-based document management services. It has been our mission to support archives and operational processes to unlock information from all types of documents with our SearchInk technology, which combines Machine Learning, Semantic Processing and Layout and Structure Analysis. Now, we want to implement SearchInk into the B2B-market by offering omni:us, a highly scalable, digitalised SaaS-platform for automated data classification, extraction and the hand-over process to core ERP-systems in the business segment of Claim Management as beachhead market. Thanks to the performance of omni:us, the efficiency, speed and quality of data extraction and archiving will be dramatically increased, resulting in reductions of working time to <5% and costs up to 90%. The use of omni:us will offer enterprises a 100+% increase in turnover, 85-95% reduction of labour time spend, and automatically declining error rates (<5%). In this Phase 2 project, we intend to further deploy the omni:us SaaS architecture from a technological perspective with improved SearchInk technology performance, and Claim Managementspecific functionalities in a SaaS environment. Also, to grow our business, we want to create API´s to expand the compatibility with common ERP-systems and develop the market to ensure successful market launch.

Keywords: saas platform,automated document processing,artificial intelligence,digitisation of business,processes,automated semantic data extraction,automated document classification,visual,computing
Industrial Biotechnology Innovation and Synthetic Biology Accelerator Preparatory Phase (PREP-IBISBA)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Coordination and support actions
Countries involved: Spain,Germany,Italy,Germany,Spain,Italy,Greece,Belgium,Finland,France,France,France,Netherlands,United Kingdom
Call: Preparatory Phase of new ESFRI projects and early phase support to ESFRI high strategic potential areas (H2020-INFRADEV-2019-2, 2019)
Start date: 2020-01-01
End date: 2023-12-31
Duration (months): 48.0
Total project cost (EUR): 3995065.0
EU funding (EUR): 3995065.0
Participants: 20
Project status: SIGNED

EU-IBISBA is a distributed research infrastructure concept that will deliver translational research and innovation services to the research community and industry alike. Its aim is to accelerate the movement of knowledge and early stage research results towards maturity and uptake for further development by industrial R&I. EU-IBISBA's expertise is within the field of industrial biotechnology and focuses on the integrated development of bioprocesses, using a multidisciplinary approach and advanced technology such as synthetic biology. PREP-IBISBA intervenes just after the addition of EU-IBISBA on the ESFRI roadmap and as a follow-up to an ongoing H2020 INFRAIA starting community project entitled IBISBA 1.0. The aim of PREP-IBISBA is to create the conditions to launch EU-IBISBA. It will deliver all the conceptual elements necessary to finalize the science and technology case and define the business model, establish a long range financial plan and identify alternative legal frameworks suitable to deliver EU-IBISBA. Supported by strong managerial procedures, numerous stakeholders consultations, communication and dissemination work and specific actions aimed at delivering e-tools, this work will provide the basis for commitment by stakeholders, particularly Member States, but also industry investors (through a public-private partnership). Overall, the work will lead to the creation of a legal entity, preferentially either an ERIC or another suitable legal instrument. PREP-IBISBA will also prepare EU-IBISBA implementation by providing the opportunity for transition. Intervening after the creation of the legal entity, this involves the progressive initiation of EU-IBISBA business processes. Siting of EU-IBISBA will be decided, a skeleton Executive team put into place and preliminary governance deployed. The transition will allow dry running of some business processes and will ease EU-IBISBA towards full implementation.

Keywords: industrial biotechnology,synthetic biology,translational research,distributed ri,push pull innovation,public private partnership
Agroecological Transitions for Territorial Food Systems (ATTER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Italy,Italy,Italy,France,France,France,France,United States,United Kingdom,Brazil,United Kingdom,United Kingdom
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2020, 2020)
Start date: 2021-05-01
End date: 2025-04-30
Duration (months): 48.0
Total project cost (EUR): 1223600.0
EU funding (EUR): 1030400.0
Participants: 19
Project status: SIGNED

The ecological and social unsustainability of our food systems is widely acknowledged by scientists, citizens and governments around the world. To address the challenge of sustainable transitions, agroecology is also increasingly recognised as a promising model and the territorial scale as an appropriate scale of analysis and action. ATTER will develop an interdisciplinary and multi-sectoral exchange program to help filling the lack of knowledge and methodology for scaling out agroecological transitions for territorial food systems. It will gather researchers and practitioners around cross-case studies work through secondments, trainings and workshops, relying on the specificities of the five countries under study (France, Italy, UK, Brazil and USA) and on the complementary expertise and skills of the 18 participating organisations (10 academic and 8 non-academic). We will manage the ATTER network as an action-research eco-system to boost the emergence and dissemination of knowledge, innovations and tools for the agrifood systems’ transitions. The specific objectives of ATTER are to i) build a portfolio of 15 regionally embedded case studies representing diverse agroecological transitions and trajectories and transform this portfolio into a lasting observatory; ii) based on this portfolio, elaborate a typology of transition pathways in diverse contexts; iii) develop evaluation approaches and tools aimed at integrating the different dimensions involved in agrifood transitions; iv) analyse the effects of policy instruments and facilitating approaches and define policy recommendations and context-sensitive methodological frameworks aimed at facilitating these transitions; v) develop a diversity of adapted training and exchange activities both for academics and practitioners, which will allow more than 100 staff members to develop new skills, discover new research environments and expand their career perspectives, as well as to consolidate a wider and lasting network.

Keywords: food systems,agroecological transitions,territorial dynamics,action research