Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Soft Milli-robots (SOMIRO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Spain,Italy,Italy,Italy,Switzerland,Sweden,Sweden
Call: Research and Innovation boosting promising robotics applications (H2020-ICT-2020-2, 2020)
Start date: 2021-01-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 2992200.0
EU funding (EUR): 2992200.0
Participants: 9
Project status: SIGNED

SOMIRO Precision agriculture for rice farming and smart methods such as aquaponics are vital to ensure a safe supply of fresh food for Europe while reducing our environmental footprint. In line with the Digitising European Industry initiative under their description of smart agriculture, the SOMIRO project will develop a flat-worm-inspired mm-scale swimming robot with month-long energy autonomy, local intelligence, and ability to continuously generate data and optically communicate to reduce farming’s environmental impact in terms of carbon footprint, over fertilization, pesticide use, and overfeeding. Swimming robots would cover a much larger area than stationary systems and could be rapidly deployed and self-redistribute where most needed. They may serve as a stand-alone monitoring solution for indoor farming or complement drone-based remote sensing in outdoors scenarios. Until today, no energy autonomous (untethered and with local intelligence) milli-robot capable of hours of continuous operation has been demonstrated. The major reason for this is power limitation: locomotion requires much power and small robots have very limited energy storage and energy harvesting. Our milli-robot will be less than 1 cm long and show how soft and stretchable systems, with undulating swimming like flat worms, require far less energy for locomotion than other systems of comparable size. For power, it will not rely on any dedicated infrastructure but only on ambient light. The design of SOMIRO focuses on its industry transfer: industrial partners will use cutting-edge assembly technologies that can scale up to production volumes with no change in process. The bulk materials are low-cost elastomers and polymers and the electronic circuits will be based on commercial components. Throughout the project, all application scenarios and exploitation plans will be developed in close collaboration among the SOMIRO partner enterprises and end-users, and external industrial stakeholders.

Keywords: milli robot,soft robotics,soft actuator,travelling wave locomotion,visual light communication,nano mos,dielectric actuator,thin film solar cell,ultralightweight,precision agriculture
Adaptive Bio-electronics for Chronic Cardiorespiratory Disease (CResPace)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Emerging themes and communities
Action type: Research and Innovation actions
Countries involved: Austria,Switzerland,Czechia,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: FET Proactive: emerging themes and communities (FETPROACT-2016, 2016)
Start date: 2017-01-01
End date: 2022-12-31
Duration (months): 72.0
Total project cost (EUR): 4944347.5
EU funding (EUR): 4944347.5
Participants: 8
Project status: SIGNED

This consortium will pioneer disruptive technology for bio-electronic medicine to provide much needed therapies for cardiorespiratory and functional neurological disease. The technology implements small neural networks known as central pattern generators (CPG) to deliver fit-and-forget bio-electronic implants that respond to physiological feedback in real time, are safer, simpler, non-invasive, and have autonomy exceeding the patient lifespan. Multichannel neurons will be made to compete on analogue chips to obtain flexible motor sequences underpinned by a wide parameter space. By building large scale nonlinear optimization tools and using them to assimilate electrophysiological data, we will develop a method for automatically finding the network parameters that accurately reproduce biological motor sequences and their adaptation to multiple physiological inputs. In this way, we will have resolved the issue of programming analogue CPGs which has long been the obstacle to using neural chips in medicine. An adaptive pacemaker will be constructed, tested, validated and trialled on animal models of atrio-ventricular block and left bundle branch block to demonstrate the benefits of heart rate adaptation, beat-to-beat cardiac resynchronization and respiratory sinus arrhythmia. By providing novel therapy for arrhythmias, heart failure and their comorbidities such as sleep apnoea and hypertension, CResPace will extend patients’ life and increase quality of life.

Keywords: central pattern generator,large scale nonlinear optimization,cardio respiratory disease,adaptive electronics
Internal Dynamics and Magnetic field generation in rocky bodies: planets and large moons in the solar system (InDyMag)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-03-13
End date: 2021-09-14
Duration (months): 24.0
Total project cost (EUR): 185076.0
EU funding (EUR): 185076.0
Participants: 1
Project status: CLOSED

The Earth is a peculiar planet in the solar system: it hosts life and possesses a very active interior. However, it is not the only rocky body to present evidence of internal dynamics: all the rocky planets - except Venus - and some moons have been proved to generate or to have generated a magnetic field. Recent space missions have improved our knowledge of the evolution of these magnetic fields, and direct constraints on the internal structure of some rocky planets are expected in the very next few years. New hypotheses emerged recently to explain the early times of the Earth’s magnetic field, when no thermo-chemical convection could power the geodynamo, giving us new perspectives on Earth’s history. By combining advances in both Earth and planetary sciences, InDyMag aims to better understand the internal dynamics of the Earth and other rocky bodies in our solar system. It will investigate the generation and long-term evolution of their magnetic fields with Earth as a reference, and compare it Mercury, Venus, and Mars, and the Earth's Moon and Ganymede. The fellow, expert in geodynamics and modeling, will develop a model for the time evolution of temperature and composition profiles in metallic cores, exploring a large range of parameters including planet's size, composition and formation history. The crystallization regimes and the initial profiles will be investigated in detail, exploring the full range of dynamics possible in an iron core. Thanks to the expertise of the researchers at the host LPG on space missions and magnetic field measurements, InDyMag will combine observations to geodynamical models to constrain the physical parameters of planetary cores. InDyMag will unravel what is universal in planetary magnetic fields, and what is planet-specific. Its results will be disseminated to the general and specialist audience and will lay the foundations to explore planetary magnetic fields at the exoplanet level.

Keywords: core dynamics,magnetic field,rocky bodies,planets
Reliable urinary test for the diagnosis of prostate cancer (PROSTATOR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: France
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2020-02-01
End date: 2021-07-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Reliable urinary test for the diagnosis of prostate cancer Prostate cancer is a life threatening disease which affects about 400,000 males and causes 92,000 deaths per year in Europe. Among suspected cancer patients who undergo a prostate biopsy, only 45% really have a cancer. However, this diagnostic procedure is associated with discomfort, anxiety, bleeding, and the potential for serious infections requiring hospitalization. It is also very expensive. None of the tests available today offer an alternative which avoids unnecessary biopsies. To solve this problem we propose to validate a urinary, non-invasive, rapid and robust diagnostic test that we call PROSTATOR, for the early detection of prostate cancer without unnecessary biopsies. PROSTATOR quantifies three new prostate cancer specific biomarkers that we identified using our ERC Consolidator Grant. We show that, contrary to the biomarkers quantified by commercialized urinary tests for prostate cancer, our three new biomarkers were detected in all grades of tumours. Only cancer patients detected by our test will have a biopsy to determine the type and the grade of the prostate tumour but unnecessary biopsies will be avoided when the test is negative. Other advantages of our novel test: it can be performed from the first visit to the urologist, collecting the urine after prostatic massage and sending it to a laboratory that will give the diagnosis within 4 days. With this grant, we want to validate our first results on a large number of urines (900). We have established collaborations with Henri-Mondor and Foch hospitals to collect the urines and with the Genomic Platform of Institut Curie to quantify our biomarkers. We started discussions with tech transfer office of the Institut Curie to discuss the opportunity to license PROSTATOR to pharmaceutical companies that already confirmed their interest of our product, or create a start-up.

Keywords: diagnosis,urine,fluid,new biomarkers,prostate cancer
Establishing services enhancing the innovation management capacity of SMEs by the Enterprise Europe Network in North Rhine-Westphalia, Germany, in 2020-21 (Innovation.NRW)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Germany,Germany
Call: H2020 ENTREPRISE EUROPE NETWORK SGA4 2020-2021 (H2020-EEN-SGA4-2020-2021, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 592900.0
EU funding (EUR): 592900.0
Participants: 3
Project status: CLOSED

Innovations and thus also the management of innovations are of great significance for the competitiveness of the European Union, its Member States and their regions. Innovative individuals or enterprises do something which cannot be expected from the state of the art. They put innovations into practice – generally in the face of considerable resistance – and take financial, technical as well as social risks. Only in this way, however, can new technologies, processes, products or services assert themselves and future markets evolve. Employment, prosperity and the general quality of life and of the environment are directly dependent on the innovation capacity of regions and enterprises. Due to this interrelationship, the European Commission has promoted the Enterprise Europe Network since 2008 in order to provide local support above all to SMEs in the areas of internationalization, technology transfer and generally in the realization of innovations. One of the Network’s tasks is to raise the effectiveness and efficiency of innovation management in SMEs in order to accelerate the implementation of economically impactful innovations. Supporting SMEs in the area of innovation is a core task and the mission of ZENIT, coordinator of NRW.Europa, the Enterprise Europe Network node in North Rhine-Westphalia in the project Innovation.NRW. Whilst innovations naturally cannot be forecasted, they can, however, evolve under the right conditions and be successfully managed. Our understanding of innovation and innovation management is oriented at business opportunities. As a consequence, ZENIT is pursuing the different objectives in the Innovation.NRW project to maintain and expand the innovation capacity and competitiveness of the participating SMEs. In addition, ZENIT supports the beneficiaries of the EIC Pilot from NRW in the Innovation.NRW project.

Keywords: eimc,innovation,management,zenit,client journey,spoke,impact,network,nrw europa
Writing Jewish History: Ancient Judaism as a Political Problem in Central Europe at the Rise of the Nation State (AJAPP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-01
End date: 2019-08-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

AJAPP investigates the integration of religious minorities amid the rise of nation-states in Central Europe in the late modern period. Specifically, AJAPP focuses on political representation of ancient Judaism by Catholics, Jews, and Protestants throughout Prussia, Austria, and Bavaria in the course of the 19th century. The goal is to understand how portraits of the past reflected both the concerns and the conditions of modern times and, in turn, how these portraits impacted contemorary debates on issues of national, cultural, religious, and ethnic identity. It analyses how political and social differences - as opposed to strictly ethnic or cultural ones - as well as subtle prejudices manifested themselves in discussions of the past, how boundaries were made within a shared tradition, and how identities were configured in regional and national entities. This period is especially imortant as this was a time when distinct regions were negotiating their political relationships to one another (often with violence), when public discourse was debating which communities had which stakes in and rights to the political realm, and when the past became especially contested territory for determining which groups were insiders and which ones were outsiders. Given the current rise in regionalism, nationalism, and right-wing extremism across Europe, AJAPP addresses a central problem palpable on the local, international, and global levels today. It reveals how implicit assumptions inscribe the conceptualisation of the past, which then find their way back into the present.

Keywords: historiography,intellectual history,history of scholarship,institutional history,reception history,antiquity,modernity,judaism,protestantism,catholocism,19th century,modern europe
Understanding the molecular basis of stochastic bi-stable obesity (EPOC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-12-01
End date: 2018-11-30
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

Substantial evidence indicates that even when genetically matched, we are not created equal. The mechanisms underlying such non-Mendelian phenotype variation are sufficient to elicit complex disease but remain unknown. In this context, the regulators of chromatin state have the ability to establish cellular memory, which is encoding specific silenced gene expression states through mitosis and is involved in control phenotypic variation. Interestingly, two chromatin ‘stabilizing’ genes (Trim28 / Dnmt3a) and two obesity buffering ‘effector’ genes (Peg3 / Nnat) are involved in triggering bi-stable epigenetic obesity. This present proposal aims at intersecting all four models of polyphenism to identify the core transcriptional and chromatin machinery required to establish and switch ‘On’ or ‘Off’ the Obese state. Thus, I will to explore these four mutants [Trim28(D9/+), Dnmt3a(+/-), Peg3(+/-p), and Nnat(+/-p)], which will serve as a biological filter to reveal core requirements. First, I will define co-variation of a spectrum of complex trait phenotypes resulting from insufficiency at each of these loci. Then, I will decipher the mechanism underlying their sensitized bi-stable obesity. Third, I will assess the epigenetic basis of their buffering of polyphenism. The aim of this proposal is to precisely provide, for the first time, reference-depth phenomic and epigenomic profiling of chromatin sensitizer- (Trim28- / Dnmt3a-) and chromatin effector- (Peg3- / Nnat-) induced stochastic obesity. The work will uncover the first definitive genetic and genomic templates for probing non-Mendelian phenotypic variation and stochastic obesity and thus highlight new therapeutic perspectives.

Keywords: stochastic disease,obesity,metabolism,chromatin,epigenetic programming,suvar s genes,trim28,dmnt3a,peg3,nnat
Nano-Ridge Engineering for Densely Integrated III-V Lasers Directly Grown on Silicon (NARIoS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Belgium
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2020-09-01
End date: 2025-08-31
Duration (months): 60.0
Total project cost (EUR): 2482750.0
EU funding (EUR): 2482750.0
Participants: 1
Project status: SIGNED

Although Silicon Photonics, i.e. using mature technologies from the CMOS-industry for realizing complex photonic ICs, progressed enormously, with industrial uptake by the biggest electronics manufactures, its real breakthrough, in e.g. large volume consumer applications or very short interconnects, is hampered by its lack of a true waferscale optical source. Combining aspect-ratio trapping, to suppress defects, and nano-ridge engineering, to shape the resulting material, we have developed a powerful platform to integrate direct bandgap III-V semiconductors on standard silicon wafers, using truly waferscale processes. The exceptionally high quality of this material was confirmed through morphological studies, gain and lifetime measurements and the demonstration of lasing under optical pumping. For practical applications, electrical injection is key though, which thus far has been elusive as the dimensions of the resulting GaAs/InGaAs nano-ridges are too small to directly apply electrical contacts without introducing unacceptable losses. Therefore, NARIoS' primary objective is to propose device concepts that overcome the trade-off between optical confinement and efficient current injection. We aim at the demonstration of electrically injected microcavity lasers for low-power applications and the demonstration of a novel class of mW-lasers with in-plane or out-of-plane emission, exploiting the possibility to grow highly uniform arrays of these nano-ridges. Next, we aim to demonstrate single photon emission from long-wavelength InAs-quantum dots grown on the nano-ridge platform, eventually integrated in a suitable microcavity. These device-oriented objectives will be complemented by two transversal objectives: development and extensive characterisation of InGaAs nano-ridges for extending the lasing wavelength and exploiting novel concepts from recent literature to design lasers resilient to optical feedback and/or exhibiting lasing in a single coherent spatial mode.
Trapped-ion quantum information in 2-dimensional Penning trap arrays (IONPEN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Switzerland
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-04-01
End date: 2024-03-31
Duration (months): 60.0
Total project cost (EUR): 1999375.0
EU funding (EUR): 1999375.0
Participants: 1
Project status: SIGNED

This project will develop a new platform for quantum computation and quantum simulation based on scalable two-dimensional arrays of ions in micro-fabricated Penning traps. It builds upon the rapid advances demonstrating high precision quantum control in micro-fabricated radio-frequency ion traps while eliminating the most problematic element - the radio-frequency potential - using a uniform magnetic field. This offers a significant advantage: since the magnetic field is uniform it provides confinement at any position for which a suitable static quadrupole can be generated. By contrast, r.f. potentials only provide good working conditions along a line. This changed perspective provides access to dense two-dimensional strongly interacting ion lattices, with the possibility to re-configure these lattices in real time. By combining closely-spaced static two-dimensional ion arrays with standard laser control methods, the project will demonstrate previously inaccessible many-body interacting spin Hamiltonians at ion numbers which are out of the reach of classical computers, providing a scalable quantum simulator with the potential to provide new insights into the links between microscopic physics and emergent behavior. Through dynamic control of electrode voltages, reconfigurable two-dimensional arrays will be used to realize a scalable quantum computing architecture, which will be benchmarked through landmark experiments on measurement-based quantum computation and high error-threshold surface codes which are natural to this configuration. Realizing multi-dimensional connectivity between qubits is a major problem facing a number of leading quantum computing architectures including trapped ions. By solving this problem, the proposed project will pave the way to large-scale universal quantum computing with impacts from fundamental physics through to chemistry, materials science and cryptography.