Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Assessing and Monitoring the Impacts of Genetically modified plants on Agro-ecosystems (AMIGA)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Life sciences, biotechnology and biochemistry for sustainable non-food products and processes
Action type: Collaborative project
Countries involved: Italy,Denmark,Bulgaria,Austria,France,Finland,Spain,France,Belgium,United Kingdom,Romania,United Kingdom,Ireland,Germany,Netherlands,Germany,Slovakia,Sweden,Argentina,Germany
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2011-12-01
End date: 2016-05-31
Duration (months): 54.0
Total project cost (EUR): 7794852.79
EU funding (EUR): 5997963.0
Participants: 22
Project status: CLOSED

The project aims at 1 providing baseline data on biodiversity in agro-ecosystems in the EU, 2 translating regional protection goals in measurable assessment endpoints, 3 defining lists of suitable bioindicators for various European regions, 4 improving knowledge on potential long term environmental effects of genetically modified plants (GMPs), 5 testing the efficacy of the EFSA Guidance Document (GD) for the Environmental Risk Assessment (ERA) of GMPs, 6 exploring new strategies for post market monitoring, 7 estimating the compatibility of GMPs with the Integrated Pest Management (IPM) principles implemented in the EU, 8 providing a systematic analysis of economical aspects of GMPs cultivation in the EU, and 9 setting a training and communication plan addressing public concerns about GMPs. The consortium includes 22 partners (Research institutes, Universities, State Agencies and SMEs) located in 15 EU countries and. An ICPC country (Argentina) will contribute in validating the monitoring methodology in areas where GM crops are cultivated on larger scales. A cornerstone is the application of the EFSA ERA GD, which is the basis for the update of the regulatory process of GMPs in the EU. The GD has provided ecologically sound principles for ERA, triggering the need of practically testing them. Partners of the consortium participated to the preparation of GD and 3 of them are senior authors of relevant chapters. The scientific activities will consist of case studies of maize and potato, the two GM crops currently approved for cultivation in the EU, and surveys in non-GM agro-ecosystems. The final outcome will include a network of EU representative sites for pre-market risk assessment and long-term monitoring studies, a set of standardised testing methods and a geographical information system integrating relevant datasets, protocols and tools to help EU decision-makers. To be implemented in 4 years, the project estimated costs are 7779852.15 €, requested grant 5997963 €.

Keywords: genetically modified plants,receiving environment,environmental impact,economic impact,long-term effects,non-target orgnisms,post-market environmental monitoring,statistical approach
Stromal Cell- Immune Cell Interactions in Health and Disease (STROMA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Netherlands,Netherlands,United Kingdom,Switzerland,France,Germany,Austria,France,Portugal,Germany
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 4296181.91
EU funding (EUR): 4296181.91
Participants: 12
Project status: CLOSED

STROMA is an Initial Training Network promoting the study of stromal cell – immune system interactions during stroma development and function in health and disease. In STROMA we have bought together world leading experts from academia and industry in Europe to address the key scientific questions in this emerging field. STROMA will promote the training of three Experienced Researchers (ER) and seventeen Early Stage Researchers (ESR) combining research and training in state-of-the-art multidisciplinary technologies. Through “hands on” and a “Virtual Learning Environment” STROMA will train the ESRs in the latest imaging, animal models, genomics, infectious biology and stromal biology technologies in collaboration with our industrial partners. STROMA will provide training in communications skills, ethics, plagiarism, grant writing, intellectual property rights, industrial skills training, project management, entrepreneurship, research policy, commercial exploitation of results and public engagement and develop a Personal Training Plan for each ESR and ER. Through network meetings and localized training the ESRs will receive additional training in complementary skills. STROMA is a highly interconnected network with each ER/ESR project involving multiple collaborations and secondments with other network participants including an extensive placement with our industrial partners. The importance of stromal cells and the molecular mechanism of stromal cell function in the regulation of immune responses have only recently been appreciated and are an exciting new area in immunology. The purpose of STROMA is to ensure that Europe retains global leadership in this emerging field and translates basic research on stroma-immune cell interactions to novel products and technologies for European industry.

Keywords: health sciences,immunology,stromal biology,imaging,infectious disease,lymphoma,tissue engineering,development,immuno-therapeutics
Replication and Adaptation in Molecular Networks (READ)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,Israel,France,Germany,United Kingdom,Italy,Switzerland,United Kingdom,France,Germany
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 3036050.57
EU funding (EUR): 3036050.57
Participants: 10
Project status: CLOSED

Systems Chemistry (the chemistry of complex mixtures of interacting molecules) is a rapidly developing new fronteir in the chemical sciences. Where chemistry has for centuries been a firmly reductionistic science, Systems Chemistry breaks with this tradition by focussing on complexity and emergent behaviour. This network brings together nearly all major academic players active in Europe on experimental approaches to Systems Chemistry in general and molecular networks in particular. Our consortium is of exceptional quality and is a balanced mix of highly experienced scientists with mutiple publications in Science and/or Nature and talented young scientists of whom four have recently been awarded prestigious ERC starting grants. We have two full partners from industry that provide essential analytical support and the perspective on commercialisation of complex chemical systems. Aim of our high-level consortium is to provide a comprehensive high-quality training program on Systems Chemistry, in the context of a cutting-edge and wide-ranging research program, focusing on two important phenomena: adaptation and replication in molecular networks. These subjects will be developed towards application in enantioselective organoautocatalysis, molecular Boolean logic protocols, self-synthesising materials that exhibit electronic conductivity and adaptive biological functionality, sensing of bio-analytes, assessing molecular similarity and materials for anti-counterfeiting. Our comprehensive training and research program will deliver a new generation of young researchers eager to push the frontiers of the rapidly emerging field of Systems Chemistry, expanding Europe’s lead in this exciting new area.

Keywords: systems chemistry,dynamic combinatorial chemistry,autocatalysis,self-assembled materials,molecular networks,self-replication,sensing,origin of life
Retailer and Consumer Acceptance of Promising Novel Technologies and Collaborative Innovation Management (RECAPT)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Fork to farm: Food (including seafood), health and well being
Action type: Coordination and support actions
Countries involved: Denmark,Germany,Netherlands,United Kingdom,Netherlands,Belgium,Germany,United Kingdom
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2011-12-01
End date: 2014-11-30
Duration (months): 36.0
Total project cost (EUR): 1082132.92
EU funding (EUR): 998762.0
Participants: 9
Project status: CLOSED

There is an increasing recognition that innovation is a task for all actors in the food chain, since innovation should add value to the food chain as a whole and lead to sustainable novel applications. RECAPT aims at supporting a process that leads to closer collaborative management of innovations along the food supply chain. The overall objective of this action is to build a platform that strengthens collaboration between food scientists, food industry and the retailing and catering sectors, such that research findings can be effectively integrated into the development of innovative and sustainable products that meet consumer acceptance, thereby contributing to global competitiveness of the European food sector. More specifically, RECAPT has the following strategic objectives: 1. To promote information exchange and facilitate trust building in order to enhance innovation-oriented cooperation among the actors in the food supply chain. 2. To analyze all parameters and provide all necessary inputs for the realization and viability of those collaborations. In order to promote information exchange, facilitate trust building and enhance cooperation among actors in the food chain, a Collaborative Food Innovation Forum (CFIF) for effective dialog and collaboration between the food chain actors will be created. The CFIF will be a unique meeting place that will bring together actors from science, food manufacturing, retailing, catering and consumer organisations. Based on input from the different work packages, the CFIF will discuss issues related to promising novel technologies, consumer acceptance of new products based on novel technologies, retailer and caterer adoption of new products as well as innovation management processes in the food chain based on input from the RECAPT partners. In this way, a comprehensive view of the parameters and inputs necessary for increasing collaborative innovation activities in the European food sector will be developed.

Keywords: collaborative innovation management,consumer acceptance of novel technologies,new product development,retailing,catering,food industry,value chain,novel technologies
Improvement of comprehensive bio-waste transformation and nutrient recovery treatment processes for production of combined natural products (REFERTIL)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Collaborative project
Countries involved: Hungary,Netherlands,Denmark,Italy,Germany,United Kingdom,Spain,Poland,Slovenia,Ireland,Hungary
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2011-10-01
End date: 2015-09-30
Duration (months): 48.0
Total project cost (EUR): 4157112.2
EU funding (EUR): 2992935.0
Participants: 15
Project status: CLOSED

The objective driven goal of this SME targeted project is to improve the currently used compost and biochar treatment systems, towards advanced, efficient and comprehensive bio-waste treatment and nutrient recovery process with zero emission performance. The improved output products are safe, economical, ecological and standardized compost and bio-char combined natural fertilizers and soil amendment agricultural products used by farmers. The added value and energy efficient transformation of urban organic waste, farm organic residues and food industrial by-product streams made by improved carbonization, biotechnological formulation and upgraded composting technologies, with particular attention to the recovery of nutrients, such as phosphorous and nitrogen. The targeted high quality output products aiming to reduce mineral fertilizers and intensive chemicals use in agriculture; enhancing the environmental, ecological and economical sustainability of food crop production; reducing the negative footprint of the cities and overall contributing to climate change mitigation. In this context the improved bio-waste treatment process opens new technical, economical, environmental and social improvement opportunities, while improving the use, effectiveness and safety of the resulting compost and bio-char products in agriculture. The output products developed in a standardized way to meet all industrial, agricultural and environmental norms and stands in European dimension. Proactive and coherently integrated cooperation made between multi level stakeholder in Europe, with result oriented potential benefit to SMEs and farmers for more efficient utilization of the final products by the end-users. The project is providing strong support for policy makers for the revision of relevant policies, while setting up future common bio-waste recycling targets, common quality standard requirements for bio-waste treatment, compost and bio-char quality and trading requirements.

Keywords: nutrient recycling,natural phosphorus fertiliser,recycled nitrogen,organicwaste,animal by-products,biochar,compost
Innovation through human factors in risk analysis and management (INNHF)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy,Ireland,Serbia,Italy,Italy,Ireland
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2011-12-01
End date: 2015-11-30
Duration (months): 48.0
Total project cost (EUR): 3627721.01
EU funding (EUR): 3627721.01
Participants: 9
Project status: CLOSED

The aims of InnHF project are to offer a multidisciplinary training in the field of risk assessment and maintenance management integrated with human factors, in tight contact with companies and universities within this consortium; to strengthen and structure initial training of researchers in system engineering at European level; to attract students to scientific careers; to provide trained researchers with the necessary skills to work in industry; and to improve career perspectives by broad skills development. The INNHF scientific main objective is thus to formalize an approach and make it possible to integrate the current and developing assessment methods recommended or required by recognized industrial standards and methodologies, with an easy to use but complete human factors and system health management approach, the following goals will be achieved: 1) Review of the applicability of most recent generation standards that are not yet fully acquired by different industries and verification of their effectiveness in safety assessment. 2) Devising a method to account qualitatively and quantitatively for the human factor in the wider applied risk assessment methodologies. Verifying how a proper account of the impact of human and organizational factors (H&OF) in the operational phase may provide a sensitive change in the results of the assessments. 3) Reviewing the methods to account qualitatively and quantitatively for maintenance effectiveness, taking also into account HOFs, verifying how a proper account of the maintenance strategy may provide a sensitive change in the results of the assessments. 4) To translate the results of the analysis performed through the novel approach in a factual design improvement initiative for new or existing plant or machinery able to provide leverage for competitive advantage (maximum availability, minimum unscheduled shutdowns of production, economic maintenance, minimum incident incident and accident).

Keywords: manufacturing engineering,human & organisational factors,risk assessment,maintenance
BIOCERAMICS FOR BONE REPAIR (BIOBONE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Spain,France,Germany,Switzerland,Belgium,Germany,United Kingdom
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-03-01
End date: 2016-02-29
Duration (months): 48.0
Total project cost (EUR): 3691022.0
EU funding (EUR): 3691022.0
Participants: 9
Project status: CLOSED

There is a general consensus that ceramic based materials should play a very important role in the development of new therapies to treat and substitute damaged or diseased bone. Due to their resistance to wear and corrosion, bioinert technical ceramics are the ideal candidates to replace metallic alloys in a new generation of small, durable and safe orthopaedic implants. On the other hand, osteoconductive and bioactive ceramics such as calcium phosphates and bioactive glasses are the most promising materials to fabricate strong scaffolds to support the engineering of new bone. Ceramic implants and scaffolds are already being introduced in the market and its application is growing. However, for ceramics to fulfil their promise it will be necessary to address several key scientific issues such as the development of toughness and resistance to fatigue in the physiological media, the need to achieve strength in porous tissue engineering scaffolds or the control bioresorption and the interactions at the cell/material interface. To solve these issues a new generation of professionals is needed with a solid multidisciplinary background that will incorporate fields as diverse as materials science and engineering, orthopaedics, tissue engineering, biology, chemistry and biomedical engineering. The final objective of this network is to train young researchers to fill this demand in the strategic area of bioceramics for bone repair. BIOBONE will achieve this by combining hands-on training in state of the art research projects related to key fundamental issues that determine the future bioceramics with academic training and industrial experience. The goal is to form professionals that will play a pivotal role in pushing forward this growing, highly competitive, knowledge-intense field for the coming decades benefiting the European economy, bringing state-of-the-art technology to the bedside and improving the quality of life and current standards of care

Keywords: biomaterial engineering,materials engineering
Developing single cell technologies for systems biology (ISOLATE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Sweden,Netherlands,Switzerland,United Kingdom,Denmark,United Kingdom,Czechia
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 2994929.01
EU funding (EUR): 2994929.01
Participants: 8
Project status: CLOSED

Biological cells are entities with highly complex, non-linear control circuits. They can thus express intricate behavior, such as stochasticity-induced multistability, oscillations, responses at different time scales, hysteretic behavior, memory, etc. Biology is only about to start to investigate these phenomena, which all occur at single cell level and often result in phenotypic heterogeneity. It is required to experimentally probe single cells, as population-level analyses will mask most of the behaviors of individual cells. Development of single cell measurement techniques represents an area for exciting research and development, being the key enabling technique to ultimately understand important complex biological behaviors. The education of highly qualified specialists with multidisciplinary skills is a pivotal prerequisite for addressing these biological problems and, even more importantly, for transferring this knowledge into marketable products. This proposal seeks funding for a truly interdisciplinary European consortium to train researchers to develop and exploit novel technologies for single-cell analysis in the context of system-level metabolic cell behavior. The crucial importance of single cell analysis has been stressed in a recent Science News Focus and the area of metabolism was highlighted in Nature’s “New year, new science" outlook for 2011. ISOLATE represents an Initial Training Network involving eleven trainees. A range of methodologies will be included to provide unique training to fellows in single cell analyses and to investigate complex phenomena. A high degree of multidisciplinarity and the inclusion of key industrial stakeholders make ISOLATE especially suitable for a training program ranging from forefront microtechnology, bioengineering, biophysics, via analytical chemistry to biochemistry and systems biology.

Keywords: biomedical engineering,microengineering,biochemical technology,medical instrumentation,bioassays,measurement technology,cell biology,computational biology,metabolism,instrumental techniques
Adaptive Brain Computations (ABC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Netherlands,Italy,Belgium,Netherlands,United Kingdom,Germany,Germany,United Kingdom,Germany
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-06-01
End date: 2016-05-31
Duration (months): 48.0
Total project cost (EUR): 3805430.96
EU funding (EUR): 3805430.96
Participants: 10
Project status: CLOSED

Adaptive interactions with the environment depend on sophisticated brain plasticity mechanisms at multiple levels: from single neurons to large-scale brain networks. Traditionally, the study of plasticity has been fragmented into sensory, motor or decision-related circuits. However, translating brain plasticity findings to brain repair requires an understanding of the interactions between these circuits. Our aim is to integrate this study of learning and plasticity to promote wellbeing and advance healthcare interventions. We take a multidisciplinary approach, synthesising methods from physiology, cellular neurobiology, pharmacology, brain imaging, behavioural science and computational modelling to reveal plasticity at multiple scales (cellular, structural and functional). We will test how learning modifies sensory representations, perceptual decisions and motor outputs. Further, we will examine brain reorganisation and long-term plasticity in cases of congenital or acquired sensory and motor deficits. Our approach requires the coordinated efforts of international research leaders who work in top Universities and market-leading companies. This research training environment will deliver a cohort of young researchers experienced in transcending traditional disciplinary boundaries to deliver deeper insight into brain plasticity. Further, ABC’s approach of cementing interactions between sectors into the training programme means that our ESRs will have the skills necessary to move between sectors and can maximise the translation of their findings for human health and wellbeing. The work has impact in assistive technology, education and rehabilitation and expert recognition systems. The involvement of private sector companies, and a pronounced focus on translational aspects within the network’s activities (i.e. at all training events), will enhance European capacities for brain plasticity research and its applications.

Keywords: neurophysiology,neuropsychology,neuroinformatics,cognitive science,experimental psychology,health sciences,neurosciences,behavioural sciences