Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Data-driven, Integrated, Syncromodal, Collaborative and Optimised urban freight meta model for a new generation of urban logistics and planning with data sharing at European Living Labs (DISCO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Safe, Resilient Transport and Smart Mobility services for passengers and goods
Action type: Innovation actions
Countries involved: Italy,Germany,Greece,Spain,France,Netherlands,Belgium,Finland,Denmark,Czechia,Sweden
Call: Urban logistics and planning: anticipating urban freight generation and demand including digitalisation of urban freight (HORIZON-CL5-2022-D6-02, 2022)
Start date: 2023-05-01
End date: 2026-10-31
Duration (months): 42.0
Total project cost (EUR): 8873483.59
EU funding (EUR): 7999972.13
Participants: 49
Project status: SIGNED

DISCO will develop and demonstrate - in real-life conditions - a federated European urban freight (UF) data space as one stop shop of data sharing on digital urban logistics solutions and smart tools for ambitious decision making. It will be a continental Ten-T – oriented and distributed real-life ecosystem to prove its value via demonstrated and replicable Use Cases (UCs), build upon innovation drivers to code concrete transformation of urban planning and land use by an open and collaborative UF Data Space with a smart governance model. The DISCO UF Data Space is voluntary based (incentivized), co-created and open framework to achieve a radical transformation and alliance in purpose-oriented data sharing, enabling smart access, fast and resource efficient acquisition, and focused provision, improving knowledge and capacity of city authorities and planners guaranteeing future data availability for dynamic (and predictive) integrated urban logistics planning, synchronizing real-time demand for transport & warehousing with logistics supply, (e.g., as Uber matches the demand for private car transport service with its road drivers’ fleet). DISCO will support European urban logistics players in reducing economic, societal and technical dependence from private digital platforms owned by large global providers, magnifying the scope of a Sustainable Urban Mobility Plans (SUMPs) converging to data-driven Sustainable Urban Logistics Planning (SULPs), expanding them beyond traditional urban boundaries (e.g., rural areas, towns and suburbs, cities, and urban areas according to World Urbanization Prospects ) and beyond Covid-19, to optimally manage, monitor and dynamically predict city freight flows, changing urban nodes accessibility by properly serving Functional Urban Area - FUA on a larger, mixed-use, and flexible scale , and deliver advanced and well-informed planning and purpose oriented, optimised land use within a TEN-T and global dimension.

Keywords: urban logistics land use sustainable planning 12 pilot sites digital transition physical internet data space
RELatinG quALIties and quantities by resource Approximation (REGALIA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 1
Project status: CLOSED

Qualitative type systems are a widespread technique exploited in the study of programming languages. Types allow to obtain relevant information on the behaviours of programs, such as termination of the evaluation. Quantitative type systems are used to achieve additional information on complexity and resource consumption. While these two families of type systems have been deeply studied, their interaction is still far to be properly understood. Given a program typed in a qualitative way, can we extract quantitative information from it in a compositional manner? This very natural and fundamental question has not received any appropriate answer yet. REGALIA aims to answer the question, deepening our understanding of the relationship between these two kinds of type systems. In order to do so, REGALIA will further develop the theory of resource approximation, by extending Girard's approximation theorems to proofs with cuts and by establishing a translation algorithm between qualitative systems and quantitative ones. I shall then exploit these results to define modular methods to study programming languages, alternative to Tait-Girard reducibility, that will offer quantitative interpretation of relevant qualitative systems in the context of both pure and effectful computation.

Keywords: programming language theory,type systems,resource approximation,quantitative bounds
A Revolutionary Artificial Cornea and Surgical Procedure (RESEE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Israel
Call: Strategic Digital and Health Technologies (HORIZON-EIC-2021-ACCELERATORCHALLENGES-01, 2021)
Start date: 2022-02-01
End date: 2024-08-31
Duration (months): 31.0
Total project cost (EUR): 3484432.5
EU funding (EUR): 2422519.0
Participants: 1
Project status: CLOSED

The CorNeat KPro is a patent pending fully artificial cornea (no donor required) which provides a life-long solution for corneal blindness, pathology, and injury. Its novel approach, technology and surgical procedure bio-mechanically integrate artificial optics within resident ocular tissue. The CorNeat KPro wide aperture acrylic lens, identical in optical quality to the native non-astigmatic cornea, is surrounded by a non-degradable synthetic polymer skirt-like scaffold that mimics the native Extra-Cellular-Matrix and stimulates cellular growth and infiltration. The CorNeat KPro integrates underneath the conjunctiva, a site rich with fibroblasts, which heals vigorously. As a result, the CorNeat KPro skirt assimilates within the eyewall tissue providing a no follow-up life-long solution. CorNeat KPro and its implant procedure is 50% cheaper than traditional corneal implant hence an affordable remedy for millions of people with cornea-related visual impairments.

Keywords: cornea implant,artificial tissue printing,mechanical engineering,engineering and technology,safety,biocompatibility,clinical trials,medical device implant,blindness,keratoprosthesis,keratoplasty,electrospinning
Deep exploration BoostEd by Advanced exploration Technologies (DeepBEAT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Germany,Finland,Czechia,Canada,Hungary,United States,France
Call: Exploration of critical raw materials in deep land deposits (RIA) (HORIZON-CL4-2024-RESILIENCE-01, 2024)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 4886982.5
EU funding (EUR): 4886982.0
Participants: 11
Project status: SIGNED

The project consortium of DeepBEAT aims to develop ground-breaking technologies to use geochemistry for the detection of deep-seated land deposits. Transforming Europe's exploration sector by integrating cutting-edge technologies and sustainable practices will push Europe towards a climate-neutral and socially responsible economy. The exploration of deep land deposits should employ environmentally friendly, socially acceptable, and ultra-low impact methodologies to ensure the citizens that exploration activities can be conducted responsibly. Acceptance to exploration and mining will be a cornerstone towards cultivating a more resilient and inclusive European society. DeepBEAT final outcome will be a workflow which addresses these aspects by two means: I) DeepBEAT plans to engage with the local communities at the test sites to learn about concerns, hesitancy and what is the emotional core of these. Experiences from these events will be included in exploration workflow as an integral part, following the principles of free, prior, informed consent, which requires to interact with communities at a very early stage. II) DeepBEAT proposes ten novel technological developments, all designed to minimize impact on environment and maximise sustainability. These research and innovation developements have the potential to push the limits of surface geochemical exploration to an other level. They comprise a) new insights to ultra-high resolution analytical chemistry, b) increasing sampling strategy efficiency, c) introducing ground-breaking new concepts of dealing with elemental measurement data, d) reducing exploration costs by sample selection, e) testing novel phyto-geochemical media, and f) introducing UAV assisted biogeochemical sampling. Detailed understanding of the deposits complement the workflow to allow the understanding of the mineralizations as part of mineral systems and AI-assisted 3D mineral prospectivity modelling.

Keywords: geology,mineral systems,exploration,geochemistry,workflow,analytics
A comprehensive CAD system based on radiologic- and pathologic-image biomarkers for diagnosis and prognosis of breast cancer relapse (BosomShield)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Sweden,Netherlands,Italy,Slovenia,Germany,Malaysia,United States,France,Poland
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 2815002.51
EU funding (EUR): 2595355.2
Participants: 27
Project status: SIGNED

Breast cancer (BC) incidence in women produces more than 600,000 deaths each year. The primary cause of death in BC patients is metastasis, whereby cancer cells spread from their primary site of origin and grow in adjacent or distant sites. Distant metastasis produced due to the relapse of the illness is incurable, underscoring the inadequacy of our understanding of its mechanisms. The first step for fighting against disease progression is screening programs for BC focused on image analysis of mammography, MRI and tomosynthesis. Once the tumour has been diagnosed and given the high variability of clinical progressions, another problem arises: classifying the cancer type and determining the proper treatment for specific cancer. Moreover, in BC, the immune response from the tumour microenvironment has played an essential role in tumour evolution. To evaluate the tumour and its microenvironment, one technique garnered a lot of attention in the last years: Whole Slide Imaging (WSI). This technique replaces the use of the microscope for classical diagnosis. Still, it has also been used for developing biomarkers that allow the analysis of tumours and classification of cancer subtypes and the study of the immune tumour microenvironment. The use of WSI has applications for predicting the probability of relapse for distant metastasis. Now, for the first time, BosomShield proposes to join the two disciplines (pathological and radiological imaging) in a software that will analyze these images to classify the cancer subtypes and predict (together with the complete clinical history of the patient) the probability of relapse for distant metastasis. Besides, BosomShield will provide high-level training in BC research to young researchers by offering the necessary transferable skills for thriving careers underpinned using diverse disciplines, digital radiology and pathology, biomedical, AI, privacy and software development.

Keywords: breast cancer relapse biomarkers radiological imaging pathology imaging
Optical probing of charge traps in organic field-effect transistors (OPTOCHARGE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-05-01
End date: 2025-04-30
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: SIGNED

Organic electronics offers huge potential for fabrication of large-area, low-cost, and efficient devices. Solution processing and availability of a vast library of organic semiconductors enables to exquisitely tailor properties to each application, while minimising waste of materials and maintaining low temperatures during processing thus reducing energy use. Although organic electronic devices have reached the market in large and flexible displays, their real potential in biomedical applications, sensing, and sustainable electronics remains unrealised. Crucial fundamental building blocks, such as organic field-effect transistors, are still hindered by limited charge mobility and unpredictable outcomes with new material recipes. Organic semiconductor performance is significantly reduced by formation of charge traps, which are local defects in the material or interfaces that remove charge carriers from the device conduction channels and obstruct transport. Accurate control of charge traps is critical to boost device performance, but they are notoriously difficult to identify, characterise and rationally engineer. OPTOCHARGE adopts a novel approach to optically stimulate traps with high spatial, temporal, and energy resolution, and reveal the key parameters for charge trap optimisation. The project systematically explores crystallinity, morphology, material blends, dopants and electrolyte gating to dissect the origin of traps and offer effective strategies to boost device performance. The proposal leverages unique interdisciplinary synergies between applicant and host, and provides an outstanding research setting to fulfil the full potential of the applicant and launch his academic career.

Keywords: organic semiconductors,organic electronics,organic field effect transistors,charge transport,thin films,light matter interaction
Human Longevity: Why older individuals in poorer nations outlive those in wealthier nations (LONGEVOUS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1499942.0
EU funding (EUR): 1499942.0
Participants: 1
Project status: SIGNED

Individuals in poorer nations generally live shorter lives than their counterparts in wealthier nations. Paradoxically, as people age, an intriguing reversal of this pattern emerges, with older individuals in certain low- and middle-income countries (LMICs) outliving those in high-income countries (HICs). Why do older people in LMICs outlive those in HICs? Why does the later-life survival advantage only occur for some LMICs? Answering these pressing questions is critical for addressing the current and future impact of aging societies and for advancing theories of the mortality transition that do not yet consider the diversity of aging experiences worldwide. LONGEVOUS has three ambitious goals and bold theoretical thrusts: (A) to assess the theoretical framework that explains the paradoxical later-life survival advantage in LMICs, (B) to assess the empirical mechanism behind low mortality at older ages in LMICs, and (C) to investigate whether this unexpected mortality paradox also emerges in terms of health outcomes. Project A tests the theory that adverse conditions over the life course create a group of robust individuals in later life. Project B develops a novel method for estimating mortality at older ages in certain LMICs, where the poor quality of age data remains unresolved and prevents us from testing mortality theories. Project C adds the health component to better understand country disparities in mortality at older ages. LONGEVOUS not only opens new perspectives for longevity research but also represents an unprecedented effort to conduct the most comprehensive study to date of the factors that shape mortality at older ages in LMICs. LONGEVOUS will use a combination of several demographic and statistical methods, and multiple data sources, including censuses, record linkage studies, and longitudinal health data. The benefit of LONGEVOUS is clear: a ground-breaking paradigm shift in our understanding of later-life survival on a global scale.

Keywords: longevity ageing later life mortality global health mortality paradox
Efficient valorisation of CO2 and bio-waste for long-term energy storage using a microwave plasma torch and quenching using the reverse Boudouard reaction (EffiTorch)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Belgium,Denmark,Austria,Switzerland
Call: Next generation of renewable energy technologies (HORIZON-CL5-2024-D3-01, 2024)
Start date: 2024-10-01
End date: 2028-09-30
Duration (months): 48.0
Total project cost (EUR): 2980222.5
EU funding (EUR): 2980222.5
Participants: 9
Project status: SIGNED

Now that renewable energy generation is already competitive in cost with electricity obtained from fossil fuels, the development of efficient long term energy storage methods seems crucial for a faster transition to a net-zero greenhouse gas emissions EU economy. Power-to-X methods are promising due to their negligible discharge rate but up to now all the efforts have been based on the use of H2 obtained by electrolysis, and the TEAs have shown that the high cost of the electrolysers hinders greatly its possibilities of industrial use. EffiTorch aims at developing an alternative breakthrough technology for Power-to-X based on the direct splitting of CO2, using an ultra-high temperature thermal plasma, with the simultaneous valorisation of low value bio-waste, leading to the efficient production of syngas. EffiTorch aims to reach carbon efficiencies higher than 90% and energy efficiencies higher than 60%, outperforming the best solutions available presently. Some of the research groups in Effitorch have a vast experience in CO2 splitting using Microwave (MW) plasma torches. Nevertheless, recently a compound approach that combines CO2 splitting by thermal plasmas with a quenching using the very endothermic reverse Bouduard reaction (RBR) has been developed in China that vastly improves the promising results obtained in the splitting of CO2 , while solving one of the yet unresolved issues, that of the efficient separation of the gases obtained. EffiTorch aims to explore the possibilities offered by a much improved version of the experimental set-ups used by the Chinese groups, including additional sophistications like the ultrasonic atomization of a bio-oil obtained by Hydrothermal Liquefaction (HTL) from sewage sludge, the use of high temperature reactors with plasma confinement and the implementation of a secondary heating of the plasma by induction with HF frequency (100-400 KHz), that could improve the energy efficiency and reduce costs.

Keywords: energy storage,co2,bio waste,co2 valorisation,plasma,thermal plasma,hidrothermal liquefaction,pyrolytic oil,sewage sludge,induction heating,boudouard reaction,quenching
Addressing malnutrition and metabolic health in non-communicable diseases through precision Nutrition: impact in quality of life and prognosis of lung cancer patients. (MENTORING)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Spain,Germany,Portugal,Italy
Call: EIC Pathfinder Challenge: Precision Nutrition (HORIZON-EIC-2023-PATHFINDERCHALLENGES-01, 2023)
Start date: 2024-09-01
End date: 2028-08-31
Duration (months): 48.0
Total project cost (EUR): 4031666.25
EU funding (EUR): 4031666.25
Participants: 7
Project status: SIGNED

Malnutrition represents a major burden for a large part of the population and, in particular, for vulnerable population groups like lung cancer patients. Lung cancer is a global health crisis, with over 2.2 million new cases in 2020 and profound societal and economic impacts. Lung cancer patients suffer from reduced quality of life, psychological distress, comorbidities, and the challenges of frequent treatments, as well as malnutrition and metabolic complications. MENTORING seeks to enhance patients' nutritional and metabolic statuses by targeting deficiencies in macro- and micronutrients and restoring the microbiome and glycomic health profiles. This will contribute to improving the overall quality of life of lung cancer patients, increasing treatment efficacy, and potentially enhancing their survival rates. By combining dietary assessment, nutritional and clinical biomarkers, immune-inflammatory signatures, anthropometry, genetics, glycomics, lung and gut microbiome, and food-related metabolomics, we will develop holistic models able to predict individual responses to personalised dietary plans considering multiple nutritional and metabolic outcomes. This precision nutrition approach will play a critical role in lung cancer care by customising dietary guidance based on an individual's genetic makeup, nutritional assessment, and health status to reduce cancer progression and increase quality of life. This collaborative effort is tailored to the specific needs of Lung cancer patients, but it has been built in order to make it easily translatable to any other vulnerable population suffering from malnutrition or metabolic impairments. The ultimate goal of MENTORING is to enhance patients' nutritional and metabolic statuses by using validated multi-omics approaches, potentially transforming the healthcare landscape.

Keywords: precision nutrition,metabolic health,lung cancer,glycans,omics,mechanistic modelling,digital platform,dietary interventions,microbiome,immuno metabolic health