Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
STRATEGY TO INHIBIT TGF-Beta IN LIVER DISEASE (IT-LIVER)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,Italy,Netherlands,Austria,Sweden,Germany,Spain,Germany,Spain
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2016-09-30
Duration (months): 48.0
Total project cost (EUR): 3312185.0
EU funding (EUR): 3312185.0
Participants: 11
Project status: CLOSED

Chronic liver diseases (CLD) and their end-stages, cirrhosis and hepatocellular carcinoma (HCC), are leading causes of morbidity and mortality worldwide with enormous socio-economic costs. Patients with liver cirrhosis are at high risk of deadly hepatic failure and over 80% of HCC develop on a cirrhotic background. HCC ranks as the 5th most common cancer and with >600,000 deaths per annum it constitutes a major global health problem. The main etiologies of CLD are chronic HCV and HBV infections, alcohol abuse and nonalcoholic steatohepatitis (NASH) as a result of the metabolic syndrome taking epidemic proportions. Liver transplantation is currently the only available therapy for terminal liver failure. It is well recognized that the cytokine TGF-Beta plays a pivotal role in the sequence of events leading to end-stage CLD, but the complexity of the underlying aberrant responses in the cells and the organ that lead to the drastic changes seen in CLD and HCC is poorly understood. A broad spectrum of scientific and technological capacities is needed to accomplish the goal of discovering drugs and treatment modalities for CLD and HCC.As a result, there is a lack – in academia and industry alike - of internationally oriented researchers and research leaders, capable of seamless and bi-directional transfer of goal-oriented scientific knowledge and technologies between the basic, translational and clinical research and industrial capacities; a conditio sine qua non for effectively and efficiently combating CLD and HCC and alleviate its medical and socio-economic burdens. Consequently, the ITN formulated the mission to provide a multidisciplinary and intersectorial Research Training Programme for talented young researchers, so as to prepare them for leading roles in CLD research and drug discovery in European industry and academia.

Keywords: cancer and its biological basis,l307 cell signalling and cellular interactions,l703 pharmacology - toxicology - pharmacogenomics - drug therapy,l308 signal transduction
Researchers imagine the Future (RIF)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: France,France,France,France,France,France,France,France,France,France,France,France
Call:  (FP7-PEOPLE-2012-NIGHT, 2012)
Start date: 2012-05-01
End date: 2012-11-30
Duration (months): 7.0
Total project cost (EUR): 497022.7
EU funding (EUR): 180000.0
Participants: 12
Project status: CLOSED

Under the banner of EU 2020 innovation initiative, the Researchers' Night 2012 will be run in France around the theme: Imagine the Future. Over 15 sites across the country will allow nearly 20,000 visitors to meet and exchange with over 400 researchers working on a multidisciplinary range of scientific disciplines, ranging from Social Sciences to fundamental and applied sciences. The “RIF” project has been specifically designed to overcome the stereotype of researchers working alone in their laboratories without any further contact with the “real” world. By following a new and innovative way of discovering science through art and entertainment this project aims at enhancing public recognition of the researchers, their role in society and the importance of scientific research to the public day-to-day life. In a relaxed and friendly atmosphere, visitors will have the opportunity to express their feelings, and opinions about both the researchers’ work and their role in society. Reciprocally, researchers will have the opportunity to express their concerns about their work. Furthermore, as if they were in front of a crystal ball, participant researchers will be asked to imagine what the future will be like in 30 years. They will have to imagine the evolution of their research, and the effects it will be likely to have on the world and society.Special attention will be paid to young public, using an accessible language adapted for non scientists. Activities foreseen throughout the RIF’s project range from treasure hunting, face-to-face meeting, to the creation of a surprising universe of projected lights and lasers. RIF project proposes to discover how researchers imagine future societies and try to shape them, to discover talented junior’s researchers work and cutting-edge research. Researchers' Night 2012 will focus on the diversity and cross existing research, while putting out that Researchers are also ordinary people working for a better future for all of us.

Keywords: innovation,future,researchers,teenagers,pleasure,discovery,imagine,family,diversity,conviviality,experiences
The development of in silico process models for roll compaction (IPROCOM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany,Austria,France,Czechia,Romania,Poland,Germany
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 3816547.75
EU funding (EUR): 3816547.75
Participants: 10
Project status: CLOSED

Particulate materials, e.g. pharmaceutical formulations, precious metal, fine chemical, metal & ceramic powders, have been compacted to produce a wide range of particulate products in a number of industrial sectors. The diversity of particulate materials and the complexity of manufacturing processes make it a challenging task in product development and process design for particulate product manufacturing. In particular, their applications in manufacturing high value-added products (such as pharmaceuticals and catalysts) are constrained by a number of scientific and technology hurdles. IPROCOM will address these challenges in a timely manner by bringing together 4 leading European research groups from world-leading universities, 2 national research institutes, and 8 private partners (including 4 SMEs), through a coordinated research and training programme. Our vision is to develop robust in silico process models that can be used to predict the properties of intermediate (ribbons/granules) and final products (tablets/pellets/components) based on the properties of individual particles with identified optimal process conditions and formulations. This will be an innovative and economic tool for product developments, especially for high value-added products. The model will be developed through thorough process understanding and natural synergy of a range of advanced modelling techniques. Our vision will be realised through close collaborations among the partners involved in this truly multidisciplinary IPROCOM consortium, who specialise in complementary areas and possess a broad range of research infrastructures. This will be further enhanced by training a cohort of 12 ESRs and 3 ERs, who will be the next generation technology leaders with the necessary depth and breadth of experience combined with the research and transferable skills to work effectively across disciplinary and sectoral boundaries and competences in applying the in silico tools.

Keywords: g111 modelling tools,g316 production technology - process engineering
The Researchers Variety Show (VARIETY)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-NIGHT, 2012)
Start date: 2012-04-01
End date: 2012-10-31
Duration (months): 7.0
Total project cost (EUR): 80710.28
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

EU Researcher Night 2012 gives a unique opportunity to host a prestige community event in post Olympics East London, to coincide with the reopening of the refurbished Great Hall in the People’s Palace, reinforcing our institution’s historical roots and to helping signal the enhanced institutional commitment to research dissemination through the creation of our new academic Centre for Public Engagement. A day of events for all ages will culminate in a grand Variety Show extravaganza reinforcing that Queen Mary and her researchers are and will continue to be a part of the community. To achieve this our work in the lead-up to the night will be focused on preparing materials that will be available for attendees and, as importantly, for a much longer-term web-based audience. This approach allows us to embed both the information and web-based activities into a dedicated Public Engagement website which will be sustained beyond the event itself. Researchers’ night will be further enhanced by working with media partners Mile End Films and The Naked Scientist, two successful groups who use current media technologies such as webcast, podcasts and radio broadcasts to reach the general public. The Naked Scientists, reaches a potential audience of 6 million listeners across the East of England and has on average of 5 million downloads of their podcasts a year. Through these media groups we estimate an outreach potential of over one million people through our radio broadcast and post dissemination activities. In the long term we will build on the success of the event by nurturing the networks and connections stemming from this high profile EU event.

Keywords: researchers,variety show,science,technology,arts,humanities,social sciences,medicine,edutainment,circus
Intel-CERN European Doctorate Industrial Program (ICE-DIP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland,Ireland
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-02-01
End date: 2017-01-31
Duration (months): 48.0
Total project cost (EUR): 1249027.0
EU funding (EUR): 1249027.0
Participants: 3
Project status: CLOSED

ICE-DIP, the Intel-CERN European Doctorate Industrial Program, is an EID scheme hosted by CERN and Intel Labs Europe. ICE-DIP offers research training to 5 Early Stage Researchers (ESRs) in advanced Information and Communication Technologies (ICT). The technical goal of this program is to research and develop, through a public-private partnership, unparalleled capabilities in the domain of high throughput, low latency, online data acquisition. The interdisciplinary and interconnected research themes are the usage of many-core processors for data acquisition, future optical interconnect technologies, reconfigurable logic and data acquisition networks. These topics form a solid foundation for future cutting-edge data processing technologies of high interest to a broad range of industries. CERN, which has recently produced exciting hints of new physics with its Large Hadron Collider, is planning for future upgrades of its facilities. The research themes addressed by ICE-DIP are critical to the sustained forward momentum of European High Energy Physics and numerous other disciplines of science and technology. The results of this research will allow the partners to maintain technological leadership and produce significant transferable expertise which will be disseminated via the ESRs to the research and business communities. The unrivaled research experience and training resources of the partners guarantee a highest quality network for research and training. CERN and Intel Labs Europe have a track record of effective multidisciplinary and intersectoral actions. Academic rigour and training quality is ensured by the associate partners, National University of Ireland Maynooth and Dublin City University, where the ESRs will be enrolled in doctorate programmes. The network’s combined training program provides a unique environment for the ESRs to enhance their research potential, competitiveness and employment opportunities while accelerating European science.

Keywords: lhc,cern,daq
Research and Competence Training Network for Sustainability-Driven Innovation (I4S)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark,United Kingdom,Germany,United Kingdom,Netherlands,Netherlands,Belgium,South Africa,Belgium
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 2613228.46
EU funding (EUR): 2613228.46
Participants: 9
Project status: CLOSED

The EC is committed to a research and innovation policy that drives ‘smart, sustainable and inclusive growth’. The I4S training network is designed to study sustainability-driven innovation (SDI) in support of this objective. This is much needed as SDI is poorly understood, with companies only now experimenting with practice in this emerging field. This provides opportunity for a new program of research. Preliminary research and prospective studies suggest that SDI involves management competences and organisational capabilities rarely found in traditional business-led technology-driven innovation. SDI often begins with managerial innovation rather than technological innovation. It draws on new platforms of actors or a blend of social and business innovation. Models drawn from nature can be used as inspiration for innovation. It can lead to new business models that create and capture value, providing for performance in economic, environmental and social terms. The goal of the ITN is to research how companies manage the process of SDI. The aim is to provide research training for 9 early-stage researchers and 2 experienced researchers who will be equipped to share their knowledge as academic researchers and teachers. The ITN uses a binary approach to research training, based on collaboration between companies and academic partners so that new knowledge is academically rigorous and of practical relevance. Management practice will be studied by researchers embedded with associated partners engaged in innovation. This approach is essential if the researchers are to ground their research in this new, often experimental area of practice. The ITN is designed to develop generic knowledge about the barriers and obstacles to innovation across sectors. Associated partners will be encouraged to share knowledge, experiences and good practice. The programme is designed in line with the EC’s latest thinking on university-business partnerships and the valorisation of new knowledge.

Keywords: sustainability-driven innovation,strategy and management,new business models,inter-organisational processes,systems change,supra-disciplinary,action research,case studies
Polymer - Carbon Nanotubes Active Systems for Photovoltaics (POCAONTAS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,Germany,Germany,Spain,Italy,Lithuania,Portugal,United Kingdom,United Kingdom,Germany
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-11-01
End date: 2016-10-31
Duration (months): 48.0
Total project cost (EUR): 3421494.4
EU funding (EUR): 3421494.4
Participants: 10
Project status: CLOSED

Organic solar cells (OSC) feature several advantages over “classical” silicon solar cells: low cost, energy effective production, low weight and semi-transparency. This makes them apt for novel applications like, building-integrated photovoltaics (BIPV) with high market potential. However, both the efficiency and the long-term stability must be enhanced for OSCs to become profitable. POCAONTAS will develop highly efficient and stable OSCs based on tailored blends of polymers (P) with single wall carbon nanotubes (SWNT), that are ideally suited for OSCs due to their inherent stability, high carrier mobility and the tunability of optical gaps. Up to now, no breakthrough in SWNT based OSC has been achieved due to challenges with the control of SWNT-chirality, -aggregation, orbital energy mismatch and nanoscale sample morphology. Our consortium will address these issues: We will synthesize functional polymers that (i) allow for a tailored selection of SWNT chiralities, and (ii) match the SWNT energy levels to polymers for maximization of efficiency. The introduction of SWNT-P exchange protocols enables us to optimize (i) and (ii) with different polymers, avoiding compromises in performance. We will obtain optimized donor-acceptor blends, in which the SWNTs are light antenna and charge transporter. We unify leading European groups in time- (down to 10 fs) and spatially (down to 10 nm) resolved spectroscopies providing unique insights into SWNT-P interactions at the molecular level. Experts in multi-scale quantum chemical modeling will develop greater predictive power of charge transport. FLEXINK, a startup in optoelectronics materials, will provide tailored polymers. KONARKA, world leader in commercial OSCs, will build and test solar cells using our blends. Both full partners can directly exploit the project’s outcome to strengthen their market position. Three associated industrial partners provide industry internships for each ESR maximizing their career perspectives.

Keywords: g205 micro- and nanoelectronics - optoelectronics,c101 physical chemistry,p205 electronic properties of materials and transport,single wall carbon nanotubes,organic solar cells
Industrial Academic Initial Training Network towards focused treatment of age-related motor symptoms. (MOVING BEYOND)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Sweden,Germany,Netherlands,Israel,United Kingdom,Netherlands,Switzerland,Netherlands
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2017-01-31
Duration (months): 52.0
Total project cost (EUR): 2438657.11
EU funding (EUR): 2438657.11
Participants: 9
Project status: CLOSED

Gait and postural control impairments, and falls are ubiquitous among the elderly, and lead to enormous personal, occupational and health care burden. Especially patients with PD are severely affected by the progressive deterioration of these gait and postural control mechanisms. Elucidating mechanisms of age- and disease-related motor control impairments and devising focussed treatment strategies to counteract these symptoms represent major challenges for future research. Moving beyond focuses on the role of supraspinal motor control mechanisms in ageing and PD. It will span the entire spectrum from basic understanding of these mechanisms, over diagnostics to therapeutic applications of supraspinal motor control deficits. In particular, we aim to pursue the following aspects: (i) pathways of the basal ganglia, (ii) balance and postural control, (ii) sensorimotor integration aspects, (iii) fractal properties of gait, (iv) freezing of gait, and (v) central adjustment strategies. We will employ promising diagnostic strategies and tools such as (i) electroencephalography during locomotion, (ii) virtual reality, (iii) body worn movement monitors, and (iv) instrumented movement assessments. Treatment strategies in Moving beyond include (i) therapeutic cues, and (ii) modelling of an individualized training proposal. The network consists of a rare combination of experts from basic and translational research as well as from the industry. They will cover the entire range of expertise necessary and utilize cutting edge technology to educate students and fellows in the complex problem of the impact of supraspinal motor control mechanisms in ageing and PD. The comprehensive inter-sectoral and multidisciplinary training program will comprise a unique set of state of the art scienitific and soft skill training measures pursing general and individually tailored training approaches. Outreach and dissemination activites form a crucial part of Moving beyond.

Keywords: ageing,neurological disorders,parkinson,motor symptoms,diagnostics,treatment,pathways
Transforming Magnetic Resonance Spectroscopy into a Clinical Tool (TRANSACT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium,Switzerland,Czechia,United Kingdom,Germany,Netherlands,Spain,France
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-03-01
End date: 2017-02-28
Duration (months): 48.0
Total project cost (EUR): 3445287.12
EU funding (EUR): 3445287.12
Participants: 10
Project status: CLOSED

In vivo Magnetic Resonance Spectroscopy and Spectroscopic Imaging (MRS(I)) are unique, indispensable techniques for non-invasive metabolic imaging. Important areas where MRS(I) can make a difference are oncology and neurology, where metabolic changes due to, e.g., tumour formation, can be detected earlier and more sensitively than with morphological imaging modalities alone. Despite its huge proven potential, MRS(I) is not yet a routine clinical tool operated solely by clinicians. This requires reliable automation of complex procedures, strengthening standardisation and quality control. This in turn requires significant research progress and training of a new generation of scientists. Specifically, TRANSACT aims at: - Training 13 young scientists as future leaders in the field of MRS(I), capable of contributing with essential new developments such as spectral quality assurance criteria and standards, and optimal exploitation of complementarities between multi-modal magnetic resonance imaging modalities. - Pursuing research advances in theoretical and practical aspects of MRS, in particular experimental design by quantum mechanical simulation, data acquisition, data processing, data fusion and biomedical applications in oncology and neurology. - Establishing Europe as leader in the field within three sectors: academia, industry, clinic. TRANSACT links 10 academic and 4 industrial partners with complementary expertise in basic science, clinical research and information technology. Through a detailed training programme consisting of individual research projects, well-targeted secondments, scientific network-wide workshops, transferable skills courses, and individualized progress follow-up, TRANSACT will ensure a successful outcome in terms of career perspectives for the recruited researchers, continued collaboration between the partners and a more structured doctoral training in this field.

Keywords: g314 medical engineering and technology,g207 signal processing,p320 medical physics,medical magnetic resonance,medical imaging,software development,combating major diseases