Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Table-top cathodoluminescence microscope (TOPCL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands,Netherlands
Call: ERC Proof of Concept Grant (ERC-2018-PoC, 2018)
Start date: 2019-01-01
End date: 2020-12-31
Duration (months): 24.0
Total project cost (EUR): 150000.0
EU funding (EUR): 137500.0
Participants: 2
Project status: CLOSED

We propose to develop a turnkey table-top cathodoluminescence (CL) microscope demonstrator that combines electron microscopy and optical spectroscopy to make optical images with a spatial resolution as small as 20 nm. The instrument design builds on expertise on CL microscopy that I have built up during my ERC Advanced research that has led to a highly successful and highly rewarded CL research program. The new microscope design is fully user-friendly, has a footprint of only 60×60 cm, enables high sample throughput, does not need dedicated infrastructure or support, and has a projected sales price below 200 k€. This new design can serve as a unique inspection tool for nano-characterization in a broad range of technical fields, with a projected sales of 100 systems (total 20 sales price M€) per year. The new design will integrate a table-top electron microscope with a newly designed light collection and analysis system designed together with the company Delmic. The CL microscope demonstrator system will be used to perform test measurements for industrial customers in two beachhead markets to explore the market need for the new instrument and to create strong feedback of initial users on the demonstrator design. Knock-on benefits in the academic market are also expected. If successful, the project can be taken to full commercialization through the company Delmic.

Keywords: cathodoluminescence,table top electron microscopy,optical nanoscopy
Cognitive Heterogeneous Architecture for Industrial IoT (CHARIOT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Ireland,Italy,Italy,Cyprus,Greece,Belgium,Greece,France,United Kingdom
Call: R&I on IoT integration and platforms (H2020-IOT-2017, 2017)
Start date: 2018-01-01
End date: 2020-12-31
Duration (months): 36.0
Total project cost (EUR): 4928562.5
EU funding (EUR): 4928562.5
Participants: 14
Project status: CLOSED

CHARIOT will provide a design method and cognitive computing platform supporting a unified approach towards Privacy, Security and Safety (PSS) of IoT Systems including the following innovations: • A Privacy and security protection method building on state of the art Public Key Infrastructure (PKI) technologies to enable the coupling of a pre-programmed private key deployed to IoT devices with a corresponding private key on Blockchain system. • A Blockchain ledger in which categories of IoT physical, operational and functional changes are both recorded and affirmed/approved by a combination of a cognitive engine and private key hashing between the cognitive engine and IoT devices to authorise change and, likewise, invalidating any and all other changes be they malicious or otherwise. • A fog-based decentralised infrastructure for Firmware Security integrity checking that leverages a Blockchain ledger to enhance physical, operational and functional security of IoT systems, including actuation and deactivation. • An accompanying IoT Safety Supervision Engine providing a novel solution to the challenges of securing IoT data, devices and functionality in new and existing industry-specific safety critical systems. • A Cognitive System and Method with accompanying supervision, analytics and prediction models enabling high security and integrity of Industrials IoT. • New methods and tools for static code analysis of IoT devices, resulting in more efficient secure and safer IoT software development and V&V. Three Living Labs will demonstrate realistic and compelling heterogeneous solutions through industry reference implementations at representative scale, with the underlying goal of demonstrating that Secure, Privacy Mediated and Safety IoT imperatives are collectively met, in turn delivering a key stepping stone to the EU’s roadmap for the next generation IoT platforms and services.
Healthcare Performance Intelligence Professionals (HealthPros)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy,Germany,Italy,Germany,Hungary,Hungary,Netherlands,Netherlands,Denmark,United Kingdom,United Kingdom,United Kingdom,Canada,Denmark
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-01-01
End date: 2022-03-31
Duration (months): 51.0
Total project cost (EUR): 3311746.5
EU funding (EUR): 3311746.5
Participants: 19
Project status: CLOSED

Balancing between improving population health, delivering quality care for individuals, and containing costs is a timely social/economical challenge in Europe. There is great potential achieving this through healthcare (HC) system performance intelligence optimizing effective use of available HC data in countries. Effective implementation of HC performance intelligence (HPI) by skilled professionals will improve integrated service delivery; patient engagement; equality in access to HC; health outcomes; and reduce waste in HC. Translating HC data into meaningful, valid, actionable performance intelligence that is transferrable into actions to improve HC systems requires multidisciplinary skills & innovative competencies; currently not well developed in training programmes and the scientific community and missing in today’s European HC market. The ETN for HPI Professionals (HealthPros) fills this gap and directly impacts the European Research Area by training innovative “Healthcare Performance Intelligence Professionals” uniting a multidisciplinary consortium tackling private, public, academic sectors.13 ESRs will be trained in multidisciplinary innovative scientific technical and complementary skills, seconded to private / public / academic HC sectors in multiple countries and build relations with potential future employers. 5 ESRs work on PhD projects related to HC performance measurement optimizing the use of available registry and administrative data and applying statistical models to provide actionable input to HC performance management. 4 ESRs work on PhDs to translate performance intelligence into value-creating HC governance mechanisms; 4 ESRs work on PhDs aimed to impact the actual use of performance intelligence by different end-users. ESRs will have unique HC data access.

Keywords: performance intelligence pi,health data,healthcare performance measurement,governance and pi use,health outcomes,cost efficiency,quality of care,integrated care,inequality,patient engagement
Part Specific Process Optimization in SLM (PASSPORT)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: United Kingdom
Call: Part specific process optimization in SLM (H2020-CS2-CFP06-2017-01, 2017)
Start date: 2018-01-01
End date: 2019-06-30
Duration (months): 18.0
Total project cost (EUR): 599860.0
EU funding (EUR): 599860.0
Participants: 2
Project status: CLOSED

Metal Additive Manufacturing (AM) technology has developed rapidly in the last decade and has demonstrated significant potential to reduce the costs and improve the quality and efficiency of aerospace components. This can be realised through improved design freedom and light-weighting via topology optimisation, improved buy-to-fly ratios, and a reduction of tooling cost – all of which have a demonstrable impact on the carbon footprint and waste in manufacture. The “Holy Grail” of metal additive manufacturing is to manufacture reliable, high-performance metal parts with no or minimal need of post-processing. The key to unlocking this is achieving geometry-specific process parameters that enable a near-uniform thermal history and hence minimise post-processing requirements. As the European AM industry and design optimisation applications are growing, lead time and financial costs associated with optimising process parameters to ensure high-quality AlSi10Mg parts with complex geometry is a significant barrier to widespread adoption. PASSPORT seeks to remove this barrier and advance the state-of-the-art through the delivery of an ambitious experimental, analytical and software development programme. PASSPORT will: (1) Undertake a detailed characterisation of AlSi10Mg SLM parts with a unique laboratory setup (2)Employ advanced process simulations to understand and quantify the relationship between different scan strategies and part attributes. (3)Develop state-of-the-art, optimised process parameters that vary with local part topology and geometry characteristics to ensure homogeneous mechanical properties, high density and a smooth build surface. (4)Produce a bespoke, stand-alone process parameter selection software solution for AlSi10Mg SLM parts that can communicate with multiple vendors’ SLM machines. (5)Improve the time-to-market for SLM parts by removing significant cost and time-intensive burdens associated with optimising SLM builds

Keywords: additive manufacturing,process simulations,design of experiments,topology optimisation,quality assurance,selective laser melting
Asset Centric Adaptive Protection (ACAP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Ireland
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-11-01
End date: 2018-04-30
Duration (months): 18.0
Total project cost (EUR): 149977.0
EU funding (EUR): 149977.0
Participants: 1
Project status: CLOSED

The proliferation of mobile and ubiquitous computing technology is radically changing the ways in which we live our lives: from interacting with friends & family, to how we produce & consume services and engage in business. However, this pervasiveness of technologies, and their increasingly seamless integration and inter-operation, are blurring the boundaries between systems. This poses significant challenges for security engineers who aim to design systems that monitor and control the movement of digital or physical assets across those boundaries. My ERC Advanced Grant on Adaptive Security and Privacy (ASAP) is investigating ways in which security controls can change in response to changes in the context of operation of systems. However, since the monitoring of such elusive and changing boundaries is difficult, we have developed an adaptive security approach that monitors valuable assets that are managed by a system, and changes the means and extent by which those assets are protected in response to changes in assets and their values. This could radically change the way security is designed and implemented in a range of applications because it allows for a choice of appropriate protection, depending on particular requirements. In ASAP, we developed the modelling and computational capabilities of our approach, including some prototype tool fragments that demonstrate the approach in our lab. However, interest from our industrial collaborators, evidenced by direct funding of follow-on research, and the demonstration of our prototypes to senior management and potential customers, has motivated us to pursue a proof of concept (PoC) assessment of our work in a more systematic and targeted way. To this end, this ERC PoC will: 1) Develop a robust prototype demonstrator, instantiated in two application areas (access control & cloud computing); 2) Conduct a market analysis, aided by the demonstrator; 3) Subject to (2), develop a commercialisation strategy and plan

Keywords: software,requirements engineering,adaptive systems,security engineering,automated software tools
Gregory Nazianzen's methodeology of the theological arguing (Gregory)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-07-01
End date: 2017-07-29
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

The objectives of the research project are to show how a strong focus on an early Christian author’s use of classical rhetoric and philosophy (fx. Plato and Aristotle) can deepen our understanding of style and content of ancient Christian texts. This will be exemplified by detailed rhetorical and philological analyses of Gregory Naziansen’s five theological orations. Modern literary theories of reception will be employed to illuminate how Gregory used classical rhetoric and philosophy. The research project will thus revitalize traditional methods of classical philology and combine them with modern literary theories. Further I will study the composition of the cycle of the five theological orations arguing that they are written as a coherent whole. Each oration will also be studied separately clarifying which rhetorical and philosophical methods and techniques the author has used, which connections with classical pagan and early Christian (Alexandrian school) traditions they show, and which kind of theological arguing (positive and negative theology) they are characterized by. The proposed research will at the same time serve as a model for how philological and rhetorical analyses and theories of reception can be used as a tool for analyzing other ancient Christian texts. The aim of the action is further to train the researcher’s skills in using theories and methods necessary for carrying out the research project. In addition to the training in skills directly connected to the research project the researcher will also be trained in general and transferrable skills such as research administration, academic writing, writing of research applications, use of electronic resources in humanistic research, methods to disseminate research results (academic publishing, use of electronic media, teaching etc.).

Keywords: gregory nazianzen,theological orations,methodology,reception of classical traditions,negative theology
Ground Demonstration of Plant Cultivation Technologies and Operation in Space for Safe Food Production on-board ISS and Future Human Space Exploration Vehicles and Planetary Outposts (EDEN ISS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling European competitiveness, non-dependence and innovation of the European space sector
Action type: Research and Innovation actions
Countries involved: Ireland,Germany,Italy,Germany,Austria,Italy,Italy,Germany,Sweden,Netherlands,Canada
Call: Space exploration – Life support (H2020-COMPET-2014, 2014)
Start date: 2015-03-01
End date: 2019-04-30
Duration (months): 50.0
Total project cost (EUR): 4550867.5
EU funding (EUR): 4535869.0
Participants: 14
Project status: CLOSED

Humanity’s plans to further explore space require the development of bio-regenerative life support systems and in particular plant cultivation. Plants contribute to all major life support functions by producing food and oxygen, reducing carbon dioxide and recycling water and waste. Moreover, fresh crops also have a positive impact on crew psychological well-being. EDEN ISS aims to adapt, integrate and demonstrate plant cultivation technologies and operations procedures for safe food production on-board the International Space Station and for future human space exploration missions. The consortium will demonstrate operational capability of controlled environment agriculture technologies and procedures for safe food production in space. A mobile test facility will be built to provide realistic interfaces analogous to ISS. A one-year demonstration campaign at the Neumayer III Antarctic station will provide extensive testing and validation capability to increase the technology readiness level of key subsystems to 6. Further developing these technologies and operations procedures, including food quality and safety measurements, will also contribute to Europe’s interest in resource efficient crop cultivation, saving energy, countering the climate change and securing the supply of healthy and safe food. The interdisciplinary nature of EDEN ISS combines research in space engineering, horticulture, food science and microbiology. Leading space industries (Thales Alenia Space Italia, Airbus Defense and Space, Telespazio), research organizations (DLR, CNR, AWI), SMEs (Liquifer, Heliospectra, EnginSoft, Aero Sekur) and academia (Wageningen UR, University of Guelph, Limerick Institute of Technology) from six European countries (Germany, Ireland, Italy, Sweden, Austria, the Netherlands) and Canada join forces in a unique consortium to prepare the ground for further innovative research and development in human spaceflight and terrestrial applications.

Keywords: space plant growth chamber,controlled environment agriculture,food supply for antarctic stations,vertical farming,molecular farming
TGF-beta mediated crosstalk between cancer (stem) cells and tumor microenvironment in pancreatic cancer metastasis (PDA_TGFb)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-02-12
End date: 2019-07-13
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

More than 50% of all pancreatic cancer patients suffer of metastasis either at the time of diagnosis or as recurrent disease after therapy. During metastatic dissemination, cancer (stem) cells shed into the blood stream and seed the liver as isolated entities. Genetic alterations underlying these processes have not been identified thus far. Therefore, it is currently not possible to discriminate which patients are at higher risk of developing metastasis or to design targeted therapies to prevent this process. Interestingly, a broad subset of pancreatic cancers (PDAs) are characterized by high TGF-beta superfamily ligands (TGFB_SLs) levels (TGFβ1, Nodal and Activin) and by prominent TGF-beta signaling in tumor stromal cells. The main goal of this project is to unravel how the microenvironment of the primary tumor helps tumor cells to colonize a distant organ. Specifically, PDA_TGFB aims to: 1) Identify and characterize the cancer (stem) cells and stromal cells involved in the crosstalk responsible of the tumor progression; 2) Define the role of TGFB_SLs during the tumor-stroma crosstalk and Identify the signaling pathways involved in the crosstalk; 3) Determine whether the metastatic cells activate the TGFB_SLs-driven stromal response at the metastatic site. By using a multidisciplinary approach that includes the use of cell culture models and animal models, in which TGF-beta signaling (and/or target genes) is selectively induced or abolished, we expect to identify additional factors involved in the metastatic process as well as to identify ways to interfere with the metastatic niche within the liver. Overall, this study will clarify the role of TGF-beta signaling in the metastatic process, thus opening novel avenues for the development of diagnostic and therapeutic strategies for PDA.

Keywords: tgf beta,cscs,microenvironment
Linking Climate and Development Policies - Leveraging International Networks and Knowledge Sharing (CD-LINKS)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Fighting and adapting to climate change
Action type: Research and Innovation actions
Countries involved: India,Germany,Italy,Austria,China,Russian Federation,Greece,France,Netherlands,Netherlands,United Kingdom,Brazil,Japan
Call: Linkages between climate change actions and sustainable development (H2020-SC5-2014-two-stage, 2014)
Start date: 2015-09-01
End date: 2019-09-30
Duration (months): 49.0
Total project cost (EUR): 5212962.5
EU funding (EUR): 5037962.5
Participants: 17
Project status: CLOSED

An important question for policy makers, in the G20 and beyond, is how to bring climate action into the broader sustainable development agenda. Objectives like energy poverty eradication, increased well-being and welfare, air quality improvement, energy security enhancement, and food and water availability will continue to remain important over the next several decades. There have been relatively few scientific analyses, however, that have explored the complex interplay between climate action and development while simultaneously taking both global and national perspectives. The CD-LINKS project will change this, filling this critical knowledge gap and providing much-needed information for designing complementary climate-development policies. CD-LINKS has four overarching goals: (i) to gain an improved understanding of the linkages between climate change policies (mitigation/adaptation) and multiple sustainable development objectives, (ii) to broaden the evidence base in the area of policy effectiveness by exploring past and current policy experiences, (iii) to develop the next generation of globally consistent, national low-carbon development pathways, and (iv) to establish a research network and capacity building platform in order to leverage knowledge-exchange among institutions from Europe and other key players within the G20. Through six highly integrated work packages – from empirical research to model and scenario development – CD-LINKS will advance the state-of-the-art of climate-development policy analysis and modelling in a number of areas. The project aims to have a pronounced impact on the policy dialogue, both nationally and internationally: an important outcome of the project will be a list of country-specific policy recommendations for effectively managing the long-term transformation process. These recommendations will point out opportunities for policy synergies and at the same time respect political and institutional barriers to implementation.

Keywords: low carbon development pathways,linkages between sustainable development and climate change,integrated assessment