Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Interactive Research in Music as Sound:Transforming Digital Musicology (IRiMaS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Ireland,France,United Kingdom,United Kingdom
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-10-01
End date: 2023-03-31
Duration (months): 66.0
Total project cost (EUR): 2471416.0
EU funding (EUR): 2215331.0
Participants: 4
Project status: SIGNED

In an age when technology is revolutionizing the ways in which music is made and distributed, this project proposes correspondingly to transform approaches to musicology, moving from a primarily fixed, text-based approach to one that incorporates as an integral feature the interactive and aural. It brings skills and expertise from music technology to assist in the development of research strategies and software to enable musicological research to engage more directly with sound. It will pioneer a ground-breaking approach to music research in which dynamic interaction with sound is fundamental and music’s temporal and transient nature are central to research investigations and their dissemination, presenting a significant conceptual challenge to the traditional textual bias of much musical research and leading to new enhanced modes of musicological knowledge. Unlike current Digital Musicology, rather than using software primarily to extract quantized data, IRiMaS facilitates research through dynamic interactive engagement with sound. The interactive approach will be developed in the context of three Case Studies in specific areas where prioritizing the aural is of particular significance. The Case Studies will focus on Spectralism in the field of Contemporary ‘Art’ Music; Tracking the Creative Process in Free Improvisation; and Folk Songs in Performance in the field of Ethnomusicology. Each study will produce substantial ground-breaking musicological outcomes in the form of software packages (as is appropriate to the nature of the project) and associated articles discussing the approach taken. They will also assist in working towards the development of models and generic tools to help establish the wider adoption of this interactive approach. Building on the PI's previous experience in related areas, researchers from musicological and technical backgrounds will come together to help realize these ambitious aims.

Keywords: musicology,music technology,music analysis,contemporary music,ethnomusicology
Dynamics of Attentional Networks in the Human Brain in Health and Disease: Evidence from Intracerebral and MEG Recordings (DynamAtt)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 185076.0
EU funding (EUR): 185076.0
Participants: 1
Project status: CLOSED

Our ability to explore the environment and to rapidly respond to external events depends on attentional processes, which set priorities based on our goals and on the salience of external stimuli. Distinct dorsal and ventral fronto-parietal networks process human visual attention, but little is known about their dynamics, because hitherto our knowledge mostly depended on fMRI, which has limited resolution. This proposal will utilize intracerebral recordings in human participants, a method with unrivalled spatial and temporal resolution, during the performance of attention tasks. Patients with drug-refractory epilepsy, exhibiting normal attention, who are implanted with depth electrodes in preparation for surgical treatment, will be recruited. The data collected will enable the Fellow to pinpoint the neural populations supporting different aspects of attention within each network, discern their temporal behavior and analyze the dynamics of the interaction between the two networks. The acquired results on the normal function of attention networks will guide the study of patients suffering from hemispatial neglect, a common disabling condition affecting attention functions, using non-invasive MEG recordings. The results will reveal the pathological alterations in attention networks' dynamics, resulting from right hemisphere lesions. Hence, the insights gained through these innovative investigations will extend our knowledge on attention processes in health and disease, and promote the development of better rehabilitation methods.

Keywords: attention,intracerebral recordings,frontal cortex,parietal cortex,temporal cortex,occipital,cortex,human brain
Philosophy and Genre: Creating a Textual Basis for African Philosophy (PhiGe)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Germany,United Kingdom,United Kingdom
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2020-04-01
End date: 2025-03-31
Duration (months): 60.0
Total project cost (EUR): 1997762.0
EU funding (EUR): 1715318.25
Participants: 3
Project status: SIGNED

The project pioneers a multilingual approach to African philosophy, based on an understanding of philosophy as expressed through texts. In contrast to definitions of philosophical texts as non-fictional, written sources (Hountondji), we insist on a much more inclusive definition of “text”: both oral and written texts, fictional and non-fictional ones, public and private ones are considered in this project. A rigorous study of texts, working across multiple genres and several languages, is the first step in the development of an African philosophy derived from local African cultures, rather than from global, colonial or neo-colonial concerns, as is to date the case in the “mainstream” discipline of “African Philosophy”. This project establishes such a textual basis for African philosophy. This bottom-up approach necessitates a reconsideration of the nature, methods, and themes of philosophy, but also of its textual strategies, its use of language, of the nature of representation, and of the relationship between imaginative literature and theoretical thought. The key premise of our project is that to understand the philosophical meaning of texts, it is necessary to start with an analysis of textual genres. Genres anchor texts in context, in culture and language. How exactly does genre impact meaning? To answer this central question of our research, we work comparatively on several genres of literature in eight African and European languages. The case studies include the essay in Ciluba and French, the novel in Swahili, Shona, Ciluba, Lingala, French, and English, digital texts such as blogs and social media, scenario planning narratives, Sufi poetry in Swahili and Wolof, and Alexis Kagame’s poetic work in Kinyarwanda and French, travestying the traditional genres of dynastic, heroic and pastoral poetry. Challenging the conventional limits of both philosophy and literature, our approach allows new, topical philosophical concerns to emerge from this textual basis.

Keywords: african philosophy,textual study of philosophy,literary genre
NeuralShape: the first deep-learning based software to improve the engineer ‘work. (NeuralShape)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-03-01
End date: 2019-06-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

With the new technologies’ development and the large-scale adoption of autonomous and electric cars, drones, as well as humanity´s quest for green energy, new designs become much more sophisticated, with complex simulations, producing vast amounts of data. This, as a results force tools like CAD and CFD to be rethought. Companies need new tools to improve existing designs without engineers having to spend more time to make a good and accurate design. At Neural Concept (a Swiss company founded in 2017) we have develop a solution to overcome these needs: NeuralShape, the first deep learning system to improve the engineers´work. With NeuralShape Engineers will save time, energy and economical cost, while providing optimal design choices with very precise results. Based on the good performance of our prototypes being currently tested for different business cases (UAV, hydrofoil and speed bicycle), we aim to optimize the software and scale-up technology to fulfil the technical needs of different European markets. This CAD and CFD market is expected to be €6.5B by 2021 (CAGR 7%). Our customers will be engineering companies as well as Engine Automotive, Aeroespace and Green energy manufacturers. €6M sales projection has been estimated for the third year of commercialization.

Keywords: deep learning,artificial inteligence,computational fluid dynamic cfd and computer aided design cad systems,neural network
Literary and Visual Cultures in the shaping of female monastic life (Iberian Peninsula, c. 1350-1550) (LITVIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-07-01
End date: 2023-06-30
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: SIGNED

This project aims to assess the existence of interrelations between the nuns’ literary and visual cultures in the shaping of female monastic life in the Iberian nunneries (c. 1350-1550), since the rising suggestions on the mutual influences between the use and development of texts and artworks in conventual context demand that these phenomena be analysed as part of the same equation in order to be fully understood. By addressing these communities' visual and literary cultures and their religious praxis from a joined perspective, LITVIS will contribute for the further comprehension of artworks, texts and rituals that shaped monastic life, unveiling information about their development, functionality and reception that could not be obtain when inquiring those phenomena individually as has been happening until now, not only in Iberia, but also at an European level. The surviving of important elements of material culture in the Iberian Peninsula - such as conventual inventories, books and artworks -, can enable a study that will further analyse what informed the nuns’ choice and use of artworks and texts and if and how both media were interconnected in monastic life. This entails a change of focus from the isolated object (an artwork or text) and its formal characteristics, to its functionality and reception, acknowledging it as part of the religious praxis to which it bears witness. Such a task demands an interdisciplinary study that brings together the fields of Art History, Literature, and Religious History, borrowing notions born within the Cultural Studies, such as Visual Culture and Literary Culture.

Keywords: female monasticism,medieval conventual art,nuns literacy,conventual literary culture,nuns agency
Muscle Stress Relief: An integrated research program linking together basic research on secondary myopathies in stress states to innovative translation in applied myology. (Muscle stress relief)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Germany,Germany,South Africa,Italy,Germany,Germany,Germany,Greece,Greece,Greece,France,Netherlands,United States,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2016-03-01
End date: 2020-02-29
Duration (months): 48.0
Total project cost (EUR): 1606500.0
EU funding (EUR): 1458000.0
Participants: 21
Project status: CLOSED

A diverse variety of medical or lifestyle conditions lead to a progressive loss of muscle force by functionally impairing myofibril contractility and causing ultimately myofibril loss. Major underlying risk factors of chronic muscle force loss are ageing, inactive lifestyles, and unbalanced nutrition. Together, these factors are predicted to lead to an endemic incidence of muscle weakness both in the developed countries. Clinical research on the mechanisms involved requires a multidisciplinary approach covering aspects of ageing, metabolism, and on the humoral cross-talk of muscle with other key organs including heart, liver, kidney, and lung. To achieve this, six European groups with complementary expertise in inter-organ-cross-talk during stress-induced secondary myopathies will team-up with three leading teams in the U.S. with expertise in myopathy animal models, myofilament proteins and translation of muscle research into therapeutic interventions, and with one team from South Africa with cutting-edge expertise in the regulation of regenerative capacities in muscle. Importantly, five SMEs will participate in this RISE network that provide expertise in early muscle disease detection, monitoring, and the developing preventive strategies: Their knowledge on muscle disease detection at early stages and their monitoring during interventions will promote translational innovation. To implement innovation and our joint research program, both early stage and advanced researchers will be seconded from the academic nine teams to these five SMEs and vice versa. Thereby, this RISE scheme will establish a long-term collaborative University-SME driven translational innovative research program innovation in our interdisciplinary field of growing socioeconomic medical importance.

Keywords: muscle weakness,sarcopenia and atrophy,critical illness myopathy,myasthenia gravis,diaphragm failure,myofiber force,transgenic mouse models,myology,gene therapy
PYHIN-Regulated Memory T cell protection for Infectious Diseases (PYRAMID)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 184590.72
EU funding (EUR): 184590.72
Participants: 1
Project status: SIGNED

Pyrin and HIN domain (PYHIN) proteins play an integral role in the innate immune response to DNA and RNA viruses via direct detection of viral DNA and transcriptional regulation of pro-inflammatory and anti-viral cytokines respectively. Although expressed by various cells of the myeloid lineage, including some classical antigen presenting cells, the role of PYHINs in the context of T cell-mediated adaptive immunity has yet to be investigated. This project aims to elucidate how PYHIN proteins modulate acute and long-term CD8+ memory T cell responses to influenza A virus (IAV), a respiratory RNA virus which causes significant morbidity and mortality annually. Current seasonal IAV vaccines, exhibit variable efficacy and the neutralising antibodies they induce cannot protect against alternative IAV strains, particularly those with pandemic potential. In contrast, IAV-specific CD8+ memory T cells can elicit such cross-protective immunity by targeting conserved viral proteins, thus making the identification of mechanisms which give rise to these cells high priority in the search for a universal IAV vaccine. Herein, we will perform in-depth characterisation of PYHIN expression in human and murine dendritic cells. We will also perform genetic manipulation of PYHIN expression in primary immune cells to interrogate functionality and undertake infection studies in transgenic mice lacking certain PYHIN family members to determine their role in the formation of IAV-specific T cell memory in vivo. Overall, this project is extremely timely, providing crucial mechanistic insight which can inform rational vaccine design aimed at eliciting cross-protective T cell responses to respiratory RNA viruses.

Keywords: viral sensing,pyhin,anti viral,innate,adaptive,t cell memory,influenza,dendritic,cd8 t cell
Playing Quantum (QPlay)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Coordination and support actions
Countries involved: Finland
Call: FET Innovation Launchpad (H2020-FETOPEN-4-2016-2017, 2017)
Start date: 2018-09-01
End date: 2020-02-29
Duration (months): 18.0
Total project cost (EUR): 99405.0
EU funding (EUR): 99405.0
Participants: 1
Project status: CLOSED

Hundreds of millions of people worldwide are opting out of reality for larger and larger chunks of time to play video games. This “mass esodus” to game spaces is creating a massive virtual silo of cognitive effort and collective attention lavished on game world instead of real world. Game industry is more and more interested in channeling this enormous amount of human brainpower by designing games with a purpose. Several successful examples show that it is indeed possible to develop video games in which people solve computationally intractable research problems as a side effect of playing. Humans are better than computers at performing certain tasks because of their intuition and superior visual processing. Human intuition has been proven useful, for example, in exploring the complex configuration landscape typical of quantum optimal control theory. The identification of optimally controlled quantum probes is an ideal candidate for gamification. QPlay’s vision is the production and launch of massively-collaborative online video games solving research tasks in quantum technologies by means of hybrid human-computer interaction, complemented with machine learning algorithms. To achieve this vision, we need to build hybrid industries and unconventional partnerships, involving academia, so that game researchers, designers and developers can work with quantum physicists, machine learning experts, and educators to harness the power of games for research. QPlay aims at i) exploring the feasibility of an exploitation path by coordinating and supporting the assembling of the right knowledge, skills and resources, ii) the identification of strategic partners, iii) the exploration of the market, and iv) the development of a business plan. In this way it serves as a launch pad to a novel commercial product with the potential to revolutionise quantum research, accelerate the creation of quantum technologies industries while actively engaging, informing and educating society.

Keywords: citizen science,quantum technologies,quantum optimal control,game development,machine learning
Rule-algebraic Simple Rewriting (RaSiR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 2
Project status: CLOSED

The basis for this project consists in a mathematical framework previously developed by the applicant that allows to describe graph rewriting systems algebraically, the so-called rule algebraic framework. In order to advance and valorise the concept, this project proposes to develop a general concept for rule-algebraic simple rewriting (RaSiR), both for conventional graph rewriting and for a novel form of simplicial rewriting. Secondly, RaSiR will serve as the basis for developing rule-algebraic variants of trace compression and observable-update algorithms for the rewriting system Kappa. The final aim of the project consists in developing and implementing the so-called observable-centric bootstrapping algorithm (OCBA) as a module for the simulation suite KaSim for the Kappa language. Kappa is predominantly used for simulating biochemical reaction systems, which typically display an extremely high combinatorial complexity. The algorithms and software modules developed in this project will provide in particular an alternative to pure stochastic simulation via the SSA algorithm as currently implemented in KaSim, in the form of the OCBA module. This module will admit the generation of approximate observable distributions from individual pure states of the system by calculating algebraically truncations of the formal solution of the chemical master equation as well as the induced observable update functions. The project shall be hosted by Dr. Jean Krivine of the PPS team at IRIF at the University Paris-Diderot in France. Dr. Krivine is one of the two main developers of the KaSim simulation suite, and moreover one of the world experts in the theoretical and practical development of the programming language Kappa. IRIF will provide an ideal environment for the applicant to develop new skills, to be part the very interdisciplinary research team PPS, and to communicate and valorise the project results to the greater biochemical and systems biological simulation community.

Keywords: rule based modelling,kappa language,algebra based algorithms