Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Potato crop effective management strategies to tackle future pest threats (PATAFEST)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Spain,Ecuador,United Kingdom,Belgium,Italy,Germany,France,Czechia,Israel
Call: Emerging and future risks to plant health (HORIZON-CL6-2022-FARM2FORK-02-two-stage, 2022)
Start date: 2023-06-01
End date: 2027-05-31
Duration (months): 48.0
Total project cost (EUR): 6097603.75
EU funding (EUR): 6097603.75
Participants: 18
Project status: SIGNED

Potato is a key crop in Europe (€12.4 billion, 2020). However, it is considered vulnerable to a variety of pests and soil-borne pathogen diseases. One of the most important pests is caused by bacteria Candidatus Liberibacter solanacearum (CLso), causing a disease known as zebra chip (ZC). The introduction of CLso bacterium on potato is mainly linked to the presence of the vector psyllid Bactericera cockerelli (BC) causing severe damage, both in terms of yield losses and quality. Main potato postharvest diseases as dry rot, black dot and silver scurf, are caused by soil-borne pathogens that have incidence in both field and storage. All these potential threats may result. in significant economic losses in the potato industry and food losses. The European regulatory framework for potato’s imports and production is very strict. However, globalisation, climate change, economical drivers, as well as the political context (EU Green Deal target of 50% pesticides reduction) are threatening the entrance of emerging potato pests and the incidence of soil-borne pathogen disease in postharvest storage. PataFEST and its 18 complementary partners, including the international cooperation with Ecuador, aims: 1) to characterise at molecular level the ecological pest spread pathway and identify potato disease resistance varieties against CLso and postharvest pathogens, 2) provide effective preharvest plant and soil treatments against CLso vector and soil-borne pathogens combined with other cutting-edge digital technologies such as image analysis tools (mobile app) and artificial intelligence predictive models; 3) develop postharvest technologies (biocontrol coating solution, controlled atmosphere storage and volatile organic compounds (VOCs) sensors) to control the incidence of soil pathogens and maintain the quality of potato tubers stored. These strategies and technologies will be incorporated into an Integrated Pest Management approach to evaluate their performance at final TRL5.

Keywords: solanum tuberosum plant and soil health sustainable fungicides postharvest pathogen diseases zebra chip candidatus liberibacter solanacearum resistant genes emerging pests crop improvement
Resolving temporal immune responses of Arabidopsis roots to infection by Fusarium oxysporum at the single-cell level (SC-Foxy)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-03-10
End date: 2025-03-09
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: CLOSED

Pathogen-caused diseases represent one of the biggest problems in agriculture. A detailed mechanistic understanding of plant defenses against pathogenic invasion and disease progression is therefore a vital research topic, forming the foundation for the creation of more resistant crop varieties. However, at present, most studies aimed at this utilize ‘omics’ approaches or mutant analyses, which lack resolution and only allow limited understanding of plant-pathogen interactions at the single-cell level. Thus, our current models of plant-pathogen interaction do not include strictly local or temporal responses. The aim of this proposal is to address this with a pathosystem consisting of the model plant Arabidopsis thaliana and strains of Fusarium oxysporum, a destructive fungal pathogen of several food crops. A unique near-native imaging setup, enabling the simultaneous study of growth and infection of plant and fungus with single-cell resolution, will be used. The work in this proposal will probe the responses of individual plant cells to both pathogenic and beneficial F. oxysporum strains, in a native tissue context from the onset of invasion to full disease development. This will generate novel insights into cellular mechanisms employed by plants to fight off pathogenic invaders, while accommodating beneficial endophytes. By using a novel in vivo cell-labeling technique, exploiting the fungal avirulence effector secretion system, a single-cell transcriptome atlas exclusively of cells undergoing acute colonization will be generated. Moreover, as root barriers represent a physical hindrance for pathogen invasion, mutants affected in physical defenses will be tested. Combined, this proposal will expand our current models of immune responses to include specific cells, regions or tissues, and temporal aspects with high resolution. Such knowledge is important to develop next-generation agricultural tools and will be applicable to combat current and arising diseases.

Keywords: plant microbe interactions plant immunity
AgroBiogel International Scale-up (Agrobiogel)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Austria
Call: Green Deal innovations for the Economic Recovery (HORIZON-EIC-2021-ACCELERATORCHALLENGES-01, 2021)
Start date: 2022-07-01
End date: 2025-05-31
Duration (months): 35.0
Total project cost (EUR): 3407000.0
EU funding (EUR): 2384900.0
Participants: 1
Project status: SIGNED

Agrobiogel is a novel soil improver that stores and slowly releases water and fertilizer. It addresses many of the pain points and challenges of modern farming, forestry, plant nurseries and green houses all over the world: (1) save up to 40 % irrigation water (2) protect plants/crops from increasing droughts and erratic rainfall patterns (3) reduce agricultural input costs (4) convert agricultural non productive soils, including 100 % sand soil, into agriculture productive soils (5) Matching the urgent desire to replace expensive non biodegradable fossil based hydrogels with much cheaper organic hydrogels (6) Agrobiogel as a product of widely under-utilised lignin produced by the Pulp and Paper industry as well as the emerging biorefinery helps create value for this raw material thereby helping them not only expand their product portfolio but also reduce their carbon footprint and greenhouse gas emissions.

Keywords: climate resilience,carbon sink,water footprint,crop drought protection,environmental and green technologies
Framework for defining climate mitigation pathways based on understanding and integrated assessment of climate impacts, adaptation strategies and societal transformation (KNOWING)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Climate
Destination: Climate sciences and responses for the transformation towards climate neutrality
Action type: Research and Innovation actions
Countries involved: Austria,Italy,Spain,Netherlands,Germany,Estonia,Croatia,United Kingdom
Call: Better understanding of the interactions between climate change impacts and risks, mitigation and adaptation options (HORIZON-CL5-2021-D1-01, 2021)
Start date: 2022-06-01
End date: 2026-05-31
Duration (months): 48.0
Total project cost (EUR): 6204910.0
EU funding (EUR): 6204906.5
Participants: 21
Project status: SIGNED

According to the EU’s Climate Adaptation Strategy (COM(2021) 82), “improving knowledge and managing uncertainty” is key for realising the vision of a climate neutral and climate-resilient Union, as “Climate change is having such a pervasive impact that our response to it must be systemic”. Thus, there is an urgent need for an integrated approach for an enhanced understanding of the interaction, complementarity and trade-offs between adaptation and mitigation measures, especially regarding the expected increase in region-al mean temperature, precipitation and changing soil moisture (IPCC AR6 WG I). Furthermore, this under-standing and knowledge needs to be provided to a broad audience to support local authorities in EU partner countries in developing regional programmes. KNOWING aims to develop a modelling framework to help understand and quantify the interactions between impacts and risks of climate change, mitigation pathways and adaptation strategies. The framework will be used to assess thAdvancing climate science and further broadening and deepening the knowledge base is essential to inform the societal transition towards a climate neutral and climate resilient society by 2050, as well as towards a more ambitious greenhouse gas reduction target by 2030. There is a need for research that furthers our understanding of past, present and expected future changes in climate and its implications on ecosystems and society, closing knowledge gaps, and develops the tools that support policy coherence and the implementation of effective mitigation and adaptation solutions. Currently, there is a lack of knowledge of the Earth system and the ability to predict and project its changes under different natural and socio-economic drivers, especially regarding complex interrelations, rebound effects and behavioural aspects. Therefore, a holistic, system-aware and behaviour centred approach is needed to identify and implement realistic and effective climate mitigation pathways.

Keywords: model framework societal transformation mitigation pathways,adaptation mitigation trade offs
Single pilOt Line Operations (SOLO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (JU-JTI)
Countries involved: France,Belgium,Spain,Germany,United Kingdom
Call: Industrial Research & Validation for Air-Ground Integration and Autonomy (HORIZON-SESAR-2022-DES-IR-01, 2022)
Start date: 2023-07-01
End date: 2026-06-30
Duration (months): 36.0
Total project cost (EUR): 8368981.5
EU funding (EUR): 4861172.93
Participants: 10
Project status: SIGNED

SOLO intends to pave the way for the commercial operations of next generation airliners proposing Single Pilot Operations, which are anticipated within the next decade. To this aim, SOLO encompasses one single Operational solution that will produce a TRL 4 ATM Concept of Single Pilot Operations. This will initiated based on previous works initiated by Airbus and ATR with the support of French partners (DSNA, EUROCONTROL, ENAC) and, as well, be based on the technological bricks developed during those previous R&T activities. In support to Airbus and ATR, the maturation and validation of this concept will be done with the formal cooperation of DFS, ENAIRE/CRIDA, EUROCONTROL, DSNA, NATS and INDRA. Indeed, one major constraint for the TRL 4 concept will be to reduce to the minimum necessary the impacts on ATC tools and procedures. Airline functions and tools will need to be enhanced to prepare and execute Single Pilot Operations, in addition to the major evolutions needed at the cockpit side (not the purpose of SOLO). Several airlines had -on an anonymous way- supported Airbus and ATR for several years. It is planned that a similar way of working will be done during the execution of the project. In the end, the TRL 4 Concept of Operations (instantiated by a comprehensive SPR/INTEROP/OSED) will feed further, more specific R&T activities and as well provide solid basis to various standardization and regulatory bodies such as ICAO, EASA, FAA, CAAC.

Keywords: single pilot atc atm
Delivery of liquid Hydrogen for Various Environment at High Rate (DelHyVEHR)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Innovation actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: France,United Kingdom,Switzerland,Romania,Belgium,Spain
Call: Demonstration of LH2 HRS for Heavy Duty applications (HORIZON-JTI-CLEANH2-2023-1, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 5064971.25
EU funding (EUR): 3711901.13
Participants: 13
Project status: SIGNED

Liquid hydrogen is a key solution to enable strong carbon reduction for energy, chemical and mobility industries. If technologies are mature for light vehicles fast refuelling, it is still a challenge for heavy duty applications, hampering massive environmental gains for aviation, maritime, railroad. DelHyVEHR offers to fill the gap of liquid hydrogen distribution technologies by driving the maturation to the demonstration at TRL 6 of the large-scale refuelling station and each main systems with a specific focus on pumping, metering, loading and boil-off gas management systems. DelHyVEHR main objectives are to: • Develop a high flowrate (>5 t/h and up to 6 t/h) transfer cryogenic pump for LH2 refuelling stations with high efficiency (>60%) and high reliability (Mean Time Between Maintenance > 3000h) • Develop and adapt loading and dispensing systems for the high-flowrate refuelling station • Develop and optimize a boil-off gas management system enable to recover >80% of the hydrogen • Design, build and operate the LH2 refuelling station to refill a cryogenic storage of 4-6 m3 and with integrated technologies demonstrated over long-time operation (>10 h) • Assess economic, environmental impacts and policy suitability of the technologies and demonstrator with expected cost reduction of investments and operation of LH2 bunkering stations at 1.5 €/kg and deliver H2 carbon footprint aligned with RED II legislation below 3.38 kgCO2/kgH2 • Ensure safety of the LH2 bunkering station and its operation DelHyVEHR demonstration before 2027 will enable commercialisation before 2029 to target 15 refuelling stations in 2030 and up to 81 stationsin 2040 for shipping, aviation and railroad markets. To succeed, DelHyVEHR gathers 13 EU leading partners covering the whole value chain from component development to system demonstration and assessment, along with an advisory board of worldwide leading H2 end-users.

Keywords: liquid hydrogen,refuelling station,high flow rate,maritime,aviation,railroad
The Genetic basis of host resistance and pathogen virulence in the Septoria-Wheat pathosystem (SEPTOWHEAT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy,France,United Kingdom
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-07-01
End date: 2025-06-30
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 3
Project status: CLOSED

Increasing agricultural sustainability has become more than ever a priority. In this sense, wheat plays a central role in EU agriculture as a major crop, and controlling yield losses due to diseases can be a serious bottleneck for agricultural sustainability. Septoria tritici blotch (STB) caused by Zymoseptoria tritici, is a globally occurring fungal disease that causes severe yield losses on wheat and is the source of a massive fungicide applications in the EU. Furthermore, Z. tritici populations evolve rapidly and their adaptation to the proposed control measures (monogenic resistance, fungicides) is a well-known phenomenon. Thus, breeding polygenic STB-resistant varieties is timely and represent the most durable and economic way to limit disease epidemics and reduce fungicide dependecy. However, this cannot be achieved without a thorough understanding of host-pathogen interactions and an extensive knowledge of (1) host resistances and their effectiveness in pathogen populations (2) pathogen virulence factors and mechanisms of overcoming host resistance. The research proposed here, “The Genetic basis of host resistance and pathogen virulence in the Septoria-Wheat pathosystem (SEPTOWHEAT)”, aims to address these gaps by using state-of-the-art genomics and genetic resources, to meet the challenges of STB resistance breeding and pathogen’s rapid adaptation. The project will be articulated in three integrated objectives: (1) genetic mapping of novel resistance loci/genes from diverse tetraploid wheats (2) identification of the corresponding pathogen (a)virulence genes and (3) development of diagnostic molecular assays to accelerate resistance introgression into elite pre-breeding material. SEPTOWHEAT will have numerous outcomes on durable STB resistance, reducing fungicide use within the EU, and will significantly contribute to our understanding of host-pathogen genetic in an important agricultural system.

Keywords: plant genetics,genomics,plant breeding,fungal pathogens,disease resistance,virulence genes,gwas,marker assisted selection
Re-Defining early Parkinson’s disease (Re-Start PD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-08-01
End date: 2030-07-31
Duration (months): 60.0
Total project cost (EUR): 2463687.5
EU funding (EUR): 2463687.5
Participants: 2
Project status: SIGNED

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, but current diagnostic criteria identify individuals late, impeding the development of neuroprotective therapies: There is the critical yet unmet need to identify the disease onset timely and to define the inception of pathology. Advancing recognition of early motor deterioration and coupling it with biological evidence of pathological α-synuclein will overcome present barriers and tackle the questions when and where PD starts. Isolated REM sleep behavior disorder, confidently detectable by polysomnography, signals an early α-synucleinopathy. Overseeing a large cohort, I will integrate multimodal motor data on speech, facial expression, hand movements, gait, and long-term actigraphy within a machine learning framework, permitting a tablet-based application for highly mobile uses. This earliest PD motor-fingerprint, common to PD in general, will enable prospective large-scale screening from an unselected population. Motor phenotype detection will be paired with biological confirmation of pathological α-synuclein species in the cerebrospinal fluid using precise seed aggregation assays (SAA), capturing imminent PD earlier than ever before. This universal identification of the earliest phase of PD will allow to explore the initial spread of α-synuclein pathology, elucidating variations of pathology initiation: I will employ α-synuclein SAA on biosamples from the olfactory epithelium (brain-first) and the peripheral autonomic nervous system (body-first) to decode fundamental subtypes. Re-Start PD pairs general PD characteristics - its primal motor phenotype and its biological α-synuclein signatures - outlining the earliest phase of PD prospectively and being readily transferable for broad application to kickstart timely therapeutic innovations. Complementary biobanking, brain-imaging, and follow-up of this unique cohort will foster further biomarker development and subtype determination.

Keywords: parkinson s disease,rem sleep behaviour disorder,machine learning,early diagnosis,motor behavior,alpha synuclein,seed amplification assay
Digital Twin-sustained 4D ecological monitoring of restoration in fishery depleted areas (DIGI4ECO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Ocean, seas and waters
Destination: Ocean, seas and waters
Action type: Innovation actions
Countries involved: Spain,Italy,Ireland,Denmark,Cyprus,Germany,Sweden,France,Belgium,Greece
Call: Integration of biodiversity monitoring data into the Digital Twin Ocean (HORIZON-MISS-2022-OCEAN-01, 2022)
Start date: 2024-03-01
End date: 2028-02-29
Duration (months): 48.0
Total project cost (EUR): 11251898.75
EU funding (EUR): 9489597.5
Participants: 18
Project status: SIGNED

To unlock and boost new discoveries that will be crucial to face climate change, and regulate human actives, which will be key for both environmental conservation and socio-economical activities. We aim to make all the past, current, and future biological and oceanographic data available to everybody. Therefore, we will use relevant sleeping data, by designing new tools and methodologies to use and process relevant data already collected for different institutions, which may come from physical and chemical sensors, or video cameras. We will also harmonize the data, promoting tools to make them the standard among researchers and data-generator actors, developing protocols and best practices, like standardization tools as PUCK among marine sensors and monitoring platforms, and unifying libraries and resources (e.g., FanthomNet or Emodnet). At the same time, we will ensure a secured, sustained and reliable data flows by developing auto correction/validation methodologies and by publishing a set of tools and pipelines to ensure the trustfulness of data. Moreover, we will be using economies of scale and enhanced standardization to conduct several pilot sea-basin scale monitoring tests using two strategies: (1) using existing relevant sleeping data form online and partner repositories, and (2) using new data collected during field test demonstrations. Here, we will develop tools to better support assessment: studying and identifying key indicators and mechanisms to extract them from the data will generate the appropriate guidelines for policymaker, researchers, and socioeconomic sectors. Making those tools, methodologies, and implementations open source for the researchers and public in general will boost their utilization and improvement, even after the conclusion of the present project. With these demonstration examples, the international collaboration, and open source resources, we aim to make our proposal by fact the standard gold to follow in the following years

Keywords: digital twin of the oceans,real time monitoring,historical data,data modelling,oceanographic modelling