Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
TALOS-Artificial Intelligence for Humanities and Social Sciences (TALOS-AI4SSH)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Coordination and support actions
Countries involved: Greece
Call: ERA Chairs (HORIZON-WIDERA-2022-TALENTS-01, 2022)
Start date: 2023-03-01
End date: 2028-02-29
Duration (months): 60.0
Total project cost (EUR): 2493395.0
EU funding (EUR): 2493395.0
Participants: 1
Project status: SIGNED

The proposed project aims to establish a Centre on Artificial Intelligence for Humanities and Social Sciences, under the leadership of outstanding academic Christophe Roche, at the University of Crete, in Widening country, Greece. Christophe Roche, currently a Professor of Artificial Intelligence in France, has proven research and innovation excellence, keen management skills, and extensive academic, standards and industry connections; most importantly, he has already established collaborations with the University of Crete and has committed to work with its staff to help build a leading-edge Centre of excellence, integrated in the European Research Area. The objectives set by this project align with the EU SSH and digital agenda to expand the research and innovation potential, generate new knowledge, strengthen innovation and knowledge transfer activities, create industry driven projects and build capacity through combined academic-industry training, in close collaboration with local and global industry partners, support SSH informed evidence-based AI policymaking, develop key combined digital SSH competencies and produce interdisciplinary solutions to both societal and technological AI issues. In order to achieve its objectives, the newly created Centre will attract and maintain highly talented staff and PhD students under the direction of the proposed ERA Chair holder, while at the same time boosting the digital skills of existing staff and implementing structural changes necessary in the university to achieve a world-class and sustainable hub. Research excellence in this field will allow the University of Crete to participate in, and potentially lead, Research and Innovation across the commercial, cultural and social sectors, achieving high impact outcomes for science, academia and society at large. The University of Crete has committed to undertake all measures which will support the successful implementation of the project and its sustainability.

Keywords: hybrid ai,digital humanities and social sciences,datafication of education,knowledge graph,explainability,semantic web,lod,machine learning,natural language processing,standards,ontology
Future enabLing technologies for hYdrogen-powered Electrified aero engine for Clean aviatiOn (FlyECO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Clean and competitive solutions for all transport modes
Action type: Research and Innovation actions
Countries involved: Germany,France,Italy,Netherlands,United Kingdom
Call: Accelerating climate-neutral hydrogen-powered/electrified aviation (HORIZON-CL5-2023-D5-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 3496729.0
EU funding (EUR): 3496729.0
Participants: 6
Project status: SIGNED

FlyECO will deliver transformative technologies to support Integrated Power and Propulsion Systems (IPPS) that contributes to zero-emission and sustainable growth of aviation and has the potential to enable aviation climate neutrality by 2050. The utilization of hydrogen as sole energy source offers the opportunity to eliminate aviation CO2 emissions entirely. Furthermore, a reduction in NOx emissions of at least 50% is enabled by ingesting steam produced by a solid oxide fuel cell (SOFC) into the hydrogen-fuelled gas turbine (GT). FlyECO will develop a simulation and evaluation framework in which the optimal architecture definition of the IPPS, the key enabling integration technologies and necessary controls concepts can be explored, investigated closely and advanced towards TRL3 through Proof-of-Concept (PoC) demonstrators. A Commuter/Regional aircraft application was chosen as a use case to develop the propulsion system with more than one megawatt power. In particular, the energy management and distribution strategies will be developed for both quasi-steady-state and transient operation. In addition, PoC for the IPPS and the reduction in NOx emissions will be provided via two demonstrators: (1) a sub-structured test-rig emulating the cycle-integrated hybrid-electric propulsion system and (2) a high-pressure combustor with steam ingestion. The outcome of FlyECO will be comprise of: -An advanced simulation platform to analyse the impact of the SOFC integration on a hydrogen GT -A validation methodology for novel energy and power management strategies for the IPPS architecture -A controls approach for the IPPS, including specialised local control for components and subsystems as well as global control -A set of key coupling technologies develop developed to enable the integration of the SOFC with a GT under consideration safe design process in aviation based on ARP 4754A -An open-access database on hydrogen combustion with steam injection

Keywords: electrified aero engine hydrogen combustion fuel cell enabling technologies
City of Linköping FUTURE NOW - where ideas come to life (Future Now)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EU prize
Destination: European Capital of Innovation Awards
Action type: Recognition Prize
Countries involved: Sweden
Call: The European Capital of Innovation Awards Rising 2023 (HORIZON-EIC-2023-ICAPITAL-PRIZE-02, 2023)
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 1
Project status: SIGNED

Linköping is a city with an eye on the future. A city where world-leading research and ground-breaking innovations are creating a better future, where the university, the municipality, civil society and the business community work together to make innovative ideas become reality. Linköping, with 166,700 residents, is Sweden’s fifth largest city. Over the last decade, the number of residents has increased by almost 20,000, which makes Linköping one of the fastest growing cities in Sweden – and there are no signs of slowing down. Just like many other cities, Linköping faces a number of societal challenges. Meeting these challenges will take courage and innovative thinking in a close collaboration between the public sector, academia, the business community and civil society. Since 2001, the municipality has carried out its work according to the promise that Linköping is a place “where ideas come to life”, which means that we strive to create environments where people can thrive, grow and bring their ideas to life. In order to fulfill this promise, we must all work together towards a common goal. In this application, we highlight five of the biggest challenges that Linköping needs to address. Every specific area and success story we present below, is connected in one way or another to the identified societal challenges. Linköping has its sights set on transition to a greener, digital, more equitable future and strives to be a leader in promoting innovation and development to enable this transition.

Keywords: innovation,innovative city,sustainability,digitalisation,triple transition sme,ecosystem,experimenting,collaboration,new solutions,societal challenges,future,future now
Genetic code expansion for biocatalysis and enzyme engineering doctoral network (BiocatCodeExpander)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Netherlands,Austria,Spain,Czechia,Germany,United Kingdom,Canada,Sweden
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 2737212.69
EU funding (EUR): 2635624.8
Participants: 19
Project status: SIGNED

The expansion of the genetic code for the incorporation of non-canonical amino acids (NCAA) in proteins provides biotechnologists with an amazing kit of novel tools. NCAA can be used in multiple applications such as investigation of the structure and dynamics of proteins, as handles for protein imaging and spectroscopy, metal chelators or as click chemistry reagents. Yet, only a few cases exist where NCAA are used in enzyme engineering to explore, improve or install new enzymatic activities. Further development has been restricted by the limited efficiency and flexibility of tools for their incorporation. This is mainly caused by the field developing separately and not being driven by desired target catalytic activities and needs of protein engineers. Therefore, this DN proposal aims to bridge this gap and bring experts from different fields together to ensure the development of the methodologies in a collaborative manner. With a threefold- training structure Learn–Teach–Create, the DN trains 10 PhDs at the boundaries of biocatalysis, synthetic biology, peptide chemistry and computational biology and brings together a team of academic and industrial partners to increase the European research capacity. The efficiency and flexibility in NCAA incorporation are decisive for successful catalytic application; use of NCAA for selective protein conjugation facilitates application in site-selective immobilization; combination of protein folding analyses in high-throughput-screens with automatization fosters the application of NCAA in directed evolution to engineer reactivity and stability of enzymes; going a step further, NCAA can provide functional groups for designed biocatalysts for new-to-nature reactions. The proposed research affords new tools and applications, and the newly designed catalysts are envisioned to be important biotechnological processes for a greener, more environmentally friendly production of chemicals and pharmaceuticals.

Keywords: biocatalysis rational protein design directed evolution genetic code expansion non canonical amino acids novel enzyme design orthogonal protein conjugation
Asexual reproduction through clonal seeds: mechanisms to application (AsexualEmbryo)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Biotechnology and Biosystems E ngineering
Panel description: Biotechnology using all organisms , biotechnology for environment  and food applications, applied plant and animal sciences , bioengineering and synthetic biology , biomass and biofuels , biohazards
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-05-01
End date: 2028-04-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 2
Project status: SIGNED

Some plant species have abandoned sex and produce clonal seeds by apomixis; here, we will explore how this occurs, and exploit these insights to develop novel breeding technologies. In contrast to most eukaryotic species in which reproduction is sexual, a minority of plants and animals have evolved alternative – asexual – reproductive strategies. In plants, apomixis allows clonal transmission of favorable, hybrid genotypes through seeds over unlimited generations. Hybrid crop varieties are stress-resistant and high-yielding due to hybrid vigor, yet they reproduce sexually. The introduction of apomixis in hybrid crops would allow stable inheritance of hybrid vigor through seeds, in perpetuity, and eradicate the need to continuously re-make hybrids by crossing. However, our knowledge of the genetic and molecular basis of apomixis remains incomplete, and blueprints for synthetic apomixis in crops must be established. This project will decipher the function and evolution of a novel PARTHENOGENESIS gene that I recently demonstrated causes asexual embryo formation in naturally apomictic dandelions. Harnessing and extending fundamental findings, synthetic apomixis systems will be developed in two important vegetable crops – hybrid lettuce and tomato – allowing the full complement of hybrid traits to be faithfully inherited through seeds. Ultimately, apomixis in crops could revolutionize the €22 billion hybrid seed industry, make hybrid seeds readily available for all, and facilitate sustainable, high-performance agriculture around the world. Specifically, this project will involve: 1) Deciphering how a PARTHENOGENESIS gene homologue functions during sexual reproduction 2) Optimizing the expression of PARTHENOGENESIS factors through evolutionary insights and mutagenesis 3) Engineering synthetic apomixis – a holy grail of plant breeding – in two important dicot crop species by skipping meiosis and triggering PARTHENOGENESIS

Keywords: apomixis,clonal seeds,hybrid plants,meiosis,meiotic recombination,fertilization,plant chromosomes,plant biotechnology
Curing EU aquaculture by co-creating health and welfare innovations (Cure4Aqua)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Czechia,Croatia,Portugal,Greece,Spain,Germany,France,Poland,Switzerland,Chile,United Kingdom,Ireland,Denmark,Austria,Thailand,Belgium
Call: Biosecurity, hygiene, disease prevention and animal welfare in aquaculture (HORIZON-CL6-2022-FARM2FORK-01, 2022)
Start date: 2022-11-01
End date: 2027-04-30
Duration (months): 54.0
Total project cost (EUR): 4830623.76
EU funding (EUR): 4830613.75
Participants: 33
Project status: SIGNED

Farmed seafood is an important source of protein for food and feeds with a low-carbon footprint which has an important role to play in helping to build a sustainable food system. A strategic and long-term approach for the sustainable growth of a resilient EU aquaculture is, therefore, more relevant today than ever. However, the efficient and cost-effective control of pathogens remains among the main challenges for the sector, particularly relevant for Europe, where there is a great variety of species and production systems, which hinders the implementation of good husbandry practices tailored to each aquatic species. Through active engagement with key stakeholders, Cure4Aqua aims to jointly improve the resilience of EU aquaculture under environmental, biological, and socio-economic stress, by improving aquatic animal health and welfare and supporting the environmentally friendly, inclusive, safe, and healthy production of seafood. Cure4Aqua will do so by 1) developing cost-effective vaccines to prevent disease caused by 5 pathogens of economic significance to EU aquaculture; 2) Identifying markers with diagnostic capacity to be integrated to selective breeding programs to improve stress and disease management; 3) Developing innovative, bio-based and sustainable solutions as an alternative to antibiotics for controlling fish pathogens at various life stages and alleviate the pressure of global antimicrobial resistance; 4) Developing new tools and technology to improve health and welfare monitoring at the fish farm level and diagnostics of fish pathogens both at the laboratory and the fish farm levels; 5) Placing fish welfare at the foreground of aquaculture production, through the development of high welfare standards that consider different life-stages, production systems, and knowledge of welfare needs, and 6) Ensuring effective external communication, dissemination and exploitation of project activities and results to all relevant target groups.

Keywords: aquaculture pathogens co creation stakeholder engagement sustainable socio economics vaccines diagnostics epigenetics monitoring standards
The Milky Way system as a laboratory to understand the role of galactic winds in galaxy evolution (MW-WINDS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1026250.0
EU funding (EUR): 1026250.0
Participants: 1
Project status: SIGNED

Massive stars and black holes in galaxies work together to launch multiphase, gaseous winds at velocities of hundreds of kilometres per second. These galactic winds play a fundamental role in the evolution of galaxies, as they regulate the formation of new stars by transferring gas from the disk to the surroundings. Despite the recognised importance of these phenomena, the physical processes behind them and their actual impact on the life of different types of galaxies are still unclear, mainly because observations in external galaxies lack the spatial resolution to study in detail these winds and to constrain theoretical models. This ERC project will rectify this situation by using the Milky Way and its main satellites, the Magellanic Clouds, as the closest wind laboratories in the Universe. A unique and powerful combination of observational and theoretical techniques will be used for this project. New, high-resolution, multi-wavelength data from forefront telescopes will be exploited to explore the nature of multiphase material traveling within winds in different galactic environments with unprecedented accuracy, reaching sub-pc resolution in the Milky Way and pc resolution in the Magellanic Clouds. Observational measurements will be accompanied by advanced theoretical modelling and state-of-the-art hydrodynamical simulations, which will ensure the most accurate interpretation of the data and will provide new invaluable insights on the physics of galactic winds. This project will reveal 1) the detailed physical conditions of multi-phase gas in outflows, 2) the origin and physical mechanisms that drive these winds, 3) the connection with galactic environment, 4) the broader impact on the evolution of different host galaxies. These are all critical aspects to understand the role of galactic winds in shaping the galaxies that we see today. The outcome of this ground-breaking project has therefore the potential to add a key piece to the puzzle of galaxy evolution.

Keywords: galactic outflows,galactic centre,magellanic clouds,emission line observations
Stability Testing and Rapid Environmental Stress Simulation for Perovskite Photovoltaics (STRESS-PV)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-02-01
End date: 2028-01-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

To reach net zero by 2050 a 30-fold expansion in solar energy capacity is required, necessitating cheaper alternatives to Si semiconductors. Perovskite solar cells have power conversion efficiencies (PCEs) equivalent to the best Si cells and are inherently defect tolerant, meaning they are cheaper to manufacture than Si. Early perovskite technology was restricted by short operating lifetimes with most cells lasting only a few weeks rather than the 25 years required for commercial application. Recent advances have produced perovskite cells with negligible degradation after a year in the field, however. Thus researchers are turning to accelerated testing to quantify lifetimes and speed up stability improvements. Current accelerated testing uses 1-sun illumination and increased temperature to estimate lifetimes under normal conditions. Even under extreme temperatures this procedure requires several months to approximate 5 years in the field. To further speed up this process and expedite stability improvements I shall combine accelerated thermal degradation with accelerated photodegradation to reduce testing timescales to a matter of days. To achieve this, I will describe the decay modes of illumination based on spectral intensity and shape, and derive from them acceleration factors which relate back to outdoor testing results, thus deriving a protocol which mimics a decade of operation in only one week. Not only will this work expedite stability testing, but it will also explain how cells are damaged by light and which wavelengths. I will use these photo/thermal degradation insights to advance techniques for improved stability under light and heat. The project will conclude with an accelerated aging protocol used to demonstrate reproducible fabrication of > 20% PCE perovskite solar cells with estimated lifetimes of 10 years.
Timely detection of a potentially fatal chronic liver disease that one out of four of us have without knowing it. (LiverPRO)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Denmark
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-06-01
End date: 2024-05-31
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Evido is a health tech company that originates from the clinical world and stands on top of more than a decade of extensive clinical research from the elite Center of Liver Research at Odense University Hospital. We are a team of hepatologists, clinical researchers, data geeks, venture builders and healthcare innovators. All sharing a common goal to help people at risk of Chronic Liver Disease by re-inventing diagnostics with evidence-based and data-driven solutions. Our mission is to ensure timely detection and support of at-risk people that unknowingly have a potential fatal disease. We see the Women TechEU programme as a great opportunity that will front load our commercial traction and accelerate our time to market. Up to this point we have achieved to attract funding to cover our product development cost and regulatory affair. We have achieved to set up international collaborations to mature our data model and test our solution. All key activities to get LiverPRO to market and accelerate our adoption. To build on this traction and ensure a holistic perspective on our business, we want to broaden our activities and start frontloading our commercial activities already in the beginning of 2023. We see Women TechEU as a brilliant programme to support us in doing exactly this. Women TechEU can give us a resource boost to expand our focus and enable us to pursue commercial traction in parallel to getting LiverPRO to the market. We see a huge value in being part of the mentoring and coaching part of the programme and could really benefit from getting input on roll-out strategy, pricing, sales processes, pilot sales, etc. The combination of both financial support and specific coaching will help us accelerate our commercial traction and build a robust go-to-market strategy.

Keywords: health tech clinical decision support data driven timely detection healthcare innovation chronic liver disease fatty liver disease nash