Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
eVV - endoVascularVision: new endoscopic tools for real time vascular assisted vision (ENDO-VV)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,Belgium,Netherlands
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 1172442.0
EU funding (EUR): 1172442.0
Participants: 4
Project status: CLOSED

One of the main goals in endoscopic surgery is to improve reproducibility and safety by means of computer assisted systems to improve the surgeon’s vision. The main objective of this Transfer of Knowledge action is to conduct a common research programme leading to the development of new endoscopic assisted vision tools for real time enhanced identification of blood vessels (vascular vision). To this end, an intersectorial research programme is proposed, in which we will combine knowledge and expertise from two biomedical research groups with a company with high-level technological know-how in photonics. The project will structure the necessary transfer of knowledge to make possible the research needed to achieve the goals of the project. The medical groups will contribute with a high expertise in research models of endoscopic surgery, know-how in digital analysis of medical images, and a huge clinical workload allowing to test and refine the clinical solutions proposed. These will be combined with advanced technical support and the technologies recently developed within the biomedical company, to bring proof of principle models to real clinical tools. A common space for intersectorial research will be created. The programme involves an intensive component of bidirectional secondments of existing researchers together with new recruitments of experienced researchers to reinforce our skills in specific fields. The development of the technological solutions proposed will represent a major breakthrough in endoscopic imaging, with clear benefits to medicine and health technology. The solutions developed would find immediate applications in medicine, and the company is firmly interested in bringing innovations into current clinical devices. The proposed research would represent a significant increase for European RTD and the competitiveness of the groups and researchers participating in the programme.

Keywords: med.technology,med.sciences,diagnostics,gynaecology,obstetrics,surgery,applied optics,microscopy,applied electronics,molecular biophysics,biomedical engineering,health sciences,technological sciences
ultra-COLD gas for the production of a Bright Electron And Monochromatic ion Source (COLDBEAMS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,Italy,France
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-10-15
End date: 2014-10-14
Duration (months): 48.0
Total project cost (EUR): 964781.0
EU funding (EUR): 964781.0
Participants: 3
Project status: CLOSED

The objective of COLDBEAMS is to increase knowledge-sharing and mutual understanding between two Academic partners, Laboratoire Aimé Cotton (LAC), France and Dipartimento di Fisica of the Università di Pisa (UNIPI), Italy, and one SME, Orsay Physics (OP), France. The technical-scientific focus of this strategic partnership is on the development of a new electron and ion source based on ionized ultra-cold atoms. The use of this revolutionary incident source could create a real breakthrough in the Focused Ion Beams (FIB) or in energy electron source technology with substantial improvements in terms of monochromaticity, brightness and minimum spot size. The joint research project is designed to exploit complementary expertise of the participants and to create synergies between them. Orsay Physics is one of the leading companies in realization and commercialization of FIB and start to commercialized UHV focused electron beam columns, dedicated to surface analysis systems. Thus, the OP team should provide the partners the know-how on the ion/electron optics, electronics and industrial production requirements. OP will also provide the industrialization of a prototype and its commercialization. LAC from the Centre National de la Recherche Scientifique (CNRS), is the co-ordinateur of the project and, as the UNIPI, team is specialized in laser cooling of atoms. The LAC, is also specialist in ultra-cold plasma physics wheras the UNIPI is specialized on nanolithography through laser-cooled atomic beams. Thus, the LAC and UNIPI team should provide to OP the know-how on cold atom technology. The LAC team should develop the sources for Focused Ion and Electron Beams based on cold atom technology, why the UNIPI team should develop an ion source, but capable to be complementary to the LAC one, in particular develop a tool for the “single ion on demand” implantation.

Keywords: quantum chemistry,atomic physics,solid state physics,surface physics,experimental physics,electron-based nano-devices
Highly efficient new generation synthetic RNA-replicon based vaccine (REPLIXCEL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Switzerland,Germany
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-04-01
End date: 2014-03-31
Duration (months): 48.0
Total project cost (EUR): 2591172.0
EU funding (EUR): 2591172.0
Participants: 4
Project status: CLOSED

The project seeks to create a novel, efficacious vaccine against influenza virus; a new type of synthetic vaccine readily adaptable to meet whichever influenza virus subtype may arise. A new generation of RNA-replicon technology will be employed combined with nanoparticles and innovative adjuvants for targeting of dendritic cells and efficient antigen expression. The consortium comprises two SMEs and two academic institutions each having unique and patented expertise such as replicon technology, nanoparticle technology, adjuvant chemistry, and surface modification chemistry to attach targeting moieties. As a highly interdisciplinary project, extensive exchange of knowledge between the project partners will be required in particular between product focused SMEs (nanoparticles, adjuvants) and technology excellence of academic institutions (replicon technology, surface modification chemistry).

Keywords: vaccines,nanoparticles,surface modification,rna replicon,dendritic cell targeting
Drug Discovery in Interacting Proteins (DDIPI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ireland,Switzerland,United Kingdom
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-08-01
End date: 2014-07-31
Duration (months): 48.0
Total project cost (EUR): 643487.0
EU funding (EUR): 643487.0
Participants: 3
Project status: CLOSED

The Pharmaceutical sector is a mainstay of the European economy. However, changing patterns of drug discovery and competition has greatly enhanced the need for a SME sector to produce new drug leads and targets to feed big Pharma pipelines. This application addresses the need by coalescing partners involved in the identification/validation of new targets and in drug design, synthesis and discovery. The focus is on type 2 diabetes, obesity and immune diseases which cause serious disability and reduced life expectancy globally. Dualsystems and NUIM will be involved in the identification/validation of protein interactions involved in the pathway linking retinol binding protein and insulin, through which the former, when elevated in obesity, inhibits responses to the latter thereby contributing to type 2 diabetes. A second project will identify the protein machinery involved in the failure of otherwise active natural mutants of the MC4 receptor to traffic to the cell surface. This failure produces 6-7% of cases of gross genetic obesity. The third project will identify native protein ligands for a new family of G-protein coupled receptors (LNB-GPCRs), deeply implicated in immune-related diseases and cancer. The transfer of knowledge (TOK) involve development and use of yeast 2-hybrid systems to identify putative interactors and of rapid in vitro systems for interacting protein validation. A new yeast-based biosensor system will be advanced from “proof of concept” to the development stage. AFChemPharm focuses on new systems of chemical synthesis. They will work with NUIM on protein modelling, drug design, in silico screening and chemical synthesis to produce selected panels of compounds to screen for “hits” and to optimise into “leads. The TOK and skills acquisition will involve state of the art computational approaches in modelling, drug design and screening, together with their amalgamation with new synthetic processes to tailor/refine design and synthesis.

Keywords: natural sciences,technological sciences,membrane receptors,signalling pathways:protein modelling: in silico screening,drug design and synthesis,yeast 2 hybrid,yeast-based sensors
IAPP MeChanICs - Marie Curie linking Industry to CERN (MECHANICS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Finland,Switzerland,Finland
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 1026000.0
EU funding (EUR): 1026000.0
Participants: 8
Project status: CLOSED

The aim of Marie Curie linking Industry to CERN (MeChanICs) is to enhance knowledge exchange in the field of precision manufacturing. The project gathers five specialised precision manufacturer companies of excellence, of which one is an SME, to enhance their existing research and technology development (RTD) efforts with the University of Helsinki (UH) and CERN. The mechanisms used for the transfer of knowledge within MeChanICs are two-way intersectoral secondments and dissemination workshops. MeChanICs will be established within the UH’s existing research cooperation with the CERN-led Compact Linear Collider (CLIC) technology development, one of the highlighted topics of the European Strategy for Particle Physics. CLIC is likely to represent the forefront of Particle Physics in the post-Large Hadron Collider (LHC) era and its development boosts the competitiveness of its suppliers by pushing the used technologies to their limits. Close co-operation with industry in the next years is vital to devise an industrialisation scheme enabling the mass manufacturing of the required components at an affordable price and on time for a decision on the future direction of Particle Physics based on the LHC results. From the perspective of European industry, CLIC represents major technological challenges, possibilities for long-term RTD collaboration as well as significant future commercial opportunities, especially as CLIC technologies already show potential beyond Particle Physics applications, notably for X-ray free electron lasers and hadron therapy. The project strongly supports the on-going international RTD projects in machining and in precision assembly. MeChanICs widens the precision manufacturing value chain by also comprising RTD in brazing, materials and design. In addition, MeChanICs contributes to the objectives of the MoU between the EC and CERN on further developing the European Research Area, particularly concerning researcher training and mobility.

Keywords: precision manufacturing,particle physics,big science,machining,brazing,assembly,materials,intersectoral rtd collaboration,sme,industrialisation,mass production
The Commercialisation of Transglutaminase. (TRANSCOM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Finland,Hungary,France,Finland,United Kingdom
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-07-01
End date: 2014-06-30
Duration (months): 48.0
Total project cost (EUR): 1680248.0
EU funding (EUR): 1680248.0
Participants: 7
Project status: CLOSED

The TRANSCOM project is designed to facilitate the exchange of knowledge and technology between 3 leading European research teams and 4 SMEs each with an interest in the protein crosslinking enzymes Transglutaminases. Transglutaminases are a widely distributed group of enzymes that catalyse the post-translational modification of proteins by the formation of isopeptide bonds or by deamidation of proteins. The deregulation of enzyme activity generally associated with major disruptions in cellular/tissue homeostasis can result in a number of human diseases TRANSCOM will be involved in the invention, development and production of diagnostic kits and treatments for health problems related to the activity of transglutaminases. The project will establish the molecular nature of the role of transglutaminases in the pathogenesis of diseases such as coeliac disease, neurodegeneration and intravenous catheter infections which are known to involve their cross-linking activity. The proposed work programme will develop new knowledge to address gaps in our understanding of this field and transfer existing knowledge and skills between sectors. It will build and broaden the capability of the partners with the objective of accelerating the development of new strategies that can be used in diagnosis and treatment of coeliac disease, neurodegeneration and in the prevention of infections like MRSA associated with intravenous catheters.

Keywords: natural sciences cell biology,biochemistry,molecular biology
Advanced Myoelectric Control of Prosthetic Systems (AMYO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria,Denmark,Germany,Germany,Italy
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 1152406.0
EU funding (EUR): 1152406.0
Participants: 6
Project status: CLOSED

In spite of decades of research and many capabilities and potentials as well as incremental improvements, advanced human-maschine interfaces based on the electromyogram (EMG) still have a significant distance from professional and commercial applications. This is also and particularly true for myoelectric prosthetic devices. Available commercial myoelectric control systems for prostheses can only control one single degree-of-freedom at a time. However, there is a great need for improved myoelectric control systems. The proposed project will combine European academic excellence in EMG signal processing and pattern recognition, industrial expertise in EMG acquisition, and the clinical and industrial expertise of the market leader in prosthetics. The objective of the proposal is to advance myoelectric control systems that allow simultaneous and intuitive control of several degrees of freedom.

Keywords: electromyography,prosthetics,myoelectric control,signal processing,pattern recognition,machine learning
SOPRA-FORTH Partnership for the Development of a Microsecond Ellipsometer (SOFORT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Greece,France,United Kingdom
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-08-01
End date: 2014-07-31
Duration (months): 48.0
Total project cost (EUR): 494135.0
EU funding (EUR): 494135.0
Participants: 3
Project status: CLOSED

The FORTH’s team has recently demonstrated an extremely fast and sensitive ellipsometer, based on the amplification of the ellipsometric angle by multiple reflective passes (at least 100 and as many as a million) at the interface in question. It is able to make senstive measurements on timescales as fast as microseconds (at least), with applications including biosensing, microelectronics, and surface dyanmics. The FORTH research effort will be integrated with a larger research activity funded by an ERC Starting Grant (TRICEPS), which focuses on the development of basic scientific principles of cavity-enhanced metrology. The scientific and technological aim of the project is to investigate the commercial viabilty of the new ellipsometric techniques, and it&apos;s use to probe a range of time-dependent surface phenomena, with unprecedented time resolution and sensitivity. The proposed collaboration will be fruitful for both parties for the following reasons: a) The IESL-FORTH team has demonstrated a very promising technique (in the field where SOPRA is a world leader), but lacks experience in commercial instrument development. The research and product development is best done in conjunction with a leading company with experience with similar successful products. b) The new technique will substantially enhance the time-resolution of the classical ellipsometer by orders of magnitude (down to microseconds at least) and nonetheless remain technically simple. It will also be applicable to a new range of research, and will appeal to a wider client base, which of interest to SOPRA. c) IESL-FORTH will benefit from interaction with an industrial partner, by gaining experience in how a product should be developed, and learning about the problems that such development entails. SOPRA will benefit from contact with academic research by learning about new applications outside of its existing field of expertise.

Keywords: applied optics,instrumental techniques
Compressed Sensing for Remote Imaging in Aerial and Terrestrial Surveillance (CS-ORION)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Greece,France,France
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 1292270.0
EU funding (EUR): 1292270.0
Participants: 4
Project status: CLOSED

In this project, our focus is on the design, testing, and evaluation of compressive sensing (CS) architectures for enhancing the high-quality video acquisition and delivery capabilities of remote sensing devices that will enable them to provide efficient remote imaging in aerial and terrestrial surveillance. We will address limitations to current video coding methods which restrict the use of remote sensing devices to offering only a low-quality streaming video to the user. In order to overcome these limitations, novel algorithms which go well beyond the currently developed techniques and standards are needed. Equally importantly, the proposed methods must be developed with the hardware constraints of the platform of operation in mind, including restrictions regarding computational, memory, and power consumption, as well as the available reserved bandwidth. The proposed activities are designed in order to address these challenges. An important aspect of this project is the conscious exploitation of the inherent encryption of the signal that the compressive sensing methodology offers. We intend to use this property to enrich the signal intelligence capabilities of surveillance systems. The proposed consortium consists of partners with complementary expertise which covers all the involved research areas, from the point of capturing the video imaging content to the point that it is dynamically reconstructed and analyzed through CS reconstruction techniques by the user.

Keywords: remote imaging,image and video coding,compressed sensing,surveillance techniques.
Computational Intelligence Platform for Evolving and Robust Predictive Systems (INFER)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany,Poland
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-07-01
End date: 2014-06-30
Duration (months): 48.0
Total project cost (EUR): 1555380.0
EU funding (EUR): 1555380.0
Participants: 4
Project status: CLOSED

The proposed research programme will focus on pervasively adaptive software systems for the development of an open modular computational INtelligence software platform For Evolving and Robust predictive systems (INFER) applicable in various commercial settings and industries. The main innovation of the project is a novel type of environment in which the “fittest” predictive model for whatever purpose will emerge – either autonomously or by user high-level goal-related assistance and feedback. The application of the INFER platform as smart adaptive soft sensors will contribute to increasing the operational excellence of the European process industry represented by a large international company, Evonik Degussa GmbH from Germany, focusing on specialty chemistry. The jointly developed software platform will translate the latest academic research results achieved with help of the academic partner, Bournemouth University from UK, into a commercial software product through involvement of highly skilled and innovative SME software company, Research &amp; Engineering Centre from Poland. In facilitating a continuous exchange of expertise, firstly by including new and innovative ideas in actual industry products and services and secondly by providing constant feedback in terms of practical applicability of the new approaches and future needs and requirements, a long-term research collaboration and mechanisms for commercial exploitation of research results will be established. The partners believe that engineering of more robust, context aware and easy-to-use ICT systems, which improve, adapt and maintain themselves within their respective environments and constraints, will play a crucial role in removing various technological roadblocks and reinforcing Europe’s industrial and commercial strengths.

Keywords: computational intelligence,predictive systems,intelligent data analysis,process industry,soft sensors,software engineering,complex systems,meta-learning,learning and adaptation