Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Developing the Croatian Underwater Robotics Research Potential (CURE)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Croatia
Call:  (FP7-REGPOT-2008-1, 2008)
Start date: 2009-04-01
End date: 2012-03-31
Duration (months): 36.0
Total project cost (EUR): 1074840.0
EU funding (EUR): 959049.0
Participants: 1
Project status: CLOSED

The project aims at reinforcing the Croatian S&T potential in underwater robotics (underwater systems & technologies) through a coherent set of measures. Measures are focused toward: supporting and mobilization of human and material resources; developing strategic partnerships with well known research centers in EU; dissemination of scientific information and research results; facilitating communication between UNIZG-FER Laboratory for underwater systems and technologies (LabUST), and research entities having similar scientific interests in EU and also other stakeholders in the region; improve LabUST responses to socio-economic needs of the country and region especially related to Adriatic Sea. The ultimate goal of CURE is to prepare ground for R&D integration of the LabUST into the FP7 program. Integration may find its way in terms of R&D proposals, scientific cooperation or business contacts based on technological innovation. The project will also create additional visibility and impact for running projects in creating and supporting relevant public relations (PR) so as to facilitate dissemination, transfer and exploitation of project results, stimulate and encourage the participation of regional organizations in the EU R&D program. To ensure the project’s objectives, work packages (WP), tasks (T) and deliverables (D) have been carefully planned according to call objectives. Work packages have clearly defined timing and impact. Expected impacts are in upgrading the RTD capacity and capability i.e. the human potential, the number of new researchers and training of research staff, improvement of research management, strengthening the research infrastructure and the quality of research, enabling better integration in the ERA. Partnership with research groups in EU will contribute to regional capacity building and will improve LabUST underwater robotics research potential.

Keywords: underwater robotics,unmanned underwater vehicles,underwater systems,underwater technology,remotely operated vehicles,autonomous unmanned vehicles,marine vessels.
South Moravian Programme for Distinguished Researchers (SOMOPRO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Czechia
Call:  (FP7-PEOPLE-2007-2-3-COFUND, 2007)
Start date: 2009-04-01
End date: 2013-12-31
Duration (months): 57.0
Total project cost (EUR): 3584494.65
EU funding (EUR): 1433797.86
Participants: 2
Project status: CLOSED

In 2007, the Region of South Moravia provided two ad hoc grants for the regional Masaryk University, which enables the university to host two high level foreign researchers. With the emergence of COFUND it was suggested to create a regional funding scheme to support transnational mobility of researchers in the whole region. The funding scheme will build on high technological standard and high quality research of the region and will aim at advancing the quality by increasing international migration of human resources in science and technology which was up till now quite low particularly due to insufficient financial resources. Increase in internationalization of the regional research will bring new contacts, knowledge and technologies and will help to boost efficiency of the research activities. The main aim of the proposed fellowship programme is to build on other regional activities and projects in the field of R&D and innovation and enhance their effect by: a/ attracting top-class foreign researchers to work and undertake research training in the region from 1 to 3 years, with a view to developing mutually-beneficial research co-operation. b/ provide financial assistance to researchers who wish to return and find a job in the region after they have worked in research in a Third country for at least three years. The duration of these grants will be from 1 to 3 years. The SoMoPro programme will provide career development and training for fellows. The coordinator of the fellowship programme shall be the Region of South Moravia which shall appoint the South Moravian Centre for International Mobility to be in charge of certain parts of the administration of the fellowship programme.

Keywords: fellowship programme,incoming mobility,reintegration,selection,career development,life scienses,material scienses
Collective Phenomena in dense Active Matter: phase transitions and non-equilibrium dynamics. (COLPHAM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-07-15
End date: 2017-08-13
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

The overall aim of the research activities presented in this proposal is to elucidate the general principles governing the physics of many-body systems of active particles when excluded-volume interactions compete with internal driving forces. We aim to reach a general understanding of this novel class of “active materials” and give an answer to the following question: How are the structure of the liquid and solid phases, and their mechanical response to an applied deformation, affected by self-propulsion? Statistical mechanics can efficiently deal with a broad class of soft matter systems at thermal equilibrium. However, active matter evolves in a non-equilibrium manner, as it is made of elements which have their own source of motion, which demands a new conceptual framework to describe it. By combining numerical simulations and theoretical analysis of model systems, we intend to get new quantitative predictions that can be tested experimentally in suspensions of self-propelled colloids, active emulsions or dense assemblies of cells, and exploit our results to design and characterise novel materials through collaboration with experimental groups. The completion of this programme will represent a major contribution into this fast-growing field with direct applications in materials science and biophysics: the engineering of synthetic materials that mimic the behaviour of living matter is a major challenge of current science and technology.

Keywords: soft active matter,self propelled particles,numerical modeling,microswimmers,complex liquids,amorphous solids,rheology,mode coupling theory
Hybrid simulations of flow properties using atomistic – fluctuating hydrodynamics modelling for nanoconfined water (HIPPOGRIFFE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-07-01
End date: 2018-06-30
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The goal of this Marie Curie Individual Fellowship, entitled “Hybrid simulatIons of flow ProPerties using atOmistic – fluctuatinG hydRodynamics modellIng For nanoconFined watEr” (HIPPOGRIFFE) is to train a talented Experienced Researcher (ER), Dr. Ivan Korotkin through a research project focused on the development of novel multiscale modelling methods, which offer a unique tool for guiding the high-resolution measurements at nanoscale. The properties of nanoconfined water, such as density, the structure of hydrogen bonded network, local temperature, translational and rotational diffusions, and effective viscosity can be very different in comparison with the bulk water properties. These differences must be understood and accounted for if the high-precision measurement techniques such as atomic force microscopy (AFM) are to be used in confidence for nanoscale imaging and control of interfacial and nanoconfined liquid flow. The ER will be trained in the field of multiscale modelling and manipulation of nanoconfined flows. He will receive access to a unique specialist training at the host institution, School of Engineering and Materials Science, Queen Mary University of London (Dr. S. Karabasov), and at academic secondments: Aston University (Dr. D. Nerukh), Universidad Autónoma de Madrid (Prof. R. Delgado Buscalioni), and Durham University (Dr. K. Voïtchovsky). The results of the HIPPOGRIFFE project will contribute to the enhancement of scientific excellence in European research. The results of the project will also find their ultimate use in industry, e.g. through providing recommendations for refined applications of the AFM technology for nanoscale imaging and developing new computational routines for the software companies who specialise in multiphysics modelling. In addition, the project will establish long-term collaborative relations between the multiscale modelling centres (Queen Mary, Aston, AUM) and the centre of nanoscale manipulation of liquids (Durham).

Keywords: multiscale modelling,molecular dynamics,hydrodynamics,atomic force microscopy,nanofluidics
Neuronal Alternative Splicing and RNA-Editing Crosstalk (NeuroASPECT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-09-01
End date: 2019-08-31
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

A long-standing question in biology has been to determine how the mammalian central nervous system (CNS) achieves its dramatic cellular complexity and connectivity. Notably, mechanisms increasing transcript diversity, particularly alternative splicing (AS) and RNA-editing, have critical roles in the mammalian CNS development and function. However, it is still unclear whether the crosstalk between these two processes constitutes an additional RNA-mediated regulatory layer contributing to the complex mammalian CNS. Thus, the main goal of NeuroASPECT is to determine the extent, dynamics and functional relevance of the crosstalk between AS and RNA-editing in the mammalian CNS. To tackle this general goal, I propose the following specific aims: 1) Elucidate the extent of co-regulation between AS and RNA-editing events in the CNS by building a comprehensive catalog of neural co-regulated AS-editing events in mammals and explore their evolutionary conservation in other vertebrates. 2) Assess the crosstalk between AS and RNA-editing in neural differentiation by analyzing transcriptomes of cells with impaired RNA-editing. 3) Characterize the functional impact of AS and RNA-editing crosstalk on mouse neurogenesis. I expect this work will uncover RNA networks established between AS and RNA-editing that are involved in shaping and regulating the CNS transcriptome. Moreover, it will also contribute to a better understanding of the biological functions and regulation of AS and RNA-editing, in both an independent and synergistic manner. In addition, the functional characterization of the AS-editing crosstalk could ultimately reveal alterations in which the lack of coordination between AS and RNA-editing can lead to the development of neurological disorders, thus offering potential targets for their treatment.

Keywords: alternative splicing,rna editing,central nervous system,mammals
HeAlth Regulation by the gut Microbiota in the Honey bee (HarmHoney)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-05-01
End date: 2022-10-27
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: CLOSED

When feeding on plants, animals ingest non-nutritive compounds produced by the plant which are converted by the metabolic activity of bacteria present in their gut and act on their physiology. Some of these phytochemicals, the flavonoids, provide health benefits in many species, but little is known about the modulation of their bioactivity by the gut microbiota. Here, we want to understand the importance of the gut microbiota in modulating flavonoids' effects on honey bee health under physiological conditions and after exposure to neonicotinoid pesticides. Honey bees are vital pollinators to our ecosystem and the current decline in their population is alarming. The neonicotinoids have been identified as one of the responsible factors. Using 16S rRNA sequencing and metabolomics approaches, we aim at identifying the combinations of flavonoids and gut symbionts promoting bee health and resistance to neonicotinoids. Bee health will be assessed both under laboratory and field conditions by measuring the survival rates, the activity of the detoxification pathway and the maturation speed because stressed bees have been shown to start foraging younger than healthy bees. The outcome of this project will be of interest for a large range of scientific communities from microbiologists to ecologists, both in fundamental and applied sciences. Promoting health by acting on diet and gut bacteria is a hot topic, as is the decline in bee populations. Dissemination of the results to the general public will be facilitated by the existing enthusiasm for these questions. The applicant will share her knowledge of the honey bee physiology and behavior with the host laboratory and will gain from its expertise in gut microbiota function. She will acquire the skills necessary to apply for junior researcher positions at the end of the fellowship and to focus her career on the importance of the gut microbiota and diet for honey bee health, both at the physiological and behavioural level.

Keywords: phytochemicals,pesticides
Killer plasmids as drivers of genetic code changes during yeast evolution (CODEKILLER)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Ireland
Call: ERC Advanced Grant (ERC-2017-ADG, 2017)
Start date: 2018-10-01
End date: 2025-03-31
Duration (months): 78.0
Total project cost (EUR): 2368356.0
EU funding (EUR): 2368356.0
Participants: 1
Project status: SIGNED

The genetic code was established at a very early stage during the evolution of life on Earth and is nearly universal. In eukaryotic nuclear genes, the only known examples of a sense codon that underwent an evolutionary change of meaning, from one amino acid to another, occur in yeast species. The codon CUG is translated as Leu in the universal genetic code, but it has long been known to be translated as Ser in some Candida species. In recent work, we discovered that this switch is one of three parallel reassignments of CUG that occurred in three closely related clades of yeasts. CUG was reassigned once from Leu to Ala, and twice from Leu to Ser, in three separate events. The meaning of sense codons in the nuclear genetic code has otherwise remained completely stable during all of eukaryotic evolution, so why was CUG so unstable in yeasts? CODEKILLER will test a radical new hypothesis that the genetic code changes were caused by a killer toxin that specifically attacked the tRNA that translated CUG as Leu. The hypothesis implies that the reassignments of CUG were not driven by selection in favor of their effects on the proteome, as commonly assumed, but by selection against the existence of a particular tRNA. As well as searching for this killer toxin, we will study the detailed mechanism of genetic code change by engineering a reversal of a CUG-Ser species back to CUG-Leu translation, and investigate translation in some species that naturally contain both tRNA-Leu and tRNA-Ser molecules capable of decoding CUG.

Keywords: trnas,selfish genetic elements,genetic code,translation
Unveiling the population of supermassive black hole binaries near merger (UnveilingBlackHoles)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-04-01
End date: 2023-03-31
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: SIGNED

At the center of nearly every galaxy in the Universe lurks a supermassive black hole with mass millions to billions that of the Sun. When two galaxies collide, their supermassive black holes sink to the center of the newly forming galaxy. There in this nascent galactic nucleus a supermassive black hole binary is formed. Supermassive binaries are the subject of a long standing mystery in astrophysics: will these monstrous black holes merge and what can that tell us about the extreme environments that shape them? I will make great strides towards solving this mystery through advancing the state of the art in simulations of interactions of supermassive black hole binaries and their gaseous environments. From these simulations I will predict binary orbital evolution rates as well as observational signatures of the interaction. I will use the former to build the most accurate binary population models to date and the latter to constrain these models via observational searches in the newest time domain data, possibly leading to the first detections of these elusive black hole pairs.
Novel Dark Matter Searches with Top Quarks at the Large Hadron Collider (LHCDMTOP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-05-01
End date: 2020-04-30
Duration (months): 48.0
Total project cost (EUR): 1584650.0
EU funding (EUR): 1584650.0
Participants: 1
Project status: CLOSED

This project will address directly the two most important unanswered questions in particle physics: the Standard Model (SM) hierarchy problem and the nature of dark matter (DM). The SM was recently completed with the discovery of the Higgs boson at the Large Hadron Collider (LHC) in 2012. We know, however, that the SM cannot be the end of the story for fundamental physics, because it suffers from two major flaws: a lack of stability for the mass of the Higgs boson (the hierarchy problem), and a lack of a candidate for the invisible DM particles known to make up most of the matter in the universe. I will address both of these key problems of modern physics by searching at the LHC for new beyond the SM (BSM) partner states for the SM top quark decaying to new DM particles. The greatly increased quantities of data and world-record collision energies generated by the LHC in the next three years will provide an unprecedented opportunity to find such top partners. Confirmation of their existence would solve the hierarchy problem by providing a mechanism for stabilising the mass of the Higgs boson, while first observation of DM at the LHC would revolutionise our understanding of cosmology and provide a key pointer to the physics of the very early universe. Many leading BSM physics models predict the existence of both top partners and DM, and so this interdisciplinary project provides a unique opportunity to take the next major step forward in developing a unified theory of nature. I will focus on top partners which decay to a top quark and a DM particle, with the former decaying purely to jets and the latter escaping the detector unseen. I will use novel kinematic techniques developed by me to identify and characterise this signal in LHC data, and also accurately measure for the first time the dominant SM background process of associated production of top quarks and a Z boson, which is of great theoretical interest in its own right.

Keywords: supersymmetry pacs2010 12 60 jv,14 80 ly,dark matter pacs2010 95 35 d