Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
SAFE AND FLEXIBLE INTEGRATION OF ADVANCED U-SPACE SERVICES FOCUSING ON MEDICAL AIR MOBILITY (SAFIR-Med)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Germany,Germany,Cyprus,Greece,Belgium,Switzerland,Belgium,France,Czechia,Netherlands,Netherlands
Call: U-space capabilities and services to enable Urban Air Mobility (H2020-SESAR-2020-1, 2020)
Start date: 2020-12-01
End date: 2023-03-31
Duration (months): 28.0
Total project cost (EUR): 2725120.0
EU funding (EUR): 2038609.01
Participants: 17
Project status: SIGNED

The SAFIR-Med project’s vision is to achieve safe, sustainable, socially accepted and socially beneficial urban air mobility. SAFIR-Med represents all value chain actors and stakeholder as either project partner (ATC, USPs, Operators, UAS Manufacturers, cities) or formal associate partner (major customers, technology & service providers) at a representative international level. Five unmanned UAV platforms (passenger eVTOL, Hydrogen fuel cell VTOL, AED medical drone, X8 medical transport) will be combined with manned aviation in real life exercises validating technology in real urban environment. Technologies of all partners will be leveraged to make use of the maximum number of U-Space services towards the highest possible operational safety level, including advanced Detect And Avoid U-space service. The demonstrations will take place in the cities of Antwerp (BE), Aachen (DE) and Heerlen (NL), leveraging the MAHHL trans-border region, following a full de-risking exercise at the DronePort BVLOS test-facility in Sint-Truiden, Belgium. The demonstration results will be further virtually enhanced through large-scale simulations in order to test the maximum airspace capacity of the CONOPS. The project results will then further be validated and made representable for the whole of the EU, by simulating demonstrations in two additional locations in Europe, namely Athens, Greece (South EU) and Prague, Czech Republic (East EU). Lessons learnt will be documented in a Performance Assessment and recommendations report, providing refinements to the current U-space architecture principles and creating measurable indicators for UAM which will enable Smart Cities to include UAM in their Transport Roadmaps, support standardisation and thereby safety. Finally, SAFIR-Med will have made an important contribution to the EU healthcare system, by ensuring that future generations will continue to democratically have access to the best cure and care.

Keywords: u space services demonstration,detect and avoid,tracking,passenger drone
Lightning inhibition for protection of urban soft targets and critical infrastructure against lightning strikes. (LightningPro)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Spain
Call: Engaging SMEs in security research and development (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-07-01
End date: 2016-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Since 1752, when Benjamin Franklin carried out his famous experiment with a kite, science has not gone much further in protection agains. Lightning strikes. Lightning Rod manufacturers have centered attention in obtaining maximum benefit from the so named Franklin–Rod, developing devices with greater lightning attraction to try to maximize the probability that the lightning will strike on it. Prototal has gone one step forward, developing the Inhibitor Lightning Rod to provide infrastructure and urban areas protection against lightning strikes, by means of a primary protection element, which impedes the creation of the conditions that produce a lightning strike, within the protected area. The Inhibitor Lightning Rod deionizes the environment, so the beam is not repelled elsewhere, but it simply doesn’t get formed; the beam formation is inhibited. Our company, has been working in the sector of lightning protection since 1993. We have installed more than one thousand Inhibitor Lightning Rods with the 100% of success rate against lightning strikes. Currently, we want to develop a second generation of our product, having a bigger coverage area, a better design, reducing the cost of manufacturer process and including technical tests that confirm our technical specifications and clients’ requirements.

Keywords: lightning rod,inhibitor lightning rod,nanomaterials
Biofunctionalised Electroconducting Microfibres for the Treatment of Spinal Cord Injury (Neurofibres)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Emerging themes and communities
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Spain,Sweden,France,France,United Kingdom
Call: FET Proactive: emerging themes and communities (FETPROACT-2016, 2016)
Start date: 2017-01-01
End date: 2021-06-30
Duration (months): 54.0
Total project cost (EUR): 5888491.25
EU funding (EUR): 5094120.0
Participants: 7
Project status: CLOSED

Bio-electronic microsystems hold promise for repairing the damaged central nervous system (CNS). However, this potential has not been developed because their implantation inflicts additional neural injury, and ensuing inflammation and fibrosis compromise device functionality. In Neurofibres we want to achieve a breakthrough in “Neuroregenerative Bio-electronics”, developing dual-function devices that will serve as electroactive scaffolds for CNS regeneration and neural circuit activation. We engineered electroconducting microfibres (MFs) that add negligible tissue insult while promoting guided cell migration and axonal regeneration in rodents with spinal cord injury (SCI). The MFs also meet the challenge of probe miniaturisation and biofunctionalisation for ultrasensitive recording and stimulation of neural activity. An interdisciplinary consortium composed of neuroscientists, medical specialists, researchers in biomaterials, protein engineering, physics, and electrical and mechanical engineering, together with a company specialised in fabrication of microcables and microconnectors, will join efforts to design, develop, and test the MFs and complementary technology (microfibre functionalisation, assembling, and electronic interconnection), in order to produce a biologically safe and effective bio-electronic system for the treatment of SCI. This goal will be achieved through five specific objectives: 1) To improve the electrical conductivity, strength, and chemical stability of the microfibres. 2) To develop electro-responsive engineered affibodies for microfibre functionalisation. 3) To develop the technology for MF interconnection and assembling into implantable systems. 4) To perform comprehensive investigation of the immunological, glial, neuronal, and connective tissue responses to the implanted MFs and applied electrostimulation in rodent and swine SCI models. 5) To investigate the motor and sensory effects of microfibre implantation and electrostimulation.

Keywords: bio electronic systems,microfibres,electroactive scaffold,conducting polymers,graphene,affibody engineering,neuron,glia,spinal cord injury,neural repair,intravital microscopy,rodents,pigs
Exploiting low dimensional models in sensing, computation and signal processing (C-SENSE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-09-01
End date: 2022-08-31
Duration (months): 72.0
Total project cost (EUR): 2212048.0
EU funding (EUR): 2212048.0
Participants: 1
Project status: CLOSED

The aim of this project is to develop the next generation of compressive and computational sensing and processing techniques. The ability to identify and exploit good signal representations is pivotal in many signal and data processing tasks. During the last decade sparse representations have provided stunning performance gains for applications such as: imaging coding, computer vision, super-resolution microscopy and most recently in MRI, achieving many-fold acceleration through compressed sensing (CS). However in most real world sensing it is generally not possible to fully adopt the random sampling strategies advocated by CS. Systems are often nonlinear, measurements have limited dynamic range, noise is rarely Gaussian and reconstruction is not always the final goal. Furthermore, iterative reconstruction techniques are often not adopted in commercial imaging systems as they typically incur at least an order of magnitude more computation than traditional techniques. Thus there is a real need for a new framework for generalized computationally accelerated sensing and processing techniques. The research proposed here will build on the PIs recent work in this area and will develop and analyse a much richer class of hierarchical low dimensional signal models, accommodating everything from physical laws to data-driven models such as deep neural networks. It will provide quantitative guidance for system design and address sensing tasks beyond reconstruction including detection, classification and statistical estimation. It will also exploit low dimensional structure to reduce computational cost as well as estimation accuracy, challenging the notion that exploiting prior information must come at a computational cost. This research will result in a new generation of data-driven, physics-aware and task-orientated sensing systems in application domains such as advanced radar, CT and MR imaging and emerging sensing modalities such as multispectral time-of-flight cameras.

Keywords: compressed sensing,low dimensional signal models,high dimensional statistics,computational complexity
A pH-Responsive Bionanohybrid Nanofibrous Wound Dressing (SNFWD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-08-01
End date: 2021-07-31
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: CLOSED

To address the dynamic nature of wound healing, the wound care market is transitioning from classic protective barriers into advanced, active wound dressings, interacting with the wound by stimulating and managing cell migration and the sequence of healing events. In this regard, development of smart drug delivery wound dressings based on nanofibers, is a novel topic and of high importance due to the porosity, biomimicry and high surface area of such materials bringing about very optimum oxygen and water permeability, enhanced cell activity thus healing rate and better dissolution rate and ease of incorporation of drugs, respectively. However, to industrially realize such systems, there are still some challenges. Of the most important challenges is fabrication approach of such systems, that must not lead to either a burst release or damage to the drug during the process. As a novel idea, I aim to biomineralize a doped calcium phosphate drug carrier coating on the surface of nanofibers that could be efficiently loaded by drug molecules through electrostatic interactions. To accelerate the healing rate of chronic wounds, the wound medium is conventionally acidified by topical application of acids. This synthetic acidification along with natural trend of acidification of the wound as far as healing continues, can lead to dissolution of the drug carrier coating, thus release of drug molecules in a controlled manner. In this nanofibrous wound dressing, not only the nanofibrous structure biomimicking natural extracellular matrix of human tissues and smart drug delivery facilitates interaction with live cells and manages the healing process, respectively, but also cheap and fast electrospinning process for production of nanofibers promise an industrially adaptable approach. Thus, this proposed research would be an important novel step towards introduction of nanofibrous drug delivery wound dressings to industry.
Re-making the World: Women, Humanitarian Agencies and Handicrafts Programmes (ReMTW)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2023-09-30
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: TERMINATED

The First World War threatened to extinguish the renowned Belgian lace industry, cut off from both markets and raw materials. Thousands of female lacemakers would be left without an income. Humanitarian organisations stepped in, saved the country’s cultural heritage, and supported its workers by supplying materials and selling the finished fabrics. Their actions gave unprecedented publicity to the industry and employed more than 50.000 Belgian lacemakers. The produced lace became known as war lace, as its unique iconography sometimes referred directly to the conflict. Art historians and craft practitioners addressing war lace have concentrated on high-quality laces designed by recognised artists. Historians have tended to study food and medical aid programmes. Yet the history of such humanitarian handicraft programmes remains obscure. ReMTW fills this gap. It uncovers the overlooked origins for the preservation of cultural heritage by humanitarian organisations, while examining the prospect for female emancipation and artistic expression. Through a combination of archival, collection and practice-led inquiry, the project will lead to an innovative history of humanitarianism which encourages historians to attend to material object, and art historians and craft practitioners to engage with the historical processes and the production of embodied knowledge. During the fellowship, the ER will organise an international colloquium, submit 3 peer-reviewed articles, present 2 papers at international conferences and lead an interdisciplinary workshop with 3 site-specific iterations. This will enhance the ER’s skills and future employability prospects, by opening new training opportunities, furthering her ability to plan, organise, and develop her dissemination and public outreach competencies, and reinforcing her professional international networks of researchers and practitioners versed in history, art history and craft practice.

Keywords: craft,needlework,textiles,material culture,first world war,humanitarianism,refugees,transnational,belgium,lace,cultural diplomacy,civic diplomacy,charity market,cultural nationalism
Metabolism of DNA secondary structures and their impact on genome stability (MetDNASecStr)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-05-01
End date: 2021-04-30
Duration (months): 72.0
Total project cost (EUR): 1638041.0
EU funding (EUR): 1638041.0
Participants: 1
Project status: CLOSED

DNA replication is an essential process for genome duplication, cell division and ultimately organismal survival that ensures faithful transmission of the genome to progeny. Certain genomic loci represent major obstacles to DNA replication including fragile sites, G-rich tracts and repetitive sequences, such as ribosomal DNA and telomeres. Mammalian telomeres have the propensity to adopt complex DNA secondary structures, including telomere-loops and telomeric G-quadruplex DNA, which are believed to play essential roles in telomere maintenance. However, recent work has established that these structures are also a hindrance to DNA replication and failure to stabilise, repair or restart the replication fork is a potential source of genome instability, the hallmark of many diseases including cancer. Despite recent advances, the mechanisms that facilitate DNA replication at telomeres and other hard to replicate loci throughout the genome remain unclear. This proposal aims to address this important question in order to discover and decipher the mechanisms that help DNA replication through DNA secondary structures. I propose using multidisciplinary approaches to investigate the cellular response to replication stress at telomeres and the enzymatic activities that result in telomere replication aberrations, which will involve direct visualisation of telomere abnormalities using complementary DNA related methodologies and analysis of novel telomere-associated complexes. I also plan to determine the nature/structure of fragile telomeres, which remains poorly defined and represent a central question for the field using visualisation of biological molecules and proteomics. The detailed investigation of the function of known and new factors that facilitate telomere DNA replication represent an outstanding challenge that will provide a novel framework for understanding the contributions of replication factors in general DNA replication, genome stability and cancer in humans.

Keywords: telomeres,mammalian systems
Special Needs Lump Sum request to support hand-impaired ESR with sample preparation involving highly toxic hydrofluoric acidification (S2S-Future)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Action type: Marie Skłodowska-Curie actions
Countries involved: Switzerland
Call: MSCA Special Needs Allowance (H2020-IBA-MSCA-SNLS-2020, 2020)
Start date: 2021-09-01
End date: 2024-09-30
Duration (months): 37.0
Total project cost (EUR): 47325.0
EU funding (EUR): 47325.0
Participants: 1
Project status: SIGNED

Request of financial support to cover the additional costs that researchers/staff members with disabilities face due to the increased costs of their mobility and/or to ensure necessary assistance by third persons or for adapting their work environment.

Keywords: symbrachydactyly,hand impairment,hydrofluoric acid
DRY LAPping machine for water saving finishing processes in ceramic sector (DRYLAP)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Italy
Call: Boosting the potential of small businesses in the areas of climate action, environment, resource efficiency and raw materials (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-05-01
End date: 2016-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Water is used in almost all ceramic processes. The production cycle of porcelain stoneware in particular, as all wet production cycles, uses large quantities of water and generates considerable quantities of sludge. Currently, a line that processes 1.000.000 sq/m of tiles per year requires approximately 113.000.000 litres of water and generates sludge that contains more than 600 tons of abraded dust. It is estimated that the European ceramics industry, to produce approximately 1.300 million sqm of tiles, consumes more than 30.000 million cube meters of water, compared to the 8 million used by a city of approximately 300,000 inhabitants. In addition, the market demand in ceramic sector requires more and more products to have high intrinsic technical characteristics (reduced absorption, high surface hardness, abrasion resistance) that are typical of porcelain stoneware. These features are obtained through mechanical finishing treatment (polishing and lapping) of fired tiles. Unfortunately, there is a negative side to machining surfaces after firing: it implies the use of a considerable amount of water and generates and equally large amount of sludge. This generates waste, which in addition to material removed, also contains process water. The objective of the overall DRYLAP innovation project is to validate and launch on the market an innovative industrial process for the ceramic industries, that will allow to re virtually zero with respect to traditional production processes, the use of water. The DRYLAP project will focus on the finishing process of ceramic industry and it will aim at validating on the market a totally “dry” lapping machine that can be used to machine porcelain stoneware tiles compact paste ceramic products, that are the most commonly processed products in the European market.

Keywords: ceramic industries,low water use,ceramic process