Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A cost effective cloud-based platform for delivering the highest level of security, supervision and management for security companies utilizing Push-to-Talk and Internet of Things technologies. (QR-PATROL PRO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Greece
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-2-2015, 2015)
Start date: 2016-07-01
End date: 2018-12-31
Duration (months): 30.0
Total project cost (EUR): 1927422.5
EU funding (EUR): 1349195.75
Participants: 1
Project status: CLOSED

Terracom Informatics Ltd. was founded in 1999 and headquartered in northwestern Greece. Terracom has great experience in designing and developing software for security companies. In 2014 Terracom presented QR-Patrol, an innovative real time system for security guard tour patrol management. QR-Patrol is undergoing an impressive performance in the international market and within the first 18 months it acquires customers in 31 countries and business partners in 12 countries. The object of our proposal is QR-Patrol PRO. Based on commercially available QR-Patrol, it will be the first Guard Tour Patrol System which will integrate Internet-of-Things technologies in order to automate many of the routine procedures followed by security guards, provide accurate location data and monitor of worker's health and physical condition. It will also integrate a Push-To-Talk function providing secure group communication between the security guards and their company. It is a disruptive innovation system for the security industry and our goal is to become one of the dominant systems in the field of Guard Tour Management Systems. Beacons, Wearable devices and Push-to-Talk over IP are three technologies that will be integrated in QR-Patrol PRO will offer new, innovative, features for the security market. Our system will automate, simplify and accelerate the process of monitoring, supervising and communicating with security guards, saving significant business resources for the security company. As far as the competition concerned, there is a huge installed base of guard tour systems but actually they represent the past. They cannot offer real-time monitoring, flexible incident reports, photo-text-audio messages, two-way communication. Our target is worldwide aiming at the security and lone workers' market. We will establish the system through a network of partners. We are optimistic that we will handle the difficulties. This attitude originates from the faith in the success of our system.

Keywords: security guard tour patrol system mobile cloud application beacons wearable push to talk
Addressing Diversity: How Immigration Shapes Criminal Justice and Welfare Policies (DiverseJust)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-02-01
End date: 2022-04-30
Duration (months): 24.0
Total project cost (EUR): 212194.8
EU funding (EUR): 212194.8
Participants: 1
Project status: CLOSED

DiverseJust takes a novel approach to studying Denmark’s contentious policy debate on welfare and the criminal justice system in times of increased immigration and cultural diversity. Most current research focuses on either welfare or the criminal justice system, as theoretically separate entities. However, following Loic Wacquant’s work, this project examines policy changes in welfare and the criminal justice system, examining them as a compound of intimately connected policies that evolve in tandem in response to increased diversity in welfare states. I argue that to fully understand the evolution of welfare and criminal justice systems, we need to consider race and ethnicity as central variables that shape state response to deviance and poverty. Using expert interviews, the research project will explore (a) the impact that increased diversity has on the Danish welfare system, especially for immigrants; and (b) the impact that increased diversity has on the Danish criminal justice system. Ultimately, this study asks (c) how Denmark, a classic Scandinavian welfare state, may change in response to the challenges of increased cultural diversity.

Keywords: criminal justice,welfare,immigration,policy,expert interviews,neoliberalism,diversity
Synthesis and Biological Evaluation of Pyrroquinoline Pseudo-Natural Products (pyrroQuin)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: CLOSED

Natural products (NPs) and their structural scaffolds are a rich source of small molecule tools for chemical biology and drug candidates. In a novel approach, this proposal will investigate the combination of natural product fragments to form pseudo-natural products (pseudo-NPs) with uncharted biological activity. The purpose of this project is to explore the diastereo- and enantioselective synthesis of two pyrroquinoline scaffolds, a combination of pyrrolidine and tetrahydroquinoline fragments, and submit the obtained compound collections (>100 compounds) to phenotypical screening assays to assess their biological activity. The obtained molecules could potentially serve as novel biological probes and lay the foundation for the discovery of novel targets or drugs. Highly active compounds will be used to establish structure activity relationships (SAR) and design affinity isolation probes for the identification of cellular targets.

Keywords: evaluation of biological activity,stereoselective synthesis
Market introduction of a revolutionary innovative cardiac stimulation system for the prevention and termination of post-operative atrial fibrillation (DefiPace-System)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2019)
Start date: 2020-06-01
End date: 2023-11-30
Duration (months): 42.0
Total project cost (EUR): 2814215.0
EU funding (EUR): 1969950.5
Participants: 1
Project status: SIGNED

The incidence of cardiac surgeries is increasing world-wide in view of the demographic change. Cardiac surgery carries a significant amount of risk as on average 60% of patients develop postoperative atrial fibrillation, by far the most frequently occurring complication after cardiac surgery. Clinical investigations show a significant increase in morbidity, mortality and duration of treatment and hospital stay. The risk for stroke is increased 3-fold! From all discussions with renowned surgeons results the clear statement that an avoiding or reduction of medical drugs is in any circumstance a preferable and desirable ambition. The DefiPace™ system is a proven and awaited method by the physicians treating post-operative patients. Our new system is unique, as it is the only system in history and today, which allows physicians to prevent and terminate postoperative atrial fibrillation (POAF) in all patients. It is the only system which combines standard stimulation, bi-atrial pacing as well as epicardial low-energy cardioversion in one hand-held easy-to-use device even on general ward. Target customers are all patients undergoing cardiac surgery world-wide (market volume: € 1.5 billion). Advantages: Simplicity • TMA pacing & cardioversion wires: easy to use, similar to standard pacing wires • DefiPace device: Intuitive handling for clinical staff similar to standard external pacemakers Prevention and Termination: • Bi-atrial pacing as an effective way to prevent POAF • Quick Termination of atrial fibrillation with safe, elegant low energy cardioversion • No anesthesia necessary Cost savings for surgical clinics • Significant cost savings: at least €1,000per day/patient Improved health • Few or no medication required • All complications from atrial fibrillation can be completely avoided The DefiPace™-System is as a key product for OSYPKA and will lead to significant increase of sales and employees. We will revolutionize the pacemaker market a second time in our history

Keywords: heart operation,pacing,atrial fibrilation
Strategies Targeting Thyroid Hormone in Athrophy Related Syndromes (STARS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Italy
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-08-01
End date: 2021-07-31
Duration (months): 72.0
Total project cost (EUR): 1310000.0
EU funding (EUR): 1310000.0
Participants: 1
Project status: CLOSED

Skeletal muscle wasting is a devastating complication of many chronic diseases including cancer, diabetes, chronic heart failure and cystic fibrosis. Despite its medical importance, there is, as yet, no effective means to treat this condition. Therefore, an urgent challenge is to discover treatments able to prevent its onset and/or progression. Thyroid hormone (TH) is a major determinant of muscle functions, and thyroid dysfunctions are leading causes of many myopathies. An emerging concept in this field is that TH’s pleiotropic actions can be amplified or attenuated at cell level by the deiodinase enzymes that can increase (D2) or decrease (D3) the active TH concentration regardless of hormone plasma levels. Based on recent published and new preliminary data, our working hypothesis is that “amplification” of TH action/signalling in muscle is critical in determining the accelerated muscle catabolism that causes muscle loss in numerous diseases. On the contrary, attenuation of the TH signal facilitates the proliferation/survival of muscle stem cells and reduces atrophy. Using genetically manipulated mouse models of altered TH metabolism, STARS aims to dissect the role of TH in muscle fibers and stem cells during the wasting processes. The ground-breaking nature of STARS is the possibility of manipulating a local-acting mechanism that determines the tissue concentration of a diffuse endocrine signal (TH), which is a critical determinant of muscle wasting. We will use state-of-the art methodology and recently generated mouse models in the attempt to explore the therapeutic potential of novel mechanisms to lower the TH signature at a specific muscle level. Proof-of-principle studies will be conducted with novel hormone-peptide conjugates for targeted disease prevention and therapy. The results will have cross-disciplinary implications, for the identification of novel potential therapeutic approaches impacting on stem cell biology, tissue metabolism and healthy ageing.

Keywords: thyroid hormone,deiodinases,muscle atrophy
Novel Pesticides for a Sustainable Agriculture (NoPest)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Spain,Israel,Italy,Sweden,France,France
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2018)
Start date: 2019-01-01
End date: 2024-12-31
Duration (months): 72.0
Total project cost (EUR): 3236820.0
EU funding (EUR): 3236820.0
Participants: 8
Project status: SIGNED

Members of the oomycete phylum represent highly problematic crop pathogens and a threat for global food security. For instance, P. infestans is the agent of potato late blight, and P. viticola of grapevine downy mildew. Oomycete infections are currently controlled by frequent applications of copper-based compounds, but the massive use of these compounds leads to pollution, residual toxicity and adverse effects on human health. The discovery of innocuous and reliable alternatives to traditional inorganic fungicides remains challenging and has been set as a high priority by EU and other countries. NoPest aims to develop an environmentally friendly approach for crop protection as an alternative to conventional chemical pesticides. The strategy, inspired by medical and pharmaceutical research, relies on peptide aptamers to counteract oomycetes infections by i) identifying small peptides (linear/cyclic peptide aptamers) that inhibit vital enzymes involved in oomycete cell wall formation and cell stability; ii) optimizing aptamer efficiency through peptidomimetics designed for field applications; iii) searching, using chemo-informatics approaches, for non-peptide small molecules that mimic the activity of aptamers. These objectives will be addressed by selecting peptide aptamers from combinatorial libraries, based on their affinity and specificity for selected protein targets. Key benefits will be i) low probability to select resistant oomycete strains and no risk of co-selection of bacteria resistant to heavy metals; ii) no impact on animal and human health; iii) low environmental impact, as the approach is based on peptides that consist of natural amino-acids; iv) potential to develop additional products that confer antimicrobial resistance to any crop pathogen. Furthermore, in order to make the new molecules competitive in the pesticide market, precision farming non-invasive sensing tools will be developed, leading to reduced pesticide usage for field treatments.

Keywords: oomycete,anti microbial peptide,mimetic peptides
RAPID ACCELERATION OF CLIMATE ENTREPRENEURS (RACE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Innovative societies
Action type: Coordination and support actions
Countries involved: Netherlands
Call: Ensuring greater synergies by testing new collaboration mechanisms between the EIT Innovation Communities and the Enhanced EIC Pilot in support of the the Green Deal and other Union policy priorities - Climate (H2020-IBA-EIC-CLIMATE-2020, 2020)
Start date: 2021-07-01
End date: 2023-02-28
Duration (months): 20.0
Total project cost (EUR): 997921.25
EU funding (EUR): 997921.25
Participants: 1
Project status: SIGNED

The pilot project aims to develop and test coordination mechanisms between the EIC and EIT Climate-KIC and their innovation communities, looking specifically at synergies and complementarity between the two organisations. The project will test three areas with specific objectives aiming particularly at creating synergies to align and improve our innovation portfolios towards the European Green Deal goals. The first area of the proposal supporting EIC and 60 to 80 of its beneficiaries is focused on testing EIT Climate-KIC’s climate impact framework to forecast the climate impact of early-stage innovations and integrate a methodology for measuring systems transformation potential at a portfolio level, supporting a 1.5°C scenario. The second area suggests support up to 25 EIC beneficiaries stemming out of the EIC Pathfinder programming and especially under Transition to Innovation, Innovation Launchpad and/or the EIC Accelerator Early Stage Programme. It will identify and support those with ground-breaking climate innovations as well as those who are committed to bringing new products and/or businesses to the market and improve their market uptake. The third area of the project is looking to provide access to 10-15 EIT Climate-KIC’s later-stage portfolio companies to the EIC Accelerator, especially the newly created blended finance instrument. The goal of this work is to design an effective process to channel and fast-track EIT Climate-KIC qualified portfolio companies to EIC’s Accelerator instruments. The results of the project will lead to recommendations to frame a future long-term collaboration framework between EIC and EIT Climate-KIC under Horizon Europe.

Keywords: testing synergies,coordination,supporting innovators,climate impact,systems innovation
Participatory Engagement with Scientific and Technological Research through Performance (PERFORM)

Framework: Horizon 2020 — Science with and for Society
Programme: Make scientific and technological careers attractive to young students, and forster sustainable interaction between schools, research institutions, industry and civil society organisations
Action type: Research and Innovation actions
Countries involved: Austria,Spain,France,France,United Kingdom,United Kingdom,United Kingdom
Call: Innovative ways to make science education and scientific careers attractive to young people (H2020-SEAC-2014-1, 2014)
Start date: 2015-11-01
End date: 2018-10-31
Duration (months): 36.0
Total project cost (EUR): 1997252.5
EU funding (EUR): 1997252.5
Participants: 11
Project status: CLOSED

The PERFORM consortium aims to investigate the effects of the use of innovative science education methods based on performing arts in fostering young peoples’ motivations and engagement with science, technology, engineering, and mathematics (STEM) in selected secondary schools in France, Spain and the United Kingdom. A considerable percentage of young people in Europe is not interested in STEM careers mainly because they perceive that they lack the skills to deal with such topics. Such negative perceptions discourage adolescents from investing time in learning about science and undervalue the role of science in society. Addressing the challenge of engaging young people in STEM has never been more urgent in Europe in order to avoid loss of scientific talent and to ensure future innovation capability, excellence and competitiveness. PERFORM takes action to overcome the remaining distance between young people and science and to break the unidirectional model of scientific knowledge transfer. PERFORM will explore a creative, participatory educational process on STEM through the use of scenic arts with secondary school students, their teachers and early career researchers, who will get actively involved in experiencing science. They will also reflect on their own role in the interaction between science and society, and the values embedded in Responsible Research and Innovation. PERFORM will analyse how such human-centred, science-arts educational approach contributes to foster girls’ and boys’ motivations towards science learning and strengthen the transversal competences they will need for STEM careers and jobs. The education and communication skills required for teachers and researchers to further replicate the educational process will be explored and addressed in specific training toolkits. The project dissemination will be fulfilled by ensuring strong science-policy links and by linking PERFORM with Scientix.

Keywords: participatory action research,science and arts based education approach,secondary schools,young people s engagement
Advanced hoListic Adverse Drone Detection, Identification Neutralization (ALADDIN)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Fight crime, illegal trafficking and terrorism, including understanding and tackling terrorist ideas and beliefs
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Italy,Germany,Spain,Belgium,Greece,Greece,Poland,Poland,France,France,France,France,United Kingdom,United Kingdom,Portugal
Call: Technologies for prevention, investigation, and mitigation in the context of fight against crime and terrorism (H2020-SEC-2016-2017-1, 2016)
Start date: 2017-09-01
End date: 2020-12-31
Duration (months): 40.0
Total project cost (EUR): 4998240.0
EU funding (EUR): 4998240.0
Participants: 21
Project status: CLOSED

ALADDIN will study, design, develop, and evaluate, in series of complementary pilots, a counter UAV system as a complete solution to the growing UAV threat problem, building upon a state-of-the-art system and enhancing it by researching on various technologies and functionalities. ALADDIN will follow a holistic and heavily user-centred methodology involving a large number of LEAs and critical infrastructure operators, as well as an expert Advisory Board panel ensuring end-user diversity, as they all face different kinds of threats and work within different regulatory frameworks. This diversity is important to shape EU-wide system specifications and the innovative training curricula and training that will be realised to share the knowledge gained and raise awareness. Furthermore, within the project all regulations, social, ethical and legal elements will be studied thoroughly and continuously with an impact assessment produced and its results monitored during the project’s lifetime. ALADDIN’s sensing arsenal is comprised of a set of custom, innovative, and unique technologies as well as established and standard sensors used for UAV detection and localisation: 1) 2D/3D paired radars; 2) Innovative optro and thermal panoramic imaging; 3) Custom designed acoustic sensors. These will be fused through novel deep learning techniques in order to provide excellent detection accuracy. Further, ALADDIN will study and offer a set of neutralization effectors (jammers, physical and hacking). These sensing and countering capabilities will be operated through an advanced command and control (C2) system. The C2 will achieve great detection and classification accuracy within a large range, by fusing data acquired from all sensors through state-of-the-art deep learning techniques. Operator’s efficiency will be enhanced through a novel mixed reality interface with 3D cartographic and situational elements and will be complemented by support to operations like investigation and trainings

Keywords: multi modal fusion,deep learning,counter uav,mixed reality,advanced c2,3d cartography,computer vision,signal processing,radar,acoustic,jamming,hacking