Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Introducing the world’s first system for in-air haptic feedback, through ultrasound MEMs arrays (Haptictouch)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-04-01
End date: 2018-09-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

MyVox has developed a unique transducer-platform, based on a patented technology that combines microelectromechanical systems (MEMS) with the mimicking of the ultrasound senses used by bats. The ground-breaking innovation greatly reduces cost and makes it possible to combine actuators microsystems (haptic touch and audio feedback) with many different applications (mobile phones, tablets, cars, robots etc.). The disruptive nature of the technology lies in the design of the existing miniaturized MEMS platform, which enables in-air haptic & audio feedback function. MyVox solution actually eliminates the need for tools and touch-sensors and can therefore offer a wide variety of benefits. For example, in hospitals, where integrating MyVox haptic and audio-based sensor systems in equipment (thus removing the need for touching an actual surface and the use of a glove or other device), means that the contamination via common surfaces will be drastically reduced. Other examples of how disruptive MyVox ground breaking sensors are, is their integration in the cockpits of vehicles, where they will greatly reduce the risk of accidents by removing the need for taking the eyes of the road (with virtual buttons placed in the line of sight, rather than on the dashboard). As a visual aid (the sensor will allow a virtual button to have different surface feels, thus functioning as a virtual braille, etc.). Current pricing means that customers pay 1000 USD per unit (only one company offer something similar, although their solution is on a dm scale rather than MyVox sub-centimeter scale). MyVox aims to introduce its system at a cost below 50 USD, thereby reducing the cost by 95%. MyVox current business plan indicate a possible revenue of 1.5 Million Euro in 2020, 8 Million Euro in 2021 and 30 Million Euro already in 2022 for the sensor platform alone. Adding haptic and audio feedback means the market share will grow exponentially as there are no competing solution world wide.

Keywords: haptic feedback,virtual objects,3d imaging
Guns for a Global Empire: Deployment of Artillery Technology in the Iberian Colonial Space (1580-1640) (GLOBALGUNS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2022-12-21
Duration (months): 36.0
Total project cost (EUR): 259398.72
EU funding (EUR): 259398.72
Participants: 1
Project status: CLOSED

This project studies the historical relationship between military technology, globalization and the rise of European overseas empires by focusing on the provisioning system of cannons in the first political entity which ever connected the four parts of the world: the Iberian Union (1580-1640). If cannons have become a symbol of early modern European expansion, no study has tackled their contribution in sustaining overseas conquests. In defence of dozens of sea-fortresses and on board of hundreds of ships spread around the globe, cannons played a crucial role in the first globalization as key infrastructures of the Iberian empires. The project aims to shed light on this world-wide deployment of artillery technology by revealing the emergence of a system combining gun-manufactures in Europe, America and Asia, all connected through circulations of weapons, raw material and technical experts. The special attention granted to the actors of the system intends to highlight the importance of human capital in the imperial state-building and globalizing processes. The project implements a twofold interdisciplinary methodology: while computer software is used in order to quantify and map the system, archival sources are crossed with material evidence coming from the wide collections of cannons hold in museums so as to reveal circulations and hybridizations of knowledge. Complemented by thorough archival work on case studies about the gun-foundries in Mexico, Cuba, Manila and Macau, this research addresses the issue of technological asymmetries between centres and peripheries inside the Iberian empires and questions the role of European colonial spaces in the globalization of the military revolution. By doing so, this project contributes to two EU priorities as it provides a reflection, from a historical perspective, on Europe’s place in a global context and generates knowledge on the cultural heritage of European coastal areas regarding their proto-industrial developments.

Keywords: military revolution,spanish empire,portuguese empire,history of technology,cannon manufactures,circulation of knowledge,digital humanities,material culture,global history,early modern history
Artificial Intelligence SaaS for prescribing optimal retail merchandising decisions (Formulate)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

During the fall of 2018, retail sales broke new records throughout Black Friday, Cyber Monday and Single’s day. This should be good news for retailers, but the reality is that there’s a dark side to these triumphs - a large part of growth is driven by an increase of promotions, which is eroding the margins of many retailers. In fact, our data suggests that more than 70% of all supplier promotions and well above 30% of all retail promotions are unprofitable, even after adjusting for supplier funding. Particularly this hits the SMEs that feel much pressure from large players such as Amazon or Alibaba but do not have necessary competence and capacity to survive the competition. Formulate aims to provide a solution to these challenges by offering its DecisionCloud, a platform that combines our AI with company’s transaction data to create better stores and more satisfied customers. Whether it comes to selecting promotion items, the optimal price tactic, right media, or campaign timing, we empower the right decision for any retailer’s business. Based on our findings and our collaboration with academia, Formulate can double the impact from the merchandising decisions. With its full automation of AI, distributed analytics capabilities, low IT cost and easy on-boarding, Formulate stands out of competition. But most importantly, the product creates a much-needed market change and generates great positive impact on the retailer-supplier dynamics. Our ultimate goal is to enable retailers of all sizes – not only the largest tech giants – to have access to advanced AI that automates merchandising decisions. The key objective of our project is to transform an initial business plan into a robust strategy for international commercialization and to prepare for a Phase 2 development. With this objective in mind, our Phase 1 project will consist of a more precise market evaluation, assessing technological needs for further scaling and optimizing our go-to-market strategy

Keywords: retail,merchandising,promotions,automation,saas,analytics
Bordering Europe: Boundary Formation and European Integration (EUROBORD)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Switzerland
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2021-11-01
End date: 2026-10-31
Duration (months): 60.0
Total project cost (EUR): 2477206.0
EU funding (EUR): 2477206.0
Participants: 1
Project status: SIGNED

Integration crises and geopolitical shifts have put the borders of the European Union (EU) in the focus of attention and contestation. Current developments highlight how strongly European integration is affected by outside events and cross-border transactions. Yet theories of European integration focus almost exclusively on the internal boundaries between the member states. EUROBORD therefore develops and tests a novel ‘bordering theory’ aiming to explain how external boundary developments affect the trajectory of integration. The bordering theory proposes an account of how ‘bordering’ – the making and configuration of the EU’s boundaries – affects ‘ordering’: the structure of politics and institutions in the EU. Specifically, it analyses how ‘debordering’ (the expansion, opening and incongruence of the EU’s boundaries) in the post-Cold War period has generated integration problems and political conflicts, which have triggered a process of ‘rebordering’ (retrenchment or closure) in turn. EUROBORD examines the conditions and mechanisms that lead to alternative configurations of the EU’s boundaries. EUROBORD introduces innovative conceptual frameworks, automated data collection techniques and new datasets to map the changing configuration of EU borders and study their effects on (i) economic, cultural, political and military transactions across these boundaries, (ii) member state political performance, (iii) European party positions and conflict, and (iv) boundary policies and the trajectory of European integration. This comprehensive data allows EUROBORD to conduct the first systematic empirical study of the effects of external bordering in European integration, using a mix of panel analyses and case studies. EUROBORD will thereby generate a more complete and adequate understanding of the dynamics of European integration and provide insights on the political causes and effects of border design.

Keywords: european integration,european union,borders,institutions
PJ34-W3 AURA “ATM U-SPACE INTERFACE” (PJ34-W3 AURA)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Spain,Austria,Germany,Germany,Germany,Ireland,Italy,Italy,Germany,Belgium,Croatia,Hungary,Lithuania,Romania,Slovakia,Sweden,Sweden,Norway,Belgium,Poland,France,France,France,France,Czechia,Czechia,Netherlands,Denmark,United Kingdom,Denmark
Call: Collaborative U-space-ATM interface (H2020-SESAR-2020-2, 2020)
Start date: 2021-01-01
End date: 2023-06-30
Duration (months): 30.0
Total project cost (EUR): 11666050.53
EU funding (EUR): 7978319.51
Participants: 47
Project status: SIGNED

The global objective of AURA is to lay the foundations for the integration of the new entrants in current and future air traffic environment, developing the required concept of operations and validating U-space services information exchanges with ATM systems. In order to achieve this objective, all relevant stakeholders (drone operators, U-space service providers, data services providers, ATM providers and authorities) will be included during the project development and throughout its lifetime. AURA project will identify the requirements for U-space information exchange with ATM through SWIM and will validate a set of selected U-space services, developing the service definition for the SWIM candidate services. Secondly, it will define a novel Collaborative ATM-U-space Concept of Operations (ConOps) for drones in a fully collaborative environment with ATM that go beyond the existing concepts developed for a U-space and will validate these new concepts. AURA project will contribute to enable the development of Very Low Level (VLL) markets, allowing the introduction of new actors in a safe, harmonized, sustainable and efficient way and compatible with current ATM environment. Also, the project will contribute to avoid the segregation of the airspace and increase the interoperability. AURA will provide inputs for the current regulatory and standardization initiatives regarding U-space with a high involvement of external stakeholders through an Advisory Board.

Keywords: u space,swim,collaborative interface
Adapting and maintaining the innovation management assessment tools and support Enhancing the innovation management capacity of SMEs (IMP3rove for Future)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Germany
Call: INNOSUP (H2020-Adhoc-2014-20, 2014)
Start date: 2014-10-01
End date: 2019-06-30
Duration (months): 57.0
Total project cost (EUR): 2330022.0
EU funding (EUR): 2330022.0
Participants: 1
Project status: CLOSED

IMP³rove for Future will build on the proven and well-tested innovation management support services developed in the previous IMP³rove projects initiated by the European Commission to help mainly the Enterprise Europe Network (EEN) using IMP³rove services for "enhancing the innovation management capacity of SMEs". Furthermore, IMP³rove support services and training programs will be developed to address up-coming needs of SMEs and the support providers. In seven work packages an operational and capacity building / training environment will be created: Innovation management training programs will be further developed and implemented for EEN and other innovation support providers. Coaching of EEN partners in rendering effective innovation management assessments based on the IMP³rove benchmarking tools, and new benchmarking features will be developed. Actions in regions and Member States to develop better programs to enhance innovation management capacity at SMEs will be supported with new IMP³rove products and services. Within this project also the European and international standardisation activities in innovation management will be supported. The project will actively involve the key stakeholders in shaping the training program, the new features of the IMP³rove platform and in delivering the IMP³rove support services in the most effective manner. The expected results of this 28 months project are more than 400 EEN members rendering effective innovation management benchmarking services and support to SMEs, more than 4,000 SMEs that have benefited from the IMP³rove services and have been put on the growth track and about 10 other actors in regions and Member States developed better programs for innovation management capacity building of SMEs. They all can rely on the IMP³rove methodology and assessment tools and services compliant with international standards in innovation management.

Keywords: innovation management,innovation management capacity building,innovation support programs,innovation management benchmarking,innovation management training,standardisation
A tissue-on-a-chip platform for systems-level studies of ALS pathology and drug screening (Als-on-a-chip)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Greece
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-30
End date: 2017-09-29
Duration (months): 24.0
Total project cost (EUR): 164653.2
EU funding (EUR): 164653.2
Participants: 1
Project status: CLOSED

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease, which affects approximately 2 per 100000 people. Currently, there is no ALS treatment. The main tool for preclinical ALS studies is the hSOD1G93A mouse. However, despite promising results in this model, all candidate drugs failed in clinical trials. These failures have been partly attributed to differences in the physiology of human and mice nerve cells, and the inability of the established drug design approach to block ALS pathology. There is urgent need for new tools that will complement this mouse model, improve understanding of ALS pathology, and suggest better leads for clinical trials. The objective of the proposed study is to develop a tissue-on-a-chip platform for systems-level studies of ALS pathology and drug screening. The system is built around a novel thin porous scaffold, where systems of normal or ALS-type mouse and human motor neurons will be cultured inside an appropriate 3D ECM analog, and their response (intracellular signaling, cell processes, cell-cell communication) to stimuli panels in the presence of drugs will be quantified via high-throughput proteomics and fluorescent imaging. Acquired data will be interpreted by modifications of state-of-the-art system biology tools. The outcomes of the proposed research can lead to new ALS treatments by identifying new drug targets (via mechanistic description of ALS pathology), and by developing better ways to evaluate candidate drugs before clinical trials (via comparing drug response in human and mouse cells). Results can be translated to other neurodegenerative diseases. Finally, the proposal offers an opportunity to a promising researcher to relocate from MIT to Greece, collaborate with a leading neurobiology lab in a world-class environment and a systems pharmacology SME, and translate his research via two startup companies. The host envisions the opportunity for a tenure-track faculty position for the experienced researcher.

Keywords: neurodegeneration,organs on a chip,systems pharmacology,systems biology
Regulation of DNA interstrand crosslink repair by ubiquitin. (ICLUb)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: United Kingdom,United Kingdom
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-09-01
End date: 2022-08-31
Duration (months): 72.0
Total project cost (EUR): 1999998.0
EU funding (EUR): 1771592.59
Participants: 2
Project status: CLOSED

The overall objective of this proposal is to understand, on an atomic level, the mechanism of activation and regulation of the Fanconi Anemia (FA) DNA repair pathway. Homozygous mutations in the FA pathway lead to Fanconi Anemia, a devastating childhood genome instability disorder, typified by bone marrow failure and a high predisposition to cancers. The FA pathway is required for the repair of DNA interstrand crosslinks (ICLs), the hallmark of many cancers and FA. ICL repair is poorly understood on a biophysical and mechanistic level. The FA pathway is regulated by ubiquitin, in a cycle of monoubiquitination and deubiquitination of FANCD2. Despite considerable advances in our understanding of the genetics of the pathway, there is strikingly little known on a mechanistic and chemical level concerning how the ubiquitin signal is assembled, recognised and disassembled. We will define, on an atomic level, the site-specific monoubiquitination and deubiquitination cycle of FANCD2 in its entirety. We will determine the mechanism of FANCD2 monoubiquitination, identify and characterise currently unknown readers of the monoubiquitin signal, define the role of the core complex in the modification of FANCD2, and the requirements for removal of the signal. To tackle this ambitious work we will determine the atomic level three-dimensional structure of key complexes in the modification cycle, and develop a novel method for producing large quantities of stably modified FANCD2. The results of our work will represent a major breakthrough in our knowledge and understanding of the regulation of a critical DNA repair process, will provide a model for understanding mechanisms of monoubiquitination, and will open up both therapeutic potential and new pathways for research into the cause and cure of FA, cancers, and aldehyde-induced liver or bone marrow failure.

Keywords: ubiquitin,posttranslational modification,fanconi anemia
GloPID-R Secretariat (GloPID-R SEC 2)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Coordination and support actions
Countries involved: France,United Kingdom
Call: Support for the functioning of the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R) (H2020-SC1-2019-Single-Stage-RTD, 2019)
Start date: 2020-01-01
End date: 2022-12-31
Duration (months): 36.0
Total project cost (EUR): 2211538.93
EU funding (EUR): 2152623.48
Participants: 2
Project status: CLOSED

GloPID-R-Sec II is the secretariat to the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R). The partners FMER and UOXF have been successfully running the GloPID-R Secretariat (hereafter” the Secretariat) for the last five years (2015-2019). The current GloPID-R Secretariat-staff involved at FMER and UOXF will also be involved in GloPID-R Sec II, guaranteeing a smooth transition and continuity from the current Secretariat to its new funding period. The activities of the Secretariat encompass: - Organisational-secretarial support for smooth and efficient implementation of the operational activities of GloPID-R (e.g. organisation of meetings, maintenance of the GloPID-R Charter, financial monitoring and reporting) - Implementing, evaluating and maintaining an effective external communications programme to build the GloPID-R membership and support for GloPID-R; - Providing ‘on demand’ technical support for the further development and operationalisation of GloPID-R’s strategy. This includes amongst others, (i) Operational support to facilitate rapid and aligned funding of research in outbreak emergencies, (ii) Technical support to research preparedness to reinforce rapid response capacities and (iii) Coordination activities to reinforce GloPID-R’s visibility and capacity to operate as a global platform.

Keywords: organisational support,secretarial support,technical support