Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Matteco PGM-free Cathodes for Next Generation Hydrogen Production (MATCATH2.0)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain
Call: Transition Open 2024 (HORIZON-EIC-2024-TRANSITION-01, 2024)
Start date: 2025-05-01
End date: 2028-04-30
Duration (months): 36.0
Total project cost (EUR): 3450281.26
EU funding (EUR): 2415196.88
Participants: 1
Project status: SIGNED

The European Union's ambitious 2030 target for renewable hydrogen production is impeded by the cost-efficiency of current electrolysis technologies. The prevalent use of bare nickel substrates or those coated with costly platinum-group metals (PGMs) and critical raw materials (CRMs) in cathodes often leads to contamination and instability, resulting in substantial efficiency losses. These issues, exacerbated by the high costs and complexities of traditional catalyst coating methods, highlight the critical need for innovative solutions to advance electrolysis technology and achieve the EU's hydrogen production targets. Matteco is at the vanguard of revolutionizing hydrogen production with the development of PGM-free cathodes that utilize advanced, earth-abundant catalyst materials and a proprietary substrate coating method. This innovation is set to achieve a significant 75% reduction in cathode costs and a 20% decrease in the Levelized Cost of Hydrogen (LCOH), aligning with the EU's goals for decarbonization, CRM reduction, and circular economy promotion. Matteco's cathodes are engineered to outperform existing PGM-based alternatives, ensuring sustainable production, longer component life, and recyclability at end-of-life. The MATCATH2.0 project represents Matteco's strategic commitment to advance our novel thermal reductive catalyst activation process for cathodes at a commercial scale. Through stringent quality control and extensive internal and external testing with potential customers, Matteco will validate the cathodes' exceptional performance and stability. Advancing from TRL 4 to TRL 6, MATCATH2.0 will ensure a scalable and cost-effective production method, drawing on product validation and customer feedback. With a 36-month timeline and a 2,49 M€ investment, MATCATH2.0 is poised to propel the hydrogen economy towards a more sustainable and economically viable future.

Keywords: electrolysis,water electrolysis,hydrogen production,cathode,electrodes,pgm free,proprietary coating process
Developing broad-spectrum antiviral drugs for pandemic preparedness (PANVIPREP)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: Netherlands,France,Switzerland,Hungary,Belgium,Germany,Czechia,Spain
Call: Pandemic preparedness and response: Broad spectrum anti-viral therapeutics for infectious diseases with epidemic potential (HORIZON-HLTH-2023-DISEASE-03, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 7999298.25
EU funding (EUR): 7999295.0
Participants: 17
Project status: SIGNED

Antiviral drugs will be key in the management of future virus outbreaks. For each virus family with epidemic/pandemic potential, stockpiles of potent drugs are needed that can be deployed when a new pathogen emerges. Such broader-acting drugs (targeting conserved viral functions) are needed as of “day one” of an outbreak, for treatment and prophylaxis (e.g., in HCW and frail patients). In combination with quarantine measures, such drugs will delay (global) spread, allowing time for vaccine-development. Since the 2003 SARS outbreak, PANVIPREP’s core partners have successfully collaborated in leading European antiviral drug research projects. This provides a solid scientific basis in combination with translational drug discovery expertise. The team includes virologists, biochemists, structural biologists, medicinal chemists and pharmacokinetics experts. Previously developed know-how and toolboxes will be a major asset to achieve immediate impact. PANVIPREP aims to greatly expand the antiviral portfolio and identify novel druggable targets of high-risk RNA viruses. Hits will be identified through (i) phenotypic antiviral screening of compound libraries (ii) structure-based drug design, (iii) in silico screening, supported by the latest machine-learning methods. We will deliver 25 to 50 high-quality, broad(er)-spectrum (pan-genus/pan-family) hit molecules/hit series. Two of these will be developed to the early lead stage, including proof of concept in animal infection models. Remaining hits will serve as chemical tool-compounds to explore mechanisms of action thereby identifying novel druggable targets in RNA virus replication. This in turn will accelerate target-based drug design efforts. The workflow will integrate best practices in antiviral drug discovery with a range of methodological innovations, including AI-based methods, thus renovating and accelerating the antiviral hit discovery pipeline future use and contributing to pandemic preparedness.

Keywords: high risk rna viruses,antiviral drug development,hit to lead development,medicinal chemistry,drug development pipeline,viral drug targets
Cellular models for tissue function in development and ageing (Cells2Tissues)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Integrative B iology : from Genes and Genomes to S ystems
Panel description: For all organis ms: Genetics, epigenetics, genomics  and other ‘omics studies , bioinformatics, systems biology , genetic diseases , gene editing, innovative methods and modelling,  ‘omics for personalised  medicine
Countries involved: Israel
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 2937179.0
EU funding (EUR): 2937179.0
Participants: 1
Project status: SIGNED

One of the most fundamental challenges in contemporary biology is in fact also one of the most classical ones: how to comprehend macroscopic tissue function from the activities of its microscopic cellular components. The remarkable advent of single cell genomics over the last decade is realizing this challenge at unprecedented scales. Measurements of the molecular states of thousands or even millions of cells can now be acquired efficiently, and tools for describing cellular states phenomenologically became well established. But how to model ensemble of cells in tissues is paradoxically even more difficult than before given this new unprecedented experimental resolution. To this end we will develop a new computational and theoretical framework for understanding ensembles of single cells as they interact and dynamically differentiate, proliferate or degrade. Parametric and mechanistic models for defining microscopic cell states over a mathematical manifold will be developed, and the dynamics of ensembles of cells over time and in space will be inferred from new experimental approaches capturing whole tissues over time or within spatially registered domains. Importantly, our models will describe tissues dynamics as change in specific gene regulatory, epigenomic and signaling programs, and we will develop high throughput experiments to combinatorically perturb embryonic and hematopoietic systems in order to test such models extensively. Our research will thereby extend single cell-centric models toward describing dynamics in tissues, with experiments and data collection aiming at rapid translation of the models to actionable and testable strategies for manipulating systems of interest. This will be applied to transparent and epigenetically precise cell type engineering, to discoveries using a unique resource on human hematopoietic ageing and to deep tissue level analysis of combination immunotherapy.

Keywords: single cell genomics,transcriptional manifolds,epigenetics of embryonic development,blood ageing
Translating Islam. The European understanding of Islam and the influence of dragoman translations on the inter-religious dialogue between Christians and Muslims (1730-1750). (TransIslam)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-01
End date: 2027-01-31
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 3
Project status: SIGNED

The project aims to bring to light the only planned venture financed by a European country to explore Ottoman culture before the development of 19th century orientalism and colonialism. Through the analysis of the French translation of a high-value group of 10 religious-themed Ottoman manuscripts, I aim to contribute to the combat of today’s Islamophobic societal sentiments - still largely conditioned by outdated Christian stereotypes and generally unaware of peaceful Christian-Muslim relations documented in recent scientific studies - by encouraging widespread societal re-education initiatives designed to improve an objective and unprejudiced understanding of Islam. The body of texts, selected from a collection of around 120 translations on various topics (still completely unknown to the scientific community) commissioned in 1730-1750 by the French government to dragomans (the official interpreters of the embassy in Istanbul) and “jeunes de langues” (dragoman apprentices), and conserved at the Parisian Bibliothèque nationale de France (BnF) since the first half of the 18th century, will be the principal field of inquiry to examine whether, to what extent, and in what way dragoman translations contributed to the spread of such European perceptions of Islam, and eventually impacted the inter-religious relations between Christians and Muslims.

Keywords: inter religious dialogue,mis understanding of others,islamophobia,translation cross cultural transfer,oriental studies,linguistic and intercultural mediation,history of the book and reading
Forecasting and Preventing Human Errors (FORHUE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer Science and Informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 1999629.0
EU funding (EUR): 1999629.0
Participants: 1
Project status: SIGNED

Human errors remain the main source of incidents. They can lead to fatalities, traffic accidents, or product defects and cause high economic and social cost. While some errors can still be corrected if they are detected in time, many human errors cause high costs as soon as they occur or are even irreversible. In these cases, it is very important to recognize human errors before they occur. The goal of this project is therefore to develop methods based on artificial intelligence that forecast human errors from video data. We focus on erroneous and unintentional human actions and we aim to support humans to avoid them. In order to achieve this goal, we aim to solve three tasks jointly. We aim to develop methods that forecast human motion and intention with a very low latency such that unintentional actions can be recognized before they occur. Without the capability to interfere, however, even the best forecasting model does not prevent human errors. We therefore aim to develop a model that generates an auditory feedback if an error is forecast. The feedback, however, should not only warn humans, but also guide them such that they can successfully complete their intended action. Finally, we aim to model how humans will react to the feedback. We thus aim to develop a model that forecasts the motion of humans and objects they interact with, that recognizes human errors before they occur, and that guides the human motion via auditory feedback in order to prevent errors. The model should automatically decide if and what auditory feedback is generated by reasoning how the feedback will affect the motion of persons that are close-by. While we aim to showcase that the developed technology is able to prevent errors before they occur, this technology has the potential to drastically reduce the social and economic costs caused by human errors in the long term.

Keywords: forecasting activities,forecasting human motion,video understanding,recognizing unintentional activities,forecasting human errors
Development of a multimodal toolbox to ensure a fast and reliable diagnosis of consciousness disorders (DOC-BOX)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium,France,Spain,Poland,Austria,Italy,Germany,Netherlands,United Kingdom
Call: MSCA Staff Exchanges 2022 (HORIZON-MSCA-2022-SE-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 1219657.14
EU funding (EUR): 1099400.0
Participants: 17
Project status: SIGNED

DoCBox aims to develop a new toolbox of fast and easy-to-implement behavioural, neuroimaging and neurophysiological assessments to accurately assess and diagnose patients suffering from a disorder of consciousness (DoC), allowing for a more comprehensive examination and better management of this vulnerable population. This toolbox will respond to the society needs regarding the evaluation of patients with DoC as it appropriately responds to the rigid time constraints of clinical settings, which are one of the biggest limitations for an accurate diagnosis. This project aims to enhance interdisciplinary research on DoC via an exchange of knowledge and international scientific cooperation to translate and validate the tools (e.g., behavioral scales, pipelines) that will be included in this toolbox. This collaboration between the partners underpins the credibility and feasibility of three research objectives: 1) Provide new bedside assessment tools to refine and optimize the detection of consciousness signs in post-comatose patients; 2) Identify the most accurate neurophysiological and neuroimaging biomarkers of consciousness states and develop novel easy-to-use software to implement these analyses in clinical settings; 3) Engage informal and formal caregivers in the diagnosis of DoC patients. This will ultimately result in guidelines and policy recommendations for improvement of DoC patients’ diagnosis and thus care. The proposed exchange program aims to bring together a large international and interdisciplinary consortium of 17 partners (EU and non-EU countries) including researchers and other professionals with all necessary skills, permitting to tackle the challenges faced by professionals when studying and caring for DoC patients. The benefits for Europe are the intersector and interdisciplinary massive data collected by this consortium, which will allow a major progress in the understanding of (disorders of) consciousness.

Keywords: disorder of consciousness,diagnosis,assessment,scale,care guidelines,neuroimaging
Scalable and Quantum Resilient Heterogeneous Edge Computing enabling Trustworthy AI (SMARTY)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: Italy,Germany,Hungary,Denmark,Israel,Poland,Spain,Netherlands,Romania
Call: Focus topic on Integration of trustworthy Edge AI technologies in complex heterogeneous components and systems (IA) (HORIZON-KDT-JU-2023-1-IA, 2023)
Start date: 2024-06-01
End date: 2027-05-31
Duration (months): 36.0
Total project cost (EUR): 31999656.45
EU funding (EUR): 9692779.02
Participants: 34
Project status: SIGNED

SMARTY invokes a cloud-edge continuum, made from heterogeneous systems, that protects data-in-transit and data-in-process in order to offer a trustful fabric to run AI processes. The securitization occurs by employing novel accelerators for quantum resilient communications, confidential computing, software defined perimeters and swarm formation, offering multiple layers of security. Semantic programmability and graph-management open the door to drag-and-drop approaches in deploying services in a fast and reliable manner. SMARTY is proposed within the context of different key sectors in Europe : automotive, fintech, telco and industrial settings; the technology proposed in SMARTY will be matured within the lifetime of the project and tested through five use cases. SMARTY is supported by large European industry players and well as by 13 SMEs which will seek a visible platform to develop their products and gain visibility towards high-growth. SMARTY’s major suppliers and OEMs and reputable academic partners provide a great opportunity for these 13 SMEs to mature their technologies in a challenging but safe environment. The results of SMARTY are applicable to different vertical sectors and can be transported to different use cases. Strong synergies with existing efforts in the area of edge computing, European processors and trustworthy AI are envisioned and planned within SMARTY.

Keywords: edge computing,postquantum cryptography,confidential computing,software defined perimeters,graph knowledge,semantic programming,artificial intelligence
Federated Learning-based Distributed Control for Heterogeneous Platoons of Connected Autonomous Electric Vehicles (FEASIBLE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-15
End date: 2026-09-14
Duration (months): 24.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 1
Project status: SIGNED

To promote the EU's sustainable development of environment and economy, EU planned to reduce emissions from conventional vehicles in European Green Deal. Heterogeneous platoons of connected autonomous electric vehicles (HPCAEVs) are thought to be the most efficient, viable, and promising solution to reduce both energy consumption and pollutant emissions produced by conventional vehicles and improve road efficiency. However, since HPCAEVs are still in the evolving stage, the secure and energy-saving operation of HPCAEVs in mixed traffic flow is suffering significant challenges. The FEASIBLE project is proposed in the context of addressing these challenges by providing some scientific foundations that enable the secure and energy-saving operation of HPCAEVs in mixed traffic flow, with particular focus on networked modeling, stability analysis, and control design. First, network-level federated learning (FL) models will be set up by incorporating intrinsic characteristics of HPCAEVs, macroscopic traffic flow, surrounding vehicle flow, and their interactions. Second, novel stability analysis criteria for HPCAEVs will be derived with expected dynamic performance by designing a FL-based Lyapunov function with sufficiently small and bounded modeling error. Third, FL-based distributed robust model predictive control methods for HPCAEVs with intervehicle distance constraints will be developed under surrounding road conditions. Finally, advanced simulations and tests of HPCAEVs will be conducted to demonstrate the effectiveness and practicality of the proposed modeling and control methods, and the control performance will be compared with cutting-edge methods.

Keywords: autonomous vehicle platoons distributed control secure operation emission reduction energy conservation
Modular and Scalable Architecture for Affordable SatCom User Terminals (ConnecTile)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Belgium
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Global satellite connectivity infrastructure is undergoing massive expansion, with LEO constellations projected to grow from 10,000 to 70,000 satellites by 2030, enabling critical applications from remote monitoring to rural broadband. TUSK IC disrupts the market with a critical enabling technology achieving 10x improvement in cost-performance: the first standard CMOS implementation of Ka-band functionality previously requiring expensive specialty semiconductors. Our ConnecTile modular antenna-in-package architecture integrates beamformers, low-noise amplifiers, and antenna arrays into pre-tested modules. ConnecTile modules can be tiled seamlessly and scaled for any application from portable user terminals to massive ground stations enabling unique use cases. Our solution reduces integrated circuit costs, which represent up to 50% of terminal BOM. We enable European ground terminal manufacturers to compete on both price and performance with overseas monopolies that currently control over 80% of the market. Our solution delivers superior beam tracking, reduced interference, more user cells, higher throughput at lower cost, thereby we directly support Europe’s strategic autonomy in satellite communications. With technology validated through ESA programs and early industrial traction, our company is positioned to supply the core IC platform for Europe’s next-generation Ka-band terminals, powering the transition toward a competitive, sovereign satellite communications ecosystem while capturing significant market share.

Keywords: ka band cmos beamformer,millimetre wave,flat panel antenna,leo satellite ground terminals,iris2 constellation,eu chips act,satellite operators,satcom sovereignty