Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Simulations for multi-level Analysis of interactions in Tunnelling based on the Building Information Modelling technology (SATBIM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-05-01
End date: 2018-11-30
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

With increasing urbanization and mobility, the need for underground facilities and consequently efficient and safe design and construction techniques grows. The goal of the SATBIM project is to develop a multi-level simulation model for tunnel-structure interaction integrated in the framework of Building Information Modelling to support engineering decisions during the project life cycle and to allow for the evaluation and minimization of risks on the existing infrastructure. SATBIM is an integrated platform for structural analysis, visualisation and optimization of the mechanized tunnelling process from early stages of the design over to the construction and the operation phase. The complete concept will be validated using industrial data with reference to the Rastatter tunnel project in Germany. The output will have wide implication on technology with expected high academic and industrial impact.

Keywords: mechanised tunnelling,building information modelling,numerical analysis,metamodelling,visualisation
Multi-Stakeholder Platform for a Secure Supply of Refractory Metals in Europe (MSP-REFRAM)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Enabling the transition towards a green economy and society through eco-innovation
Action type: Coordination and support actions
Countries involved: Germany,Spain,Spain,Spain,Spain,Belgium,Finland,Greece,Sweden,Finland,Poland,Sweden,France,France,France,France,France,Netherlands
Call: Raw materials partnerships (H2020-WASTE-2015-one-stage, 2015)
Start date: 2015-12-01
End date: 2017-06-30
Duration (months): 19.0
Total project cost (EUR): 1499760.0
EU funding (EUR): 1499760.0
Participants: 22
Project status: CLOSED

Refractory metals (tungsten, tantalum, rhenium, molybdenum and niobium) are highly strategic metals today mainly imported from a few countries. The European primary production remains below a few percentage. However, resources exist in Europe, as primary resources but mainly as secondary resources (industrial waste, urban mines). Valorizing these resources requires coordination and networking between researchers, entrepreneurs and public authorities to harmonise technologies, processes and services, develop standards, create new potential for export of eco-innovative solutions and for seizing new markets MSP-REFRAM will address these challenges by creating of a common multi-stakeholder platform that will draw the current refractory metals value chains and identify its innovation potential in order to support the implementation of the EIP on Raw Materials. Coming from industry, research, public sectors and civil society, both Consortium Members and External Experts have joined forces with expertise covering the whole value chain including mining, processing, recycling, application. The outputs of MSP-REFRAM will help Europe improve the supply value chain of refractory metals in the coming years, optimising the use of external resources as energy and water and at the same time reducing the amount and the toxicity of waste. MSP-REFRAM will share its conclusions widely and efficiently, in a long lasting way thanks to the support of the PROMETIA association. To ensure the systemic change, the outcomes of the project will be made available to the stakeholders and to the public through different tools and reports. In the medium term, MSP-REFRAM will contribute to better-informed decision-making at EU and national level as well as industry by proposing innovative value chains that will boost the refractory metals sector. In the longer term, this should improve the availability of these refractory metals, while creating greater added value to the economy and more jobs.

Keywords: refractory metals resources industrial waste supply value chain mining
qualification of High pErformance pRogrammable Microprocessor and dEvelopment of Software ecosystem (HERMES)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling European competitiveness, non-dependence and innovation of the European space sector
Action type: Research and Innovation actions
Countries involved: Italy,Spain,France,France,France
Call: Technologies for European non-dependence and competitiveness (H2020-SPACE-2020, 2020)
Start date: 2021-03-01
End date: 2024-02-29
Duration (months): 36.0
Total project cost (EUR): 3059001.25
EU funding (EUR): 3056751.25
Participants: 6
Project status: SIGNED

The HERMES project sets clear and measurable main objectives to reach a TRL 6 from TRL 4 as follows: 1. Development and testing of very complex ceramic hermetic package CGA 1752 – TRL 6 achieved 2. Space ESCC evaluation of the rad-hard FPGA (NG-ULTRA) developed under ESA, CNES and EU projects – TRL 6 achieved 3. Development and validation by end-users of several software tools including BAMBU HLS, Xtratum hypervisor and BL1 – TRL 6 achieved

Keywords: fpga,programmable
A pooled CRISPRi screen to identify new cell cycle proteins in the opportunistic human pathogen Streptococcus pneumoniae (GetToKnowPneumo)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-04-01
End date: 2021-03-31
Duration (months): 24.0
Total project cost (EUR): 191149.44
EU funding (EUR): 191149.44
Participants: 1
Project status: CLOSED

There is much truth in the ancient Chinese saying; “if you want to win the battle, you have to know your enemy”. When it comes to bacterial infections, we often don’t know our enemy very well and we are losing. Despite our best efforts to combat Streptococcus pneumoniae infections, this opportunistic pathogen remains a serious threat to human health, killing over 826 000 children each year and causing severe illness in 14 million more. Mankind is therefore in desperate need of novel therapies that can eradicate S. pneumoniae infections. The search for these therapies, however, is impeded by the lack of insight into the life cycle of this important pathogen. In this proposal, I therefore aim to generate unprecedented insight into the S. pneumoniae cell cycle. I will do so by performing an innovative pooled CRISPRi (Clustered Regularly Interspaced Short Palindromic Repeats Interference) screen combined with FACS (Fluorescence Activated Cell Sorting) to assess the effect of downregulation of all S. pneumoniae genes on important cell cycle parameters such as cell morphology, DNA content and the formation of the Z-ring that is required for cell division. This genome-wide screen will reveal several gene products that are important for the correct progression of the S. pneumoniae cell cycle. I will further characterize the most promising targets to unravel their cell cycle-related function at the molecular level. Moreover, newly-identified gene products that are important for cell cycle progression could be interesting novel drug targets. The efficacy of these prospective targets will be validated in an in vivo infection model in Galleria mellonella (wax moth) larvae. In the future, these candidates can be used as a starting point for the development of novel and effective therapies. Besides generating valuable fundamental insight into the S. pneumoniae cell cycle, the results of this project will thus also assist in our fight against this notorious pathogen.

Keywords: streptococcus pneumoniae,cell cycle,crispri,cell division,chromosome segregation
Low frequency radio search and study of exoplanet magnetospheres and star-planet plasma interactions (EXORADIO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: France
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 2212500.0
EU funding (EUR): 2212500.0
Participants: 2
Project status: SIGNED

The project aims at expanding the planetology, exoplanets and space weather fields by obtaining the first confirmed detections and subsequent in-depth studies of radio emissions from exoplanets. Origin of the emissions can be the magnetosphere of the exoplanet or its plasma interaction with its parent star. Magnetospheres of Solar System planets are very diverse, although emerging from the same basic plasma physics laws. Better sampling the parameter space by exploring various stellar luminosities and winds properties, planetary magnetic fields, geometries of interaction, will allow us to identify fundamental processes and separate them from the specificities of each system, as was done earlier for the question of planetary formation. Although recent observations at 100-200 MHz from large modern radiotelescopes may be revealing the first star-planet plasma interactions, I show why our searches must concentrate at the lowest frequencies observable from the ground, 10 to 85 MHz, and why intense enough signal should exist at these frequencies. The world’s most sensitive instrument in this range, NenuFAR, of which I am principal investigator, is now operational, and I will use it to conduct the largest ever exoplanet search program at radio frequencies. The main analysis tools have been developed and tested on LOFAR data, and the frame for interpreting theoretically the detected signals is ready. I took a large part in all these developments. I am thus at the right place and time to get the detections that will open the new field of comparative exo-magnetospheric physics and exo-space weather, as well as open a new window to study exoplanets, their magnetic field, interior structure, rotation, inclination, the parent-star interaction, and even habitability. These revolutionary developments will usher a new era in astrophysics. While studying the northern low-frequency sky with NenuFAR, I will also prepare in a timely way our exploration of the southern sky with SKA.

Keywords: exoplanets,star planet interaction,magnetic field,magnetospheres,radioastronomy,low frequencies,space weather,habitability
Economic Development and Structural Transformation (EDST)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance and management
Countries involved: Spain,Spain
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-03-01
End date: 2024-02-29
Duration (months): 84.0
Total project cost (EUR): 1486500.0
EU funding (EUR): 554791.0
Participants: 2
Project status: SIGNED

The early development literature documented that the growth path of most advanced economies was accompanied by a process of structural transformation. As economies develop, the share of agriculture in employment falls and workers migrate to cities to find employment in the industrial and service sectors [Clark (1940), Kuznets (1957)]. In the first industrialized countries, technical improvements in agriculture favoured the development of industry and services by releasing labour, increasing demand and raising profits to finance other activities. However, several scholars noted that the positive effects of agricultural productivity on economic development are no longer operative in open economies. In addition, there is a large theoretical literature highlighting how market failures can retard structural transformation in developing countries. In particular, financial frictions might constrain the reallocation of capital and thus retard the process of labour reallocation. In this project, we propose to contribute to our understanding of structural transformation by providing direct empirical evidence on the effects of exogenous shocks to local agricultural and manufacturing productivity on the reallocation of capital and labour across sectors, firms and space in Brazil. For this purpose, we construct the first data set that permits to jointly observe labour and credit flows across sectors and space. To exploit the spatial dimension of the capital allocation problem, we design a new empirical which exploits the geographical structure of bank branch networks. Similarly, we propose to study the spatial dimension of the labour allocation problem by exploiting differences in migration costs across regions due to transportation and social networks.

Keywords: economic development,structural transformation,factor missallocation,credit market frictions
Animal coloration through deep time: evolutionary novelty, homology and taphonomy (ANICOLEVO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Ireland
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2016-01-01
End date: 2021-04-30
Duration (months): 64.0
Total project cost (EUR): 1562000.0
EU funding (EUR): 1562000.0
Participants: 1
Project status: CLOSED

What does the fossil record tell us about the evolution of colour in animals through deep time? Evidence of colour in fossils can inform on the visual signalling strategies used by ancient animals. Research to date often has a narrow focus, lacks a broad phylogenetic and temporal context, and rarely incorporates information on taphonomy. This proposal represents a bold new holistic approach to the study of fossil colour: it will couple powerful imaging- and chemical analytical techniques with a rigorous programme of fossilisation experiments simulating decay, burial, and transport, and analysis of fossils and their sedimentary context, to construct the first robust models for the evolution of colour in animals through deep time. The research will resolve the original integumentary colours of fossil higher vertebrates, and the original colours of fossil hair; the fossil record of non-melanin pigments in feathers and insects; the biological significance of monotonal patterning in fossil insects; and the evolutionary history of scales and 3D photonic crystals in insects. Critically, the research will test, for the first time, whether evidence of fossil colour can solve broader evolutionary questions, e.g. the true affinities of enigmatic Cambrian chordate-like metazoans, and feather-like integumentary filaments in dinosaurs. The proposal entails construction of a dedicated experimental maturation laboratory for simulating the impact of burial on tissues. This laboratory will form the core of the world’s first integrated ‘experimental fossilisation facility’, consolidating the PI’s team as the global hub for fossil colour research. The research team comprises the PI, three postdoctoral researchers, and three PhD students, and will form an extensive research network via collaborations with 13 researchers from Europe and beyond. The project will reach out to diverse scientists and will inspire a positive attitude to science among the general public and policymakers alike.

Keywords: fossil colour,fossil pigments,melanin,carotenoids,structural colours,3d photonic crystals,fossil feathers,fossil insects,decay experiments,diagenesis,taphonomy,evolutionary novelty,deep ho
REaching and grasping Training based on Robotic hybrid AssIstance for Neurological patients: End users Real life evaluation (RETRAINER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Advanced interfaces and robots: Robotics and smart spaces
Action type: Innovation actions
Partnership: Robotics SPARC (cPPP)
Countries involved: Austria,Germany,Italy,Germany,Italy,Germany,Switzerland
Call: Robotics (H2020-ICT-2014-1, 2014)
Start date: 2015-01-01
End date: 2019-03-31
Duration (months): 51.0
Total project cost (EUR): 3711964.11
EU funding (EUR): 2784831.0
Participants: 10
Project status: CLOSED

The aim of the RETRAINER proposal is to tune and validate advanced, robot-based technologies to facilitate recovery of arm and hand function in stroke survivors and to verify extensively the use of the system by end-users. RETRAINER will allow the users to use their own arm and hand as much and as soon as possible after the trauma so to achieve the best outcomes in rehabilitation. A continuous iterative process between the technology development and the testing feedback will drive the whole project. RETRAINER will implement a full technology transfer from the results of a previous FP7 project, MUNDUS, aimed at setting up a similar assistive device for severely disabled people in daily life activities. RETRAINER will make available two systems that could be used either combined or stand-alone. RETRAINER S1 will provide the end-user with a robot that does not completely take over the user’s tasks and substitute the functionality of the body, but specifically supports the user only whenever he/she really needs support. Residual functionality is trained and improved on rather than replaced by the robotic device. Arm movements will be supported by the combined action of a passive exoskeleton for weight relief and Neuromuscular Electrical stimulation (NMES) delivered to several arm muscles in a controlled manner. RETRAINER S2 will exploit a wearable NMES system with multiple arrays of electrodes for hand rehabilitation facilitating the grasping function. Both systems will benefit from use of interactive objects, i.e. daily-life objects able to supply information about themselves to drive usage. Within RETRAINER the same principle and module will be exploited to drive rehabilitation exercises and to monitor daily life. The systems will undergo a thorough randomized control clinical trial with end users to assess their efficacy in rehabilitation. Certification and qualification of the system will be pursued, given the adequate quality of experimental results.

Keywords: hybrid robotic rehabilitation system,stroke survivors,upper limb rehab,exoskeleton,wearable functional electrical stimulation,myocontrol neuroprosthesis,randomized control clinical trial
Mechanisms of sarcomeric protein homeostasis during physical exercise and ageing (REBUILD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-04-01
End date: 2019-03-31
Duration (months): 24.0
Total project cost (EUR): 185076.0
EU funding (EUR): 141203.25
Participants: 1
Project status: CLOSED

During ageing muscle fibers are constantly subjected to high forces resulting in mechanical stress on cells and proteins. As a consequence they can degenerate, leading to suboptimal force generation, lack of coordinated movements and ultimately to muscle failure in the elderly population. This ageing process that leads to a progressive loss of muscle function has a major health impact on the ageing Western society. Physical activity is known to delay this decline. The REBUILD project aims to determine the temporal dynamics of protein replacement during life of a muscle fiber by SILAC-based mass spectrometry and genetics. It will integrate biomechanics with muscle homeostasis and accurately quantify the impact of physical activity on protein turnover and investigate the physiological consequences for the ageing animal. By combining the power of genetics and SILAC-based proteomics with behaviour of free flight under defined exercise conditions, we create a unique position for a discovery orientated large-scale in vivo genetic screen. The interdisciplinary nature of the project will allow establishing novel hypothesis, combining muscle biomechanics as a driving force behind dynamic maintenance of the muscle tissue during ageing. The experienced researcher will expand on previous training acquired in San Francisco, USA, and establish a new line of research in the crossroads of two developing fields (quantitative proteomics and biomechanical regulation of tissue homeostasis). This will be a stepping stone for his scientific independence. The host will expand on its expertise on developmental regulation of muscle formation and benefit from the expertise of the candidate in the biology of ageing and homeostasis. A precise understanding of mechanisms that control homeostatic replacement of damaged proteins in muscle fibers should foster interventions aimed at maintenance of muscle capacity in older individuals and thus, an important step towards healthy ageing.

Keywords: muscle,drosophila
A EUROpean training and research network for environmental FLOW management in river basins (EUROFLOW)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,Italy,Germany,Germany,Germany,Spain,Italy,Norway,Switzerland,Slovenia,Switzerland,Norway,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2017-09-01
End date: 2022-02-28
Duration (months): 54.0
Total project cost (EUR): 3923988.84
EU funding (EUR): 3923988.84
Participants: 25
Project status: CLOSED

A EUROpean training and research network for environmental FLOW management in river basins The regulation of river flows is one of the biggest stressors affecting river ecosystems across the world. In many westernised countries, major legislative efforts are therefore underpinning the development of new approaches to mitigate the impacts of river flow regulation (e.g. EU WFD, US Clean Water Act, South Africa National Water Act, Australian Water Resources Act). These approaches are based on optimising the management of river flows to maintain services to humans (e.g. water supply, hydropower) whilst protecting and/or rejuvenating the aquatic environment with water of adequate quantity and quality in space and time (i.e. environmental flows, aka e-flows). In this context, a field of applied aquatic science has developed to generate the evidence base for identifying the best ways to manage the quantity, quality and patterns of e-flows to sustain river ecosystems. EUROFLOW will train a new cohort of researchers to be future leaders in this field.

Keywords: reservoir,flood,low flow,river,abstraction,water quality,freshwater biology