Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Exploring the dendritic molecular machinery responsible for neuronal polarization (SortAx)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2024-03-30
Duration (months): 24.0
Total project cost (EUR): 147815.04
EU funding (EUR): 147815.04
Participants: 1
Project status: SIGNED

The high morphological and functional polarization of neuronal processes relies on exquisite mechanisms to accurately sort and traffic proteins to their rightful location. It is therefore of no surprise that accurate formation and function of neuronal circuits depends on these trafficking mechanisms, which are indeed often impaired in neurodegenerative disorders and normal aging. During the past 30 years, researchers have been able to dissect the mechanisms required to target proteins to the dendritic plasma membrane, however our understanding of the mechanisms underlying the axonal polarization of proteins is rather incomplete. In this regard, a growing number of studies, including my work, suggests that dendritic endosomes are key sorting stations to direct neuronal cargoes to the axon. Yet, the molecular machinery of intracellular trafficking and endosomal sorting required remains to be uncovered. In this proposal, I hypothesize that dendritic endosomes are key sorting stations for polarization of axonal cargoes. I therefore propose to elucidate the key axonal trafficking pathways of endogenous cargoes, the intracellular trafficking and endosomal machinery involved and assess their importance for axonal development and connectivity. Importantly, I will adopt an unbiased approach using cutting-edge technology to focus on the endogenous protein pool, which differs considerably from prior studies in the field, in which axonal trafficking route has been followed for a limited number of cargoes under overexpression conditions. Given that abnormal axonal trafficking increases susceptibility to neurodegenerative diseases, including Alzheimer´s and Parkinson, with this project I will also contribute to the design of new therapies to alleviate neurodegeneration by deciphering the molecular mechanisms of axonal cargo trafficking.

Keywords: neuronal polarity,endosomes,intracellular trafficking,axon
Boosting Innovation for COVID-19 Diagnostic, Prevention and Surveillance. (INNO4COV-19)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Action type: Innovation actions
Countries involved: Spain,Ireland,Italy,Austria,Germany,Spain,Spain,Belgium,Belgium,Portugal,Portugal
Call: Medical technologies, Digital tools and Artificial Intelligence (AI) analytics to improve surveillance and care at high Technology Readiness Levels (TRL) (H2020-SC1-PHE-CORONAVIRUS-2020-2-CNECT, 2020)
Start date: 2020-10-01
End date: 2022-11-30
Duration (months): 26.0
Total project cost (EUR): 6247638.75
EU funding (EUR): 6188613.75
Participants: 11
Project status: SIGNED

The novel corona virus causing COVID-19 overwhelmed Europe and the world in just a few weeks’ time. Small and Medium-sized Entrerprises (SMEs are put at very high risk by the slowdown or shutdown of economic life in their countries – exactly those companies who ensure the development of innovative solutions urgently required for counteracting the impacts of COVID-19 and for helping to control possible future outbreaks alike. In view of this situation, accelerated uptake of innovative technologies to tackle COVID-19 is most needed. In order to give an efficient and fast answer to this challenging situation, we propose building an Innovation Hub for the addressed technologies: an innovative open access platform to offer companies and reference laboratories the capabilities, expertise, networks and services required for the assessment, development, prototyping, testing, scaling-up, pilot production and market exploitation of innovative technologies to tackle COVID-19 pandemic. This approach will be based in the Open Innovation Test Beds (OITBs) concept, to incorporate lessons learned from those Innovation Actions, reducing time for putting in place such HUB and ensuring its successful implementation for a swift impact to the current situation. Our approach will include leading applied research and innovation centers in Europe, together with entities specialized in building OITBs, and reference clinical sites. INNO4COV19 will provide funding to third parties to help them achieve the desired objectives. Presence of leading applied research EU institutions in the Consortium will help to obtain a huge impact and to find and attract innovators across Europe to offer new solutions for COVID-19 pandemic and other potential future outbreaks. Europe needs to reinforce its technological leadership and rebuild an industrial sector capable to protect our citizen’s safety and well-being, and INNO4COV-19 will help in catalyzing the change.

Keywords: covid 19,open innovation platform,key enabling technologies
3-Dimensional Maps of the Spinning Nucleon (3DSPIN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Italy,Italy
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-07-01
End date: 2020-12-31
Duration (months): 66.0
Total project cost (EUR): 1509000.0
EU funding (EUR): 1194000.0
Participants: 2
Project status: CLOSED

How does the inside of the proton look like? What generates its spin? 3DSPIN will deliver essential information to answer these questions at the frontier of subnuclear physics. At present, we have detailed maps of the distribution of quarks and gluons in the nucleon in 1D (as a function of their momentum in a single direction). We also know that quark spins account for only about 1/3 of the spin of the nucleon. 3DSPIN will lead the way into a new stage of nucleon mapping, explore the distribution of quarks in full 3D momentum space and obtain unprecedented information on orbital angular momentum. Goals 1. extract from experimental data the 3D distribution of quarks (in momentum space), as described by Transverse-Momentum Distributions (TMDs); 2. obtain from TMDs information on quark Orbital Angular Momentum (OAM). Methodology 3DSPIN will implement state-of-the-art fitting procedures to analyze relevant experimental data and extract quark TMDs, similarly to global fits of standard parton distribution functions. Information about quark angular momentum will be obtained through assumptions based on theoretical considerations. The next five years represent an ideal time window to accomplish our goals, thanks to the wealth of expected data from deep-inelastic scattering experiments (COMPASS, Jefferson Lab), hadronic colliders (Fermilab, BNL, LHC), and electron-positron colliders (BELLE, BABAR). The PI has a strong reputation in this field. The group will operate in partnership with the Italian National Institute of Nuclear Physics and in close interaction with leading experts and experimental collaborations worldwide. Impact Mapping the 3D structure of chemical compounds has revolutionized chemistry. Similarly, mapping the 3D structure of the nucleon will have a deep impact on our understanding of the fundamental constituents of matter. We will open new perspectives on the dynamics of quarks and gluons and sharpen our view of high-energy processes involving nucleons.

Keywords: hadronic physics,structure of the nucleon,spin of the nucleon,quarks and gluon,quantum chromodynamics,deep inelastic scattering,transverse momentum parton distributions
Multifunctional Spin Crossover Materials (SPINSWITCH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Spain,Ukraine,Romania,Moldova, Republic of,Romania,France
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2016, 2016)
Start date: 2017-01-01
End date: 2021-12-31
Duration (months): 60.0
Total project cost (EUR): 954000.0
EU funding (EUR): 954000.0
Participants: 7
Project status: CLOSED

This project deals with an exchange programme of seven research teams with the aim to establish and consolidate a network for the design of innovative multifunctional materials based upon iron(II) spin crossover complexes: their synthesis, magnetic and spectroscopic studies, investigations on their crystalline, liquid crystalline and morphological structures, pressure effects on spin crossover properties and, particularly, their implementation into pressure sensors. The synthetic part of this project aims to access novel types of crystalline and liquid crystalline spin crossover complexes, hybrid luminescent materials, photo-switchable liquid crystalline compounds, composites and nano-objects of original morphologies and transition characteristics. These switchable materials will become a matter of different experiments under pressure: magnetic and Mӧssbauer measurements under hydrostatic pressure and optical experiments in a gas pressure cell. This will allow to reach an important impact on the synthesis of new bistable materials, on their behaviour under pressure, and to make them an active part of different pressure sensors. The academic participants involved in this work have collaborated on joint projects and have co-authored several scientific papers. The two industrial institutions have a recognized expertise in organic and material synthesis, commercialization, as well possessing experience on elaboration of spin transition materials. The establishment of this joint exchange programme will promote and strengthen the complementarity of the participants and will stimulate cross-fertilization, thus forming an excellent centre of synergy in research, innovation and technology in the area of functional materials. This network offers a complete training in the synthesis and characterization of new spin crossover materials for various applications.

Keywords: spin crossover,composites,liquid crystals,fluorescence,switches
EXperimental Computational Hybrid Assessment of Natural Gas pipelines Exposed to Seismic Risk (EXCHANGE-Risk)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Germany,Italy,Italy,Germany,Austria,Greece,Greece,Norway,United States,Canada,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2015, 2015)
Start date: 2016-01-01
End date: 2019-12-31
Duration (months): 48.0
Total project cost (EUR): 909000.0
EU funding (EUR): 909000.0
Participants: 12
Project status: CLOSED

EXCHANGE-Risk is an Intersectoral/International Research and Innovation staff exchange scheme between academia and the industry in Europe and North America focusing on mitigating Seismic Risk of buried steel pipeline Networks that are subjected to ground-imposed permanent deformations. It also aims at developing a Decision Support System for the Rapid Pipeline Recovery to minimize the time required for inspection and rehabilitation in case of a major earthquake. EXCHANGE-Risk involves novel hybrid experimental and numerical work of the soil-pileline system at a pipe, pipeline and network level integrated with innovative technologies for rapid pipe inspection. The outcome of the project is a series of well targeted exchanges between the partners (involving more than 30 early stage and experienced researchers) within a well defined framework of innovation that ensures transfer of knowledge between the academia and the industry, Europe and North America as well wide dissemination of the methodologies and tools developed to the engineering community.

Keywords: natural gas pipelines,seismic risk,vulnerability,energy,energy supply,energy transmission,infrastructures,soil structure interaction,network analysis
NEW GENERATION OF BIPV-GLASS WITH ADVANCED INTEGRATION PROPERTIES (ADVANCED-BIPV)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-2-2014, 2014)
Start date: 2015-04-01
End date: 2017-03-31
Duration (months): 24.0
Total project cost (EUR): 2695887.5
EU funding (EUR): 1887121.25
Participants: 1
Project status: CLOSED

This project proposal starts to walk pursuing to accomplish the following main general objective: to overcome the main limiting factors of BIPV technology strengthening its competitiveness by developing new generation PV glazing satisfying the well-defined market demanded architectural trends. ONYX will face this main goal by developing a new family of products referred as Novel XL-BIPV glazing units, High-Mechanical Resistance PV units and high performing vision glazing based on PV thin film transparent panes (transparency over 50%) being market ready within the 24 forthcoming months. During the lifetime of the project, main challenges will be faced and overtaken by well-defined approaches. Out of the technical challenges ONYX will establish a very well defined commercialization and marketing strategy targeting global markets and main green building and architectural glazing stakeholders. ONYX ambition will be reaching the blue ocean concept. In other words, by developing BIPV products with undeniable added value achieving a clear market differentiation from our competitors leading to a greater range of coverage of the architectural glass industry, gaining the attention of prestigious end users as clients, and promoting a sense of market dominance by offering products that others cannot. The final goal will be achieving a 4,3% market share of the global BIPV business by 2020. It means to double or quadruplicate our actual share of 1% in a market that will grow from $823 million ($US) in 2014 to $2.7 billion in 2019 (30% growth/per year). On the other hand, it should be pointed out that this project proposal fits perfectly with general EU policies in terms of sustainability as for instance Energy Performance of Building Directives. In summary, by executing this project ONYX seeks to become a world leader not only in BIPV, but also in high-performing architectural glazing and Green Building Sector developing BIPV unique solutions.

Keywords: bipv,sustainable,see thru,resistance,dimensions,sizes
HELICITY: Evolution of correlated traits in response to city life: helicid snails as windows on the consequences of urban history (HELICITY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-06-01
End date: 2023-05-31
Duration (months): 24.0
Total project cost (EUR): 166320.0
EU funding (EUR): 166320.0
Participants: 1
Project status: CLOSED

Urbanization is one of the most dramatic land-use changes caused by humans, combining habitat fragmentation and loss, pollutions and increased temperature. While it causes numerous population declines in many species, others persist or even thrive in cities, possibly through evolutionary changes. In this project, I will study how urbanization shapes multivariate phenotypic evolution in such an organism, including not only life-history traits, movement strategies/space use… but their association into integrated phenotypes. As a central point, I will explicitly consider the oft-neglected temporal heterogeneity/ history of the urbanization process, comparing new and older urban neighbourhoods to see under which conditions organisms can adapt to city life fast enough. Using snails as models, this Action will combine advances in small animal tracking, statistical analysis and data science with state-of-the-art evolutionary ecology, to not only explore the mechanisms behind observed changes, but also potential consequences for relevant aspects of ecosystem functioning. This project will increase our understanding of the ecological consequences of evolution in response to human-caused environmental changes, helping fill major knowledge gaps noted by the IPBES. Through outreach, it will increase community engagement with (urban) biodiversity. Finally, by merging two of my long-standing research lines in a common, integrated project, through the acquisition of new scientific skills and training in project management, it will favour my establishment as an independent leader in the field.

Keywords: climate change,dispersal,functional ecology,quantitative genetics
Red and White: The Globalization of Wine in the Anthropocene (Red and White)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-11-02
End date: 2022-11-01
Duration (months): 24.0
Total project cost (EUR): 214158.72
EU funding (EUR): 214158.72
Participants: 1
Project status: CLOSED

The overarching question Red & White asks is how has science and technology been leveraged to expand the wine industry globally in the 20th and 21st centuries and how has that shifted the taste of the wines as the climate warms? Answering this question requires a set of interdisciplinary methods. My training in the history of science and technology as well as my work in sensory history (particularly my theory of a historical palate) only allows me to answer part of the question. To fully answer the question, I need to develop new skills in digital history and material culture studies that are firmly rooted in the environment, which is why UiS it the best place for me to train and carry out the project. Given its interdisciplinary focus and contemporary implications, Red & White will appeal to a number of diverse communities including academics, industry professionals, hospitality managers and the general public to better understand how the climate crisis is reshaping the industry and the flavor of wine across the globe.

Keywords: environmental history,sensory studies,material culture,digital history,business history,wine industry,globalization,industrialization,anthropocene,history of science,history of technology
Standardised approaches and products for the systemic retrofit of residential Buildings, focusing on HEATing and cooling consumptions attenuation. (BuildHEAT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Sustainable, resource-efficient and low-carbon technologies in energy-intensive process industries
Action type: Innovation actions
Countries involved: Germany,Germany,Germany,Spain,Spain,Italy,Italy,Germany,Italy,Italy,Austria,Italy,Italy,Italy,Belgium,Belgium,United Kingdom,United Kingdom
Call: Integrated approach to retrofitting of residential buildings (H2020-EeB-2015, 2015)
Start date: 2015-09-01
End date: 2020-02-29
Duration (months): 54.0
Total project cost (EUR): 9050448.25
EU funding (EUR): 6985013.25
Participants: 25
Project status: CLOSED

Heating consumption in the residential sector in Europe is around 2300 TWh/y, DHW consumptions reaches 500 TWh/y, while cooling consumption is less than 100 TWh/y. The construction sector offers unique opportunities to decarbonise the European economy. However, as the replacement rate of the existing stock is very small (1-1.5 % per year), acceleration is needed. On top of this, the reorganisation of the sector poses tremendous challenges due to its extreme fragmentation: more than 50% of the residential buildings are owned by private single owners. Moreover, whilst few major industrial players are active on the market, it is largely dominated (more than 95%) by SMEs both on the manufacturers’ and the professionals’ side. BuildHEAT addresses this challenging sector by: - elaborating systemic packages for the deep rehabilitation of residential buildings - developing innovative technologies facilitating the implementation of the renovation measures - developing financial tools enabling large public and private investments - involving the construction chain from the very beginning and all along the building life cycle. A set of reliable, energy efficient and affordable retrofit solutions will be mad available, which execution is facilitated by industrialised, modular and flexible HVAC, façade and ICT systems developed. Despite the affordability, innovative solutions are more expensive compared to off the shelf ones. Therefore financing models are needed to facilitate the massive entry to market of the new technologies. BuildHEAT aims to leverage large private investments by using European structural funds, thus promoting retrofit actions at quarter level. Finally, BuildHEAT involves the entire construction chain – from owners to professionals to investors – in the retrofit process and all along the lifetime of the building, by addressing technical, behavioural, cultural and economic perspectives. In this way, awareness and involvement are triggered.

Keywords: renewable heating and cooling,waste heat recovery,reversible heat pump,diffuse storage,control strategies,district level,active fa ade systems
Capturing and quantitative analysis of multi-scale multi-channel diagnostic data. (CARDIALLY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Italy,Russian Federation,Serbia,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2015, 2015)
Start date: 2015-11-01
End date: 2019-10-31
Duration (months): 48.0
Total project cost (EUR): 234000.0
EU funding (EUR): 234000.0
Participants: 4
Project status: CLOSED

We are proposing a four-year programme of knowledge transfer between Aston University (ASTON, UK), Universita Degli Studi Di Brescia (UNIBS, Italy), Diasens (Diasens, Serbia), and Novosibirsk State University (NSU, Russia). The aim of our interdisciplinary proposal is to bring together the unique expertise of participants to solve the important and challenging problem of heart failure prediction and diagnostic. Our transformative approach combines advanced methods of complex data analysis and novel diagnostic technologies to prevent highly damaging consequences of this deadly and disabling disease. Strong interdisciplinary nature of the project and a balance of industrial applications and fundamental science ensure a wide range of skill and knowledge transfer within the consortium. Working in close collaboration with our SME partner will allow early career researchers to gain an invaluable experience in bringing research to real life applications and to broaden their future career choices. The research has significant potential for life-changing applications in cardiology, especially relevant to adult and aging population. Solution to this problem will help to cut costs in European health care systems and improve quality of life of millions of people.

Keywords: nonlinear time series,statistical analysis,fibre based sensors,diagnostic data analysis,heart failure