Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Flexoelectric control of magnetic textures in 2D oxide membranes (FLEXOMAG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 2
Project status: SIGNED

Freestanding layers of complex oxides are a completely new generation of 2D materials which exhibit a plethora of coupled responses and endow 2D materials with robust correlated groundstates. In this project we explore the control of magnetism in a freestanding oxide driven by the coupling of its ferromagnetic groundstate to strain induced polar structures enabled by the freestanding form. Deterministic control of magnetic textures (namely skyrmions) is an exciting area of research for its potential to impact computing and information technology. However, the metallic nature of most ferromagnetic materials renders the direct control by electric fields impractical due to screening by free carriers. Developing approaches to direct electric control of ferromagnetism in a single material remains a virgin land to explore. FLEXOMAG aims at the use of strain induced flexoelectricity in a metallic oxide with strong spin orbit interaction (SrRuO3) to nucleate spin textures, skyrmions and skyrmion lattices. Flexoelectricity enables the creation of a polar structure in the presence of strain gradients, and is expected to impact magnetic ordering via direct coupling of spins with a polar structure by spin-orbit coupling. Moreover, strain gradients will act as effective electric field and would not suffer from the cancellation by screening due to free charges. Flexoelectric control of magnetism is in itself an important breakthrough in fundamental science and it will further yield a completely novel strategy to tailor spin textures. We will use twistronics of 2D oxides to design skyrmion lattices never observed before in oxides. Skyrmions and skyrmion lattices are acclaimed information vectors sought in the design of next generation magnetic memories. This research will supply a long sought technological platform to fabricate skyrmions by design.

Keywords: flexoelectricity,twistronics,skyrmions,complex 2d oxides,membranes
Testing, improving, and co-creating Guidance and Tools for Real World Evidence Generation in Europe and use for Decision-Making in Europe: GREG (GREG)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Innovative Health Initiative
Action type: Research and Innovation actions
Partnership: IHI (JU-JTI)
Countries involved: Netherlands,United Kingdom,Spain,France,Portugal,Norway,Denmark,Germany,Belgium,Sweden,United States,Italy,United Arab Emirates,Canada,Switzerland,Greece,Ireland
Call: Development of evidence based practical guidance for sponsors on the use of real-world data / real-world evidence (HORIZON-JU-IHI-2024-06-two-stage, 2024)
Start date: 2025-05-01
End date: 2030-04-30
Duration (months): 60.0
Total project cost (EUR): 26260122.4
EU funding (EUR): 13298375.0
Participants: 56
Project status: SIGNED

Europe generates real world health data (RWD) that has the potential to inform the development and evaluation of medicines and medical devices. However, multiple barriers remain that limit the access, analysis, interpretation, and use of RWD, hampering its use. Additionally, the limited uptake of existing guidelines for the generation and use of real world evidence (RWE) adds complexity in the use of RWD to inform decision making. The GREG consortium will leverage the learnings of previous and ongoing key RWE initiatives to fill these gaps by generating, pilot-testing, and disseminating evidence-based guidance and tools for the use of RWE to inform the development and evaluation of medicines, medical devices, and combinations. To achieve these goals, we will work with key stakeholders to iteratively test and improve our guidance and tools, backed by case studies from previous successful and unsuccessful examples. We will engage with the most relevant European RWE initiatives and access the largest network of RWD partners in Europe, namely the European Health Data and Evidence Network (EHDEN) through our partner, the EHDEN Foundation. Additionally, we will provide multi-stakeholder gatherings (including patient and public representatives) to promote the dissemination, adoption, and implementation of RWE for decision-making in Europe. Our public and private partners will co-create use cases working closely with key regulatory and health technology experts in bespoke fora. These will be used initially to evaluate existing guidelines, and later to pilot-test the GREG guidance and tools. Our outputs will include training for all involved stakeholders on the use of our guidance and tools, and practical templates to facilitate regulatory and health technology/payer submissions. Together, these will accelerate access to better medicines and medical devices for European citizens.

Keywords: real world data,real world evidence
Electrode assembly from floating nanowires for sustainable next generation batteries (Electrofloat)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2023-04-01
End date: 2024-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

“It is estimated that Europe needs an installed capacity for lithium-ion battery production of 300 GWh/year by 2030. By then, the battery market for electric vehicles alone will be worth $116 billion annually. Amongst many technical challenges in this transition is to develop cost-effective and environmentally sustainable processes methods to manufacture high silicon (Si) content anodes for the next generation LIBs (3b and 4a). Si is more abundant than graphite and can enable higher power batteries with thinner electrodes as well as extending the range of EVs by increasing energy density of the next generation of LIB cells by over 50%. ELECTROFLOAT proposes a new method to produce high capacity lithium ion battery anodes made of nanostructured silicon fabrics with up to 100 w.t% Si content, which eliminates all solvents, polymers and mixing steps from anode manufacture. This project comprises a set of selected R&D activities in key areas to reach TRL7 and start pilot-plant scale up, focused on a) de-risking the manufacturing process, b) application of strategies to mitigate capacity fading and increase electrochemical performance under application operational conditions c) designing scale-up roadmap to 1GWh/a and carrying out a techno-economic analysis to determine projected manufacturing costs and establish an adequate validation-driven scale-up strategy. Non-technical activities will be conducted by an Industrialisation Development Team consisting of the PI, two external industrialisation advisors, IMDEA’s Technology Transfer officer, and the CEO of Floatech, the newly created spin-off company pursuing commercialization of this technology.”
Stratification and the Segregation of Teachers in Education Markets (SegrEd)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Finland
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2025-12-01
End date: 2030-11-30
Duration (months): 60.0
Total project cost (EUR): 1499835.0
EU funding (EUR): 1499835.0
Participants: 1
Project status: SIGNED

There is concern on the European level about the diminishing attractiveness of teaching as a profession, as well as about the shortage of qualified staff in schools and the increasing turnover of teachers in segregated education markets. However, analyses of both teacher segregation, i.e., the regionally uneven distribution of qualified staff in affluent, mixed and disadvantaged schools, and the stratification of the teaching profession, i.e., teachers with different social-class backgrounds, have attracted relatively little attention. Many countries are struggling to provide equal access to quality education for all children. The academic community is currently engaged in four parallel debates on inequalities: 1) the stratification of education markets, 2) the socio-spatial (regional) segregation of schools, 3) the socio-economic segregation of schools and 4) the segregation of teachers. There appears to be no shared conceptual framework for empirical analysis, thus there are gaps in the current understanding of how educational inequalities arise. In addressing these gaps, the SegrEd project is developing a comprehensive research approach to scrutinising conceptual and empirical debates on stratification and the segregation of teachers. On the empirical level it explores how, why and with what societal consequences stratification and segregation among teachers emerge in education markets in Finland, France and Sweden. How does this segregation reproduce, reinforce or reduce existing inequalities between social groups? SegrEd renews the academic debate and proposes a novel conceptual tool, namely the social space of educational choice, which facilitates the simultaneous conceptual and empirical exploration of stratification and segregation. A multilevel, comparative methodological strategy combining quantitative and qualitative methods advances this approach. The aim is to arrive at an in-depth understanding of educational inequalities and their construction.

Keywords: segregation,stratification,sociology of education,social class,teacher
NEXT GENERATION MODULAR SIC-BASED ADVANCED POWER ELECTRONICS CONVERTERS FOR ENHANCED RENEWABLES INTEGRATION INTO THE GRID (SiC4GRID)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Belgium,Denmark,Switzerland,United Kingdom,France,Greece,Spain
Call: Demonstration of advanced Power Electronics for application in the energy sector (HORIZON-CL5-2021-D3-02, 2021)
Start date: 2022-10-01
End date: 2026-09-30
Duration (months): 48.0
Total project cost (EUR): 4657167.5
EU funding (EUR): 3787065.5
Participants: 13
Project status: SIGNED

SiC4GRID is a 48-months project gathering partners from the complete value chain of SiC-based converters collaborating to tackle current obstacles to the technologies' market uptake. SiC4GRID thus aims for an optimised integrated SiC-based technology composed of three-fold innovations in terms of hardware, software and IoT. Indeed, to optimise both techno-economic and environmental pillars, the consortium will design, produce, test and validate an integrated product composed of a 30% smaller size energy-efficient SiC-based power module competitive with state-of-the-art technology and coupled with an adapted optimised self-healing energy management system (EMS). This EMS amplifies the benefits of a strong system-level IoT architecture and adapted digital tools such as digital twin and optimisation algorithms. Throughout the project, the circularity and eco-design of all steps of the converter manufacturing process will be targeted with a strong emphasis on resource optimisation and carbon emission reduction. The testing phase will be done both as an integrated modular converter on a physical test bench, as well as digitally to increase the variety of relevant applications and real-condition scenario. For the digital simulations, three use cases will therefore be chosen to increase the validated parameters and scope of applications, including MMC and SST converters, onshore/offshore wind and PV applications, as well as the potential for storage. Overall, the project contributes to advancing the market readiness of the technology by lowering its cost (30% cost reduction compared to silicon converters), its size (15% size reduction), its lifetime (30+ years) and its environmental impact (30% resource consumption reduction and 50% CO2 emission reduction). In the longer-term, SiC4GRID will thus also help renewable energies integrate the energy grid and bring European leadership to the forefront of converter technology providers.

Keywords: sic converter sic power module offshore onshore systems mmc topology sst converters
Posthuman Music: Creative Practices after AI and Blockchain. (PosthumanMusic)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Studies of Cultures and Arts
Panel description: Social anthropology, studies of cultur es, stud ies of arts
Countries involved: Belgium
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Artificial Intelligence (AI) and blockchain technologies are becoming increasingly intertwined with human creativity, leading to novel forms of ‘posthuman’ musical expression that decentralize traditional notions of creative agency, authorship, ownership, and the ontology of the artwork. This poses unprecedented challenges and opportunities for new creative practices that need to be investigated, both scholarly and artistically. This project explores the transformative impact of AI and blockchain on contemporary musical practices, investigating the evolving concept of Posthuman Music as a forward-looking perspective that brings together human and non-human creative agents. Through analysis of existing practices and experimental prototyping, this project aims to forge new conceptual frameworks and craft new creative tools to enhance emerging posthuman creative practices. Combining theoretical investigations with practice-based research across four Research Strands (RS) unified by a common interdisciplinary research field, the project focusses on: investigating the ontological and conceptual consequences of AI and blockchain for music (RS1); developing digital media frameworks for situating posthuman musical practices (RS2); creating innovative compositional tools and techniques using AI and blockchain (RS3); experimenting with smart contracts in music through an experimental Creative Lab, generating new works and prototypes (RS4). Outputs include monographs, papers, conferences, compositions, digital performances, NFTs, experimental toolkits, and a dedicated web platform. Led by an experienced ERC Principal Investigator and an international team from musicology, music philosophy, composition, digital media studies, and computer science, the project will develop innovative creative practices, transforming music concepts for the digital era. Supported by a seasoned advisory board, the project will adapt to evolving conditions, ensuring cutting-edge research.

Keywords: music composition music philosophy posthumanism assemblage theory art ai blockchain practice based research
Multicore fiber Applications and TeCHnologies (MATCH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Portugal,France,Spain,Germany,Israel,Denmark,Italy,Belgium,United States
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 3666632.91
EU funding (EUR): 3450657.6
Participants: 15
Project status: SIGNED

Multicore fiber Applications and TeCHnologies (MATCH) is a doctoral training network proposed by a multidisciplinary and intersectoral consortium of international experts. This network directs PhD research toward multicore fibre (MCF) technology, which is recognized as the leading solution for scaling future optical fibre communication networks towards emerging information capacities, while offering the potential to lower costs, reduce power consumption and significantly boost network capacity by over tenfold while remaining as compatible as possible with current infrastructure. The MATCH programme outlines a comprehensive set of research and training objectives tailored to 13 doctoral candidates (DCs). The cohort of DCs will be hosted by 16 partners (11 from academia and 5 from the industrial sector) with exposure to cutting-edge optical fibre technology/photonic device realization/communication system engineering, and with training by leading fellows in MCF expertise worldwide. The planned training activities of DCs include 32 secondments, 7 mini-symposiums, 3 transferable skills workshops, summer schools, and tutorials, among others. In MATCH program, DCs will acquire expertise in diverse areas, encompassing (i) design and fabrication of MCFs with transmission capacities surpassing the state-of-the-art; (ii) design and implementation of MCF components and subsystems, with a focus on optical amplifiers and switches, multiple frequency comb sources, and parallel-scalable signal processing architectures; (iii) development and implementation of machine learning techniques for end-to-end performance optimization of MCF networks; and (iv) design and evaluation of coexistence of telecom and non-telecom signals in MCF networks. By engaging the expertise of MATCH academic and industrial partners, DCs will acquire distinct skills and knowledge to transform them to globally-minded scientists and engineers, who will help to shape Europe’s ICT future and societal wellbeing.

Keywords: multicore fibre,optical network,sensor,machine learning,optical amplifier,network node,switch,crosstalk,photonic integrated circuit,multiple frequency comb source,multicore fibre coupling
Improving understanding of lung immunity in tuberculosis to establish a diverse, innovative TB vaccine pipeline targeting mucosal immunity (TBVAC-HORIZON)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: Netherlands,France,Germany,Spain,Switzerland,United Kingdom,Italy,Denmark
Call: Vaccines 2.0 - developing the next generation of vaccines (HORIZON-HLTH-2022-DISEASE-06-two-stage, 2022)
Start date: 2023-04-01
End date: 2027-03-31
Duration (months): 48.0
Total project cost (EUR): 7110650.0
EU funding (EUR): 6183822.0
Participants: 20
Project status: SIGNED

Tuberculosis (TB) remains one of the most devastating infectious diseases worldwide, killing over 4,000 people every day. Prevention of tuberculosis infection by novel vaccines would provide the most cost-effective approach to achieve the goals of the WHO End TB strategy and the Sustainable Development Goals of the United Nations. While there are few promising TB vaccine candidates available, innovation by new platforms and strategies is needed to ensure that the most effective and affordable vaccines are developed. TBVACHORIZON will innovate and diversify the global TB vaccine pipeline by pursuing four objectives: 1. Define the composition, spatial organisation and functioning of protective immune responses in the Mycobacterium tuberculosis-infected lung. 2. Evaluate whether mucosal re-vaccination with BCG and other live attenuated vaccines improves protective efficacy against tuberculosis infection in mice, non-human primates and humans. 3. Identify host immune response profiles and biomarkers of natural and vaccine-induced immune protection in the lung. 4. Support next generation TB vaccine development by standardised head-to-head testing of selected vaccine candidates in animals and the establishment of novel delivery systems, adjuvant formulations and GMP platforms for live attenuated vaccines. TBVACHORIZON will increase our understanding and develop tools pertaining to immune protection in the lung, the major site of tuberculosis infection. This knowledge will be exploited to develop mucosal strategies for translating towards clinical evaluation and possible implementation. The interwoven activities will consolidate Europe’s leading role in TB vaccine research and innovation, with the ultimate goal of accelerated availability of affordable, accessible and more effective TB vaccines.

Keywords: tuberculosis,vaccines,novel approaches,platform technologies,immune protection,
Deciphering the role of the blood-brain barrier in uremic toxins-induced neuropathies (BBB-UT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-05-01
End date: 2025-04-30
Duration (months): 24.0
Total project cost (EUR): 187624.32
EU funding (EUR): 187624.32
Participants: 1
Project status: CLOSED

Chronic kidney disease (CKD) is estimated to affect more than 840 million people worldwide constituting a major global health crisis. Clinically, the number of CKD patients will continue to rise mostly because of the ageing population and the increased prevalence of comorbidities such as diabetes and hypertension. In Europe, around 100,000 million people are affected by it. According to the gloomy predictions, Europe is at risk of a dismal increase of CKD patients as well as costs to healthcare systems. Patients with advanced CKD display a loss of kidney function leading to a blood accumulation of, a.o. protein-bound uremic toxins (PBUTs) that are poorly eliminated by renal replacement therapies. This systemic retention known as the uremic syndrome affects other organs. Indeed, neurologic complications such as blood-brain barrier (BBB) disruption have been reported in CKD patients. The BBB guarantees the exchange between the blood and the brain through a complex cellular organization and a diverse range of transport proteins mediates the movement of endo/exogenous compounds. I hypothesize that impairment of kidney tubular functionality in CKD causes an alteration of BBB integrity and function. This results in an aberrant BBB pass-through of PBUTs as well as impacts BBB vectorial transport capabilities. This fellowship aims to develop an appropriate multi-organs-on-chip device to accurately describe (i) the impact of PBUTs on BBB integrity and functionality, and (ii) the involvement of kidney-brain axis dysfunction in PBUTs-driven BBB disruption. We will develop a bioprinting-based microfluidic BBB-on-chip to accurately study BBB permeability, architecture, and transport function. This device will be connected to our established proximal tubule-on-chip to form a robust (kidney-brain) multi-organs-on-chip system. This project will pave the way toward the establishment of new and effective CKD therapies, and an expert system for pharmacology studies in a near future.

Keywords: kidney brain crosstalk multi organs on chip biofabrication membrane transporters uremic syndrome blood brain barrier