Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Adolescents, Parents and Digital Media: Looking for the pattern that dis/connects (AdoDigitFamX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2017-08-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

This project will use a trans-disciplinary framework of social and developmental psychology and media and communications and the innovative methods of the First Person Perspective and Digital Ethnography to address existing gaps in research into the use of Information Communication Technologies, child development and family communication. Commenting upon research in the field, the recent report www.eukidsonline noted a prevalence of studies based on quantitative methods and a neglect of focus on mobile, convergent and emerging technologies. It also identified a persistent focus on risks and harm rather than opportunities and benefits and the lack of information on the role of adults, safety mediation and their effectiveness. This project fills these gaps by: (1) capturing the actual practices of adolescents with ICTs; (2) understanding how ICTs, family communication and parenting mutually shape one another; (3) exploring the opportunities and risks of ICTs for family and child development and the role of parents as safety mediators. A minimum of ten families with at least one adolescent child aged 13-16 will be recruited through Italian secondary schools to participate in the research which will involve data gathering via micro cameras (subcams) and video-interviews. Our innovative methods will provide new knowledge on: parents’ and adolescents’ individual and interpersonal practices in relation to ICTs; the goals, motives, representations and emotions underlying these practices and ICTs mediation processes in everyday family life. The implications of ICTs use for families and children’s health will also be considered. The results will be disseminated to socio-educational and clinical agencies, policy makers, and the general public. The fellowship will be hosted by the Department of Social Psychology at the London School of Economics and Political Science, a pioneer in Digital Ethnography and co-supervised by the Department of Media and Communications.

Keywords: information and communications technologies icts,family relations,adolescence,digital ethnography,communication processes,everyday life,video,qualitative research
Interactome of surface proteins important for Plasmodium sporozoite gliding motility (InteractomeMalMot)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-15
End date: 2017-05-14
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

Sporozoites are the motile forms of the malaria causing parasite Plasmodium and are injected into the vertebrate host by a mosquito. Their motility is powered by the parasites own actin-myosin motor, which is connected to transmembrane proteins of the TRAP (thrombospondin-related anonymous protein) family which serve as force transmitters. This substrate-dependent locomotion is a prerequisite for tissue penetration and host cell invasion. The glycolytic enzyme aldolase was thought to be the link between actin and surface adhesins (reported in Mol Cell). However, recent data revealed that aldolase does not fulfil this role hence it is now unclear how the force is transmitted. Additionally, lack of the main surface adhesin TRAP was also found (by the host lab) to not block motility as previously reported (in Cell). Additional recent findings are challenging the model of how gliding motility works and thus highlight the importance to focus on novel proteins. One such new protein, LIMP has recently been identified in the host lab. Therefore, the principal aim presented in this proposal is the identification of the molecular function of LIMP, which shows an identical phenotype to TRAP. To this end I will generate a series of parasites strains expressing different mutated versions of LIMP which will be investigated using biophysical approaches. Moreover, I attempt to identify the proteins interacting with LIMP.
Multi-functional Computational Microscopy for Quantitative Cell Tracking (MCMQCT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Israel,United States
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-08-01
End date: 2018-07-31
Duration (months): 36.0
Total project cost (EUR): 263385.0
EU funding (EUR): 263385.0
Participants: 2
Project status: CLOSED

Quantitative assessment of cellular phenotypes can result from various processes such as genetic manipulation, gene silencing, drug application or environmental changes. In many biological processes evident development of phenotypes often requires a long-term study of the sample, which can capture events at high-resolution and high frame rates. The essential working tool for this kind of studies is the optical microscope, which is essentially limited by a small field of view of the sample in two-dimensional (2D) environment, unsuitable for the quantitative assessment of cells in a more natural environment, in which they develop and evolve within complex communities. For this task, I purpose a novel platform based on a holographic on-chip microscopy which represents a new generation of computational microscopes, by integrating transformative technologies, which will ultimately enable five-dimensional, photodamage optimized at diffraction limited resolution, quantitative cell tracking. We believe that these functionalities and the platform's cost effectiveness will enable next generation high-throughput scientific research on the influence of drugs, genome modification and environmental changes, developing new models for cell locomotion, such as viral plague growth assays performed in hospitals and clinics, detection of parasites and bacteria in food/water and for education purposes, including in developing countries.

Keywords: quantitative cell tracking
Navigation of Airborne Vehicle with Integrated Space and Atomic Signals (NAVISAS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Switzerland,Slovakia,France,Portugal
Call: Communication,Navigation and Surveillance (CNS) (H2020-SESAR-2015-1, 2015)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 890910.0
EU funding (EUR): 584978.75
Participants: 4
Project status: CLOSED

Global Navigation Satellite System Positioning, Navigation and Timing (PNT) services have been increasing the airspace capacity, efficiency and safety and continue to proliferate and support more and more performance-based navigation operations. In the event of GNSS interference or outage, many GNSS enabled PNT services will be lost and the existing legacy navigation aids (VOR, DME, NDB and Secondary Radar) do not meet performance requirements nor maintain adequate capacity and efficiency. Therefore, a disruption to air traffic operations is expected to occur. Due to this disturbing reality and considering the growth of the worldwide air traffic, continuous, robust/resilient and high precision alternative positioning, navigation and timing (APNT) services and technologies are needed to maintain flight operations with the required level of performance while ensuring safety and security. Current solutions for APNT comprise of ground-based infrastructures transmitting non-GNSS signals-in-space to avionics. However, all these solutions cannot be used by small aircraft without major reengineering of their avionic systems. The NAVISAS Consortium will propose a novel concept of APNT for small aircraft that will integrate novel technologies and will merge multiple navigation avionics into one with no major impact on avionics. Specifically, NAVISAS is devoted to combine multiple GNSS constellations (GLONASS, GPS and Galileo) and a novel concept of atomic micro-gyroscope based on atomic spin and nuclear magnetic moment precessions, and to assess the improvements in performance and security. The technology of these gyros relies on a similar cell used for miniature atomic clocks, and will allow bridging the gap between the price of navigation grade gyroscopes and the market constraints for affordable non-inertial navigation systems and avionics in small aircraft, thus contributing significantly to enhancement of the flight safety level.

Keywords: apnt,gnss,glonass,atomic micro gyroscope,miniature atomic clocks,combining multiple gnss and imus
TOWARD A PHILOSOPHICAL RETHINKING OF TRANSLATION: Effects of Translation in a Contemporary European Space (TRANSPHILEUR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-08-01
End date: 2020-10-16
Duration (months): 24.0
Total project cost (EUR): 168277.2
EU funding (EUR): 168277.2
Participants: 1
Project status: CLOSED

This research project deals with the phenomenon of translation in order to investigate its philosophical structure, logic and character and thus to contribute to the affirmation and development of the philosophy of translation as a relevant research discipline. The research proposes a conception of translation as a self-reflexive transformational practice, investigating at the same time importance and effectiveness of translation in the contemporary European political and cultural context. The interdisciplinary character of the project requires a combination of philosophy, translation studies, cultural theory and political theory. The research aims to have a broad impact and takes into account the practical effectiveness of its main ideas for addressing some of the current social and political issues in Europe. The proposal includes training-through-research at the participating organisations, acquirement of new experiences and skills, a two-way-transfer of knowledge, teaching, organization of a workshop, participation in conferences, and planning for publications. Results will be disseminated to the academic community of experts and to the wider audience as well. The project is in line with the key priorities of the Horizon 2020 Work Programmes 2016-17 and 2018-20, i.e., with the integration of social sciences and humanities in promoting the European Public and Cultural Space.

Keywords: philosophy of translation,translation theory
FAIRplus (FAIRplus)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Public-private partnerships
Destination: Innovative Medicines Initiative 2
Action type: Research and Innovation actions
Partnership: IMI2 (Art-187)
Countries involved: Germany,Germany,Germany,Spain,Germany,Switzerland,Belgium,Sweden,Switzerland,France,France,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom,Luxembourg,United Kingdom,United Kingdom,United Kingdom
Call: FAIRification of IMI and EFPIA data (H2020-JTI-IMI2-2017-12-two-stage, 2017)
Start date: 2019-01-01
End date: 2022-12-31
Duration (months): 48.0
Total project cost (EUR): 7827194.0
EU funding (EUR): 3996150.0
Participants: 23
Project status: CLOSED

Wide sharing of knowledge and data drives the progression of science. Shared data allows other researchers to reproduce findings and benchmark quality of experiments. Sharing data so that other researchers can Find, Access and Interoperate – i.e. integrate the data with the outcomes of their own experiments - allows Reuse and an opportunity to build the large aggregated cohorts we need to detect rare signals and manage the many confounding factors in translational research. This project will develop the guidelines and tools needed to make data FAIR. Through worked examples using IMI and EFPIA data and application and extension of existing methods we will improve the level of discovery, accessibility, interoperability and reusability of selected IMI and EFPIA data. In addition, through disseminated guidelines and tailored training for data handlers in academia, SMEs and pharmaceuticals, data management culture will change and be sustained and datasets will be reused by pharmaceutical companies, academia and SMEs. Our FAIR SME & Innovation programme will enable wide data reuse and foster an innovation ecosystem around these data that power future re-use, knowledge generation, and societal benefit. We call this approach ‘FAIRplus’.

Keywords: fairification,fair,fair cmmi
COMORBIDITY MECHANISMS OF ANXIETY AND PARKINSON’S DISEASE (AND-PD)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Understanding health, wellbeing and disease
Action type: Research and Innovation actions
Countries involved: Israel,Spain,Italy,Spain,Sweden,France,France,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Understanding causative mechanisms in co- and multimorbidities combining mental and non-mental disorders (H2020-SC1-2019-Two-Stage-RTD, 2019)
Start date: 2020-01-01
End date: 2024-06-30
Duration (months): 54.0
Total project cost (EUR): 5995848.62
EU funding (EUR): 5995848.62
Participants: 12
Project status: SIGNED

AND-PD investigates causative mechanisms of anxiety (with or without depression) as a non-motor co-morbidity of Parkinson’s Disease (PD) and aims to understand the functional and pathological changes in the brainstem resulting from PD. This will provide new insights to advance personalised treatment of PD patients and open new research avenues supporting prevention, diagnosis and management of co-morbidities in PD patients. Using models of mental comorbidities of PD, AND-PD will investigate functional changes in brainstem nuclei and establish the link with the anxiety phenotype. Findings will be used to inform pre-clinical (rodent, non-human primate and biobank samples) and clinical research (fMRI and PET imaging, behavioural analysis, retrospective cohort analysis) to identify and correlate causalities between dysfunctional neurocircuitry and co-morbid anxiety of PD. To prove causality, AND-PD will i) analyse anxiety in neurotoxin and genetic models of PD; ii) assess the physiological impact and behavioural effects of interventions that selectively reproduce the damage caused by PD in the brainstem; and iii) determine the ability of RNA based approaches to counteract anxiety associated with PD. To demonstrate the link in human patients, AND-PD will analyse patient databases and correlate measures of anxiety with: 1) signs of neuropathology in PD brain samples’ brainstem and 2) clinical and functional biomarkers of dysfunctional neurotransmission through brainstem imaging in patients. AND-PD beneficiaries’ experience in translational research will help ‘bridge the gap’ between preclinical and clinical experiments and help identify new anatomical targets and markers (molecular, functional and pathological,) to support better diagnosis, management and treatment of co-morbidities in PD patients.

Keywords: non motor symptoms,anxiety,parkinson s disease,dorsal raphe nucleus,dopamine,neurophysiology,brain imaging
Veterinarization of Europe? Hunting for Wild Boar Futures in the Time of African Swine Fever (BOAR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Czechia
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-07-01
End date: 2025-06-30
Duration (months): 60.0
Total project cost (EUR): 1999875.0
EU funding (EUR): 1999875.0
Participants: 1
Project status: SIGNED

This project proposes a collaborative, ethnographic investigation of the relationship between three understudied subjects in anthropology: veterinary medicine, European hunting and wild boars. In recent decades, the wild boar has proliferated, (re)conquering the natural, rural and urban landscapes of Europe, and increasingly clashing with human practices and worlds. Classified as a game animal, the boar is primarily killed and managed by recreational hunters. Yet, hunters are proving incapable of stemming the tide of this intelligent, adaptable being, an interspecies relation that challenges hunting’s value and legitimacy in European society. This tension has amplified with the arrival of African Swine Fever (ASF) to the continent: a fatal virus that travels between wild boar and domestic pig, forest and farm, and threatens to infect and ruin the pig industry. In the name of biosecurity, and informed by veterinary knowledge, some States have intervened and conducted mass culls, erected dividing fences across Schengen space, or instituted no-go zones. During this crisis we witnessed how veterinary medicine’s role can extend beyond mediating human-animal relations, and work to structure and govern human lives in general. At the intersection of boars, hunting, ASF and veterinary medicine, this project has two main objectives: first, to examine how European hunting and porcine futures are intertwined, and the role of veterinarians in shaping these futures, and; second, through human-boar relations, study how society is becoming increasingly veterinarized and thus shape the conceptual and methodological development of the emerging field of veterinary anthropology. This project will further contribute to anthropology by opening a novel empirical and theoretical niche for the anthropology of hunting, and experiment with ethnography as a tool of engagement with near futures. The emerging and uncertain impact of ASF in Europe is an excellent moment to conduct such a project.

Keywords: veterinary anthropology,ethnography,hunting,wild boar,human animal relations,naturecultures,europe,african swine fever
CONSULTATION FORUM FOR SUSTAINABLE ENERGY IN THE DEFENCE AND SECURITY SECTOR - PHASE III (CF SEDSS III)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Belgium
Call: Support to the initiative on sustainable energy in the defence and security sector (H2020-IBA-SC3-Support-2019, 2019)
Start date: 2019-10-01
End date: 2024-09-30
Duration (months): 60.0
Total project cost (EUR): 3200000.0
EU funding (EUR): 3200000.0
Participants: 1
Project status: SIGNED

To address the emerging and future challenges in the field of energy as well as to meet the expectations of the Council of the European Union (EU), and consequently of the EU Ministries of Defence (MoDs), the Consultation Forum for Sustainable Energy in the Defence and Security Sector (CF SEDSS) will continue pursuing in Phase III the implementation of the EU legal framework on energy and will reaffirm the Consultation Forum as an appropriate vehicle for sharing information and best practices on improving energy management, energy efficiency, the use of renewable energy by the defence sector as well increasing the protection and resilience of defence energy-related critical energy infrastructures. Building on the achievements of the previous phases (CF SEDSS phase I and II), the European Defence Agency (EDA) with the support of the European Commission (Directorate General Energy -DG ENER and Executive Agency for Small and Medium-sized Enterprises - EASME), looks forward to continuing assisting the MoDs to move towards more affordable, greener, sustainable and secure energy models. In this context, Phase III will contribute in preparing the defence sector to welcome and accommodate new trends in technology and to address challenges ranging from technical and human factors to hybrid threats and other risks. Overall, Phase III is expected to present the defence and security sectors with an economic, operational, and strategic opportunity to reduce reliance on fossil fuel and natural gas, to progressively minimise energy costs and carbon footprint and to enhance the operational effectiveness and energy resilience of their functions.

Keywords: energy,defence,consultation,forum
Hybrid Political Orders and Violent Exchanges in the Eastern Congo (CONGO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-04-01
End date: 2018-03-31
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

Based on anthropological fieldwork in the Eastern Congo, this study investigate ‘hybrid political orders’ e.g. state and non-state groups, such as militias, police, military, local criminal gangs and local authorities such as village chiefs or warlords whose operations transcend the boundaries of what we normally know as state and nonstate and how such actors exercise power through alternative ways of governance and authority. To do so, I apply the concept of ‘violent exchange’ (Jensen 2013). This concept is fruitful in explaining how violence opens up a space in which people are forced to engage with armed networks. In this way, it enables an exploration of bottom-up relations and the how authority yields profits through violent interactions. The study has a strong comparative and interdisciplinary approach as it will contribute to critical inquires that questions the western assumption of state power. The study will be part of a wider research project located at the Danish Institute against torture in Copenhagen, Denmark, where a group of senior researchers are carrying out fieldwork and examining violent exchanges in the Global South. In this way, it will contribute to social science and anthropological theory, to develop the concept of ‘violent exchange’ through fieldwork and bring new empirical data. The results of this study will help to find new methods to monitor violence and to improve human rights work in fragile states.

Keywords: hybrid political orders,violent exchanges,authority,governance