Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Servicing the European Biomedical Research Community: Archiving and Dissemination of Mouse Models of Human Disease (EMMASERVICE)

Framework: FP7 — Capacities
Programme: Research Infrastructures
Destination: Support to existing research infrastructures
Action type: Combination of CP & CSA
Countries involved: Italy,France,United Kingdom,Sweden,Portugal,Germany,Germany,France,United Kingdom,Spain
Call:  (FP7-INFRASTRUCTURES-2008-1, 2008)
Start date: 2009-01-01
End date: 2012-12-31
Duration (months): 48.0
Total project cost (EUR): 10280234.95
EU funding (EUR): 8000000.0
Participants: 10
Project status: CLOSED

The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to: 1) Develop a series of mutant alleles for every gene in the mouse genome 2) Determine the phenotypic consequences of each mutation 3) Identify mouse models for the complete disease spectrum in humans To exploit this emerging resource, mouse models must be preserved and made available to the European biomedical research community. Building on EMMA's previous achievements as the primary mouse repository in Europe, EMMAservice aims to meet the future challenges presented by archiving and disseminating mouse models in the ERA as follows: - Archiving of 1224 new mouse mutant lines in support of individual depositors and also European mouse genetics programmes - Support of eligible customers with free of charge Transnational Access for up to 20% of requested mouse resources. - Technology development will underpin the archiving and distribution efforts by advancing current sperm freezing technology - Training courses will promote the shipment of frozen germplasm rather than live mice - EMMA informatics will support user services by setting new standards for user friendly accession of EMMA services, extensive data curation and cross referencing with other mouse database resources - Outreach efforts to attract users will be widened and addressed at the translational research community EMMAservice will contribute significantly to the development of a world leading repository and European capacity in mouse disease model archiving and distribution, supporting the needs of the wider European biomedical research community. The emerging mouse mutant and associated data resources will offer the opportunity to decipher molecular disease mechanisms and may, in some instances, provide the foundation for the development of diagnostic, prognostic and therapeutic strategies.

Keywords: cryopreservation,functional genomics,mouse mutants,disease models,mouse repository
New feedstock and innovative transformation process for a more sustainable development and production of lignocellulosic ethanol (BABETHANOL)

Framework: FP7 — Cooperation
Programme: Energy
Destination: Renewable fuel production
Action type: Collaborative project
Countries involved: France,Mexico,Costa Rica,Spain,Finland,Italy,France,France
Call:  (FP7-ENERGY-2008-1, 2008)
Start date: 2009-05-01
End date: 2013-04-30
Duration (months): 48.0
Total project cost (EUR): 4389841.4
EU funding (EUR): 3169673.0
Participants: 13
Project status: CLOSED

Today, USA and Brazil have massively invested in ethanol mono-production, taking advantage of their respective native crops, intensive culture practices and large availability of land. These renewable biofuel production models cannot be applied to most of the industrial and emerging countries. For these countries with limited land use, one of the best solutions to comply with their objectives of renewable biofuel and avoid food/fuel competition is the production of ethanol from diversified lignocellulosic residues. Yet, more research efforts are necessary to reach this objective. The BABETHANOL project proposes solutions for a more sustainable approach of 2nd generation renewable ethanol, based on a “moderate, environmental-friendly and integrated” transformation process that should be applicable to an expanded range of lignocellulosic feedstocks. The new process, called CES - Combined Extrusion-Saccharification, will be an alternative to the costly processes of the current state-of-the-art, notably the pre-treatment requiring much energy, water, chemical products, detoxification and waste water treatment. CES will be developed and tested from laboratory up to semi-industrial pilot scale with different new feedstock: Blue Agave Bagass, Palm Oil Empty Fruit Bunches and Olive oil Milled Husks. A Europe-Latin America lignocellullosic biomass catalogue will also be developed as a further contribution to the expansion of feedstocks. The success of the new project much relies on the well-balanced consortium with 7 European partners, 8 Latin American partners, the multidisciplinary expertise with agriculture/agronomy, chemical/catalysis, microbial systems engineering, industrial plant design and the integration of SMEs.

Keywords: lignocellulosic feedstock ethanol process sustainability
Materials for high energy accumulators in traction and tools (MAHEATT)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: Norway,Switzerland,Germany,Germany,France
Call:  (FP7-ENERGY-NMP-2008-1, 2008)
Start date: 2009-04-01
End date: 2012-03-31
Duration (months): 36.0
Total project cost (EUR): 3430063.0
EU funding (EUR): 2545732.0
Participants: 8
Project status: CLOSED

A.1.2. Project summary The overall objective of the MAHEATT project is to develop a prototype cost-effective lithium-ion high energy battery technology with electrode performances well beyond the current state-of-the-art, with automotive applications (hybrid vehicles and electric traction) and hand held tools as application target areas. This will be achieved by innovative synthesis and design of radically improved cathode materials and by optimizing kinetics and stability through nanostructuring of all electroactive materials (EAMs) and components. Main objectives are: • To design synthesis routes and novel electroactive materials for the cathode and for the anode with a much higher specific capacity compared to present EAMs; • To design the EAMs in nanoscopic form to provide a faster kinetics; • To coat the EAMs by a porous conductive layer to suppress undesired (electro-)catalysis and to enhance electronic conductivity; • To optimize binding and assembly of the EAMs into a nanoporous network forming an excellent percolation system for Li-ions and for the electrolyte. The approach is highly cross-disciplinary, with partnership of leading research institutions and leading European industry. The solution to the materials challenges will benefit from integrated feedback between advanced characterization, theory, modelling, synthesis and up-scaling. The key objective for our target materials and systems in relation to electric traction in the automotive sector is a battery that utilizes at least 1.5 times (i.e. 240 mAh/g) larger charge density than current state-of-the art cathode materials.

Keywords: high energy fast li-batteries radically new cathode nanomaterials and coatings optimized anode materials electric traction hand-held tools
Intermolecular Coulombic decay and control of photoinduced processes in physics, chemistry, and biology (ICD)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Physical and Analytical Chemical sciences
Countries involved: Germany
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-02-01
End date: 2015-01-31
Duration (months): 72.0
Total project cost (EUR): 1950000.0
EU funding (EUR): 1950000.0
Participants: 1
Project status: CLOSED

When embedded in a suitable environment, excited or ionized atoms and molecules can hand over their excess energy to their neighbors extremely efficiently via the interatomic (intermolecular) Coulombic decay (ICD) mechanisms. The ICD has been predicted theoretically by the applicant and co-workers and has recently found full confirmation in a series of spectacular experiments. The theoretical and experimental work on ICD performed until now and the progress achieved established the generality of the phenomenon and open new horizons for the ICD research. There is an enormous potential inherent in the ICD and the present proposal is aimed at exploring and exploiting it in systems of physical, chemical, and biological interest. In particular, the high efficiency of the ICD compared to various photoinduced processes like photon emission, isomerization, and charge transfer, makes the ICD extremely attractive for quenching in a controllable fashion such fundamental processes in biophysically relevant systems. Furthermore, the ICD phenomenon produces low-energy electrons and can be expected to be a relevant source of such electrons in nature. It has been proven that low-energy electrons induce serious damages in DNA and it is natural to investigate the importance of the ICD in the production of such electrons after irradiation. We are convinced of the fundamental and practical relevance of ICD and our vision is to be able to exploit this basic process in systems of interest. To achieve this breakthrough requires an enormous investment in advancing methodologies. This, in turn, can only be reached by a highly motivated strong team of scientists closely collaborating over a long period of time. The support by the ERC can substantially contribute to the realization of this vision.

Keywords: controlled quenching of photoinduced processes,ultrafast environment-mediated processes
Liberating Programming (LIBPR)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Computer science and informatics
Countries involved: Israel
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-01-01
End date: 2013-12-31
Duration (months): 60.0
Total project cost (EUR): 2102958.0
EU funding (EUR): 2102958.0
Participants: 1
Project status: CLOSED

We propose to provide the theoretical, algorithmic and methodological foundations, and build the supporting tools, to bring about a major, paradigmatic, revolutionary change in the way software and systems are programmed and executed, based on the idea of liberated programming, a sweeping extension of the scenario-based play-in/play-out approach to program design and execution that I and my group have done around the language of live sequence charts (LSCs). Play-in is a new way of software programming, combining the ideas of showing and teaching, instead of telling, relying on friendly advanced user interfaces, and using intuitive yet formal and expressive visual languages. Play-out is a general name for the technologies of executing played-in programs using powerful tools such as model-checking and synthesis. Our proposed work is divided into four main threads: (1) play-in, the development of new languages and interaction techniques; (2) play-out, the development of new execution technologies; (3) domain specific adaptations and applications; and (4) integration and tools. The play-in techniques proposed include the translation of systems requirements given in natural language into an executable artifact, the use of novel and dynamic human machine interaction techniques, relying on visual languages as target languages. The play-out execution methods proposed include the use of model-checking and synthesis algorithms, compilation, and execution environments that learn. Domain specific applications proposed include web services, tactical simulators, embedded systems, and biological modeling. Finally, we propose to build prototype tools that will allow the evaluation of the new technologies and their dissemination into the academic community and industry.

Keywords: programming,visual formalisms,design and development,software engineering
Hydrothermal and Ionothermal Chemistry For Sustainable Materials (HYDRA-CHEM) (HYDRA-CHEM)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Materials and Synthesis
Countries involved: Germany
Call:  (ERC-2008-AdG, 2008)
Start date: 2008-11-01
End date: 2014-06-30
Duration (months): 68.0
Total project cost (EUR): 2461600.0
EU funding (EUR): 2461600.0
Participants: 1
Project status: CLOSED

This proposal aims to develop a novel type of chemistry by using hydrothermal or ionothermal reaction conditions to generate novel materials and polymers in a more sustainable fashion. Hydrothermal and ionothermal carbonization of sugars or crude biomass can lead directly to large scale carbon materials (and therefore to carbon-negative products and measures), and improvement by processing and hybridization with petrochemistry is expected to yield carbon structures with controlled surface chemistry and nano-morphology and therefore an extended application spectrum, useful for transfer to society. Model experiments indicate that using other simply available substances as monomers under HYDRA-conditions can result in high performance engineering plastics, ultrahigh surface materials for gas-storage, or novel fragments which are otherwise non accessible in comparable qualities under similarly sustainable conditions. That way, it is expected that HYDRA-Chem can expand synthetic chemistry in the direction of high temperatures and rather unusual solvent conditions.

Keywords: hydrothermal synthesis,ionothermal synthesis,carbonization,green chemistry
Quantum Correlations (QORE)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Fundamental constituents of matter
Countries involved: Switzerland
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-01-01
End date: 2013-12-31
Duration (months): 60.0
Total project cost (EUR): 2049600.0
EU funding (EUR): 2049600.0
Participants: 1
Project status: CLOSED

In all sciences one observes correlations and develops and tests theoretical models describing them. Quantum correlations are produced by measurements on entangled quantum states. Since they may violate some Bell inequality even when the different parties are space-like separated, they can t be described with the usual tools: common causes and communication. Violation of a Bell inequality is the signature of quantumness: all other entanglement witnesses depend on assumptions about the dimension of the relevant Hilbert spaces. The vision of this project is that nonlocal quantum correlations provide new resources without any equivalence in other sciences. The core objectives are to better understand, manipulate and exploit nonlocal quantum correlations. This project covers aspects in theoretical, experimental and applied physics, with an emphasis on fundamental questions. The goal is to improve our understanding of quantum nonlocality as a resource (different from entanglement) and to improve our ability to harness entanglement over long distances, both for intellectual and applied motivations. The tools are the conceptual nonlocal box borrowed from theoretical computer science, quantum optics at telecom wavelengths and rare-earth ion doped crystals as atomic ensemble based quantum memories. The expected outcomes are findings about the minimal resources required to simulate quantum correlations and decisive steps towards a Word Wide Quantum Web.

Keywords: quantum communication,quantum cryptography
Detailed chemical kinetic models for cleaner internal combustion engines (CLEAN-ICE)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Products and process engineering
Countries involved: France
Call:  (ERC-2008-AdG, 2008)
Start date: 2008-12-01
End date: 2013-11-30
Duration (months): 60.0
Total project cost (EUR): 1869450.0
EU funding (EUR): 1869450.0
Participants: 1
Project status: CLOSED

The key objective of this project is to promote cleaner and more efficient combustion technologies through the development of theoretically grounded and more accurate chemical models. This is motivated by the fact that the current models which have been developed for the combustion of constituents of gasoline, kerosene, and diesel fuels do a reasonable job in predicting auto-ignition and flame propagation parameters, and the formation of the main regulated pollutants. However their success rate deteriorates sharply in the prediction of the formation of minor products (alkenes, dienes, aromatics, aldehydes) and soot nano-particles, which have a deleterious impact on both the environment and on human health. At the same time, despite an increasing emphasis in shifting from hydrocarbon fossil fuels to bio-fuels (particularly bioethanol and biodiesel), there is a great lack of chemical models for the combustion of oxygenated reactants. The main scientific focus will then be to enlarge and deepen the understanding of the reaction mechanisms and pathways associated with the combustion of an increased range of fuels (hydrocarbons and oxygenated compounds) and to elucidate the formation of a large number of hazardous minor pollutants. The core of the project is to describe at a fundamental level more accurately the reactive chemistry of minor pollutants within extensively validated detailed mechanisms for not only traditional fuels, but also innovative surrogates, describing the complex chemistry of new environmentally important bio-fuels. At the level of individual reactions rate constants, generalized rate constant classes and molecular data will be enhanced by using techniques based on quantum mechanics and on statistical mechanics. Experimental data for validation will be obtained in well defined laboratory reactors by using analytical methods of increased accuracy.

Keywords: combustion,engines,emission of pollutants,biofuels
Quantum Gauge Theories and Ultracold Atoms (QUAGATUA)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Fundamental constituents of matter
Countries involved: Spain
Call:  (ERC-2008-AdG, 2008)
Start date: 2008-11-01
End date: 2013-12-31
Duration (months): 62.0
Total project cost (EUR): 1400000.0
EU funding (EUR): 1400000.0
Participants: 1
Project status: CLOSED

This is an interdisciplinary proposal which concerns physics of ultracold atoms and quantum information on one side, and high energy and condensed matter physics on the other. The main objectives are: i) to identify experimentally feasible ultracold atom systems that may serve as quantum simulators of, or exhibit physics relevant for some challenging high energy systems and/or quantum gauge theories; ii) to study these ultracold atom systems, their properties and possibilities of control them for applications in quantum information and quantum metrology that go beyond the high energy physics and quantum simulations; iii) to make very concrete experimental proposals of preparation, manipulation and detection of such systems. In particular, it is planned to investigate: A) ultracold atoms in artificial non-Abelian gauge fields, and non-Abelian integer and fractional Hall effects; B) ultracold atoms with Dirac like dispersion relations (as in relativistic field theories and/or graphene in condensed matter); C) ultracold atoms in polymerized geometries, i.e. in lattices of weakly coupled groups of neighbouring sites (plaquettes); D) ultracold gases in frustrated geometries that can mimic quantum spin liquids, that in turn are often described by Abelian discrete gauge theories; E) ultracold gases with 3- or 4-atom interactions that can serve as simulators of Abelian lattice gauge theories; F) the ultimate, but rather risky and speculative objective would be to find the possibilities of realizing quantum simulators of non-Abelian gauge theories, i.e. to identify the dynamical degrees of freedom of "gluons" and to distinguish them from that of matter fields. Expected results are: i) concrete proposals to simulate quantum gauge theories;, ii) better understanding of quantum gauge theories with ultracold atoms, iii) discovery of novel types of quantum gauge field systems; iv) novel systems for robust quantum information processing and metrology.

Keywords: ultracold atomic gases,bose-einstein condensation,fermi superliquids,quantum gauge fields,strongly correlated systems
Functionalisation of Diluted Magnetic Semiconductors (FUNDMS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Condensed matter physics
Countries involved: Poland,Austria,Denmark
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-01-01
End date: 2013-12-31
Duration (months): 60.0
Total project cost (EUR): 2440000.0
EU funding (EUR): 2440000.0
Participants: 4
Project status: CLOSED

Low-temperature studies of transition metal doped III-V and II-VI compounds carried out over the last decade have demonstrated the unprecedented opportunity offered by these systems for exploring physical phenomena and device concepts in previously unavailable combinations of quantum structures and ferromagnetism in semiconductors. The work proposed here aims at combining and at advancing epitaxial methods, spatially-resolved nano-characterisation tools, and theoretical modelling in order to understand the intricate interplay between carrier localisation, magnetism, and magnetic ion distribution in DMS, and to develop functional DMS structures. To accomplish these goals we will take advantage of two recent breakthroughs in materials engineering. First, the attainment of high-k oxides makes now possible to generate interfacial hole densities up to 10^21 cm-3. We will exploit gated thin layers of DMS phosphides, nitrides, and oxides, in which hole delocalization and thus high temperature ferromagnetism is to be expected under gate bias. Furthermore we will systematically investigate how the Curie temperature of (Ga,Mn)As can be risen above 180 K. Second, the progress in nanoscale chemical analysis has allowed demonstrating that high temperature ferromagnetism of semiconductors results from nanoscale crystallographic or chemical phase separations into regions containing a large concentration of the magnetic constituent. We will elaborate experimentally and theoretically epitaxy and co-doping protocols for controlling the self-organised growth of magnetic nanostructures, utilizing broadly synchrotron radiation and nanoscopic characterisation tools. The established methods will allow us to obtain on demand either magnetic nano-dots or magnetic nano-columns embedded in a semiconductor host, for which we predict, and will demonstrate, ground-breaking functionalities. We will also assess reports on the possibility of high-temperature ferromagnetism without magnetic ions.

Keywords: magnetically doped phosphides,nitrides,oxides,magneto-optical and magneto-resistive device structures,materials design