Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
European Researchers' Night in Bosnia and Herzegovina 2020 (RiNG-20)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Bosnia and Herzegovina
Call: European Researchers' Night (H2020-MSCA-NIGHT-2020, 2020)
Start date: 2020-07-01
End date: 2021-02-28
Duration (months): 8.0
Total project cost (EUR): 129000.0
EU funding (EUR): 106600.0
Participants: 3
Project status: CLOSED

The European Researchers' Night in Bosnia and Herzegovina 2020 (RiNG-20) aim is to bring researchers closer to the general public and to shape deeper connection between research, creativity and entrepreneurship. RiNG-20 will be a flagship science promotion event in BiH while continuing to work on increasing awareness of research and innovation potentials in BiH, supporting public recognition of researchers and promoting achievements by local scientists and research-driven entrepreneurs, addressing research impact on people’s daily life, and encouraging young people to embark on research careers. Shortly, main objectives are: Enhance researchers’ public recognition; Increase awareness about research results, especially regarding the daily lives of citizens; Stimulate interest in research careers, in particular amongst young people facing a career choice. RiNG-20 slogan is “Discover Hidden Treasures”, dedicating 2020 edition to specifically highlight “hidden treasures” of Bosnia and Herzegovina – while focusing as much on natural as well intellectual resources of this country. RiNG-20 is a multidisciplinary STEAM event, aiming to highlight people in Science, Technology, Entrepreneurship, Arts and Makers in BiH and Western Balkan region. RiNG-20 is a science festival of national character, involving coordinated actions in at least ten cities in Bosnia and Herzegovina, and incorporates cross-border aspect by involving researchers and research-driven business from the Balkan region as participants in RiNG activities. RiNG-20 is aiming to reach over 1 million people during awareness raising campaign and involve at least 20.000 participants in the organized events during 2020 by implementing European Researchers’ Night in ten cities of BiH.

Keywords: european researchers night,science communication,edutainment,public recognition of researchers,promotion of science careers,science festival
Design of Hyper Tall Onshore Wind Turbine Towers (HYPER TOWER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-01
End date: 2019-08-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

HYPER TOWER is a very promising project that will lead to a radical increase in the wind turbine tower height and consequently to an increase in the energy potential harvested by wind structures. The project reaches its aims of constructing taller, more robust and economical towers by realizing 6 work packages that are formulated and developed in 2 years. In approaching the "20-20-20" targets, more and more energy has to come from sustainable energy sources and since "The taller the wind tower is, the greener the energy is", a constant trend of taller wind energy structures is observed. The civil engineers' challenge of constructing taller structures, with heavier machinery hanging at greater heights has led to the need of evolution of a new tower configuration that can reassure the structure's robustness along with a feasible construction schedule. Hyper Tower proposes the elaboration of a new-age tower cross-section and construction methodology, which are elaborated within the project's work packages. Assessment of existing tower configuration is performed, the proposal of a new-age tower section is elaborated, numerical and experimental results are assessed and compared to traditional tower configuration results and the final tower configuration is formulated.

Keywords: structural engineering,civil engineering,wind energy structures,wind turbine tower design,sustainable energy production,economical design
Morphogenetically active blood vessels: Proof-of-Concept (MorphoVES-PoC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-04-01
End date: 2016-09-30
Duration (months): 18.0
Total project cost (EUR): 149962.0
EU funding (EUR): 149962.0
Participants: 1
Project status: CLOSED

Cardiovascular diseases are the leading causes of mortality in Europe and worldwide. Currently, synthetic prostheses used in bypass vascular surgery are produced from polyethylene terephthalate [PET] and expanded polytetrafluoroethylene [ePTFE]. Those materials show less than optimal, insufficient biocompatibility and durability properties, especially if used for SMALL DIAMETER BLOOD VESSELS. Within the frame of ERC Advanced Grant “BIOSILICA” (From gene to biomineral: Biosynthesis and application of sponge biosilica; Grant No. 268476), we unexpectedly discovered that distinct natural, biodegradable and biofunctional polymers, including biosilica and inorganic polyphosphate (anionic), are not only bio-printable but also morphogenetically active. Likewise attractive is that those biopolymers can be functionally processed by non-toxic and charged (cationic) linkers with growth/differentiation potencies. Therefore, these formulations, backbone polymers and bioactive linkers, allowed the fabrication of unprecedented “Modular Small Diameter Vascular Grafts (MSDVGs)" which combine in an optimal way physical strength with physiological activity. Furthermore, the fabrication of the synthetic vessels is performed by a home-made, easy to handle, extruder device which has been developed by our group. Therefore, this new ERC-PoC project will provide small diameter (< 6 mm) blood vessel implants (incl. the fabrication device - the extruder) urgently required in clinics, with superior properties and at low-costs, at the end of the project. We are definitively convinced that, in view of their advantages, our vessels will be preferentially used for patients requiring bypass surgery. The experimental data gathered disclose that we have in hand a product with a clear biomedical application potential. Besides of their economical value, our new type of artificial blood vessel will certainly improve the quality of life and well-being of patients with cardiovascular disorders.

Keywords: cardiovascular diseases,atherosclerosis,prosthetic vascular grafts,biosilica,polyphosphate,small diameter blood vessels,extruder,morphogenetically active polymers
A New Intervention for Implementation of Pharmacogenetics in Psychiatry (PSY-PGx)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Israel,Spain,Switzerland,Belgium,Serbia,Finland,Romania,Sweden,United States,Netherlands,Netherlands,Netherlands,United Kingdom
Call: New interventions for Non-Communicable Diseases (H2020-SC1-2020-Two-Stage-RTD, 2020)
Start date: 2021-03-01
End date: 2026-02-28
Duration (months): 60.0
Total project cost (EUR): 7999611.75
EU funding (EUR): 7999611.75
Participants: 18
Project status: SIGNED

Due to the chronic relapsing nature of mental disorders and increased life expectancy, the societal burden of these non-communicable diseases will increase even further. Treatments for mental disorders are available, but their effect is limited due to patients’ (genetic) heterogeneity, low treatment compliance and frequent side effects. Only one-third of the patients respond to treatment. Today, medication selection in psychiatry relies on a trial-and-error approach based mainly on physicians’ experience. Pharmacogenetic testing enables assessing person-specific genetic factors that predict clinical response and side effects. Recent studies show that genotyping of drug-metabolizing enzymes can increase the effectiveness of treatment, which could benefit millions of patients. PSY-PGx is the first initiative to propose a large-scale non-industry sponsored clinical study that demonstrates the clinical benefits and potential of implementing pharmacogenetics for psychiatric patients in existing medical settings. To this end 1) available biobank data (www.biobankki.fi, www.ukbiobank.ac.uk), with the aid of AI, will be searched for pharmacogenetics that influence medication response. This information is used to 2) perform a clinical trial that will be the first large international, multicenter clinical trial on using pharmacogenetic-based treatment personalization in real-life psychiatric care for depressed, anxiety or psychotic disorder patients. All data is combined with AI to set-up an algorithm for personalizing medication prescription for psychiatric patients that reduces side effects and increases effectiveness of pharmacotherapy. PSY-PGx will thus deliver a new model of care for sustainable healthcare systems and reduce the suffering of psychiatric patients.

Keywords: psychiatry,pharmacogenetics,individualised pharmacotherapy,psychofarmaca
A Cardiomyocyte Workout: Using Dielectric Elastomer Actuators for Mechanical Stimulation of in-vitro Cells (CellStretch)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Switzerland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 187419.6
EU funding (EUR): 187419.6
Participants: 1
Project status: CLOSED

The CellStretch project will tackle fundamental questions regarding cardiac arrhythmia mechanisms by leveraging cutting-edge Dielectric Elastomer Actuator (DEA) technology. The development and implementation of a dynamic cell stretching platform using transparent, bio-compatible DEAs is proposed. Novel manufacturing methods of the platform, including the integration of highly stretchable and compliant electrodes, enable the precise control of an applied strain. Attached cells can thereby be mechanically modulated at a well-defined level and rate of stimulation. As the proposed device is transparent, the impact on the cells can be observed using standard optical microscopy protocols in real time. Typically, physiological studies on the cellular and tissue levels are performed in vitro with full control of the experimental environment. A rigid petri dish however, precludes addressing the mechanical degree of freedom. DEAs can transform the static environment of current in-vitro experiments into a dynamically strain-controlled setup. This is not only ideally suited to study the mechanosensitive response of cells, but is also a closer in-vitro approximation to the cells native in-vivo biological environment. The cell stretcher will be used to conduct experiments of mechanical perturbations on cardiomyocytes. Measurements will focus on the impulse propagation velocity and voltage-sensitive die imaging of cell cultures, as a function of externally applied mechanical strain. Such experiments are currently hampered by inadequate apparatus, lacking in speed, flexibility and throughput. The cell stretchers developed promise to enable a host of new experiments on living cells. Studies on cardiomyocytes will demonstrate the strengths of this technology and will be sued to tackle fundamental physiological questions related to arrhythmia mechanisms. In the long term, this can lead to improved treatment for cardiovascular disease, the number one cause of death in the EU.

Keywords: electromechanically active polymer,dielectric elastomer actuator,cardiomyocytes,cell stretcher,mechanical strain,impulse propagation velocity,patch clamp
Boosting Investment Readiness of SMEs and Small Midcaps - InvestHorizon (InvestHorizon)

Framework: Horizon 2020 — Industrial Leadership
Programme: Access to risk finance
Action type: Coordination and support actions
Countries involved: Spain,Italy,Spain,Ireland,Germany,Serbia,Belgium,Belgium,Finland,Bulgaria,Latvia,France,France,France,Czechia,Netherlands,Netherlands,Netherlands,United Kingdom
Call: Boosting the Investment-Readiness of SMEs and Small Midcaps (H2020-BIR-2014, 2014)
Start date: 2014-12-01
End date: 2017-05-31
Duration (months): 30.0
Total project cost (EUR): 2319201.25
EU funding (EUR): 2319201.25
Participants: 24
Project status: CLOSED

InvestHorizon will address the main challenges affecting investment readiness: - the lack of programmes addressing investment readiness across Europe; - the low awareness regarding investment readiness and financing options amongst entrepreneurs; - the weak interest of different investor types for innovative SMEs across the technology sectors; - the weak investability of many of the companies and presentational failings, and; - the difficulty of matching innovative companies with specialized investors. InvestHorizon will pursue the following 5 objectives: 1) Identify, recommend and communicate those strategies, indicators, schemes and tools with the best impact on investment readiness and investors sensitization and matching; 2) Raise the awareness amongst innovative SMEs across origination types, stages, countries, technology sectors about those key topics affecting their knowledge and capacity to improve their investment readiness; 3) Increase the interest of investors across the range of technology sectors and across the range of different types of (co)-investors; 4) Improve the investment readiness of 3000 SMEs by boosting their business and investor propositions as well as their presentation pitch, and; 5) Matching at least 450+ investment ready companies with specialized investors across Europe. The Consortium is composed of 10 partners each with relevant pan-European networks covering public research tech transfer (ASTP-Proton, IULG, UVT), accelerators and incubators (F6S, EBN and BWCON), the SME and Chambers of Commerce (Eurochambres) and the range of investor types (EBAN, European Crowdfunding Network and Europe Unlimited also representing Tech Tour and the International Venture Club). We anticipate that at least 50 companies will be receiving funding for a total amount of minimally EUR 25 million. Furthermore, the tools and knowledge developed by the Consortium will be sustained at least across its Membership networks.

Keywords: investment readiness,training,coaching,mentoring,pitching,e pitching,funding,crowdfunding
Admixture accelerated adaptation: signals from modern, ancient and archaic DNA. (ARCHAIC ADAPT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Ireland
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2020-12-01
End date: 2025-11-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

With the advent of new sequencing technologies, population geneticists now have access to more data than ever before. We have access to thousands of human genomes from a diverse set of populations around the globe, and, thanks to advances in DNA extraction and library preparation, we now are beginning to have access to ancient DNA sequence data. These data have greatly improved our knowledge of human history, human adaptation to different environments and human disease. Genome-wide studies have highlighted many genes or genomic loci that may play a role in adaptive or disease related phenotypes of biological importance. With these collections of modern and ancient sequence data we want to answer a key evolutionary question: how do human adaptations arise? We strongly believe that the state-of-the-art methodologies for uncovering signatures of adaptation are blind to potential modes of adaptation because they are lacking two critical components – more complete integration of multiple population haplotype data (including archaic, ancient and modern samples), and an account of population interactions that facilitate adaptation. Therefore I plan to develop new methods to detect shared selective events across populations by creating novel statistical summaries, and to detect admixture-facilitated adaptation which we believe is likely a common mode of natural selection. We will apply these tools to new datasets to characterize the interplay of natural selection, archaic and modern admixture in populations in the Americas and make a comparative analysis of modern and ancient European samples to understand the origin and changing profile of adaptive archaic alleles. As a result our work will reveal evolutionary processes that have played an important role in human evolution and disease.
Exploiting the synergies between Gaia and spectroscopic stellar surveys to constrain next-generation Milky-Way models (GaiaSpectroSynergy)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-02-01
End date: 2021-01-31
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

Galaxies are complex systems governed by competing physical processes that happen on very different space, time and energy scales, such as mergers, internal secular evolution, gas flows, star formation, supernova feedback, gas cooling etc. The field of Galactic archaeology aims at disentangling these processes, eventually unfolding the detailed formation history of the our Galaxy. Major observational campaigns, such as the astrometric Gaia mission, the asteroseismology missions CoRoT and Kepler, as well as large-scale ground-based spectroscopic surveys, are dedicated to gather kinematic, chemical, and age information for millions of stars. The wealth of new data has recently put the goal of reconstructing the Milky Way's formation history within closer reach. While the Galactic astronomy community is convinced that combining as many observational constraints for as many stars as possible will be the way forward in the field, it is clear that the complexity and richness of the new data is also a major challenge to our state-of-the-art analysis methods. At this moment, the field is in urgent need of more sophisticated comparisons to current models, and clear indications where these models should be improved. However, there is still a lack of publically available software that facilitates complex model-data comparisons for the theoretical as well as for the observational community. We will undertake a major analysis project exploiting the synergies between Gaia and complementary spectroscopic survey data to constrain Galactic models, and to simultaneously provide the community with legacy tools and datasets that will greatly facilitate such studies in the future. The project will produce value-added catalogues with precise astro-spectro-photometric ages, distances and extinctions for more than a million stars, and corresponding mock catalogues of many state-of-the-art Milky-Way models, providing a legacy database for future modeling and analysis efforts.

Keywords: galactic evolution,spectroscopic stellar surveys,galaxy formation,astrometry,milky way models,asteroseismology,red giant stars,stellar ages,mock observation tools
3D micro-supercapacitors for embedded electronics (3D-CAP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: France
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-04-01
End date: 2023-09-30
Duration (months): 66.0
Total project cost (EUR): 1673438.0
EU funding (EUR): 1673438.0
Participants: 1
Project status: SIGNED

The realization of high-performance micro-supercapacitors is currently a big challenge but the ineluctable applications requiring such miniaturized energy storage devices are continuously emerging, from wearable electronic gadgets to wireless sensor networks. Although they store less energy than micro-batteries, micro-supercapacitors can be charged and discharged very rapidly and exhibit a quasi-unlimited lifetime. The global scientific research is consequently largely focused on the improvement of their capacitance and energetic performances. However, to date, they are still far from being able to power sensors or electronic components. Here I propose a 3D paradigm shift of micro-supercapacitor design to ensure increased energy storage capacities. Hydrous ruthenium dioxide (RuO2) is a pseudocapacitive material for supercapacitor electrode well-known for its high capacitance. A thin-film of ruthenium will be deposited by atomic layer deposition (ALD), followed by an electrochemical oxidation process, onto a high-surface-area 3D current collector prepared via an ingenious dynamic template built with hydrogen bubbles. The structural features of these 3D architectures will be controllably tailored by the processing methodologies. These electrodes will be combined with an innovative electrolyte in solid form (a protic ionogel) able to operate over an extended cell voltage. In a parallel investigation, we will develop a fundamental understanding of electrochemical reactions occurring at the nanoscale with a FIB-patterned (Focused Ion Beam) RuO2 nano-supercapacitor. The resulting 3D micro-supercapacitors should display extremely high power, long lifetime and – for the first time – energy densities competing or even exceeding that of micro-batteries. As a key achievement, prototypes will be designed using a new concept based on a self-adaptative micro-supercapacitors matrix, which arranges itself according to the global amount of energy stored.

Keywords: electrical energy storage,micro supercapacitor,three dimensional electrode,autonomous self powered systems