Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
HIgh Stability VErtical SeparaTion Altimeter instruments (HISVESTA)

Framework: FP7 — Cooperation
Programme: Transport (including Aeronautics)
Destination: Aeronautics and air transport
Action type: Collaborative project
Countries involved: Norway,Romania,United Kingdom,Romania
Call:  (FP7-AAT-2007-RTD-1, 2007)
Start date: 2009-01-01
End date: 2011-06-30
Duration (months): 30.0
Total project cost (EUR): 3136667.0
EU funding (EUR): 2208250.0
Participants: 5
Project status: CLOSED

The strategic objective of the project is to increase the safety in all in-flight situations, particularly low visibility situations, by improving the altimetry transducers used in Air Data Computers for aircraft applications. The project is relevant in auto pilot situations in the reduced vertical separation minima legislation of 1000ft, as well as in demanding manual flying situations such as darkness and low visibility. Used in enhanced transponder applications, the project will contribute to significantly increased reliability in altitude information for manual and automated Air Traffic Control systems. Aircraft Traffic Collision Avoidance Systems will also benefit from more accurate and reliable altitude information, which will allow the automated avoidance instructions to be more accurate and effective. HISVESTA is the next step in solving the remaining RTD challenges after the successful HASTAC project in FP6. The project will develop a new generation of altimetry module, suitable for fixed wing and rotary wing applications, which will give altitude accuracy capabilities significantly improved over those currently available today. Air Data Computer and aircraft flight testing performed in the project will demonstrate the effectiveness of the performance improvement. A key HISVESTA target is for the European avionic system industry to regain the market lead in altimetry and automatic ATC solutions as well as in altitude pressure transducers with best in class long-term stability. Another project objective is to contribute to reduction of the emission of CO2 and NOx significantly in the next generation jet Engines, by improving the multifunctional pressure control system in the Full Authority Digital Engine Control systems. This initiative consists of a strong consortium of European SMEs and participants from new member states. The entities in the Consortium have worked together successfully in the past; enhancing the probability for success.

Keywords: altimeter transducer,engine control,air data computer,mems pressure sensor
Novel biofunctional high porous polymer scaffolds and techniques controlling angiogenesis for the regeneration and repair of the degenerated intervertebral disc. (DISC REGENERATION)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: Italy,Switzerland,United Kingdom,Portugal,Spain,Sweden,Ireland,Germany,Spain,Romania,United Kingdom,Portugal,Belgium,Germany
Call:  (FP7-NMP-2007-LARGE-1, 2007)
Start date: 2008-11-01
End date: 2012-10-31
Duration (months): 48.0
Total project cost (EUR): 9422854.0
EU funding (EUR): 6977150.0
Participants: 17
Project status: CLOSED

30% of European workers experience back pain, and it is the most frequently reported work-related disorder. The proposed work seeks to provide a cure for lower back pain by developing porous scaffolds and technology which will repair a damaged intervertebral disc (IVD) by enabling its regeneration to a natural healthy state or better. Injectable acellular and cell-loaded bioactive polymer-based scaffolds will be developed. These will be designed to be implanted into the patient by minimally invasive surgery. A biomimetic approach will confer the appropriate mechanical and biological properties and enable the inclusion of the requisite cell signalling factors to produce a bio-hybrid structure which closely resembles the human tissue in all its essential attributes. Particular attention will be paid to angiogenesis. In IVD tissue, vascularization must be carefully controlled, due to the unique anatomy and physiology of the intervertebral disc. There must be negligible vascularization in the annulus and nucleus regions and moderate vascularization at the vertebral body level. Work will therefore be performed on materials functionalization, and on growth factor incorporation and delivery, to enable this region-specific control of vascularization at different levels. Natural IVD tissue contains a relatively low number of cells, which are chondrocyte-like in character. Consequently, it will be necessary to devote some research to identifying and evaluating suitable and more readily available alternative cells for incorporation in the bio-hybrid substitutes produced . Modelling studies will identify the physical and mechanical properties of the natural IVD and the substitute materials, and provide an understanding of the physical aspects of the regeneration process. In vivo study on animal model will be performed the bio-fuctionality of both sustitutes. Surgical methodology and protocol will be developed.

Keywords: scaffolds,intervertebral disc,angiogenesis,tissue engineering,biomaterials,modelling,growth factors,back pain.
Pathogenomics and Systems Biology of Fungal Infections – An Integrative Approach (FINSYSB)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,France,Germany,Germany,Netherlands,Italy,Netherlands,Germany,Israel,Germany,United Kingdom
Call:  (FP7-PEOPLE-2007-1-1-ITN, 2007)
Start date: 2008-10-01
End date: 2012-09-30
Duration (months): 48.0
Total project cost (EUR): 3638872.0
EU funding (EUR): 3638872.0
Participants: 12
Project status: CLOSED

The vision of the FINSysB Network is to generate bright, ambitious and well-trained young researchers capable of contributing significantly to the knowledge-base and economy of the European Union. We will achieve this goal by providing a strong, multidisciplinary training for early stage and experienced researchers in the pathobiology, genomics, molecular biology, bioinformatics and systems biology of the medically important fungus, Candida albicans. This microbe causes frequent infections in otherwise healthy individuals and is a common cause of potentially lethal hospital acquired infections in intensive care patients in the EU. Our well-integrated research programme will dissect and model the molecular interactions that take place between this fungal pathogen and its human host during disease progression. FINSysB partners are all internationally renowned, contributing complementary expertise in pathobiology, genomics, molecular biology, bioinformatics and systems biology. Our two SME partners provide a well-defined route for the translation of our research into the development of novel, clinically useful diagnostic tools and antifungal therapies. Our research activities will be supplemented by well-structured training programmes in research skills and complementary transferable skills. This training extends successful programmes that were established during FP6. They will impart state-of-the-art skills in modern predictive and experimental biology as well as useful generic skills. The personal development plans of our young researchers will be enhanced further by secondments to industrial and academic partners and by attendance at advanced summer schools (e.g. on Human Fungal Pathogens, and Yeast Systems Biology). Using this combination of approaches we will provide our early stage and experienced researchers with well-defined career opportunities and equip them with the tools to compete effectively on the international stage.

Keywords: health sciences,infection,systems biology,disseminated candidiasis,antifungal drug targets,diagnostics,vaccines,immune responses,pathogenicity,virulence factors,genetic susceptibility.
Multi-functional Analytical Focussed ion beam tool for nanotechnology (FIBLYS)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Nanosciences and Nanotechnologies
Action type: Collaborative project
Countries involved: Germany,Czechia,Switzerland,Germany,France,Germany
Call:  (FP7-NMP-2007-SME-1, 2007)
Start date: 2008-09-01
End date: 2011-08-31
Duration (months): 36.0
Total project cost (EUR): 4488034.4
EU funding (EUR): 3408262.0
Participants: 9
Project status: CLOSED

The project FIBLYS aims at developing an innovative nanostructuring, nanomanipulation and nanoanalysis instrument: a hybrid scanning probe (SPM) and dual beam focussed ion beam (FIB) instrument (including scanning electron microscopy (SEM) capabilities). In addition to an instrument based on conventional dual beam FIB(SEM) technology, an SPM/FIB(SEM) microscope will use both techniques, integrated in a compact setup offering capabilities that not only combine the techniques but allow for nanoanalysis and nanostructuring/-manipulation options that the single instrument or sequential use of the techniques is unable to achieve. This FIBLYS hybrid device will allow to use all FIB capabilities while imaging the procedures with the integrated SEM. The SEM has the options of chemical analysis through Energy Dispersive X-ray analysis (EDX) and structural analysis through Electron Backscatter diffraction (EBSD). The combination of SEM and SPM provides for the combination of nano-scale chemistry and crystallography imaging via electron-matter interactions (EDX, EBSD) with the information from tip-sample interactions like topography or magnetic/electrostatic force imaging. Combining electron-matter and tip-sample interactions, the FIBLYS hybrid instrument will for the first time allow to probe with nano-scale resolution many electron-matter interactions like detection of electron beam induced current (EBIC), or cathodoluminescence or phonons, or backscattered electrons directly at the surface with cantilever based sensors. This project will merge FIB(SEM) and SPM manufacturers at European level and reinforce their competitiveness. The partnership reflects the excellence and competences needed in this project, only possible through transnational co-operative research of six SMEs (SPM and FI(SEM) manufacturers, specialists in SPM and SEM control, expertise in electron/ion optics, cantilever manufacturers for SPM techniques as well as three RTD performers.

Keywords: nanotechnology,focussed ion beam,sem,nanomanipulation,nanoanalysis,nanostructuring
EUROPRACTICE CAD and IC service for European universities and research institutes (EUROPRACTICE IC4)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Coordination and support actions
Countries involved: Belgium,United Kingdom,Germany
Call:  (FP7-ICT-2007-1, 2007)
Start date: 2008-01-01
End date: 2010-12-31
Duration (months): 36.0
Total project cost (EUR): 4821082.0
EU funding (EUR): 3150000.0
Participants: 3
Project status: CLOSED

This proposal is submitted to continue the current Europractice IC Service. The current EUROPRACTICE IC Service project, part of the 6th Framework and ending on 31 December 2008, is widely recognized as a world-class service offering state-of-the-art CAD tools and technologies to universities and industry. Continuation of this project is considered indispensable as universities need to be able to renew their annual CAD licenses and need continued support for their research and courses and need to be further stimulated to keep up with new technologies. Continuation is needed and in order to avoid a gap (waiting for the next call – possibly only in 2008), this proposal is submitted now. The objectives are offering access to CAD tools for learning and access to advanced IC technologies for prototyping. Under this project 550 European universities and 50 research centers will be able to use the service and will get technical support both on the use and installation of CAD tools and on the ASIC technologies and design kits. As a broker, Europractice negotiates low cost conditions with the most popular industrial-standard CAD vendors for educational use. Europractice has negotiated with several IC foundries agreements to buy or share low cost MPW (Multi Project Wafer) runs in order to offer low cost prototype possibilities to universities and research institutes. New advanced technologies, such as 0.13um SiGe, 0.18um High Voltage, 90nm and 65nm CMOS will be added to the portfolio of offered technologies when those technologies become available and affordable. Also discussions will start with other European “service” providers, initiated by EC funded projects, in order to make them available on wider European scale to the existing network of 550 universities. As such, the IC service will be further extended with prototyping possibilities in selected MEMS-like technologies.

Keywords: cad ic mpw service
Development of a rapid configuration system for textile production machinery based on the physical behaviour simulation of precision textile structures (MODSIMTEX)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: New production
Action type: Collaborative project
Countries involved: Spain,Poland,Germany,Germany,Czechia,Czechia,Italy,Czechia,Belgium,Germany,Germany
Call:  (FP7-NMP-2007-SMALL-1, 2007)
Start date: 2008-11-01
End date: 2012-04-30
Duration (months): 42.0
Total project cost (EUR): 4624494.0
EU funding (EUR): 3299340.0
Participants: 12
Project status: CLOSED

The textile industry faces important challenges regarding the production of new advanced textile products. It is not possible to define the characteristics and parameters of a given textile structure due to the difficulty of measuring them. This situation makes very difficult to configure the machines involved in the production of such textiles; the typical practices consists in manufacturing samples and through trial and error adjust the processing operations until the desired characteristics are achieved in the final product. With this procedure it’s very expensive to match the designer’s idea with the final product. The production setup takes a long amount of time and efforts and increases the cost of the final product. This is especially critical when a company is trying to develop new technical textiles. The vast majority of the existing systems capable to simulate textile products are limited to the visual representation, without any kind of mechanical or physical evaluation of the properties of the textile structures. Of course, these tools don’t take into account the configuration of the production machinery, so they aren’t capable of help in the setup of production machinery. Unlike these conventional design systems, the core of this proposal is to develop a virtual simulation system of the physical-mechanical properties of the textile structures oriented to the fast setup of the machines involved in the whole textile chain manufacturing process (yarns, woven fabrics, knit fabrics, needle-punch non-woven, hydro-tangled non-woven, and composite structures). This virtual construction system will allow the prediction of the multifunctional textile performance before the actual textile is manufactured allowing the settings of the production machines to be either an input or an output of the computation thus reducing dramatically the effort and cost to produce small batches or develop a new advanced technological textile.

Keywords: rapid machine setting,textile,simulation,physical behaviour of fabrics,small batches.
New Molecular Purification Technology for Pharmaceutical Production (NEMOPUR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany,Italy,United Kingdom,Belgium,Switzerland,Sweden,Portugal
Call:  (FP7-PEOPLE-2007-1-1-ITN, 2007)
Start date: 2008-09-01
End date: 2012-08-31
Duration (months): 48.0
Total project cost (EUR): 2937833.0
EU funding (EUR): 2937833.0
Participants: 9
Project status: CLOSED

The NEMOPUR Initial Training Network will focus on creating a new generation of molecular purification technologies for Active Pharmaceutical Ingredient (API) manufacture, with a particular focus on removal of organic impurities from API production. New membranes with improved chemical stability in a wide range of solvents, and better controlled cutoff properties, novel molecularly imprinted polymers with readily scalable production chemistries, and composite molecularly imprinted film – macroporous support membranes will be developed. The applications of these technologies will be through the industrial partners. The project is multidisciplinary, involving chemists, materials scientists and chemical engineers. The consortium is intersectorial, comprising 3 universities/research institutes, 2 technology SMEs and 4 pharmaceutical manufacturers, and will have a strong emphasis on knowledge creation, technology commercialisation, and entrepreneurship. The training programme involves Early Stage Researchers (ESR), at both university and industrial partners, each of whom will complete a PhD thesis through a combination of local and network wide research experience. Experienced Researchers (ER) will complete their training, focussing on knowledge transfer, commercialisation and entreprenuership skills. In addition to their individual research, ESR and ER will complete complementary training through a series of Personal Skills Modules, and a course on Technology Commercialisation and Entrepreurship. NEMOPUR seeks to contribute to improving the European knowledge supply chain through this industry-academia programme of applied research aimed at developing engineers and scientists who are academically excellent and achieve PhD degrees, but who thrive at the interface between fundamental research and industrial application.

Keywords: polymer chemistry,chemical engineering,separation technology,membrane technology,pharmaceutical chemistry,polymer technology,technological sciences
Angiogenesis-inducing Bioactive and Bioresponsive Scaffolds in Tissue Enginering (ANGIOSCAFF)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: Switzerland,Sweden,Spain,Israel,United Kingdom,Germany,Italy,Germany,Spain,Germany,Germany,Austria,Italy,United Kingdom,United Kingdom,Germany,Sweden,United Kingdom,Germany
Call:  (FP7-NMP-2007-LARGE-1, 2007)
Start date: 2008-12-01
End date: 2012-11-30
Duration (months): 48.0
Total project cost (EUR): 15468430.56
EU funding (EUR): 11631240.0
Participants: 33
Project status: CLOSED

Angiogenesis underlies almost all biological processes of morphogenesis, including those in tissue repair and regeneration. Physiological angiogenesis is controlled by a complex interplay between cells and their environment: the extracellular matrix (ECM) provides signaling via numerous ECM adhesion molecules and growth factors bound to ECM polysaccharide components; and cells locally degrade and remodel the ECM to create pores into which angiogenic endothelial cells migrate. This observation, that physiological angiogenesis proceeds in response to solid-phase cues motivates our approach, namely creating bioactive resorbable materials as scaffolds that contain bound molecular signals to induce physiological angiogenesis in situations of tissue repair and regeneration. In some of our scaffold materials, porosity is inherent by virtue of fabrication, and in others porosity is created by cell-associated proteolysis as it is in physiological angiogenesis. All materials will be designed so as to be injectable or implantable into the human body. In some work, the final injectable/implantable material will comprise only materials and bioactive biomolecular signals, and in other cases it will also comprise cells. Thus, the concept of ANGIOSCAFF is to create materials that are bioresponsive (to environmental signals including pH and redox potential, and to cellular signals such as proteases), that are bioactive (by virtue of bound peptide or recombinant protein adhesion ligands and bound and releasable growth factors), and that are capable of carrying cellular therapeutics. To realize ANGIOSCAFF, we have assembled a team comprising both industrial and academic expert groups in biomaterials design and development, experts in the science and application of angiogenesis, in imaging in animal models, and in applications demanding biomaterials-based, angiogenesis-demanding tissue engineering therapies, including repair of bone, skin, cardiac muscle, skeletal muscle and nerve.

Keywords: biomaterial,scaffold,angiogenesis,growth factors,cell transplantation,therapeutics
Development of a flexible and energy-efficient pressurised microwave heating process to produce 3D-shaped renewable bio-polymer foams for a novel generation of transportation packaging (REBIOFOAM)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: Italy,United Kingdom,Germany,Czechia,Spain,Italy,Italy,Netherlands,Ireland,Poland
Call:  (FP7-NMP-2007-SME-1, 2007)
Start date: 2009-02-01
End date: 2013-01-31
Duration (months): 48.0
Total project cost (EUR): 5102653.13
EU funding (EUR): 3499942.0
Participants: 11
Project status: CLOSED

Expanded Polystyrene (EPS), Polyurethane (EPU), Polyethylene (EPE) and Polypropylene (EPP) represent the most popular moulded cushion packaging materials applied for transport packaging applications. However, despite of their functionality, the widespread use of these polymer foams of synthetic origin implies considerable environmental concerns. The depletion of non-renewable fossil raw material resources associated with emissions of greenhouse gases, such as C5H12 and CO2 applied as blowing agents during processing, are the most direct impacts on the environment. Moreover, their non-biodegradable / non-compostable nature associated with the short life of cushion packaging products rises up fundamental concerns regarding waste disposal. Recycling, which is the solely applicable solution for preventing those synthetic foams entering the waste stream, appears in fact to be rarely applied due to cost-ineffectiveness and lack of effective recycling system. With this in mind, bio-based plastics represent an emerging highly promising solution for protective transport packaging provided that they can be processed in foamed products resulting in adequate functional requirements. Within this framework, the project idea is to develop a flexible, energy-efficient and environmentally-sustainable manufacturing process enabling the production of biodegradable foamed 3D-shaped packaging originating from renewable raw materials (i.e. starch and water). Within the proposed process, expansion and foaming of the bio-polymer will be driven by pressurized microwave technology, exploiting the inner water content of the material itself to generate vapour. The proposal is fully compliant with the targeted topic “NMP-2007-2.4-1 Flexible efficient processing for polymers”, as the proposed process offers a valid alternative to petroleum-based polymer processing, involving the use of renewable feedstocks, and involving microwaves as energy-efficient processing solution.

Keywords: polymer processing - foamed biopolymers - transport packaging