Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Fully digital Blockchain-based Laboratory Operations Control System for real-time and audit-proof Good Manufacturing Practice conformity (B-LOCS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Germany,France,Bulgaria
Call: Strategic Digital and Health Technologies (HORIZON-EIC-2021-ACCELERATORCHALLENGES-01, 2021)
Start date: 2022-07-01
End date: 2024-06-30
Duration (months): 24.0
Total project cost (EUR): 2272500.0
EU funding (EUR): 1538250.0
Participants: 3
Project status: SIGNED

B-LOCS aims at monitoring the analyses performed on the laboratory software and at detecting whether the raw data have been altered by anomalies resulting from protocol errors or actions that do not comply with the GMP rules. B-LOCS records in real time the events that occur on the files from the lab software and sends them to a smart contract on a blockchain. In order to properly report the status of the analysis, the business logic of each software (for file creation or invalid action events - e.g. file deletion) is recorded immutably in a Smart-Contract. Any deviation is reported and triggers real time configurable alarms. The strength of this approach lies in the trust provided by the Smart-Contract running on the blockchain: it contains the business logic that decides whether the latest event impacts the validity of a laboratory analysis performed. There is no way to bypass this GMP-relevant business logic; no way to override the B-LOCS and the history of the blockchain.

Keywords: end to end transparency,laboratory digitisation,patient safety,documentation and reporting,good manufacturing processes,immutability,trust,audit proof,gmp compliance,data integrity
Alexandrian Scientific Tradition in Eastern Rome, Europe and Syria (ASTERES)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

ASTERES aims to understand how astronomical knowledge developed in Alexandria from the works of Claudius Ptolemy has been transmitted during the 6th and 7th centuries in Europe and the Mediterranean World. Through an investigation of documents that had never been edited, the project considers the role of Greek as well as Syriac and Latin-speaking scholars in the circulation and reception of Greek scientific knowledge before the flourishing of sciences in Baghdad and the so-called Carolingian Renaissance. The traditional narrative considers Arab-speaking scholars, after the foundation of the Abbasid califate, to be the first heirs to the Alexandrian scholarship, coming up with Greek science only thanks to the mediation of Syriac translations. It is also widely believed that Latin-speaking intellectual circles in Western Europe would not have been familiar with Greek science before the Latin translations of Arabic texts produced from the 11th century onwards. The 6th and 7th centuries in Western Europe and the Byzantine Empire, have thus been traditionally described as “Dark Ages”. The aim of ASTERES is to write a new history of the forms and paths of transmission and study of the Alexandrian sciences, specifically astronomy, in the Early Middle Ages. It will investigate three sets of documents, including numerical tables, produced during this period. Two astronomical and chronological letters with tables of the Syriac scholar Severus Sebokht will be edited for the first time. Their study will help to understand to which extent Syriac scholars received Greek knowledge to create an original scientific production. The edition of the Latin tables of the Preceptum canonis Ptolomei aims at understanding how astronomical tables were transmitted and received in Western Europe before the 11th century. The study of the astronomical tables produced by the Byzantine scholar Stephanos will show how astronomers in Constantinople cultivated their Alexandrian scientific heritage.

Keywords: greek astronomy mediterranean syriac sciences latin astronomy astronomical tables alexandria early middle ages
Unobtrusive Technologies for Secure and Seamless Border Crossing for Travel Facilitation (ODYSSEUS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Border Management
Action type: Innovation actions
Countries involved: Romania,Portugal,Greece,Bulgaria,Slovakia,Moldova, Republic of,France,United Kingdom,Cyprus,Belgium,Czechia,Italy
Call: Improved border checks for travel facilitation across external borders and improved experiences for both passengers and border authorities’ staff (HORIZON-CL3-2021-BM-01, 2021)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 4600089.29
EU funding (EUR): 3457062.5
Participants: 14
Project status: SIGNED

The World Economic Forum suggests that transnational travel will increase by 50% over the next ten years, bringing the number of arrivals to 1.8bn by 2030 before the COVID-19 pandemic. Given the ever-increasing travel both on land and sea, delays and queues are often observed at cases where people are crossing border. These delays create huge frustration for the citizens and at the same time put extra burden to the border authorities’ staff. In Europe, airports have managed to improve to a certain extend the border crossing through the facial recognition booths for European citizens that own an RFID enabled passport, however there are still huge queues observed. For non-European citizens, the situation is even worse. The border control for land and sea are placing all the effort to the border authorities staff requiring from them to check the passports of the travellers as well as to control the luggage and baggage. Reasonably, even without huge number of travellers, large delays and queues are observed. ODYSSEUS will enable citizens to seamlessly cross the border without stopping, while reducing the workload and improving productivity for Border Guard Authorities by providing highly detailed risk analysis. ODYSSEUS will leverage the power of digital technology offering to citizens the appropriate tools to cross land and sea borders in a secure and seamless manner without stopping while equipping the border authorities with novel tools for secure identity verification and unobtrusive vehicle/luggage/cargo checks, eliminating long delays at border areas. The proposed technologies will allow citizens to cross borders without any intervention by just leveraging their smartphones combined with strong and continuous identity verification. Remote vehicle/luggage scanning through X-Rays and UAVs, will allow authorities to remotely perform the appropriate controls.

Keywords: land and sea borders,secure identity verification,unobtrusive vehicle luggage cargo checks,x ray scanners mounted in uavs,identity verification,border crossing with the help of smartphones
Green solvent recycling for sustainable, eco-friendly perovskite photovoltaics (ECOPV)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 1
Project status: TERMINATED

In response to recent climate tragedies, European Union (EU) is taking rapid action with its ambitious European Green Deal (EGD) to transform our economies and societies greener. As a result, the EU is encouraging the transformation of our buildings and vehicles from energy consumers to energy producers by installing lightweight, flexible, transparent, low-cost, high-efficiency solar panels. These are precisely the features of thin-film perovskite photovoltaics (PeroPVs). Drawing insights from tremendous silicon PV waste awaiting treatment, the recycling technologies within a circular economy become a prerequisite prior to the widespread commercial adoption of any PV technology. It is particularly important for perovskite photovoltaics to mitigate lead (Pb) consumption and prevent lead-containing waste release. In recent years, lead recycling was raised to extract lead ions from the end-of-life modules through lead absorbents and subsequently recover lead ions to lead iodide for new module fabrication. However, the low atomic efficiency and involvement of hazardous solvents in current recycling technology diminish the economic benefits and industry compatibility. Hence, Dr. Xun Xiao intends to solve the issue by employing ligand-modulated coordination management (LiMCOM) to develop a novel eco-friendly recycling system for a sustainable and circular perovskite PV system that goes beyond the state-of-the-art. ER intends to bring a low-cost, high-efficiency, and pollution-free solution for PeroPV waste by utilizing inter/multidisciplinary research involving physics, chemistry, materials science, and device engineering with the host institution's excellent infrastructural resources. The proposed project (ECOPV) complements the ER's expertise in lead-recycling for perovskite PV and the host scientist's knowledge of green solvent engineering. Overall, new expertise obtained via this fellowship will help ER mature in managing his future research group, ideally in Europe.

Keywords: perovskite photovoltaics,waste treatment,recycling,renewable energy,optoelectronics,emerging solar technology,circular economy
GENOMIC SURVEILLANCE TO CONTROL PATHOGEN INFECTIONS IN AFRICA (GenPath Africa)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Global Health EDCTP3
Action type: Research and Innovation actions
Partnership: EDCTP3 (JU-JTI)
Countries involved: South Africa,Mozambique,Kenya,Belgium,Germany
Call: Genomic epidemiology for surveillance and control of poverty-related and emerging/re-emerging infections in sub-Saharan Africa (HORIZON-JU-GH-EDCTP3-2022-01, 2022)
Start date: 2023-05-01
End date: 2027-04-30
Duration (months): 48.0
Total project cost (EUR): 4999170.25
EU funding (EUR): 4999170.25
Participants: 5
Project status: SIGNED

The overall goal of GenPath Africa is to control pathogen infections in Africa. Our consortium of African and European investigators proposes to build on our collective experience in responding to SARS-CoV-2 to better diagnose, monitor and clinically manage current and future epidemics in Africa. We propose to expand genomics capacity to combat drug resistant HIV-1 and TB through precision medicine and by using genomic epidemiology to guide the public health response. GenPath Africa will also apply recent developments in wastewater and one health surveillance to detect emerging pathogens. Capacity development activities will include degree training in South Africa and the transfer of technology to the National Public Health Institute of Mozambique. The consortium’s objectives will be achieved by connecting the specialized genomics facilities of the Africa CDC Pathogen Genomics Initiative (Africa PGI) in South Africa and Kenya with African national public health institutes to translate scientific advances into public health actions. Long-term collaborations with Germany and Belgium will be leveraged to help achieve these objectives and make precision medicine and precision public health a reality in southern and East Africa. The consortium will also contribute to the long-term capacity building objectives of Africa PGI by contributing to harmonising training resources and collaboration with existing networks to ensure that all data are of high quality and available in public databases. GenPath Africa will advance the EDTCP3 work program by: i) providing researchers and public health professionals with skills in genomic epidemiology to better understand infectious disease epidemiology and drug resistance, ii) strengthening capability in southern and East Africa to rapidly respond to current and emerging epidemics, and iii) providing researchers with training to advance their scientific careers in Africa and establish themselves as scientific and public health leaders.

Keywords: africa,drug resistant tuberculosis,wastewater surveillance
Advanced microbial oil production for a sustainable circular economy: microalgae and oleaginous yeast consortium using low-cost carbon sources (Oils4my)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,Belgium
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-01
End date: 2027-12-31
Duration (months): 24.0
Total project cost (EUR): 209914.56
EU funding (EUR): 209914.56
Participants: 3
Project status: SIGNED

The transition to renewable energies is urgent and necessary to reach independence from fossil fuels and consolidate the circular economy in the EU. Microbial oils are regarded as a promising raw material for sustainable production of bioproducts conventionally attained from petro-derivatives. However, microbial oil production viability depends mainly on cell performance and substrate cost. To cope with that, Oils4my will engineer and validate a high-performance novel platform capable of converting volatile fatty acids (VFAs) from anaerobic fermentation (AF) into microbial oils using oleaginous yeast and photosynthetic microorganisms. Oils4my will address three key scientific challenges: the viability of using VFAs from AF as a low-cost carbon source, understand the nutrient requirements of the proposed consortium to produce and accumulate lipids, and validate an integrated multi-stage process that enables high-performance microbial oil production at a technical and economic level. To overcome these challenges, first, an efficient separation of VFAs (from AF) through membrane filtration will be designed. VFAs will be then used as carbon sources for the microbial consortium and optimal parameters will be determined to produce and accumulate lipids in an oleaginous fermentation. As a green alternative, microbial oils will be extracted by enzymatic hydrolysis. The whole process will be validated in a multi-stage system to reach an oil content of 40-60% w/w and an oil extraction efficiency of 70%. Oils4my will demonstrate the feasibility of producing microbial oils using a waste stream derived from AF in a cost-effective process, contributing to the circular economy. The fellow, Dr. Marcela Levío-Raimán will conduct this action at the Institute of Sustainable Processes of the University of Valladolid under the supervision of Dr. Cristina González, with secondments at the University of Antwerp and Oleofat company and in collaboration with Forschungszentrum Jülich.

Keywords: microbial oil production,photobiorefinery,microalgae,oleaginous yeast,low cost carbon sources,volatile fatty acids
Human dimensions of biodiversity conservation: Wildlife trade, COVID-19 and geopolitics (HUMAN-CONSERVATION)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-12-01
End date: 2025-11-30
Duration (months): 24.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 1
Project status: CLOSED

The catastrophic global decline of biodiversity is one of the most pressing problems facing humanity. Effective conservation solutions must be informed by evidence. Conservation policy and practice historically relied solely on the natural sciences for guidance, but there is increasing recognition that considering the human dimensions of conservation is vital. These are complex and span diverse fields of classic and applied social sciences, and are particularly pertinent for problems which are inherently the result of human decisions and actions, such as wildlife trade. Wildlife trade is a major driver of biodiversity loss and a pathway for zoonotic disease transmission. Illegal and unsustainable wildlife trade is a significant threat, placing ~12,000 terrestrial vertebrate species (ca. one quarter of the total) at risk of extinction. Furthermore, the rising frequency of zoonotic epidemics and pandemics, including COVID-19, has highlighted the devastating human health consequences of wildlife consumption. Shifting global power structures and geopolitics add to the complexity of the challenges faced. Improved wildlife trade governance and environmental governance in biodiversity-rich areas is needed to manage zoonotic disease risks and implement integrated preventative approaches like One Health. How can wildlife trade governance address the challenges of our geopolitically polarized, post-pandemic world? In the HUMAN-CONSERVATION project, I will pursue three Research Objectives on the human dimensions of wildlife trade. Building on my expertise on the human dimensions of wildlife trade, my ability to lead interdisciplinary collaborations, and Prof. Di Marco’s strengths in comparative species modelling and in using integrated approaches to connect conservation solutions to broader societal goals like human health, the HUMAN-CONSERVATION project will inform wildlife trade policy, help combat wildlife trafficking, and define frontiers in conservation geopolitics.

Keywords: biodiversity conservation conservation social science wildlife trade wildlife trafficking geopolitical tensions
Hybrid Electrochemically-paired Light Irradiated Organic Synthesis (HELIOS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-11-01
End date: 2028-10-31
Duration (months): 60.0
Total project cost (EUR): 1499828.0
EU funding (EUR): 1499828.0
Participants: 1
Project status: CLOSED

The synergy of visible light and electrical energy has been employed for decades in water splitting to hydrogen, but only recently was used to power the synthesis of higher value complex organic molecules (natural products, pharmaceuticals). Synthetic photoelectrochemistry (PEC) is receiving notable attention due to its enhanced scope of redox transformations, sustainability, and selectivity compared to photo- or electrochemistry alone. Synthetic electrochemistry (EC) is a useful synthetic tool that replaces atom-uneconomical chemical redox agents with simple electrons and protons. However, in most EC reactions and in all PEC reactions, only one half-reaction of the cell is optimized to generate value; the other half-reaction sacrifices its own electrode or redox additives. ‘Paired’ electrolysis, where both half-reactions afford useful species, is key to sustainability and efficiency. HELIOS will discover, develop and disseminate paired synthetic PEC reactions. Intermediates generated by both half-reactions are converged in novel, creative chemical transformations, including: i) marriage of radicals or ions generated by each half-reaction to furnish phenethylamines and azetidines, valued pharmaceuticals ii) ring-fusing reactions that furnish bicyclic scaffolds, toward molecules with high 3D character urgently required in drug discovery iii) alcohol inversion reactions that are catalytic, environmentally-friendly and use mild conditions ‘Multifunctional’ catalysts will be used that can be electro-activated in both cathodic and anodic half-cells, to photochemically generate and stabilize reactive intermediates. HELIOS i) harnesses electrical and light energy to rapidly convert cheap, abundant chemical feedstocks to value-added complex molecules and ii) improves the sustainability and selectivity of synthetic PEC and EC processes. HELIOS opens an entirely new dimension of chemical reactivity that will revolutionize the way chemists use redox to synthesize molecules.

Keywords: photoelectrochemistry radical chemistry synthetic method development green chemistry
Generative Polymer Informatics (genPI)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1498891.0
EU funding (EUR): 1498891.0
Participants: 1
Project status: SIGNED

Embarking on a transformative journey, this groundbreaking research proposal unveils generative polymer informatics (genPI)-a revolutionary paradigm that leverages the unprecedented capabilities of transformer-based artificial intelligence to catapult polymer discovery, design, and development into a new era. In a time when sustainable and advanced materials are more crucial than ever, genPI aims to overcome key challenges in polymer science by exploring vast chemical spaces, accurately predicting properties, generating novel structures with targeted functionalities, and forecasting synthesis feasibility. The project is strategically organized into three interconnected work packages: rapid exploration of polymer chemical spaces (WP1), creation of customized polymer structures (WP2), and prediction of synthesis routes (WP3). These are supported by transversal activities that ensure data extraction, workflow integration, and democratization of tools and knowledge. By harnessing machine learning techniques, genPI endeavors to invert the traditional polymer design paradigm, empowering the creation of polymers with precisely engineered properties. This pioneering approach holds the promise of unveiling entirely new classes of polymers with unprecedented characteristics, directly addressing pivotal issues such as environmental sustainability, advanced functionality, and innovative synthesis methods. The project's inherently interdisciplinary nature-melding materials engineering, polymer science, and artificial intelligence-positions it at the vanguard of materials science innovation. Its successful implementation could revolutionize industries from sustainable manufacturing to healthcare, paving the way for a new era in polymer science aligned with global sustainable initiatives. This research not only promises to accelerate polymer discovery but also democratizes access to the advanced built tools, fostering collaboration and innovation across academia and industry.

Keywords: polymers,data driven,polymer informatics,generative large language models,polymer property prediction,polymer space exploration,polymer synthesis predictors