Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Direct detection of coherent signals using Fano devices (Fano Detector)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-06-01
End date: 2023-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

This ERC PoC project aims to explore the commercial potential of a new and promising approach for realizing cheap integrated detectors with low energy consumption for use in high-speed interconnects, e.g. within datacenters. The innovative idea behind these new types of devices, denoted Fano Detectors, is based on high-quality research carried out under our ERC AdG “FANO”. Our long-term goal is to establish a start-up company and develop a transceiver product that can directly be sold to datacenters such as Facebook and Google. The main activities in this project focus on maturing the technology, investigating the product feasibility, and developing the business case to establish the foundation for a start-up company. To mature the technology, we will develop a portable demonstration unit (PDU) and test advanced functionalities of the Fano Detector. This PDU will be used to demonstrate our technology at trade fairs and conferences facilitating early engagement with customers. The product feasibility study will enable us to determine whether it is possible to develop a full transceiver product by a tech start-up or not. Based on our determined position in the market from the product feasibility study, we will build the required team and prepare a business plan. The deliverables of the project are a Fano Detector PDU, bill of materials, product specification sheet, and a business plan. A technical risk is the present low-resolution fabrication offered by foundries. We have identified an alternative design to mitigate this. The commercial risk is that it could be too ambitious for a start-up to build a full transceiver product. In this case, alternate routes such as licensing of the technology or partnering with OEMs will be considered. Market reports show that the revenue of datacenter optical transceivers will continue to grow at a CAGR of 15% reaching $11B by 2026. The optical transceiver market remains fragmented with a low barrier of entry for new tech companies.
Terahertz Integrated Biosensing from molecular, vesicular to the cellular and tissue level – TeraIBs (TeraIBs)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Netherlands,Germany,Spain,Lithuania,Italy,France
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 2865196.8
EU funding (EUR): 2865196.8
Participants: 15
Project status: SIGNED

THz biosensorics is a strongly growing field of research, as many biomolecules and biomolecular complexes exhibit application-relevant intramolecular and intermolecular resonances in this frequency range, with great potential for a wide range of biomedical and diagnostic applications. The TeralBs project aims to develop a radically new technology based on THz radiation for biomedical detection and diagnosis, based on a team of Doctoral Candidates (DCs) with the necessary in-depth background in devices and systems, spectroscopic techniques and biomedical measurement knowledge using THz radiation. To this end, all DCs projects are built around three major technological challenges of THz technology for biomedical applications: the development of cost-effective, sensitive, integrated THz technologies; the exploitation of the high specificity multi-analyte capabilities of THz; and the development of flexible and reliable THz analytical instrumentation and robust information extraction. The DCs projects configure a research programme structured in three research lines, which guide all technological developments in the project: RL1 on biomolecules, RL2 on vesicles and viruses, and RL3 on organ-on-chip sensing. At the end of the project, all the technological developments will be brought together in three demonstrators: a modular all-electronic system for the read-out of metamaterial-based THz biosensors, a fully integrated photonic THz sensor for biomedical applications, and an organ-on-chip model that will be used to validate the different THz sensors and technologies developed in the project in a biomedical-relevant scenario. The multidisciplinary knowledge gained by the DCs will enable them to explore new concepts in the broad field of future biomedical applications, equipped with an attractive set of transferable skills relevant to innovation, long-term employability, and leadership in the field of biomedical applications and THz technologies.

Keywords: keywords exosomes metamaterials near field microscopy,microfluidics,micro integration,single cell analysis,modeling,biomedical application
ParentPOWER: Public engagement to support families in crisis (ParentPOWER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Public Engagement with Research Award
Action type: Recognition Prize
Countries involved: United Kingdom
Call: ERC-2024-PERA (ERC-2024-PERA, 2024)
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 1
Project status: SIGNED

When a crisis hits, families are deeply affected. From COVID-19 lockdowns, to war in Ukraine, to floods in Pakistan, parents are caring for children under conditions of extreme distress. Within an ERC Consolidator award, we partnered with UN agencies, NGOs, businesses, and the general public to develop a global dissemination effort to support families. Together, we developed and shared evidence-based parenting support resources to caregivers of children in pandemic, climate, and conflict crises across the world. This included a hackathon with staff members of Generali Insurance, who translated parenting resources into over 30 languages; faith-based networks that adapted parenting advice across multiple communities; over 240 non-governmental organisations; and 33 governments that adopted our resources in their national emergency responses. It also included citizen-led innovation: animators developed videos, and musicians created an evidence-based parenting song that was downloaded 15,400 times. This public engagement led to an unprecedented reach of parenting support for families in crisis: 210 million in the COVID-19 pandemic, and 11 million during war and climate disasters in Ukraine, Turkiye, Syria, Afghanistan, Pakistan, Palestine, Israel, and Sudan. Our qualitative research in ten countries found that resources were highly valued (Sherr & Mebrhatu 2022). Quantitative surveys led by local NGOs in Ukraine and Pakistan showed significant improvements in parent mental health, non-violent discipline, positive parenting, and play. With a goal of reaching every family in the world, we learned essential lessons about public engagement with research. First, that we had to collaborate far beyond our anticipated partnerships. Second, that citizen-led groups can sensitively adapt research to their contexts, whilst maintaining the evidence base. And finally, that when science and the public join forces, incredible impact is possible.

Keywords: parenting support child abuse prevention covid 19 global dissemination and impact policymakers ngo partnership private sector partnership pandemic,conflict and climate crises
LINEup - Longitudinal data for INequalities in Education (LINEup)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Social and Economic Transformations
Action type: Research and Innovation actions
Countries involved: Italy,Portugal,Spain,France,Greece,Germany
Call: Mapping of longitudinal data and assessment of inequalities in education, training and learning achievements (HORIZON-CL2-2023-TRANSFORMATIONS-01, 2023)
Start date: 2024-02-01
End date: 2027-01-31
Duration (months): 36.0
Total project cost (EUR): 2814203.75
EU funding (EUR): 2814203.75
Participants: 15
Project status: SIGNED

LINEup aims at identifying key success factors for quality education for all, by mapping and analysing the research design and findings of existing longitudinal data on students’ learning outcomes at primary and secondary level (6-18 year-old students). Considering that 2023 is the European Year of Skills and in line with the objectives of the European Education Area and Council Recommendation on Pathways to School Success, the project focuses on achievement and attainment of basic skills. LINEup is based on a comprehensive desk research aiming at collecting, analysing and summarizing data that allow assessing inequalities in education over time in 31 countries, and with a particular focus on Southern and Western Europe. Part of the activities are dedicated to understand to what extent different databases can be made directly comparable and deliver a feasibility study that brings innovation to the research community interested in comparative longitudinal analysis. A qualitative research in project countries complements the mapping to gather primary data on the implementation process and impact of possible compensatory interventions. In line with the findings of recent longitudinal studies, the objective is to further investigate what schools can do to keep their students engaged, meet their characteristics and needs, and reduce inequalities in the short, medium and long run. LINEup will contribute to expand the knowledge base on what shapes educational outcomes over time and on student-centred interventions aiming at lifting the performance in basic skills and reducing early leaving from education and training, which are a key challenge across Europe. Attention will be dedicated to cooperating with national authorities of the participating countries to identify and access longitudinal data and other administrative sources, and to validate and disseminate the results at European, national and local level for a more supportive and equitable school environment.

Keywords: longitudinal data,equity,quality,education,students school engagement
Multidimensional interferometric photoelectron spectroscopy with extreme ultraviolet photons (MULTIPLEX)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-08-01
End date: 2028-07-31
Duration (months): 60.0
Total project cost (EUR): 1577500.0
EU funding (EUR): 1577500.0
Participants: 1
Project status: SIGNED

Photochemical reactions are the central driving force in nature and in sustainable technologies. Understand-ing photochemical reactions on the quantum level is thus a primary goal in science. However, this task re-mains a major experimental and theoretical challenge even on the single-molecule level due to the involved ultrafast time scales, predominantly nonradiative processes and strongly coupled degrees of freedom. Methods are needed that provide a gap-less view on the molecular mechanisms with the necessary sensitivity and selectivity to uncover and disentangle the participating reaction pathways. In this project, we will for the first time establish ultrafast multidimensional extreme ultraviolet (XUV) photoelectron spectroscopy to solve this problem. This method is capable of mapping photochemical processes with unprecedented spec-tro-temporal resolution along the entire reaction coordinate, while unraveling otherwise degenerate path-ways in multidimensional correlation maps. This becomes possible with the unique combination of concepts from coherent multidimensional spectroscopy with femto to attosecond XUV light sources and photoelectron spectroscopy. As spectroscopic probes, well-controlled model systems will be investigated, ranging from isolated, cold molecules and molecular complexes to individual species embedded in tailored nano-cluster environments. The proposed project will (a) establish laboratory-based high-resolution XUV photoelectron spectroscopy as a widely accessible alternative to experiments at synchrotron and free-electron-laser facilities (b) introduce the concept of coherent multidimensional photoelectron spectroscopy (c) develop new theoreti-cal analysis methods of transient multidimensional photoelectron data (d) resolve the details of fundamental intra and intermolecular photochemical processes including elusive non-adiabatic and quantum coherence mechanisms (e) elucidate the role of tailored environments in molecular dynamics.

Keywords: photoelectron spectroscopy,extreme ultraviolet spectroscopy,coherent multidimensional spectroscopy,molecular dynamics,ultrafast dynamics,non adiabatic dynamics
Deciphering the antibody-microbiota axis in early life (EarlyMicroAbs)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 1650000.0
EU funding (EUR): 1650000.0
Participants: 1
Project status: SIGNED

Immunoglobulins (Igs) are thought to influence formation of the microbiota composition during a critical window of opportunity in early life. Yet, the antigen binding profiles of these Igs are vastly unknown, and it is incompletely understood how early misguided immune education contributes to the development of allergies or asthma. On an even more fundamental level, it is also unclear if or how B cell receptor (BCR) sequences of different individuals converge to binding similar microbiota antigens and how such responses form in early life. Here, we will leverage phage display as well as novel approaches to study BCR sequence/Ig function relationships, focusing on the following objectives & research questions: a) How do immune exposures in early life shape Ig repertoires and influence health later on? We hypothesize that Ig repertoire development depends on the birth mode, duration of breast feeding, & antibiotics treatments. Here, we will deeply profile the Ig repertoires of mother-child dyads against 600,000 rationally selected microbiota antigens. We will also study the immune repertoires of children with allergies and mine these data sets for associations with early life Ig data sets. b) Do BCR sequences of different individuals converge to binding similar antigens? As observed for some viral antigens, we hypothesize that also universal responses towards bacterial antigens exist and we can capture such sequences in early life. We will apply state of the art and novel proprietary methodologies to link BCR sequences with Ig binding in adults & infants. Linking BCR sequence information with the actual antigen targets, will contribute to understanding the sequence-function relationship of Ig binding and their formation in early life. Deep profiling of mother-child dyads will provide new insights to the development of Ig repertoires. By comparing these datasets with allergic children may also reveal links between early immune education & lasting impacts on health.

Keywords: microbiota,antibody repertoires,bcr sequences,window of opportunity,machine learning,data scienc,bioinformatics
Crop Wild Relatives utilisation and conservation for sustainable agriculture (COUSIN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Research and Innovation actions
Countries involved: Spain,Portugal,Belgium,Italy,Greece,Denmark,France,Hungary,Netherlands,Switzerland,United Kingdom,Germany
Call: Crop wild relatives for sustainable agriculture (HORIZON-CL6-2023-BIODIV-01, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 5677697.5
EU funding (EUR): 5677697.5
Participants: 26
Project status: SIGNED

Crop Wild Relatives (CWRs), i.e. the COUSINs of domesticated crops, represent a natural source of genetic variation. The COUSIN consortium recognizes the value of CWRs for agriculture, but also the challenges of their utilisation. Through the COUSIN Readiness Levels (CRLs) we will demonstrate a roadmap for the use of CWRs in breeding and farming. We will work with five flagship crops: wheat, barley, pea, lettuce and brassicas. With these exemplary crops, we demonstrate how current challenges of stakeholders from farm to fork can be overcome using CWRs in formalised and participatory breeding. The COUSIN consortium has unique CWR-related expertise, data and breeding material that allows us to cover the translational pathway from the identification of wild plants to a market-ready crop in a five-year project. For each flagship crop, we identify priority traits of CWRs, design selection toolboxes and apply them in current breeding programmes in order to fulfil current and emerging stakeholders demands. Effective characterisation protocols are designed and will guide conservation of the naturally occurring functional and genetic trait diversity across Europe. Characterisation will occur in- and ex-situ through high-throughput phenotyping, chemotyping and genotyping of priority traits incl. plant-associated microbiomes. Conservation measures cover in-situ reserves and ex-situ collections with the widest possible trait diversity. For easy access of priority trait information and corresponding CWR accessions, a user-friendly data portal will be developed. All collected data will be offered for integration into national and international repositories. Through on-farm pilots and actual breeding sites realised across the European pedoclimatic regions, the value of CWRs will be demonstrated to stakeholders with direct applications for breeders and farmers to provide climate change-resilient crops as a vital means towards sustainable production systems.

Keywords: wheat,barely,pea,broccoli,brassica,rapeseed,lettuce,pre breeding
Graphene Transistors for High-Density Brain-Computer Interfaces (GphT-BCI)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain
Call: EIC Transition Open 2023 (HORIZON-EIC-2023-TRANSITION-01, 2023)
Start date: 2023-12-01
End date: 2026-11-30
Duration (months): 36.0
Total project cost (EUR): 2495000.0
EU funding (EUR): 2495000.0
Participants: 2
Project status: SIGNED

We have developed a novel type of graphene-based transistors capable of delivering high-resolution brain mapping, implementing multiplexing strategies, and monitoring activity across a wide range of frequencies, including low frequencies. We circumvented the bottlenecks faced by other approaches thanks to the unique properties of graphene. Graphene is an outstanding conductor and provides the perfect platform for multiplexing. Thus, our system requires much fewer wires than current alternatives. Further, graphene is just one atom thick, flexible and can be integrated into ultra-soft flexible substrates, providing excellent contact with brain tissue. Our graphene transistor technology has been developed as part of the FET-Graphene Flagship and FET-proactive BrainCom projects. We have assessed the technology in rodents and demonstrated that our devices allow monitoring brain activity with very high spatial resolution and over a wide bandwidth frequency range. This project will pave the way for the clinical translation of brain-mapping neural interfaces based on graphene-transistor arrays for brain-computer interfaces.

Keywords: cortical grids,brain computer interfaces,brain mapping
Translational Microbiome Platform (MICK)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator Open 2021 (HORIZON-EIC-2021-ACCELERATOROPEN-01, 2021)
Start date: 2022-09-01
End date: 2025-02-28
Duration (months): 30.0
Total project cost (EUR): 3080973.75
EU funding (EUR): 2156681.63
Participants: 1
Project status: CLOSED

Dysbiosis (the imbalance of the microbial community that resides within and upon us) can affect health and represents a risk factor for the genesis and evolution of a plethora of chronic diseases and pathologies. The analysis of the microbiome is necessary to detect, assess and monitor it. Nevertheless, microbiome analysis and its application to the clinical field is very complex, expensive, and time-consuming. We created MICK, the first digital decision support system helping healthcare professionals in integrating microbiome analysis into clinical practice. MICK automated platform analyses microbiome raw data in real-time, with the highest accuracy and translates it into evidence-based analytics, insights, and practical recommendations. MICK allows customers (clinical centres and diagnostics labs) to scale their service offering to patients without any upfront investment, determining up to 75% cost reduction and faster TAT compared to existing solutions.

Keywords: bioinformatics,microbiology,biotechnology,ict,health,e health