Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Impact of emotions on learning and memory-related brain processes across development: an application to climate-related educational issues (Emotiv4climate)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium,Canada
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 200400.0
EU funding (EUR): 200400.0
Participants: 2
Project status: SIGNED

Providing large-scale sustainability education programs, in particular regarding climate issues, is critical to quickly implement the profound socio-ecological transformations expected by the mid-21st century. Although climate awareness is growing, current education policies -which mainly warn the risks of climate change, therefore focusing on negative contents- struggle to reach their objectives, as misinformation and poor knowledge assimilation persist. Yet, recent advances in neurosciences suggest that while negative emotion strengthen the memory of the emotional element, it disrupts associative memory, which is essential for the development of complex multivariate representations. Leveraging cutting-edge neurophysiological techniques (magnetoencephalography, electroencephalography), Emotiv4climate hypothesizes that positive emotions will enhance associative memory due to the selective integration of the newly learned information within hippocampus-dependent networks that promote their binding. And that positive memories will benefit more from sleep-dependent consolidation processes than negative ones, favouring their integration within pre-existing knowledge. Using ecology-themed material and questionnaires, Emotiv4climate will elucidate the differential impact of emotions (positive vs negative) on the behavioural and functional brain connectivity processes associated with learning and memory processes with an applied dimension to climate-related educational issues. Our understanding will benefit from a developmental approach comparing young adults and school-aged children with different maturational levels in terms of sleep-dependent memory consolidation processes. Emotiv4climate will hence not only uncover the cognitive and neurophysiological mechanisms through which emotions impact learning and memory consolidation throughout development but also help designing optimized communication and education strategies likely to catalyse sustainable behaviour.

Keywords: declarative learning,memory consolidation,emotions,sleep,children,cognitive development,magnetoencephalography,brain connectivity,theta activity,salience tag
Socialist symbolic geography and global belonging: Yugoslav travel writings in the Third World (SOCGLOBE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Croatia
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-04, 2022)
Start date: 2024-11-01
End date: 2026-10-31
Duration (months): 24.0
Total project cost (EUR): 161889.6
EU funding (EUR): 161889.6
Participants: 1
Project status: SIGNED

European socialist travel writers in the previous century turned their course to Africa and Asia, reflecting the fact that the Second and Third Worlds formed a close political, economic and cultural alliance, which was built on a popular and widely accepted vision of mutual interconnectedness and global belonging. The socialist travelogue had an important role in promoting such symbolic geography and in negotiating proclaimed and practiced solidarities with various tensions, interests and power inequalities. Today, these travelogues and the partnership between the two worlds have been forgotten, profoundly influencing how we understand the European – and global – past and future. SOCGLOBE sets to examine the Yugoslav socialist travelogue (1945–1990), as a rich place to explore socialist symbolic geography and, consequently, promote values, narratives and memories of solidarity and global belonging in order to re-inspire public debates on the European future. In line with that, SOCGLOBE has two strategic goals: (1) to compose the first comprehensive corpus of Yugoslav travel writing, thus integrating the uncatalogued material in danger of historical disappearance, and (2) to build a novel conceptual framework to explore socialist symbolic geography beyond the currently dominant postcolonial model, created for analysing relations between Western Europe and its (colonial) Other(s). SOCGLOBE challenges the postcolonial approach by incorporating imagology and Bourdieu’s concept of position-taking into the research and proposes the notion of socialist symbolic geography as a site of multidimensional and multidirectional exchange and negotiation. SOCGLOBE advances literary-, cultural- and travel writing studies beyond their Western-oriented focus, and contributes to socialist studies, historical research on Second and Third World relations and broader research on (semi-)peripheries by proposing an alternative conceptual model for framing intercultural relations.

Keywords: socialist travel writing,yugoslavia,third world,symbolic geography,solidarity,global belonging
Towards a sustainable and accepted 6G for Society (6G4Society)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Smart Networks and Services
Action type: Coordination and support actions
Partnership: SNS (JU-JTI)
Countries involved: Netherlands,Greece,Belgium,Cyprus,Switzerland,Italy
Call: SNS Societal Challenges (HORIZON-JU-SNS-2023, 2023)
Start date: 2024-01-01
End date: 2025-12-31
Duration (months): 24.0
Total project cost (EUR): 1072458.46
EU funding (EUR): 999534.95
Participants: 7
Project status: SIGNED

The 6G4Society project aims to address the tension existing between two parallel needs in terms of technological development of 6G: 1) securing technology performance objectives, and 2) ensuring that societal and sustainable values are properly embedded into technology. This will be done by engaging all key stakeholders within the Smart Networks and Services (SNS) ecosystem, but also by embracing civil society players, regulators, policy makers, media, and the public at large, to ensure correct and clear information about the expected impacts 6G technology will produce and induce is elaborated and disseminated. To achieve this objective, 6G4Society will apply methodologies from ethics, legal and social science and humanities (SSH) perspectives, allowing to comprehend socio-cultural aspects and mechanisms behind 6G technology and lay the foundation for a responsible research and innovation (RRI) of 6G technology. Based on these methodologies, 6GSociety will provide methods, models, guidelines, policy options and operation recommendations to develop sustainable and socially accepted 6G technology and applications. The 6G4Society results (including a Technology Acceptance Model for 6G technology, a framework of Key Sustainability Indicators, a policy brief and an operation brief) will be validated with all 6G-SNS JU projects by adopting public and user engagement methodology, as well as by involving the 6G-IA Working Groups and its connected projects. To achieve these ambitious objectives, the 6G4Society project is composed by a consortium with heterogeneous skills and competence, ranging from SSH and RRI (CEL and PSCE), technology (NOVA, PSCE and EBOS), networking coordination and management (MAR), communication and stakeholder engagement (D4P). The consortium has large experience in 5G-PPP/6G-IA projects and initiatives, and its partners have links with more than 20% of the current JU 6G-SNS initiatives, ensuring a strong cooperation to achieve objectives.

Keywords: sustainability,technology acceptance model,6g,public and non experts engagement,societal impact,policy options,6g ia working groups,operation recommendations
Design Al alloys with ultimate properties through Multi-scale modelling of Precipitation Kinetics (DAMPK)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 194074.56
EU funding (EUR): 194074.56
Participants: 2
Project status: SIGNED

Design high strength Al alloys is essential for industrial light-weight designs for both environmental and economic sustainability. This is usually achieved through age-hardening, where nanometer-sized precipitates are introduced to hinder dislocation slip. Accurate control of their size, spatial distribution and number density during aging is crucial to develop alloys with optimal performance. However, the assessment of precipitation kinetics and optimization of thermo-mechanical processing routes have been traditionally relying on costly experimental “trial-and-error” approaches. In this project, a novel methodology is presented to accurately determine the precipitation kinetics in Al Alloys based on the combination of first principles calculations and classical nucleation, growth and coarsening theories. The strategy is based in two main pillars. The first one is using first principles calculations and statistical mechanics approaches to determine precipitate thermodynamic parameters in Al alloying system, with consideration of influence of temperature and precipitate/solute state. The second one is the combination of this information with classical precipitation and strengthening theories to predict the precipitation kinetics and strengthening during heat treatment. The results will be validated experimentally and the developed strategy will be used to develop novel high strength Al alloy. The approach developed in this proposal will improve the predictive power of Integrated Computational Materials Engineering in Al alloys. The applicant will transfer his expertise and international connection in the field of precipitation kinetics characterization and modeling to the host institute. He will work with researchers of the host institution to prompt new areas of research that can attract new funding and receive regular training on transferable skills. All these activities will enlarge his portfolio of skills and will ensure further development of his career.

Keywords: al alloys,precipitate,precipitation kinetics,precipitate strengthening,first principles,statistical mechanics,monte carlo,mean filed simulation,orowan theory
Stapled peptide analogues as inhibitors of the CCR4-NOT complex to regulate the mRNA degradation (StapPep)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-06-01
End date: 2024-05-31
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: CLOSED

RNA has gained significant attention in the past few decades due to its evolutionary role in gene regulations. In the regulation process RNA seldom works as an individual entity rather associated with several protein-protein complexes (PPCs) and those complexes play a key role in mRNA maturation. Typically, mRNA undergoes different post-transcriptional modifications and deadenylation is one of those post-transcriptional events in which shortening of the poly(A) tail at the 3’ end of mRNA occurs and it plays a major role in mRNA stability. Deadenylation is often regulated by different PPCs and dysregulation of these complexes severely impaired this process. In fact, in many cancer cells shortening of poly(A) tail has been found due to the non-specific deadenylation event. Therefore, Chemical modulators that can regulate the deadenylation process have immense therapeutic importance. CCR4-NOT is one of the most studied deadenylase complexes which actively participate in the deadenylation process. Several types of mRNA-associated proteins (NOT4, Bam, and Roquin) are known which recruit RNA to the CCR4-NOT complex for deadenylation by interacting with CAF40 through its evolutionary conserved site CAF40 binding motif (CBM) domain. Moreover mRNA-associated proteins and RNA both share the same binding surface of the CAF40 protein. Therefore, blocking the interaction between CAF40 and RNA would serve the inhibitory activity of the CCR4-NOT complex towards the deadenylation process. From crystal structure, it has been found that the CBM domain of Bam protein interacts with the CAF40 protein through its α-helical surface. Here in this proposal, we will design α-helical hydrocarbon stapled peptide analogues of CBM domain to exploit the protein-RNA interaction by regulating the activity of CCR4-NOT complex towards deadenylation process. Several biophysical, computational, and cell-based assays will be utilized to investigate the activity and mechanism of deadenylation process.

Keywords: stapled peptide,deadenylation,cell permeability,mrna,caf40,solid phase peptide synthesis
Emerging Two-phase Expansion Power Generation Technology – Unlocking the Potential of Geothermal and Industrial Waste Heat Utilization (EMPOWER)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Cross-sectoral solutions for the climate transition
Action type: Research and Innovation actions
Countries involved: Denmark,Romania,Netherlands,Italy,Belgium
Call: Emerging energy technologies for a climate neutral Europe (HORIZON-CL5-2024-D2-01, 2024)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 2498475.0
EU funding (EUR): 2498475.0
Participants: 7
Project status: SIGNED

Geothermal energy utilization and industrial waste heat recovery are gaining recognition as valuable contributors to sustainable energy production. While geothermal and waste heat sources above 150 °C are commonly exploited, low-temperature sources below 150 °C, which are more abundant and have even greater potential for power generation, remain largely untapped due to economic and technological constraints. The EMPOWER consortium aims to revolutionize low-temperature energy conversion by developing a new generation of organic Rankine cycle technologies adopting a holistic approach. Specifically, we will (1) design and analyse next-generation two-phase turbines, exploring a novel reaction configuration, (2) raise the Technology Readiness Level (TRL) of reaction two-phase turbines from TRL 2 to TRL 4 by validating the concept in a novel dedicated experimental facility, (3) incorporate realistic two-phase turbine performance data into the techno-economic analysis and optimization of the partial-evaporation organic Rankine cycle systems, (4) conduct a Life Cycle Assessment (LCA) to quantify and minimize the environmental impact of the technology in the context of geothermal energy utilization and waste heat recovery from the European cement and steel industries, and (5) evaluate the social and economic benefits and barriers of deploying this technology and design strategies to exploit the benefits and mitigate the barriers. The consortium consists of 7 partners (5 beneficiaries and 2 associated partners) – 3 academic partners and 4 industrial partners – from 5 countries. The consortium's composition, complemented by an External Advisory Board with representatives from other EU-funded projects and key stakeholders from targeted industries, ensures a push-pull drive that will maximize progress towards our common objectives. Overall, EMPOWER aims to deliver an emerging, sustainable technology contributing to a cleaner, more energy-efficient future for Europe.

Keywords: geothermal energy industrial waste heat recovery low temperature heat recovery organic rankine cycle power system two phase turbomachinery
Improving quality and patient SAFEty in surgical care through STandardisation and harmonisation of perioperative care in Europe (SAFEST)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Ensuring access to innovative, sustainable and high-quality health-care
Action type: Research and Innovation actions
Countries involved: Spain,Netherlands,Portugal,Estonia,Czechia,Germany,Belgium
Call: Enhancing quality of care and patient safety (HORIZON-HLTH-2021-CARE-05, 2021)
Start date: 2022-06-01
End date: 2026-05-31
Duration (months): 48.0
Total project cost (EUR): 4998778.75
EU funding (EUR): 4998776.0
Participants: 13
Project status: SIGNED

Adverse events in health care are suffered by between 8% and 12% of patients admitted to hospitals in the EU and are accountable for around EUR 21 billion in direct costs. Surgical adverse events are one of the most common types reported. The SAFEST project aims at improving and harmonising perioperative patient safety by establishing widely supported perioperative patient-centred EU standardised practices to address this challenge. SAFEST goes beyond state of the art in surgical patient safety by addressing the whole perioperative patient?s pathway (beyond the hospital care), thus ensuring the continuum of care. Patients will participate as co-equal partners throughout the project. Their engagement will start with the broad European consensus, jointly with other key stakeholders, to design the SAFEST standardised practices for perioperative care. The SAFEST standardised practices will be implemented in 10 hospitals from 5 EU countries through a Perioperative Quality Improvement Learning Collaborative (PQILC). Our evaluation of the implementation, both from a process and a results perspective, will allow assessing the impact of the implementation of standardised practices on the improvement of clinical outcomes and to identify contextual facilitators and barriers at micro, meso and macro levels, providing new evidence to translate standardised, evidence-based guidelines to clinical practice. The uptake of the SAFEST standardised practices will be taken a step further by inviting 100 hospitals across EU-27, associated countries and beyond, to self-evaluate and create an international benchmarking assessment. Furthermore, we will ensure that SAFEST makes an impact beyond its lifespan, with ambitious dissemination and exploitation plans that include launching an open-access benchmarking platform for European hospitals and constituting an international network on perioperative patient care.

Keywords: patient safety,perioperative care,standardised practices,patient empowerment
Composition Operators on Spaces of Dirichlet Series and Algebrability in Banach Algebras (CoDSABA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-05-01
End date: 2027-04-30
Duration (months): 48.0
Total project cost (EUR): 124957.44
EU funding (EUR): 124957.44
Participants: 1
Project status: SIGNED

This project will investigate timely questions on composition operators acting on Banach spaces of Dirichlet series, and on hypercyclic algebras. These topics are currently the subject of great mathematical interest, however fundamental questions remain unresolved in the respective fields. The first objective is to advance the theory of Banach spaces of Dirichlet series by employing operator theoretic function theory to understand the topological structure of the set of composition operators acting on these spaces. An effective method of achieving this is to study approximation numbers of differences of composition operators. This project will determine the rates of decay of approximation numbers of differences of composition operators acting on spaces of Dirichlet series, and characterise the linear combinations of composition operators acting on general Banach spaces of Dirichlet series. The second objective is to investigate the algebraic structure contained in the set of hypercyclic vectors of multiplication operators acting on the Banach algebra of compact operators. Hitherto work in this area has mostly been in the setting of Fréchet algebras, so this project will advance the theory for Banach algebras, and ultimately to identify whether every Banach algebra supports a hypercyclic algebra. Interest among the wider mathematical community in the findings of this project stems from its natural connections to some of the most important open questions in mathematics. In particular the study of Hardy spaces of Dirichlet series is related to the Riemann zeta function, and the investigation of hypercyclic algebras has a natural connection to the Invariant Subspace Problem. The scientific breakthroughs resulting from this project will also impact on a wide scientific community, where the results and methods will potentially find applications in dynamical systems, mathematical physics, physics, computer science and quantum information theory.

Keywords: dirichlet series,linear dynamics,composition operators,hardy spaces of dirichlet series,hypercyclicity,approximation numbers,algebrability,banach algebras of operators,hypercyclic algebras