Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Immediate, ubiquitous and affordable image diagnosis combining the power of AI, smartphones and 3d printing to achieve Universal Diagnosis by 2030 (SpotLab)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-11-01
End date: 2022-04-30
Duration (months): 30.0
Total project cost (EUR): 2245937.5
EU funding (EUR): 1572156.25
Participants: 1
Project status: CLOSED

Early detection of both infectious diseases and chronic diseases plays a crucial role in all treatment and prevention strategies. Population ageing and healthcare budget pressures do not contribute to ease the pain under this scenario. Optic microscopy is still the gold standard for diagnosing several tens of pathologies. However, physicians have been using almost the same technology to detect diseases for the past 150 years, by manually reviewing samples under a microscope. This requires the time of an expert analyst at the right place and at the right moment as the sample is been taken, something not always available and affordable. SpotLab’s solution sits in the convergence of the physical and the digital world to reduce time, costs and distances of microscopy diagnosis. SpotLab is a diagnosis-as-a-service company based on three technological pillars: (1) a smartphone transformed into a portable, intelligent and low-cost medical device, manufactured with 3D printing and consumer electronics, (2) a flexible and easy to use telemedicine platform that can be tailored to multiple diagnosis protocols that is connected to the knowledge of worldwide physicians; and (3) a factory of AI models that prioritizes cases and assists diagnosis for multiple pathologies. After 5 years of research at the Universidad Politécnica de Madrid, SpotLab S.L. was founded in 2017. We are a multidisciplinary orchestra with a diverse team of 14 people, internationally awarded and recognized by our capacity of creating responsible innovation and products in the digital health space. SpotLab´s seed round allowed us to bring our product to TRL6. We need EU funding to complement our new investment round and industrialize our product (TRL6 to TLR9), obtain the relevant regulatory certifications (CE Mark); and validate its market disruption in dif SpotLab´s team motivation is to create a positive impact in the world. We prefer to provide 1 million diagnoses at €1 than 1 diagnosis at €1 million

Keywords: massive infectious diseases,chronic diseases
Not for sale! Explaining the Outcomes of Neighbourhood Mobilisations Against Displacement (NOMAD-Outcome)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France,Canada
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 262385.28
EU funding (EUR): 262385.28
Participants: 2
Project status: SIGNED

A decade after the outbreak of the 2008 financial crisis, affordable housing-related displacement has become a global problem. Although displacement has captured the attention of urban sociology, social resistance to it remains understudied. The aim of this project is to fill this gap and explain the diverse outcomes of neighbourhood-based mobilisations opposing displacement through a qualitative comparative analysis of three cases (Parc-Extension in Montréal, Poble Sec in Barcelona and La Guillotière in Lyon). The research will shed light on three types of outcomes: favourable media coverage, social recognition and influence of public agenda. The project builds on the assumption that the capacity to generate outcomes depends on collective action mechanisms: the diversification of protest tactics, the forging of wide coalitions and the desingularisation of the idiosyncratic experience of the neighbourhood. Another aim of the project is to produce an oral history archive of the three neighbourhoods, which will contribute to foster knowledge transfer between academia and society. This GF proposes: a) an outgoing period to Centre Urbanisation Culture et Société (INRS) in Montréal, where I will be involved in a multidisciplinary research group (Tryspaces) and I will receive theoretical and technical training; b) a secondment in Institut de Govern i Politiques Publiques (UAB), in Barcelona, where I will pursue training activities; c) a return period in Centre Max Weber (Université Lyon 2), in Lyon, where I will transfer the acquired skills and develop additional training to enhance my career prospects. My profile being based on comparative politics and social movement sociology, the GF will provide me with a new interdisciplinary expertise in urban studies, critical geography and audio-visual and multimedia techniques, as well as a deep knowledge of international research funding procedures and research-leading skills ready to be used in France.

Keywords: social movement outcomes,urban displacement,neighbourhood mobilisations,oral history
The Fall of Acre and the Lamentation of Biblical and Ancient Cities in Medieval Literature and Historiography. (CITYFALL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2024-03-31
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: SIGNED

The fall of a city captivates the imagination, provokes intense emotional reactions and is often used to draw a line in historical narratives. The global attention and media coverage which the destruction of Mosul, Aleppo, or Palmyra have attracted during the ongoing war in Syria demonstrates the continuing power of the motif. Since antiquity the fall of cities has been lamented in different genres of writing and used to create historiographical thresholds. Prominent examples include biblical cities such as Jericho, Babylon or Jerusalem and ancient cities such as Troy, Carthage or Rome. This project aims to understand the role these ancient and biblical narratives played in the shaping of medieval political and cultural identities across transalpine Europe, reassessing the underestimated yet crucial role these biblical and ancient narratives played as they migrated into medieval Europe. Despite an increased interest in city laments in recent scholarship these studies remain mostly anchored in their original ancient or mediterranean contexts. The reception of these traditions in Western and Central Europe and most importantly the German lands remains unexplored, despite the fact that for over a thousand years, recourse to fallen cities provided the most inuential foil for narratives of political authority and legitimacy and also to make sense of present political occurrences such as the re-conquest of the city of Acre – the last outpost of the crusaders in the Eastern Mediterranen – to the Mamluks in 1291. Using the fall of Acre as a medieval starting point I will take a synchronous and daichronous look at medieval texts written between late 11th and the early 14th century to examine 1) which ancient textual traditions of lament were available for medieval writers 2) how were they used to make sense of the present by re-purposing the past and 3) how medieval identities were constructed and contemporary concerns of political and cultural belonging negotiated.

Keywords: city studies,history of discourse,historiography
Silicon-Organic Hybrid Transceivers for Terabit/s Data Network (SCOOTER)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-05-01
End date: 2018-10-31
Duration (months): 18.0
Total project cost (EUR): 149875.0
EU funding (EUR): 149875.0
Participants: 1
Project status: CLOSED

Megatrends such as the Internet of Things (IoT), Industry-4.0 paradigms, and cloud-based service delivery are combining to push data-center infrastructures to their limits. This applies in particular to Ethernet-based communication networks within large data centers, which limit further scalability of computing power and storage capacity already today. Compact power-efficient transceiver concepts are key to overcome these bottlenecks. SCOOTER aims at what the Ethernet Alliance has recently classified as the “Holy Grail” of the Ethernet ecosystem: Transceivers that enable serial transmission of 100 Gbit/s data streams, while fulfilling the stringent requirements of small-form-factor-pluggable (SFP) packages. The project exploits the concept of silicon-organic hybrid (SOH) integration that combines the economics of large-scale silicon photonic integration with the exceptional performance of organic electro-optic (EO) materials. In a series of experimental demonstrations, we have proven the superior performance of SOH electro-optic modulators, both in terms of speed and power consumption. The SCOOTER transceiver concept is expected to hit a strongly growing multi-billion Euro market. The study aims at an in-depth analysis of market opportunities and competitive boundary conditions, the specification of technical product concepts, as well as the associated IP strategy and risk analysis. The project shall result in a comprehensive business plan that allows to raise funds for the next phase of commercialization through a start-up company. We expect that the envisaged transceivers will not only help to overcome the communication bottlenecks in today’s networks, but may also have transformative impact on the long-term Ethernet roadmap, enabling interface rates of 400 Gbit/s, 800 Gbit/s, 1 Tbit/s, and beyond.

Keywords: integrated photonics,silicon photonics,optical interconnects,data center,silicon organic hybrid,transceivers,ethernet
Dance of galaxies: testing General Relativity and alternatives using galaxy velocity fields (GalaxyDance)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Poland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-04
End date: 2019-09-03
Duration (months): 24.0
Total project cost (EUR): 146462.4
EU funding (EUR): 146462.4
Participants: 1
Project status: CLOSED

We propose to use information encoded in peculiar velocity statistics of galaxies in the Local Universe as well as observed redshift space distortions (RSD) of distant galaxies for rendering new and very precise constraints on the validity of General Relativity (GR) and competing theories of modified gravity (MG) on cosmological and intergalactic scales. The main objectives and deliverables of our proposed research programme are: -To obtain precise modeling of both GR and MOG signatures in galaxy velocity field; -To develop self-consistent models of RSD for a wide class of MOG models; -To study the systematic impact of baryonic physics on velocity and clustering observables; -To perform a robust comparison of the predicted and observed velocity and RSD signal; -To compare cosmological parameters estimated using separately both methods; We plan to conduct our studies on GR and MG by developing methods proposed by us in previous works. For this goal it is necessary to develop a self-consistent RSD theory for MG. We will put emphasis here on the construction of theoretical models for anisotropic 2-point statistics, that will in a precise way model relations between theoretical quantities and observed ones. As a complementary probe and an important consistency test we plan to model and measure from observations 2-point correlation statistics of radial components of galaxy peculiar velocities. Our project, aimed at using galaxy velocities to test GR and MG theories on cosmological scales, will produce significant and crucial research deliverables that are necessary to fully exploit the new possibilities that the rapidly approaching era of big cosmological data will offer.

Keywords: theory of gravity,peculiar velocities,redshift space distortions
EyeControl (eyecontrol)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Israel
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 2843250.0
EU funding (EUR): 1990275.0
Participants: 1
Project status: CLOSED

Today, there are more than 1.2 Million ALS and other “locked-in” patients who cannot move or speak (due to a stroke, neurological diseases, spinal injuries, etc.). Those patients have fully functioning cognitive abilities, but they are locked in their bodies. EyeFree Assisting Communication Ltd. (EyeFree) plans on disruption of the ALS and locked-in assistance devices by providing EyeControl, a wearable and simple to use communication device that offers the main required communication functionality for much less than the currently used devices (supplied mainly by Tobii). The leading communication devices today are screen based, controlled by eye gazing on a screen, therefore requiring long training and limiting the ability of the user to speak only when the patient is in front of the screen and the system is calibrated to the screen position! EyeControl was developed by founders related to ALS patients in order to change the reality of the “locked- in” patients by enabling any patient to communicate anytime, anywhere. The EyeControl follows the user eye movements using an infrared camera; the camera translates the movements of the pupil into a “joystick” and transmits them to a small computer that converts the movements into actions. With EyeControl, we don’t use a screen; instead we rely on audio feedback, so that the user hears what he wants to say instead of seeing it on a screen. The user has a bone conduction earphone that enables him to hear what he wants to say before transmitting it. The device enables three levels of communication ranging from a basic call for help to more complex participation in a full conversation. The device can also connect to a smart phone/tablet via Bluetooth. Additionally, it enables the user to hear his own language in his earphone and transmit through the speaker in another language. This ability allows the user to communicate with a care giver that may speak a different language.

Keywords: assistive technology,wearable,locked in
Using Bariatric Surgery to Discover Weight-Loss Independent Mechanisms Leading to the Reversal of Fatty Liver Disease (BARINAFLD)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Israel
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2018-11-01
End date: 2024-04-30
Duration (months): 66.0
Total project cost (EUR): 1499354.0
EU funding (EUR): 1499354.0
Participants: 1
Project status: SIGNED

Non-Alcoholic Fatty Liver Disease (NAFLD), a disease characterized by accumulation of lipid droplets in the liver, is the major precursor for liver failure and liver cancer, and constitutes a global health challenge. An estimated 25% of the adult population suffers from NAFLD, but no FDA approved drugs are available to treat this condition. Obesity is a major NAFLD risk factor and weight-loss improves disease severity in obese patients. Bariatric surgeries are an effective treatment for obesity when lifestyle modifications fail and often lead to improvement in NAFLD and type 2 diabetes. The overreaching objective of this proposal is to combine bariatric surgery in mice and humans with advanced molecular and computational analyses to discover novel, weight-loss independent mechanisms that lead to NAFLD alleviation, and harness them to treat NAFLD. In preliminary studies, I discovered that bariatric surgery clears lipid droplets from the livers of obese db/db mice without inducing weight-loss. Using metabolic and computational analysis, I found that bariatric surgery shifts hepatic gene expression and blood metabolome of post-bariatric patients to a new trajectory, distinct from lean or sick patients. Data analysis revealed the transcription factor Egr1 and one-carbon and choline metabolism to be key drivers of weight-loss independent effects of bariatric surgery. I will use two NAFLD mouse models that do not lose weight after bariatric surgery to characterize livers of mice post-surgery. Human patients do lose weight following surgery, therefore I will use computational methods to elucidate weight-independent pathways induced by surgery, by comparing livers of lean patients to those of NAFLD patients before and shortly after bariatric surgery. Candidate pathways will be studied by metabolic flux analysis and manipulated genetically, with the ultimate goal of reaching systems-levels understanding of NAFLD and identifying surgery-mimetic therapies for this disease.
Neurocognitive mechanisms of inhibitory control training and transfer effects in children (DEVBRAINTRAIN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-09-01
End date: 2023-09-30
Duration (months): 73.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Inhibitory control refers to the ability to control behavioural impulses and is critical for cognitive development. It has been traditionally thought of as a stable trait across the lifespan but recent insights from cognitive neuroscience show prolonged changes in brain regions that support inhibitory control indicating greater malleability than previously believed. Because childhood inhibitory control predicts well-being later in life this suggests exciting opportunities for enhancing inhibitory control. I build on highly promising pilot results and draw on a recent neurocognitive model of inhibitory control to test 1) if inhibitory control can be enhanced during childhood, 2) if this transfers onto other domains important for healthy psychological development such as prosocial- and patient decision-making and academic achievement and 3) which factors predict training success. Children aged 5 to 10 years will undergo 8 weeks of inhibitory control training, which is a critical duration for observing prolonged training effects and be compared to a group undergoing active sham-training of comparable stimuli and duration but without inhibition. I will assess training effects on the brain and look at transfer effects onto other domains such as other executive functions, prosocial- and patient decision-making and academic achievement, both immediately and 1 year after training. I expect training to 1) improve inhibitory control, 2) transfer onto performance on above-mentioned domains and 3) elicit neural changes indicating the effectiveness of training for re- and proactive control. I also expect that individual differences in inhibitory control ability and associated brain regions prior to training will predict training success. The proposed research has the potential to generate a new and ground-breaking framework on early malleability of inhibitory control with implications for interventions at the time point of greatest likely impact.

Keywords: child development,inhibitory control,training and transfer effects
Multiscale Fluid and Plasma Dynamics using Particles (MEDUSA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-01-01
End date: 2025-12-31
Duration (months): 60.0
Total project cost (EUR): 1446125.0
EU funding (EUR): 1446125.0
Participants: 1
Project status: SIGNED

In the last decades, non-equilibrium effects in fluid and plasma dynamics have become the major topic for the understanding of the physics behind many applications and important industrial fields. These applications include mirco- and nano-technologies along with plasma-based coating processes of nano device fabrication itself, where small dimensions lead to non-eq. effects. But the applications range right up to other key areas, e.g. re-entry flows and flows around satellites, where rarefied gas and high velocities cause non-equilibrium. Furthermore, continuing miniaturization and increase of process energies will lead to non-eq. effects within technologies in the near future e.g. micro- and nano-fabrication, next-generation lithography or various space systems such as electric propulsion or actively electrodynamically shielded re-entry. At the moment, non-eq. is still a perturbing phenomenon, because experimental measurements are complicated and simulation tools are only available for specialised problems due to the complexity. The objective is to progress toward particle-based multiscale methods for thermo-chemical non-eq. gas and plasma flows allowing for the first time simulations of the whole range of high-tech applications and maintaining the competitiveness of European future industry. As the availability of computational resources increases with decreasing prices, particle methods have become a novel attractive, accurate and elegant numerical tool. This project will connect competences in physics, mathematics, chemistry and computational science and extend the open-source code platform PICLas, resulting in a direct benefit for the simulation community. Finally, as a main contributor in the field of particle-based fluid dynamics and the main developer of PICLas, I am confident to establish these novel methods as the state-of-the-art in research and academia as well as to enable their utilization in industrial applications.

Keywords: non equilibrium flows,gas kinetics,plasma kinetics,stochastic particle methods