Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
CommerciaL Energy ARray for Widespread Acceleration of Tidal European Resources (CLEARWATER)

Framework: FP7 — Cooperation
Programme: Energy
Destination: Renewable electricity generation
Action type: Collaborative project
Countries involved: Denmark,United Kingdom,United Kingdom,Netherlands
Call:  (FP7-ENERGY-2012-2, 2012)
Start date: 2014-01-01
End date: 2018-12-31
Duration (months): 60.0
Total project cost (EUR): 22630102.2
EU funding (EUR): 7736317.0
Participants: 4
Project status: CLOSED

Our project consortium will design, build, install and operate an open ocean 4.5MW tidal energy farm in the Inner Sound in the Pentland Firth, off the Northern coast of Scotland. The project (“Clearwater”) will demonstrate the technical and economic feasibility of a multi-turbine tidal energy array, an essential step to catalyse development of commercial projects in the EU ocean energy industry. Project Clearwater provides a credible, robustly implemented transition from high cost single turbine demonstration deployments of marine turbines to economically viable multi-hundred turbine arrays in oceans and managed water assets across Europe and the wider global market. The consortium consists of, and is funded by: UK - Atlantis Operations (UK) Ltd. (“Atlantis”): open ocean tidal turbine technology (including operating the world’s first 1MW grid connected open ocean tidal turbine at the European Marine Energy Centre in Scotland in 2011); Edinburgh University (“UEDIN”): research institution (with significant focus on all aspects of ocean energy, from resource analysis, through to array modelling and commercialisation research). The Netherlands –Royal Haskoning (“RH”): engineering and environmental consultancy (having secured in excess of 2,000MW of offshore wind consents). Denmark – DHI Water & Environment (“DHI”): world leaders in tidal resource assessment and hydrographical modelling. The project, which will run from 2014-2018, will build on the AR-series open ocean tidal turbine system tested at EMEC to deliver a wide range of new innovations. Most importantly the project will provide a number of step changes that will catalyse the European marine industry: Generating a target of 10,000MWh of clean energy to the European grid; De-risking environmental consenting process through novel monitoring methodologies to provide a holistic approach to monitoring; improvements in future ocean energy farm efficiency; reduction of per MW costs by up to 20% vs. single unit via the application of advanced manufacturing processes.

Keywords: tidal energy,commercilisation,cost reduction,advanced manufacturing processes,streamlining environmental consenting,array modelling tool,3mw grid connected ocean energy farm,eastern scheldt
Smart Nanoplasmonics for Chemistry and Biology (SNCB)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2013-03-01
End date: 2017-02-28
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

This multidisciplinary proposal will utilize smart plasmonic concepts to solve intriguing biological and chemical problems. The plasmonic nanostructures will be arranged using biochemical linkers to provide sharp multipolar resonances which are highly sensitive to structural changes in space. The resulting plasmon rulers enable high-resolution plasmon spectroscopy and render possible optical detection of cellular activities and 3D dynamic behavior of bioentities. These smart plasmonic nanostructures will help to answer many profound questions in biochemistry that have eluded definite conclusions. These innovative concepts will pave the way towards a whole new era in research by bridging prosperous disciplines, plasmonics, physics, biology, and chemistry.

Keywords: p108 optics and quantum optics,p212 nanophysics,p303 nanochemistry,p314 physical chemistry of biological systems
Titan's Lakes: Croll-Milankovitch, Seasonal and Hydrologic Cycles (TITANSLAKES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2012-08-01
End date: 2016-07-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

A set of liquid hydrocarbon lakes and lake basins has been discovered in Titan's high latitudes. The lakes exhibit a dramatic hemispheric asymmetry; significant area fractions of the northern high latitudes are covered by lakes, while the same southern latitudes are largely devoid of such features. We consider the hypothesis and its consequences that in addition to known seasonal changes, the observed difference in lake distribution may be caused by an asymmetry in the seasons owing to the orbit. Due to Saturn's eccentricity, the instantaneous solar insolation received at Titan is asymmetric. The asymmetry drives a hemispheric difference in evaporation minus precipitation, and hence, in the accumulation of lakes on Titan's northern and southern surfaces. The effect is modulated by, and reverses with, dynamical variations in the orbit. In this picture, much like in Earth's climate and glacial cycles, the resulting vigorous hydrologic cycle has a period of tens of thousands of years. We seek to answer the following fundamental questions: 1. To what extent do Titan's varying orbital parameters control the long-term volatile transport and surface reservoirs? 2. How do Titan's lakes and seas respond to seasonal forcing? 3. What is the relative role of subsurface transport of methane and ethane? 4. What constraints and general properties may be derived in order to better understand Titan's overall climatologic and hydrologic evolution?

Keywords: v201 climatology and climate change
Quantum information and sensing schemes for trapped ions (IONQUANSENSE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Quantum metrology, part of the emerging field of quantum technologies, is an extremely promising field which uses quantum mechanics to realize high resolution measurements. This includes magnetometry, atomic clocks and measurements of weak classical forces to name a few examples. The most important challenge in quantum metrology is to decouple the quantum sensor from the environment while maintaining the coupling to the probe. The field of quantum metrology currently experiences an exponential improvement of e.g. the frequency accuracy of optical clocks and growing activity in magnetometry. Progress in this field has also been stimulated by the success in quantum information processing. A central role in the field of quantum information is held by the entanglement, which quantifies the quantum correlations between two qubits. A major challenge in creating entanglement is that interaction with the environment creates noise which tends to destroy it. The most important challenge in quantum information is therefore to decouple a quantum bit from the environment but at the same time maintain as strong a coupling as possible to the other quantum bits. At first sight these two requirements seem to be contradicting. However, the effort to solve this contradiction has created an extremely successful field of dynamical decoupling As it is evident that these two fields are intimately related, this research proposal aims to combine the theoretical knowledge from quantum information processing with the experimental capabilities of quantum metrology, in order to unleash the synergy between the two fields and to design and realize schemes for the benefit of both disciplines. The main results of IonQuanSense would be high fidelity quantum simulators, high sensitivity magnetometers and precise atomic clocks.

Keywords: quantum sensing,trapped ions,quantum information,quantum metrology
Magnetic Fields in Neutron Stars via Numerical Simulations (NSMAG)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2012-08-01
End date: 2016-07-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Neutron Stars (NSs) are what is left after a massive stars terminates its life in a Supernova Explosion. It was immediately evident the role of rotation and magnetic fields in characterizing their phenomenology. We now know several different class of NSs, whose peculiarities we think are due to their intrinsic magnetic properties. Strong magnetic fields play a crucial role in many high-energy astrophysical systems containing compact objects. Understanding, the role of magnetic field in NS, developing the tools necessary for its correct modeling, and being able to follow its dynamics, has important consequences in other astrophysical fields. This proposal aims to develop a research line on the physics involving strong magnetic fields in compact objects, and their role in powering high-energy astrophysical engines, through the use of state-of-the-art computational techniques for relativistic MHD. The planned research has a strong numerical focus, which should complement, and enhance the existing theoretical and observational strength points already in place, both within the host institution and its national and international partners. We also plan to make all tools and numerical algorithms that will be developed, available on-line with a dedicated web-site The complexity of the physics involved makes the study of magnetized NS both challenging for its complexity and interesting for its possible outcomes. Numerical tools and techniques are now mature enough thanks to the recent development of robust and reliable multidimensional numerical schemes for general relativistic MHD, to be applied to the investigation of these systems. I plan to construct fully consistent magnetized models of NS in General Relativity; to investigate the role of the Equation of State in conjunction with the magnetic field; to investigate the role of magnetic dissipation ad turbulent dynamo ; nd to the magnetosphere-interior relation.

Keywords: p301 astronomy - astrophysics and cosmology,p216 fluid dynamics (physics),p111 relativity
Detection of Biomarkers using Nanorods and Nanopore technologies (NANO4BIO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2012-09-01
End date: 2016-10-17
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The application for the FP7-PEOPLE-2012-CIG is to support a move and integration of a new academic moving to Loughborough University, UK to take up a position of Lecturer in Analytical Chemistry. The researcher to date has published 21 peer reviewed journals and has a current h-index of 9. The funding is to secure and facilitate the long term integration of the researcher building upon his years of research experience and his existing independent research which has already produced patent applications and publications. In moving to Loughborough the applicant will be positioned within a world renowned department active in the field of analytical chemistry and biomarkers detection. This research proposal outlines a new technique capable of screening biomarkers with the capability of working directly in biological samples. The benefits of monitoring biomarkers lie in their ability to reveal signs of disease before the onset of major symptoms. The proposed technique will involve synthesizing nanoparticles that will be functionalized with aptamers/ or antibodies. These functionalized particles will capture the biomarkers directly from solution resulting in particle aggregation, and in conjunction with a resistive pulse sensing technology, will allow the quick separation and detection of the analyte, creating a new diagnostic technology. The experimental details will deliver a single process capable of capturing the analyte as well as performing the initial sample purification and pre-concentration stage that screens multiple biomarkers for several diseases across a wide range of molecular weights and functionalities When combined with the support infrastructure in place at Loughborough, the award will deliver a world leading research group integrated into the EU, delivering a new diagnostic technique to enhance the European research portfolio.

Keywords: c102 nanochemistry,c101 physical chemistry,c106 analytical chemistry,c127 materials for sensors,c128 nanomaterials,p306 surface science
Dynamic regulation of cytokine signalling in lymphocytes during inflammation (DCS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Cytokines are key regulators of immune responses and inflammation. However, excessive pro-inflammatory cytokine stimulation promotes chronic inflammatory pathologies. Commonly used cytokine-neutralizing therapeutic drugs cause severe side effects and in some patients are not effective. We thus expect that study of the intracellular signalling triggered by cytokine stimulation will provide new, more selective and effective therapeutic targets. DCS will focus on human protein tyrosine phosphatases (PTP) and suppressors of cytokine signalling (SOCS), which are important regulators of immune cell function. Research on PTP is particularly relevant, due to the large number of these phosphatases expressed by lymphocytes and the unknown function of many of them in the cytokine signalling that affects lymphocyte activation in health and disease. Although intracellular phosphorylation levels are essential for normal lymphocyte activation while preventing disease, the significance of phosphorylated SOCS species in these processes is poorly understood, and the PTP that regulate their levels are unknown. We will thus initially determine PTP and SOCS expression profiles associated to rheumatoid arthritis (RA), as a model of an inflammatory disease. Once potential genes involved in the pathology are known, functional genomic approaches will be developed to screen PTP and SOCS for regulators of cytokine signalling during activation of T and NK cells, which are involved in inflammatory disease development. We will further screen PTP for regulators of SOCS phosphorylation to understand their role in lymphocyte activation. DCS will use advanced microspectroscopy techniques on live cells to study the molecular dynamics of cytokine signalling regulators at the T cell and NK cell immunological synapses. This dynamic local regulation is currently poorly understood, although it appears essential in determining lymphocyte differentiation and activation.

Keywords: l101 molecular biology and interactions,l302 cell biology and molecular transport mechanisms,l604 immunosignalling
New nanosized metal oxy-FLUOrides: tailored SYNthesis and Energy Storage (FLUOSYNES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2012-09-01
End date: 2016-08-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Metal fluorides display numerous fields of applications which have been boosted by the emergence of fluorine nanochemistry. This proposal aims to develop new synthesis method to prepare nanosized metal fluorides with an emphasize on the understanding of the crystal formation. This will allow a fine control of the chemical composition/structure as well as the morphology of the prepared solid which is to be used in electrochemical devices, notably Li- and Na-ion batteries. Furthermore, a mechanistic investigation of Li and Na storage capacity in such materials will be conducted through advanced physico-chemical characterizations tools (synchrotron, NMR, etc). Finally, in marge of fundamental studies, the final aim of this work is also to propose a battery prototype and to provide a scalable method to prepare new class of fluorinated materials for next generation of electrode materials having high energy density.

Keywords: metal fluorides,nanomaterial,energy storage.
Quantitative Large Scale Proteomics of Lysosomal Storage Disease (STORAGE PROTEOMICS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2012-08-01
End date: 2016-07-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Lysosomal storage diseases (LSD) are a group of ~ 50 genetic disorders, which mainly affect children. LSDs are clinically heterogeneous but are frequently dominated by progressive neurologic deterioration. Most patients pass away after years of lingering illness. In general, the molecular pathogenesis of LSDs is still poorly understood. To gain insight into disease mechanisms the project investigates cellular proteomic alterations sequentially induced by increasing lysosomal storage. In vivo and in vitro models of selected LSDs affecting the nervous system will be investigated. Whole cell proteomes, subcellular fractions and tissues will be analyzed using quantitative large scale mass spectrometry based proteomic techniques employing stable isotope labeling based multiplex quantification approaches (TMT, iTRAQ, SILAC) and tandem mass spectrometry on an Orbitrap Velos mass spectrometer. Three model systems focusing on glial and neuronal cells will be analyzed: a) in vitro differentiation of NG2 glia to oligodendrocytes under normal or sulfatide accumulating conditions as a model for metachromatic leukodystrophy (MLD); b) in vivo alterations occurring in the course of progressive demyelination in the peripheral nervous system of a mouse model of MLD c) a cell culture model in which consequences of increasing storage of ß-glucosylceramide in neurons will be examined as a model of Gaucher disease. Using the quantitative data, alterations in protein expression and phosphorylation will be identified, grouped and analyzed for up- and downstream interaction partners as well as biological processes they are involved in. This will be done for various levels of storage to understand the succession and possibly the hierarchy of events. These data will allow describing cellular consequences of lysosomal storage in a so far unprecedented way, will allow generating new working hypotheses, and may provide the basis for the identification of new therapeutic targets.

Keywords: lif,l203 proteomics,quantitative large scale mass spectrometry,l511 neurological disorders,lysosomal storage disease,gaucher disease,metachromatic leukodystrophy,lipid storage disorder
Model theoretic stability for Banach spaces (MODSTABBAN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2012-CIG, 2012)
Start date: 2013-06-01
End date: 2018-10-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 2
Project status: CLOSED

The proposed project will advance our knowledge in the field of model theory and its applications to functional analysis and Banach space geometry. The research will mobilize recently developed powerful model theoretic techniques in order to throw more light on important and basic questions in Banach space theory. The project will enhance exchange of ideas and techniques between different areas of mathematics, especially stability theory within model theory and Banach space theory. Specifically, we propose to explore connections between model theoretic stability and geometric structure of a fixed Banach space, as well as an elementary class of Banach spaces. The main idea is that stability leads to deeper understanding of spreading models in the ultra-powers of a structure. The project will continue and expand the work of Krivine and Maurey, who proved that stability implies the existence of an almost isometric copy of an l_p space. One of the questions we are going to address is whether weaker versions of stability entail the existence of isomorphic copies of basic sequence spaces. Another question that we will investigate has to do with the phenomenon of categoricity. A class of Banach spaces is called categorical if it has a unique structure (up to isometry) of some uncountable density. We have recently shown that any such class is strongly related to the class of Hilbert spaces, affirming a 35-year old Henson's Conjecture. Recent developments suggest stronger geometric forms of the conjecture, which we will address. In addition, we propose to investigate an analogous conjecture for categoricity under isomorphisms (instead of isometries), which is a much more challenging problem. However, given recent progress in "geometric stability theory" in the context of Banach spaces (due to the my collaborators and myself), we are confident that many interesting results are within reach now.

Keywords: m101 logic and foundations,m110 operator algebras and functional analysis