Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
MICSED - Molecular Interactions in Complex Systems (MICSED)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2014-02-01
End date: 2018-01-31
Duration (months): 48.0
Total project cost (EUR): 1467956.6
EU funding (EUR): 1467956.6
Participants: 2
Project status: CLOSED

This proposal brings together Procter and Gamble (the world’s largest producer of packaged consumer goods), with Durham University (a world top-50 science faculty in a research-intensive university) to train ESRs capable of bringing market-changing research innovations to a wide range of product areas. Modern consumer products have to be highly sophisticated to achieve the performance levels consumers demand, and often have to be significantly over-engineered to deliver acceptable levels of reliability and stability. This can lead to significant sustainability issues. Product innovations enabling the reduction of active ingredients, better performance with lower consumer energy consumption and lower post-usage waste will have significant impact. The simultaneous requirement for stability in storage and efficacy during usage requires product formulations to be remarkably complex multi-component multi-phase systems with many interacting molecular species. Transformative innovations can therefore only be achieved through molecular-level insight, understanding and control. The Molecular Interactions in Complex Systems European Industrial Doctorate (MICSED) will provide the theoretical tools, molecular scale experimental probes and mechanistic understanding required to achieve real insight and predictive ability. The toolkits it provides will enable sustainable innovations in Hygiene, Laundry and Personal Care products. The new insights into underlying molecular interactions and the capability to quantitatively predict how systems behave have potential to enable disruptive innovation and paradigm-changing new sustainable technology platforms which can be reapplied well beyond P&G’s fast moving consumer market. MICSED will showcase Europe as a centre for industry-academia partnership working. With P&G serving 4.5 billion of the world’s 7 billion consumers the potential for economic and environmental impact is significant.

Keywords: formulation science phase behaviour consumer products
Hit to lead optimisation of novel anti-TB scaffolds through an academic-industrial partnership (COOPERA-TB)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Spain
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2014-02-01
End date: 2018-01-31
Duration (months): 48.0
Total project cost (EUR): 1174366.0
EU funding (EUR): 1174366.0
Participants: 2
Project status: CLOSED

We propose a PhD programme for 4 Early-Stage Researchers (ESR) in tuberculosis (TB) drug discovery. Often associated with poverty, TB is rampant in many parts of Africa and Asia but has now also returned to developed nations. Growing resistance against currently used antibiotics is one of the most pressing problems of the global TB epidemic. Treating TB infections requires a drug cocktail given for at least 6 months, extending to 2 years for infections with multi-drug resistant strains of Mycobacterium tuberculosis, the agent causing TB. A largely successful campaign by the WHO to stem the global rise of TB has not diminished the urgent need for new and better drugs and cellular targets to alleviate the devastating impact of this disease. In this project, we will train 2 biochemists/biologists and 2 chemists in TB drug discovery, initially, for 18 months at the University of Birmingham, UK, followed by 18 months at the Tres Cantos campus of GSK DDW (Diseases of the Developing World) in Madrid, Spain. Upon successful completion of the programme, the ESRs will be awarded PhD degree titles by the University of Birmingham. In their individual, yet interconnected, research projects, the 4 ESRs will work on the hit-to-lead optimisation of inhibitors of 2 novel drug targets, M. tuberculosis DprE1 and QcrB, building on preliminary work done at Birmingham in collaboration with GSK DDW. The guiding principle of this joint academic-industrial PhD programme is to provide ESRs with a comprehensive perspective on the drug discovery process. By the time they graduate, they will not only have acquired in-depth knowledge of drug discovery and optimisation, but will also have made significant research contributions to a globally relevant disease area. Finally, through their exposure to both academic and industrial research environments, the ESRs can be expected to become effective advocates for future knowledge transfer and collaboration between academia and industry within Europe.

Keywords: young researchers training,industrial doctorates,drug discovery,knowledge transfer,tuberculosis,new chemical entities,microbiology,medicinal chemistry,structural biology,hts
A new concept in zeolite catalysis: Morphology induced shape selectivity (ZEOMORPH)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Norway,Denmark
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2013-09-01
End date: 2017-08-31
Duration (months): 48.0
Total project cost (EUR): 1523231.6
EU funding (EUR): 1523231.6
Participants: 2
Project status: CLOSED

Zeolites are crystalline aluminosilicates and have been used as catalysts within refining and hydrocarbon conversion processes since the 1960s. In addition to possessing strong Brønsted acidity, zeolites are microporous materials, having regular pores channels and cavities of molecular dimensions. These materials therefore possess shape selectivity for chemical reactions. Nevertheless, insufficiently shape selective catalyst, leading to rapid deactivation and unselective production, is a major obstacle for improved and new zeolite based industrial processes. The scientific vision of ZeoMorph is to establish a new concept within shape selective zeolite catalysis - morphology induced shape selectivity, wherein the shape selective properties will be determined primarily by particle morphology and not framework topology. The concept will be demonstrated by synthesis of series of catalysts having systematic morphological properties, which will be examined as catalysts in industrially relevant hydrocarbon conversion processes. This ambitious vision will be met by bringing together leading European groups within physical and inorganic chemistry. The catalysis research group at the University of Oslo (UiO) in Norway and Danish industrial partner Haldor Topsøe (HTAS) based in Lyngby near Copenhagen are full network participants. Research groups at the University of Torino (UniTo, Italy) and Aarhus (AU, Denmark) with unique competence within spectroscopy and computational chemistry will be associated partners in the project. The ZeoMorph early stage researchers will spend 50% of their time in the industrial sector at HTAS and the remaining time will be divided between extended stays at the partner academic host UiO and 3 month stays at the associated partners. This network will educate 5 ph.d. candidates with unique multi-faceted emphasis on world leading basic research, industrial innovation and entrepreneurship.

Keywords: c102 nanochemistry,c112 catalysis,c114 chemical reactions,c119 structural properties of materials,c124 porous materials,c128 nanomaterials,c136 homogeneous and heterogeneous catalysis
Sources, Interaction with Matter, Detection and Analysis of Low Energy Electrons 2 (SIMDALEE2)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria,United Kingdom,Italy,Czechia,Switzerland,Netherlands,Greece,Germany,Slovenia,United Kingdom,Germany
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2014-09-01
End date: 2018-08-31
Duration (months): 48.0
Total project cost (EUR): 3399600.45
EU funding (EUR): 3399600.45
Participants: 12
Project status: CLOSED

The purpose of the SIMDALEE2 (Sources, Interaction with Matter, Detection and Analysis of Low Energy Electrons) network is to establish a world-class research training platform for the science and technology of nanoscale manipulation and analysis using low energy electrons. Apart from an effective and well-structured training programme, the network will pursue the following scientific goals: (1) optimizing beam size by correlating contemporary field emission (FE) theory with high resolution holographic measurements of magnetic and electric fields of FE tips with different shapes, both with and without primary electron optics; (2) putting the understanding of the contrast mechanism of electron beam techniques on a sound footing by comparing physical models with novel benchmark spectra acquired using a coincidence technique; (3) improving detection as well as understanding of emitted energy-, angular-, and spin-dependent spectra. This issue will be addressed for the common case of detectors in the a field-free environment, and for the special case when the emitted electrons encounter an electric field prior to detection; (4) Electron beam modification of nanostructured surfaces; (5) Progress in the aforementioned fields will lead to the development of an innovative prototypical methodology for nanoscale characterization with electron beams in the form of a compact desktop-type Near-Field-Emission Scanning Electron Microscope (NFESEM). Finally, (6) the economic impact and feasibility of low energy electron beam methodology will be investigated within the project. Accordingly, the ESRs and ERs will develop and acquire experience on a comprehensive methodology beneficial for any industrial or academic laboratory employing or developing electron beam techniques for natural science studies, as well as for biology and engineering. Their participation in this interdisciplinary and intersectoral network will greatly further their career opprtunities in S&T in Europe.
Small Artery Remodelling (SMARTER)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,Germany,Germany,Denmark,Sweden,Switzerland,Hungary,Germany,United Kingdom,Netherlands
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2013-11-01
End date: 2018-01-31
Duration (months): 51.0
Total project cost (EUR): 3911347.0
EU funding (EUR): 3911347.0
Participants: 11
Project status: CLOSED

Cardiovascular disease remains a major cause of morbidity and mortality in Europe. Small arteries form a key element in the pathogenesis. Thus, these vessels dictate local perfusion and blood pressure by adaptation of their caliber. Structural changes towards smaller caliber, small artery remodelling, cause hypertension and decreased organ perfusion, leading to acute events and chronic end organ dysfunction. Despite this role, these vessels are poorly studied and therapeutic options based on these arteries are lacking. SmArteR (Small Artery Remodelling) collects 13 academic and SME partners who have set up a training programme for 12 ESRs and 3 ERs. We address the interaction between cells, extracellular matrix and mechanical loading in an integrative way, taking advantage of the multidisciplinary partnership. Thus, we will unravel the processes in small artery remodelling at the molecular, cellular and integrative physiology level, and we will develop novel and marketable technology aimed at studying these vessels in vitro under the right biomechanical conditions. The ESRs and ERs are trained in not only cardiovascular R&D, but also in a range of skills required to form the new generation of frontrunners in biomedical research in academia and industry.

Keywords: vascular remodelling microcirculation hypertension
Quantifying Uncertainty in Integrated Catchment Studies (QUICS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,Netherlands,Netherlands,Germany,Portugal,Luxembourg,Switzerland,United Kingdom
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2014-06-01
End date: 2018-05-31
Duration (months): 48.0
Total project cost (EUR): 4058233.86
EU funding (EUR): 4058233.86
Participants: 10
Project status: CLOSED

The Water Framework Directive (WFD) is the most significant EU legislation concerning surface water management. Programs of Measures are required to ensure water bodies achieve a good ecological status. It is important to predict the impact of interventions on water quality. Man-made and natural processes control surface water quality, these are highly complex with a range of sources, transport and transformation processes. Cost estimates by EU governments indicate that billions of euros will be spent over several decades to implement WFD. There is an increasing level of concern on the implementation cost (financial and carbon). Integrated water quality models designed to predict the quality of water across the linked urban and rural scales in a catchment is seen as a tool to optimise this cost. Integrated Catchment Modelling (ICM) is based on linking numerous empirically calibrated sub-models of water quality processes. Catchment scale WQ predictions are then used to justify investment. Current water quality sub-models contain significant uncertainty. Methods have been developed to quantify uncertainty at a level however little work has been carried out to investigate WQ uncertainty propagation between sub-models. QUICS will develop a generalised catchment wide approach to uncertainty assessment that can then be used in WFD implementation studies. It will address uncertainty propagation at the spatial and temporal scales found in catchments and develop tools to reduce uncertainty by optimising sampling and monitoring and the objective selection of model structure. This will reduce uncertainty in WQ predictions and result in better informed investment decisions and so have a significant impact on WFD implementation. QUICS contains leading water quality scientists, uncertainty experts and private sector water management practitioners and modellers. It will train researchers capable of developing and implementing uncertainty management tools into ICM studies.

Keywords: water framework directive,water quality modelling,pollution,catchments,uncertainty,decision making
Novel Complex Metal Hydrides for Efficient and Compact Storage of Renewable Energy as Hydrogen and Electricity (ECOSTORE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Norway,Denmark,Italy,France,United Kingdom,Switzerland,Germany,Greece,Germany,France,Germany
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2013-10-01
End date: 2017-12-31
Duration (months): 51.0
Total project cost (EUR): 4051541.94
EU funding (EUR): 4051541.94
Participants: 12
Project status: CLOSED

Finding novel solutions for energy storage is of high societal relevance, since it is a prerequisite for the turnaround from fossil fuels and nuclear power to energy from renewable sources, since these sources mostly are intermittent. Also for providing an ecological friendly mobility, high capacity energy storage solutions are urgently needed. Well trained experts in energy storage are a prerequisite of the necessary technological development. ECOSTORE contributes to these targets by training 12 ESRs and 3 ERs in materials science and use of novel metal hydrides for energy storage – chemical, as hydrogen, and electrochemical, in batteries. The fellows will be trained in scientific skills by pursuing own research projects (leading to a PhD in the case of ESR) as well as in complementary skills, important for their future career in academia or industry, like management of scientific and technical projects, science-public communication and development of their own career and personality. ECOSTORE is an international network of partners each with high reputation in the field of hydrogen and electrochemical storage. 9 European research institutions, 3 European industrial companies, and 2 Associated Partners from Japanese Universities form a network of complementary scientific and techno-economical expertise. Novel borohydride- and nitride based materials may allow for high energy storage densities in terms of both hydrogen and electrochemical processes. For commercial introduction, a prerequisite is the cost efficient large scale production from abundant and relatively cheap raw materials, going from extremely pure chemicals and laboratory-scale to less pure raw materials and industrial scale. ECOSTORE aims at the scientific understanding of materials behaviour in hydrogen as well as in electrochemical processes, and, based on this, at scale-up of cost effective materials production, and at prototype testing to perform a techno-economical evaluation of the developments

Keywords: energy storage,materials,hydrogen storage tanks,batteries,reaction mechanisms,diffusion,ionic conductivity,thermodynamics,kinetics,in situ methods,materials modelling,materials processing
Sustainable Biomass Conversions by Highly Efficient Catalytic Processes (SUBICAT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Netherlands,Germany,Netherlands,Finland,Netherlands,Netherlands
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2013-10-01
End date: 2017-09-30
Duration (months): 48.0
Total project cost (EUR): 3943849.69
EU funding (EUR): 3943849.69
Participants: 7
Project status: CLOSED

The goal of a sustainable society requires the efficient use of renewable or sustainable materials and demands the development of selective new methodologies for the preparation of desirable products. In this context we require: (i) a change from traditional stoichiometric, high energy methods that produce huge amounts of chemical waste to mild and clean catalytic processes and (ii) a major step change in chemicals production with fossil fuels being replaced by renewable resources as chemical starter units. In this proposal we have identified a series of collaborative projects that would benefit from the mutual exchange of scientific expertise between several European academic and industrial partners. This collaboration will provide new links within the EU to be established in order to train a new generation of scientists to deliver research excellence in the challenging change from fossil to renewable resources. The challenge to change our societies reliance for chemical production from fossil-fuel based to all-renewable resources is a challenge of enormous scale.This change must be broken down into smaller, manageable components capable of demonstrating the effectiveness of this strategy in order to showcase the transition necessary. In this proposal we will establish links with world leading experts to develop leading examples of this approach and have identified several areas where we believe collaboration can impact. Using the complementary multidisciplinary expertise from the network partners we will: Develop optimal catalysts for ether cleavage in 'real life samples' of lignin for maximising the potential of lignocellulose as a source of fuels and fine chemicals. The most successful catalyst systems developed will be immobilized using advanced fluids and these systems will be fully explored and optimised through collaboration within this ITN consortium.
Ecohydrological interfaces as critical hotspots for transformations of ecosystem exchange fluxes and biogeochemical cycling (INTERFACES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,France,Slovenia,Spain,Germany,Austria,Germany,Luxembourg,Spain,United Kingdom
Call:  (FP7-PEOPLE-2013-ITN, 2013)
Start date: 2013-11-01
End date: 2017-10-31
Duration (months): 48.0
Total project cost (EUR): 3787007.18
EU funding (EUR): 3787007.18
Participants: 13
Project status: CLOSED

INTERFACES is a supra-disciplinary training and research network that aims (1) to develop conceptual process understanding of the role of ecohydrological interfaces (i.e. system boundaries) for the transport and transformation of fluxes of heat, energy and water and interlinked biogeochemical cycles (C, N, O) at micro- to landscape-scale; and (2) to create the next generation of supra-disciplinary scientist that are able to work beyond traditional disciplinary boundaries, blend cutting-edge field, laboratory and modelling technologies, and understand the practical relevance of their research. Ecohydrological interfaces connect different environmental (sub-) systems and represent important new cross-disciplinary research domains to extend our knowledge horizons. Moreover, these environmental intersections offer an extremely fertile training ground because exploration of interface process dynamics requires novel linkage between traditionally distinct disciplines, and development of a supra-disciplinary research and training philosophy to foster the evolution of a new generation of scientists. Training and research will span novel distributed sensing technologies, innovative tracer methods and integrated numerical models of heat fluxes, metabolism, biogeochemical turnover and ecological functioning to understand how, when (hot moments) and why ecohydrological interfaces (e.g. aquatic-terrestrial, groundwater-surface water, marine-sediment interfaces) act as critical hotspots for water-dependent environmental processes. The urgently improved mechanistic process understanding developed by INTERFACES will not only provide industries, regulators and decision makers with the capacity to predict the complex, non-linear landscape-wide impacts of ecohydrological interfaces in a changing environment but also to understand how important ecosystem services provided by different ecohydrological interfaces can maintain or even enhance resilience to global environmental changes.

Keywords: ecohydrology,ecosystem interfaces,supra-disciplinarity,distributed sensor networks