Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Complex dynamic interactions of nonlinear, multistage and localization phenomena in turbine engines: development and validation of efficient and accurate modeling techniques. (UPGRADE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2011-IOF, 2011)
Start date: 2012-09-16
End date: 2015-03-15
Duration (months): 30.0
Total project cost (EUR): 307291.45
EU funding (EUR): 307291.45
Participants: 1
Project status: CLOSED

Current and next-generation turbine engines will increasingly depend on onboard health monitoring and prognosis systems to help ensure the reliability, safety, and readiness of air vehicles. To effectively interpret the measurement data required for monitoring and prognosis of turbine engines, efficient reduced models that show to capture the essential complex dynamic interactions of nonlinear, multistage, and localization phenomena must be employed. In the research project, advanced structural dynamic models and experimental validations will be developed for turbine engine rotors. The main goals of the proposed research are: • To model and predict the nonlinear vibration response of a rotor with cracked blades or blades damaged by a foreign object, including accounting for random mistuning and multistage coupling. • To provide a fundamental physical understanding of localization phenomena in rotors due to individual and combined effects of mistuning and foreign object damage and/or cracks. • To identify localization phenomena and nonlinear vibration characteristics strongly associated with cracks to exploit them for structural health monitoring and damage detection. Although structural health monitoring tools will not be developed directly in this research, the work will help describe and understand the fundamental nonlinear structural dynamics so that the proposed modeling technologies can be used in health monitoring and prognosis applications. During the project, the fellow will acquire new competencies and skills in the field of non-linear modeling of cracked bladed disks and multi-stage modeling techniques of bladed disks, strengthening his academic profile in the field of modeling techniques and structural health monitoring of turbine engine. The fellowship will impact on the career development of the fellow and on the European excellence and competitiveness due to the novel technical competencies that will be developed and transferred to the EU.

Keywords: turbo-machinery (aero-engine technologies),aerospace engineering,vibration engineering,simulation engineering
Extended Subtractive Synthesis of Audio Signals (ESUS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Finland
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-04-01
End date: 2014-03-31
Duration (months): 24.0
Total project cost (EUR): 201877.8
EU funding (EUR): 201877.8
Participants: 1
Project status: CLOSED

The purpose of this proposal is to generalize the subtractive sound synthesis method for digital audio applications. Whereas the basic idea of Additive Synthesis consists in adding the sinusoidal components of a Fourier series, the analog Subtractive Synthesis aims to imitate a given periodic sound by filtering a fixed excitation signal (usually square, triangle or sawtooth signals). With this source-filter principle, the spectral envelope is reproduced by designing the filter. For some decades, the Additive Synthesis has been significantly improved for computer applications, but the Subtractive Synthesis not. Actually, on one hand, the recent digital subtractive synthesizers focus on modelling old analog synthesizers since the 1960s (from which the Moog is the most popular), and on the other hand, the source-filter principle has been improved for the particular case of the speech coding and synthesis only. Here, we plan to apply recent advances of the audio processing field to derive a new Extended Subtractive Synthesis method. For example, we will study the use of time-varying filters and pitch trajectories to reproduce transients, modulations and roughness. With learning from recorded sounds, we will estimate the parameter trajectories. Moreover, we will use knowledge about psychoacoustics to imitate the original sound from a perceptual viewpoint. This new synthesis technique will have applications in sound synthesis of harmonic musical sounds, and we plan also to synthesize animal sounds. The new method will also be useful for computer game audio. Moreover, most of usages of current Additive Synthesis could be applied, such as time or frequency stretching or noise removal. The main benefits of the Subtractive Synthesis are the reduced number of parameters and the easier control of the resynthesis.

Keywords: electrical engineering,sound engineering. audio signal processing,analysis and synthesis of sounds,musical instruments,acoustics
Emerging Protist Parasites of Frogs: Global prevalence and host/parasite interaction (PARAFROGS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-09-01
End date: 2015-02-28
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 2
Project status: CLOSED

The causes of global decline of amphibian population is still unclear, however it is apparent that this animal group is susceptible to opportunistic infections. Two important infectious agents have been identified: a fungus and a virus, both of which are responsible for mass mortalities. However, since 2003, new mass mortality events have been recorded through out the USA and have been attributed to infection by a protist of the Superphylum Alveolata. This parasite preferentially infects liver tissue leading to the presence of hundred of thousand small spherical cells. In parallel, environmental sequencing of freshwater environments targeting the smallest size of eukaryotic plankton has revealed that this group of protists is globally distributed and has a free-living stage. We have performed a pilot test on 28 tadpoles specimens from the collection of the Natural History Museum of London (UK) in order to confirm the association between the protist and frogs and found three positive cases in distantly related frog taxa. We therefore hypothesise that this protist group represents a global threat to frogs and has a complex lifecycle involving both infectious and freeliving phases and has acquired cellular phenotypes and molecular innovations associated with host infection. Using a combination of molecular pathology of global tadpole samples, microscopy with cell biological staining, and comparative transcriptomics this project will identify the geographic and taxonomic prevalence of this pathogen and how and by what molecular mechanism it infects tadpole cells. As such the project will underpin advanced training in: collection management, histology, immuno-microscopy, comparative genomics and microbial parasitology of animal hosts. This project will provide information important for understanding the diversity of microbial eukaryotic forms, evolution of parasitic mechanisms and understanding disease threats to frogs in order to assists conservation planning.

Keywords: natural sciences,biodiversity,molecular parasitology,disease and conservation,alveolates
Lyapunov Analysis in the COaSTal Environment (LACOSTE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-09-01
End date: 2014-08-31
Duration (months): 24.0
Total project cost (EUR): 193594.8
EU funding (EUR): 193594.8
Participants: 1
Project status: CLOSED

Coastal regions provide a wide range of resources and services, and thus represent an essential environment for human activities. However, coastal areas are rapidly degrading under the pressure of anthropogenic activities and climate change. Hence a correct management of the ecological resources of coastal regions is vital for a sustainable development. A correct management can not be achieved without understanding the mechanisms which regulate and control horizontal transport and cross-shelf exchanges. These processes play an important role in regulating the ecological and biogeochemical conditions of coastal regions. In recent years, Lagrangian techniques, like the Finite Size Lyapunov Exponent (FSLE) method, have become increasingly important for the analysis of horizontal mixing and transport in the oceans. FSLE can be used to identify Lagrangian Coherent Structures (LCSs) which provide direct information on transport and mixing patterns of a flow. The LACOSTE project will focus on the analysis of LCSs in the Gulf of Lion (GoL, Northwestern Mediterranean) in order to characterize the transport patterns from both numerical model results and altimetry derived velocity fields. A region-specific processing procedure for along-track altimetry measurements will be developed in order to obtain more accurate altimetry derived velocity fields in the GoL. LCS analysis will be integrated with two other new techniques: Self Organizing Maps (SOM) will be used to identify the dominant transport patterns and their temporal variability; the PHYSAT algorithm will be applied to remote sensed optical measurements to assess the ecological impact of the detected transport structures and to investigate the underlying physical-biogeochemical interactions. The LACOSTE project will allow to identify the areas most impacted by the dominant transport patterns, providing an essential contribution for the development of a sustainable management of the ecological resources of the GoL.

Keywords: coastal physical oceanography,interdisciplinary study,lagrangian coherent structures,ocean modeling,satellite altimetry,in-situ observations,som,physat,ocean ecology,coastal ocean management
Settlement and spatial dynamics along the Appian way, between the Suburbium and the city of Rome (SASDAPPIA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2013-04-01
End date: 2015-03-31
Duration (months): 24.0
Total project cost (EUR): 193726.8
EU funding (EUR): 193726.8
Participants: 1
Project status: CLOSED

This research investigates the construction, the evolution and the development of settlement spaces from the Republican to the Late Antique times in the area of the city of Rome, which is characterized by the extra-mural passage of the Appian way. It seeks to expand our knowledge of the critical area that delineates the passage between the urban and the suburban spaces of the ancient city. Its principal object is the contextual analysis of the suburban territory of the via Appia with the aim to reconstruct, in a diachronic way, the settlement dynamics that could attest the active spatial relationships between the urban and the suburban area. An important secondary goal is to define the functional zoning of this area and the changes in the use of places, outlining how historical artefacts can relate to new spatial programs. More generally, this is an investigation into the ways in which structures and places and their internal components were spatially organised. Within the study of spaces, the project explores the nexus of social, political and economic flows with the result of assessing the interaction and integration of the city and its hinterland. To achieve these goals, the project focuses on all ambiguous connections between the places that are located in the critical area between the urban and the suburban spaces. Among these places, an archaeological site will be chosen as a case study of the phenomenon: the systematic analysis of its spatial and social connections with the whole area and in a diachronic way will enable us to reconstruct the settlement dynamics of the territory through time. The project is thus based on two principal spatial domains of data: geographic, territorial or macro-scale data and monumental or micro-scale data. A holistic approach has been chosen for this investigation and visualization of the whole area, and a monographic approach has been selected for querying and visualizing the case study.

Keywords: archaeology,information systems,topography,anthropology,human geography,architecture,sociology,3 d modelling,database management,ancient history
Tuning of the mechanical and electronic properties of graphene by strain, chemical doping and defects (MESCD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-07-30
End date: 2014-07-29
Duration (months): 24.0
Total project cost (EUR): 177000.0
EU funding (EUR): 177000.0
Participants: 1
Project status: CLOSED

The mechanical properties of graphene, the thinnest material in the world, will be investigated theoretically. This project will focus on the basic and advanced mechanical properties that are potentially useful for controlling: i) the strain distribution, ii) the band gap, and iii) the observation and visualization of electronic polarization in single/multilayer graphene. The theoretical approaches will be based on large scale classical atomistic simulations and density functional theory methods. An essential part of the proposal is the transfer of knowledge to the host organisation by means of research on very timely topics. The candidate will provide hands on knowledge transfer on state of the art Molecular Dynamics simulation method for obtaining thermo-mechanical properties of large scale graphene flakes, electronic band structure calculations of nanostructured and chemically modified graphene flakes, Quantum Monte Carlo calculations for studying many electron graphene quantum dots, and providing the required input data for tight-binding calculations.

Keywords: mechanical and thermal properties,graphene,chemical doping,defects,band gap,strain nanoengineering,solid state physics
Computer-aided Design and synthesis of inhibitors of EED-EZH2 interaction as a novel approach for anticancer therapy (HKMTIS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2013-04-03
End date: 2015-04-02
Duration (months): 24.0
Total project cost (EUR): 209033.4
EU funding (EUR): 209033.4
Participants: 1
Project status: CLOSED

The Polycomb repressive complex (PRC2) complex catalyzes the trimethylation of lysine 27 on histone H3 (H3K27me3), which is an important epigenetic mark for maintaining transcriptional repression. The interaction between the two of the components, EED and EZH2, of PRC2 is essential for the required histone lysine methyltransferase (HKMTase) activity that resides in the SET-domain of EZH2. We propose to design the inhibitors of EED-EZH2 interaction using the recently reported X-ray crystal structure of the complex and employing computational drug design methods. A stepwise rational approach will be employed that would involve, identifying a binding sites around the important amino acid residues of EED, structure-based pharmacophore generation, virtual screening, structure optimization and biological screening, in order to discovery the novel HKMTase inhibitors

Keywords: pharmaceutical chemistry,computational chemistry,organic chemistry
Neutrino Oscillations in Dense Medium: Probing Particle Physics together with Astrophysics and Cosmology (DENSE NEUTRINOS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2013-04-01
End date: 2015-03-31
Duration (months): 24.0
Total project cost (EUR): 174475.2
EU funding (EUR): 174475.2
Participants: 1
Project status: CLOSED

Neutrinos are the most elusive of all elementary particles and play a crucial role in astrophysics and cosmology. The three different kinds (flavors) of neutrinos can convert into each other, a macroscopic quantum effect, by their flavor mixing. These "flavor oscillations" are strongly modified by the feeble refractive impact of matter, a conspiracy between the very small neutrino masses and their very weak interactions. In dense astrophysical environments, notably core-collapse supernovas and the early universe, neutrinos themselves exert a refractive effect on each other, causing nonlinear feedback effects. These "collective" or "nonlinear" flavor conversions have been the subject of intense theoretical study over the past few years because they can strongly affect the neutrino signal from the next galactic supernova and flavor oscillations in the early universe. They are also of purely theoretical interest, being described by the equivalent of the pairing Hamiltonian that describes superconductivity and correlation effects in nuclei. This project ventures to develop the theory of collective flavor oscillations and applications in supernovas and the early universe to a new level of understanding. The puzzling complications caused by the lack of isotropy of the neutrinos streaming from supernovas ("multi-angle effects") will be scrutinized with analytic and numerical techniques. The existence and importance of new instabilities will be investigated. The impact of nonstandard interactions will be included and the signatures in large-scale neutrino observatories will be studied. Furthermore, the project aims at applying these insights to the early universe where, in particular, the oscillation into yet unobserved "sterile neutrinos" can change the cosmic radiation and hot dark matter content.

Keywords: quantum field theory,astrophysics,cosmology,neutrinos,supernova,neutrino oscillations
Linear and cyclic double-strand molecular wires (TWO-STRAND)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-03-01
End date: 2014-02-28
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 1
Project status: CLOSED

This project will focus on double-strand nanowires and nanorings consisting of butadiyne-linked porphyrin oligomers. One objective is to create double-strand linear conjugated polymers with useful nonlinear optical properties for ultrafast all-optical communication systems. Another objective is to explore a new approach to template-directed synthesis, whereby one nanoring acts as a template to direct the construction of a second complementary nanoring. Double-strand porphyrin nanorings are of high interest because of their resemblance to photosynthetic light-harvesting complexes. They are also expected to have interesting nonlinear optical properties. Professor Anderson is a leading expert in supramolecular chemistry and the engineering of molecular wires. The Department of Chemistry at Oxford is one of the top chemistry departments in Europe with outstanding research facilities. Christiane Knappke recently completed her PhD at the University of Cologne in the field of N-heterocyclic carbene chemistry. During her PhD work, she synthesised some remarkable electron-rich pi-systems. This experience made her eager to learn about the synthesis and characterisation of larger functional pi-systems. Anderson’s group provides an ideal environment for gaining this expertise. This project will provide her with high-level hands-on training in supramolecular chemistry, template-directed synthesis, electrochemistry, photophysical techniques and EPR spectroscopy. She has the necessary expertise to make fast progress with the project, and to rapidly acquire new skills. This fellowship will put her in a very strong position to start an independent research career. The project includes collaborations with physical chemists, physcicists and materials scientists, located in Oxford and other EU-countries. The fellow will be fully engaged with these collaborations. This contact will add a valuable dimension to the training while increasing the scientific impact of the project.

Keywords: organic chemistry,supramolecular,molecular wires,porphyrins,extended conjugated pi-systems,template-directed synthesis
Children and War: Resilience Beyond Programmes (CAWRBP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-10-01
End date: 2014-09-30
Duration (months): 24.0
Total project cost (EUR): 209033.4
EU funding (EUR): 209033.4
Participants: 1
Project status: CLOSED

The aim of this fellowship is to develop an integrated theoretical social (re)integration framework for children born of war and their ex-combatant mothers in light of the unique but extreme challenges faced by these children in contemporary African armed conflicts. Five objectives will be pursued, namely; 1. Identify and analyse the situation of “(re)integrated” ex-combatants and their children born out of forced pregnancies and rape by enemy soldiers in post conflict northern Uganda; 2. Identify and analyse the situation of “(re)integrated” ex-combatants and their children in post conflict countries of East Timor, Bosnia-Herzegovina and the Democratic Republic of Congo (DRC); 3. Compare social (re)integration policies and practices associated with study communities in Northern Uganda, East Timor, Bosnia-Herzegovina and the DRC; 4. Apply findings to the existent theoretical framework and thus revise and make more effective the social (re)integration approaches to benefit ex-combatants and the children born of war; 5. Participate in international discussions and contribute to building scholarship for improvement of social (re)integration policies and practices globally. Tasks will be accomplished in five phases, namely; preparatory; extensive and elaborate comparative analysis of study communities; in-depth analyses of social (re)integration policies and practices; development of alternative framework(s) for social (re)integration of children born of war and their ex-combatant mothers and the return phase to enable the emerging framework be tested on study communities in Oyam and Otuke districts in northern Uganda and thus, inform further refinement of the framework.

Keywords: social sciences,children and war,disarmament,demobilisation,born of war,reintegration and integration,post (re)integration challenges