Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Immune DIREcted and Cancer-selective immunoTherapy (I-DireCT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Germany,Israel,Czechia,Netherlands
Call: Innovative Training Networks (H2020-MSCA-ITN-2018, 2018)
Start date: 2019-01-01
End date: 2023-09-30
Duration (months): 57.0
Total project cost (EUR): 2532975.22
EU funding (EUR): 2532975.2199999997
Participants: 5
Project status: SIGNED

I-DireCT is a European Industrial Doctorate (EID) training network designed to provide training and carry out breakthrough research on the rapidly expanding and high impact field of cancer immunotherapy in a carefully integrated academic and inter-sectoral programme. Hereby, we aim to develop next-generation immunotherapeutics and deliver a set of early stage researchers uniquely qualified for a career in academia and/or industry. Current immunomodulatory antibodies that target pivotal immune checkpoints have revolutionized the field of oncology. However, off-tumor activity limits their application. The objective of I-Direct is to address this issue by 1. developing innovative bispecific antibodies and immunocytokines with tumor-restricted immunostimulatory effects and 2. developing optimized delivery systems to ensure optimal timed release of bio-active drug. Hereto, I-DireCT combines state-of-the-art industrial design of nanotech-based drug formulations with innovative academic and industrial immunotherapeutic concepts into the next-generation of cancer immunotherapeutics. At the core of I-DireCT is its training objective to offer a cutting-edge multidisciplinary training programme that will enable outstanding young scientists to generate breakthrough ideas and assume leading positions in academia and industry. This training programme includes an array of disciplines, ranging from biomedical sciences (e.g. immunology, antibody engineering) and physical sciences (e.g. chemistry, material science) to drug design & development. Industrial partners are central to the programme and provide pivotal inter-sectoral expertise on how to translate scientific discoveries into commercial reality, with each ESR being appointed at an inter-sectoral partner for 18 months, as well as through additional secondments. Further, I-Direct will enable long-term multi-disciplinary research and fosters bilateral co-operations between academia and industry.

Keywords: antibody based immunotherapy,nanoparticle drug formulations,cancer micro environement,checkpoint,co stimulation,selectivity
Towards a more efficient exploitation of on-shore and urban wind energy resources (zEPHYR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Argentina,Greece,Belgium,Poland,Belgium,France,Netherlands,Netherlands,Netherlands,United Kingdom,Denmark
Call: Innovative Training Networks (H2020-MSCA-ITN-2019, 2019)
Start date: 2019-11-01
End date: 2023-10-31
Duration (months): 48.0
Total project cost (EUR): 3778737.66
EU funding (EUR): 3778737.66
Participants: 13
Project status: SIGNED

The rise of a low-carbon society, compatible with economic growth and environmental sustainability, is pending on a number of technological evolutions and breakthroughs. In that line, the role played by wind energy is deemed to increase further in the next decades. The development of performant wind farms is pending upon the performance of each turbine composing the wind farm, and on the optimal harvesting of the local wind resources. A wind park performance is nowadays predicted assuming standard profiles of mean incoming velocity, turbulence intensities and scales, etc. corresponding to standard terrain topographies and atmospheric conditions. One main limitation of such standards is that the assumed flow and turbulence properties were established to fit databases gathered on a limited number of locations, which are by definition not representative of the quite various terrain configurations nor local micro-meteorological situations that can be met in practice. This is a concern for complex terrains and is furthermore hampering the implementation of wind turbines in urban environments, which constitutes nevertheless an important component of future environmentally-friendly Smart Cities thanks to the favorable local flow accelerations, pressure build-up, canyon effects, etc. offered by an urban canopy. The ambition of this multi-disciplinary training platform is the development and application of advanced meso/microscale atmospheric models and the assessment of the impact of real terrain and local atmospheric effects on the predicted aerodynamic performance, structural dynamics and noise emissions. Obviously, human factors become a critical issue when considering implementing wind turbines in densely populated urban environments. The inter-dependencies between those factors (visual vs. acoustic effects, age or occupation, etc.), which complicate further the analysis of the motivations for a community to endorse or reject a new project, will be addressed as well.

Keywords: horizontal axis wind turbine,vertical axis wind turbine,diffuser augmented wind turbine,building integrated wind turbine,aeroacoustics,aeroelasticity,human factors,optimization,flow control
An innovative digital crowdsourced platform to foster soft skills development to boost Europe’s productivity and economic growth. (QDOOZ)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: United Kingdom
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-09-01
End date: 2019-02-28
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Exponential changes brought by rapid technological advances mean soft skills such as creativity, problem-solving, leadership, team work and emotional intelligence are becoming more important than traditional hard skills. According to CBRE, 50% of occupations today will no longer exist in 2025 with new jobs requiring higher levels of soft skills. However, data from the European Commission estimates that more than 70 million Europeans lack essential soft skills, causing Europe to lose as much as €112 billion per year due to reduced productivity. Traditional solutions such as education largely focus on developing technical, ‘hard’ skills while complementary solutions such as mentoring are prohibitively expensive. Other solutions such as e-learning platforms (LinkedIn Mentoring, Quora and StackExchange) do not provide the means to assess and measure soft skills development which is crucial to track progress and prove competence. In response to this, a team of highly renowned mentors and software engineers has developed QDOOZ – an innovative digital platform that contains the proprietary Soft Skills Framework, Multi-Approach Assessment Model and Soft Skills Profile which enable us to uniquely develop, assess and measure soft skills to successfully demonstrate progress, attainment and competence. We have formed a commercial partnership with UCAS, the UK’s higher-education admission service, to allow end-user testing and we have gathered enormous support from numerous businesses and Governments who have shown great interest in our product. We now need to reduce commercial risk by running large scale trials and optimising our product performance prior to global roll-out. 5 years post-project, we will generate annual revenues of €59.5 million, €36.3 million in profits, 275 jobs, representing a 20 x ROI to EC investment whilst potentially adding €4 billion to Europe’s economy, leading to higher productivity gains and significantly improving Europeans’ quality of life.

Keywords: content crowdsourcing,on demand digital platform,soft skills development,soft skills assessment models,soft skills gap,digital advertising,mentoring
Researchers in the Knowledge Triangle (K-TRIO 2)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Bulgaria,Bulgaria,Bulgaria,Bulgaria,Bulgaria,United Kingdom
Call: European Researchers' Night (NIGHT) (H2020-MSCA-NIGHT-2014, 2014)
Start date: 2014-06-01
End date: 2015-11-30
Duration (months): 18.0
Total project cost (EUR): 248645.0
EU funding (EUR): 201000.0
Participants: 8
Project status: CLOSED

The K-TRIO 2 consortium organized in several years Researchers’ Night in Bulgaria in different cities making people and especially children and youth aware of researchers’ profession and the contribution of research to economy and society. The public opinion surveys show that the Researchers’ Night became a popular event in many Bulgarian cities. People enjoy the variety of activities offered and would like to make the Researchers’ Night a regular “Fall rendez-vous” in their city with a lot of fun and interaction with researchers. Taking into account the objectives of the Researchers’ Night initiative of the EC, and the previous experience of the consortium, the project K-TRIO 2 sets as its main goal to enhance public recognition of researchers and innovators and their role in society and to encourage young people in Bulgaria to embark on research career. In the framework of the Europe 2020 strategy, the project focuses on the need for increasing the number of researchers and innovators in Europe and to foster the interest of the society and the youth, in particular, to research and innovation. For achieving the main goal, the following project objectives are defined:  to disclose to the public the hidden sides of life and work of researchers, and show them as professionals and ordinary people;  to highlight the EU emphasis on its researchers, the role of researchers in the Knowledge triangle and for building the Innovation Union;  to involve citizens in debates on the contribution of researchers to European economy and society, as well as in ideas generation and open innovation;  to foster active citizens position on the policy for growing research talents and making research and innovation attractive for young people. The target audience of the project will be on first place young people – children, teen-agers and students, and secondly – their parents and the public at large. The project K-TRIO 2 will provide various opportunities to citizens in Bulgaria to meet and entertain with researchers.

Keywords: reserachers night events
The Role of Physiology in the Causes and Consequences of Fisheries-Induced Evolution (PHYSFISH)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-05-01
End date: 2020-10-31
Duration (months): 66.0
Total project cost (EUR): 1499880.0
EU funding (EUR): 1499880.0
Participants: 1
Project status: CLOSED

There is increasing evidence that intense commercial fishing pressure is not only depleting fish stocks but also causing evolutionary changes to fish populations with serious consequences for the viability of marine fish communities. Although current research on fisheries-induced evolution (FIE) has focused almost exclusively on the effects of size-selective harvest on reproductive potential of wild populations, there are a range of traits besides body size which could also affect the selectivity of fishing gears but which have not been investigated. For example, overlooked within the context of FIE is the likelihood that, within a given species, variation in physiological traits among individuals – and especially those related to energy balance (e.g. metabolic rate) and swimming performance (e.g. aerobic scope) – could make some fish more catchable or more likely to suffer mortality after discard. Selection on these traits could produce major shifts in the fundamental structure and function of fish in response to fishing pressure that are yet to be considered but which could directly determine population resource requirements, resiliency, geographic distributions, and responses to environmental change. This pioneering project will combine innovative approaches in the laboratory with cutting-edge acoustic tracking technology in the field to address this gap in knowledge with three main goals: (1) to examine whether physiological traits make some individuals more catchable by commercial fishing gears, and whether the environment modulates such effects; (2) to investigate the extent to which physiological traits influence recovery and survival after escape from fishing gear or discard; and (3) to determine whether selection on catchability generates changes in physiological traits that reduce population resiliency or erode the ability to cope with environmental change. Given that several fisheries have not recovered despite lengthy moratoriums, there is a pressing nee

Keywords: physiology,ecophysiology,behaviour,fish,evolution,conservation physiology,metabolic rate,aerobic scope
The EU Smart Building Innovation Platform (SMARTBUILT4EU)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Italy,Belgium,Finland,Poland,Belgium,France,Netherlands,United Kingdom,Luxembourg
Call: Support to the coordination of European smart buildings innovation community (H2020-LC-SC3-EE-2020-1, 2020)
Start date: 2020-10-01
End date: 2023-03-31
Duration (months): 30.0
Total project cost (EUR): 1495250.0
EU funding (EUR): 1495250.0
Participants: 11
Project status: CLOSED

The building sector is one of the key enablers to achieve low carbon economy goals for 2050. To deliver this potential, buildings need to transform from passive isolated elements to smart buildings, able to adapt to occupants needs and act as active nodes well integrated to the energy grids and other infrastructures. The 2018 revised Energy Performance of Buildings Directive (EPBD) promotes the use of ICT and smart technology in buildings to streamline the existing rules. Smart technologies indeed play an essential role and can also trigger new business opportunities. However the market uptake and wide-scale roll-out of these solutions is slow due to challenges like engaging building occupants, connecting and managing various devices and systems, achieving optimal building operation, integrating buildings to energy markets, as well as the high fragmentation of the ecosystem. These challenges are common to projects related to the smart building topic and would be most efficiently addressed by breaking silos, sharing information and bridging the gaps between innovation, markets and policy. SmartBuilt4EU will consolidate the Smart Building Innovation Community with, at its core, EU-funded projects, and provide it with a package of supporting activities with two objectives: - facilitate the exchange of information between EU-funded projects and national initiatives in the field of smart buildings and the related business, policy and media; - coordinate contributions of the Smart Buildings Innovation Community to the SRI promotion, experimentation and implementation and the identification of R&I priorities to accelerate the roll out of smart building innovation, in line with the EPBD. The CSA brings together 5 partners plus 5 linked third parties, with solid complementary expertise and geographical coverage. It is structured in 6 work packages to reach the targeted impacts and unlock the smart building potential, with the Smart Readiness Indicator as key instrument.

Keywords: smart building innovation community,smart readiness indicator
MERIL-2 MAPPING OF THE EUROPEAN RESEARCH INFRASTRUCTURE LANDSCAPE (MERIL-2)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Support and infrastructures
Action type: Coordination and support actions
Countries involved: Italy,Greece,France
Call: Policy measures for research infrastructures (H2020-INFRASUPP-2014-2, 2014)
Start date: 2016-03-01
End date: 2019-08-31
Duration (months): 42.0
Total project cost (EUR): 1951092.0
EU funding (EUR): 1951092.0
Participants: 3
Project status: CLOSED

The MERIL-2 project aims to create an authoritative, exhaustive online source of scientific and policy relevant data on European research infrastructures (RIs) of more than national relevance. It addresses the work programme priorities of promoting the development and coordination of policy and international cooperation in the domain of RIs. MERIL-2 builds on the successful development of the original MERIL and research mapping exercise initiated by the ESF membership and which services ESFRI. MERIL-2 aims to achieve step changes in terms of: 1) The comprehensiveness of RIs identified in the portal from 900 to 1200+ and the full publication of those identified from 500 to 800; 2) The utility of the portal in terms of functionalities, analytical capacity and intermediation; 3) Stakeholder value in terms of policy relevant data including financial and human resource dimensions and coverage of RI mapping processes and tools in comparator regions. These objectives will be met through a synergistic partnership of three organisations; European Science Foundation (ESF), the Greek National Documentation Centre (EKT-NHRF) and Agency for the Promotion of Research (APRE), that harnesses the complementary strengths of advanced portal design, European member state communication systems and deep knowledge of the RI landscape and data acquisition requirements under the leadership of an expert advisory committee. On a practical level, the approach will include redesign of the portal with enhanced functionalities, expert/ESFRI and NDI consultations on policy data needs and parameters, a complementary review of RI data policies and strategies and policies including implications of policy data provision and resourcing a publishing completion function for non-responsive RIs. These actions will lead to an enhanced MERIL-2 portal with comprehensive coverage of the European RI landscape and high quality systems and data of stakeholder interest with flexible, open and user oriented interfaces.

Keywords: meril,research infrastructures,portal,europe,mapping,data,more than national relevance,international research infrastructure linkages
Experimental determination of the paraxial-vectorial limit of light-matter interactions (LIGHTMATT-EXPLORER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

The aim of this proposal is to study the transition between the scalar an vectorial regimes of light-matter interactions and show that its knowledge can be used to create a chirality-discriminating device. For that, the scalar-vectorial transition will be studied for three conceptually different nanostructures. The study will be carried out with a technique developed by the ER: vortex beam-induced circular dichroism. The findings of the study will be given by means of three look-up-tables, one for each kind of nanostructure. These look-up-tables will allow any light-scientist working with similar nanostructures to identify the regime (scalar/vectorial) in which their light-matter interactions are taking place. The results of this project will improve our fundamental understanding of light-matter interactions. This knowledge will add a new dimension into the characterization of complex 2D and 3D nanostructures. To show the potential of this characterization, at the end of the project we will use the look-up-table of a 3D plasmonic vortex to design a device that efficiently discriminates the chirality of molecules. The project has all the ideal elements to fulfill its goals. On one hand, the ER is already a scientific expert in light-matter interactions at the nanoscale. On the other hand, the Plasmon Nanotechnologies group at IIT, with its world-class laboratories and clean rooms provides an extraordinary scientific environment for the ER to develop his career path. In particular, it is expected that the ER learns many different nanofabrication techniques. Thus, thanks to this action, the ER will become a preeminent scientist with a unique set of skills combining nanofabrication, optical manipulation/measurements and simulations/theoretical work. This will place him in an advantageous position to become a world leader in nano-optics. The supervision and expertise of Dr. De Angelis will ensure that these goals are reached.

Keywords: vortex beams,circular dichroism,chirality,non paraxial,nanofabrication