Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Pathways to survival in a hotter world (HotLife)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental B iology, Ecology  and E volution
Panel description: For all organisms : Ecology, biodiversity, environmental change , evolutionary biology, behavioural ecology, microbial ecology , marine biology, ecophysiology, theoretical developments and mod elling
Countries involved: Sweden
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-05-01
End date: 2030-04-30
Duration (months): 60.0
Total project cost (EUR): 1999966.0
EU funding (EUR): 1999966.0
Participants: 1
Project status: SIGNED

Global warming and heatwaves – hallmarks of climate change that are expected to worsen in the 21st century – diminish reproductive success and cause excess mortality in wild and domesticated animal populations. Yet, we still have sub-standard knowledge of almost all fundamental traits that medi-ate success or failure under climate change, and, for most animals, there are no data on the extent to which plasticity, local adaptation, or evolutionary change can alleviate the stress imposed by a hotter world. Collectively, therefore, the research field is at status quo. To mitigate this situation, HotLife will leverage my previous phenomenological studies on ontogenetic priming and plasticity of thermoregulatory capacity to generate novel knowledge on when and why animals fail in the heat, and whether plastic or evolutionary responses may render failure a less likely outcome in the future. The main outcomes of HotLife will reveal: 1) How heat tolerance manifests, how much it can evolve, and whether plasticity halts evolutionary rescue; 2) Whether climate warming and climatic extremes directly or indirectly cuts life expectancy short; and 3) If the physiological basis for heat tolerance is inherited in the wild and if it is already being selected upon I will achieve these ambitious goals by combining state-of-the-art thermal and sub-cellular physiology with intricate genomic techniques and powerful heritability analyses in captive and wild bird models – the endotherm group for which heat-induced mass mortality is most frequently reported. HotLife goes beyond the state-of-the-art, by i) bridging crucial knowledge gaps between heat failure in birds, its physiological basis, and its links to fitness and survival; ii) addressing the potential for rescue by plasticity or evolution from these effects; and iii) uncovering evidence for local adaptation and heritability of heat tolerance in the wild.

Keywords: bird,cross fostering,evaporative cooling,evolutionary change,extreme weather,global warming,heat stress,heat dissipation,heat shock protein,local adaptation,metabolic rate,mitochondria,population decline,thermoregulation,transgenerational plasticity
Restoring a normal life and dignity for women and men suffering from severe Stress Urinary Incontinence (UroAct)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2023-07-01
End date: 2024-12-31
Duration (months): 18.0
Total project cost (EUR): 13161839.5
EU funding (EUR): 2499999.0
Participants: 1
Project status: CLOSED

Severe stress urinary incontinence affects hundreds of millions of women and men in the world. It is an ignored public health problem, as it is often hidden. For those who suffer from it, it turns their lives into a living hell. Existing solutions are unsatisfactory. For men, manual artificial urinary sphincters (AUS), require the scrotum to be manipulated for each voiding, sometimes with the help of a relative for dependent people. It's humiliating. These devices, are associated with a significant rate of revision and explantation, notably because of manually manipulated implantable components and the constant pressure exerted on the urethra often leading to erosion and atrophy. The patient is plunged back into the hell of incontinence for good. For women, the most commonly used solution is mesh sling, initially developed for cases of prolapse. This solution leaves 15% of women incontinent, with a further 5% suffering serious, irreversible damage. To such an extent that they are the subject of over 100,000 lawsuits in the USA. Women are left without a safe, convenient and effective solution. Severe incontinent people urgently need a safe and decent solution. We are developing the first smart artificial urinary sphincter, designed to solve all the drawbacks of current devices. UroActive™ is: - connected: voiding is done by remote control or by gently tapping on the abdomen (no more genitals manipulation) - self-adjusting: the occlusive pressure is automatically adjusted depending on patient's position and activity - personalized: the surgeon can wirelessly adjust device parameters after implantation - secure: if the patient cannot control the device or loses consciousness, the device automatically opens to prevent overpressure in the bladder and kidney injury. UroActive™ will provide an efficient, reliable, easy to use and safe solution to minimise the risk of side effects and gives their lives and dignity back to patients

Keywords: urology,stress urinary incontinence,artificial urinary sphincter,active implantable medical device
CONQUERING NEW STRATEGIES TO PREVENT AND REDUCE PACKAGING POLLUTION (MAGNO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Clean Environment and zero pollution
Action type: Research and Innovation actions
Countries involved: Spain,Portugal,Germany,Italy,Belgium,Tunisia,Lebanon
Call: Strategies to prevent and reduce plastic packaging pollution from the food system (HORIZON-CL6-2023-ZEROPOLLUTION-01, 2023)
Start date: 2024-01-01
End date: 2027-06-30
Duration (months): 42.0
Total project cost (EUR): 3999963.75
EU funding (EUR): 3999963.75
Participants: 12
Project status: SIGNED

As Europe shifts to a bio-based circular economy, a plethora of new packaging restrictions have emerged. MAGNO seeks to improve packaging effectiveness, sustainability, efficient usage, end-of-life (reuse and recycling), and innovative business practices in EU food systems through revolutionary strategies shaped for the ecological transition required by the European Green Deal and EU 2030 climate target plan. These strategies will strengthen the EU food and packaging policy frameworks at a local and regional level. They will also increase social innovation, consumer participation and acceptance of new packaging designs and production models in cross-border food value chains through a web platform and a series of citizen science tools. At the beginning of the project, an overview of Europe’s ecosystems and value chains for different kinds of plastic packaging will be studied. A detailed quantification of impacts and solutions in terms of health, environment, raw materials, and sustainability will then be developed to set the basis of an Ecosystem Digital Twin software. The Digital Twin will be programmed to support the analysis of different scenarios which contributes by not only providing ground-breaking strategies for improving the packaging sector but also identifying the best options in terms of innovative business. The whole project will be supported by the active participation of food multi-actors (researchers, food business operators, food packaging producers, developers of sustainable packaging, packaging converters and recyclers, consumers, and local and regional authorities). Their contribution to the creation of results and validation of the final strategies will prevent and reduce plastic packaging pollution for the food and packaging sectors.

Keywords: ecosystem digital twin,consumer acceptance,waste management,bio plastics,health,environment protection
Developing sustainable solutions for viticulture through multi-actor innovation targeting breeding for integrated pest management (GrapeBreed4IPM)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Research and Innovation actions
Countries involved: France,Germany,Italy,Spain,Austria,Serbia,Switzerland
Call: Biodiversity friendly practices in agriculture – breeding for Integrated Pest Management (IPM) (HORIZON-CL6-2023-BIODIV-01, 2023)
Start date: 2024-04-01
End date: 2028-03-31
Duration (months): 48.0
Total project cost (EUR): 5000000.0
EU funding (EUR): 5000000.0
Participants: 21
Project status: SIGNED

According to the World Economic Forum and the European Union’s Biodiversity Strategy for 2030, biodiversity loss and ecosystem collapse are major threats facing humanity in the next decade. Massive consumption of chemical pesticides in agriculture is a significant contributing factor. Viticulture ranks high among the crops that depend on a massive consumption of chemical pesticides, consuming approximately sixty percent of the fungicides applied in the EU, making it a priority target for reducing the use of chemical plant protection products. At the same time, grapevine is economically and culturally important in the EU, with wine and wine-based products being among the top 3 EU agri-food sectors. Recent advances and new perspectives in grapevine breeding have opened the possibility for GrapeBreed4IPM to address the reduction of fungicides and preserve biodiversity. Lessons learned from past experience in viticulture have shown that success in improving sustainability relies on global involvement of all actors. Therefore, we brought together the top European research groups in grapevine breeding and involved different stakeholders along the grapevine industry value chain in a multi-actor and co-design approach to produce the best insights for maximum impact. The project will develop grapevine varieties with resistance to relevant diseases, adapted to local environmental and pedoclimatic conditions, and with the goal of reducing reliance on chemical pesticides. In addition, the project will provide farmers, winegrowers and advisers with best practices and guidelines for integrated pest management, adapted to disease-resistant varieties, as ingredients for their largest possible adoption and leading to a long-awaited more environmentally friendly and sustainable viticulture in Europe. The project’s outcomes will support evolution of the grapevine market to meet regulatory requirements and consumer expectations, a market that is expected to reach nearly EUR 204 billion by 2025.

Keywords: co design,multi actor,grapevine,disease resistance,downy and powdery mildew,black rot,botrytis bunch rot,participatory breeding,conventional and organic farming,sustainability,piwi,terroir
Predicting functional DIVErsity of INvasive freshwater plants (DIVE IN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy,Canada,Brazil
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-08-01
End date: 2027-07-31
Duration (months): 36.0
Total project cost (EUR): 256442.88
EU funding (EUR): 256442.88
Participants: 3
Project status: SIGNED

Biodiversity is facing the imperative challenge posed by invasive species responsible for substantial damage to habitat integrity and ecosystem services. Freshwaters are particularly susceptible to invasions, and this is causing a dramatic decline of the irreplaceable services they provide. This project aims at untangling the mechanisms underlying invasion performance by determining and predicting the spatial range of functional variation of three highly invasive freshwater plants (Elodea nuttallii, Pistia stratiotes and Trapa natans) in response to environmental conditions, thereby obtaining better estimates of their influence on the functioning of invaded habitats. This global MSCA is outlined in 36 months and includes 24 months at McGill University, Canada, under the supervision of Prof. L. Iversen, an outstanding scientific leader in the field of landscape geography and freshwater science, and 12 months at the University of Parma, Italy, with supervisor Dr. R. Bolpagni, a renowned expert on freshwater plants. I will measure leaf functional traits of target species across ecological gradients and describe strong trait-environment relationships in Europe and Québec. I will also perform manipulative experiments to validate and implement spatial models of trait variation. Training through research will be combined with courses on spatial modelling, science communication, and project management. DIVE IN provides a robust framework that can be applied to different invasive plants and global change scenarios, supporting the development of effective actions to counter invasive freshwater plants establishment/success. DIVE IN’s impact will be maximized by publishing papers in high-quality scientific journals, as well as by public engagement activities, including a blog, workshops, and citizen science initiatives. This project is a key step in my future career and will grant me a unique training opportunity, opening doors to prestigious research positions in Europe.

Keywords: functional traits,macrophytes,invasive species,spatial modelling
Geography and Cartography in Dante's «Comedy» (GEODETIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-08-01
End date: 2026-07-31
Duration (months): 36.0
Total project cost (EUR): 288859.2
EU funding (EUR): 288859.2
Participants: 3
Project status: SIGNED

The GEODETIC project aims to explore an understudied and undervalued aspect of Dante’s poem: the geography of our world. Alongside its imaginary afterlife sceneries, the Comedy shows fourteenth-century Italian and European geographies, most of which are still recognizable today. Dante outlines an unprecedented, detailed, and exact image of the world, but above all he reveals profound geographical awareness. The very few studies on this theme are obsolete or weak at exegetical level. An updated analysis is therefore needed, integrating a philological approach with the territorial data through a specifically interdisciplinary methodology. The project firstly proposes a complete examination of the Italian and European geographical areas described in the «Comedy», along with of those in the «De vulgari eloquentia». Secondly, a specific focusing on a selection of places is foreseen, aiming for the geo-historical reconstruction of the physical territories mentioned by the poet through relevant geographic, historiographic, literary, and iconographic sources. Web mapping services will be also fundamental to localize and visualize each of the geographical elements considered. The first objective is to investigate the components of Dante’s geographical culture. The second objective is to evaluate his geographical knowledge in its own environmental framework, in order to enrich our comprehension of his poetry and shed light on passages, whose correct interpretation depends on a clear understanding of topographical details. The third objective is to verify the possible presence of maps among Dante’s sources by matching his text to extant cartographic documents. The recent progress made in medieval cartography and the increasing digital accessibility of this heritage will be crucial to advancing my analysis. The result will open up an innovative perspective on Dante’s geo-poetics as an essential constituent of the poem.

Keywords: dante studies,medieval and italian studies,landscape studies,history of geography,history of cartography
BREEDING AND INTEGRATED PEST MANAGEMENT STRATEGIES TO REDUCE RELIANCE ON CHEMICAL PESTICIDES IN GRAPEVINE (SHIELD4GRAPE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Research and Innovation actions
Countries involved: Italy,Greece,Spain,Portugal,France,Hungary
Call: Biodiversity friendly practices in agriculture – breeding for Integrated Pest Management (IPM) (HORIZON-CL6-2023-BIODIV-01, 2023)
Start date: 2024-02-01
End date: 2027-01-31
Duration (months): 36.0
Total project cost (EUR): 4697312.5
EU funding (EUR): 4697312.5
Participants: 18
Project status: SIGNED

Climate change and environmental degradation have been challenging Europe and the whole world. The EU biodiversity strategy for 2030 is a comprehensive, ambitious and long-term plan to preserve nature and reverse the ecosystem degradation. Grapevine (Vitis spp.) is one of the major fruit crops worldwide, and although viticulture is a leading sector of the EU agro-industrial economy, it is the cropping system with the highest use of agrochemicals and with a high risk of biodiversity loss. SHIELD4GRAPE (S4G) will adopt sustainable agroecological approaches addressed to improve the resilience of the viticultural system against pest diseases in a context of climate change. The S4G consortium brings together the best excellences in the sector; it is multi- and interdisciplinary, collaborative and well representative of different EU biogeographical regions. S4G will i) exploit grapevine biodiversity and identify new resilience traits; ii) implement breeding activities, including new breeding techniques and mutagenesis, iii) introduce safer and more sustainable strategies against pathogens. Demonstration fields will be set up in all the most important EU regions interested in viticulture to improve the efficacy of applied integrated pest management protocols in combination with the new resilient genotypes. S4G aims to support farmers and researchers, to provide advisory services and actors in value chains by establishing an interrelated community that will facilitate exchange of knowledge and of the best practices at different levels and socio-economic resilience. S4G impacts will add value to the wine heritage of the EU regions by reducing chemical treatments (at least by 50%), using strategies that are less hazardous to the environment and favouring beneficial organisms. S4G will contribute to safeguard the territory (particularly those areas with a high concentration of vineyards), human health, farmers, the population living in grape-growing areas and consumers

Keywords: grapevine,germplasm biodiversity,new plant breeding techniques,marker assisted breeding,somaclonal variation,synthetic microbial communities
Direct seawater electrolysis technology for distributed hydrogen production (SWEETHY)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Research and Innovation actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: Sweden,Italy,Spain,Germany,France,Norway,Netherlands
Call: Development of innovative technologies for direct seawater electrolysis (HORIZON-JTI-CLEANH2-2024, 2024)
Start date: 2025-03-01
End date: 2029-02-28
Duration (months): 48.0
Total project cost (EUR): 4429293.78
EU funding (EUR): 3999768.04
Participants: 9
Project status: SIGNED

SWEETHY will develop an advanced technology for direct seawater electrolysis that will be able to produce H2 and O2 under intermittent conditions accounting for the coupling to renewable power sources (especially wind, PV). The electrolyser will be based on an anion exchange membrane (AEM) operating in natural or alkaline seawater, and the SWEETHY technology will be developed along three dimensions: a) Materials optimization to meet the specific requirement of seawater environment: A focus will be made on corrosion resistance and selective PGM-free electrocatalysts for hydrogen and oxygen evolution reactions, on AEM with high selectivity for transporting hydroxide anions and anti-fouling properties as well as on novel anti-corrosion coatings for bipolar plates and porous transport layers prepared by plasma spraying and electrodeposition. b) An electrolyser stack prototype based on a novel stack architecture applying hydraulic cell compression is developed to host the advanced materials to produce H2 at high pressure. Beneficial functions of the targeted unique stack are related to scalability and maintainability that will be tremendously improved in comparison to conventional AEMWE stacks. c) Sustainability analysis studies not only for the electrolyser system but also for its integration into renewable-power systems and for efficient by-product utilization in industrial symbioses, feeding back to materials optimization and stack development early on. Complementing LCA, social LCA and techno-economic analyses/optimization by qualitative work ensures both environmental, economic, and social sustainability. Combining these three dimensions, SWEETHY will utilize Mediterranean seawater feed in Messina, Italy, to withstand more than 2000 h of operation to produce 20 gH2/h with a degradation rate lower than 1%/100h. In addition, SWEETHY will demonstrate how the operation of the electrolyser can ensure an optimized revenue concerning by-products and grid services.

Keywords: anion exchange membrane,water electrolysis,seawater,industrial symbiosis