Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Decision Toolbox for cities to improve air quality, biodiversity, human wellbeing and reduce climate risks by planting more trees in our cities (100KTREEs)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: EU Space
Destination: EU Space
Action type: Innovation actions
Countries involved: Bulgaria,Denmark,United Kingdom,Belgium,Italy,France
Call: EGNSS and Copernicus applications fostering the European Green deal (HORIZON-EUSPA-2021-SPACE, 2021)
Start date: 2022-12-01
End date: 2025-11-30
Duration (months): 36.0
Total project cost (EUR): 2279371.0
EU funding (EUR): 1890626.0
Participants: 12
Project status: SIGNED

Most of us live in cities, even though cities are not the healthiest places due to poor air quality, noisy surroundings and lack of recreational spaces. Many cities have few green areas and consist of too much ‘concrete jungle’ which makes for a harsh environment for all living things. With the changing climate, the weather is expected to become more extreme. One such effect will be urban heat islands, which will be even more profound, with heatwaves expected to increase 3 to 10-fold by 20801 depending on the climate scenario. A way of tackling all these issues, is to plant more trees within the urban fabric - a well-recognised, and relatively cheap and efficient measure for cities to adapt to future climatic challenges. In view of this, the ambition of 100KTREEs is to make cities a better and healthier place to live by encouraging municipalities to plant more trees and to optimise the impact of tree planting. The team will support cities by mapping the existing trees and by showing a solid business case for planting new trees, as well as attracting third party sponsorship to make it happen. We need to plant trees now to allow our children to enjoy their shade in 20 years’ time. 100KTREEs will develop a mapping and modelling toolbox to optimise the planting of trees and to monitor the health of the trees, based on Copernicus and in-situ data. By assigning monetary value to the key attributes of a tree, e.g. pollution absorption, cooling effect, noise abatement, flood risk reduction and increased biodiversity, a number of business cases will be developed for our two partner cities, Copenhagen and Sofia. Such business cases will also be used to attract third party financing. By means of a crowd science app we will engage with citizens and create awareness of the wonders of trees, also extending to improved life quality and mental health impacts.

Keywords: city trees,tree detection,tree mapping,urban resilience,tree attributes,biodiversity,air quality,cooling effect,collaborative financing schemes,business cases,citizens engagement
Innovative Nucleic Acids Technologies for Analysis, Detection and Treatment (INT2ACT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy,Spain,Poland,United Kingdom,Ireland,Germany,Israel,Switzerland,Sweden,China,United States
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 5202535.89
EU funding (EUR): 4533813.0
Participants: 26
Project status: SIGNED

In recent years, nucleic acids (NAs) have contributed significantly to advancing the diagnosis and treatment of diseases such as cancer, infectious and rare diseases. Breakthrough technologies like genome editing tool CRISPR/Cas9, direct RNA sequencing, multi-omics analysis procedure for NAs analysis, bioinformatics and machine learning for data analysis, and targeted delivery systems based on lipid nanoparticles (LNPs) prove the increasing interest in NAs applicability. However, the full potential of NAs is yet to be unlocked, and the translation of NAs into clinical practice is still facing many methodological and technological limitations such as low detection sensitivity, limited sequencing capacity, lack of analytical methods for NAs therapeutics, and inadequate in vivo delivery. INT2ACT brings together 6 academic research units and 5 industrial partners to address these limitations by establishing new methods for detecting and analysing NAs in patient liquid biopsies, boosting available procedures for direct RNA sequencing, developing new methods for the synthesis and analysis of antisense oligonucleotides (ASO) libraries, identifying new RNA targets, and optimise NA therapeutics delivery systems. The concept of harnessing NAs in the realm of medicine opens doors to an array of possibilities, including the development of therapeutic vaccines for cancer and innovative ASO-based therapies for addressing a multitude of genetic disorders. While advancing NAs’ research and technologies, INT2ACT will also contribute to forming the next generation of highly skilled experts through an interdisciplinary and intersectoral training programme delivered to 15 Doctoral Candidates. The network-wide training programme is designed to ensure that all INT2ACT fellows will have the skills for a successful career in or outside of research in any sector.

Keywords: nucleic acids detection liquid biopsies direct rna sequencing antisense oligonucelotides therapeutic nucleic acids delivery personalised medicine mitochondrial dna biotherapeutic production
A cutting edge integrated approach to sperm biology and associated reproductive biotechnologies to assist the dairy and beef industries meet growing societal, environmental and economic demands (BullNet)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Ireland,France,Switzerland,Canada,Germany,Denmark,United Kingdom,Spain
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2024-03-01
End date: 2028-02-29
Duration (months): 48.0
Total project cost (EUR): 2718979.2
EU funding (EUR): 2718979.2
Participants: 23
Project status: SIGNED

BullNet, consisting of 8 beneficiaries and 13 associated partner organisations, will build a multi-disciplinary and inter-sectorial research programme designed to unravel the complex underlying biology of compromised fertility of individual bulls. Cutting-edge basic, applied and machine-learning approaches will be used to deliver a robust, flexible semen product from young, appropriately reared and managed, first-season elite sires that can be used successfully for artificial insemination (AI) with predictable and consistent fertility, so as to provide the industry with key tools to meet current emissions and animal welfare demands. BullNet will also lead to the advancement of knowledge in how bull management strategies and semen processing affect the functional and molecular characteristics of sperm, thus opening scientific horizons for new applications in the area of assisted reproduction. The overall aim of this programme is to train a new generation of creative, entrepreneurial and innovative doctoral candidates (DCs) in the area of bull fertility. BullNet will expose DCs to different sectors and they will acquire a comprehensive set of transferable skills working in the specific research area relating to their individual research projects, with an emphasis on the need for technology transfer from academic institutions to commercial users. Moreover, given the wide range of academic and industry organisations involved, the DCs will be able to face current and future challenges in order to convert knowledge and ideas into products and services for economic, technological and societal benefit.

Keywords: bull,reproduction,sperm,epigenetics,embryo,machine learning
The Role of Gender in Medical Care. The Case of the Imperial Habsburg Family (16th–17th centuries) (GendMedHab)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 209483.28
EU funding (EUR): 209483.28
Participants: 1
Project status: SIGNED

The present project aims to reach a full comprehension of early modern medical encounter, exploring how gender differentiation played out at all its levels. In particular, the research establishes a comparison, which has not so far made, between male and female patients in terms of relationship with the physician, trust in ancient medical tradition, ability to negotiate cures, and impact on the outcomes of medical visit. The project also casts light on the women’s self-image as patients, investigating to what extent they participated in the diagnostic and therapeutic processes, and providing a detailed picture of their approach to health, illness and the body. In particular, the research focuses on a relevant case study – the imperial Habsburg family in the 16th and 17th centuries –, and relies on a broad variety of archival patient-centred sources, such as the letters of private character the male and female members of the family sent, and their correspondence with the attending doctors. The medical consultation papers physicians compiled for the family members will be also examined. To achieve the objectives mentioned above, both the social context of the Habsburg courts – political and cultural organisms –, and the factors which influenced the medical practice there – connections between the sovereign’s health and politics, the interdenominational conflicts of the period, the high social status of the Habsburg patients, the hierarchized family structure, and the family members’ different degree of autonomy – will be considered. By intertwining social history of medicine, gender history, history of material culture, and history of emotions, the research will unveil how medical practice impacted on the imperial family’s self-determination and identity both as a collective political body and as individuals. The project will be conducted at Istituto Storico Italo-Germanico (ISIG) of Fondazione Bruno Kessler of Trento (Italy), a European leading research institute

Keywords: habsburg family court medicine early modern medical practice female patients patient doctor relationship
High Surface Area Macro-photoinitiators for Broad Range Solar Light Utilization, from Lab-to-Fab (MacroPiN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 242260.56
EU funding (EUR): 242260.56
Participants: 1
Project status: SIGNED

Converting high energy consuming reaction techniques to energy efficient methods is probably the main interest of modern society, not only for economic reasons but also to avoid extended green-house gas release. In this context, light-driven methods such as photocatalysis is very interesting when compared to the conventional catalytic methods which require heating and/or high pressures. Photopolymerization is an environmentally friendly technique to produce polymers since it is a light-driven process, which even can be conducted under natural sunlight. Photoinitiators are one of the essential components of the photopolymerization. Traditionally, these compounds are introduced to reaction mixture alongside with the monomers homogeneously, which makes it very hard to remove and reuse them. That being said, there are examples of macrophotoinitiators (MPIs), which kick-starts the photopolymerization reactions heterogeneously. However, such compounds are not systematically investigated, therefore, comprehensive studies covering syntheses of electronically adjusted MPIs to be facilitated in broad range of photopolymerization reactions from small- to big-scale are needed. In this proposal (MacroPiN), we aim to conduct various photopolymerizations by using tailor-made MPI out of porous organic polymers, which offers high accessible surface areas and advanced photophysical features along their high-dimensional and hydrothermally stable backbones. In following, increasing the hydrophilicity of the produced MPIs to further utilize them in aqueous media (i.e. to investigate them in relatively more environmentally friendly conditions) will be an interest. Finally, aside performing photopolymerizations in batch, continuous flow reactors will be used to scale-up the photopolymerization products in a semi-autonomous and more “user-friendly” way. Therefore, the proposed research aligns very well with the “climate” and “zero pollution” ambitions of European Green Deal.

Keywords: porous polymers,photopolymerization,covalent organic frameworks,porous organic polymers
Displacing Universities – Refugee Voices for Higher Education in Europe (DISPLACING-UNIS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Ireland
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 215534.4
EU funding (EUR): 215534.4
Participants: 1
Project status: SIGNED

Displacing Universities – Refugee Voices for Higher Education in Europe (DISPLACING-UNIS) is a critical ethnographic study into university initiatives for displaced people. The project interrogates differing approaches to refugee higher education (HE) amongst students, alumni, teachers, and admin staff across multiple scales in a historically-sensitive manner, embedding the analysis relationally to changes in HE, civil society/activist practices, and European and local policies. The research will be undertaken with the hope of improving the workings of refugee education initiatives (e.g. in their focus, scope, aims, pedagogies, intersectional awareness), university practices more broadly (e.g. in recognition of prior learning for admissions, trauma informed teaching) and HE’s wider response to displacement and learning (e.g. with education as a means of mobility and social justice for marginalised learners). Aside from scholarly and public-facing outputs (i.e. articles, a book proposal, audio documentaries, podcasts), the project will include specific recommendations for existing initiatives and produce an EU-level policy paper on the role of initiatives for displaced learners' access and success in HE. This will be reworked into locally specific toolkits for HE practitioners and policy makers. Data will be gathered on both a global level, via a collaborative podcasting-as-research method, and through three case studies in Dublin, Budapest and Barcelona, including via participant observation, interviews, curriculum analysis and participatory audio documentary production. I am an anthropologist and refugee education practitioner, and will use the fellowship to build on my experience to develop expertise in both refugee and higher education studies, as well as know-how in cutting edge participatory methods and effective policy intervention.

Keywords: refugee higher education initiatives
Precision nutrition and postprandial immune responses (NUTRIOME)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Norway,Poland,Netherlands,Germany,Denmark,Finland,Sweden,Ireland,United Kingdom
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2023-10-01
End date: 2027-09-30
Duration (months): 48.0
Total project cost (EUR): 2799763.2
EU funding (EUR): 2799763.2
Participants: 16
Project status: SIGNED

A grand challenge for sustainable development in Europe is to improve public health through reducing incidence of non-communicable diseases, premature mortality and health costs. An unhealthy diet is one of the most important risk factors for the global burden of diseases. Therefore, changing the dietary habits in the population is urgently needed. Precision nutrition is an important area for EU's research and innovation policy Food2030 and has emerged as a paradigm with promising results that could help to improve health in the post-genome era. To allow development of more effective preventive strategies via precision nutrition, the determinants driving the inter-personal differences in response to specific foods and meals need to be better understood. This implies also the underlying mechanisms causing differential responses. We eat meals several times per day and are constantly in the postprandial phase. Postprandial changes in circulating metabolites play a major role on human health and the immune response. This leads to the question if one can predict the type of meal, which will be most beneficial to improve an individuals’ metabolic health. Once such knowledge emerges, tailored stratified dietary advice can be developed and evaluated. The focus of NUTRIOME is to train 10 Research Doctoral Candidates (RDCs) in data-driven precision nutrition using two complementary training strategies to learn how to handle and combine multi-omics data, to evaluate the response to foods and diets. We will provide multi-disciplinary training, so that the RDCs: i) are able to utilize, share and disseminate public available multi-omics data, ii) know the regulations and routine for collaborative data sharing in a FAIR manner, and iii) are experts in analyzing, integrating and interpreting increasingly complex data. This will provide a new competence profile to resolve a bottleneck for development of personalised preventive solutions for improved health in Europe.

Keywords: precision nutrition,cardiometabolic diseases and prevention
European Union Contest for Young Scientists 2025 (EUCYS2025)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Other ERA
Destination: Other ERA
Action type: Coordination and support actions
Countries involved: Latvia
Call: European Union Contest for Young Scientists (EUCYS) 2025 (HORIZON-WIDERA-2025-EUCYS-IBA, 2025)
Start date: 2025-04-01
End date: 2026-01-31
Duration (months): 10.0
Total project cost (EUR): 999875.0
EU funding (EUR): 999875.0
Participants: 1
Project status: SIGNED

The proposal outlines the organisation of the 36th annual summit, European Union Contest for Young Scientists 2025, EUCYS, which is to be held in Riga, Latvia, in September of 2025. The European Union Contest for Young Scientists (EUCYS) has been hosted in various European nations since 1989 and its main goal has always been to advance science and research across regions. The event highlights the work and the ideas of young researchers, giving them a platform to showcase their passion and interest. It also provides an opportunity for young scientists to connect with their peers and seek perspective from accomplished mentors. EUCYS encourages young scientific talents to share their skills and interests and to receive mentorship from leading scientists in Europe. Through this initiative, EUCYS aims to bolster national and regional efforts to inspire young people to pursue careers in science and technology. National Centre for Education Republic of Latvia (NCE) is the official host of EUCYS 2025. NCE plans to host young scientists from all over Europe to provide inclusive and encouraging experiences for young and upcoming European scientists. NCE has broad experience organising international educational events that circle around empowerment and education for young people, for example “Future Heroes” girls leadership program and various Erasmus + functions (Green Micro Credentials pathways: Upskill and Reskilling Low Skilled Adults for Lifelong Learning, InClass - Using Telepresence Robots in the Classroom, Good DEEDs - Digital Energy Efficiency Designers, etc.). NCE is a public administration institution directly subordinated to the Minister of Education and Science which is very honored by the opportunity to host EUCYS 2025 in Latvia and welcome science enthusiasts from 40 different countries.

Keywords: european union contest for young scientists 2025 eucys,riga latvia,youth,science,steam,youth development
A two-photon compound fiberscope to study the brain at all spatial and temporal scales. (2P-BRAINSCOPY)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1708614.01
EU funding (EUR): 1708614.0
Participants: 2
Project status: SIGNED

Understanding how neuronal circuits process information is a major scientific challenge, which demands new tools to address the complexity of the brain in animals during natural functioning. Two-photon (2P) microscopy, combined with optogenetics, has revolutionized neuroscience thanks to the possibility to image and photostimulate neuronal activity with light, but suffers from important limitations. To determine how perception and behaviour arise, we need to record and manipulate at will the activity of every neuron in a circuit in freely behaving animals. 2P microscopy is on the contrary mainly performed in head-fixed animals, which poses a clear limitation to the study of natural behaviour. At the same time, understanding how different brain areas exchange information requires to maintain single cell spatial resolution (~ 15 μm) and temporal resolutions compatible with the propagation of neuronal signals (~ 1 ms) over ultra large spatial scales (5 mm), which is today completely out of reach for 2P microscopy. In this project I will overcome these limitations and develop the 2P compound fiberscope, a new optical technique based on the unique combination of multiple optical fibers and optimal spatial and temporal beam shaping approaches, which will completely change the way we study neuronal circuits thanks to two main technologies. 1) A flexible 2P micro-endoscope to image and photostimulate neurons in freely moving animals, which will give access to entire brain regions with the highest imaging and manipulation efficiency and the fastest acquisition speed. 2) The first 2P mesoscope specifically conceived to image and manipulate neuronal activity with single cell resolution across the majority of the mouse cortex on temporal scales compatible with the propagation of neuronal signals. These technologies will pave the way for a real understanding of how neuronal circuits drive behaviour, and how different brain regions communicate to process neuronal information

Keywords: two photon microscopy,optical fibers,micro endoscopy,optogenetic photostimulation,computer generated holography,calcium and voltage imaging,large field of view microscopy,kilohertz imaging,brain circuits,all optical study of the brain,wavefront shaping