Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Inpainting-based Compression of Visual Data (INCOVID)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Germany
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-10-01
End date: 2022-09-30
Duration (months): 60.0
Total project cost (EUR): 2460000.0
EU funding (EUR): 2460000.0
Participants: 1
Project status: CLOSED

Generating huge amounts of visual data, be it images or videos, has never been easier than today. This creates a growing demand for lossy codecs (coders and decoders) that produce visually convincing results also for very high compression rates. Popular transform-based codecs such as JPEG and JPEG 2000 have reached a state where one cannot expect significant improvements anymore. To go beyond their limitations, fundamentally different ideas are needed. Inpainting-based codecs can change this situation. They store only a small, carefully optimised part of the data. In the decoding step, the missing information is filled in with a suitable inpainting mechanism. A successful realisation of inpainting-based codecs can offer decisive advantages over transform-based codecs: The stored information is more intuitive and closer to the mechanisms of human perception. Moreover, the concept is very flexible: It allows to integrate a number of different features and can be tailored towards dedicated applications. Most importantly, the higher the compression rate, the larger are the qualitative advantages over transform-based codecs. However, the potential of these codecs is widely unexplored so far, since difficult fundamental problems must be solved first. This includes optimisation of the data and the inpainting process, sophisticated data coding, and the design of real-time capable sequential and parallel numerical algorithms. We are committed to addressing all these challenges in an integrated approach: We cover the entire spectrum from its theoretical foundations over benchmarking and highly efficient numerical algorithms to codecs for specific applications, and a real-time 4K video player as demonstrator. This will lift inpainting methods from a visually pleasant image editing tool to a fundamental paradigm in coding. Research results that enter forthcoming coding standards will also have an impact on everybody's daily life.

Keywords: inpainting,image compression,partial differential equations pdes,variational methods,exemplar based inpainting,video coding,optical flow,numerical algorithms,optimisation
Artificial Cells with Distributed Cores to Decipher Protein Function (ACDC)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Emerging themes and communities
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Switzerland,France,United Kingdom
Call: FET Proactive: emerging paradigms and communities (H2020-FETPROACT-2018-01, 2018)
Start date: 2019-01-01
End date: 2023-07-31
Duration (months): 55.0
Total project cost (EUR): 4376295.0
EU funding (EUR): 4376295.0
Participants: 6
Project status: SIGNED

We envision a future where ‘chemical apps’ on mobile devices produce on demand valuable compounds for health and performance as well as apps for bioagent threat detection and disease. To take concrete and defined steps toward this future vision, we will exploit the miniaturization provided by lab on a chip technology and construct responsive architectures and metabolism based on living cells and tissues. We will build programmable and re-configurable, (bio)chemical processes, with precision, order, and as hierarchical cellular constructs, in the same way as living systems. We will enable microscale, liquid-based, chemical compartmentalisation (cores), and inter-compartmental (core-core) communication, just as one finds in organelles, cells and tissues. ACDC will focus on developing this next generation technology through a detailed workplan that heavily involves the nontrivial tasks of integrating diverse state of the art technologies including microfluidics, microwave resonators, DNA-based supramolecular assembly, in vitro gene expression and the integration of membrane channels into a functional platform. In a future embodiment of this project, artificial cell technology will be used as programmable and reconfigurable matter for specific applications, including theranostics and personalized medicine as well as sensing and actuation in the environments for bioremediation. As the first steps towards that future vision, we aim to produce an artificial technological construct and process that recapitulates some aspects of living systems on the microscale, and therefore this project will produce exemplars of secondary living technologies concentrating on the wetware class [1] but also a multi-level mathematical framework. We have assembled an international, interdisciplinary team from academia, industry and public engagement. Our outreach and engagement programme will define the impact in both the public and economic sectors with ethical dimensions considered. Further, building upon 55 years of collective start-up enterprise experience, we will explore the translation of new intellectual property generated into commercial advantage and job creation for the European Union.

Keywords: microfluidics,dna barcoding,chemical compiler,diy bio,protocells,artificial life,lipid bilayers,chemicals compartmentalisation,transmembrane proteins
Security of Air Transport Infrastructure of Europe (SATIE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Protect and improve the resilience of critical infrastructures, supply chains and tranport modes
Action type: Innovation actions
Countries involved: Austria,Germany,Italy,Italy,Germany,Spain,Germany,Slovakia,Greece,Croatia,Greece,Greece,Poland,France,France,France,Portugal,Portugal
Call: Prevention, detection, response and mitigation of combined physical and cyber threats to critical infrastructure in Europe (H2020-SU-INFRA-2018, 2018)
Start date: 2019-05-01
End date: 2021-10-31
Duration (months): 30.0
Total project cost (EUR): 9890595.0
EU funding (EUR): 7989264.0
Participants: 20
Project status: CLOSED

The twenty-first century experiments a digital revolution that simplifies flight and cross-border. Digitalization contributes to leverage information sharing, reduce exploitation costs and improve travel experience, but it also blurs the lines between virtual world and reality with serious security matters. In the meanwhile airports face a daily challenge to ensure business continuity and passengers’ safety. SATIE adopts a holistic approach about threat prevention, detection, response and mitigation in the airports, while guaranteeing the protection of critical systems, sensitive data and passengers. Critical assets are usually protected against individual physical or cyber threats, but not against complex scenarios combining both categories of threats. In order to handle it, SATIE develops an interoperable toolkit which improves cyber-physical correlations, forensics investigations and dynamic impact assessment at airports. Having a shared situational awareness, security practitioners and airport managers collaborate more efficiently to the crisis resolution. Emergency procedures can be triggered simultaneously through an alerting system in order to reschedule airside/landside operations, notify first responders, cybersecurity and maintenance teams towards a fast recovery. Innovative solutions will be integrated on a simulation platform in order to improve their interoperability and to validate their efficiency. Three demonstrations will be conducted at different corners of Europe (Croatia, Italy and Greece) in order to evaluate the solutions in operational conditions (TRL≥7). Results and best practises will be widely disseminated to the scientific community, standardization bodies, security stakeholders and the aeronautic community. Finally, SATIE paves the way to a new generation of Security Operation Centre that will be included in a comprehensive airport security policy.
A transcriptomic approach to understand the avian genetic susceptibility to West Nile Virus infection (TransWNV)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-10-15
End date: 2021-02-15
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Emerging infectious diseases that have a wildlife reservoir pose a major challenge to global health. This is the case for West Nile Virus (WNV), which is the number one causative agent of viral encephalitis worldwide. Although it infects humans, the main hosts of WNV are birds. Thus, to develop effective intervention strategies it is critical to understand the disease dynamics in birds. In WNV, disease dynamics are influenced by variation in disease susceptibility across individuals and species, but the factors underlying this variation are poorly understood. Here, I propose to focus on one of these factors: the genetic basis of the immune response. Specifically, I will characterize the transcriptional response to WNV infection and identify candidate genes and pathways that will allow us to gain insights into the avian immune response to the virus and uncover the genetic basis of susceptibility both at the species and individual level. To achieve this goal, I will first analyze the transcriptional response in individuals of house sparrow that die and individuals that survive a WNV infection and test for differential expression. Second, I will characterize the transcriptional profile of house sparrows inoculated with 4 different strains of WNV. Finally, I will examine transcriptional profiles and test for differential expression in 3 species (house sparrow, Eurasian collared dove and common quail) with different susceptibility to WNV. To complete this work I will use state-of –the-art genomics, bioinformatics and statistical analyses and will integrate knowledge from genomics, disease ecology and immunology. Obtaining a Marie Sklodowska-Curie fellowship to carry out this project under the supervision of Prof. J Figuerola (Doñana Biological Station) will be a unique opportunity to resume my scientific career. This project will also contribute to one of the key research areas in the European Union and will yield new insight into the mechanisms relevant to host health.

Keywords: transcriptional response,immune response,host pathogen interactions,wildlife disease,emerging infectious diseases
Vulnerability Search and Prevention through Holistic End-to-end Risk Evaluation (V-SPHERE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Norway
Call: Engaging SMEs in security research and development (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-02-01
End date: 2018-05-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In the so-called ‘age of information’, information and communication systems (ICT) are the backbone of our digitalised society. Especially from an industrial perspective, we entrust our most delicate details to these tools and, logically, we demand the highest level of integrity and availability to avoid any eventual data loss, unavailability or, maybe more important, misuse. However, cyberattacks in EU are costing businesses around €38 billion/ year. How can we maximise our protection against these risks? Our company, Prosa Security, is developing V-SPHERE; a new solution for industrial cyber security that unveils and prevents vulnerabilities of any ICT system in a holistic way, i.e., covering all the development cycle and all company perspectives. Involving all the stakeholders in the security process, this unique approach has demonstrated to be 10 to 100 times more effective in detection than traditional methods, as well as to reduce by 3 the time allocated for quality and security assurance in SW development projects, resulting in saving from €45,000 to €300,000 per SW development project. The overall objectives of this project are: assessing the viability of V-SPHERE and building a solid business and operational plan (Phase 1); conducting the planned technical and commercial activities to prepare its commercialisation (Phase 2); and initiate the formal large scale commercialisation, seeking the promotion of V-SPHERE and the networking with financers (Phase 3). Our business opportunity is promising, with the European market of cybersecurity to reach €38.10 billion and the specific market of security testing solutions valued at €2.71 billion in 2022. The expected outcome of the project is estimated at €23.3 million by 2023, besides the creation of 27 job positions.

Keywords: vulnerability,cybersecurity,sw quality assurance,sw develolpment
EU NETWORK OF REGIONS ON SUSTAINABLE WOOD MOBILISATION READY FOR DIGITALISATION (ROSEWOOD4.0)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Coordination and support actions
Countries involved: Italy,Germany,Ukraine,Germany,Spain,Austria,Belgium,Romania,Sweden,Switzerland,Finland,Finland,Finland,Croatia,Poland,Slovakia,Slovenia,Greece,Norway,France,Portugal
Call: Thematic networks compiling knowledge ready for practice (H2020-RUR-2019-1, 2019)
Start date: 2020-01-01
End date: 2022-06-30
Duration (months): 30.0
Total project cost (EUR): 2047901.25
EU funding (EUR): 2047901.25
Participants: 23
Project status: CLOSED

ROSEWOOD4.0 builds on the well-established ROSEWOOD network of Regional Hubs connecting multiple actors along the forest value chain to reinforce the sustainability of wood mobilisation in Europe. The new action will especially reinforce and enlarge the links with Eastern Europe by creating a new Eastern Hub including new countries (Poland, Slovakia, Ukraine). Secondly, the action puts special emphasis on digitalisation (forestry industry 4.0) and digital tools (social media, platforms, e-learning) for training and coaching, enabling practitioners to share know-how with much wider impact. The focus on ICT addresses the two main challenges in wood mobilisation: 1) better access to resources through defragmentation of forest owners and 2) increased volume to the market and higher transparency. The project’s extensive dissemination of best practices, technological and non-technological innovations and research results feeds directly into national and regional Agriculture Knowledge and Innovation Systems (AKIS) in forestry and builds an efficient interface with the EIP-AGRI and the EIP Raw Materials, supported by the European networks EFI and InnovaWood. The multi-actor action closes knowledge gaps, connects and transfers tangible knowledge and best practice between forestry practitioners across the whole Europe. In an open innovation environment, the coordination of Regional Hubs facilitates also new opportunities for exploitation of near to market innovations and fosters business partnerships between stakeholders, aligned with local and regional development plans, to complement existing or initiate new Operational Groups within the EIP-AGRI. ROSEWOOD4.0 will contribute to enhanced competitiveness of the forest industry and to vital development in rural areas within the European Bioeconomy by responding to the imminent need for broader sharing of ICT-driven solutions in forestry.

Keywords: wood mobilisation
Field Programmable Photonic Arrays (FPPAs)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Spain
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2019-10-01
End date: 2021-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The core concept behind this POC proposal spins-off from the activity of the Advanced Grant ERC-ADG-2016-741415 UMWPCHIP. It will establish the innovation potential behind a novel and revolutionary concept, the Field Programmable Photonic Array (FPPA). The FPPA has a similar rationale as the FPGA in electronics: A common hardware is designed to provide several resources that can be employed to implement different functionalities by means of programming. However, the FPPA is different from the FPGA in the sense that it does not carry digital logic operations but rather exploits optical interference to perform very high-speed analog operations acting over the phase and amplitudes of optical signals in a controlled environment provided by the chip's reduced footprint. The overall aim is to develop the first steps of this process that include: the technical and commercial viability; development of IPR strategy; establishing connections for later stage funding and covering the initial expenses for establishing a spin-off company. To achieve the project overall goals, I have organized the work-plan into three main tasks. T1: Hardware Development, T2: Software Development and T3: Technology transfer and Spin-off constitution.This combined effort to be undertaken through ERC PoC will provide both a strong technical as well as business foundation for my revolutionary FPPA concept. To my knowledge neither any other research group nor any other company in the world has proposed so far a similar integral approach towards a generic programmable photonic product such as that of the FPPA. Clearly, there is an extraordinary window of opportunity for developing this innovative concept, opening the path towards overcoming the death of More's Law enabing future flexible integrated chips incorporating both electronics and photonic parts. This PoC project will be the first leading to the creation of a European spin-off company in the field of programmable photonics.

Keywords: programmable integrated photonics,integrated optics,silicon photonics
EMpowering PAtients for a BeTTer Information and improvement of the Communication Systems (EMPATTICS)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: COFUND actions
Countries involved: Spain,Spain,Spain,Spain,Ireland,Slovenia,France,United Kingdom,Denmark
Call: Self-management of health and disease and patient empowerment supported by ICT (H2020-PHC-2015-single-stage, 2015)
Start date: 2016-02-01
End date: 2020-11-30
Duration (months): 58.0
Total project cost (EUR): 4000000.0
EU funding (EUR): 2800000.0200000005
Participants: 11
Project status: CLOSED

This project will research and define how health and care professionals and patients will use ICT technologies to plan interventions with patients and to monitor the progression of their physical and mental state. It will investigate and document the requirements for Decision Support Tools that can be created, deployed and embedded into the daily routines of patients and Health and Care Professionals to deliver quality standardised care across a large population of chronic and elderly patients. This will include the technology requirements and use cases for sharing Care Plans between professionals and patients as well as the scope and depth of integration between new productivity and care coordination toolsets and current EMR recording software. EMPATITCS will undertake further research and collate current global examples of self-management services that have been clinically proven to positively impact the health of a population. It will study the socio-economic and age dependency factors that affect awareness, uptake and adherence to self-management services. This will define and design a best in class self-management service that provide the educational and informational services that a large population of elderly and chronic patients require to self-manage. The emphasis will be of the use of appropriate technology to scale the service and to connect with population groups that are difficult to reach due to geographic or demographic factors.

Keywords: empowerment,adherence,chronic diseases
The Mechanisms and Dynamics Controlling Cycles of Lymph Node Expansion (LNEXPANDS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-03-01
End date: 2023-08-31
Duration (months): 66.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Lymph node swelling is a classical hallmark of immunity. This expansion is observed by doctors, researchers and patients, yet as obvious as this process is, our understanding of the remodelling mechanisms involved are in their infancy. Lymph node remodelling is rapid and yet completely reversible, occurring countless times throughout our lifetimes. The purpose of this proposal is to understand how lymph node remodelling occurs and is resolved, repeatedly; to understand immunity in a whole organ context. The architecture of lymphoid organs is key to the effective operation of our immune system and is dictated by structures formed by non-haematopoetic stromal cells, including endothelial cells, and fibroblasts. Beyond their structural roles, stromal cells play an active role in immune responses, and the field of stromal immunology has become one of the most dynamic and exciting areas of immunology research. In this proposal I focus on the changing behaviour of fibroblastic reticular cells (FRCs) throughout cycles of lymph node remodelling. Fibroblastic reticular cells (FRCs) are the most abundant lymphoid stromal cell population, and form an interconnected network spanning the full volume of the tissue. FRCs are highly contractile and are able to relax and stretch during early phases of lymph node remodelling. FRCs proliferate during later phases of lymph node growth but are then removed as homeostasis is restored. Throughout this proposal I will use an extensive range of systems, ranging from proteomics and biochemistry to intravital imaging. I aim to: 1) To discover how spreading and stretching of the existing fibroblastic reticular network is directed in the acute phase of expansion: 2) To discover the cellular cues inducing the switch from stretching to proliferation and growth of the fibroblastic reticular network and 3) understand how homeostasis is regained as immune responses are resolved.

Keywords: lymphoid tissue,fibroblastic reticular cell,dendritic cell