Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Coordination of European Research on Industrial Safety towards Smart and Sustainable Growth (SAF€RA)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Integration
Action type: Coordination and support actions
Partnership: SAF€RA (ERA-NET)
Countries involved: Finland,France,France,Germany,Greece,Italy,Netherlands,Netherlands,Netherlands,Poland,Serbia,Spain,Norway,Czechia,France,Spain
Call:  (FP7-ERANET-2011-RTD, 2011)
Start date: 2012-04-01
End date: 2015-03-31
Duration (months): 36.0
Total project cost (EUR): 2164136.0
EU funding (EUR): 1494988.0
Participants: 20
Project status: CLOSED

Industrial safety is an enabling and important success-factor in the pursuit of beneficial business activities. For this reason, industrial safety is a vital and important prerequisite for sustainable growth and competitiveness of the EU. Therefore, there is an urgent need to refocus the resources of national research programmes in EU Member States on industrial safety since the problems related to industrial safety are common to all and cannot be tackled adequately at the national level. SAF€RA will bring dynamism into European research on industrial safety by fostering collaboration of national research programmes, by encouraging lateral thinking and by promoting innovations related to implementation of industrial safety. The Consortium consists of 19 leading public agencies, ministries and research organizations funding or managing safety research working in close collaboration with stakeholders from industry, enterprises, authorities, science, social partners and society at large. The strategic objective of the SAF€RA project is to create a research and innovation market through systematic exchange of information and a stepwise integration of national research programmes in the EU by creating effective instruments which will emphasize collaboration between national research programmes on industrial safety. The goal is thus to promote the incorporation of a more effective safety culture into EU industrial activities to improve the competitive edge of European industries on a global scale. The scope of the SAF€RA will be to support traditional industries to solve existing safety challenges and to promote innovative novel industries, such as bio- and nanotechnology-based industries, to consider safety issues in all their activities from the outset. The SAF€RA therefore aims at improving the safety of European industries to promote sustainable growth as well as sharpening their competitive edge.

Keywords: industrial safety,sustainable growth,competitiveness,joint activity,major accidents,nanosafety,european research area,joint programme,new and emerging risks
New International Fellowship Mobility Programme for Experienced Researchers (NEWFELPRO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Croatia
Call:  (FP7-PEOPLE-2011-COFUND, 2011)
Start date: 2013-01-01
End date: 2017-12-31
Duration (months): 60.0
Total project cost (EUR): 6982241.08
EU funding (EUR): 2792896.43
Participants: 1
Project status: CLOSED

NEWFELPRO is a fellowship programme of the Government of Republic of Croatia through the Ministry for Science, Education and Sport (MSES). The long-term objective of the “New International Fellowship Mobility Programme for Experienced Researchers” is to contribute to the presence of significantly more research qualified individuals who can become future leaders of universities and colleges, research groupings, research institutes and innovative companies, presenting a significant international trans-national experience and well developed international scientific networks. The programme will be focused on a combination of actions connected with transnational and inter-sector mobility. The strategic objectives of the programme are: - Give new impulse at the national research programmes for foreign researchers, encouraging incoming mobility of experienced human resources (New incoming fellowship scheme). - Facilitate additional mobility in the Croatian research community, increasing the participations of Croatia's scientists abroad (New outgoing fellowship scheme); - Reverse the “brain drain” process, encouraging brilliant Croatian researcher to build up his own carrier in Croatia also inviting them to return in their country (New reintegration fellowship scheme); - Internationalize the research developed of all Croatian universities fostering confrontation with the best international research competitive institutions (all schemes); - Give impulse to an effective labour market for researcher in Croatia, connecting industry and universities, public and private research institutions and industrial laboratories, enhancing the knowledge transfer and preparing better employment opportunities for researchers with special attention at SMEs innovative processes (all schemes).

Keywords: health sciences,humanities,natural sciences,physical sciences,social sciences
JPI’s: a process of mutual learning: TOwards a COmmon adoption of frameWORK (JPIS TO CO-WORK)

Framework: FP7 — Cooperation
Programme: General Activities
Destination: ERANET
Action type: Coordination and support actions
Partnership: JPIS TO CO-WORK (ERA-NET)
Countries involved: Spain,Austria,Sweden,Germany,Austria,Poland,Germany
Call:  (FP7-ERANET-2011-RTD, 2011)
Start date: 2011-10-01
End date: 2014-03-31
Duration (months): 30.0
Total project cost (EUR): 801912.86
EU funding (EUR): 597295.0
Participants: 7
Project status: CLOSED

The European Research Area (ERA) New Perspectives Green paper published in 2007, stressed the importance of overcoming the fragmentation of research activities, programmes and policies across Europe. To respond to this need this document proposed a joint programming, implementation and evaluation of public research investments at European level on issues that go beyond the capacities of individual countries. As a consequence, the European Council of March 2008 called the Commission and Member States to explore the potential of Joint Programming in research, and to launch first activities in this field by 2010. In July 2008, the European Commission launched its proposal with the Communication ‘Towards Joint programming in research: Working together to tackle common challenges more effectively’. This proposal was welcomed by the Council by December 2008, and agreed to launch the process, but focused on that challenges which no Member State is capable of solving alone. Upon this invitation from the Council, it has been agreed to develop 10 Joint Programming Initiatives (JPI) in total that are at a different stage of development. As the JPI’s involve different institutions from different countries, with different procedures, since the beging of the JPI process it was stated the need of providing guidelines on Framework Conditions (FC) to facilitate a harmonised planning and implementation of joint research programmes. The main objective of this support action is to organize a process of mutual learning between all the running JPIs, mainly focused on common challenges that framework conditions and the best contribution of JPIs to the ERA within the strategy Europe 2020. The objective of this project is thus to provide a forum to continue the discussion, exchange of experiences and best practices, and the implementation of a process of mutual learning amongst ongoing and future JPIs.

Keywords: jpint programming,eranet,foresight activities,programme evaluation,project evaluation,ipr
Network of European funding for Neuroscience research (ERA-NET NEURON II)

Framework: FP7 — Cooperation
Programme: Health
Destination: Translating research for human health
Action type: Coordination and support actions
Partnership: ERA-NET NEURON II (ERA-NET)
Countries involved: Germany,Luxembourg,Poland,Israel,Austria,France,Finland,Sweden,Romania,Italy,Spain,United Kingdom,Canada,Iceland,Portugal,Belgium
Call:  (FP7-ERANET-2011-RTD, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 2206402.75
EU funding (EUR): 2000000.0
Participants: 23
Project status: CLOSED

Research into the human brain and its diseases is one of the key challenges of our century, since among the many diseases affecting health, disorders of the brain are major causes for impaired quality of life. Despite some progress in understanding the molecular mechanisms of the various neurological and psychiatric disorders, research is far from being able to offer solutions how to conquer them and the development of curative treatments or prevention strategies has not been very successful. Thus, a concerted effort of research groups and the organisations funding them is needed to reach the long term goal of curing patients with disorders of the brain and nervous system and helping their relatives. Due to the importance of research into the area of brain diseases, a variety of independent national and regional funding programmes exist in most countries. This contributes to fragmentation of available financial resources, to a lack of synergistic approaches and to duplication of efforts in the funding bodies. The proposed ERA-NET NEURON II aims to coordinate national and regional programmes for disease-related neuroscience research in 21 participant funding organisations across 16 European Member States, Candidate and Associated countries, and Canada. Extending the collaboration beyond the European Research Area into North America reflects the global dimension of brain research and adds even more to the effectiveness of NEURON. The ERA-NET will serve as a platform of programme opening for participating funding agencies and ministries and coordinate high quality research by funding research groups originating from the NEURON II partner countries. NEURON II will build on the achievements of its predecessor ERA-NET NEURON. It will launch a series of transnational joint calls for proposals and address new ambitious goals by developing strategies towards a self-sustainable network with a long term perspective.

Keywords: disease related neuroscience research
Inkjet-Printed organic Photodetectors for Imaging Applications (IPPIA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2011-09-01
End date: 2014-08-31
Duration (months): 36.0
Total project cost (EUR): 75000.0
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

The recent development of a wide range of solution processable functional materials, especially organic semiconductors and highly conducting metal inks, and the broad availability of graphical arts printing technologies are at the base of a revolution which will lead to the fabrication of organic opto-electronics devices by means of high-throughput, inexpensive mass production processes. Additive printing techniques offer in fact advantages in terms of process simplification, layer-to-layer alignment, compatibility with large areas, and potential cost reduction compared to subtractive lithographic patterning. In particular inkjet, which is a non-contact technique, offers high flexibility and is compatible with a large range of functional materials. It is particularly advantageous when controlled volumes of inks have to be placed in precise positions on a substrate, as for example in the case of organic photodetectors (OPDs). The possibility to tune OPDs responsivity, therefore enabling a selective photodetection, and to deposit them in principle on substrates of any kind and shape, make them very appealing for various advanced applications. Project IPPIA aims to demonstrate inkjet printed OPDs sensitive to the visible spectrum of light, suitable for imaging applications. Dr. M. Caironi will be responsible of this scientific activity, which will take place at the Italian Institute of Technology (IIT), a leading research center in Italy. The final objective of this project is to fabricate small arrays of an organic active pixel by integrating OPDs with suitable organic field-effect transistors, acting as an electrical switch, thus paving the way for cost-effective, light-weight, conformable digital imagers. The expertise of Dr. Caironi in the field, and the infrastructures and complementary expertise available in IIT have a great potential for a successful project and for increasing the overall scientific and technological competitiveness of the European community.

Keywords: technological sciences,organic electronics,plastic electronics,inkjet printing,organic photodetectors,organic field-effect transistors
The Function of the RBP4 Receptor Stra6 during Retinol Saturase Regulated Adipocyte Differentiation (STRA6)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2011-09-01
End date: 2016-08-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Obesity-related metabolic disorders such as type 2 diabetes reach epidemic proportions in most industrialized countries. Retinol binding protein 4 (RBP4), the only specific serum protein for the delivery of retinol to tissues, is increased in obesity and contributes to the development of insulin resistance and type 2 diabetes. The protein encoding stimulated by retinoic acid gene 6 (stra6) was recently identified as the membrane receptor for RBP4, mediating cellular retinol uptake. We discovered that another putative component of retinol metabolism, the oxidoreductase Retinol Saturase (RetSat), promotes adipocyte differentiation, presumably through the generation of a pro-adipogenic enzymatic product. Whether RBP4 and stra6 play a role in the metabolic actions of RetSat is unknown. This proposal is aimed at identifying stra6 as a potential link between RBP4 and RetSat's function in adipocyte differentiation. We will determine if adipocyte stra6 is transcriptionally regulated by the Peroxisome Proliferator-Activated Receptor gamma, the target of anti-diabetic thiazolidinedione drugs, and by weight gain in mice, as is known for RBP4 and RetSat. Furthermore, stra6 gain-and loss-of-function studies will be applied to precursor cells to understand its functions during adipocyte differentiation. Analyzing the retinoid composition after these manipulations will identify retinol derivatives regulating the adipogenic potential. Next, we will investigate whether stra6 is required for the pro-adipogenic effects of RetSat by overexpressing RetSat in stra6 depleted precursor cells and if this is dependent on the presence of RBP4. The findings from this proposal will allow me to supplement my ongoing research on RetSat by exploring its dependence on stra6 mediated retinol uptake. Moreover, they may identify which components of the RBP4/stra6/RetSat axis could present potential therapeutic targets to treat obesity and related metabolic disorders.

Keywords: obesity,rbp4,retinol saturase,stra6,adipogenesis,retinol
Global analysis of R-loop structures (RNA-DNA hybrids) by advanced microscopic and genetic approaches (GLORI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Hungary
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2012-12-01
End date: 2016-11-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Genetic alterations from point mutations to chromosome rearrangements are usually associated with pathological disorders. Unraveling the origin of such events was greatly enhanced by the discovery of cis-acting factors (e.g. chromosomal fragile sites, G quadruplexes) behaving as chromosomal hotspots for genomic instability, but a detailed mechanistic understanding of their mode of action has remained elusive. Most current models of genomic instability incorporate R-loops - nucleic acid structures in which an RNA strand displaces one strand of a duplex DNA molecule for a limited length - as immediate cause of gene rearrangements. The present application is based on prior observations of the host laboratory on previously unrecognized ribonucleoprotein particles containing RNA-DNA hybrids, being positioned at loop-size intervals in the chromatin of lower and higher eukaryotic cells (Szekvolgyi L et al., PNAS, 2007). The molecular identity and the cell biological significance of the revealed structures are unknown. The goal of this project is to unravel the molecular structure and epigenetic landscape of the regularly spaced ribonucleoprotein complexes containing RNA-DNA hybrids previously described by our laboratory, with a special emphasis on their connection to chromatin loop domain formation and genetic recombination. We expect that our work plan - proposing the global analysis of R-loop structures using a range of cell biophysical and genetic approaches in the genetically tractable model organism S cerevisiae as well as in various human cell lines - will yield novel data relevant to the rules that govern not only normal chromatin architecture but also an RNA-DNA hybrid-mediated pathological scenario leading to chromosomal rearrangements.

Keywords: rna-dna hybrid,genetic recombination,gene rearrangements,chromatin loop domain,saccahomyces cerevisiae
Mechanistic and Pharmacological studies of transition-metal ABC transporters that are essential to bacterial virulence. (METAL TRANSPORTERS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2011-09-01
End date: 2015-08-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

In the past 20 years, we have witnessed a constant rise in bacterial resistance to antibiotics. Paradoxically, this has been accompanied by an almost complete exodus of pharmaceutical companies from the antibiotics market. As a result we are facing a situation where our antibacterial toolkit is much depleted and outdated. The goal of the proposed research is to address this deficiency by studying a group of potentially promising novel antibiotic targets: ATP Binding Cassette (ABC) transporters of transition metals. In many clinically important bacterial pathogens (e.g. Streptococcus pneumonia, Mycobacterium tuberculosis, Salmonella typhi) ABC transporters of transition metals have been shown to be essential for virulence/pathogenesis. Remarkably, beyond these observations, little else is known of these systems. We propose to study, and develop inhibitors towards 3 uncharacterized transition metal ABC transport systems that are essential to pathogenesis: ZnuABC of Salmonella typhi, sloABC of Streptococcus pneumonia, and the newly identified Bacillus anthracis (Anthrax) virulence determinant MntABC. Our proposal is comprised of two parts: the first is an in-depth functional analysis of these transporters, aimed at understanding their molecular mechanism. Our second goal, which is inseparable from the first, is to develop inhibitors for these transport systems, laying the foundations for future antibiotic development.

Keywords: membrane proteins,permeation,abc transporters,transition metals,drug development,bacterial multidrug resistance,bacterial virulence
Intelligent Sensor Network and System Technologies for Fish Farming (SENSORFISH)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Germany,Netherlands,Norway
Call:  (FP7-PEOPLE-2011-IRSES, 2011)
Start date: 2012-02-01
End date: 2015-01-31
Duration (months): 36.0
Total project cost (EUR): 405300.0
EU funding (EUR): 380100.0
Participants: 4
Project status: CLOSED

Fish farming is likely to be the greatest source of increased fish production, and its share in total food fish supply by 2030 is estimated almost equal to the food fish supply from capture fisheries. Intelligent monitoring and control system for fish farming generates labor and energy savings, limit disease and mortality, and increase yields by continuously monitoring and controlling water quality. The main objective of SENSORFISH joint research programme is to increase mobility and exchange of researchers between EU countries and China，US to obtain better understanding of intelligent sensor network and system technologies for fish farming. This program will focuses on four areas: 1) Smart Sensors for fish farming; 2) Wireless sensor network for fish farming; 3) Remote control and management system for fish farming; 4) Integration of fish farming system. An intelligent monitoring and control system for fish farming will be pilot used and tested in Norway and China. The results of these contributions will be made available to the academic community, and research conclusions drawn will be published in international journals. In these Staff Exchanges each participant will also seek to share their knowledge within their area of expertise by organizing training seminars, courses for early stage researchers also involving local, regional and/or national management agencies according to their needs or demands. SENSORFISH programme builds a basis for long-term collaboration among participants and will exploit complementary expertise of the participant organizations and participants in order to create synergies among participants and to establish long-lasting partnership. As multi- and cross-disciplinary studies essential in intelligent sensor network and system technologies for fish farming research are lacking in China, this programme will essentially also work towards an integrated approach for future joint international projects.

Keywords: engineering,smart sensor,sensor network,system technologies,fish farming,fishery,aquaculture,marine,climate change