Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Quantitative and Experimental Biology (QUANTEXBIO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Doctoral programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Austria,Germany,Israel,Italy,Switzerland,Norway,Greece,Poland,France,Netherlands,United Kingdom,Portugal,United Kingdom
Call: Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) (H2020-MSCA-COFUND-2014, 2014)
Start date: 2015-11-01
End date: 2020-10-31
Duration (months): 60.0
Total project cost (EUR): 3348480.0
EU funding (EUR): 1674240.0
Participants: 22
Project status: TERMINATED

Biology is in an era in where the formerly dominant mode of experimentation is complemented by sophisticated data analysis, theoretical modelling and visualization strategies. Perhaps the most critical challenge is to train scientists, able to craft questions that are amenable to interrogation of big data and vice versa. Centred at the University of Dundee’s College of Life Sciences (CLS), the QUANTEXBIO programme will offer a unique menu of doctoral training projects and mobility to a cohort of high-quality ESRs. This inter-disciplinary programme will provide research training at the highest levels of excellence with supervision by leaders in the fields of Life Sciences, Bio-physics, Mathematics, Computing and Computational Biology. Research projects for each 4 year training programme will be chosen by each ESR, with a transparent evaluation and fellowship awarding process based on excellence. The inter-disciplinary research described in these projects is designed to provide great career opportunities for researchers with expertise in quantitative bioinformatics, physics and mathematics based modelling techniques as well as those with strong backgrounds in human and plant life-sciences. Unbounded by traditional research silos, subjects range from cancer and developmental biology to crop growth all unified under a modelling and quantitative sciences approach. Whilst tackling challenging problems that cut across distinct disciplines, interactions and networking opportunities with leading scientists from across the EU will be assured through a flexible schedule of secondment opportunities to leading industrial and academic organisations. A programme of symposia and workshops involving the cohort of researchers, CLS researchers and partner organisations will maximize impact to stakeholders and society at large. The strategic goals for this programme are synergistic with the CLS €30Mn Centre for Translational and Interdisciplinary Research which opened in 2014.

Keywords: computational biology,plant sciences,biophysics,mathematics,computer science,theoretical modelling
Development of prescriptive AnalYtics baseD on aRtificial intElligence for iAMS (DAYDREAMS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: European rail initiative
Action type: Research and Innovation actions
Partnership: Shift2Rail (Art-187)
Countries involved: Germany,Italy,Italy,Italy,Greece,Belgium,France,United Kingdom
Call: Technology Development for Railway Systems Asset Management (TD3.6) (H2020-S2RJU-OC-2020, 2020)
Start date: 2020-12-01
End date: 2023-05-31
Duration (months): 30.0
Total project cost (EUR): 1709875.0
EU funding (EUR): 1709875.0
Participants: 11
Project status: SIGNED

The overall DAYDREAMS objective is to move forward the integration and use of data and artificial/human trustworthy intelligence together with context-driven HMI for prescriptive Intelligent Asset Management Systems (IAMS) in railway by (i) advancing in maintenance approach towards prescriptive asset management, (ii) improving the decision-making process by developing multi-objective decision optimisation approaches taking into account all implications of IAMS decisions in the railway environment, and (iii) reinforcing the role of the person-in-the-loop by designing and developing advanced context-driven HMIs to allow context- and risk-aware multiple-options decision-making processes. The HMI will allow the person-in-the-loop to: (i) properly access and visualise predictions/metrics and models, (ii) assess why and how the model predicts something, (iii) Steer models by setting parameters, and (iv) evaluate alternatives using parameter steering and extending this process through speculative execution. The DAYDREAMS objective will be assessed by validating the proposed solution using the following two-step approach: (i) A first validation at TRL 4 of the approaches (developed prescriptive asset management) using several internal scenarios and one scenario provided by the CFM IN2SMART2 project; (ii) A further validation of the DAYDREAMS methodologies integrated in a TRL 5 prototype using at least two scenarios: at least one internal scenario and the IN2SMART2 scenario. The validation will cover both the performances of the prototypes and its trust for future adoption in multi-actors environments. The validation will be carried out by defining evaluation and validation metrics and KPIs: (i) linked to asset management problems to be solved by the involved Infrastructure Managers (IMs) and related baselines, (ii) quantified and measurable; (iii) referred to high-level KPIs defined in the S2R IMPACT2 CFM project, and (iv) useful to address multi-objective optimisation.

Keywords: railway asset maintenance,prescriptive analytics,machine learning,artificial intelligence,context driven human machine interfaces,human in the loop
European Literature and the “First East Asian War” of 1592-1598 (EURO-IMJIN) (EURO IMJIN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-12-21
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: CLOSED

This project will locate, transcribe, translate, and analyse European accounts of the East Asian War of 1592-1598 (“The Imjin War”), connecting European and East Asian research on the war and opening new horizons for researchers from both regions. The applicant is a specialist of seventeenth century European literature with four years experience teaching and researching Spanish literature at universities in China and Japan. The applicant will build upon his current skill set by receiving Asian history, language, and translation training with a unique team of specialists at the host institution (Universitat Autònoma de Barcelona). This will provide him with a solid foundation for his future research trajectory on the literature of East-West encounters in Asia. Ultimately, the applicant aims to use this opportunity to obtain a permanent academic appointment back in Europe, bringing his knowledge and networks from Asia.

Keywords: spanish golden age literature,chronicles,missionaries in europe,east asian history,global history
All Aqueous, continuous, Solid-Liquid SYNergisticEXTRACTion of rare earth elements (SYNEXTRACT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2017-07-01
End date: 2018-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

It is a matter of strategic independence for Europe to urgently find processes taking into account environmental and economic issues, when mining and recycling rare earth elements (REE). As of 2015, only 1% of used REE were recycled in the EU and 80% of the mining operations were performed in China, hence representing a major Sword of Damoclès for the rest of the world’s economy. With SYNEXTRACT, we propose to leverage on discoveries made (and patented) within ERC-Adv REE-CYCLE, related to new extracting liquid-liquid process. Hence, SYNEXTRACT will try to implement these discoveries in a Solid-liquid extraction process based on Simulated Moving Bed Chromatography. Such process would complement nicely the liquid-liquid one. Indeed, in case of success, it would not only represent a new approach in chromatography, but it would also enable highly flexible purification processes for REEs containing waste streams, that can easily be adapted to various waste stream lixiviates. Due to the high selectivity, it could even be applied to low REE concentration lixiviates. The process flexibility is one of the main bottleneck to enable their recycling as the research and development cost currently necessary to adapt current liquid-liquid extraction processes prohibits it. It should also be mentioned that SYNEXTRACT process would be all aqueous, therefore avoid the use of organic solvent and would drastically reduce process wastes and running costs.

Keywords: rare earth,recycling,process,extractant,chromatography
Companion Nanodiagnostics for Quantifying EPR and Stratifying Patients to Targeted Nanotherapies (CONQUEST)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-01-01
End date: 2017-06-30
Duration (months): 18.0
Total project cost (EUR): 145312.0
EU funding (EUR): 145312.0
Participants: 1
Project status: CLOSED

CONQUEST aims to commercialise a first-of-its-kind platform technology for imaging a biological effect – i.e. the EPR effect – that is predictive for a cancer patient's response to tumor-targeted nanomedicine (NM) therapy. CONQUEST thereby addresses a key issue in the (nano)pharmaceutical industry; as currently large proportions of cancer patients do not respond to NM, while others show major improvements in terms of response rates, survival times and quality of life. This trend impairs the outcome of clinical studies and results in many patients receiving treatments that are not effective to them. It would therefore be highly desirable to stratify responders from non-responders prior to study entry or treatment. CONQUEST stands at the basis of introducing a solution to this problem in the pharmaceutical industry. Prof. Lammers and colleagues, as part of ERC-funded research, have developed a powerful imaging approach that allows to construct an EPR profile of each individual tumour - by the administration and non-invasive imaging of contrast agent-labelled nanocarriers (drug-loaded or empty) that accumulate in tumours through EPR. The general idea is that patients with a low degree of EPR, and therefore unlikely to respond to such treatments, can be excluded from NM treatment and referred to alternative established or experimental interventions. Vice versa, patients with a high level of EPR can likely be treated relatively efficiently. Recognising the commercial potential of this technology, CONQUEST aims to tailor the technique and protocol for application in humans, by tuning the method for imaging with PET-MRI. A successful demonstration of PET-MRI-based EPR imaging will trigger large interest of the pharmaceutical and diagnostics industry, to invest in further clinical (co-) development.

Keywords: nanomedicine,epr effect,platform technology,tumor targeting,imaging,pet mri
Trusted online service for identity assurance (IDAaaS)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Norway
Call: Engaging SMEs in security research and development (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-10-01
End date: 2017-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The objective of the overall innovation project is to commercialize a trusted online service for identity assurance (IDAaaS - Identity Assurance as a Service). This service will be implemented according to European standards for electronic identity, including eIDAS and STORK. The new service will be based on several years of development of secure electronic identity and digital signatures in the Nordic market. The expected outcome will be a simplified and cost effective online service for identity assurance that can be used in regulated industries such as banks and financial institutions (hereafter referred to as banks). The purpose of the service will be to assure that a user is who she claims to be when signing up to a new online service. The lack of good solutions for trusted digital on-boarding of customers makes it difficult for new online-only players to enter the market, which could otherwise increase competition and improve the bank services in general. Large costs, trouble and hassle for both the bank client and the bank hamper innovation in the finance sector. Electronic identity is a prerequisite for digital on-boarding. The electronic identity in Europe is fragmented and the missing implementation of European standards in this field represents a major barrier to secure cross-country transactions. The problem of establishing the true identity of the onboarding customer must be solved using multiple tools and instruments. This tool box of multiple tools is the innovation of Signicat’s solution.

Keywords: identity assurance,electronic identity
The Normative and Moral Foundations of Group Agency (Group Agency)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Austria
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-12-01
End date: 2023-05-31
Duration (months): 66.0
Total project cost (EUR): 2495190.99
EU funding (EUR): 2495190.99
Participants: 1
Project status: CLOSED

Though philosophers have debated intensely the issue of group agency in the last years, little scholarly work has yet been done on the normative constitution of group agents. The present project will fill this lacuna in a groundbreaking way. A philosophical analysis of the constitutive conditions of individual and collective agency will be combined with recent research in moral philosophy, legal theory and economic theory on the organisational structure of institutional agency. The first aim of the project is to provide a detailed philosophical investigation of the normative foundations of group agency and to work out the rational and moral norms that constitute and guide group agents. The second aim is to explore the implications of such an analysis for moral and legal philosophy. The third aim of the project is to apply the philosophical results to a normative analysis of corporate and economic agents. The main objectives of this project are: (1) To analyse the constitutive and regulative rules of group agency and their impact on the normative identity and self-understanding of associative as well as institutional group agents. (2) To investigate the consequences of philosophical work on group agency for recent theorising in moral and legal philosophy. (3) To explore how the achieved philosophical results can help advance a normative understanding of group agents with a clear organisational structure such as corporate and economic agents. The results will give us a new understanding of group agency, but will also have an impact on debates about the concept of agency in moral philosophy, legal philosophy, and philosophy of economics. Methodologically, the project will cover philosophy of action, moral philosophy, legal theory, philosophy of economics, and organisation theory. The project will also have an impact on wider debates about normative orders in general and the normative framework and structure of social, political and economic institutions.

Keywords: group agency,normativity,constitutivism,collective moral agency,legal theory,normative frameworks of institutions,corporate agents,economic agents
Non-invasive decoding of brain communication patterns to ease motor restoration after stroke (BCINET)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: France,France
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-10-01
End date: 2026-09-30
Duration (months): 72.0
Total project cost (EUR): 1999720.0
EU funding (EUR): 1690220.0
Participants: 2
Project status: SIGNED

Human-computer interfaces are increasingly explored to facilitate interaction with the external world. Brain-computer interfaces (BCIs), bypassing the skeletomuscular system, are particularly promising for assisting paralyzed people in control and communication, but also for boosting neuromotor rehabilitation. Despite their potential, the societal impact of BCIs is dramatically limited by the poor usability in real-life applications. While many solutions have been proposed - from the identification of the best classification algorithm to the type of sensory feedback - the accuracy is still highly variable across subjects and BCIs cannot be used by everyone. Critically, these approaches have implicitly assumed that the user’s intent could be decoded by examining the activity of single brain areas. Today, we know that this is not true as the brain functioning essentially depends on a complex network of interactions between differently specialized areas. The grand challenge of this project is to develop a novel generation of BCIs that integrate the user’s brain network information for enhancing accuracy and usability. Based on this approach, we will experiment innovative BCI prototypes to restore the lost motor functions in patients suffering from stroke. This project relies on a unifying framework that analyses and models brain networks by means of analytical tools derived from graph theory and complex systems science. By recruiting diverse neuroimaging and experimental methods, within a modern computational framework, we aim to i) identify new control features for enhancing BCI accuracy, ii) study the brain dynamics of human learning for improving adaptive BCI architectures, and iii) optimize brain stimulation techniques for boosting BCI skill acquisition. This project can significantly improve BCI usability as well as determining how brain lesions compromise brain functioning and which solutions are most effective to unlock motor restoration after stroke.

Keywords: brain computer interfaces,complex networks,stroke rehabilitation
Multi-spectral remote system for real-time alarm and monitoring of natural hazards (SENTINEL)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Techcom Srl was founded in Italy in 2017 with the aim to design and develop environmental monitoring solutions, providing installation and maintenance service for landslides, debris flows, sudden floods, avalanches, glaciers, etc. Over the past 10 years, our team of engineers and expert physicists have developed products and solutions based on the latest sensing technologies and integrated with our in-house software to serve customers with a high level of customization. We have evolved throughout the years performing >100 land monitoring projects with national and international scope reaching >50 active sites in 5 countries. With the ambition to continuously provide solution to monitor territories with new disruptive technologies that will result in more accurate detection for the natural hazards, we seek to bring to the European market a new revolutionising monitoring system. Our innovation, SENTINEL, consists of a single device that integrates: (1) 3 complementary sensing technologies that allow optimum performance and coverage under any light and weather condition; (2) Artificial Intelligence software that delivers real-time decision support and action response adapted to the risk severity; and (3) data portal that is accessible on all devices with 24/7 live stream transmission to customers and interaction with local authorities and decision makers. SENTINEL reduces by 75% equipment costs and 25% maintenance costs, gives ≥90% accuracy and fastness, and provides recommendations based on AI to allow customers (e.g. local and regional municipals, civil protection, railways, ski resorts) to rapidly detect and give an alert response within seconds, thus guaranteeing security and safety at all time. SENTINEL will bring our company international expansion and growth, reaching +€11.07M in revenues by 2026 while creating 22 jobs 5 years after market launch.

Keywords: natural disasters,natural hazard monitoring,emergency management,remote monitoring system,multi spectral,sensing technologies,artificial intelligence
Synthetic Biology for Architecture (Synbio4Arch)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Coordination and support actions
Countries involved: Italy
Call: FET Innovation Launchpad (H2020-FETOPEN-2018-2019-2020-03, 2019)
Start date: 2020-09-01
End date: 2021-08-31
Duration (months): 12.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Synbio4Arch intends to leverage the foreground generated in the FET project LIAR to develop a synthetic biology toolkit for architecture. The envisaged technology will allow engineers and architects to leverage microbes to embed distributed biomanufacturing, on-site domestic waste treatment and CO2 capturing into buildings. The innovation will consist in a cloud-based application that allows architects and engineers to select microbial strains engineered with pre-made and validated synthetic metabolic pathways relevant for household wastewater management such as organic compound oxidation and inorganic phosphate recycling. The innovation will allow practitioners in the construction field (such as engineers and architects) with little expertise in molecular biology to access the power of synthetic biology. Toward this aim, this launchpad proposal aims to assess regulatory barrier and develop a commercialization plan to exploit Explora’s proprietary doulix platform developed within the framework of the LIAR project.

Keywords: living architecture,synthetic biology,non conventional applications,green buildings,domestic wastewater,treatment