Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
HOMER - Development of Home Rehabilitation system (Homer)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: SME instrument
Countries involved: Slovenia
Call: Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-12-01
End date: 2017-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Kinestica, an R&D oriented SME founded by a team of experts in biomedical and rehabilitation engineering with 50 years of combined experience, has developed disruptive TRL7 solution that will revolutionize the field of post stroke rehabilitation and home care. Stroke affects 15 million people around the world annually. More than 75% of stroke survivors are left without proper rehabilitation in the most crucial stages of the recovery. In EU alone, cost of stroke is estimated at €38 billion. HOMER project (HOME Rehabilitation) will be first-ever open-access rehabilitation system to integrate patented motion capture technology with virtual reality and open-source ICT platform to provide accessible and cost-effective solution. HOMER will extend limited rehabilitation patients normally receive and thus drastically improve rehabilitation therapy outcomes for large number of stroke patients. It will be 10 times more affordable than current state-of-the-art systems available on the market. HOMER addresses challenges laid down in eHealth Action Plan 2012-2020 and helps to overcome current gaps in exploitation of promising research results in ICT for Health, Well-being and Ageing well. Commercialization of HOMER will include several channels. For initial launch we will collaborate with existing partners and distributors of our clinical rehabilitation solutions. We will engage rehabilitation institutions already using our clinical devices to help promote Homer. Later direct sales channels through internet, company branches and franchises will be included. The strategy will enable us to reach large populations of stroke patients in need for effective and affordable rehabilitation solution. HOMER promotes excellent science and encourages innovation, thus contributes to multiple EU and global challenges and EU industry policy. HOMER will create 120 new employments in Kinestica and open new opportunities for EU SMEs. Most important it will improve life quality of many EU citizens.

Keywords: stroke rehabilitation
Milk quality antibiotics sensor (MILQAS)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: SME instrument
Countries involved: Denmark
Call: Stimulating the innovation potential of SMEs for sustainable and competitive agriculture, forestry, agri-food and bio-based sectors (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-05-01
End date: 2019-03-31
Duration (months): 35.0
Total project cost (EUR): 1429250.0
EU funding (EUR): 1000475.0
Participants: 1
Project status: CLOSED

With the project MILQAS (Milk quality antibiotics sensor), PlastiSens ApS brings a patented biosensor on the market. A novel testing device that meets a major need for reducing the waste of raw milk in the value chain. Every day truckloads of milk are spoilt by cross-contamination with antibiotic-polluted milk. Today, milk in tankers is analyzed upon arrival at the dairy in a lengthy 1--2 hour process. By then, milk from several farms has already been mixed in the same tank. PlastiSens' technology can in 1-2 minutes, analyze antibiotics in milk before it is loaded onto the truck, thereby potentially saving 80-90% of the cargo from cross contamination. The dairy industry is very strong in Europe, and will therefore be the first target market. The dairy segment alone constitutes a market volume of € 500M. PlastiSens technology can also be adapted to for testing for other contaminants in both liquid and solid samples, and also for analyzing antibiotics in complex samples as milk. The MILQAS project will enable PlastiSens to create a solid revenue stream of nearly € 6M with the sale of analysis instruments and single-use test kits (chips) within two years after conclusion of the project. Arla A/S, the 7th largest diary company in the world, has agreed to test our technology on milk trucks and at selected milk producing farms. We use selected subcontractors for 3th party validation and expect that the project will create an extra 50 full time jobs. 30 jobs will be created at PlastSens and about 20 at our European sub-suppliers. Ten years from now, we envisage revenues around € 100M and 80-100 employees.

Keywords: food waste,biosensor,agriculture,antibiotics detection,in line testing
Quantitative insight into chromatin nanoscale structure: sub-nuclear organisation of oncoprotein DEK (qCHROMDEK)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-12-01
End date: 2021-11-30
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: CLOSED

DEK protein is a chromatin architectural factor which has been consistently associated with tumour progression. Its expression level differs between normal and cancer cells, raising the possibility of using DEK as a tumour marker. On the other hand, super-resolution imaging revealed recently that nucleosomes can form discrete groups called "clutches" of various dimensions and densities. However, the quantitative analysis of the connection between proteins playing chromatin architectural role and nucleosome clutches has not been yet deciphered. Within this project, I hypothesize that there is a correlation between the organisation of DEK oncoprotein and the local chromatin structure related to the proliferation level of cells. The overall aim of the proposed work is to provide a more precise, quantitative understanding of possible connection between DEK expression level and local chromatin structures and by that to gain the additional information about DEK role in cancer. This project will take advantage of cutting-edge biophysical tool such as DNA origami, single-molecule localisation microscopy and cellular biology. Experimental design is based on the construction and application of a bi-dimentional DNA origami to calibrate and mimic subnuclear structures. The quantitative approach will rely on STochastic Optical Reconstruction Microscopy (STORM). This study will be done using normal cells with different level of proliferation and cancer cells with different level of malignancy. Finding the relation between DEK expression, connected to the proliferation level of normal and cancer cells, and the number of nucleosomes per clutch could improve the comprehension of chromatin organisation role in different levels of tumorigenesis. Quantitative insight to the number of nucleosomes per clutch in relation to the level of cell proliferation could be in the future an input for a precise recognition of cancer in the early stage of tumorigenesis.

Keywords: super resolution microscopy,dek protein,chromatin organisation,nucleosomes,oncoprotein
Nordic Energy Efficiency Mortgages (NEEM)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Switzerland,Belgium,Finland,Sweden,Denmark,Denmark
Call: Financing for energy efficiency investments - Smart Finance for Smart Buildings (H2020-LC-SC3-EE-2020-2, 2020)
Start date: 2021-06-01
End date: 2023-05-31
Duration (months): 24.0
Total project cost (EUR): 1485000.0
EU funding (EUR): 1485000.0
Participants: 8
Project status: SIGNED

The EU green deal and ambitious climate targets of the Nordic governments require massive private investments into energy efficiency of the Nordic building stock, electrification of heating and smart energy systems. Though a substantial part of the needed investments is profitable on paper, they are not actually carried out – an issue labelled the energy efficiency gap. For example, high transaction costs as a result of many points of contacts and lack of intuitive information makes energy renovations complex and unattractive for households. Also, lack of data hampers identification of buildings, which are ripe for energy efficiency renovations. A common denominator for the barriers is that financial institutions are in a perfect position to overcome them, through their touchpoint with end customers and ability to finance the investments. In this project, we will develop and market test concrete solutions to support Nordic financial institutions in overcoming the barriers. In concrete, we will do this by setting up a Nordic hub for Energy Efficient Mortgages, allowing us to leverage the already developed solutions within the initiative and previous research to which many consortium partners have contributed. The developed solutions will be demonstrated and tested in the market by Nordea, Swedbank and Hemma. The ultimate output of the project will be so-called blueprints for financial institutions on how to implement solutions to overcome the identified main barriers to energy renovations. This will be advanced throughout the Nordic banking sector through a comprehensive outreach campaign. The blueprints will showcase the value of a full-scale implementation to financial institutions as they are based on empirical tests within internal systems and response by end-customers. Thus, the blueprints will serve as a script to financial institutions to kick-start the much-needed renovation wave to be on track with the EU green deal as well as national climate targets.

Keywords: energy efficiency,mortgage lending,sustainable finance,asset screening,risk management,prudential framework,capital markets union,basel committee,behavioral science,covered bonds,energy data
The Water Cultures of Italy, 1500-1900 (Water-Cultures)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Italy,United Kingdom
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-10-01
End date: 2025-09-30
Duration (months): 72.0
Total project cost (EUR): 2444549.0
EU funding (EUR): 2433520.25
Participants: 2
Project status: SIGNED

Behind this project lies a paradox: water, although vital for life, has historically had little intrinsic value. Considered base and common as a drink, it was nevertheless the most symbolically charged of the elements; of limited monetary value in and of itself, access to it was in fact hard-fought, the foundation and driving force of society. The Water Cultures project aims to create a new field of study, based around the social and cultural history of a people’s polyvalent interactions with water, applicable to a wide range of places and times. The project proposes an epistemological method of structuring, analysing and presenting the diverse range of findings and approaches into a new holistic understanding. The Water Cultures concept is based on the synergistic braiding of five key 'Streams': the symbolic beliefs and practices associated with water; the circulation and evolution of knowledge about water and disease and its effects; the water management systems of large cities and demands on them; the changing hydraulic landscape of rural areas; and the occupations of water, exploring the professions and trades associated with water and its delivery and uses. Italy has been chosen as the case study—for its rich archives and social, political and geographical variety. The Italian history of water, from the 1500s to the end of the 19th century, is a story of authority and conflict, social hierarchy and material realities, changing medical and scientific knowledge and technological expertise, and religious beliefs and practices. Yet Italian historians have undervalued water and its uses. This transformative project conceptualises a new way of writing history, with water at its core. It proposes the history and culture of a given society, the construction of identities and forms of self-representation based on relationships and interactions with water: the ways of controlling, using and conceiving it, and the symbolic, creative and material dimensions it assumed.

Keywords: water and the sacred,thermal springs,mineral waters,water and health,disease,cholera,sanitation,hydraulic systems and infrastructure,water supply management,water access,irrigation and land reclamation,water related occupations,circulation of hydrological knowledge and expertise,social and cultural history,environmental history,architectural history,history of medicine,science and technology,hydraulic archaeology,landscape archaeology,social and cultural his
Feasibility analysis for the development and market introduction of an innovative and multi-functional façade. (KlimaFacade)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Business case and Customer Pain Point: In order to fulfil all existing and upcoming EU legislation on the use of RE, rainwater retention and a minimum percentage of green areas, construction companies, architects and property developers need to use all opportunities of the building structure (roof and façades). In the last years, the use of roof areas has been developed quickly leaving the façade the last unused potential for innovations. The global vertical garden construction market is expected to growth at an annual rate > 11 %, (i.e., global market € 6.8 billion in 2017 for green roofs and façades). The green building materials market was valued at around USD 127.5 billion in 2014 and is expected to reach USD 255 billion in 2020, growing at a CAGR of around 12%. Taking into account the present situation, our SME Kre_Ta has successfully developed KlimaFaçade. It is a multi-functional and self-operating façade module, which gives our customers a unique flexibility to design a functional building skin. The basic structure can be combined with standard photovoltaic panels or with plant (green) modules. KlimaFaçade is certified and can be installed on all existing types of substructures. Road-To-Market: KlimaFaçade is currently at TRL 6. We are planning to start commercialising KlimaFaçade by 2021. Our module will be intensively tested by internal and external specialists to ensure high quality standards. Our system will be installed in three pilots and the gained knowledge will lead to the certification and IPR protection phase, prior to market entry. Business Model: KlimaFaçade commercialization will generate high revenues with a targeted market share of 20%. KlimaFaçade is the first smart and multi-functional façade on the market and will push and diversify our revenue streams. We expect to sell more than 35.000 m2 façade generating additional revenue streams of 18.5 M€ for our company from 2019-2025 as well as to triple our workforce by 2025.

Keywords: green facades,smart buildings,urban climate,multi functional building surfaces
LEveraging WInd-Assisted THrust (LEWIATH)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-01-01
End date: 2019-04-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Maritime transport dominates global freight transportation with 58,500 vessels totaling covering 90% of global goods trade. Marine propulsion market is expected to grow at a CAGR worth 4.3% to reach $18 Billion by 2026. Climate change imperatives and rising environmental awareness force governments to tighten legislation and set pressure on shipyards and shipowners to develop greener alternatives. Therefore, market potential for wind propulsion technologies for shipping vessels is estimated to reach between 3,700 and 10,700 deployed systems between 2020 and 2030 for both retrofit and installation on newbuild vessels. CWS is a family story which was incorporated in 2016 to revive commercial sailing. CWS relies on sail automation, mechanical processes miniaturization and IT technologies to fix disadvantages which led to disappearance of commercial sailing vessels one century ago. Our patented technology is inspired by aeronautics and combines (1) Reversible rigs, (2) Telescopic and free-rotating masts and (3) Wing-sail automation. Our technology pays itself back in 4 years only at current bunker fuel price (≈ €570 / ton) and would generate a yearly €570,000 savings on fuel consumption per wing-sail. Global Sulphur Cap 2020, GHG emission reductions set by the International Maritime Organization and future eco-friendly dis/incentives measures will entice shipping industry using less polluting and more expansive fuels (Biodiesel, LNG, Fuel cell Hydrogen, Battery) and therefore, RoI associated with our wind-based technology will constantly increase over time. Moreover, 300 wing-sail systems are deployed on a scale of 100 vessels would reduce CO2 emission by 1 million tons a year. SMEI Phase 1 aims at: carrying out aerodynamics studies, finalizing mechanical engineering of Prototype V3, extend geographical coverage of IPR, and carrying out a market study. We are already supported by leading shipowners worldwide to have our technology test in full scale by 2020.

Keywords: sailing,reversible rigs,freestanding rotational masts,automation,shipping,hybrid propulsion system,container ships,tankers,wind
Tailoring the functional Capacity of Cytotoxic T cells for future Therapies (ToCCaTa)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-10-01
End date: 2023-09-30
Duration (months): 60.0
Total project cost (EUR): 1999850.0
EU funding (EUR): 1999850.0
Participants: 1
Project status: SIGNED

Cytotoxic T cells have enormous potential for prophylactic and therapeutic interventions against problematic acute or chronic infections and against malignant tumors. A major obstacle to utilizing them effectively is our limited understanding of the molecular foundation that is necessary for CD8 T cells to fulfil their pleiotropic functions. Equally important is to find solutions supporting the robust and safe induction of large numbers of pathogen- or tumor-specific T cells and strategies for customized generation of T cells equipped with a functional capacity that are optimized to the often contrasting needs of particular diseases. For instance, anti-tumor immunity requires large numbers of highly activated effector T cells, while resting memory cells with high proliferative potential in combination with tissue-resident memory cells are thought to enhance protection against viral infections. Similarly, the challenge in treating chronic infections and tumors is to overcome the hypo-functional “exhausted” stage of T cells, but therapeutic induction of the same mechanisms to attenuate an aggressive T cell response could be vital for treating autoimmunity or immunopathology in fulminant liver or lung infections. Thus, to develop prophylactic or interventional strategies through which qualitative aspects of T cell function can be adjusted is a current key challenge in the immunotherapy and vaccine field. We seek to promote such activities by performing research that aims to significantly augment our comprehension of how molecular particularities translate into functional diversity. By taking advantage of 1) experimental systems that specifically mimic disease relevant T cell phenotypes, 2) approaches to assess molecular diversity at single cell level, 3) effective strategies to alter gene expression, and 4) systematic and hypothesis-driven molecular screening, we anticipate the discovery of new targets to optimize immunotherapies for tumors and chronic infections.
Next Generation Platform as a Service (NGPaaS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Partnership: 5G PPP (cPPP)
Countries involved: Italy,Spain,Israel,Belgium,France,France,France,France,Denmark,United Kingdom,Gibraltar
Call: 5G PPP Convergent Technologies (H2020-ICT-2016-2, 2016)
Start date: 2017-06-01
End date: 2019-08-31
Duration (months): 27.0
Total project cost (EUR): 6646352.94
EU funding (EUR): 5214705.63
Participants: 13
Project status: CLOSED

Cloud innovations have had a major impact on the IT industry but not yet on networks. The danger is that 5G will be a niche industry providing basic connectivity for the cloud applications and services boom. The NGPaaS project envisages 5G as: a build-to-order platform, with components, features and performance tailored to a particular use case; developed through a “Dev-for-Operations” model that extends the IT industry’s DevOps approach to support a multi-sided platform between operators, vendors and verticals; and with revised Operational and Business Support Systems (OSS/BSS) to reflect the new parameters and highly dynamic environment. NGPaaS can enable 5G to become central to a cooperative future with cloud developers, by removing the technological silos between the telco and IT industries. NGPaaS builds on 5G-PPP phase 1 projects and lays the foundation for large-scale phase 3 deployments and industrial usage, through a stepped validation of several Telco, IoT/vertical and combined scenarios culminating in a live test in Paris-Saclay campus that can incorporate innovative SMEs selected for showcasing NGPaaS’s operational, service and business benefits.

Keywords: cloud,carrier grade orchestration,virtualization,devops,platform as a service