Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Carbonyl sulfide and sun-induced fluorescence as joint constraints on terrestrial carbon cycling (COSIF)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-01-01
End date: 2019-12-31
Duration (months): 24.0
Total project cost (EUR): 166156.8
EU funding (EUR): 166156.8
Participants: 1
Project status: CLOSED

The terrestrial biosphere annually absorbs around one quarter of the carbon dioxide emitted by human activities each year and thus beneficially decreases the rate of global warming. The sign and magnitude of the net land carbon dioxide flux is determined by the delicate balance between two key carbon cycle processes: gross primary productivity (photosynthetic carbon uptake by land plants) and ecosystem respiration (carbon dioxide production by all living things). The magnitude of both processes is however highly uncertain due to conceptual and methodological difficulties in disentangling the two from the (measurable) net carbon dioxide flux. This uncertainty undermines our ability to project the future of the terrestrial global carbon cycle, which in turn severely impedes the conception of realistic carbon emission reduction measures allowing constraining global warming below agreed targets. The overarching objective of the proposed project is to provide new constraints on gross primary productivity and ecosystem respiration using a dual-constraints approach. Gross primary productivity and ecosystem respiration will be estimated jointly by ecosystem-scale carbonyl sulfide eddy covariance and sun-induced fluorescence measurements at three contrasting European ecosystems. The resulting data will then be used in a unifying modelling framework allowing gross primary productivity and ecosystem respiration to be determined with much greater confidence based on the dual constraints by the experimental measurements.

Keywords: gross primary productivity,ecosystem respiration,eddy covariance,proximal sensing,modelling
Industrial Strategy and Competitiveness Studies at TalTech (TALTECH INDUSTRIAL)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Italy,Estonia,Finland,United Kingdom
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2020-10-01
End date: 2024-06-30
Duration (months): 45.0
Total project cost (EUR): 899600.0
EU funding (EUR): 899600.0
Participants: 4
Project status: SIGNED

The overall objective of the TALTECH INDUSTRIAL project is to strengthen the research excellence of Tallinn University of Technology, Estonia, in the fields of (1) industrial strategy and competitiveness studies, and (2) advanced data analytics skills to be exploited to conduct improved analysis of global value chains and clusters, and to identify and analyse the impact of relevant public policies through cooperation with international partner institutions in the EU. To reach this objective, TALTECH INDUSTRIAL will bolster a strategic partnership between TalTech as the beneficiary, and Bocconi University (Italy), Aalto University (Finland) and NESTA (United Kingdom) as the key knowledge providers. The network will develop a lasting partnership that will sustain after the project and focus on building capacities to empower TalTech and its regional partners to assist the design of industrial strategy both at home and elsewhere in the EU cohesion regions. The network will allow (1) to co-create more socially-relevant research that will benefit industrialists, policy makers and entrepreneurs; and will (2) foster policy learning and the development of more effective policies that meet the needs and expectations of the society; and (3) establish executive training system for improving the accessibility of the cutting-edge research for businesses and policy makers. The TALTECH INDUSTRIAL project brings TalTech together with top 1% research and policy analysis actors in the field and will implement a demand-driven capacity building strategy that will enhance the research capacity of the participating organisations, boost the career of ESRs, and establish TalTech as a regional research hub. The key innovative aspect of TALTECH INDUSTRIAL is that it focusses on emerging new research areas, new data and research methods of very high industrial and policy relevance, where TalTech and partners are well established to take the lead in Europe.

Keywords: cluster evolution,catching up dynamics,4th industrial revolution,global value chains,applied data science
General-purpose Robot for Object-retrieval in Warehouses (GROW)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Coordination and support actions
Countries involved: Italy,Italy
Call: FET Innovation Launchpad (H2020-FETOPEN-2018-2019-2020-4, 2020)
Start date: 2021-09-01
End date: 2023-02-28
Duration (months): 18.0
Total project cost (EUR): 126373.21
EU funding (EUR): 100000.0
Participants: 3
Project status: CLOSED

The current boom in e-commerce is challenging the logistics industry because shipment volumes are growing rapidly and online retail typically requires more logistical work per item compared to traditional brick and mortar retail. Manual picking is currently preferred when the number and variety of objects increases because automation becomes increasingly challenging. The specific need addressed in the project is the robot-based automatic collection of sets of small objects in weakly-engineered warehouses. The goal of the project is to address this need by the realisation of the innovation potential of the GOAL-Robots FET project technology applied to industry-relevant warehouse environments. In particular, the project will show that the “open-ended autonomous learning” technology developed within the GOAL-Robots project allows the creation of general-purpose robots for object-retrieval capable of autonomously learning to reach, grasp, and collect a large variety of objects, independently of their shape, rigidity, position, and orientation on shelves. This technological transfer will be achieved through three objectives: (a) the implementation of a demonstrator to show the potential of the technology to the target stakeholders; (b) the technology assessment of the GROW solution involving relevant stakeholders and partners for technology transfer, validating the innovation and its commercial viability; (c) the development of the business case and plan, the dissemination of the solution, and the preparation of communication material to reach potential stakeholders and support the implementation of an effective marketing strategy.

Keywords: autonomous robot,artificial intelligence,warehouse logistics,weakly engineered environments,demonstrator,stakeholder reaching
Reconstructing hybridization events between sea turtle species separated by 30 million years: genomic patterns and evolutionary consequences (TurtleHyb)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-10-01
End date: 2022-05-28
Duration (months): 24.0
Total project cost (EUR): 183473.28
EU funding (EUR): 183473.28
Participants: 1
Project status: CLOSED

Hawksbills and Loggerheads are two endangered sea turtles species that separated approximately 30 million years ago. Despite this very long divergence time, they are currently hybridizing on the Brazilian coast. Among nesting females morphologically identified as Hawksbills, 42% are F1 hybrids. Hybrids can backcross with both parental species and produce viable offspring. This appears to be a beautiful natural experiment, possibly driven by population decline that favour interspecific mating, to study and understand species hybridization under the extreme conditions of secondary contacts between highly divergent genomes. Here I propose to study causes and consequences of the hybridization in Loggerhead and Hawksbill sea turtles using both whole genomes and RAD sequencing data. I will a) infer timing and intensity of putative ancient hybridization events that may have also occurred in the past, and their relationship with the population size dynamic. Then I will b) dissect the current hybridization event occurring in Brazil, looking for genomic regions associated with reproductive isolation and incompatibilities, and for segregation distortion along the genomes in hybrids parents and hatchlings. The amount of data generated will be unprecedented for sea turtles, will be helpful to identify risks and evolution opportunities of the hybridization process in these turtle species, and will contribute to the general understanding of species hybridization and its genomic aspects. The proposal includes transfer of knowledge to the host institution and the training of the candidate in innovative genomic and statistical techniques. Results will also strengthen the collaborative network of researchers in Europe and the Americas studying sea turtles and their hybridization. This project is in line with current European guidelines to increase knowledge of marine wildlife to protect the environment and adapt to climate change.

Keywords: sea turtles,hybridization,genomes
The genetic basis for glial differentiation in the developing zebrafish retina. (Glial Patterning)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Glia far out number neurons in the brain and their defects are now known to be associated with many neurological diseases. Glial specification and physiological function are very well studied however, remarkably little is known about they way in which glia are positioned or shaped in order to perform their critical support functions. The goal of the present study is to broaden the field of glial development by using new techniques to ask previously unattainable questions. This central goal of this research project is carried out through an in-depth morphological, genetic and transcritpomic analyses of differentiating Müller Glia in the Zebrafish (Danio rerio) eye. Results from these studies will provide and the first extensive profiling of a differentiating glial population. Furthermore, the extensive data that will be generated in this proposal will provide a basis for many future studies on glial biology for both in the host laboratory and for the experienced researcher during his career development. Ultimately, these and future studies will provide a foundation for identifying the molecular networks that underlie glial patterning in the brain that will no doubt be informative in the study of glial related neurological disease.

Keywords: transcriptomics,reverse genetics,crispr
Galileo based inshore-VMS for fisheries (GALiVMS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: SME instrument
Countries involved: Slovenia
Call: SME Instrument (H2020-SMEINST-1-2014, 2014)
Start date: 2015-04-01
End date: 2015-09-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Main objective of the project is to develop Galileo based inshore VMS – Vessel Monitoring System, tailored to monitor artisanal inshore fishing vessels that would enable National Fishery Authorities to monitor fishing vessels and at the same time increase fisherman security when on the sea. General concept of the project is to bring the cost of the VMS device down and bring the security of an “always-ready” satellite-based distress button. The approach will take advantage of Galileo SAR and PRS services and authentication. Proposed solution will consist of two main parts namely on-board terminal and land based TDS-Telematics Data Server. Our solution is beyond the state-of-the-art of existing VMS systems as there is no commercial solution for these problems on the market yet. The novelty of this project lies in the first-of-its-kind integration of SAR services coupled with the Galileo constellation advantages into a product that fits requirements for the inshore VMS. The most important innovations will be only one single device, lower cost technologies, a new compact antenna and authentication and jamming/spoofing elimination. Solution is oriented on the market, institutionally controlled by EU Fisheries Policy, which is represented by owners of a very big number of small fishing vessels. Project results will fulfil the needs of reformed EU Common Fisheries Policy and National Fishing Authorities to enable control of small fishing vessels and the needs of small fishermen to secure their safety. European value added of the project is reflected in important economic benefits, as it will have impact on efficiency of EU Common Fisheries Policy and costs and safety of artisanal fishermen with very important environmental impact on European level and wider. Feasibility study will address institutional, marketing, technical, IPR and regulatory issues, resulting in business plan, which will include projection of sales, financial projections, business indicators and ratios

Keywords: galileo,sar services,prs services,eu common fisheries policy,vmc vessel monitoring system,galileo based vms services,authentication,artisanal inshore fishing vessels,inshore vms
Dissecting and targeting ubiquitin networks in the course of bacterial infections (Ub-BAC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Germany
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-07-01
End date: 2022-06-30
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Ubiquitination represents one of the most versatile post-translational modifications in eukaryotes and is involved in regulation of numerous cellular processes. Despite prokaryotes lacking this system, facultative intracellular bacteria like Salmonella, Shigella and Legionella have evolved multiple strategies to manipulate the host ubiquitin (Ub) system to their own benefit. This proposal is focussed on gaining a fundamental understanding of the Ub system in the course of bacterial infections. We will employ advanced quantitative proteomics to perform a global analysis of the dynamic changes in the ubiquitinome and phosphoproteome of epithelial cells and macrophages upon infection with Salmonella, Shigella and Legionella. The comprehensive datasets will constitute an invaluable resource freely available to the scientific community. We expect to identify novel pathways triggered by selected bacterial ligases and will characterise their contribution to pathogenicity and virulence, as well as their suitability for being targeted in a therapeutic setting. Both medicinal chemistry and structural biology approaches will be exploited to identify inhibitors for NEL-type bacterial ligases. Hypothesis-driven projects within the work program focus on (i) a novel chemical modification of Ub controlling Legionella infections and (ii) the observation that Ub chains on Salmonella can form nanoscale clusters that recruit and activate multiple signalling pathways within the host cell. Super-resolution microscopy and single-molecule imaging will be used to visualise and dissect these Ub-triggered complexes. Taken together, the combination of unbiased global proteome analysis and hypothesis-driven projects creates a unique scientific program within the biomedical field of understanding and combatting bacterial infections. Along the same lines, this proposal holds a great potential for the future development of novel strategies for antibacterial therapies.

Keywords: salmonella,shigella,legionella,bacterial effectors,ubiquitination,ubiquitinome,phosphoproteome,e3 ligase,drug development,host pathogen interaction,innate immunity,autophagy
Industrial GHz repetition rate, burst mode, ultrashort pulsed fiber laser for high speed volume-ablation micromachining applications (GHZ-BURST)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Türkiye
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

USP lasers (ultrashort pulsed lasers) - a specific type of laser- enable high precision processing without any heat effect on the material. Their usage in many industrial and scientific markets is increasing rapidly resulting a market growth stands at between 20 and 25 percent per year. USP lasers have the potential to dominate the market with their sophisticated and extraordinary abilities. Despite the pristine quality they deliver, ultrashort pulsed processes often have the reputation of being “too slow” and therefore are not suitable for industrial-grade applications. However, to fulfil current and future customer needs in the USP laser micromachining market, faster processing time is critical. We developed GHZ-BURST that removes the speed problems and the negative effects of current lasers on the production processes and on the products. We proudly announce that our game changer USP fiber lasers have up to 1000X higher processing speed ability while maintaining high precision within manufacturing operations in comparison to other USP lasers available in the market. Also, GHZ-BURST can be integrated into mass production easily. Our method is based on ablation-cooling of materials during the micromachining process. We obtain 10 times more level of ablation with 200 times less pulse energy. Our innovative method was published in most prestigious academic magazine (Nature) and it is the only article that is found worthy of publishing in Nature about USP laser operating regimes in the last decade. Recently, in the exhibitions and fairs we participated in Germany and the US, the need for the functional features of GHZ-BURST were approved by above 50 integrator companies. These companies revealed their interest to buy our product and demanded demo laser when it is ready. We aim to carry the demo of GHZ-BURST to potential customers for trials and demonstrations, and to laser machine integrators to try for different applications on different sectors.

Keywords: ultrashort pulsed fiber laser high speed volume ablation micromachining material processing femtosecond precision pulse energy
Smart Planning and Virtual Certification (PLASA-2)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: European rail initiative
Action type: Research and Innovation actions
Partnership: Shift2Rail (Art-187)
Countries involved: Germany,Germany,Germany,Spain,Germany,Sweden,Sweden,Sweden,France,United Kingdom
Call: Virtual certification & smart planning (H2020-S2RJU-CFM-2018, 2018)
Start date: 2018-09-01
End date: 2020-12-31
Duration (months): 28.0
Total project cost (EUR): 1085214.29
EU funding (EUR): 823643.75
Participants: 12
Project status: CLOSED

In Europe, different and often not perfectly suitable tools are in use today to simulate railway operations. This leads to results which may not be comparable and to a data landscape that has no proper data interfaces between different countries implemented. This renders the simulation of cross-border connections difficult. Moreover, no tool has yet been implemented that is able to simulate large networks and that can also be used for large networks. In PLASA, the concept and a first prototypical implementation for an integrated Smart Planning simulation is being developed, addressing tactical to daily capacity planning. In PLASA-2, a new integrated Smart Planning simulation approach will be developed, which will be capable of analysing entire networks. The possibilities of interplay between microscopic and macroscopic simulation will be particularly evaluated and a concept for applying the PLASA model for capacity analysis will be defined in view of enabling strategic capacity planning to support investment and reinvestment decisions. In the field of Virtual Certification, a reduction of the duration and cost of the process for an appropriate authorisation to put a new train into service is needed. Today, the authorisation process for putting new rolling stock into service is largely based on full-scale field and line tests, which is expensive, time and capacity consuming. A breakthrough in performance can only be made if numerical simulations are progressively introduced in a mixed virtual/experimental authorisation process, resulting in less field tests. In PLASA-2, a very lean structure will be created to coordinate the activities related to virtual certification within the relevant TDs of IP1 and IP2, to define comprehensive practical industrial processes for validation of rolling stock sub-systems/systems. Hence, a common interface with standardisation and regulatory bodies will be proposed to steer the projects outcomes in the standards and guidelines.

Keywords: smart planning,strategic capacity planning,interplay between microscopic and macroscopic simulation,virtual certification,mixed virtual,experimental authorization process