Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Female Cross-Dressing in Early Modern and Modern Japan, 1750's-1940's (FCDEMMJ)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Japan
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-12-01
End date: 2027-11-30
Duration (months): 36.0
Total project cost (EUR): 266318.4
EU funding (EUR): 266318.4
Participants: 3
Project status: SIGNED

The FCDEMMJ project aims at investigating the urban culture of female cross-dressing, i.e. the social movement that revolved around the custom for women to wear the clothes and use the body language and the linguistic characteristics the contemporaneous culture reserved to men, that existed in Japan from the 1750's to the 1940's and of the control strategies Japanese governments and police promoted from the 1830's to the 1940's to forbid the practice. The project is interesting as it proposes the first systematical gender historiographical study of the urban culture of female cross-dressing and the opposing control strategies. The project fills an important gap in the state of the art as the available scientific researches have analysed the phenomenon's gender dimension only in in relation to a very restricted number of highly contextualised case studies, thus producing results whose validity is limited to said case studies. The project aims at filling this gap by exploring the gender dimension of the phenomenon in its entirety. The project has a strong expected scientific impact as it will allow to open a new line of research dedicated to the study of the gender dimension of cross-dressing in Japanese history. The project has also a strong expected societal impact as L.G.T.B. rights organisations will be able to use the research results as an historical analogy to criticise and oppose current policies which restrict the gender expression of women and gender non-conforming individuals. Furthermore, the project will produce a great benefit for my career development as it will help me obtain a tenure-track position and create a chair in Japanese Sexuality and Gender History.

Keywords: gender history,japanese studies,cultural history,social history,cross dressing
New Life for Biowaste as a sustainable Soil Improver (FENIX)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Soil health and food
Destination: Soil health and food
Action type: Innovation actions
Countries involved: Spain,France,Denmark,Greece
Call: Innovations for soil improvement from bio-waste (HORIZON-MISS-2022-SOIL-01, 2022)
Start date: 2023-06-01
End date: 2027-07-31
Duration (months): 50.0
Total project cost (EUR): 3251511.46
EU funding (EUR): 2894851.33
Participants: 9
Project status: SIGNED

With a share of 34 %, bio-waste is the largest single component of municipal waste in the EU. Recycling of bio-waste is key for meeting the EU target to recycle 65 % of municipal waste by 2035. Bio-waste can significantly contribute to a more circular economy, delivering valuable soil-improving material and fertiliser as well as biogas, a source of renewable energy. Biochar is a pure, high carbon form of charcoal, obtained through the pyrolysis of biomass, such as bio-waste. Biochar helps regenerate soils by enhancing water-holding capacity, nutrient uptake, soil fertility stimulating microbial activity and diversity and acts as a carbon sink. However, a lack of understanding and evidence of the agronomic benefits and economic returns mean that biochar faces barriers to become a widespread soil improver. Biogas from anaerobic digestion (AD) is a renewable energy source. Yet the cost of disposal of its effluents (digestates) reduces profitability and uptake of new AD projects, even though the digestate is rich in nutrients and can be used as a biofertilizer. Research shows that the combination of digestate and biochar creates a biofertilizer with increased fertility, improved stability and excellent soil regeneration properties. Furthermore, biochar could be a powerful additive to enhance microbiological activity in AD plants. The FENIX project will optimise Biochar for different soils using AD digestate. FENIX will demonstrate the agronomic and economic returns of its soil improver in field tests (TRL 8) in three countries in the West and South of Europe. FENIX brings together partners that cover the full value chain and with entrepreneurs that will be ready to take up the project results. Successful completion of the project will contribute to the recovery of abandoned poor soils, increase EU’s soil quality and water retention capacity, climate change mitigation, secure and independent energy supply, and sustainable bio-waste management.
Spatial Communication and Ageing across LAnguages (SCALA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Japan,Sweden,Finland,Norway,Italy,Denmark,United Kingdom
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2024-12-01
End date: 2028-11-30
Duration (months): 48.0
Total project cost (EUR): 3391742.06
EU funding (EUR): 3280082.4
Participants: 13
Project status: SIGNED

Spatial communication is fundamental to our species. Spatial terms, including spatial adpositions and demonstratives, are among the most frequent terms in languages and form the key connection between language and objects/locations in the world. Yet little is known regarding how spatial communication changes as one ages in later life and across different spatial scales and media. The focus of SCALA is to understand fundamentally how spatial communication changes in typical and atypical ageing across spatial scales, and how technology may be harnessed to afford enhanced understanding of spatial communication and support for spatial communication when needed in the context of an increasingly ageing European population. This DN will train the next generation of scientists in the full range of multidisciplinary and cross-sectorial methods necessary to make significant progress in understanding human-human and human-technology spatial communication across time and scales, with direct synergies between basic research and application. Training is structured around two interdisciplinary research themes - Spatial Communication in Typical and Atypical ageing, and Spatial Communication, Technology and Ageing - both involving systematic co-supervision and collaboration across sites, with extensive interplay between academic and non-academic beneficiaries and associated partners. In turn we expect that a range of applications will be enhanced with increased usability, and with associated societal and economic benefit. The training of the cohort of Doctoral Candidate Fellows follows innovative PhD training approaches and will provide comprehensive interdisciplinary training, embracing leading peer assisted learning methods that have been successively employed in previous DNs. This will produce a cohort of unique and highly skilled researchers ideally equipped to add significant value to both the public and private sectors.

Keywords: spatial communication ageing
Glycan foldamers: designing oligosaccharides to build three-dimensional architectures (GLYCOFOLD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 1499956.25
EU funding (EUR): 1499956.0
Participants: 1
Project status: SIGNED

Natural biopolymers have inspired the development of synthetic analogues – i.e. foldamers – capable of adopting defined conformations and forming programmable three-dimensional architectures. These compounds are mainly based on peptides and nucleic acids, that are well understood at the molecular level. The diversity, intrinsic chirality, and ability to generate hierarchical assemblies suggest that carbohydrates hold an even larger potential for the generation of three-dimensional structures. However, the complexity of carbohydrate synthesis and structural analysis have prevented access to synthetic carbohydrates capable of adopting defined geometries. I propose the creation of carbohydrate foldamers capable of 1) adopting rigid secondary structures and 2) assembling into supramolecular architectures. To achieve these goals, we will address fundamental questions related to carbohydrate structure, design new methods to stabilize particular conformations, and we will implement protocols for systematic structural analysis. State-of-the-art synthetic platforms (i.e. automated glycan assembly) and analytical techniques (i.e. NMR spectroscopy, microED, and single molecule imaging) will be the tools to complete this ambitious project. My group has proved to be very successful at gaining a basic understanding of carbohydrate structure and aggregation. Building upon these preliminary results, I aim to develop programmable carbohydrate architectures, which have the potential to open a new field of carbohydrate and supramolecular chemistry. Analogous to the birth of a new field after the discovery of peptide-based foldamers, carbohydrate foldamers could find applications in several areas, including material science, biology, and catalysis. Moreover, carbohydrate foldamers will expand our understanding of carbohydrate structures and interactions, and new analytical protocols will standardize the characterization of carbohydrate materials.

Keywords: foldamers,glycan conformation,synthetic glycans,supramolecular carbohydrate materials
Delineating the boundary between the computational power of quantum and classical devices (DebuQC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1807721.0
EU funding (EUR): 1807721.0
Participants: 1
Project status: SIGNED

This project sets out to assess, make use of and verify the computational power of realistic quantum devices. It comprehensively identifies quantum simulators and paradigmatic quantum devices that are computationally superior to classical supercomputers, based on presently available or plausible physical architectures. In doing so, it explores the fine line that discriminates regimes featuring a quantum advantage from ones that are accessible to efficient classical simulation. This naturally two-pronged approach is on the one hand concerned with (1) novel classical simulation tools for seemingly deeply quantum prescriptions and with identifying limitations of variational approaches and quantum simulation schemes. On the other hand, (2) it identifies new practically minded applications of quantum devices that exhibit a computational speed-up over classical machines, with potentially game-changing applications emerging for learning tasks. To achieve this goal, it digs deeply into computer science that provides sophisticated tools of computational complexity and of machine learning, and is instrumental in devising methods for the classical simulation of intricate quantum problems. At the same time, it draws on the physics of complex systems. This proposal suggests an interdisciplinary effort by bringing together ideas of quantum information, condensed matter physics, complexity theory, machine learning, tensor network theory, and methods that are unusual in this context such as signal processing. Individually, each objective substantially advances the respective field, but it is their combination that will permit a true breakthrough by delineating the delicate boundary between quantum and classical computations of synthetic quantum devices.

Keywords: near term quantum devices,quantum simulators,computational complexity,verification and benchmarking,classical simulation,quantum machine learning,tensor networks,sparse sampling,compressed sensing
Paleogenomic Analysis of Tuberculosis epidemiological Histories Over Geo-cultural and Ecological Networks in South America (PATHOGEN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-05-01
End date: 2025-04-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: CLOSED

Tuberculosis (TB), the infectious disease produced by the Mycobacterium tuberculosis complex (MTBC), remains one of the highest global disease burdens. However, the current body of knowledge on the MTBC is biased towards certain lineages, particularly lineage 4 that spread from Europe to the Americas during colonial expansion. Recent advances in ancient DNA research have the potential to broaden this picture with the recovery and analysis of whole genomes from strains that infected human populations in the past. Indeed, these approaches have been recently used to identify ancient MTBC animal associated strains infecting humans in South American before the arrival of Europeans. Analysis of these strains estimated that the MTBC most likely emerged during the Neolithic approximately 6000 years ago (much later than previously thought). The PATHOGEN project, will seek to use these approaches to shed new light on the emergence, diversity and spread of MTBC strains in the Southern Cone of the Americas, a neglected region concerning the epidemiological history of TB. By employing ancient DNA methods to examine and screen putatively positive TB infections of humans from archaeological and historic contexts of the current territory of Argentina, I will potentially provide genomic representation of TB histories over a broad time transect from precolonial populations to post-colonial cemeteries. With these data, I will perform phylogenomic and molecular clock analyses to investigate i) changes in strain diversity over time in the region, ii) the historical and socio-economical contexts that favoured the emergence and spread of the detected strains, iii) the emergence of genetic changes with potential clinical relevance identified in MTBC strains over the past centuries. By offering a view of the past, the PATHOGEN project will increase our understanding of the diversity of MTBC across time and contribute a new perspective of the evolutionary and epidemiological histories of TB.

Keywords: ancient dna,tuberculosis,south america,phylogenomics,pathogen genomics,pathogen evolution,emergence of infectious diseases,history of infectious diseases,mycobacterium tuberculosis complex
MIGRANTS IN THE POLITICS OF ENERGY DECARBONISATION (MIPED)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-08-15
End date: 2027-08-14
Duration (months): 24.0
Total project cost (EUR): 267418.56
EU funding (EUR): 267418.56
Participants: 1
Project status: SIGNED

Migrants In the Politics of Energy Decarbonisation (MIPED), a research project conducted by Rocío Hiraldo under the supervision of David Jordhus-Lier at the University of Oslo (UiO), will study the place of migrant workers in the politics of energy decarbonisation, a question underexplored in the literature yet highly relevant due to the growing recognition of the need of migrant labour in the attainment of European climate targets in the energy sector. Focusing on four case studies in Spain, MIPED will examine how the inclusion and exclusion of migrant workers’ labour concerns in mobilisations around energy decarbonisation is shaped by the socio-spatial interactions of migrant workers with labour, environmental and climate activists in this context. Through a combination of different fields of research, a qualitative and innovative methodology, a consideration of social inequalities intersecting this research question together with ethical and environmental issues, MIPED will address three research objectives: mapping how migrant workers’ experiences of (changes in) their labour conditions in the context of energy decarbonisation; studying how these experiences are taken into consideration by activist organisations mobilising around energy decarbonisation; exploring the social relations and socio-spatial interactions between these organisations and migrant workers. MIPED will reach academics, policy-makers, activists and society through the production of various research outputs including: 3 articles authored by the researcher, 1 to 3 articles co-authored by the researcher and academics at UiO, a policy brief, blog and newspaper articles, social media dissemination, an academic workshop, two project videos and a project blog page. The researcher’s background on MIPED topics and the two-way training process between the researcher and the host institution will ensure the successful attainment of project deliverables on due time.

Keywords: just transition low carbon development migrant workers political ecology environmental labour studies
Understanding and targeting cancer persister cells (CancerPersisters)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Israel
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-08-01
End date: 2029-09-30
Duration (months): 62.0
Total project cost (EUR): 1728750.0
EU funding (EUR): 1728750.0
Participants: 1
Project status: SIGNED

Despite tremendous progress in cancer therapy, many patients still succumb to the disease following an initial successful response to treatment. In addition to the long-appreciated contribution of genetically mutated cells to disease recurrence, persister cells, a rare subpopulation of cells that evade therapy in the absence of any known resistance-mediating mutation, have recently emerged as orthogonal drivers of therapy failure. While there has been much progress in targeting genetic resistance, the paucity of molecular tools that can capture persister traits, as well as the lack of a robust methodological framework for their study have significantly hampered our understanding and ability to target persister cells. Nevertheless, recent breakthroughs in molecular profiling techniques, as well as growing access to human residual disease clinical samples, now provide the opportunity to uncover the molecular underpinnings of this crucial cellular state. In this project, I propose to combine state-of-the-art single-cell lineage tracing techniques with functional approaches to (1) identify the determinants that control the ability of persister cells to escape therapy-induced senescence; (2) elucidate the cellular processes that govern the duration of persister drug-induced arrest; (3) investigate how epigenetic memory shapes persisters’ response to subsequent cycles of therapy. CancerPersisters will establish the tools that are needed in order to study key persister traits and further our understanding of this important cancer phenotype. Successful completion of this project may instruct the development of new classes of cancer drugs that can resensitize patients to subsequent cycles of therapy by erasing cellular memory and increase progression-free survival by modulating the duration of drug-induced arrest.

Keywords: persisters,non genetic mechanisms of drug resistance,treatment failure
Hybrid Human Artificial Collective Intelligence in Open-Ended Decision Making (HACID)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Innovation actions
Partnership: AI-DATA-ROBOTICS (co-programmed)
Countries involved: Italy,Germany,Ireland,United Kingdom
Call: AI, Data and Robotics at work (AI, Data and Robotics Partnership) (IA) (HORIZON-CL4-2021-DIGITAL-EMERGING-01, 2021)
Start date: 2022-09-01
End date: 2026-02-28
Duration (months): 42.0
Total project cost (EUR): 2164500.0
EU funding (EUR): 1877250.0
Participants: 5
Project status: SIGNED

HACID develops a novel hybrid collective intelligence for decision support to professionals facing complex open-ended problems, promoting engagement, fairness and trust. A decision support system (HACID-DSS) is proposed that is based on structured domain knowledge, semi-automatically assembled in a domain knowledge graph (DKG) from available data sources, such as scientific and gray literature. Given a specific case within the addressed domain, a pool of experts is consulted to (i) extract supporting evidence and enrich it, generating a case knowledge graph (CKG) as a subset of the DKG, and (ii) provide one or more solutions to the problem. Exploiting the CKG, the HACID-DSS gathers the expert advice in a collective solution that aggregates the individual opinions and expands them with machine-generated suggestions. In this way, HACID harnesses the wisdom of the crowd in open-ended problems, relying on a traceable process based on supporting evidence for better explainability. A set of evaluation methods is proposed to deal with domains where ground truth is not available, demonstrating the suitability of the proposed approach in a wide range of application domains. Demonstrations are provided in two compelling case studies contributing to the UN Sustainable Development Goals: crowd-sourcing medical diagnostics and climate services for urban adaptation.

Keywords: collective intelligence,decision support,medical diagnostics,climate services