Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
EEB ICT ClustERS (EEBERS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Technologies enabling energy-efficient systems and energy-efficient buildings with a low environmental impact
Action type: Coordination and support actions
Partnership: EeB (cPPP)
Countries involved: Germany,Spain,Finland,United Kingdom
Call: Support for the enhancement of the impact of EeB PPP projects (H2020-EeB-2014, 2014)
Start date: 2015-02-01
End date: 2017-01-31
Duration (months): 24.0
Total project cost (EUR): 498497.5
EU funding (EUR): 498497.5
Participants: 5
Project status: CLOSED

EEBERS focus on identifying opportunities for synergies in ICT related RTD in the EeB (energy efficient buildings) domain and to engage stakeholders in networking for future RTD and exploitation of results. There areabout 134 EeB direct and indirectly related projects that will be active beyond 2014. From these about 86 are likely to add¬ress ICT as one of their key priorities. – These projects are the primary target of this CSA. The tangible objectives of the EEBERS project are to: • Engage relevant stakeholders in identifying and exploiting opportunities for synergy. • Analyse and consolidate latest developments in the EeB domain. • Stimulate cooperation for future RTD and exploitation of results. The key factors to be considered by EEBERS when assessing RTD&I activities include: • Key stakeholders and links between them. • Project topics and links between them. • Project results and their TRL levels. • Links with innovation and technology transfer initiatives. The project will connect relevant innovation stakeholders with R&D results and with EU, national and regional levels initiatives within the construction, energy and ICT sectors. EEBERS will impact on speed up wide-scale deployment of solutions and services for building energy-efficiency. The consortium includes 3 academic and 1 industrial organisations from 4 countries in different EU climate zones. Together these are involved in a total of 39 EeB projects, from which 33 deal with ICT-related topics. The consortium will engage with relevant stakeholders in an early stage of the project, as well as with other similar ongoing CSA project.

Keywords: impact,clustering,technology transfer,buildings,dissemination,randd priotities
Density assemblages: intensity and the city in a global urban age (DenCity)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-09-01
End date: 2024-02-29
Duration (months): 66.0
Total project cost (EUR): 1344681.25
EU funding (EUR): 1344681.0
Participants: 1
Project status: SIGNED

DenCity offers a new approach for understanding density and its relationship to the city. Density is a defining feature of the city and urban life. Across the world, density is now at the centre of policy and planning agendas to build cities that are environmentally, economically, socially and politically ‘sustainable’. While there is a lively tradition of research on density in the city, we lack an understanding of the different ways in which high densities are lived and perceived by residents. Existing research provides rich resources for how we might define and represent density, how we might arrive at optimum numbers of people in a given area, and how capitalism builds or reduces densities within and between places globally. However, we lack an understanding of how high density – what I call intensity – is understood and experienced by different urban inhabitants, and the implications for how we understand the contemporary city. Developing a ‘density assemblage’ approach, I propose to examine the ways in which residents differently know and relate to intensity, including how it comes to matter, for good or ill. I do so by examining different cases of intensity in the Asian city, from travel and transport hubs, and slums to rooftops. While the 20th century witnessed a general global decrease of urban density in favour of urban sprawl, many Asian cities continue to densify. Asia is the densest and most urbanized part of the planet, and the trend is predicted to continue. I will examine some of the highest densities in the world, including in Hong Kong, Mumbai, Manila, Dhaka, and Tokyo. The different ways in which intensity becomes known and comes to matter for residents will be a vital challenge for understanding life in the urban 21st century, and for how we understand the city.

Keywords: assemblage,city,density
Chemically and Thermally Stable Nano-sized Discrete Organic Cage Compounds (CaTs n DOCs)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-04-01
End date: 2022-03-31
Duration (months): 60.0
Total project cost (EUR): 1996000.0
EU funding (EUR): 1996000.0
Participants: 1
Project status: CLOSED

Shape-persistent organic cage compounds consisting only of covalent bonds are fascinating synthetically targets, because they are studied as hosts for the selective recognition of guest molecules, such as artificial lectins, for catalysis in confined space or for the construction of a new type of porous material. For the latter, the shape-persistency and rigidity of the cage cavity is of utmost importance. There are in principle two existing strategies for the synthesis of shape-persistent organic cage compounds. Strategy I: A stepwise approach by irreversible reactions. Here, the advantage is the chemical stability of the target compound due to the intrinsic stabilities of the formed bonds. The disadvantage of this approach is in general the low overall yield, because the system does not allow any ‘self-correction’ of once formed bonds. This is different for the other approach used in Strategy II: By using dynamic covalent bond formation as synthetic tool, shape-persistent organic cages can be constructed from rather simple molecular building blocks in one step. Here, the yields are usually very high or even quantitatively, because the reversibility of the reaction allows the system to self-correct. Unfortunately, the resulting compounds are more prone to chemical cleavage of the cages than those synthesized by the irreversible approach. Within this project, we will combine the advantages of both strategies to synthesize chemically and thermally stable nano-sized discrete organic cage compounds in a two-step approach in high yields. To demonstrate the versatility and synthetic power of this approach, pure hydrocarbon cages will be synthesized in a few steps in high yields. Finally, this strategy will make for the first time open and closed-shell fullerenes and heterofullerenes that are isomerically pure, accessible.

Keywords: organic synthesis,aromatic materials
BLOCKCHAIN BASED PLATFORM FOR BRINGING SLOW FOOD IDEAS AND FAMILY OWNED FARMING TO CYBERSPACE (I Go Slow)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Estonia,Lithuania
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

During the last decades farming and production of gourmet foods, traditionally dominated by Mediterranean region, experienced a setback because of decrease of inhouse consumption. This forced the whole market towards export to strong economies with high quality of life. Export markets bring challenges to small farms and producers of gourmet foods. They have no experience and funds to cope with refocus from local sales to export. This puts them into disadvantage reaching international markets. The wish to get the share in export forces farms to accept wholesalers as a necessity, to sell at 30-50% of prices, to agree that distributors get the largest share of value created by farmers. I Go Slow offers a unique solution for the problems of the industry. The main objective is to develop a platform based on integration of Internet, e-commerce, Cloud and Blockchain technologies for promoting key ideas of Slow Food movement and family owned farming into cyberspace. For farmers the platform provides a user-friendly, reliable channel for presenting themselves directly to consumers without intermediaries. It requires little if any marketing funds, and allows engaging with customers directly for visits, product sales and sharing next harvest. All interactions are supported by underlying Blockchain technology and carried out with the use of a native Slow Token ecosystem. Any interaction between farmers and consumers strengthens Authenticity Rates, leaves no space for manipulations of intermediaries and builds trust. Trust gives credibility to farmers. It contributes to the secure content of global cyberspace. I Go Slow platform offers producers a compelling proposition to increase their global exposure, maximize profit by getting most of the created value themselves. It is a socially responsible proposition as I Go Slow will monetize the business using commission fees on transactions instead of subscription fees.

Keywords: blockchain,cloud,scalable secure database,secure content,trust building
The Diamond Revolution in Hyperpolarized MR Imaging – Novel Platform and Nanoparticle Targeted Probe (HYPERDIAMOND)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Germany,Israel,Germany,Austria,Germany,Switzerland,Switzerland,France,France
Call: Development of new diagnostic tools and technologies: in vivo medical imaging technologies (H2020-PHC-2015-two-stage, 2015)
Start date: 2016-01-01
End date: 2020-06-30
Duration (months): 54.0
Total project cost (EUR): 5073550.25
EU funding (EUR): 4866050.0
Participants: 14
Project status: CLOSED

Non-invasively imaging small numbers of molecular probes, to help image particular targets or pathways in vivo, is currently undergoing a technological revolution. Recent breakthroughs in molecular hyperpolarization proved > 10,000-fold increase in sensitivity on conventional magnetic resonance imaging (MRI) systems, thus providing insight into previously unseen metabolic processes with enormous potential for socioeconomic relevant diseases. E.g. pyruvate-based hyperpolarized imaging was clinically demonstrated to be effective for prostate cancer diagnostics in human patients. However, the current state-of-the-art hyperpolarization methods are expensive and cumbersome, limiting the access to hyperpolarization technology, and require long hyperpolarization times of 60-90 minutes per dosage; hyperpolarization probes exhibit short hyperpolarization duration (1-5 minutes), limiting the usage of hyperpolarization to metabolic imaging. A quantum technological breakthrough, Nitrogen-Vacancy defects (NV centres) in diamonds, is set to revolutionize the field of hyperpolarization for both hyperpolarizer and probes. The primary objective of HYPERDIAMOND is the development and commercialization of two new molecular imaging technologies for sensitive diagnosis and treatment monitoring, based on NV centres: The Diamond Hyperpolarizer will offer a cost- and time-effective solution for hyperpolarization that easily fits current MRI layouts, hyperpolarizes within 5 minutes, and improves clinical viability. The Nano-diamond (ND) Probe will introduce the first targeted MRI probe capable of achieving comparable molecular sensitivity to positron emission tomography (PET) with MRI systems, exhibiting extremely long hyperpolarization duration (~1 hour), and enabling non-metabolic hyperpolarized imaging. HYPERDIAMOND will bridge the gap between novel quantum and nanotechnology and their applications in hyperpolarized imaging, producing innovation not feasible with current technology.

Keywords: hyperpolarized imaging,quantum technologies
IPM-4-Citrus, Citrus desease Integrated Pest Management: from Research to Market (IPM-4-Citrus)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Germany,Tunisia,Türkiye,France,France,Lebanon
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2016, 2016)
Start date: 2017-04-01
End date: 2023-01-31
Duration (months): 70.0
Total project cost (EUR): 801000.0
EU funding (EUR): 801000.0
Participants: 11
Project status: CLOSED

IPM-4-Citrus aims to strengthen collaborations between academic and non-academic partners based in 3 European Member States (FR, GER, IT), 2 Associated Countries (Turkey and Tunisia) and 1 Third Country (Lebanon), in order to develop a new bio-pesticide active against citrus pests and scale it up from lab to market. The project’s research and innovation activities are based on a multidisciplinary approach, which aims at understanding and sensitising stakeholders about the health risk factors related to citrus pests and their treatment by chemical pesticides and developing an alternative Integrated Pest Management (IPM) approach based on biological control. Bacillus thuringiensis (Bt) based bio pesticides occupy almost 97% of the world’s bio pesticide market and their use was estimated to exceed 30,000 tons. Despite this widespread use, the originality of Citrus-IPM is to focus on 2 promising, newly identified strains (Bt kurstaki BLB1 and LIP), which were shown to be more efficient than the commercial (Bt kurstaki HD1). In conjunction with validation through field tests, the project will pave the way for future commercial exploitation of a new biopesticide product by drawing up a feasibility study for future spin-off activities and/or new production lines in partner SMEs. Staff secondments and inter-sector and international mobilities between complementary partners will represent a unique opportunity to optimise bioproduction processes and obtain high added-value bioproducts, while building up the partners’ skills and reinforcing the training of early-stage researchers through knowledge sharing and networking. Inter-sectors mobility will bring SMEs and researchers to work conjointly on conditioning procedures for field tests, impact evaluation and product maturation/exploitation. The project will also adopt a concrete RRI approach by favouring public engagement and informal education through the different outreach activities aimed at a variety of target groups.

Keywords: biopesticides,bascillus thuringiensis,d endotoxin,bioprocess intensification,scale up,formulation,biocontrol activity,delivery,field assay,economic maturation,spin off
Moving from Cure to Care: an integrated care delivery platform for a new person-oriented approach (Garsia)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Italy
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-08-01
End date: 2017-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Health and Social systems are complex by nature and frequently disorganized. Each country, region and even each hospital or town use different software solutions which do not communicate among them. The social and health professionals are not aware of some information within their own sector and totally blind to all information among sectors. This results in: confusion, repetition, delays, duplication, gaps in service delivery, and people getting lost in the system. All these shortcomings imply a high cost for the National Health and Social Systems as well as many inconvenience to the users. The Garsia® Socio-health platform allows the management of the life pathway for patient care through a personalized interdisciplinary approach that places the individual at the heart of the system, overcoming the traditional medical approach centred on curing a single pathology. Garsia meaningfully integrates relevant information from social services and health systems into a single integrated platform useful for each stakeholder involved in the patient#39;s treatment. It offers many advantages such as an interdisciplinary management of patients (chronic and multi-pathologic), service optimization and improvement, the empowerment of the patient, interoperability through international standards while reducing inappropriate costs (8 billion euro on NHS). SofTech is a 19 year old SME created by professionals in the social and clinical sector which generated €2.3 M turnover last year. Our major asset to succeed is that we have already penetrated the public market, as we have already contracts in place with relevant players on the Italian and French Social and Health Systems. We have estimated that after 5 years from launch, we will have engaged at least 150.000 patients, and will have hired 60 new employees (sales, technical, etc.) in different EU countries. We will earn almost €14.2M cumulative profit and generate a R.O.I of 7.83 by commercializing Garsia.

Keywords: intelligent medical management,person oriented data systems,integrative patient care,synchronized medical pathways,disruptive digital health,new market environment
Exploring the role of GPCR expression diversity in receptor physiology and drug response (GPCR Transcriptomics)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

G protein coupled receptors (GPCRs) are key regulators of cell homeostasis. Given their importance in cell physiology, they have been extensively exploited as drug targets. Despite this, many discordant observations on receptor signalling and on GPCR drug response remain unexplained. Changes in receptor expression in different human tissues can be a key contributor to such differences in GPCR behaviour. And still, no comprehensive study has characterized human GPCR transcriptomics and its impact on receptor function. Such an analysis could help answer fundamental questions on GPCR pharmacology such as: How are different receptor types distributed across human tissues and how does this affect receptor function? How does age and gender-related GPCR differential expression affect receptor pharmacology? And how does splice variant distribution in different tissues influence receptor signalling? In this project, I will address these questions by applying a computational biology approach combining publicly available transcriptomics data with information on receptor structure, intracellular coupling, and pharmacogenomics. This will allow obtaining for the first time a GPCR-wide distribution map across human tissues; determining how differential expression according to age and gender can affect GPCR function; and assessing the impact of alternative splicing on receptor integrity, regulation, and coupling. At the end of this project, these insights will be made publicly available to the research community through the development of a web resource associated with the widely-used GPCR database. Using such a multidisciplinary approach, the proposed analysis will help clarify the importance of different receptor transcriptional profiles in cell physiology and drug response, point to more relevant systems to study GPCR signalling and to characterise new drug candidates, and foster a more personalised medicine by considering expression variability in the general human population.

Keywords: gpcrs,structural biology,molecular pharmacology
Speeding up intra-system data transfer through optical data links and minimizing energy demand by a new generation of integrated circuits (IC2020)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Germany
Call: European SME innovation Associate - pilot (H2020-INNOSUP-2020-02, 2020)
Start date: 2020-11-27
End date: 2021-11-26
Duration (months): 12.0
Total project cost (EUR): 192857.14
EU funding (EUR): 135000.0
Participants: 1
Project status: CLOSED

The application of cutting-edge technologies like AR/VR or artificial intelligence in consumer products and industry demand for high-performance data transfer between processors, memory and peripherals. This is valid for e.g. self-driving cars but also for industrial data centres. However, the limiting factor nowadays (and for future scaling) is the data transfer within the system, specifically, by the factors: bandwidth, power, and space. In fact, so-called interconnects cause 30% of power consumption in data centres today (and data centres account for currently 2%, in the future estimated 8%, of electricity worldwide). At higher speeds, the electricity cost of currently used copper links already dominates over the hardware cost. Due to this and their unsustainable signal loss, copper links are increasingly replaced by optical solutions, e.g. vertical-cavity surface-emitting laser (VCSEL), which provide negligible frequency dependent loss, a high bandwidth and 10-times lower power consumption. The VIS team has repeatedly reached performance world records for their VCSEL products based on proprietary transmitter and receiver assemblies and own integrated circuits (ICs). Facing the challenge of continued scaling and data transmission capacity needs >200Gb/s, the industry needs a new generation of VCSEL chips. To develop those, some further optimized ICs are most important. Currently, IC development is outsourced by VIS with a significant supervising effort. Main objective of this proposal is to hire and integrate an IC design expert to finally extend IC performance in VIS VCSELs to enable 224Gb/s PAM4 single channel transmission at energy consumption of 1mW/Gbps (triple speed performance and -50% energy demand). The VIS business opportunity is to provide complete proprietary VCSEL solutions, triplicating the revenues and gaining a market share of >20 % of the datacom segment of this market within 5y. The innovation associate will gain a long-term career opportunity.

Keywords: data centre,vertical cavity surface emitting laser,copper link,ic design,network,optical component,modulation