Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Non-stationary respOnse of spaTially Extended Structures (NOTES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ireland,Netherlands
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-03-01
End date: 2013-02-28
Duration (months): 48.0
Total project cost (EUR): 403231.0
EU funding (EUR): 403231.0
Participants: 2
Project status: CLOSED

Failures of long span highway structures in Northridge earthquake (1994) and spatially extended transmission towers systems in Kobe earthquakes (1995) have clearly shown the significance of non-stationary effects of ground motions and its importance in earthquake geotechnical engineering. Similar detrimental vibration effects have been witnessed in vehicle induced ground transmission of vibrations from high speed railway tracks, both underground and at surface. There has been a rapid growth of infrastructure and transportation systems (like tunnels, pipelines etc.) in Europe over the last few decades, which are spatially extended structures. The non-stationary effects of vibrations are threatening to the safety of these systems making them vulnerable to vibrations transmitted through soil medium. The recent European design codes require these systems to be analysed for safety against spatially varying vibration effects, which will be mandatory in near future. The Structural Dynamics & Vibrations Group (SDVG) in Trinity College Dublin, Ireland has excellent research background on non-stationary vibration analysis with international reputation, and PLAXIS BV an SME in The Netherlands is a world leader in the field of finite element modelling in geotechnical engineering with emphasis on soil-structure interaction. The PLAXIS BV is a European technical IT company which has a range of user friendly technical software products for the infrastructure industry worldwide. This project provides a framework to bring the two partners (from academia and industry) together with complementary expertise, to transfer the knowledge for mutual benefit and development. It will contribute to the knowledge base development of a European SME with global market, innovating new products. It will also foster the FP7 targets of Sustainable Transport with safety and security under to man-made and naturally induced vibrations; applying the tools developed using Information Science & Technology.

Keywords: non-stationary effects,ground motions,vibrations,tunnels,pipelines,earthquake engineering,seismic analysis,earthquake geotechnical software
Development of a unique means of detecting and proving illegal administration of recombinant somatotropin in dairy cows (UNIQUE-CHECK)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,France,Belgium,United Kingdom
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-06-01
End date: 2013-05-31
Duration (months): 48.0
Total project cost (EUR): 1049294.0
EU funding (EUR): 1049294.0
Participants: 4
Project status: CLOSED

The ability to increase milk production in cow by bovine somatotropin (BST) was first demonstrated in 1930’s. The use of recombinant bovine somatotropin (rBST) in dairy cows has become a common practice in the Untied States (US) and many other countries as the commercial product became available in 1994. However the use and sale of rBST in the EU has never been approved and was banned in 1999 due to concerns on animal health and welfare, food safety and quality, and human health implication associated with the administration of rBST in dairy cows. Nevertheless, there are no direct methods available to date that are capable to detect rBST. The present proposal will, by the use of new technologies and a wide range of expertise, deliver a means of screening and confirming the presence of this unwanted growth promoter in milk. The collaboration within the project will bring together a university, a public institution and two private commercial diagnostic companies to produce novel solutions for monitoring the quality and safety of foods. The proposed research project will give an opportunity of Industry-Academia collaboration that will allow the transfer of high level scientific research into much needed commercial outputs. As a consequence, both academic and industrial partners as well as communities will all benefit, not only during the project but well beyond. The major research outcome will be the delivery of a rapid and simple screening test (dipstick and/or ELISA), a highly accurate and quantitative immuno-biosensor test, and a sensitive and specific chemical confirmatory test for rapid detection and unequivocal identification of the presence of rBST in milk. The formation of partnerships will strengthen the joint efforts to advance research in food safety and quality which benefits ultimately all partners involved, the consumers and the community as a whole.

Keywords: animal health & welfare,public health,food safety,dairy cows,recombinant bovine somatotropin (rbst),rapid detection,unequivocal identification,milk product
Comparative stem cell research in mouse and humans (INDUSTEM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Hungary,Germany,Netherlands
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-01-01
End date: 2012-12-31
Duration (months): 48.0
Total project cost (EUR): 902530.0
EU funding (EUR): 902530.0
Participants: 3
Project status: CLOSED

The InduStem project is aimed at creating a mutually beneficial training and transfer of knowledge program between a Hungarian SME and a Dutch and a German academic research institution. The scientific and industrial aim is to generate novel information on the generation and maintenance of induced pluripotent stem (iPS) cells in mouse and human and on their differentiation towards cardiac cells. Transposon mediated transgenesis technology will be studied for the first time to generate iPS cells.The iPS cells will be analysed and compared comprehensively with existing embryonic stem (ES) cell lines. The InduStem project links research activities in different mammalian systems, including murine and human, and in SME and academia. Training and transfer of knowledge activities are structured to assure the maximum efficiency in developing and exchanging the new standards between industry and academia and to expose the participating researchers to different environments and schools of thoughts. This is expected to be highly beneficial for their individual career development. The project is aimed to have an impact on the European Health sector. The main impact of the project is expected as integrating efforts in stem cell biology and cell therapy between industry and academia for long term collaboration. Furthermore, direct outcome of the project is expected from generating iPS cells potentially replacing ES cells in cardiac cell differentiation protocols in mouse and human, with potential applications in human regenerative medicine and tissue engineering fields and, beyond it, in pharmaceutical industry. The project paid special attention to avoid the use of live animals and human ES cells.

Keywords: natural sciences,induced pluripotent cells,embryonic stem cells,transposon generated transgenesis,cardiac cell differenciation,regenerative medicine
Efficient Location-Aware Audio-Visual Delivery of High-Quality Content to Mobile Devices (AVID-MODE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Greece,Greece,Italy,China
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-06-01
End date: 2013-05-31
Duration (months): 48.0
Total project cost (EUR): 1323240.0
EU funding (EUR): 1323240.0
Participants: 4
Project status: CLOSED

At the dawn of the new millennium, we have witnessed a proliferation of mobile devices whose functionality goes well beyond their initial use as telephones. Nowadays, apart from mobile phones, we have in our disposal geographic positioning devices, personal organisers, email and text communication assistants, music players which can store thousands of songs, and video players with medium-definition capabilities. It is becoming increasingly apparent that mobile devices should achieve a greater level of integration regarding the services they offer. The goal is that soon it will be possible to own a single inexpensive high-quality mobile gizmo, which can be used as a tele- and video- phone, email client, MP3 player, document and spreadsheet processor, GPS locator, and so forth. In addition, most mobile devices now include some sort of navigation capability, either through the integration of a standard GPS module, or through the clever use of the cellular network topology and signal strength. In this project, our focus is on the enhancement of high-quality video, sound, and television delivery capabilities of mobile devices that will enable them to provide interactive and immersive media applications. We will address limitations to current audio and video coding methods which restrict the use of mobile devices to offering only a low-quality streaming media presentation to the user. In order to overcome these limitations, novel algorithms which go well beyond the currently developed techniques and concepts are needed. An important aspect of this project is the conscious exploitation of the location awareness that these new devices offer, for dynamically adapting the delivery of multimedia content. The proposed consortium consists of partners with complementary expertise which covers all the involved research areas, from the point of capturing the media content to the point that it is dynamically presented through a location aware mobile device to the user.

Keywords: signal processing,electrical engineering,networked audiovisual systems,communication engineering
Vehicle Independent Electric Transmission Architectures (VIETA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Sweden,United Kingdom
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-09-01
End date: 2012-08-31
Duration (months): 36.0
Total project cost (EUR): 332592.0
EU funding (EUR): 332592.0
Participants: 3
Project status: CLOSED

Road transport is key driver of the European economy, and it underpins societal development and our way of life. It accounts for 11% of total European GDP and is a major contributor to EU employment and the competitiveness of many other industrial sectors This project, involving two SMEs and one University, concerns a rapid development of a European capability in electric drivetrains for low-carbon vehicles, with focus on urban electric vehicles and commercial vehicles, in order to meet the urgent needs of a rapidly growing market, in particular in London and other European cities. The proposed electric drivetrain is based on the novel concept of a Vehicle Independent Electric Transmission Architecture (VIETA) system, which has been provisionally filed for patent application by Cranfield University. The timely delivery, within the next two years, of a technology demonstration of the VIETA system will significantly enhance the EU’s capability to develop low carbon vehicles with urgency. It will also helps to achieve the long term goal of decarbonisation of road transport, as emissions avoided now are more valuable than those saved later. This is a people-centred program to mobilize the human capitals of the participating organization so that enhanced and new capability in road transport, and in particular electric drivetrain, is to be developed. For the 10 seconded researchers involved, the VIETA project provides significantly leveraged resources for effective acquisition of new skills, and refreshed career prospects. For the newly recruited researcher, the aim is to develop an accelerated and excellent career within a unique academic-industry partnership over two years. Budgeted at 380k euro, the project thus provides signficant benefits for the EU, with good prospect of high returns for investment, in terms of new and enhanced capability in a key automotive market. and the creation of new jobs and wealth for the EU citizens.

Keywords: propulsion systems engineering
Subversion of host trafficking machinery by Hepatitis C Virus to promote viral replication (HCV HOST TRAFFICKING)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2008-10-01
End date: 2012-09-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Hepatitis C virus (HCV) is an important cause of worldwide liver disease. Current therapies are inadequate for most patients. Improving the understanding of the life cycle of this virus may provide opportunities for new antiviral strategies. Like all characterized positive-strand RNA viruses, HCV is also believed to replicate its RNA in association with intracellular membranes, the details of its replication complex assembly are unknown. My long-term goal is to understand the molecular mechanisms used by HCV to form its membrane-associated replication complexes. I hypothesize that in order to assemble membrane-associated replication complexes, HCV hijacks and redirects the function of components of the host’s vesicular membrane trafficking pathways. I have recently discovered such an interaction between HCV non-structural protein 5A (NS5A) and TBC1D20, a Rab1 GTPase activating protein (GAP) implicated in ER-to-Golgi transport. TBC1D20 depletion impaired HCV replication, with no affect on cell viability. Preliminary experiments reveal that TBC1D20 might also be a GAP for Arf-1, a GTPase implicated in Golgi–to-ER trafficking, suggesting an exciting model wherein NS5A’s interaction with TBC1D20 can subvert both directions of ER-Golgi transport to promote the establishment of the HCV replication complex. This project aims to further determine the role of the NS5A-TBC1D20 interaction in the establishment of the HCV replication complex and to determine the role of Arf1 in HCV replication.

Keywords: non-structural protein 5a (ns5a),vesicular trafficking,golgi,rab1,arf1
Plasticity of Earth's mantle (POEM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2008-12-01
End date: 2012-11-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Plates tectonics theory is essentially justify by the physical and chemical properties of Earth’s minerals. Specifically olivine, the major mineral of the upper Earth’s mantle effectively controls the dynamics of the upper mantle and hence the interactions between the convective mantle and surface processes. Nevertheless, several processes are still poorly constrained. For instance, data on olivine plasticity at low temperature (T<1000oC) are crucially missing. The proposal is focused on the experimental determination of the plasticity of olivine under pressure and temperature conditions of uppermost Earth’s mantle. The objectives are to ascertain (1) the deformation mechanisms of olivine and olivine-rich rocks at conditions relevant of the mantle and (2) to quantify the plasticity as a function of the temperature and chemical environment (anhydrous or hydrous). An experimental and interdisciplinary approach has been designed. It associates high pressure and temperature deformation experiments on olivine single crystals in a Paterson vessel. The water content will be determined using FTIR. Mineral chemical compositions will be analyzed by EMPA. Finally, potential petrofabrics data will be acquired by EBSD. Geosciences Montpellier (France) has world-class analytical facilities and a strong multidisciplinary research group dedicated to the study of the Earth’s mantle and its dynamics. The applicant has a strong background in high pressure and temperature experimental methods and is well experienced in FTIR, techniques in which there are no researchers in Geosciences Montpellier. The collaboration with geodynamicists, and seismologists will broaden her research interests and open way to new projects. The “PoEM” project will thus allow a young European female researcher to stronger her professional career by establishing a sound research profile and promoting new collaboaration in France to those already established during her training years in Germany and the U.S.

Keywords: mineralogy,earthquakes,geomechanics
Integrated and functional Lab-on-Chip (INFULOC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Czechia,France,France,Germany,United Kingdom
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-03-01
End date: 2013-02-28
Duration (months): 48.0
Total project cost (EUR): 1269723.0
EU funding (EUR): 1269723.0
Participants: 6
Project status: CLOSED

The objective of this project is to create Lab-on-chip devices that allow sensitive analyte detection as well being highly integrated and have high functionality. The project will develop lab-on-chip platform technologies for fluidic manipulations and analyte detection and develop specific Lab-on-Chip (LOC) applications. Integrated and easy to use fluidic manipulations within LOC devices will be achieved through firstly use of electro-osmotic flow (EOF) and through on-chip pressure system and passive valves. We will also demonstrate that LOC devices can be designed to perform sophisticated fluidic operations over a large element array of microchambers. large scale valving integration approach will be used to achieve discrete fluidic operation for each microchamber element within the array. A convenient LOC macro-micro world interface for fluidic, mechanical and electrical elements will be developed as well as sensitive optical and electrochemical strategies for detection. Novel optical detection approach which involves increasing the pathlength of the radiation within the microfluidic channel will be further advanced for highly sensitive optical detection within LOC devices. Sensitive electrochemical transduction will also be developed. The developed LOC platform technologies will be incorporated as part of a disposable cartridge to be inserted within a handheld reader device for bioanalysis. Specifically, we will develop systems for (i) biochemical discharges of airborne enzymes, (ii) continuously monitored bioreactor array and (iii) natural toxic monitor for potatoes. The project will bring together a wide range of leading expertise from the public sector and research organisations to create LOC devices that are reproducible, have a small footprint, are easy to use and demonstrate commercial advantage. The project will lead to long term collaborations between the partners through e.g. the commercialisation of project outcomes.

Keywords: technological sciences,chemical engineering,polymer technology,biochemical technology,nanosystems,microsystems,food chemistry,analytical chemistry,multisensory technology,multi-sensing,sensors
Ultrasonic synthesis of oil-filled protein and polysaccharide microcapsules (SONOCAPS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-IRSES-2008, 2008)
Start date: 2009-01-01
End date: 2010-12-31
Duration (months): 24.0
Total project cost (EUR): 32400.0
EU funding (EUR): 32400.0
Participants: 1
Project status: CLOSED

The scientific objective of the research carried out in this International Research Staff Exchange Scheme is the design and synthesis of a novel class of biodegradable microcapsules using the mild chemistry of polysaccharides and proteins, using ultrasound-induced polymerization of macromonomers. Ultrasound induced polymerization of monomers in solution and in emulsions has been widely used in the past but so far has not been applied to polysaccharide macromonomers. In this proposal, we intend to apply this strategy to prepare oil-filled microcapsules by radical polymerisation at the oil/water interface of macromonomers. This approach can be considered as a general method for fabricating polysaccharide- and protein-based hollow microcapsules for application in both drug delivery and food science. Ultrasound will be also used as a technique for encapsulation. Microparticles will be loaded with anti-cancer agents, conventionally used for the clinical treatment of malignancies (e.g., doxorubicin) or innovative therapeutic agents as peptide nucleic acid (PNA).

Keywords: sonochemistry,surface chemistry,polymer chemistry,biomaterial engineering,pharmaceutical chemistry,food chemistry
Hybrid Nanocomposites and Their Applications (COMPOSITUM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Poland
Call:  (FP7-PEOPLE-IRSES-2008, 2008)
Start date: 2009-02-01
End date: 2013-01-31
Duration (months): 48.0
Total project cost (EUR): 451800.0
EU funding (EUR): 451800.0
Participants: 1
Project status: CLOSED

The main research objectives of the 4-year joint programme are: • to synthesise and characterise new hybrid composite and functionalised nanomaterials based on oxides, carbons, polymers and natural minerals; • to study their interaction with biological objects and environmental systems; • to elucidate the role of interfacial phenomena in these systems; • to study structure-properties relationship of nanocomposites in specific applications; • to evaluate performance of novel nanocomposites in biological media, environmental systems and specific industrial applications. Other objectives of the proposed collaboration are aimed at: • increasing individual mobility and career prospectives of each person involved; • facilitating transfer of knowledge between research groups involved via exchange visits; • providing training opportunities for early stage researchers; • disseminating results of the joint activities; The joint investigations will be carried out via transfer of knowledge and networking activities between four teams from Member States - Poland, UK, Hungary and Greece, and the National Academy of Sciences of Ukraine, an ICPC country with an economy in transition.

Keywords: surface chemistry,inorganic chemistry,nanotechnology,materials engineering,biomaterial engineering