Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Rethinking the Health Experience and Active Lifestyles of Chinese Students (REHEAL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-28
End date: 2021-01-27
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Rethinking the Health Experience and Active Lifestyles of Chinese Students Rising immigration rates into the European Union (EU) has brought increased cultural and linguistic diversity, but also increasing levels of inequalities and the associated challenges of their alleviation. The promotion of physical activity as part of a healthy lifestyle, particularly for the young, is an important part of the European policy to address health inequalities. Minority ethnic youth are amongst those groups with the lowest levels of physical activity, and are identified as a ‘risk’ group in ‘problem-orientated’, ‘deficit’ (and Western) approaches. Chinese youth is a specific group within this physically inactive category, and yet have rarely been the focus of research or policy initiatives. Although described by teachers as ‘model minorities’ - hardworking high achievers - in physical education, health and physical activity (PEHPA), little is known about Chinese youth’s physical activity involvement, or what might represent best practice in PEHPA promotion for this group. Using innovative, participatory methodologies, this research will map the influences on Chinese youth’s needs, meanings, and experiences in PEHPA, create strength-based, new knowledge that goes beyond existing ‘deficit’ approaches to inform strategies to promote their health and physical activity, and develop best practice guidelines for schools and communities. The training through research will be within the Diversity, Equity and Inclusion (DEI) research centre at Leeds Beckett University, one of the largest groupings of internationally renowned experts in the field, with supervision from the Centre head whose research programme provides an ideal match to the training requirements of the proposed research. The training will specifically extend the applicant’s theoretical expertise in contemporary theorising of ethnicity, race, intersectionality and inclusion/promotion; develop expertise in innovative research

Keywords: minority ethnic,active lifestyle,health,physical activity,chinese youth,race,gender,intersectionality,participatory methodologies,eurocentric,strengths based
SeafoodTrace: Intelligent Traceability Platform enabling full transparency in the Seafood supply chain (SeafoodTrace)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Iceland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-05-01
End date: 2018-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

More than 5 million tons of seafood are wasted annually in the EU. Traceability is key to reduce food waste and ensure that all food products in the EU are safe for consumers. This traceability and permanent monitoring of the supply chain gets even more crucial when products must be kept refrigerated as it is the case of seafood. Yet, singularities of the seafood supply chain, such as its global trade character and complex value chains make it difficult to consistently identify the origin and history of seafood products. Nowadays it is often still impossible to verify that the seafood we buy is safe to eat, reliably packed and shipped or properly handled. Digital innovations are going to be key in the global logistics market that is set to grow at a CAGR=7.5% in the period 2015-2024 surpassing the €15 trillion in revenues in 2023. Under this context Skynjar Technologies, an Icelandic SME with long-term experience in the seafood industry, is finishing the development of SeafoodTrace, an Intelligent Traceability Platform that will revolutionise the seafood industry by creating a one-stop shop covering traceability, quality control automation in inventory management and new format information for each box. With cutting-edge technology including anti-tamper smart labels based on printed, temperature sensors, each with a unique ID number, and an innovative, blockchain-enabled IoT platform, SeafoodTrace provides an end-to-end overview of the supply chain. Thanks to SeafoodTrace we will be able to reduce 20-40% the total seafood wasted along the supply chain. SeafoodTrace unique features - extensive transparency, education and product storytelling – will allow us to close the information gap from producer to consumer. SeafoodTrace will be ready for market uptake at the end of 2020. Thanks to our extensive network of contacts within the seafood sector, we expect to rapidly grow and surpass the €27 million revenues by 2023 and create up to 30 new positions in our company.

Keywords: seafood supply chain,intelligent traceability platform,transparency,quality control automation,food waste,iiot,sensor technology,temperature monitoring,unique identification smart card
Ultrasensitive detection of transmissible malaria (Malaria POC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: United Kingdom
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2019-10-01
End date: 2021-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Malaria affects millions around the globe. Affordable and accurate point-of-care diagnostic tests are needed for those in low- or middle-income countries as well as developed areas. Currently, only diagnostic tests for infection are available and are most commonly designed to detect histidine-rich protein 2 (HRP2), though HRP2-negative parasites evolved and escape detection by these tests. In addition to detecting and curing infection, another important strategy against malaria is battling transmission by inhibiting gametocytes to carry the disease from humans back to mosquitoes. However, there are no available point-of-care diagnostic tests capable of testing for malaria transmission competency. Within “Malaria POC” we aim to design a lateral flow-based test capable of detecting antigens corresponding to transmission competency, for use at the point-of-care. Our programme has expertise in designing point-of-care tests by incorporating platinum core-shell nanoparticles (PtNCs) called “nanozymes”, which facilitate an amplification step of the signal in the presence of antigen. Within this POC grant we aim to incorporate catalytic “nanozymes” in a lateral-flow diagnostic test that detects activation of mature gametocytes. Prof Molly Stevens (www.stevensgroup.org) will exploit technologies developed in the ERC Consolidator grant “NATURALE CG” (616417) and will be supported through collaborations with Prof Jake Baum, Professor of Cell Biology and Infectious Diseases at Imperial College London, an expert in malaria parasites.

Keywords: malaria,diagnostic test,engineering
Functional Electrical Contacts to Two-Dimensional Materials with Tunable Interfacial Oxides (ProTOC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-06-01
End date: 2020-11-30
Duration (months): 18.0
Total project cost (EUR): 131104.8
EU funding (EUR): 131104.8
Participants: 1
Project status: CLOSED

Two-dimensional (2D) van der Waals (vdW) materials are promising for future nanoelectronic devices. However, their performance is often hampered by the presence of a large number of defects at metal/2D material interfaces. The project ProTOC will extend the applications of atomic layer deposition (ALD) to engineer functional electrical contacts in 2D nanoelectronic devices using interfacial transition metal oxides (TMOs) of controlled stoichiometry and electronic properties. ALD-grown TMOs, vanadium and titanium oxides, are explored as interfacial layers that are vdW-bonded to 2D material MoS2 on one side and chemically bonded to the metal electrode one the other side. ALD allows for precise control of the oxide composition in order to tune electronic properties, such as work function, dielectric constant, and defect concentrations. The electronic properties of ultrathin ALD-oxides of different compositions and their complex interactions with 2D materials, which in turn affect transport, will be investigated in a combined effort using 2D field-effect transistor (FET) transport measurements, spectroscopic methods, and scanning probe microscopy techniques. The band alignment at the contacts can be adjusted by changing the composition of the ALD-grown layers, which may provide a new route to engineering desired contact behaviour over a broad range from rectifying or low resistance ohmic, depending on the end application. This contacting scheme will be exploited to achieve both p- and n-type conductance in MoS2 FETs, which is key for logic applications and difficult to achieve with 2D materials. This project will benefit from the complimentary knowledge and experience of researcher, who is an expert in device design, fabrication, and advanced scanning probe methods, as well as host, who provides unique capabilities and expertise in materials growth by ALD and the spectroscopic characterization of complex oxide films in the context of devices.

Keywords: atomic layer deposition,transition metal oxides,tmos,2d materials,van der waals materials,schottky barrier height,impedance spectroscopy,kelvin probe force microscopy
Empowering homecare solutions in advanced wound care (Piomic)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-11-01
End date: 2020-02-29
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Due to an aging population with growing rates of obesity and diabetes, over 50M patients suffer from hard-to-heal wounds annually, which has created a severe cost burden to global healthcare systems. Piomic Medical AG, a Swiss Med-Tech company founded in 2016, develops a medical device to promote wound healing processes in hard-to-heal wounds. The device matches market mega-trends for portability and patient self-management. The patient may benefit from a faster healing process, reduced pain and inflammation as well as an improved treatment outcome. Early traction allowed Piomic to conduct a first in human clinical trial to evaluate safety and efficacy of its product and engage CE certification under MDD regulation. The management team of Piomic consists of professionals with interdisciplinary knowledge in science and engineering, paired up with experts in regulatory affairs, life science and product development. We believe life shouldn't be defined by a medical condition. By developing a therapy which is safe and effective we hope to set a better future for everyone in need. The feasibility study aims to validate the commercial feasibility of Piomic with target market segments and key stakeholders. We will strengthen our financial planning and IP protection strategy necessary to improve our service and refine our go-to-market strategy. We will also specify product features needed for a fully commercialized solution upgraded to TRL 9, after the SME Instrument Phase 2. With a Total Addressable Market of €19.3 billion, we plan to reach €35m revenues by 2024 with 90+ FTEs employed.

Keywords: hard to heal wounds,diabetes ulcer,chronic wounds
Changing the electric-vehicle paradigm with green, long-lasting and fast recharge liquid batteries (Nessox)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-01-01
End date: 2019-06-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Electric vehicles are poised to replace the high-polluting gasoline transport, driven by international policies aimed to reduce greenhouse gas emissions. Nonetheless, market uptake of electric cars is still low, less than 1% of automotive sales in 2016. The adoption of electric vehicles is hindered by long recharging times (on average 4 hours) and limited autonomy (max 300 km), due to performances constraints of the Li-ion batteries, the state-of-art in e-vehicles. After 4 years of research, BETTERY has developed NESSOX, a patented new class of batteries that allow for fast recharge of the battery and outstanding performances in terms of autonomy, size and weight. The core technology is the patented design NESSOX, based on combining the lightness and high performances of the Li/O2 technology with the modularity of flow batteries, and a proprietary semi-solid catholyte based on a carbon nanoparticles, which assure flexibility and high performances. NESSOX intend to introduce a new paradigm in electric vehicle transportation, by finally freeing e-drivers from the inconvenience of long recharging stops and limited duration of the battery, thus unleashing the market adoption of e-vehicles. BETTERY plans to initially target the small vehicles market (e-bikes and e-scooters), and then move to the automotive sector. Global leaders in the automotive supply sector expressed their interest in collaborating for product development and distribution. BETTERY is a high-tech start-up founded in 2018 by engineers and chemists with extensive experience in research, product development and project management. The Phase 1 project will be a launch pad for the future commercialization of the system, enabling BETTERY to validate the Nessox performances and the market opportunity in key areas, assess the process’ economic performance indicators, and refine the business plan to attract the future investment needed for scaling up the production.

Keywords: battery,e vehicle,carbon footprint,greenhouse gasses,co2 impact
Multimodal integration and population dynamics in the Deep Cerebellar Nuclei (DeepPop)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-17
End date: 2024-01-16
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

The cerebellum is a key structure of the central nervous system that contains more than half the neurons of the brain. It is highly conserved across vertebrates and crucial for coordinated movement, motor learning and cognition. Cerebellar dysfunction causes a wide range of motor (ataxia, dystonia) or non-motor (autism, schizophrenia) disorders. It is made of two structures: the cerebellar cortex and the Deep Cerebellar Nuclei (DCN). While the former has been thoroughly studied, the DCN - the actual output of the structure - are much less understood. Technological limitations and experimental difficulties have limited the study of DCN processing rules both at the cellular and at the population level. A multidisciplinary approach combining recent discoveries on DCN structure, modern cell type labelling strategies and optogenetics, and novel optical tools based on work performed during my first postdoctoral project (acousto-optic 2-photon imaging coupled with GRIN lenses) will address the following fundamental open questions that limit our understanding of sensorimotor systems: 1) How are inputs carrying sensorimotor information from different parts of the brain (mossy fibres (MFs) and climbing fibres (CFs)) integrated by individual DCN neurons? 2) How are CFs and MFs carrying different sensory modalities processed by DCN neurons at the neuronal and dendritic levels? And how does it relate to distinct DCN neuron subpopulations? 3) What is the dynamic of these subpopulations during a behavioural task in vivo? The outcome of the DeepPop project will provide new knowledge of the computations performed in the cerebellum, novel optical solutions to study deep brain structures and data that will be used by the wider community (e.g. modellers, theoretician, clinicians) and increase our general understanding of sensorimotor systems.

Keywords: 2 photon imaging,acousto optic imaging,optogenetics,cerebellum,deep cerebellar nuclei,sensortimotor processing,calcium imaging,in vivo imaging,electrophysiology,neuroanatomy,rt 3dmc
Remote Assessment of Disease and Relapse – Alzheimer’s Disease (RADAR-AD)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Public-private partnerships
Destination: Innovative Medicines Initiative 2
Action type: Research and Innovation actions
Partnership: IMI2 (Art-187)
Countries involved: Germany,Germany,Sweden,Switzerland,Switzerland,Belgium,Greece,Switzerland,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom,Luxembourg
Call: Development and validation of technology enabled, quantitative and sensitive measures of functional decline in people with early stage Alzheimer’s Disease (RADAR-AD) (H2020-JTI-IMI2-2017-12-two-stage, 2017)
Start date: 2019-01-01
End date: 2023-06-30
Duration (months): 54.0
Total project cost (EUR): 7659120.0
EU funding (EUR): 4999757.0
Participants: 17
Project status: SIGNED

There is an urgent need for novel approaches assessing functional decline in early AD. The main goal of the RADAR-AD project is to develop a digital platform to detect subtle functional deficits in early Alzheimer’s disease (AD) individuals by integrating a meaningful combination of smartphone, wearable and/or home sensor based parameters. The system developed will be suitable for future longitudinal studies, including trials. The objectives are to 1) Identify the most relevant functional domains and the most promising remote measurement tools (RMTs) for these domains based on reviewing the literature and piloting of RMTs in small studies; 2) Optimise the RADAR-CNS platform for use in AD studies; 3) Test the platform and selected RMTs in a real world environment clinical study with 240 participants across the AD spectrum ranging from the preclinical AD to the dementia stage; 4) Perform statistical modelling to estimate longitudinal predictions; 5) Discuss results with regulatory agencies in order to obtain guidance about how to develop a path for formal qualification as outcome measurements in future therapeutic interventions. Considering the limited budget and project duration, we will rely upon already available technology platforms and on available longitudinal datasets where possible. The consortium includes experts in clinical dementia studies, computer science, bioinformatics, regulatory policies, ethics, and patient and public involvement (PPI). Additional strengths of the consortium are the deep and broad interface with RADAR-CNS and related IMI projects, and the access to large amount of patient-level data from key European cohort studies for modelling purposes.

Keywords: functional impairment,patient and public involvement ppi,digital platform
GRoup thinking: new fOUNDationS (GROUNDS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-03-01
End date: 2024-08-31
Duration (months): 66.0
Total project cost (EUR): 1997959.0
EU funding (EUR): 1997959.0
Participants: 1
Project status: SIGNED

This project builds new foundations for collective attitudes and representational states: group belief and group desire. The platform is the PI’s recent advances in the metaphysics of representation for individual representational states, where he develops and defends a substantive, realist interpretationism: (i) what it is to believe/desire that p is for the selected interpretation to attribute that belief/desire to them; (ii) the selected interpretation is that which makes the subject most reason-responsive, given the way they act and the evidence available to them. This project leverages this work to construct a common structure for the metaphysics of group representation and individual representation, isolating parameters that differentiate the cases and theorizing the distinctive ingredients of the group case. The first phase of the work places group representation in context, studying the theoretical deployments of group attitudes, and dependencies between accounts of individual representation, group representation and linguistic representation. The second phase lays the basis on which interpretations of individuals and groups are selected---individual and joint action, and individual and joint evidence. An account of such facts must be given prior to and independent of belief and desire, on pain of circularity in the overall account. The third phase examines the relation between foundations of representation and metaphysics of persistence---required if the basis for interpretation is to be modally and temporally extended. The fourth shows how key issues in the theory of normative reasons will impact the metaphysics of content, given appeal to reasons responsiveness at the heart of the account. The fifth phase identifies the boundaries between realist and anti-realist accounts of group thought.

Keywords: metaphysics of representation,radical interpretation,metasemantics,joint action,group belief,personal identity,metaphysics of groups