Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The Coro: a revolutionary product to bring breastfeeding into the 21st century (TheCoroRevolution)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Ireland
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-12-01
End date: 2023-08-31
Duration (months): 45.0
Total project cost (EUR): 2158862.0
EU funding (EUR): 1506828.0
Participants: 1
Project status: SIGNED

Never before has so much been known about the multitude of health benefits of breastfeeding, yet we are in the midst of a global breastfeeding crisis. The single most commonly identified reason globally is maternal concern regarding insufficient breast milk supply. Even when support and education are optimised to minimise unnecessary anxiety, the rates of breastfeeding continue to be abysmal. All commercial and research methods developed to date to address the issue have failed. The Coro is a novel microsensor embedded within the standard nipple shield, providing accurate, real-time milk volume data directly to the mother via an app. Our data will also generate volume rates across countries, in specific maternal and baby age populations, will correlate volume to baby weight and allow multiple-variable, deep data mining. Through collaborations with research groups and health agencies, the data generated will finally fill the fundamental gap in breastfeeding knowledge and assist future efforts to increase breastfeeding rates on a global level. The commercial opportunity is vast with virtually no competitors and perfectly aligned with global trends in wearable health technology. We have a strong founding team who have leveraged their personal predicament and professional backgrounds to invent a game-changing product. We have protected our valuable IP, built a partnership with a leading university research group to clinically trial the Coro, signed our first distributors and won several awards. Our vision is to become the primary source for breastfeeding volume measurement products, information, and analysis. The SMEI would ensure we bridge the gap to market by funding the product’s industrialisation, pre-commercialisation and clinical validation to build crucial scientific credibility. This would allow our company to harness societal and policy trends and scientific and technological advances to finally pivot the global tipping point in favour of breastfeeding.
RO-Boost Inno SMEs – Boosting the Innovative Potential of Romanian SMEs (RO-BOOST INNO SMES 3)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Romania,Romania,Romania
Call: EEN H2020 SGA3 (H2020-EEN-SGA3-2018, 2018)
Start date: 2019-01-01
End date: 2019-12-31
Duration (months): 12.0
Total project cost (EUR): 45010.0
EU funding (EUR): 45010.0
Participants: 5
Project status: CLOSED

In the context of innovation-divided Europe and scarce consultancy in RDI, Macro Region 4 Romania is in full process of moving towards a "turning point" of economic positioning in a climate of globalization, disruptive innovations and circular economies. This dynamic brings to surface impediments innovation actors in the region face multiple challenges, while their ability to overcome them is crucial to the impact of such changes. The core members of the Ro-Boost SMEs consortium are aware that it is time for smart action in order to achieve the goal of reducing the innovation divide among companies. Based on the vision stated in the Ro-Boost SMEs Implementation Strategy, the core members of the consortium jointly elaborated the project "Ro-Boost Inno SMEs" aimed at consolidating innovative businesses - rooted into the Smart Specialisation Strategy - and to expand their position within the sector global value chains. To achieve this goal, dedicated innovation support envisaged at the beginning of 2015 shall be continued in order to increase added value of SMEs and innovative sectors in the global economy, using an innovative delivery system and consolidating the community of innovators. The proposal is built around the expertise of relevant partners at Macro Region 4 level and in-depth competences gained in 2015-2016. It shall also capitalize on the impact generated in the previous period in order to gain further recognition of the innovation management as success driver among SMEs in terms of both economic impact and innovation culture within business environment.

Keywords: inovation management,sme instrument coaching,een services
Stimulation of Multiple Organoids Simultaneously (STIMOS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-02
End date: 2021-09-01
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: CLOSED

This project aims to develop STIMOS, an in-vitro platform to simultaneously stimulate and record from multiple mouse or human derived 3D retinal organoids by high-density multi electrode arrays.

Keywords: retina electrophysiology,multielectrode arrays technology,visual restoration,retinal ganglion cells,axons,mouse induced pluripotent stem cell derived organoids
Racialization in Reproduction: maternal health crisis among black women in Europe and the US. (RiR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France,United States
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2023-12-21
Duration (months): 36.0
Total project cost (EUR): 257619.84
EU funding (EUR): 257619.84
Participants: 2
Project status: SIGNED

tThe Racialization in Reproduction project (RiR) aims to analyse maternal health among black women in Europe and the US. Since the 2000s, a number of parallel trends testify that the maternal health outcomes of non-white populations (i.e. Black, Hispanic, Caribbean, Asian, Middle East and Pacific Islander women) are worse than those of white women in Europe and the US. Among non-white populations, black women present the worst maternal health outcomes in both contexts. This has led some scholars to speak about a black maternal health crisis, drawing on facts such as black women undergoing a greater number of medical interventions and being more exposed to risks related to maternal health. However, black maternal health matters are poorly understood as a public health problem in Europe where there is little data collected by race and ethnicity. RiR will introduce new theories and new methods to advance the knowledge of black maternal health in Europe. The project will consist of two key activities: theoretical training in the US where I will explore Black Studies literature that is missing in Europe; and research work to be carried out in the US to reflect in a comparative way on black maternal health in Europe. The overarching aim is to explore the continuities and specificities of the black maternal health crisis in Europe (where I have worked and collected data on this topic for the last ten years) and in the US (where I will carry out new fieldwork). In addition to dissemination in the academe, RiR aims to spread its results to a broad public: medical professionals, reproductive rights associations and NGOs, public health and gender policy-makers. Through these activities, RiR will make a concrete contribution to public health policies aimed at struggling inequalities related to the right to health in Europe.

Keywords: black maternal health,african migrants,women of african descent,gender,race and class discrimination and inequalities,public health policies,right to health,comparative studies,ethnography
Establishing in-depth services enhancing the innovation management capacity of South West of France SMEs in 2019 (MAGIC SWF SMES 2019)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: France,France
Call: EEN H2020 SGA3 (H2020-EEN-SGA3-2018, 2018)
Start date: 2019-01-01
End date: 2019-12-31
Duration (months): 12.0
Total project cost (EUR): 158403.75
EU funding (EUR): 158402.0
Participants: 4
Project status: CLOSED

The project involves 3 partners of the Enterprise Europe Network South West France consortium which covers the region Nouvelle-Aquitaine and the Midi-Pyrénées territory. The general objective is to contribute to raise the competitiveness of SMEs from this area by offering support services in the area of innovation management. The project will also contribute to develop more efficient and more effective innovation processes and higher quality innovation management capacity assessment and support services. The support will be delivered as service packages to 2 groups of SMEs: a) Beneficiaries of the Horizon 2020 SME Instrument, Fast Track to Innovation and Future Emerging Technologies Open: to enhance the probability of a successful exploitation of the innovation project results and lead to the sustainable growth of the beneficiary beyond the participation in Horizon 2020. The support service will pinpoint weaknesses in the innovation capacities of the beneficiary, select suitable coaches to address the identified weaknesses and monitor the coach-client relationship and to accompany the beneficiary through the SME instrument project b) SMEs with significant innovation activities and a high potential for internationalisation: to enhance their innovation management capacities to be able to gain new international markets and leaderships. The support service will consist in an in-depth innovation assessment in order to develop and implement a tailored action plan to improve the SMEs capacity to manage innovation processes. The partners will use dedicated assessment tools: IMP3rove, Check’Innov and Innovation Way. The project will last 12 months and will provide 63 support service packages.

Keywords: innovation management,sme instrument,sme support,funding,europe,fast track to innovation,future emerging technologies
European Integrated Research Training Network on Advanced Cryptographic Technologies for the Internet of Things and the Cloud (ECRYPT-NET)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Switzerland,Belgium,France,France,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-03-01
End date: 2019-02-28
Duration (months): 48.0
Total project cost (EUR): 3893199.84
EU funding (EUR): 3893199.84
Participants: 15
Project status: CLOSED

The goal of this ETN is to develop advanced cryptographic techniques for the Internet of Things and the Cloud and to create implementations that offer a high level of security and increased usability, for a wide range of physical computation platforms. The ITN will equip a group of 15 early stage researchers with a set of interdisciplinary skills combining mathematics, computer science and electrical engineering that will allow them to create advanced cryptographic solutions that will be available for commercial applications. The 8 partners (including 2 companies) are leading research teams in the area of applied cryptology with a strong track record of collaboration; it is complemented by 6 partner organisations from industry (including 2 SMEs).The training from the ERSs will be guided by a personal development plan. A central component is training by research supported by an intensive program of workshops, summer schools, seminars, research visits, and secondments. The training will be complemented with transferable skills that also support the transfer of research to an industrial context. The management structure of the project is built on a pro-active approach with responsibilization of the fellows. The dissemination and outreach of the project activities target a broad range of stakeholders. The ITN contributes to the ERA by helping to overcome the fragmentation in the area of applied cryptology. The research supports the trust and security component of the Digital Agenda for Europe and responds to the growing attention of EU policy makers for societal needs related to privacy and cybersecurity. The societal relevance and timeliness of this research has been emphasized by revelations made by Snowden, that provide clear evidence of mass surveillance by nation states and of serious weaknesses of our current infrastructure. An essential component of a response to these revelations consists a broad deployment of advanced and innovative cryptographic techniques.

Keywords: cryptology,internet of things,cloud,information security,privacy,symmetric cryptography,public key cryptography,side channel attacks,fault attacks
A new instrument for mapping the ultrafast photo-conductivity of materials for optoelectronics (MicroMap)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-09-01
End date: 2017-02-28
Duration (months): 18.0
Total project cost (EUR): 148750.0
EU funding (EUR): 148750.0
Participants: 1
Project status: CLOSED

The introduction of new photo-active materials with enhanced performance is enabling a fast technological development in fields such as photovoltaics, photodetection, display technology and imaging systems. The efforts on the improvement of the synthesis and growth of these materials are in many cases not accompanied with equal efforts on the development of appropriate techniques that enable their characterization. MicroMap aims to develop a commercial instrument for the contact-free characterization of the high frequency photoconductivity of materials. The demonstrator will consist of an optically pumped near-field microscope and far-field spectrometer to map the response of photo-excited materials over areas of varying size from micrometers to several centimeters. This unique combination of length scales will enable to probe the conductivities of full devices and to determine the conductivities and carrier life times in single or few nanostructures or small areas to define the microscopic origin of the factors limiting the photoresponse. To demonstrate the feasibility of the instrument for the characterization of materials, we plan to test it on novel materials being currently investigated for optoelectronic applications. These include graphene, nanowires and perovskites. These tests will be used to elaborate technical notes that will help the commercialization of the instrument. The outcome of this project will be licensed to Protemics GmbH, which is a privately held spin-off of the research company AMO GmbH and the Institute of Semiconductor Electronics (RWTH Aachen University) with a background of two decades in THz technology . The target market for the instrument is academic and industrial research organizations working on materials research. We will also carry out a detailed business analysis to identify broader possibilities, e.g., for material characterization in industrial production or for THz sensing.

Keywords: thz spectroscopy,thz near field microscopy,photoconductivity,graphene,semiconductor nanowires,perovskites
Pathogen-phage cooperation during mammalian infection (CoPathoPhage)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Israel
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-10-01
End date: 2024-09-30
Duration (months): 60.0
Total project cost (EUR): 2200000.0
EU funding (EUR): 2200000.0
Participants: 1
Project status: SIGNED

Most bacterial pathogens are lysogens, namely carry DNA of active phages within their genome, referred to as prophages. While these prophages have the potential to turn under stress into infective viruses which kill their host bacterium in a matter of minutes, it is unclear how pathogens manage to survive this internal threat under the stresses imposed by their invasion into mammalian cells. In the proposed project, we will study the hypothesis that a complex bacteria-phage cooperative adaptation supports virulence during mammalian infection while preventing inadvertent killing by phages. Several years ago, we uncovered a novel pathogen-phage interaction, in which an infective prophage promotes the virulence of its host, the bacterial pathogen Listeria monocytogenes (Lm), via adaptive behaviour. More recently, we discovered that the prophage, though fully infective, is non-autonomous- completely dependent on regulatory factors derived from inactive prophage remnants that reside in the Lm chromosome. These findings lead us to propose that the intimate cross-regulatory interactions between all phage elements within the genome (infective and remnant), are crucial in promoting bacteria-phage patho-adaptive behaviours in the mammalian niche and thereby bacterial virulence. In the proposed project, we will investigate specific cross-regulatory and cooperative mechanisms of all the phage elements, study the domestication of phage remnant-derived regulatory factors, and examine the hypothesis that they collectively form an auxiliary phage-control system that tempers infective phages. Finally, we will examine the premise that the mammalian niche drives the evolution of temperate phages into patho-adaptive phages, and that phages that lack this adaptation may kill host pathogens during infection. This work is expected to provide novel insights into bacteria-phage coexistence in mammalian environments and to facilitate the development of innovative phage therapy strategies.

Keywords: intracellular bacterial pathogen,bacteriophage,prophage,listeria monocytogenes
Sensorimotor plasticity in the cerebellar microcircuit and its therapeutic potential (CerebellumTherapy)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-03-01
End date: 2019-02-28
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Neural circuits operate to drive behaviour and can cause debilitating brain disorders when malfunctioning. However, how circuit activity is causing learning and action and which modifications underlie the development of a disease is mostly unknown. The cerebellum is an ideal structure to tackle this issue because of its well-characterised anatomy, established motor learning and control theories, and relevance to pervasive brain disorders like autism. However, our cellular and circuit-level understanding of the cerebellar roles in learning and modulating behaviour and in modifying disease is still not satisfactory, therefore the therapeutic potential of cerebellar intervention is underestimated. In this proposal, I will address this potential by combining multi-colour two-photon imaging and optogenetic interrogation in the cerebellar cortex of wild type and disease model mice performing a multi-sensory association task. My first goal is to characterise the circuit operation of the cerebellum at unprecedented resolution. I will record two identified neuronal inputs simultaneously using independent expression of green and red fluorescent probes in neurons in the cerebellar cortex to investigate how multi-modal sensory inputs are associated during motor adaptation. The second goal is to define detailed cerebellar circuit deficits by using above methods in autism model mice. Finally, I will establish the causal roles of these neuronal inputs for this adaptive behaviour. I will perturb these motor control- and learning-related neuronal inputs and outputs using optogenetics to probe their unique contribution. I will apply similar optogenetic manipulations to restore the function of the dysregulated cerebellar circuit in autism model mice. Ultimately, I will build a bridge between this experimental technique and a human-applicable method. Together, this project will provide substantial insights into the implementation and refinement of clinical cerebellar manipulation.

Keywords: purkinje cell,parallel fibre,climbing fibre,dual colour two photon imaging,all optical optogenetics,transcranial direct current stimulation
Signals to Solutions: a change of paradigm in predictive maintenance market (S2S)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Norway
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-06-01
End date: 2018-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Rotating machinery downtime and breaking cause huge economic losses to industry. Due to this, Predictive Maintenance (PM) is gaining popularity among those manufacturers willing to extend their assets’ lifecycle, decrease maintenance costs and minimize unplanned production breaks. However, State-of-the-Art PM techniques are still based on old assumptions (i.e. signals stationarity) which do not fit anymore with the emerging flexible and variable production models. Signals to Solutions (S2S) is the only available PM tool capable of analysing at a fast speed non-stationary data, which better reflect real production cases, where the intensity of use of machines varies according to different time schedules, productivity needs and working conditions. S2S will be able to extend industrial equipment lifecycle by up to 4 times comparing with standard maintenance approaches, reduce by up to 130% the overall costs for equipment operation & maintenance, eliminate unplanned machinery downtime and erase the risk of environmental and human-related disasters linked to machinery failure. There is no competitor capable of reproducing our solution. PM is a fast-growing international market and is expected to reach € 8.84bn by 2022. Current PM market is dominated by few international companies and a direct competition with them would be hard. Therefore, in order to quickly access the market and avoid its entry barriers, we will establish strategic partnerships with: a) equipment manufacturers, to embed S2S directly in their equipment; b) current PM vendors, to integrate S2S in their PM solutions. Through our Feasibility Study we will pinpoint our strategic partners and identify the best technological fine-tuning for S2S. We aim to introduce S2S to key industries for the EU such as Aviation and Offshore drilling, representing a potential €64bn market. Our goal is to reach €23.8m annual turnover by 2025 (0,027% market share), with €22.7m accumulated profits and 99 new jobs created.

Keywords: predictive maintenance,rotating machinery,hilbert huang transform,equipment lifecycle extension,downtime avoidance,repair and maintenance costs optimization,civil aviation,offshore drilling