Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Four-Dimensional Monitoring of Tumour Growth by Surface Enhanced Raman Scattering (4DBIOSERS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Spain
Call: ERC Advanced Grant (ERC-2017-ADG, 2017)
Start date: 2018-10-01
End date: 2024-09-30
Duration (months): 72.0
Total project cost (EUR): 2410771.0
EU funding (EUR): 2410771.0
Participants: 1
Project status: SIGNED

Optical bioimaging is limited by visible light penetration depth and stability of fluorescent dyes over extended periods of time. Surface enhanced Raman scattering (SERS) offers the possibility to overcome these drawbacks, through SERS-encoded nanoparticle tags, which can be excited with near-IR light (within the biological transparency window), providing high intensity, stable, multiplexed signals. SERS can also be used to monitor relevant bioanalytes within cells and tissues, during the development of diseases, such as tumours. In 4DBIOSERS we shall combine both capabilities of SERS, to go well beyond the current state of the art, by building three-dimensional scaffolds that support tissue (tumour) growth within a controlled environment, so that not only the fate of each (SERS-labelled) cell within the tumour can be monitored in real time (thus adding a fourth dimension to SERS bioimaging), but also recording the release of tumour metabolites and other indicators of cellular activity. Although 4DBIOSERS can be applied to a variety of diseases, we shall focus on cancer, melanoma and breast cancer in particular, as these are readily accessible by optical methods. We aim at acquiring a better understanding of tumour growth and dynamics, while avoiding animal experimentation. 3D printing will be used to generate hybrid scaffolds where tumour and healthy cells will be co-incubated to simulate a more realistic environment, thus going well beyond the potential of 2D cell cultures. Each cell type will be encoded with ultra-bright SERS tags, so that real-time monitoring can be achieved by confocal SERS microscopy. Tumour development will be correlated with simultaneous detection of various cancer biomarkers, during standard conditions and upon addition of selected drugs. The scope of 4DBIOSERS is multidisciplinary, as it involves the design of high-end nanocomposites, development of 3D cell culture models and optimization of emerging SERS tomography methods.

Keywords: nanoplasmonics,surface enhanced raman scattering,biosensing,cell spheroids,3d cell models,nanomedicine
Neural mechanisms of perceptual Stability in magnitude perception (NeSt)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-06-01
End date: 2021-05-31
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: CLOSED

Magnitude dimensions such as space, time, and numerosity represent fundamental aspects of the external world. A correct perception of these dimensions is needed to understand the spatial properties of the environment and navigate through it, its temporal structure, cause-effect relations, and duration of events, and the number of objects that are present in the visual scene. As magnitude dimensions share similar properties and are often intertwined in the perceptual environment, they are thought to share a similar neural mechanism called the generalized magnitude system. However, while object and events in the space surrounding us usually appear as stable, embedded in a seamless stream of perception, neuronal activity is usually very noisy, and biological sensors like the eye are unstable due to continuous movements. Visual magnitude representation is thus subject to the noisiness of neuronal processing. How does the brain achieve such a remarkable stability despite the noisy nature of its complex machinery? The goal of this proposal is to investigate the brain processes ensuring the stability and continuity of visual magnitude information, using psychophysical, electroencephalography (EEG), and brain stimulation techniques (TMS). Recent studies suggest that to achieve perceptual stability and continuity the brain integrates visual information over time, giving rise to perceptual biases known as serial dependence. While serial dependence has been linked to stability and investigated across several domains, little is known about how magnitude information is stabilized and whether a generalized stability mechanism exists. By taking an interdisciplinary approach, NeSt thus aims to address these issues from a novel perspective and shed new light on the mechanisms ensuring continuity and stability of spatial, temporal, and numerical information.

Keywords: visual stability,visual perception,magnitude perception,perceptual continuity,serial dependence,numerosity perception,time perception,object size perception
Baltic Paganism, Osteology, and New Examinations of Zooarchaeological Evidence (BONEZ)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-01-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

Baltic Sea communities faced intense pressures from the 12th to 13th century AD, including colonization, forced conversions, and environmental change. The social resiliency of these communities in response to this crucial inflection point remains controversial. Did the external pressures catalyse the formation of a regional pan-Baltic identity? Or did splintered, hyper-local responses intensify differences between communities? The clearest measure of these seismic social shifts is how religious and mortuary behaviour changed in response, as communities create and negotiate a shared identity through the performance of ritual. The BONEZ project integrates multi-proxy osteological methods to investigate funerary and non-funerary ritual deposition of animals at five cemetery sites in Poland, Lithuania, and Kaliningrad before, during, and after colonization (1st to 13th AD). By combining long-established osteological methods with cutting-edge, high-resolution histological, isotope, and proteomic analyses, BONEZ reconstructs where, how, why, and with whom animals were treated and deposited in pre-Christian cemeteries. BONEZ will be the first study to unite the study of Baltic ritual activity with broader academic discussions of pre-Christian religion through rigorous scientific analysis of underutilized bone assemblages. This research has the potential to transform our perception of shifting tribal affinities using changes in ritual practice as an index of social resiliency. The first-of-its-kind integration of these methodologies as well as the regional and temporal scale of the analysis make BONEZ highly innovative and a key case study in the comparative osteology of complex skeletal assemblages. This research will have significant legacy benefits for the broader anthropological community as a state-of-the-art methodological blueprint for multi-proxy research on complex ritual deposits as an index of social resiliency transferable to any geographic or temporal context.

Keywords: archaeological science,comparative osteology,bioarchaeology,zooarchaeology,bone histology,proteomics,isotope analysis
Mathematical and Numerical Modelling of Process-Structure Interaction in Fractured Geothermal Systems (MaPSI)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Norway
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-08-01
End date: 2026-07-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

In the development and production of high-temperature geothermal resources, large induced gradients in pressure and temperature during injection operations results in complex dynamics. This includes boiling of geothermal fluids and deformation of the fractured rock, dynamics that are currently not well understood. This provides a core motivation as well as challenging test cases for the mathematical and numerical developments in the MaPSI project. MaPSI has as its main objective to provide mathematical models and simulation technology required to assess subsurface process-structure interaction in the context of hydraulic and thermal stimulation in development and production of high-temperature geothermal resources. This will be achieved by a highly novel and timely research programme which will: - Combine new techniques with recently developed methodology by my own research group to develop unprecedented mathematical and numerical approaches to enable modelling of multiphase flow and phase-change in thermo-poroelastic media with fractures that may slip, deform and propagate; - Advance competences in the main scientific fields involved; and - Improve understanding of coupled processes in development and production of high-temperature geothermal systems towards sustainable exploitation of the resource. The project will provide new mathematical and numerical models along with open-source software that have capabilities in modelling of coupled process-structure interaction in fractured porous media that greatly exceed those of existing platforms. Specific case-studies will assess process-structure interactions for development and production operations in high-temperature geothermal systems, including superheated and supercritical regimes, providing timely contributions to further developments of these resources.

Keywords: computational geoscience,mathematical modeling,geothermal energy
EmpoweriNg (European) SME business model InnovatiON (ENviSION)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Research and Innovation actions
Countries involved: Spain,Austria,Malta,Finland,Lithuania,Slovenia,Finland,Netherlands,Netherlands,Netherlands
Call: Understanding and supporting business model innovation (H2020-INSO-2014, 2014)
Start date: 2015-02-01
End date: 2018-01-31
Duration (months): 36.0
Total project cost (EUR): 3095250.0
EU funding (EUR): 3095250.0
Participants: 12
Project status: CLOSED

Reaching the ambitions of the Europe 2020 and the Innovation Union requires much more than just technological innovations. In the academic community, Business Model Innovation (BMI) has for a long time been recognized as the key to improved competitiveness and innovativeness. However, BMI does not reach SMEs yet nor is there knowledge on how SMEs conduct BMI in practice. Empowering SMEs to conduct BMI requires new approaches. By leveraging existing networks and communities, we will gather examples, best practices and insights into Business Models (BM) from case studies from each and every European region or industry, complemented with insights from other leading countries worldwide. The BM vortex will thus generate an enormous and rich library of business models patterns and managerial structures, provided on a platform, to support SMEs in these communities. We will also develop innovative tooling and provide them on the platform to makes it easy for SMEs to develop, evaluate and plan new business models. The ENVISION consortium covers Northern, Western, Central, Eastern and Southern Europe. In each region a top-ranked academic institution in the field of BMI is present as well as innovative businesses that deliver smart and tailored BMI tooling and reach out to SMEs. We build on over a decade of joint work on BMI and BM tooling. We will build and maintain regional and thematic communities. In the communities, support is delivered to help SMEs transform and improve their BMs. The consortium also includes partners and associated partners that will realize our pan-European reach to SMEs: on a pan-European level (e.g., UAEPME and female entrepreneurs’ network), on a national and regional level (e.g., chambers of commerce, family business organizations and statistical offices). The consortium also has linkages to EIT/ICT Labs and the European Service Innovation Centre (ESIC).

Keywords: business model,business model innovation,communities,business model tooling,smes
Future Wireless Communications Empowered by Reconfigurable Intelligent Meta-Materials (META WIRELESS) (META WIRELESS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Austria,Spain,Germany,Spain,Italy,Italy,Finland,Sweden,Greece,France
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2020-12-01
End date: 2024-11-30
Duration (months): 48.0
Total project cost (EUR): 3995128.44
EU funding (EUR): 3995128.44
Participants: 12
Project status: SIGNED

Wireless connectivity has become a pillar of our society. The growth of wireless traffic is relentless, forecast to reach a staggering worldwide aggregate of 5,016 exabytes by 2030, along with bit rates of 1 Tb/s and new services related to sensing, localization, low-latency, and ultra-reliability. While the performance of wireless networks has improved phenomenally over the last decades, progress is by now pushing against fundamental limits and the mechanisms that have sustained these huge improvements are starting to falter. New evolutionary leaps are called for in order to ensure that the aforementioned forecasts can become a reality. To date, every wireless system has abided by the premise that the propagation radio channel is fixed by nature and cannot be tampered with, but only compensated through ever more sophisticated transmission/reception schemes. A potential evolutionary leap for 6G-and-beyond networks is to break free from the postulate that channels are uncontrollable factors. Serving such a vision, META WIRELESS pursues the disruptive idea of designing wireless networks by treating the environment itself as a quantity to be controlled and optimized. Precisely, the manipulation of the wireless environment can be made possible by incorporating reconfigurable intelligent surfaces. These are planar structures, made of meta-materials and electromagnetically discontinuous, which do not adhere to conventional reflection and diffraction laws; rather, they can modify in a controllable fashion the phase and wavefront of impinging radio waves. If deployed to coat objects, walls, or building facades, they could allow customizing in real time the electromagnetic response of environments. Making this vision a reality requires the training of a new generation of researchers and a multidisciplinary effort involving wireless communications, physics, electromagnetic theory, and computational learning, which are the ingredients that define the META WIRELESS project.

Keywords: wireless networks,beyond 5g,6g wireless networks,signal processing,resource allocation,channel modeling,channel estimation
Strong Modular proof Assistance: Reasoning across Theories (SMART)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Austria
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-03-01
End date: 2022-08-31
Duration (months): 66.0
Total project cost (EUR): 1449000.0
EU funding (EUR): 1449000.0
Participants: 1
Project status: CLOSED

Formal proof technology delivers an unparalleled level of certainty and security. Nevertheless, applying proof assistants to the verification of complex theories and designs is still extremely laborious. High profile certification projects, such as seL4, CompCert, and Flyspeck require tens of person-years. We recently demonstrated that this effort can be significantly reduced by combining reasoning and learning in so called hammer systems: 40% of the Flyspeck, HOL4, Isabelle/HOL, and Mizar top-level lemmas can be proved automatically. Today's early generation of hammers consists of individual systems limited to very few proof assistants. The accessible knowledge repositories are isolated, and there is no reuse of hammer components. It is possible to achieve a breakthrough in proof automation by developing new AI methods that combine reasoning knowledge and techniques into a smart hammer, that works over a very large part of today's formalized knowledge. The main goal of the project is to develop a strong and uniform learning-reasoning system available for multiple logical foundations. To achieve this, we will develop: (a) uniform learning methods, (b) reusable ATP encoding components for different foundational aspects, (c) integration of proof reconstruction, and (d) methods for knowledge extraction, reuse and content merging. The single proof advice system will be made available for multiple proof assistants and their vast heterogeneous libraries. The ultimate outcome is an advice system able to automatically prove half of Coq, ACL2, and Isabelle/ZF top-level theorems. Additionally we will significantly improve success rates for HOL provers and Mizar. The combined smart advice method together with the vast accumulated knowledge will result in a novel kind of tool, which allows working mathematicians to automatically find proofs of many simple conjectures, paving the way for the widespread use of formal proof in mathematics and computer science.

Keywords: proof assistants,premise selection,automated reasoning,logical encodings,proof advice
GRACE: Gender and Cultures of Equality in Europe (GRACE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain,Spain,Italy,Hungary,Poland,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2015, 2015)
Start date: 2015-10-01
End date: 2019-09-30
Duration (months): 48.0
Total project cost (EUR): 3719102.04
EU funding (EUR): 3719102.04
Participants: 10
Project status: CLOSED

The aim of the GRACE (Gender and Cultures of Equality in Europe) project is to systematically investigate the cultural production of gender equalities within Europe. Extending the success of GEMMA, the Erasmus Mundus ‘Masters of Excellence’ in Women’s and Gender Studies, the central objective of GRACE is to become the programme of reference for innovative interdisciplinary doctoral training for early career researchers. Previous scholarly work focuses on European gender equality policies. GRACE draws on innovative and interdisciplinary methodologies to investigate an under-examined aspect of those processes, namely the production of cultures of equality that underpin, enable and constrain those changing policy and legislative frameworks. Our methodological approach understands culture as neither normative frameworks nor ways of representing the world, but more fundamentally as the process through which people create the worlds they inhabit. The GRACE project will recruit, employ and provide advanced training for 15 ESRs who will research the production of cultures of gender equality across five specific sites where cultures of gender equalities are produced and contested by differently situated social agents. These five sites form the core of our research and training Work Packages, and are focused as follows: mediated cultures of gender equality (WP 1); urban cultures of gender equality (WP 2); intellectual and activist cultures of gender equality (WP 3); textual and artistic cultures of gender equality (WP 4); employing cultures of gender equality (WP 5). In sum, GRACE is designed to: equip the next generation of ESRs to play a leading role in developing advanced techniques for investigating the production of cultures of gender equality; translate creative and critical capacities into innovative cultural practices within and beyond academia; and enable them to take up positions as experts in producing new gender equalities cultures.

Keywords: gender,feminism,equality,cultures,transnationalism,interdisciplinary methodologies,employability