Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Progressive lighthouse districts serving as green district Gate towards Leadership in Sustainability (ProLight)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Innovation actions
Countries involved: Austria,Portugal,Greece,Spain,Italy,Belgium,Netherlands,Finland,Germany
Call: Social and affordable housing district demonstrator (IA) (HORIZON-CL4-2021-RESILIENCE-02, 2021)
Start date: 2022-10-01
End date: 2026-09-30
Duration (months): 48.0
Total project cost (EUR): 2896695.28
EU funding (EUR): 2667457.25
Participants: 17
Project status: SIGNED

European districts play a pivotal role in the achievement of a future low carbon economy. The envisaged actions of the ProLight project are representative for innovative refurbishment with large potential of immediate replication of other residential buildings from the municipalities & the social housing involved. ProLight assembles & closely integrates all needed actors & measures. The envisaged solutions will lead to better quality of life for all targeted end-users. This includes to find suitable social responses for awareness creation, up-take of knowledge, establishment of behavioral changes towards the energy efficient use & the integration of renewables within an appropriate local political frame. Analysed districts include: 1) Building and renovating in an energy and resource efficient way in AT, FI & GR, 2) Energy communities in ES, IT & PT combined in so-called Innovation clusters. A multi-actor approach uses a methodological concept that explicitly takes into account the energy transition as a societal lever for innovation in the involved demo districts. Applied research will be connected with theoretical analysis that involves identifying and compiling good practices, successful initiatives and exemplar real-world demo sites. These practices will be assessed and lead to a complete European competence framework, encapsulating the skills required to reach this change via recorded successful methods observed through ProLight. The project combines individual, gender & collective aspects of active and responsible citizenship in an integrated working concept, to conceptualize climate-aware citizens and communities. ProLight exploits the potential of this growing wave of civic engagement and citizen science, in order to facilitate the transition to green, sustainable societies & economies. ProLight achieves this by understanding, defining, measuring & assessing of 6 demo districts in different regions of Europe & disseminate effectively project results.

Keywords: integrated renovation,replication,municipalities and the social housing,social innovation in building and renovating,energy and climate aware communities
NOVEL PROCEDURES AND SUSTAINABLE GUIDELINES TO ENHANCE THE USE OF ALTERNATIVE FERTILISERS (NOVAFERT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Clean Environment and zero pollution
Action type: Coordination and support actions
Countries involved: Belgium,Croatia,Spain,Finland,Ireland,Poland
Call: Environmental impacts and trade-offs of alternative fertilising products at global/local scale. (HORIZON-CL6-2021-ZEROPOLLUTION-01, 2021)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 1998829.0
EU funding (EUR): 1998829.0
Participants: 9
Project status: SIGNED

In line with the Zero Pollution action plan, the “Farm to Fork” strategy and the new Fertilising Product Regulation, NOVAFERT will demonstrate the technical, economic, and environmental feasibility and safe use of a wide portfolio of at least 25 alternative fertilising products, containing recovered nutrients from all 6 different waste streams mentioned in the call, with the goal of facilitating the replacement of synthetic and mineral fertilisers. NOVAFERT gathers 9 multidisciplinary actors to demonstrate the technical, economic, and environmental feasibility and safe use of alternative fertilising products. The environmental aspect will be covered by developing guidelines and a consensual method for environmental assessment of alternative fertilising products. The economic aspect will be covered by co-creating novel, circular and green business models. As such, NOVAFERT will reduce environmental impacts and external nutrient dependence in agriculture in 6 representative countries from Eastern, Western, Northern, Southern and Central Europe. NOVAFERT will map existing alternative fertilising products across Europe and develop an Atlas of the nutrient-oriented living labs, and also will support the development of sustainable local value chains. By regionally contextualizing and interlinking all main recovering technologies and products, and technically connecting all value chains and key relevant stakeholders in 7 regional working groups and 7-10 lighthouse demo’s, NOVAFERT will foster the sustainable use and management of alternative fertilizing products in Europe. Moreover, NOVAFERT will develop a portfolio of support policies and legislative instruments suitable for local deployment in the EU regions through 7 specific action plans and 4 policy briefs. Thereby NOVAFERT will bring together the necessary information for efficient and safe utilizing of alternative fertilising products to help decision-making on valorisation employed in nutrient recovery.
mUltiscale IoT equipPed lonG linear infRastructure resilience built and sustAinable DevelopmEnt (UPGRADE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,China,Japan,Australia,Dominican Republic,Kazakhstan,United Kingdom,Spain,France,Sweden,Portugal,Ukraine
Call: MSCA Staff Exchanges 2022 (HORIZON-MSCA-2022-SE-01, 2022)
Start date: 2024-03-01
End date: 2028-02-29
Duration (months): 48.0
Total project cost (EUR): 1016600.0
EU funding (EUR): 892400.0
Participants: 19
Project status: SIGNED

Long linear infrastructure (LLIs) earthworks (e.g. road & railway slopes, pipeline bedding, flood protection structures) are more vulnerable to cascading and escalating failures, due to their topographically designed spanning length and long operational lives. With increasingly frequent severe weather conditions caused by climate change, maintaining a high level of safety performance, especially for the aged LLIs, remains a constant challenge, leading to an ever-increasing amount of investment in maintenance. Current knowledge about how these assets deteriorate over time and how deterioration affects risk and performance is patchy. The conventional engineering-oriented approach alone became insufficient to provide a solution to the complex problem like this. As we accelerate into the 21st century, the latest advances in technology, through digitalisation by integrating new revolutionary data technologies of Internet-of-Things (IoT) and artificial intelligence (AI), offer opportunities to UPGRADE our LLIs and achieve new heights in safety and performance. Highly-skilled researchers and practitioners, capable of dealing with such problems, are scarce and in high demand by both academia and industry. Therefore, formed with 11 world-leading research organisations and 6 companies across Europe, Asia and Oceania with expertise and facilities in Earth Observation, geomaterial testing, constitutive modelling, data mining, machine learning, uncertainty quantification, data-driven design and optic communication, UPGRADE aims to ensure comprehensive, robust and implementable solutions are obtained for LLIs resilience built and sustainable development. The network is carefully designed to enable research and innovation staff exchange across all aspects. UPGRADE secondees will enjoy a highly integrated, interdisciplinary and intersectoral staff exchange, sharing know-how and skills development environment through the planned secondments, networkwide events and local trainings.

Keywords: optic fibre communication risk assessment
Leveraging Artificial intelligence for Astrophysical Source parameter Estimation and Rapid electromagnetic follow-up with the future space-based Gravitational Waves Observatory (LASERGWO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany,Switzerland
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2029-08-31
Duration (months): 36.0
Total project cost (EUR): 393181.44
EU funding (EUR): 393181.44
Participants: 2
Project status: SIGNED

The Laser Interferometer Space Antenna (LISA), a milli-Hertz gravitational wave (GW) observatory, has extraordinary scientific potential. It is expected to revolutionize multimessenger astrophysics in the mid-2030s through synergies between LISA and both space- and Earth-based electromagnetic (EM) observatories. Mergers of supermassive black hole binary systems will be primary sources for these multimessenger studies. LISA will detect GWs emitted during the pre-merger phase and pinpoint the source location, allowing EM observatories with narrow fields of view to search for potential counterparts. For this synergy to be effective, rapid alerts of sky positions and coalescence timing are crucial—not only at the moment of merger but also in the hours leading up to it, when precursor signals may occur. This raises a vital question: what strategies or technologies will ensure that EM observatories are prepared to respond in nearly real time? My project addresses this urgent need by developing a low-latency alert pipeline (LLAP). Unlike detailed astrophysical analyses, which can be adjusted post-event, the LLAP must be operational from the start of LISA’s mission to enable prompt identification, analysis, and follow-up of transient events. This pipeline will leverage deep learning algorithms to process LISA’s raw phasemeter data and generate posterior parameter distributions for binary coalescences. This novel approach bypasses standard initial data processing stages, aiming to reduce alert latency for EM observatories. Moreover, it integrates data analysis tools and hardware, as the LLAP will be validated using experimental data from a Field-Programmable Gate Array-based LISA Delay Hardware Simulation developed at AEI Hannover. This experiment simulates onboard measurement chains and allows for real-time injection of GW signals during hardware testing. LASERGWO will pave the way for future multimessenger observations.

Keywords: lisa,gravitational waves,multi messenger astronomy,bayesian data analysis,low latency pipelines,deep learning,lisa hardware simulation,time delay interferometry,noise reduction techniques
Intracranial Neuro Telemetry to Restore Communication (INTRECOM)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Netherlands,Austria,Germany,Switzerland
Call: Tools to measure and stimulate activity in Brain Tissue (HORIZON-EIC-2021-PATHFINDERCHALLENGES-01, 2021)
Start date: 2022-12-01
End date: 2026-11-30
Duration (months): 48.0
Total project cost (EUR): 3997917.25
EU funding (EUR): 3997917.0
Participants: 5
Project status: SIGNED

Not being able to communicate while still being conscious is a horrifying prospective for many patients worldwide. Patients with motor neuron disorders, trauma or stroke risk losing complete muscle control leading to Locked-In Syndrome (LIS) which leaves them completely paralysed and unable to communicate. This is an intolerable, fearful situation with very low quality of life and extreme burden of care for patients, family, and care givers. Intracranial Neuro Telemetry to REstore COMmunication (INTRECOM) will provide a breakthrough for these patients by developing a novel, fully implantable Brain-Computer Interface (BCI) technology that allows for real-time speech decoding and use in the home environment. This BCI system will significantly transcend current technology by providing a high-resolution and sustainable device, combining state-of-the-art hardware and software solutions based on Artificial Intelligence (AI) to liberate LIS patients from their isolation.

Keywords: neural engineering,brain computer interface,electrocorticography,locked in syndrome,human,machine learning
Digitally-enabled FLEXible Industries for reliable energy grids under high penetration of Variable Renewable Energy Sources (VRES) (FLEXIndustries)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Innovation actions
Partnership: Processes4Planet (co-programmed)
Countries involved: Italy,Greece,Spain,Germany,Portugal,Türkiye,Poland,Bulgaria,Switzerland
Call: Design and optimisation of energy flexible industrial processes (Processes4Planet Partnership) (IA) (HORIZON-CL4-2021-TWIN-TRANSITION-01, 2021)
Start date: 2022-06-01
End date: 2026-05-31
Duration (months): 48.0
Total project cost (EUR): 17084536.66
EU funding (EUR): 12384507.0
Participants: 37
Project status: SIGNED

FLEXIndustries builds upon a holistic multi-disciplinary (device, process and value-chain) and multi-scale (operating, tactical and strategic) approach fostering its 6 multi-sector (automotive, biofuels, polymers, steel, fertilizers, pharmaceuticals) energy intensive industries design and deploy the most suitable Energy Efficiency Measures and Process Flexibility Methods for their industrial environments along with a positive impact onto their interconnection with the electrical & heating networks. FLEXIndustries develops and demonstrates a Dynamic Energy & Process Management Platform to monitor, analyse and optimize the most energy-intensive industrial processes, by managing properly emerging demand response mechanisms and providing plant and process flexibility as well as offering grid services. The unique premise of FLEXIndustries, is the optimal integration of i) innovative energy generation, storage and conversion assets (e.g., BESS and waste heat recovery solutions based on novel HPs, ORC and heat exchangers systems), ii) smart and digital tools for optimised operation and control, all supported by iii) novel business models and market mechanisms for enhanced industrial flexibility. Overall, FLEXIndustries has the potential to save: a) ≥ 159 GWh/ y of Primary Energy in total, b) ≥ 6.0 M€/y Life Cycle Costs on demo scale and c) ≥ 33,111 CO2-eq/y emissions at project level. Demonstration will take place in 6 industrial facilities in 5 reference countries (Turkey, Greece, Poland, Bulgaria, and Italy) and will feature: a) energy efficiency and operational flexibility along with process redesign/modification, b) increased levels of electrification, digitalisation and automation, c) enhanced user satisfaction and grid flexibility services, and d) decreased environmental footprint. A highly competent team of 16 Large Enterprises, 6 Research Institutes, 8 SMEs, 2 Universities and 3 Non-profit Organizations are assembled to ensure FLEXIndustries success

Keywords: industrial energy flexibility,digitalisation,waste energy valorisation,grid services,energy system integration,green industries,industrial demand response,process optimization
A NON-INVASIVE, ADAPTIVE DIGITAL THERAPEUTIC SOLUTION FOR POST-TRAUMATIC STRESS DISORDER AND OTHER MENTAL DISORDERS (GrayMatters for PTSD - GfP)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator Open 2021 (HORIZON-EIC-2021-ACCELERATOROPEN-01, 2021)
Start date: 2022-09-01
End date: 2025-05-31
Duration (months): 33.0
Total project cost (EUR): 3594250.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Post-traumatic stress disorder (PTSD) is a severe mental disorder, annually affecting 3.2% of the population with global market-size estimated at €7.5B. Current treatments’ success is marginal, costly, with severe side-effects. GrayMatters is the first to introduce a non-invasive digital-therapeutics device harnessing brain plasticity to help PTSD patients control abnormal brain-region activity. Our patented innovation uses machine-learning to convert EEG signal to an fMRI-like signal of the amygdala such that patients learn to self-control their amygdala activity level using affordable EEG-Neurofeedback device. Initial clinical-trials on stress-resilience & PTSD patients showed significant positive clinical results. The founders have 25+ years experience in commercialization, healthcare & technology with several startups exits/IPOs. LOIs includes top mental-institutes and world-renowned KOLs of PTSD psychiatry. GMH was recently chosen as 1 of 8 innovative companies by Nature magazine.

Keywords: ptsd,amygdala,post traumatic stress disorder,mental disorder,digital therapeutics device
Nidovirus Replication Complexes: How enzymes shape viral genomes (NidoRep)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: B iological  Mechanisms , Structures  and Functions
Panel description: For all organisms : Molecular biology , biochemistry, structural biology, molecular biophysics , synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1499779.0
EU funding (EUR): 1499779.0
Participants: 1
Project status: SIGNED

Nidoviruses are an intriguing group of +RNA viruses, whose diverse genome sizes (11-41 kb) reflect a long history of adaptation to suit specific niches. They remain mostly neglected, with the exception of the large-genome Coronaviridae (CoV) family (32 kb), which includes the notorious human pathogen SARS-CoV-2. At the other end of the size-spectrum is the small-genome Arteriviridae (ArV) family (11 kb), an understudied group of prevalent, animal-infecting pathogens. Viral replication is mediated by a suite of enzymes known as the replication transcription complex (RTC), at the core of which is the RNA-dependent RNA polymerase (RdRp) and its unique N−terminal domain, known as the NiRAN. NidoRep aims to bridge the prevalent knowledge-gap between small and large genome nidoviruses, by deciphering the specific structural and mechanistic features of the RTC that regulate genome replication across such vastly different viruses. It will be divided into three distinct objectives: Objective 1 will focus on small-genome nidoviruses, providing the first structural and functional characterization of an ArV RTC. Objective 2 will probe how RdRp speed and fidelity have been fine-tuned to accommodate the distinct and conflicting replication requirements of diverse nidoviruses. This will be achieved through the development of an innovative in vitro sequencing assay, also providing a new and robust tool for screening drugs that corrupt RNA synthesis. Objective 3 will investigate the role of the NiRAN in initiation of RNA synthesis though protein-priming, providing new insight into the functional evolution of this complex domain, while also identifying novel drug-targeting sites. NidoRep will determine how specific viral enzymes have structurally and functionally evolved to support remarkable genome diversification within a single viral order. It will expand our understanding of understudied viruses with epidemic potential, and guide drug design strategies against key viral targets.

Keywords: nidovirus,polymerase,rdrp,nucleotidyltransferase,niran,replication transcription complex,viral evolution,error rates,drug design,nucleotide analogues,coronavirus,arterivirus,sars cov 2,eav
Non-invasive patterned electrical neurostimulation of the retina (Outer-Ret)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Israel
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-04-01
End date: 2028-03-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Retinal implants remain one of the most demanding technologies in brain-machine interfacing. State of the art devices have yet to reach the needed performances. Main barriers are sub-optimal stimulation parameters and long development and testing procedures. While invasive approaches, have yet to achieve the resolution performances needed by million of patients blinded by retinal degenerative diseases, non-invasive approaches in the form of trans-orbital stimulation have received no attention, yet they offer potentially dramatically cheaper and easy to adapt and optimize technology. The main goal of this project is to advance the field of retina neurostimulation by developing new tools for the study and interfacing with the retina. In particular: (1) Bi-directional electrophysiological interface which can record and stimulate the intact retina (in the eye) and (2) soft multi-electrode arrays for non-invasive stimulation of the retina (soft trans-orbital electrodes) will be explored. We will use these tools to study the retina in its intact form (in animal models) and we will implement the gained know-how in humans to study non-invasive stimulation. In this project we will establish a new platform for bi-directional electrophysiological interfacing with the intact retina and we will use it to study the retina in its intact form. Such investigations have ground breaking nature as they can advance both the fundamental understanding of the retina and improve the manner by which we stimulate the retina to generate artificial vision: Specifically, we aim to record spontaneous waves activity and light sensitive ganglion cells, optimize electrical stimulation parameters in the intact retina, and ultimately to measure retina responses to trans-orbit stimulation. As the ultimate goal of the project, we aim to establish the foundation of trans-orbital stimulation as a new non-invasive paradigm for functional vision in patient suffering from retina degenerative diseases.

Keywords: neural interfaces,neuro engineering,retinal implants,soft electrodes,micro electrode arrays