Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Specific activities in the context of innovation support (HORIZON 2020) in the Free State Saxony (EEN SACHSEN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Germany,Germany,Germany,Germany,Germany
Call: Enhancing the innovation management capacity of SMEs (H2020-Adhoc-2014-20, 2014)
Start date: 2015-01-01
End date: 2016-12-31
Duration (months): 24.0
Total project cost (EUR): 193680.2
EU funding (EUR): 193680.2
Participants: 9
Project status: CLOSED

The aim of the present proposal is to contribute to the smart growth in the Free State Saxony as an emerging region in the European Union by increasing the efficiency and effectiveness of investments in research, development and innovation and by contributing to a better and more efficient connection of actors along the innovation chain. To achieve the above mentioned objectives the proposed project will: a) Identify bottlenecks to the creation of economic impact in companies benefitting from grants by Horizon2020's SME instrument and address these bottlenecks with the help of capable coaches. This service to beneficiaries of the SME instrument in the context of a giving project is called “Key account management”' (KAM). b) Increase the efficiency and effectiveness of innovation processes in small and medium sized enterprises with significant innovation activities that could potentially become beneficiaries of European support to research and innovation but would not have effective access to consulting services for innovation management. This service, which will be provided independently from a specific innovation project and focussing on a company's innovation management system, is called “Enhancing the innovation management capacity of SMEs” (EIMC). The project targets at the delivery of in total twenty 7-days service packages, five KAM and 15 EIMC services, in the geographical area of the Free State Saxony (Germany).

Keywords: innovation management capacity,key account management
Galera Cluster: World’s Most Advanced Technology to Protect Against Data Loss (GALERACLUSTER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Finland
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2017-10-01
End date: 2020-09-30
Duration (months): 36.0
Total project cost (EUR): 1752250.0
EU funding (EUR): 1226575.0
Participants: 1
Project status: CLOSED

In today’s born-digital world, transaction intensive businesses require data to be available more than 99,99% of the time. From only 5 minutes of data center downtime, companies can lose over €12.000. Several solutions have been put on the market, but they are behind expectations, due to no possibility to eliminate downtime during maintenance operations, sub optimal synchronization, update and communication, low resilience to network conditions and delays. Codership is a worldwide operating company, awarded by the MySQL community (2014 winner of Global and European Red Herring). We have been growing constantly, reaching revenues of €1.1million in 2016 and a client portfolio which includes Apple, Disney, Deutsche Telecom and Nokia. Our team of expert software developers, PhDs, and experienced management and marketing specialists has been developing Galera Cluster, since 2007 and marketing it since 2009. It is an easy-to-use high-availability solution with high system uptime, no data loss, and scalability for future growth. With this innovation project we are taking our technical solution one step further, including new developments to enable entering new markets (NoSQL/MongoDB, Microsoft), while expanding our existing MySQL business. Through pilot demonstrations with the industry, opening new commercialization channels and growing our team, we aim to secure position in EU, and expand to US, Asia and Australia. Galera Cluster is now the second most popular solution on the market, present in the Linux distributions of Red Hat, Ubuntu, Debian, SuSe and OpenStack distributions of DELL, IBM and Intel, and aims to become the world’s most advanced open source database cluster. Based on the recognition given to us by the ICT community and the explicit interest in our solution by reference providers such as Microsoft and Oracle, we believe that Galera could become the de-facto method for maintaining synchronized copies of large amounts of data for a variety of businesses.

Keywords: data protection,multi master cluster,synchronous replication,mysql,databases,new markets
Single-Atom Radio Frequency Fingerprinting (SARF)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Austria
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-04-01
End date: 2024-09-30
Duration (months): 78.0
Total project cost (EUR): 1998000.0
EU funding (EUR): 1998000.0
Participants: 1
Project status: SIGNED

Precise investigation tools for analyzing and manipulating matter down to the scale of single atoms are the eyes, ears and fingers of nanoscience and -engineering. SARF takes these nano-analytical "senses" one next step beyond the present state of the art. SARF is breaking new grounds by enabling spectral fingerprinting of single atoms for elemental identification and intra-molecular chemical analytics with sub-nanometer spatial resolution and operating in vacuum- as well as liquid-phase environments. This presently impossible combination of analytical capabilities simultaneously in a single tool is highly desirable to many diverse fields of nanoscience and technology, where decisive functionality originates from single individual atoms and molecules (e.g. spintronics, sensors, catalysis, medicinal drug development, surface physics, biology, etc.). SARF realizes resonance spectroscopy at giga-Hertz frequencies combined with scanning tunneling microscopy for specific single-atom fingerprinting. Characteristic resonance signals are locally detectable by the probe tip as small changes of conductance that indeed enable elemental and chemical identification. SARF conceives and develops single-atom fingerprinting on a manifold of different systems including magnetic and nonmagnetic metals, semiconductors and, exemplarily, tetrapyrrole-based metal-organic functional molecules. If successful, SARF will provide a controlled, versatile, fast and readily applicable "atom-by-atom" matter analysis, where single atoms are selected and identified one by one in real time and space.

Keywords: single spin spectroscopy,radio frequency scanning tunneling microscopy,magnetic resonance
Impact of diatom evolution on the oceans (DEVOCEAN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Sweden
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-10-01
End date: 2026-03-31
Duration (months): 78.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Motivated by a series of recent discoveries, DEVOCEAN will provide the first comprehensive evaluation of the emergence of diatoms and their impact on the global biogeochemical cycle of silica, carbon and other nutrients that regulate ocean productivity and ultimately climate. I propose that the proliferation of phytoplankton that occurred after the Permian-Triassic extinction, in particular the diatoms, fundamentally influenced oceanic environments through the enhancement of carbon export to depth as part of the biological pump. Although molecular clocks suggest that diatoms evolved over 200 Ma ago, this result has been largely ignored because of the lack of diatoms in the geologic fossil record with most studies therefore focused on diversification during the Cenozoic where abundant diatom fossils are found. Much of the older fossil evidence has likely been destroyed by dissolution during diagenesis, subducted or is concealed deep within the Earth under many layers of rock. DEVOCEAN will provide evidence on diatom evolution and speciation in the geological record by examining formations representing locations in which diatoms are likely to have accumulated in ocean sediments. We will generate robust estimates of the timing and magnitude of dissolved Si drawdown following the origin of diatoms using the isotopic silicon composition of fossil sponge spicules and radiolarians. The project will also provide fundamental new insights into the timing of dissolved Si drawdown and other key events, which reorganized the distribution of carbon and nutrients in seawater, changing energy flows and productivity in the biological communities of the ancient oceans.

Keywords: diatom,past oceans,silica,mesozoic
Transforming Norms Research through Practices: Weaponised Artificial Intelligence, Norms, and Order (AUTONORMS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Denmark
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-08-01
End date: 2025-07-31
Duration (months): 60.0
Total project cost (EUR): 1499759.0
EU funding (EUR): 1499759.0
Participants: 1
Project status: SIGNED

Weapons systems with an increasing number of autonomous features are emerging as revolutionary technologies of war. In particular, this concerns systems with autonomy in their critical functions that relate to selecting and engaging targets without human input. This weaponisation of Artificial Intelligence (AI) signals the looming absence of meaningful human control in warfare, which has become a central focus of the debate on autonomous weapons systems (AWS). Here, states either seek to introduce new norms governing AWS or to leave the field open in order to increase their room of manoeuvre. These uncertainties make monitoring to what extent AWS will shape and transform international norms governing the use of force a matter of great importance. But existing International Relations research on norms despite producing excellent critical work does not yet enable us to understand the dynamics of this vital process because it does not capture adequately how norms emerge and develop. The state of the art conceptually connects norms predominantly to international law and limits attention to how norms emerge in deliberative international forums. Instead, the AUTONORMS project will develop a new ground-breaking theoretical approach that allows us to study how norms, understood as standards of appropriateness, manifest and change in practices. Taking this bottom-up perspective, we will monitor norm emergence and change across four contexts of practices (military, transnational political, dual-use, and popular imagination) in four countries (USA, China, Japan, Russia). This flexible portrayal allows us to adequately understand how norms related to AWS will develop, as well as considering the impact such emerging norms have on the current international security order of which norms are constitutive building blocs. The project thus provides an innovative analytical model for studying uncertain processes of technological innovation associated with the AI revolution.

Keywords: norms,practices,international security,autonomous weapons systems,constructivist international relations theory,world order,technological innovation,artificial intelligence
Rapid heat inactivation of pathogens to enable biomarker research (RIPEB)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Sweden
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-1-2015, 2015)
Start date: 2015-07-01
End date: 2015-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The risk of epidemics due to infectious diseases caused by pathogens is an immense global challenge. The need for rapid development of vaccines, antiretroviral drugs and treatment schemes is at the top of most countries’ and organizations’ agenda. Performing biomarker research on infectious diseases is an important research area to understand and monitor disease state and progression as well as enable diagnosis and vaccine- and drug development. The project aim is to further develop and verify the Stabilizor system to enable complete inactivation of pathogens, while still preserving sensitive biological biomarkers, in a rapid and secure manner. By preserving sensitive biomarkers early on in the analytical workflow, researchers will be able to conduct more efficient and reliable biomarker research. This will enable an accelerated process of developing vaccines and antiretroviral drugs, especially in the exploratory- and pre-clinical stages where identifying and assessing disease targets and biomarker candidates is the main focus. Also, this would allow for safe transportation of infected samples from the collection site in-field or between different laboratories to facilitate proper analysis. This will have profound social- and economic impact globally. This is of particular interest for research on highly contagious pathogens where extensive biocontainment precautions are required in enclosed laboratory facilities such as BSL-3 and -4 laboratories. Denator’s Stabilizor system preserves the quality of biological samples from the moment of excision allowing researchers to confidently identify and verify potential biomarkers. The novelty lies in the ability to rapidly heat inactive tissue samples (within 60 seconds) to achieve both complete pathogen inactivation and ensure biomarker stability. A first customer has demonstrated complete inactivation of several infectious pathogens which is a strong proof-of-concept for the applicability of the system.

Keywords: pathogen inactivation,heat inactivation,virus,bacteria,infectious diseases,proteomic analysis
NICENAV Navigation-grade ITAR-free Certifiable Equipment for the Navigation of manned and unmanned Air Vehicle, based on FOG technology (NICENAV)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Italy,Italy
Call: Small business innovation research for Transport (H2020-SMEINST-1-2015, 2015)
Start date: 2015-06-01
End date: 2015-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

Brief description of project idea: NICENAV project (Navigation-grade ITAR-free Certifiable Equipment for the Navigation of manned and unmanned Air Vehicle, based on FOG technology). Fiber Optic Gyroscope (FOG) is a truly and unique solid state technology that allows compact, lightweight and accurate sensors technology to provide orientation and position with or without GPS availability. The INS (Inertial Navigation Systems) proposed is an autonomous system that can operate in absence of GPS and is essential for airborne application where safety is involved (i.e. the system provide heading, altitude and position autonomously in case of GPS lost). NICENAV does not rely on any component or design/development services or technical data to be provided by US under the ITAR regulations; this ensures shorter time-to-market and reduced development costs. It will be qualified to be installed on-board of airborne platforms, both manned and unmanned, where safety requirements (DO-178C/DO-254) are mandatory. The system will provide performance better than 1 NM/hr for the “inertial navigation” accuracy Competition: Sagem (French company) that offers an ITAR-free INS solution dedicated to high performance airborne applications, which is also DO-178C & DO-254 certified. Comparing the two products, NICENAV has a lower cost (about 20%) and it is based on FOG technology while the Sagem solution is based on RLG technology. FOGs are more reliable, need lower maintenance, ensure an higher MTBF (Mean Time Between Failures) and they are easily scalable. In addition, contrary to RLGs, FOGs are very close to their theoretical performance Market segment: World Wide Aircraft Prime Contractors - Avionics first and second tier integrators - Aircraft Maintenance&Overhaul Companies Market size: Focusing on ITAR-free solutions: $192 million in 2014 and $238 million by 2019 Revenue Streams: Cumulated revenues at the 4rd year after commercialization = € 29M Team: CIVITANAVI SYSTEMS-NEAT

Keywords: inertial navigation system,fiber optic gyro technology,itar free,inertial measurement unit,civil aviation,world wide aircraft prime contractors
Computational Neurophenomenology: Explaining Concious Experiences in terms of Neural Mechanisms (CONSCIOUS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Netherlands,United Kingdom
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2022-01-01
End date: 2028-03-31
Duration (months): 75.0
Total project cost (EUR): 2436768.0
EU funding (EUR): 2388443.0
Participants: 2
Project status: SIGNED

How do conscious experiences depend on the brain? The CONSCIOUS project aims to make new progress on this oldest of questions by progressing from establishing correlations between patterns of brain activity and aspects of consciousness, towards developing and testing explanations in terms of neural mechanisms. By following this strategy, I believe the problem of consciousness will be dissolved rather than outright solved – similar to what happened with the study of life, decades ago. One branch of CONSCIOUS will explore what it is like to be conscious ‘at all’. Here, I will make use of the concept of ‘emergence’ – the sense in which a system’s whole can seem to be more than the sum of its parts. I will test the idea that the globally unified character of conscious experiences emerges from neural dynamics, in a similar way to how a flock of birds emerges from the trajectories of the individual birds that make it up. This will involve developing new theoretically principled and practically applicable measures of emergence, and applying them to neurophysiological data reflecting different global states of consciousness. A second branch will explore the nature of specific conscious perceptions, appealing to the influential idea of the brain as a ‘prediction machine’. Here, I will develop novel machine learning models to investigate how particular conscious experiences can be understood as arising from the brain’s ‘best guesses’ of the causes of its sensory inputs. I will use combinations of behavioural experiments and neuroimaging to test the idea that different kinds of neurally-encoded predictions can account for different kinds of perceptual experience. CONSCIOUS is thoroughly multidisciplinary, bridging cognitive neuroscience, philosophy, statistical physics, machine learning, and artificial intelligence. It is only through such an approach that it is possible to make substantial progress towards a satisfying scientific account of conscious experience.

Keywords: emergence,predictive processing,active inference,machine learning,artificial intelligence,phenomenology
Professional cross-priming for ovary and prostate cancer (PROCROP)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Spain,Switzerland,Netherlands
Call: New therapies for chronic non-communicable diseases (H2020-PHC-2014-two-stage, 2014)
Start date: 2015-09-01
End date: 2021-02-28
Duration (months): 66.0
Total project cost (EUR): 7572500.0
EU funding (EUR): 5750000.0
Participants: 7
Project status: CLOSED

Immune responses are initiated by antigen presentation mediated by dendritic cells (DC). There is a minority subset of DC highly specialised in starting up cytotoxic T lymphocytes able to kill tumor cells. PROCROP aims to develop in three pilot clinical trials a suitable individualized cancer vaccine technology for castration resistant prostate cancer and metastatic cancer of the ovary that would complement currently available therapies to increase efficacy. The project applies recent compelling knowledge on the identity of the main antigen-presenting DC subsets for vaccine elicitation of cytotoxic T lymphocytes endowed with the ability to seek and destroy tumour cells (such immune mechanism is termed crosspriming). This unique opportunity for superior DCs for immunotherapy comes from the fact that Miltenyi, a successful European biotech company, has the necessary proprietary reagents (anti-BDCA-3 monoclonal antibody and immunomagnetic selection technology), as well as the expertise to clinically develop a strategy of DC isolation and short-term cell culture for immunotherapy. From the point of view of the tumor antigens, processed autologous tumor material will be mixed with defined common tumor antigens in the form of recombinant proteins. This novel combination will permit stronger and broader antitumor immune responses and more accurate monitoring of the ensuing immunity against the tumors. These features should make the novel DC vaccine more efficacious than the currently US-approved DC vaccine PROVENGE and other DCs preparations undergoing trials, such as those derived from monocytes. Three of the leading groups in immunotherapy of cancer in Europe would join forces to develop this individualized cell therapy technology in clinical trials for two highly prevalent and unsatisfactorily managed malignant conditions. Industrial partnership provides the unique advantage of producing a rigorously standardized product for eventual multicentre trials.

Keywords: immunotherapy of cancer,cell therapy,dendritic cell,crosspriming