Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Eco-sleeve is a propellant-free technology for Aerosols, generating high pressure to provide the familiar consumer experience of continuous dispensing. (Eco-sleeve)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Israel
Call: Boosting the potential of small businesses in the areas of climate action, environment, resource efficiency and raw materials (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-08-01
End date: 2018-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Aerosol dispensers are widely used, with more than 15B unit sold annually worldwide, 37% in Europe alone. Despite the fact they are very effective and convenient, they are raising a big environmental issue for their impact on greenhouse effect and CO2 footprint. Resulting extensive legislation on the subject, mainly in Europe, which restricts their use. Eco-Sleeve project goal is to address the highly significant ecological, social, and economic problem caused by the frequent use of aerosols products on a day to day bases. The Eco-sleeve generates the high pressure required to provide the familiar consumer experience of continuous dispensing. This eliminates the need for gas as a propellant and the requirement to use cylindrical, metal pressure containers. GreenSpense’s product delivers the desired consumer experience while it – • Contributes to a cleaner environment by eliminating harmful gases and coatings, and reducing carbon emissions and greenhouse effect; • Enables the use of lower cost, recyclable packaging materials such as plastic, cardboard, and biodegradables, instead of metal canisters; • Reduces the cost of aerosols and continuous dispensers; and • Enables creative packaging design of continuous dispensers, replacing the traditional cylindrical shape; To deployment success, we have prepared a detailed work plan, which will be split into two stages: (i) Phase I, where we will dedicate six months to complete the technical, commercial, and financial feasibility analysis of Eco Sleeve, and (ii) Phase II, with up to 18 months to finalize design of a fully automated assembly machine and launch the product into the EU market. Europe is the largest manufactures of aerosol products in the world, with more than 1000 production plants and about 5.5 billion aerosol units per year. In order for the EU to comply with standards and maintain its global positioning on that issue, it requires to implement innovative technologies such as the Eco-Sleeve.

Keywords: propellant free,eco sleeve,pressure containers,aerosol,environment,carbon emission,greenhouse effect,recyclable packaging,packaging design,resource efficiency,row materials
Advanced pulmonary vascular monitoring for optimum Nitric Oxide delivery in acute respiratory distress syndrome. Expanding Nitric Oxide applications (OPVANOX-ARDS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-01
End date: 2020-04-30
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

Acute respiratory distress syndrome (ARDS) is the most severe form of respiratory failure. Pulmonary vascular dysfunction during ARDS increases mortality and therapies focused in improving pulmonary vascular mechanics could improve patient prognosis. Inhaled Nitric Oxide (NO), improves pulmonary vascular mechanics, but despite of this effect, has not proven to improve outcomes in ARDS. One of the most representative problems is the lack of information of the quantitative dose used and all consequences that this uncontrolled administration entails. In this project we aim to establish bedside physiologic variables and algorithms to guide efficient NO delivery during ARDS. It will involve the collaboration between an enterprise that has developed a new NO delivering system and is looking for expanding its applications and a researcher with expertise in physiology, imaging and biologic variables monitoring. As a result of this collaboration, the company will gain a quantitative way of determining the treatment efficiency that could be used in this and other applications, a more patient-oriented and physiology-focused approach for this product and the researcher will acquire skills for turning his career from the academy to the industry side. This research will combine edge technology to define bedside tools for patients monitoring with the application of this information for improving the performance of the delivery system. Clinically relevant imaging tools such as Magnetic Resonance Imaging and Positron Emission Tomography, and pulmonary artery pressure waveform advanced analysis as well as other non or minimum invasive tools will be studied in animal models. Software, algorithm or dedicated products will be proposed for incorporation into the gas delivery system or clinical monitors for improving patient safety. We are expecting a clear benefit to emerging European-based technologies that make our companies more competitive and well-positioned in a worldwide business.

Keywords: nitric oxide,acute respiratory distress syndrome,patient safety,pulmonary hemodynamics
Driving next generation autophagy researchers towards translation (DRIVE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Germany,Germany,Spain,Israel,Ecuador,Germany,Spain,Spain,Norway,Finland,Finland,Norway,Sweden,France,France,France,Netherlands,United States,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2017-11-01
End date: 2022-04-30
Duration (months): 54.0
Total project cost (EUR): 3890064.96
EU funding (EUR): 3890064.96
Participants: 35
Project status: CLOSED

The manipulation of autophagy has an enormous therapeutic potential to revolutionize the way we currently treat cancers, neurodegenerative disorders, inflammatory and infectious diseases. Despite the great promises made by pioneering medical studies, the still limited applied research on autophagy has hampered the translation of fundamental knowledge into clinical-grade products and improved healthcare. Applied autophagy research is essential to understand the roles of autophagy in the different physiological and pathological situations, to generate (disease) models and develop biomarkers and assays to assess its progress. The goal of the ETN Driving next generation autophagy researchers towards translation (DRIVE) is to train young scientists to fill this gap. DRIVE will equip its ESRs with an unique combination of knowledge and experimental expertise that are brought together in this consortium by the different partners. The realization of their projects in applied autophagy research will benefit of an exceptional interdisciplinary platform integrating cell biology, biochemistry, molecular biology, genetics, chemistry and “omics” approaches. In addition, DRIVE ESRs will acquire competencies to exploit the results for the development of products and techniques of commercial value. These ESRs will also be trained in disseminating results and knowledge through modern channels of communication.

Keywords: autophagy,biomarkers,assays,in vivo models,applied research,physiology,pathology
Spectral Imaging Powered Ship Hull Biofouling Detection and Cleaning (SleekShip)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Israel,Cyprus,Greece,Greece,France
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2019)
Start date: 2020-04-01
End date: 2022-07-31
Duration (months): 28.0
Total project cost (EUR): 3088475.0
EU funding (EUR): 2362038.14
Participants: 5
Project status: CLOSED

Marine biofouling has a tremendous economic and environmental impact; it can lead to >€1m in lost revenue per ship per year in fuel overconsumption alone. The International Maritime Organization estimates that gas emissions may increase between 38% and 72% by 2020, unless corrective measures are taken. The only way to mitigate biofouling is to detect it at an early stage (Level of Fouling – LoF 1), while it can still be cleaned with soft methods that do not damage hull paint or coating. With current approaches this is impossible, particularly within port waters as they are heavily turbid and inhibit visibility. Inspections outside port waters induce charter-off time that costs >€20k per day and are thus avoided by ship operators. SleekShip comprises a Semi-Autonomous Underwater Vehicle (SAUV) carrying a hyperspectral camera that captures light wavelength bands where light backscattering is less and the slime is easier to distinguish despite contamination. The inspection can take place in port waters while the ship is docked for other operations thus no additional charter-off time is incurred. An integrated cavitation-based cleaning tool allows for 100% paint-safe cleaning. By detecting biofouling early, ship owners will be able to achieve >€1.3m savings per vessel annually by reducing fuel overconsumption and paint/coating damage caused by hard-brush cleaning. Our consortium comprises SubseaTech, a dynamic manufacturer of underwater robots, QCELL, a high-tech SME specialising in hyperspectral imaging, M.Danchor a leading cleaning and inspection services company, TWI, the global leader in image-based underwater inspection technologies and Danaos, a NYSE-listed containership owner. Through SleekShip we aim to achieve sales of €41m, generating €17.9m profits and >110 jobs while helping the shipping industry save €3.4bn per year and reduce CO2 emissions by 115m tonnes over the 5 years after market launch. The Net Present Value ROI is 4:1 on EC funds with a grant.

Keywords: marine biofouling management,biofouling detection,biofouling removal,semi autonomous underwater vehicles,underwater robotics,hyperspectral imaging,cavitation based cleaning
Mass spectrometry for the characterization of micro- and nanoplastics (MS4Plastics)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2025-03-22
Duration (months): 24.0
Total project cost (EUR): 178320.0
EU funding (EUR): 178320.0
Participants: 1
Project status: SIGNED

The goal of MS4PLASTIC project is to open up new frontiers in the sample pre-treatment and pre-concentration protocols, as well as characterization of low µm-range microplastics and nanoplastics (1nm-20µm) in edible fish and shellfish samples by new, cutting edge methods being ICP-mass spectrometry operated in (i) single-event mode for the ultra-fast monitoring of transient signals and (ii) smart hyphenation strategies, combined with size-based fractionation techniques, such as size exclusion chromatography and field flow fractionation, as well as pyrolysis–gas chromatography–mass spectrometry. The achievement of these goals requires a multidisciplinary and complementary approach including analytical chemistry, instrumental methods, and nanometrology – all of which are part of the research conducted at the Flemish Institute for Technological Research (VITO), Belgium, who will readily engage all its resources and mobilize its international partnerships. This fellowship will focus on a wide range of transferable and scientific skills and involve carefully planned dissemination, exploitation and communication activities that will reinforce the fellow, the host institution, the scientific community, regulatory agencies, industry, and public worldwide. Importantly, this project will provide fellow the interdisciplinary expertise and allow her to be in a strategic position of maturity to design, lead and deliver high-impact future research projects; and be recognized as a leading expert for academic and non-academic sector.

Keywords: single particle inductively coupled plasma mass spectrometry,pyrolysis gas chromatography mass spectrometry,microplastics,nanoplastics,analytical separation and detection techniques
Accelerated Development of Appropriate Patient Therapies: a Sustainable, Multi-stakeholder Approach from Research to Treatment-outcomes - Sofia ref.: 115890 (ADAPT-SMART)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Public-private partnerships
Destination: Innovative Medicines Initiative 2
Action type: Coordination and support actions
Partnership: IMI2 (Art-187)
Countries involved: Germany,Germany,Germany,Italy,Belgium,Switzerland,Switzerland,Belgium,Sweden,France,France,France,France,United States,Netherlands,Netherlands,Luxembourg,United Kingdom,Denmark,Denmark,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Enabling Platform on Medicines Adaptive Pathways to Patients (H2020-JTI-IMI2-2015-04-two-stage, 2015)
Start date: 2015-07-01
End date: 2018-04-30
Duration (months): 34.0
Total project cost (EUR): 4064146.0
EU funding (EUR): 1130000.0
Participants: 35
Project status: CLOSED

Progress in the life sciences and related technologies offer great potential for therapeutic benefits to patients in need. However, major adaptations to current paradigms of bringing medicines to patients are required in order to realize that potential and to address important challenges in the healthcare ecosystem. Against this background, several initiatives are exploring new pathways to market, collectively referred to as Medicines Adaptive Pathways to Patients (MAPPs). The ADAPT-SMART consortium is aligning a limited number of major stakeholders eager to progress towards MAPPs implementation. It will act as a neutral collaborative platform that will engage industry, SMEs, regulators, Health Technology Assessment bodies (HTAs), payers, governments, clinicians and patients. The ADAPT-SMART consortium will contribute to align understanding of the impact of MAPPs, to share learnings between all stakeholders, and to allow the field to actively work towards MAPPs implementation. The impact of the ADAPT-SMART CSA will be a result of the delivery of • actionable advice/recommendations to IMI on how to best leverage results from past/current projects; • concrete proposals for future (IMI) projects; • actionable advice/recommendations and information to other actors in the healthcare environment; • synthesis of learnings from pilot projects and case studies with relevance to MAPPs; • communication of CSA outcomes by way of publications and conference presentations. This CSA will increase the probability of successful implementation of MAPPs and accelerate access to crucial therapies, thus improving the position of both the patients in need of novel treatments and the research-based pharmaceutical industry.

Keywords: adaptive design,regulatory,reimbursement,r and d models,pathways,multi stakeholder,collaboration
Quality and Production Control with Integrated Machine Vision (QualiLine-C-2.0)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Hungary
Call: Accelerating the uptake of nanotechnologies, advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-2-2014, 2014)
Start date: 2015-05-01
End date: 2017-04-30
Duration (months): 24.0
Total project cost (EUR): 1903750.0
EU funding (EUR): 1332625.0
Participants: 1
Project status: CLOSED

Our company, Falcon-Vision was established in 1996 with the aim of developing machine vision tools for the inspection of casted parts. During this time we have produced a number of custom inspection tools that can achieve 100% inspection without contact in real time. We have developed a successful track record and have become established as a supplier of high speed quality control and in-line metrology systems to leading multinationals (Nemak, Daimler, Sanofi, Epcos, Visteon) who produce parts for leading automotive companies (GE, AUDI, Renault, BMW, VW). Our custom-made inspection machines have been a huge success and our sales have increased from 1.2 million Euros in 2009 to 2.2 million Euros in 2013 and will be almost doubled in this year. This increase is not surprising based on our high quality products and the list of satisfied customers; however we are striving to increase the sales and satisfy the rising demands due to our machines being custom made. Recently, our customers’ demands have been also widening. They are requiring faster, simpler and more flexible measuring machines. After discussions with our customers we have come to the conclusion that the best way to increase our productivity and satisfy more customers would be to make our system modular which would help the customer pick and choose the different inspection modules in a flexible and efficient way. This would mean we can mass produce the modules which would speed up the service and reduce the price. In addition, development of new innovative modules is also foreseen to further improve the accuracy and to give the opportunity to inspect such geometries which were not possible in the past. The new modular approach will help halve the production lead time of the inspection machine and also reduce the cost by 30%.

Keywords: machine vision,automotive suppliers,in line inspection system,modular system,reduced design and production time and price,international expansion,growth of global market share
The Medieval and Early Modern Nautical Chart: Birth, Evolution and Use (MEDEA-CHART)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Portugal
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-06-01
End date: 2023-05-31
Duration (months): 72.0
Total project cost (EUR): 1231319.0
EU funding (EUR): 1231319.0
Participants: 1
Project status: SIGNED

Of all the technical and scientific developments that made possible the early modern maritime expansion, the nautical chart is perhaps the least studied and understood. This fact is very surprising as it was through those charts that the newly discovered world was first shown to the amazed eyes of the European nations. Although the History of Cartography is a well-established academic discipline and old charts have been examined for many years, their detailed technical study is still in its infancy. What is the origin of the pre-Mercator nautical chart, how charts evolved technically over time and how they were used at sea are all critical questions that remain to be answered. I intend to approach these challenges in a truly interdisciplinary way, by using innovative and powerful tools as a complement to the traditional methods of historical research: analytical cartometric methods, numerical modelling and the examination of the manuscripts through special lighting. By applying these tools to a large sample of charts of various periods and origins, I aim to unveil hidden graphic content related to their construction and use, to characterize their main geometric features, to establish meaningful connections with contemporary navigational methods and exploration missions, and to numerically simulate their construction by taking into account the explanations given in the textual sources. The effectiveness of those techniques has already been demonstrated in my previous studies, such as in the solution of an historical enigma which had been alive for more than a century: the construction of the Mercator projection, in 1569. Now, I propose to handle a broader and more complex set of questions, which has eluded the historians of cartography for even a longer period. The clarification of these issues will have a ground-breaking impact, not only in the strict field of the History of Cartography, but also in the context of the intellectual history at large.

Keywords: portolan chart,latitude chart,plane chart,cartometric analysis,cartometric modelling,history of cartography,history of navigation
Strengthening research in the Croatian Geological Survey: Geoscience-Twinning to develop state-of-the-art subsurface modelling capability and scientific impact (GeoTwinn)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Croatia,Denmark,United Kingdom
Call: Twinning (H2020-WIDESPREAD-05-2017-Twinning, 2017)
Start date: 2018-10-01
End date: 2022-01-31
Duration (months): 40.0
Total project cost (EUR): 996717.5
EU funding (EUR): 996717.5
Participants: 3
Project status: CLOSED

This proposal addresses the need to spread excellence and widen participation across the European Union by the twinning of research institutions. We propose to twin the Croatian Geological Survey (HGI-CGS) with two world-leading geoscience research institutes, the Geological Survey of Denmark and Greenland (GEUS) and the British Geological Survey of the United Kingdom Research and Innovation (BGS-UKRI), to significantly strengthen HGI-CGS’s research, and in a number of areas transform its capability. The overarching objective is: to deliver a coordinated and targeted programme of training, knowledge exchange and collaboration, involving world-leading experts, to embed cutting-edge research techniques, tools and knowledge within HGI-CGS, leading to a significant and measurable improvement in their geoscientific research capability. HGI-CGS will benefit from a range of research tools, technologies, software and methods at the disposal of GEUS and BGS-UKRI. However, central to this project is the development of active collaboration and partnership between people; between talented scientists within HGI-CGS and highly productive scientists within BGS-UKRI and GEUS, who in a number of cases are world-leading experts in their field. Through close collaboration of scientists working on a range of geoscience topics, facilitated through scientific workshops, two-way scientific exchanges and bespoke training programmes, the project will support HGI-CGS to strengthen research in four important geoscience subject areas, which are at the core of most world-leading geological surveys and geological research institutes: (i) 3D geological surveying and modelling; (ii) groundwater flow and contaminant transport modelling; (iii) geological hazards; (iv) geothermal energy. The project will also enhance research and innovation related to environmental issues: a shift to a low-carbon economy, climate change adaptation and risk management, environmental protection and resource efficiency.

Keywords: stimulating scientific excellence,scientific capacity building,collaboration,training,3d geological modelling,groundwater resources,geohazards,geothermal energy,sustainable environment