Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
In Vivo Observation of Transcriptional Regulation in Bacilli by Fluorescence Correlation Spectroscopy (INVIVOTRNSREG)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IIF-2008, 2008)
Start date: 2010-05-01
End date: 2011-09-30
Duration (months): 17.0
Total project cost (EUR): 166011.55
EU funding (EUR): 166011.55
Participants: 1
Project status: CLOSED

This application proposes the study of transcriptional regulation in Bacillus subtilis by direct, in vivo, observation using state-of-the-art two-photon fluorescence correlation spectroscopy. The project involves the study of two transcriptional repressors from B. subtilis, CggR and CcpN. Much work has been done in vitro on CggR and CcpN (Zorrilla et al, 2007a; Zorrilla et al, 2007b; Zorrilla et al, 2008a; Zorrilla et al, 2008b) since their discovery in the sequencing of the B. subtilis genome(Kunst et al, 1997). Both transcriptional repressors control opposite directions in the carbon metabolic cycle in gram positive bacteria through the production of metabolic enzymes. We propose to directly observe transcriptional regulation in vivo at the single molecule level. Using genetically engineered strains of B. subtilis, containing fluorescent protein fusions with CggR, CcpN and related factors under native promoters, we will apply the techniques of point and scanning two photon fluorescence correlation spectroscopy (FCS and sFCS) and raster image correlation spectroscopy (RICS). We will elucidate mechanisms of transcriptional regulation that cannot be observed by in vitro investigation.

Keywords: biochemistry,metabolism,molecular biophysics,fluorescence microscopy,single molecule biophysics,transcriptional regulation,gene expression,correlation spectroscopy,resonance energy transfer
Hybrid organic-inorganic nanostructures for photonics and optoelectronics. (ICARUS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Greece,Switzerland,Italy,United Kingdom,Germany,United Kingdom
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-12-01
End date: 2013-11-30
Duration (months): 48.0
Total project cost (EUR): 2803715.13
EU funding (EUR): 2803715.13
Participants: 8
Project status: CLOSED

The proposed ITN will support close collaboration between 8 highly experienced and complementary European teams, who in all cases are working at the forefront of semiconductor science, photonics and materials technology. The real value that is offered by our collaboration will be realized by the generation of new, genuinely disruptive hybrid-semiconductor optoelectronic technologies. It will also train the next generation of scientists at the highest level, producing a skilled cadre of researchers who will contribute the Europe’s competitiveness in emerging optoelectronic technologies. Our network has world-leading experience in the field of structure fabrication and material synthesis (both organic and inorganic), together with a strong focus in ultra-fast spectroscopy, nano-optics, photonics, non-linear optics and device engineering. We also have a significant experience in high-level theoretical analysis of the optical properties of organic and inorganic semiconductors, as well as experience in industrial research. The establishment of ICARUS will thus realize the creation of new hybrid systems, their characterization and their implementation in photonic and optoelectronic devices.

Keywords: physical sciences,nanotechnology,photonics,photovoltaics,hybrid,spectroscopy,semiconductors,organic,inorganic,microcavities,nanocrystals
Fast Analog Computing with Emergent Transient States - Initial Training Network (FACETS-ITN) (FACETS-ITN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Hungary,France,Germany,Germany,Austria,Switzerland,France,Germany,Germany,France,Sweden,Germany
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-09-01
End date: 2013-08-31
Duration (months): 48.0
Total project cost (EUR): 4677779.0
EU funding (EUR): 4677779.0
Participants: 14
Project status: CLOSED

FACETS-ITN is a research and training network involving partners from 11 universities and research centres, 3 industrial companies and 1 semi-industrial research centre from 6 European countries. It combines competencies in neurobiology, computational neuroscience, information science, physics and electrical engineering. The scientific goal is to experimentally and theoretically explore the structure and the computational principles of biological neural circuits using in-vitro and in-vivo neurobiological experiments as well as analytical approaches, model building and simulation techniques. The concepts of learning and plasticity will be of particular importance. Based on the input from biology and modelling it is expected to prepare the grounds for novel hardware based computing devices that make use of such principles. Such devices will be built and operated in the form of large scale demonstrators as part of the research plan. Within the training network 21 selected Ph.D. students will be integrated into an existing international research environment and receive a strongly interdisciplinary training. The training comprises an intense exchange and visiting programme, specific training workshops for all scientific areas covered as well as in non-scientific key competencies.. This training concept will enhance their original academic education in order to cope with the challenges of this diverse international research environment. The proposed training programme will be closely coupled to existing research projects as well as graduate programmes of participating universities. It will create a sustained infrastructure based on web-based learning as well as on scientific interdisciplinary networks and the intersectional exchange with industry. The community building among Ph.D. students from different disciplines will include students from other projects, in particular the current FACETS integrated project and its planned successor.

Keywords: neurobiology,microelectronics,computational principles,neuromorphic hardware,plasticity,learning,computational neuroscience,spiking neural networks,hybrid networks,neuroinformatics
Multiscale Modeling of Chemical and Biochemical Systems (MULTIMOD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Greece,United Kingdom,Denmark,Germany,Belgium,United Kingdom,Italy,France,Austria,Germany
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-12-15
End date: 2013-12-14
Duration (months): 48.0
Total project cost (EUR): 4311643.0
EU funding (EUR): 4311643.0
Participants: 13
Project status: CLOSED

The MULTIMOD Training Network will have duration of 48 months and will bring together 8 academic research groups with 5 industrial partners from 8 European countries to undertake innovative research and scientific research training in “Multi-Scale Computational Modeling of Chemical and Biochemical Systems”. The network will provide unique cross- and multi-disciplinary training opportunities for 19 ESRs (each for 3 years) with background in chemistry, chemical engineering, physics, biology and applied mathematics. The MULTIMOD training network will address the objectives of a) equipping young researchers at the start of their careers with the knowledge and skills required for Europe&apos;s knowledge-based economy and society and b) overcoming the fragmentation that exists across the European chemical/biochemical research sector. MULTIMOD will intend to raise the efficiency of the chemical/biochemical research sector and improve Europe’s attractiveness for researchers by (a) concentrating on advances in process modeling and simulation and (b) offering decisive training and transfer of knowledge opportunities. The operation and scope of the training network will be in accordance with the objective identified in the SusChem report ‘Vision for 2025 and Beyond’ as ‘the urgent need to train the next generation of individuals able to work across the boundaries of chemistry, biology, chemical and biochemical engineering’.

Keywords: chemical engineering,process engineering,multiscale modeling,chemical/biochemical production systems
BrainTrain: Integrative neuroscience school on brain function and disease (BRAINTRAIN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,Japan,Italy,Germany,United Kingdom,Germany,France,Sweden,Belgium,Germany,Sweden
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-11-01
End date: 2013-10-31
Duration (months): 48.0
Total project cost (EUR): 3316876.0
EU funding (EUR): 3316876.0
Participants: 14
Project status: CLOSED

Brain disorders, in particular neurodegenerative diseases and mental illnesses are among the most prevalent and debilitating diseases. Because they are chronic, quality of life and socio-economic prospects are dramatically impaired. Increased life expectancy further enhances the impact of brain dysfunction on society. In coming decades this burden will grow into one of most pressing and costly problems of the EU. Prevalent brain disorders are typically caused by the interplay of environmental factors and genetic variation in multiple genes, which is currently being mapped by large international efforts. Future brain research should aim at integrative projects as a next step to characterize complex interplay between these multiple genetic and environmental factors to reveal how this translates into disease. To succeed, a new generation of neuroscientists is needed, capable of integrating information across different levels, from genes and proteins to synapses, and from networks up to complex brain (dys)function. Eight leading EU institutes (Amsterdam, London, Paris, Heidelberg, Stockholm, Magdeburg, Leuven and Trieste) together with the Japanese RIKEN, five commercial partners and FENS have formed BrainTrain ITN. Partners were selected on their outstanding publication records and ability to integrate different disciplines. BrainTrain builds on our knowledge of genome information and exploits innovative technologies and infrastructure to integrate this to unravel the (dys)function of living neurons, networks and the whole brain. Local specialists offer network-wide training and meetings. Our existing EU funded resources (IP EUsynapse, NeuroCypres and Neuromics EST) will provide an excellent, multicultural and inspiring environment for a new generation of integrative neuroscientists. BrainTrain will deliver 15 skilled ESR prepared for future challenges in neuroscience with optimal career opportunities and the ability to contribute to the fight against brain disorders.

Keywords: neurosciences,brain genetics,medical genetics,cellular neurobiology,neuronal circuits,behavior
Joint training and research on Hedhehog-Gli signalling and its pharmacological modulation for regenerative medicine (HEALING)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland,United Kingdom,Spain,Greece,Sweden,Austria,Italy,Germany
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-11-01
End date: 2013-10-31
Duration (months): 48.0
Total project cost (EUR): 3733564.0
EU funding (EUR): 3733564.0
Participants: 9
Project status: CLOSED

Debilitating degenerative diseases such as non-healing wounds and neurodegeneration do not yet have a cure. They represent a huge unmet medical need worldwide, especially in the aging European population. To reduce the incidence and improve recovery from such ephitelial diseases there is an major need to understand molecular signaling in order to promote stem cell behavior and enhance regeneration and healing. The key objectives of the HEALING network are 1) to train researchers in the fields of molecular signaling, developmental genetics, stem cell biology and small molecule chemistry; 2) to elucidate the mechanisms regulating one of the most promising pathways, Hedgehog-Gli (Hh-Gli) signaling; 3) to manipulate it by the development of specific small molecule agonists for future therapeutic use. Specifically, our research will (a) analyze the basic molecular mechanisms of Hh-Gli signaling in two model organisms and in human cells using leading technologies. In particular, (b) address the mechanisms that ensure controlled Hh-Gli function during skin wound healing and brain repair. (c) develop new small molecule Hh-Gli agonists for use as tools to be used as future therapeutics to enhance wound healing, regeneration and repair in a controlled manner. This network consists of 7 leading academic and research institutions, and 2 biotech companies from 8 European countries. It strengthens existing scientific collaboration, provides complementary expertise and brings together a critical mass for training and research. Additionally, it includes experts from Europe, Canada and Singapore, notably a pioneer in Hh-Gli signaling. HEALING will greatly enhance the training of the next generation of leading scientists in Hh-Gli signaling, stem cells and regenerative medicine. Thus, it will increase the competitiveness of highly skilled staff and of the European biotech industry, which has just recently discovered the role of Hh-Gli signaling in human disease and lags behind the US

Keywords: molecular mechanisms,hh-gli signaling,model organisms,regenerative mechanisms,ephitelial diseases,wound healing,cross-dosciplinary training,biotech,small molecule chemistry,brain,skin
Geometric phases, pumping, and dissipation in quantum devices (GEOMDISS)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Future and emerging technologies
Action type: Collaborative project
Countries involved: Germany,Italy,Finland,Israel,Switzerland,Hungary,France,Germany
Call:  (FP7-ICT-2009-C, 2009)
Start date: 2009-09-01
End date: 2013-02-28
Duration (months): 42.0
Total project cost (EUR): 2733693.0
EU funding (EUR): 2045034.0
Participants: 10
Project status: CLOSED

The aim of this project is to investigate how dissipation influences the geometric phases and geometric pumping in quantum solid-state devices and to assess the role of geometric manipulations in future ICT applications. Since all realistic solid-state devices suffer from dissipation due to their coupling to uncontrolled environment with many degrees of freedom it is crucial to understand how the geometric effects are modified and whether they are still useful.

Keywords: geometric phases,pumping,dissipation
Marie Curie Initial Training Network for the tailored supply-chain development of the mechanical and electrical properties of CNT-filled composites (CONTACT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,United Kingdom,Spain,Finland,Spain,Portugal,Hungary,Netherlands,Germany,Germany,Finland
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-10-01
End date: 2014-03-31
Duration (months): 54.0
Total project cost (EUR): 3477181.0
EU funding (EUR): 3477181.0
Participants: 12
Project status: CLOSED

The EU is currently directing intensive research efforts into nanotechnology. Carbon Nanotubes (CNTs), with the electrical conductivity of copper and an E-modulus 10 times greater than steel, are one of the most promising developments, enabling the creation of materials with revolutionary characteristics. The commercial potential is huge, but only a fraction of the possible applications have reached the market. Collaboration is needed between academia and industry, so that processes developed on a laboratory scale can be upscaled for industrial application. This consortium, which achieves an optimal balance between academia and industry (50:50) in the field of CNTs, and which spans the entire value added chain from CNT synthesis to implementation in saleable products, is convinced that the 576 person-months spent on this project will achieve this aim. 18 researchers, in unique collaboration with cutting-edge teams, will work to overcome recognised limitations in the state of the art, including the adjustment of CNT surface properties, CNT dispersion in thermosets and thermoplastics, reliable analysis and characterisation. Carefully structured networking will ensure the efficient exchange of knowledge between researchers, the partners and society. Focus on 3 specific end-use applications (construction, wind blades, electrodes) will ensure quantifiable and tangible results. The predicted growth of nanotechnology can only be sustained through the education of scientists. The vast teaching experience of the partners will ensure a high-quality training program. Through mentoring by world-class researchers, conferences, courses ranging from leadership for women to presentation skills, interdisciplinary and intersectoral experience, the appointed researchers will gain scientific know-how and the complementary skills necessary to exploit it. The S&T and training elements will combine to form a structured program, adaptable to each researcher's needs.

Keywords: nanotechnology,carbon nanotubes,industrial implementation
'Integrated Training Programme for Analysis, Assessment and Advice on EU External Action and its Institutional Architecture' (EXACT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Czechia,United Kingdom,Belgium,Netherlands,Finland,Italy,Hungary
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2010-01-01
End date: 2013-12-31
Duration (months): 48.0
Total project cost (EUR): 2625995.0
EU funding (EUR): 2625995.0
Participants: 10
Project status: CLOSED

The Initial Training Network “Integrated Training Programme for Analysis, Assessment and Advice on EU´s External Action and its Institutional Architecture” (EXACT) aims at preparing 12 Early Stage Researchers (ESR) for professional and academic careers in universities as well as in the public and private sector in academically based consulting for policy makers. The training network focuses its research on major current and future challenges of the EU in the fields of Commercial Policy, Common Foreign and Security Policy, Common European Defence Policy and Development Cooperation (e.g. EU crisis management in Georgia). The training provided through EXACT intends to bridge the gap between Ph.D. training within the academic world on the one hand and the “down-to-earth” need of potential employers in consulting or advisory circles on the other. Therefore, the project pursues an integrated two track curriculum that involves three universities and six think tanks: The scientific track concentrates on academic training leading to a Ph.D. degree, track II focuses on the training of professional skills. Given the growing market for academically trained EU experts in both public and private sectors, the integrated curriculum develops a triple “A” catalogue of skills: theory-led Analysis and Assessment of potential future scenarios in the field of EU’s external action and Advice for strategies. The early stage researchers will attend a 36 month training programme including local and network-wide activities (e.g. individual research projects and Network Seminars) provided by universities and think tanks in the network. The early stage researchers will be given the opportunity to obtain a double PhD degree („co-tutelle”) from two participating universities as well as the EXACT Certificate issued by all participating organisations.

Keywords: social sciences,integrated two track training programme in three phases on eu external action and its institutional architecture,universities and think tanks,ph.d.,exact certificate
Low-dimensional quantum magnets for thermal management (LOTHERM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,France,Cyprus,Netherlands,Greece,Slovenia,Germany,Switzerland,Germany
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-10-01
End date: 2013-09-30
Duration (months): 48.0
Total project cost (EUR): 2579032.11
EU funding (EUR): 2579032.11
Participants: 9
Project status: CLOSED

Thermal management in innovative technology is a major problem to be solved, especially in novel electronic devices, such as further miniaturized microchips, hard disks and interfaces between biological structures (e.g. nerve cells) and semiconductor microstructures. In this Initial Training Network (ITN) we will train young researchers through an experimental/technological and theoretical approach to the application of a new highly efficient magnetic mode of thermal conduction for thermal management. This magnetic heat transport was discovered by members of this consortium and occurs in novel quasi-one dimensional insulating oxides. The crucial point of this project is that around room temperature the magnetic heat conductivity (of the order 100 W/Km) is as efficient as metallic heat conduction. Moreover, compared to conventional materials with high thermal conductivity, these novel compounds offer essential advantages: a) They are electrically insulating, b) heat is conducted primarily along one direction and c) heat is carried by localized spins which could allow for tunable heat conductivity at room temperature by manipulation of the spins with magnetic fields or light. Our scientific goal of exploiting this novel mode of heat transport for thermal management will be the basis for the research training in this ITN, which consists of 7 academic and 2 level-1 industrial partners. In order to tackle this scientific challenge in an multidisciplinary approach (physics, chemistry, materials science, computational science, electronic media), the fellows in our ITN will be trained on cutting edge experimental and theoretical techniques. In addition to training-through-research, the fellows will receive individual and collective training measures covering both scientific and complementary skills. We are especially dedicated to applying state-of-the-art training through electronic media which will reinforce the effectiveness and availability of training within this ITN.

Keywords: physical sciences,applied physics,solid state physics,mechanical and thermal properties