Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Hierarchical Analysis of Complex Dynamical Systems (HIERATIC)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Future and Emerging Technologies
Action type: Collaborative project
Countries involved: United Kingdom,Sweden,United Kingdom,Germany
Call:  (FP7-ICT-2011-8, 2011)
Start date: 2012-10-01
End date: 2016-04-30
Duration (months): 43.0
Total project cost (EUR): 2429435.0
EU funding (EUR): 1899967.0
Participants: 4
Project status: CLOSED

The central aim of HIERATIC is to develop a new framework for understanding complex systems as a multi-level hierarchy of sub-systems using non-linear decompositions. To achieve this goal, HIERATIC is structured in three interlinked sets of activities: theoretical work, deriving the novel mathematics required to identify suitable non-linear state space reductions of complex systems; software development of efficient multi-scale simulation and prediction libraries; demonstrators, illustrating the power of our results – network dynamics, cell cycle simulations, social interactions in animals. The theoretical work will use unconventional approaches from topology and dynamical systems theory to derive an algorithmic approach to identifying “coarse-grainings” of large complex systems. These algorithms will be used to develop highly efficient simulation and prediction tools, integrated with the world-leading software libraries MASON and PRISM. The demonstrators will show the potential application of these techniques, in a range of applications, including validation on large empirical data sets. The project brings together leading researchers in complex systems theory, biosystems, multi-agent simulation, and experimental ecology, from around the EU and USA.

Keywords: hierarchies,dynamical systems,topology,simulation,network dynamics,biochemical reactions,social behaviour
Initial Training Network for Neurogical disorders orchestrated by cytoKines (NEUROKINE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Switzerland,France,Austria,Italy,Israel,Netherlands,Germany,Germany,United Kingdom,Germany
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2017-05-31
Duration (months): 53.0
Total project cost (EUR): 3536795.62
EU funding (EUR): 3536795.62
Participants: 13
Project status: CLOSED

Neuroinflammatory disease, in particular multiple sclerosis affects more than 700.000 people within Europe alone. European countries are at the forefront of neuroimmunological research and students in medicine and biology are greatly attracted by the field. Neuroimmunology research further impacts our understanding of the ethiopathology of other CNS-disorders including Alzheimer’s Dementia and Morbus Parkinson. The ability of inflammatory immune cells to cause tissue damage within the nervous system is largely governed by soluble mediators including cytokines/chemokines, cytolytic molecules and growth factors. The therapeutic targeting of such mediators has proven successful for the treatment of a number of inflammatory diseases, yet is failing for the treatment of neuroinflammatory disorders. Clearly, the rules and regulatory elements, which govern inflammation and tissue injury within the CNS, differ significantly from those of other tissues and a unique CNS-focused research approach to unravel these rules is required. In this ITN proposal, we will train ESRs and ERs specifically in Neuroimmunology by combining prominent laboratories in academia and industry on the task to study the communication networks between immune and CNS-resident cells. Scientifically, we focus particularly on the soluble factors mediating cell-cell communication at the immune-CNS interface. To this end, we combine expertise in molecular and cellular Neuroimmunology with Neuropathology of human and animal models of CNS inflammation. In addition, our goal is to further utilize inflammatory processes for neuroprotection.

Keywords: central nervous system,inflammation,multiple sclerosis,alzheimer's disease,cns trauma,autoimmunity
Peroxisomes: key to cell performance and health (PERFUME)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,Netherlands,United Kingdom,Norway,Germany,Germany,Germany,Germany,Spain,Sweden,Germany
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 3911064.03
EU funding (EUR): 3911064.03
Participants: 12
Project status: CLOSED

The PERFUME (PERoxisome Formation, Function, MEtabolism) program is an interdisciplinary and intersectoral ITN providing state-of-the-art research training at the interface of medicine, plant and fungal biology. The PERFUME S&T specifically aims at unraveling the principles of peroxisome biology. Peroxisomes have been discovered relatively recently (in 1954). Consequently, the level of understanding of their biology is relatively weak compared to the knowledge of other organelles. Despite their modest appearance, they are crucially important for cell vitality. Peroxisomes ubiquitously occur in eukaryotes, display an unprecedented versatility of functions and are essential in man. Recent findings indicate that improper functioning of peroxisomes contributes to ageing and age-related diseases. However, there are still major gaps in our current knowledge of peroxisome biology. PERFUME aims to fill these gaps by focusing on i) the identification of novel peroxisome functions, ii) in-depth understanding of the compartmentalization of functions in peroxisomes and iii) unraveling the principles of peroxisome proliferation. Enhancing knowledge on these three themes is relevant for medicine, agriculture and biotechnology and demands directed analyses, which require the combined expertise from different disciplines and sectors that cut across historically separated fields. PERFUME brings together such a team comprising of top scientists from the fields of cell biology, biochemistry, genomics, proteomics, metabolomics, mathematical modeling, bioinformatics and protein structure analysis. Together, PERFUME shows maximal complementarity and synergy to warrant optimal training facilities for the participating students.

Keywords: peroxisomes,disease,biotechnology,proteomics,protein structure,systems biology,modeling,molecular biology,microscopy,fungi,plant,mammals,organelle biogenesis and homeostasis
COgnitive RAdio for SATellite Communications (CORASAT)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Pervasive and Trusted Network and Service Infrastructures
Action type: Collaborative project
Countries involved: Italy,France,Luxembourg,United Kingdom,Belgium
Call:  (FP7-ICT-2011-8, 2011)
Start date: 2012-10-01
End date: 2015-09-30
Duration (months): 36.0
Total project cost (EUR): 4055372.0
EU funding (EUR): 2479742.0
Participants: 6
Project status: CLOSED

The CoRaSat project aims at investigating, developing, and demonstrating cognitive radio techniques in satellite communication systems for spectrum sharing. Outcomes of the study will drive the definition of strategic roadmaps to be followed by industry stakeholders, European Institutions, and Governmental actors towards regulatory and standardization groups in order to ensure that the necessary actions are undertaken to open new business perspectives for SatCom through cognitive radio communications in support of the Digital Agenda for Europe. Flexible spectrum utilization is a surging trend for the optimized exploitation of spectrum resources, and the cognitive approach has already demonstrated its potential for terrestrial systems, but not yet in the SatCom domain. However, SatCom are fundamental to achieve the challenging objectives of fast broadband access for everyone by 2020: their inherent large coverage footprint makes them the most suitable access scheme to reach those areas where deployment of wired and wireless networks is not economically viable. CoRaSat puts together these two elements by considering Cognitive Radio approaches for coexistence scenarios in spectrum allocated to any SatCom service. For the first time in SatCom research initiatives, CoRaSat will systematically and thoroughly approach the Cognitive Radio concept considering SatCom peculiarities and characteristics. CoRaSat will identify scenarios and use cases, focusing on broadband applications and considering other services, like interactive broadcasting, narrowband applications, etc., where cognitive radio can improve spectrum exploitation. Technology enablers for the identified scenarios will be developed and demonstrated for specific use cases through analysis, simulation, and testbed implementations. Flexible spectrum usage has potential benefits for SatCom as well as threats; CoRaSat aims at demonstrating that the benefits outnumber the threats and open up new business perspectives

Keywords: satellite communications systems,broadband access,flexible spectrum utilization,cognitive radio
Training Program for the Design of Resource and Energy Efficient Products by High Pressure Processes (DOHIP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Hungary,Austria,Slovenia,Spain,Germany
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-02-01
End date: 2017-01-31
Duration (months): 48.0
Total project cost (EUR): 2970954.0
EU funding (EUR): 2970954.0
Participants: 7
Project status: CLOSED

Aim of the Training Program (DoHip) is to meet the growing demand of Europe’s industry for highly trained scientists and engineers in process technology. Process Technology is fundamental for chemical, pharmaceutical, and polymer industry as well as food industry and cosmetics. High Pressure Processes like the Polyethylene Synthesis have been developed in Europe, leading to the outstanding position of European industries. Today’s demand on industry is to develop sustainable products and processes. High Pressure Technology can provide the answer. In the training network knowledge on the unique possibilities of high pressure is generated. New technologies and biobased products like leather from pressure supported tanning, free of waste water containing chromium, are developed and demonstrated in science and industry. For designing new, innovative and sustainable products and processes interdisciplinary project teams will work hand in hand. This is reflected in the consortium, comprising chemical and mechanical engineers as well as natural scientists. Five leading European universities with proven records in high pressure technology (Bochum, Budapest, Graz, Maribor and Valladolid) together with one Fraunhofer institute and one SME are forming the core of DoHip. They are supported by 8 companies from 7 European countries ranging from SMEs to global players. Each partner has complementary expertise and equipment which will be combined, resulting in a unique training program. Besides the highly sophisticated training through research in high pressure technology training on complementary skills (e.g. IP, presentation skills, project management, entrepreneurship, scientific writing) will be provided. Each ESR will absolve an internship at an associated industrial partner to improve job opportunities. Researchers educated in former RTN programs are taking over mentorship for the DoHip ESRs, introducing them into the existing high pressure network across Europe.

Keywords: g302 chemical engineering - technical chemistry,g316 production technology - process engineering,p218 phase transitions - phase equilibria,high pressure technology,supercritcal fluids
MARie CuRIe AGEing Network (MARRIAGE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,Netherlands,Germany,Denmark,Greece,Germany,United Kingdom,Germany,Switzerland,Germany
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2016-09-30
Duration (months): 48.0
Total project cost (EUR): 3955362.86
EU funding (EUR): 3955362.86
Participants: 11
Project status: CLOSED

One of achievements of developed societies has been the remarkable extension of human lifespan. In the upcoming decades the number of Europeans with advanced age will increase dramatically. It is evident that age-associated diseases will become much more prevalent. This poses challenges for society but also opportunities for commercial enterprises that develop strategies to combat deleterious consequences of ageing. However, our understanding of the mechanisms that contribute to ageing and its associated pathologies remain superficial and therapeutic or nutritional interventions unexplored. The complex nature of ageing as a scientific field calls for a multidisciplinary approach where teams of academic and industrial researchers join forces. The objective of this Network is to provide training in the biology of ageing to 11 Early Stage and 4 Experienced Researchers. We have assembled a premier group of scientists that focus their activities on the molecular mechanisms that underlie ageing, with an emphasis on how maintenance of genomic integrity in self-renewing tissues is preserved under different metabolic rates. The key aim of this training program is the elucidation of the molecular pathway by which intrinsic genomic integrity can be modified by the extrinsic rate of metabolism. Our Network consists of 10 full and 2 associated partners, representing 7 Member states and Switzerland and Canada, and include 4 commercial enterprises. Multiple complementary training schemes have been implemented in the Network. These include specific research projects (including multiple academic and industrial secondments), a variety of dedicated courses organized by the academic partners of the Network, and finally, training organized by the industrial partners of the Network. Trainees will become experts in the multidisciplinary field of ageing, and are expected to constitute future leaders in the field of ageing science and shape commercial activities in this realm.

Keywords: health sciences,ageing,stem cells,dna repair,genome stability,metabolism
Epigenetic regulation of economically important plant traits (EPITRAITS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,Germany,Netherlands,Spain,Germany,United Kingdom,France,Belgium,Poland,Germany
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2016-09-30
Duration (months): 48.0
Total project cost (EUR): 3587946.12
EU funding (EUR): 3587946.12
Participants: 13
Project status: CLOSED

The mission of EpiTRAITS is to train young researchers in epigenetic gene regulation and flowering in the model plant Arabidopsis thaliana and the crop plants maize (Zea mays) and barley (Hordeum vulgare). Epigenetic gene regulation confers stability of gene expression patterns through cell divisions while allowing changes in expression in response to environmental or developmental cues. Although changes in epigenetic gene regulation are a major cause for trait variation, no rational strategies have been developed that utilize this knowledge for crop breeding purposes. EpiTRAITS will focus on one of the key plant traits, flowering, which is controlled by various epigenetic mechanisms. The scientific program aims to bridge the gap between fundamental and applied research by translating results from epigenetic research in model organisms to improved technologies for crop breeding and molecular diagnostic tools.

Keywords: genome-wide profiling,field crops,computational biology,plant biotechnology,epigenetics,plant development,kit development,bioinformatics,gene regulation,flowering time,chip-seq,commercialization
Multi-disciplinary training environment for next generation hydrogel-based smart bio-interactive materials (NEOGEL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ireland,Netherlands
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-11-01
End date: 2016-10-31
Duration (months): 48.0
Total project cost (EUR): 993418.14
EU funding (EUR): 993418.14
Participants: 2
Project status: CLOSED

Smart resorbable hydrogels will play a key role in next-generation biomedicine, for instance as platform materials for tissue engineering. As these materials have potential to address a wide range of medical conditions, significant growth for the biomedical materials industry is forecast. To explore this opportunity and exploit the potential, highly-qualified and well-trained biomaterials experts are urgently required. NeoGel will address this need by providing cross-disciplinary training to four ESRs in an exciting academia-industry collaboration focused on novel hydrogels. In this EID, two leading academic and industrial groups in polymer and biomaterial science, complemented by associate partners in pharmacology and tissue engineering, will apply an integrated approach to the development of new biomaterials. This will comprise iterative improvement of commercial and of novel-hydrogels, providing the ESRs with an ideal, rapidly developing, environment in which to learn. The training environment will be supported by structured training in transferable skills, covering entrepreneurship, project management and communication, delivered by private sector and university specialists. In a unique approach NeoGel will link up with another Marie Curie ITN and with an Irish structured PhD programme, for training in biotherapeutics. The training provided will match the anticipated skills required by the next generation of research leaders in the biomaterials/regenerative medicine industry. The ESRs will emerge with excellent scientific skills and with intuitive understanding of the needs of industry and of conducting industrial projects. They will have rapidly matured through the programme and will graduate fully able to operate in commercialised research environments. Hence they will make a significant contribution to the expansion of the European biomaterials industry, and to the development of the next generation of biomaterials for improving quality-of-life worldwide.

Keywords: biomaterials,hydrogel,polymers,scaffolds,material,bioengineering,drug-delivery,polypeptides,medical coatings
Simulation of fire technical properties of products and construction barriers to support efficient product development in industry (FIRE TOOLS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark,Sweden
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 1465278.12
EU funding (EUR): 1465278.12
Participants: 2
Project status: CLOSED

The current fire testing and classification systems based on prescriptive building codes have severe limitations, restricting innovation and cost-efficiency in companies supplying materials/components for buildings and in the construction sector in general. This is creating a growing need for more flexible performance-based fire engineering, and calls for the development of appropriate methods/tools to support that change. Despite scattered efforts in Academia and Industry for progress in the area of fire properties simulation, there is a strong lack of appropriately trained human resources to push the research base in the field further and building the proper environment for shifting paradigms in technological as well as regulatory terms. The FIRE TOOLS consortium comprises the Danish Institute of Fire and Security Technology (DBI) and the Department of Fire Safety Engineering and Systems Safety from Lund University (ULUND) in Sweden as level 1 participants, and nine Associated Partners (1 university and 8 private companies, namely 4 SMEs). It aims at providing a training network for five Early-Stage Researcher (ESRs) which will carry out research with focus on creating computing simulation methodologies, tools and models to increase the usability of fire tests conducted on building products and constructions (i.e. real fire tests in laboratory or pilot facilities) by fire properties simulations. More specifically, they will address the determination of the fire properties of building products, content and barriers, in order to assist companies, based on advanced computational models and predictions, to simulate and predict the fire performance of materials, products and structures earlier in their product development processes. The successful implementation of FIRE TOOLS will benefit DBI when providing fire testing services, as well as manufacturers and suppliers of materials/components to buildings, and support innovation in the construction industry in general.

Keywords: fire safety and engineering,fire simulation,fire technical properties,computer modelling,construction materials,building products,content and barriers