Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Digitalized Clone for Personalized Medicine (DCPM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Belgium,Hungary,Hungary,New Zealand,Hungary,Hungary
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2019, 2019)
Start date: 2020-01-01
End date: 2025-10-31
Duration (months): 70.0
Total project cost (EUR): 864800.0
EU funding (EUR): 680800.0
Participants: 10
Project status: SIGNED

Background: Health consumes ~10% of GDP in the OECD, and grows an unsustainable 7-11% per year, and is ~1% of GDP for intensive care alone, driven by chronic diseases and aging populations. Limited funding leads to an ‘equity gap’ in health funding, where more people go untreated, less treated (rationing), and/or rely on private insurance and care, creating and exacerbating inequality. Problem: This labor intensive sector has not made productivity gains, and increasing demographic demand for intensive care is multiplied by a growing need for personalized, precision solutions to care. Challenge: Reverse this trend by linking engineering, medicine, and industry to improve the quality, precision and productivity of intensive care, and create a template for other areas of care. Objectives: Use model-based methods and novel system identification technologies to create validated virtual patient models for use in personalizing care to enhance its quality and productivity. Proposed Solution: Tight collaboration between engineering research, clinical medicine, and industry to create, validate, and implement precision, intensive care medicine (DCPM) using in-silico virtual patients. The proposal authors are world-leaders in creating highly validated virtual patients, and translating them to clinical use to provide precision, next-generation productive, intensive care solutions. It will merge model-based methods in metabolic, cardiovascular and pulmonary systems – 3 leading causes of intensive care admission, mortality and cost - to create individual (and then combined) virtual intensive care patients to personalize care at the bedside. The consortia leverages significant research funding in 3rd country partners for model-based medical solutions. This proposed mobility optimizes this research for maximum social and economic impact in the EU and NZ – Doing medicine better via inter-disciplinary, in-silico solutions to productivity in intensive care.

Keywords: intensive care,personalised medicine,virtual physiological human,physiological model integration,diagnostic and decision support
SHale gas Exploration and Exploitation induced Risks (SHEER)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Poland,United States,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: Understanding, preventing and mitigating the potential environmental impacts and risks of shale gas exploration and exploitation (H2020-LCE-2014-1, 2014)
Start date: 2015-05-01
End date: 2018-04-30
Duration (months): 36.0
Total project cost (EUR): 2680470.0
EU funding (EUR): 2601720.0
Participants: 9
Project status: CLOSED

The objective of SHEER is to develop best practices for assessing and mitigating the environmental footprint of shale gas exploration and exploitation. The consortium includes partners from Italy, United Kingdom, Poland, Germany, the Netherlands, USA. It will develop a probabilistic procedure for assessing short and long-term risks associated with groundwater contamination, air pollution and induced seismicity. The severity of each of these depends strongly on the unexpected enhanced permeability pattern, which may develop as an unwanted by-product of the fracking processes and may become pathway for gas and fluid migration towards underground water reservoirs or the surface. An important part of SHEER will be devoted to monitor and understand how far this enhanced permeability pattern will develop both in space and time. These hazard may be at least partially inter-related as they all depend on this enhanced permeability pattern. Therefore they will be approached from a multi-hazard, multi parameter perspective. SHEER will develop methodologies and procedures to track and model fracture evolution around shale gas exploitation sites and a robust statistically based, multi-parameter methodology to assess environmental impacts and risks across the operational lifecycle of shale gas. The developed methodologies will be applied and tested on a comprehensive database consisting of seismicity, changes of the quality of ground-waters and air, ground deformations, and operational data collected from past case studies. They will be improved by the high quality data SHEER will collect monitoring micro-seismicity, air and groundwater quality and ground deformation in a planned hydraulic fracturing to be carried out by the Polish Oil and Gas Company in Pomerania. Best practices to be applied in Europe to monitor and minimize any environmental impacts will be worked out with the involvement of an advisory group including governmental decisional bodies and private industries.

Keywords: shale gas,environmental impact
SHARED GREEN DEAL: Social sciences & Humanities for Achieving a Responsible, Equitable and Desirable GREEN DEAL (SHARED GREEN DEAL)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Research and Innovation actions
Countries involved: Germany,Austria,Austria,Ireland,Germany,Spain,Cyprus,Greece,Slovenia,Hungary,Belgium,France,France,France,Czechia,Netherlands,Netherlands,Denmark,Portugal,United Kingdom,United Kingdom
Call: Behavioural, social and cultural change for the Green Deal (H2020-LC-GD-2020-4, 2020)
Start date: 2022-02-01
End date: 2027-01-31
Duration (months): 60.0
Total project cost (EUR): 4996098.75
EU funding (EUR): 4996098.75
Participants: 22
Project status: SIGNED

The Social sciences & Humanities for Achieving a Responsible, Equitable and Desirable GREEN DEAL (SHARED GREEN DEAL) project brings together 22 leading organisations from across the EU including 8 universities, 3 research institutions, 8 network organisations and 3 SMEs. Our network partners cover core elements of the European Green Deal cross cutting priorities such as civil society, democracy, gender, energy, environment, circular economy and innovation. Our objectives directly address the call challenge with an aim to share actions, understandings, evidence, insights, responsibilities and benefits across stakeholders including policymakers and civil society. Issues of inclusivity and diversity are at the heart of the project to particularly account for disadvantaged and vulnerable social groups. SHARED GREEN DEAL will meet its objectives through a set of 11 workpackages. It is structured around lessons from a set of 6 social experiments around 6 priority Green Deal topics. Each social experiment will be delivered across 4 member states. Importantly we take a transdisciplinary approach, covering 19 social science and humanities disciplines, with multi-stakeholder, practice-based and policy-science expertise, including gender studies as a key component throughout. The output includes the development of tools (e.g. an online Green Deal policy tracker), as well as translating project findings into stakeholder-specific policy briefs and roundtable events. The partners are committed to continuing to host the transnational network set up post-project to ensure longevity and impact beyond the life of the project. SHARED GREEN DEAL is expected to deliver changes in societal practices and in the behaviour of individuals, communities, and public and private organisations. Through the development of effective new strategies, we will address behavioural change and long-term commitment, trust, social acceptance and buy-in from people, communities and organisations.

Keywords: just transitions,gender,climate action,renewables,circular economy,energy efficiency,mobility,food,biodiversity,zero pollution
Joint European Canadian Chinese development of Small Modular Reactor Technology (ECC-SMART)

Framework: Horizon 2020 — Euratom
Programme: Nuclear fission and radiation protection
Theme: Nuclear safety
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Spain,Ukraine,Hungary,Slovakia,Sweden,China,Romania,Belgium,Finland,Slovenia,Czechia,Czechia,United Kingdom,United Kingdom,Canada
Call: Support for safety research of Small Modular Reactors (NFRP-2019-2020, 2019)
Start date: 2020-09-01
End date: 2025-02-28
Duration (months): 54.0
Total project cost (EUR): 8971950.0
EU funding (EUR): 3997237.5
Participants: 20
Project status: SIGNED

The ECC-SMART is oriented towards assessing the feasibility and identification of safety features of an intrinsically and passively safe small modular reactor cooled by supercritical water (SCW-SMR), taking into account specific knowledge gaps related to the future licensing process and implementation of this technology. The main objectives of the project are to define the design requirements for the future SCW-SMR technology, to develop the pre-licensing study and guidelines for the demonstration of the safety in the further development stages of the SCW-SMR concept including the methodologies and tools to be used and to identify the key obstacles for the future SMR licencing and propose a strategy for this process. To reach these objectives, specific technical knowledge gaps were defined and will be assessed to achieve the future smooth licensing and implementation of the SCW-SMR technology (especially the behaviour of materials in the SCW environment and irradiation, validation of the codes and design of the reactor core will be developed, evaluated by simulations and experimentally validated). The ECC-SMART project consortium consists of EU, Canadian and Chinese partners to use the trans-continental synergy and knowledge developed separately by each partner. The project consortium and project scope were created according to the joint research activities under the International Atomic Energy Agency, Generation-IV International Forum umbrella and as much data as possible will be taken from the already performed projects. This project brings together the best scientific teams working in the field of SCWR using the best facilities and methods worldwide, to fulfil the common vision of building an SCW-SMR in the near future.

Keywords: small modular reactor,supercritical water,licensing,methodologies,material testing,thermal hydraulics,neutronics,pre licensing studies,sythesis of guidelines,international scientific synergy
The dynamics of the mammalian epigenome during transcription factor-induced cell fate conversion (3Dconvert)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-01
End date: 2017-04-30
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

Cell fate conversion processes bear considerable therapeutic potential yet are poorly understood, and have thus remained slow, inefficient and difficult to translate into medical applications. The low conversion frequency in current systems, such as classic reprogramming to ‘induced’ pluripotent stem (iPS) cells, has precluded a molecular study of the critical early conversion events. We propose an interdisciplinary, exhaustive and unbiased approach to unravel the molecular events that accompany cell fate conversion processes, in particular during the early phase, using two uniquely efficient and controllable experimental systems. Special emphasis will be put on documenting the dynamics of three-dimensional genome topology, as this potential epigenetic conversion barrier has not yet been systemically characterized during cell fate conversions. We will apply genome-wide chromosome conformation capture and other genomic technologies on B cells undergoing nearly 100% efficient transdifferentiation into macrophages or reprogramming into iPS cells. In-depth computational analyses and dataset integration will reveal the dynamic relationships between transcription factor binding, key epigenetic regulatory mechanisms including genome topology, and the gene expression changes that ultimately lead to the implementation of a new cellular phenotype. Acquiring such insights will signify a breakthrough in our understanding of the epigenetic features that underpin cell identity and plasticity. Besides significantly advancing the state-of-the-art, the proposed action will maximize the applicant’s capacity of reaching professional maturity and scientific independence.

Keywords: transdifferentiation,reprogramming,gene regulation,epigenetics,genomics
Integral Security Trust Element for the Internet of Things (INSTET)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Netherlands
Call: Engaging SMEs in security research and development (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-10-01
End date: 2017-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Intrinsic-ID is a Dutch SME, spin-off from Philips Research, and a world leader in security solutions for chips, with 25+ patents. Intrinsic-ID has created a technology to uniquely identify and authenticate chips based on the inherent characteristics of their memory component (SRAM). This technology, a digital equivalent of a fingerprint, is called Physical Unclonable Function (PUF). Intrinsic-ID is working on INSTET – a fully-fledged security solution on top of PUF that will protect low-end chips that are omnipresent in IoT devices everywhere by making them physically and cryptographically secure and extremely resilient to advanced attacks. INSTET will work as a Root of Trust, i.e. a set of core software components that are always trusted by the chip, and provide a trust foundation for the IoT device and distributed IoT systems. INSTET addresses the core problem of semiconductor vendors and OEMs: lack of security. INSTET can be deployed on almost any chip, including the ones that are already in the field, without costly redesigns or additional hardware, generating savings of up to 35% per chip. In this 6-month feasibility study, Intrinsic-ID will investigate the product/market fit and business model fit in three most promising vertical segments of the semiconductor industry (wearables, medical electronics and automotive), develop a go-to-market strategy and calculate costs of scaling up.

Keywords: chipset,security,physical unclonable function,root of trust
Fighting Violence Against Women: The Credibility of European and Global Expert Bodies (VAW-Experts)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-04-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

Violence against women is a widespread phenomenon. The task of monitoring EU states’ compliance with their commitments in this field is largely dependent on a set of expert Treaty Bodies within the UN and the Council of Europe, which issue recommendations to states on how to improve their performance. Since these recommendations cannot be legally enforced, scholars posit that Treaty Bodies need to be credible in the eyes of states in order to generate effects. Yet, the extent to which these bodies’ credibility leads to the implementation of recommendations remains underexplored. This project assesses the credibility of UN and Council of Europe Treaty Bodies engaged in fighting violence against women, and tests the extent to which their credibility influences states’ implementation of recommendations. This assessment is necessary in view of improving the functioning of these bodies, stimulating states’ compliance with provisions protecting women from violence and thus, ultimately, ensuring the fulfillment of women’s rights. Data sources will be official documents and 50 interviews with UN, Council of Europe, and state officials involved in these mechanisms. Results will shed light on these instruments’ effectiveness, highlighting possible areas for improvement. I will perform this research at the School of Social and Political Science (SSPS) of the University of Edinburgh under the guidance of Prof. Christina Boswell, a world-leading political scientist. Conducting this project will strengthen my academic profile, preparing me for the tenure-track market and for obtaining advanced funding, which will allow me to establish my own research group. SSPS will strongly benefit from my stay in three ways, as I will: 1) share my knowledge and provide feedback to colleagues; 2) establish new collaborations between Edinburgh and other academic and non-academic institutes; 3) share my experience with acquiring postdoctoral funding with Edinburgh’s early-career researchers.

Keywords: global governance,human rights,knowledge and governance,united nations,council of europe
EmPowering electricity access in off-grid areas with a portable battery pack with Internet of Things connectivity (EmPower)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Denmark
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-09-01
End date: 2020-01-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Globally, about 1.2 billion households have no access to electrical energy. Despite the lacking access to electricity, many households placed in rural off-grid areas, in e.g. Africa, possess mobile technology, e.g. smartphones, and thus have access to the Global System for Mobile communication (GSM). PP-Power has developed an innovative and portable battery pack with Internet of Things connectivity targeting these many householders living without public electricity supply, but with access to GSM communication - Peoples Portable Power Pack (4P). Our solution is based on a state-of-the-art reusable lithium ion battery embedded with our proprietary electronics and cloud-based software to enable a Pay-As-You-Go payment model, as well as secure and remote battery monitoring and control, usage data collection, and software updates. The battery pack is charged from community owned solar PV installations, offering a unique combination of quality, affordability and scalability to meet the end-user’s gradually increasing electricity demand. These benefits are complemented by a unique flexibility in terms of business models and open connection of external equipment. Hence, our solution has the potential to give individuals in rural and small communities the opportunity of growth and education, as well as a healthier and more sustainable way of life than they have today. We have already tested our solution with local end-users proving the high value of our business concept. With the current project, we aim to accelerate the maturation of our solution for broader and faster introduction in the off-grid electricity market with an initial focus on Kenya and Tanzania as our launch markets. The project will contribute to place PP-Power in a competitive position within the market and assist Europe in the implementation of the UN Sustainable Development Goals.

Keywords: social innovation,cloud based software,pay as you go model,solar pv,sustainable development goals
Disinfecting the Stethoscope membrane through a hi-tech UV device (STET CLEAN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-08-01
End date: 2019-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

STET CLEAN® is a revolutionary high-tech ultraviolet (UV) device for stethoscope disinfection invented, designed and created by egoHEALTH, an Italian SME specialised in the development, engineering and production of hardware/software devices and innovative services in the field of bioengineering and biomedical information technology. STET CLEAN is safe for health professionals and patients alike, eco-friendly, suitable for all standard stethoscopes, with a pocket-sized body that can be worn on medical coats and easy-to-use (simply insert the stethoscope in the STET CLEAN device - when the indicator light turns off it is disinfected). The device is currently at TRL7 (technology readiness level 7), as the system has already been demonstrated in an operational environment. A first batch of prototypes (the basic version) were tested on the market to collect feedback from potential users. This feedback was then included in a second version: five thousand devices have been produced so far, but the selling price (approximately 150€) is not competitive yet! Therefore, we are asking for support from the SME phase 1 instrument to: ▪ Streamline production and evaluate STET CLEAN‘s scalability, with the aim of reducing production/final costs; ▪ Analyse the target markets, the needs of user groups and the regulations in each target country to adapt the system to national policies and customer requirements; ▪ Investigate market risks and establish corresponding mitigation strategies. ▪ STET CLEAN videos are available.

Keywords: hospital acquired infection,prevention,risk management,disinfection,ultraviolet c light,environmental friendly approach,automatic,safe,wearable device