Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
NetworkNature - Advancing nature-based solutions together (NetworkNature)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Protection of the environment, sustainable management of natural resources, water , biodiversity and ecosystems
Action type: Coordination and support actions
Countries involved: Germany,Germany,Belgium,Switzerland,France,Netherlands
Call: Multi-stakeholder dialogue platform to promote nature-based solutions to societal challenges: follow-up project (H2020-SC5-2019-3, 2019)
Start date: 2020-06-01
End date: 2023-07-31
Duration (months): 38.0
Total project cost (EUR): 2189833.75
EU funding (EUR): 2189833.75
Participants: 6
Project status: SIGNED

NetworkNature will establish a European and global platform allowing all interested stakeholders to access and contribute cutting-edge, innovative knowledge and expertise on nature-based solutions (NBS). Our consortium represents all relevant stakeholder groups and has access to a range of related networks. We have a strong track record and extensive expertise on this topic in terms of engagement, content, technical know-how and involvement in relevant policy processes at European Union (EU) and global level. This allows us to maximise the EU’s potential to become a global leader in deploying innovative NBS to address societal challenges, building on the ongoing work of all Horizon 2020 and BiodivERsA-funded NBS projects as well as relevant other initiatives and programmes in Europe and beyond. The project’s legacy will be ensured through establishing a sustainable platform structure that responds to the needs of the NBS community of innovators based on a sound and stable business model; providing support to and strengthening the NBS community, particularly small and medium enterprises, practitioners and policy-makers, to foster market uptake as well as the transfer and application of innovative NBS; by providing targeted dialogue opportunities across Europe and in regions, guidance and capacity building as well as using advocacy as vehicle to nurture NBS through policy, research and practice, particularly for design and standardisation; and, finally, by building on existing global initiatives to continue enhancing international cooperation to upscale the implementation of NBS. NetworkNature will help transform the EU’s vision of becoming a leader for NBS into reality through a comprehensive, up-to-date, open, user-oriented platform for NBS, building on the dynamic, but to date less streamlined development across the involved stakeholders, projects, existing platforms and policies in the EU over the past years.

Keywords: innovative nature based solutions,expertise sharing,dialogues
Injectable hydrogels for magnetically-activated, remote-controlled drug delivery (INMARE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,United States
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-22
End date: 2022-01-21
Duration (months): 36.0
Total project cost (EUR): 239191.2
EU funding (EUR): 239191.2
Participants: 2
Project status: CLOSED

The key goals of the INMARE project are: a) the training of a talented and experienced researcher, Dr Eneko Axpe, in the science, technology and industrial application of magnetic nanomaterials and drug delivery systems. The host and partners have critical knowledge and expertise in these fast growing fields. And b) the design, fabrication and (further) development of a minimally invasive, externally triggered, on demand drug delivery system. This interdisciplinary training program includes fabrication and full characterization of injectable nanocomposites, development of physical models of the drug diffusion in hydrogels, and application of AC magnetic fields for drug delivery. Such a program will support the talented researcher, who has already gained expertise in the area of nanomaterials for biomedical applications during his postgraduate career, in his endeavour to increase his exposure to both academic and industrial collaborations. To further his career in biomaterials, Dr Eneko Axpe envisions pursuing an extensive study of smart materials and their in vivo applications, fields which the partner at Stanford University and the host group at UPV/EHU have a world-recognized expertise in. Additionally, through a secondment at AstraZeneca, his industrial co-partner, he will receive further training in pharmacokinetics and the commercial applications of health products. The applications of this project are vast, ranging from medical treatments of chronic diseases such as cancer, to a basic understanding of the physics behind drug diffusion, which attest to its interdisciplinarity and high impact. Moreover, it will provide Dr Eneko Axpe with the opportunity to increase his supervision and teaching experience, gain project and intellectual property management expertise, research funding and proposal writing skills. Multidisciplinary activities will assist the experienced researcher in acquiring necessary competences and reaching professional maturity.

Keywords: drug delivery systems,injectable hydrogels,nanomaterials,magnetic materials
Tools to Carve out Conformal Field Theories (TcCFT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Belgium,United States
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-25
End date: 2020-09-24
Duration (months): 36.0
Total project cost (EUR): 240530.4
EU funding (EUR): 240530.4
Participants: 2
Project status: CLOSED

Recently a number of research efforts have been dedicated to the conformal bootstrap. The basic principle is that conformal symmetry and quantum mechanics should suffice to fix uniquely the dynamics of Conformal Field Theories (CFTs), which lie at the fixed points of the renormalisation group flow. This has led to ground-breaking results, such as the unprecedented determination of scaling dimensions in non-trivial CFTs including the celebrated Ising model in 3d. Thus far these endeavours have focused only on the simplest examples of correlation functions with low-spin operators or to supersymmetric CFTs. The project aims at advancing the goals of the CFT bootstrap further, by developing a combination of theoretical and numerical tools to systematically apply the bootstrap to correlation functions of higher-spin operators. The long term goal of TcCFT is to apply these tools to carve out the space of non-supersymmetric CFTs. Its short term objectives of developing effective techniques to manage higher-spin operators are of interest also in a broader context, for such operators are ubiquitous in any CFT. This proposal combines my expertise on higher-spin methods with world leading experts in the bootstrap program, and a secondment which will allow me to refine my programming skills needed for the computational parts of the project. The outcomes of the project will be critical in achieving a greater understanding of the landscape of quantum field theories, and with it allow me to proceed to the next step of my career and obtain a tenure track position in Italy.

Keywords: conformal field theory,holography,string theory
New Frontiers in Music Information Processing (MIP-Frontiers)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Austria,Spain,Austria,Germany,Spain,Sweden,France,France,Netherlands,United Kingdom,Luxembourg,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-04-01
End date: 2022-03-31
Duration (months): 48.0
Total project cost (EUR): 3926675.88
EU funding (EUR): 3926675.88
Participants: 17
Project status: CLOSED

Music Information Processing (also known as Music Information Research; MIR) involves the use of information processing methodologies to understand and model music, and to develop products and services for creation, distribution and interaction with music and music-related information. MIR has reached a state of maturity where there are standard methods for most music information processing tasks, but as these have been developed and tested on small datasets, the methods tend to be neither robust to different musical styles or use contexts, nor scalable to industrial scale datasets. To address this need, and to train a new generation of researchers who are aware of, and can tackle, these challenges, we bring together leading MIR groups and a wide range of industrial and cultural stakeholders to create a multidisciplinary, transnational and cross-sectoral European Training Network for MIR researchers, in order to contribute to Europe's leading role in this field of scientific innovation, and accelerate the impact of innovation on European products and industry. The researchers will develop breadth in the fields that make up MIR and in transferable skills, whilst gaining deep knowledge and skills in their own area of speciality. They will learn to perform collaborative research, and to think entrepreneurially and exploit their research in new ways that benefit European industry and society. The proposed work is structured along three research frontiers identified as requiring intensive attention and integration (data-driven, knowledge-driven, and user-driven approaches), and will be guided by and grounded in real application needs by a unique set of industrial and cultural stakeholders in the consortium, which range from consumer electronics companies and big players in media entertainment to innovative SMEs, cultural institutions, and even a famous opera house, thus encompassing a very wide spectrum of the digital music world.

Keywords: music information retrieval
Three-dimensional nanoscale design for the all-in-one solution to environmental multisource energy scavenging (3DScavengers)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Spain
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-03-01
End date: 2025-02-28
Duration (months): 60.0
Total project cost (EUR): 1498414.0
EU funding (EUR): 1498414.0
Participants: 1
Project status: SIGNED

Imagine a technology for powering your smart devices by recovering energy from lights in your office, the random movements of your body while reading these lines or from small changes in temperature when you breathe or go out for a walk. This very technology will provide energy for wireless sensor networks monitoring the air in your city or the structural stability of buildings and large constructions remotely and sustainably, avoiding battery recharging or even replacing them. These are the challenges in micro energy harvesting from (local) ambient sources. Kinetic, thermal and solar energies are ubiquitous at our surroundings under diverse forms, but their relatively low intensity and intermittent availability limit their potential recovery by microscale devices. These restrictions call for multi-source energy harvesters working under two principles: 1) combining different single-source harvesters in one device, or 2) using multifunctional materials capable of simultaneously converting various energy sources into electricity. In 1), efficiency per unit volume can decrease compared to the individual counterparts; in 2), materials as semiconductors, polymeric and oxide ferroelectrics and hybrid perovskites may act as multisource harvesters but huge advances are required to optimize their functionalities and sustainable fabrication at large scale. I propose to fill the gap between these approaches offering an all-in-one solution to multisource energy scavenging, based on the nanoscale design of multifunctional three-dimensional materials. The demonstration of an industrially scalable one-reactor plasma/vacuum method will be crucial to integrate hybrid-scavenging components and to provide 3DScavengers materials with tailored microstructure-enhanced performance. My ultimate goal is to build nanoarchitectures for simultaneous and enhanced individual scavenging applying photovoltaic, piezo- and pyro-electric effects, minimizing the environmental cost of their synthesis

Keywords: nanowires,nanoarchitectures,energy harvesting,energy scavenging,nanogenerator,solar cells,plasma assisted deposition,vacuum deposition
SOCRATIC: A real-time effluent management software based on artificial intelligence and industrial automation, specific for the prevention of combined sewage overflow (SOCRATIC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Storm water overflows (also known as Combined Sewer Overflow, CSO) can occur during small to heavy rainfalls, if there is no proper management of the storage capacity in combined sewer systems. The share of combined sewer is more than 50% in 10 European states. CSOs carry chemical and microbiological pollution, hazardous substances and waste affecting the quality of water and environment putting at risk human and animal health and aquatic life. Between 2014-2017, 3.130 pollution events affecting only bathing waters were reported (Source EEA). The Urban Waste Water Directive requires the Member States to “decide on measures to limit the pollution from storm water overflows”. Beneath the option to build new infrastructures to increase retention capacities, which is a long and expensive process, the solution is to manage efficiently and adapt instantly existing canalisation systems and storage tanks. Currently, storm water management systems that aim to implement the latter concept focus on flood protection, which occurs only with heavy rainfalls. Moreover, they are based on weather forecasts that are unreliable and not accurate and hydraulic simulation software that need high computing times up to 24h. The French SME IXSANE Sas with more than 20 years of experience in Environmental & Urban engineering has developed SOCRATIC, an innovative effluent management system specific for CSOs prevention, that works with accurate real time storm water levels, fast Artificial Intelligence simulation and automated processes. A low cost technology, which provides savings of up to 90% in comparison to the construction of new infrastructures. SOCRATIC will reduce by 80% the number of CSO events and by 60% the volume of leaks released into the environment. IXSANE will target the Municipal Water Market, precisely the Smart Water Segment, where the share of Software and Automation is worth 8.83 Billion € in 2017 with a CAGR of 33,9% (Source Frost& Sullivan).

Keywords: storm water management,combined sewer overflow,environmental protection,health risk,wastewater
Time Resolved THz Calorimetry explores Molecular Recognition Processes (THZCALORIMETRY)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany,Israel
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-10-01
End date: 2022-03-31
Duration (months): 66.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2100000.0
Participants: 2
Project status: CLOSED

Time-resolved THz-Calorimetry Explores Molecular Recognition Processes Definition: “THz-calorimetry is the science of measuring low frequency density of states kinetics for the purpose of deriving the entropy changes associated with biological processes in real time.” Goal: Our scientific vision is to introduce time-resolved “THz-Calorimetry” to access the entropy changes of the protein and the solvent accompanying enzymatic reactions or more general molecular recognition processes, i.e. under non-equilibrium conditions with envisioned time resolutions of nanoseconds. Advances in THz technology will make it possible to develop strong, ultrafast THz sources in the frequency range up to 10W that allow the detection of frequency-resolved transient low frequency spectra of biological samples with μsec or even nsec time resolution. We will correlate the transient THz spectra with changes in the entropy and enthalpy, both experimentally and theoretically. Ultrafast THz-calorimetry is an innovative tool to access to the specific transient entropy changes of molecular recognition processes under non-equilibrium conditions. Objectives of the proposal: 1. Monitor transient low frequency spectra (0-300cm-1) during molecular recognition processes. 2. Develop cutting edge experimental methods which allow the separation of protein and solvent modes under ambient conditions. Determine Delta S(protein(t)), Delta S(ligand(t)), Delta S(solvent(t)), thus specify the role of changes in the solvent entropy (hydrophobic effect) for biomolecular recognition. 3. Apply ultrafast THz-calorimetry: Explore the entropy changes of the enzyme, the ligand and the solvent for a family of MMP enzymes and substrates and correlate these results with biological function. Deduce underlying molecular mechanisms. 4. Develop new models for molecular recognition processes which are quantitative and predictive.

Keywords: thz spectroscopy
Data and document integrity for services provided through critical information infrastructures (Loca Credibilia)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Hungary
Call: Critical infrastructure protection topic 7: SME instrument topic: Protection of Urban soft targets and critical infrastructures (H2020-SMEINST-1-2015, 2015)
Start date: 2015-05-01
End date: 2015-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Loca Credibilia will promote increased security and public trust in the critical financial services infrastructure, assuring document integrity and accountability. Loca Credibilia will further limit trust destroying instances of forgery, fraud and corruption. The system is proved to be an important tool to identify objects and the changes of their relations, status in the course of a legally controlled life cycle. The information management system based on ADNS coding and processes provides information for all participants of the document lifecycle by enabling access to the last valid version.

Keywords: financial infrastructure,information infrastructure,document integrity
Light triggered non-invasive gene delivery through lipopolyplexes (LIGHTOPLEX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

Target-specific and controlled drug delivery are nowadays integral and extremely promising parts of research and practice in modern medicine. It gives an option to reduce drug toxicity and increase bioavailability by delivering a drug to a specific site with defined concentration. During the last decade highly efficient non-viral gene delivery has been achieved by encapsulation of nucleic acids into complexes of liposomes and polycations - lipopolyplexes (LPP) - new generation gene delivery systems. The main challenge in liposome-based gene delivery is to achieve high level of control over gene release. The main aim of this project is to develop a new approach for non-invasive gene delivery while gene release is highly controlled in space and time. This will be achieved by the design of infra-red light sensitive LPPs. The project includes engineering of the tailor-made LPPs, detailed investigation of the light triggered release mechanism, and will eventually result in intracellular light triggered gene delivery. Expert knowledge of the researcher together with the knowledge to be contributed by the hosting institution and from collaborations established by the researcher worldwide will allow successful project implementation. Mutual knowledge transfer will strengthen scientific contacts within and outside the EU as well as will let the researcher to develop her own independent research career. Attraction of interest from industrial partners is expected in case of success. Collaboration with industrial partners will profit from an exceptional record of the host with successful industrial projects.

Keywords: gene delivery,liposome,stimuli sensitive,multilayers,intracellular,controlled delivery,self assembly
Nanoassemblies for the subcutaneous self-administration of anticancer drugs (THERMONANO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: France
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-09-01
End date: 2024-02-29
Duration (months): 66.0
Total project cost (EUR): 1759414.0
EU funding (EUR): 1759414.0
Participants: 1
Project status: SIGNED

To counter the predicted drastic rise of new cancer cases over the next decades and to lower the dramatic financial burden of cancer treatments on patients and healthcare systems, innovative chemotherapies with high efficacy and reduced cost represent an urgent and unmet clinical need. Despite great enthusiasm for drug-loaded anticancer nanocarriers (e.g., liposomes, nanoparticles, micelles), their bench-to-bedside translation is not straightforward. Recent disappointments during clinical trials have fuelled concerns as to whether drug-loaded nanocarriers work any better than the free drugs. Thus, significant rethinking of drug delivery from nanocarriers seems inescapable. In the context of THERMONANO, I will develop a new drug delivery strategy that will be simple, efficient, comfortable for the patient and significantly less costly. The idea is to design drug-loaded nanoassemblies that can be administered subcutaneously to enable the self-administration of all kinds of anticancer drugs, including irritant and vesicant drugs. Not only could this approach lead to more easy-to-handle chemotherapies, it could also boost the development of at-home cancer chemotherapy.

Keywords: nanoparticles,polymer,progrugs,subcutaneous,cancer,metronomic chemotherapy