Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
IMAGHYNE: INVESTMENT TO MAXIMISE THE AMBITION FOR GREEN HYDROGEN IN EUROPE (IMAGHyNE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Innovation actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: France,Italy,Spain,Switzerland,Portugal
Call: Large-scale Hydrogen Valley (HORIZON-JTI-CLEANH2-2023-1, 2023)
Start date: 2024-01-01
End date: 2029-12-31
Duration (months): 72.0
Total project cost (EUR): 198925213.74
EU funding (EUR): 19996911.75
Participants: 46
Project status: SIGNED

IMAGHyNE will pave the way for the deployment of a large-scale renewable hydrogen (H2) economy in the Auvergne-Rhône-Alpes region, fully integrated in the energy system and addressing the needs of high emitting sectors. The objectives will be to: 1) deploy 62 MW of new electrolysis capacity, 2) implement a flexible H2 supply chain combining underground storage and tube-trailer deliveries 3) deploy 13 multi-modal H2 refuelling stations, 4) deploy 200 on-road fuel cell vehicles, 5) deploy 58 off-road fuel cell vehicles and stationary equipment, 6) strengthen the robustness of the energy and H2 supply chain by integrating a flexible industrial player, 7) design an efficient pipeline-based multi-user H2 ecosystem, 8) prepare for additional large-scale deployment as part of the Valley extension (including IPCEI) and its replication, 9) disseminate and communicate the results of the project to a wide audience. IMAGHyNE will meet the requirements of the Work Programme and contribute to the EU’s H2 strategy. IMAGHyNE will foster the development of a long-lasting H2 economy through: 1) an extension of the Valley including the development of a pipeline network and the transition of several industries part of the observer group, 2) an ambitious replication strategy with at least 5 territories from European countries (France, Italy, Spain, Portugal, Switzerland), and airports, 3) high quality communication and dissemination activities including training, 4) recommendations to public authorities on regulation (e.g. tunnels). This ambition will be achieved thanks to the involvement of key public and private entities covering the entire H2 value chain, with an extensive experience of EU-funded projects, who have defined a detailed governance structure, Work Plan and financing strategy. IMAGHyNE partners will work collectively to create links and synergies with upcoming and existing Valleys already supported by the Clean Hydrogen Partnership.

Keywords: electrolyser,hrs,renewable h2 supply chain,pipeline,tube trailer,underground storage,airport,mountain,industry,cross border,job creation,training,eu cooperation,industrial leadership
Service-oriented 6G network architecture for distributed, intelligent, and sustainable cloud-native communication systems (6G-CLOUD)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Smart Networks and Services
Action type: Research and Innovation actions
Partnership: SNS (JU-JTI)
Countries involved: Finland,Greece,Spain,Poland,Portugal,Switzerland,France,Germany
Call: System Architecture (HORIZON-JU-SNS-2023, 2023)
Start date: 2024-01-01
End date: 2026-06-30
Duration (months): 30.0
Total project cost (EUR): 4261968.75
EU funding (EUR): 3999938.38
Participants: 13
Project status: SIGNED

Service-based architecture in the 5G core network, disaggregated RAN, and network slicing are a few of the 5G network's innovative paradigms. There are however new requirements for 6G, such as the efficient use of integrated cloud resources, end-to-end network programmability, and the dynamic integration of multiple connectivity domains to realize intelligent connectivity across increasingly pervasive cloud environments. The 6G-Cloud project will research, develop, and validate key technologies to realize an artificial intelligence (AI)-native and cloud-friendly system architecture atop the cloud continuum. It will integrate cloud resources offered by multiple stakeholders and allow network functions from different 6G network segments to be composed flexibly and dynamically based on service needs in hybrid cloud environments. 6G-Cloud will address the following key topics: i) designing a holistic, AI-native service-oriented 6G system architecture atop a cloud continuum; ii) developing AI-driven cloud continuum and management frameworks and business interfaces for a multistakeholder environment; iii) defining an AI/machine learning (ML) framework for native-AI support in the 6G system; iv) supporting the 6G "network-of-networks" concept using service-oriented network design. 6G-Cloud will incorporate scalability, sustainability, resilience, and security requirements into system design. The concept will be validated by three well-defined proofs-of-concept and promoted through 6G architectural standardization work and open-source projects to reach maximum impact.

Keywords: 6g system architecture,cloud continuum,service based architecture,resource orchestration,native ai,control programmability,energy efficiency,ai ml framework
3 InDustrial Ecosystems tAckLing supply chains dISrupTions and boosting advanced technologies uptake (IDEALIST)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Coordination and support actions
Countries involved: France,Italy,Ukraine,Germany,Poland,Spain,Czechia
Call: Boosting generation and diffusion of advanced technologies in SMEs based on a supply chain model (CSA) (HORIZON-CL4-2023-RESILIENCE-01, 2023)
Start date: 2023-12-01
End date: 2026-11-30
Duration (months): 36.0
Total project cost (EUR): 2335852.84
EU funding (EUR): 2093511.77
Participants: 14
Project status: SIGNED

The overall objective of "3 InDustrial Ecosystems tAckLing supply chain dISrupTions and driving the adoption of advanced technologies" (IDEALIST) is to support SMEs in industrial ecosystems 1/ Energy-intensive industries, 2/ Aerospace and Defence, 3/ Mobility, Transport & Automotive in their ability to understand and adapt to changes brought about by rapid and unexpected developments in the world such as the COVID-19 crisis or the Russia-led war in Ukraine. These 3 sectors are of capital importance for the European economy and despite their specificity, have common challenges that the project will help to address: transition to more sustainable practices, competitiveness issues in a context of scarcer raw materials and more expensive energy, change in consumption habits. Being more resilient means giving SMEs the opportunity to be a player in these changes and no longer just a spectator or follower. To do this, the project will evolve around three pillars 1/ Strategic Foresight to establish relevant tools and behaviors to anticipate and better prepare for change in an orderly and systematic way, 2/ Technology Uptake to overcome obstacles related to the implementation work of Advanced Technologies and lay the foundations of alliances between tech-savvy and traditional SMEs and 3/ Supply chains to identify critical dependencies and weaknesses in order to limit the impacts of disruptions on value chains. This work will lead to the realization of Pilot Projects promoting the meeting between ecosystems, facilitated by the use of the Hack&Match method. The mobilization of the AGORA platform led by EIT Manufacturing will support this objective of matchmaking and community building. The project is carried by a relevant consortium of 14 partners from 6 European countries and Ukraine representing several thousand manufacturing companies. The project will take place over 3 years (36 months).

Keywords: energy intensive industries,aerospace and defence,mobility,strategic foresight,technology uptake,supply chains,digital and green transition
Redesigning the Primary Sector for Maximizing Bioeconomy Development (PRIMED)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Finland,Norway,Belgium,Portugal,Italy,Ireland
Call: Business models that balance the share of power and profit in the bioeconomy (HORIZON-CL6-2023-CIRCBIO-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 4704519.9
EU funding (EUR): 3999556.77
Participants: 13
Project status: SIGNED

The EU has a significant amount of waste biomass available, more than 900 million tons per year, and 98% of this material ends up in landfill, incinerators, or rotting in open dumps. According to the 2023 Circularity Gap Report, the global economy is now only 7.2% circular. The EU has great potential to convert bio-waste into bio-based products that can be used in multiple bio-applications. This revalorisation can directly support 5-10 times more employment and generate 4-9 times more added value than energy use. Circular Business Models in Bioeconomy (CBMB) face many challenges to become sustainable and profitable. Firstly, primary producers, the owners of the valuable feedstock, are often not integrated into the bioeconomy value chains, and they are often small scale and are fragmented, reducing their ability to negotiate with those higher up the value chain. The result is a suboptimal distribution of benefits and incentives. The main challenges in designing CBMB consist of: - lack of knowledge sharing and collaboration between stakeholders - need for new supply chains and logistical networks - difficult scale up of innovative technologies - understanding of the potential synergies and symbiotic relationships between sectors - overcoming poor public acceptance - complex and fragmented policy schemes, As a result of this, there is a lack of demonstrated and replicable systemic bio-solutions for the territorial deployment of the circular bioeconomy. The PRIMED Project PRIMED will co-create innovative forms of cooperation to integrate primary producers in novel bioeconomy value chains with a multi-actor approach. To do so, PRIMED will develop novel CBMB to produce high-value bio-based products through advanced biorefineries, and will demonstrate them in five Living Labs (LLab): PRIMED will also empower multi-actors to co-design a collaborative ecosystem to accelerate the bioeconomy, with an Open Access knowledge hub and toolkit (PRIMED digital toolbox).

Keywords: living labs,circular business models in bioeconomy,bio based value chains,primary producers integration in value chain,residual biomass transformation into bio based products
Towards a sustainable wellbeing economy: integrated policies and transformative indicators (ToBe)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Social and Economic Transformations
Action type: Research and Innovation actions
Countries involved: Finland,Sweden,Belgium,Spain,Ecuador,United Kingdom,France,Croatia,South Africa
Call: Public policies and indicators for well-being and sustainable development (HORIZON-CL2-2022-TRANSFORMATIONS-01, 2022)
Start date: 2023-03-01
End date: 2026-07-31
Duration (months): 41.0
Total project cost (EUR): 2698655.75
EU funding (EUR): 2698655.75
Participants: 15
Project status: SIGNED

ToBe aims to build an understanding of a sustainable wellbeing economy by developing integrated policies and transformative indicators. We contribute to theoretical and empirical knowledge in the field of sustainability transformation and advance understanding of sustainable wellbeing and inclusive economy beyond GDP. Together with researchers, policymakers and citizens in Europe, Africa and South America, we study how mindsets, indicators, innovations and policies could better work together towards the sustainability paradigm. We bring together green growth and postgrowth initiatives to create a novel understanding of economic growth. We also consider environmental and social justice when conceptualising sustainable wellbeing and identifying transformative indicators of a sustainable wellbeing economy. We provide new empirical knowledge on economic development, social outcomes and sustainability to address entangled societal challenges and to envision integrated policy solutions. All this contributes to an ecological macroeconomic model assessing integrated policy packages and to a synthesis typology of an accelerating sustainability paradigm. ToBe’s societal impact is linked directly to Europe’s policy goal of becoming a carbon-neutral continent by 2050. We will improve policy making capacity and coherence by exploring social and economic resilience and sustainability, as well as integrating different policies towards this end. The results will help create a sustainable and inclusive economy, as well as a shared vision for EU-Africa relations that build on sustainable growth. Our co-creation platform will strengthen epistemic communities to drive carbon-neutrality and tackle inequality and vulnerability in the context of entangled crises by a better understanding of trade-offs and synergies between economic growth and a sustainable wellbeing economy, including logics of change across different dimensions of sustainable development.

Keywords: sustainability,transformation,indicators,public policy,wellbeing,green growth,post growth,ecological macroeconomics,modeling
Key codE based on nanomatErials to Protect sErvices and pRoducts (KEEPER)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Italy,Austria,France
Call: EIC Transition Open 2022 (HORIZON-EIC-2022-TRANSITION-01, 2022)
Start date: 2023-06-01
End date: 2026-08-31
Duration (months): 39.0
Total project cost (EUR): 2111146.26
EU funding (EUR): 2111146.25
Participants: 6
Project status: SIGNED

Nowadays, counterfeit products seriously affect the global economy and can have a negative impact on security, health, and the environment due to the lower quality of their components. The severity of the problem is estimated to reach 2.3T$ in 2022, causing EU companies a loss of 121B€ in sales and more than 671 000 jobs. KEEPER project aims to provide a new technological solution for this challenge. KEEPER is the first system combining a unique identification code with a virtually infinite number of combinations (more than a septillion) to certify the authenticity of the product and an unprecedented level of security, ease of use, and low price. KEEPER is an innovative customizable solution based on two main assets: nano-engineered inks to be applied on documents or product packaging as adhesive tags or directly printed in specific spots (3Tag), and an extremely selective verification technique by means of a dedicated reader (3Check). The specificity of the inks and high-knowledge content make KEEPER technology extremely difficult or almost impossible to be replicated by reverse engineering processes. KEEPER intends to complete the technological development and to validate with industrial partners the impact on massive use cases increasing the TRL of the proposed solution, supported by a sound and implementable commercialization strategy. The first market considered is represented by the identity verification which is worth more than $10B globally and is expected to grow to $20B by 2022 according to research conducted by McKinsey. The strong integration of a technology track and a business track and a multi-actor approach, that will bring together key actors of academia and industry sector, will allow to deliver project-specific objectives and enable alternative directions and options. In the last phase of the project, we will proceed to the establishment of a start-up that will have the future objective of consolidating our presence in the reference market.

Keywords: anticounterfeiting,security tags,nano engineered inks,customized reader,id cards,pilot,authentication,unique code
Endogenous Human Herpesvirus: Germ line integration and effects on host cell and organism (ENDo-HERPES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and I mmunotherapy
Panel description: The immune system , related disorders  and their mechanisms , biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases , innovative imm unological tools and approaches , including  therapies
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Endogenous viruses present in the human genome control physiological processes, modulate aging, and can cause diseases. Intriguingly, a herpesvirus has entered the human germ line by integrating its genome into telomeres of germ cells and is present in about 80 million people. The virus, human herpesvirus 6 (HHV-6), can reactivate from the integrated state, which is associated with a number of diseases. These include seizures, encephalitis, heart failure and graft rejection. We recently analysed the virus genomes present in hundreds of individuals with this inherited chromosomally-integrated HHV-6 (iciHHV-6). The data show that today’s endogenous virus sequences are quite diverse and derived from dozens of independent integration events that were passed on for generations. There are critical gaps in our knowledge on the functionality of iciHHV-6 genomes with respect to virus replication, gene expression and latency, its effects on the host cell, and the role of telomere shortening that occurs during aging on virus reactivation. ENDo-HERPES will make use of novel technology to close these gaps and provide the basis for elucidating whether diseases are associated with or caused by iciHHV-6. Specifically, we will 1) identify which iciHHV-6 genomes are still functional and could contribute to disease development; 2) determine iciHHV-6 integration sites within the highly repetitive telomere region and assess the integration and reactivation process on the DNA level; and 3) investigate the effects of the iciHHV-6 genome on host cells and if telomere shortening can induce reactivation. The proposal utilizes state-of-the-art technology and pioneers new approaches, particularly when investigating the integration sites of endogenous virus genomes and the mechanisms facilitating integration and reactivation. Altogether, we will shed light on the life cycle and effects on the host cells of this endogenous herpesvirus present in the genome of about 1% of the human population.

Keywords: endogenous herpesvirus human herpesvirus 6 roseola infantum,icihhv 6 integration telomeres latency cas9 targeted nanopore sequencing
Personalized Adjuvant Treatment for HR+/HER2- breast cancer FOR YOUNG patients (PATH-FOR-YOUNG)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: France,Belgium,Italy,Netherlands,United Kingdom,Greece,Ireland,Argentina,Peru,Slovenia,Spain,Poland,United States,Brazil,Australia
Call: Comparative effectiveness research for healthcare interventions in areas of high public health need (HORIZON-HLTH-2024-DISEASE-03-two-stage, 2024)
Start date: 2025-01-01
End date: 2031-12-31
Duration (months): 84.0
Total project cost (EUR): 9688005.47
EU funding (EUR): 9498603.68
Participants: 27
Project status: SIGNED

Worldwide, ~7 million women live with or beyond Breast Cancer (BC), as 10-year survival rates exceeding 80% for early-stage (I-III) BC. Premenopausal BC accounts for 25% in the EU and 55% in low/middle income countries. Most premenopausal women with BC have high risk of recurrence, therefore standard treatment includes adjuvant chemo- (CT) and endocrine therapy (ET). However, treatment has substantial physical, emotional and social burden, which is often more pressing for younger compared to older patients. Gene-expression assays are used for post-menopausal patients to identify women who can safely forego CT without detriment on clinical outcomes, preserving Quality of Life (QOL). However, a definitive study has yet to be conducted among premenopausal women with high-risk HR+HER2-BC. The primary objective of PATH-FOR-YOUNG is to conduct a pragmatic randomized controlled trial (RCT) with 5000 patients validating the use of a gene-expression assay to drive adjuvant treatment decisions in this target population. PATH-FOR-YOUNG aims to achieve its objective in 7 years. The project (i) builds on and complements an ongoing twin RCT to ensure timely recruitment, (ii) leverages on a large international consortium of oncologists, pathologists, patient representatives, psychologists, sociologists, ethics and communication experts, biostatisticians, health economists, and technology providers, to assure complementary and multidisciplinary expertise, and (iii) highlights patient-engagement, participatory care, and early involvement of end users. PATH-FOR-YOUNG will also study implementation of digital self-management to support patients throughout the cancer journey and particularly while on ET to improve QOL and medication adherence. A full HTA will ensure a path towards cross-country implementation. PATH-FOR-YOUNG has the ambition to improve BC care, fully integrating the predictive, personalized, preventive, and participatory principles of health management.

Keywords: breast cancer,personalized treatment de escalation,quality of life premenopausal women,patient empowerment,participatory care,digital health