Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Modernism and Illness Experience: Embodied Strategies of Textual Production (ModIX)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-04-01
End date: 2028-03-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

The role that ill health plays in thematic concerns of modernist literature has been a topic of scholarly interest in recent years. Less considered, however, is the relationship between ill health and modernist practices of writing. The primary research aims of ModIX are to provide a sound methodology for exploring this relationship and to define modernist writing strategies and accommodations as they relate to authors’ illness experiences. Methodologically innovative, ModIX applies affect theory to genetic criticism in order to trace the author’s body as a tool and facilitator of writing. The project focuses on three key modernist authors who experienced illness to a life-altering degree: James Joyce (1882-1941), D. H. Lawrence (1885-1930) and Katherine Mansfield (1888-1923). Drawing together insights from affect theory, health humanities and archival studies, ModIX will reconstruct the literary geneses of Joyce’s Finnegans Wake, Lawrence’s Lady Chatterley’s Lover and selected short stories by Katherine Mansfield, all written during periods of the authors’ ill health and needs for care. ModIX’s research objectives are to consolidate affective genetic criticism as a methodology, to understand modernist illness experience phenomenologically, and to reconstruct the networks of care that surrounded these modernists as a result of ill health and creative needs. ModIX goes beyond the state of the art to understand the lived experience of illness not only as a biographical fact, but as a dynamic, material factor in shaping, facilitating and sometimes frustrating modernist literary labour and production. ModIX is an archival project that will produce original and impactful results. The project outputs will include three peer-reviewed articles in high quality journals, a monograph proposal, and a research summit to form the basis for a large-scale interdisciplinary ERC project on illness experience and literary production.

Keywords: genetic criticism,affect theory,health humanities
Advances in Empirical Methods for Time Series and Forecasting in Unstable Environments (TIMESERIESFOREC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: Spain
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-07-01
End date: 2028-06-30
Duration (months): 60.0
Total project cost (EUR): 859950.0
EU funding (EUR): 859950.0
Participants: 1
Project status: SUSPENDED

The environment we live in is both complex and time varying. Examples of recent instabilities include the recent financial crises as well as the more recent COVID-19 pandemic and the war in Ukraine, which have substantially altered our world. Currently, however, the way researchers implement forecasts as well as the way they estimate the effects of economic policies is based on methods that either impose restrictive assumptions on the nature of instabilities or quickly become computationally demanding in the presence of instabilities. This project proposes to develop a local projection-based estimator for time-varying parameter models and their impulse response functions in unstable environments, which we refer to as the “time-varying parameter local projection” estimator (or “TVP-LP” in short). The proposed estimator is expected to provide a feasible approach to conveniently and flexibly estimate economic models in unstable environments as well as, more broadly, forecasting and assessing the effects of economic policies. The proposed estimator can be generalized to include instrumental variables as well as be applied in vector autoregressive models with external instruments while being robust to the presence of instabilities. The proposed methodology is expected to have widespread applicability given the increasing interest in using convenient local projection estimators and the substantial evidence of instabilities in macroeconomic models. In contrast to conventional time-varying parameter VAR models, the proposed time-varying parameter local projection estimator is robust to the presence of non-invertibility due to omitted variables and misspecification and its estimation is less computationally challenging. The advantages of the methodology will be illustrated in terms of forecasting ability as well as the evaluation of the effects of economic policy (in particular, fiscal policy).

Keywords: time series econometrics,forecasting,macroeconometrics
Democratizing access to Quantum limited microwave parametric AMPlifiers (QuAMP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Switzerland
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2025-POC, 2025)
Start date: 2025-12-01
End date: 2027-05-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Amplifiers are essential in science and technology – they are needed to overcome the detection threshold of sensors, like antennas, detectors or even our ears. When a signal is weak or generated at a distance, amplification becomes necessary. However, amplification adds noise, and if noise exceeds the signal, detection becomes impossible or needs heavy post-processing, limiting applications that rely on weak signals or high sensitivity. Over the last century, amplifiers have evolved to reduce noise, from vacuum tubes to transistors. More recently, quantum technologies exploiting the laws of quantum mechanics to outperform their classic counterparts, have emerged. In this fast-growing field, traditional low-noise amplifiers still add too much noise and do not suit scalable cryogenic platforms. Quantum-limited microwave amplifiers, which add minimal noise, are key instruments in quantum computing, radio astronomy, and particle physics. Despite their central importance, the availability of quantum-limited amplifiers remains severely constrained by fabrication complexity, limited reproducibility, and poor scalability. Current commercially available traveling-wave parametric amplifiers (TWPAs) rely predominantly on electron-beam lithography, a slow and costly technique incompatible with large-scale production and industrial deployment. This represents a fundamental bottleneck in the democratization and technological maturation of quantum-limited microwave amplification. This project proposes a novel fabrication method using Deep Ultraviolet Lithography (DUV) – an industry-standard, scalable process – to produce better-performing TWPAs at lower cost and larger volumes. By using DUV, the goal is to create high-performance amplifiers with minimal noise, pushing the boundaries of quantum-limited amplification and enhancing high gain with the aim to have a ready-for-market TWAP by the project's end.

Keywords: traveling wave parametric amplifiers twpa,quantum limited amplification,josephson junction
GREEN PROCESSING AND VALORIZATION OF ORGANIC BY-PRODUCTS OF DISTILLERIES, AS NOVEL APPROACHES FOR CLIMATE-SMART PROTEIN APPLICATIONS FOR ALTERNATIVE FOOD AND CIRCULAR BIO-ECONOMY (BionovFOOD)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy,Sweden
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 2
Project status: CLOSED

Food systems have created demand for addressing adequate nutrition, safe, healthy, accessible, and affordable food, under the pressure of increasing trend of the global population (projected to reach 10 billion by 2050), climate changes, pandemics, economic crisis, growth in the dietary supplements segment and many more. Sustainable and cost-efficient development of innovative food sources are needed to meet the projected nutrition demand, which have recently attracted the attention of both producers and consumers. Conversely, the significant losses and waste production by the processing industries are becoming a serious nutritional, economical, and environmental issue. The aim of BionovFOOD project is to propose novel approaches to valorize the distillery organic by-products and to include them into a biorefinery system. These will be used as raw materials in processes aimed at the recovery/separation of bio-products, with a focus on the production of proteins for food application. To reach this goal will be developed on a pilot-demo scale, process concepts for bio converting grape marcs, wine lees and vinasse, generated from the distillery industry, into protein-rich ingredients to be used for the production of alternative food products. Life cycle assessment and techno-economic aspects for the production of protein sources produced from edible and safe fungi will be investigated. With proteins produced will be designed and developed novel food. BionovFOOD project constitute the starting point for the understanding that distilleries’ by-products can significantly contribute to the future production of alternative protein-rich fungal biomass for food applications. Indeed, it will create synergies and co-benefits across 4 priority areas: nutrition and healthy diets; climate and environment; circularity and resource efficiency; and innovation. This project is a unique opportunity for my career and will boost my scientific profile.

Keywords: alternative protein distillery by products circular bioeconomy fungi biomass novel food
Rise and Demise of Industrial Modernity (RiDe)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Estonia
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-05-01
End date: 2030-04-30
Duration (months): 60.0
Total project cost (EUR): 1990195.0
EU funding (EUR): 1990195.0
Participants: 1
Project status: SIGNED

Contemporary societies are underpinned by industrial modernity: a set of commonly shared ideas, institutions and practices related to the natural environment and technoscience. Having historically unleashed massive leaps in productivity, economic growth and societal welfare, many traits of industrial modernity have now become maladapted to the current socio-ecological polycrisis. As a result science and technology promise to solve the grand challenges of climate change, resource depletion and loss of biodiversity with one hand, only to keep intensifying them with another. There is thus a fundamental need to rethink industrial modernity. Attempts to detect signs of this fundamental shift currently remain fragmented within and between disciplines like sustainability science, innovation studies, or history of technology. RiDe will use a new Deep Transitions framework from the sustainability transitions field to provide an overarching synthesis on the acceleration, crisis and transformative prospects of industrial societies from 1900 to the present. It focuses on 3 questions: 1) what are the major historical continuities and emerging ruptures in industrial modernity? 2) what are the mechanisms through which technoscience keeps blocking transformative environmental practices? 3) in which countries is major transformative change most likely to occur? RiDe will 1) use a mixed method research design, combining text mining, databases, stylized narrative explanation, and process-tracing, which; 2) enables it to discover new empirical patterns in the evolution of industrial modernity, and; 3) develop a composite index for identifying countries currently least hindered by the historical legacy of industrial modernity. The results will be synthesized into the first macro-level middle-range process theory in transitions studies, offering a new comprehensive, historically-informed and empirically-backed interpretation of industrial modernization for sustainability science.

Keywords: sustainability transitions sustainability science deep transitions industrial modernity mixed methods
Magnetically Levitating Inertial Force Transducer (MAGLIFT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2025-POC, 2025)
Start date: 2026-02-01
End date: 2027-07-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Autonomous vehicles rely on GPS-based navigation, but in GPS-denied environments like tunnels, dense urban areas, and parking garages, they need high-precision accelerometers to stay on course. While current MEMS accelerometers provide a potential solution, they lack the necessary sensitivity, and their high-end alternatives are too expensive for mass production. To address this, I propose a magnetically levitating accelerometer that leverages magnetic force to keep the proof mass in a highly sensitive floating state. This approach enables high-resolution motion detection while reducing power consumption and fabrication expenses. MAGLIFT will convert acceleration and position changes into electrical signals via a PCB-based sensing system, offering a compact, low-cost alternative to the state-of-the-art accelerometers. Building on insights from the ERC Consolidator Grant NCANTO (101125458), which focuses on taming mechanical noise in nanomechanical systems, I realized that our state-of-the-art noise suppression and nonlinear dynamic optimization solutions can significantly enhance the performance of magnetically levitating mechanical objects. By integrating NCANTO’s dynamic range improvement and advanced noise reduction techniques, I aim to develop an accelerometer with record-breaking performance, ensuring precise, reliable navigation for autonomous vehicles. MAGLIFT will further evaluate market potential of this technology and benchmark it against existing solutions to determine the optimal strategy for market entry.
ERA Chair Life Sciences Program to EmpoweR moleculAr aNd struCtural biology initiativEs at UPAT (ESPERANCE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Coordination and support actions
Countries involved: Greece,Netherlands
Call: ERA Chairs (HORIZON-WIDERA-2022-TALENTS-01, 2022)
Start date: 2023-02-01
End date: 2028-01-31
Duration (months): 60.0
Total project cost (EUR): 2499017.5
EU funding (EUR): 2499017.5
Participants: 2
Project status: SIGNED

UPAT is the third largest university in Greece and widely recognized as an excellent knowledge and research hub. The UPAT Departments of Medicine and Pharmacy reached their high standards by combining efforts of their cell biology, biophysics and structural biology research teams. In fact, their broad set of state-of-the-art equipment was recently combined into a national research infrastructure, also operating -albeit at modest level- in European biomedical and structural biology initiatives. Thus far, the huge research and innovation potential of these UPAT groups are not yet fully exploited. The ESPERANCE project therefore aspires to expand and intensify their concerted actions by adding a part-time ERA Chair holder. This new group for ‘integrative molecular biophysics and structural biology’ will glue together the current research and education environment by boosting collaborative science and providing synergy. He will participate in training and be instrumental in developing UPAT’s national and international visibility by boosting translational research and open access opportunities for the UPAT research facilities. To achieve such ambitious goals, a very talented, respected, internationally operating Greek biophysicist, structural biologist and research facility architect from The Netherlands Cancer Institute has been attracted. Supported by his skilled local staff, he will participate in many activities to optimize local strategies for the UPAT research groups and infrastructure towards future sustainability. ESPERANCE incorporates elaborate programs for training early career scientists, for attracting funding and talent, for collaborative actions with industry and for institutional restructuring. The development and enhanced capacity for the UPAT equipment will form an example for other local and nation-wide research infrastructures, and extent UPAT’s excellence, visibility, and competitiveness to benefit Greek research in the European Research Area.

Keywords: excellent research,strengthen human capital in randi,address eu priorities,strengthen randi uptake in society,innovation based growth,qualified researchers and better jobs,leverage investments inrandi
NanoBiCar: A novel immunotherapy for infectious diseases (NanoBiCar)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain,Israel,France,Netherlands
Call: EIC Pathfinder Open (HORIZON-EIC-2024-PATHFINDEROPEN-01, 2024)
Start date: 2025-02-01
End date: 2028-01-31
Duration (months): 36.0
Total project cost (EUR): 2999101.25
EU funding (EUR): 2999101.25
Participants: 11
Project status: SIGNED

It is estimated that 20% of global mortality is associated with bacterial infections. The current treatment is based on the use of antibiotics, but nonspecific effects, difficulty in reaching intracellular bacteria, and the generation of antimicrobial resistance limit its effectiveness. Tuberculosis (TB) is the leading cause of mortality due to a single infectious agent: Mycobacterium tuberculosis (Mtb). Multidrug-resistant TB (MDR-TB) is a major threat to global health security. A quarter of the population is latently infected with Mtb, many of them MDR strains, so preventing new cases of this growing reservoir is a priority. Immunotherapy is an alternative option, but its effectiveness is based on the immune response capacity of a compromised host. NanoBiCar's long-term vision is to revolutionize the current treatment of bacterial infections with a groundbreaking and innovative immunotherapeutic approach, overcoming many of the problems associated with treatment, with potential application beyond this field. Using TB as a proof of concept, three immunotherapeutic platforms, using mRNAs encapsulated in lipid nanoparticles, not tested in bacterial diseases will be used to eliminate intra (IC) and extracellular (EC) bacteria. These immunotherapeutic methods are safe, economical, accessible, ready-to-use, and specific, targeting latent/ acute/chronic infections, without generating resistance and suitable for use in high-burden, low-resource settings; effective regardless of the antibiotic resistance of the strain and its niche (IC or EC), the genetic background of the host and the degree of immunocompetence.

Keywords: tuberculosis,infectious diseases,immunotherapy,mrna lipid nanoparticles
The biology of syncytial cells: Dissecting the mechanisms and functions of nuclear differentiation inside skeletal muscle syncytium (SyncyNucDiff)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cell Biology, Development, Stem Cells and R egeneration
Panel description: For all organisms : Structure and function of the cell, cell -cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-12-01
End date: 2027-11-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 2
Project status: SIGNED

Due to their cellular anatomy, syncytial cells face many unique challenges that mono-nucleated cells do not. One of them is how syncytial cells organize gene expression among many nuclei in a shared cytoplasm. How such property is linked to their biological functions remains poorly understood. Using the skeletal muscle as a paradigm and single-nucleus transcriptomics, I recently uncovered previously unrecognized diversity and dynamics of myonuclear transcriptional programs. This conceptualized the syncytial muscle cell itself as an analog of multi-cellular tissue where individual nuclei are counterparts of differentiated cell types. My findings raise two important and unanswered questions. 1) How are the diverse nuclear identities specified and maintained? And 2) What are the functional contributions of the diverse nuclear subtypes in health and disease? I will first focus on the nuclei at the neuromuscular junction (NMJ) and myotendinous junction (MTJ), which are responsible for initiation of contraction and dissipation of contractile force, respectively. Despite their well-established functions, the mechanisms that specify or maintain them are sparsely understood. I will investigate how chromatin architecture and transcriptional regulators govern their identities. I will then characterize the upstream signalling pathways from motor neuron or tendon cells that activate the specific transcriptional programs. So far, genetic manipulation of myofibers have targeted entire muscle nuclei. To overcome this limit, I will develop tools that allow genetic manipulation in specific nuclear subtypes. Previous works had identified a new nuclear subtype associated with muscular dystrophy and a transient time window during postnatal development. I will characterize the function of these nuclei using a method that abolishes their transcriptional activities. The approaches to be developed here will pave the way to understanding the pathophysiology of syncytial cells in the future.

Keywords: skeletal muscle,differentiation,neuromuscular and myotendinous junction,muscular dystrophy