Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A novel optical sensor platform for detection and measurement of contaminants in gas pipelines to protect critical infrastructure from disruption and damage - Linevu (LineVu)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: United Kingdom
Call: Critical infrastructure protection topic 7: SME instrument topic: “Protection of Urban soft targets and urban critical infrastructures” (H2020-SMEINST-1-2014, 2014)
Start date: 2015-03-01
End date: 2015-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Pipelines have formed an integral part of our Natural Gas transportation critical infrastructure for decades and their importance is growing, as resources reduce and new markets and demand open up. Liquid contamination in pipelines is a serious issue for safety, security, reliability of supply and commercially for gas supply and transportation companies. Existing technology is designed only to analyse dry gas. Liquid contamination damages the analysers and sample systems and there is no indication of the quantity of liquid present. Early detection of contamination is key and will result in the issue being dealt with before it becomes a commercial problem and most importantly an urgent safety or security issue. The Linevu system introduces a non-intruding vision system at various points in the pipeline in order to determine if a liquid is present in the pipeline, so that the correct course of action can be decided upon before it becomes a serious issue. Our goal is to embark on a phase 2 project in order to bring to market a novel pressurised window, containment system and vision system which can confirm the presence of liquid, while not interfering with routine “pigging” maintenance in the pipeline. The safety, economic and social benefits are numerous and the system would be retro-fitted onto any existing pipelines in the global supply network. At a time of great change in the global energy industry in terms of changing sources of gas and security of energy supply, we believe that this innovative technology will provide the EU with a real competitive advantage in the global energy supply market and oil & gas multinationals such as Exxon, Statoil, BP and Shell have already shown great interest in the concept.

Keywords: natural gas pipelines damage corrosion analysis transportation vision
Cost-ORiented Agile Localisation (CORAL)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2015, 2015)
Start date: 2015-07-01
End date: 2015-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

E-commerce businesses and SMEs have realised that globalisation is essential for their commercial growth and key for being resilient against crises in local markets. When an e-commerce decides to go global, translation is probably the most critical asset. In fact, recent studies show that about half of the consumers would never buy at websites where the information is not available in their language. However, SMEs face important economical and technological barriers that prevent their websites to be appropriately translated into the languages of their potential consumers, leaving many business out of the global market. This is an important loss, given the dimensions of the e-commerce market ($1,552 bn in 2013) and its growth rate (up to 33% from 2010 to 2015 in some regions). Currently e-commerces attempting to solve this problem can opt for: 1) professional or crowdsourced translation services, often perceived as too expensive; 2) inexpensive machine translation (MT) services whose quality is not enough to achieve consumer trust. Project CORAL will provide an innovative cost-oriented translation service that will allow e-commerces to adopt a lean strategy when entering a new market, by providing a fine-grained compromise between quality and cost. This will be achieved by using proprietary technology that 1) discovers the most important texts, at the page level, that should be assigned to human translators; 2) lowers the cost for less important texts by using specialised MT. Using a pay-as-you-go approach, CORAL will provide cost-effective internationalisation. This unprecedented flexibility will allow SMEs of any size to enter new international markets without the current economical barriers. During Phase 1 we aim at finding early adopters that help us assess the revenue streams and product/market fit, and ensure economical viability. In Phase 2, we plan to bring the product from TRL6 to TRL9 by following the guidance provided by our early adopters.

Keywords: localisation,e commerce,international markets,pay as you go
Enhancing the Innovation Management Capacity of SMEs (by EEN), Slovenia (We4SMESLO_3)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Slovenia,Slovenia,Slovenia
Call: H2020 2D CONSULTATION EEN (H2020-EEN-SGA2-2017-2018, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 117237.5
EU funding (EUR): 117236.0
Participants: 8
Project status: CLOSED

The EC has within its Survey of 2011, carried out on request of DG Enterprise and Industry (DG EI), realized that the main barriers of innovation in the eyes of the SMEs, are lack of financial resources and inability to manage innovation process. Since different understandings of the term "Innovation Management System" (IMS) have been noted the EC has supported European Committee for Standardization to provide the stakeholders with a unified definition of relevant parts in the IMS. According to this definition the most important parts of IMS include company's innovation processes from idea generation to innovation result, but also leadership, management skills and other enabling factors, like the ability to cooperate with third parties like RD partners, clients, and suppliers. The objective of this project in Slovenia is to enable SMEs to bridge the knowledge gap in innovation management, get aware of shortages and improve their internal innovation management system and/or focus on achieving market value with their inventions. The consortium will achieve this objectives with providing: 1.) Enhancing the Innovation Management Capacity of SMEs. The beneficiaries will receive diagnostic of their innovation system based on the standardized IMP³rove tool. This will lead to the formation of tailored action plan to improve the SME’s capacity to better manage innovation. 2.) Key Account Managers – Facilitators for the H2020 SME Instrument. Key Account Managers will identify and source appropriate lead coaches (from predefined pool of coaches), facilitate linking the SMEs to innovation support services and to support the lead coach in delivering services to the SME. The SME Instrument participants will receive the most appropriate services and support to enhance the probability of successful exploitation of the innovation project and to leave a footprint for the future sustainable growth of these beneficiaries.

Keywords: enterprise europe network,innovation management capacity,smes,coaches
Photopharmacology: From Academia toward the Clinic. (Photopharm)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Netherlands
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2020-01-01
End date: 2021-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

''Photopharmacology: from academia toward the clinic'' aims at the development of our platform technology from an academically emerging field towards a technology which has proven clinical applicability. Within this project novel photopharmacological targets will be evaluated and investigated. Additionally, in vivo proof of concept will be generated to make our technology ready for further clinical validation.

Keywords: photopharmacology,drug development,photoswitches,molecular motors,light,azobenzene,cancer,antimicrobials,synthetic chemistry
Intracellular signalling by modified lipopolysaccharide (skILL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-04-25
End date: 2021-04-24
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

The adjuvant potential of bacterial lipopolysaccharide (LPS) for vaccines depends on a detailed understanding of its innate immune signalling properties, in order to achieve the right balance between immunogenicity and reactogenicity. By biosynthetic engineering of meningococcal LPS, we have obtained a unique panel of mutants covering a wide range of endotoxic activity, from the maximum wildtype level to almost totally inactive. However, this is based on activation of the TLR4/MD-2 receptor, and recent studies have revealed that LPS endotoxic activity is also mediated by the intracellular receptor caspase 4 (caspase 11 in the mouse). At present, it is not clear how this contributes to the overall biological activity of LPS, and how it can be modified by structural alterations to the lipid A moiety of LPS. A major contribution of the proposed project will be to provide for the first time a detailed structure-function relationship for this LPS-caspase 4/11 interaction. This information will be crucial in the further evaluation of the adjuvant potential of these LPS derivatives, as well as giving more insight in the role of LPS modification in the interaction of pathogenic bacteria with the innate immune system. LPS mutants with differential effects on the TLR4 and caspase pathways will provide a unique opportunity to tease apart the contributions of both pathways to the overall LPS biological activity. In addition, we will explore the role of delivery of LPS by OMVs (outer membrane vesicles) to the intracellular pathway activation. A second and complementary contribution will be the development of novel LPS purification methods, which will also lead to better understanding of LPS structure-function relationships by allowing the separation of complicated LPS mixtures in their individual molecular species. In addition, they will pave the way for purification procedures which can be upscaled for making clinical grade LPS in human vaccine applications.

Keywords: vaccine,bacterial outer membrane,lipopolysaccharide,adjuvant,innate immunity,immune signalling,neisseria meningitidis
Maximization of amplification of next-generation RNA replicon vaccines through synergistic molecular and formulation design (RNAmpMax)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-02
End date: 2021-01-01
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

As a Maria Skłodowska-Curie Fellow, I aim to develop formulated next-generation RNA replicons that are designed to overcome the limiting initial type I interferon response that inhibits amplification and protein expression. RNA replicons are currently a cutting edge nucleic acid platform for delivery of vaccines and therapeutics, as they do not require penetration into the nucleus like plasmid DNA, but possess self-amplification properties that results in more efficient protein expression than messenger RNA. While pDNA and mRNA have have demonstrated excellent results with low doses when tested in mice doses must be scaled up by two orders of magnitude to mirror these effects in nonhuman primates. This disparity reflects a non-linear dose-response relationship, where increased doses are associated with triggering of an interferon cascade which restricts protein expression. Under the supervision of Prof. Robin Shattock, a world leader in translational vaccines and clinical trials at Imperial College London, I aim to overcome this translational barrier for RNA replicons by focusing on maximizing protein expression. I intend to engineer synergistic increases in the amplification of RNA replicons through a combination of molecular modifications designed to minimize interferon response and co-delivery with synthetic single-strand oligonucleotides known to inhibit the interferon pathway. These molecular adaptions will be paired with a novel delivery polymer that directly incorporates oligonucleotides into the RNA polyplex, thus ensuring co-localization: to be synthesized in collaboration with Prof. Molly Stevens, a world leader in polymeric biomaterials, during a secondment at the Karolinska Institutet. This project is the first demonstration of synergistic molecular and formulation design to address the non-linear dose-response relationship, and could impact scalability of RNA vaccines and therapeutics making them more affordable and available in Europe and worldwide.

Keywords: rna vaccine,nucleic acid formulation,immunoengineering
EU Surface Temperature for All Corners of Earth (EUSTACE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: Research and Innovation actions
Countries involved: Switzerland,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom,Denmark,United Kingdom,United Kingdom
Call: New ideas for Earth-relevant space applications (H2020-EO-2014, 2014)
Start date: 2015-01-01
End date: 2019-03-31
Duration (months): 51.0
Total project cost (EUR): 2954918.75
EU funding (EUR): 2694968.75
Participants: 10
Project status: CLOSED

EUSTACE utilises Europe’s capacity for gathering space-borne observations of the skin temperature, of all components of Earth’s surface, by extracting data relevant to providing estimates of surface air temperature, a primary Essential Climate Variable (ECV), conventionally measured at (often sparse) meteorological stations. EUSTACE will use measurements from operational and research satellites to enable estimates of surface air temperature to be made everywhere on Earth at higher spatial and temporal resolution than previously possible. The surface air temperature ECV is so fundamental to understanding our climate, that this will innovatively enable Europe to address its key societal challenges. The global coverage of space-borne observations of surface skin temperature will allow EUSTACE to estimate surface air temperature for parts of Earth that are not currently or historically observed by meteorological stations. EUSTACE will combine previous research experience, with the wealth of surface skin temperature retrievals now available, to produce estimates of surface air temperature over the whole of Earth, including the Poles. EUSTACE will then use these to develop new derived data products, i.e. globally complete analyses with estimates of associated uncertainties using new analysis methods developed within the project. Through the engagement of appropriate “trail blazer” users, EUSTACE will enable integration or assimilation of the products into applications related to Earth system sciences, forecasting models and other user sectors. EUSTACE will develop an automated system for surface air temperature products that is capable of being sustained after its lifetime. All development work will be undertaken on the same IT platform and all code secured within a central code repository. The design of the EUSTACE system will also account for on-going availability of observations from existing sources and planned availability of information from next generation sensors.

Keywords: surface air temperature,uncertainties,globally complete,centennial scale
Using existing methods to develop a modular, integrated and autonomous ‘Factory-in-a-box’ production line for manufacturing high volumes of flexible integrated logic circuits (FlexLogIC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: United Kingdom
Call: Accelerating the uptake of nanotechnologies, advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2015, 2015)
Start date: 2015-09-01
End date: 2015-11-30
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

We are Pragmatic Printing Ltd; we are pioneering the innovation in the field of flexible printed electronics. We are recognised by global firm ARM HOLDINGS for our disruptive and compelling solution for embedded connectivity in everyday objects. Our ‘flexICs’ are revolutionary integrated circuits manufactured on organic (plastic) substrates (instead of silicon) through our novel processes. Our flexICs are; thinner than a human hair; ultra-flexible; offered in flattering form factors and footprints that conventional silicon cannot achieve. Our processes allow flexICs to be produced on a large scale at a low cost; the marginal cost per IC in volume production can be <€0.01. Being silicon-free can bring many new potential applications. The flexible and visually unobtrusive flexICs are ideal to be integrated onto goods packaging, controlled documents and the like. Given the exponential growth in the demand for the ‘Internet of Things’ connectivity, our flexICs are ideal to fulfil the demand in a cost effective manner. In order to facilitate this demand, we want to empower packaging printers and manufacturers with the integrated ability to produce these ICs at the point of packaging manufacture and integration. There is a strong documented need and market demand pull from market leading companies such as Crown Packaging, Cartamundi, Molex and Smartrac and others for an integrated solution for the manufacture of flexICs onsite. We wish to take our existing production processes, and package them in an automated, modular and integrated self-contained ‘factory in a box’. This FlexLogIC plant will allow packagers to manufacture ICs onsite in an efficient and effective way. The FlexLogIC plants will help us to achieve our objective of generating €70 million turnover in year 5 post project. We are the only ones currently that have the ability to supply a self-contained, autonomous ‘factory in a box’ to facilitate the high volume manufacture of flexible printed ICs.

Keywords: logic,integrated circuits,flexible,printed electronics,ultra thin,intelligence,smart,internet of things,integration
Services provided by Cinema foR ImPlementing new acTion (SCRIpT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Italy,Italy,Italy,Italy,Italy
Call: INNOSUP (H2020-Adhoc-2014-20, 2014)
Start date: 2014-06-01
End date: 2014-12-31
Duration (months): 7.0
Total project cost (EUR): 151726.25
EU funding (EUR): 121381.0
Participants: 12
Project status: CLOSED

The action “Establishing services enhancing the innovation management capacity of SME's in the Enterprise Europe Network" represents an important breakthrough in delivering the EEN services. Until now the EEN consortia partners’ role was mainly catalyzing the SMEs innovation needs with the innovative product, services and processes provided by other companies or research centres, with the aim of fostering their internationalization. Strengthening the target of internationalization, with the New Action, the EEN consortia partners will improve their action providing on site support to SMEs, and becoming a part of the companies for assessing their capacity in the innovation management issues. The SCRIPT consortium as a whole is able to provide the expected services: Key Account Management • Assess SME gaps and needs, • Facilitate the identification and the initial coach-SME interaction to prepare coaching plan, • Support companies in the project management and administration Enhancing SME innovation management capacity • Asses innovation management capacity based on performance, • Action plan implementation.

Keywords: horizon 2020,innovation,technology transfer,internationalisation,market development,assessment,cinema
Enhancing the innovation management capacity of SMEs through the Enterprise Europe Network in Macedonia (INNO EEN-M) (INNO EEN-M)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: North Macedonia,North Macedonia
Call: H2020 2D CONSULTATION EEN (H2020-EEN-SGA2-2017-2018, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 12885.0
EU funding (EUR): 12885.0
Participants: 3
Project status: CLOSED

The general objective of the INNO EEN-M project is to increase the economic returns from innovation and enhanced innovation management capacities of the Macedonian SMEs through offering a standardised set of coaching and innovation management services. The project aims to deliver 26 (twenty-six) 7-day service packages: 20 package services will be provided to SMEs with significant innovation activities and high potential for internationalization and 6 packages for the SME instrument beneficiaries. As the national consortium is responsible for providing services at whole territory of the country, this project will also cover the same area. The services will be delivered by three innovation experts/Key Account Managers (KAM) from UKIM, member of EEN Macedonia. The INNO EEN-M project is highly related to the call for Enterprise Europe Network – Horizon 2020 (2017-2018) and will provide necessary tools, knowledge and experience to the EEN-M for implementation of the specific activities in the context of innovation support. The activities within the project are organized in two work packages: key account management (KAM) for the beneficiaries of the SME instrument and enhancing SME innovation management capacities for innovating SME independently from a specific project. The selection of SMEs will be done based on identified criteria whereas services will be delivered in line with the specific common format with the packages. The team will use the IMP³rove tool as an assessment tool. The KAM will undertake needs analysis/coachcom tool to support SMEs in selection of lead coach. The planned duration of both work packages is 24 months (2017-2018). The services, benefits and experiences from these activities will be part of internal evaluation. The beneficiaries of these activities will be also used for identification of potential needs for training in the future.

Keywords: innovation,smes