Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Mapping and Manipulating Interfacial Charge Transfer in Polymer Nanostructures for Photovoltaic Applications (POLYMAP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-IIF, 2012)
Start date: 2013-06-01
End date: 2015-05-31
Duration (months): 24.0
Total project cost (EUR): 231283.2
EU funding (EUR): 231283.2
Participants: 1
Project status: CLOSED

The goal of the proposal is to develop unique capability and understanding of electroactive materials and their composites, for photovoltaic applications, through the use of emerging nanoscale electrochemical imaging techniques. By combining the strong background and experience of the Fellow (Josh Byers) in materials science, with the impressive facilities, equipment, infrastructure and expertise at the Host Institution, exciting new directions in hybrid photovoltaic materials will developed and explored. Nanostructured organic and inorganic materials are attractive for potential low cost photoelectrochemical energy generation for large scale exploitation. However, these materials are characterized by nanoscale features (typically tens of nm’s), and it has only now become possible to study their electrochemical response on a similar length scale using scanning electrochemical cell microscopy (SECCM), recently invented by the Host Institution. The Fellow will join the Host group to expand the current capabilities to include high resolution photoelectrochemical imaging to study in detail the local (photo)electrochemical processes that occur at the interfaces of electrode materials for next generation photovoltaic devices (eg. dye sensitized solar cells), elucidating the impact of nanoscale morphology and structure on activity. Exploiting the nanoscale dimensions of the SECCM system, new methods for fabricating conjugated polymer nanostructures and composites will also be investigated to develop novel electrode materials. Through a combinatorial approach made possible by SECCM, these materials will be studied in-situ following their fabrication. The results of the project will provide a new view of photovoltaic devices at the nanoscale, ultimately allowing the rational design of improved solar cells. Dissemination to a wide audience is planned to maximise impact and opportunities in Europe.

Keywords: physical chemistry,nanochemistry,electrochemistry,electrochemical imaging,interfaces,photovoltaics,solar cells,conducting polymers,carbon nanotubes,hybrid materials
Mating system and the evolutionary dynamics of hybrid zones (PLANT HYBRIDIZATION)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria
Call:  (FP7-PEOPLE-2012-IIF, 2012)
Start date: 2014-05-01
End date: 2017-09-12
Duration (months): 24.0
Total project cost (EUR): 179137.2
EU funding (EUR): 179137.2
Participants: 1
Project status: CLOSED

Studies that examine the genetic consequences of hybridization and introgression (gene exchange among species) have traditionally considered the genome a single entity. However, the concept of a porous genome suggests differential rates of introgression across the genome as a result of different selective pressures; loci under balancing selection are likely to show high rates of introgression, while loci under divergent selection will resist introgression. The action of these different selective pressures results in variation in both the level of genetic diversity and divergence across the genome. In this project I will focus on the effect of balancing selection at the self-incompatibility locus and compare this to neutral processes (genomic background) and flower colour genes subject to divergent selection. The Antirrhinum system provides a unique opportunity to test these ideas because it has both well-characterized self-incompatibility and flower colour variation. Interestingly, to date, research on hybridization and mating systems have remained largely separate fields, despite the potential importance of mating system for the outcomes of hybridization and patterns of genetic variation across the genome. In this proposal I aim to bring together these distinct fields to assess the role of self-incompatibility in the evolutionary dynamics of hybridization in Antirrhinum by comparing how genetic signatures of selection vary across the genome. To address these questions I will use a combination of molecular genetics, genomics, crossing experiments and ecological approaches. Together, these data will enable a comprehensive examination of the genetic consequences of selection and gene flow across the genome, and whether there is adaptive introgression among species.

Keywords: hybridization,self-incompatibility,balancing selection,divergent selection,mating system,plants,genomics,population genetics,evolutionary biology
Molecular Targets of Uranium in some Aquatic Organisms (MOTAUR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2014-01-02
End date: 2016-01-01
Duration (months): 24.0
Total project cost (EUR): 202405.8
EU funding (EUR): 202405.8
Participants: 1
Project status: CLOSED

Uranium is an important element, massively used in military and civil industry. It is a toxic element and the understanding of the mechanisms of its metabolism, homeostasis and toxicity are of paramount importance. The project aims at the development of a series of novel analytical methods able to identify and quantify the species being products of interaction of uranium with the proteome and metabolome of some aquatic organisms. The organisms include microalgae Fragilariopsis cylindrus and Karenia brevis selected on the basis of reports claiming their unusual toxic metal homeostasis, some shellfish crayfish Orconectes limosus, bivalve Corbicula fluminea known for uranium bioaccumulation, and a model organism zebrafish Danio reiro. The methods to be developed to probe biomolecular targets of uranium include non-denaturating gel electrophoresis with uranium specific laser ablation ICP mass spectrometry imaging followed by canonical proteomics protocols and hydrophilic interaction chromatography with the high-resolution MS detection of uranium complexes present. The maps of the interactions of uranium with biomolecules will be discussed in the context of toxicological data.

Keywords: che uranium,metalloproteome,bioinorganic chemistry,toxicology,icp-ms,separation techniques,aquatic organisms
Gene expression profiling of plant vascular tissue in model and crop species (VASCULAR GENE MAPS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-IOF, 2012)
Start date: 2013-07-01
End date: 2016-06-30
Duration (months): 36.0
Total project cost (EUR): 392423.0
EU funding (EUR): 392423.0
Participants: 1
Project status: CLOSED

Plant vascular meristematic cells are present in the cambium and procambium and divide in a highly ordered manner resulting in cells that differentiate into xylem tissue (responsible for water transport), and phloem tissue (which transport nutrients). Lodging due to breakage of plant stems negatively impacts crop yields, and remains a problem in species such as rice and wheat. Vascular tissue contains cells with woody secondary cell walls that provide much of the plants mechanical strength so modifying developmental processes that lead to vascular specification has the potential to improve yield. Furthermore, the vascular system is responsible for generating the majority of plant biomass. Plant biomass could be utilised in the future to make the next generation of liquid biofuels reducing dependence on fossil fuels. Understanding the events that occur in the vascular meristem may help us to best utilise plants for increased biofuel production. Gene expression maps, where levels of expression of all the genes in the genome in specific cell types have been quantified are extremely useful in identifying genes that control specific processes in the model species. However, there is a lack of similar data for economically important species such as rice. Novel methodologies will be required to generate this expression data as fewer resources are available for these species. This IOF will allow the researcher to learn these methods in Sorghum and tomato in the outgoing phase of the fellowship, prior to applying them in a comparative study of Arabidopsis and rice in the return phase. Individual cell types of the plant vascular system will be isolated using novel methodologies and their RNA will be extracted and sequenced using state-of-the-art techniques. The data will provide an important reference for further research and lead to identification of key genetic components of plant vascular development that could be manipulated to improve grain and biomass yields.

Keywords: l213 systems biology,l202 transcriptomics,l201 genomics - comparative genomics - functional genomics
Eurovision: A History of Europe through Popular Music (EUROVISION)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-09-01
End date: 2015-08-31
Duration (months): 24.0
Total project cost (EUR): 240733.2
EU funding (EUR): 240733.2
Participants: 1
Project status: CLOSED

This project focusses on how popular music has affected and reflected cultural, political and social change in contemporary Europe through the Eurovision Song Contest. Established in 1956, Eurovision is the world’s largest popular music event and one of the most popular television programmes in Europe. As it is based on national entries, Eurovision provides case studies of how countries have imagined and branded themselves for a pan-European audience, while its voting results have been used as a measure of how different national publics perceive each other. Furthermore, political issues such as minority rights have been highlighted there through the performances of members of ethnic and sexual minorities, while other entries have taken environmental and peace causes as their theme. This project will use Eurovision to examine the major transnational themes that have defined contemporary European history: nationalism, European integration, democracy, prosperity, war, sexuality and youth. It will analyse these themes through the cultural and political relationship of Eurovision entries to them as expressed in the latter’s lyrics, music, costumes and choreography, as well as through a comparative examination of the public debates across Europe that have accompanied the contest. The project will address how countries have used the contest to define their identities within a European context, be it to assert their national distinctiveness, highlight political issues or affirm their “Europeanness.” It will also examine how “Europe” and “Europeanness” have been defined through Eurovision in cultural, political and social terms, and how the contest has defined and spread cultural, political and social values across the continent. Through the project I will produce the first ever academic monograph on Eurovision, as well as articles for publication in leading historical journals and papers for presentation at international conferences.

Keywords: s113 communication networks - media - information society,s309 music and musicology - history of music,s311 cultural studies - cultural diversity,s405 modern and contemporary history
Molecular pathogenesis of a novel thyroid hormone resistance syndrome caused by mutations in thyroid receptor alpha 1 (TRACTION)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-05-04
End date: 2014-05-03
Duration (months): 12.0
Total project cost (EUR): 115641.6
EU funding (EUR): 115641.6
Participants: 1
Project status: CLOSED

Thyroid hormone (TH) is crucial for the normal development and metabolism of all tissues. The actions of the bioactive T3 are mediated by binding to its nuclear receptors (TRs), of which TRa1 and TRb1 are the main isoforms. It is known for decades that mutations in TRb1 result in resistance to TH, among others characterized by goiter and tachycardia, and abnormal TH levels. Ever since its characterization in 1987, investigators have searched for patients with mutations in TRa1. However, very recently the host and applicant’s laboratory independently discovered the first patients with inactivating mutations in TRa1. These patients show growth retardation, delayed bone, motor and mental development as well as abnormal TH levels. The patients display remarkable differences in neurological, bone and biochemical phenotype. Interestingly, all mutants are located within exon 9, which encodes a domain important for ligand binding and interaction with co-activator and co-repressor proteins. It is likely that mutant-specific properties underlie the differences in clinical phenotype. The aim of this project is to unravel the molecular mechanisms leading to the clinical phenotype of patients with TRa1 mutations. The key objectives are: (i) to study direct effects of mutations in a reporter assay; (ii) to detail consequences of mutations on downstream target genes; (iii) to identify alterations in the interaction of the receptor mutants with cofactor proteins and (iv) to establish a genotype-phenotype relationship. Using an integrative approach with well-established and advanced techniques, this scientifically fascinating project will certainly deepen our understanding of the role of TRa1 in health and disease. The combination of the longstanding expertise of resistance to TH in the host laboratory together with my studies and experience concerning all aspects of cellular TH regulation will promise the success of this project.

Keywords: l101 molecular biology and interactions,l201 genomics - comparative genomics - functional genomics,l403 endocrinology
Algorithmic Game Theory: Foundations and New Directions (ADVANCE-AGT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2012-IOF, 2012)
Start date: 2013-08-01
End date: 2016-07-31
Duration (months): 36.0
Total project cost (EUR): 351421.0
EU funding (EUR): 351421.0
Participants: 1
Project status: CLOSED

The last decade has seen a surprisingly rich interplay between economics, computer science, and game theory, and a new discipline, algorithmic game theory, has evolved. I propose to conduct research on subjects that will advance state of art in this evolving discipline. First, study mechanisms for players with non-standard utility structures, better describing the actual way that players behave in reality. Second, make advancement in truthful scheduling, a core theoretical model with many important open problems whose solution is key to advancing the entire field. Third, game theoretic aspects of social networks. As social networks are key in today's reality, research on this topic will broaden the horizons of our scientific field. I propose to conduct this research at UC Berkeley, under the supervision of Prof. Christos Papadimitriou, one of the founding fathers of algorithmic game theory. Such a training period at current time will help me to gain a more senior position in my community. At the end of the period I will return to Technion where I am a faculty member, where I will head a research group on this subject. The knowledge that I will accumulate at Berkeley is essential to the successful formation of the group.

Keywords: m104 algorithms and complexity,algorithmic game theory
Low-dimensional and Non-autonomous Dynamics (LDNAD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-03-01
End date: 2016-10-05
Duration (months): 24.0
Total project cost (EUR): 221606.4
EU funding (EUR): 221606.4
Participants: 1
Project status: CLOSED

This research project aims at making significant contributions to the bifurcation theory for non-autonomous (i.e., forced or random) dynamical systems. Dynamical systems is a very active research field, with a plethora of applications in other areas of mathematics as well as the applied sciences. Many dynamical systems arising from real-world applications are forced (non-autonomous), that is, driven by some external system or noise. In recent decades, there has been steadily growing interest in the theory of non-autonomous dynamical systems, which was mainly motivated by applications in physics, biology, engineering, chemistry, economics, ecology and other disciplines. Mathematical modelling is used extensively in engineering, and the natural and social sciences and typically gives rise to complicated dynamical systems depending on one or several parameters. Fluctuations in these physical parameters can lead to qualitative changes in the behaviour of the system (when a parameter reaches a critical value), referred to as a bifurcation or critical transition, where a sudden change in the dynamics is observed. Bifurcations and critical transitions occur in a wide variety of applications including climate change, medicine, and economics, and the understanding of the dynamical behaviour of systems near bifurcation points plays an important role to control and attenuate the expected consequences. The main aim of this research project, is to develop insights and tools in order to complement the study of non-autonomous bifurcation theory. The proposal contains the following research directions: 1. The development of a non-autonomous bifurcation theory for deterministic dynamical systems. 2. The development of a general qualitative theory for forced monotone interval maps with transitive forcing. 3. The development of a bifurcation theory for random dynamical systems. 4. The description and rigorous analysis of the stochastic Hopf bifurcation.

Keywords: m111 ode and dynamical systems
Palaeolithic Populations in Armenia and Turkey: Expanding Archaeological Understanding (PLATEAU)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Türkiye
Call:  (FP7-PEOPLE-2012-IIF, 2012)
Start date: 2013-09-15
End date: 2015-09-14
Duration (months): 24.0
Total project cost (EUR): 166336.2
EU funding (EUR): 166336.2
Participants: 1
Project status: CLOSED

The proposed multi-disciplinary project investigates hominin behavior during the Middle Pleistocene in Turkey and Armenia in terms of regional hominin behavior patterns, population dynamics, and dispersals. Based on available fossil data, recent studies on Eurasian hominin dispersals hypothesize ‘source’ areas for populations, including the Balkans, the Levant, and Central Asia. Lying geographically between these areas, Anatolia and the southern Caucasus are two crucial regions for understanding hominin population dynamics and dispersals. However, due to biased research intensity the regions still represent knowledge gaps in the Palaeolithic database. The main objective of the proposed research is to generate new archaeological data for the Middle Palaeolithic in Turkey and Armenia. The research seeks to integrate regional archaeological data into theories on hominin population dynamics. Preliminary archaeological data from upland open-air sites in Turkey and Armenia suggest regionally distinct patterns in technology and land use, and may indicate complex population dynamics, involving geographically isolated populations and local extinctions. In the proposed research, regionally distinct patterns in technology and land use are viewed in terms of ‘culturally mediated’ structured metapopulations. Research methods include: analyzing artifact techno-typology in two comparative regions of Turkey and Armenia; experimental archaeology; mapping and excavating archaeological deposits; studying archaeological site formation using field and laboratory methods; chronometric dating and sampling of archaeological deposits using a variety of techniques. Data generated in this project will aid comparison with more intensely studied regions of Eurasia, will refine theories on hominin population dynamics, and expand knowledge of human evolution. The applicant will transfer knowledge to the ERA through teaching, collaborative laboratory and fieldwork, and outreach activities.

Keywords: s401 archaeology - archaeometry - landscape archaeology,s402 prehistory and protohistory,middle palaeolithic,lithic technology,v201 geology - tectonics - volcanology,geoarchaeology