Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
IMmersive digitisation: uPcycling cULtural heritage towards new reviving StratEgies (IMPULSE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Poland,Belgium,Italy,Malta,Germany,Greece
Call: Re-visiting the digitisation of cultural heritage: What, how and why? (HORIZON-CL2-2023-HERITAGE-01, 2023)
Start date: 2024-02-01
End date: 2027-01-31
Duration (months): 36.0
Total project cost (EUR): 3393717.5
EU funding (EUR): 3393717.5
Participants: 11
Project status: SIGNED

Digital technologies are also playing a key role in the sustainability transformation; therefore, IMPULSE applies a comprehensive approach to tackling some of the major pressing gaps in the European cultural heritage digitization processes. In doing so, IMPULSE will develop ground-breaking, comprehensive solutions and methods for digitization processes and accessibility of digital cultural heritage collections, that will enable their innovative (re)use, solve challenges related to the interoperability of platforms and facilitate the availability of existing digitized cultural heritage content in novel contexts like the Metaverse while creating innovative standardization procedures and adapting legal frameworks to contemporary transformations and creative processes in and for education, arts, and CCSI. IMPULSE will foster solutions that extend the range, and consequently the quantity, of artifacts and objects, that can be displayed through using XR to recreate objects, making collections more virtually accessible in order to enable original uses of digital cultural heritage archives to create diverse, and layered narratives, for the wider demographic audience and underrepresented communities, empowering them to engage more deeply with the topics and themes on display, also through artistic (visual artists and dancers) performance through IMPULSE’s pilots and prototypes. IMPULSE will also enable connections and encounters among researchers, artists, cultural heritage practitioners, CCSIs, entrepreneurs, local institutions, companies, and other relevant stakeholders, through effective engagement such as IMPULSE Community of Practice, and appropriate tools and channels such as IMPULSE Hackathon and Acceleration & Mentoring Hub in order to facilitate effective dialogue, co-creation, and capacity building in immersive digitization.

Keywords: digitization cultural heritage metaverse interoperability participation re use storytelling intelectual property
Topology in Symplectic, Contact, Low Dimensions and Singularities (Top-SCoLDS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: Hungary,United Kingdom,France,Germany,Austria,United States,Italy
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 3696487.56
EU funding (EUR): 3696487.56
Participants: 9
Project status: SIGNED

It is our natural desire to understand the structure of the space-time that we live in. This can be described in mathematical terms as a 4-dimensional space, or "manifold". Surprisingly, dimension 4 is the most mysterious and elusive of all dimensions. In dimensions both lower and higher than 4, we have a rather clear picture about questions related to continuity and differentiability properties. By contrast, dimension 4 is highly irregular in many significant aspects, and, despite several breakthrough results in the past fifty years, we still do not have a panoramic view of the landscape of 4-dimensional spaces. The doctoral network Top-SCoLDS will prepare a new generation of researchers to answer deep questions related to 4-dimensional manifolds. The subject can be approached from many perspectives, including algebraic and symplectic-contact geometry, geometric topology, knot theory, partial differential equations, and artificial intelligence. Top-SCoLDS will take a diversified approach to questions about 4-dimensional manifolds, leveraging the members' complementary expertise. Top-SCoLDS will bring together world-leading experts in these fields, who will join their efforts to provide a comprehensive educational path for 12 PhD students. The students will be exposed to diverse tools and techniques to attack cutting-edge research questions on 4-manifolds, giving them a wide perspective on the subject and the opportunity to thrive in this active research area. The PhD students will benefit from research, education, and complementary skills training. They will receive training from world leaders in the theory and application of machine learning, AI, and topological data analysis, and from a wide range of non-academic and industrial partners. This will enable these students to innovate, collaborate, and become leading professionals in mathematics, and will ensure that they can apply their skills beyond the academic context and excel in the industrial sector too.

Keywords: singularity,low dimensional topology,symplectic topology,contact topology,heegaard floer invariants,smooth four manifolds,lattice homology
Designing a powerful drone-based sampling device to monitor the released toxic volatile organic compounds caused by forest fires (VOCfireDRONE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 214344.72
EU funding (EUR): 214344.72
Participants: 1
Project status: SIGNED

Climate change is one of the most pressing environmental challenges of our time that has led to a dramatic escalation in the frequency and intensity of forest fires. As global warming continues to increase, addressing the challenge to investigate their effects has never been more urgent. A major concern that arises during a forest fire is the rapid and intense release of hazardous volatile organic compounds (VOCs) into the environment that can be toxic and potentially carcinogenic. These hazardous compounds continue to be emitted even after the extinguishment of a forest fire, while new toxic compounds can be also formed. Focusing on minimizing their adverse effects on human health, the comprehensive monitoring of VOCs release during and after a forest fire is of utmost importance. To be able to obtain an as realistic and comprehensive estimate as possible on the chemical identity, concentration, and temporal profile of hazardous compounds, it is imperative to do the sampling as close as possible to the point of emission, which indicates the demand for a remote-controlled drone-sampling device. The overall aim of this project is thus to develop a powerful drone sampling system that can be used for the monitoring of toxic VOCs during and after a forest fire, focusing on decreasing the risks that occur from human exposure to these compounds. The drone will be equipped with a novel type of sorptive extraction samplers and laboratory analysis will be performed using one- and comprehensive two-dimensional gas chromatography-mass spectrometry to elucidate the extremely complex pattern of VOCs being produced by these events. This aims to provide a comprehensive understanding of the damage caused to first responders and the exposed population due to the emission of toxic and harmful compounds during forest fires.

Keywords: separation science,climate change,wildfires,environmental analysis,sample preparation,sorptive extraction techniques,gas chromatography
Dual circuit flow battery for hydrogen and value added chemical production (DualFlow)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Finland,Denmark,Ireland,United Kingdom
Call: Novel routes to green hydrogen production (HORIZON-EIC-2021-PATHFINDERCHALLENGES-01, 2021)
Start date: 2022-10-01
End date: 2026-09-30
Duration (months): 48.0
Total project cost (EUR): 2835282.5
EU funding (EUR): 2835282.5
Participants: 8
Project status: SIGNED

DualFlow develops a radically new energy conversion and storage concept that combines water electrolysis, battery storage and co-production of decarbonized chemicals into one single hybrid technology using water soluble redox mediators as energy transfer vectors. The system can be operated for electricity storage or for energy conversion to hydrogen and value added chemicals. During energy storage operation, the system works as a conventional stationary flow battery. The energy conversion starts when the battery is full but there is abundant inexpensive green electricity available. Now the battery is chemically discharged in a mediated electrolysis to produce hydrogen and value added chemicals. The energy conversion is realized by pumping charged battery electrolytes through reactors. For hydrogen production, reactor is filled with catalytic particles to catalyze electron transfer and hydrogen evolution. For value added chemical production the reactor consists of biphasic system where charged electrolyte oxidizes chemicals in an organic phase. The reaction products are then extracted into the organic phase. The energy conversion operation requires only reactors and catalyst for hydrogen evolution, indicating that the additive costs of the dual circuit is minimal. The concept results in flexible system capable of both energy storage and energy conversion to hydrogen. We strongly believe that this concept offers possibilities to produce inexpensive hydrogen, in a flexible manner without utilizing any critical raw materials.

Keywords: flow battery,mediated electrolysis,electrosynthesis
Transitions in Rubble-pile Asteroid Chaotic Environment and granular Structures (TRACES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 1499750.0
EU funding (EUR): 1499750.0
Participants: 1
Project status: SIGNED

We are now living exciting times for asteroid exploration. The increasing availability of in-situ observation data, providing unprecedented level of detail, makes the study of asteroids an exciting and living frontier. Asteroids are rubble piles, i.e., gravitational aggregates of loosely consolidated material. However, no direct measurements of asteroids’ interior exist and little is known about the mechanisms governing their formation and evolution. Not only limited by a lack of data, the understanding of asteroids’ properties is challenged at a fundamental level by their rubble-pile nature. This makes their dynamics subject to the laws of granular mechanics, one of the major unsolved problems in physics. TRACES enables a new paradigm for the characterization of granular systems in asteroid-related scenarios. The ambition is to demonstrate that the macroscopic behaviour of granular media in asteroid environment can be inferred from local properties of the grain. The methodology lays its foundation on a cutting-edge simulation tool, able to resolve the dynamics of grains to particle-scale precision, and a theoretical framework, able to decode the chaotic nature of particle-scale dynamics. TRACES’ hypothesis is validated through theoretical, numerical and experimental work. The ability of the methodology to characterize and identify transitions between dynamical regimes of granular media, is tested gradually, for increasing levels of realism, ranging between proof-of-concept, laboratory scenarios involving experiments in vacuum/low-g, and full-scale scenarios involving asteroid mission data. If successful, TRACES will enable the characterization of surface and internal properties of asteroids with limited observation data. This will play a crucial role to enable the next breakthrough in asteroid science, as well as efficient/cost-effective design of the next generation of space missions to explore and exploit asteroids, including planetary defence applications.

Keywords: asteroids rubble pile dynamics asteroid surfaces and interiors n body granular simulations nonlinear dynamical systems
Innovative precast panels for Integrated SEismic and Energy upgrading of existing buildings envelopes (i-SeePanel)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Portugal,Belgium
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-01-02
End date: 2026-01-01
Duration (months): 24.0
Total project cost (EUR): 156778.56
EU funding (EUR): 156778.56
Participants: 2
Project status: SIGNED

There is an urgent socio-economic and environmental need in Europe for sustainable and effective solutions for integrated seismic and energy upgrading of existing buildings as recently adopted by the Green Deal-Renovation policy. Although the field of integrated seismic and energy upgrading has received great attention in the academic community in the last five years, further research is required towards faster, and eco-friendly integrated retrofitting solutions. This project, i-SeePanel, goes several steps beyond the state-of-the-art which still lacks of the real applications of integrated retrofitting solutions, via the development of Innovative externally bonded precast panels, in accordance with Life Cycle Thinking (LCT) principles, for integrated seismic and energy upgrading of existing buildings envelopes. The proposed precast panels combine the promising seismic strengthening solution TRM (composite material consisting of fibre-textiles reinforcement embedded into an inorganic matrix) with insulation materials providing several advantages compared to cast-in-place solutions by guarantying the effectiveness of the solution (quality-controlled) with high aesthetic and geometry adaptability potentials, and by reducing the time of the intervention, the inconveniences for the inhabitants and the labor effort due to simplifier installation procedure. The research activities of this project include the experimental work for the production and characterization of the matrix material and of the precast panel, pilot laboratory applications on full-scale masonry-infilled RC frames, and the developing design guidelines for proposed applications. The outcomes obtained from this project will encourage the renovation of existing buildings and will aid the authorities in funding upgrading interventions, while at the same time the use of the proposed solution will be beneficial to enhance the resilience and the sustainability of existing building stock.

Keywords: integrated retrofitting,precast panels,textile reinforced mortar trm,resilience of build environment
Migratory 1,n-fluoroalkylcarboxylation of non-activated alkenes via dual photoredox/ Nickel catalysis (FLUOR-DIOX)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: SIGNED

Catalytic chain-walking reactions have recently emerged as a powerful tool for efficiently introducing functionalities at remote sp3 C–H sites within alkyl side chains. Nevertheless, substantial challenges remain when forging multiple C–C bonds while maintaining a predictable site-selectivity profile in chain-walking scenarios, particularly by controlling both regioselectivity and enantioselectivity. This project will explore the ability to introduce both fluorinated fragments and CO2 at an unsaturated hydrocarbon via dual photoredox/nickel catalysis with a predictable selectivity pattern. Such a transformation constitutes an unrecognized opportunity in chain-walking scenarios for introducing, at will, fluorinated fragments and carboxylic acid functions in a dual, yet modular, site-selective manner. Aimed at exploring the full potential of such an approach for accessing added-value fluoroalkyl carboxylic acids, a new class of C2-symmetric ligands will be rationally designed and developed. The impact that this technique might have in industrial endeavors will be assessed in collaboration with industrial partners of the host group by its application in late-stage modification of advanced intermediates, radiolabeling, and the synthesis of MRI probes.

Keywords: nickel catalysis,chain walking,carbon dioxide fixation,difunctionalization,c h functionalization
Uncovering New Worlds: Enhancing Optical Interferometry to detect reflected light exoplanet (PLANETES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: France,Germany
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2025-04-01
End date: 2030-03-31
Duration (months): 60.0
Total project cost (EUR): 3490464.0
EU funding (EUR): 3490464.0
Participants: 3
Project status: SIGNED

The project's objective is to develop PLANETES, a pioneering ground-based interferometric system, engineered to transform the study of exoplanet atmospheres through high-contrast observations. The primary goal is to significantly enhance the dynamic range of optical interferometry, enabling the observation of exoplanets via their reflected stellar light. Other objectives include investigating the atmospheric composition of known exoplanets and identifying potential protoplanets. The strategy involves setting up a laboratory bench to scrutinize and address the current limitations observed with the GRAVITY instrument at the VLTI. These enhancements will then be deployed at the Paranal Observatory to examine the multitude of exoplanets anticipated from forthcoming Gaia spacecraft data releases. PLANETES is set to be the first ground-based instrument capable of observing exoplanets via reflected light, offering a contrast range of 10 million at less than 100 milliarcsecond. It will significantly surpass the detection and characterization capabilities of current ground-based instruments. In addition to fostering significant advancements in exoplanetary research, this project encompasses the development of a ground-breaking 4-million-pixel infrared camera. This device, equipped with a very low read noise and low dark current detector, will unveil new potential in high-contrast astronomical instrumentation. For the first time, it will allow to simultaneously have a good spectral resolution and high sensitivity, representing a significant leap in the field. This pioneering technology will set the stage for future instruments, yielding broad advantages to the scientific community at large.

Keywords: long baseline optical interferometry direct detection of exoplanets
Circular RNAs to reverse pathological remodelling of the injured heart (REVERSE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 2499375.0
EU funding (EUR): 2499375.0
Participants: 1
Project status: SIGNED

Heart failure (HF) is a most common cause of mortality with currently >60 million of affected patients. Numbers will increase due to socioeconomic factors and as a result of the current COVID-19 pandemic. A major underlying cause of HF are cardiac remodelling processes at the molecular, cellular and tissue level. We will here focus on noncoding circular RNAs (circRNA) involved in two distinct forms of cardiac injury, chemotherapy-induced cardiotoxicity and SARS-CoV-2-infection, where currently no specific treatment strategies are available to reverse disease pathology. First proof-of-concept studies targeting the cardiac remodelling process by noncoding RNA modulation have been pioneered by us and were recently tested in a world-wide first clinical phase 1b study in HF patients. Within the family of non-coding RNAs, circRNAs are stable and species-conserved and thus ideal drug targets. We discovered multiple molecular circRNA signatures during remodelling of cardiac cells and tissues from mice and patients. We now aim to lift our research to its next inflection point with the following steps and interconnected objectives: a) discover key functional circular RNAs involved in remodelling processes by functional CRISPR-Cas library screening; b) validate circRNAs by manipulating human living beating myocardial tissue, c) explore their mode of action; and d) perform targeted cardiac delivery approaches of selected candidates in both chemotherapy-induced cardiotoxicity and SARS-CoV-2-induced cardiac disease models. A combination of bioinformatic, molecular and physiology-based methods, unique established noncoding RNA drug discovery pipelines, availability of modern S3-safety labs, large clinical biobanks and (fresh) human cardiac tissue for slicing preparations form the basis for a successful strategy. REVERSE aims to discover fundamentally new therapeutic entry points for two forms of cardiac injuries, where currently no disease-specific treatments are available.

Keywords: circular rnas noncoding rnas