Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Frustrated Power: Proton-Electrolyte-Membrane Hydrogen Fuel Cells Catalyzed by Frustrated Lewis Pairs (FLPower)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2014-12-01
End date: 2015-11-30
Duration (months): 12.0
Total project cost (EUR): 149533.75
EU funding (EUR): 149533.75
Participants: 1
Project status: CLOSED

Despite H2 fuel cell technology pre-dating the internal combustion engine the technology has not progressed much in 100 years. All hydrogen fuel cells use precious (rare and expensive) metal catalysts to oxidise H2, and reduce O2, such as Pt. These “precious” metals currently prevent the widespread use of fuel cells. The US Department of Energy has set a target of 0.125g of Pt / kW energy produced from fuel cells, and a total cost of $30 /kW. The current record stands at 0.2 g Pt/kW and a cost of $36/kW. The automotive industry requires the current Pt content of fuel cells to be reduced by 1/3 to become economically viable. Pt is a major cost component and is clearly a problem. This project develops a way to reduce Pt content of fuel cells by half – falling well below DoE targets and those of the automotive industry. We do this by replacing rare and expensive Pt metal used to oxidize H2 on 1 side of the fuel cell with molecular catalysts made of B, C, Cl, and F elements – cheap and abundant materials! The molecular catalysts that we have developed form “frustrated Lewis pairs” (FLP). A suitable Lewis acid and a Lewis base when combined form an FLP which can be used to heterolytically split H2. The resulting Lewis acid hydride is then oxidized at a carbon electrode, and the energetic driving force required to oxidise H2 into 2 H+ and 2e– is greatly reduced by as much as 610 mV (equivalent to catalyzing the reaction by 118 kJ mol-1) without using any Pt. This proposal seeks to build on this pioneering work. We have found that FLP reactions can occur at very electron deficient Lewis acids without needing a Lewis base! Instead we can use a common organic solvent, tetrahydrofuran, as the Lewis base, and form water tolerant Lewis acid catalysts, that cleave hydrogen in seconds on the same timescale as electrooxidation. This fund will allow us to develop aqueous FLP arylborane electrocatalysts and build prototype “frustrated fuel cells” as clean, cheap, energy devices.

Keywords: frustrated lewis pairs,electrocatalysis,hydrogen,fuel cells,batteries,electrochemistry,energy
Inclusive Education for an Inclusive Europe: Examining Social Interactions, Dynamics and Friendship Networks of Students in Mainstream Primary Schools (IE2)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United States,United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2018-08-31
Duration (months): 36.0
Total project cost (EUR): 251857.8
EU funding (EUR): 251857.8
Participants: 2
Project status: CLOSED

The overarching research aim of this project is to examine the social interactions, dynamics and friendship networks of all students, with an emphasis on those identified as having special educational needs, in mainstream primary schools. The IE2 project strives to understand how inclusive education is being implemented across three countries (US, UK, Cyprus) and contribute to the debate on how to create a more inclusive European society by providing rigorous research evidence and recommendations. The project sets out to achieve three main objectives. First, to develop an innovative and interdisciplinary methodology to understand the social interactions, peer relationships and friendships with the combination of advanced social network analysis and ethnographic methods. Second, to establish a social network analysis toolkit for schools to enable practitioners understand the social dynamics within their settings. Third, to develop a platform for visualizing large datasets within social sciences and humanities. It is anticipated that the project will generate a significant impact on both the educational and social sciences and the researcher in terms of reaching a higher position of professional maturity. This is a project that is innovative and interdisciplinary as it breaks the boundaries between social sciences and humanities and computational studies, mathematics and statistics.

Keywords: data visualization,social network analysis,social interaction,social inclusion
environmentAL Toxicity chEmical mixtuRes through aN innovative platform based on aged cardiac tissue model (ALTERNATIVE)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Spain,Italy,Italy,Italy,Italy,Bulgaria,Belgium,France,Netherlands
Call: Fostering regulatory science to address combined exposures to industrial chemicals and pharmaceuticals: from science to evidence-based policies (H2020-LC-GD-2020-3, 2020)
Start date: 2021-10-01
End date: 2024-09-30
Duration (months): 36.0
Total project cost (EUR): 5499757.25
EU funding (EUR): 5499757.25
Participants: 11
Project status: SIGNED

ALTERNATIVE will develop an innovative platform able to detect the cardiotoxicity of chemicals and their bio-transformation products. The novel platform will enable regulators and industry to identify, quantify and prevent cardiotoxic co-exposures to industrial chemicals and pharmaceuticals in a cost-effective way. ALTERNATIVE will particularly focus on cardiotoxic effects on older people, which is of high relevance in view of the ageing EU population and the high spread of cardiovascular diseases. The platform will consist of a three-dimensional tissue engineering in-vitro model mimicking the human cardiac tissue, coupled with a reliable, high-throughput monitoring system based on multi-omics analyses, and integrated into a Machine Learning (ML) risk assessment tool. In addition, ALTERNATIVE will modify the tissue model to reproduce the aged myocardial tissue and elucidate the adverse effects of chemicals on older people. ALTERNATIVE?s proof-of-concept validation will be performed on well-known mixtures of pollutants, affecting different environmental compartments, and selected via epidemiological, toxicological and modelling expertise. ALTERNATIVE will also provide systematic reviews of high-quality epidemiological studies to support integrated in vitro and in silico data, giving a more robust basis for regulatory decisions. The ALTERNATIVE platform will be an innovative tool for complying with the current regulation associated with the assessment of chemical compounds. It will be a new instrument to evaluate unpredictable toxicity due to synergistic effects of different chemicals, additionally worsened by the human ageing process. By introducing an in vitro cardiac system and ML models, ALTERNATIVE will provide a platform able to refine, reduce and replace the need for animal testing, providing close-to-real scenario information on toxicity and achieving a significant reduction of the associated direct and indirect costs.

Keywords: cardiac 3d tissue models,proteomics,metabolomics,transcriptomics,in silico models,chemical mixtures toxicity,regulatory uptake
Challenging the ICT Patent Framework for Responsible Innovation (CIFRA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Germany
Call: Enabling responsible ICT-related research and innovation (H2020-ICT-2016-1, 2016)
Start date: 2016-11-01
End date: 2017-11-30
Duration (months): 13.0
Total project cost (EUR): 351952.5
EU funding (EUR): 351952.5
Participants: 4
Project status: CLOSED

The aim of the project is to provide a structured review of the role of the Patent System on the innovation process and how it impacts the social development with specific focus on the particularities of ICT research and innovation. The project will identify and thoroughly characterize the imperfections of the current system and propose alternatives that provide better alignment between ICT Research & Innovation, human needs and societal expectations. Therefore the project will propose alternative framings that result in a more effective and efficient tool for collaborative innovation and real technical and social development. These alternative framings may comprise suggestions to adapt existing tools (such as the patent system), or defining new mechanisms (such as new innovative licensing schemes). An specific area of study will be the open source software model, which currently seems to work well for software development, to assess its pros and cons as a collaborative innovation scheme and to what extent the advantages of the open source ‘philosophy’ could be extrapolated to the patent system. The analysis and outcomes of the project will not just be theoretical but, whenever applicable, it will be based on a thorough data analysis of the patent landscape in the ICT sector.

Keywords: patents,responsible reasearch and innovation,open source
In vivo pharmacogenetic investigation of 5-HT mechanisms in emotional learning (5HT-DREADD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-07-01
End date: 2018-06-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Emotional health and well-being is widely accepted to be crucial for healthy life and the success of societies. Anxiety and depression are two common and debilitating emotional disorders, with highly negative social and financial implications. Serotonin (5-hydroxytryptamine; 5-HT) is thought to be critical to the healthy mood regulation and strongly implicated in the vulnerability to anxiety and depression. Importantly, accumulating evidence suggests that 5-HT’s main influence is upon emotional learning rather than on mood directly. The objective of this proposal is to determine the neural mechanisms through which changes in 5-HT levels, within defined neuronal circuits, affect learning and memory for aversive emotional experiences. New pharmacogenetic techniques will be developed that allow the selective triggering of 5-HT neuron activation and then inhibition in the same animal. We will use this technology to stimulate or inhibit 5-HT release in the basolateral amygdala, a brain area that is crucial for aversive learning, whilst an animal is engaged in an emotional processing task. Through this we will learn how 5-HT modulates neuronal activity in the amygdala at critical time-points during the encoding and retrieval of aversive memories. The results from these studies will provide entirely new insights into how 5-HT modulates amygdala information processing and aversive learning. Understanding how 5-HT affects emotional learning will ultimately lead to a deeper understanding of healthy mood states and the biological mechanisms underlying vulnerability to disorders such as anxiety and depression.

Keywords: dreadds,kord,anxiety
COmbined hybrid Solution of Multiple HYdrogen Compressors for decentralised energy storage and refuelling stations (COSMHYC)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Research and Innovation actions
Partnership: FCH2 (Art-187)
Countries involved: Germany,Germany,Germany,France,Denmark
Call: Development of innovative hydrogen compressor technology for small scale decentralized applications for hydrogen refuelling or storage (H2020-JTI-FCH-2016-1, 2016)
Start date: 2017-01-01
End date: 2021-02-28
Duration (months): 50.0
Total project cost (EUR): 2496830.0
EU funding (EUR): 2496830.0
Participants: 6
Project status: CLOSED

The COSMHYC project aims at answering the needs identified by the MAWP of the FCH2 JU of increasing energy efficiency of hydrogen production while reducing operating and capital costs, in order to make hydrogen a competitive fuel for transport applications. COSMHYC will develop and test an innovative compression solution from 1 to 1000 based on a hybrid concept, combining a conventional compressor with an innovative compression technology. The aim is to reduce the overall compression costs, by reducing investments costs down to less than 2000 €/(kg*day), reducing energy consumption by optimizing the interactions between both compression technologies. Maintenance will be reduced to <50% compared to mechanical compressors and life time will be improved, by decreasing the degradation down to 1% per year, thanks to mechanical adjustments and the implementation of appropriate remote control devices and corrective algorithms. In addition, the system will be significantly less noisy than a mechanical compressor (less than 60 dB at 5 meters). LBST will perform an analysis of the market requirements and define the main critical parameters, which will be used as an input for the research and development activities. MAHYTEC, NEL and EIFER will develop and test both compressors, with a focus on thermal integration. The partners will jointly install, connect and test both components of the new compressor solution in two sites. At each stage of the developments and tests, the results will be used to perform a technical economic assessment of the solution compared to competitors with LBST. In parallel, Steinbeis 2i will accompany the partners in organizing and managing the communication around the project, disseminating the results and preparing their exploitation.

Keywords: hydrogen refuelling,hydrogen mobility,diaphragm compressor,energy efficiency,renewable energies,hydrogen production,decentralized energy storage,high pressure
Towards an e-infrastructure Roadmap for Open Science in Agriculture (e-ROSA)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Support and infrastructures
Action type: Coordination and support actions
Countries involved: Greece,France,Netherlands
Call: Support to policies and international cooperation for e-infrastructures (H2020-INFRASUPP-2016-1, 2016)
Start date: 2017-01-01
End date: 2018-06-30
Duration (months): 18.0
Total project cost (EUR): 399056.25
EU funding (EUR): 399056.25
Participants: 3
Project status: CLOSED

The strategic goal of e-ROSA is to provide guidance to EU policies by designing and laying the groundwork for a long-term programme aiming at achieving an e-infrastructure for open science in agriculture that would position Europe as a major global player at the forefront of research and innovation in this area. Through a foresight approach, the project will build a shared vision of a future sustainable e-infrastructure for research and education in agriculture and make it operable through pragmatic recommendations that will be reflected in a common roadmap. This will be achieved through a process of co-design, involving mainly research and education communities but also practitioners and EU policy makers, and will build on the existing projects, networks, international alliances or initiatives that the project will systematically map and integrate in the analysis of grand challenges ahead and the identification of priorities and solutions towards an open, digital and data-intensive science in agriculture.

Keywords: open science,agriculture,food,e infrastructure,research and education,roadmap,vision,foresight,societal challenges
Positive and Negative Asymmetry in Intergroup Contact: Its Impact on Linguistic Forms of Communication and Physiological Responses (PNAIC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2020-06-05
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

While positive intergroup contact has been shown to reduce discrimination, negative contact has the potential to worsen intergroup relationships. Yet little is known about the interaction between positive and negative contact, whereas people are frequently exposed to both types of contact. This research project will provide an original and comprehensive investigation into the positive-negative asymmetry of intergroup contact (PNAIC) effect, to understand whether positive contact exerts stronger effects than negative contact, improving social integration. The net impact and the possible consequences of a mix of both positive and negative intergroup contact will be examined at interpersonal and contextual levels. A series of studies will systematically test three plausible outcomes: buffering (i.e., positive contact attenuates detrimental effects of negative contact), facilitation (i.e., negative contact augments the impact of positive contact), and poisoning (i.e., negative contact reduces the impact of positive contact) effects. Using one diary study, one longitudinal survey and two experimental studies, the research project will consider also key moderating processes that help explain the joint impact of positive and negative contact on intergroup discrimination. The phenomenon will be analyzed on linguistic and physiologic outcomes, as reliable and unobtrusive measures of discrimination. The unintentional use of language to perpetrate outgroup discrimination and the unintended different physiologic responses to ingroup and outgroup faces will provide insight into the challenge of contact not just in temporary discriminatory reactions but in future interactions. Across the studies, the positive-negative contact asymmetry effect will be investigated towards groups that are both discriminated against and perceived as threatening, such as immigrants in Europe today. This will be done among majority and minority group members, using both direct and vicarious contact.

Keywords: intergroup contact,intergroup discrimination,linguistic discrimination,social neuroscience of prejudice
Realistic Assessment of Historical Masonry Bridges under Extreme Environmental Actions (RAMBEA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-07-03
End date: 2021-11-30
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

The RAMBEA project will develop a novel computational strategy for accurate and efficient simulations of historical masonry bridges subject to extreme environmental actions, including loadings induced by earthquakes and flooding. The aim is to provide a comprehensive tool for realistic assessment with the potential of transforming current practice related to strengthening of critical assets, contributing to an increased resilience of the built environment and the preservation of important elements of the architectural heritage, thus responding to the safety and socio-economic needs highlighted in Horizon 2020. Old masonry bridges still play a critical role within the European transportation system. Moreover, they belong to the architectural heritage representing a valuable expression of past construction technology. Many of these structures are located in seismic regions and in areas subject to floods and hydrogeological instability which have been aggravated by climate change. Thus they can be exposed to extreme environmental actions which may potentially lead to bridge failure causing significant economic damage and the loss of structures with cultural and historical value. Currently, the response of masonry bridges under extreme loading is evaluated using simplified models due to the lack of efficient detailed models. However, these approaches do not allow for the complex 3D behaviour potentially leading to unrealistic and unsafe predictions. The main challenge of this project is the development of a more advanced strategy, based on a novel numerical description allowing for the 3D interaction between the different bridge components under extreme loading. More specifically, I will develop an efficient 3D finite element representation with macro-elements for the masonry parts of the bridge, an accurate description for the physical interface between masonry and backfill and an effective model calibration strategy utilising the results of non-destructive tests.

Keywords: natural risk assessment,structural failure,cultural heritage preservation,historical bridges,high,fidelity models,macro models,non linear analyses,seismic and flood risk assessment