Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Exploiting Superconvergence in Meshes for Optimal Representations of the Geometry with high Accuracy (ESMORGA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-12-01
End date: 2022-11-30
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: SIGNED

High-fidelity simulations using supercomputers play a key role in aerospace and automotive design for reducing the number of ground and in-flight tests. The mesh lies at the heart of the simulation: it reproduces the geometry using elements that, for engineering applications, are required to be curved (high-order). This project exploits geometric superconvergence: extra accuracy using lower order elements. The main goal is to transform observed geometric superconvergence into theory. The originality of this work is to derive the mathematics behind geometric superconvergence including theoretical limits and to develop a parallel code for High Performance Computing (HPC). The action features a two-way transfer of theoretical and practical knowledge between the fellow and the host institution in the topics of superconvergence, high-fidelity geometry simulations and HPC. The fellow will be integrated in the internationally recognized Geometry and Meshing for Simulation group at the Barcelona Supercomputing Center (BSC). This action is devised to have significant impact on the fellow’s career, becoming an expert in superconvergence both for numerical approximations and geometry within the unstructured high-order simulations community focused on aircraft design. The proposal has the potential to establish the fellow as core scientist in the emerging research area of superconvergence and high-fidelity flow simulations, allowing the candidate to start and lead a new research group. The work packages and methodology have been devised to reach the goals on high-fidelity geometry for simulation including parallel implementation for large data clustering. A risk assessment plan has been designed ensuring that at least suboptimal superconvergence theory can be derived. The BSC infrastructure will be essential for the implementation of this high-fidelity geometry tool; it houses MareNostrum4, one of the most powerful supercomputers in Europe.

Keywords: unstructured high order meshes,curved mesh generation,superconvergence
Decoding Hox specificity from mRNA processing networks (RNA-NetHOX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-01
End date: 2023-12-31
Duration (months): 24.0
Total project cost (EUR): 184707.84
EU funding (EUR): 116953.92
Participants: 1
Project status: SIGNED

Cell fate decisions is governed by the fine-tuned regulation of gene expression in all living organism. It is mostly realized by the cell-type specific assembly of regulatory networks consisting of Transcription Factors (TFs) and cofactors proteins. Thus, a multitude of combination between TF and cofactors will be set up to regulate the transcription in a precise spatiotemporal manner. The evolutionary conserved class of Hox TFs perfectly illustrates how a restricted number of TFs is able to promote diverse transcriptional programs. Hox proteins are involved in the specification of body forms and organs in animals. Despite this notorious architectural role, their operating mode remains controversial: they recognize similar DNA-binding sites in vitro, in sharp contrast with their specific functions in vivo. Thus, Hox proteins are likely acting with cofactors in vivo, and their identification was the core of my post-doctoral work. Notably, it revealed that mRNA-processing related proteins could constitute an important class of Hox cofactors. Thus, Hox specificity could also rely on mRNA-processing regulation, providing insightful molecular entry points to understand Hox function in development and disease. My research project aims at elucidating this novel facet of Hox activity. I propose two complementary aims developed in two model systems in order to decipher the molecular and functional impact of Hox-dependent mRNA processing regulation. I will decipher how interactions with splicing factors impact on the Hox functions in vivo in Drosophila embryos. Moreover, I will enlarge the cooperative role of HOX and splicing factors by performing large-scale interaction-screens of several human HOX and 2000 RNA-regulatory proteins in various normal and pathological cell contexts. Overall, my research program has the ambition to open novel perspectives on the role of TFs at the mRNA-regulatory level.

Keywords: protein protein interaction,splicing,system biology,drosophila,human cell line
Identifying the food cultures of ancient Europe: an interdisciplinary investigation of plant ingredients, culinary transformation and evolution through time (PLANTCULT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Austria,Germany,Switzerland,Greece
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-04-01
End date: 2022-03-31
Duration (months): 72.0
Total project cost (EUR): 1891875.0
EU funding (EUR): 1673675.0
Participants: 5
Project status: CLOSED

The project seeks to explore culinary practice among early farming European communities, from the Aegean to Central Europe, spanning the Neolithic through to the Iron Age (7th-1st millennia BC). The project seeks to identify the ‘food cultures’ of prehistoric Europe, and to reconstruct how cultivated and wild plant foods were transformed into dishes exploring their underlying cultural and environmental contexts and their evolution through time. The project will explore how culinary identities were shaped through the selection of plant foods both in terms of ingredients as well as processing and cooking practices. Thus not only species and meals but also the equipment involved in plant food preparation will be considered for the study area, linking the end product to the relevant technologies of transformation. Macroscopic and microscopic examination of the archaeological finds and experimental replication of various aspects of food preparation techniques informed by ethnographic investigations will form the main analytical tools. The interdisciplinary and contextual examination of the archaeological record will provide a fresh insight into prehistoric cuisine in Europe, the transformation of nature to culture through cooking. The project will revolutionise perceptions of prehistoric food preparation providing insights for the ‘longue durée’ of traditional plant foods constituting Europe’s intangible cultural heritage.

Keywords: archaeobotany,ancient food studies,starch analysis,phytolith analysis,ground stone tool technology,tool use wear analysis,cooking devices,prehistoric cuisine
Developing a Financial Econometrics Package for the Julia Programming Language (juliaeconometrics)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 187419.6
EU funding (EUR): 187419.6
Participants: 1
Project status: CLOSED

Julia is a new programming language started at MIT, with a strong focus on numerical computing. Its key advantage compared to languages like R and Python is that Julia is (just in time) compiled, rather than interpreted. As a consequence, Julia effectively combines the convenience of these high level languages with the speed of compiled low level languages such as C++ or Fortran. Speed of execution is critical in many applications, including but not limited to those involving big data. One critical aspect of any scientific programming language is its ecosystem, that is, the collection of libraries which implement common scientific functionality. In Julia, these take the form of packages. Packages are contributed by the user community and hosted in an online repository. They can be conveniently installed from within the language itself, similar to R and its CRAN network. Currently there are more than 1000 packages listed. The aim of the project proposed here is to build a Financial Econometrics package for Julia, as this functionality is presently absent. This package would become part of the official repository, and hopefully become the standard way of doing financial econometrics in Julia. Like Julia itself, the results of the project would be available under an open source license, an important aspect of open science. Open source software, via R and Python, has already made inroads into scientific computing, but financial econometrics is still a stronghold of commercial closed-source products like Matlab. This project will offer researchers in the field an alternative.

Keywords: garch,high frequency data,julia,matlab,python
Functional relevance of mitochondrial supercomplex assembly in myeloid cells (MY MITOCOMPLEX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-11-01
End date: 2024-01-16
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: SIGNED

The emerging field of immunometabolism has a strong potential to uncover novel targets for the manipulation of immune cell function. Myeloid cells are involved in innate and adaptive immunity and tolerance, therefore the identification of pathways that regulate their activity may have implications in many diseases. Research in the host laboratory has focused on how sensing of innate stimuli (infections and tissue damage) lead to mitochondrial adaptations in myeloid cells. These mitochondrial adaptations can influence the electron transport chain (ETC), resulting in differences in reactive oxygen species (ROS) production, ATP synthesis, redox balance and metabolites. The ETC consists of four respiratory complexes (CI-CIV), which can, excluding CII, form super complexes. The formation of these super complexes is regulated and this regulation has been shown to have biological relevance. However, whether mitochondrial SC organization couples to regulation of immune cell function and the molecular mechanisms involved is not known. Therefore, we propose to investigate how mitochondrial SC formation affects macrophage and dendritic cell function. Identification of the mechanisms connecting mitochondrial adaptations and myeloid cell function could potentially unveil therapeutic targets. Much immunometabolism studies could be improved by in vivo models, therefore we aim at studying the effects of SC formation regulation in vivo. We intend to use targeted and non-targeted approaches to address this question. A mouse model that exhibits a non-active SC assembly factor (SCAF1) will be a key tool to address this question in vivo. The non-independent approach includes state-of-the-art metabolomics and transcriptomics.

Keywords: dendritic cells,immunometabolism,mitochondria,supercomplex
Nanoscale Electrochemistry on Light Metallic Alloys (NELMA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2020-05-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

This proposal presents unique approaches for the characterization of light metal (magnesium as an exemplar throughout) alloy interfaces at the nanoscale in aqueous media, through the implementation of innovative, quantitative high-resolution scanning electrochemical probe microscopy techniques. The overarching goal is to introduce new methodology that will enable a comprehensive understanding of the influence of nanoscale inhomogeneities in the dissolution of light metal alloys. The scientific scope of this project involves: (i) determining the behaviour of different individual single entities (such as grains, grain boundaries, inclusions) on the heterogeneous surfaces of Mg-based alloys at the nanoscale, isolated from the rest of the surface (ii); progressing to the visualization of interacting surface sites and associated reactive fluxes during alloy dissolution; and (iii) nanostructuring at the nanoscale, as a new way for the rational study of surface treatments to improve alloy durability, which are of fundamental and technological (e.g. structural application bodies, bioimplants, batteries etc.) importance. The research proposal is highly interdisciplinary, and there is a natural synergistic fit between the Fellow’s profile and activities at the Host Warwick group. The project brings together the considerable expertise of the Fellowship applicant in light metal alloys and corrosion with that of the Host group in frontier correlative electrochemical microscopy to create new approaches that will greatly advance this important field. With considerable support and world-class expertise from the Host group and its collaborators, this project will provide the applicant, Dr. Viacheslav Shkirskiy, with an outstanding opportunity to develop personally and professionally, by pioneering a new area of research in a new geographic location.

Keywords: mg alloy,metal dissolution,localised galvanic corrosion,corrosion inhibitors,surface treatment,local electrochemical mapping,nanoscale
RESEARCH RIDE @CLIMATE WEEK (RESEARCH RIDE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Germany
Call: European Researchers' Night (H2020-MSCA-NIGHT-2018, 2018)
Start date: 2018-06-01
End date: 2020-01-31
Duration (months): 20.0
Total project cost (EUR): 290000.0
EU funding (EUR): 290000.0
Participants: 4
Project status: CLOSED

Hamburg has been the place of four successful European Researchers’ Nights from 2009 to 2012 with around 30.000 visitors and more than four million people reached by the awareness campaign each year. Learning from our past events, we want to broaden our reach with a unique and attractive concept, for 2018 and 2019. RESEARCH RIDE will combine science and fun to raise awareness to the impact of research in our FUTURE LIFE, to enhance researchers’ public recognition and to stimulate interest in research careers. RESEARCH RIDE is a special train, operating between Hamburg’s main stations on the Hamburg metropolitan network on Friday night between 5 p.m. and 11 p.m reaching 70,000 people. Inside the waggons different event-formats will be presented, such as presentations, insta-photo booth, exhibitions, elevator-pitches, speed dating with experts, TED talks etc. Direct interaction between the public and MSC researchers and project coordinators of many trendy and entertaining EU funded projects on the train, will be provided in an exciting atmosphere for young people between 14 and 25 years. Additionally, side-events taking place in seven metro stations on the line of the RESEARCH RIDE will be promoted directing the visitors to many research associated locations. With the help of the Young European Federalists of Hamburg, in order to create a better understanding of the EU and promote European networking, the EU waggon during the event will visualize the spirit and role of the EU in general with a particular focus on its predominant part in research. To maximize the outreach outcome of the European Researchers’ Night, essential pre-events will take place during the Hamburg Climate Week. A trendy cultural (i.e. open-air movie-screenings) and educational programme (workshops with school children inside the Climate Planet preparing material presented during the RESEARCH RIDE) will advertise the proposed RESEARCH RIDE. So let’s take a walk on the RESEARCH RIDE!

Keywords: hands on activities with researchers and scientists in trains of the metropolitan system of hamburg,key note future life,pre events during hamburg climate week
Secure Interoperable Full-Stack Internet of Things for Smart Home (SIFIS-HOME)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Germany,Italy,Italy,Italy,Finland,Finland,Sweden,Sweden,Finland,Sweden,Luxembourg
Call: Building blocks for resilience in evolving ICT systems (H2020-SU-ICT-2019, 2019)
Start date: 2020-10-01
End date: 2023-09-30
Duration (months): 36.0
Total project cost (EUR): 4754875.0
EU funding (EUR): 4754875.0
Participants: 14
Project status: SIGNED

SIFIS-Home aims at providing a secure-by-design and consistent software framework for improving resilience of Interconnected Smart Home Systems at all stack levels. To this end, the framework enables the development of security, privacy aware and accountable applications, algorithms and services, and makes it possible to detect and dynamically react to cyber-attacks and intrusion attempts or violation of user-defined policies, thus increasing control and trust of Smart Home end users. Smart Home is an emerging application paradigm which has been gaining increasing popularity. Most recently, the Internet of Things (IoT) has been fostering a vision of Smart Home systems, where users can install connectable (smart) devices and appliances that cooperate to automatically manage home services and functionalities. This emerging market is rapidly attracting software developers to produce novel applications and services, to provide additional Smart Home functionalities. However, noticeable barriers and concerns are still present, mainly related to cyber-security and safety within Smart Home systems, as well as to the privacy and integrity of produced and consumed data, most of which are personal and sensitive. Also, many Smart Home devices use custom and proprietary security solutions that do not account for interactions with other devices in the Smart Home system. Plus, developers have to develop applications adaptable to different systems and architectures, where security aspects are often neglected or poorly addressed. The consortium combines leading industry players in the IoT, telecommunication and cyber-security markets with research and academic institutions, also involved as key contributors to premier international standardisation bodies (e.g. IETF), and having leading roles in the SPARTA, CONCORDIA and CyberSec4Europe projects of the European Cyber Competence Network. SMEs active in the Smart Home and IoT markets and Open Source community complete the consortium.

Keywords: smart home,internet of things,cybersecurity audit,privacy audit,certification,standardisation,privacy friendly,secure software,secure hardware
Aurora Alliance - Research and Innovation for Societal Impact (AURORA RI)

Framework: Horizon 2020 — Science with and for Society
Action type: Coordination and support actions
Countries involved: Austria,Germany,Spain,Italy,Iceland,Czechia,Netherlands,Denmark,United Kingdom
Call: Support for the Research and Innovation Dimension of European Universities (Part II) (H2020-IBA-SwafS-Support-2-2020, 2020)
Start date: 2021-10-01
End date: 2024-09-30
Duration (months): 36.0
Total project cost (EUR): 2000021.25
EU funding (EUR): 2000021.25
Participants: 9
Project status: SIGNED

The Aurora RI project builds excellent research support structures to complement excellent research and innovation in the Aurora Alliance, a European University funded by the EC. It will further deepen and expand the cooperation among the universities and strengthen their identity as research-intensive universities dedicated to societal impact and engagement. The aim of Aurora RI is to develop a research and innovation support agenda framed by the SDGs and based on the four priority domains of the Alliance, i) Sustainability and Climate Change, ii) Digital Society and Global Citizenship, iii) Health and Wellbeing, and iv) Culture, Diversity. The focus of the project is to achieve an understanding of best practices and policies on sharing of research infrastructure and resources, cooperation on entrepreneurial activity, empowering human capital, mainstreaming open science and citizen engagement. Throughout the project we will analyse and map best practices already in place, learn from each other and define barriers to cooperation at national and international level and find ways to overcome these barriers. The findings will create the basis for our R&I support agenda and will be shared with the other European Universities and beyond. The actions implemented during the project period aim at creating a platform for cooperation that will sustain beyond the lifetime of the project and equip researchers and students at Aurora Universities with a broad toolkit to conduct excellent research and disruptive innovation.

Keywords: research and innovation support,open science,research infrastructures,citizen engagement,human resources,entrepreneurship