Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Renewables for clean energy buildings in a future power system (RES4BUILD)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Research and Innovation actions
Countries involved: Germany,Ireland,Germany,Sweden,Poland,Belgium,Greece,Belgium,Greece,Poland,Sweden,Netherlands,Netherlands,Netherlands,Denmark
Call: Renewable energy system integrated at the building scale (H2020-LC-SC3-2018-RES-TwoStages, 2018)
Start date: 2019-05-01
End date: 2023-04-30
Duration (months): 48.0
Total project cost (EUR): 4999702.5
EU funding (EUR): 4999702.5
Participants: 19
Project status: SIGNED

RES4BUILD will develop renewable-eneRRES4BUILD develops renewable energy-based solutions for decarbonising the energy used in buildings. The approach of the project is flexible, so that the solutions are applicable to a wide variety of buildings, new or renovated, tailored to their size, their type and the climatic zones of their location. In the heart of the solution lies an innovative multi-source heat pump with a cascading configuration, including a magnetocaloric (bottom cycle) and a vapour compression heat pump (top cycle). The heat pump will be combined with other technologies in tailored made solutions that suit the specific needs of each building. These technologies will be selected on a case by case basis from a mix of standard equipment available in the market and from innovative components that will be specifically explored within the project. The innovative technologies include innovative collectors that integrate in one panel photovoltaic cells and solar thermal energy collectors (PV/T) and borehole thermal energy storage (BTES). For all solutions, advanced modelling and control approaches will be developed and will be integrated in a Building Energy Management System, allowing the users to select their objectives and to optimise the use of the system accordingly, allowing the activation of demand response and the exploitation of the full value of smart appliances and smart charging of electric vehicles. The project adopts a co-development methodology, where the end-users and other relevant stakeholders are engaged in an interactive process, where a RES$BUILD system is designed for their buildings with their active participation. In parallel, a full life cycle assessment and life cycle costing analysis will be carried out, showing from an early stage the real impact of each proposed design. The diverse consortium and the dedicated exploitation tasks will connect the project with the market, paving the way for wide application of the developed solutions.

Keywords: integrated energy system,heat pump,magnetocaloric,pv thermal,stakeholders,building energy management system,advanced control,borehole thermal energy storage
Protecting weather-dependent industries from climate change: developing an affordable service for anticipating 100% of thunderstorms (STORM H-1)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-10-01
End date: 2022-09-30
Duration (months): 36.0
Total project cost (EUR): 2333250.0
EU funding (EUR): 1633275.0
Participants: 2
Project status: CLOSED

Thunderstorms are one of the hardest meteorological phenomena to accurately forecast, causing severe economic and security risk in weather-dependent industries (which represent around 70% of the economy). Across Europe, climate change has seen violent storm events rise by 350% in the past ten years, meaning that managing storm risk is a growing concern for protecting business activities, workers and the general public. SELERYS has developed a unique technology that can anticipate 100% of thunderstorms, 40-60 minutes in advance and with 100m accuracy. The solution is currently based on deploying our specialized radar via our own network (in France) and realtime storm risk alerts via our adapted interface. SELERYS has also developed an advanced prototype of “EVEARLYS”: a sensor capable of detecting convective activity in a developing storm cloud and therefore providing even more accurate predictions. EVEARLYS is the only industrial tool on the market providing laboratory quality storm detection, at accessible prices. Our technology has the potential to transform the management of storm risk across Europe and guarantee that no organization will ever again be “surprised” by a violent thunderstorm. The aim of the project is to deploy services based on our technology across Europe, and to reach clients in weather dependent industries (construction, heavy industry, water management…). This involves industrializing production of our EVEARLYS sensor (WP1) and developing it as a standalone solution for the creation of effective storm anticipation service (WP2). Pilot studies (WP3), the development of strategic partnerships (WP4) and market evangelisation (WP5) will prepare our solution for wide-scale deployment. Our aim is to rapidly impose SELERYS as a European market leader in the storm risk management field - benefiting European industry and the security of its population.

Keywords: meteorology,weather,climate change,security,radars,sensors
AN INNOVATIVE ANALYTICAL PLATFORM TO INVESTIGATE THE EFFECT AND TOXICITY OF MICRO AND NANO PLASTICS COMBINED WITH ENVIRONMENTAL CONTAMINANTS ON THE RISK OF ALLERGIC DISEASE IN PRECLINICAL AND CLINICAL (Imptox)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Understanding health, wellbeing and disease
Action type: Research and Innovation actions
Countries involved: Austria,Italy,Switzerland,Belgium,Belgium,Sweden,Belgium,Croatia,Serbia,France
Call: Micro- and nano-plastics in our environment: Understanding exposures and impacts on human health (H2020-SC1-2020-Single-Stage-RTD, 2020)
Start date: 2021-04-01
End date: 2025-03-31
Duration (months): 48.0
Total project cost (EUR): 6104823.75
EU funding (EUR): 6104823.25
Participants: 12
Project status: SIGNED

There is an urgent need to understand the risks on human health of micro- and nano-plastic particles (MNPs) that contaminate food and environment. We aim to create a cross-disciplinary platform to design suitable analytical approaches for determining the extent of the problem in the environment and to our health by evaluating the influence of ingested and inhaled exposure of MNPs contaminated with metals, allergens, pathogenic bacteria and toxins on allergic responses. Our strategy includes developing a novel combination of tools to identify, extract, characterize, and quantify MNPs from selected foods, environmental media, and tissues of exposed animals to assess MNP prevalence based on size, shape and type. We will produce and label MNPs for use in a variety of pre-clinical studies to investigate toxicity and responses to MNPs, contaminants and allergens. We plan to use novel stable isotope 13C labelling and detection to determine MNP fate and accumulation in the gastrointestinal and respiratory tracts and secondary organs after immediate and chronic exposure and the effect on allergic immune responses at the cellular and molecular levels. Additionally, we designed a clinical study to evaluate the influence of MNP exposure in humans. The outcome of this state-of-the-art project includes - novel tools for MNP detection - improved understanding of the effects of NMPs combined with critical contaminants in the air, water and food on human health and discovery of predictive biomarkers - increased awareness of disease risk in response to MNPs and contaminants - improved communication strategies between science and relevant stakeholders and contribution to blue growth and the health-relevant aims of the European Strategy for Plastics in a Circular Economy - policy-relevant scientific data in support of improved human health hazard and risk assessment and for response and mitigation policies at the national and EU level for policymakers. ImpTox is part of the European MNP cluster on human health.

Keywords: microplastics,absorption,contaminant,environment,diet,allergy,asthma,digestion,toxicity,pathogenic microorganisms,isotope ratio mass spectrometry
Meeting of Energy Professional Skills (MEnS)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Market uptake of energy innovation
Action type: Coordination and support actions
Countries involved: Germany,Spain,Ireland,Italy,Cyprus,North Macedonia,Belgium,Greece,Romania,United Kingdom,United Kingdom,Denmark
Call: Construction skills (H2020-EE-2014-3-MarketUptake, 2014)
Start date: 2015-03-01
End date: 2017-08-31
Duration (months): 30.0
Total project cost (EUR): 1478160.0
EU funding (EUR): 1478160.0
Participants: 13
Project status: CLOSED

MENS is a project conceived in order to provide an enhance the NZEB skills of building managers such as engineers and architect through a series of accredited training activities developed by 9 universities and 3 market players. MENS aims: - To increase the knowledre and skills of at least 1800 building managers (engineers, architects) in NZEB design and construction, out of which 50% would be women or unemployed. - To create and implement a new education and training program for such professionals in 10 countries, under the European Qualifications Framework provisions and based on desired and common learning outcomes of Level 7. - To create and implement an innovative, interdisciplinary education and training program with an integrated approach, focusing on real case studies - To accredit courses using the formal procedure in each country and assign ECTS credits. - To enhance and support the development of a professional network in Europe specifically focused on retrofitting of housing stocks towards NZEB. A connection with over 250,000 stakeholders and market players. - To provide working opportunities to unemployed professionals, by bringing them closer to possible employers and improving their qualifications, at a percentage of 30% of those attending. - To continue the education and training courses for at least 5 years after the end of the project based on concrete sustainability plans agreed by University partners. - To result in energy savings and/or increased use of renewables of at least 28,96 GWh/year. MENS is developed through 3 sets of training activities: national accreditation professional courses; e- learning and webinars: and case studies experiences around Europe and it involves involves major universities and stakeholders either directly or as Associated Partners engaged with LOS. MENS finally benefits from a strong media promotional activity through a wide network of local TVs and RTBF.

Keywords: training with accreditation for building managers,architects and engineers,nzeb,women in building environment,employability,educational integrated approach
ECaBox "Eyes in a Care Box": Regenerating human retina from resuscitated cadaveric eyes (ECaBox)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Spain,Israel,Italy,United Kingdom,Portugal
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2020)
Start date: 2021-09-01
End date: 2025-08-31
Duration (months): 48.0
Total project cost (EUR): 3552143.75
EU funding (EUR): 3552143.75
Participants: 7
Project status: SIGNED

In the last decade, basic and translational research dramatically expanded the development of new drug and regenerative therapies. Nevertheless, numerous potential therapies end up in the “valley of death” due to high attrition rates of preclinical development. More cost-effective preclinical research is needed to support radically new therapeutic interventions (e.g. regenerative medicine). Yet, preclinical research still lacks adequate models of human organs and even though human organoids approaches are a major step forward in mimicking physiological conditions, they fail to reflect the overall tissue physiology and complexity. To address this demand, we aim to develop a revolutionary platform, the ECaBox (Eyes in a Care Box) to resuscitate the human cadaveric eye while ensuring eye function and structure ex vivo for an unmatched time-period. This new technology will challenge current paradigms of testing the efficacy and safety of regenerative therapies ex vivo. We will therefore, explore the potential of this forefront technology by testing a regenerative therapy approach for retina degeneration. Currently, human eyes can be kept at 4ºC for 2 days before going massive and irreversible cell and tissue damage. Human dissected retinae from cadaveric eyes can be preserved for maximum 1 week and non-vascularised human eye organoids fail to recapitulate the vascular and tissue systems. Hence, ECaBox will be a disruptive technology with a tremendous impact allowing to: 1) resuscitate human eyes to test human eye therapies ex vivo, 2) bypass major ethical restrictions of human experimentation, 3) serve as a proof of concept to develop therapies also in other organs preserved ex vivo and 4) transform the existing organ transplantation field. This is a highly interdisciplinary project that integrates expertise in biology, biotechnology, modelling, engineering and physics.

Keywords: stem cell biology,electrophysiology,drug therapy,sr microscopy
ITEMB: Integrated Full Composite Main Landing Gear Bay Concept (ITEMB)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Italy,Italy
Call: Integrated main landing gear bay (H2020-CS2-CFP02-2015-01, 2015)
Start date: 2016-09-01
End date: 2018-08-31
Duration (months): 24.0
Total project cost (EUR): 802125.0
EU funding (EUR): 580237.5
Participants: 3
Project status: CLOSED

The standard solution of a landing gear integrated into the wings, that is widely used in the actual single aisle aircraft configuration, even if extensively safe in terms of structural load distribution, leads to many drawbacks both referred to the structural configuration and weight and also related to the structural integration of the different components during the aircraft final assembly and set-up. New solutions need to be supported by a big efforts in terms of design and materials optimization and manufacturing processes. The scope of ITEMB project is to set up an innovative Lower Center Fuselage (LCF) architecture compliant with Body Landing Gear scenario, including high loaded structure, highly integrated concept and industrial processes validation.

Keywords: landing gear bay,integrated main landing gear bay,composite,integrated composite landing gear bay
Mitochondrial methylation and its role in health and disease (MitoMethylome)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Sweden
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-04-01
End date: 2022-09-30
Duration (months): 66.0
Total project cost (EUR): 1499999.25
EU funding (EUR): 1499999.25
Participants: 1
Project status: CLOSED

Mitochondria and mitochondrial function have gained increased attention within a wide range of clinical and scientific specialities, but exactly how mitochondria impact the rest of the cell is less well understood. Not only are mitochondria implicated in a range of rare genetic disorders, but dysfunction of mitochondria or reduced bioenergetic capacity has been associated with common diseases including cancer, heart failure, neurodegeneration and diabetes mellitus, as well as natural ageing. It is becoming increasingly clear that mitochondrial dysfunction is not only a downstream event in these conditions, but plays an important role in disease progression and pathology. S-adenosylmethionine (SAM) is the dominant methyl group donor within our cells, required for a diverse set of post-translational modifications, nucleotide methylations or the synthesis of co-factors and metabolites. Mitochondria play an important part in SAM synthesis, and mitochondrial function has recently been shown to influence cellular methylation. Approximately 30% of the cellular SAM pool is located within mitochondria, advocating a central role for mitochondria in cellular methylation. The advancements in genome sequencing techniques, unprecedented depth of modern mass spectrometry analyses and our possibility to efficiently generate model systems, provides a rare opportunity to comprehensively study the role of both SAM and mitochondria in health and disease. This project plan describes the genetic, molecular, metabolic and proteomic analysis of fruit fly and mouse models with mitochondrial dysfunction and disrupted intra-mitochondrial SAM levels to identify the mitochondrial methylome, its relevance towards other cellular functions and its impact on the epigenetic control of gene regulation. My extensive research on mitochondrial function, as well as working as a physician with patients suffering from inborn errors of metabolism gives me a unique perspective in this project.

Keywords: inborn errors of metabolism,mitochondria,methylation,s adenosylmethionine,drosophila melanogaster,mouse,molecular biology,proteomics,mitochondrial disease,metabolism,bioenergetics
Mathematical aspects of three-dimensional water waves with vorticity (3DWATERWAVES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Sweden
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-03-01
End date: 2022-02-28
Duration (months): 72.0
Total project cost (EUR): 1203627.0
EU funding (EUR): 1203627.0
Participants: 1
Project status: CLOSED

The goal of this project is to develop a mathematical theory for steady three-dimensional water waves with vorticity. The mathematical model consists of the incompressible Euler equations with a free surface, and vorticity is important for modelling the interaction of surface waves with non-uniform currents. In the two-dimensional case, there has been a lot of progress on water waves with vorticity in the last decade. This progress has mainly been based on the stream function formulation, in which the problem is reformulated as a nonlinear elliptic free boundary problem. An analogue of this formulation is not available in three dimensions, and the theory has therefore so far been restricted to irrotational flow. In this project we seek to go beyond this restriction using two different approaches. In the first approach we will adapt methods which have been used to construct three-dimensional ideal flows with vorticity in domains with a fixed boundary to the free boundary context (for example Beltrami flows). In the second approach we will develop methods which are new even in the case of a fixed boundary, by performing a detailed study of the structure of the equations close to a given shear flow using ideas from infinite-dimensional bifurcation theory. This involves handling infinitely many resonances.

Keywords: water waves,free boundary problems,dispersion,three dimensional flows,travelling waves,vortex rings,bifurcation theory,variational methods,elliptic pdes,resonance,spatial dynamics
Heat Transport and its Effects on the Performance of Nanostructured, Photonic Materials (PhotoHeatEffect)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 175419.6
EU funding (EUR): 175419.6
Participants: 1
Project status: CLOSED

The PhotoHeatEffect project aims to create a breakthrough in our understanding and ability to control heat transport and exciton-phonon coupling in nanophotonic structures. Both phenomena generate detrimental effects like local heating and charge carrier escape in current generations of light emitters. Bridging phononics and photonics will reveal the physics behind such device limitations, hence allowing to develop countermeasures leading to better phononic and photonic designs. Tailoring the heat flow and the coupling between the phonon bath and excitons in nanophotonic structures has strong potential for numerous applications with a wide scope comprising life sciences, optogenetics, electronics, and data transmission. The project will not only boost the European competitiveness in the fields of thermal transport and phononics, both still dominated by US scientists, but even strives to pioneer a unique linkage to photonics. By employing nitride materials - a key research asset in the EU and at the host institute - it will be possible to encompass a wide range of emitters that already affect our everyday life (Nobel Prize in Physics 2014). Such polar nitrides are an ideal choice as they are relevant for classical (light-emitting diodes) and non-classical light sources (few-photon emitters, nano-, and polariton-lasers), which are both suffering from the phononic properties dictated by the material system. The project will resolve this relation by manipulating the phononic dispersion relation and the excitonic dipole moment independently by a phononic crystal comprising by design tunable electric fields. An analysis of these manipulations will be achieved by combining two-laser Raman thermometry and µ-photoluminescence spectroscopy. While the latter technique and an analysis of the exciton-phonon coupling match the expertise at hand, the progression towards thermometry and phononics will boost the applicant’s track record supported by a unique network of partners.

Keywords: thermometry,heat transport,exciton phonon coupling,thermal phononic,photonic,and phoxonic crystals,phononic bandgaps,nitrides,quantum dots and wells,raman and photoluminescence spectroscopy