Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
QCD challenges in precision physics at the LHC (QCDchallenge)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Italy,Switzerland
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-01
End date: 2026-09-30
Duration (months): 36.0
Total project cost (EUR): 320924.16
EU funding (EUR): 320924.16
Participants: 2
Project status: TERMINATED

In the next decade, the experiments at CERN's Large Hadron Collider (LHC) will provide us with measurements of astounding precision, by shrinking experimental uncertainties to the level of 1%. These will be crucial to probe the fundamental laws of Nature at high energies. Indeed, small deviations between measurements and predictions of the Standard Model would signal the presence of new physics. To exploit the potential of the LHC, it is imperative that theoretical predictions will match 1% accuracy. In this context, Quantum Chromodynamics (QCD) poses one of the major challanges. Due to the relatively large QCD coupling constant, perturbation theory must be pushed to the frontier of third-order corrections, or Next-to-Next-to-Next-to Leading Order (N3LO). In addition, due to the multi-scale nature of QCD processes, perturbative corrections are enhanced by large logarithms of the scale ratios, which require to resum the perturbative series. This project will provide new methodologies for QCD calculations at high precision and state-of-the-art results for two complementary classes of enhanced contributions. One are the collinear logarithms, which govern the scale dependence of the parton distribution functions (PDFs). Building upon a breakthrough discovery that I achieved in multiloop renormalisation, I will compute the N3LO evolution of the PDFs, which addresses one of the largest sources of theoretical uncertainties at the LHC and enables QCD phenomenology to reach 1% accuracy. Another class of enhancements, known as high-energy logarithms, arises when the centre-of-mass energy of the collision is much larger than the momentum transfer scale. I will tackle the factorisation of the Next-to-Next-to-Leading Logarithms (NNLLs) in multi-leg amplitudes, building on recent progress in the calculation of multi-leg amplitudes and on a new approach that I developed to disentangle the building blocks of high-energy factorisation.

Keywords: quantum chromodynamics,precision calculations,scattering amplitudes,splitting functions
John Hume and the Creation of the European Dimension in Ireland (JHCEDI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-05-02
End date: 2026-05-01
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

John Hume and the Creation of the European Dimension in Ireland will investigate how John Hume helped to create the conditions for a diverse constituency in Northern Ireland to reimagine its political and cultural identity in Europe. The kernel of JHCEDI is a research question that has not been adequately addressed in the literature on Hume, or on Ireland in Europe: How did Hume’s reconceptualisation of Ireland in Europe facilitate the peace process in Northern Ireland? This project could hardly be more timely: a thorough public awareness of the history of Northern Ireland in Europe through the lens of its key political actor, Hume, over the past half-century could provide a vital contribution to public discourse and attitudes towards the future. Today three pillars of considerable geopolitical significance – the threat to the Good Friday Agreement, the disruptions of Brexit, and the ongoing controversies that surround the Northern Ireland Protocol – give urgency to JHCEDI. No work yet exists that fully transcends the paradigms in which Hume has been framed by situating Hume’s project in the paradigm of nation formation in a European tradition as well as in ethnic studies. This is the gap in the literature that JHCEDI will address. The vision he shared with t of a Europe of regions and of shared sovereignty was at once a transnational priority for Hume and a strategy to resolve Ireland’s internal dilemmas. The objective of JHCEDI is to investigate how Hume helped to create the conditions for a diverse constituency in Northern Ireland to reimagine their political inheritance. The outputs of JHCEDI will be the articles and the public dissemination of my findings, being essential actions to lay the groundwork for my monograph in this subject.

Keywords: democracy,human rights,transnational history,international history,european construction,brexit,ireland,peace process,pluralism,diversity,shared future
Integrated, domain-specific test automation solution for Air Traffic Management systems (ApprovAir)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Hungary
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2100000.0
EU funding (EUR): 2100000.0
Participants: 1
Project status: SIGNED

ApprovAir is the first vendor-independent test automation platform or domain specific testware developed specifically for highly specialized and safety-critical Air Traffic Management (ATM) systems. As a standards-based low-code/no-code solution, ApprovAir offers a unique combination of flexibility and specialization, featuring industry-specific drivers and extensions and a portable industry wide test suites. Thanks to our novel approach, at product level ApprovAir will be an ease-of-use, relatively quick-to-install, but easy-to-customize and extend tool that is quite unique in the ATM-related software segment. Our company has dedicated the last 5 years to R&D in this domain aiming to position ProofIT not just as a European market leader but as a global pioneer in the completely new ATM test automation market created by ApprovAir. As a result, our beta prototype is currently the only tool for automated regression testing of integrated air traffic control and management systems worldwide. In terms of TRL ApprovAir is on level 6. We have successfully demonstrated the beta system in relevant environments, showcasing its capabilities through direct POC demonstrations, as well as at key industry expos and conferences, resulting in a significant market interest underlined several Letters of Intent. Our key partnerships have been instrumental to our progress, including collaborations with HungaroControl and EuroControl, providing access to real-world environments and highly specialized knowledge. Furthermore, we have also established very valuable relationships with prominent ANSPs, ATM vendors, ATM integrators, and international regulatory and interest representation bodies. Looking ahead, our primary objective is to finalise ApprovAir product development and successfully enter the targeted market. As the main result of the proposed project, ApprovAir will become a new and very valuable component of the global ATM value chain.

Keywords: air traffic management,test automation,test efficiency,aviation safety,atm,atc,atfm,atco
A Limb-bud Integrated Microphysiological system to model the effect of Biophysical stimuli in musculoskeletal systems' Organogenesis (LIMBO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-12-01
End date: 2027-11-30
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

LIMBO aims to introduce a new class of microphysiological systems (MPSs) that replicate the mechanical microenvironment of the developing limb bud and integrate on-line volumetric spectroscopic analyses. This will provide new insights into biophysical factors in musculoskeletal tissue organogenesis, previously unknown due to technological limitations, and guide regenerative medicine approaches for age-related pathologies. Since Alan Turing's theorization in 1952, developmental biology has relied on the idea that morphogenesis stems from chemical patterns forming from initially uniform substances. Yet, advances in single-cell transcriptomics and lineage tracing have shown that biochemical and genetic instructions alone do not fully explain the self-organizing behavior of developing tissues. A new perspective suggests that mechanical forces are as crucial as gene expression and chemical diffusion, particularly for musculoskeletal tissues development; proper joint formation depends on muscle contractions and foetal movements. A major obstacle to understanding the "sculpting forces" driving tissue growth, shape, and differentiation patterns is the lack of technologies to measure the biophysical parameters of developing tissues, replicate the cell scale mechanical milieu, and monitor its temporospatial evolution. MPSs are gaining traction as tools to dissect developmental processes and observe molecular-scale dynamics. However, replicating the mechanics of developing musculoskeletal tissues - affected by cyclical strains, growth-generated internal stresses, and topography/localized curvature induced cues - presents peculiar engineering challenges. I propose a multidisciplinary approach that combines mouse embryonal limb bud cells with an MPS technology for cyclical mechanical stimulation, micro fibrous scaffolds, and acoustic cell patterning to replicate different mechanical cues, and with confocal Raman Spectroscopy Imaging to assess tissues biomolecular time evolution.

Keywords: organ on chip,microfabrication,mechanics,limb bud,confocal raman spectroscopy imaging
Minimally invasive and closed-loop ultrasound neuromodulation and recording for the treatment of focal epilepsy (URENIMOD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1499575.0
EU funding (EUR): 1499575.0
Participants: 1
Project status: SIGNED

Epilepsy is a common and debilitating chronic neurological disorder. Furthermore, a large fraction of patients suffers from refractory (drug-resistant) epilepsy. Responsive electrostimulation is a state-of-the-art treatment for refractory epilepsy but is invasive and not cell-type selective. As a result, the surgery is susceptible to complications, e.g., haemorrhage and infection, and overstimulation due to false-positive epilepsy detection can cause brain region overactivity and even induce seizures. In contrast, ultrasound neuromodulation (UNMOD) is a recent, non-invasive and cell-type selective technique, that promises to pave the way for truly inhibitory protocols. The goal of this project is to design and optimize a first-of-its-kind minimally invasive closed-loop UNMOD treatment for refractory epilepsy. Acousto-electric heterodyning will be used to realize remote non-invasive hippocampal neurorecording. Subsequently, a controller will detect seizures and will trigger neuromodulatory insonication with a miniaturized subcutaneously implanted phased array. Moreover, an alternative non-invasive and closed-loop technology will be designed, for testing and patient selection before implantation. The main hurdle towards the realization of this disruptive treatment is our limited understanding of the underlying mechanisms of UNMOD and acoustic neurorecording. I intend to close this knowledge gap by developing an experimentally validated, comprehensive and morphologically-realistic computational framework of the ultrasound-sensitive hippocampal formation. Subsequently, this model will be used to optimize the insonication and recording protocols and to design the transducer and electrode arrays. This project concentrates on focal epilepsy, but the envisioned minimally- to non-invasive, cell-type specific, closed-loop technology with millimeter resolution, has the potential to revolutionize also the treatment of other brain and peripheral nerve disorders.

Keywords: ultrasound neuromodulation,acousto electrophysiological neuroimaging,closed loop brain stimulation,deep reinforcement learning,epilepsy,computational modeling
Spectral Diversity within Ryugu (SDR)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-06-01
End date: 2026-09-30
Duration (months): 40.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

To understand the history of the chondritic asteroid Ryugu and whether it had a role in delivering volatiles and organic material to early Earth, SDR will constrain the mineral and geochemical variability of sediment samples from Ryugu on a grain and sub-grain scale. Because Ryugu is a rubble-pile asteroid made of re-accreted pieces of the parent body/bodies, near-surface sediment collected by the Hayabusa2 mission represents many depths within the interior of the parent. However, current analyses of collected reflectance spectra are done at the bulk sample scale which can average over interesting features to determine the major components. As individual grains are prepared to be sent out for proposed science, each grain is being documented from multiple viewing angles using the MicrOmega hyperspectral imager (0.99-3.65 micrometers) developed at IAS. This has created an enormous, rich dataset of ~20 hyperspectral images for each of 350 grains analyzed so far, and this dataset will continue to grow over the coming months. By conducting novel statistical analyses of this dataset of >7000 high-resolution image cubes (22 micrometers/pixel), I will identify co-occurring mineral phases, minor phases, and variation in organic phases that have implications for the aqueous alteration conditions within Ryugu and its parent body. Statistical analyses will include: principal component analysis, k-means clustering, distinctiveness measures, pixel-to-pixel correlation, edge detection, and network centrality. My experience publishing on statistical analyses of existing, noisy datasets has prepared me to extract meaningful information from this large, complicated dataset. This work will culminate in an updated model of formation and alteration on Ryugu’s parent body which relies on the types and position of minerals to infer alteration gradients and constrain the nature, number, and temperature of aqueous alteration events.

Keywords: asteroid,spectroscopy,alteration history
Chemistry informed machine learning in emulsion polymerization processes and products (CINEMA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,Belgium,Germany,France,United Kingdom,Netherlands
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 2062771.2
EU funding (EUR): 2062771.2
Participants: 10
Project status: SIGNED

Machine learning (ML) systems continue to revolutionize many aspects of daily life, but despite their immense potential have yet to impact significantly in polymer science. One major issue that is hindering the more widespread use of machine learning in polymer science, and many other physical sciences, lies in the challenges in amassing sufficient data to efficiently train machine learning models. This in itself is not necessarily a problem, and is an issue frequently encountered in the machine learning field, but can only be resolved by a thorough understanding of the science behind the problem of interest. CINEMA aims to providing a training platform that will allow the next generation of polymer scientists to take polymer science into the 21st century through incorporating the fundamental knowledge gained over many years of research into the training of machine learning systems. Such a knowledge-driven machine learning approach puts the scientific issues of CINEMA at the forefront of the use of machine learning in fundamental scientific problems, and also provides the perfect training platform for the next generation of scientists, for whom the use of AI will be an invaluable tool.
Living with Drought: Human -Environment Relationships in Drying European Landscapes (DROUGHT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Studies of Cultures and Arts
Panel description: Social anthropology, studies of cultur es, stud ies of arts
Countries involved: Norway
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-08-01
End date: 2030-07-31
Duration (months): 60.0
Total project cost (EUR): 1683750.0
EU funding (EUR): 1683750.0
Participants: 1
Project status: SUSPENDED

Recent multi-year droughts have led to severe and unequally distributed socio-environmental disruptions across Europe, the Earth’s fastest warming continent. Much more than short-term ‘crisis-events’ droughts pose long-term, multi-faceted cultural, political, and conceptual challenges to society that remain poorly understood. Adopting a comparative, multi-sited anthropological approach, this project will generate needed insights into how people—farmers, conservationists, politicians, foresters, scientists—and local communities learn to live with drought in human-dominated landscapes in Spain, Germany, and Norway. Combining state-of-the-art theoretical approaches from such varied disciplines as anthropology, geosciences, and the environmental humanities, DROUGHT seeks to meet three specific objectives: 1) to produce a novel integrative cultural theory of drought as an inherently relational and situated socio-cultural and geophysical process that unfolds in and through human-dominated landscapes; 2) to complete the first historically informed, in-depth ethnography of living with drought in Europe; and 3) to experiment with collaborative, sensory and more-than-human research methods as a way to explore the affective, experiential, and material manifestations of drought. Fulfilling these objectives will enable DROUGHT to achieve its overarching aim: to generate an empirically-driven, theoretically ambitious field of scholarship—anthropogenic drought studies—that will advance knowledge of droughts in the social and cultural fields while adding needed empirical depth and nuance to emerging science-centred discourses on droughts in the Anthropocene. The knowledge produced will help transform academic, public, and political understanding of, and debates over, what constitutes droughts, why they matter, and how we should respond to them.

Keywords: environmental anthropology environmental humanities multispecies studies more than human approaches perception of the environment socio cultural environmental change cultural landscapes anthropocene qualitative methods ethnography situated knowledge sensory methods
Towards faster super-resolution DNA optical mapping using plasmon-enhanced fluorescence (Plas_OpMap)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-07-01
End date: 2025-06-30
Duration (months): 24.0
Total project cost (EUR): 188548.0
EU funding (EUR): 188548.0
Participants: 1
Project status: CLOSED

Human microbiome science is advancing, showing promise of having important impacts on human health with new insights into disease etiology and general human biology. Accordingly, DNA sequencing platforms have been developed rapidly, expanding the scope in microbiome research. Among others, optical mapping technique, capable of imaging single DNA molecules provides access to genetic information on single molecules up to ~1 Mbp in length. It uses fluorescence imaging of linearly stretched DNA molecules labelled at specific sites to probe information patterns along the molecules. The precision of the method is further improved by resolving single molecules below the diffraction limit through super-resolution imaging. However, requirement of large photon budget slows down the speed of imaging, as long acquisitions are required to build up sufficient photons for precise localization. This affects the throughput of DNA optical mapping which involves imaging large areas, thereby limiting its capabilities in providing real-time information of the microbiome on daily basis. Enhancing the emission rates from single molecules can overcome this limitation to permit faster image acquisition. Here we propose to use plasmon-enhanced fluorescence by employing substrate made out of wet-chemically synthesized gold nanotriangles for optical mapping of human gut microbiome. Plasmonic nanostructures can confine incident electromagnetic field into small area near their surface leading to strong light absorption and higher emission rates from fluorophores in their vicinity. The use of wet-chemical plasmonic substrate exhibiting strong plasmon resonance can significantly increase the number of photons released from the labelled DNA, allowing faster image acquisition. With the improved speed, the time required for optical mapping analysis can be significantly shortened, enabling longitudinal metagenomic analysis with practical implications for quicker diagnosis and personalized health care.

Keywords: dna optical mapping,plasmon enhanced fluorescence,metagenomics,super resolution microscopy,gold nanoparticles