Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Machine Learning of Speech Recognition Models for Controller Assistance (MALORCA)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Germany,Austria,Germany,Switzerland,Czechia
Call: Data Science in ATM (H2020-SESAR-2015-1, 2015)
Start date: 2016-04-01
End date: 2018-03-31
Duration (months): 24.0
Total project cost (EUR): 805587.5
EU funding (EUR): 538103.75
Participants: 5
Project status: CLOSED

One of the main causes hampering the introduction of higher levels of automation in the Air Traffic Management (ATM) world is the intensive use of spoken language as the natural way of communication. Data link will be another media of communication with its known advantages compared to voice communication but for the future it is still assumed that data link communication will increase but never fully replace voice communication. Particularly for the time being controllers and pilots exchange information by spoken language, whereas automated systems understand the situation based only on sensor information. This difference in the end creates misunderstandings between operators and systems which lead to failures and further on to a lack of acceptance for automation. One promising solution is the introduction of automatic speech recognition as an integral part of automation. Recently, the venture capital funded project AcListant® has achieved command error rates below 2% based on Assistant Based Speech Recognition (ABSR), developed by Saarland University (USAAR) and DLR. ABSR combines speech recognition with an assistant system, which generates context information to reduce the search space of the speech recognizer. One main issue to transfer ABSR from the laboratory to the ops-rooms is its costs of deployment. Each ABSR model must manual adapted to the local environment due to e.g. different accents and deviations from standard phraseology. This project proposes a general, cheap and effective solution to automate this re-learning, adaptation and customisation process to new environments, taking advantage of the large amount of speech data available in the ATM world. Machine learning algorithms using these data sources will automatically adapt the ABSR models to the respective environment.

Keywords: assistant based speech recognition,automatic speech recognition,supervised and unsupervised learning,cost reduction
Design and photo-optimization of Photosensitizer for Human Health and Food security applications or “how light can save lives” (POLYTHEA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Joint Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Ireland,Switzerland,Poland,Greece,France,Netherlands,Portugal
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-01-01
End date: 2022-06-30
Duration (months): 54.0
Total project cost (EUR): 2548256.76
EU funding (EUR): 2548256.76
Participants: 7
Project status: CLOSED

The development of active compounds that can efficiently fight microbial infections and cancer are of utmost importance for food security and human health, two main challenges for Europe. Tetrapyrrolic photosensitizers (PS) are good candidates to meet these expectations. These photo-excitable molecules induce cell death via the formation of oxygen reactive species (ROS) and present very low toxicity in the absence of light. They are already used in photodynamic therapy (PDT) for cancer or skin disease treatments or in photo-antimicrobial chemo-therapy (PACT). Unfortunately, the research and training are still largely fragmented in this field in Europe. Some scientific barriers have to be overcome to increase their efficacy, e.g. improvement of the excitation pathways, ROS production, specific cell targeting, Gram (-) bactericidal effect and prevention and/or eradication of biofilms. That is why the EJD Polythea project aims developing an integrated and multidisciplinary approach of PDT through the implementation of 10 PhD research projects. The Polythea consortium proposes to develop (i) new tetrapyrrolic PS for various types of PDT including anti-cancer, anti-bacterial, anti-inflammatory and immune-activating application, improving their photophysical and biological properties; and (ii) innovative bio-inspired drug carriers or supports. In parallel, a joint doctorate structure gathering 5 countries will be created and a multidisciplinary and inter-sectorial training programme will be implemented through network events and secondments to non-academic partners. It will provide a common background on PDT to the ESRs and make them more valuable employees, effective at problem solving. Practical applications should come out of this project such as first aid bandages, new skin/anti-tumour treatments, self-sterilizing surfaces for food industry or prosthetic devices.

Keywords: photosensitizer design,drug carrier,formulations,anti cancer,anti arthrisis,food security,antimicrobial resistance,linear and non linear optical properties
Dual capillary waveguide endoscope (DARWIN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-01-01
End date: 2019-12-31
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 2
Project status: CLOSED

Photoacoustic imaging, an emerging multi-wave imaging modality that couples light excitation to acoustic detection via the photoacoustic effect (sound generation via light absorption), relies on detecting ultrasound waves that are very weakly scattered in biological tissue. It provides acoustic-resolution images of optical absorption non-invasively at large depth (up to several cm). However, ultrasound attenuation increases with frequency, limiting the depth-to-resolution ratio to about 100. An alternative to overcome the dispersion of light in tissue due to scattering is using thin, micron-sized diameter optical fibers to both deliver and collect light from the sample. A novel idea and preliminary proof-of-concept experiment has just been demonstrated by Prof. Bossy’s team where a dual waveguide allows also to remotely detect high frequency ultrasound with the same device as that used for guiding light. This device can act both as a multi-mode optical waveguide for the illumination and fluorescence collection using the outer cladding, and as a waveguide to guide the ultrasound out of the tissue using the core, avoiding the absorption by the tissue and increasing the penetration depth. The overall objective of DARWIN is to study and develop a new type of dual-modality endoscope for optical-resolution photoacoustic and fluorescence microscopy based on a capillary waveguide. To do so, a high speed phase modulator will measure the transmission matrix and calibrate the endoscope providing a way to display any optical patterns at the distal tip. The fellow will explore different configurations where a thin hydrophone, based on a single mode fiber or a needle, is inserted inside the core improving the acoustic signal detection. Furthermore, bending compensation will be investigated. DARWIN will result in a prototype thin endoscope for dual microscopy imaging, an important tool for in-vivo experiments, such as the neuron imaging.

Keywords: capillary waveguide,photoacoustics,wavefront shaping,multimode fiber,endoscopy
Polynuclear Gold Cluster Catalysis (PGOLDCAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-03-01
End date: 2019-02-28
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Gold catalysis has become an extremely attractive research field these last decades as it has been considered one of the most effective methodologies for constructing carbon-carbon or carbon-heteroatom bonds. However, the development of enantioselective catalysis mediated by gold is relatively slow, mainly due to (i) the preferred linear two-coordinated mode of AuI complexes in the activation of alkynes, thus making the π-activation substrates distant from the chiral site, and (ii) the lack of mechanism data for enantioselective gold(I)-catalyzed transformations. In this project, PGOLDCAT, we will focus on the synthesis of novel gold clusters, and silver analogues, for the catalytic activation of small molecules. The project includes the study of their catalytic performance in standard reactions and mechanism investigations by comparing the catalytic performance of gold clusters and silver analogues, together with kinetic studies and intermediates optimization by theoretical calculation. Finally, PGOLDCAT will study the application of these new architectures on developing a general asymmetric synthesis of 1,4-enynes. Overall, this research project will expand enantioselective AuI catalysis, giving insights into the gold-catalyzed mechanisms, and applying these catalysts to organic synthetic methodologies. The fellowship will also allow the experienced researcher to increase her network of contacts and follow a personalized career development plan to advance in her path towards an independent academic position.

Keywords: gold,catalysis,polynuclear clusters,enantioselective synthesis
Novel cooling system for the cryogen-free, continuous, and fully-automatic generation of very low temperatures near absolute zero. (CADR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-07-01
End date: 2019-11-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Low temperatures close to absolute zero (0 degrees Kelvin) are required for materials science, detectors for the aerospace and military sector, quantum computing, and quantum electronics. These temperatures are commonly achieved by using cryogenic liquefied gases (cryogens), such as liquid helium (He). However, there are a numbers of problems related to the use of these cryogens which include the oligopoly of He-3, high costs of cooling machines (€ 300-600k), and safety problems. To solve these pains, kiutra has developed a cryogen-free, continuous, and fully automatic refrigeration system based on a cryogenic magnetic cooling process known as Continuous Adiabatic Demagnetization Refrigeration (CADR). CADR uses widely available and low-price cooling media, saving € 20-40k/year in comparison with typical refrigeration systems that use He-3. Moreover, the system has a complete modular and customizable design, as it can be extended with multiple units according to the cooling requirements. It also offers a wide and stable temperature range while being easy to operate and hazard-free, thanks to the elimination of cryogens. kiutra, founded in 2018 in Germany, builds easy-access turn-key refrigeration solutions. Their cooling devices combine magnetic refrigeration and closed-cycle pre-cooling to provide cryogenic temperatures without cryogens. kiutra is currently funded by “EXIST Transfer of Research”, and has raised almost € 2M to date. The proposed work in Phase 1 of the SME instrument fits into their overall plan to reach market by contributing to the financial resources needed to further improve and test CADR system, and ensure market uptake.

Keywords: cryogens,cooling system,quantum technology,quantum computing,quantum communication
Attosecond plasmon imaging with electrons (ATTOPIE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 185857.2
EU funding (EUR): 185857.2
Participants: 1
Project status: CLOSED

This project „Attosecond plasmon imaging with electrons“ (ATTOPIE) aims at the experimental realization of the long-desired attosecond photoemission electron microcope (PEEM) to record plasmonic near-fields with nanometer spatial resolution directly on the field level. In this microscope, the attosecond temporal resolution of laser physics is combined with the nanometer spatial resolution of electron microscopy. An infrared pump pulse triggers ultrafast electron dynamics on the surface of a sample. With a certain time delay, an attosecond ultraviolet pulse probes these dynamics by emitting photoelectrons from the sample. These electrons are directly accelerated in the plasmonic near-field, imprinting the field’s local strength into the kinetic energy of the electron. The emission site and the kinetic energy of each electron is recorded in a photoemission electron microscope with few ten nanometer resolution. From the locally recorded kinetic energy spectra of the electrons for a series of pump-probe delays, the complete dynamics of plasmonic near-fields can be reconstructed on the field level. The realization of such an attosecond PEEM becomes possible by employing a state-of-the-art optical parametric chirped pulse amplification laser system with a repetition rate of 200 kHz to generate high harmonics and consequently attosecond pulses. With the increased repetition rate compared to conventional amplifier systems by a factor of 100, the measurement time is significantly reduced, rendering the experimental realization possible. This fundamental research on the described imaging technique with direct access to the propagation and interaction of localized fields on nanometer length- and femtosecond timescales will open up a multitude of research approaches to understand, e.g., nanometric energy transport for improved photovoltaics or petahertz information processing in future optical transistors.

Keywords: attosecond physics,photoemission electron microscopy
Mobile dual arm robotic workers with embedded cognition for hybrid and dynamically reconfigurable manufacturing systems (THOMAS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Technologies for Factories of the Future
Action type: Innovation actions
Countries involved: Germany,Spain,Spain,Spain,Germany,Greece,France,Luxembourg
Call: Machinery and robot systems in dynamic shop floor environments using novel embedded cognitive functions (H2020-FOF-2016, 2016)
Start date: 2016-10-01
End date: 2021-03-31
Duration (months): 54.0
Total project cost (EUR): 5624225.0
EU funding (EUR): 4510700.0
Participants: 8
Project status: CLOSED

The productivity of the serial production model is compromised by the need to perform changes in the production equipment that cannot support multiple operations in dynamic environments. Low cost labour is no longer an option for EU manufacturers due to the fast rise of wages and the increasing costs of energy and logistics. Manual tasks cannot be fully automated with a good ratio of cost vs robustness using standard robots due to: high product variability, dedicated process equipment and high cost of maintenance by expert users. The answer to this challenge lays in the creation of production concepts that base their operation on the autonomy and collaboration between production resources. The vision of THOMAS is: “to create a dynamically reconfigurable shopfloor utilizing autonomous, mobile dual arm robots that are able to perceive their environment and through reasoning, cooperate with each other and with other production resources including human operators”. The objective of THOMAS are to: - Enable mobility on products and resources. Introducing mobile robots able to navigate in the shopfloor and utilize dexterous tooling to perform multiple operations. - Enabling perception of the task and the environment using a) the individual resource’s and b) collaborative perception by combining sensors of multiple resources - Dynamic balancing of workload. Allowing the resources to communicate over a common network and automatically adjust their behaviour by sharing or reallocating tasks dynamically. - Fast programming and automatic execution of new tasks by a) automatically generating the robot program for new products and b) applying skills over the perceived environment to determine required adaptations - Safe human robot collaboration, eliminating physical barriers, by introducing cognitive abilities that allow the detection of humans and their intentions THOMAS will demonstrate and validate its developments in the automotive and the aeronautics industrial sectors.

Keywords: mobile robots,dual arm robots,robot skills,navigation,service oriented architecture,robotic 3d perception,human robot interaction,safety,dynamic workload balancing,simplified programming
Developing next-generation tools for mitochondrial dissection with cell-specific resolution. (MitoTAGs)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-01
End date: 2017-04-30
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Mitochondria generate most of the energy cells require to function. Deficits in the mitochondrial energy-generating machinery affect 1:5,000 children and cause progressive, debilitating, and usually fatal pathologies collectively known as primary mitochondrial disease. To date, there is no cure for mitochondrial disease and existing treatments are highly ineffective and mostly palliative. High-energy-requiring cells, such as neurons, are especially affected in mitochondrial disease. However, not all neuronal populations are equally affected. Furthermore, the molecular determinants of neuronal vulnerability to mitochondrial disease have not been adequately elucidated, representing a challenge for the development of efficient treatments for these pathologies. To improve on current knowledge on mitochondrial disease and to provide better therapeutic targets, this proposal focuses on developing ground-breaking molecular biology tools that will allow the identification and dissection of the molecular determinants of neuronal vulnerability in mitochondrial disease with unprecedented definition. I will develop novel techniques to isolate the mitochondrial translatome by using ribosomal tagging, as well as to assess intact mitochondrial function, with cell-type specificity. These novel approaches will have a high impact in mitochondrial disease research, with the overall aim of identifying novel therapeutic targets that will lead to effective treatments for mitochondrial disease. Furthermore, the high applicability of the tools generated will allow significant breakthroughs in the research of other pathologies with mitochondrial affectation such as diabetes or neurodegenerative processes.

Keywords: neuron,mitochondria,adeno associated viral vectors,mitochondria ribosome tagging,mitochondria tagging,loxp system
innovaTive disbOnd aRrest features for loNg thermoplAstic welDed jOints (TORNADO)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Greece,France,Netherlands
Call: Innovative disbond arrest features for long thermoplastic welded joints (H2020-CS2-CFP11-2020-01, 2020)
Start date: 2021-01-01
End date: 2023-06-30
Duration (months): 30.0
Total project cost (EUR): 864125.0
EU funding (EUR): 663012.5
Participants: 3
Project status: SIGNED

The aerospace industry currently has a need for lightweight, complex composite structures to make their way into operational use. Changes in the regulatory landscape and demands for reduced emissions, coupled with the need to optimize Revenue Passenger Kilometers (RPK), have driven research efforts into cleaner, lighter, and more efficient aircraft designs. A key approach to reducing emissions is minimizing weight: by reducing weight, fuel usage drops, leading to a reduction in overall emissions. This requires that traditional materials such as steel, aluminum, and even titanium be replaced with lighter, high-performance materials. High Performance Thermoplastics (HPTP) are an excellent solution to the issues of recyclability, light weight, high performance, and repairability. HPTP composites offer compelling advantages over metal components: improved working life, lower weight, reduced fuel consumption, and longer service intervals. The Large Passenger Aircraft (LPA) Platform 2–Multifunctional Fuselage Demonstrator (MFFD) will employ new combinations of airframe structures, cabin/cargo, and system elements using advanced materials, notably HPTP composites. The MFFD is focused on achieving significant cost and weight reductions, coupled with high production rates. The use of thermoplastic welding can lead to significant benefits, but in order to obtain certification under EASA and CS 23 rules, disbond arrest features must be integrated into the structure. The TORNADO project will develop a novel technology, Inductive Low-Shear Friction Stir Riveting, as well several other fallback alternatives, in order to provide a high-performance solution for disbond arrest in the MFFD.

Keywords: thermoplastic welding disbond induction rivets