Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Pan-European Access for man. SME on tech. services for clean production through a Network of premier KET Technology Centres with one stop shop access incl. EEN and discourse with policy makers on RIS3 (KET4CleanProduction)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Ireland,Austria,Germany,Germany,Spain,Germany,Bulgaria,Slovakia,Finland,Greece,Croatia,Hungary,Slovenia,Sweden,Sweden,Belgium,Latvia,France,Denmark,United Kingdom,Portugal
Call: Technology services to accelerate the uptake of advanced manufacturing technologies for clean production by manufacturing SMEs (H2020-INNOSUP-03-07-08-2017, 2017)
Start date: 2018-01-01
End date: 2021-09-30
Duration (months): 45.0
Total project cost (EUR): 4898510.0
EU funding (EUR): 4898510.0
Participants: 22
Project status: CLOSED

A multi-KET (key enabling technologies) approach is most beneficiary for SME in regard to increase in productivitiy, efficiency and market shares. To enable a Pan-European Access for SME on technology services for clean production, a network of premier KET Technology Centres with facilitated one stop shop access, offering SME multi-ket infrastructures and services across borders on pan-european level is generated, involving innovation consultants from the Enterprise Europe Network (EEN) being local = at the doorstep of EU`s manufacturing SMEs. Due to the disparity of KET TC in EU28, KET4CleanProduction (KET4CP) enables also a discourse with policy makers on RIS3 and the potential of cross-border collaboration to cover specific SME needs for clean production technologies. KET4CP starts with 12-premier KET TC and 7 EEN as an open innovation ecosystem, with a one stop shop access. KET facilitators support the SME in identifying their specific technology challenge for clean production, propose services and technologies based on innovation potential + need analysis. The fast, flexible services focus on the SME´s business case. After a pilot phase with 20 SME innovation projects/micro grants, the network is scaled up adding 17 KET TC and 21 EEN members, to reach a critical mass of CP technology deployment in SME. Targeted actions stimulate initial requests of >120 SME from > 10 EU MS and a total of 70 SME micro grant projects with min. 140 KET TC. 2 MEUR third party financing go to SME in total. 50 % are targeted for low to modest innovator regions. KET4CP delivers standard procedures / tools for KET TC transnational collaboration and joint service/shared infrastructure, based on business model scenarios stimulating KET TC to collaborate and share clients. KET4CP creates a sustainable platform, a win-win situation for all stakeholders with a high potential for scale up. The aim for 2022 is to have 100 KET TC and 180 EEN members with 1000 SME inquiries p.a.

Keywords: multi ket technology support for manufacturing smes in clean production throughout europe
Role of OligoSaccharyl Transferase enzymes in developmental signaling and congenital disorders of glycosylation (OSTers)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-06-01
End date: 2021-05-31
Duration (months): 24.0
Total project cost (EUR): 183473.28
EU funding (EUR): 183473.28
Participants: 1
Project status: CLOSED

Congenital disorders of glycosylation (CDGs) are genetic defects affecting the assembly and addition of asparagine (N)-glycans to proteins. N-glycosylation occurs in the endoplasmic reticulum by the Oligosaccharyl transferase (OST) complex. Mutations in components of OST complex are identified in CDG patients with broad clinical features. However, the mechanisms by which OST mutations cause phenotypic heterogeneity are not known. Moreover, in vivo studies on the precise role of individual OST components in animal development are lacking. In this framework, the goal of this proposal is to understand the function of OST complex during animal development, with a focus on their role in the regulation of developmental signaling pathways. The final aim will be to provide insights for deciphering some aspects of patients’ clinical features with OST mutations. This might lead to new frameworks for targeted therapeutic manipulation.

Keywords: congenital disorders of glycosylation n glycosylation bmp signaling
Forms of Labour: Gender, Freedom and Experience of Work in the Preindustrial Economy (FORMSofLABOUR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: United Kingdom,United Kingdom
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-09-01
End date: 2024-08-31
Duration (months): 60.0
Total project cost (EUR): 1666565.0
EU funding (EUR): 1611639.0
Participants: 2
Project status: SIGNED

The history of labour and its role in Europe’s preindustrial development has very largely been the history of adult men. FORMSofLABOUR seeks to put other workers in the picture, particularly women and servants, not simply by ‘adding them on’ but by showing how a full understanding of women’s work and of service offers a radical critique of existing approaches to work and to the idea of free labour. It focuses on England in the period 1300-1700 viewed in a comparative Western European perspective, and addressed these issues through three themes. (1) A revolutionary research technique which collects evidence of work tasks from court records to simulate a time-use study is used to explore the experience of work. This technique allows the work activities of women and men, young and old, employees and family members to be illuminated, with evidence of tasks, location and timing of work, creating an entirely new perspective on England’s early modern economy. (2) The theoretical underpinnings of the history of women’s work in the preindustrial economy are explored, reassessing key debates using interdisciplinary perspectives from economics and political science, as well as new archival evidence from themes 1 and 3. Gendered work patterns are viewed through the lens of freedom, rather than patriarchy, to create a step-change in our understanding of gender and work. (3) The issue of the extent to which labour was ‘free’ after the end of serfdom is interrogated through a careful examination of the range of forms of labour and the nature of labour laws, using a variety of archival evidence combined with a comparisons with serfdom and slavery, and the adoption of insights from development economics and anthropology. Together these interlocking themes create a new history of work in the economy which formed the background to grand narratives of Smith and Marx, arguing that with women and servants had been in picture, the story of economic development is transformed.

Keywords: work,labour,gender,freedom,labour laws,servants,household economy,youth,women,time use
Smart Bio Adhesives for the Wood Industry Powered by Machine Learning (Materialize.X)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: United Kingdom
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-08-01
End date: 2018-12-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

There is currently no scalable, sustainable and non-toxic adhesive for the engineered wood industry. Manufacturers are having trouble to cope with more restrictive regulations (EU REACH, EPA) on formaldehyde-based adhesives for engineered wood products. Some manufacturers are experiencing around 15% productivity loss due to recent regulation tightening. Current adhesives are toxic to humans and have been connected to health problems (i.e. cancer), and new bio-based adhesives such as soy or lignin are not available in large quantities, are too slow to react in the press and too expensive At Materialize.X, we have developed a biologically based adhesive that works within an industrial environment and is produced from an alternative feedstock, compliant with current regulations. On top of that, we offer a support software for optimization of production. Our software and hardware are tightly interconnected: by modelling the manufacturing process, we can integrate our adhesive into the production line much faster and cheaper than with current trial and error methods. Our company was founded in December 2016, and our team of 5 members has been able to successfully produce industrial-grade wood engineered pressed wood boards. To fund our innovation development and go to market we have already raised 350.000€ from business angels and are now closing a 450.000€ investment round. The adhesives market is valued at €50 billion/year and the engineered wood market at €250 billion euro/year (in 7 EU countries it adds to €20 billion). Our business model is based on dual revenue streams: SaaS fees for the software and a license fee for the use of our proprietary adhesive (UK patented, PCT to be submitted in May 2018). We expect Materialize.X to become the main bio-based adhesive in the EU and globally, pushing for formaldehyde phase-out and putting the European wood engineering industry at the global leader in eco-innovation.

Keywords: adhesive,engineered wood,optimization software,biocomposite,particleboards
Deciphering the mechanisms of antiviral RNA interference in mammals (UncoveRNAi)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-07-01
End date: 2021-06-30
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

Organisms such as plants, worms or insects rely on RNA interference (RNAi) to mount an antiviral immune response. On the other hand, it is widely believed that the type I interferon (IFN-I) pathway replaced antiviral RNAi as a primary line of defence against viral infections in chordates. However, recent work from multiple teams, including the host laboratory, has described a possible antiviral role for RNAi in cultured mammalian cells and in mice during infection with different RNA viruses. The importance of RNAi as an antiviral mechanism in mammals remains a matter of great controversy, in part due to a dearth of in vivo studies. In particular, the cell type(s) performing RNAi in vivo remains unknown, as is the relative importance of antiviral RNAi compare to the IFN-I response. I propose to decipher the mechanism and importance of antiviral RNAi in mice, by answering three main questions: 1) Where is antiviral RNAi happening? I will identify cell types implicated in antiviral RNAi using reporter viruses and permanent genetic marking of RNAi-competent cells. In parallel with these unbiased approaches, I will study antiviral immune responses in specific cell types likely to rely on antiviral RNAi, such as stem cells. 2) How is antiviral RNAi happening? I hypothesise that antiviral RNAi relies on truncated isoforms of Dicer expressed in specific cell types, and/or production of viral DNA as a means of boosting the RNAi response. I will explore both possibilities in detail. 3) What is the importance of antiviral RNAi? I will specifically ablate antiviral RNAi in cell niches that use this defence mechanism to assess its importance with respect to IFN-I. Overall, my work aims at dissecting antiviral RNAi pathways in mammals and assessing their in vivo significance. This work will provide answers to important questions in the field of antiviral immunity and will potentially open up new areas of research in human health.

Keywords: antiviral rna interference,cell intrinsic immunity,type i interferon,dicer,stem cells
Artificial Intelligence and Privacy Enabled Multi-Sensor Smart Cameras for 3D Analytics (SensorM3D)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Denmark
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-04-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: TERMINATED

GRAZPER presents a complete embedded solution for real-time, wide-area, 3D analytics for physical environments based on multisensor cameras. Our product – AI-PEVA 3D – intends to be an enabling tool for any entity that operates in the video camera market and monitoring of populated areas, generate large amounts of data and require compliance with GDPR legislation. Our customers are spread in three so called “Smart” segments: in Smart Cities, municipalities can plan roads and traffic better; in Smart Retail, shop owners can determine if people enter the store or just look, thus improving their marketing strategy; in Smart Security, surveillance agencies can follow suspicious movements and predict danger. To meet their demands, AI-PEVA 3D analyses video streams from real-time surveillance cameras based on Machine Deep Learning and Edge processing. The core of the technology is a re-identification system that transforms images immediately into quantized data, analyses it and reconstructs an anonymized 3D rendering, thus ensuring the privacy of any citizen caught on camera. The present SME Phase 1 proposal is perfectly aligned with the company´s strategy of maturing AI-PEVA 3D, namely the 3D multisensor camera and GDPR compliance to perform big data analytics with lower resources than the competition. At this stage, technical optimization according to the requirements of our potential customers and end-users, further demonstrations and certification will be our focus in Phase 2 project. This project will boost the growth of GRAZPER as a team and as a pioneer key player of multisensory smart cameras as Big Data tools for Smart Cities, Smart Retail and Smart Security segments.

Keywords: smart cameras,multisensor,3d analytics,gdpr complaint
Finding optimal size and location for wetland restoration sites for best nutrient removal performance using spatial analysis and modelling (OPTWET)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Estonia,New Zealand
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-04-01
End date: 2018-03-31
Duration (months): 36.0
Total project cost (EUR): 240507.0
EU funding (EUR): 240507.0
Participants: 2
Project status: CLOSED

Diffuse losses of nitrogen and phosphorus from agricultural areas contribute significantly to eutrophication of waterways, lakes, estuaries and coastal zones and water pollution is a growing and serious problem across much of the world. The role of wetlands in improving surface water quality is well known. The capacity of wetlands to improve water quality is dependent on a large number of parameters that have been widely studied, such as vegetation cover or type, water retention time, climatic variables, and also their size and spatial arrangement in the watershed. However, the question where wetlands should be located in agricultural catchments to achieve the most effective nutrient removal at the catchment level has not been clearly resolved. This project aims to determine the optimal sizing and location for wetlands in agricultural catchments to reduce nutrient (nitrogen and phosphorus) loads in catchments. The study consist of two parts performed on study areas with different landscape and climatic conditions. Firstly, potentially suitable wetland restoration/creation sites are identified by using high quality data and geospatial analysis techniques. Secondly, evaluation of the effectiveness of wetland nitrogen and phosphorus removal from surface waters at various potential locations indicated by the geospatial analyses under different hydrological regimes and land use scenarios will be done by using modelling with CLUES (Catchment Land Use for Environmental Sustainability model) and SWAT (Soil and Water and Assessment Tool). Important role in the study is also on using and integrating different datasets and modelling approaches.

Keywords: diffuse water pollution,wetlands,watershed management,water quality modelling,geospatial analysis
COllaborative CO-creation of web Applications on the CLOUD (COCOA CLOUD)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Finland
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2015, 2015)
Start date: 2015-12-01
End date: 2016-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

COCOA CLOUD is an innovative application development tool that will revolutionize the way complex web applications are built and user interfaces designed. Thanks to COCOA CLOUD web developers, designers and other business stakeholders will be able to work collaboratively on real web applications, avoiding the need of fake prototypes, and creating final advanced applications with just one click. COCOA CLOUD pioneers real-time co-creation of web applications, allowing the collaboration of all the project’s stakeholders (developers, web designers, analysts, project managers … even those without any web development technical background). COCOA CLOUD is the much awaited response to market needs for new development technologies that leverage the advantages of new iterative and collaborative methodologies such as Agile and DevOps. Thanks to this approach, our solution guarantees 30-50% reduction in the costs, and a 30% shorter time-to-market. Software is everywhere: the global software development market is expected to be €9.34B in 2016. Web applications are today the most popular technologies, being used by global corporations and SMEs in big data analytics platforms, banking applications, e-commerce, travel, manufacturing, etc: statistics show that 53% of the software developers are working with web-based user interfaces. This importance shows that this project will indisputably enhance the position of Europe in the global application development industry. The aim of the Phase 1 feasibility study is to ensure the technical viability of the project, plan the remaining integration, optimization and interoperability steps, assess of the commercial risks associated with expanding our geographical markets and users segments and analyze the Intellectual Property exploitation.

Keywords: software application development,agile development,web development,cloud collaboration,software prototyping
Biopolymers 13C tracking during fast pyrolysis of biomass-A 2-level mechanistic investigation (PYROCHEM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-01
End date: 2017-09-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

The Marie Skłodowska-Curie Actions (MCSA) proposal is the opportunity for Dr. Marion Carrier to reach a new level of understanding of fast pyrolysis mechanisms and improve the process and design of reactors by acquiring the necessary knowledge at a molecular-level and training using fractionation and isotopic characterization techniques, practical experience on micro-reactors and on larger scale laboratory reactors. It is proposed to use an integrated experimental and computational approach to provide molecular-level insights into pyrolysis chemistry by following the fate of 13C labelled lignocellulosic biopolymers, and subsequently to elucidate the main chemical events during the conversion of biomass. Empirical and mechanistic models will be combined to suggest a new kinetic model of fast pyrolysis. The thermal behaviour of individual unlabelled and labelled biopolymer carefully extracted will be investigated under controlled kinetic regime. The delineation and quantification of primary and secondary reactions will be achieved via the development of new devices for the collection of organic volatiles and via the implementation of spectrophotometric and spectrometric methods. For this, a combination of strong interdisciplinary expertise in several fields such as biopolymer chemistry, thermochemistry, aerosols trapping device fabrication, characterization of gas, liquid and solid products using spectrophotometric and spectrometry techniques is required. This multidisciplinary project will facilitate the commercialization of emergent renewable energy technologies such as fast pyrolysis via the optimization of bio-oil yields and quality, which is expected to offer alternative solutions in the co-production of fuels, high-value-added chemicals and energy, the main research activities of European countries members of the International Energy Agency.

Keywords: fast pyrolysis,mechanisms,biomass,13c labelling,extracted biopolymers