Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
TERAWI-LESS : A New Ultra High Speed Network (TERAWI-LESS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-02-01
End date: 2017-05-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

High-capacity wireless broadband communication systems(WBCS) are being ever more demanded by ICT and telecommunications applications that use massive amounts of data,such as big data analysis or high definition media streaming. The prospective data rate demand for WBCS will be 100 Gb/s in 2020,and current maximum data rates are 2.5 Gb/s. This need pushes the use of higher carrier frequencies that can handle high speeds in data transmission,like THzbased communications systems. Current THz antennas are custom-made to a specific network configuration, being expensive and only covering a narrow frequency band of interest for data transmission. Changes in the network specifications or in the frequency band used requires rebuilding the antenna’s most expensive parts; or building a new one entirely. TERAWI-LESS addresses this issue by offering three different THz-ranged high-gain antenna designs for different network configurations,which cover the whole frequency THz band of interest for data communications(not only a narrow one), with prototypes already in use in real conditions. These prototypes are already 28% cheaper than those available, and they must now be scaled-up to mass production,allowing even lower costs of at least 50% less than custom-made alternatives. Our target market is made up of telecommunications operators offering ground communication networks services, particularly through point-to-point WBCS. Specific objectives to be carried out in TERAWI-LESS project is the scaling-up and standardization of the production methods, as well as conducting risk and market analysis and initiating its commercialization. TERAWI-LESS project will be implemented by ANTERAL,a knowledge-based SME created in 2010 by telecommunications engineers from the Antenna Group of the Public University of Navarra (Spain), a research group with more than 15 years of experience on the field of antennas for mm-wave and THz-range and worldwide recognition from the scientific community.

Keywords: terahertz technology,antenna,data transmission networks,wireless broadband communication,mobile networks,wifi,wimax,umts networks,4g lte,tv broadcasting,ultra high definition television
Next generation renewable energy portfolio asset management based on predictive analytics (REWAM)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-08-01
End date: 2018-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Isotrol, as a specialist on ICT solutions for renewable energies, has identified a business opportunity of develop and take to market a new generation of portfolio asset manager based on analysing on the large amount of technical and economic data available. The consolidation of the renewable energies sector and the change of centre of gravity from technical towards financial and asset managers as the main players in the sector. These actors handle hundreds or thousands of energy generation facilities from a large diversity for sizes and technologies (Wind, Photovoltaics, Biomass, Hydro) that has purchased from promoters. The existing tools in the market are based on informational systems or scorecards for the main parameters of the facilities, but, in general, have not been able to take advantage of the complete digitization of the processes and the new techniques of BigData, predictive analytics and systems capable of learning that are capable of provide detailed insights of the portfolio for: a) detecting non-optimal production. b) selling energy strategy and c) O&M cost reductions. The solution is focused as a services (SaaS) for the management of the portfolio, providing specific information about these three areas. On-premise installation for some customers are also foreseen. This data driven predictive analytics over the detailed information of a renewable portfolio is expected to increase the revenue for asset manager in a 10%. Renewable energies is a key sector for EU economy that already employs over 1 million people and accounted for EUR 144 billion in 2014. The Renewable Energy Directive has the aim of making the EU world number one in renewables. European Commission has set the objective of 27% share of renewable energy for 2030. Growing rates for large (‘utility-scale’) renewable facilities are very consistent in main accessible markets (USA 51% in PV and 11% in wind; Europe, 12% and 5%, Latam 280% and 38%).

Keywords: renewable energies,asset management,predictive analytics,monitoring and control,ict software solution
Origin of genomic instability: Understanding the biological influence of inflammation in the initiation of pancreatic tumorigenesis (Onco-inflammation)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: TERMINATED

Inflammation is suspected to be the first step leading to cancer due to alcohol consumption or tobacco smoking between others. Little is known of how inflammation triggers genetic changes leading to tumorigenesis. Recently, I show that TGFb, a cytokine present during inflammation, is able to generate aneuploidy, polyploidy and plausible chromosomal rearrangements in breast cells. Such effects were mediated through the induction of the epigenetic reprogramming EMT. In view to understand how inflammatory signaling can affect the genome integrity, I design the project Onco-Inflammation, to study one of the most lethal cancer, the pancreatic ductal adenocarcinoma (PDAC), where therapeutic options are greatly limited. Using several mice models of pancreatitis, we will follow the establishment of genomic insults, and in particular focusing in whole genome doubling, nuclear envelope disruption and micronuclei. I will evaluate the genetic diversity present under pancreatitis and weigh the roles of the epigenetic re-programming Acinar-Dutual-Metaplasia as well as the oncogene KRAS, using high-resolution 3D imaging, as well as single cell CNV analysis (Aim1). I will also study the common pathways activated in newly aneuploid cells, in view to find some specific therapeutic target. (Aim2). Several pathways will be tested in an attempt to block cancer initiation and progression. Results will be tested and validated using human samples (Aim 3). At the Host Institution, I will greatly benefit and learn from the scientific guidance from my supervisor, expert in pancreas biology as well as experts in mitosis, genetic instability and bioinformatics. MSCA-IF will be instrumental to develop this initial hypothesis into deeper biological understanding the inflammation and cell plasticity’s roles on genomic instability and represent a crucial support to transition into an independent academic career.

Keywords: cancer,inflammation,genomic instability,mice models,pancreas,bioinformatic,copy number variation,cellular plasticity,micronuclei,whole genome doubling,translational medicine
All-sky search for continuous gravitational waves from neutron stars in binary systems (BINSKY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-05-01
End date: 2024-04-30
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: SIGNED

Gravitational waves from compact binary coalescences are now routinely detected, but other types of gravitational waves await to be discovered. Rotating neutron stars with an asymmetry around their rotating axis give rise to continuous waves, which differ from the already detected gravitational waves in their long duration (present during the whole observing runs) and expected weaker amplitude. Although many searches for continuous waves have been carried out, no detection has been achieved yet. The first detection of a continuous wave could be the next major discovery in gravitational-wave astronomy, probing the behaviour of matter at extreme conditions and the equation of state at densities above nuclear density that cannot be reached in any laboratory, the geometrical shape of neutron stars, and fundamental physics with tests of general relativity. This action aims to make the first detection of a continuous wave signal, searching for signals from unknown neutron stars in binary systems. More than half of the known neutron stars in the sensitive frequency region of the gravitational-wave detectors are part of binary systems. Neutron stars in binary systems may be more likely to have the asymmetries needed to emit detectable continuous waves, since they might be accreting matter from their companions which provides a natural asymmetry. This increases the chances of detecting a continuous wave signal, making all-sky searches of continuous waves from binary systems one of the most promising scenarios. All-sky surveys for continuous wave signals from neutron stars in binary systems are probably the most challenging search in gravitational-wave science. For this reason, they have been carried out seldom and at lower sensitivity compared to surveys from signals from isolated neutron stars, and with this project we want to address this deficiency. This project will be carried out at the Albert Einstein Institute in Hannover, within the research group lead by M.A. Papa.
DECISION ON OPTIMAL COMBINATORIAL THERAPIES IN IMIDS USING SYSTEMS APPROACHES (DocTIS)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Understanding health, wellbeing and disease
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Spain,Spain,Sweden,Sweden,United States,United Kingdom
Call: Systems approaches for the discovery of combinatorial therapies for complex disorders (H2020-SC1-2019-Two-Stage-RTD, 2019)
Start date: 2020-01-01
End date: 2025-12-31
Duration (months): 72.0
Total project cost (EUR): 6260050.0
EU funding (EUR): 6260050.0
Participants: 12
Project status: SIGNED

Immune-Mediated Inflammatory Diseases (IMIDs) are a group of common autoimmune diseases that include clinically heterogeneous disorders such as rheumatoid arthritis, psoriasis, psoriatic arthritis, Crohn’s disease, ulcerative colitis and systemic lupus erythematosus. Despite their clinical heterogeneity, IMIDs share a significant number of features at the molecular and cellular levels. Recently developed therapies targeting common key molecules of the immune system like anti-TNF agents, have collectively resulted in a significant improvement in the management of IMIDs. Still, the complete control of the chronic inflammatory process is rarely attained, and too many patients experience a poor response, if at all. This inefficacy has become a major economic burden and severely impacts on the wellbeing of many European citizens. The DocTIS projects aims to profoundly change this trend by identifying highly effective combinatorial therapies as well as the group of patients where this response will be optimal. Using the standardized samples from one of the world’s largest biobanks specialized in IMIDs, new molecular data will be generated using advanced high-throughput technologies including single cell RNA-seq. Systems biology methods will be applied to this unique clinical and molecular data to model the response to targeted therapies and predict what drug combinations will act synergistically and on which types of patients. After validation in a preclinical stage, the optimal combinatorial therapy will be tested in a group of patients with a positive biomarker profile. Using a basket trial, a new type of clinical trial design that incorporates molecular marker information, the DocTIS project will provide proof of concept of the utility of combinatorial therapy and personalized medicine for the effective control of disease activity in IMIDs.

Keywords: immune mediated inflammatory diseases,combinatorial therapy,biobank samples,high throughput molecular data,predictive models,personalized medicine
Full-equipped electric trailer to boost the implementation of efficient, eco-friendly and resilient last-mile delivery (FUTrailer)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-04-01
End date: 2019-06-30
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The last mile delivery sector is a significant contributor to the negative impact of transport in urban environments. Due to the explosion of the e-commerce home delivery together with the increasing number of cities banning motor vehicles in their centres, the last mile delivery is in urgent need of re-defining its current urban logistics model to increase their efficiency and cope with restrained traffic conditions. All companies operating in the last-mile sector have already started test different solutions for switching to cycle logistics; however, multiple deficiencies have been detected. The main challenge relies in increasing the cargo load that the bicycle can transport while ensuring its manoeuvrability and safety of both the cargo and the rider. At Nüwiel we have seized this opportunity and developed an electric cargo trailer, FUTrailer, that can carry big cargo loads (up to 300 Kg and 2m3) ensuring stability and safety for the user and the cargo. Our IP and the core technology is the patented intelligent riding system that ensures a perfect synchronisation between the trailer and the bicycle thus overcoming current stability and safety issues. FUTrailer offers the versatility needed to move around the city, as it incorporates an automatic switch between cycling and walking mode: the trailer can be used as an e-handcart in pedestrian areas and even inside buildings. FUTrailer will positively impact European cities enabling a smooth implementation of cycle logistics in the last mile delivery. With almost 13,000 FUTrailers in the market in 2023, we expected to substitute 292 million Km of motor vehicles saving up to 91 million tonnes of CO2. This will allow a reduction of up to 30% of urban traffic congestion and 40% air pollution and a decrease in traffic noise by 10. FUTrailer will also boost the growth of Nüwiel with revenues of €28 million by 2023 and the creation of up to 60 new job positions.

Keywords: urban mobility,lat mile operations,intelligent ride system,clean transportation solution,safe and secure transportation,multimodal trailer,flexible trailer
New Strategy for Re-Naturing Cities through Nature-Based Solutions (URBAN GreenUP)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Fighting and adapting to climate change
Action type: Innovation actions
Countries involved: Italy,Italy,Spain,Germany,Spain,Italy,Spain,Spain,Spain,Türkiye,China,Colombia,Türkiye,United Kingdom,United Kingdom,Viet Nam,Portugal
Call: Demonstrating innovative nature-based solutions in cities (H2020-SCC-NBS-2stage-2016, 2016)
Start date: 2017-06-01
End date: 2023-05-31
Duration (months): 72.0
Total project cost (EUR): 14802476.25
EU funding (EUR): 13970642.25
Participants: 27
Project status: SIGNED

Urban GreenUP aims at obtaining a tailored methodology (1) to support the co-development of Renaturing Urban Plans focused on climate change mitigation and adaptation and efficient water management, and (2) to assist in the implementation of NBS in an effective way. NBS classification and parametrization will be addressed and some resources to support decision making will be established as part of the project activities. A large scale and fully replicable demonstration action of NBS accompanied by innovative business models will provide evidences about the benefits of NBS contributing to the creation of new market opportunities for European companies, and fostering citizen insight and awareness about environmental problems. Three European cities will assume the demos as front-runners (Valladolid, Liverpool and Izmir), other set of two European cities will act as followers to strengthen the replication potential of the results (Ludwigsburg and Mantova) and finally three non-European cities (Medellín, Chengdu and Quy Nhon) will allow to identify the market opportunities for European companies out of Europe and fostering the European leadership in NBS implementation at global level. URBAN GreenUp also aims to: fostering the creation of a global market and EU international cooperation; deploy a wide Exploitation and Market deployment procedure for NBS solutions & deploy an Impact-based Communication and Dissemination strategy.

Keywords: renaturing cities,nature based solutions,demonstration,monitoring,replicability and transferability,up scaling,market deployment,global market and international cooperation,dissemination
COFUND BIST POSTDOCTORAL FELLOWSHIP PROGRAMME (PROBIST)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Fellowship programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Spain,Spain
Call: Co-funding of regional, national and international programmes (H2020-MSCA-COFUND-2016, 2016)
Start date: 2017-12-01
End date: 2023-11-30
Duration (months): 72.0
Total project cost (EUR): 12956400.0
EU funding (EUR): 6478200.0
Participants: 6
Project status: SIGNED

PROBIST is an ambitious programme offering 61 three-year fellowships to foster excellence in multidisciplinary postdoctoral research at BIST´s constituent research centres and associated partner institutions (hospitals, private companies, technology centres, and other academic institutions), which will provide opportunities for collaborations and secondments, training, networking activities and other actions to complement the research activities and professional development of the fellows. The PROBIST proposal is presented by the Barcelona Institute of Science and Technology (BIST) as beneficiary. BIST, a private non-profit foundation, was created in 2015 as an initiative of the Catalan government to bring together six Excellent Flagship Catalan research centres that already had a track record of working together: the Centre for Genomic Regulation (CRG), the Institute of Photonic Sciences (ICFO), the Institute of Chemical Research of Catalonia (ICIQ), the Catalan Institute of Nanoscience and Nanotechnology (ICN2), the Institute for High Energy Physics (IFAE) and the Institute for Research in Biomedicine (IRB Barcelona). The COFUND Postdoctoral Programme goals are: 1. To contribute towards improving conditions for carrying out high-quality research at the research centers and to increase its international visibility. 2. To offer coordinated postgraduate programs of excellence with international impact. 3. To build a critical mass to multiply the capacity of the research centers in different fields, such as knowledge transfer, scientific and technological platforms and talent attraction. 4. To cooperate with scientific institutions, companies, individuals and public or private entities to fulfill these aims.

Keywords: postdoctoral training,biosciences,nanotechnology,physics,chemistry,photonics
Coherent Optical Parallel Computing (COPAC)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Italy,Israel,Italy,Belgium,France
Call: FET-Open research and innovation actions (H2020-FETOPEN-1-2016-2017, 2017)
Start date: 2017-11-01
End date: 2021-04-30
Duration (months): 42.0
Total project cost (EUR): 2993640.0
EU funding (EUR): 2993640.0
Participants: 7
Project status: CLOSED

COPAC is a transformative novel area in computing both because of the technology, coherent information transfer by ultrafast laser addressing of engineered quantum dots, QD, arrays and because of the specialized parallel processing of large amounts of information. We will make foundational experimental, theoretical and algorithmic innovations to demonstrate a new technological paradigm for ultrafast parallel multi-valued information processing. We aim to develop a ground-breaking nonlinear coherent spectroscopy combining optical addressing and spatially macroscopically resolved optical readout to achieve unprecedented levels of speed, density and complexity. Two key high-risk / high-reward pioneering elements are the quantum engineered coherent concatenation of units and the multidirectional optical detection. Experimental demonstrations on tailored multilayer QD arrays of increasing complexity, integration into a device and novel hardware and matched compilers will be delivered. Preliminary experimental demonstrations of the response of solutions and of QD films are available as is the validation of logic operation in parallel. We use the dynamic response of the designed QD arrays to implement novel paradigms for parallel information processing. The discrete quantal level structure of nanosystems provides a memory at room temperature. Input will be provided simultaneously to all the levels by broadband laser pulses and the dynamical response will implement the logic in parallel. Disorder and environmental fluctuations are not detrimental because controlled level broadening is essential for the simultaneous multidirectional optical readout at the macroscopic level. The long term vision of COPAC is the application of atomic and molecular state resolved controlled quantum dynamic processes towards information processing. Within this our targeted breakthrough is a novel prototype device for parallel logic engineered to industry standards and with suitable compilers.

Keywords: nonlinear ultrafast optical spectroscopy,coherent energy transfer,spatial resolution of emission,quantum dot array,multivalued parallel logic,rebooting computing,non von neumann architectures