Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
European 450mm Lithography and Metrology Development for Advanced Patterning (E450LMDAP)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Electronic Numerical Integrator and Computer
Action type: Collaborative project
Partnership: ENIAC (Art-185)
Countries involved: Netherlands,France,Israel,Germany,Belgium,Germany,Netherlands,France,France,France,France,United Kingdom,Netherlands,Netherlands,Germany,Belgium,Germany,Germany,Germany,Germany
Call:  (ENIAC-2013-2, 2013)
Start date: 2014-10-01
End date: 2017-10-01
Duration (months): 36.0
Total project cost (EUR): 459306457.73
EU funding (EUR): 68895968.66
Participants: 42
Project status: CLOSED

The overall goal of the E450LMDAP project is to develop 450 mm lithography and metrology modules and tools and to initiate distributed pilot line activities over the 450 mm lithography and metrology tool platform eco system. These pilot line activities will go down to the pilot lines of the lithography tool and the related (sub-)systems and components supply chain and metrology tool suppliers. In addition, also early 1x node patterning module qualification at the imec’s pilot line will be part of the project. Lithography, metrology and deposition equipment performance suited for 450 mm will be demonstrated, interconnected with holistic methodologies to the 450 mm pilot line at imec which is equipped with European systems. The project will complement the engagement of the European semiconductor equipment industry in the 450mm wafer size transition that started with the ENIAC JU EEMI450 initiative and proceeded with subsequent projects funded with public money, amongst others NGC450, SOI450, EEM450PR and E450EDL which will result into first critical process module availability in the imec pilot line. The consortium comprises 44 members from 7 different European countries with SMEs and research institutes and also IDM as end users. The project is organized in three technical work packages and a work package on management and coordination. The main objective in the work package on lithography is to develop and to have prototyping activities comprising amongst others wafer stage, wafer handler, optics, electronic as well as preliminary tool system qualification. In the dedicated work package on metrology 450mm metrology tool types will be developed for wafer and mask platforms as well as a holistic metrology data hub for advance lithography data management and fab. Finally, in the work package on advanced patterning a selection of critical N10 layers, which are currently under development at 300mm wafer sizes, will be transferred to an early 450mm lithography platform.

Keywords: lithography and metrology for 450mm wafer processing
Strengthening of the MagBioVin Research and Innovation Team for Development of Novel Approaches for Tumour Therapy based on Nanostructured Materials (MAGBIOVIN)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Serbia
Call:  (FP7-ERAChairs-PilotCall-2013, 2013)
Start date: 2014-05-12
End date: 2019-05-11
Duration (months): 60.0
Total project cost (EUR): 2795860.0
EU funding (EUR): 2243828.0
Participants: 1
Project status: CLOSED

Through the realization of MagBioVin project, the Institute of Nuclear Sciences “Vinca”, University of Belgrade (Serbia) receives important community support to upgrade its capacities related to the highly specialized research on activated magnetic nanoparticles (MNP) and radionuclide labeled magnetic nanoparticles for application in biosciences, pharmacy and medicine. This is planned to be realized by a set of comprehensive actions, such as engagement of eminent expert in the field (ERA Chair holder), bringing experimental facilities up to the most advanced EU-competitive level, cutting-edge trainings in reputable EU research institutions and intensive dissemination towards ERA, Universities and stakeholders. The Project foresees the key role of ERA Chair holder in improvement of organizational structure, research excellence and especially in communication with stakeholders. Organization of seven dedicated international workshops led by EU experts in the field, six extensive training programs for MagBioVin team members and the accent on intensified international collaboration, are few of the activities anticipated through Project implementation. These are designed to set solid foundations for a final goal: to rise both human and experimental capacities of the “Vinca” Institute to the level that ensures considerable scientific and technological impact within ERA and its ability to compete with leading EU research institutions on an equal basis.

Keywords: nanotechnology,magnetic nanoparticles,radiopharmaceuticals,magnetic hyperthermia,mri
Nietzsche's Reading of Emerson. A Genetic Study (EMERSON-NIETZSCHE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2013-IEF, 2013)
Start date: 2015-03-03
End date: 2017-03-02
Duration (months): 24.0
Total project cost (EUR): 261384.6
EU funding (EUR): 261384.6
Participants: 1
Project status: CLOSED

Ralph Waldo Emerson played a fundamental role in the development of Friedrich Nietzsche’s philosophy. There was no author whom Nietzsche admired more and longer than Emerson. Nietzsche’s personal copies of Emerson's works provide us with strong and reliable evidence of his deep intellectual relation with the American essayist. The pages of these books are covered with a lot of signs of reading, from underlinings, exclamation marks, question marks, and dog-eared pages to numerous annotations and philosophical comments written in the margins. So far these signs of reading have never been taken into consideration by scholars in their studies of the relation between the two authors. Aim of the project is a philosophical study of Emerson’s influence on Nietzsche, based for the first time on a careful reconstruction and exhaustive analysis of the traces of their relation. The historical-philological approach to Nietzsche's philosophy introduced by Mazzino Montinari and then adopted by many scholars all over the world will be complemented with the methodology of genetic criticism developed at ITEM (CNRS/ENS, Paris) and successfully applied by Paolo D’Iorio to Nietzsche’s philosophy. This project can significantly reinforce European leadership in the research on Nietzsche and, more generally, in philosophical research. Moreover, the information technology tools elaborated by ITEM for the execution of genetic studies will enhance both impact and visibility of the research results.
Landscape connectivity for Cat species: transcending structures, scales and climates (CONTRASST)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2013-IOF, 2013)
Start date: 2015-01-01
End date: 2017-12-31
Duration (months): 36.0
Total project cost (EUR): 242049.6
EU funding (EUR): 242049.6
Participants: 1
Project status: CLOSED

Anthropogenic pressures drive global biodiversity loss. The loss of landscape connectivity, further exacerbated by climate change, is a key driver of species decline. Hence, it is crucial to identify key elements that ensure landscape connectivity across landscapes and scales. Several challenges in this context include insufficient knowledge of 1) species’ eco-physiology across landscapes and ranges, 2) the mechanisms driving migration pulses, 3) how local-scale processes (animal movements) translate to large-scale and longer-term patterns (species’ distributions and range shifts), and consequently, 4) the spatial scale(s) at which connectivity needs to be maintained to mitigate climate change effects on species. These issues are best addressed through comparative studies across a range of landscapes and climates, using umbrella species requiring large areas. Using lynx species in North America and Europe as models, this project will establish an integrative approach across scales to predict functional connectivity for wild felids, specifically by a) determining eco-physiological thresholds to environmental stressors and mechanisms driving dispersal pulses between peripheral and core populations, b) investigating the influence of climate and habitat fragmentation on the genetic structure and eco-evolution of these species, and c) identifying how local-scale processes translate into large-scale patterns of connectivity, species’ distribution and range shifts. Ecological and environmental data across continents will be integrated using groundbreaking eco-physiological and landscape genetics tools, and dynamic simulation modelling (using the novel individual-based model RangeShifter). Spanning 3 years under a careful management plan to ensure feasibility of all 3 chapters, this transdisciplinary project will provide valuable insights and conservation guidelines on how to maintain large-scale connectivity for umbrella species across fragmentation and climate scenarios.

Keywords: v201 terrestrial ecology - land cover change,v304 conservation biology - ecology - genetics,biodiversity loss,continental-scale approach,carnivore ecology,population dynamics,eco-physiology
The Braided Side of the Earth: modelling the long-term morphological impact of dams on the gravel-bed braided rivers of New Zealand to support restoration of the heavily-impacted European rivers. (BRAIDSIDEEARTH)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2013-IOF, 2013)
Start date: 2015-04-01
End date: 2018-03-31
Duration (months): 36.0
Total project cost (EUR): 260121.6
EU funding (EUR): 260121.6
Participants: 1
Project status: CLOSED

The present three-year project aims at predicting and quantifying the impact of dam construction and operation on highly dynamic, multi-thread river systems through the development of a novel, physically-based numerical morphodynamic model, which can be used as a decision support tool in river management and restoration. Gravel-bed rivers with braided and transitional morphologies were once common in alpine-piedmont regions of Europe, providing key services to the human society and sustaining biodiversity. Only few of them still preserve their unique fluvial landscape, because of multiple anthropic effects in the last century which caused narrowing, incision and overall transformation of river styles and functions. One of the main causes are artificial reservoirs, which alter flow and sediment regimes, thus impacting the hierarchy of controlling variables of river systems. Due to lower anthropic pressure, the gravel-bed rivers of New Zealand have experienced much a lower degree of alteration, and are thus an ideal benchmark to investigate restoration strategies that are a priority requirement of several EU Directives for the impacted European rivers. To this aim, during the outgoing phase at NIWA (Christchurch, New Zealand) I will investigate such benchmark by analysing the evolution of natural and dam-impacted New Zealand and European gravel-bed, multi-thread rivers, acquiring new expertise in river geomorphology. At NIWA I will use by my modelling background to develop a numerical model able to address the key controlling interactions for the study river systems, namely among flow, morphodynamics and riparian vegetation, at decadal time scales. My expertise in morphological modelling will be complemented at the return host (Univ. of Trento, Italy). Besides completing and diversifying my knowledge, the project will finally allow for an innovative, model-based quantitative assessment for the restoration of dynamic, multi-thread rivers affected by dam operations.

Keywords: gravel-bed braided rivers,river morphodynamics,dams,numerical modelling,river restoration.
Testing and up scaling of technology developed under the SOLNOWAT FP7 Project which developed a competitive 0 GWP, dry, atmospheric pressure etching process for use in manufacture of PV solar cells (DEMOSOLNOWAT)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Demonstration Activity
Action type: Collaborative project
Countries involved: Germany,France,Ireland
Call:  (FP7-SME-2013, 2013)
Start date: 2014-04-01
End date: 2016-04-30
Duration (months): 25.0
Total project cost (EUR): 2400098.0
EU funding (EUR): 1295077.0
Participants: 3
Project status: CLOSED

Following on the successful results of SOLNOWAT project that commenced in September 2011, this project will focus on up scaling and demonstrating the novel technology that was developed for the photovoltaic manufacturing industry under the first FP7 project. The technology developed and proven in the SOLNOWAT project serves to reduce the water consumption of the cell manufacturing process, focussing on the etching steps, high throughput technology and specific process control - this follow on project will act as a stepping stone in getting the innovations from the "lab to the fab". Under this project specific industrial scale prototype equipment will be built by the participating SMEs and the technology will be demonstrated and tested i.e. the equipment will feature a dry etching tool with high volume/ high throughput system, integrating specific process control. Given the turmoil that exists in the solar industry at this time the funding of this prototype testing would be very difficult without European Funding. Up to 68% of all cells made in 2011 came from China or Taiwan, innovation & significant cost reduction is required if Europe is again to become a player in the PV manufacturing industry.

Keywords: atmospheric pressure dry etching high throughput prototype building testing and further market validation
Cost effective Direct to Eye prosthesis SMART Guidance System (D2EYE)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Germany,Spain,Germany,Italy,Germany,United Kingdom,Germany
Call:  (FP7-SME-2013, 2013)
Start date: 2014-02-01
End date: 2016-01-31
Duration (months): 24.0
Total project cost (EUR): 1417372.93
EU funding (EUR): 1083919.21
Participants: 10
Project status: CLOSED

Approximately 800,000 hip operations are performed annually in Europe. In 56% of these operations, the components, in particular the cup, are not aligned correctly; this misalignment alters the biomechanics of the system, such that excessive wear of the cup occurs. The subsequent reduction in implant lifespan will affect ~450,000 European citizens, an average of 30,000 per year. In financial terms, the annual cost to European healthcare institutes is in the region of €426m euros, in addition to the increased likelihood of re-revision and associated aftercare costs. There are two types of navigation system currently on the market: (1) Image based which uses CT data to generate 3D preoperative images, and (2) Image-free systems which rely on kinematic data or point-clouds acquired intra-operatively to generate a 3D reconstruction that can be explored during the operation on a computer screen. Both systems have demonstrated improved accuracy over manual surgery. However, current systems entail a large initial cost (~€250K) with high maintenance costs; in addition, most systems take an extra 15 minutes to setup, using valuable theatre time. The D2Eye project will develop a simple to use, low cost, fully mobile guidance system with reduced set up time. The guidance system will allow the surgeon to position the cup accurately allowing for optimum range of movement and as a result will prevent premature failure of the implant normally associated with misalignment. This will be done using a series of electronic orientation units built in to the surgical instruments which will give their position in free space. The information from the units will be projected in front of the surgeon’s eye in real time, allowing them to identify the correct cup implantation position; such a system will enable implant lifetimes to be extended beyond the current average 15 year lifespan, significantly reducing the burden on the healthcare system.

Keywords: smart guidance system,built-in heads-up display,unobtrusive view,hip surgery
A Novel Microwave-Enhanced Superheated Steam Process for High Performance Drying of Hygroscopic Polymers (HIPERDRY)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SME associations
Action type: Research for the benefit of specific groups
Countries involved: Germany,Germany,Spain,Italy,France,Germany,Netherlands,Spain,Germany,United Kingdom,Germany,Spain
Call:  (FP7-SME-2013, 2013)
Start date: 2013-10-01
End date: 2016-12-31
Duration (months): 39.0
Total project cost (EUR): 3372430.9
EU funding (EUR): 2378000.0
Participants: 12
Project status: CLOSED

The principal objective of the HiPerDry project is to create a significant advance over the state of the art in hygroscopic polymer drying technology. A three year development programme which will culminate in the testing and demonstration of a prototype hygroscopic polymer drying system is proposed. The resulting combined microwave and super-heated steam drying (MW-SHSD) system will boast the following advantages: 30 to 50 % reduction in process energy costs as well as run time, the ability to efficiently dry heat-sensitive hygroscopic polymers (especially biopolymers) without the risk of material degradation and the built-up of knew know-how about the drying and processing of heat-sensitive bioplastics. Therefore the competitiveness of the SME-members of the SME-AGs will be significantly risen and thresholds for the processing of bioplastics will be lowered. The five SME-AGs from five different SME states and two SMEs from two different EU States in the project, together form the ideal trans-national partnership to exploit and disseminate the foreground intellectual property developed in the project for the benefit of hygroscopic polymer-processing SMEs right across Europe. However, lacking both capability and capacity to develop the proposed MW-SHSD technology, we have a need to out-source the necessary R&D. The Research for SME-Associations funding instrument provides us with the perfect opportunity to employ our preferred RTD partners to carry out the planned work programme. In return for paying the RTDPs for their work, the SME-AGs will retain all the rights to the Foreground Intellectual Property developed in the HiPerDry project. For its investment of €2.38 million in the HiPerDry project, the European plastics processing industry will earn a financial return of €158.8 million in turnover, see the creation of 798 new jobs in the industry and witness an increase in the global competitiveness of thousands of hygroscopic polymer-processing SMEs across Europe.

Keywords: microwave,superheated steam,process data of biopolymers and hygroscopic polymers,best practice guidelines
Novel tumor-selective lethal miRNAs for the treatment of head and neck cancer (MIRACLE)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Netherlands,Israel,Germany,Netherlands,Germany,Netherlands
Call:  (FP7-SME-2013, 2013)
Start date: 2013-10-01
End date: 2016-10-31
Duration (months): 37.0
Total project cost (EUR): 1521353.6
EU funding (EUR): 1172000.0
Participants: 9
Project status: CLOSED

MiRacle focuses on the development of a therapeutic formulation for the treatment of head and neck cancer. Head and neck cancer contributes to approximately 5% of all cancers in the Western world. Unfortunately the majority of H&N cancer patients present with advanced stages of disease. These patients frequently develop locoregional recurrences, distant metastasis and/or second primary tumors resulting in 5-years survival rates of less than 60% The development of novel anti-cancer agents to improve outcome is therefore urgently awaited. The goal of MiRacle is the advancement of a therapeutic tumor-killing miRNA formulation towards the clinic by combining two innovative technologies, i.e. therapeutic miRNA and head and neck tumor specific targeted drug delivery. Such a project requires (1) expertise in the therapeutic application of miRNA (InteRNA) and knowledge on the synthesis of biochemical active miRNA (Biospring), (2) knowledge of drug formulations to deliver the therapeutic miRNA into humans (IC) and understanding the synthesis of complex drug formulations (Polymun), plus (3) in-depth knowledge of the therapeutic indication, e.g. H&N cancer (VUmc) and skilfulness in toxicity tests that are required for RNA based drug registration (LPT). We believe that this project encompasses all parties that are required to successfully bring a tumor killing miRNA towards registration for first in human testing.

Keywords: head & neck cancer mirna drug delivery drug formulation
Fast, cost-effective, user-friendly point of care (POC) instrument for detection of respiratory pathogens, including Streptococcus pneumoniae (RESPOC)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Spain,Germany,Germany,Italy,United Kingdom
Call:  (FP7-SME-2013, 2013)
Start date: 2013-12-01
End date: 2016-08-31
Duration (months): 33.0
Total project cost (EUR): 1469406.81
EU funding (EUR): 1102097.27
Participants: 8
Project status: CLOSED

Molecular techniques such as PCR (polymerase chain reaction) are becoming increasingly used for the detection of respiratory pathogens, due to their high accuracy and relatively fast turnaround time (hours). Their utilization can result in early and specific treatment, contribute to better patient outcomes and reduce length of hospital stay. However, implementation of rapid molecular diagnostics remains limited to large, centralised laboratories which can afford the requirements of dedicated PCR laboratory space, specialized personnel and costly equipment and consumables. Even in central laboratories, timely diagnosis may be undermined by delays during sample transport to the setting and batching practices oriented to save consumables. There is a need for a fast, cost-effective, user-friendly molecular diagnostic point-of-care (POC) instrument for near-patient use at small to medium size hospitals, and decentralized clinical laboratories. The RESPOC platform will be a novel solution designed to detect bacterial and viral respiratory pathogens in less than one hour. Based on the development of DNA extraction and DNA amplification methods integrated into a low-cost microfluidic lab-on-a-chip (LoC) consumable, the platform will deliver results automatically by insertion of the disposable LoC into a small footprint reading instrument. Initially it will identify the target respiratory pathogens Streptococcus pneumoniae (pneumococcus) and Bordetella pertussis. Pre-clinical validation and demonstration of the RESPOC instrument will be performed at the facilities of the RTD hospital participant and at the facilities of the SME end-users to ensure adequate diagnostic performance and usability.

Keywords: molecular assay,molecular analysis,dna amplification,fluorescence,lab-on-a-chip (loc),streptococcus pneumonia,respiratory pathogens