Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Larval quality in oyster hatcheries: Effects of ocean acidification, temperature change and food availability on reproductive success and survival of the European flat oyster (LARVDEVOPTI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Sweden
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-08-16
End date: 2013-08-15
Duration (months): 24.0
Total project cost (EUR): 193266.4
EU funding (EUR): 193266.4
Participants: 1
Project status: CLOSED

The proposed research will investigate the effects of biological and physicochemical conditions on growth and development of the European flat oyster (Ostrea edulis) throughout its life cycle. Specific research objectives for this project are: 1. determine current causes of hatchery instability in broodstock conditioning and larval productivity, including potential effects of ocean acidification and temperature change on larval development in O. edulis; 2. optimize ecophysiological conditions for O. edulis larval development in a commercial-scale hatchery to allow sufficient production of spat for expansion of the flat oyster aquaculture industry; 3. identify coastal grow-out sites on the Bohusian coast (at least 3) that are suitable for aquaculture operations in order to optimize the growth of O. edulis to marketable size. The research links together multiple research groups and industry partners in optimizing the cultivation of flat oysters. Studies will utilize established infrastructure at the Sven Lovén Marine Sciences Center of Gothenburg University, the Danish Shellfish Centre, and the commercial hatchery Ostrea Sverige. The Applicant will be working with researchers at these institutions to apply interdisciplinary expertise to the project objectives. This proposal combines aspects of developmental biology, marine ecology, chemical and physical oceanography, and geography, and the application of these fields to answering key questions about oyster larval development and improvement of aquaculture processes. A lack of understanding of factors affecting larval and juvenile survival currently curtails hatchery production of O. edulis in Sweden, thereby impeding expansion of a European flat oyster aquaculture industry in northern waters. Data derived from the project will be relevant to the effects of ocean acidification on natural populations, while also ensuring successful hatchery production to meet European market demand for high-quality cultured shellfish.

Keywords: developmental biology,animal embryology,animal growth,agricultural products,animal ecology,applied ecology,agricultural science (climate change),aquaculture,aquaculture technology,stress (aquaculture)
Spectrum of the planar AdS/CFT correspondence (SPECTRUM OF ADS/CFT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2011-10-01
End date: 2014-09-30
Duration (months): 36.0
Total project cost (EUR): 229056.8
EU funding (EUR): 229056.8
Participants: 1
Project status: CLOSED

This project aims to formulate the full solution to the spectral problem of the planar AdS/CFT correspondence. This will be achieved in three steps. Firstly, I will subject the recently proposed set of spectral equations (TBA equations) for the planar AdS/CFT correspondence to extensive tests and, if necessary, modify them. Secondly, I will develop new powerful tools to facilitate the computation of the energies/dimensions of the physical states from the TBA equations. This should also give a handle on the origin of the underlying integrable structures. Finally, I will attempt to motivate the spectral equations for each of the constituent theories separately. This will furnish a proof of the planar AdS/CFT correspondence as far as the spectral problem is concerned and is expected to provide a profound insight into the dynamical degrees of freedom of the gauge and string theories. The proposed research will significantly advance the state-of-the-art of the AdS/CFT correspondence and of exactly solvable quantum field theories.

Keywords: quantum field theory,mathematical physics,ads/cft correspondence,integrability in gauge and string theories,non-perturbative methods in gauge and string theory
New chemical tools for profiling protein lipidation in cancer (LIPOPROT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-07-17
End date: 2013-07-16
Duration (months): 24.0
Total project cost (EUR): 209092.8
EU funding (EUR): 209092.8
Participants: 1
Project status: CLOSED

This project aims to develop chemical probes and technologies that will enable for the first time high-throughput analysis and exploration of the complex biological networks involved in protein lipidation. These chemical tools will be applied to mapping the changes in lipidation that occur in the proliferation and survival of cancer cells, with the ultimate objective of identifying and validating cellular mechanisms that can be targeted for future chemotherapy. The proposed work is multidisciplinary, combining organic synthesis with proteomics and cell biology. As such it lies at the cutting edge of chemical biology, and will permit the applicant to gain skills and independence to found an independent group in chemical biology.

Keywords: organic chemistry,chemical biology,cell biology,chemical proteomics,protein lipidation
Perturbations, stability and Hawking radiation of higher dimensional black holes (STABILITYHAWKING)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2011-09-01
End date: 2013-08-31
Duration (months): 24.0
Total project cost (EUR): 202892.8
EU funding (EUR): 202892.8
Participants: 1
Project status: CLOSED

We propose a detailed investigation of the gravitational stability and emission of Hawking radiation of diverse higher-dimensional black hole solutions motivated by string theory and higher dimensional gravity. The applicant aims at the complete classification of higher-dimensional black holes according to their gravitational stability. In addition, we plan to make further investigation of possible correlations between gravitational and thermodynamical instabilities in such systems, and, to check if there is a correlation between gravitational instability and existence of closed time-like geodesics.

Keywords: black hole,stability,hawking radiation,perturbations,brane,string theory,gravity
Spectral analysis of graph-coupled systems (GRAPH-COUPL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2012-01-01
End date: 2012-12-31
Duration (months): 12.0
Total project cost (EUR): 132968.4
EU funding (EUR): 132968.4
Participants: 1
Project status: CLOSED

The analysis of thin branched structures has become very popular in Mathematical Physics during recent years. One reason is the increasing technological feasability of manufacturing nano-structures at an atomic level, making a detailed quantum mechanical analysis of the problem necessary. Thin branched structures occur e.g. in micro-electronics or in opto-electronics; and a theoretical analysis is necessary in order to understand the behaviour of such media or to engeneer materials with certain properties. One is for example interested whether a material conducts or transmits light or not, e.g. semi-conductors or photonic crystals. The project aims in a mathematical analysis of thin branched structures providing a large class of (at least approximatively) solvable models. One goal of the project is to what extend thin branched structures can be understood by their decomposition into simple building blocks according to the underlying network structure. By this decoupling method, we want to tackle open problems in Mathematical Physics like the extended states conjecture, i.e., the question whether a randomly perturbed periodic medium still allows transport for small perturbations. Another goal of the project is the question whether thin branched structures and their properties can approximately be described by the pure one-dimenional limit, the underlying network structure. Olaf Post, the researcher of the proposal, is an expert on the theory of thin branched structures in the zero-thickness limit. Marco Marletta, the scientist in charge, is a recognized top-level specialist in the mathematical analysis of partial differential operators and their spectral properties and in operator theory. Our project brings together these two very active areas of Mathematics, and aims in providing concrete mathematical models which are useful in engineering nano-structure devices.

Keywords: mathematics,differential equations,functional analysis,spectral theory of pdes,dirichlet-to-neumann operator,coupled systems,graph-like structures,boundary triples,mathematical physics
Top Partners at the LHC (PARTNERS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2012-04-01
End date: 2014-03-31
Duration (months): 24.0
Total project cost (EUR): 213390.4
EU funding (EUR): 213390.4
Participants: 1
Project status: CLOSED

The objective of this proposal is a thorough study of the minimal LHC phenomenology of partners of the top quark and other standard model particles. The existence of these partners is a prediction of many approaches to solving the hierarchy problem: that is, the question of why the mass of the Higgs boson is small compared to fundamental scales in physics. In essence, the role of these new partners is to cancel quantum corrections to the Higgs mass which arise from standard model particles. The top quark is responsible for the largest correction to the Higgs mass in the standard model, and therefore the mass of its partner is expected to be well within the experimental reach of the LHC. Theorists have proposed a variety of models which solve the hierarchy problem. Some of these models have been studied in detail but others have not. This proposal will fill the holes in our knowledge of what physics at the LHC will look like if there is a solution to the hierarchy problem in nature. The approach will be very general, focusing on effective field theories which incorporate approximate cancellations of the corrections to the Higgs mass. We will identify and describe experimental signatures of the models and validate these signatures by numerical simulations. We will also investigate the question of whether new developments in the understanding of scattering amplitudes open new methods for discovering the new symmetries which are usually required to cancel the quantum corrections. In addition to the value of this research, the proposal will contribute to the competitiveness of European science by transferring knowledge of particle physics from the US to Europe. This knowledge transfer will occur through mentoring students; teaching courses and public outreach activities. The researcher will move from the US to begin a long-term career in physics research in Europe.

Keywords: quantum field theory,particle physics,lhc phenomenology
Functorial and algebraic methods in the study of systems of linear partial differential equations. (FUNALGPDE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2011-10-01
End date: 2013-09-30
Duration (months): 24.0
Total project cost (EUR): 160592.0
EU funding (EUR): 160592.0
Participants: 1
Project status: CLOSED

A first aim of the research project FUNALGPDE is to let the applicant get in a long contact with the Research Institute for Mathematical Sciences, Kyoto, Japan. At RIMS Dr Morando will learn new interdisciplinary methods in the algebraic study of differential equations and their applications to other fields of mathematics (representation theory, differential geometry, Hodge theory, algebraic geometry and mirror symmetry) from many internationally acknowledged mathematicians. In a second period, the project aims to reintegrate Dr Morando in the European scientific community letting him to develop his research in Europe. Moreover, the Università degli Studi di Padova will benefit of all the knowledge Dr Morando would have acquired in Japan. In particular, Dr Morando will be able to connect different research groups at the Università di Padova coming from algebra, geometry, analysis and physics. These groups seems to be heterogeneous and slightly related at a first sight but recent advances in mirror symmetry, algebraic geometry and differential equations have deepened the interconnections between them, linking very different problems and methods in mathematics and physics. Such recent techniques and results have been developed mainly in Japan and by mathematicians of the RIMS. Dr Morando is the perfect candidate for this project. He developed very good abilities in the processes of learning, teaching and cooperating in many different countries. He already established very good cooperations with Japanese or other foreign researchers which led to important scientific achievements. He will be able to pass the acquired knowledge to various research groups inside the Università di Padova even of different scientific nature. This project allows Dr Morando to highly increase his value inside the Università di Padova and the international scientific world in general as an expert in new interdisciplinary methods and areas at the forefront of the scientific research.

Keywords: algebraic geometry,differential equations,algebraic analysis,d-modules,riemann-hilbert correspondence,subanalytic sites
Macrophage Proteoglycans in Atherosclerosis (ATHEROGAG)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2011-07-01
End date: 2015-06-18
Duration (months): 28.0
Total project cost (EUR): 179390.4
EU funding (EUR): 179390.4
Participants: 1
Project status: CLOSED

Cardiovascular diseases (CVD) are the leading cause of death in Western societies. CVD-related deaths are primarily caused by complications of atherosclerosis, a disease initiated via focal infiltration and retention of lipoproteins in the subendothelial matrix of arteries due to a combination of aggregation and interaction with proteoglycans produced by the arteries. Little is known about the in vivo contribution of macrophage-derived and -associated proteoglycans during atherosclerosis development and progression. Considering this dearth of knowledge we will address two objectives: First, we want to determine the in vivo impact of reduced sulfation of macrophage proteoglycans on atherosclerosis using conditional mouse models lacking macrophage-specific Ndst1 functionality on an LDLR-deficient background. Atherosclerotic lesion quantity and quality will be analyzed in conjunction with macrophage lesion infiltration and lesion apoptosis and efferocytosis. Secondly, we want to evaluate the importance of proteoglycans for macrophage foam cell conversion, another key event in atherogenesis. Using macrophage cell cultures from wild-type or mutant mice we want to determine the importance of biosynthetic genes involved and the array of proteoglycans expressed before and after conversion. In addition the cells will be used to identify a specific proteoglycan important for conversion which will be consequently evaluated for its impact on atherosclerosis in vivo. During his mobility, the applicant will receive didactic (glycobiology, management, intellectual property, grants) and hands-on (MS, macrophage cultures, qPCR, shRNA, flow assay) training as well as network opportunities which will be implemented in the European return institution. Altogether, the generated data should add to our understanding of macrophage proteoglycans and their importance for CVD and provide the opportunity for identifying drug targets and for transfer of US collaborations and know-how to the EU

Keywords: medical sciences,cardiovascular system,histology,laboratory animal science,genetically modified organisms,cell biology,functional biology,molecular biology,proteomics,tissue culture
Homotopy quantum symmetries, monoidal categories and formality (HQSMCF)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2012-01-01
End date: 2014-12-31
Duration (months): 36.0
Total project cost (EUR): 225233.6
EU funding (EUR): 225233.6
Participants: 1
Project status: CLOSED

This project will be hosted at the MIT (outgoing host) and at the University of Zurich (return host). Its main objectives are : (I) to develop a theory of homotopy quantum groups. This can be understood as the natural the- ory that should sit at the intersection of four important disciplines of mathematics and physics : monoidal categories, homotopy theory, quantum groups and higher categories. This fact gives a clear multidisciplinary aspect to the proposal. (II) to prove the formality of the homotopy Lie algebra governing simultaneous deformations of a Poisson manifold and its coisotropic submanifolds. This is the key step in solving the problem of quantization of symmetries from the point of view of deformation quantization, giving interdisciplinary applications. These two objectives organize themselves into subobjectives : I1 ) define homotopy braided monoidal categories (∞-braided ∞-monoidal category) I2 ) define homotopy quasi-triangular quasi-Hopf algebras (∞-triangular ∞-Hopf algebras) I3 ) define monodromy for higher connections I4 ) give examples of higher Drinfeld associators I5 ) define and give examples of homotopy quantum groups II1 ) construct the homotopy Lie algebra governing simultaneous deformations of a Poisson manifold and its coisotropic submanifolds II2 ) prove the formality of this homotopy Lie algebra. Interdisciplinary aspects come also from tools used which are borrowed from physics (higher holonomies, branes, quantization) or from new rewriting techniques in computer science and operads (Gröbner basis).

Keywords: mathematics
Microbial Electrochemical Cells with modified electrode based on ‘forest’ like carbon nanotube (CNTs) and CNT- conducting polymers nanocomposites (BEC-ME)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-11-01
End date: 2013-10-31
Duration (months): 24.0
Total project cost (EUR): 271636.8
EU funding (EUR): 271636.8
Participants: 1
Project status: CLOSED

Microbial electrochemical cells (MECs) show promises for energy recovery from waste and efficient wastewater treatment. MECs are bioelectrochemical reactors in which chemical energy stored in reduced substrates is converted directly into electrical energy (or hydrogen) through immobilized microbial catalysts, usually termed electroactive biofilms (EAB). Current MEC performances are not optimal and prevent their use in large-scale applications. Slow electron transfer at the microorganisms/electrode interface and low overall electroactivity of EABs are among the key scientific bottlenecks that need to be resolved in order to increase MEC output and enable their cost-effective implementation in wastewater treatment plants (WWTP). A possible solution is the development of biocompatible advanced materials for electrodes that will enable efficient “wiring” of EAB to the electrode. This project focus on development of such electrode materials and their implementation in established MECs. The candidate will use ‘forest’ like carbon nanotube (CNTs) and CNT- conducting polymers nanocomposites (CNT-NCs) to modify conventional electrodes for MECs. The new electrodes will have high surface and biocompatibility and support a fully active EAB, thereby increasing extracellular electron transfer and power (or hydrogen) output in MECs. The training facilities and expertise of the host organization will be used to fulfill the multidisciplinary training of researcher needs for development of an independent research career. Additional training budget management and technology transfer provided within this project will add to the core skills of the candidate and enable her to take forward Research and Technology Development programmes. Moreover, the results could be of enormous global environmental benefit by ensuring the optimization of MEC as well as economic benefit by reducing costs for existing wastewater treatment systems.

Keywords: microbial electrochemical cells,modified electrode,carbon naotube,conducting polymers,nanocomposites