Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Laser Interference Lithography based 4D-printing of Nanomaterials (L4DNANO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark,China,United Kingdom,Spain,Germany,United States,Australia,Japan,Brazil,Switzerland
Call: MSCA Staff Exchanges 2021 (HORIZON-MSCA-2021-SE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 630200.0
EU funding (EUR): 630200.0
Participants: 14
Project status: SIGNED

By tackling the limitations of the current 4D-printing of nanomaterials, this project seeks to initiate a new process paradigm, laser interference lithograph (LIL) based 4D-printing, for rapidly and accurately producing truly 3D structural and large volume 4D nanomaterials. It achieves this by combining the advantages of laser interference lithograph with the advanced intelligent inks, producing state-of-the-art capacity of 4D nanomaterials manufacturing. This new method has the potential to the mass-production of 4D nanomaterials and to the market intake of the nanomaterials. In our approach, LIL patterning is applied and the patterns are stitched to form truly 3D nanostructures and then the infiltration of intelligent inks is performed. The approach is based on some established principles and prior art gained within the consortium but is yet to be further explored.The project creates new knowledge on LIL and metalens for 3D patterning and nanometrology, bioactivity-toxicity of 4D Nanomaterials and micro-structures influence to battery performance/life. The research and innovation objectives are to integrate volumetric laser interference lithograph scanning and deep exposure for rapid, accurate, truly 3D structures fabrication, to develop optimal alignment between interference pattern units and across patterned layers based on the state-of-the-art nanometrology and characterisation for accurate formation of large volume 3D nanostructures, and to accomplish controlled infiltration for the formation the 4th dimension of nanomaterials. The new technique will be pioneered on biomedicine and engineering applications. The objectives are ambitious and require international level collaborations. The project addresses the collaborations by initiating a long-term collaboration platform among consortium members and beyond. It also emphasis staff development via various joint research and innovation and training activities, particularly, the carefully arranged secondments.

Keywords: 4d printing,4d nanomaterials,laser interference lithography
International Dimensions and Effects of Populism (IDEoPOP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Brazil,France,United Kingdom,Türkiye,Sweden,Italy,Poland,Czechia,Greece
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2024-10-01
End date: 2028-09-30
Duration (months): 48.0
Total project cost (EUR): 2379002.4
EU funding (EUR): 2379002.4
Participants: 13
Project status: SIGNED

The doctoral training network IDEoPOP (International Dimensions and Effects of Populism) aims to study how the phenomenon of populism is related to world politics. While the global rise of populist political parties, governments and movements all over the world, from Hungary to India, from Italy to Mexico, from Turkey to El Salvador, has led to a great interest in the domestic implications of populism, its international effects have remained understudied. But populism impacts the foreign policy of single countries as well as international politics more broadly understood, and it is indeed frequently mentioned as one of the main causes for the crisis of the so-called liberal world order. The Doctoral Network IDEoPOP will consolidate the study of the international dimensions of populism as a research programme, shaping a new generation of scholars and developing policy-relevant insights on how to address the consequences of populism internationally. The focus will be on the ideational, institutional, diplomatic, and communicative international dimensions of populism. These will be addressed in four distinct Work Packages. The proposed doctoral network is driven by the following overarching research question: How are domestic and international politics related in populism, and how does populism impact international politics? As the phenomenon of populism is likely to continue affecting citizens’ lives, state institutions, regional integration efforts, and the liberal international order in the years to come, a better understanding of its international implications is of utmost importance. Under the guidance of some of the leading scholars in this area, a new generation of doctoral researchers will be trained in the study of the international dimensions and effects of populism and will contribute to the Network’s efforts at jointly addressing the overarching research question.

Keywords: populism in international relations,manifestations and consequences of populism in ir,populist leaders,populist parties,populist communication strategies,diplomacy,international orders in populism
Advanced Database for Biomaterials with Data Analysis and Visualisation Tools extended by a Marketplace with Digital Advisors (BIOMATDB)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Coordination and support actions
Countries involved: Austria,Spain,Norway,Finland,Poland,Portugal,Italy,Ireland
Call: Biomaterials database for Health Applications (CSA) (HORIZON-CL4-2021-RESILIENCE-01, 2021)
Start date: 2022-06-01
End date: 2025-02-28
Duration (months): 33.0
Total project cost (EUR): 2799150.0
EU funding (EUR): 2799149.0
Participants: 12
Project status: CLOSED

Biomaterials in healthcare span almost all medical fields, ranging from recognised materials to high-innovative smart and multi-functional biomaterials. One of the main challenges is to provide accessible and well-structured data of biomaterials for all relevant practitioners and user groups. BIOMATDB aims to create an advanced database for biomaterials providing detailed information on its properties. Flexible data analysis and visualisation tools support the search and selection process based on analyses of the results of biological testing of biomaterials from the scientific literature to incorporate data on as many of the material properties as possible. BIOMATDB also provides a web-optimised information marketplace and digital advisors to support companies, especially SMEs, in offering their products and properly presenting themselves at global scale. Initiated by biomaterial use cases, the web application will match the suppliers and demanders through intelligent matching tools and step-by-step decision support. BIOMATDB focuses on the creation of a label of biocompatibility to define the suitability of a biomaterial for use in a medical device or advanced therapy and to assist companies, especially SMEs, in choosing and facilitating market access for their products providing them a better guidance. All created technical systems and data processing methods are tested within existing open innovation testbeds and validation groups. Intuitive training manuals and compact online video tutorials support the use of the database, marketplace and label. Appropriate business models are derived for securing the long-term sustainability of the created solutions. The project has a significant impact on the findability and searchability of existing biomaterials at the pan-European level. It is an enabler for better uptake of biomaterials in future health applications and medical therapies.

Keywords: biomaterials,database,data analysis,digital advisors,marketplace,innovation testbeds
Resolving Surface Reactions in Plasma Catalysis: Towards Rational Catalyst Design (SURPLAS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Renewable energy is key to tackling climate change and reducing our dependence on fossil fuels. The intermittent supply of renewable energy hampers its efficient usage and creates a pressing need for innovative energy conversion approaches. Energy-to-fuel conversion using plasma-assisted catalytic conversion (PLAC) is highly promising for producing urgently needed fuels from greenhouse gases. In PLAC, reactants are activated in a plasma discharge, allowing for remarkable efficiencies beyond the limits of thermal catalysis. The catalyst surface defines the reaction pathway and selectivity, and is thus key in catalyst design. However, at present the active state of catalyst surfaces in plasma is unknown, limiting the impact of PLAC by inhibiting the design of dedicated plasma catalysts. In SURPLAS, I will overcome this challenge and unlock the full potential of PLAC by determining the surface reaction mechanisms of catalysts in plasma and demonstrating the rational design of plasma catalysts for CO2 hydrogenation. My expertise in surface reactions, materials design, and in situ spectroscopy forms the basis of a pioneering approach to analyzing surfaces while they are exposed to microwave plasma. My group’s unique embedding with plasma experts from industry and academia will facilitate the study of complex catalyst-plasma interactions. I will be the first to determine the active state of single-crystal surfaces and applied powder catalysts in plasma and to derive trends in selectivity and metal-support interactions in PLAC. This breakthrough in understanding will allow for the rational design of plasma catalysts, which I will validate by catalytic performance measurements. This project will revolutionize PLAC by demonstrating catalyst design based on atomic-scale understanding of surface reactions in plasma. SURPLAS will allow me to lead the way into a new era of energy conversion, at a time when urgent need for fuels meets record growth in renewable energy.

Keywords: surface chemistry plasma chemistry
Digital Autonomy for RISC-V in Europe (DARE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: European High Performance Computing
Action type: Framework Partnership Agreement
Partnership: EUROHPC (JU-JTI)
Countries involved: Spain,France,Italy,Finland,Germany,Belgium,Sweden,Greece,Croatia,Portugal,Austria,Czechia,Poland,United Kingdom,Netherlands
Call: Framework Partnership Agreement (FPA) for developing a large-scale European initiative for High Performance Computing (HPC) ecosystem based on RISC-V (HORIZON-EUROHPC-JU-2022-TECH-03, 2022)
Start date: 2024-10-01
End date: 2030-09-30
Duration (months): 72.0
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 51
Project status: SIGNED

The HPC Digital Autonomy with RISC-V in Europe (DARE) will invigorate the continent’s High Performance Computing ecosystem by bringing together the technology producers and consumers, developing a RISC-V ecosystem that supports the current and future computing needs, while at the same time enabling European Digital Autonomy. DARE takes a customer-first approach (HPC Centres & Industry) to guide the full stack research and development. DARE leverages a co-design software/hardware approach based on critical HPC applications identified by partners from research, academia, and industry to forge the resulting computing solutions. These computing solutions range from general purpose processors to several accelerators, all utilizing the RISC-V ecosystem and emerging chiplet ecosystem to reduce costs and enable scale. The DARE program defines the full lifecycle from requirements to deployment, with the computing solutions validated by hosting entities, providing the path for European technology from prototype to production systems. The six year time horizon is split into two phases, enabling a DARE plan of action and set of roadmaps to provide the essential ingredients to develop and procure EU Supercomputers in the third phase. DARE defines SMART KPIs for the hardware and software developments in each phase, which act as gateways to unlock the next phase of development. The DARE HPC roadmaps (a living document) are used by the DARE Collaboration Council to maximize exploitation and spillover across all European RISC-V projects. DARE addresses the European HPC market failure by including partners with different levels of HPC maturity with the goal of growing a vibrant European HPC supply chain. DARE Consortium partners have been selected based on the ability to contribute to the DARE value chain, from HPC Users, helping to define all the requirements, to all parts of the hardware development, software development, system integration and subsequent commercialization.

Keywords: tapeout,chiplet,supercomputing centres,eu soverignity
Drivers and Brakes of CAR T Cell Efficacy Determined by the Tumor Immune Microenvironment (CAR-TIME)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1499875.0
EU funding (EUR): 1499875.0
Participants: 1
Project status: SIGNED

Cancer immunotherapies with chimeric antigen receptor (CAR) T cells have shown dramatic clinical efficacy in patients with B cell neoplasms. Thus, their clinical use is expected to increase considerably in the near future. However, for poorly understood reasons, not all patients with lymphoma benefit from these expensive therapies. The ability to stratify patients into probable responders vs. non-responders prior to immunotherapy will improve treatment efficacy, limit patient exposure to adverse effects, and mitigate the significant economic costs associated with these therapies. We and others have previously demonstrated that effective antitumoral immunity requires complex, spatially coordinated interactions between different cellular elements within the tumor immune microenvironment (TIME). There is evidence that patient response to immunotherapy is attributed to specific characteristics of the TIME, such as the composition, spatial arrangement, and activation states of immune cell types in it. Therefore, a better understanding of the TIME, and of how immunotherapies come into effect in live, intact human tissues, is critical for the selection of successful immunotherapies for our patients. The overarching aim of the CAR-TIME project is to explore and visualize the cellular and molecular mechanisms of CAR T cell efficacy in lymphoma, determined by CAR T cell interactions with the TIME. This shall be achieved by creating a high-dimensional map of the TIME of diffuse large B cell lymphoma, performing live tissue cultures treated with immunotherapies, and establishing a novel live cell microscopy platform to interrogate intact human lymphoma tissue treated with CAR T cells. Drug perturbations, multidimensional imaging technologies, RNA sequencing and integrative bioinformatics analysis will illuminate mechanisms of therapy response vs. resistance, reveal novel predictive biomarkers, and inform future combination immunotherapy strategies to improve patient outcomes.

Keywords: highly multiplexed microscopy,light sheet microscopy,live cell microscopy,lymphoma,car t cells,combination immunotherapy
Hydrological changes and chemical weathering through time in the southwestern Alps using isotopes from siliceous microalgae (Hydro-ALPS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-07-01
End date: 2024-06-30
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: CLOSED

Across middle Europe, the Alps cover four sub-climatic regions and play a major role in accumulating and supplying water to the continent. Famously called as the “water towers of Europe”, they host most of the headwaters of the rivers Danube, Rhine, Po and Rhone. Located in the Mediterranean basin, the southwestern Alps are known to be particularly vulnerable to flood, landslide events and summer droughts. Precipitation is expected to decrease by 20-30 % in the Mediterranean basin by 2100 threatening water resources. However, large uncertainties remain on future precipitation regimes at a local scale. Climate models spatial resolution do not integrate regional climate heterogeneity and models are calibrated on a short temporal “observations” window (the last century mainly). The Hydro-Alps project aims at providing new perspectives on the history of past local hydrological changes that needs to be considered in order to improve climate projections and strategies to water resources issues. Hydrological changes and chemical weathering will be studied in the southwestern Alps for the pre-industrial period and over several millennia. Valuable information can be provided by microalgae called diatoms which are accumulating through time in the sediments of alpine lakes. They build a cell wall in silica (SiO2) which records lake water chemistry during the shell formation. The project will rely on measurements of oxygen and silicon isotopes from diatoms extracted from lacustrine sediments used as tracers of local hydrological conditions and chemical weathering of the crystalline bedrock. This innovative approach will provide new information on mountainous past climate variability by combining isotopic tracers on same sample and new perspective about long-term changes in the Mediterranean climate. Altogether, the Hydro-Alps project will improve our understanding of climate changes at local scale and will help stakeholders to adapt water resource strategies.

Keywords: lake sediments,diatoms,hydrological changes,chemical weathering,oxygen isotopes,silicon isotopes,southern alps,mediterranean basin
Resilience enhancement of fire-protected steel frames under multi-hazards (MulHazardRes)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Greece
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 169326.72
EU funding (EUR): 169326.72
Participants: 1
Project status: SIGNED

The prosperity and sustained economic growth of societies depend on the safe and continuous operation of infrastructures, which can be challenged by the impact of catastrophic hazards (e.g., earthquakes, fire, tsunami, etc.). The best solution is to ensure infrastructures have adequate resilience against potential multi-hazards on a scientific knowledge base. The proposed MulHazardRes project will develop a performance-based methodology for evaluating and improving the resilience of fire-protected steel building structures against earthquake hazards and post-earthquake fire hazards that is raising major international scientific and industrial interest. This methodology will be sophisticated and practical. First, collaborative research efforts will be made to assess the vulnerability of fire-protected steel building structures under various earthquake and post-earthquake fire scenarios through both experimental and numerical investigations. Second, resilience enhancement technologies will be developed by reducing the damage of spray-applied fire-resistive materials, plastic damage of steel components, structural residual deformations, and combined damage of steel materials because of strong earthquakes and post-earthquake fires. Finally, design criteria, design methods, and life-cycle risk-based estimation approach will be developed within the performance-based methodology to enhance the resilience of fire-protected steel frames against earthquake and post-earthquake fire hazards. The research outcomes of the proposed MulHazardRes project hold the potential to significantly advance the state of the art in better safeguarding the infrastructure systems against multi-hazards.

Keywords: resilience,multi hazards,earthquake,post earthquake fire,fire protected steel structures,performance based engineering,structural engineering,life cycle risk based estimation