Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Development of environmentally-friendly Bio-sources aerogel as the support Core for vacuum insulation panels (VIPs) (BioCore VIP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

This Marie Sklodowska Curie Individual Fellowship will bring an outstanding experienced researcher to work in Europe and be mentored by a world leading expert in low energy building technologies. Over the past 20 years, the Incoming Research Fellow, Prof Fatang Jiang has specialised in biodegradable materials and been an active technology entrepreneur by successfully commercialising his research outcomes including polysaccharide sponges and aerogels, edible desiccants, biodegradable and structure controllable superabsorbents for water retention, and innovative water activity measurement. The proposed project has been carefully chosen to match the researcher's experience in bio-sources materials with the host scientists’ expertise in low energy building technologies to produce some innovative outcomes and create new benefits to the society in Europe. The project aims to develop an environmentally-friendly bio-sources aerogel as the support core for vacuum insulation panels (BioCore VIP). Thermal insulation is a primary approach to reduce the buildings’ energy demand. Aerogel, particularly encapsulated in vacuum panel with a multilayer film, is a super insulation material with an extremely low thermal conductivity and hence can obtain the required thermal resistance with a very small thickness, which is desirable commercially in order to minimise the effect of insulation on the building usable space. Development of the proposed aerogel requires comprehensive scientific knowledge including material preparation, freeze-drying, heat transfer and buildings’ energy analysis. Combination of the expertise between the Incoming Researcher and the host team matches this requirement perfectly. In addition to the scientific goals, the Incoming Researcher will contribute his expertise on polysaccharide aerogel and soil water retention to provide training for researchers, students and industrial contacts by hosting seminars, giving lectures and participating in outreach activities.

Keywords: polysaccharide aerogel,biodegradable,hydrophobic modification,structure controllable,thermal insulation,vacuum insulation panel vip
ANTOFERINE: An innovative eco-friendly process for chemical solvent free extraction of bioactive antifungal polyphenols from vineyard waste. (ANTOFERINE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-05-01
End date: 2018-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The agro-food sector is facing today crucial challenges. With a global population expected to reach 9 billion by 2050, meeting the global demand for food supply would not only require increasing production, but also to prevent food losses. Close to 50% of the global fresh produce, mostly fruits & vegetables, is lost in the post-harvest stage due to spoilage during transport and storage, with 80% caused by fungal contamination. Besides damaging product quality, fungal growth poses a risk to consumers due to secretion of mycotoxins, carcinogenic and immunogenic metabolites from fungi. The cumulative cost of post-harvest losses exceeds €200 billion annually. To prevent these losses, post-harvested produce has been traditionally protected with chemical-based solutions. However, besides the direct risk for applicators, these products also leave residues that are hazardous for consumers and the environment. Trying to find a balance between the prevention of losses and reducing risk for consumers, the EC has set residue allowance limits for synthetic compounds and seeks to replace them with natural alternatives. In response, we at Antofénol present an innovative antifungal solution of natural origin to protect fruits & vegetables in the post-harvest stage. The efficacy of our product relies on its unique composition of polyphenol extracts, obtained through a solvent-free extraction process that isolates them from vineyard waste. Importantly, besides contributing to reduce the huge post-harvest losses that affect the food sector, we would be contributing to the European circular economy by promoting valorization of an abundant agricultural waste. Altogether, the main goal of this project is to finalise the development of our biocontrol product and take our extraction process to the industrial scale. To meet these goals, in Phase 1 we see necessary to conduct a Feasibility Study that help us define the best strategy to overtake key milestones and lead us to market readiness.

Keywords: food security,antifungal,post harvest,biocontrol products,polyphenols,vineyard waste valorization,fungal contamination
Isotopic links to atmopheric water's sources (ISLAS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Norway
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-08-01
End date: 2025-01-31
Duration (months): 78.0
Total project cost (EUR): 1999054.0
EU funding (EUR): 1999054.0
Participants: 1
Project status: SIGNED

The hydrological cycle, with its feedbacks related to water vapour and clouds, is the largest source of uncertainty in weather prediction and climate models. Particularly processes that occur on scales smaller than the model grid lead to errors, which can compensate one another, making them difficult to detect and correct for. Undetectable compensating errors critically limit the understanding of hydrological extremes, the response of the water cycle to a changing climate, and the interpretation of paleoclimate records. Stable water isotopes have a unique potential to serve as the needed constraints, as they provide measures of moisture origin and of the phase change history. We have recently spearheaded a revised view of the atmospheric water cycle, which highlights the importance of connections on a regional scale. This implies that in some areas, all relevant processes can be studied on a regional scale. The Nordic Seas are an ideal case of such a natural laboratory, with distinct evaporation events, shallow transport processes, and swift precipitation formation. Together with recent technological advances in isotope measurements and in-situ sample collection, this will allow us to acquire a new kind of observational data set that will follow the history of water vapour from source to sink. The high-resolution, high-precision isotope data will provide a combined view of established and novel natural isotopic source tracers and set new benchmarks for climate models. A unique palette of sophisticated model tools will allow us to decipher, synthesize and exploit these observations, and to identify compensating errors between water cycle processes in models. In ISLAS, my team and I will thus make unprecedented use of stable isotopes to provide the sought-after constraints for an improved understanding of the hydrological cycle in nature and in climate models, leading towards improved predictions of future climate.

Keywords: atmospheric water cycle
Digital Humanities Laboratory: Studying the Entanglement of Infrastructure and Technology in Knowledge Production. (DHLab)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2023-09-01
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

The rise of digital humanities labs has provoked new research questions, yet not present in the humanities, about knowledge production intertwined with technologies and the infrastructural influences on humanistic work. To this end, I propose to conduct a novel ethnographic study of digital humanists at work, combined with a critical analysis of local infrastructure. The research has three main objectives: 1) the epistemological goal is to develop a new theoretical framework for examining a laboratory in Digital Humanities (DH) drawing on Science and Technology Studies and Knowledge Infrastructures; 2) the methodological task aims at integrating laboratory ethnography and the ethnography of infrastructure to build a new toolset for studying the intertwining of human organisation and infrastructure; and 3) the central work package focuses on investigating DH knowledge creation based on two case studies: King’s Digital Lab and the Cambridge Digital Humanities Lab. The case studies will provide comprehensive and comparative knowledge of DH organisational systems and practices. The study will be based on the observation of, and interviews with, participants involved in the labs, the analysis of written documents, and the analysis of digital communications. This project comes at a key moment, one at which, it is necessary to examine the impact of socio-material assemblages on the process of knowledge production in order to improve the research infrastructure. I shall expand the emerging area of Critical Infrastructure Studies through contributions to the body of theoretical work and the formation of a Critical Infrastructure Reading Group at King’s College London. This project will establish me as a leader in the critical studies of space and organisational structures associated with humanistic research. In addition, I will receive training in the applied DH and ethnographic methods, which will give me new competencies and enhance my ‘digital humanist’ profile.

Keywords: digital humanities,infrastructure,laboratory,knowledge production,technology,science and technology studies,social practices,collaboration,laboratory ethnography,ethnography of infrastructure
The Physics of Metal Plasticity (PMP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Denmark
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2020-10-01
End date: 2025-09-30
Duration (months): 60.0
Total project cost (EUR): 2496793.0
EU funding (EUR): 2496793.0
Participants: 1
Project status: SIGNED

The societal need to conserve materials and energy calls for lighter and stronger metal components. The advantage of metals is their unique combination of plasticity (i.e. formability) and strength, which is governed by their complex structure. This structure is organized hierarchically on several length scales. In contrast to functional materials and polymers, this complexity has led to the common theoretical framework being not physics, but an engineering science: metallurgy. As a result, phenomenological models prevail. The big obstacle to understand the underlying physics is the lack of visualization of the dynamics of the structure. From 2012 to 2019 I have developed a hard x-ray microscope for high-resolution 3D studies. Uniquely, this now allows us to zoom into the material and map grains and dislocations. This will enable 3D movies on all relevant length scales. No competing group will have anything similar within the next 5 years. PMP will exploit this to unravel the physics of plasticity. For the first time, we can directly see the processes involved: the creation of dislocations, their self-organization, and subsequent creation of ever more complex patterns. At the same time, we can deduce the local stress. This will provide answers to longstanding core questions of metal science. Current multiscale models of plasticity are not capable of predicting realistic patterns. The new data will guide theory and allow for direct comparison of models and experiment at all scales. PMP will develop a physics-based multiscale model of plasticity that for the first time can predict which patterns evolve when and where in the metal, and as a result greatly improve predictions of the macroscopic plasticity and strength. If successful, we have created the instrumental and modelling foundation for a new paradigm in structural materials. This will support the ultimate vision of materials and process design in computer models rather than trial and error in the lab.

Keywords: synchrotron based x ray imaging,dislocations in metals
Metalloradical Catalysis - From Fundamental Studies to Applications (MetalloRadiCat)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-05-01
End date: 2025-10-31
Duration (months): 66.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Over the past decades, metal catalysis has had a tremendous impact in chemistry, its adjacent disciplines and society overall, having gained an omnipresence in academic and industrial research worldwide. Numerous previously unthinkable transformations can nowadays be achieved in a selective and relatively mild manner owing to the metals' unique ability to trigger bond-making and breaking via pathways and principles that are inaccessible to metal-free processes. In this context, the global community has focused primarily on closed-shell, two electron processes for synthetic transformations. By comparison, the field of metalloradical catalysis has seen much less development, although metalloradicals are nature's preferred species to tame radical reactivities under non-precious metal-catalysis in numerous metalloenzymes. This is likely due to our currently limited understanding of metalloradical reactivity and its associated principles, and as such also limited ability to rationally design metalloradical catalysts and catalytic processes. A multidisciplinary approach, which capitalizes on the principles and insights of organic, organometallic and biological processes, will likely be key to meet the next frontier in this promising field. The objective of this proposal is to combine the tools of mechanistic, computational and synthetic organic/organometallic chemistry to explore catalysis with metalloradicals in synthesis, materials research and enzymatic processes. The proposed program will investigate some of the most pertinent questions in relation to the emerging area of remote functionalizations for the selective synthetic access to tailored molecules, olefin migrations and manipulations, and naturally occurring (enzymatic) metalloradical-catalyzed processes in the context of methane production and activation.

Keywords: catalysis,mechanistic studies,organometallic,reactivity design,computation,synthesis,radical
A rapid non-invasive on-chip miRNA-based Sputum Assay for early stage Lung Cancer Screening (MI-SCAN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-01-01
End date: 2023-06-26
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: SIGNED

Lung cancer is one of the leading causes of cancer mortality in the world accounting for an estimated 1.8 million deaths, 18.4% of the total in 2018. Approximately 85% of lung cancers are classified as non-small cell lung cancer (NSCLC), a less aggressive form of tumor than small cell lung cancer (the remaining 15% of all lung cancers). The gold standard diagnostic methods for lung cancer patients include X-ray, low-dose CT and sputum cytology which are not efficient for early stage diagnosis of lung cancer. Lately, analysis of molecular markers has been proposed as a useful tool for cancer diagnosis in early stage. Molecular analysis of sputum is reported for identifying the cells bearing tumor-related genetic aberrations; therefore, it is specific and sensitive than cytological analysis. Furthermore, using non-invasive sputum sample have potential application for screening by molecular methods for regular health checking clinics. The proposed interdisciplinary methodology is to combine the Micro-RNA (miRNA) bioassay on microfluidic chip with Surface Enhanced Raman Scattering (SERS) spectroscopy. The goal of the project is to develop non-invasive detection of early stage (I, II) lung cancer using miRNA biomarker on-chip with multiplexed SERS technology. The overall system integrates a microfluidic device with gold particle linked with RNA probes that can capture target miRNA biomarkers for lung cancer cells. The SERS is used to generate a signal peaks when a positive test result occurs. Importantly, this biosensor platform will have several advantages over existing techniques. i) It is a label-free, amplification-free method for rapid miRNA detection. ii) The sensor platform can monitor multiple targets simultaneously. The project will eventually develop a portable and novel integrated platform by incorporating commercially available custom made portable Raman detectors for sensitive and selective detection of lung cancer at very early stage.

Keywords: mirna diagnostics,sers detection,microfluidic chip,poc system
Democracy without Majorities: Political Representation under Minority Rule (MINORITYRULE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Minority rule is a frequent phenomenon in many parliamentary democracies. In minority governments, political parties in cabinet neither enjoy majority support in the electorate nor in parliament. Minority rule has become more prevalent in a time when party systems in democracies are experiencing drastic changes. Citizens’ voting behavior has become more volatile, new challenger parties – including populist radical right parties – have permanently entered the political landscape, and parliaments have become more fractionalized. The implications of the increasing phenomenon of minority rule for the functioning of democracy and political representation are possibly far-reaching. Unfortunately, existing theoretical and empirical approaches are insufficient to understand the consequences of minority rule for party systems, governmental behavior, and citizens’ responses. MINORITYRULE’s objective is therefore to provide a broad and systematic comparative analysis of the implications of minority rule for political representation. The project investigates how minority rule affects the intensity of political polarization between political parties during parliamentary debates and election campaigns, how it constrains the responsiveness of governments to public opinion at the national and European level, and how citizens evaluate the legitimacy of minority rule. MINORITYRULE will accomplish these tasks on the basis of an unprecedented comparative data collection using novel multilingual text-as-data approaches and cross-national survey experiments. Ultimately, the project will lead to a new theory of political representation under minority rule. In light of changing party systems, MINORITYRULE will generate new insights about the nature of political representation in which governments rule without stable majorities in parliament and society.

Keywords: political representation,minority governments,responsiveness,public opinion,text as data,survey experiments
White Light Emitting Lanthanide Metal Complexes for Electroluminescent Materials (WHITELIGHT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-01-02
End date: 2020-07-01
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

There is an urgent need to develop a new generation of more efficient and durable illumination sources to surpass the limitations of the conventional lighting systems. Solid State Lighting sources based on Light Emitting Diodes (LEDs) or Organic LEDs (OLEDs) devices are emerging as the next generation systems for general illumination. White LEDs on the market outperform the traditional incandescent and fluorescent lamps, both in term of efficiency and lifetime. More work has still to be done to develop their organic counterpart, OLEDs. These offer the distinctive possibility to fabricate large area flat and also flexible devices by vacuum or solution processing, i.e. by potentially less expensive and less energy-consuming production protocols. For this, the development of electroluminescent materials that show high brightness, easy synthesis, good chemical and electrical stability, low cost, and simple processing is actively pursued. In this context, WHITELIGHT targets the development of single-molecule white light emitting materials for the fabrication of OLEDs, containing Eu(III) (red), Tb(III) (green) lanthanide ions and bis(2-pyridyl)amine based ligands (blue) emitters. This is a very ambitious and multidisciplinary goal that requires a range of expertise spanning from theoretical chemistry to physical device fabrication and testing. The research unit at the hosting institution has a strong background in the photophysics of materials for light/ energy conversion, complemented by an expertise in the design and synthesis of organic luminescent materials, as well as the fabrication and testing of electroluminescent devices. On the other hand, the Experienced Researcher has a strong background in the synthesis of luminescent lanthanide complexes. This unique combination of expertise is a major factor for the successful implementation of the proposed research.

Keywords: lanthanide metal complexes,luminescence,energy transfer,luminescent materials,white light,electroluminescent devices,oled