Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Lower THz rAdio propagation channeL sounding, parameter Estimation and modeliNg Towards 6G and beyond (TALENT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Sweden,Denmark
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-07-01
End date: 2024-06-30
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 2
Project status: CLOSED

The new lower THz band from 100 GHz to 1 THz is considered as a candidate for 6G and beyond systems towards 2030 that require even larger system bandwidths. As wireless systems must be designed with constraints set by the radio propagation channels, understanding the lower THz channel characteristics is essential for realistic system design and performance analysis of communication, positioning and sensing operating at this band. However, they are almost remaining unknown with a few works reported, due to challenges in channel sounder development, low-cost high-resolution parameter estimation (HRPE) and establishing comprehensive and realistic 6G-compatible channel models. The applicant will address these challenges with Professor Fredrik Tufvesson, a world-leading researcher in channel measurements and characterization, at the host Lund University. The applicant, collaborating with experts in the host and secondment groups, will introduce basic theory and technology breakthroughs to explore the new lower THz band, which include 1) a novel real-time channel sounder, 2) a generic HRPE algorithm and 3) spatially consistent channel models. The project will result in at least four peer-reviewed journal papers, four conference papers and related presentations, and other broader dissemination, communication and exploitation activities. Undertaking the formal research and training activities, the applicant will achieve an excellent scientific profile in radio propagation, experienced skills in teaching, supervision, fundraising and management, and enhanced research network. This enables him to develop into an independent and leading researcher and realize his career plan within academia. The project also contributes to Europe’s Digital Decade, a vision and avenues presented by the Commission in March 2021 for Europe’s digital transformation by 2030, by facilitating an efficient, low-cost, credible, better and timely development of 6G and beyond wireless systems.

Keywords: radio propagation,dynamic channel characterization,sub thz,140 ghz,spatial consistency,channel sounding,high resolution parameter estimation hrpe,clustering,channel modeling,6g
Immunomodulatory properties of L. plantarum extracellular vesicles in airway allergy (LactoVES)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Austria,Czechia
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-07-01
End date: 2024-07-31
Duration (months): 25.0
Total project cost (EUR): 199440.96
EU funding (EUR): 199440.96
Participants: 2
Project status: CLOSED

The aim of the project is to conduct basic scientific research on the immunomodulatory properties of Lactobacillus plantarum (L. plantarum) extracellular vesicles in terms of their applicability in the treatment/prevention of airway allergies. The project assumes a comprehensive characterization of vesicles, starting from the description of their physicochemical properties, through in vitro tests using respiratory epithelial cell lines, to in vivo tests on mouse models of airway allergy. The project combines two areas, both the physicochemical characteristics of nanoparticles such as extracellular vesicles and advanced immunological research.

Keywords: vesicles,allergy,birch pollen
Doing it for kicks? Parsing the contributions of arousal perception and appraisal as drivers of excessive gambling (GamblingEmotion)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Canada
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 280751.52
EU funding (EUR): 280751.52
Participants: 2
Project status: SIGNED

Psychological theories of emotion and cognition agree that emotional experiences play an important role in decision making and risk evaluation. For emotions to influence decision-making, individuals need to perceive these emotional signals (i.e. interoception), and appraise them appropriately (e.g. attribute as an internal state). These processing stages have been found to be abnormal in some forms of mental illness. In gambling behaviour, it is assumed that abnormal levels of arousal are a source of reinforcement and can lead to problematic gambling participation. Yet, the underlying mechanisms remain unclear, and emotional signals alone (e.g. heart rate changes) do not reliably differentiate people with and without gambling problems. The current project will clarify the role of arousal in disordered gambling to close this knowledge gap by using a novel approach to separate the contributions of arousal perception, and the influence of risk and ambiguity on arousal and the appraisal of arousal. Work package (WP) 1 will record psychophysiological measures of arousal in people who gamble, and assess their relationships with the subjective perception of arousal. WP 2 will examine the influence of risk and ambiguity on the ability of arousal to predict decision making. WP 3, will investigate whether unrelated (‘incidental’) arousal is attributed to the gambling episode and influences decision making in gambling behaviour. Combining computational modeling and psychophysiological measurements is a new experimental approach which will give additional insights in identifying which of these emotional dimensions are perturbed in gambling. The proposed research will have implications for gambling policy, and targeting emotional components in prevention and treatment of gambling addiction.

Keywords: emotion,gambling,decision making,computational modeling,arousal
Impact of BRCA2 deficiency one the DNA damage response and Immunogenicity of Prostate cancer after Radioligand therapy (BRCA-RLT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-03-01
End date: 2026-02-28
Duration (months): 24.0
Total project cost (EUR): 187624.32
EU funding (EUR): 187624.32
Participants: 1
Project status: SIGNED

Despite current advances in prostate cancer (PCa) treatment, 10 to 20% of PCa will evolve to a metastatic stage, where the overall survival is 14 months. Radioligand therapy (RLT) is a new, promising treatment consisting in the injection of a radiolabelled vector. In PCa, this therapy targets Prostate Specific Membrane Antigen, which is overexpressed on PCa cells compared to other tissues. RLT has been shown to increase the overall survival of patients in clinical trials, but in order to improve its efficiency and identify possible biomarkers for patient selection, tumour response mechanisms must be studied. Especially, some reports indicate that deficiency in DNA Damage Response (DDR) genes could be correlated to an increased sensitivity of tumour cells towards RLT. In PCa, one of the most frequent deficient DDR gene is Breast cancer 2 (BRCA2), which is correlated with bad prognosis. In addition, retrospective studies showed a potential link between BRCA2 deficiency and a modulation of the immune response, which also influences treatment response. Therefore BRCA2 deficiency could impact both the immune response and RLT outcome. In this project, I will investigate the impact of BRCA2deficiency on RLT response. Both the tumour DDR and immunogenicity will be assessed, in order to view the treatment response as a whole. These studies will be conducted in vitro in murine and human PCa cell lines and in in vivo murine model. Results of my project will show the impact of BRCA2 deficiency on RLT outcome and whether BRCA2 status could be used as a biomarker to predetermine potential good responders to RLT. Besides contributing to the fundamental scientific advancement on the effect of BRCA2 deficiency in RLT response, I also aim to raising the awareness of these principles in the scientific community and other stakeholders such as clinicians. This will open the way to development of potential biomarker of good response to this new treatment

Keywords: radioligand therapy,dna damage repair,immune response,prostate cancer
Machine Learning Macroeconometric Methods for Dynamic Causal Inference (MACROML)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Denmark,Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-04-01
End date: 2025-03-31
Duration (months): 24.0
Total project cost (EUR): 230774.4
EU funding (EUR): 230774.4
Participants: 2
Project status: CLOSED

Data lies at the heart of all economic decisions. Everyone — and especially central bankers, investors, and policymakers — processes data when making choices. Thanks to technological innovations, the speed at which (raw) data are generated and shared by businesses, public administrations, and scientific research (among others) have increased exponentially. Large amounts of data bring new opportunities and challenges to econometrics. The literature on microeconometric methods based on statistical learning techniques has grown substantially over the last decade, yet macroeconometrics literature lacks an understanding of such methods which could be applied to answer causal inference questions. The primary goal of the macroml research project is to put forward theory-driven methods for dynamic causal inference analysis based on models typically used in the macroeconometrics literature, bridging the gap between machine learning and macroeconometric modelling. The key distinction of this project from the state-of-the-art methods is the analysis of heavy-tailed and highly persistent time series data — a critical feature that has been largely overlooked in the literature. In particular, the research project will investigate: I. accurate and theoretically-valid estimation and inference econometric techniques for general high-dimensional time series models; II. a general methodology for high-dimensional local projection estimators which allows studying the dynamic causal relationship between economic time series data. The project will enlarge policymakers’ toolbox for the analysis of macroeconomics and finance data to assess different dynamic causal hypotheses in a flexible and accurate way, thereby making it highly policy-relevant. In addition, new estimation methods of machine learning time series models will allow practitioners to implement ML techniques for time series data in a data-driven way. The project also will deliver several interesting empirical applications.

Keywords: machine learning,bootstrap methods,local projections,time series
Adolescent Autocracies: Pro-government student groups in resurgent authoritarian regimes (AAPSG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-01-01
End date: 2026-12-31
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 2
Project status: SIGNED

"Democracy in Retreat" was the 2019 title of the Freedomhouse index, which ascertained 13 consecutive years of a global decline in political rights and civil liberties from 2005 to 2018. The report foregrounds the alarming erosion of long-standing democracies and those part of "democracy's third wave", which began in the 1970s in Southern Europe, followed by countries in Latin America and East Asia and culminated in the dramatic regime breakdowns initiated by democratic reforms in Central-Eastern Europe (Soviet Union), South Asia, and sub-Saharan Africa. A period that has inspired scholars to deliberate the idea of democracy representing the "ultimate end of a country’s political development" or even the "end of history" itself. This period of democratization was initially lauded as a "linear set sequence", which would eventually encompass the globe. From the early 21st century on, however, a new generation of scholars has been describing a reverse wave of regime changes (Diamond, 2015; Lührmann & Lindberg, 2019). This "authoritarian resurgence" has evoked a scholarly debate on the causes, mechanisms, and perseverance of such "new" authoritarian regimes (Cassani & Tomini, 2019; Del Panta, 2019; Wiatr, 2019). While (university) student movements were commonly identified as prominent actors/forces of social change during the third democratization wave, my research will examine the role students play in the creation, maintenance, and innovation of (resurgent) authoritarian/autocratic regimes. They represent an alternative form of citizenship that neither fits needly into universalized social locations, such as "civil society", nor postcolonial conceptualization, such as Chatterjee's (2004) "political society". Using Bangladesh and Uganda as case studies, my research project explores how globally connected student groups are influential and understudied actors in autocratization processes and the shaping of these "new" regimes’ ideological foundations.

Keywords: student politics autocratization authoritarianism political violence social cohesion uganda bangladesh
Theorizing the Drivers of the Asylum-Far Right Nexus in Rural Europe (Mind-the-NEXUS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Italy
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 2333063.0
EU funding (EUR): 2333063.0
Participants: 2
Project status: SIGNED

Since 2015, mediatised episodes of protest and hostility towards refugees in rural areas in Europe have contributed to the perception of an alleged nexus between reception and the electoral success of far-right populist parties. However, despite the increasing interest of academic research, a patchy understanding of the factors and mechanisms driving the emergence of an asylum-far right nexus in rural areas persists. Whereas public opinion surveys emphasise the nationalistic orientation of rural Europe, research on policymaking has unravelled cases of welcoming and pragmatism. Mind-the-NEXUS will address this puzzle by leading the first systematic and comprehensive study of asylum politics in rural areas that in the last decade have been facing multiple challenges due to the arrival of different waves of refugees in times of reduction of public services (e.g., schools, hospitals etc.). It will do so by focusing on five European countries – France, Germany, Italy, Sweden and the UK – where municipalities represent key actors in reception policy. By adopting an innovative cross-country/cross-locality research design, Mind-the-Nexus will deliver a new understanding of the rural politics of asylum centred on the notion of Rural Political Arena (RPA), intended as the multilevel relational sphere where reception and integration policies take shape. Mind-the-NEXUS will deeply innovate scholarly and policy-oriented debates by expanding our understanding of opposition to refugees and FR politicization in still under-researched rural area. Through a mixed-methods approach combining Large-N quantitative studies on a newly compiled database, qualitative research on no less than 60 rigorously selected RPAs, and the first comparative rural elites survey, Mind-the-NEXUS will generate a ‘gold mine’ of data and break new ground in theorizing the meso-level institutional and political factors and mechanisms driving the emergence of an asylum-FR nexus in rural Europe.

Keywords: asylum,refugee reception,local government,local policymaking
The critical shift to single-cell formats in functional analyses of living cells (Cellularity)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 4926042.5
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The incredible potential of cell and immune therapy (CIT) is limited by technical challenges related to the standard analysis of immune cells in bulk, which neglects their heterogeneity. Single-cell functional resolution is essential to understand the full potential of immune cells. Current single-cell technologies are limited, low-throughput, high-cost and lack robustness, prohibitive for their implementation in CIT R&D, manufacturing and patient stratification. Samplix is developing Xplore, an all-in-one multiparameter single-cell analyser and sorter for screening, selection and expansion of immune cells based on functionality and potency. Xplore is a cost-effective solution that delivers higher throughput and sensitivity than current solutions, being compatible with CIT research workflows. Unlocking the full potential of CIT supports the faster and efficient development of new personalized therapies to treat serious diseases such as cancer, autoimmune diseases, and viral infections.

Keywords: cell therapy,microfluidics,cell line development,oncology,immunology,single cell assays,immune therapy,multicolor flow cytometry
Digital Technologies ActiNg as a Gatekeeper to information and data flOws (TANGO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: World-leading Data and Computing Technologies
Action type: Research and Innovation actions
Partnership: AI-DATA-ROBOTICS (co-programmed)
Countries involved: Spain,Belgium,Slovenia,Cyprus,France,Germany,Finland,Netherlands,Greece,Italy,Portugal,Luxembourg,United Kingdom,Sweden,Austria
Call: Technologies and solutions for compliance, privacy preservation, green and responsible data operations (AI, Data and Robotics Partnership) (RIA) (HORIZON-CL4-2021-DATA-01, 2021)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 10444121.01
EU funding (EUR): 10444121.0
Participants: 43
Project status: SIGNED

TANGO will establish a stronger cross-sector data sharing, in a citizen-centric, secure and trustworthy manner, by developing innovative solutions while addressing environmental degradation and climate change challenges. The overall outcome is a novel platform exhibiting the following capabilities: user-friendly, secure, trustworthy, compliant, fair, transparent, accountable and environmentally sustainable data management, having at its core technology components for distributed, privacy preserving and environmentally sustainable data collection, processing, analysis, sharing and storage. This platform will promote trustworthy and digitally enabled interactions across society, for people as well as for businesses. TANGO will leverage the power of emerging digital technologies to strengthen the privacy for citizens and private/public organisations, reduce costs and improve productivity. It will unlock the innovation potential of digital technologies for decentralised, privacy-preserving applications, while making accessible and demonstrating this potential within the GAIA-X and EOSC ecosystem. With 37 key partners from 13 countries, TANGO, is uniquely positioned to provide a high impact solution within the transport, e-commerce, finance, public administration, tourism and industrial domains supporting numerous beneficiaries across Europe. Through the provision of TANGO technologies, a trustworthy environment will be designed acting as a gatekeeper to information and data flows. Citizens and public/private organisations will be empowered to act and interact providing data both online and offline. TANGO will focus its activities on 3 main pillars: (i) the deployment of trustworthy, accountable and privacy-preserving data-sharing technologies and platforms; (ii) the creation of data governance models and frameworks; (iii) the improvement of data availability, quality and interoperability – both in domain-specific settings and across sectors.

Keywords: cross sector data sharing,secure and trustworthy,compliant,fair,transparent,accountable,environmentally sustainable data management,machine learning,artificial intelligence