Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The role of socio-economic status in experiences of displacement: The case of displaced Burundians in Kigali (SESED)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-04-01
End date: 2025-03-31
Duration (months): 36.0
Total project cost (EUR): 305778.24
EU funding (EUR): 305778.24
Participants: 1
Project status: SIGNED

In the last couple of years, with the surge of migrants crossing the Mediterranean Sea, migration, and forced migration has been gaining more attention. With a strong focus on desperate individuals, risking their lives on leaky boats, a stereotypical and limited picture is portrayed of migration in Africa and the Middle East. African forced migration has many different trajectories and in order to obtain a full comprehension of what conflict-related migration means and looks like the many different aspects of it need to be explored and understood, by academics and policymakers. Both urban residing and self-settled displaced people have received less attention by academics and policymakers alike. In addition, people of a high socio-economic position who forcibly move due to conflict in their home country, have received little to no attention. This research aims to fill this particular gap by exploring the lived experiences of Burundians of a high socioeconomic status who fled Burundi in 2015 and have been living in Kigali, Rwanda since. The overall objective is to explore what role socio-economic status plays in experiences of displacement, looking specifically at the decision to leave and choice of destination, integration into the host community, connection to the home country, and how gender interlinks to these experiences. The objectives will be reached using semi-structured interviews, supported by participant observation to ask forced migrants from Burundi about their experiences. The project is of importance for the Marie Sklodowska-Curie actions as it contributes to adding and deepening knowledge in relation to Sustainable Development Goal number 16 on peace, justice and strong institutions and to UNHCR’s Global Compact on Refugees. It also gives an opportunity to the researcher to restart her career in a EU country and through secondment to link institutes in an EU country and an AC that have not been linked before.

Keywords: burundians,rwanda,socioeconomic status,forced migration
High-ACCuracy printed electronics down to µm size, for Organic Large Area Electronics (OLAE) Thin Film Transistor (TFT) and Display Applications. (HI-ACCURACY)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Innovation actions
Countries involved: Germany,Austria,Germany,Italy,Belgium,Finland,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Materials, manufacturing processes and devices for organic and large area electronics (IA) (H2020-NMBP-TR-IND-2019, 2019)
Start date: 2020-04-01
End date: 2023-09-30
Duration (months): 42.0
Total project cost (EUR): 5907554.07
EU funding (EUR): 5220869.25
Participants: 12
Project status: SIGNED

HI-ACCURACY aims to deliver the next generation of large area manufacture of flexible OLAE structures such as organic Thin Film Transistors (OTFTs) and Electroluminescent Quantum Dot Light Emitting Diode (EL-QD-LED) displays, to µm-scale feature size printable onto flexible substrates. This is aimed at the large and exciting printed, flexible and organic electronics global market, estimated at €28.3bn with an annual growth rate of >8% which is mainly dominated by displays. Hi-Accuracy will display front- and back-plane structures with feature sizes approaching 1 µm using low cost materials that can operate at frequencies of >1MHz. This will be achieved through a unique range of cutting-edge materials and printing inks, in combination with inherently scalable, cost-effective printing and deposition approaches, that have non vacuum or minimal vacuum requirement. Specifically, the electronic materials will include a range of low-temperature curable nano-Ag and nano-Au conductors and p-type organic semiconductors with intrinsic mobility of 5-15sq.cm/V.s as well as InP, ZnSe and ZnS Quantum Dot (QD) materials and electroluminescent EL-QD-LED material stacks with multilayer barrier layers that can achieve the required WVTR and oxygen transmission rates. HI-ACCURACY is an ambitious project representing a pan-European EU consortium of world leading research centres and cutting-edge SMEs that are looking to develop and commercialise these technologies of European origin. The project is endorsed by three major global electronics companies: Huawei, Sony and Polar (global manufacturers of displays and wearable health monitors) who will sit on the External Expert Advisory Board and steer the project towards commercialisation. The final project demonstrators produced will be validated at the industrial facilities of one of the SME partners and the subsequent displays being further processed and tested by the end-user partners in their testing facilities (TRL5).

Keywords: electrostatic printing,electrostatic spraying,imprint lithography,p type organic semiconductors,nano ag,electroluminescent quantum dots,organic tfts,tft planes,amqled
Submesoscale Processes in a Changing Environment (SPICE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-08-01
End date: 2023-07-31
Duration (months): 24.0
Total project cost (EUR): 203852.16
EU funding (EUR): 203852.16
Participants: 1
Project status: SIGNED

I believe a key challenge to reducing the uncertainty of global climate model projections is quantifying the role of submesoscale (0.1-10km, hours-days) ocean processes on the ocean-atmosphere exchange of heat and carbon in the remote Southern Ocean. In SPICE, I aim to address this knowledge gap using ocean observations from state-of-the-art marine robots and high-resolution numerical models. Using this novel data I will for the first time 1) quantify the variability of heat and carbon air-sea fluxes in the Southern Ocean, and 2) better understand how upper ocean submesoscale processes modulate this exchange of heat and carbon between the atmosphere and the ocean interior, where it can be stored for millennia. SPICE will achieve three primary scientific objectives: (1) I will participate in an oceanographic research expedition to the Southern Ocean, to further learn about, and deploy autonomous ocean platforms. This pioneering science experiment will collect the required air-sea heat and carbon fluxes and oceanographic data in the sea-ice impacted Southern Ocean. (2) Perform scientific data analysis and research with my host, and during two secondments, to gain the longstanding skill and knowledge to quantify the impact of submesoscale processes on the air-sea flux of heat and carbon. (3) Employ a synergetic modelling and observational approach, whereby I will perform ultra-high-resolution simulations of the ocean to upscale the observational findings to address current and future climate challenges. By achieving these objectives, this Fellowship will provide me with the skills and network that I require to enhance my academic standing and research capability for years to come. This field of polar science is my passion and my longer-term ambition is to be an excellent and independent Earth System scientist who can build a long-standing career in Europe.

Keywords: ocean observations,numerical modelling,autonomous robotics
APC Postdoctoral EXcellence Programme (APEX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Fellowship programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Ireland
Call: Co-funding of regional, national and international programmes (H2020-MSCA-COFUND-2016, 2016)
Start date: 2017-09-01
End date: 2023-01-31
Duration (months): 65.0
Total project cost (EUR): 2832000.0
EU funding (EUR): 1416000.0
Participants: 1
Project status: CLOSED

APEX (APC Postdoctoral EXcellence) is an innovative intersectoral trans- disciplinary training, career development and mobility programme based at the APC Microbiome Institute, UCC, which focuses on the research area of gut microbiota and their role in human health and disease. APEX will offer 20 fellowships for incoming mobility with all fellows hosted in an APC academic host organisation: UCC, Teagasc, the Agriculture, Food and Development Authority (Teagasc) or the Cork Institute of Technology (CIT). Research at the APC aligns closely with Ireland’s Smart Specialisation Strategy, particularly in the strategic priority areas of diagnostics, food for health, and sustainable food production and processing, with significant potential for societal and economic impact in these areas. The aim of APEX is to develop the next generation of scientific leaders who will gain hands-on experience developing cross-disciplinary and entrepreneurial skills through individual research projects with a mandatory intersectoral (industry) secondment during their 2 year fellowship. Fellows can freely select the research theme, supervisor and host institution. APEX is designed to have maximum impact on the fellows, the host institutions and the hosts’ industry partners through training and innovative and translational research. While developing human capital, APEX will facilitate collaboration between academia and industry within and outside of the region, who will benefit from access to excellent researchers, key enabling research infrastructure and knowledge transfer. APEX will cultivate enterprise focused researchers to meet industry demands and support innovation along the Technology Readiness Levels (TRL) to bring societal and economic benefit to Ireland and Europe. Furthermore, APEX (via the fellows) aims to improve the perception of science, technology engineering and maths (STEM) as a career to school children as well as increase the level of awareness of its impact on society.

Keywords: trans disciplinary,career advancement,innovation,industry academia interface,intersectoral secondment,mobility,societal impact,strategic priority areas,transferable skills,knowledge transfer
Enzymatic DNA deamination and the immunity/cancer balance (APOBEC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-04-01
End date: 2017-03-31
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

Genomic instability is a key hallmark of cancer. Chromosome translocations require the formation of pairs of double-strand breaks (DSB) and trans-chromosomal ligation of the broken ends. Members of the AID/APOBEC family of enzymes deaminate cytosine (C) to uracil (U) in the context of a polynucleotide substrate. Excision of the U residue from DNA produces an abasic site, leading to incision of the DNA strand containing the abasic site by the conventional base-excision repair pathway. The introduction of proximal incisions on both DNA strands can generate a DSB intermediate for chromosomal translocation. AID acts on C residues at immunoglobulin loci in activated B cells to trigger antibody gene diversification and is the only member of the AID/APOBEC family that is currently known to act physiologically on endogenous nuclear DNA. Off-target deamination by AID results in nucleotide substitutions and genomic rearrangements in B lymphocyte tumours. APOBEC1 edits mRNA transcripts in the small intestine. Liver-directed misexpression of APOBEC1 is oncogenic in transgenic mice. APOBEC3 enzymes are ubiquitously expressed and act on C residues in the cDNA viral replication intermediates as part of a host restriction pathway. APOBEC3A and APOBEC3B have been shown to be capable of causing genomic damage in mammalian cells. Access to the nucleus by APOBEC family members likely permits DNA deamination activity that introduces mutations and genomic instability during tumourigenesis. I have generated mice that harbour FLAG-tagged forms of AID, APOBEC1, APOBEC3A or APOBEC3B inserted at the ROSA26 locus, preceded by a floxed stop sequence for conditional expression. This system will be used to understand the role of cytosine deamination in tumour progression in tissue- and time-specific contexts in vivo through whole genome sequencing of tumours. The long-term goal is to initiate the development of reagents to regulate APOBEC activity in basic science and clinical oncology.

Keywords: apobec,cancer,mouse model,b cell,hodgkin s lymphoma
Innovative, automatic, fast and cost-effective nanovesicles manufacturing equipment (NANOGO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-04-01
End date: 2019-09-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The global nanovesicles market size was valued at $1.18 billion in 2016 and is expected to witness an attractive CAGR of 7.2% until 2021. However, the current procedures for producing nanovesicles exhibit the following drawbacks: i) Do not allow for small volume (require at least 10 ml production), ii) Have low reproducibility, iii) Require various sub-processes and many man hours, leading to variable results based on who has carried out the procedure; iv) Are expensive (it is often necessary to create a small number of nanovesicles given that the compounds that they encapsulate are extremely expensive); and v) Are non-scalable (not only have problems with scaling up to large quantities, but also with producing small quantities). We at Nanovex Biotechnologies, increasingly disappointed with the current technologies for producing nanovesicles, have designed and prototyped NanoGo, a piece of microfluidics equipment that produces nanovesicles faster, better and at lower cost, for industrial applications. NanoGo is capable of producing small volumes (0.5 ml) to large volumes (4 liters/day) of nanovesicles. In addition, NanoGo has many other advantages: i) High reproducibility: The automation of the process allows you to obtain nanovesicles with reproducible characteristics (size, encapsulation efficiency, distribution). The result is the same regardless of who uses it and how many times you repeat the procedure; ii) Rapid process: Requires just 20 minutes to produce 50 ml of nanovesicles; iii) Ease of use: Anyone can do so with no knowledge of formulation; iv) Low cost. Requires a low volume of samples per experiment; v) Very easy to scale up. It is quite simple to increase the scale (1 to 100 chips -for instance- working in parallel).

Keywords: nanovesicles,nanobiotechnology,microfluidics,nanoencapsulation,drug delivery,nanomedicines
Model-guided Engineering of Complex Microbial Communities (ModEM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-10-01
End date: 2025-09-30
Duration (months): 60.0
Total project cost (EUR): 1995818.0
EU funding (EUR): 1995818.0
Participants: 1
Project status: SIGNED

Microbial communities occupy practically all habitats on Earth, from ocean deeps to the human gut, and are pivotal to the ecosystem function. They also hold a vast biotechnological potential to realize functionalities typically beyond the reach of single species, e.g. valorisation of complex resources. Rational design and modulation of communities can thus help addressing outstanding challenges in health and bio-sustainability. Yet, this remains difficult due to the complexity of interspecies interactions. Towards tackling this, I plan to combine modelling, genetics, omics and laboratory evolution to study complex microbial communities with a focus on metabolic cross-feeding. Kefir, a natural milk-fermenting community, and stable assemblies of human gut bacteria will be used as two model systems. Both systems have recently been pioneered by my lab and represent complexity relevant for real-world applications. We will first investigate the genetic and environmental factors driving metabolite secretion using high-throughput screening of natural isolates and genetic libraries. Large-scale pairwise interaction mapping and self-establishing stable sub-communities will be used to unravel higher-order interactions and to discover the principles of community assembly. Laboratory evolution will then be used to assess community stability as well as to decipher interaction mechanisms through multi-omics analyses. The experimental data on species metabolism and interspecies interactions will be used to build hybrid metabolic-ecological models for predicting effects of perturbations like species introduction and nutrient change. The applicability will be demonstrated through stable introduction of probiotic species in personalized gut bacterial communities, and by developing vitamin overproducing milk fermenting communities. The results will have fundamental implications for modulating microbial communities relevant for environment, health and biotechnology.

Keywords: microbial communities,metabolic modelling,synthetic ecology
Children’s Photography Archive: a curriculum for child-authored, multimodal citizenship education in primary schools (CHILDPHOTOARCHIVE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: United Kingdom,United Kingdom
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 150000.0
EU funding (EUR): 147194.0
Participants: 2
Project status: CLOSED

The Children’s Photography Archive (CPA beta) is the first archive in the world of its kind, featuring the photographs of child photographers. Our proposal is to test the scaling up of the CPA for the creation of evidence-based and openly accessible methodologies and learning resources for a child-authored, multimodal citizenship curriculum in primary schools. The social innovation grows out of our ERC-funded research (the 'CONNECTORS STUDY') on the relationship between childhood and public life with six- to eight-year olds that demonstrated how children connect to and produce rich multimodal stories (using text, image, sound) about their experiences of public life. Our proposal is to create and make sustainable the first-ever Children’s Photography Archive 2.0 (CPA 2.0) for citizenship education that provides educators and pupils methodologies and tools for a child-authored, multimodal citizenship education. The project seeks to (1) address the challenges faced by teachers in delivering citizenship education; (2) develop adult/educator capabilities for understanding children's visual communication in relation to citizenship; (3) provide an infrastructure to support and recognise children's visual communication. The CPA 2.0 will innovate on citizenship education by offering multimodal content and methodology created by and designed with children and teachers, and will test the scaling up of the CPA for child-authored, multimodal citizenship education in real-world settings, at the same time as providing a platform for children photographers to display their work and increase public understanding of children’s photographic forms of expression. There is an urgency to this project as we enter a critical time for Europe’s future. As such, geographically located at the edges of Europe (Greece, United Kingdom), this project will yield complex and emerging multimodal stories of what it means to grown up ‘European’ which will serve educational and cultural purposes.

Keywords: children,citizenship education,photography,live archives,multimodal photo stories,teacher education and training,europe
Novel Enablers for Cloud Slicing (NECOS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Spain,Spain,Greece,United Kingdom
Call: Cloud Computing (H2020-EUB-2017, 2017)
Start date: 2017-11-01
End date: 2019-10-31
Duration (months): 24.0
Total project cost (EUR): 1494906.25
EU funding (EUR): 1494906.25
Participants: 4
Project status: CLOSED

The NECOS project addresses the limitations of current cloud computing infrastructures to respond to the demand of new services, as presented in two use-cases that will drive the whole execution of the project. The first use-case is Telco service provider focussed and is oriented towards the adoption of cloud computing in their large networks. The second use-case is targeting the use of edge clouds to support devices with low computation and storage capacity. The envisaged solution is based on a new concept – Lightweight Slice Defined Cloud (LSDC) – as an approach that extends the virtualization to all the resources in the involved networks and data centres and provides a uniform management with a high-level of orchestration. The NECOS approach will be manifested in a platform whose main distinguishing features are: 1. The Slice as a Service –- a new deployment model. A slice is a grouping of resources managed as a whole, and that can accommodate service components, independent of other slices. 2. Embedded algorithms for an optimal allocation of resources to slices in the cloud and networking infrastructure, to respond to the dynamic changes of the various service demands. 3. A management and orchestration approach making use of artificial intelligence techniques in order to tackle with the complexity of large scale virtualized infrastructure environments. 4. Making reality the lightweight principle, in terms of low footprint components deployable on large number of small network and cloud devices at the edges of the network. The NECOS platform will be based on state of the art open software platforms, which will be carefully selected, rather than start from scratch. This baseline platform will be enhanced with the management and orchestration algorithms and the APIs that will constitute the research activity of the project. Finally, the NECOS platform will be validated, in the context of the two proposed use cases, using the 5TONIC and FIBRE testing frameworks.

Keywords: lightweight slice defined cloud,slice as a service,software defined infrastructures cloud federation,self management,artificial intelligence techniques