Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Preventing hUman intervention for incREased SAfety in inFrastructures Emitting ionizing radiation (PURESAFE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Finland,Spain,Germany,Switzerland,Germany,United Kingdom,Finland
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-02-01
End date: 2015-01-31
Duration (months): 48.0
Total project cost (EUR): 3904595.0
EU funding (EUR): 3904595.0
Participants: 8
Project status: CLOSED

The network of PURESAFE – Preventing hUman intervention for incrREased SAfety in inFrastructures Emitting ionizing radiation, aims at enhancing career development and training of 15 Early-Stage Researchers in the field of systems engineering. The program trains young researchers from multidisciplinary fields, such as mechanical engineering, software engineering and robotics for the purpose of cost-efficient life-cycle management of facilities generating ionizing radiation. The network is lead by Tampere University of Technology, world-leading training organisation in the engineering of complex systems and remote handling of scientific infrastructures. The program follows the priorities defined in the European Strategy Forum for Research Infrastructures (ESFRI) report where GSI/FAIR is listed of great scientific importance, and the European Strategy for Particle Physics of the CERN Council, where the upgrade of Large Hadron Collider (sLHC) have been defined as a priority to keep the existing high energy physics facilities and expertise at the world-class level for decades to come. The participants of the PURESAFE consortium are universities, international research organisations and industrial partners. Together they provide a stimulating environment for a broad high-quality education for young scientists. In addition to the training objectives, the project will enhance the interaction between European stakeholders to significantly increase the RTD efficiency of public and private organizations in the life-cycle management and safe operation of the infrastructures. The network answers to the increasing need of skilled and well trained researchers possessing a holistic system understanding of scientific and energy generation facilities. The trained researchers receive excellent career prospects on demanding RTD of scientific facilities, knowledge intensive products and services including RTD and decommissioning of nuclear power plants in growing markets.

Keywords: cern,gsi,training,early-stage researchers,remote handling,ionizing radiation,safety,life-cycle management,career development,research infrastructure,nuclear,industry,decommissioning
EUROCANCER STEMCELL TRAINING NETWORK (EUROCSCTRAINING)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,Austria,United Kingdom,Italy,Netherlands,United Kingdom,France,Germany
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-01-01
End date: 2014-12-31
Duration (months): 48.0
Total project cost (EUR): 3252482.0
EU funding (EUR): 3252482.0
Participants: 10
Project status: CLOSED

The recent identification of tumor initiating (TIC) or cancer stem cells (CSC) has opened a new area of research for scientists interested in cancer. Understanding the biology of cancer stem cells has already unraveled pathways and potential targets. However, accumulating data has underscored the complexity of the CSC research area and prompts hence the need for well-structured networks to provide expert platforms, rapid exchange of information to train future researchers in this new concept. 10 laboratories from 6 member states with 4 expert enterprises, all at the highest level of cancer stem cell research will unit in a European Cancer Stem Cell Training Network (EuroCSCTraining). Partners, from the public and private sector, have complementary expert experience in this new area, are active members of CSC research, and share dedication in training and dissemination. The EuroCSCTraining coordinator is one of the present coordinators of the Paris CSC Consortium and director of the Institute of PhD schools of University Paris-Diderot. The main goal of this Network is to foster translaboratory and transPhD school training in this new area of Cancer Research. The EurosCSCTraining supervisory board will bring together supervisors of the private and public sector along with representatives of PhD schools to provide eligibility criteria of recruitment, monitor training, and set up individual tutorship for PCD. The research projects on cancer stem cells will be advertised simultaneously through the EuroCSCTraining Network and the partners’ University. It is anticipated that the EuroCSCTraining network will create a multidisciplinary and multisector structure of training for a new area of research in cancer which will develop research in Europe, foster European collaborations and provide the basis to harmonise initial research training in cancer research amongst partner Institutions.

Keywords: cancer stem cell,cancer,xenografts,markers of disease,csc competence,training
European Initiative for basic research in Microbiology and Infectious Diseases (EIMID ITN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy,United Kingdom,France,Sweden,Germany,United Kingdom
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2010-10-01
End date: 2014-09-30
Duration (months): 48.0
Total project cost (EUR): 2662577.19
EU funding (EUR): 2662577.19
Participants: 6
Project status: CLOSED

The overall objective of EIMID-ITN is to train ten early stage researchers to join the next generation of world experts in the biology of infectious diseases and specifically in the mechanisms of host-pathogen interaction. The project will be carried out within the highly successful European collaboration EIMID (European Initiative for Basic Research in Microbiology and Infectious Diseases) that brings together five top research organisations in Europe active in the field of infectious diseases, including a world renowned industrial research centre. EIMID aims at reaching a critical mass on research in infectious diseases in Europe, capable of implementing a rapid and effective scientific reaction to emerging infections, and at fostering high level training in a Europe-wide collaborative network that will attract the best talents worldwide. In EIMID-ITN, ten interlinked scientific projects will tackle 1. invasive bacterial infections including meningococcal disease; 2. bacterial diarrhoeal diseases; and 3. HIV replication. The common theme throughout is the bidirectional interplay between pathogen and host in immune control vs. disease development. Selected fellows from all over the world will engage in a three-year training pathway encompassing: individual top level scientific projects (training-by-research), 1-2 stages in other EIMID labs for collaborative studies, science-related training activities such as participation to seminars, courses and congressess, common scientific meetings and networking (EIMID meeting), and common training courses in complementary and soft skills. The final goal is that of forming the leading scientists of tomorrow, possessing knowledge that goes beyond the specific scientific sectors of interest. To ensure this, the managing/training company ALTA (associated partner level 2) will implement and monitor the project progress with the help of an independent Visiting Researcher who will directly assist fellows’ progress.

Keywords: health sciences,medical sciences,medicine,immunology,infections,vaccines
Sculpting the Earth’s topography: insights from modelling deep–surface processes (TOPOMOD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy,Netherlands,Germany,Switzerland,United Kingdom,France,United Kingdom,Spain,Netherlands
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-01-01
End date: 2014-12-31
Duration (months): 48.0
Total project cost (EUR): 3790070.0
EU funding (EUR): 3790070.0
Participants: 9
Project status: CLOSED

TOPOMOD is a training project designed for a team of early-stage and experienced researchers to investigate and model the origin and evolution of topography of the continents over a wide range of spatial and temporal scales and using a multi-disciplinary approach, coupling geophysics, geochemistry, tectonics and structural geology with advanced geodynamic modeling. TOPOMOD involves 8 European research teams internationally recognized for their excellence in complementary fields of Earth Sciences, to which are associated 1 research institution, 3 high-technology enterprises, and 1-2 large multinational oil and gas companies. This unique network places emphasis in experience-based training through 15 cross-disciplinary research projects that combine case studies in well-chosen target areas from the Mediterranean, the Middle and Far East, west Africa, and South America, with new developments in tectonics, mineral physics, petrology, geochemistry, seismology, structural geology and geodynamic modeling from the deep mantle to the surface. These multidisciplinary projects altogether aim to answer a key question in earth Sciences: how deep and surface processes interact to shape and control the evolution of topography in our planet. Topography influences society, not only as a result of slow landscape changes but also in terms of geo-hazard and environmental risks. TOPOMOD will provide to 13 early-stage researchers (ESRs) and 2 experienced researchers (ERs): i) state-of-the-art concepts and leading-edge research techniques that are essential to study the behavior of complex natural systems, ii) a strong career management skills with practical courses and activities; iii) solid professional connections with industry; iv) a socially-oriented skill on environmental risks management. TOPOMOD network will create an internationally recognized leading European platform on advanced geodynamic modeling.

Keywords: topography,geomorphology,tectonics,geochemistry,geophysics
Indoor Contamination with Flame Retardant Chemicals: Causes and Impacts (INFLAME)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Belgium,Netherlands,Belgium,Sweden,Norway,United Kingdom
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-01-01
End date: 2014-12-31
Duration (months): 48.0
Total project cost (EUR): 3631363.0
EU funding (EUR): 3631363.0
Participants: 10
Project status: CLOSED

The main research goal is to further understanding of how and to what extent flame retardant (FR) chemicals used in every-day consumer goods and construction materials enter humans and of the risk to health that such exposure presents. Our vision is that this enhanced understanding will inform assessment of risk associated both with recent and current-use flame retardant chemicals, and of those under development, and ultimately lead to more sustainable approaches to meeting fire safety regulations. Our principal objectives are to discover: (1) the mechanisms via which FRs migrate from products within which they are incorporated; (2) how and to what extent such migration leads to human exposure; and (3) the effects of such exposure. To achieve our goal and objectives we will use a range of state-of-the-art techniques associated with analytical chemistry, electron microscopy, mathematical modelling, in vitro toxicology, and “omics”. The network is an interdisciplinary cooperative of chemists, biologists, physicists and toxicologists. Intersectoral aspects unite basic and applied scientists working in universities, two SMEs, a large (non-university) public sector research organisation and a government research institute. The project’s S&T objectives will be delivered through research in 3 Work Packages (WPs): viz. WP1- Migration pathways, WP2- Human exposure (pathways and monitoring), and WP3- Understanding effects of human exposure. The aim of the Training Programme is to increase the knowledge base and experience of trainees in the different research areas and to develop their transferable skills for future careers in the private sector, public sector, or the regulatory community. Six training objectives will be delivered through a suite of 6 Core Skills Areas (Research Project, Advanced Training Courses, Project Meetings, Career Development Plan, Generic Research Skills, Transferable Research Skills).

Keywords: environmental science,environmental protection,exposure assessment,health and environment (environmental protection),control of chemicals
The role of the Calcium Sensing Receptor (CaSR) in health and disease, implications for translational medicine. (MULTIFACETED CASR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria,France,United Kingdom,United Kingdom,Netherlands,Italy,United Kingdom
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-01-01
End date: 2014-12-31
Duration (months): 48.0
Total project cost (EUR): 2915948.0
EU funding (EUR): 2915948.0
Participants: 8
Project status: CLOSED

The identification of the extracellular calcium sensing receptor (CaSR) was a crucial step in understanding nutrient sensing in mammals. In mammalian organisms the CaSR has multiple roles: besides calcium homeostasis, it is involved in protection against osteoporosis, blood vessel calcification, prevention against colorectal cancer, is involved in metastasis of breast and prostate cancer cells to bone. The proposed ITN will perform basic and multidisciplinary investigations into the role of the CaSR and will provide experimental data for computational modelling. It will use holistic approaches of systems biology to gain knowledge on mechanisms of CaSR function. We will use intersectoral expertise in revealing the significance of CaSR signalling in cancer, and cardiovascular disease. The purpose of this ITN is to: • Educate and train Early Stage Researchers to become excellent scientists, enable them to gain a holistic view of their specific research area, prepare them for the challenges of working in a highly competitive environment, be it in Academia or in Industry. • Generate a systems biology model for CaSR-dependent signalling in order to find innovative therapeutic approaches and interventions for the natural and synthetic ligands of the CaSR. • Establish long lasting interdisciplinary and intersectoral cooperation among basic, clinical and applied researchers, working on the CaSR to strengthen the European Research Area. Being in a research environment that examines the role of one single molecule in many different tissues (e.g. kidney, intestine, blood vessels) and pathologies (cancer and vascular calcification), will increase the awareness of the young researchers for a holistic approach in understanding CaSR-related pathophysiology. Continuous comparison of the function of the CaSR in systems studied by their fellow ESRs, will sensitize the young researchers for the complexities of biomedical research and advantages of multidisciplinarity.

Keywords: cancer research,molecular cellular biology,systems biology,vascular calcification,parathyroid,colon,breast,kidney,calcium,mouse models,g-protein coupled receptor,replication licensing
Urban, peri-urban and regional food dynamics: toward an integrated and territorial approach to food (PUREFOOD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,United Kingdom,Italy,Latvia,United Kingdom,Brazil,Uganda
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2010-12-01
End date: 2014-11-30
Duration (months): 48.0
Total project cost (EUR): 2886380.0
EU funding (EUR): 2886380.0
Participants: 7
Project status: CLOSED

Increasing urban food-related health and environmental problems are raising an urgent need for action. Current agrifood studies tend to neglect the broader societal and spatial impacts of food. PUREFOOD will reduce the high knowledge and skills deficit that negatively affects the capacity to deliver political and developmental solutions related to food security, public procurement, health and sustainable regional development. Through its innovative methodology, the interdisciplinary courses, private and public sector involvement, the holistic conceptualization of sustainable food and the formation of Communities of Practice (CoPs) that include actors at all stages of the food chain, PUREFOOD contributes to Commission’s aim to deal with economic, social and environmental policies in mutually reinforcing ways. We study an alternative geography of food, based upon three emerging trends; sustainable food supply chains, public sector food procurement practices and (peri-)urban food strategies. Each is topic of a scientific WP with 4 ESRs in individual research projects using case study methodology. The related training aims to transfer disciplinary scientific knowledge and skills between complementary groups, leading to a coherent frame of basic and advanced scientific, professional and host institute training modules, and to interactively develop scientific and professional knowledge and skills through ‘learning-by-doing’ in CoPs for each WP. PUREFOOD consists of 7 full academic partners and 8 associated partners (private sector and socio-economic partners). PUREFOOD’s coordinator has ample experience in managing international interdisciplinary research and training projects. The commitment of private and public organisations and NGOs as associated partners illustrate the timeliness of our proposal and impact to the career perspectives of the ESRs. Completed CDPs give access to a PhD degree at every partner university.

Keywords: sociology,human geography,economic geography,management studies,ethnography,governance,socio-economic research,agro-food studies,food policy & planning,urban and regional planning,regional studies
An early stage training network in enabling technologies for GREEN radio (GREENET)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,United Kingdom,Italy,Greece,Portugal,France,Italy,Germany,Germany
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-01-01
End date: 2014-12-31
Duration (months): 48.0
Total project cost (EUR): 4230443.93
EU funding (EUR): 4230443.93
Participants: 10
Project status: CLOSED

Current 4G vision envisages higher data rates and multi standard radio interfaces to provide all users with a continuous seamless connection. The large number of foreseen devices coupled with the surge in power requirements for future emerging handsets raises significant challenges in terms of: i) reducing the energy consumption; and ii) reducing the amount of electromagnetic radiations. GREENET targets the following main objectives: 1. Recruitment of ESRs with the clear and long-term objective to conduct top-notch research and to pursue research excellence at the national, European, and international levels. 2. Develop training and career plans that are personalized as possible to meet the needs and desires of each ESR. 3. To allow the ESRs to understand and address key research challenges on energy efficient GREENET communications, that form pivotal societal and economic concerns for Europe within the mid-to-long term. 4. Offer to each ESR top-level training and research programs with the twofold objective to reinforce and corroborate their own background, as well as to complement this with active participation in a multi-disciplinary network of research scientists. 5. Complement the typical competences of “applied research” with aspects related to project management, intellectual property rights, writing of patents, presentation and communication skills, writing of technical papers, exploitation of technical results and creation of start-up companies, etc. 6. Guide and help the ESRs to build the bridge from academia to a remarkable and untactful professional career in either the private or public sectors.

Keywords: green radio,energy efficient wireless networks,cooperative communications,cognitive networks
Metabolic Flux Analysis and Cancer (METAFLUX)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,Israel,Spain,Switzerland,Hungary,United Kingdom,Austria
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2010-11-01
End date: 2014-10-31
Duration (months): 48.0
Total project cost (EUR): 4384122.96
EU funding (EUR): 4384122.96
Participants: 9
Project status: CLOSED

The post-genomic era has been driven by the development of technologies that allow the function of cells and whole organisms to be explored at a molecular level. Metabolomics is concerned with the measurement of global sets of low-molecular-weight metabolites, which represent important indicators of physiological or pathological states of organisms. Such profiles provide a more comprehensive view of cellular control mechanisms in man and animals, and raise the possibility of identifying surrogate markers of disease. Metabolomic approaches use analytical different techniques to measure populations of low-molecular-weight metabolites in biological samples. To decipher large metabolic data sets advanced statistical and bioinformatic tools are commonly employed. Although metabolomics has only recently emerged, dynamic profiles generated in Metabolic Flux Analysis (MFA) are becoming increasingly important to analyse biological networks in a quantitative manner and as part of systems biology approaches. MFA allows us to probe hypotheses by incorporating a priori biological knowledge to provide practical descriptions of observed cell behaviours, and to characterise the outcome of network perturbations. Flux analysis is of particular value for the diagnosis, differentiation and elucidation of mechanisms in cancer. This was recognised as early as 1924 by the Nobel Prize winner Otto Warburg who attributed cancer to a change in cellular energy production. This theme has experienced a revival in recent years through research, which has established mitochondrial dysfunction as a major mechanism in cancer. This proposal seeks funding for a truly interdisciplinary European consortium to train researchers to exploit the gains of new technologies provided by metabolic flux analysis in the context of cancer with a mixed focus on new developments and applied end-points.

Keywords: health sciences,oncology,cell biology,biochemical technology,systems theory,clinical analysis,molecular markers and recognition