Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The acrylamide free Superabsorbent Polymer for agriculture water footprint reduction (Polygreen)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

PolyGreen is a Superabsorbent Polymer (SAP) specifically designed to reduce water consumption in agriculture, being able to absorb excess water provided by rain or irrigation up to 200 times its weight and slowly release it during dry period, allowing to reduce the need of water by 50%. PolyGreen is the only SAP for agriculture that does not contain acrylamide, which is a carcinogenic material (Group B2 Probable Human Carcinogen) and will be soon banned from agriculture applications; it is completely biodegradable and behaves as an excellent soil improvers; it has a double durability and reduced price with respect to competitors. PolyGreen is a certified technology validated in the field but currently only targeting domestic or high-end applications, due the high price of 8 €/kg and handicraft production. The aim of the initiative is to optimize the production, reach a price of 3€/kg, validate and launch the product on large scale and high-water demanding industrial crops. To this aim NEST needs to: 1) optimize the supply chain and the manufacturing process; 2) validate and certify the application in specific industrial crops and validating the product price; 3) implement a first industrial manufacturing line of 1750 tons/year then scaled up of 5 times; 4) close agreements with investors and technological partners to support the investment. These assumptions will be validated and confirmed during the feasibility study. SAP market in agriculture applications is estimated to reach a global value of 327.4 million USD by 2023, of which 30% represented by EU market considered as the Total Addressable Market (TAM) equal to 98 million €/year by 2023. PolyGreen targets to enter the mass market of industrial crops market (1 or 2 crops) in 2021 with a production capacity of 1750 tons then expanded to 10.000 tons, reaching the break-even of the 6.8 M€ investment in 2024. The turnover will reach 30 MEuro, EBIT 6.7 M€ and a cumulated cash flow of 7 M€ in 2025.

Keywords: superabsorbent polymers sap,water footprint reduction in agriculture,acrylamide free,soil improvement
climote Advanced Demand Management of Heating and Cooling (climote)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Ireland
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2014, 2014)
Start date: 2015-04-01
End date: 2015-09-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Climote is a multi-award winning remote controlled home heating hub. With Climote, you can control your home heating from anywhere using our full suite of remote services. We want to create an advanced demand and management tool for domestic heating and cooling. This tool, based upon Climote’s home heating hub, will help delivers Europe’s goal of a low carbon economy by allowing advanced demand management of heating and cooling to help prevent curtailment of European wind farms. Using the hub we can collect information about the household’s energy usage and create a profile for that household. This profile shows what energy is used for and when. We can then schedule certain regular and predictable tasks to happen automatically. By removing the need for manual control, not only do we make people’s lives more convenient, but we also remove human error from the equation, resulting in less energy wastage, Furthermore these tasks can be scheduled to take place at certain times, such as during off peak hours when the cost of energy is lower and there is excess renewable energy on the grid. This has both the advantage of reducing energy waste, and of shifting consumption to renewable sources. Domestic homes account for about 27% of Europe’s total energy consumption. Of this the majority is made up of space and water heating and cooling which is responsible for over 80% of domestic household emissions. By networking the households together into a single central scheduling structure, we can significantly reduce the CO2 emissions across Europe. All this can be provided free of cost to the end users thanks to our business model which makes use of reselling energy credits.

Keywords: low carbon,curtailment wind farms,domestic heating and coolinh
Science, Technology, and Society Initiative to minimize Unwanted Catches in European Fisheries (MINOUW)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: Research and Innovation actions
Countries involved: Italy,Iceland,Spain,Spain,Spain,Italy,Israel,Italy,Belgium,Greece,Finland,Norway,Greece,United Kingdom,Portugal
Call: Towards a gradual elimination of discards in European fisheries (H2020-SFS-2014-2, 2014)
Start date: 2015-03-01
End date: 2019-02-28
Duration (months): 48.0
Total project cost (EUR): 6239622.38
EU funding (EUR): 5904029.5
Participants: 18
Project status: CLOSED

The complexity of the problem of banning discards and bringing all unwanted catches to land makes it necessary to follow a multi-actor approach, whereby scientists, fisheries technologists, fish producers and NGOs work collaboratively to provide the scientific and technical basis to achieve the gradual elimination of discards in European marine fisheries. The project’s overall objective is to minimise unwanted catches by incentivising the adoption of fishing technologies and practices that reduce pre-harvest mortality and post-harvest discards, while avoiding damage to sensitive marine species and habitats. The general approach is based on technical/technological and socioeconomic solutions on a case-by-case analysis of the main types of European fisheries. The project will analyze existing and potential discard-mitigating innovative technologies in workshop roundtables with participation of fishers, technologists and scientists. The technologies selected will be tested in field trials to experimentally assess their efficiency: among other, improved precatch identification with observational technologies and pre-harvest loss reduction by gear modification and switching to light impact gear. The results will be analyzed in terms of technological advances, marketability and cost-benefit analysis. Other actions included in the project are social and economic instruments to incentivise selective fishing and discourage discarding practices, such as ecolabelling, fisheries certification and promoting awareness among industry and consumers, and mathematical modelling of ecosystem effects of unwanted catches reduction.

Keywords: multi actor approach,stakeholder participation,responsible fishing
Ensured Randomness Integrity in Device-Independent Networks (ERIDIAN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-07-01
End date: 2017-12-31
Duration (months): 18.0
Total project cost (EUR): 149925.0
EU funding (EUR): 149925.0
Participants: 1
Project status: CLOSED

ERIDIAN will develop a market-ready quantum random number generator for Device Independent (DI) Quantum Cryptography (QKD), which offers the best possible security guarantees. The prototype developed in ERIDIAN will enable major industrial players to make DI QKD a commercial reality. Current, classical cryptography is based on the assumed difficulty of certain mathematical problems and thus insecure against future mathematical advances and against quantum computers. Quantum cryptography gives future-proof security guaranteed by physical laws, but until now is very difficult to commercialise: the user must trust the communications equipment and its supplier, making a mass-market approach impossible. The DI approach to quantum cryptography uses strong, directly observable data correlations, technically a "loophole-free Bell Inequality Violation" (BIV), to guarantee security. Because the security (or not) of the connection is transparent to the user, there is no need to trust the communications provider, greatly facilitating commercialisation. The first loophole-free BIVs were demonstrated in 2015, using laboratory-grade random number generators developed in the ERC starting grant AQUMET. ERIDIAN will advance to the prototype stage this randomness generation technology, a critical element of the BIV and thus a requirement for the DI approach. The availability of a commercial-grade randomness source suitable for BIVs will allow industrial actors such as telecommunications providers to enter the DI field and offer solutions to a broad range of customers.

Keywords: quantum cryptography,device independent communications security,bell inequality violation,random number generation
Translational Brain Imaging Training Network (TRABIT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Austria,Germany,Germany,Switzerland,Switzerland,Belgium,Belgium,Netherlands,Netherlands,United Kingdom,United Kingdom,Denmark,United Kingdom,Denmark
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2017-10-01
End date: 2022-09-30
Duration (months): 60.0
Total project cost (EUR): 3938655.6
EU funding (EUR): 3938655.6
Participants: 20
Project status: CLOSED

Brain diseases account for one third of the overall disease burden in Europe, and their already significant cost to society is expected to further escalate as a result of the aging European population. In recent decades, medical imaging techniques such as computed tomography, ultrasound, and especially magnetic resonance imaging have gained a central role in the clinical management of disorders of the brain. A fundamental bottleneck in translating the wealth of information contained in medical images into optimized patient care is the lack of computational tools to reliably and accurately analyze the available images. Combined with the sheer volume of data acquired on a daily basis, the current dearth of computational tools means that most of the relevant information contained in today's clinical brain scans simply remains unused. In an interdisciplinary and intersectoral joint effort of computational scientists, clinicians, and the industry in the field of neuroimaging, the "Translational Brain Imaging Training Network" (TRABIT) aims to provide a new generation of innovative and entrepreneurial early-stage researchers (ESRs) to bring quantitative image computing methods into the clinic, enabling improved healthcare delivery to patients with brain disease. The proposed network brings together internationally leading groups in biomedical image computing; some of Europe's most renowned research hospitals; and important players from the medical imaging industry. Through this network, each of TRABIT's ESRs will have access to the most relevant experts from industry, academia, and hospitals, as well as large collections of clinical neuroimaging data, facilitating the evaluation of the true clinical relevance and impact of the investigated computational methods. A commonly adopted rapid-prototyping software environment will facilitate testing, demonstrating the developed tools in hospital environments, and disseminating the obtained models and methods.

Keywords: medical image computing,neuroimaging,brain diseases
Super-resolution optical microscopy of nanosized pore dynamics in endothelial cells (DeLIVER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Australia,Germany,Germany,Hong Kong,Norway,Belgium,Sweden,Norway,France,France,United States,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-01-01
End date: 2022-06-30
Duration (months): 54.0
Total project cost (EUR): 3728513.16
EU funding (EUR): 3728513.1599999997
Participants: 14
Project status: CLOSED

DeLIVER will train a new generation of ESRs in the development and application of newly developed high speed and high resolution imaging tools in biomedical research. ESRs will be cross-pollinated with concepts and skills in physics and biomedicine, in particular in super-resolution optical imaging (a.k.a. optical nanoscopy), analytical image reconstruction, and optical micro-manipulation methods. These skills are applied to reveal for the first time the function and dynamics of nanosized pores in endothelial cells (EC) that present the main barrier between the blood and vital organs for human physiology, such as the liver, brain, kidneys, and the eyes. Very little is known about the extremely important physiological function of these unique structures and their role in the transfer and/or clearance of metabolites and pharmaceuticals to vital organs. The current generation of optical nanoscopes, however, is rather slow and can only be applied to isolated, typically fixed (i.e. dead) cells rather than biomedically relevant tissues. Also, newcomers to the field need to familiarize themselves with a whole new set of potential problems that might arise in the use of optical nanoscopy, such as image reconstruction-related artifacts to name just one example.This is an area of research where European enterprises are very active. Excellent training in new scientific and complementary skills, combined with international and intersectoral work experience, will instil an innovative, creative and entrepreneurial mind-set in DeLIVER's ESRs, maximising economic benefits based on scientific discoveries. These specialised, highly trained, and mobile ESRs will have greatly enhanced career prospects. The training in novel physical methods with highly relevant experience in the biomedical sciences will allow them to confidently navigate at the interface of academic, clinical and private sector research.

Keywords: optical nanoscopy,high speed optical imaging,nanopores,cellular fenestrations,nanolipoproteins,lipid rafts
Disempowering Cyber-Attackers (CYBER-PDR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel,United Kingdom
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 3532500.0
EU funding (EUR): 2472750.0
Participants: 2
Project status: CLOSED

Cyber threats have evolved from relatively harmless to powerful dangers to businesses with implications on the bottom line, reputation, privacy & more. In its 2019 Global Risk Report, the World Economic Forum lists cyber threats as #4 in terms of likelihood, & #7 in terms of impact. According to an Accenture report the accelerating cost of cybercrime in 2017 was 23% more than in it was in 2016 & it’s costing organisations, on average, €10.5M.With our ground-breaking CYBER-PDR solution, the business opportunity is clear. We anticipate potential annual revenues of €87M by 2022. Illusive enables the most effective & earliest attacker detection attackers by stopping lateral movement, & empowering rapid triage through risk-awareness & real-time attack intelligence. Illusive’s technology is scalable, noiseless, easy to operate, & invisible to attackers. Illusive frustrates attackers’ lateral movements toward crown jewels in several important ways, thereby altering reality to prevent, detect, & respond to attacker movement. The team is 90 strong globally, consisting of top cyber-attack specialists & pioneering cyber technology entrepreneurs with decades of collective experience in cyber warfare & cyber intelligence. Prior to establishing Illusive Networks, Ofer Israeli was an entrepreneur in residence at Team8, Israel’s leading cybersecurity think tank & company creation platform. The overall aim of this project is to expand into the EU market. Our commercialisation activities will include: 1) Forge a strategic alliance with Cybertrap & market a shared development with their decoy; 2) Implement 960 demos & 160 POCs, part of which will be fortune 500 companies in banking, & insurance across Europe; 3) Build a pipeline in Europe; 4) Scale up operations; 5) Attend & speak at strategic events & tradeshows to build exposure in Europe; 6) Obtain all relevant regulatory & compliance certifications, & register additional patents & trademarks.

Keywords: cyber threat,cyber attacks,cyber security,protect,detect,respond,deception,decoy,attack surface,manager,lateral movements,crown jewels,cyber technology,altering reality
Reward revisited: Towards a comprehensive understanding of motivational influences on human cognition (REMOTIVATE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Belgium
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-10-01
End date: 2021-07-31
Duration (months): 70.0
Total project cost (EUR): 1257000.0
EU funding (EUR): 1257000.0
Participants: 1
Project status: CLOSED

Motivation is a central topic in psychology, not least because of its strong interrelation with other psychological concepts, as well as with various clinical conditions. Beyond globally energizing behavior, recent studies have begun to describe effects of extrinsic reward on various specific cognitive operations like conflict resolution, inhibitory control, and memory formation. Intriguingly, these functions appear to be disturbed in a number of neurological and psychiatric disorders, like attention-deficit hyperactivity disorder, addiction, and Parkinson’s disease. On the neural level, these disorders have been related to disturbances in the dopaminergic (DA) and/or the noradrenergic (NA) system, which are the very same systems that are also thought to be vital for the cognitive benefits of reward observed in the healthy mind. Despite this central, probably interrelated, role in the healthy and the diseased mind, our understanding of how exactly reward impacts specific cognitive operations is still rudimentary, both on the level of psychological theory as well as concerning the underlying neural mechanisms. The aim of this proposal is to develop a novel unifying conceptual and neural framework of how reward influences human cognition. To achieve this goal, it is essential to extend our conceptual understanding of the nature of such reward effects by integrating additional interrelated factors, such as stimulus saliency, different cognitive-control and response modes, and the influence of irrelevant information. In order to match this conceptual progress at the neuromechanistic level, it is critical to employ optimized neuroimaging methods that allow for a reliable, yet non-invasive investigation of neural activity in the source and target regions of the DA and NA system. Given the critical role of motivation in the healthy and the diseased mind, the results will provide new valuable insights for both basic and applied psychological and neuroscientific research.

Keywords: neural basis of motivation,cognitive control,memory,emotion,fmri
Delivery of PULmonary Therapeutics through TARgetted Delivery using Phononics (PULTAR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-07-01
End date: 2016-12-31
Duration (months): 18.0
Total project cost (EUR): 149791.0
EU funding (EUR): 149791.0
Participants: 1
Project status: CLOSED

According to the WHO 235 million people suffer from asthma and 64M people have chronic obstructive pulmonary disease, leading to 3M deaths per year worldwide. The cost of treating patients with all forms of lung disease is ~ €380B p.a., leading to the loss of >50M DALYS. Generally, patients with such respiratory diseases are treated by inhalation of medicines within aerosols, where the therapy (including medicine or biologics used in gene therapy) can be targeted directly to the lung. The accepted wisdom is that such pulmonary delivery requires aerosol droplet sizes of between 1 and 5 μm. We have now shown that by using a new ultrasonic technology, we can create monodisperse aerosol droplets, which could be used for therapeutic delivery of medicines, genes and RNA to specific regions in the lungs. In one strand of the work we aim to demonstrate that this precise nebulisation technology improves the efficacy of treatment through enhanced drug uptake. In a second strand, we will demonstrate selective targeting of different tissue types in the lungs. For example, the epithelium in cystic fibrosis patients is currently extremely difficult to access leading to limitations in the amount and quality of data obtained for pre-clinical and clinical gene therapies. Similarly, targeting vascular cells is an appealing treatment for patients with pulmonary arterial hypertension, although, again, effective delivery necessitates that the therapeutic system transits defined and substantial anatomical barriers. The overall aim is to demonstrate that this new technology can define routes to new therapies, improve clinical outcomes and reduce healthcare costs. To achieve this we will develop a prototype nebuliser based upon proprietary technology and show that different medicines and gene therapies can be delivered effectively to the lungs of a model mouse. We will also start to build a commercial team and work closely with industry to deliver impact and innovation to the market.