Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Identifying how Evolution exploits physical properties of tissues to generate the complexity and diversity of Life (EVOMORPHYS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-08-01
End date: 2025-07-31
Duration (months): 72.0
Total project cost (EUR): 2499070.0
EU funding (EUR): 2499070.0
Participants: 1
Project status: SIGNED

My project focuses on answering one fundamental question: what are the drivers of Life’s morphological complexity and diversity? I claim that this question can only be addressed by a Newtonian-Darwinian synthesis that considers how Evolution exploits the physical properties of living matter. I will investigate how the evolutionary process explores the phase space of possible interactions between physical (mechanics, reaction-diffusion) and biological (cell signalling, proliferation, migration) processes and generates configurations that compute functional phenotypes. In particular, I will combine experiments in biology and physics, as well as mathematical models and Artificial-Life (ALife) numerical simulations. The latter will be based on physics’ first principles, symmetry-breaking processes and a genetic algorithm. First, I will investigate how geometry affects signalling by (i) imaging the embryonic development of colour patterns and skin geometries of multiple squamate species with various scale-to-colour pattern correspondences, (ii) generating CRISPR/Cas9 scaleless mutants in two lizard species to study the effect of skin 3D geometry on colour patterning, and (iii) performing ALife experiments to explore how the evolutionary process can modify signalling events and exploit geometry to generate new patterns. Second, I will analyse how growth can affect geometry by (i) performing in-silico experiments where coupling between growth and morphogenesis is systematically explored and (ii) evaluating how much the in-silico model captures morphologies generated with physics laboratory experiments using 3D layered polymeric gels. Third, I will build a Newtonian-Darwinian framework by coupling geometry, signalling, growth and mechanics in extensive open-ended ALife experiments. The results of the EVOMORPHYS project will constitute a novel framework for understanding how Evolution exploits physics to generate the morphological diversity and complexity of Life forms.

Keywords: evolution,artificial life,numerical simulations
CivDrone – fast, remote and reliable staking solution (CivDrone)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-09-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Every construction work follows precise blueprints and instructions. When the project plan is implemented in the real-world site, the land surveyor places physical markers, also known as stakes, according to the general contractor’s construction plan. The staked reference points include instructions of the works that needs to be done – for instance how deep to dig in order to place the pipeline in the right depth. Most construction tasks require physical staking, even simple tasks such as placing the road railing and sidewalk. Physical staking is a laborious and time-consuming job that presents multiple drawbacks such as slow measurement and staking process and manual marking mistakes, leading to higher upfront and downstream costs. CivDrone’s innovative staking mechanism is installed on an enterprise drone equipped with RTK system. The drone flies autonomously to the desired coordinates and inserts the stakes in the ground. Tags contain all relevant information for the work of the general contractors, so the constructors will be able to get all the tasks and updated blueprints directly on their own smartphone/tablet when moving in the working field. During the phase 1 project, a go-to-market strategy and a supply chain will be established, as well as further development plan will be drafted. The Phase 2 innovation project will allow for engineering and development of the navigation system and staking mechanism to achieve higher accuracy and functionality, scale up of production to produce mechanism and stakes for pilot trials with potential construction, train, road, and pipeline companies.

Keywords: autonomous staking,rfid,drone,staking mechanism,construction instructions
Innovation Management Support for SMEs (Innosupport)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Germany,Germany
Call: INNOSUP (H2020-Adhoc-2014-20, 2014)
Start date: 2014-07-01
End date: 2014-12-31
Duration (months): 6.0
Total project cost (EUR): 49000.0
EU funding (EUR): 39200.0
Participants: 2
Project status: CLOSED

The general objective of the described actions is to contribute to smart growth in the European Union by increasing the efficiency and effectiveness of investments in research, development and innovation and by contributing to a better and more efficient connection of actors along the innovation chain. To achieve the above mentioned objectives the proposed grant shall: a) Identify bottlenecks to the creation of economic impact in companies benefitting from grants by Horizon2020's SME instrument and address these bottlenecks with the help of capable coaches. This service to beneficiaries of the SME instrument in the context of a giving project is called 'Key account management'. b) Increase the efficiency and effectiveness of innovation processes in small and medium sized enterprises with significant innovation activities that could potentially become beneficiaries of European support to research and innovation but would not have effective access to consulting services for innovation management. This service, provided independently from a specific innovation project and focussing on a company's innovation management system, is called 'Enhancing the innovation management capacity of SMEs

Keywords: innovation management
LArge Passenger Aircraft Reliable Touch Screen. (LAPARTS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Belgium
Call: Touchscreen control panel for critical system management functions (H2020-CS2-CFP02-2015-01, 2015)
Start date: 2016-09-01
End date: 2023-09-30
Duration (months): 85.0
Total project cost (EUR): 2851947.0
EU funding (EUR): 1996362.9
Participants: 1
Project status: SIGNED

The purpose of LAPARTS is to develop a Touch Screen Control Panel (TSCP) system that can host all functionalities currently hosted on the Overhead Control Panel (OCP). The OCP today consists of numerous electro-mechanical switches, buttons, knobs and annunciators connected with discrete wires to the aircraft systems. The current state of art of OCPs has several issues with ergonomic, economic and environmental implications. The TSCP system will address these issues while hosting highly safety critical functions. The TSCP system will be compatible with up to catastrophic failure conditions and will secure the control chain from the touch sensor to the controlled system and back to the display. In a first phase (ending Aug. 2019), TSCP prototypes will be integrated and evaluated in an enhanced cockpit simulator and potentially flight test platforms, targeting an evolution of the cockpit for existing aircraft. In a second and conditional phase (ending end of 2023), the TSCP will be integrated and evaluated in a disruptive cockpit simulator, targeting a revolution of the cockpit for deployment in future aircraft at the longer term. The TSCP will be developed following a user centred design methodology paying a lot of attention to human factors and end user interests. LAPARTS will adopt a sophisticated combination of projected capacitive and force sensing technologies in the touch screen in order to achieve the required safety levels while preserving user comfort. LAPARTS will contribute to WP3.1 of the LPA IADP (tactile HMI), including weight reduction, manufacturing and usage cost reductions and recommendations towards the certification authorities. LAPARTS will also advance touch screen technology for use in turbulence conditions and safety critical applications.

Keywords: cockpit,display,touch screen,pcap,force sensing,human factors,safety,overhead control panel
Pioneering the Digital Future for Omnichannel Retail Managers (PERFORM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Austria,Ireland,Austria,Germany,Germany,Ireland,Ireland,Sweden,Poland,Netherlands,Netherlands
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-01-01
End date: 2022-12-31
Duration (months): 60.0
Total project cost (EUR): 3869128.44
EU funding (EUR): 3869128.44
Participants: 15
Project status: CLOSED

The overall goal of PERFORM is to establish a European training network to prepare the next generation of Digital Retail Managers. Established Business Models need to be revised as customer behaviour is changing. Customers no longer prefer online or instore purchasing but switch between channels to suit their own personal requirements. Innovative digital technologies such as Internet of Things, Big Data, advanced analytics as well as augmented reality novel payment systems and visualisation concepts can create a unique and individual customer experience. With PERFORM we create a coherent customer experience for Digital Retail by combining online and traditional offline retail to an integrated Omnichannel system addressing the following 4 research objectives: ● Develop sustainable business models for the Digital Retail sector. ● Examine approaches to increase the customer experience along the customer journey. ● Investigate how technologies can be used to provide innovative Digital Retail services and create a unique customer experience. ● Develop knowledge base on Digital Retail operations and analytics. We will assist the Digital Retail sector to realise valuable strategic options for local EU retailers related to the Single Digital Market. PERFORM builds an interdisciplinary network including various disciplines (such as technology, business and behaviour science) and will educate Early Stage Researchers. PERFORM provides a timely response to the increasing need from the retail sector for highly skilled graduates and researchers, which are highly sought after in industry and academia. We offer exciting career perspectives based upon existing and future job profiles within the digital retail industry. The research programme of PERFORM will develop new methods, concepts and technology implementations for Digital Retail. Both academic and non-academic participants of PERFORM will contribute to strengthening the Innovation Capacity in Europe.

Keywords: digital retail,connected retail,business models,omnichannel management,mobile commerce,payment systems,retail operations,customer experience,digital marketing,digital retail legal framework
Inequality, urbanization and Territorial Cohesion: Developing the European Social Model of economic growth and democratic capacity (COSHMO) (COHSMO (Former Hans Thor Andersen))

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Research and Innovation actions
Countries involved: Austria,Italy,Greece,Lithuania,Poland,United Kingdom,Denmark
Call: Spatial justice, social cohesion and territorial inequalities (H2020-SC6-REV-INEQUAL-2016, 2016)
Start date: 2017-05-01
End date: 2021-10-31
Duration (months): 54.0
Total project cost (EUR): 3748335.0
EU funding (EUR): 3748335.0
Participants: 7
Project status: CLOSED

The principal aim of COHSMO is to investigate the relation between socio-economic structures of inequality, urbanization and territorial cohesion, and how territorial cohesion at different European scales affect economic growth, spatial justice and democratic capacities. The way that public, private and civil society stakeholders counter or cushion spatial injustice varies across localities in Europe. In common, is the need to develop the institutional capacities for place-based collaboration and democratically mobilize communities for policy development and adaption. Although location and place have gained attention in European policy and the theoretical thinking informing regional development policies, it is argued in COHSMO that we need to change our orientation in the direction of making place-informed theories and policies instead of applying existing theories and policies on places. This will be done by providing a cross-case analysis and assessment of territorial cohesion within three different cases in each of the seven national partner contexts based on a mixed-method and locality-sensitive approach. The fieldwork will focus firstly on the relation between policy instruments and local experiences of territorial cohesion, and secondly on how “social investment strategies” relate to territorial cohesion and local conditions. Moreover, the project engages in an assessment of spatial development policies at different governance scales to map the impact of different policy instruments in the fight against spatial inequality and spatial injustice. COHSMO is innovative in its differentiated approach to how location matters, and coupled with its conceptual advances COHSMO will develop groundbreaking policy recommendations in relation to sustainable economic growth, spatial justice and democratic capacity. Because they stem from location-sensitive and cross-contextual research, such recommendations will make it possible to develop the European Social Model.

Keywords: spatial inequality,european social model,territorial cohesion,social investment
Testing Advanced Basic Structures with novel Low-Cost Solutions (TABASCO)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Spain,France
Call: Rear End Structural Test Program – Component & Subcomponent tests (H2020-CS2-CFP09-2018-02, 2018)
Start date: 2019-10-01
End date: 2022-07-31
Duration (months): 34.0
Total project cost (EUR): 1606668.75
EU funding (EUR): 1124668.13
Participants: 2
Project status: CLOSED

The work of this consortium will be the experimental verification by means of a test campaign (Level 2-3) of a novel design, material, structural an industrial process for the Advanced Rear End (ARE) demonstrator included in WP1.2 on Platform 1 of Cleansky project. This project has three research objectives: 1) Implement new methodologies to support, validate and correlate Virtual Testing Models. 2) Design and manufacture innovative tool and test setups to maximize the instrumented area to better identify the boundary conditions of the test based on Absolute Accurate Methodology. 3) Research advanced instrumentation solutions to improve quality of the results reducing cost and time in future aircraft certification test campaigns. To achieve these objectives, the following IT tools, methodologies and novel instrumentation will be researched: a. Applus E-Testing© monitoring service to follow up the metrological data in real-time using a simple internet browser. This technology allows correlating real-time video recording and measured data (load, stress…) with FEM predictions. b. CAETest Bench for accurate representations of material behaviour. c. Thiot CESAR© software to simulate gas gun performance to reduce the initial test trials to adjust the pressure and other launcher parameters. d. Applus Absolute Accurate Methodology e. Faster and more accurate optical Full Field stress measurement based on Match ID Technology that allows improving Digital Image Correlation uncertainty and advanced algorithms to allow measurements in Real- time during the test. f. Innovative methods to improve crack/de-bonding onset and propagation detection by: i. Acoustic Camera contactless metrology from GFAI TECH GmbH to quickly hot-spot de-bonding and first Failure cracks ii. Structural Health Monitoring to control the damages of the structures being tested with the support of Universidad Politécnica de Madrid g. Improved wireless Strain gauges taking advantage of Applus IoT Lab capacities to reduce the test setups time and complexity and allow Structural Monitoring of the tested part. h. Residual Energy “live” sensor based on instrumented projectile catchers developed by Thiot

Keywords: virtual test structural material composite fem monitoring database card validation verification correlation boundary conditions digital image acoustic camera ultrasonic thermography wireless sensor
Airborne Artificial Intelligence for more efficient, safer and sustainable inspection and surveying of energy industrial areas (MYRIAD)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Iceland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-02-01
End date: 2019-05-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The energy industry relies on inspection and surveying activities to evaluate the condition of infrastructures and land surfaces. However, these activities are mainly performed manually by in-person missions, a time-consuming and costly process that may yields to incomplete and poor-quality results without possibilities of forecasting, as well as posing a safety threat to personnel performing these tasks. Towards that direction, drones - technically described as Unmanned Aerial Vehicles (UAVs) - are evolving beyond their military origin extending their offerings to commercial sectors. Companies are starting to realize that they constitute not only a replacement to time-consuming, costly and dangerous in-person missions but also an excellent alternative for accurate real-time data collection. With MYRIAD we disrupt commercial drones’ market by introducing an innovative drone-based inspection and surveying system to be applied as valuable business tool in a number of energy sectors. By combining the efficiency, cost benefits and safety of UAVs with insightful aerial data and powerful software with AI, MYRIAD enables decision making for our customers based on real-time anomalies detection and forecasting (Airborne Artificial Intelligence). With MYRIAD drone we propose a 24/7 fully autonomous inspection and surveying able to reduce associated workload and operational costs at 50-75% compared to traditional manual methods while minimizing personnel risks. Furthermore, through our proprietary software we offer on-demand acquisition of high-quality aerial data and real-time analysis, interpretation and forecasting of anomalies - powerful datasets – to guarantee the successful operation of energy related companies.

Keywords: inspection,operations and maintenance,forecasting,remote sensing,geo information,spatial data analysis
Multi-analyte liquid biopsy to monitor tumor genomic evolution and therapy response in advanced Prostate Cancer (MultiLQB-PC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-03-28
End date: 2024-03-27
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: CLOSED

Metastatic prostate cancer (mPC) is a lethal disease. Androgen deprivation therapy is the mainstay of patient care. In addition, DNA repair defects is a novel therapeutic target in mPC. However, resistances invariably arise, triggered most of the times by tumor genomic evolution. Liquid biopsy has emerged as a tool to non-invasively profile tumor genomics over time. Beyond circulating tumor DNA (ctDNA) and circulating tumor cells (CTC), small extracellular vesicles, known as exosomes, have been identified to contain tumor genomic material. Over the last years, I have developed a method to pursue analysis of tumor genomic material from exosomes at a very low cost. The analysis of exoDNA/RNA is a promising tool that represents a new non-invasive, sensitive and very informative new method for PC monitoring. In this project, I aim to integrate the genomic analysis of exoDNA/RNA together with ctDNA and CTCs in advanced PC to:1) Identify prognostic signatures for clinically-relevant patient stratification; 2) Define circulating predictive signatures of drug response/resistance; and 3) Validate biomarkers of therapy response for selection of subsequent lines of treatment. Therefore, this fellowship would allow me to take a significant step towards the implementation of this new technology in the study of mPC genomics and mechanisms of response/resistance to novel targeted drugs. Furthermore, I will be able to integrate my research into clinical trials and, ultimately, impact personalized patient care.

Keywords: prostate cancer,liquid biopsy,personalized medicine