Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Carbon – Ice Composite Materials: Water Structure and Dynamics at the Carbon Interface (CARBONICE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-06-01
End date: 2023-05-31
Duration (months): 72.0
Total project cost (EUR): 1999806.0
EU funding (EUR): 1999806.0
Participants: 1
Project status: SIGNED

Carbon and water in its various states of matter make up a substantial proportion of our Universe. The two materials are highly dissimilar with respect to their chemical and physical properties. Elemental carbon is even often referred to as a hydrophobic, ‘water-hating’ material. Yet, the two materials often coexist and critical processes take place at the interface between these unlike chemical species. This includes the hydration shells of hydrophobic moieties in biomolecules, clathrate hydrate materials where water molecules crystallise around hydrophobic guest species as well as icy comets which are often black due to the presence of carbon at their surfaces. The aim of the CARBONICE project is to investigate the interface and interplay between water and carbon in detail. Using new and innovative experimental strategies, the water molecule will be placed in a variety of different yet highly relevant carbon environments. This will give us unprecedented insights into how water hydrates hydrophobic species which is highly important in the context of hydrophobic interactions. Investigations into how carbon species influence phase transitions of ice will give new insights into crystallisation phenomena but will also reveal the factors that lead to the formation of either ferro- or antiferroelectric ices. Creating carbon – ice composites in the lab as they exist on comets will enable us to understand the complex weather cycles on comets and may help explaining the unusual surface features recently identified by the Rosetta space probe. In summary, this truly multidisciplinary project opens up a new spyhole to critically important processes at the water – carbon interface. The results will have an impact on the space, atmospheric and general materials sciences but will also be highly relevant with respect to further optimising the computer models of water as well as understanding the properties of water in nano-confinements and how it drives biological processes.

Keywords: clathrate hydrates,carbon materials,amorphous materials,stacking disordered materials,diffraction,calorimetry,spectroscopy
UA NCP FOR DEEPER INTEGRATION OF UKRAINIAN RESEARCHERS TO EURATOM (UAinEuratom)

Framework: Horizon 2020 — Euratom
Programme: Euratom other actions
Action type: Coordination and support actions
Countries involved: Ukraine
Call: Training and information programme following association of Ukraine in Euratom in 2016 (H2020-IBA-EURATOM-Ukraine-2018, 2018)
Start date: 2018-07-01
End date: 2020-09-30
Duration (months): 27.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The Association Agreement between Ukraine and Euratom was signed on 27 June 2016 and entered into force on 28 October 2016. Better integration of Ukrainian nuclear research entities into European nuclear research networks could be seen as mutually beneficial for the whole Euratom research community. “UA NCP for deeper integration of Ukrainian researchers to Euratom” project (Acronym: UAinEuratom) is initiated in order to provide deeper integration and improved participation of Ukrainian researchers and research entities in Euratom research activities with future aim to increase their participation in Euratom projects, thereby enabling a more broad and effective cooperation in the field of research on fission and fusion, and fully exploiting the potential of Ukrainian research entities regarding their infrastructures, capacities and research programmes. NSC KIPT was officially appointed by the Ukrainian authorities as National Contact Point to Euratom in 2017. UAinEuratom is an 18 months project that is initiated as support and coordination action for the NCP to Euratom in Ukraine (UA Euratom NCP) to integrate Ukrainian researchers and research centers to Euratom. UAinEuratom project specific objectives UAinEuratom project has the following specific objectives: • Strengthening of UA scientists participation to Euratom programmes; • Enhancing of Ukrainian - EU networking activities in Euratom research area; • Raising of Euratom programme awareness among representatives of Ukrainian research centers, SMEs, authorities and strengthening the link between Euratom and Ukrainian science communities; There are four work packages that include all project activities to achieve the objectives. All work packages will be managed and implemented by KIPT (Ukraine). • WP1. UA Euratom NCP skills and services improvement, • WP2. Enhancing of UA-EU networking activities in Euratom research area, • WP3. Communication and dissemination, • WP4. Project management.

Keywords: national contact point,euratom,fission research,fusion research
Human Exposomic Determinants of Immune Mediated Diseases (HEDIMED)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Preventing disease
Action type: Research and Innovation actions
Countries involved: Austria,Estonia,Italy,Germany,Finland,Finland,Finland,Sweden,Switzerland,Norway,Finland,Greece,Czechia,United States,Denmark
Call: The Human Exposome Project: a toolbox for assessing and addressing the impact of environment on health (H2020-SC1-2019-Single-Stage-RTD, 2019)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 11992338.74
EU funding (EUR): 11992338.74
Participants: 23
Project status: SIGNED

Immune-mediated diseases (IMDs) are increasing rapidly in the developed countries constituting a huge medical, economic and societal challenge. The reasons to this epidemic are not known, but exposome needs to play an important role since genetic factors cannot explain such a rapid change. In the HEDIMED project altogether 20 academic and industrial partners will join their multidisciplinary and supplementary forces to identify exposomic determinants which are driving this epidemic. The project is based on a combination of data and biological samples from large clinical cohorts constituting the largest clinical resource in this field including 350.000 pregnant women, 28.000 children prospectively followed from birth and 6.600 children from cross-sectional studies. HEDIMED focuses on common chronic IMDs that cause a significant disease burden, including type 1 diabetes, celiac disease, allergies and asthma. Exposomic disease determinants and the underlying biological pathways will be identified by exploratory approach using advanced omics and multiplex technologies combined with cutting–edge datamining technologies. Particular emphasis is paid on early fetal and childhood exposome since the disease process is known to start early. Inclusion of several IMDs makes it possible to identify determinants that are common for many IMDs facilitating the development of widely operating treatments. HEDIMED includes also data and samples from clinical trials that have used exposomice interventions and cell and organ culture models to help the identification of causal associations. HEDIMED will generate an open-access toolbox that offers various kind of data, new technologies, interactions forums, latest information and functional tools for several stakeholders to facilitate the efforts to find ways to control the IMD epidemic. HEDIMED will generate several innovations which can become exploited widely in diagnostic, therapeutic, preventive and health-economical applications. HEDIMED will work together with the other projects (EXPANSE, HEAP, ATHLETE, EQUAL-LIFE, LONGITOOLS, EPHOR, REMEDIA and EXIMIOUS) funded within the Human Exposome programme call H2020 SC1-BHC-2018-2020, in order to achieve collaboration and synergy

Keywords: exposome,immune mediated diseases,microbes,toxicants,diet,omics,sensoring,data mining,simulation models,prevention trials,birth cohorts,type 1 diabetes,celiac disease,allergy,asthma
PancREatic Cancer OrganoiDs rEsearch Network (PRECODE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Germany,Spain,Ireland,Italy,Germany,Poland,Sweden,Sweden,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2019, 2019)
Start date: 2019-10-01
End date: 2024-03-31
Duration (months): 54.0
Total project cost (EUR): 3992891.76
EU funding (EUR): 3992891.7600000002
Participants: 15
Project status: SIGNED

The PRECODE Network (PancREatic Cancer OrganoiDs rEsearch) central mission is to establish pancreatic organoid research firmly in the European Union, by training the next generation of creative and innovative researchers in pancreatic cancer. This will be done through a shared doctorate program of excellence that fulfils the three “I”: international, interdisciplinary and intersectorial. Organoids can be viewed as small micro-organs which can recapitulate the organization and the function thereof. As micro-organs organoids can be used to reduce animal experiments and help to reach 3R goals. Organoids from pancreatic cancer will help us to learn which drugs might help in the therapy of this terrible disease. They can be isolated from a variety of clinical sources with minimal material needed. This makes them a perfect tool for precision medicine. Sequencing, metabolomics and high throughput in vitro experiments to deduct the best possible drug combination fit hand in glove with this approach. Training of ESRs will be achieved by e-learning, workshops and secondments. They will earn to cultivate and manipulate organoids as well as cutting edge molecular biology techniques. Therefore our work group consists of 15 beneficiaries and 7 partner organization (including three patient advocate groups from Sweden, Italy and Germany) to develop those technologies and to train ESRs in their application. PRECODE will therefore connect the concepts of investigation, education and innovation establishing a capacitation for the ESRs that goes beyond the state of the art and that will allow them to improve their competences and their professional career at the same time that we advance towards innovation in the field of pancreatic cancer research.

Keywords: organoid,drug response,high throughput screening,next generation sequencing,metabolomics
Foundations of Efficient Lattice Cryptography (FELICITY)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: France
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-10-01
End date: 2020-09-30
Duration (months): 60.0
Total project cost (EUR): 1311687.5
EU funding (EUR): 1311687.5
Participants: 1
Project status: CLOSED

Public key cryptography is the backbone of internet security. Yet it is very likely that within the next few decades some government or corporate entity will succeed in building a general-purpose quantum computer that is capable of breaking all of today's public key protocols. Lattice cryptography, which appears to be resilient to quantum attacks, is currently viewed as the most promising candidate to take over as the basis for cryptography in the future. Recent theoretical breakthroughs have additionally shown that lattice cryptography may even allow for constructions of primitives with novel capabilities. But even though the progress in this latter area has been considerable, the resulting schemes are still extremely impractical. The central objective of the FELICITY project is to substantially expand the boundaries of efficient lattice-based cryptography. This includes improving on the most crucial cryptographic protocols, some of which are already considered practical, as well as pushing towards efficiency in areas that currently seem out of reach. The methodology that we propose to use differs from the bulk of the research being done today. Rather than directly working on advanced primitives in which practical considerations are ignored, the focus of the project will be on finding novel ways in which to break the most fundamental barriers that are standing in the way of practicality. For this, I believe it is productive to concentrate on building schemes that stand at the frontier of what is considered efficient -- because it is there that the most critical barriers are most apparent. And since cryptographic techniques usually propagate themselves from simple to advanced primitives, improved solutions for the fundamental ones will eventually serve as building blocks for practical constructions of schemes having advanced capabilities.

Keywords: post quantum cryptography,lattice cryptography
A Truly Disruptive Entertainment and Educational Digital Application for Primary School Aged Children (azoomee)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: United Kingdom
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-08-01
End date: 2016-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Although the internet was designed for adults, children, from as early ages as three years, are increasingly becoming active on it. Over 87% of children aged between 5 and 8 years use the internet for gaming, video series, education and entertainment. Many have been accidentally exposed to inappropriate content such as pornography, animal cruelty, and eating disorder websites. 40% of children have reported encountering risks online including cyber-bullying, exposure to content promoting anorexia or self-harm or misuse of their personal data. While parents are deeply concerned about these risks, they currently have no way of tracking what children watch online and even if they could, that would be cumbersome to many who are hard pressed for time. Available children’s sites partially meet the need, none offer an integrated solution combining age-appropriate educational and entertainment content with in-built parental controls and social media tools adapted for primary aged school children. Azoomee is an integrated online solution that offers a safe, stimulating, entertaining and educational online experience for primary school aged children. In addition to providing videos, games and educational tools, it aims to prepare young children for the risks of the digital world and to influence their development, both on and offline. The basic architecture has been built and a minimally viable product (available on iOS and Android) is growing exponentially in user base. What is left is to develop a white-listed browser, enhance video streaming functionality, enhance personalisation features and secure more premium content. Having completed extensive research studies in the UK, in the Feasibility Study we will conduct similar studies in France, Germany, Spain, Belgium and the Netherlands and search for partners and content providers for effective and widespread distribution, dissemination and promotion of Azoomee

Keywords: technology commercialisation,technology development,children,online,secure,educational
Planetary Mapping (PLANMAP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Italy,Italy,France,United Kingdom
Call: Scientific data exploitation (H2020-COMPET-2017, 2017)
Start date: 2018-03-01
End date: 2021-02-28
Duration (months): 36.0
Total project cost (EUR): 1499620.0
EU funding (EUR): 1499620.0
Participants: 6
Project status: CLOSED

We are living in a golden age for space exploration and the world-wide interest in planetary surface exploration, with particular regard to future robotic and human missions, is rapidly increasing. Many nations can maintain robust space programs that continuously provide a great amount of highly complex datasets. Geological maps provide the context for all observations and interpretations of surface and subsurface processes on any planetary body and their histories. Nonetheless, planetary geological maps are still developed almost exclusively by a single research institute in the world (USGS-USA), resulting in exceedingly long publication delays among other grave disadvantages. Thus, it is high time to improve this situation in order to maximize the scientific output of planetary missions and improve the position of Europe in this context. PLANetary MAPping project (PLANMAP) aims at providing highly informative geological maps of the three main bodies of interest for European space missions in the next decade: Mars, Mercury and the Moon. These maps will include spectral information, elemental composition, absolute ages and ground truth information. They will also provide the basis for subsurface 3D geological modelling, and will be disseminated using dedicated web-GIS software.

Keywords: space international cooperation,planetary mapping,planetary geology,3d geological modeling,virtual environments
Mechanical and systemic control of growth during Drosophila abdominal development (GrowthControl)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Control of tissue size during animal development is of crucial importance to achieve the correct body/organ size and shape, and it underpins the evolution of animal size and architecture. How is tissue size tightly controlled during development? How is each cell in a developing animal instructed to stop growing and dividing when the correct body size and shape has been reached? Answers to these questions are of fundamental importance to our understanding of diseases such as cancer as well as for regenerative medicine. Using the development of the Drosophila abdominal epidermis as a model, we will perform long-term quantitative in vivo analysis of cellular behaviours and generate fluorescent live reporters of growth-promoting pathways to correlate activity patterns with developmentally regulated growth phases. We will manipulate tissue mechanics as well as nutrient-sensing pathways to understand how nutrient availability and tissue-intrinsic physical properties are integrated to specify final tissue size. In combination with computational modelling, we aim to generate a better understanding of developmental growth, as well as the mechanisms that trigger tissue growth arrest. The mechanisms regulating how cell proliferation is triggered in response to extrinsic and intrinsic stimuli and the transitions between different proliferative/growth states, particularly in tumour cells or regenerative tissues, are poorly understood. As these events are precisely defined in Drosophila abdominal morphogenesis, we hope to uncover the internal logic modulating cell cycle/growth rates transitions that can be used as a genetically tractable paradigm for the study of equivalent processes in cancer, regeneration or development.

Keywords: tissue growth,development,tissue mechanics,growth arrest,abdominal morphogenesis
Thermochemical fluids in greenhouse farming (TheGreefa)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Innovation actions
Countries involved: Germany,Germany,Spain,Spain,Italy,Italy,Switzerland,Tunisia,Poland,France
Call: Defossilising agriculture – solutions and pathways for fossil-energy-free farming (H2020-FNR-2020-1, 2020)
Start date: 2020-10-01
End date: 2024-05-31
Duration (months): 44.0
Total project cost (EUR): 4651865.0
EU funding (EUR): 4029238.13
Participants: 12
Project status: SIGNED

This project is aimed at a new technology for heating, cooling, air humidity control and water recovery in greenhouses as well as for drying of agricultural goods using thermo-chemical conversion principles based on the use of salt solutions (thermochemical fluids). The common effect in all applications is the hygroscopic property of thermochemical fluids, allowing an uptake of water vapor from air thus releasing sensible heat involved in the phase change. The technology allows to (1) use unexplored potentials of solar- and residual heat at farm level, (2) to convert and to store the heat into thermochemical potential without thermal losses and (3) to use the potential through re-conversion of the potential into heat within the above-mentioned applications. Within two different demonstrators in Central European Climate (heating) and Mediterranean Climate (cooling, water recovery and desalination) the technology will be tested, further developed and disseminated. Lab tests will explore the processes and materials involved, will include tests on material drying and on interactions between different applications. Development of improved knowledge on modelling of the involved processes, the simulation and control of specific applications and the development of control strategies are further tasks to provide a bright insight into the novel approach. Strategies to bring the technology to market will be developed. Thermochemical applications in agriculture have the potential to significantly reduce the energy consumption in greenhouse climate control as well as in crop drying and will provide an alternative to energy intensive water desalination in arid regions. The uptake, conversion and storage of solar heat from greenhouses even provides the perspective to turn protected intensive horticulture from an energy/water consuming to an energy/water producing method, allowing to secure the important market of food production and food processing and to extend it to new regions.

Keywords: sustainable greenhouse farming,temperature and humidity control,water recovery,absorption,desiccants,thermochemical fluid,renewable energy,long term storage