Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Pediatric Hospitals as European drivers for multi-party computation and synthetic data generation capabilities across clinical specialties and data types (PHEMS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Maintaining an innovative, sustainable and globally competitive health industry
Action type: Research and Innovation actions
Countries involved: Finland,Netherlands,Italy,Spain,United Kingdom,Latvia
Call: Scaling up multi-party computation, data anonymisation techniques, and synthetic data generation (HORIZON-HLTH-2022-IND-13, 2022)
Start date: 2023-10-01
End date: 2026-09-30
Duration (months): 36.0
Total project cost (EUR): 5535951.25
EU funding (EUR): 5535951.25
Participants: 13
Project status: SIGNED

Cross-border collaboration can tackle the challenges in accessing relevant health data essential for international collaboration between scientists and clinicians, researchers, and health industry. Privacy concerns and regulations on personal data have made the sharing of health data increasingly complex and time-consuming for data controllers, thus severely limiting the access of SMEs, researchers, and innovators to health data. Further complications in cross-border collaboration arise from differences in interpreting the EU GDPR, national regulations, and heterogenous and changing data permit processes at hospital sites. The PHEMS project will provide European children’s hospitals with a decentralized and open health data ecosystem concept consisting of technical components and governance frameworks. The objective is to facilitate access to health data, advance federated health data analysis and build services for the on-demand generation of shareable, synthetized, and anonymized datasets. To achieve this, the project will focus on bridging the gaps in data access and use, especially in the integration of ethical, legal, and technical requirements, including the responsibilities of data controllers and the rights of data subjects. This will allow health data controllers to engage in collaboration without losing control on compliance with respect to GDPR, national legislation or internal policies of their organization. The techniques and tools for generating algorithmically anonymized and synthetic datasets will undergo robust validation processes through three clinical use cases conducted by the European Children’s Hospitals Organisation (ECHO) community. The goal is to assess the usage of custom-generated synthetic data with real-life questions. Data users, such as researchers, SMEs, innovators and the pharmaceutical and MedTech industry, will be engaged through community building, hackathons, and interaction with relevant European large-scale initiatives.

Keywords: synthetic data,data anonymization,federated analytics,omop cdm,data access governance,pediatrics,trust framework
Superior boron carrier for Boron Neutron Capture Therapy (BNCT): Game changer in cancer care (TB0010)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Finland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Tenboron is a clinical stage, revolutionary cancer treatment company, based in Finland, with curative intent for solid tumours, specifically head-and-neck cancer (HNC). In the current scenario, HNC patients, especially those with a recurrent disease (rHNC), do not have satisfying treatment options. The preferred approach is surgery, which has severe side effects like disfigurement, and it is rarely an option for rHNC patients. Tenboron developed and patented TB0010, a boron (10B) -carrier that will revolutionize the field of Boron Neutron Capture Therapy (BNCT). BNCT is a low energy irradiation technique that has been shown to be beneficial in the treatment of advanced stage HNC, however the sub-optimal nature of the 10B-carrier available has hindered its use in the clinic. TB0010 is safe and efficient in destroying cancer cells without affecting healthy tissue, as it has been demonstrated by pre-clinical data and suggested by the promising results of the ongoing FIH. We need €10.5M to carry out phase 2 clinical trials in order to reach the market. We are seeking the EIC accelerator fund to complete the clinical validation, thereby de-risking our project and attracting private investors. Once we receive the regulatory approval from EMA, we will commercialize our solution in Europe and beyond. The revenues generated will be invested in the development of additional 10B-carriers targeting other kinds of tumours. We are a strong and motivated team with over 70 years of combined experience in the field of oncology, radiotherapy, medical research, clinical trials, project management, and quality assurance as well as relevant commercial expertise. We also count on a solid network of clinicians, researchers and medical physicists including top academic researchers.

Keywords: boron carrier,boron neutron capture therapy,head and neck cancer,targeted radiation therapy,clinical trial,low toxicity neutron radiation,cmc process
The world’s first Eco-friendly and Cost-effective active Anode material ready to be mass produced in eXisting industrial facilities (ECo-AnodeX)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Netherlands
Call: Renewable energy sources and their whole value chain including materials development and recycling of components (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 3570875.0
EU funding (EUR): 2499612.5
Participants: 1
Project status: SIGNED

CarbonX is a fast growing startup focused on the development of an innovative eco-friendly and cost-effective anode active material, which is ready for mass production in existing industrial facilities. Founded in 2014 at TU Delft, CarbonX has raised €17 million, developing a patented, high-performance, and sustainable alternative to graphite for Electric Vehicle (EV) batteries. CarbonX® features a unique 3D crystalline network with improved electron conductivity and ion transfer, offering superior battery performance than existing graphite-based anodes. The company has validated scaling potential by producing CarbonX® at existing carbon black facilities, demonstrating a production capacity of over 20,000 tons annually. The EV market's increasing demand for graphite and Europe's dependency on imports, mainly from China, highlight the critical need for local, sustainable alternatives. CarbonX addresses these challenges with a low-temperature, continuous production process that significantly reduces CO2 emissions. The company's commercial strategy involves selling CarbonX® at €5-€6 per kg through partnerships with carbon black manufacturers, cell manufacturers, and EV OEMs, targeting Europe, the US, China, India, and South Korea. By 2030, the global market for carbon materials for batteries is projected to reach €16.8 billion. CarbonX aims to capture a €600 million market share, leveraging its sustainability, cost-effectiveness, and scalability. The project supports the EU's climate goals, contributing to reducing CO2 emissions by up to 10 Gton by 2050. CarbonX plans to create over 200 direct jobs and 350 indirect jobs by 2030. The ECo-AnodeX project positions CarbonX as a key player in the global transition to electric mobility and renewable energy, addressing critical supply chain and environmental challenges.

Keywords: sustainable anode materials,ev batteries,nanocarbon materials,mass scale production,critical raw material substitution
Reinventing light freight transportation for a low-carbon future (GreenCourier)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2315204.0
EU funding (EUR): 2315204.0
Participants: 1
Project status: SIGNED

MCLedger addresses the inefficiency and environmental impact of overland freight transport, particularly the reliance on road transport to deliver express freight, such as small packages commonly associated with e-commerce. 72% of e-commerce delivery is made by road, and this market is growing at a CAGR of 22.3%, estimated at 18 bn deliveries per year in Europe by 2023, with an average of 6 purchases per buyer. This translates into a real emergency related to significant CO2 emissions because resources could be used more efficiently, especially given the capacity available on electric rail networks. GreenCourier facilitates a more sustainable, efficient, and cost-effective transport option that benefits all stakeholders from an operational, environmental, and economic perspective. Although multimodality is well-known in large-distance logistics, it does not exist in shot- and medium-range transport. MCLedger will open a new market by offering the first multimodal option competitive with road transport in terms of cost and speed but with a fraction of the environmental footprint. It also provides logistical advantages, such as bypassing road traffic congestion and utilising the predictability of passenger train schedules, leading to more reliable delivery times. Regarding the innovative elements of the solution, the digital component is strategic. Still, the adaptation of rail operating processes and the hardware layout of trains and stations are key elements of the solution. The solution includes SW developments to manage the end-to-end delivery service (a mobile app, a cloud-based platform for scheduling, orchestrating, and managing operations, a web-based front-end for service managers, a track-and-trace service based on NFC and blockchain, and a module for service design) and hardware components to allocate space in trains – similar to the lockers used for e-commerce in some buildings and public places – which are co-managed by MCLedger and the rail operator.
Mapping metabolic responses to understand coexistence and community functioning (META_FUN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Environmental B iology, Ecology  and E volution
Panel description: For all organisms : Ecology, biodiversity, environmental change , evolutionary biology, behavioural ecology, microbial ecology , marine biology, ecophysiology, theoretical developments and mod elling
Countries involved: Portugal
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-05-01
End date: 2029-04-30
Duration (months): 60.0
Total project cost (EUR): 1488550.0
EU funding (EUR): 1488550.0
Participants: 2
Project status: SIGNED

The metabolism of organisms affects the productivity of populations and communities. However, the relationship between organismal metabolism and species interactions has been scarcely explored. Hence, predicting the rates at which entire communities flux energy and resources remains difficult. My work shows that the metabolism of organisms measured in isolation does not reflect their performance in communities because species interactions alter how organisms uptake and expend resources. Understanding how such interactions affect metabolism is essential to estimate productivity and how it will change with biodiversity loss and global warming. I propose to use marine phytoplankton as a model laboratory system to determine how metabolic responses to competitors affect coexistence and community functioning. My goal is to connect metabolic theory, that studies physical constraints on the metabolism of organisms in isolation, with community ecology, that centres on species interactions and emergent community properties. Based on my preliminary data, I will map metabolic responses between species that compete for similar resources and test whether these responses stabilise coexistence. I will leverage developments in transcriptomics of non-model organisms to identify the metabolic pathways that underpin metabolic responses. From this basis, I will extend my analysis on larger temporal and biological scales – I will determine how warming modifies metabolic responses and community productivity and, finally, how metabolism evolves in communities. Altogether, this project will demonstrate how metabolic adjustments influence the diversity and functioning of communities. I will use a system that is ecologically important because phytoplankton support 50% of global oxygen production. These results will have broad implications for our understanding of biological systems because the metabolic impact of species interactions shapes the physiology and evolution of all organisms.

Keywords: community ecology,phytoplankton,metabolism,energy flux,competition,chemical cues,warming
Twinning on Functional Antimicrobial Surfaces Testing and Evaluation for Real-world Performance and Sustainability (FAST-Real)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Panel: Life Sciences
Countries involved: Estonia,Germany,Finland,Switzerland
Call: Twinning Bottom-Up (HORIZON-WIDERA-2023-ACCESS-02, 2023)
Start date: 2024-09-01
End date: 2027-08-31
Duration (months): 36.0
Total project cost (EUR): 1499945.83
EU funding (EUR): 1499945.83
Participants: 4
Project status: SIGNED

University of Tartu is the top research university in Estonia and the Baltic States. The objective of FAST-Real (Twinning on Functional Antimicrobial Surfaces Testing and Evaluation for Real-world Performance and Sustainability) project is to strengthen University of Tartu´s research excellence in the field of antimicrobial surfaces design, development and testing, to educate a community of skilled and motivated researchers in the field, increasing the academic skills, proposal preparation and management competence as well as proficiency in innovation transfer. FAST-Real project will focus on knowledge transfer around three important topics related to antimicrobial surface coatings: i) the development of visible light activated coatings, ii) their efficacy assessment in real-life like conditions and iii) ensuring that their use is not inducing antimicrobial resistance development. The advanced partners in FAST-Real project are chosen to fill these three important knowledge gaps and to generate respective synergy. University of Oulu laboratory of Dr Wei Cao has long-standing experiences with photocatalytic materials, including materials activated by visible light. The group of Dr QunRen at Swiss Federal Laboratories for Materials Science and Technology has a long-standing background relevant for real-life like efficacy testing of antimicrobial materials and surfaces. The group of Dr. Frank Schreiber at Bundesanstalt für Materialforschung und -prüfung has focused on antimicrobial resistance evolution in response to bacterial exposure to biocidal compounds over many years. Besides the research-orientated endeavours, the advanced partners will also provide guidance to UTARTU on research networking and project proposal writing, research management, innovation transfer, strengthening co-operation between different institutes within UTARTU, and tackling gender and diversity issues.

Keywords: visible light activated antimicrobial materials,antimicrobial surfaces,real life relevant efficacy testing
The Soviet Union and Israel in the Global Cold War: Antisemitism, Anti-Zionism, and the Ideology of Soviet Foreign Policy (1967-1991) (SOVILASAZION)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 1
Project status: SIGNED

SOVILASAZION is an interdisciplinary historical project dedicated to studying Soviet anti-Zionism as an element of Soviet foreign policy’s ideology. Using previously unavailable recently declassified archival sources, the project will be set out to analyze the interconnections of Soviet anti-Zionism with the practices of Soviet foreign policymaking in the circumstances of the Global Cold War and will discuss them in relation to the domestic antisemitic discriminatory practices in the USSR. By doing so, SOVILASAZION will broaden our understanding of the ideological legacy left from the Cold War era for our times, when the discussion about the difference between antisemitism and the permitted criticism of Zionism is even hotter than 40-60 years ago. Addressing Soviet anti-Zionism as an element of Soviet foreign policy’s ideology, SOVILASAZION will investigate the history of the post-1967 relations between the USSR and Israel. It will address the attempts of the more pragmatically oriented wing of Soviet bureaucracy to lobby the restoration of the official diplomatic relations that had been broken off after the 1967 Six-Day War and study how the ideological limitations prevented such restoration. SOVILASAZION will also address the functioning of the Soviet bureaucracy in the sphere of foreign policy, it will highlight the heterogeneity of Soviet bureaucratic apparatus and, overall, will broaden our understanding of this underresearched part of the Cold War history.

Keywords: soviet union ideology cold war antisemitism anti zionism israel foreign policy
Galactic ArchaeoLoGy based on K-band and Optical Spectroscopy (GALYKOS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-01-09
End date: 2025-01-08
Duration (months): 24.0
Total project cost (EUR): 199440.96
EU funding (EUR): 199440.96
Participants: 1
Project status: CLOSED

The standard paradigm of the build-up of spiral galaxies recognises a two-phase scenario that comprises a quasi-monolithic formation of the bulge early-on, followed by the gradual assembly of the disk. However, recent observational evidence strongly suggests joint formation and perpetual co-evolution of both structures. Elucidating this process in its full complexity is of key astrophysical relevance and only possible through accurate characterisation of the main stellar components (bulge, disk and bar). These are primarily studied via photometric decomposition techniques, conventionally by extrapolating the exponential profile of the disk up to the galactic centre. Though hardly ever questioned, this is a strong assumption with broad and far-reaching implications, which could effectively be violated, particularly if the disk evolves in tandem with the bulge. Our latest work, Breda et al. (2020b), provided, for the first time, indirect observational evidence for a central down-bending of the disk, reinforcing theoretical predictions. This project, GALYKOS, will pioneer an unprecedented exploration of the central region of spiral galaxies through the combination of two techniques, i.e., spatially resolved spectral synthesis and kinematical Schwarzschild orbital decomposition of optical and K-band integral field spectroscopy data. This innovative methodology will permit to quantitatively constrain the true structure of the disk within the galactic centre and explore its dependence on the physical properties of spirals, revolutionizing photometric decomposition studies. Apart from opening new routes for the exploration of the assembly history of galaxies, this action will prompt for conceptual changes in our understanding of galaxy formation and evolution. Finally, it will rectify well-established galaxy scaling relations such as super-massive black hole vs. bulge and yield crucial insight into the nature of bulgeless galaxies, a remaining challenge for the ΛCDM model.

Keywords: galaxy structure galaxy dynamics integral field spectroscopy spectral synthesis galactic archaeology
Conference on the European Innovation Agenda (NEXEIA)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: other EIC
Destination: Other destinations
Action type: Coordination and support actions
Countries involved: Spain
Call: Spanish presidency innovators summit (HORIZON-EIC-2023-SPAIN-IBA-01, 2023)
Start date: 2023-07-11
End date: 2024-04-10
Duration (months): 9.0
Total project cost (EUR): 328460.0
EU funding (EUR): 300000.0
Participants: 1
Project status: CLOSED

This high-level conference will gather public and private representatives from the national, European and international innovation ecosystem to discuss how to Improve Policy Making Tools in line with the 5th flagship of the New European Innovation Agenda. The conference will help to amplify political messages on the need for sustained investment in core capabilities to turn scientific knowledge into business, based on examples of European partners.

Keywords: innovation,deep tech,start up