Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
FROM PATIENT DATA TO PERSONALISED HEALTHCARE IN ALZHEIMER’S DISEASE (PREDICTAD)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Towards sustainable and personalised healthcare
Action type: Collaborative project
Countries involved: Finland,United Kingdom,United Kingdom,Sweden,Italy,Denmark,Sweden
Call:  (FP7-ICT-2007-2, 2007)
Start date: 2008-06-01
End date: 2011-11-30
Duration (months): 42.0
Total project cost (EUR): 3908233.0
EU funding (EUR): 2891526.0
Participants: 10
Project status: CLOSED

Dementia causes long and oppressive suffering to patients and their relatives and imposes enormous costs on society. About 25 million people suffered from dementia in 2000. As a 4-fold increase of this number is expected by 2050, dementia is one main health issue of the next decades. Alzheimer’s disease (AD) covers 60-70% of all dementia cases. No cure for AD exists, and effective and reliable early diagnostic techniques are lacking. Early diagnosis and progress monitoring of AD is a central part of treatment once future drugs and prevention strategies become available. There is a strong indication that different biomarkers provide a reliable and early indication of AD prior to its major clinical signs. However, optimal early diagnosis requires information from a combination of different biomarkers to be used in a clinically useful way. The objective of PredictAD is 1) to find the best combination of biomarkers for AD diagnostics from heterogeneous data (imaging, electrophysiology, molecular level, clinical tests, demographics) and 2) to develop clinically useful tools integrating the optimal biomarker results. Comprehensive biomarker discovery techniques and rigorous statistical models will be developed using the consortium’s large databases. The accuracy and usability of models and tool will be clinically evaluated. The cost-effectiveness of heterogeneous data in AD diagnostic procedures will be studied. By reaching its objectives, PredictAD provides an efficient and reliable solution for early AD diagnosis in clinical practice. The impacts on patients, their relatives and society are reduced suffering and costs. As we are living in the dawn of an era of new drugs and prevention strategies combined with increasing AD prevalence, now is the time to exploit the vast potential of information hiding in heterogeneous patient databases. PredictAD combines the best forces in Europe to solve the AD diagnostics problem, and hence strengthens EU leadership on the market.

Keywords: alzheimer's disease,early diagnosis,personalized healthcare,statistical modeling,multimodal data
Open Accessibility Everywhere: Groundwork, Infrastructure, Standards (AEGIS)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: ICT for Independent Living, Inclusion and Governance
Action type: Collaborative project
Countries involved: Spain,United Kingdom,Belgium,Germany,United Kingdom,Greece,Czechia,Romania,Sweden,Canada,United Kingdom,United Kingdom,Belgium,Switzerland,Sweden
Call:  (FP7-ICT-2007-2, 2007)
Start date: 2008-09-01
End date: 2012-08-31
Duration (months): 48.0
Total project cost (EUR): 12582314.0
EU funding (EUR): 8062709.0
Participants: 24
Project status: CLOSED

The ÆGIS project seeks to determine whether 3rd generation access techniques will provide a more accessible, more exploitable and deeply embeddable approach in mainstream ICT (desktop, rich Internet and mobile applications). We develop and explore this approach with the Open Accessibility Framework (OAF) through which we address aspects of the design, development and deployment of accessible mainstream ICT. The OAF provides embedded and built-in accessibility solutions, as well as toolkits for developers, for “engraving” accessibility in existing and emerging mass-market ICT-based products, thus making accessibility open, plug &amp; play, personalised &amp; configurable, realistic &amp; applicable in various contexts; ÆGIS is placing users and their needs at the centre of all ICT developments. Based on a holistic UCD, AEGIS identifies user needs and interaction models for several user groups, (users with visual, hearing, motion, speech and cognitive impairments as well as application developers) and develops open source-based generalised accessibility support into mainstream ICT devices/applications: A) desktop, B) W3C/WAI standards-abiding accessible rich web applications and C) embedded generalized accessibility in terms of user interfaces and applications running into standard (CDLC and CDC) as well as rich features cell phones and PDAs. All developments are iteratively tested with hundreds of end users, developers and experts in three phases and 4 Pilot sites Europewide (in Belgium, Spain, Sweden and UK). The project includes strong industrial and end users participation (the participating Industries are among the market leaders in the corresponding mainstream ICT markets). The project results’ uptake is promoted by strong standardization activities, as well as an Open Accessibility Everywhere Group (OAEG) that will live beyond the project lifetime, bringing together end users and developers in a “stars rating” system assessing accessibility and usability of mai

Keywords: third generation accessibility,mainstream-ict embedded accessibility,desktop,rich internet,mobile devices
Optically Driven Terahertz Amplifiers (OPTHER)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: Italy,France,Denmark,France,France,Germany
Call:  (FP7-ICT-2007-2, 2007)
Start date: 2008-04-01
End date: 2011-09-30
Duration (months): 42.0
Total project cost (EUR): 4101298.0
EU funding (EUR): 2449847.0
Participants: 7
Project status: CLOSED

This proposal focuses on the development of an application-specific component that works in the Terahertz (THz) regime; in this context, we propose to realize a THz source with innovative features specific for monitoring systems for safety and security. Until now the use of THz monitoring system has been strongly limited due to the very low power and the large dimensions of the existing sources in the THz.The OPTHER project aims at solving this limitation with a breakthrough with respect to all the other solutions up to know available in Europe, U.S. and Asia. We plan to use available optical THz sources (such as Quantum Cascade Lasers (QCL) or photomixing systems) and boost their performances by designing and fabricating compact, efficient and reliable novel vacuum THz amplifier. The breakthrough of this proposal is the enhancement of the performance of THz optical source by using vacuum THz amplifiers purposely designed and integrated with the optical driver. The novel THz amplifier will be based on field emitting carbon nanotubes (CNT) used as cold cathodes. Two alternative schemes will be employed for amplification. - In the first one (THz drive signal amplifier) the continuous wave electron beam emitted by the CNT cathode is modulated by the electric field in the interaction structure driven by a THz signal - In the second one (optically modulated beam THz amplifier) the emission of current is driven by the THz signal. With this second scheme the delivery of high power output should be facilitated. The source output signal will be fully characterized using commercial broadband detectors such as Schottky diodes or bolometers. The composition of the consortium has been carefully arranged for including all the expertise necessary for a successful conclusion of the research activity. In fact, the present consortium is composed by 6 partners, with complementary research expertise and background: two universities, a research institute and three industries

Keywords: thz sources,optical system,qcls,photomixers,cold cathodes,carbon nanotubes
Terabit-on-chip: micro and nano-scale silicon photonic integrated components and sub-systems enabling Tb/s-capacity, scalable and fully integrated photonic routers (BOOM)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: Greece,Germany,Belgium,Germany,Germany,Netherlands,Germany,Italy,Netherlands
Call:  (FP7-ICT-2007-2, 2007)
Start date: 2008-05-01
End date: 2011-09-30
Duration (months): 41.0
Total project cost (EUR): 4235362.0
EU funding (EUR): 3100000.0
Participants: 10
Project status: CLOSED

BOOM is an integration project that aims to pursue the systematic advancement of Silicon-on-Insulator (SOI) integration technology to develop compact, cost-effective and power efficient silicon photonic components that enable photonic Tb/s capacity systems for current and new generation high speed broadband core networks. BOOM develops fabrication techniques as well as flip-chip bonding and wafer-scale integration methods to fabricate and mount the complete family of III-V components on SOI boards including: arrays of Semiconductor Optical Amplifiers, monolithic blocks of Electro-absorption modulated lasers (EMLs) and highly efficient photodetectors. As such the BOOM SOI optical board technology will be able to blend the cost-effectiveness and integration potential of silicon with the high bandwidth and processing power of III-V material and provide a new generation of functional and miniaturized photonic components including: (a) a single 160 Gb/s SOI Wavelength Converter (WC) and a quadruple array of 160 Gb/s WCs with a record chip throughput of 640 Gb/s on a size 20x5 mm2 , (b) a compact, eight channel, ultra dense WDM InAlAs-InGaAs photoreceiver with record high responsivity and (c) a dual SOI EML transmitter together with its electronic drivers on a single chip. In addition, BOOM invests in the development of improved CMOS compatible waveguide technologies to fabricate miniaturized, low loss and fully reconfigurable wavelength routing cross-connects based on two dimensional grids of serially interconnected micro-ring resonators. BOOM will perform system level integration of all these components to assemble the first prototype rack-mount, ultra-high capacity routing platform based on silicon photonics that will require minimum board space and power consumption and achieve a total throughput of 640 Gb/s. The platform will be evaluated in a network operator test bed employing GbE optical signals.

Keywords: silicon photonics,silicon-on-insulator,micro-ring resonators,flip-chip bonding,wafer-scale integration,cmos compatible waveguide technology,optoelectronic convergence,terabit capacity photonic
Patient specific image-based computational modelling for improvement of short- and long-term outcome of vascular access in patient on hemodialysis therapy (ARCH)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Towards sustainable and personalised healthcare
Action type: Collaborative project
Countries involved: Italy,Netherlands,Belgium,Slovenia,United Kingdom,Netherlands
Call:  (FP7-ICT-2007-2, 2007)
Start date: 2008-06-01
End date: 2011-11-30
Duration (months): 42.0
Total project cost (EUR): 5716740.0
EU funding (EUR): 3759499.0
Participants: 8
Project status: CLOSED

More than half a million people live in Europe on chronic renal replacement therapy by hemodialysis (HD). This number increases annually at a constant rate of 8%. The Achilles heel of HD is the vascular access (VA) used to connect patient circulation to the artificial kidney. The current recommendation for VA is the native arteriovenous fistula (AVF), surgically created in the forearm. VA dysfunction is the major cause of morbidity and hospitalisation in HD patients, and the major limitation of HD treatment. Short- and long-term AVF dysfunction includes non-maturation (inadequate increase in blood flow after surgery), stenosis due to intimal hyperplasia, and ultimately thrombotic occlusion. Steal syndrome and cardiac failure are also common complications of AVF creation. Prediction and prevention of VA dysfunction are still open clinical challenges with more than 90,000 procedures/year in Europe for revision or reoperation. Despite the magnitude of the clinical problem, there has been a paucity of novel therapeutic interventions in this field due to complex mechanisms responsible for AVF complications, which are closely related to both the sudden and sustained hemodynamic changes involved in AVF creation. The ARCH project will develop image-based patient-specific computational modelling tools to simulate hemodynamic changes induced by AVF surgery and long-term vascular and cardiac adaptation. The modelling tools will be designed and experimentally validated to predict AVF function for improvement of surgical planning and AVF management, and will be provided to clinical end users by a distributed IT infrastructure. Verification of model prediction of AVF maturation, patency, onset of steal syndrome and cardiac overload will be performed on the basis of prospective observational studies in HD patients. The basic tools and data produced in the context of the project will be made available under open-source licenses and shared in the context of the VPH initiative.

Keywords: vascular access,hemodialysis,medical imaging,image processing,hemodynamics,patient-specific computational modelling,surgical planning.
Integrated Platform for Autonomic Computing (IPAC)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: Greece,Switzerland,Italy,Cyprus
Call:  (FP7-ICT-2007-2, 2007)
Start date: 2008-05-01
End date: 2011-02-28
Duration (months): 34.0
Total project cost (EUR): 2496619.0
EU funding (EUR): 1650000.0
Participants: 6
Project status: CLOSED

The IPAC (Integrated Platform for Autonomic Computing) proposal aims at delivering a middleware and service creation environment for developing embedded, intelligent, collaborative, context-aware services in mobile nodes. IPAC relies on short range communications for the ad hoc realization of dialogs among collaborating nodes. Advanced sensing components leverage the context-awareness attributes of IPAC, thus rendering it capable of delivering highly innovative applications for mobile and pervasive computing. IPAC networking capabilities are based on rumour spreading techniques, a stateless and resilient approach, and information dissemination among embedded nodes. Spreading of information is subject to certain rules (e.g., space, time, price). IPAC nodes may receive, store, assess and possibly relay the incoming content to other nodes. The same distribution channel is followed for the dissemination of new applications and application components that “join the IPAC world”. IPAC aims at providing all the communication functionality, relying on flexible components: the Sensing Elements Component, the Short Range Communication Component, and the IPAC core middleware itself. An important feature of IPAC is the embedded intelligence which relies on emerging knowledge representation and reasoning schemes, allowing behaviour self-adjustment, seamless interoperation at the messaging level and software integration. An Application Creation Component will also be designed, implemented and tested. This component refers to all tools, APIs and libraries, which assist the rapid application development for IPAC. Target applications include manufacturing plant control, traffic management, localized advertising, as well as crisis management. . Three well thought trials of different scales will be conducted to demonstrate the validity, viability, versatility and soundness of the IPAC embedded framework.

Keywords: middleware for embedded applications,context-awareness,ad hoc communications,rapid application creation,sensors
Pan-European Photonics Task Force: Integrating Europe’s Expertise on Photonic Subsystems (EURO-FOS)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Network of Excellence
Countries involved: Greece,Germany,United Kingdom,Spain,France,Sweden,Netherlands,Sweden,Germany,Italy,Ireland,Italy,Spain,Belgium,Portugal,Denmark
Call:  (FP7-ICT-2007-2, 2007)
Start date: 2008-05-01
End date: 2012-04-30
Duration (months): 48.0
Total project cost (EUR): 5059068.0
EU funding (EUR): 4099895.0
Participants: 18
Project status: CLOSED

EURO-FOS aims at creating a powerful pan-European network on photonic subsystems by clustering top European systems groups with proven track record in the design, development and evaluation of photonic subsystems. EURO-FOS aims at bridging the gap between research on device-level physics and new architectures from the network-level. The first objective of the project is the integration of researchers through exchange and mobility, allowing for innovation and reinforcing common research thrusts. The second objective is the access to expensive infrastructure creating economies of scale in the development and testing of photonic subsystems. The third objective is the strengthening of European research by creating a mechanism for partners to access devices developed in complementary European projects on photonic components. Functional integration of devices will create new ideas through the design and development of new subsystems within the project. EURO-FOS fourth objective is to complement European Commission efforts for combating Europes difficulty to turn scientific know-how developed in universities into exploitable technology. This will be achieved through the creation of an academic pan-European laboratory with strong industrial links. The creation of this lab can bridge the gap created by the shutdown or downsizing of major R&D industrial labs and help innovative SMEs that find it increasingly difficult to allocate R&D expenditure for basic research and expensive testing facilities. EURO-FOS is expected to have a high impact on Europes research through integration of people and clustering of research groups under the guidance of European industry. The creation of a unified and coherent European network of researchers with excellence in this field will ensure that Europe excels in this crucial part of the photonic systems development chain that links device-level physics and network architectures. Moreover, the creation of the pan-European research lab with diverse R&D capabilities, highly-skilled scientific personnel and state-of-the-art testing facilities, will critically assist Europes industry to perform innovative research and evaluate their developed technology in a system environment with advanced equipment and using accurate methods defined by EURO-FOS researchers.

Keywords: integration of researchers,photonic subsystems,infrastructure shared access,virtual lab creation
Divine pairs in ancient Indian scriptures: gender and stylistic expressions of dual deities in the Rgveda (DIVINE PAIRS IN RV)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Slovenia
Call:  (FP7-PEOPLE-2007-4-3-IRG, 2007)
Start date: 2008-10-01
End date: 2012-09-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

This project aims to investigate gender issues and stylistic patterns of divine pairs in the oldest recorded Indian text, the Rgveda. A considerable number of Vedic deities are joined together to form pairs which are expressed in a variety of linguistic constructions. These pairs will be investigated by applying an innovative methodology, combining classical Vedic philology with semiotics, and by examining the causal interconnectedness between the Vedic language and the style of the Rgveda. This research will address the divine pairs, usually of the same gender, in the Rgveda—an unexpected phenomenon from the perspective of other religions—and investigate the links between gender and the variety of stylistic paradigms for dual deities. The project will research different nominal constructions for dual deities as stylistic expressions of the poetic language of the Rgveda. The most significant outcomes of this project will be: new contributions to Vedic studies (i.e., innovative methodology, investigation of gender issues in the Vedic pantheon); publications (a monograph on Vedic dual deities; a series of journal articles and conference presentations); a strengthening of European capacity for research on ancient Indo-European texts; participation in relevant research and teaching programs in the EU and internationally. In terms of relevance for the Work Programme, this project promotes very strongly the transfer of knowledge and skills gained abroad. In addition, it offers a strategic opportunity to capitalize in Europe on research experience acquired overseas by an internationally recognized female scholar. The project will enhance lasting cooperation with Australian academic institutions and contribute to European academic excellence and competitiveness. Reintegration of this researcher into the academic communities of Europe will provide a first-class opportunity to re-import her expertise and facilitate long-term professional stability for her career in the

Keywords: old indian philology,sanskrit grammar,vedic literature,vedic exegesis,ancient indian religions
Highly Accurate Breast Cancer Diagnosis through Integration of Biological Knowledge, Novel Imaging Modalities, and Modelling (HAMAM)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Towards sustainable and personalised healthcare
Action type: Collaborative project
Countries involved: Austria,United Kingdom,Germany,Germany,Switzerland,Netherlands,United Kingdom,Germany,United States
Call:  (FP7-ICT-2007-2, 2007)
Start date: 2008-09-01
End date: 2012-02-29
Duration (months): 42.0
Total project cost (EUR): 4246965.0
EU funding (EUR): 3099723.0
Participants: 10
Project status: CLOSED

Despite tremendous advances in modern imaging technology, both early detection and accurate diagnosis of breast cancer are still unresolved challenges. Today, a variety of imaging modalities and image-guided biopsy procedures exist to identify and characterize morphology and function of suspicious breast tissue. However, a clinically feasible solution for breast imaging, which is both highly sensitive and specific with respect to breast cancer, is still missing. As a consequence, unnecessary biopsies are taken and tumours frequently go undetected until a stage where therapy is costly or unsuccessful. HAMAM will tackle this challenge by providing a means to seamlessly integrate the available multi-modal images and the patient information on a single clinical workstation. Based on knowledge gained from a large multi-disciplinary database, populated within the scope of this project, suspicious breast tissue will be characterised and classified. HAMAM will achieve this by; • Building the tools needed to integrate datasets / modalities into a single interface. • Providing pre processing / standardization tools that will allow for optimal comparison of disparate data • Building spatial correlation information datasets to allow for new similarity and multimodal tissue models. These will be key in the detection and diagnosis of breast cancer • Building in adaptability that allows for the integration of other sources of knowledge such as tumour models, genetic data, genotype, phenotype and standardised imaging. The exact diagnosis of suspicious breast tissue is ambiguous in many cases. HAMAM will resolve this using the statistical knowledge extracted from the large case database. The clinical workstation will suggest additional image modalities that may be captured to optimally resolve these uncertainties. The workstation thus guides the clinician in establishing a patient specific optimal diagnosis. This ultimately leads to a more specific and individual diagnosis.

Keywords: breast cancer,diagnosis,mri,multi modal