Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Wilderness of Time: Timescapes of Contemporary US Literature (WOT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2027-08-31
Duration (months): 36.0
Total project cost (EUR): 288859.2
EU funding (EUR): 288859.2
Participants: 2
Project status: SIGNED

The project “Wilderness of Time: Timescapes of Contemporary US Literature (WOT)” proposes a novel and compelling interpretative framework for US fiction, herein named wilderness of time and which arises from the need to promote a reading of US literature that truly acknowledges its impact in framing the world we live in. WOT reworks and reframes the symbolism of the wilderness by considering time as the dimension in which the wilderness experience takes place nowadays and by retracing this metamorphosis in contemporary literary texts. By doing so, it fills a gap in American Studies, broadening the conception of US identity and culture as seen through its literature, starting from and going beyond its funding myths. WOT thus introduces an innovative perspective for both the scholarship concerning the study of time and temporality in contemporary US literature and that concerning the study of the wilderness, envisioning new ways through which literature can serve as an agent for social change. The research question concerns whether the combination of wilderness and time can provide a much needed framework to understand, through literature, how US identity has been changing, as well as the impact of such change—both within and outside its borders. Thus, WOT would enhance the importance of EU institutions as valuable teaching and research centers (if not as counter-environmental institutions) in this field, to be achieved also through the implementation of sustainable and inclusive teaching/research tools. In the present geopolitical context, this will also bring a crucial contribution to a renovated European vision concerning current societal challenges. Engaging with universities in Italy and in the US and making use of DH tools, the project brings a significant contribution to American Studies by introducing a novel approach on US literature and culture, developed through creative and collaborative practices and methods for teaching and research in this field.

Keywords: wilderness time and literature cultural identity contemporary us literature trauma studies
A Synthesis Oracle for Scalable and Sustainable Porous Nanomaterials (SOSS-PN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium,Brazil
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 200400.0
EU funding (EUR): 200400.0
Participants: 2
Project status: SIGNED

Adoption of new, low-carbon processes like adsorption-based separation and refrigeration is essential to drive Europe’s net zero transition and achieve the targets of the European Green Deal. Advanced porous nanomaterials like metal-organic frameworks (MOFs) are key enabling technologies to achieve this goal, however their adoption is stymied by a chicken-and-egg problem: identifying the most cost-effective MOF for each application, and investing sufficient research time to reduce synthesis costs for the best candidates. In this fellowship I will address this dual challenge by developing a holistic platform to systematise MOF synthesis methodology research, hence both accelerating and generalising the hunt for an optimal synthesis method. Using a combination of text mining and molecular simulations, I will construct a semantic knowledge graph representation for the synthesis of the common MOF UiO-66, creating a database of synthesis methods connected to to material quality profiles. Once created, I will develop a UiO-66 synthesis “oracle” – a machine learning model which can generate novel synthesis procedures from target material quality profiles. I will then refine the synthesis oracle functions experimentally using Bayesian active learning to identify the global optimum synthesis parameters with respect to several quality metrics. Finally, I will transfer the UiO-66 synthesis oracle to a family of related MOF materials, using further lab synthesis and active learning to fine-tune the quality of these secondary MOFs. This new paradigm in nanomaterial synthesis optimisation will be transformative in the field of synthesis optimisation and intensification, representing a novel approach that is generalisable to any synthesis target. In turn, completion of this fellowship will perfectly position me to transition into an independent academic career at the interface of digital chemistry and process intensification.
Life of Giant Phages (GIAPHAGE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Environmental B iology, Ecology  and E volution
Panel description: For all organisms : Ecology, biodiversity, environmental change , evolutionary biology, behavioural ecology, microbial ecology , marine biology, ecophysiology, theoretical developments and mod elling
Countries involved: Finland
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2023-11-01
End date: 2028-10-31
Duration (months): 60.0
Total project cost (EUR): 1499808.0
EU funding (EUR): 1499808.0
Participants: 1
Project status: SIGNED

Bacterial viruses, phages, are ubiquitous and most numerous entities in the biosphere. Development of sequencing techniques has increased our understanding on the diversity of phages that have not been isolated due to lack of cultivable hosts and/or suitable isolation methods. While sequence data enables a better view to the viral diversity, at the same time lack of functional data and biological connection increases. Recently, different studies have found megaphages (mainly phages with a genome over 600 kbp) by assembling metagenomes from various environmental samples. However, no such isolates have been obtained thus far meaning that their characteristics and host interactions are completely unknown. In this ERC project, I will enlighten the life of giant phages, the term I coined for both jumbo and megaphages. I will achieve this by using the first megaphage isolates that I have isolated from boreal freshwaters. During the project, evidence on the megaphage structure, the host interactions and symbiotic relationship with host will be provided. Using a unique set of different phage sizes infecting the same host I will determine the size correlation to different life history traits. I will provide insight to the mutualistic relationship between bacteria and their viruses and reveal new mechanisms behind phage competition. I will also determine the environmental preferences for the megaphage emergence and abundance in boreal freshwaters. In this proposal, I aim to understand How, Where and When megaphages are isolated. Consequently, results will aid in understanding the role of megaphages in other environments such as gut microbiome and potentially provide avenues for developing new genetic tools. This project will open new understanding for microbial ecology and especially phage ecology and the project will create a new field of study under phage biology.
Unravelling Signalling Heterogeneity using DEEP Learning and MECHANIstic Modelling (DeepMechanism)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative B iology : from Genes and Genomes to S ystems
Panel description: For all organis ms: Genetics, epigenetics, genomics  and other ‘omics studies , bioinformatics, systems biology , genetic diseases , gene editing, innovative methods and modelling,  ‘omics for personalised  medicine
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2024-10-01
End date: 2029-09-30
Duration (months): 60.0
Total project cost (EUR): 1499466.0
EU funding (EUR): 1499466.0
Participants: 1
Project status: SIGNED

Signalling enables cells to respond to external cues, but the inherent heterogeneity of individual cell responses, essential for multicellular organization, complicates disease treatment. Heterogeneity arises from drivers at system and molecular scales, intertwined through feedback loops, making quantitative understanding and prediction challenging. I will address this by pioneering transformative computational methods that predict phospho-signalling responses by integrating deep learning with mechanistic modelling to integrate systems and molecular scales. By using unbiased pattern recognition of deep learning models, I will learn cell states and simple phosphorylation rate laws. These will be combined with mechanistic models, integrating biological knowledge, to build simple and interpretable models that predict signalling responses from baseline omics profiles across distinct time-resolved and perturbational conditions. I will apply these methods to investigate drivers of heterogeneity in receptor tyrosine kinase (RTK) and rat sarcoma (RAS) signalling, in response to growth factors and targeted inhibitors in cancer cell lines. I will validate the approach by reprogramming patient-derived organoids using model-proposed inhibitor combinations. The proposed research will advance our fundamental understanding of signalling regulation and co-regulation with cellular states. Given the vital role of RTK and RAS signalling in human health, it also holds the potential for translational impact. More broadly, the proposed computational methods are versatile and could be applied to a broad range of biological and non-biological systems.

Keywords: mechanistic models,ordinary differential equations,cancer,mathematical modeling,signaling,heterogeneity,plasticity,adaptive resistance,targeted inhibitors,machine learning
Fatigue failure mechanism of marine concrete structures using multi-scale numerical modelling (FAMCON) (FAMCON)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom,Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 2
Project status: SIGNED

Floating substructures, e.g. floating offshore platforms, have widely been constructed from steel, as steel’s survivability in the marine environment is well-understood from its use in fixed-foundation offshore wind, but recent discussions in industry have suggested a shift towards the use of concrete due to its lower manufacturing costs, lower carbon footprint and better cost stability. However, lack of confidence in the use of concrete floating structures in a marine environment, particularly its structural performance under fatigue loading, has led to exacting design requirements to ensure their water tightness and durability, leading to excessive thickness that hinders their floatability. This FAMCON project aims to advance understanding of fatigue failure mechanisms of marine concrete using multi-scale numerical modelling, with novelty in integrating information across different scales - from the microstructure of the concrete material to the macroscopic structural response. The project will address the following challenges: 1) simulate micro-scale continuous hydration of cracked marine concrete under fatigue loading, to be able to evaluate the hidden benefit of seal-healing of concrete to its fatigue resilience which have been ignored previously; 2) simulate meso-scale crack propagation mechanism of defected concrete in order to develop the stress-strain constitutive model of concrete with random defects; 3) develop an integrated multi-scale numerical model to investigate probabilistic fatigue performance of marine concrete in order to provide a more realistic fatigue life prediction. This project will not only accelerate the technology readiness level for offshore renewable energies by improving understanding of fatigue life, but also contributes to the longevity and safety of critical marine infrastructure.

Keywords: fatigue solid mechanics marine concrete molecular dynamics simulation
SUpramolecularly engineered functional PERovskite quantum wells (SUPER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 2474375.0
EU funding (EUR): 2474375.0
Participants: 2
Project status: SIGNED

SUPER will develop functional, self-assembled multi-quantum wells based on metal halide perovskites (MHPs) and organic semiconductors integrated at the molecular level in ordered extended solids, creating a hybrid material platform fully exploiting synergistic interactions between the organic and inorganic sublattices with an unprecedented level of sophistication. The resulting materials will have radically enhanced charge transport, improved luminescence yield and extended tunability compared to currently available MHPs, while providing new solutions to the main challenges of toxicity and stability faced by the entire field of MHPs. SUPER will undertake an original supramolecular approach creating a new fundamental understanding of how large molecular and atomic systems interact to form functional superstructures, merging concepts from organic and inorganic synthesis, solid-state chemistry, photophysics, organic electronics and device engineering. The bottom-up construction will start from the synthesis of innovative semiconductor molecular rods with widely tunable energetics allowing fine tuning of the internal energy level alignment, while encoding the structural characteristics regulating intermolecular associations and the controlled supramolecular assembly of the hybrid material. Solid-state nuclear magnetic resonance will be applied as top-notch technique to probe the low-dimensional phases, their defectivity, structural rigidity and local coordination environment with atomic-scale resolution. Advanced optical spectroscopy and charge transport measurements will assess the efficacy of the synthetic strategies establishing a close structure-properties relationship and assisting the material?s refinement. Light-emitting diodes and field-effect transistors will be used as final platforms to assess the concerted effect of supramolecular architecture, transport and luminescent properties ensuring the high-technological relevance of the newly-developed materials.

Keywords: metal halide perovskite,solid state nmr,2d semiconductors,optical spectroscopy,light emitting devices
Promoting a JUST transition to GREEN hydrogen in AFRICA (JUST-GREEN AFRH2ICA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Coordination and support actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: Italy,France,Spain,South Africa,Mauritius,Morocco,Kenya,Germany,Nigeria,Netherlands
Call: Research & Innovation co-operation with Africa on hydrogen (HORIZON-JTI-CLEANH2-2022-1, 2022)
Start date: 2023-02-01
End date: 2025-01-31
Duration (months): 24.0
Total project cost (EUR): 999995.0
EU funding (EUR): 999995.0
Participants: 13
Project status: CLOSED

Starting from the R&D/Roadmapping experiences (CEA, HySA, STRATH, IRESEN) and tools (JULICH, ARTELYS, IME, UNIGE) of consortium partners as well as the wide network of stakeholders at AU-EU level (thanks to AHP-HYDROGEN EUROPE relevant support), JUST-GREEN AFRH2ICA aims to develop a GREEN HYDROGEN JUST TRANSITION ROADMAP (based on the analysis of different AU green H2 scenarios analysed at socio-economic-technical level as well as inspired by EU Hydrogen and Just Transition Programmes) also to drive the deployment of future investment and policies in a synergic way between EU-AU. To do so, JUST-GREEN AFRH2ICA will fully involve AU-EU stakeholders also engaging them in a training/capacity building programme (promoted by an UNESCO Chair initiative lead by UNIGE) and stimulating innovation/market opportunities thanks to an open-innovation matchmaking platform (STAM). JUST GREEN AFRH2ICA aims to develop a GREEN HYDROGEN JUST TRANSITION ROADMAP that would make AU-EU transition pathways to H2 synergic, sustainable (from environmental and social point of view) and avoiding any “new EU hydrogen colonization” of Africa, but promoting a mutual benefit collaboration of the two continents towards the development of independent and collaborative H2 economies, R&D ecosystem and value chains. JUST GREN AFRH2ICA aims indeed to be the “stepping stone” of a collaborative H2 roadmap that, based on the analysis of different AU green H2 scenarios analysed at socio-economic-technical level via partners’ tools (also assessing local resources – RES and water mainly as key for green H2 production) , will also drive future investment and policies as well as the setup of local manufacturing lines. Project final outcome will be a set of 2030-2040-2050 AU roadmaps that, duly aligned with EU ones, will pave the ground to the two continents’ hydrogen transition with a key common aspect: sustainability from an environmental and social point of view to guarantee a Green Hydrogen Just Transition.

Keywords: roadmapping,modelling,open innovation,policy,capacity building,training,matchmaking,financing,lca,manufacturing
Advancing the Digitization and Analysis of Dynamic Cultural Heritage Objects (KINETIKA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Innovation actions
Countries involved: Spain,Finland,Netherlands,Estonia,Cyprus,Austria,Belgium,Greece,Serbia,Norway,Portugal
Call: A European Collaborative Cloud for Cultural Heritage – Innovative tools for digitisation and analysis of dynamic processes, objects and complex combined data (HORIZON-CL2-2024-HERITAGE-ECCCH-01, 2024)
Start date: 2026-01-01
End date: 2028-12-31
Duration (months): 36.0
Total project cost (EUR): 6848553.68
EU funding (EUR): 5858073.11
Participants: 18
Project status: SIGNED

KINETIKA embraces Industry 4.0 concepts to create a groundbreaking 4D digital twin framework for cultural heritage (CH) objects with mechanical parts, focusing on movable structures of industrial heritage and cultural heritage masonry. By integrating advanced imaging - photogrammetry, laser scanning and muography - KINETIKA captures both the physical form and internal complexity of objects, reflecting their dynamic nature. Through IoT-based sensor networks, the project continuously monitors structural integrity, environmental conditions, and mechanical performance, feeding data into AI-driven analytics for anomaly detection, predictive maintenance, and conservation strategies. The core principles of the 4D Digital Twin include accurate 3D representation, displacement or strain estimation, functional simulation, predictive failure analysis and time-based evolution modelling. These capabilities are enhanced by advanced computer vision and AI algorithms, enabling new levels of study and engagement with CH assets. KINETIKA also emphasises interactive and cross-media engagement, combining 3D models, images, sensor data and simulations to create immersive experiences for researchers, educators and the public. Collaboration between the cultural and industrial sectors is central, with KINETIKA's platform being seamlessly aligned with the ECCCH framework to ensure data interoperability. Third-party CH service providers will offer and consume specialised services through a secure interface, enhancing the ECCCH data while tailoring solutions for different heritage professionals. The project will validate its innovations through representative case studies, including clock towers, looms and drawbridges, demonstrating the platform's adaptability and guiding further applications across a wide range of cultural artefacts.

Keywords: heritage digital twin,mechanical parts,multi physics simulation,finite element analysis,neural radiance fields,failure prediction,marketplace,dtaas
The International Market of Jewish Manuscripts and Books (1900-1948) (BookSHUK)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States,Netherlands
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-09-01
End date: 2027-08-31
Duration (months): 36.0
Total project cost (EUR): 288859.2
EU funding (EUR): 288859.2
Participants: 3
Project status: TERMINATED

The encompassing objective of BookSHUK (“book” and “shuk,” in Hebrew “market”) is to provide the first historical and transnational analysis and digital visualization of the scholarly and trade networks related to the market of Jewish manuscripts and early printed books from the beginning of the twentieth century to the aftermath of WWII and the foundation of the State of Israel. Although the last decades have seen a rich harvest of studies on a multitude of aspects concerning the history of the Jewish book from the Middle Ages to the Holocaust, in-depth research on the market in the twentieth century has been largely neglected. BookSHUK aims to assess the international and interconnected nature of networks involving market actors (such as antiquarians, booksellers, private dealers, auction houses, collectors, scholars, librarians) between Europe, Mandatory Palestine (then Israel), and the United States also reflecting on the impact that major historical events such as WWI and WWII had on the trade. Through archival research on selected cases of study concerning sellers, customers, and objects across Europe, Israel, and the United States, the project intends to: a) identify the sellers and their business networks; b) unravel the role of auction houses in the international trade of Jewish manuscripts and early printed books; c) reconstruct the interests and taste that drove customers – both privates and librarians acting on behalf of libraries – to purchase specimens or collections for their private and/or institutional libraries; d) trace back relations among sellers and customers while providing geographical, chronological, and data visualizations of their connections thanks to digital tools, thus contributing to a more inclusive intellectual and cultural history. The three-year MSCA-GF will bring me to the University of Pennsylvania, the University of Modena and Reggio Emilia, and, during a secondment, to the University of Amsterdam.

Keywords: book history,jewish history,digital humanities,libraries