Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Photoanodes advanced by cost-effective catalysts to secure future Solar Hydrogen (PacemCAT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Hungary,Ukraine,Greece,France,Poland,Sweden,Romania
Call: MSCA Staff Exchanges 2023 (HORIZON-MSCA-2023-SE-01, 2023)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 1364228.57
EU funding (EUR): 1200600.0
Participants: 9
Project status: SIGNED

In the realm of renewable energy, the generation of hydrogen via photo- and electrochemical water splitting has emerged as a focal point for energy storage and emissions reduction. However, achieving the desired efficiency remains a formidable challenge, primarily due to constraints in the performance of the anodic reaction involving the endergonic oxidation of water and the subsequent release of oxygen. Despite recent strides, current catalysts are either prohibitively expensive, or suffer from inadequate stability and durability. To address this pressing issue, an interdisciplinary and intersectoral Consortium comprised of seven academic and two industrial teams endeavors to pioneer a breakthrough solution. Our goal is to develop novel materials with enhanced catalytic activity in electrochemical and photochemical water oxidation reactions, coupled with stability under operational conditions. These materials will be rooted in polychelate, macrocyclic, and clathrochelate complexes of 3d-elements. The project will pursue systematic synthetic strategies to obtain the desired water oxidation catalysts, followed by comprehensive characterization employing various analytical, structural, and physico-chemical methods. By elucidating the factors influencing the catalytic efficiency of water oxidation catalysts, the Consortium aims to facilitate the rational design of novel photo- and electrocatalytic systems for hydrogen and oxygen production from water. Furthermore, pathways for leveraging these new substances as highly effective homogeneous and immobilized molecular catalysts for photo- and electrochemical water splitting will be explored, fostering innovative technological solutions for energy conversion and environmental preservation. Through this staff exchange program, we anticipate promoting and enhancing the complementarity of the participating teams, fostering cross-fertilization, and cultivating a hub of synergy in research, innovation and technology.

Keywords: artificial photosynthesis,renewable energy,water splitting,molecular catalysis,cost efficient catalyst,macrocyclic complex,clathrochelate,high entropy alloys,
BIODIVERSITY AND TRANSFORMATIVE CHANGE FOR PLURAL AND NATURE-POSITIVE SOCIETIES (BIOTraCes)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Research and Innovation actions
Countries involved: Netherlands,Sweden,Portugal,Hungary,Spain,Lithuania,Italy,Romania,Germany
Call: Understanding the role of behaviour, gender specifics, lifestyle, religious and cultural values, and addressing the role of enabling players (civil society, policy makers, financing and business leaders, retailers) in decision making (HORIZON-CL6-2022-BIODIV-01, 2022)
Start date: 2022-12-01
End date: 2026-11-30
Duration (months): 48.0
Total project cost (EUR): 4620652.5
EU funding (EUR): 4620652.5
Participants: 11
Project status: SIGNED

BIOTraCes develops knowledge, tools and novel approaches that enable transformative changes (TC), necessary for achieving a nature positive society. We aim to contribute to more inclusive, effective and just public policies, local strategies and corporate concerns on biodiversity aligned with the European Green Deal and SDGs. To this end, we will engage with diverse stakeholder networks around 9 transformative biodiversity innovations in high-impact sectors - agriculture & food, forestry, water, and urbanisation. These local case studies across Europe will help understand in context how plural and often marginalized values, identities (intersectionality), and knowledge systems, concerning living with and caring for nature, can shape behaviour. The case studies will create a portfolio of good and failed examples by discerning power lock-ins, leverage opportunities and enabling actors, and by testing co-produced interventions. Also, we will analyse indirect drivers of biodiversity loss: structural factors and lock-ins that constitute barriers to sustainable decisions and behaviour. A Theory of Transformative Change (ToTC) will synthesise our findings, showing steps on the path to biodiversity recovery and informing public and private strategies and approaches for initiating, accelerating and (up)scaling TC. BIOTraCes’ originality is threefold: 1) An approach of transdisciplinary collaboration, based on action research, co-production and co-learning. 2) Operationalising in research and action principles of pluralising (acknowledging variety in values), empowering (enhancing agency of marginalised groups), politicising (unveiling the political dimension of obstacles towards TC) and embedding (bringing TC into the economy, social practices and policy). 3) A focus on achieving impact through a ToTC approach, which led us to establish an Influencer & Stakeholder Board. Close alliance with the science-policy interfaces and interproject collaboration suit our vision well.

Keywords: biodiversity transformative change action research values leverage social innovation engagement plurality marginalised groups power behaviour consumption production governance nbs sdgs
In Vivo CRISPR-Based Nanoplatform for Gene Editing: A New Disruptive Avenue for Non-Invasive Treatment of Genetic Brain Diseases (BrainCRISPR)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Israel
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-06-01
End date: 2027-05-31
Duration (months): 60.0
Total project cost (EUR): 2249895.0
EU funding (EUR): 2249895.0
Participants: 1
Project status: SIGNED

Genetic brain diseases are among the most devastating and fatal diseases, typically having only palliative treatments and no cure. The revolutionary CRISPR/Cas gene editing technology provides a new horizon and enormous potential for treating such diseases. However, efficient and safe delivery of CRISPR machinery to diseased cells within the brain is one of the greatest challenges in medicine today. Here, I plan to expand far beyond the state-of-the-art, and propose a game-changer approach for this unmet need: A breakthrough nanoplatform, which will transform CRISPR into a clinically-relevant, non-invasive technology, enabling therapeutic genome editing in the brain. Our proof-of-concept results serve as the baseline of this pioneering research project, revealing the exceptional capabilities of insulin as a key to overcoming formidable brain and cell barriers. We will harness these unique abilities within the novel nanoplatform, and shuttle CRISPR machinery across the blood-brain barrier, transport it into deep brain regions, and mediate its successful entry into specific diseased brain cells, leading to highly effective gene editing. The nanoplatform will be designed to meet key criteria for non-invasive, safe and efficient delivery of CRISPR to the brain, while conferring a high degree of modularity and compositional heterogeneity - thus providing both universal and patient-specific components. The nanoplatform will be thoroughly investigated in primary brain cells, 3D organoids, and case-studies of monogenic brain disease models. This comprehensive research will culminate with a universal and modular BrainCRISPR nanoplatform, and delineate design principles for its precise tailoring to specific needs of different brain diseases. Overall, this research will provide in-depth fundamental knowledge and have a transformative effect on applying CRISPR in brain, whilst opening a wide array of possibilities with broader impact on genetic brain therapy and beyond.

Keywords: nanoparticles for drug delivery,nanotechnology,nanomedicine,crispr,drug delivery to the brain
Characterisation and design of RNA-lipid interactions for RNA therapeutics (RNA-lipid)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 206887.68
EU funding (EUR): 206887.68
Participants: 1
Project status: SIGNED

RNA is a ubiquitous biomolecule with a broad range of activities crucial for keeping cells alive. Understanding how RNA bioactivity is controlled is vital for elucidating its roles and applications in molecular biology. RNA, in order to maintain a correct activity patterns, has to be organized. Despite sufficient knowledge about RNA spatial organization within cells via RNA-protein interaction-based processes not much is known about other mechanisms. Revealing the RNA-localization patterns without RNA-binding proteins would create the new branch of interactomics which might have significant implications in the molecular biology and RNA-based therapeutics development. Recently I described that lipid membranes can act as a scaffold for RNAs in a sequence and structure dependent binding process leading to the changes of the RNA activity in vitro. Here, I propose that lipid membranes act as a selective RNA scaffold in vivo. In the following project I will develop a library of membrane-binding RNAs using in vitro selection approach. I will characterize the mechanisms, selectivity, and stability of RNA-lipid binding in bulk and in nano-scale level using self-developed binding assays and super-resolution microscopy, respectively. Furthermore, obtained lipid-binding RNAs are going to be artificially introduced to the existing mRNAs in order to spatially organize protein expression both in vitro and in vivo. The RNA RNA-lipid encapsulation efficiency will be characterized using recently developed single-particle profiling platform. Lastly, I will use gathered knowledge to livetrack the uptake and improve the RNA-based therapeutics (i.e. RNA-lipid nanoparticles) in order to increase the RNA stability and decrease the toxicity of the formulation.

Keywords: lipid membranes,rna,rna lipid interaction,mrna vaccines,super resolution microscopy,sted,single particle profiling
SIMPLER - Silent Installation of MonoPiLEs Retrievable (SIMPLER - Simple Installation of MonoPiLEs Retrievable)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator Challenge: Technologies for ‘Fit for 55’ (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-05-01
End date: 2025-12-31
Duration (months): 32.0
Total project cost (EUR): 3508050.0
EU funding (EUR): 2455635.0
Participants: 2
Project status: SIGNED

GBM has developed Vibrojet® as an urgent needed alternative for the hydraulic hammer currently used for installation of offshore wind turbine foundations. Current method has increasingly difficulties to install the much needed larger wind turbines and to comply with stricter regulations. Vibrojet® involves the whole monopile, including vibrating it, jetting the soil below the monopile, and creating a fluidized bed in the hollow monopile. This process is managed by a control system with a high-tech sensor network based on edge computing concepts using deep learning/ artificial intelligence. Vibrojet® reduces the soil resistance temporarily to such an extent that the huge monopile sinks down silent and gentle to target depth under its own weight. Vibrojet® is compliant with regulations and able to install the larger wind turbines very effectively - accelerating the roll out of offshore wind energy farms that are needed to enable the EU achieving its shore green deal goals.

Keywords: machine learning,silent pile driving,system control,robotics,fluidization,sensor technology,deep learning,artificial intelligence,hydrodynamics,high pressure water jet technology,offshore wind energy,machine vision
Creating Actionable Futures (CRAFT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Climate neutral and smart cities
Destination: Climate neutral and smart cities
Action type: Coordination and support actions
Countries involved: Norway,Italy,Netherlands,Czechia,Belgium
Call: Collaborative local governance models to accelerate the emblematic transformation of urban environment and contribute to the New European Bauhaus initiative and the objectives of the European Green Deal (HORIZON-MISS-2021-CIT-01, 2021)
Start date: 2022-05-01
End date: 2025-04-30
Duration (months): 36.0
Total project cost (EUR): 1999775.0
EU funding (EUR): 1999773.0
Participants: 8
Project status: SIGNED

The CrAFt project will place the transition to climate neutrality at the heart of urban stakeholders. We will support the Mission Board on Climate-Neutral and Smart Cities and the H2020 LC-GD-1-2-2020 one-stop platform in designing and deploying Climate City Contracts, based on experience-based knowledge from CrAFt’s 3 Sandbox Cities (Bologna, Prague and Amsterdam) and 70 Reference Cities engaged in testing and sharing knowledge together with cultural, artistic and creative sectors, property owners and tenants, and citizens and communities. We will deliver a “Climate-Neutral and Smart Cities Guidance Package: NEB Edition” featuring at least 160 collaborative local governance models, tools, examples or stories. This will be supported by a NEB-inspired impact model that helps cities to harness the value of inclusiveness, aesthetics and sustainability, as understood within the local contexts of their city, in their transformation towards climate neutrality, in at least 80 local emblematic projects. More than 30 European universities and schools of arts and design will be engaged in supporting their local cities, with more than 100 students engaged in STEAM teams, internships and local capacity building. We will deliver at least 6 policy briefs informing European policy and programmes about the learnings of these activities, and a storytelling campaign to co-create positive and inclusive narratives towards climate-neutral futures, for, with and by citizens and communities. Together, we will create actionable, climate-neutral futures across Europe by supporting the deployment of NEB-inspired collaborative local governance models, leaving no one, and no place, behind.

Keywords: collaborative governance models,societal impact,steam teams,storytelling campaign,next generation think do tank,sandbox cities,city as a commons,revitalising urban spaces,re skilling society
Reconfigurable Heterogeneous Highly Parallel Processing Platform for safe and secure AI (REBECCA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Research and Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: Greece,Netherlands,Spain,Italy,Sweden,Türkiye,Lithuania,Switzerland,Germany
Call: HORIZON-KDT-JU-2021-2-RIA-Focus Topic 1-Processing solutions for AI at the edge addressing the design stack and middleware (HORIZON-KDT-JU-2021-2-RIA, 2021)
Start date: 2023-02-01
End date: 2027-01-31
Duration (months): 48.0
Total project cost (EUR): 8498328.59
EU funding (EUR): 2744319.72
Participants: 25
Project status: SIGNED

REBECCA, a heavily SME-driven project, will democratize the development of novel edge AI systems. Towards this aim, REBECCA will develop a purely European complete Hardware(HW) and Software(SW) stack around a RISC-V CPU, which will provide significantly higher levels of a) performance (e.g., inferences per second), b) energy/power efficiency (e.g., inferences per joule/watt), c) safety and d) security than the existing ones. This will be achieved by utilizing state-of-the-art technologies and by making significant scientific and technological advances in several key relevant domains, including a) processing units, b) hardware accelerators, c) reconfigurable hardware, d) tightly coupled interconnected chiplets e) HW/SW co-design and co-development tools, f) system software, g) middleware, and h) AI libraries and frameworks. REBECCA will significantly contribute to realizing business and societal opportunities by validating and demonstrating its approach on 4 real-world use cases and 2 benchmarks based on real-world applications from the Smart appliances, Energy Generation, Infrastructure Inspection, Avionics Automotive and Health domains. In terms of HW, REBECCA will develop a novel chip consisting of two tightly coupled chiplets which will incorporate: a) RISC-V multicore, b) Neuromorphic AI Accelerator, c) Programmable array AI Accelerator, d) AI Accelerator utilizing a hierarchical processing architecture, e) DNN Accelerator, f) Reconfigurable hardware, g) Near-Memory-Processing, h) Memory Encryption. In terms of SW, REBECCA will implement optimized system SW, middleware, and AI libraries that will take full advantage of the underlying novel HW. The REBECCA platform will be complemented by a novel HW/SW Design Space Exploration tool which will allow the development of highly efficient REBECCA-based systems. REBECCA will additionally provide the means for safety and security modeling and verification for the developed HW and SW from the very early design stages.

Keywords: edge ai chip,ai hardware accelerators,reconfigurable logic efpga,risc v processing units,multi chiplet integration,interposers,hypervisors,runtime systems,ai libraries
Ecological and Decolonial Feminist Approaches to European Union Critical Raw Materials Policy (GenderedMinerals)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 232916.16
EU funding (EUR): 232916.16
Participants: 1
Project status: SIGNED

This project fills a significant gap in political ecology literature by critically assessing, through an ecological, decolonial feminist lens, the European Union’s Critical Raw Materials Act (CRMA). The CRMA aims to secure and govern new and existing supply chains for the green and digital transitions. An extensive political ecology and critical development studies literature considers neocolonialism and green imperialism when it comes to Global North and EU efforts to secure mineral supplies in producer countries abroad. While gendered dynamics and a masculine ethos, I hypothesize, play a vital role when it comes to EU critical raw materials regulation and policy, the scholarly literature is sorely lacking a feminist theoretical lens and methodological approach to the CRMA’s material and symbolic dimensions. The project objective is therefore to bring an ecological feminist lens to the EU’s growing involvement in securing and governing supply chains of critical raw materials, focusing on the CRMA and its strategic partnership with the Democratic Republic of Congo. This includes examining legal developments, institutional dynamics, and views at EU level, not yet sufficiently explored. Analysis of the role of corporations in the perpetuation of patriarchal, colonial dynamics – through corporate lobbying and action at the epicenter of empire (the EU) – is a key part of this project, given corporate players’ integral involvement with CRMA development. I will creatively combine traditional research methods associated with political science and IR (such as semi-structured interviews and participation in high-level events) with ethnographic and open-ended methods such as participant observation, story-telling, non-linear narratives, and artistic expression. In this manner the project will bring foreground alternative visions of green and just transition, while allowing me to develop my conceptual and methodological skills and profile as an ecological feminist researcher.

Keywords: critical raw materials global supply chains european union democratic republic of the congo ecological feminism
Electrified CO2 Hydrogenation by in-situ Joule Heating: From metal skeleton catalysts to the thermo-electric catalytic mechanism (ECO2HJH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-07-01
End date: 2028-06-30
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 1
Project status: SIGNED

Massive emissions of greenhouse gases (mainly CO2) are strongly linked to the current global warming and climate crisis. CO2 hydrogenation has emerged as one of the most promising approaches to reducing greenhouse effect by converting CO2 into value-added fuel or chemicals. While the reaction is still challenging due to the chemical inertness of CO2, the lack of efficient catalyst and high energy consumption for CO2 activation. This project proposes a new method of using in-situ Joule heating of metal skeleton catalyst to improve CO2 conversion and reduce energy consumption. The metal skeleton catalyst is heated by itself based on Joule's law when applying an electric current. Besides the Joule heat, it potentially increases oxygen vacancies and H* species for activating CO2, which produces the electro-catalytic effect. This new method performs the thermo-electric dual catalysis to promote CO2 conversion. Furthermore, in-situ Joule heating has a small hot zone and reduces energy loss. Owing to these advantages, this method has great application prospect. However, it has rarely been investigated, and the catalyst design and optimization, thermo-electric catalytic mechanism are not clear. To better use it, three work packages will be conducted in this project. The three-layer metal skeleton catalysts will be first synthesized and analyzed. Then, the properties of pulsed/continuous Joule heating (PJH/CJH), and their catalytic performances of CO2 hydrogenation to CO (RWGS) will be tested to establish catalyst structure-performance relationship. Thirdly, the thermo-electric catalytic mechanism will be elucidated by various Operando methodology (such as X-ray absorption fine structure (XAFS), Resonant X-ray inelastic scattering (RIXS)) and first-principles calculations. The research will serve as a critical technique in CO2 hydrogenation, hydrogen economy and green electricity storage ("Power to X"), which will power the carbon neutrality in the EU, UK and beyond.

Keywords: co2 hydrogenation in situ joule heating metal skeleton catalyst thermo electric catalytic mechanism operando characterizations