Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Reproducing Europe: Migrant Parenting and Questions of Citizenship (MigrantParents)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Netherlands,Netherlands
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-11-01
End date: 2020-10-31
Duration (months): 60.0
Total project cost (EUR): 1498425.0
EU funding (EUR): 122518.05
Participants: 2
Project status: CLOSED

This project is an anthropological study of citizenship in a Europe where the presence of migrants has increasingly come to be seen as a burden or threat. This project examines how citizenship is debated, produced and negotiated in this context. It does so through a multilevel study of debates, interventions and practices related to migrant parenting in Paris, Milan and Amsterdam. The experiences of Egyptian migrant parents – a relatively new North African and (partly) Muslim migrant group – serve as its vantage point. Migrant parenting provides a new and fertile angle to explore questions of citizenship, understood here as membership and participation in the nation. Migrant parents are frequently seen as potential threat to the reproduction of the nation, and may thus be targeted by a variety of citizenship agendas designed to ensure the proper reproduction of citizens. This research examines how migrant parents engage with such agendas. It thereby studies the intersection of 1. political debates regarding migrant parents and the nation, 2. interventions through which states regulate and shape the reproduction of citizens, and 3. everyday interactions in the context of parenting. Theoretically, this research will advance theories of citizenship through its innovative focus on migrant parenting, enabling an understanding of how correspondences between family and nation impact citizenship. It also contributes to citizenship studies through its innovative multilevel analysis, which details how citizenship is produced at the intersection of political debates, institutional interventions, and everyday interactions. Additionally, its comparative design enables an assessment of the impact of particular political debates and institutional arrangements on citizenship in Europe. This study will thereby further our understanding of the complex set of conditions that shape social life in contemporary European cities.

Keywords: citizenship,migration,europe,parenting,anthropology of policy
KidsSurgicalPlan: An Internet enterprise for sketch-based cardiovascular pre-surgical planning (KidsSurgicalPlan)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Türkiye
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-06-01
End date: 2016-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Approximately 1 in 100 children are born with a clinically significant congenital heart defect representing 47,000 children each year in the EU. Survival of the newborn requires series of complex open-heart surgeries where optimal hemodynamic performance is essential for improved post-operative quality of life. This work proposes a new computationally-enhanced interactive system for patient-specific pre-surgical design and optimization of pediatric cardiovascular surgeries. With the proposed system, clinicians will be able to rapidly implement a contemplated intervention on a patient-specific 3D computer model without execution. A novel interface will allow clinicians to communicate their surgical intentions directly on the computer model analogous to the way they would communicate their intentions to other clinicians or bioengineers. Basic cardiovascular research on embryonic biomechanics that is being investigated in the parent ERC project will provide the essential foundation of the proposed predictive capability. This interactive framework will be deployed to the web for worldwide impact. Based on market analysis our proposed business model becomes profitable in a short time. PoC project will provide necessary resources for developing the prototype patient-specific surgical-planning framework, clarification of regulatory pathways and follow-up pre-clinical research design.

Keywords: congenital heart defects,blood flow,hemodynamics,vascular growth,pediatric cardiovascular surgeries,patient specific,cardiovascular fluid dynamics,cardiovascular medical devices
Healthscaping Urban Europe: Bio-Power, Space and Society, 1200-1500 (HealthScaping)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Netherlands
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-11-01
End date: 2022-10-31
Duration (months): 60.0
Total project cost (EUR): 1998004.0
EU funding (EUR): 1998004.0
Participants: 1
Project status: SIGNED

Medieval public health is mired in modern myth: without centralized governments, democratic values and advanced medicine, promoting health at the population level was purportedly either unthinkable or simply impractical. Offering a radically different view, HealthScaping will document, analyze and disseminate knowledge about preventative public healthcare between 1200-1500, an era of accelerated urbanization followed by massive demographic decline, with the onset of Black Death (1347-51). This long-term and comparative perspective will fundamentally revise the narrative of European public health by tracing the development and impact of pertinent government policies, medical discourses and social and religious action in the continent’s two most urbanized and richly documented regions, Italy and the Low Countries. The project taps numerous written, material and visual sources and archaeological data from several sites, and examines them also by critically engaging the insights of governmentality studies, cultural-spatial analysis and actor-network theory. A multidisciplinary team, working in a Geographical Information Systems environment and generating innovative urban health maps, will recover earlier societies’ struggles with domestic and industrial waste, travel and labor hazards, food quality, and social and religious behaviors considered harmful or dangerous. As such, the project’s implications will be broad and profound, for it will 1) dislodge bio-power from its accustomed place in modernity; 2) historicize the concept of the public sphere from a health perspective; and 3) challenge the privileged role given to epidemic disease as a catalyst for environmental interventions in premodernity. It will also 4) generate new insights for public health scholars and practitioners working today around the globe, by rethinking the feasibility of preventative interventions under highly diverse forms of government, culture and topography.

Keywords: urban history,public sphere,modern divide
ERA-NET Cofund Electric Mobility Europe (EMEurope)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: ERA-NET Cofund
Partnership: EMEurope (ERA-NET)
Countries involved: Austria,Italy,Germany,Spain,Spain,Italy,Israel,Germany,Finland,Hungary,Poland,Sweden,Türkiye,Belarus,France,Netherlands,Netherlands,Denmark
Call: ERA-NET Co-fund on electromobility (H2020-GV-2016-RTD, 2016)
Start date: 2016-10-01
End date: 2021-09-30
Duration (months): 60.0
Total project cost (EUR): 18972433.22
EU funding (EUR): 6260902.96
Participants: 24
Project status: SIGNED

In collaboration with the European Commission and the European Green Vehicles Initiative Association, European countries and regions will set-up an ERA-NET Cofund to further promote electric mobility in Europe. Electric Mobility Europe builds on the experiences, networks and results of Electromobility+ and is designed to take transnational e-mobility research and policy exchange to the next level. With a two-track approach, the initiative will link research and policy practice in support of electric mobility at the European level. The first of two pillars of Electric Mobility Europe will fund innovation projects focussing on the application and demonstration of e-mobility with the objective of advancing the mainstreaming of the electrification of mobility in Europe. The initiative will bring together about 30 million EUR for supporting applied innovation projects, including up to 10 million EUR of co-funding provided by the European Commission under Horizon 2020. In 2016, the initiative will issue a call for project proposals addressing the key areas of electric mobility: 1. System integration (transport, (sub)urban areas) 2. Integration of urban freight and city logistics in the e-mobility 3. Smart Mobility concepts and ICT applications 4. Public transport 5. Consumer behaviour and societal trends In addition to funding innovation and demonstration projects, the ERA-NET Cofund Electric Mobility Europe will establish a second pillar of activity. The network will provide a platform for cooperation and exchange of information and experiences among participating countries and regions. In this context, know-how will be shared on setting conducive conditions for the development of electric mobility in Europe (e.g. on charging infrastructure). The network will support this by facilitating suitable means of cooperation such as workshops or seminars in order to exchange or coordinate required actions, in attunement with the European Green Vehicle Initiative Association.

Keywords: green vehicles,electric mobility,electric vehicles,electrification of road transport,urban mobility,green mobility,transnational cooperation,demonstration,deployment,sustainable development
Optoelectrical Dynamics of Ion channel Activation in Calcium Nanodomains (NANOPDICS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Spain
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-09-01
End date: 2021-08-31
Duration (months): 72.0
Total project cost (EUR): 1999742.0
EU funding (EUR): 1999742.0
Participants: 1
Project status: CLOSED

In neurons, sites of Ca2+ influx and Ca2+ sensors are located within 20-50 nm, in subcellular “Ca2+ nanodomains”. Such tight coupling is crucial for the functional properties of synapses and neuronal excitability. Two key players act together in nanodomains, coupling Ca2+ signal to membrane potential: the voltage-dependent Ca2+ channels (VDCC) and the large conductance Ca2+ and voltage-gated K+ channels (BK). BK channels are characterized by synergistic activation by Ca2+ and membrane depolarization, but the complex molecular mechanism underlying channel function is not adequately understood. Information about the pore region, voltage sensing domain or isolated intracellular domains has been obtained separately using electrophysiology, biochemistry and crystallography. Nevertheless, the specialized behavior of this channel must be studied in the whole protein complex at the membrane in order to determine the complete range of structures and movements critical to its in vivo function. Using a combination of genetics, electrophysiology and spectroscopy, our group has measured for the first time the structural rearrangements accompanying whole BK channel activation at the membrane. From this unique position, our first goal is to fully determine the real time structural dynamics underlying the molecular coupling of Ca2+, voltage and activation of BK channels in the membrane environment, its regulation by accessory subunits and channel effectors. BK subcellular localization and role in Ca2+ nanodomains make these channels perfect candidates as reporters of local changes in [Ca2+] restricted to specific nanodomains close to the neuronal membrane. In our laboratory we have created fluorescent variants of the channel that report BK activity induced by Ca2+ binding, or Ca2+ binding and voltage. Our second aim in this proposal is to optimize and deploy this novel optoelectrical reporters to study physiologically relevant Ca2+-induced processes both in cellular and animal mode
Mind the Gut: Molecular Markers of Microbiome Evolution (MIND THE GUT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United States,Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2021-03-09
Duration (months): 36.0
Total project cost (EUR): 278227.8
EU funding (EUR): 278227.8
Participants: 2
Project status: CLOSED

What is the role of our microbial partners in our evolution? Does the microbiome evolution reflect major events of human history? Despite increasing evidence that the gut microbiome plays an essential role in multiple core aspects of human biology, little is known about how the human-gut community co-evolved. The role of the microbiome in human evolution and speciation has been historically overlooked, in part due to the challenge of obtaining microbiome data from ancient material. However, understanding the co-evolution of the human-gut ecosystem requires a time-series approach associated with the major defining moments in human evolution such as migrations, admixture, domestication, industrialization and globalisation. Under favourable conditions some archaeological substrates such mummified tissues, coprolites and dental calculus have potential to shed some light on ancient microbiomes. To do so, MIND THE GUT (MtG) will develop new markers of specific bacterial action applying lipidomic and proteomic tools to explore the diagenesis of microbiome substrates. MtG will analyze the mummified microbiomes of the aboriginal Canary islanders. The Canary mummies represent a unique model system to study the impact of diet and lifestyle in populations that evolved isolated but shared their microbiome during the peuplement of the islands. MtG will compare them with a group of naturally mummified bodies from Nubia that span a similar time period, and with modern microbiome samples from 3 african populations with different lifestyles. MtG results will provide a framework for future studies on fossil material and contribute to illuminate the role of the microbiome in overcoming the challenges of diet, environment and lifestyle changes that took place during human history and prehistory. MtG represents a stepping stone to the integration of the ancient microbiomes in the study of human evolution.

Keywords: microbiome,lipids,proteins,diet,lifestyle,mummies,isolated populations,diagenesis
CoachCom2020 – a coaching community enhancing impact of the H2020 SME Instrument (CoachCom2020)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Switzerland,Lithuania,Switzerland,Switzerland,France,United Kingdom,United Kingdom,Luxembourg,Portugal,Denmark
Call: Community building and competence development for SME Instrument coaching (H2020-INNOSUP-2014-1, 2014)
Start date: 2014-09-01
End date: 2016-11-30
Duration (months): 27.0
Total project cost (EUR): 1037710.38
EU funding (EUR): 759856.24
Participants: 10
Project status: CLOSED

Objectives The overall aim of CoachCom2020 is to ensure the fast implementation of a consistent and comprehensive, professional coaching community to support European SMEs participating in the new dedicated SME instrument under Horizon 2020. Workplan and relevance Based on a robust and tested system approach CoachCom2020 will put in place and implement a coaching community methodology and platform with embedded quality assurance measures, ready to tackle the pressing requirements of the first months following the start of the first SME Instrument projects in Fall 2014 and subsequently (WP1). The overall coaching scheme will include highly targeted recruitment communication and broad dissemination reach (WP2), state-of-the-art mechanism for peer-learning in professional communities both on- and offline, structured knowledge sharing under scientific supervision (WP3) and, finally, three classes of pre-validated management systems and tools for Commission and EEN stakeholders: a case tracking / monitoring system; an impacts evaluation / benchmarking system; and a virtual learning platform with both an informal social network dimension and a structured knowledge repository (WP4). An “open-knowledge” policy and open source software are at the heart of the project paving the way for long-term perspectives post-project. Consortium The proposed concept is anchored firmly in the organizational experience and proven excellence of the innovation platform of Western Switzerland – which is coupled to and strongly leveraged by the comprehensive reach and crucial role of the EEN network. The effort is coordinated by a future “end-user” - an experienced, Danish SME coaching organization. Management of the project rests in the hands of seasoned experts. A lean organisation is streamlined for fast decision making and ongoing risk appraisal.

Keywords: business innovation,commercialisation,coaching,mentoring,empowering,network management,international community,peer to peer learning,open knowledge,open source,monitoring,benchmarking
COLOStage : A new prognosis test for the prediction of metastasis in Colorectal Cancer and Hepatocellular Carcinoma (COLOStage)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-03-01
End date: 2016-08-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

ColoStage is a new prognostic test, based on a novel gene expression signature, able to predict robustly the risk of disease relapse after therapeutic intervention in colorectal cancer (CRC) and potentially in hepatocellular carcinoma (HCC). We have previously demonstrated that CRC recurrence and metastasis strictly depend on high TGF-beta signaling (Calon et al., 2012). ColoStage is a gene expression signature that reflects the TGF-beta status of the primary tumor. Therefore, the expression of the ColoStage geneset is tightly linked to the formation of recurrent CRC after therapeutic intervention in CRC. Importantly, Colostage may also aid in the selection of patients for clinical trials who will likely benefit from newly developed drugs that target the TGF-beta signaling pathway in CRC, and possibly in other types of tumors, HCC among others, (potential use as a companion diagnostic test; i.e. Companion Dx). This proposal aims to develop the Colostage Test for competitive use in the clinical setting. This includes validation of the predictive power of the Colostage Test in an independent cohort of patient samples. Worldwide, CRC and HCC are the 3rd and 6th most commonly diagnosed cancers, with nearly 1.4 million and 800.000 new cases diagnosed in 2012 respectively. The primary treatment for CRC and HCC is surgical resection of the tumor. Prescription of chemotherapy depends on the stage of the disease at the time of diagnosis, yet current staging systems have a limited power to predict disease relapse which is usually associated with poor prognosis. Thus, an accurate method for selecting treatment based on aggressiveness and recurrence probability of the tumor such as Colostage will allow to allocate resources in a cost-effectively way and to make existing drug therapies safer and more effective

Keywords: colorectal cancer,hepatocellular carcinoma,prognosis,companion diagnostic,metastasis,tgf beta,disease relapse
C2 Advanced Multi-domain Environment and Live Observation Technologies (CAMELOT)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Strengthen security through border management
Action type: Innovation actions
Countries involved: Spain,Ireland,Ireland,Switzerland,Greece,Poland,Romania,Belgium,Bulgaria,Poland,France,France,France,France,Portugal,United Kingdom,United Kingdom,Portugal,Portugal
Call: Border Security: autonomous systems and control systems (H2020-SEC-2016-2017-1, 2016)
Start date: 2017-05-01
End date: 2021-04-30
Duration (months): 48.0
Total project cost (EUR): 9922586.83
EU funding (EUR): 8020921.26
Participants: 28
Project status: SIGNED

The creation of the Schengen area has been one of the major achievements of the EU. However, this agreement requires countries to cooperate tightly in order to keep a high level of security at their internal borders, as well as to share the responsibility of managing external borders. Such a variety of borders (land, sea and air) and current challenges requires a consistent approach to border surveillance, based on a plethora of heterogeneous assets. These can be manned or unmanned, ranging from sensors (optical, radar, IR) to unmanned platforms (UAV, UGV, USV or UUV), and need to be combined to offer an integrated situational picture of the area under surveillance and of their location. In order to effectively control their operation and manage the large amounts of data collected by them, new approaches for command and control need to be considered, allowing efficient interaction between the operator and the different assets in the field. CAMELOT proposes to develop and demonstrate different advanced command and control service modules for multiple platform domains, based on a SOA architecture that specifies internal and external interfaces, allowing the development of a modular and scalable command and control station, customisable to the user needs. This architecture can be based on results of previous studies and work or open architectures that may prove more suitable and the interfaces can take advantage of the standardisation work that has been done already. After the definition, CAMELOT partners will prototype service modules according to their expertise, background individual technologies and practitioner needs. These will be integrated progressively in specific testing along the project. This prototype development approach will culminate in 2 final demonstrations involving end users and relevant stakeholders, to achieve a maturity of TRL6 (for most individual technologies supporting the functionalities for border surveillance) and an IRL of 7 for CAMELOT.

Keywords: border surveillance,command and control,unmanned platforms,msmdc2