Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
European Network for Research, Good Practice and Innovation for Sustainable Energy (ENERGISE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Robust decision making and public engagement
Action type: Research and Innovation actions
Countries involved: Germany,Ireland,Switzerland,Switzerland,Finland,Bulgaria,Slovenia,Hungary,Netherlands,Denmark,United Kingdom
Call: Social Sciences and Humanities Support for the Energy Union (H2020-LCE-2016-RES-CCS-RIA, 2016)
Start date: 2016-12-01
End date: 2019-11-30
Duration (months): 36.0
Total project cost (EUR): 3720453.75
EU funding (EUR): 3176513.75
Participants: 11
Project status: CLOSED

Considerable challenges remain today regarding Europe´s transition towards a decarbonised energy system that meets the economic and social needs of its citizens. Rebound effects, that is, a full or partial cancelling-out of efficiency gains over time through increased overall energy use, highlight the centrality of consumption in multi-scalar decarbonisation efforts, urgently requiring attention from scientists and policy makers. Calls also abound for innovative, research-led programmes to enhance the social acceptability of energy transition initiatives and technologies. Understanding how culture-specific views and practices and energy policy and governance both shape and reflect individual and collective energy choices is of paramount importance for the success of the Energy Union. ENERGISE responds directly to these challenges by engaging in frontier energy consumption scholarship. Recognising the persistence of diverse energy cultures, both within and between countries, ENERGISE offers an ambitious social science programme to enhance understanding of changes in energy consumption practices across 30 European countries. Moving beyond state-of-the-art research, ENERGISE theoretically frames and empirically investigates socio-economic, cultural, political and gender aspects of the energy transition. It also examines how routines and ruptures (re)shape household energy consumption practices. Adopting a cutting-edge Living Labs approach, designed specifically to facilitate cross-cultural comparisons, ENERGISE fuses tools for changing individual- and community-level energy consumption with a novel method for energy sustainability assessment. ENERGISE will open new research horizons and greatly enhance Europe’s capacity for high-impact, gender-sensitive consumption research. It also offers timely support for public- and private-sector decision-makers who grapple with the design and implementation of measures to effectively reduce household energy consumption.

Keywords: energy consumption,individuals,communities,living labs,interdisciplinary
Advancing Apatite Thermochronology: Novel analytical approaches for high eU apatites. (AAT-NAA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-01
End date: 2018-10-01
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

Low temperature thermochronometry (LTT) dating is a powerful tool in geoscience, used worldwide, to provide unique information on the thermal history of rocks. Using these insights geologists can achieve a better understanding of geological processes that have occurred over million year timescales even in settings where erosion has removed much of the geological record. Despite the success of these techniques in tackling geological problems, there still exists a major gap in our knowledge over the fundamental principles that underlie these dating systems. Much of this uncertainty stems from an incomplete understanding of inter and intra-crystal compositional variation and the influence this has on the kinetics of the dating system. Reaching a complete understanding of crustal thermal histories also remains a major challenge as the lowest temperature thermochronometers, apatite fission track (AFT) and apatite (U-Th)/He (AHe), are only sensitive over a temperature range of c. 120 – 40°C. The lower temperature limit of this range is also dependant on apatites having low degrees of radiation damage that can enhance retention of He within apatite. This project will advance AFT and AHe methodology by focusing on apatites enriched in U and Th from geological settings considered stable. The first goal is to obtain detailed REE compositional analysis using LA-ICP-MS to refine fission track annealing models and obtain high precision measurements of parent elements to improve AFT age data. The second goal is to ensure that the maximum amount of thermal history information is extract from the 4He concentration profile in the apatite crystal. This will be achieved by a combination of 4He/3He analysis and multi-single-grain AHe analysis of broken apatite crystals. By achieving these two goals the project will advance methodology, establish analytical capabilities at the host organisation and provide new insights into the thermal history of the crust at stable geological settings.

Keywords: low temperature thermochronology,isotope geology,tectonics,landscape evolution,geochronology,geochemistry,la icp ms,3he analysis
The Domestication of ‘Hindu’ Asceticism and the Religious Making of South and Southeast Asia (DHARMA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Germany,Italy,France
Call: ERC Synergy Grant (ERC-2018-SyG, 2018)
Start date: 2019-05-01
End date: 2025-10-31
Duration (months): 78.0
Total project cost (EUR): 9820868.0
EU funding (EUR): 9820868.0
Participants: 4
Project status: SIGNED

Censuses report over a billion “Hindus” in the world today. But what is “Hinduism”? In answer, many accounts describe the doctrinal evolutions of various quite different currents of thought. To try to reply using material and social evidence is difficult because so many vital primary sources for institutional history remain inaccessible. What were the material foundations of the constellation of religious movements today classed as “Hindu”? How have different forms of religious agency shaped the institutional and religious landscape of a large sweep of Asia? How did such “Hindu” traditions, associated primarily with the ideas and practices of ascetics questing for liberation, become institutionally rooted? And what were the repercussions of the widespread patronage of pious foundations? Three types of sources will be examined: inscriptions, manuscripts, archaeological remains. Inscriptions are crucial because most of our historical knowledge of early South and Southeast Asia is based on epigraphy. We will explore, mine and diffuse these sources with the tools of digital humanities (rich mark-up of proper-names, technical terms, geodata, etc.). In order to contextualise epigraphy, unpublished prescriptive texts and new archaeological data will be adduced. Our goal is to identify and to map regional and interregional patterns of patronage. The actors are varied: “lettrés”, holy men and priestly intermediaries, as well as their patrons, often grandees of the state; but also cenobitic communities with their statutes, their libraries, their educational activities, and their incipient bureaucracy. Through a comparative approach (concentrating on “Hinduism”, but also considering the so-called “heretic” religions Buddhism and Jainism), and in a broad range of regional contexts, we shall attempt to uncover with unprecedented historical depth the complex interplay of religion, state and society in a formative period, the “Śaiva Age”, between the 6th and 13th centuries.

Keywords: south asia,southeast asia,religion,sanskrit,tamil,kannada,telugu,old javanese,khmer,indology,epigraphy,archaeology,state,society,patronage,indianisation,digital humanities
Lost In translation: Strengthening communication skills between real world and climaTe modEls for seasonal to decadal predictioN (LISTEN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-02-01
End date: 2021-05-03
Duration (months): 24.0
Total project cost (EUR): 168277.2
EU funding (EUR): 168277.2
Participants: 1
Project status: CLOSED

Seasonal and decadal climate predictions are routinely carried out, and are widely used for their numerous socio-economic applications. The improvement of the forecast capabilities at these timescales is the focus of the international effort coordinated by the World Climate Research Programme. The strategy of LISTEN to contribute to this challenge is structured to have two stages. First, it aims at enhancing the transfer of observed information to the model during the initialisation of a forecast. This phase of the climate prediction process is of utmost importance, because it has been shown that a correct initialisation can improve the forecasts up to a few years ahead. However, the systematic errors of the models make this task challenging, because of the discrepancy between the observed and model mean climate. The main consequences are incorrect propagation of systems and a quick loss of the observed information. LISTEN will therefore implement innovative initialisation techniques. These are explicitly designed to tackle specific limitations detected in the methods currently in use. The new techniques will be tested at both seasonal and decadal timescales, and their performance will be compared to the standard methods. The second stage of the project consists in exploiting the data produced by the first stage for an in-depth assessment of the prediction skill, with a special focus over Europe. Large uncertainties remain in predicting events on regional scales, such as heat waves, droughts or heavy rain and snow. LISTEN will aim at a thorough assessment of the model strengths and weaknesses in predicting those events under different initialisation strategies. In particular, the sub-seasonal circulation and extreme weather events will be studied in the framework of circulation patterns, through the analysis of large-scale recurrent patterns of variability (weather regimes). The tools developed to compute these process-based metrics will be made publicly available.

Keywords: seasonal prediction,decadal prediction,initialisation,model bias,extreme events,atmospheric regimes
Tamoxifen mediated protection on X-linked centronuclear myopathy: a mechanistic and pre-clinical study (TAMYOCAL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-01
End date: 2020-04-30
Duration (months): 24.0
Total project cost (EUR): 175419.6
EU funding (EUR): 175419.6
Participants: 1
Project status: CLOSED

X-linked centronuclear myopathy (XLCNM) is a severe congenital myopathy caused by the absence of lipid phosphatase myotubularin. XLCNM affects 1/50.000 male births, there is no treatment and many cases lead to premature death. Thus, treatments are needed. Tamoxifen (TAM) is a selective estrogen receptor modulator that mimics estrogen signalling in skeletal muscle. Pilot study and previous results from the hosting group, have shown that TAM improve muscle symptoms and survival rate in XLCNM mouse model. Results strongly support the idea that TAM protects skeletal muscle via enhancement of estrogenic signalling positively modulating multiple pathways linked to muscle function. However, the exact mechanism(s) is not yet understood. This project aims at elucidating the mechanism(s) of action of TAM and evaluate further its efficacy in XLCNM mouse model. Two specific aims are proposed. First, to determine how TAM acts on pathways and key players involved in XLCNM. Estrogen signalling, phosphoinositide balance, autophagy and mTORC1 signalling will be determined in wild type and XLCNM mice treated and non-treated by TAM. Second, to investigate the pre-clinical efficacy of TAM combined with other compounds in XLCNM mice. TAM extends the lifespan of XLCNM mice according to the pilot study but it prevents only partly leg muscle atrophy, restricting complete functional rescue. Thus, TAM will be combined with other approved drugs that target muscle atrophy (everolimus, creatine, IGF-I and steroids). These parallel approaches will provide knowledge about not-yet explained events related to XLCNM and TAM effects, from molecular to in-vivo level, and instrumental information for other myopathies and rare diseases where lipid phosphatases are missing and phosphoinositide are unbalanced. This knowledge might provide the rationale for new therapeutic options for these dramatic conditions, being highly relevant to patients and families.

Keywords: skeletal muscle,x linked myotubular myopathy,tamoxifen,molecular mechanisms,pre clinical study
DARE Special Needs Lump Sum for ESR1 Rados Keravica (DARE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Action type: Marie Skłodowska-Curie actions
Countries involved: United Kingdom
Call: MSCA Special Needs Allowance (H2020-IBA-MSCA-SNLS-2019, 2019)
Start date: 2019-12-01
End date: 2022-12-31
Duration (months): 37.0
Total project cost (EUR): 6188.0
EU funding (EUR): 6188.0
Participants: 1
Project status: CLOSED

Request of financial support to cover the additional costs that researchers/staff members with disabilities face due to the increased costs of their mobility and/or to ensure necessary assistance by third persons or for adapting their work environment

Keywords: disability access needs
Solutions for largE bAtteries for waterBorne trAnsporT (SEABAT)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Italy,Italy,Germany,Spain,Norway,Norway,Türkiye,Belgium,Belgium,France,Netherlands,Netherlands
Call: Reducing the cost of large batteries for waterborne transport (H2020-LC-BAT-2020, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 9588477.5
EU funding (EUR): 9588476.5
Participants: 17
Project status: SIGNED

The overall objective of SEABAT is to develop a full-electric maritime hybrid concept based on (1) combining modular high-energy batteries and high-power batteries, (2) novel converter concepts and (3) production technology solutions derived from the automotive sector. A modular approach will reduce component costs (battery, convertor) so that unique ship designs can profit from economies of scale by using standardised low-cost modular components. The concept is suitable for future battery generations and high-power components that may have higher power densities or are based on different chemistries. Expected results: optimal full-electric hybrid modular solution, minimising the battery footprint and reducing the oversizing (from up to 10 times down to max. 2 times). Validating as a 300 kWh system (full battery system test) at TRL 5, and virtually validating the solution for batteries of 1 MWh and above, using 300 kWh system P-HiL tests. The result will be a validated hybrid battery solution for capacities of 1 MWh and beyond, a roadmap for type approval and a strategy towards standardisation for (among others) ferries and short sea shipping. The solution will deliver a 35-50% lower total cost of ownership (TCO) of maritime battery systems, including 15-30% lower CAPEX investment, 50% lower costs of integration at the shipyard and a 5% investment cost recuperation after the useful life in the vessel. The SEABAT consortium unites all the necessary expertise for developing the hybrid topology and implementing it in the industry. The market pick-up of the SEABAT solution is maximised by having 20 shipbuilders and integrators in the consortium; they are represented by the SOERMAR association. The stakeholder group, in which end users and port authorities are represented, supports the wide adoption of the SEABAT solution in the European maritime market, and the increase in European skills base in large battery technology and manufacturing processes.

Keywords: hybrid battery system,scalable and modular battery architecture,converter,short sea vessels,ferries
Intelligent Total Body Scanner for Early Detection of Melanoma (iToBoS)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Methods and data
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Australia,Spain,Spain,Israel,Germany,Germany,Spain,Ireland,Sweden,Greece,Belgium,Hungary,Switzerland,France,France,United Kingdom
Call: Digital diagnostics – developing tools for supporting clinical decisions by integrating various diagnostic data (H2020-SC1-2020-Single-Stage-RTD, 2020)
Start date: 2021-04-01
End date: 2025-03-31
Duration (months): 48.0
Total project cost (EUR): 12039139.25
EU funding (EUR): 11683081.25
Participants: 22
Project status: SIGNED

Melanoma is one of the most aggressive cancers that can be discovered at an early stage, and it is responsible for 60% of lethal skin neoplasia. Its incidence has been increasing in white population and could become a public health challenge because of an increase in life expectancy of the elderly population. Total body skin examination, the primary screening mechanism for melanoma, checks each pigmented skin lesion individually in search of typical melanoma signs. This can be a very time consuming technique for patients with atypical mole syndrome or a large number of naevi. iToBoS aims at developing an AI diagnostic platform for early detection of melanoma. The platform includes a novel total body scanner and a Computer Aided Diagnostics (CAD) tool to integrate various data sources such as medical records, genomics data and in vivo imaging. This approach will lead to a highly patient-tailored, early diagnosis of melanoma. The project will develop and validate an AI cognitive assistant tool to empower healthcare practitioners, offering a risk assessment for every mole. Beyond integrating all available information about the patient to personalise the diagnostic, it will provide methods for visualising, explaining and interpreting AI models, thus overcoming the “black box” nature of current AI-enabled CAD systems, and providing dermatologists with valuable information for their clinical practice. The new total body scanner will be based on an existing prototype developed by 3 of the project partners, but powered with high-resolution cameras equipped with liquid lenses. These novel lenses, based on two immiscible fluids of different refractive index, will allow achieving unprecedented image quality of the whole body. The integration of such images with all available patient data using machine learning will lead to a new dermoscopic diagnostic tool providing prompt, reliable and highly personalised diagnostics for optimal judgement in clinical practice.

Keywords: ai cognitive assistant,melanoma,total body mapping,explainable ai,personalised diagnosis,holistic risk assessment
Attosecond space-time imaging of coherent quantum dynamics (ATTIDA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Israel
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-01-01
End date: 2025-06-30
Duration (months): 66.0
Total project cost (EUR): 1690323.0
EU funding (EUR): 1690323.0
Participants: 1
Project status: SIGNED

Coherence is a fundamental property of quantum mechanics, characterizing phase correlations of light or matter waves. It is at the heart of many physical phenomena, such as the creation of electron-hole pairs in the photovoltaic effect or the fast migration of electronic charge within a molecule. In order to study coherent electron dynamics, extremely high spatial and temporal resolving power is required, which is highly challenging. Well-established imaging methods like scanning tunneling microscopy achieve atomic-scale spatial resolution, while lacking ultrafast time resolution. At the temporal frontier, I recently bridged the gap between attosecond spectroscopy (1as = 10-18 s) and the nano-scale. The goal of my research program is to unlock the full potential of attosecond spectroscopy by achieving simultaneous spatial and temporal probing of ultrafast coherent phenomena. The proposed approach relies on the introduction of attosecond spectroscopy into scanning tunneling microscopy and electron holography. The spatial resolution of these methods is based on nano-scale needle tips, serving as local probes or as point-like electron sources. My team and I will develop attosecond temporal gates at the tips, enabling pump-probe spectroscopy. The resulting “pump” – triggering the coherent dynamics – and the “probe” – measuring its evolution – are localized in space and time, with attosecond and sub-nanometer precision. This combination will allow watching charge dynamics in a single molecule and observing multi-electron dynamics in nanostructures with atomic-scale site selectivity, as they evolve in real time. My approach has the potential to shed new light on quantum optics, plasmonics, molecular electronics, surface science and femtochemistry. In particular, my team and I will study quantum tunneling on the atomic level, charge migration in organic molecules and electron-hole dynamics in low-dimensional solid-state systems.