Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The restitution of knowledge: returning African colonial artefacts and decolonizing European museums. An international law perspective. (RestArt)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-04
End date: 2027-09-03
Duration (months): 24.0
Total project cost (EUR): 216240.0
EU funding (EUR): 216240.0
Participants: 1
Project status: SIGNED

The near-monopoly that Western museums have over the possession of the Global South’s cultural heritage represents one of the continuities between the age of colonialism and our time. The common argument of former colonial powers is that, although morally appalling, colonialism was not illegal according to the standards of the time. This leaves unanswered questions regarding possible forms of accountability and the degree of legal responsibility of present-day European states. RestArt challenges this common argument by hypothesizing that at least a part of the colonial practices of domination by Western states was illegal during colonial time. It focuses on the return of African colonial artefacts as a form of redress and relation-building process between the Global South and former colonial states. It innovatively identifies and addresses important gaps in our knowledge by conducting an interdisciplinary investigation into the status of cultural colonial objects held in European museums under international law, analyses recent legal developments in European states and unpacks the legal requests of repatriation of African cultural heritage. RestArt will incorporate and interrogate the legal stance of the communities of origin of colonial artefacts -and especially female voices- on the restitution of cultural colonial objects, an aspect of absolute novelty in the current discourse. RestArt also aims at presenting policy-oriented guidelines to European States and EU institutions to deal with the return of colonial cultural objects. The project will be supervised by Prof. Valérie Rosoux, an international authority in disciplines relating to the legacies of colonialism. Through the training program, the candidate will qualify as a researcher at the intersection of law, political science and post-colonial studies enriching his profile through interdisciplinary research.

Keywords: international law,human rights,colonialism,africa,reparation,restitution of colonial artefacts,transitional justice,postcolonial studies,benin bronzes,museums
Continuous Production of Meso-structured Metal-Organic Frameworks (CPMesoMOF)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Metal-Organic Frameworks (MOFs) are an intriguing class of porous materials with promising applications across energy, environmental, and healthcare sectors. Despite their potential, the large-scale manufacturing of MOFs remains a significant challenge, largely due to the reliance on batch manufacturing methods. These methods often result in products with a wide size distribution, leading to serious operational issues in downstream processes like filtration and drying. Additionally, batch-to-batch variations and the production of nano- to near-micron-sized crystals pose further challenges, particularly in packed bed applications for gas separations. Small-sized MOFs in industrial columns, such as pressure swing adsorption (PSA) units, create higher pressure drops, hindering their ability to operate under industrial conditions (e.g., flue gas, compressed air, higher pressures). In CPM-MOF, we aim to overcome these obstacles by developing a set of standard operating procedures (SOPs) based on chemical engineering principles for the continuous manufacturing of mesocrystal versions of MOFs. Mesocrystals, with their hierarchically crystalline structures formed via the oriented attachment of nanocrystals, self-regulate their size during growth. This process results in a product with a relatively larger size and a narrow size distribution, which are easier to handle in downstream operations and produce a lower pressure drop-in PSA units. The development of SOPs will be supported by process analytical technology (PAT) tools and guided by a novel theoretical framework, ensuring precise control over the manufacturing process. CPM-MOF represents a significant innovation, offering a scalable, sustainable, and economically viable solution to the current limitations in MOF manufacturing. The mesoMOFs produced will be rigorously tested for their effectiveness in addressing critical global challenges such as CO2 capture, O2 separation from air, and H2 storage.

Keywords: metal organic frameworks,mesocrystals,continuous manufacturing,gas storage,gas separations
Accelerating the sustainable production of advanced biofuels and RFNBOs - from feedstock to end-use (FUELPHORIA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Greece,Belgium,Spain,Slovenia,Italy,Serbia,Cyprus,Kenya,Czechia,United Kingdom
Call: Demonstration of complete value chains for advanced biofuel and non-biological renewable fuel production (HORIZON-CL5-2022-D3-02, 2022)
Start date: 2023-10-01
End date: 2027-09-30
Duration (months): 48.0
Total project cost (EUR): 11144321.3
EU funding (EUR): 9678598.55
Participants: 27
Project status: SIGNED

FUELPHORIA will demonstrate the establishment of sustainable complete value chains for advanced biofuels and RFNBOs for providing Europe with sustainable, secure and competitive energy supply schemes. The project will practically showcase a portfolio of nine complete Value Chains which will be set up and tested in real environment contexts with the active participation of all key players including: the feedstock suppliers (two biogas plants, a winery plant, an urban waste treatment plant); the technology providers who will convert through chemical, electrochemical, biological, thermochemical, and photobiological processes the feedstock (CO2, digestate, urban/ municipal biowaste) into an array of advanced biofuels and RFNBOs (light to long parafins i.e. CH4, medium/long chain hydrocarbons, esters i.e. biodiesel, and light alcohols i.e. ethanol, methanol) that meet quality specifications as defined by the end-users in the transport sector (aviation/maritime, road transport) and in the power production sector (gas or oil fired thermal plants), through four DEMOs in Europe (Belgium, Spain, Greece) while European export potential through international collaboration with Africa is also envisaged. Special emphasis will be also given to the logistics around the fuel production systems, i.e., for the sustainable supply of feedstock and the efficient transport of the final products to their end application. To do this, across the FUELPHORIA project the value chain approach is combined with the Life Cycle Assessment approach in order to not only consider all the different stages of the value chain from feedstock to end use but also to explore how the value chain operates as part of a larger system. FUELPHORIA will define and setup business models and marketing concepts and prepare market entry of the technology solutions as well as of the end-products, and will develop policy recommendations for realising the energy system transition potential.

Keywords: advanced biofuels renewable fuels of non biological origin
MEDiverSEAty. In quest of the human dimensions of MEDiterranean Marine Biodiversity (MEDiverSEAty)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,France,Malta,Montenegro,Spain,Greece
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 2496211.2
EU funding (EUR): 2496211.2
Participants: 17
Project status: SIGNED

Sustainable management of Mediterranean Marine Biodiversity is a key-priority of EU programs and actions, with the aim of integrating marine diversity protection and human development. Two main gaps need to be filled to achieve this goal: the overall lack of understanding of European citizens’ conceptions and misconception on the sea; the lack or oversimplification, both in political and scientific debate, of “diversity” as a key driver acting on the relationship among European citizens and marine biodiversity. MEDiverSEAty is a transnational project based on several local case studies with the aim of filling these gaps, through the implementation of a Doctoral Network Training and Research Program in 6 European countries (IT, ES, FR, EL, ME, MT), a novelty in the educational and scientific panorama of marine science and biodiversity management. MEDiverSEAty develops an international, interdisciplinary and inter-sectoral Training Program for 10 PhD Candidates who, in a medium term perspective, will form a community of early career researchers trained in the study of marine biodiversity, via joint research projects in both academic and non-academic settings, with local and network training, open science and complementary skills. The project is based on two key-pillars of contemporary marine sciences, policies and education, with an interdisciplinary approach that tackles the barriers that continue to exist among the biological sciences, the humanities and social sciences, and the study of environmental governance: Ocean Literacy and Marine Biodiversity Conservation. The scientific research objectives of MEDiverSEAty are to develop a common theoretical framework of Mediterranean Marine Biodiversity Conservation which integrates human and biological dimensions and implications, to foster the crucial role of human dimensions in the protection and conservation of Marine Biodiversity and to make Biodiversity the focus of Mediterranean Ocean Literacy.

Keywords: diversity,mediterranean,marine conservation,ocean literacy,training
NeuroModulation Rehabilitation. A neurofeedback and transcranial alternating-current stimulation approach for the neurorehabilitation of patients with attentional deficits after acquired brain injury (NeMoRe)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-09-11
End date: 2025-10-10
Duration (months): 25.0
Total project cost (EUR): 236161.37
EU funding (EUR): 165312.96
Participants: 2
Project status: SIGNED

Acquired brain injury (ABI) represents non-progressive cerebral damage occurring after birth (eg., trauma, hypoxia, stroke). ABIs affect several domains, including cognitive functions. Specifically, up to 80% of ABI patients show attentional deficits that highly impact their quality of life and independence by hampering the execution of daily tasks. Since cognitive rehabilitation seems to be only mildly effective in treating these deficits, it is crucial to explore more effective tools for neurorehabilitation. Among emerging techniques, neurofeedback (NF) can effectively improve attentional abilities in patients with ADHD. NF is a training where a subject receives online feedback on their brainwaves, with the goal to normalize brain oscillations through operant conditioning. It is a promising tool for attention rehabilitation of ABI patients, however, currently only 30% of subjects are able to master NF techniques. Transcranial alternating current stimulation (tACS) is a non-invasive electrical stimulation technique that, by delivering a weak current to the brain, can entrain specific frequencies in the brain. Thus, tACS (by increasing the target frequency of NF) could facilitate NF and increase its effectiveness. Our study has 2 aims: 1) to validate NF as an attentional rehabilitation tool for ABI patients; 2) to show that tACS can increase NF effectiveness. We will perform a randomized double-blind placebo-controlled trial with 75 subjects with ABI (with mixed etiologies, matched by cognitive profile) with 3 arms: a) NF alone, b) NF+tACS , c) Control group. Both tACS and NF will target β power. We will have measures for efficacy, transfer to daily life and motivation of the intervention. This innovative protocol will validate a new tool for ABI patients’ neurorehabilitation and open new doors for the combined use of NF+tACS in other rehabilitation fields.

Keywords: brain injury,non invasive neuromodulation,neurorehabilitation,neurofeedback,transcranial electrical stimulation,attentional processes
Revealing second messenger functions in bacterial stress response, cell differentiation and natural product biosynthesis (SecMessFunctions)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: B iological  Mechanisms , Structures  and Functions
Panel description: For all organisms : Molecular biology , biochemistry, structural biology, molecular biophysics , synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-07-01
End date: 2027-06-30
Duration (months): 60.0
Total project cost (EUR): 1478373.75
EU funding (EUR): 1478373.0
Participants: 1
Project status: SIGNED

Sophisticated signalling systems enable bacteria to occupy almost every single niche on our planet. In such systems, second messengers are crucial information carriers that elicit cellular adaptation to diverse signals. Current dynamics in signalling research have led to the discovery of an exquisite collection of nucleotides that bacteria use as second messengers, including cyclic dimeric adenosine monophosphate (c-di-AMP). A unique feature of c-di-AMP is its essentiality, making it an attractive target for antibiotics. The main objective of this proposal is to uncover the full repertoire of c-di-AMP functions and metabolism in bacteria by using Streptomyces as a model. Streptomyces are our most prolific antibiotic producers and represent an excellent system to study multicellular differentiation. They live in soil, where they encounter diverse environmental cues that trigger antibiotic production and a complex transition from multicellular filaments to spores. c-di-AMP enables Streptomyces to survive osmotic stress caused by rainfall and drought, but interferes with development. How c-di-AMP affects differentiation and how these bacteria adapt to stress signalled by c-di-AMP is unknown. Here, we propose that bacteria use a novel transmembrane signalling pathway to remodel their cell wall for surviving stress mediated by c-di-AMP. We will challenge the current view in the field by showing that the set of enzymes involved in c-di-AMP dynamics is larger than it is currently believed and we will identify new c-di-AMP effectors. Finally, we will explore the potential of c-di-AMP for manipulation of natural product biosynthesis and address the function of a linear di-AMP molecule that is new to signalling research. Our proposed research will not only lead to the discovery of fundamental new principles in bacterial signalling and differentiation but might also identify new cell wall associated targets for drug design and tools for triggering antibiotic biosynthesis.

Keywords: second messenger,natural products,cell differentiation,streptomyces
De novo construction and evolvability of Minimal Lifelike Systems (MiniLife)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Germany,France,Netherlands,Israel
Call: ERC Synergy Grants (ERC-2023-SyG, 2023)
Start date: 2024-02-01
End date: 2030-01-31
Duration (months): 72.0
Total project cost (EUR): 12985066.0
EU funding (EUR): 12985066.0
Participants: 4
Project status: SIGNED

The de novo creation of living systems is a long-standing dream of humanity. To realise this dream, we need a clear conceptualisation of the goal and the experimental means to put it to practice. We think now, time is ripe to make a serious attempt. There is emerging consensus that a minimal living system should be out-of-equilibrium and self-sustaining, have metabolism, an inheritance system, a boundary to keep the constituents together and that a population of such systems should be able to undergo Darwinian evolution. The aim of this proposal is to develop, for the first time, synthetic chemical systems with all of these features. Due to its very nature MiniLife is standing on two, equally strong feet: chemistry and biology. The strongest link between them is autocatalysis, which allows reproduction. Our approach to creating the first artificial chemical living system takes the following steps: (1) Identification of new, and development of existing, autocatalytic (super)systems that function as chemical (and informational) replicators. (2) Coupling of metabolism with chemical replicators. (3) Coupling of autocatalysis to compartment growth and division. (4) Synthesis of a chemical supersystem comprising all three components (replication, metabolism and compartmentalisation). (5) Demonstrating minimal Darwinian evolution upon subjecting the systems synthesized in 1-3 to out-of-equilibrium selection regimes. (6) Approaching a minimal living system by enhancing of the evolvability of the triple systems developed in 4. We have assembled a strong consortium that brings together PIs of previous ERC Advanced Grants in three key areas to be integrated: Ashkenasy and Otto bring expertise in synthetic chemical self-replicating systems; Griffiths brings expertise on compartmentalisation using microfluidics, and Szathmáry is a leading expert on theory of replicator evolution and computational modelling. Success would constitute a landmark achievement in basic science.

Keywords: systems chemistry evolvability autocatalysis infrabiological systems microfluidics error threshold reaction network
Accelerating market uptake of Drone-aided medicAl operations through Living Labs (DALi Lab)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Interconnected Innovation Ecosystems
Destination: Interconnected Innovation Ecosystems
Action type: Coordination and support actions
Countries involved: Spain,Italy,Belgium
Call: Stimulating Experimentation Practices (HORIZON-EIE-2023-CONNECT-02, 2023)
Start date: 2025-03-01
End date: 2026-08-31
Duration (months): 18.0
Total project cost (EUR): 1243691.53
EU funding (EUR): 998224.89
Participants: 9
Project status: SIGNED

Advances in biomedical science, data science, engineering, and technology are leading to high-pace innovation with potential to transform healthcare practices towards improved quality of life for citizens in urban and rural environments. This can be the case of drones supporting medical and healthcare services, whose implementation is expected to bring tangible benefits in short term. However, despite drones have lived significant technological advances and the evolution of the pillars of the regulatory framework, the disruptiveness that their applications bring does not match the readiness of market and non-aviation sectors as well as the readiness and capacity of local authorities. To address this well-known issue, many stakeholders have recognised the urgent need to evolve from sandbox operational project settings to living labs settings as a way to close the gap and involve all the real-life stakeholders. Therefore, there is a need for transition to the establishment of living labs to demonstrate to actors (market and citizens) the real-life improvements of drone-aided medical services. DALi Lab looks for developing detailed requirements for setting up the engagement and governance structure of living labs for drone-aided medical services. This will be achieved designing an action plan to set up a living lab during the project, including testing and validation of drone solutions (real flights and simulations) for medical services for a specific use case. At the end of the project, we will be able to provide guidance on how to develop living labs for drone-aided medical services by integrating drones on medical operations while safeguarding societal acceptance/embracement, tradeoffs and concerns about safety and security, compliance with medical protocols and the protection of individuals/patients as well as privacy and sustainability dimensions (e.g. environmental nuisance, social impacts, economic benefits.

Keywords: living lab,drone aided,medical,logistic,foresight scenarios,replicator,ecosystem,urban air mobility,drone,methodology,social acceptance,local authorities,governance,guidance material