Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Pre-breeding strategies for obtaining new resilient and added value berries (BreedingValue)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Innovation actions
Countries involved: Spain,Germany,Spain,Italy,Germany,Germany,Spain,Italy,Germany,Italy,Italy,Türkiye,Norway,Norway,Finland,France,France,United Kingdom,United Kingdom
Call: Genetic resources and pre-breeding communities (H2020-SFS-2020-1, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 7611738.04
EU funding (EUR): 6986278.5600000005
Participants: 21
Project status: SIGNED

The main objective of BreedingValue is to provide the knowledge and tools to utilize strawberry, raspberry and blueberry GenRes and pre-breeding material for the creation of new breeding possibilities. The achievements are directed to create European cultivars with resilience to different and changing climatic conditions, as well as adaptability to different cultivation systems. Equally important, achievements targeted at producing consumer-desirable fresh-fruit cultivars of berries with high nutritional quality. With this aim the most interesting GenRes available in different EU public and private GenRes collections and breeding programs can be identified and used for the project. The BreedingValue platform will be developed and validated by using strawberry, raspberry and blueberry, being the most important in EU berry industry, known by its high economic impact and potential. This project will apply the most recent technical advances: a) to identify conserved and maintained germplasm of the main genera appropriate for sustainable berry production throughout the EU; b) to apply new and advanced genotyping and phenotyping tools for the characterization of local races and varieties, breeding populations and pre-breeding material; c) to identify the genetic base of the most important resilience traits and fruit quality traits for selecting new cultivars with increased adaptability to different and changing climatic conditions and cultivation systems; d) to develop studies on EU consumers preference; e) to apply Life Cycle Analyses to evaluate the ecological benefits derived by the application of resilient pre-breeding material and varieties; f) to generate a novel efficient data analyses strategy; g) to develop prototype visualization tools; and h) to disseminate and communicate the results to breeders, GenRes managers, researchers , growers, market organizations, consumers, food industries, health authorities and regulatory and legislative authorities.

Keywords: berries,germplasm,breeding material,genotyping,phenotyping,sustainability,berry consumer science,breeding technology transfer,new berry pre breeding material
Network for Medieval Arts and Rituals (NetMAR)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Germany,Cyprus,Denmark
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2021-01-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 899907.5
EU funding (EUR): 899907.5
Participants: 3
Project status: SIGNED

Even though it is a cliché that most Byzantine arts originated in, for and as rituals, scholars largely neglect their ritual origins and functions. Medievalists tend to treat visual, literary and performing arts as distinct from each other. In the medieval world, however, these arts were often combined to produce effective rituals. Recognizing the importance of considering these three arts together, NetMAR will use the concepts of “ritual”, “ritualization” and “performance” to bring together all types of Byzantine arts under one roof. Given the importance of Cyprus within the Byzantine and Western medieval worlds, NetMAR will use the same approach for Western medieval arts where they coexisted and interacted with their Byzantine counterparts. Building on twinning’s huge potential for knowledge transfer, training and exchange of best practices between the three partnering institutions, NetMAR will work towards filling the networking gaps and deficiencies between UCY and its advanced partners in the field of Medieval Studies. NetMAR will also have a dedicated focus towards both promoting the involvement of female and male ESRs in the coordinating institution and strengthening its research management and grant writing skills. Furthermore, NetMAR will participate in the production of new tools and services that will benefit the tourism and culture industry, along with other interested stakeholders and public authorities. The collaboration of the three partners, which mainly aims at strengthening the abilities, networks, skills and knowledge of UCY, will be performed within the framework of a number of CSA including: staff exchanges, expert visits, webinars, workshops, conferences and a summer school, as well as dissemination and outreach activities. These CSA will enable UCY to produce high-impact publications, establish an interdisciplinary, peer-reviewed and open access scholarly journal, and create a critical mass of highly qualified young scholars of both sexes.

Keywords: byzantium,medieval cyprus,medieval studies,visual arts,literary arts,performing arts,rituals,medieval heritage,medievalism
Brain meets spine: the neural origin of toddler’s first steps (Learn2Walk)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-02-01
End date: 2022-07-31
Duration (months): 66.0
Total project cost (EUR): 1331625.0
EU funding (EUR): 1331625.0
Participants: 1
Project status: CLOSED

A child’s first steps may be small, but they are a giant leap for its development. Children have an instinct to walk from the moment they are born – a 'stepping reflex' hardwired in their neural circuitry – but it typically takes about one year before they can start walking independently. In a pioneering work published on Science in 2011, I demonstrated that the coordinated muscle activation in neonate stepping is described by two basic activation patterns that are retained throughout development, and supplemented by two new ones that be-come manifest in toddlers. These seminal findings triggered profound questions: Is the development of new patterns an emergent property, indicative of spontaneously changing cortico-muscular interaction? Does locomotor impairment change the spontaneous character of this emergent property into a gradual one? With the proposed research, I plan to answer these questions by studying the interplay between brain and muscular activity at the onset of independent walking. The overarching aim is to characterize the emergence of independent walking in typically developing children and in children affected by cerebral palsy, and to identify an optimal rehabilitation strategy to promote normal walking in the latter. I plan to perform a combined analysis of brain and muscular activity in typically developing children, unraveling the detailed processes underlying the learning of walking. I will then elucidate the reorganization of cortical and cortico-muscular activity accompanying the altered development of walking in children with cerebral palsy. Finally, I will apply these results to the identification of optimal rehabilitation techniques for children with cerebral palsy. It is my long-term ambition to exploit fundamental insights into neuro-motor control for promoting normal walking in children with locomotor impairments. The proposed project provides an exciting opportunity for me to realize this goal.

Keywords: gait,development,children,cerebral palsy,cortico muscular coherence,functional connectivity,muscle synergies
ERA-Net Cofund on Sustainable Food production and consumption (SUSFOOD2) (SUSFOOD2)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: ERA-NET Cofund
Partnership: SUSFOOD2 (ERA-NET)
Countries involved: Germany,Spain,Spain,Estonia,Ireland,Italy,Germany,Norway,Türkiye,Belgium,Finland,Lithuania,Sweden,Belgium,Romania,France,Netherlands,United Kingdom
Call: ERA-NET Cofund: Public-Public Partnerships in the bioeconomy (H2020-SFS-2016-1, 2016)
Start date: 2017-01-01
End date: 2022-06-30
Duration (months): 66.0
Total project cost (EUR): 14269217.0
EU funding (EUR): 4708841.609999999
Participants: 31
Project status: SIGNED

The aim of SUSFOOD2 is to foster research and innovation in the field of sustainable food systems through enhanced cooperation and coordination between EU member and associated states. It will thereby contribute to the overall EU objective of building the European Research Area as well as a newly emerging Food Research Area. Major challenges will influence future food chains asking for innovative solutions to - respond to increased demand for food by increasing production sustainably (Food and Nutrition Security) - make optimal use of resources while mitigating impact on the environment - reducing losses and waste - follow a whole food chain approach from production to consumption - improving competitiveness of the European agri-food-business SUSFOOD2 focusses on sustainability in post-harvest food production, thus covering relevant fields from natural sciences to food engineering and social sciences. Building on the achievements of its predecessor in FP7, SUSFOOD2 Cofund will strengthen efforts to support and fund excellent research in the food area by one co-funded call of around 11.4 Mio. €. The consortium also aims at implementing other additional activities in a three-fold approach: i) strengthening networking and knowledge transfer among various stakeholders (i.e. by workshops, stakeholder events etc.) ii) additional funding activities without EU co-fund (preferably linked with other initiatives) iii) implementation and further advancement of the SUSFOOD SRA (developed in FP7) With the outlined approach SUSFOOD2 will contribute to - maximizing impact of transnational cooperation pooling resources (material and intellectual) and implementing best practice - using synergies and reducing overlap by interacting with related (international) initiatives (especially JPIs HDHL and FACCE) - Promoting the outputs of SUSFOOD2 network and funded projects via targeted dissemination thus sharing common vision and creating awareness for the field of food sustainability.

Keywords: sustainability,food production,consumption,food chain,food processing,loss,waste,environment,consumer,agribusiness
Designing Next-Generation Aircraft via High-Fidelity Computational Models and Optimization (NextGen Airliners)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-01
End date: 2016-11-30
Duration (months): 18.0
Total project cost (EUR): 138807.0
EU funding (EUR): 138807.0
Participants: 1
Project status: CLOSED

Air transportation is a crucial contributor to the world economy, and thus its continued growth is essential. However, environmental impact and the increase in fuel prices make sustainable aviation a challenge. To address this challenge, we propose to develop state-of-the-art computational tools for the design optimization of next-generation airliners with unprecedented fuel efficiency. We will achieve this by leveraging the expertise of the researcher on high-fidelity computational design of aircraft, together with Airbus’ vast experience in practical aircraft design, and the network of academics at ISAE. The proposed research is expected to make a lasting impact at Airbus by implementing new computational tools, and by developing design concepts for the next-generation of aircraft.

Keywords: aircraft design,multidisciplinary design optimization,numerical optimization,sustainable aviation
Effective green financial policies for the low-carbon transition (GREENFIN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Switzerland
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-01-01
End date: 2025-12-31
Duration (months): 60.0
Total project cost (EUR): 1499771.0
EU funding (EUR): 1499771.0
Participants: 1
Project status: SIGNED

Mitigating dangerous climate change requires a fundamental transition of global economies. This transition calls for an annual investment of 2–4 trillion USD, which is a multiple of current climate investment. Accordingly, the EU and many countries are enacting green financial policies, intervening in the financial sector to improve financing conditions for low-carbon technologies. Examples include green state investment banks, carbon disclosure requirements, and changes to lending regulations. However, the effect of these financial policies on investments in non-financial sectors such as energy, transport, or building is largely unknown. More specifically, we lack insights on how different low-carbon technologies require different types of finance (such as public vs. private finance, corporate vs. project finance, or equity vs. debt). Hence, it remains unclear how to make best use of such policies to fill the climate finance gap. By bridging disciplines and using novel data, GREENFIN will lead to a breakthrough in our understanding of the effects of financial policies on the low-carbon transition in non-financial sectors, and thereby lay the foundations for a new interdisciplinary field of financial policy analysis. First, combining theory from technology innovation studies and financial economics, I will derive how technology-inherent characteristics predict the demand for different types of finance. Second, using policy analysis tools and novel machine learning-based methods, I will analyze the effects of green financial policies on the supply of various types of finance. Third, combining these insights I will deliver specific recommendations for designing more effective green financial policies in the EU and beyond. By including financial policies in policy mix analyses, GREENFIN will crucially increase the overall analytical power of public policy analysis, which is all the more important given the ever-growing role of the financial sector in modern economies.

Keywords: public policy analysis,climate policy,innovation studies,climate finance
A multi-parametric Regulatory T cell Atlas in cancer to predict immunotherapy response, adverse autoimmune events and to identify novel therapeutic targets (RegSign)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Greece
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-01-01
End date: 2025-12-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

The advent of immune checkpoint inhibitors (ICI), that target regulatory pathways in T cells to unleash antitumor immune responses, has revolutionized cancer immunotherapy. However, despite the enormous success of ICI in the treatment of cancer, a significant proportion of patients do not respond, while responses are frequently accompanied by life-threatening autoimmune related adverse events (irAEs). Predictive biomarkers of clinical responses and new therapeutic strategies to harness anti-tumor immunity, while keeping autoimmunity in check represent a currently unmet need. Tregs, are an ideal candidate, since they are physiologically engaged in maintenance of self-tolerance, are the dominant suppressive population in the tumor microenvironment (TME), promote tumor growth, correlate with poor prognosis and importantly, represent a fundamental impediment of cancer immunotherapy success. Building upon my extensive expertise on Tregs in autoimmunity and cancer, the abundance of circulating Tregs in cancer patients, and preliminary data demonstrating a robust transcriptomic and metabolic reprogramming of circulating Tregs in advanced melanoma patients experiencing irAEs, RegSign proposes: 1) to integrate single cell mass-cytometric, transcriptomic, metabolic and stability analysis of circulating Tregs to create a “liquid biopsy” for prediction of ICI efficacy and irAEs development, 2) to identify novel Treg-based therapeutic targets via innovative humanized patient derived xenograft models and 3) to modulate Treg metabolic checkpoints for the management of irAEs. Decoding Tregs signatures in cancer will empower the discovery of personalized predictive biomarkers and novel targets for cancer immunotherapy.

Keywords: biomarkers,cancer immunotherapy,therapeutic targets,regulatory t cells
First liquid tolerant Centric Reciprocating Compressor enabled to Pump (CRCP) (CRCP)

Framework: Horizon 2020 — Societal Challenges
Action type: SME instrument
Countries involved: Norway
Call: H2020-EIC Accelerator pilot –SME Instrument - Green Deal (H2020-EIC-SMEInst-2018-2020-4, 2020)
Start date: 2020-10-01
End date: 2023-02-28
Duration (months): 29.0
Total project cost (EUR): 3305875.0
EU funding (EUR): 2314112.5
Participants: 1
Project status: SIGNED

Current technologies and products in wet gas compression processes have several deficiencies, most importantly related to existing compressors´ high energy consumption, large size, intolerance to handling liquid; and consequent low energy efficiency, potential erosion, and breakdown. These issues become even more complex in some of the challenging for compression industries such as hydrogen production where particularities of the gas are especially challenging to handle in robust, cost- and energy-efficient manner. In turn, limitations of current compression systems prevent the large-scale deployment of hydrogen technologies. OTECHOS liquid tolerant Centric Reciprocating Compressor enabled to Pump (CRCP) project aims to mature and commercialise our breakthrough innovative centric reciprocating compressor – first cost-efficient liquid tolerant compressor combined with pumping action that addresses all the shortcomings of the existing wet gas compression solutions. It is a third to half size smaller than other compressors currently on the market, does not require additional drying units, as well as oil- and valve-free. Additionally, CRCP is being able to operate low speed, securing robust operation, while requiring low maintenance and having a low footprint. CRCP offers to its customers the annual energy savings of minimum 30% and up to 45% less CO2 emissions and reduction of operating costs by 35% in comparison to competing solutions. In broader scale, commercialisation of CRCP will significantly contribute to the EU Green Deal 2030 targets on improving energy efficiency by 5 TWh by 2030 (0.5 % contribution to EU-wide 2030 target) and cutting in greenhouse emission by 4 million tonnes CO2-eq (0.2 % contribution to EU-wide 2030 target). As such, CRCP is the first energy- and cost-efficient compression solution to enable large-scale deployment of efficient and sustainable wet gas compression in industry.

Keywords: hydrogen compressor,wasted heat recovery,centric reciprocating system,co2 reduction,energy,saving,cost reduction
Disorder and Interactions in Topological Floquet Systems (DInTopF)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-04-01
End date: 2023-03-31
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: CLOSED

This project aims at studying the topological properties of ultracold atoms in a periodically-driven honeycomb optical lattice in the presence of disorder and interactions. It relies on an already-existing experimental setup that can routinely create topological Floquet phases with weakly-interacting bosonic potassium atoms. The development of several technical tools will allow for the investigation of yet-unexplored topological phases of matter and bring solutions to the inherent heating due to the periodic driving. A first task is the direct observation of topological edge states and the realization of a Chern number 2 topological phase. This requires the implementation of a box potential and a better control of the laser beams providing the optical lattice. It will provide for the first time a complete picture of the bulk-edge correspondence and of the phase diagram of Floquet systems. A second set of experiments involves the setting of a disorder potential, and will bring into light the interplay between topology and disorder in periodically-driven systems. In particular the existence of disorder-induced topological phases such as the anomalous Floquet Anderson insulator will be demonstrated. In this phase, the bulk is fully localized and topologically-protected edge states do exist. In the last part of the project, a vertical confinement will be implemented, and it will be combined with the tuning of interactions with a Feshbach resonance to bring the system to a strongly-interacting regime. There, interesting phases of matter can be explored, such as a fermionization of the gas loaded in a so-called moat band. More strikingly, a topological many-body-localized Floquet phase can be realized, where the strongly-interacting particles undergo a periodic driving, but are resilient to heating while supporting a topological edge state.

Keywords: topology,floquet systems,quantum gases,optical lattices,many body localization,anderson localization