Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
European Industrial DoCtorate on Offshore WiNd and Wave ENergy (ICONN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland,Ireland,Denmark,Denmark,Denmark
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) (H2020-MSCA-ITN-2015, 2015)
Start date: 2015-10-01
End date: 2019-09-30
Duration (months): 48.0
Total project cost (EUR): 845838.36
EU funding (EUR): 845838.36
Participants: 5
Project status: CLOSED

ICONN is a unique European Industrial Doctorate initiative to meet the current and future demand for highly skilled offshore wind and wave energy engineers by developing and advancing European capacity in the design, development and performance optimisation for Offshore Wind and Wave Energy installations. The initiative is strongly shaped by active participation from industries, and will develop and enhance European capacity in the offshore renewable energy area at a critical juncture in time when Europe strives to occupy a lead market position globally in this sector. The ICONN EID will i) provide state-of-the art training to Early Stage Researchers jointly with industries in the scientific and engineering disciplines of power take-off (PTO) and structural control, wave mechanics and hydrodynamics, CFD, sensing and system identification; ii) advance expertise, and research capacity, in the techno-economic-environmental factors that impact on the reliability and operational efficiency of offshore renewable energy installations; iii) instil business, management, entrepreneurship and innovation skills pertaining to offshore wind and combined wind-wave energy sector to encourage entrepreneurship and innovation; iv) promote clearly defined scientific dissemination, public outreach and commercialisation/IP agendas. The three scientific work packages, which scaffold the individual research activities, progress from addressing specific challenges and capability deficiencies that impede the effective and efficient deployment of offshore wind and wave infrastructures (floating systems and optimisation of power take-off (PTO) ) through to activities that seek to create, and innovate in, new control algorithms and in operational efficiency domain (fatigue control, new algorithms for control of PTO).

Keywords: training wind wave energy offshore turbine energy converter structure control power mechanics,hydrodynamics system identification shm power generator data sea renewable testing reliability
Harnessing clonal evolution in chronic lymphocytic leukemia (CLLCLONE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Switzerland
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-07-01
End date: 2023-06-30
Duration (months): 60.0
Total project cost (EUR): 1940000.0
EU funding (EUR): 1940000.0
Participants: 1
Project status: SIGNED

Chronic lymphocytic leukemia (CLL), the most common leukemia in adults, is addicted of interactions with the microenvironment. The B-cell receptor (BCR) is one of the most important surface molecules that CLL cells use to gain oncogenic signals from the microenvironment. The critical role of BCR signaling for the pathogenesis of CLL is supported by the therapeutic success of ibrutinib, a targeted agent that disrupts the BCR pathway. Beside microenvironment-promoted oncogenic signals, the biology of CLL is also driven by molecular lesions and clonal evolution, that mark CLL progression and treatment resistance. The interconnection between microenvironment-promoted oncogenic signals and clonal evolution has been postulated in CLL but never proven because of the lack of suitable ex vivo models. Ibrutinib allows the unprecedented opportunity of assessing the contribution of cell signaling to cancer clonal evolution directly in vivo in patients. The project working hypothesis is that mutation- and selection-driven clonal evolution is promoted by microenvironment-induced signals, including those propagated from the BCR. According to this hypothesis: i) BCR signaling inhibition due to ibrutinib should stop clonal evolution; while ii) acquisition of by-pass mechanisms that keep ongoing signaling should promote mutation and selection despite BCR inhibition, thus favoring CLL clonal evolution and ibrutinib resistance. In this scenario, the combination of ibrutinib with drugs that overcome by-pass mechanisms could prevent clonal evolution, thus improving treatment efficacy and patient outcome. In order to address our working hypothesis, we will take advantage of clinical trial and co-clinical trial samples to monitor signaling and clonal evolution under ibrutinib and ibrutinib-based combination treatments.

Keywords: leukemia,targeted therapy,clonal evolution,precision medicine,drug resistance
Towards a Complete Quantitative Model of the FOF1 ATP Synthase (F-ATPase)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

The FOF1-ATPase is a complex nanomotor that synthesizes nearly 90% of the ATP made during cellular respiration. It consists of two coupled rotary motors: an integral membrane complex driven by proton flow across lipid bilayers (FO) and an enzymatic complex that converts ADP and inorganic phosphate to ATP (F1). The rotational portion of these motors acts as a camshaft, inducing conformational changes that lead to ATP synthesis in the F1 motor’s three functional catalytic sites. The F1 motor can perform ATP synthesis in the absence of FO, and it can also work in reverse, hydrolyzing ATP to pump protons against an established gradient. Over the last 30 years many important aspects of this motor’s function have been elucidated by careful biochemical work and further understood by clever biophysical experiments. However, there is still not a complete, quantitative description of the whole thermodynamic cycle—one that fully describes the interactions between all three separate catalytic sites and accounts for the need to exchange ATP (found abundantly) for the relatively sparse ADP.

Keywords: atp synthase,atp synthesis,free energy,energy production
New Tools for Terrain Gravimetry (NEWTON-g)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Switzerland,France,Netherlands,United Kingdom
Call: FET-Open research and innovation actions (H2020-FETOPEN-1-2016-2017, 2017)
Start date: 2018-06-01
End date: 2022-11-30
Duration (months): 54.0
Total project cost (EUR): 3405088.75
EU funding (EUR): 3405088.75
Participants: 7
Project status: CLOSED

Poor knowledge of the spatio-temporal changes in the characteristics and distribution of subsurface fluids remains an insurmountable barrier to addressing important societal issues, including: sustainable management of energy resources (e.g., hydrocarbons and geothermal energy), management of water resources, and assessment of hazard (e.g., volcanic eruptions). Gravimetry is highly attractive because it can detect changes in subsurface mass, thus providing a window into processes that involve deep fluids. However, high cost and operating features associated with current instrumentation seriously limits the practical field use of gravimetry. NEWTON-g proposes a radical change of paradigm for gravimetry to overcome such limitations. We aim at developing a field-compatible gravity imager able to real-time monitor the evolution of the subsurface mass changes through continuous images of the gravity field. This system will include an array of low-costs MEMS-based relative gravimeters anchored on an absolute quantum gravimeter. The adjustable position, grid and shape of the array of sensors and the continuous logging of the gravimeters will provide imaging of gravity changes, associated with variations in subsurface fluid properties, with unparalleled spatio-temporal resolution. Specific work will be carried out to ruggedize the devices for field operation. We will deploy the new gravity imager at Etna volcano (Italy), where frequent gravity fluctuations, easy access to the active structures and the presence of a multiparameter monitoring system (including traditional gravimeters) ensure an excellent natural laboratory for testing the new tools. Insights from the new gravity imager will be used for volcanic hazards analysis, to demonstrate the importance of gravity to problems of societal relevance. A successful implementation of NEWTON-g will open new doors for geophysical exploration and will shift the locus of gravimeter manufacture from North America to Europe.

Keywords: gravimetry,mems technology,quantum technology,quantum sensinggeophysics,volcanology,mt etna,subsurface imaging
Resonant-Cavity-Enhanced Organic Photo-detectors and Photovoltaics (RCE-OPP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-04-01
End date: 2022-03-31
Duration (months): 24.0
Total project cost (EUR): 178320.0
EU funding (EUR): 178320.0
Participants: 1
Project status: CLOSED

Organic photo-detecting devices (OPDs) and solar cells (OSCs) both rely on thin films containing blends of electron donors and acceptors, sandwiched between transmissive and reflective electrodes. This project aims to significantly enhance the performance of such devices, by understanding and manipulating resonant optical cavity effects implemented in this simple device architecture. By tuning the cavity resonance wavelength within the optical gap of both donor and acceptor, weak absorption of intermolecular charge transfer (CT) states is significantly enhanced, opening up opportunities to extend the absorption window to longer wavelengths. Using recently reported new non-fullerene acceptors, we will fabricate and characterize wavelength selective resonant cavity enhanced OPDs with high external quantum efficiencies and short response times, operating at longer wavelengths (>1200 nm) than the current state-of-the-art OPDs. To improve OSC performance, we will tune the cavity resonance wavelength to the optical absorption peak wavelength of either the strongly absorbing donor or acceptor. This results in strong light-matter effects causing a redshift of the absorption onset. This approach will be exploited to overcome the rather large voltage losses and optical absorption losses in state-of-the-art OSC devices.

Keywords: organic photodetector,organic solar cells,photon management,optical cavity,voltage loss,nonfullerene
Ultra-Lightweight Concrete for 3D printing technologies (Ultra-LightCon-3D)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-07-01
End date: 2021-06-30
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: CLOSED

The construction industry does not follow the same enlightened path as other fields of science and has thus suffered a technology bypass, relying on centuries-old processes and procedures to manage complex modern projects. In conventional concrete construction projects, more than 60% of the total cost is spent on the formwork. One of the technologies which can revolutionize our perception and approach to construction, is 3D printing of concrete. 3D printing, also referred to as Additive Manufacturing (AM), is a technology which builds solid parts via a layer-by-layer process. Since in 3D printing, no formwork is required, and a short project time is required due to continuous work done by the printer, a dramatic reduction in the project cost and improvement of workers’ safety can be achieved. Up to date, much research has been conducted in the field of printing technique, while design of proper insulation of printed walls has gathered little attention. Although, this issue is highly important due to gradually tightening EU regulations. Therefore, proposed project is aiming to fill the gap in knowledge and introduce for the first-time insulating ultra-lightweight concrete (ULWC) material for AM. By proposed interdisciplinary methodology, based on the experimental and numerical methods, in micro- and macro-scales technology, a multi-scale tool enabling to produce advanced 3D printed wall systems. Multi-scale tool will allow to develop 3D models of ULWCs with optimized mechanical and insulating properties. Hence, limited amount of required field and labor works will be necessary, thus further decrement of the final concrete cost and waste production will be achieved. Through the interdisciplinary approach and establishing industrial cooperation, this project will contribute towards development and production of energy saving constructions in accordance with EU Energy Efficiency Strategy.

Keywords: light weight concrete,3d printing,additive manufacturing,concrete,nanomaterials,micro computed tomography
Solutions for CRitical Raw materials - a European Expert Network (SCRREEN)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Ensuring the sustainable supply of non-energy and non-agricultural raw materials
Action type: Coordination and support actions
Countries involved: Italy,Spain,Germany,Germany,Spain,Italy,Austria,Spain,Spain,Italy,Greece,Sweden,Belgium,Finland,Poland,Slovenia,Sweden,Sweden,Belgium,France,France,France,Netherlands,Netherlands,Netherlands,Japan,Denmark,United Kingdom,United Kingdom
Call: Raw materials policy support actions (H2020-SC5-2016-OneStageB, 2016)
Start date: 2016-11-01
End date: 2019-12-31
Duration (months): 38.0
Total project cost (EUR): 2999500.0
EU funding (EUR): 2999500.0
Participants: 34
Project status: CLOSED

Since the publication of the first list of Critical Raw Materials (CRM) in 2010 by the Ad-hoc Working Group on CRM, numerous European projects have addressed (part of) the CRMs value and several initiatives have contributed to gather (part of) the related community into clusters and associations. This led to the production of important knowledge, unfortunately disseminated. Numerous databases have also been developed, sometimes as duplicates. For the first time in the history, SCRREEN aims at gathering European initiatives, associations, clusters, and projects working on CRMs into along lasting Expert Network on Critical Raw Materials, including the stakeholders, public authorities and civil society representatives. SCRREEN will contribute to improve the CRM strategy in Europe by (i) mapping primary and secondary resources as well as substitutes of CRMs, (ii) estimating the expected demand of various CRMs in the future and identifying major trends, (iii) providing policy and technology recommendations for actions improving the production and the potential substitution of CRM, (iv) addressing specifically WEEE and other EOL products issues related to their mapping and treatment standardization and (vi) identifying the knowledge gained over the last years and easing the access to these data beyond the project. The project consortium also acknowledges the challenges posed by the disruptions required to devlop new CRM strategies, which is why stakeholder dialogue is at the core of SCRREEN: policy, society, R&D and industrial decision-makers are involved to facilitate strategic knowledge-based decisions making to be carried out by these groups. A specific attention will also be brought on informing the general public on our strong dependence on imported raw materials, on the need to replace rare materials with substitutes and on the need to set up innovative and clean actions for exploration, extraction, processing and recycling.

Keywords: critical raw materials
PROVIDING SECURED MOBILE ACCESS SOLUTIONS THROUGH VISIBLE LIGHT COMMUNICATION (LIGHTKEY)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-11-01
End date: 2019-06-30
Duration (months): 32.0
Total project cost (EUR): 1275342.5
EU funding (EUR): 892739.75
Participants: 1
Project status: CLOSED

Mobile access is becoming commonplace: the user gets access to a facility by sending a request to an electronic lock. The lock recognises the request, verifies the provided access code and opens up. Current radio frequency-based communication technologies such as Wi-Fi, near-field communication (NFC), and Bluetooth are applied in a large variety of applications. However, they have serious security drawbacks: the data can be picked up by devices within a 10 metre radius, they are susceptible to hackers, consume large amounts of power, are not interoperable with all operators and platforms and usually require costly hardware. With our Visible Light Communication solution LightKey, we can provide secure mobile access through photonics without any of the drawbacks of currently available mobile access solutions. It can be used on any mobile device as mobile phones already have the required hardware component (LED in the mobile´s flashlight). There are three steps: 1) download and activate LightKey to mobile phone, 2) introduce personal code and 3) LightKey triggers the camera flash or screen light and modulates and optical custom code. For instance: https://www.youtube.com/watch?v=t8y1MLSqrr0 We have the advantage that the global market for Visible Light Communication is about to explode: global annual revenues are predicted to increase from $268 Million in 2014 to $113 Billion by 2022 (CAGR of 126%), as a result of advances in the technology as well as the wide-spread and low-cost application potential. Our revenue model is based on the sales of optical receivers for the receiving locks and doors at around €120 per unit (locks, health). The execution of the LightKey project will allow us to enter the market faster. Based on a discount rate of 25% the NPV is estimated at €7,314,100, and the payback period will be shortened to 2 years. Our mission is to be supported by the EC in order to reduce “time-to-market” as much as possible.

Keywords: visible light communications,electronic security access control solution,mobile devices,security
PORT-Cities: Integrating Sustainability (PORTIS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Innovation actions
Countries involved: Italy,Italy,Germany,Austria,Romania,China,Belgium,Belgium,Romania,Belgium,Lithuania,Belgium,Belgium,Lithuania,United Kingdom,United Kingdom
Call: Demonstrating and testing innovative solutions for cleaner and better urban transport and mobility (H2020-MG-2015_TwoStages, 2015)
Start date: 2016-09-01
End date: 2020-11-30
Duration (months): 51.0
Total project cost (EUR): 17678400.0
EU funding (EUR): 16376774.63
Participants: 34
Project status: CLOSED

Port Cities can be seen as multidimensional laboratories where challenges connected with urban mobility are more complex due to the dual system of gravity centre: the city, the port, not to mention their shared hinterland.These peculiarities are at once a challenge and an opportunity, as they provide scope for planning, researching and implementing integrated mobility solutions in distinctively complex urban contexts. Civitas PORTIS designs, demonstrates and evaluates integrated sets of sustainable mobility measures in 5 major port cities located on the North Sea (Aberdeen and Antwerp), the Mediterranean Sea (Trieste), the Black Sea (Constanta), and Baltic Sea (Klaipeda). The project also involves a major international follower port city on the East China Sea (Ningbo). Thanks to the Civitas Initiative, the partner cities expect to prove that more efficient and sustainable mobility is conducive to the establishment of vital and multi-modal hubs for urban, regional, national and International movements of passengers and goods. To do this, they establish integrated living laboratories clustering local measures according to four major aspects of sustainable urban mobility: 1. Governance: to increase port-city collaborative planning and participation, leading to enhanced forms of SUMPs. 2. People: to foster less car-dependent mobility styles, leading to modal shift in favour of collective and more active transport. 3. Transport system: to strengthen the efficiency of road traffic management to/from the port and through the city, and foster the use of clean vehicles. 4. Goods: to enhance logistics and freight transport, improving the efficiency and coordination of city, port and regional freight movements. Working with port cities, Civitas PORTIS will generate a strong and twofold replication potential: 1) specifically to other port cities, and 2) more generally to cities presenting major transport nodes and attractors for the benefit of the whole CIVITAS Initiative.

Keywords: governance and co planning,integrated sumps,urban logistics,reallocation of road space,car independent lifestyle