Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Interoperable, Scalable and seCure Ac-Dc modular Automation system (InterSCADA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Germany,Italy,Ireland,Spain,Greece,Poland,Slovenia,Norway,France,Taiwan, Province of China
Call: Development and integration of advanced software tools in SCADA systems for High, Medium and Low voltage AC/DC hybrid systems (HORIZON-CL5-2024-D3-01, 2024)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 6747767.5
EU funding (EUR): 5999844.25
Participants: 18
Project status: SIGNED

The ongoing transformation of the European energy sector is crucial to reduce CO2 emissions and increase security of supply and independence from energy imports. A pillar of this transformation is increased power generation from renewable resources, especially wind power and photovoltaics, but also electrification of the heating and mobility sector. These generators and consumers of electrical energy are increasingly connected to the power grid via power electronic converters. Furthermore, DC lines and subnetworks are built to reduce power conversion losses and achieve cost-efficient network strengthening. Due to these trends, power systems are increasingly hybrid AC/DC systems, and their dynamic is highly influenced by power electronic devices. Maintaining system stability and situation awareness in such hybrid systems is a challenge for system operators on distribution and transmission level and creates a need for SCADA systems that are adaptable and help operators to tackle the challenges posed by the rapid transformation of the grids. InterSCADA is committed to developing and providing an open-source, vendor-independent SCADA system for operators. This will enable them to quickly adapt to sudden system perturbations, implement new monitoring and control functions, and maintain situational awareness. The InterSCADA platform will implement a set of relevant functions as microservices, creating a modular SCADA system for system operators. The InterSCADA solutions will be deployed and tested in demonstration sites in four different countries, involving both distribution and transmission system operators. Furthermore, InterSCADA will provide recommendations to grid codes and standards for hybrid AC/DC systems, aiming to facilitate the transformation of the power grid while ensuring the maintenance of stability and reliability.
Symphera: Revolutionizing laparoscopic surgery through automated in-body tool switching (Symphera)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open 2025 (HORIZON-EIC-2025-ACCELERATOR-02, 2025)
Start date: 2025-11-01
End date: 2027-10-31
Duration (months): 24.0
Total project cost (EUR): 3561000.0
EU funding (EUR): 2492700.0
Participants: 1
Project status: SIGNED

Laparoscopic surgery, performed >15M/year, is a cornerstone of modern care, offering benefits like faster recovery, reduced pain, & lower infection risks. However, frequent manual instrument changes (20–50/procedure) create critical inefficiencies, consuming 22% of surgery time, adding as much as 20 to 40 minutes to operations, & costing healthcare systems >€16Bn/year in preventable costs. These disruptions force surgeons to break focus, increasing errors, delaying emergency responses, & contributing to longer surgeries, higher complication rates, & poorer patient outcomes. For healthcare providers, these inefficiencies escalate operating room (OR) costs, reduce patient access, & hinder workflow optimization. Patients face increased risks of infections, tissue damage, & prolonged recovery times. We address these challenges with the Symphera System, an innovative laparoscopic surgery solution featuring automated in-body instrument switching. Like a multipen, it transitions seamlessly between up to eight instrument tips in ≤3 seconds, eliminating 85% of instrument change time. This reduces workflow disruptions, allowing surgeons to complete 80% of procedure time with the system, recover 15 to 30 minutes of OR time per surgery, & cut costs by between €750 to €1,500/procedure. The system preserves tactile feedback for precision & provides data for surgical insights that optimize training, protocols, & patient outcomes. By addressing €16B in inefficiencies, Symphera streamlines surgical workflows & improves resource utilization. To bring the Symphera System to market, we aim to complete in-human trials to validate safety & efficacy, secure FDA 510(k) & CE certification (class IIb). This will involve testing in simulated operating environments, design finalization, scalable GMP-compliant manufacturing, & regulatory submissions supported by robust clinical data. Scaling will focus on expanding production, enhancing device functionality & a PMCF to generate real-world data

Keywords: laparoscopic surgery,automated tool switching,multifunctional surgery device
Development and Clinical Evaluation of an Automated Laparoscopic Instrument Stabiliser (ALIS) (ALIS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Smart Surgical Appliances (SSA) is revolutionizing the field of minimally invasive surgery (MIS) with its groundbreaking innovation, the Automated Laparoscopic Instrument Stabilizer (ALIS). This pioneering, on-patient robotic system allows surgeons to perform solo surgeries, addressing critical inefficiencies and barriers in traditional laparoscopic and robotic techniques. Controlled using sensorized surgical shoes, ALIS eliminates the need for a human assistant, providing surgeons with precise, hands-free control of the laparoscope. This innovation reduces procedure times, enhances surgical precision, and optimizes healthcare resources. ALIS is poised to disrupt a rapidly growing market, with the global laparoscopy devices market expected to grow from $8.3 billion in 2024 to $12.52 billion by 2030. Its potential extends to addressing key challenges in healthcare systems, such as lengthy patient waiting lists and high procedural costs. The project aligns with global sustainability goals, incorporating recyclable materials and minimizing waste, thereby contributing to a circular economy. The phased rollout strategy ensures rigorous validation, optimizing each product phase—from the innovative trocar to the ALIS system—before market introduction. SSA’s multidisciplinary team, comprising experts in surgical technology, engineering, and regulatory compliance, underpins the development and commercialization of ALIS. To advance ALIS from TRL 6 to TRL 7-8, SSA seeks €1.5 million, which will support personnel, technology development, regulatory compliance, and operational costs. This funding will catalyze SSA’s mission to redefine MIS, delivering transformative impacts on healthcare efficiency, patient outcomes, and resource utilization. By bridging technological innovation with practical application, SSA is creating a scalable, sustainable solution that positions it at the forefront of surgical robotics, ready to meet the needs of a post-pandemic healthcare landscape.

Keywords: minimally invasive surgery,endosurgery,laparoscopic surgery,surgical robotics
A scalable and optimised platform for microgravity research and the return of useful charges (BentoBox)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Luxembourg
Call: EIC Accelerator Open 2025 (HORIZON-EIC-2025-ACCELERATOR-02, 2025)
Start date: 2025-11-01
End date: 2027-10-31
Duration (months): 24.0
Total project cost (EUR): 3540000.0
EU funding (EUR): 2478000.0
Participants: 1
Project status: SIGNED

Fostered by the New Space dynamic, the technological advances and falling operational costs of next-generation launch systems, Space Cargo Unlimited (SCU) is leveraing the potential for space-microgravity research and manufacturing in Low Earth Orbit. The BentoBox aims to democratize access to microgravity environments, making space-based research and manufacturing more accessible and affordable for a wide range of customers. By leveraging its innovative technology and strategic partnerships, SCU is poised to lead the next industrial revolution in space manufacturing. Its approach is based on three key principles. Firstly, to reduce the requirements on payloads that are too specific to the space environment. Secondly, to move from asynchronous operations to near real-time monitoring. And finally, to ensure durability through a maximum reusability of our hardware. Key features of the BentoBox includes: • Flexible launch options with frequent missions, modular pricing based on mass, volume and optional services such as power supply, thermal control and real-time telemetry; • Optimized infrastructure for experimentation and manufacturing in microgravity, with sample return capabilities; • Simplified access to space for public and private organizations, reducing costs by eliminating manned flight constraints and simplifying certification procedures; • Easier integration, with optimised management of the payload environment (temperature, electrical power, pressure, vibrations) • Automated platform enabling rapid assignments every six months, adapted to research cycles as well as commercial cycles. The purpose of the EIC Accelerator project is to finalize the development of the BentoBox through an increase of its payload acceptance (mass and volume) until fall 2027 for it to accomodate all use cases and scale up SCU's service capacities

Keywords: space as a service,microgravity,space based research and manufacturing,unmanned platform,low earth orbit,new space
Next generation cybersecurity solution for defence against advanced cyber attacks (GRYPHON)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Slovakia
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499999.0
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

IstroSec, a cybersecurity firm founded in Slovakia in 2021, is actively seeking funding from the European Innovation Council (EIC) to advance its cutting-edge ransomware protection solution, Gryphon. Leveraging an innovative dual-purpose security approach, combining proactive and reactive measures with behavioural detection, Gryphon has achieved a remarkable 100% detection rate in testing environments. What sets Gryphon apart is its unparalleled capability to identify malicious intent within network behavioral patterns, providing robust protection against both known and unknown threats. Gryphon is the initial solution of Istrosec's ambition to develop a next generation cyber security technology. Already proven effective with existing clients, including critical infrastructure entities, Gryphon has demonstrated its efficacy, paving the way for further development and market expansion. Given the alarming rise of ransomware attacks, which reached a staggering 493.33 million in 2022, the need for advanced cybersecurity solutions is more pressing than ever. Projected ransomware damages are expected to surpass EUR 27 billion in 2023, with a rapid escalation to EUR 240 billion by 2031. Many ransomware attacks go undisclosed, and the true costs remain covered. Our team, composed of experienced leaders with extensive backgrounds in high-level security, envisions Gryphon as a cost-efficient and reliable solution to meet the evolving challenges of cybersecurity. The proposal systematically introduces Gryphon's superiority over existing solutions, addresses market weaknesses, and underscores the increasing demand for a disruptive cybersecurity approach that effectively combats unknown (zero-day) and advanced threats.

Keywords: behavioural analysis ransomware next generation antivirus endpoint detection and response extended detection and response
Memory and Archive Ontology in Digitalization of War Heritage in the Western Balkans (MARCH-ON-DIGIT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 230184.72
EU funding (EUR): 230184.72
Participants: 1
Project status: SIGNED

"Memory and Archive Ontology in Digitalization of War Heritage in the Western Balkans" (MARCH-ON-DIGIT) project aims to investigate the intersection of memory and archive in the context of digitalization, focusing on the 20th century war heritage in the Western Balkans (WB). The project examines this ontological relation through the lens of institutionalized remembering within WB memory institutions, such are libraries, archives, and museums. By addressing it the project offers a fresh perspective on the impact of digitalization on memory preservation and transmission. It will be conducted at the Centre for Southeast European Studies, University of Graz, by an experienced researcher in digital humanities and cultural studies, in collaboration with a team of established experts in history, international relations, digital research methods and technologies. The project proposes a groundbreaking exploration of the intricate ontology between Europeanization processes, memory, and archive in the context of digitalization and preservation of digital heritage. It aims to unravel the complex influence of heritage digitalization on remembrance practices in the digital age. MARCH-ON-DIGIT addresses a critical gap in the scientific community's understanding of digital heritage preservation related to conflicts. The project's innovation is also amplified by its focus on the WB region, where a turbulent history of recent conflicts profoundly shapes current political and historical narratives. This research is particularly relevant and timely as the region nominally strives for transnational unity within the processes of Europeanization, but progress lacks which creates internal tensions, which this project will evaluate from the cultural memory and digital heritage theoretical approaches. By critically investigating this topic from both national and international perspectives, the project will serve as a pioneering reference for similar research in the broader European context.

Keywords: digital heritage preservation,europeanization,western balkans
Circular and Bio-Based Solutions for the Ultimate Prevention of Plastics in Rivers Integrated with Elimination And Monitoring Technologies (UPSTREAM)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Ocean, seas and waters
Destination: Ocean, seas and waters
Action type: Innovation actions
Countries involved: Spain,France,Italy,United Kingdom,Belgium,Slovenia,Portugal,Serbia,Greece,Germany,Netherlands
Call: Prevent and eliminate litter, plastics and microplastics: Innovative solutions for waste-free European rivers (HORIZON-MISS-2022-OCEAN-01, 2022)
Start date: 2023-09-01
End date: 2027-08-31
Duration (months): 48.0
Total project cost (EUR): 7958026.65
EU funding (EUR): 7024032.9
Participants: 22
Project status: SIGNED

UPSTREAM addresses the targets of the Mission by overcoming challenges related to the monitoring, prevention, elimination, and valorisation of litter (L), plastics (P), and microplastics (MP). Demonstrating a suite of 14 solutions addressing pollution at every step in the water system, connected to 7 rivers in 5 countries, will enable the co-creation of an extensive database of knowledge and sustainable business models with a focus on making information as widely accessible as possible. The involvement of wastewater treatment plant (WWTP) owners, industrial partners with existing supply chains, innovative SMEs, and a water cluster association will ensure exploitation of the project solutions, while €500k in cascade funding will enhance replication across Europe. The UPSTREAM consortium will thus establish circular value chains with the potential to decrease plastic litter by 50% and MP pollution by 30%. The advances in UPSTREAM are based on best-in-world innovations, including: • Standardised, rapid monitoring techniques able to detect MP down to sizes >25 μm • Bio-based, biodegradable plastics the stop the formation of MP in consumer products and WWTPs themselves • Elimination of more than 90% MP within WWTPs from both sludge and effluent streams • Innovative floating platforms capable of removing >83% of L, P, and MP directly from rivers at both the surface and riverbed, without creating noise pollution or harming ecosystems • Production of relevant monomers from recovered plastics through both advanced fractionation and depolymerisation and biotransformation UPSTREAM represents a pan-European consortium with 5 demo sites across Europe, including 4 WWTPs (UK, ES, DE, IT), plus a testing area on the Danube in Serbia. The consortium is strengthened by top European RTOs, the world leader in sustainable bioplastics development, Novamont, and completed by partners dedicated to creating a digital knowledge sharing platform and engaging with citizens and stakeholders.

Keywords: bioplastics,drones,fluorescent dyeing,advanced oxidation process,daphnia waterfleas,membranes,pha,depolymerisation,cellulose,wastewater treatment
Regulation of gene dosage on the mouse X chromosome (REGULADOSIX)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative B iology : from Genes and Genomes to S ystems
Panel description: For all organis ms: Genetics, epigenetics, genomics  and other ‘omics studies , bioinformatics, systems biology , genetic diseases , gene editing, innovative methods and modelling,  ‘omics for personalised  medicine
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1954154.0
EU funding (EUR): 1954154.0
Participants: 3
Project status: SIGNED

Differences in gene dosage can be as powerful as to drive species evolution (e.g., whole-genome duplications) and as harmful as to lead to human diseases (e.g., aneuploidies or haploinsufficiencies). Regulating the effects of gene-dosage differences is thus extremely critical, and this is paradigmatically illustrated by what happens to the X chromosome in mammals. In XX individuals, one of the X chromosomes is transcriptionally silenced as a result of a developmental and epigenetic process called X-chromosome inactivation (XCI), which is presumed to have evolved to compensate X-linked gene dosage between XX and XY individuals. Since its ‘discovery’ in 1961 by Mary Lyon, we have learnt much about XCI developmental dynamics and molecular underpinnings, however very little is understood about the developmental and molecular reasons at the basis of its evolution. REGULADOSIX aims to gain a functional and mechanistic understanding of the need of X-linked dosage compensation in mammals – we will (i) determine the developmental and molecular consequences in the absence of XCI in mouse embryogenesis, and (ii) functionally identify genes on the X chromosome that are dosage-sensitive, as well as their functions, which would have dictated the emergence of XCI in mammalian evolution. Building on my previous expertise, I propose a multidisciplinary approach at the intersection between development and genetic engineering, which includes cutting-edge genomic technologies (epigenetic screens, functional transcriptomics and proteomics) and novel approaches that we will develop to tune levels of expression in mouse embryonic stem cells and in mouse models. Besides bringing new insights into the need for dosage compensation between the mammalian sexes, REGULADOSIX will contribute to a quantitative understanding of gene expression, and pave the way to establishing fundamental principles of gene dosage regulation in development and disease.

Keywords: x chromosome inactivation dosage compensation gene dosage dosage sensitivity mouse embryonic stem cells
noVEl appRoaches to the quantuM bOUnds To cHaos (VERMOUTH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France,United States
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 3
Project status: CLOSED

The recent technological and experimental advances in the field of quantum simulation and computation have led to the renaissance of the study of the dynamics of complex quantum systems. Different interdisciplinary approaches, merging concepts from condensed matter, high energy physics and quantum information, have emphasised the existence of constraints given by quantum mechanics on the time evolution of correlations and the transport properties. The purpose of this proposal is to tackle several outstanding issues at the intersection of these fields from the perspective of standard quantum statistical mechanics. The project integrates the Applicant's expertise in quantum many-body dynamics with the Host broad experience in statistical mechanics, taking full advantage of the unique multidisciplinary environment provided by the hosting institution. The research will be carried out in the perfectly suited environment of the Statistical Physics group at the Laboratoire de Physique de l'Ecole Normale Superieure with Prof. J. Kurchan.

Keywords: quantum chaos,quantum information,scrambling,quantum lyapunov exponents,syk model,planckian bounds