Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
AIDA: Allergy Immunotherapy based on Designed Allergens (AIDA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2023-04-01
End date: 2024-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Allergy is a severe immune reaction to foreign substances known as allergens, with respiratory and food allergies affecting 30% and 10% of the global population, respectively. A high structural similarity exists between pollen and food allergens. Therefore, many people suffer from both types of allergies. Untreated allergies have detrimental effects on health-related quality of life, family economics, and work attendance. Allergy is treated as a chronic disease, with a focus on reducing symptoms (e.g., antihistamines), which is cumbersome and expensive. The only existing curative treatment, allergen immunotherapy (AIT), consists of up to 5 years of monthly exposure to low amounts of the triggering allergen until the immune system is desensitized. Unfortunately, this approach is costly for healthcare providers and its efficacy varies, being especially low for patients allergic to multiple pollen and foodstuff sources. Only 40% of patients choose to undergo AIT, and 20% of these terminate the treatment early due to strong side effects or lack of efficacy. We propose the development of an urgently needed AIT by treating several allergies at once, achieving tolerance faster, and reducing side effects.
Intermediate temperature catalytic methane splitting for a swift energy decarbonization (ZeroCarb)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain,Portugal,Italy
Call: Transition Open 2024 (HORIZON-EIC-2024-TRANSITION-01, 2024)
Start date: 2025-04-01
End date: 2027-09-30
Duration (months): 30.0
Total project cost (EUR): 3138580.38
EU funding (EUR): 2476872.59
Participants: 5
Project status: SIGNED

Project ZeroCarb will develop, optimize, and operate an intermediate-temperature catalytic methane splitting (IT-CMS) reactor, with the balance of plant, in a relevant environment (TRL6), using biomethane as feedstock and green electricity. This project follows 112CO2 (GA 952219), which developed the fundamentals for the IT-CMS. It is generally accepted that this reaction, also known as methane decomposition or pyrolysis, will play a critical role in the swift and cost-effective energy transition. Due to this great potential, several different processes have been proposed, and new and existing companies are investing in this technology. IT-CMS technology displays, however, critical advantages over all other technologies: i) avoids the use of special reactor’s envelop materials, since it runs at 750 °C and 1 bar, and is catalytic; ii) when fed with biomethane it produces H2 with a negative CO2 footprint and renewable graphitic carbon; iii) the produced metal-free carbon nanofilaments (mostly MWCNT) are shaved off chemically using H2; iv) the reactor is more energy efficient since it uses a fixed bed; v) the catalyst is activated steel foil, commercially available, which reduces the CAPEX tremendously; vi) the reactor module is expected to display a high power density, ca. 1.5 kW L-1, and energy efficiency > 80 %, and a catalyst high stability >> 8500 h; and vii) low CAPEX plant, significantly cheaper than an SMR plant. ZeroCarb targets the development of a demonstration unit producing 2 kgH2 h-1 (ca. 67 kWH2e) and 6 kgC h-1, based on an activated steel foil packed in a plate and frame module. HyCarb aims to bring this technology into the market and meet industry standards or regulations. The business model will be validated with the two industrial partners, CapWatt for hydrogen exploitation (for refineries and synthesis of ammonia/methanol) and BeDimensional as an off-taker of high-purity carbon (for electrically conductive inks/pastes and electrochemical devices).

Keywords: intermediate temperature catalytic biomethane splitting methane decomposition,pyrolysis,or cracking graphitic carbon and dispatchable h2 from a renewable source atmospheric co2 to carbon
flight demonstration of a Liquid HYdrogen load-bearing tank in an unmanned cargo platform (fLHYing tank)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Aviation
Action type: Innovation actions
Partnership: CLEAN-AVIATION (JU-JTI)
Countries involved: Slovenia,Austria,Greece,Belgium
Call: Near Term Disruptive Technologies for Hydrogen-Powered Aircraft (HORIZON-JU-Clean-Aviation-2022-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 3947691.25
EU funding (EUR): 2998491.25
Participants: 6
Project status: TERMINATED

The fLHYing tank project aims to flight-test a 1,000-liter flight-load-bearing vacuum-insulated composite LH2 tank in the Pipistrel Nuuva V300 cargo UAV. This project proposal is disruptive in several perspectives: (i) definition of requirements, design, manufacturing and qualification of a relevant-scale flight-load-bearing fully composite liquid hydrogen tank, (ii) accelerated acquisition of knowledge via flight-testing low-TRL hazardous technologies using UAVs, and (iii) effective application of the knowledge via calibration of a fluid-dynamic, thermal and structural digital twin of a composite LH2 tank using flight test data for advancement towards digitalized certification of aeronautical technologies. The fLHYing tank project covers the disruptive maturation of lightweight liquid hydrogen storage systems via the accelerated acquisition of knowledge on flight operation of LH2 tanks, as required by the demonstrator strategy of the Clean Aviation Strategic Research and Innovation Agenda. The main impact of the fLHYing tank project is the unprecedented reduction in the time-to-market of revolutionary technologies in the aeronautical industry, thanks to the ground-breaking fast-track flight testing of a relevant-scale composite LH2 storage system using a UAV, achieving comprehensive understanding of the behaviour of LH2 tanks in the flight environment within minimum timeframe, risk, and cost. This ambitious goal can be achieved within the 1st phase of the Clean Aviation Programme thanks to the fLHYing tank project.

Keywords: liquid hydrogen,composite,material screening,flight load bearing tank,hydrogen peripherals,ground qualification,flight testing,uav,digital twin,validation
Affect, Form and Matter in 17th-Century Lyric Poetry (AFM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 1
Project status: SIGNED

This research project on Affect, Form and Matter in 17th-Century Lyric Poetry (AFM) aims to trace the formal, material and textu(r)al entanglements of affect in English metaphysical poetry and to find a new methodology of reading (for) affect in literary texts. The project’s fundamental claims are that (1) affect is entangled in a text’s form, materiality and cultural-historical contexts and that (2) it is a constitutive element of metaphysical poetry and accounts for the particularities of this style of early modern writing. To come to terms with affect’s complex textual entanglements, a new methodology, tentatively called “differential reading,” will be developed. Differential reading is an integrative method that combines approaches from affect studies, new formalism, new materialism and cognitive studies but also pays heed to the cultural-historical contexts of production and reception that impact on a text’s affectivity. Differential reading will serve as the central approach to metaphysical poetry as well as to poetry by 17th-century women writers who are not typically classified as ‘metaphysical,’ but whose poems show similar affective-stylistic entanglements. The project will result in differential readings of a range of 17th-century poems that will show the centrality of affects to the metaphysical style. Poetic affect will be traced across different modes and motifs that are both key to metaphysical poetry and to the experience of affect, namely seeing and hearing as sensory modes of affective encounter; time and space as affectively inflected modes of perception and orientation; and material objects as cultural-historical sites of affective encounters. Finally, the project will also consider how these poems metapoetically reflect their own engagement with affect. The project’s results will be of use not only for the field of early modern literature, but for researchers in literature and affect and in the wider field of affect studies alike.

Keywords: affect studies,metaphysical poetry,early modern literature,new formalism,new materialism,textual performativity,lyric poetry
Microcomb Photonic Engine (M-Engine)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Challenges
Action type: EIC actions
Countries involved: Ireland,Germany,France,Switzerland
Call: EIC Transition Challenge: Chip-scale optical frequency combs (HORIZON-EIC-2023-TRANSITION-01, 2023)
Start date: 2023-12-01
End date: 2026-11-30
Duration (months): 36.0
Total project cost (EUR): 2499445.93
EU funding (EUR): 2499445.93
Participants: 6
Project status: SIGNED

M-ENGINE proposes a unique solution to the rapidly increasing bandwidth demands of data centers. With the massive growth of AI and social media in an increasingly connected world, data centers are expected to account for 20% of Europe's energy use by 2030, posing a significant challenge to meet the EU's climate goals. Current solutions to increase bandwidth in optical communications involve adding more single-channel lasers, which neither meets the capacity needs nor the energy requirements. Our proposal offers a scalable solution based on the Nobel prize-winning technology of optical frequency combs to provide highly coherent multi-channel lasers for high-capacity, low energy consumption data transmission. M-ENGINE's solution can replace 100s of individual lasers used in connecting data centers with just one compact system. The proposal combines Enlightra's photonic chip technology with X-Celeprint's cutting-edge solution of micro-transfer printing for scalable heterogeneous integration of all necessary photonic and electronic components. Eblana photonics’ high-power distributed feedback lasers will be transformed for transfer printing on the wafer scale, while Deutsches Elektronen-Synchrotron (DESY) and Laboratoire Interdisciplinaire Carnot de Bourgogne (ICB) will contribute recent breakthroughs in chip-integrated frequency combs enabling increased efficiency, stability, and equalized power of the generated data channels. Dublin City University (DCU) will perform independent performance testing for telecom before test devices are sent out to customers for pilot projects. The result will be a scalable photonic chip engine meeting future data needs with reliability, long-term operation, and a clear business case. M-ENGINE's primary market focus will be data centers, but it will have the flexibility to address related markets, such as photonic computing. The consortium aims to create a viable solution in 5 years when the market is expected to be valued at €14Bn.

Keywords: optical frequency combs,microresonators,silicon nitride
Highly sensitive, high spatial resolution, high throughput and full elemental mapping: simultaneous fs-ns DP-LIBS/LA-ICPMS (HSPTFE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: CLOSED

Multi-elemental mapping, allowing the characterization of the elemental distribution in heterogeneous samples at high spatial resolution (~µm scale), are opening new applications in many fields. As two laser ablation-based techniques, laser induced breakdown spectroscopy (LIBS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS), are becoming more and more attractive, due to the advantages such as rapid, sensitive, and high spatial resolution mapping. Especially, they are complementary to each other, where LA-ICPMS offers more sensitive analysis while LIBS can analyze the elements that are difficult or impossible for LA-ICPMS analysis, such as H, O, N, C, or halogens. Full elemental fast mapping applications can be achieved with simultaneous LIBS-LAICPMS technique. However, due to the different detection mechanisms for these two techniques, the optimal laser operation conditions were different, where LIBS typically require higher laser pulse energy than LA-ICPMS. Therefore, the LIBS signal under standard LA-ICPMS conditions are generally relatively low. In this project, to enhance the LIBS signal without significantly affecting ICPMS analysis, combination of double pulse LIBS in an orthogonal configuration and LA-ICPMS is proposed, where a second laser pulse (ns) is used to reheat the plasma plume/aerosol induced by the first laser ablation pulse (fs), to carry out highly sensitive, high spatial resolution, high throughput and full elemental mapping. To perform simultaneous optimal analysis by LIBS and LA-ICPMS, a high-performance ablation cell with optimized optical collection lenses will be designed and developed. Further on, the analytical setup will be established and corresponding analytical methodology for full elemental imaging will be developed and applied for the real samples such as gemstone. The developed DP-LIBS/LA-ICPMS technique is potential for various filed such as biological, mapping, and material sciences.

Keywords: elemental mapping laser ablation libs la icpms
Self-organisation and barrier functions of the mammalian glycocalyx – Training glycoscientists across disciplines and borders to stimulate new approaches, understanding and biomedical applications (GLYCOCALYX)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom,Austria,France,Germany,Portugal,Spain,Sweden
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2025-12-01
End date: 2029-11-30
Duration (months): 48.0
Total project cost (EUR): 5055540.74
EU funding (EUR): 4781679.12
Participants: 18
Project status: SIGNED

Virtually all mammalian cells are covered with a dense and complex coat of sugar chains (glycans) known as the glycocalyx, which is essential for multicellular life. Interfacing the cell surface with the cellular environment, glycocalyces accomplish critical functions in signalling and communication between cells, controlling tissue development, homeostasis and repair, inflammatory and immune responses, neuronal connectivity, and symbiosis with gastrointestinal bacteria. However, when dysregulated, they can promote immune diseases, neurodegeneration and cancer. While glycocalyces act as the first line of defence against pathogens, some pathogens have evolved to hijack the glycocalyx to promote infection. Despite their importance, mammalian glycocalyces remain the ‘dark matter’ of biology, under-studied owing to the historical lack of preparative and analytical tools to probe the local molecular composition and transient interactions of molecules within glycocalyces, and missing physics rules to interpret experimental observations. The GLYCOCALYX Doctoral Network will provide 15 doctoral candidates with training in bespoke physics, chemistry and biology methods – essential disciplines that will be integrated to enable us to resolve the dynamic organisation of glycocalyces, and how they perform the many selective barrier functions essential to multicellular life. We will develop chemical, analytical and computational TOOLS for glycocalyx research and use them to define physics and molecular RULES that underpin glycocalyx self-organisation and barrier functions. Practical scientific training in state-of-the-art research methods will be complemented by a coordinated programme of industry-relevant transferable skills tailored to prepare the doctoral candidates for future careers in the sector of medical technologies and its underpinning innovations.

Keywords: multivalent interactions glycan optical microscopy glycocalyx models perineuronal net mucosal glycocalyx endothelial glycocalyx immune synapse soft matter physics
Harnessing the Giant Orbital Hall effect for mutual synchronization in nano-oscillators (GOHE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-08-01
End date: 2027-07-31
Duration (months): 24.0
Total project cost (EUR): 206887.68
EU funding (EUR): 206887.68
Participants: 1
Project status: SIGNED

Since its initial prediction, the spin Hall effect (SHE) has played a major role in spintronics thanks to its intriguing physics and tremendous potential for applications via the spin currents generated from charge currents. In the last few years, another phenomenon, the so-called orbital Hall effect (OHE), has also emerged. The OHE is the generation of pure orbital currents from the charge current, ushering in the era of orbitronics. The magnitude of the OHE is predicted to be 1-2 orders higher than the SHE, and therefore, it is imperative to harness it for the development of spintronic devices, e.g., to use it to excite auto-oscillations at microwave frequencies. Therefore, the Giant Orbital Hall Effect (GOHE) project aims at using the OHE instead of the SHE in spintronic nano-oscillators, to create a paradigm shift in the designing of next-generation orbitronics-based devices. Here, I propose a systematic study of different combinations of non-magnetic (NM)/heavy metal (HM)/ferromagnetic (FM) based heterostructures to harness the OHE and utilize it for the mutual synchronization of the world’s first orbital Hall nano-oscillators (OHNOs), to serve as a bridge to the already known capacity of spin Hall nano-oscillators (SHNOs) by the host group. Moreover, in this project, I aim to reliably elucidate the explicit contribution of bulk and interfacial OHE, in analogy with its counterpart, SHE. I will also study and unravel the fundamental mechanism OHE by disentangling the intrinsic and extrinsic contribution of scattering from impurities in host, and develop its background in line with SHE.

Keywords: spintronics,spin hall effect,orbital hall effect,spin hall nano oscillators,spin torque ferromagnetic resonance
Syntactic functionality of motion verbs in Italo-Romance (SynFuMIR)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 1
Project status: SIGNED

The project SynFuMIR investigates functionality in syntax by analyzing complex motion verb constructions in regional Italian. Functionality concerns various grammatical aspects of certain linguistic items that allow lexical units to be assembled together in more complex structures. Although it is a fundamental aspect of language, its nature has not been fully understood yet. Crucial questions to theoretical linguistics depend on our understanding of functionality. These questions will be tackled with new data from multilingual speakers. Syntactic functionality will be investigated by collecting new data via on-site fieldwork with speakers of Southern regional Italian, Sicilian, Calabrian, and Apulian (around 300 speakers in total). The considered constructions are restructuring, pseudo-coordination, and multiple agreement constructions. The main objective of the study is the development of a new theory of syntactic functionality based on the role of location as a syntactic element. My hypothesis is that location plays a crucial role in functionality and non-canonical argument structure. Other goals are language documentation and the investigation of language contact. By focusing on language contact between two or more extremely closely related languages that contain slightly different but comparable constructions, the involved grammatical features will be investigated in a new way compared to previous studies on the topic. Our understanding of language contact (micro-contact) and multilingualism (bilectalism) will also benefit from this study. Besides its contribution to grammatical theory, this project has also a social and cultural impact on speakers communities because of the engagement of Italian speakers about their dialects and the acknowledgment of regional Italians as real languages. It also represents an example of fruitful collaboration between different fields of linguistics: theoretical syntax, experimental linguistics, and sociolinguistics.

Keywords: syntax,theoretical linguistics,functionality,motion verbs,multilingualism,dialectology,romance linguistics,italian,cross linguistic variation