Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Multifunctional aIrcraft power network with Solid-State electrIcal pOwer SwitchiNg (MISSION)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Italy,Switzerland,United Kingdom
Call: Multifunctional Aircraft Power Network with Electrical Switching (H2020-CS2-CFP08-2018-01, 2018)
Start date: 2019-06-01
End date: 2022-11-30
Duration (months): 42.0
Total project cost (EUR): 1209287.5
EU funding (EUR): 1116051.25
Participants: 3
Project status: SIGNED

The MISSION Consortium will bring together world-leading expertise in the field of aircraft electric power systems, power line communication systems, solid-state power electronics technologies, metaphysical modelling and simulation, control, validation testing and integration, to design, develop, manufacture and validate the advanced electrical power distribution system (EPDS) based on Multifunctional Power Network with Electrical Switching. This will be a key component in the creation and demonstration of the Multifunctional Fuselage demonstrator being developed within Clean Sky 2 LPA IADP platform 2. The technical areas of work will cover advanced architectures for the Electric Power Systems (EPS) architecture including their design, control and analysis, Power Electronic Switches based on Solid-State Devices, onboard communication networks, power line communication systems, and Power Line Communication (PLC). The technical work will be completed with advanced methods in model-based design, as well as multi-physic modelling and simulation, together with world-recognised expertise in manufacturing, testing and qualification of EPDS for aerospace applications to. This will enable a step changebreakthrough in the design and development of integrated electrical power bus and communication system (IPBCS) for future aircraft platforms. by introducing highly innovative technological solutions leading to a substantial reduction of overall weight, making aircraft more efficient, hence reducing fuel burn and contributing towards more efficient, greener aviation.

Keywords: electrical network,power electronics,electrical system
The Canadian model of the public-private sponsorship for the integration of refugees: the case of Syrians and possible application in EU countries (REFINTEG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Canada
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-10-01
End date: 2022-09-30
Duration (months): 36.0
Total project cost (EUR): 255768.0
EU funding (EUR): 255768.0
Participants: 2
Project status: CLOSED

Since the Syrian civil war began in March 2011, the United Nations High Commissioner for Refugees estimates that more than 13 million people are in need and an estimated 5.6 million Syrians have fled the country. From this group of Syrian refugees, around one million have requested asylum in different countries of the European Union. While in the EU there is a strong debate concerning the recent refugee crisis and the need to completely reform the current asylum system, in Canada the resettlement and integration of refugees has been a considerable success through the implementation of the Private Sponsorship of Refugees Program which has received much attention from policy-makers in other countries over the past decades. The Overall Objective of this project proposal is a comprehensive analyze of the Canadian private sponsorship model to integrate refugees, of its impact in providing to Syrian refugees a safe and legal way to resettlement and socio-economic integration, and an exploration of its possible modalities of application in some countries of the European Union. The researcher will firstly analyze and present, based on a comprehensive review of government documents, existing academic literature and available data, the overall program, and it will describe its benefits, general results and challenges. Subsequently, the researcher will analyze the private sponsorship program impact in the case of Syrian refugees and will compare the outcomes of this model with the outcomes of other programs such as federal government support and Blended Visa Office-Referred (BVOR) program. Then, the researcher will explore the possible application of the Canadian model in some specific EU countries such as Italy and Germany, identifying and discussing possible benefits and challenges, and comparing the results obtained by policies already implemented by these countries with the results of the Canadian model.

Keywords: multiculturalism,interculturalism,intercultural dialogue,human rights
YOUR LIFE. HANDS-ON. (NUADA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Portugal
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-09-01
End date: 2022-09-30
Duration (months): 37.0
Total project cost (EUR): 2456250.0
EU funding (EUR): 1719375.0
Participants: 1
Project status: CLOSED

According to the World Heart Foundation there are 15 million new cases of stroke per year worldwide and 50 million people in the USA suffering from arthritis. Adding to this, repetitive-stress job injuries account for around 30% of doctor diagnosed MSDs. The addressed need represents an immense opportunity to help compensate the disability effects in the function of hand manipulation. The NUADA glove has the potential to be used both as an injury prevention equipment as well as functional support system and even on rehabilitation treatments. Nuada’s solution relies mostly on energy efficient and lightweight components, created to deal with heavy weight support while maintaining touch sensitivity and a non-intrusive relation with the users’ body. With an ergonomic and small design and with an extended life battery, Nuada can be used in everyday life with comfort and discretion. Nuada looks like a simple glove, but if you look closer, it has special built-in tendons that support the hand when required. This is possible by connecting the artificial tendons to a patented, specially designed system that is worn on the users’ wrist. Our glove is lighter, smaller, cheaper and more intelligent and energy efficient than currently available alternatives. The whole system is on the glove and bracelet, not needing battery backpacks. It is also stronger than others, supporting up to 40kg. The most directly competing solutions are electromechanical gloves. They are an emergent market with two players with relatively successful developments so far: SEM glove and NASA/GM. When compared with these currently existing alternatives, NUADA differentiates itself due to having a smaller volume, much smaller energy needs, more support, and a more competitive pricing (about ¼ of the price) that results in much better value-for-money for users.

Keywords: exoskeleton,glove,hand strength,industrial application,ergonomics
Imaging magnetic fields at the nanoscale with a single spin microscope (IMAGINE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: France
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-09-01
End date: 2020-08-31
Duration (months): 60.0
Total project cost (EUR): 1498810.0
EU funding (EUR): 1498810.0
Participants: 1
Project status: CLOSED

Detecting and imaging magnetic fields with high sensitivity and nanoscale resolution is a topic of crucial importance for a wealth of research domains, from material science, to mesoscopic physics, and life sciences. This is obviously also a key requirement for fundamental studies in nanomagnetism and the design of innovative magnetic materials with tailored properties for applications in spintronics. Although a remarkable number of magnetic microscopy techniques have been developed over the last decades, imaging magnetism at the nanoscale remains a challenging task. It was recently realized that the experimental methods allowing for the detection of single spins in the solid-state, which were initially developed for quantum information science, open new avenues for high sensitivity magnetometry. In that spirit, it was recently proposed to use the electronic spin of a single nitrogen-vacancy (NV) defect in diamond as a nanoscale quantum sensor for scanning probe magnetometry. This approach promises significant advances in magnetic imaging since it provides quantitative and vectorial magnetic field measurements, with an unprecedented combination of spatial resolution and magnetic sensitivity, even under ambient conditions. The IMAGINE project intend to exploit the unique performances of scanning-NV magnetometry to achieve major breakthroughs in nanomagnetism. We will first explore the structure of domain walls and individual skyrmions in ultrathin magnetic wires, which both promise disruptive applications in spintronics. This will lead (i) to solve an important academic debate regarding the inner structure of domain walls and (ii) to the first detection of individual skyrmions in ultrathin magnetic wire under ambient conditions. This might result in a new paradigm for spin-based applications in nanoelectronics. We will then explore orbital magnetism in graphene, which has never been observed experimentally and is the purpose of surprising theoretical predictions.

Keywords: single spin physics,nanomagnetism,spintronics
MRI toolkit for in vivo fat virtual biopsy (FatVirtualBiopsy)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Germany
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2020-03-01
End date: 2022-01-31
Duration (months): 23.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

In 2015, four million people worldwide died because of the aftermaths of obesity (7% of total deaths), and in 2030, half of humankind is expected to be overweight. Lifestyle interventions in subjects with obesity can prevent the development of obesity-induced metabolic dysfunction but need personalization in order to become effective for diabetes and cardiovascular disease prevention. Visceral adiposity and adipocyte hypertrophy are phenotypes strongly linked to metabolic dysfunction in subjects with obesity. Visceral adiposity can be non-invasively measured using Magnetic Resonance Imaging (MRI). Adipocyte size measurements are however nowadays only feasible using highly invasive biopsy procedures that cause severe patient discomfort, hold a risk for complications and are therefore rarely performed in the personalization of lifestyle interventions. The ongoing ProFatMRI research program (ERC-StG 677661) focuses on the development of an MRI platform to non-invasively assess fat microstructure. In the present proof of concept (PoC) project, we will translate the lipid droplet size measurement approaches successfully developed within ProFatMRI into an effective and reproducible toolkit (FatVirtualBiopsy) for non-invasive in vivo human adipocyte size measurement. The present PoC project encompasses the evaluation and the technical adjustment of the adipocyte size measurement in the real-life scenario involving a lifestyle intervention in subjects with obesity, the development of a prototype and the adoption of an intellectual property strategy. The PoC project will result in a non-invasive imaging toolkit that can be integrated into clinical prevention, targeting a wide range of medical specialists involved in obesity treatment. FatVirtualBiopsy will therefore contribute to transform the personalization of lifestyle interventions and drastically improve their effectiveness in subjects with obesity towards diabetes and cardiovascular disease prevention.

Keywords: magnetic resonance imaging,obesity,diabetes,personalized prevention
Novel Symbioses (SYMBIOSES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2021-01-01
End date: 2025-12-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The introduction of new functionalities into cells is a challenge, but it offers tremendous opportunities. While some traits may be acquired through lateral gene transfer and be immediately operational, others are complex and require comprehensive rewiring of the host cell due to lack of orthogonality. A powerful strategy used by cells to acquire new properties is the incorporation of other dedicated cells as endosymbionts that may eventually become organelles in the course of evolution, the most prominent example being the origin of the mitochondrion and chloroplast, both of which transformed life as we know it. SYMBIOSES is an interdisciplinary project that will explore endosymbioses in an experimental approach to introduce metabolic traits as cellular compartments. In the first phase of the project, we will (i) design novel cell-in-cell merger couples composed of a unicellular eukaryote as the host and a prokaryote as the designated endosymbiont and use modelling to optimize the metabolic pre-requisites for cooperation and ultimately endosymbioses, (ii) establish cooperating co-cultures of cells that depend on each other metabolically, and (iii) develop nanotechnology approaches to incorporate cells into other cells. In the second phase of the project, we will deliver cells into cells to establish endosymbioses as operating units. We will then optimize endosymbioses by re-engineering and experimental evolution. The approach will unite desired traits consisting of core metabolic processes with a focus on biological nitrogen and carbon fixation. SYMBIOSES will establish know-how and concepts for the introduction of novel compartmentalized functions into organisms and put endosymbioses and ultimately organellogenesis to the test.

Keywords: endosymbiosis,evolution,microbial interaction,metabolism,metabolic engineering,nanotechnology
Exploiting Protein Complexes that Induce Cell-death (EPIC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Iran, Islamic Republic of,Spain,Ireland,Sweden,Belgium
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2015, 2015)
Start date: 2016-01-01
End date: 2019-12-31
Duration (months): 48.0
Total project cost (EUR): 607500.0
EU funding (EUR): 607500.0
Participants: 6
Project status: CLOSED

The formation of specific protein complexes are key events in life-and-death decisions made by cells. Inappropriate decisions underpin a plethora of disease conditions from degenerative diseases to cancer while the role of the complexes in these processes make them important therapeutic targets. Our ability to develop small molecules to target death-inducing protein complexes has been hampered by an inability to measure complex formation in cells in real-time and by the absence of robust high-throughput assays for the discovery of new lead molecules that target these complexes. The proposed network (EPIC) will address both of these problems by developing new approaches to measure necrosome and apoptosome formation in real-time as well as new high-throughput and high-content screening assays using Fluorescence resonance transfer and split-luciferase technologies. EPIC will conform with the H2020 work programme by integrating research activity, novel reagents and expertise across Europe and world through the mobility, knowledge transfer and training of experienced and early stage researchers from within and without the EU. EPIC will realise the potential of researchers through the development of new skill-sets, the transfer new skills between academia and industry, and the development of career opportunities for EU ESRs and ERs. A key part of this activity is the mobility of non-EU researchers and the inward transfer of essential knowledge from outside the EU to benefit EU-based research. Establishment of EPIC through RISE will generate lead molecules with demonstrable utility and knowledge that will underpin applications to national funding agencies to sustain the communal effort beyond the life of the RISE award. It will also generate intellectual property that will enable the network to approach biotech and pharma to form academia-industry partnerships that will further develop small molecule leads as therapeutics.

Keywords: apoptosome,necroptosome,necroptosis,high throughput,screening
New high-performance excipients in pharmaceutical industry: an innovative solution for a more efficient and sustainable drug manufacturing process. (HPE1)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Portugal
Call: Supporting innovative SMEs in the healthcare biotechnology sector (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-12-01
End date: 2017-04-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Pharma73 SA is a Portuguese start-up dedicated to the development, production and commercialization of a new generation of High Functionality Excipients (HFEs). Excipients are inactive ingredients used together with active ingredients to formulate drugs into finished dosage forms. Ranging from 15% to 95% of the total weight of a given drug, excipients are extremely important in terms of procurement, logistics, quality control and final batch release. Pharma73’s technology is based on the production of natural polymers, such as the Chitin Glucan Complex HPE1, obtained from fermentation processes whose unique properties enable their application in a multiplicity of pharmaceutical drugs for oral solid-dosage forms. Adding HPE1 to the final drug formulation will result in better yields and operational savings for the manufacturing industry, thanks to significant functional - physical and chemical properties of the new excipient. Pharma73’s ambition is to introduce a new raw material into the excipient markets, and bring the industry to a new level that better responds to efficiency and sustainability requirements of the drug manufacturing process. Furthermore the innovation related to the adoption of HPE1 will preserve the EU’s competitive advantage over drug manufacturing procedures, creating more job opportunities, and the long-term viability of a European-based pharmaceutical industry. Therefore the commercialization of a novel class of excipients like HPE1 aligns with the EU strategy “Europe 2020 – for a healthier EU”: 1) “Innovation can help make the healthcare sector more sustainable” 2) “the healthcare sector has an important role to play in improving skills and creating jobs as it employs 1 in 10 of the most qualified workers in the EU". The SME instrument will allow Pharma 73 to complete their go-to-market strategy, by demonstrating HPE1 potential for specific drug formulation uses.

Keywords: excipients,binders,fillers,chitin glucan complex,bulk density,drug manufacturing,pharmaceutical,industry,biotechnology,fermentation,purification
Cloudfone Visitor Service - a 'roam like a local' Cloud service for mobile operators (Cloudfone)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Norway
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-06-01
End date: 2016-10-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The increasing trend of people mobility worldwide requires seamless interactions per their mobile phones. International calling-rates and roaming cost of mobile communications set restrictions on exchanges many people would prefer to have for their business and personal communications. IPCO addresses the challenge by offering an open disruptive innovation, specifically by proposing a Cloudfone Visitor Service (CVS) for frequent business travelers, multi-national businesses, foreign workers and long-term tourists. The service idea is generated, owned and patented by IPCO. The service will enable the mobile phone users who are in a foreign country to be recognized as local mobile network customers while keeping the same mobile number from a home country as well as the same SIM card. The implementation of the service eventually would lead to minimization of roaming cost especially for the EU citizens travelling to non-EU countries and vice versa. IPCO Cloudfone Visitor Service (CVS) will be offered as a managed service to Mobile Network Operator (MNO) alliances and multinational Mobile Virtual Network Operators (MVNOs). IPCO ambition for Cloudfone Visitor Service is a coverage in 60 countries with a yearly revenue of 29 M€ and a Net Result of 14 M€ after an initial 5 year ramp up. The main goal of the Cloudfone feasibility study is to verify the proof-of-concept for live demonstrations on mobile infrastructure and standard mobile end-user devices. The objective is to generate interest and commitment of targeted stakeholders and build a customer satisfaction and confidence, while seeking to provide a disruptive innovative solution to the large mobile operators on a global scale.

Keywords: cloud,mobile networks,roam like a local,mobile operators,esim