Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
AGING AND BALANCE CONTROL DURING STAIR AND STEP NEGOTIATION (ABACUSS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands,Australia
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-08-01
End date: 2027-07-31
Duration (months): 36.0
Total project cost (EUR): 270829.44
EU funding (EUR): 270829.44
Participants: 2
Project status: SIGNED

Age-related loss of physical ability and balance control are important predictors for falls in older people. Activities of daily life, such as stair negotiation, are challenging as they require older people to operate close to their functional limits. This makes stair negotiation performance a good candidate to detect early-onset deterioration before a fall occurs, as well as a good task-specific exercise modality. To investigate these assumptions, I will first assess the sensitivity of linear and non-linear analyses of data from body-worn inertial measurement units (IMUs) to detect age-related and training-induced changes in balance control of older people (65+ years). These findings will then be applied to assess improvements of balance control and the underlying changes in neuromuscular organisation following a 1-year home-based stair climbing exercise program in older people. Finally, I aim to elucidate the role of cortical involvement in neuromuscular organisation during stair negotiation in older people using electroencephalograms and analyses of muscle synergies obtain from electromyographic signals of the lower limb muscles. This will allow me to assess the level of cortico-synergy coherence and the plastic changes associated with training-induced adaptations in kinematic profiles during stair negotiation. The findings from this project will contribute to a better understanding of age-related and training-induced adaptations in balance control, neuromuscular organisation, and the role of cortical involvement in task-specific adaptations. In addition, the assessments of sensitivity of current and novel analyses of inertial data will help to improve detection of early-onset deterioration of balance performance to better target training interventions at individuals with increased fall risk.

Keywords: biomechanics
Epigenetic and transcriptional basis of memory engram plasticity (MemoPlasticGenomics)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Denmark
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-08-01
End date: 2027-07-31
Duration (months): 60.0
Total project cost (EUR): 1499948.0
EU funding (EUR): 1499948.0
Participants: 1
Project status: SIGNED

Neuroplasticity underlies learning and memory formation, which allows for accumulation of knowledge. There is an emerging view that a sparse ensemble of neurons, termed as engram cells, represent memory substrate and explain how memory is formed and retrieved. Extensive studies have been carried out to reveal molecular mechanisms regulating structural and synaptic plasticity of memory engram cells. However, there are still fundamental questions remaining to be solved regarding epigenetic and transcriptional basis of recent and remote memory formation, and heterogeneous identity specification of engram cells. To address these issues, I will carry out state-of-the-art genomics/epigenomics analysis of engram cells that are permanently labelled during recent and remote fear memory consolidation. Firstly I will reveal epigenetic and transcriptional mechanisms regulating active-silent state shifts of engram cells during systems memory consolidation in the hippocampus and neocortical regions. Next I will address heterogeneity of engram cells and reveal how a subset of engram cells may become functionally relevant during memory consolidation and retrieval. To particularly address the latter issue, on top of existing sequencing technologies, I will also apply a novel “time machine”-like retrospective whole-genome history tracing approach to obtain molecular profiles of a given timepoint in the past, and overcome the critical limitation of current snapshot-type technologies. To validate relevance of my findings, I will also carry out functional analysis including gene knocking-down and optogenetics approaches. My interdisciplinary research program will shed new light on how environmental cues, including cell-to-cell interaction mediated by neuronal activity and signalling molecules, can be integrated with intrinsic cellular states at the chromatin epigenetic level to regulate neuroplasticity underlying memory engram cell state and/or identity specification.

Keywords: plasticity,learning,memory,engram,neuronal identity,genomics,epigenetics,gene regulation,new sequencing technology
Creativity in Virtual Reality (CREATIVR)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Germany,United States
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 265647.84
EU funding (EUR): 265647.84
Participants: 2
Project status: SIGNED

Recent global developments have significantly accelerated the redefinition of organizational spaces. An increasing number of organizations, particularly those in knowledge-intensive areas, have embraced work models partly localized away from the physical premises of the organization. This is primarily driven by digitalization, pandemic experiences, and increased demands for flexibility from the workforce, indicating a decoupling from fixed physical premises ‘a permanent feature of the future working environment’. This leads to a redefinition of organizational space as encompassing spaces beyond the physical boundaries of the organization. A core characteristic of this redefinition is the increased adoption of digital immersive technologies. Virtual reality (VR) solutions as additions to or even replacements of physical workspaces have accrued increased interest, evident in the rising investments of the last years. While companies start to adopt these technologies, there is little knowledge available on the impact of the use of these technologies on work outcomes.

Keywords: creativity divergent thinking workspace design innovation virtual reality
From light fueled self-oscillators to light communicating material networks (ONLINE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Finland
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-03-01
End date: 2028-02-29
Duration (months): 60.0
Total project cost (EUR): 1495500.0
EU funding (EUR): 1495500.0
Participants: 1
Project status: SIGNED

ONLINE aims to develop new concepts of communication between inanimate materials. What is meant by communication? In biological context, communication refers to interactive behaviour of one organism affecting the current or future behaviour of another. In the context of bioinspired materials, ONLINE will develop life-like material structures that communicate with each other via physical contact, fluidic medium, or optical beams. These inanimate materials will be coupled to form networks that communicate autonomously through light. How to make them? The core concept behind the communicative materials is self-oscillatory (self-sustained) motions in light-responsive liquid crystal elastomers (LCEs). Self-oscillation is a responsive structure that can self-sustain its own mechanical motion in a constant energy field. It captures the key concepts of living organisms, i.e., functioning out of thermodynamic equilibrium and energy dissipation. My goal is to scale down the self-oscillator concepts to the micro-scale and realize soft material robots that can communicate. Why is this important? There exists an increasing need for artificial materials that can interact, alike biological systems. However, all the dynamic features of state-of-the-art responsive materials are based on internal material properties, and making individual materials interact with each other is a huge challenge. ONLINE proposes three new model systems for material communication: (I) Microscopic walker swarm, in which the locomotion and patterns of interactions between individuals can be fully programmed; (II) Cilia array that move cooperatively and self-regulate the fluidics at low Reynolds numbers; (III) Homeostasis-like light-communicating coupled network that provides a full set of tunable parameters to mimic the complexity of biological oscillators.

Keywords: liquid crystal elastomer self sustained oscillation self oscillation micro robot soft robot light driven two photon laser fabrication stimuli responsive materials micro actuator direct laser writing
Quantum Computers for Data Centers (QCDC)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Austria
Call: EIC Accelerator Challenge: Technologies for Open Strategic Autonomy (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-04-01
End date: 2025-03-31
Duration (months): 24.0
Total project cost (EUR): 3656087.5
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

AQT is realizing the first European cloud-accessible quantum computer at internationally competing performance levels. Our two quantum computing setups have been realized within two 19-inch rack cabinets each and are each powered by a single wall-mounted power plug. The hardware is deployed in our data centre and can be installed on-premise at a customer site. The project aims to provide cloud access to AQT's European quantum computers using a novel AQT cloud platform, such that the European quantum ecosystem, in particular our quantum software partners and customers, can thrive without influence or dependence on currently non-EU dominated quantum computing hardware. Our platform infrastructure is meant to be readily extended toward quantum-enabled application services. These future application services will allow us to demonstrate and commercially exploit the advantages of quantum computation in finance, logistics, optimization, materials design, and chemistry.

Keywords: quantum computing
Superstition, Material Religion and Hıdrellez in Turkey (SUPERSTITIOUS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands,Germany,Türkiye
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-01
End date: 2027-07-31
Duration (months): 30.0
Total project cost (EUR): 254330.4
EU funding (EUR): 254330.4
Participants: 3
Project status: SIGNED

This project will investigate the history of Turkey in terms of religion, rather than Islam, to understand the roots of the normative understanding of religiosity as Sunni-Islamic. The aim is to comprehend the “Western” influence on religion and Islam in Turkey and to illuminate the history of material forms of religiosity by focusing on Hıdrellez, a religious practice that was, and still is, celebrated in a convivial manner by people of different ethnic and religious backgrounds. While recent critical approaches in global religious history and material religion aim to overcome any Eurocentrism that still persists in religious studies, the case of Turkey still remains largely unexplored. Situated at the intersection of religious studies and history, this project will break new ground by bringing together a postcolonial history of “superstition” with the historical analysis of “material religion”, and will advance global debates on how religion is discussed today through its critique of essentialist definitions of Muslim majority nations. The research objectives are: (1) to examine the role of “superstition” in the categorisation of Islam during the 1950s as a form of global entanglement between Turkey and the “West”, (2) to investigate the research on the history of religions and “superstitions” as a form of entanglement between Turkey and Germany, (3) to empirically analyse the history of the diversity of religious life by focusing on Hıdrellez, (4) to analyse the transformation of Hıdrellez from a religious practice to Intangible Cultural Heritage. SUPERSTITIOUS will generate international collaborations and foster vibrant cooperation between scientific communities, civil society representatives and citizens. In the early years of the second centenary of the Republic of Türkiye, it intends to lay the foundations for an awareness of religious pluralism and tolerance among its citizens and diaspora communities.

Keywords: superstition,material religion,h drellez,turkey,t rkiye,intangible cultural heritage,khidr,elijah,saint george,convivial religion,shared religious culture
Characterizing Individual Differences in Brain Plasticity and Dynamics to help ensure Effective and Sustainable Health Care (IndiBrain)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands,Portugal,Italy,United Kingdom,Germany,Norway
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-03-01
End date: 2030-02-28
Duration (months): 48.0
Total project cost (EUR): 4776219.41
EU funding (EUR): 4630534.2
Participants: 25
Project status: SIGNED

IndiBrain is a doctorate network designed to provide training in computational neuroscience research, leading to doctoral degrees for 15 doctoral candidates (DCs). The project aims to transform new and existing partnerships of 12 universities into enduring collaborations. Along with contributions from 11 industrial and training partners, our consortium creates the foundation for an European network of highly skilled, resilient, entrepreneurial, and creative neuroscientists. To ensure an innovative training environment for its DCs, the consortium bundles unique European expertise in neuroscience, cutting-edge neuroimaging, along with neurotechnology and computational modeling. Building on experience gained in earlier DNs, IndiBrain’s scientific goal is to advance understanding of individual differences in neuroplasticity and brain dynamics in health and disease using technologies like ultra-high-resolution MRI. The DCs will develop and apply innovative tools for studying the brain, focussing on individual-level biological interpretability, and using vision as a model system. Our training network is a critical step in advancing our understanding of the brain with translation applications in mind for improving diagnosis, treatment, and rehabilitation, ultimately resulting in a better quality of life for individuals with ocular and neurological conditions, as well as healthcare effectiveness and sustainability in the EU and beyond. The network will equip DCs with transferable skills in science communication, collaboration, business development, grant writing, and responsible AI use, improving their career opportunities in research, industry, and as entrepreneurs. They will inspire each other to excel in fundamental and translational research, both during and long after the funding period. Anticipating continued demand for the expertise of our DCs, we envision IndiBrain as a model for future-oriented European doctoral training in computational neuroscience.

Keywords: human visual cortex,neuroplasticity,neuro imaging data analysis,functional magnetic resonance imaging,fmri,rehabilitation,ophthalmology,neurology
Social connections (SOCO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-03-01
End date: 2031-02-28
Duration (months): 60.0
Total project cost (EUR): 1499047.0
EU funding (EUR): 1499047.0
Participants: 1
Project status: SIGNED

Our brain both shapes and is shaped by social interactions, creating a dynamic link between neural processes and our social environment. Although previous research has identified brain regions involved in social functional processes such as perspective-taking and empathy, and has shown environmentally guided brain plasticity, we still lack a full understanding of the neurobiological basis of social thinking that combines internal brain processes and external social factors. Specifically, we do not fully understand how brain structure and function enable our social abilities while also being influenced by our social surroundings. This knowledge gap limits our understanding of human social behavior and how the brain adapts to changing social demands. This ERC Starting Grant ‘Social Connections’ (SOCO) aims to fill this gap by investigating the connection between social cognition and the social environment. My project uniquely combines precision neuroimaging, describing the microarchitectural basis of social cognition at the highest resolution, with population neuroimaging, tracking lifespan brain trajectories linked to social processes. First, I will map key social functional processes, perspective-taking and empathy, using a naturalistic social task. For this, I will use in vivo ultra-high resolution structural and functional brain scans (7 Tesla MRI) and independent post-mortem histological data to understand how the brain enables social cognition. Second, using publicly available large-scale datasets, I will investigate how genes, based on genome-wide association studies, and social environment, such as caregiving, socioeconomic status, and loneliness, interact to form the structure and function of brain areas involved in social behavior throughout life. By illuminating how internal functional processes and external social factors come together, I will advance our understanding of the neurobiological basis of social cognition with a novel and integrative approach.

Keywords: social neuroscience neuroimaging genetics population neuroscience
Multimodal Access for Intelligent Airports (MAIA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (JU-JTI)
Countries involved: Spain,Belgium,France,Serbia
Call: Fundamental Science and Outreach for Multimodality and Passenger Experience (HORIZON-SESAR-2022-DES-ER-01, 2022)
Start date: 2023-06-01
End date: 2025-11-30
Duration (months): 30.0
Total project cost (EUR): 1000000.0
EU funding (EUR): 1000000.0
Participants: 6
Project status: SIGNED

MAIA’s vision is that, within 5-10 years, CCAM and UAM based services will be available in an integrated manner with the airport infrastructure and the remaining access modes. AI tools and digital twins will be used for anticipating the impacts of different service configurations on the performance of airports as multimodal hubs. Aviation stakeholders will be able to make evidence-based decisions on how to implement, operate and regulate novel services in a way they improve passenger experience, increase capacity and help reach sustainability goals. The goal of MAIA is to develop a set of data analytics and modelling tools to support the evidence-based design and implementation of multimodal airport access solutions based on two passenger mobility innovations: shared autonomous vehicle fleets and unmanned aerial vehicle fleets. MAIA tools will monitor and anticipate passenger behaviour changes due to these new options, optimise vehicle dispatching under multimodal disruptions and recommend appropriate locations for vertiports, with the aim of maximising the contribution of these mobility innovations to the competitiveness and sustainability of the European aviation sector. The specific objectives of MAIA are (i) identify the opportunities and risks associated with passenger mobility innovations in a multimodal airport access context; (ii) develop MAIA-Engine, a toolset for a passenger-centric design and implementation of innovative multimodal airport access services, which includes new methods and tools for predicting passenger behaviour; (iii) develop MAIA-CCAM, a vehicle dispatching tool to support the operation of Shared Autonomous Vehicle (SAV) fleets in the airport access, able to mitigate multimodal disruption impacts; (iv) develop MAIA-UAM, a vertiport site selection framework to support the implementation of Unmanned Aerial Vehicles (UAV) services in the airport access, able to balance passenger experience, capacity and environmental sustainability.

Keywords: mobility innovations,ccam,uam,shared mobility,airport accessibility,data analytics,demand modelling,vehicle dispatching,vertiport location