Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Atomically Dispersed Heterobimetallic Catalysts for Cooperative C-H Bonds Activation (DUO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-11-01
End date: 2027-10-31
Duration (months): 60.0
Total project cost (EUR): 1499826.0
EU funding (EUR): 1499826.0
Participants: 1
Project status: SIGNED

The central objective of the DUO project is the development of original, well-defined and highly dispersed heterobimetallic supported catalysts using a molecular approach. Its chemical foundation is to take advantage of both (1) metal-metal cooperative effects and (2) site-isolation benefits, in combination, to achieve unprecedented and highly reactive active sites. This will ultimately lead to new bond activation pathways to tackle challenging catalytic transformations. Specifically, I target supported early/late pair-site catalysts, which are ideally suited to promote the heterolytic cleavage of strong C-H bonds. I will take advantage of this unusual reactivity in two classes of catalytic applications: (i) the late-stage isotopic labelling of organic substrates, such as active pharmaceutical ingredients, and (ii) CH4 and light alkanes valorization into higher hydrocarbons under non-oxidative conditions. These catalytic targets are not only scientifically demanding from a fundamental perspective but also possess high potential industrial outcomes. A leap forward with respect to today’s state of the art is required to achieve these goals. I propose to use an interdisciplinary approach at the forefront of current knowledge, combining the benefits of innovative and tailored molecular chemistry with those of surface science and heterogeneous catalysis. I have recently pioneered breakthrough concepts in this hot emerging research area which are a strong guarantee for the success of the DUO project.

Keywords: heterobimetallic complexes,surface organometallic chemistry,catalysis,methane valorization
Simulation-enhanced High-density Magnetomyographic Quantum Sensor Systems for Decoding Neuromuscular Control During Motion (qMOTION)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 3499763.0
EU funding (EUR): 3499763.0
Participants: 1
Project status: SIGNED

Being able to decode neural signals that control skeletal muscles with high accuracy will enable scientific breakthroughs in diagnostics and treatment, including early detection of neurodegenerative diseases, optimising personalised treatment or gene therapy, and assistive technologies like neuroprostheses. This breakthrough will require technology that is able to record signals from skeletal muscles in sufficient detail to allow the morpho-functional state of the neuromuscular system to be extracted. No existing technology can do this. Measuring the magnetic field induced by the flow of electrical charges in skeletal muscles, known as Magnetomyography (MMG), is expected to be the game-changing technology because magnetic fields are not attenuated by biological tissue. However, the extremely small magnetic fields involved require extremely sensitive magnetometers. The only promising option is novel quantum sensors, such as optically pumped magnetometers (OPMs), because they are small, modular, and can operate outside of specialised rooms. Our vision is to use this technology and our expertise in computational neuromechanics to decode, for the first time, neuromuscular control of skeletal muscles based on in vivo, high-density MMG data. For this purpose, we will design the first high-density MMG prototypes with up to 96 OPMs and develop custom calibration techniques. We will record magnetic fields induced by contracting skeletal muscles at the highest resolution ever measured. Such data, combined with the advanced computational musculoskeletal system models, will allow us to derive robust and reliable source localisation and separation algorithms. This will provide us with unique input for subject-specific neuromuscular models. We will demonstrate the superiority of the data over existing techniques with two applications; signs of ageing and neuromuscular disorders and show that it is possible to transfer these methodologies to clinical applications.

Keywords: biomechanics,quantum sensors,magnetic field recordings,skeletal muscle mechanics,continuum mechanics,in silico modelling,neuromuscular system
Optical sorting of cholesteric liquid crystal droplets (OPS-CLC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 209400.88
EU funding (EUR): 209400.88
Participants: 2
Project status: SIGNED

Interaction between light waves and chiral matter is a fundamental topic in optics and material sciences. When the matter is chiral, light can exert linear and angular momentum, optical torque, which has a differentiated sense depending on the handedness of the material and the helicity of the light. In this project, we propose to exploit the intrinsic chirality of cholesteric liquid crystals droplets on a microfluidic chamber to generate a differentiated rotation on different enantiomers of cholesteric liquid crystal. It has been shown numerically that rotating disks on a fluid produce a sorting effect, isolating the disks with different rotation senses. In this project, we propose to exploit the chirality in cholesteric liquid crystals to generate contactless enantioseparation of droplets with plane wavefront linearly polarised light, ensuring a robust and scalable enantioseparation technique. The project contemplates producing optical enantioseparation of polydisperse cholesteric liquid crystal droplets immersed in a microfluidic chamber. The project focuses on developing multidisciplinary aspects of light and matter interaction, specifically when there is a handedness, both in light and matter and is expected to generate impact and enhance new concepts in multiple fields ranging from applied mathematics to chemistry. The Researcher of the proposed project is Gregorio González, PhD candidate of the University of Chile, Chile, with experience in nonlinear dynamics induced by light interaction on liquid crystal layers. The Supervisor will be Professor Etienne Brasselet in the Singular Optics group, at the Host Institution, the University of Bordeaux, France.

Keywords: chirality,cholesteric liquid crystal,optical sorting,enantiomer
Renos: A Framework for a Performant and Sustainable Ultra-Reconfigurable Computing Continuum (RENOS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-04
End date: 2027-06-03
Duration (months): 24.0
Total project cost (EUR): 214344.72
EU funding (EUR): 214344.72
Participants: 1
Project status: SIGNED

The current increase in popularity of smartphones, Internet of Things devices, as well as wearable devices, has brought with it an increasing interest in ubiquitous services based on cloud computing. These devices connect to the Internet to reach the cloud data centres, which host services that these devices could not execute by themselves. Furthermore, research is currently focused on complimenting cloud computing with the "Computing Continuum" paradigm, where computations are distributed, not only through cloud data centres, but also through other devices increasingly closer to users. The Computing Continuum offers promising improvements in terms of performance compared to traditional cloud computing, enabling new paradigms such as Industry 4.0 or eHealth. However, traditional cloud data centres, as well as the ubiquitous access to them through the Internet, consume up to 460 TWh of energy per year, and are responsible for 0.9% of the total energy-related greenhouse gas emissions. Hence, an approach to the Computing Continuum based on simply placing more servers closer to users, continuously powered on, can further increase the already large carbon footprint of the cloud paradigm. Therefore, to enable for a sustainable and performant future for computing, the management of the Computing Continuum is key. To provide a key enabler for this situation, we propose Renos, a system able to continuously adapt, optimize and orchestrate both the Computing Continuum's devices and the applications that run on them, aimed at achieving more sustainable and performant computing services and infrastructures. Renos is envisioned as an artificial intelligence-based system to be used by Computing Continuum providers, and integrated into industry-ready orchestrators. The Renos project is not only an innovative and ambitious project that can make the European Computing Continuum more competitive, it is also in line with the MSCA Green Charter, the European Green Deal, and the EU SDGs.

Keywords: sustainability,computing continuum,orchestration,adaptation,performance,artificial intelligence,software engineering
Back in the matter. New and 'Old' Materialist Feminisms: Contributions to Contemporary Debates (FEMAT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-03-02
End date: 2028-03-01
Duration (months): 24.0
Total project cost (EUR): 242260.56
EU funding (EUR): 242260.56
Participants: 1
Project status: SIGNED

The purpose of FEMAT is to conduct a philosophical study of both new and ‘old’ materialist feminisms, examining their contributions to contemporary debates. Despite the convergences between these currents, the dialogue between Materialist Feminism (MF) and New Materialist Feminism (NFM) has not yet been fully explored. FEMAT argues that a comparative analysis of MF and NMF can chart new paths for feminist theory. One of FEMAT's main insights is to illuminate the role and significance of a highly controversial form of materiality: biological materiality, which has become a watershed in contemporary feminist debates. This project aims to develop a critical materialist feminist approach to the category of 'sex,' treating biological materiality as one form among many, rather than as the sole determinant. In doing so, FEMAT seeks to address two significant challenges in feminist theories: linguistic or discursive reductionism, which impedes the analysis of the economic and material dimensions of sexist violence, and the essentialism or ontologization of sexual difference, which tends to re-naturalize the category of sex. The implications of these debates extend beyond philosophy and directly impact pressing social issues. The re-naturalization of sex has had a regressive effect on various human rights issues, notably including the increasing refusal to recognize trans identities, not only among conservative sectors but also within feminist circles. By developing a materialist epistemological framework, FEMAT aims to create critical categories and arguments that can enhance public policies from a more inclusive and democratic human rights perspective, emphasizing the interrelation between theory and practice.

Keywords: materialist feminism new materialist feminism materialism neomaterialism trans materialism postconstructivism feminist philosophy feminist theory
SESAM2030 - science, citizens, schools and a hungry planet (SESAM2030)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Denmark
Call: European Researchers' Night 2022-2023 (HORIZON-MSCA-2022-CITIZENS-01, 2022)
Start date: 2022-07-01
End date: 2024-06-30
Duration (months): 24.0
Total project cost (EUR): 299722.0
EU funding (EUR): 299722.0
Participants: 1
Project status: CLOSED

The climate crisis is obvious, the nature needs protection, biodiversity is under threat and the environment needs to be taken care of. But at the same the growing planetary population needs to be fed. These are the major challenges that SESAM2030 addresses and research is a key element. Understanding & participation from citizens & youth are central elements if research are to thrive. They have not only their democratic rights to decide about research, they are also potential suppliers of data, beneficiaries in the exploitation of research results and they indispensable when it come to the behavioral change that often follows from new research. Without insight into the idea and nature of research societies will not prosper. We use the idea of ecosystems services to apply a model of nature where nature provides and can be enjoyed. Obviously these needs be balanced within planetary boundaries. We pick science cases in the domain of the bioeconomy to increase the understanding of role of research in society, young peoples interest in research careers and to counteract stereotypes of researchers. Our program unfolds in 2 editions for 22 & 23 in DK but with reach out to SE & DE. In the Edition EAST we work with 2 schools in Copenhagen (DK) & 1 in Malmoe (SE). In Edition WEST we work with 2 South Jutland (DK) & 1 in Flensburg (DE). We will be international, regional and take advantage of proximity. Schools will present the outcomes on Saturday 24 September 2022, Thursday 29 September 2022, and Saturday 12 November 2022 and on Friday 29 September in 2023. SESAM2030 develops in a pupil driven way each year over 6 weeks in parallel with the awareness raising campaign and executes on 2 occasions in Sept.: on School on Fridays & as a NIGHT-on-the-town on Saturdays. The final Saturday event (E/W) uses 5 instruments to achieve objectives: Science Shows (on stage), Sofa Talks (on Stage), Science Stations, EU corner with Young MSCA Researchers Pitches and Live Citizen Science (a Mass Experiment).

Keywords: climate,nature,biodiversity,soil health,sdg s,agriculture,food,science,research,citizens,youth,schools,bottom up,participation,early career resarchers
Bound to accelerate the roll-out and expansion of Energy Communities and empower consumers as fully-fledged energy market players (COMMUNITAS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Portugal,Greece,Denmark,Poland,Croatia,Netherlands,Spain,Italy
Call: Supporting the action of consumers in the energy market and guide them to act as prosumers, communities and other active forms of active participation in the energy activities (HORIZON-CL5-2022-D3-01, 2022)
Start date: 2023-01-01
End date: 2026-06-30
Duration (months): 42.0
Total project cost (EUR): 7000664.99
EU funding (EUR): 5999602.5
Participants: 21
Project status: SIGNED

With its “Clean Energy for all Europeans” package (CEP), the European Commission formally recognised and instrumentally brought forward community energy projects, including definitions for “Renewable Energy Communities” (RECs) and for “Citizen Energy Communities” (CECs). The new concepts introduced in the CEP set the course for a more active role of EU citizens in the energy markets. To fully concretize the benefits envisioned by the CEP, a myriad of barriers needs to be overcome and progress needs to be done to clarify and streamline the concepts of REC and CEC, enabling its uptake by all interested citizens. Motivated by that challenge, COMMUNITAS will promote energy citizenship, enabling citizens to take control of their own path towards sustainability by becoming an active element of the energy markets. The project will deliver a Knowledge Base that will provide users with technical, administrative, and legal information on ECs, streamlining the creation and expansion of this concept. COMMUNITAS will also deliver an innovative set of tools - capitalizing on technologies such as IoT, Blockchain and Cloud Computing - to unlock citizens’ active participation in energy markets and communities (all integrated into an open, digital “one-stop-shop” COMMUNITAS Core Platform (CCP)), allowing EC members to have an aggregated position in the energy markets or explore ancillary services using different energy assets or load profiles of the community. As a project that aims to position citizens in the centre of energy markets, COMMUNITAS has citizens at the centre of its own approach: citizens will be involved in Social and Policy Labs throughout the whole project, in order to frequently factor in their feedback, wishes, needs into the core developments of the project.

Keywords: energy communities demand response energy markets social and citizen engagement flexibility distributed energy resources participatory laboratory p2p energy markets
Unravelling the history of underSEA oceanic plateau VOLCanism and its environmental impact in Earth’s past (SEA-VOLC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1499670.0
EU funding (EUR): 1499670.0
Participants: 1
Project status: SIGNED

Oceanic plateaus are amongst the largest geological phenomena on Earth, and their undersea volcanic formation had profound environmental effects, such as climate warming and ocean anoxia. Whilst huge progress has been made to link their land-based counterparts, continental flood basalt provinces, with climate change and mass extinctions, oceanic plateaus have been comparatively understudied due to their limited accessibility and relatively benign ecological impact. Yet, plateau volcanism triggered severe climatic and environmental disruption, but the precise mechanism(s) by which they influenced the Earth’s surface are unclear. Further, most known oceanic plateaus formed in the Cretaceous, with their likely existence and environmental impact earlier in Earth’s history seldom considered. The SEA-VOLC Project utilizes my expertise in studying past environmental crises and geochemically fingerprinting large-scale volcanism to reconstruct the mechanism(s) by which oceanic plateaus triggered global change, and for the first time, investigate the history and impact of older plateaus that no longer exist. Combining inorganic and organic geochemistry, I will create global maps of trace-metal nutrient disruption and biological productivity during times of Cretaceous and Triassic plateau activity. Resolving the relative environmental impact of this process vs CO2 output and warming is critical to understand whether continental and oceanic volcanism influenced the Earth system differently, and why the former was often more lethal. State-of-the-art geochemical proxies that have recorded Cretaceous episodes of undersea volcanism will be applied to Silurian–Devonian sedimentary archives of Cretaceous-like anoxic events, showing whether earlier environmental crises were also linked to plateau formation for the first time. Exploring this possibility provides a unique new perspective how the Earth’s interior and its interactions with surface environments have evolved over time.

Keywords: oceanic plateau volcanism,oceanic anoxic events,carbon cycle
Deciphering the interplay between mitophagy, epigenetic regulation, and neurodegeneration in ageing (MitoEpigeNeAge)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Greece
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-03-01
End date: 2028-02-29
Duration (months): 24.0
Total project cost (EUR): 181423.68
EU funding (EUR): 181423.68
Participants: 1
Project status: SIGNED

The "MitoEpigeNeAge" research proposal seeks to uncover the molecular mechanisms of age-related neurodegeneration by focusing on the interplay between mitophagy, redox-regulated histone methylation, and neuronal death. Brain ageing is characterized by the accumulation of damaged mitochondria and epigenetic changes, leading to neurodegeneration. Mitophagy, the process that clears damaged mitochondria, declines with age but extends lifespan and offers neuroprotection when activated. However, its impact on the epigenome remains unclear. The project will utilize Caenorhabditis elegans due to its well-defined nervous system and evolutionary conservation of neuronal ageing mechanisms. Advanced technologies will analyse chromatin accessibility and gene expression in redox-sensitive neurons. Super-resolution imaging and optogenetics will allow precise manipulation of mitochondrial damage and mitophagy in live animals. Key objectives include: 1) Monitoring chromatin accessibility, histone methylation, and gene expression in wild-type and mitophagy-deficient worms; 2) Developing in vivo reporters to track chromatin modifications during ageing and mitophagy induction; 3) Using optogenetics to assess the effects of mitochondrial damage on histone methylation in neurons; 4) Exploring if mitophagy-inducing interventions provide neuroprotection through changes in histone methylation linked to redox homeostasis; 5) Conducting a genetic screen to find mitophagy modulators that enhance mitochondrial quality control, histone methylation, and resistance to neurodegeneration. This project supports the researcher’s long-term goals and the MSCA's mission to promote innovative research. Its successful completion will greatly enhance understanding of age-related neuronal decline, with significant benefits for human health. The MSCA grant would be transformative, providing essential resources to advance the research and establish the researcher as a group leader in the ageing field.

Keywords: ageing,mitophagy,epigenetic modifications,neurodegenerative diseases,oxidative stress,c elegans,mitochondria dynamics,chromatin remodelling,neuronal apoptosis,ageing pathways,aggregation