Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Innovative Techniques and Models to Study Glia-Neuron Interactions (EDU-GLIA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,United Kingdom,Germany,Israel,Germany,France,Sweden,Czechia,United Kingdom,Germany,Slovenia,Germany
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-09-15
End date: 2013-09-14
Duration (months): 48.0
Total project cost (EUR): 3285553.81
EU funding (EUR): 3285553.81
Participants: 13
Project status: CLOSED

It became evident over the last 20 years that glial cells are involved in virtually every aspect of nervous system function. Neurons and glia exchange chemical signals that are essential for the normal function of the nervous system, and are crucial in disease. Recently it was discovered that glial cells also act as neural stem cells both in early development and adulthood, and in synapse formation. This rapid progress in glia research generated not only many new insights but also numerous new questions, and it became obvious that to deal with the complexity of glia-neuron interactions and to formulate new concepts in the field, we need novel experimental paradigms and methodologies. The EdU-GLIA network is aimed at equipping young researchers with the most advanced skills knowledge in glial cell research, in order to generate a new generation of scientists dedicated to resolving open questions of glia-neuron interactions. We will offer young investigators high quality interdisciplinary projects that will be individually tailored and each will be supervised by two mentors. Our team of supervisors consists of leading experts in the field, including an industrial partner. EdU-GLIA is based upon current original and promising research models ranging from basic science to clinical application, and on the most advanced and sophisticated research techniques. To complement the research projects, we will offer the young scientists a rich selection of courses, workshops, guest lectures, and symposia. This program will not only provide insights into research techniques and paradigms complementary to the individual projects, but will also strengthen professional skills such as writing papers, presenting data, and ethical conduct, enhancing the career prospects of the fellows. In summary, the main objective of EdU-GLIA is to train promising young researchers for careers in basic as well as in translational research, including clinical application and industry.

Keywords: neurosciences,neurophysiology,neurobiology,glia,glia-neuron interaction
Novel multifunctional cyclodextrin-based nanocarriers for drug encapsulation and delivery as a strategy to overcome current therapeutic drawbacks. (CYCLON)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Greece,Spain,France,Iceland,Italy,Italy,Sweden,Spain,Hungary
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-10-01
End date: 2013-09-30
Duration (months): 48.0
Total project cost (EUR): 2415547.0
EU funding (EUR): 2415547.0
Participants: 9
Project status: CLOSED

There is a high demand for the development of new drug delivery strategies to combat major diseases in our society, particularly cancer. Current treatments are based on high efficacy drugs, however their non-selective uptake by both normal and tumor cells as well as the development of multidrug resistance (MDR), constitute major hurdles. Resistance is also associated with the use of nucleoside analogues as anticancer drugs in vivo. Photodynamic therapy (PDT), aims at selectively killing neoplastic lesions by the combined action of a photosensitizer and visible light. Passive targeting, involving enhanced permeability and retention effect, allows the accumulation of drugs on tumor sites, and concomitant active targeting with suitable functionalities, constitute properties currently associated with polymeric delivery systems. Cyclodextrins (CDs) are biocompatible and biodegradable oligosaccharide nanocages, known to improve the solubility, stability and bioavailability of drugs. Scattered literature reports incidents that CDs may constitute potential means to overcome certain forms of MDR, or to effectively deliver photosensitizing anticancer drugs preserving their photodynamic properties. This network, highly specialized in CD chemistry, photochemistry, in vitro drug evaluation and in vivo applications, proposes to synthesize diverse families of new CD derivatives to build a platform of CD-based drug delivery nanosystems with a variety of architectures. These new generation nanocarriers, encompassing many cavities in a nm-sized vehicle, will possess high drug loading capacity, improved permeability and retention effect, enhanced targeting and complete biocompatibility. Their mode of action will be assessed in vitro and in vivo. These goals will be achieved via a strong training program of ESRs and ERs in a highly collaborating, multidisciplinary and application oriented program, with full participation of an SME partner, a leader in CD applications.

Keywords: health sciences,natural sciences,nanomedicine,cyclodextrins,drug delivery,nanocarriers,anticancer drugs,photosensitizing drugs
Risk Management and Risk Reporting (RISK)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany,Netherlands,Spain,Italy,Germany,Switzerland
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-09-15
End date: 2013-09-14
Duration (months): 48.0
Total project cost (EUR): 3726930.86
EU funding (EUR): 3726930.86
Participants: 8
Project status: CLOSED

The financial markets turbulence in recent months serves to highlight the key roles of risk management and risk reporting in both private and public sectors. The rapid innovations of financial structured products and the difficulty in valuing and reporting them present a huge challenge to both investors and risk regulators. The developments of Basel II and Insolvency II regulatory frameworks have been seen as less than effective response to this increasing complex financial problem. The proposed ITN brings together the research excellence in financial reporting and governance, quantitative finance, finance and banking theory, systemic risk, and market microstructure from five universities, a central bank and two risk management industry experts from across Europe with the common goal of training young researchers in this field. They are supported by three other academic institutions and eight industry partners ranging from investment bank, insurance company, software and data service providers, and professional organisations all committed to help train the young researchers and some with the provision of internship experience. In a complex system, it is important that young researchers understand financial risks from many different perspectives, have the specialist expertise to deal with it and some practical firsthand experience with the industry. Researchers trained in such an integrated scheme will be better equipped in dealing with financial risk in their future careers in both public and private sectors.

Keywords: risk regulation,risk disclosure,governance,sustainability,basel ii,solvency ii,risk concepts,macro finance,systemic risk,market microstructure and liquidity risk,quantitative techniques
Surface Engineering for Antifouling - Coordinated Advanced Training (SEACOAT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,Sweden,Germany,Switzerland,Italy,United Kingdom
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2010-01-01
End date: 2013-12-31
Duration (months): 48.0
Total project cost (EUR): 3281108.21
EU funding (EUR): 3281108.21
Participants: 8
Project status: CLOSED

The main research goal of SEACOAT is to improve understanding of biointerfacial processes involved in the colonisation of surfaces by marine fouling organisms. Our vision is that this enhanced understanding will inform the future development of new, environmentally-benign materials and coatings for the practical control of marine biofouling. Our principal objective is to discover which nano- and micro-scale physico-chemical properties of surfaces influence the adhesion of fouling organisms, through the use of surface engineering technologies to fabricate coatings that vary systematically in relevant surface properties, and length scales. We will use advanced surface analytical methods to characterise test surfaces for relevant physico-chemical surface properties and how these change after immersion. Parallel adhesion bioassays using a range of representative marine organisms will test intrinsic antifouling properties of surfaces. The network is an interdisciplinary cooperative of chemists, physicists and marine biologists. Intersectoral aspects unite basic and applied scientists working in universities, a large company and an SME. The project’s S&T objectives will be delivered through research in 4 main Work Packages: viz. WP1-Surface Engineering, WP2-Surface Analytics, WP3-Bioadhesion, WP4- Integration. Two additional Work Packages (WP5, WP6) will be concerned with the Dissemination of project results and the Management of the Network respectively. The aim of the Training Programme is to increase the knowledge base and experience of trainees in each of the Thematic Areas and to develop their transferable skills for future careers in industry or academia. Six training objectives will be delivered through a suite of 7 Core Skills Areas (Research Project, Advanced Training Courses, Project Conferences, International Winter Workshop, Career Development Plan, Generic Research Skills, Transferable Research Skills).

Keywords: nanotechnology,nanobiology,interfacial science,surface science,materials science,polymers,biofouling,bioadhesion,marine science
Enzyme technology for Lean and Green food processing (LEANGREENFOOD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark,Netherlands,Greece,France,Netherlands,Denmark,Denmark,Denmark,Spain,Spain,Germany,Denmark
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-10-01
End date: 2013-11-30
Duration (months): 50.0
Total project cost (EUR): 3427528.0
EU funding (EUR): 3427528.0
Participants: 12
Project status: CLOSED

Plant material, including industrial vastes from grain production and the juice and vegetable oil industry, is a rich source for valuable functional ingredients for processed foods. Processing of relevant agricultural vaste and product refinery needs, however, rethinking, as it often depends on use of chemical reagents of environmental concern and of harsh reaction conditions with high energy demands. Large requirement of process water adds further to the environmental load. The LeanGreenFood Initial Training Network will focus on solutions to reduce consumption of water and energy, both scarce resources in the future. Carbohydrate and peptide processing to yield value-added food ingredients will be based on the use of mono-component enzymes and on technology developed for highly concentrated solution systems. The LeanGreenFood.network will train 13 ESR’s and 4 ER’s to develop and implement new enzyme-based technology for future development of a more sustainable production. The training will include development and use of specific on-line analytical methods for process monitoring. The use of mechanical treatment and high-pressure tuning of enzymes for process optimization will open up for further process control. The training programme and conferences will be open for participants from outside the Network with the perspective of training a new generation of food scientists.

Keywords: high level training programme,sustainable food production,re-thinking of food production systems,enzyme technology,lean and green concept,improve career prospects
Europe, Brain and Music: New perspectives for stimulating cognitive and sensory processes (EBRAMUS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,France,Germany,Germany,United Kingdom,Belgium,France,Poland
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-12-01
End date: 2013-11-30
Duration (months): 48.0
Total project cost (EUR): 2341796.0
EU funding (EUR): 2341796.0
Participants: 8
Project status: CLOSED

EBRAMUS investigates an attractive, promising new research avenue at the intersection of neuroscience, the human sciences and new technologies: can music boost sensory, cognitive and motor development in normal and impaired children and adults? The project will assess this issue in an integrative way by combining behavioural, neurophysiological, neuropsychological and computational methods. Three research topics will cover both basic and clinical research using music in the rehabilitation of various patient populations and the elderly. The 1st topic focuses on the rehabilitation of auditory functions and language deficits, the 2nd focuses on the benefits of music for more general cognitive functions (learning, memory) and the 3d on timing behaviour and the use of music in motor rehabilitation. The overall project will increase our understanding of brain functioning and will have a tremendous impact on clinical and educational applications (developing new diagnostic tools, training and rehabilitation techniques, also leading to industrial developments) and for new music technology for the general public. EBRAMUS will foster strong links among partners at the forefront of this interdisciplinary research area. It provides an invaluable opportunity for young researches to gain state-of-the art knowledge in the field of cognitive neurosciences and interdisciplinary research by benefiting from exchanges within the network, from the offered training program (e.g., topical summer schools/workshops) and the project’s good balance between basic research and clinical approaches. The training will ultimately increase students’ career opportunities, thanks to the network’s academic and industrial partners. EBRAMUS partners present a strong network with common and complementary expertise, thus providing ideal multi-site and multidisciplinary training for young researchers and, more generally, providing the opportunity to considerably strengthen Europe’s position in the field.

Keywords: health sciences,neurosciences,neurophysiology,neuropsychology,rehabilitation,social sciences,experimental,development,clinical psychology,humanities,music,computer science,systems design
SUPramolEculaR functional nanoscale archItectures for Organic electronics: a host-driven network (SUPERIOR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,Germany,United Kingdom,Belgium,Germany,Italy,United Kingdom,Belgium,Netherlands
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2009-10-01
End date: 2013-09-30
Duration (months): 48.0
Total project cost (EUR): 3793675.59
EU funding (EUR): 3793675.59
Participants: 9
Project status: CLOSED

SUPERIOR aims at providing top-quality cross-disciplinary and supra-sectoral training to a pool of promising young researchers, in an area at the interface between Supramolecular Chemistry, Materials- and Nano-Science, Physics and Electrical Engineering. SUPERIOR appointees will be formally trained in lecture courses, dedicated schools and workshops, and through an ambitious and carefully planned research activity that benefits both from the expertise of world-leading senior investigators and of younger and energetic PIs with remarkable track records in both training and research. SUPERIOR is designed to generate new scientific and technological knowledge by combining supramolecularly-engineered nanostructured materials (SENMs), mostly based on organic semiconductors, with tailor-made interfaces to solid substrates and electrodes, for fabricating prototypes of optoelectronic devices. We are particularly interested in developing multiscale SENMs for transistors (FETs), in-plane diodes single-photon emitters, and especially solar cells (PVDs) and organic light-emitting diodes, OLEDs. The specific training and research objectives are: 1. Supramolecular synthetic chemistry of electrically/optically 1D and 2D (macro)molecules 2. Hierarchical self-organisation of multifunctional SENMs at surfaces. Multiscale SPMs studies of physico-chemical properties 3. Time-resolved photophysical studies of single-molecules and SENMs 4. Time-resolved spectroscopy of materials and devices 5. Modelling the geometric and electronic structures and the optical properties of SENMs 6. Advanced devices processing/(nano)fabrication 7. Formation of controlled interfaces of SENMs with substrate and electrodes 8. Devices I: FETs: Measurement of charge mobility in stacks, also upon photodoping. 9. Devices II: PVDs – addressing the charge collection problem. 10. Devices III: Emissive devices - Single photon emitters and OLEDs 11. Dissemination and strategic development 12. Management

Keywords: macromolecular chemistry,optoelectronics,molecular electronics,molecular chemistry,carbon chemistry,photochemistry,surface chemistry
Management of Emergent Technologies for Economic Impact (MANETEI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Netherlands,Finland,Slovenia,France,Ireland,Germany,Spain,Germany
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2010-02-01
End date: 2014-01-31
Duration (months): 48.0
Total project cost (EUR): 3832975.92
EU funding (EUR): 3832975.92
Participants: 10
Project status: CLOSED

The ManETEi network offers a research-led training programme to create a rigorous collaborative research agenda centred on the multifaceted phenomenon of managing emergent technologies for maximum economic and societal impact. It will have advanced capacity-building and career development that will benefit the early-career and experienced researchers needed to ensure Europe becomes a leading knowledge economy driven by its unique ERA. The network has identified arguably Europe’s most important opportunity for its future management researchers, managers and policy makers. The investment by Member states, EU and industry in Bio-, Nano-, Info- and cognitive (NBIC) emerging science and technology are making jointly is the largest ever seen. This creates a need for both increased capacity and new competencies in business and management for linking advances in emerging technology with business and economic exploitation. Yet demographic studies indicate Europe’s management training and research capacity is set to decline. ManETEI brings together 7 of Europe’s leading Business Schools, the Fraunhofer ISI, an European global high technology manufacturer (Bayer GmbH) supported by a diverse group of associate partners from different industries, sectors, technologies and countries. They will provide a stimulating and active learning environment to enhance trans-national mobility, inter-institutional experience and exposure to a range of scholarly perspectives from the disciplines of management, economics and technology. It will create a platform for researchers to investigate the multifaceted phenomenon of managing the emergent technologies that promise the greatest competitiveness and growth of the European economies. The network members are highly experienced in participating in EU funded research and its implementation at all levels. They all share commitment for future research and training collaboration based on the principles created by this network.

Keywords: innovation management,technology management,business economics,innovation strategies,new technology based firms,nanotechnology,biotechnology,computer technology
Training Urology Scientists to develop Treatments (TRUST)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,Belgium,Belgium,Netherlands,Poland,Netherlands,United Kingdom
Call:  (FP7-PEOPLE-ITN-2008, 2008)
Start date: 2010-01-01
End date: 2014-12-31
Duration (months): 60.0
Total project cost (EUR): 3235968.0
EU funding (EUR): 3235968.0
Participants: 11
Project status: CLOSED

Urinary Incontinence (UI) affects around 10% of the population (more than 70 Million people in the EU) and unfortunately - due to the aging population - is an increasing cause of impaired quality of life. The most common cause of UI is called the Overactive bladder syndrome (OABS) of which the underlying complex bio-molecular mechanisms are poorly understood. Many distinct tissues (nervous system, urothelium, interstitial cells, smooth muscle cells) contribute to OABS but their specific roles remain unknown. As a result, no effective non-invasive therapy without side effects is available or can be developed without a profound integration of multiple scientific disciplines. The TRUST ITN proposes an interdisciplinary research training network of 8 European university institutes and 3 enterprises, with a wide variety of complementary expertise in UI and OABS. The network covers all required disciplines from anatomy, urology, neuroscience, pathology, pharmacology, biomedical engineering, clinical science, bioinformatics to diagnostic- and drug development, that must be applied on cellular-, organ- and whole body levels. Currently most researchers are not trained to deal with such a great variety of disciplines, and are thus insufficiently prepared to cope with the modern and increasingly urgent challenges of urology research. In the TRUST project 10 early stage researchers and 5 experienced researchers will receive training from different leading European research institutes on multiple complementary disciplines that will empower them to explore the and unravel the mechanisms underlying OABS and to develop novel diagnostic, prevention and treatment strategies. Moreover, the integrated research training programme will transfer practical skills, knowledge and experiences to stimulate successful medical (commercial) exploitation of these results. Finally, the unique multidisciplinary scientific profiles of the researchers will open-up promising career perspectives.

Keywords: urinary incontinence (ui),therapy,diagnosis,sensory,overactive bladder syndrome (oabs)