Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
EXPLORING NOVEL HALO-PHOTOAUTOTROPHS FOR A CIRCULAR BIOECONOMY VIA TRANSFORMATION OF SYNGAS INTO MEDICAL AND PHARMACEUTICAL COMPOUNDS (HALO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-02
End date: 2026-09-01
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 3
Project status: SIGNED

The European Union has clear targets in place to maintain an average global temperature 2˚ below pre-industrial levels, as shown by the Green Deal, Circular economy action plan, and Bioeconomy strategy; reducing emissions levels, incentivising a green, circular economy, and consolidating Europe's resources and environments. Gasification can convert organic waste into a potential feedstock (syngas), while reducing landfill volume, and emissions. Furthermore, microbial processes are seen as a potential next step to de-fossilise the industrial chemical industry. Purple phototrophic bacteria (PPB) can produce a host of value-add compounds while fixing inorganic wastes (e.g., CO2), gaining interest as a microbial tool for next-generation biorefineries. As such, the HALO project seeks to use halophilic PPB to convert syngas, CO2/CO/H2, into a host of valuable chemicals (medical, pharmaceutical products). The host of target compounds, the osmolytes ectoine and hydroxyectoine, the amino acid proline, the enzyme ubiquinone, and carotenoids (β-carotene, lycopene, spheroidene, spirilloxanthin) have high market value, with lycopene reported at 5500€/kg. In order to develop PPB syngas valorisation technology, specific PPB's ability to fix CO2 and CO must be determined and new high mass transfer bioreactors designed. HALO is a multi- and inter-disciplinary research project which aims to help achieve the EU's Green Deal goal of continental carbon net-zero by 2050 while creating green, competitive, and sustainable bioindustries and economies. On a global scale, HALO will help fulfil the United Nations' Sustainable Development Goals 13, 11, and 12 (Climate Action, Sustainable Cities and Communities, Responsible Consumption and Production, respectively). Additionally, this project will allow the researcher's current abilities to flourish, while learning new techniques and methods from pioneering researchers outside of his immediate field of expertise.

Keywords: purple phototrophic bacteria ppb climate change mitigation dual co2 and co treatment ghg bioconversion extremophile halophile carotenoids pigments ectoines production pharmaceuticals
Cuban Higher Education Reform: a Policy Ethnography (CHERPE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-07-01
End date: 2025-06-30
Duration (months): 24.0
Total project cost (EUR): 230774.4
EU funding (EUR): 230774.4
Participants: 1
Project status: CLOSED

Higher education (HE) is one of the flagships of the Cuban Revolution. Research on Cuban HE policies focuses on the desired outcomes within policy documents. Nevertheless, there is a lack of studies analysing how stakeholders implement those policies on the ground by translating policy documents into practices and relationships; or how policy documents shape universities, organisational cultures, people's identities and power relationships. Therefore, it is timely to describe how Cuba’s centralised HE policy documents are translated on the ground at the University of Holguin from 2000 onwards. Just in 2000, the so-called Third Educational Revolution began in Cuba, bringing far-reaching transformations within higher education to date. It is a large-scale process of changes ethnographically unexplored. By undertaking both the anthropology of policy and anthropology of education approaches, CHERPE draws the following objective: to describe how university actors translate the Cuban HE policy documents on the ground into relationships, powers, actions, new organisational structures, individual or collective strategies and new identities. The University of Holguin in Cuba will be a case study. Coming from the anthropology of policy approach, ‘studying through’ is a sound strategy to study processes of political transformations through space and time in which I will combine documentary analysis, interview, focus group and participant observation. By using these interdisciplinary methods, I will bring a pioneering ethnographic methodology to the Cuban context that will advance both the fields of policy studies and anthropology. The fellowship will furnish me with expertise in policy and HE studies and will drive my publication record, allowing me to apply for a better academic position. I will further the Cuban HE policy field and the anthropological approaches that CHERPE addressed.

Keywords: anthropology of policy higher education policies anthropology of education cuban studies
Rethinking Peace and Policing in the Favelas in Rio de Janeiro (RECONSIDER)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway,Brazil
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2028-08-31
Duration (months): 36.0
Total project cost (EUR): 311957.04
EU funding (EUR): 311957.04
Participants: 2
Project status: SIGNED

This project will explore bottom-up, civil-society-driven security alternatives in the favelas in Rio de Janeiro as marginalised, racialised and criminalised neighbourhoods, their transformative potential and their comparison to post-conflict community policing and security reform. The project is a global collaboration between NMBU, Norway and PUC-Rio, Brazil. It contains the following three research objectives: 1. To explore bottom-up, civil-society-driven security alternatives in the favelas in Rio de Janeiro. Data will be gathered through a participatory project with the favela organisations Coletivo Papo Reto, Observatório de Favelas and Redes da Maré, and will include 20 semi-structured interviews, discussion groups, participant observation and open forums for discussions on non-violent alternatives to policing and the potentials (or lack thereof) for community policing projects in the favelas. 2. Study where and how these efforts to ensure human security meet the state and its public security apparatus. Here, data will be gathered through participant observation with Coletivo Papo Reto, Observatório de Favelas and Redes da Maré, and include 20 semi-structured interviews with politicians, members of the judiciary and public security officials. 3. Bring lessons on community policing alternatives and interactions with the state from the favelas and see how they are translatable to other cases of civil-society led/engaged community policing projects. Data will be gathered from secondary sources case studies on post-conflict community policing at the ICT4COP Center at NMBU. The project contributes knowledge on civil society-led community policing in racialised, criminalised neighbourhoods, community alternatives from an intersectional, decolonial community perspective from the global south, and to the study of peace formation and hybridity in violent non-conflict contexts. It also explores innovative co-production through participatory research in the favelas.

Keywords: favela,community policing,peace,peace formation,local agency,public security reform,human security,rio de janeiro,decolonial,demilitarisation,urban margins,state violence
Prokaryote proteomics at high temperature for single cells (PROHITS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Belgium,Norway,Austria,France,Hungary,Germany
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 2711362.63
EU funding (EUR): 2474352.0
Participants: 11
Project status: SIGNED

A sustainable climate and an ecosystem-friendly economy demands novel ‘cell factories’, in which organisms convert renewable biomass into various biomaterials that would otherwise be derived from fossil fuels or (harsh) chemistry. Especially promising is the use of thermophilic bacteria and archaea that operate at high temperatures, as this can enable more efficient production processes. However, we currently know very little about the cellular protein machinery (or proteome) of thermophiles, which limits our ability to efficiently use them in cell factories. The PROHITS project therefore creates a network for nine doctoral candidates to develop mass spectrometry (MS) driven proteomics approaches to study the in vivo proteome of thermophiles, and to apply the obtained insights to cell factory development. The first aim is to perform proteomics on single prokaryotic cells using advanced microfluidics, MS instrumentation and data analysis, to observe how proteomes vary in individual cells. The second aim is to enable thermal proteome profiling approaches for thermophiles, to observe how their proteomes respond to temperature changes. The third aim is to apply the proteomics insights for predicting how in vivo proteins respond to high temperatures, and to create more detailed genome-scale models of thermophiles. This information is used to improve an existing cell factory that produces lipids for medicine encapsulation, and to expand knowledge of thermophiles that can be used as cell factories. To achieve this, PROHITS creates an integrated pipeline of experimental and computational approaches, built within a collaborative network of academics and industry. The doctoral candidates will obtain comprehensive and highly complementary skills, ranging from cutting-edge proteomics analysis, over data analysis and prediction, to systems biology approaches to optimize cell factories, which will enable them as future leaders of a thriving and forward-looking European bioeconomy.

Keywords: single cell separation,thermal proteome profiling,cell factories,proteome dynamics,computational biology,machine learning,genome scale models,thermal response,thermophile
CLIMED-FRUIT : Adaptation to climate change and mitigation for perennial crops in Mediterranean Area (CLIMED-FRUIT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Coordination and support actions
Countries involved: France,Italy,Croatia,Serbia,Spain,Greece,Portugal
Call: Broaden EIP Operational Group outcomes across borders by means of thematic networks, compiling and sharing knowledge ready for practice (HORIZON-CL6-2021-GOVERNANCE-01, 2021)
Start date: 2022-10-01
End date: 2025-09-30
Duration (months): 36.0
Total project cost (EUR): 1996220.0
EU funding (EUR): 1995969.75
Participants: 9
Project status: SIGNED

CLIMED-FRUIT aims to broaden EIP Operational Group outcomes across borders, in the field of adaptation to climate change and mitigation for perennial crops in Mediterranean Area, by compiling and sharing knowledge ready for practice.

Keywords: climate,mediterranean,adaptation,mitigation,perennial plants,operational groups,network,eip agri
iSMILE - integrated scalable microLED engines (iSMILE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 2390375.0
EU funding (EUR): 1673262.5
Participants: 1
Project status: SIGNED

Today´s microelectronics is suffering from the fact that silicon cannot emit light. Otherwise, technological road blockers like the communication bottleneck of microprocessors or like bulky displays hindering the rocket start of augmented reality could easily be overcome. The EIC accelerator project i`SMILE will bring light to microelectronics. Our goal is to be an enabler for a natural integration of microelectronics with microphotonics. I`SMILE will establish a GaN cleanroom in order to be completely independent from non-European manufacturers. Customized microLED modules for AR-glasses will be a first product. Beyond that, i`SMILE will be the basis for establishing the worldwide first GaN foundry, making GaN technology fully accessible to European innovators, leading to a “democratisation of microLED technology”. Much like TSMC from Taiwan who is now the world´s largest foundry for silicon CMOS technology, we dream of QubeDot developing into the “TSMC for GaN” in the future. After completion of the project, QubeDot will be able to produce microLED displays and customer-specific microLEDs with the highest precision within its own clean room environment using ISO9001 certified process flows. With single-shift utilization, the pilot line will be able to generate an output translating into potential annual sales of up to 25 M€, with an estimated margin of 30+%. While other very large companies do not adapt their production processes for medium-size batches, QubeDot has understood the interaction of essential parameters in the processing of GaN through intensive research and development work. This enables the production of a wide variety of microLED architectures in terms of quantity, size, shape, emission color and package. While other very large companies depend on semiconductor manufacturers with production sites especially in Asia, or are themselves manufacturing in Asia, QubeDot produces in Europe - at competitive conditions.

Keywords: microled display,microled module,g
Screening metastasis targeting properties of Extracellular Vesicle’s biomolecular corona for Engineering therapeutic biomimetic Nanoparticles (SEVEN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-09-01
End date: 2031-08-31
Duration (months): 60.0
Total project cost (EUR): 1843500.0
EU funding (EUR): 1843500.0
Participants: 1
Project status: SIGNED

Metastasis research is one of the greatest challenges in the medical field. The nanoengineering of inorganic/organic nanoparticles (NPs) with natural signaling carriers such as extracellular vesicles (EVs) is a promising tool to address the lack of treatment efficiency of currently available therapies, blamed on the insufficient accumulation of the antitumoral molecules in the metastasis tissues. Despite several years of intense efforts, therapeutic EVs are still far away from clinical practice. Recent studies have evidenced that this failure is due to the lack of knowledge on how EVs behave in biological environments and how their therapeutic cargo affects the metastasis targeting moieties present on their membranes. Seven believes that the lack of attention on the unknown biomolecular corona (BC) and on its role governing the EVs’ biological identity may well be behind such uncertainties. Understanding EVs’ BC formation will improve the rational EV-inspired nano-therapy design. SEVEN has been designed to generate substantial understating of the NPs-loaded therapeutic EVs behavior, the BC identity and its surface topography to generate new vectors with a much improved accumulation in metastasis target tissues. SEVEN will validate BC’s influence in the EVs metastasis targeting properties in a conceptually and operational ground-breaking experimental design to modify the BC’s surfactome composition for tailoring their therapeutic action. In addition, SEVEN will use supercritical fluid technology as a new scalable and reproducible strategy to create high yield loading of therapeutic NPs-loaded EVs-inspired therapies, maintaining their natural metastasis signaling properties and overcoming the main limitations that have prevented their successful translation to the clinic. All this will allow SEVEN to screen most promising metastasis targeting tailored EVs (loaded with therapeutic NPs) in patient-derived orthotropic xenograft (PDOXs) models.

Keywords: biomolecular corona,extracellular vesicles
Harmonizing Inclusion in Choral Music (InChoir)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Finland
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-01
End date: 2027-12-31
Duration (months): 24.0
Total project cost (EUR): 242116.8
EU funding (EUR): 242116.8
Participants: 1
Project status: SIGNED

Harmonising Inclusion in Choral Music (InChoir) tackles the escalating challenges of inequality, social exclusion, and polarisation in European societies by focusing on inclusive choirs. Whilst culture is promoted as ‘the fourth pillar of sustainability’, and increasing attention has been given to socially-driven music projects in the Global South and Australia, research on socially transformative choirs has remained at the fringes of academia, and little is known about inclusive choir practices in Europe. Whereas music educators and leaders tend to be disconnected from academia, the existing scholarly work typically focuses on a single case or theory. By integrating the disciplines of music, education, and social sciences with the practical expertise of inclusive choirs, InChoir aims to bridge the gap between research on sustainable development and choir practices by producing knowledge on inclusive choir practices in Europe and translating research into practical applications. Three objectives are set: 1) to provide meta-knowledge on reported inclusive choir programs in Europe; 2) to expand reflexive understanding of professional competencies and ethics required for inclusive choirs; and 3) to promote inclusive choirs and music culture in institutional European contexts and the whole-of-society. Through integrating scholarship on inclusive choir studies with a series of individual in-depth (online/onsite) interviews with choral leaders of successful inclusive choir practices in different European countries, InChoir expands and deepens professional understanding in music and provides practical guidelines and policy briefs on the potential of choirs to enhance sustainability. Conducted at one of the leading European music universities under the supervision of a renowned expert in the field, InChoir will exert a significant impact on both academic and practice-based forums of music education as well as on broader society.

Keywords: choir,inclusivity,music education,sustainability,equity,social transformation,musicking,accessibility,diversity
Research on Indigenous Data Governance Protocols: A toolkit for working with Indigenous Knowledge (RIDaGoP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-07-01
End date: 2023-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Data governance trends increasingly emphasize the need to open access to data, despite growing concerns over data privacy, control and surveillance. Indigenous peoples, with different epistemological traditions for the use and sharing of culturally sensitive information, add the additional concern of people’s ability to exert data sovereignty. Thus, while interest grow on the documentation and use of Indigenous knowledge, current data governance trends do not align well with Indigenous data rights and governance rules. This is the case of data on Indigenous peoples’ perceptions of climate change impacts collected under the LICCI project (771056-LICCI-ERC-2017-COG). While adhering to the highest EU ethical standards, data collected under the LICCI project failed to address Indigenous data governance. To develop a set of tools to guide the management of Indigenous knowledge and data in the open while adhering to Indigenous data governance principles, in this project, I will conduct “Research on Indigenous Data Governance Protocols” (RIDaGoP). In partnership with organizations working on Indigenous data governance issues, RIDaGoP will undertake four activities in 18 months: i) a literature review to document Indigenous data governance protocols; ii) an assessment on requirements to operationalize Indigenous data sovereignty in an open context; iii) the development and testing of features to operationalize Indigenous data sovereignty; and iv) the dissemination of results. RIDaGoP will facilitate the configuration and use of Indigenous data sovereignty protocols, allowing knowledge holders to set granular terms of access and use of data and to track data usage. RIDaGoP has the potential to reframe how datasets concerning Indigenous peoples are managed and how Indigenous peoples are represented. Beyond Indigenous data sovereignty, RIDaGoP innovation in tackling equity in data governance can be upscale to issues such as national statistics or health.