Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Homological Invariants of Deformations of Groups and Algebras (HIDRA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 221669.04
EU funding (EUR): 221669.04
Participants: 1
Project status: CLOSED

The pervasive role of algebraic topology in mathematics is proof of the powerful effects that homological invariants produce in the development of the discipline. Extending these techniques beyond the category of topological spaces, in order to include "quantized" systems arising from dynamical systems and (quantum) groups, is going to be extremely useful to make fast progress in these fields. The framework of operator algebras and noncommutative geometry is extremely well-suited for these developments and has already been applied with some success. The goal of this proposal is to further develop these homological techniques by supporting them with novel methods based on triangulated categories, homotopy theory, and index theory. The research problems tackled in this Action are deeply related to important topics which attracted a great deal of interest in the mathematical community. For example, we study the celebrated Baum-Connes conjecture (for both groupoids and quantum groups) through a relatively unexplored perspective and relate it to the computation of K-theoretic and homological invariants for notable dynamical systems (e.g., Smale's Axiom A diffeomorphisms). This research will provide mathematicians with both conceptually new approaches and powerful computational tools. Some of these results are relevant not only for pure mathematics, but also for solid-state physics and quantum information theory. This Action will take us one step closer to the solution of significant problems or the formulation of more and more refined research questions. This fellowship will allow V. Proietti to work under the supervision of M. Yamashita (a world-class expert on quantum groups) at the University of Oslo (a leading institution in operator algebras). It will expand the fellow's technical expertise and integrate it with essential management, administrative, and dissemination skills which will help V. Proietti reach a position of professional maturity.

Keywords: noncommutative geometry,k theory,groupoids,quantum groups,topological dynamics,axiom a systems,smale spaces,triangulated categories,index theory,baum connes conjecture
Discrete Analysis and Quantitative Geometry (DiAnQuGe)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-09-01
End date: 2031-08-31
Duration (months): 60.0
Total project cost (EUR): 1495150.0
EU funding (EUR): 1495150.0
Participants: 1
Project status: SIGNED

This project lies at the crossroads of analysis, geometry and probability theory. DiAnQuGe aims to uncover quantitative properties of geometric objects using techniques from functional analysis, harmonic analysis and probability. Specifically, it is dedicated to the following directions: How well does a given metric space embed in a Banach space or a space with curvature bounds? In Section 1, I propose to investigate the (in)compatibility of the geometries of finite metrics, including expander-like objects and balls of Carnot groups, with Alexandrov spaces of bounded curvature. Based on a well-established analogy with nonlinear Banach space theory, this will require the development of suitable metric invariants, thus forming a link with discrete analysis. On a related direction, I propose a systematic way to develop such invariants for normed spaces, which will serve as a categorical implementation of Bourgain's proposed Ribe program. How does the spectrum of a voting system correlate with the behavior of individual voters? Voting systems are mathematically modeled by functions defined on the vertices of a hypercube in Euclidean space. In Section 2, I propose to utilize input from Fourier analysis, approximation theory and stochastic analysis to further understand the interaction of the spectrum and influences of Boolean functions, along with applications in computer science. How does a high-dimensional convex set look like? In Section 3, I propose to investigate sharp behaviors of isoperimetric profiles of convex sets using a mixture of geometric and probabilistic techniques, with a novel component from calculus of variations. Despite the different origins of these questions, all aforementioned objects share the common feature of having a large-yet-finite dimension, in an appropriate sense. This joint characteristic allows for the transfer of intuition and techniques from one field to the other and has been the driving force behind many recent advances.

Keywords: metric embeddings,ribe program,discrete analysis,geometric functional analysis,convex geometry,high dimensional probability
NEW ROUTES OF SAFE AND SUSTAINABLE BY DESIGN WATER AND OIL REPELLENT BIOBASED COATINGS (TORNADO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Türkiye,France,Sweden
Call: Safe- and sustainable-by-design organic and hybrid coatings (RIA) (HORIZON-CL4-2022-RESILIENCE-01, 2022)
Start date: 2023-01-01
End date: 2026-04-30
Duration (months): 40.0
Total project cost (EUR): 4527891.25
EU funding (EUR): 4527891.25
Participants: 14
Project status: SIGNED

TORNADO project aims to contribute to the transition to a safe circular economy by influencing how products should be designed, produced, used or treated at their end-of-life. New organic and hybrid free-toxic coatings with water and oil repellence following Safe and Sustainable by Design (SSbD) criteria will be developed. The novel proposed coatings will be PFAS free. TORNADO idea is to research and develop 1) Two new type of functionalized acrylated biomonomers with PDMS and POSS by two different chemical routes (acrylation and direct acrylation). 2) To synthesized and formulate 2 new biobased coatings based on the functionalized biomonomers by two technologies, waterborne organic and hybrid coatings and hybrid sol-gel coatings. Biomonomers and coatings will be scale up in an industrial environment. Coatings will be applied by different industrial processes depending on the industrial field. The two coatings will be validated in industrially relevant environments to obtain a performance at least identical to PFAS coatings in terms of water and oil repellence and tested according to the main textile, packaging and kitchenware specifications and requirements (waterproofness, oxygen barrier and durability, respectively). The improvement in environmental performance and circularity of the new coatings will be assessed through environmental Life Cycle Assessment, Life Cycle Cost, and social Life Cycle Analysis (LCA/LCC/s-LCA) of the proposed new coatings compared to traditionally used hazardous coatings. Computational tools will be developed for efficient interfacing with publicly accessible and accepted QSAR-models to facilitate ease-of-use in-silico prediction of required physiochemical properties, toxicological end-points and degradation.

Keywords: safe and sustainable by design ssbd,water and oil repelence,circularity,emulsion polymerization,sol gel,funcionalized biomonomers
Figural Proportions, Guiding Systems and the Drafting of Animals in Ancient Egyptian Tomb Imagery (ANIMATE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-04-01
End date: 2025-03-31
Duration (months): 24.0
Total project cost (EUR): 199440.96
EU funding (EUR): 199440.96
Participants: 1
Project status: CLOSED

Representations of the animal world are an intrinsic feature of ancient Egyptian visual culture. Despite their frequent inclusion in Egyptian imagery, comprehensive analysis of the methods used by practitioners when drafting fauna is lacking, especially when compared to their human counterparts. An example of the existing divide is seen with a central principle of Egyptian art known as the canon of proportion - a work process where guiding systems were used by practitioners to organise a scene and render the correct bodily ratios of a figure. While the use of guides for human figures has been thoroughly investigated, a parallel study for animals has not yet been undertaken due to the untested belief that fauna were not regulated by the same proportional standards. The overarching aim of ANIMATE is to challenge the prevailing perspective of a deregulated approach being in place when illustrating the animal world. The project is driven by three objectives: 1) to determine the rules and ratios governing the design and construction of proportional guides for animal figures via the examination and digital reconstruction of surviving guiding systems from elite tombs of the early Middle Kingdom (c. 2030-1840 B.C.); 2) to demonstrate that the drafting of non-human forms was regulated by investigating parallels or connections between the known techniques used for human proportions and those discovered for drafting animals; and 3) to identify the impact of [external] factors such as biological considerations or scene context on proportional standards for animals and the subsequent design of guides via an incorporation of zoological and zooarchaeological data. By being the first systematic investigation into the design, construction and application of proportional guides for non-human forms, ANIMATE will shift knowledge frontiers by shedding new light on the ‘missing animal’, bringing figures generally perceived as having a secondary status in art into the spotlight.

Keywords: egypt,animals,art,visual culture,canon of proportion,scene composition,drafting,middle kingdom,tomb imagery
Nanoscale Heat Engineering for Advanced Technology (nanoHEAT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 247553.28
EU funding (EUR): 247553.28
Participants: 1
Project status: SIGNED

The miniaturization trend of electronic components down to atomic length scales generates new challenges in the management of heat at the nanoscale. Efficient heat dissipation in electronic devices leads to lower energy waste and improved operation efficiency, thus contributing in a decisive way to environmentally sustainable technological developments. The nanoHEAT project aims to leverage the unique properties of 2D materials for the design of thermally efficient and actively tunable nanodevices, due to their compactness, extraordinary electronic, optical, and thermal properties, and support of exotic polaritons—hybrid light/matter electromagnetic modes that propagate at the surface of materials and play a crucial role in heat transport. Using advanced nanophotonics theory, nanoHEAT will start by studying in detail the behavior of selected 2D materials under extreme conditions of confinement, temperature, and external stimuli (such as magnetic fields or drift currents). After carefully selecting which materials (and their combinations) display the most advantageous thermal capabilities, optimized heterostructures based on these materials and noble metals will be explored as versatile building blocks for realistic setups with enhanced radiative and conductive heat transport in the nanoscale. External stimuli, in combination with other active elements such as quantum scatterers, will be used as knobs to control heat flow in these systems. Carried out at the University of Southern Denmark together with a widely experienced research team, this project will allow the fellow to advance his scientific career by harnessing new skills in nanophotonics, expanding his collaboration network, and acquiring complementary competencies in teaching, communication, and outreach, and research leadership. It will also contribute to solidifying the EU’s strategic position in the photonics industry and paving the way towards new generations of energy-efficient electronic devices.

Keywords: polaritonics,heat transport,thermo optics,thermal engineering,quantum surface effects
Schrödinger bridges to open quantum systems (QBridges)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-01-01
End date: 2026-12-31
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: SIGNED

Quantum systems are inherently stochastic. At the quantum level, randomness is introduced not only through the act of measurement, but also due to the uncontrollable interaction with the surrounding environment. Indeed, the precise manipulation of quantum dynamics presents a challenge for emerging quantum technologies, such as computing, simulation, and quantum sensing. On the other hand, optimal transportation and Brownian/Schrödinger bridges are of central importance in applications requiring regulation and estimation of classical stochastic processes. These include unsupervised machine learning, motion planning in robotics or protein docking and single-cell genomics in biology. In this project, we set out to extend these classical theories into the quantum domain. Specifically, we will develop original methods to regulate and estimate the dynamics of open quantum systems. The research will lead to powerful optimization tools for state steering quantum control of noisy quantum dynamics, and will also provide novel insights into the thermodynamics of stochastic quantum processes. Furthermore, the project will deliver new methods to characterize the dynamics of complex quantum systems that better fit experimental observations, thus making a groundbreaking contribution to the theory of open quantum systems. Overall, this research will bridge the gap between mathematics and the next generation of quantum technologies, which will have broad implications, from quantum thermodynamics to quantum sensing or coherent control.

Keywords: open quantum systems,stochastic quantum dynamics,weakly measured quantum systems,schr dinger bridges,diffusion bridges,optimal transportation
Investigating if recuperating hepatic macrophage numbers and functions in chronic fibrosis can limit the incidence and severity of infections (ReKUPFFERate)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-01
End date: 2025-09-30
Duration (months): 24.0
Total project cost (EUR): 175920.0
EU funding (EUR): 175920.0
Participants: 1
Project status: SIGNED

Liver fibrosis is the build-up of scar tissue resulting in impaired liver function. It can have different causes including alcohol abuse, obesity and viral hepatitis. For reasons that we do not fully understand, patients with fibrosis (termed cirrhosis) are more susceptible to infections. In fact, 50% of hospitalized patients with liver cirrhosis and infection die, highlighting the scale of this problem. Macrophages (MFs) are immune cells present in every tissue of the body that function to eliminate pathogens. In the liver, one subset of MFs, the Kupffer cells (KCs) are perfectly equipped with scavenger and pathogen recognition receptors to do this. Moreover, they are positioned in the bloodstream meaning they are one of the first cells to sense and respond to circulating pathogens although their precise roles have not yet been elucidated. In cirrhosis, KCs are reduced in number, being replaced by distinct MF subtypes, including a population termed lipid-associated MFs (LAMs). Preliminary data from the host lab demonstrate that both KCs and LAMs from the cirrhotic liver respond less efficiently to infection when compared with their healthy counterparts. Thus, I hypothesize that the altered MF landscape in cirrhosis and fibrosis is one mechanism driving the increased susceptibility and exacerbated responses to infection in these patients. Here, I aim to test this hypothesis by examining how the different MFs respond to infection in the presence and absence of fibrosis. Using novel mouse models specifically targeting the distinct MF populations, coupled with ex vivo cultures of human hepatic MFs, I will tease apart the mechanisms through which MFs exert their effects and attempt to manipulate these to recuperate normal MF numbers and functions potentially uncovering novel therapeutic approaches to limit infection and improve cirrhotic patient health.

Keywords: macrophages fibrosis cirrhosis infection macrophage niche liver kupffer cells lipid associated macrophages lps
Environment-Mediated Genetics: The Power of Biological Non-Determinism for Mental Health (EM-POWER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-05-01
End date: 2030-04-30
Duration (months): 60.0
Total project cost (EUR): 1997169.0
EU funding (EUR): 1997169.0
Participants: 1
Project status: SIGNED

Mental health problems are associated with variation in the brain and genome. The mechanisms underlying these associations are extremely hard to discern because they are subtly distributed across thousands of genes and not specific to neural processes. Meanwhile, a focus on biology tends to induce feelings of helplessness among those affected by mental health problems, as biology is typically seen as deterministic. I propose that both our mechanistic understanding and the sense of personal agency will leap forward if we consider modifiable, heritable social and lifestyle factors (i.e. "environment") centrally within the causal chain from genes to brain to mental health. Environmental factors are known to be heritable, yet a bottom-up gene-brain causal model prevails due to its intuitive and practical appeal. Standard methods are limited to pairwise associations between the many relevant genetic, brain and environmental variables. The heritable environment is thus hard to account for, let alone embrace as an opportunity. We developed a new multivariate method that can identify patterns of shared genetic effects across thousands of variables. By combining this method with genetically informed causal models and family designs, we will reveal the overall explanatory power and pervasiveness of environment-mediated genetic influences on brain and mental health. We will further characterise these to identify which environmental factors are potential mediators of genetic influences on brain and mental health, when they emerge, and if and how they are personally modifiable. The goal of EM-POWER is to lay empirical foundations for a new non-deterministic biological paradigm, that leads to new mechanistic insights of environment-mediated biological mechanisms, within this project and beyond. The future outcome is that people know the potential of personal control over biological factors and can break causal chains from genetic vulnerability to mental health problems.

Keywords: gene environment correlation mental health well being transdiagnostic psychiatric genetics behavioural genetics neuroimaging genetics multifactorial genetics neurogenetics biological psychiatry
RECONFIGURABLE SUPERCONDUTING AND PHOTONIC TECHNOLOGIES OF THE FUTURE (RESPITE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands,Belgium,Türkiye,Germany,United Kingdom
Call: EIC Pathfinder Open 2022 (HORIZON-EIC-2022-PATHFINDEROPEN-01, 2022)
Start date: 2023-03-01
End date: 2027-02-28
Duration (months): 48.0
Total project cost (EUR): 2455823.25
EU funding (EUR): 2455823.25
Participants: 7
Project status: SIGNED

Computing with light using integrated optics has seen huge progress over the last 3-4 years in multiple fields such as neuromorphic computing, quantum computing and on-chip data storage. This has created a vast ecosystem that relies on high-speed reconfigurations of nanophotonic circuits (such as their use as synapses or routing applications) and ultrafast yet high-resolution, low-power photodetection. Currently, it is impossible to combine all these functionalities into an integrated platform that fits onto a single chip. In RESPITE, by utilizing our newly invented superconducting Joule switches as neurons, multi-level phase change memory elements as synaptic weights, and superconducting single-photon detector arrays as retina we will demonstrate a novel platform which combines vision and cognition on a single chip. This new platform will allow in-sensor neuromorphic computing with unprecedented performance levels. The platform will have attoJoule switching power consumption, sub-nanosecond latency, and high compactness (3000 neurons and >100K synapses on <5 mm2). Unlike other superconducting neuromorphic technologies, our new platform will be scalable, easy to fabricate, and compatible with low-cost cryostats, high-Tc superconductors, quantum applications, and on-chip learning architectures – making it a game changer for a wide range of users and disciplines.

Keywords: nano photonics,neuromorphic computing,superconducting devices