Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Hybrid Electric propulsion system for regional AiRcrafT (HE-ART)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Aviation
Action type: Innovation actions
Partnership: CLEAN-AVIATION (JU-JTI)
Countries involved: Germany,France,Italy,Spain,Norway,Poland,Belgium,Romania,United Kingdom
Call: Multi-MW Hybrid-Electric Propulsion System for Regional Aircraft (HORIZON-JU-Clean-Aviation-2022-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 73856266.74
EU funding (EUR): 44103443.0
Participants: 38
Project status: SIGNED

Air travel is an important supplement to other means of regional transportation and in some regions the only viable solution. However, the regional transport market is highly competitive, and air travel must demonstrate that it can compete with hi-speed trains, cars or coaches. One major issue is the perception of the high CO2 and greenhouse gas (GHG) emissions by planes for these short journeys. Hybridization of the propulsion system enables combining the technical components benefits, thereby achieving an overall efficiency improvement. It is a concept well understood by the general public, due to the hybridization of automobiles, and can bring a real impact on the reduction of GHG emissions. While enabling rather than limiting new sources of energy in aviation, an ambitious path to reduction of greenhouse gases and the pathway to a cleaner and greener aviation for regional flights is built upon three pillars: • Electric hybridization • An ultra-efficient turboprop thermal engine • 100% SAF compatibility HE-ART will be a first step on the path to hybridization of regional aircraft and a reduction of up to XX% of GHG. This will be accomplished by achieving a strategic global objective of demonstrating, within 36 months, the viability of a hybrid electric thermal turboprop (e-TP) within the scope of a dedicated integrated ground test demonstrator. HE-ART will build on existing state of the art integrating the following technologies into the demonstrator: • Core thermal engine • Electric motor and power electronics • Gearbox • Propeller • Nacelle and heat exchanger This will be executed in conjunction with the Top-Level Aircraft Requirements that will be defined in parallel Clean Aviation research projects. To ensure that these requirements are met in full, HE-ART brings together the leading engine manufacturers, Rolls Royce and Safran with leading airframers, ATR, Airbus and Leonardo along with key manufacturers and research organisations.

Keywords: turboprop,e tp,heps,regional aircraft,advanced propeller
Multidimensional Hyperentangled Photon Graph States: Creation, Validation and Application (HyperGraph)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-12-01
End date: 2030-11-30
Duration (months): 60.0
Total project cost (EUR): 2515938.0
EU funding (EUR): 2515938.0
Participants: 1
Project status: SIGNED

At the heart of quantum physics and quantum technology lies the captivating phenomenon of entanglement, which society hopes to profit from in improved and completely novel technical applications within the second quantum revolution. Entangled quantum states are extremely difficult to create and validate; only 50 years ago entangled states were shown to violate Bell’s inequalities, using two entangled quantized states of electromagnetic radiation, known as single photon states. For this achievement the 2022 Nobel Prize in Physics was awarded. Ever since, entangled states have driven fundamental and applied research. Intriguingly, entanglement can theoretically be created between an arbitrary number of photons. Their creation, however, has been very challenging, and over the past years, the size of one-dimensional entangled photon states has been increased to 14 in 2022. The slow progress is mainly limited by the development of deterministic single photon sources. Recently, I have designed a novel spin-photon interface in diamond with record-high emitter to detector efficiencies theoretically exceeding 99% and realistically reaching 90%. These record efficiencies are enabled by the Sawfish interface. Multiplexing of several of such interfaces will enable the creation of large 2D and even 3D photon graph states. These states will be so complex, that new theoretical models are required for their understanding. The usage of states whose density matrix could never be computed on classical computers is indeed a conceptual problem in theory. In this regime, HyperGraph’s experimental research will stimulate concepts and new discoveries in theory. Moreover, because of the many degrees of interconnection between the individual qubits, I expect innovative concepts for error correction, novel and possibly improved protocols in fault tolerant quantum information processing, and even completely new application cases to be developed in parallel and beyond HyperGraph.

Keywords: quantum states of light,entangled photon states,entanglement generation,color centers in diamond,diamond nanocavities,nanophotonic spin photon interfaces,feedforward operations,error correction,photon graph states,hyperentanglement,hyperentangled photon graph states
Strengthening excellence for advanced osteosarcoma’s predictive models (PREDICTOS)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Portugal,Italy,Netherlands,Belgium
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2023-01-01
End date: 2026-03-31
Duration (months): 39.0
Total project cost (EUR): 1375187.5
EU funding (EUR): 1375187.5
Participants: 4
Project status: SIGNED

Discovering newest and enhanced forms to analyse and treat cancer is among the top national and international priorities (e.g. HEurope’s Mission on Cancer; Europe’s Beating Cancer Plan). PREDICTOS focus on the enhancement of the scientific and innovation excellence of CDRSP-PL (widening partner, PT) aiming at the exploration and development of innovative solutions for an improved treatment of osteosarcoma (OS) (the tumour that most affects the youngest, with lower cure success). By cooperating with three leading institutions (CNR, IT; MERLN, NL; ULIEGE, BE), this project will encompass various knowledge sharing and capacity building activities (e.g., short staff exchanges for researchers and management/ administrative staff; networking events and meetings; training sessions; organization of workshops, summer/winter schools; coaching and mentoring sessions gathering senior and junior researchers; publication of scientific articles, and participation in conferences and general public’s events. Also, the consortium will collaborate in an exploratory research project for develop and test 3D in vitro and in silico models to mimic OS, generating knowledge on novel therapeutic strategies to eliminate cancer cells. PREDICTOS expects to benefit directly +400 senior and junior researchers and administrative staff from partners’ institutions, to involve +80 relevant stakeholders from Academia, Industry and Policy-Making in networking activities and to reach +10.000 individuals through dissemination and communication activities. PREDICTOS is, in this way, aligned with the expected outcomes and impacts from Twinning Call and Destination, contributing to bridge the research and innovation gap between the European entities, improve research management and administrative skills, raise entities reputation and research excellence, and stimulate institutions to join efforts and co-innovate and establish more strategic research approaches and cooperation.

Keywords: biomanufacturing,biomimicry,in vitro,3d digital technology,in silico,magnetic stimulation,osteosarcoma,cancer,therapy,coaching and mentoring,capacity building,innovation ecosystem
HDHL Food4Health (HDHL F4H)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Reforming and enhancing the European R&I System
Destination: Reforming and enhancing the European R&I System
Action type: Coordination and support actions
Countries involved: Netherlands,Belgium,France,Romania,Lithuania,Latvia,Italy,Serbia
Call: Programme level collaboration between national R&I policy-makers (HORIZON-WIDERA-2024-ERA-01, 2024)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 2414977.5
EU funding (EUR): 2414977.5
Participants: 11
Project status: SIGNED

HDHL Food4Health addresses the intertwined challenges of food and diet-related Non Communicable Diseases (NCDs) and Climate Change by fostering collaboration and aligning research efforts across food, health, and environment areas. Through a participatory approach, HDHL Food4Health widens the HDHL network and organises co-creation workshops to identify common Research & Innovation (R&I) priorities. It aims to overcome siloed approaches by coordinating activities among government, academia, industry, and citizens, enhancing societal impact at national and regional levels. Leveraging its connections with researchers, policymakers, and other relevant stakeholders, HDHL supports its members in contributing to the Sustainable Development Goals (SDGs) by aligning food and health systems. The initiative facilitates joint funding calls and implements transdisciplinary research actions to maximise impact and address urgent societal challenges. By promoting collaboration and knowledge exchange, HDHL Food4Health aims to catalyse a shift towards healthier and more sustainable food systems, ultimately contributing to improved public health and environmental sustainability. The main objective of HDHL Food4Health is to align common R&I priorities among funding programmes by identifying research and policy needs, whilst continuing to align both with the Horizon Europe (HE) Partnerships and the needs identified by the European Commission.

Keywords: nutrition,transnational cooperation,research and policy coherence,health,food systems,alignment,stakeholder engagement
Attention on inattention: Dissecting the causal mechanisms of adult ADHD features (AT-TENSION)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Estonia
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1499750.0
EU funding (EUR): 1499750.0
Participants: 1
Project status: SIGNED

The world is witnessing a sharp rise in adult attention deficit hyperactivity disorder (ADHD) diagnoses, especially after the COVID-19 pandemic. While historically considered a childhood neurodevelopmental disorder, an increasing number of adults are now seeking help for impairing ADHD-like features like inattention, disorganization, restlessness, impulsivity, forgetfulness and emotional dysregulation. Strikingly little is known about the mechanisms causing specific adult ADHD features, raising a key question: Are adult ADHD features truly the same as childhood ADHD, or do they rather reflect other mental conditions with overlapping symptoms? Substantial phenotypic overlap of mental health conditions and lack of precise screening tools make accurate detection of adult ADHD extremely challenging and error prone. Modern mental health care critically needs advanced, biology-informed methods to differentiate mental conditions with greater accuracy. AT-TENSION combines psychology, genomics and data science to dissect the causal mechanisms underlying adult ADHD features and to propose an innovative framework for genomics-informed screening tool development. We will (i) determine diverse genetic mechanisms and causal links with other mental conditions by conducting a pioneering genome-wide investigation of specific adult ADHD features across five large biobanks; (ii) quantify the impact of diverse environmental factors like stress, lifestyle and COVID-19 pandemic on adult ADHD features across life stages and genders; (iii) develop and test a novel genomics-informed screening tool for more accurate ADHD detection in adults by using machine learning and genomics. The goals are achieved by innovatively combining three large-scale data layers: self-reported, electronic health records and genetic data. AT-TENSION aims to redefine our current conceptualization of adult ADHD and revolutionize mental health psychometrics by integrating genomics into screening tool development.

Keywords: mental health,adult adhd,screening instruments,psychiatric epidemiology,psychiatric genomics,stress,covid 19 pandemic,data science
SUstainable nanoPaRticles Enabled antiMicrobial surfacE coatings (SUPREME)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Greece,Belgium,Netherlands,Italy,United Kingdom,Norway,Spain,Portugal
Call: Antimicrobial, Antiviral, and Antifungal Nanocoatings (RIA) (HORIZON-CL4-2021-RESILIENCE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 4737523.75
EU funding (EUR): 4737523.75
Participants: 19
Project status: SIGNED

The catastrophic ongoing pandemic has attracted our attention towards the spread of harmful pathogens facilitated by high traffic surfaces, highlighting the importance and urgency of an economically and environmentally sustainable solution for antimicrobial surface as a potential strategy to mitigate the spread of disease outbreaks. Nanoparticle (NP) filled coatings, with recognised effectiveness against bacteria, viruses, and fungi, are valuable candidates for developing antimicrobial surface and minimising the surface adhesion of pathogens. However, due to the many technical challenges, including difficulty to develop nanocoatings with a long-term antimicrobial capability, durability under real conditions and safety assurance, their application at industrial level is still limited. The SUPREME consortium will develop a platform of efficient and multifunctional antimicrobial nanocoatings, building upon bespoke TiO2 nanoparticles that have demonstrated an exceptional antimicrobial ability at lab scale (TRL3). Two sustainable routes: 1) customised core/shell and advanced functional nanoparticles and 2) hybrid fibre-nanoparticles (using sustainable bio-based cellulose materials and nanoparticles) will be pursued. Bearing in mind the specific requirements of individual applications, the SUPREME consortium will coordinate the antimicrobial testings to its effectiveness against a wide range of pathogens. The production of the SUPREME coating will follow a sustainable-by-design approach that considers both toxicity and environmental impact from outset to guarantee both market acceptance and sustainability of the overall process whilst having a robust safety assurance in place for human health. The scaling-up production of these sustainable materials and their validation according to the industrial requirements will enable to reach the TRL6 by the end of the project.

Keywords: nanoparticles,hybrid fibre nanoparticles
Mechanical torsional oscillations driven by the angular momentum of light (OSCILLIGHT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-05-01
End date: 2025-04-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: CLOSED

The ability of light to carry angular momentum has been the subject of an active scientific research since the beginning of 20th century, and yet the knowledge in this area still has many gaps and overlooked possibilities for technological innovation. In particular, a non-dissipative technology enabling an optomechanical transduction of the angular momentum irrespective of its spin or orbital nature is yet to be achieved. The project “OSCILLIGHT” offers an original solution to this problem by exploiting the inherent vector nature of angular momentum. During the two-year fellowship at University of Bordeaux (France), Dr. Georgiy Tkachenko (Researcher) guided by Dr. Etienne Brasselet (Supervisor) will realize proof-of-concept experimental demonstrations of the universal transfer of angular momentum that will lead to the implementation of a mechanical oscillator, whose size will eventually make it compatible with on-chip photonic systems. This work will therefore answer the key strategic orientation of the European Commission towards the development of digital, enabling and emerging technologies for micro/nanoelectronics and photonics. The proposed research is timely, as the scientific literature over the last 5 years has seen the increasing emergence of studies on integrated optomechanical devices, including those driven by angular momentum of light. After the last few years of the relevant preparatory work done by the Supervisor, his students and collaborators, the stage is now set for an effective implementation of this proposal, and the Researcher is the perfect candidate for the leading role to be played under the Supervisor’s guidance. Most importantly, the successful realization of this project will be beneficial to both the host university and the Researcher’s career path to securing a stable academic position and eventually leading his own research group.

Keywords: angular momentum,optical manipulation,torsional mechanical oscillator,resonance,structured light
Reinforcement learning to improve proof-automation in theorem proving (DeepIsaHOL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Czechia
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-07-01
End date: 2025-10-31
Duration (months): 28.0
Total project cost (EUR): 166278.72
EU funding (EUR): 166278.72
Participants: 1
Project status: SIGNED

Developing generic proof automation methods for interactive theorem provers (ITPs) is challenging but valuable. Applications range from performance improvements in the verification of safety-critical systems to the certification of famous, long, and hard-to-prove theorems. We propose using recently successful reinforcement learning (RL) algorithms to learn proof strategies employed in vast ITP libraries and use them as generic methods to automate the ITP proving process. Specifically, the project aims to create a tactic for one of the most popular and automated ITPs, Isabelle/HOL, and train the RL algorithms with theorems from the two largest Isabelle libraries: HOL-Library and the Archive of Formal Proofs (AFP). We identify three gaps in the state of the art that such an RL-and-Isabelle approach would close and describe the work packages that will achieve the corresponding three research objectives. The project will be done under the guidance of Dr Josef Urban, who holds a Distinguished Researcher position at the Czech Institute of Informatics, Robotics and Cybernetics (CIIRC) within the Czech Technical University (CTU) in Prague. Dr Urban and the CIIRC group are experts in integrating machine learning (ML) and interactive theorem proving. Their infrastructure and expertise targeted to ML and ITPs provide the best research environment for this project. Jonathan Julián Huerta y Munive, the researcher carrying out the project, complements this expertise with his Isabelle/HOL experience and knowledge of ITP applications.

Keywords: deductive verification,reinforcement learning,interactive theorem provers
Cryo-CLEM in situ imaging of adenovirus stepwise disassembly (CryoCLEMAV)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-01-16
End date: 2026-01-15
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: SIGNED

Adenoviruses (AdVs) are very contagious viruses widespread in vertebrated. Human AdVs infections mainly affect children and immune-supressed people. On the other hand, AdV-derived vectors, nanocarriers and vaccines have turn out to be efficient therapeutic tools. Understanding AdVs disassembly mechanisms is vital to advance research in antiviral drugs, gene therapies, nanocarriers and vaccines. AdV particles’ metastability is key for surviving environmental conditions and cell defences, but at the same time, these particles should disassemble at the appropriate time and place during virus entry. The particle size and the speed of the process challenges the visualization of these events inside the cell. CryoCLEMAV aims at providing unprecedented structural insight on the process of virus entry and disassembly by combining virology with the cutting-edge microscopy techniques: correlative light and electron microscopy (cryo-CLEM), cryo-electron tomography (cryo-ET), FIB-milling and subtomogram averaging. This approach will allow to recapitulate the process with a previously unreachable resolution and specificity in a near native context of the host cell. CryoCLEMAV is an ambitious project whose success will be firmly supported by merging my expertise in virology and super resolution microscopy with the host lab knowledge and resources in cryo-EM techniques and adenovirus biology. Outcomes of this project will contribute to the development of several cryo-electron microscopy techniques and to the field of adenovirus biology, also impacting in the expanding field of adenovirus-derived therapeutic tools. All together will advance the research work of my host group, benefit the host organization (CNB-CSIC), and boost my professional career.

Keywords: cryo electron microscopy,adenovirus,disassembly,cryo clem,cryo et,tomogram,3d reconstruction