Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Restoring Mueller glia cell – photoreceptor interactions with Crumbs (CRUMBS IN SIGHT)

Framework: FP7 — Cooperation
Programme: Health
Destination: Translating research for human health
Action type: Collaborative project
Countries involved: Netherlands,Germany,Germany,France,United Kingdom,Netherlands
Call:  (FP7-HEALTH-2007-A, 2007)
Start date: 2008-04-01
End date: 2012-05-31
Duration (months): 50.0
Total project cost (EUR): 3969345.2
EU funding (EUR): 2999900.0
Participants: 7
Project status: CLOSED

Mutations in the Crumbs homologue 1 (CRB1) gene cause photoreceptor degeneration resulting in progressive retinitis pigmentosa (RP) or Leber congenital amaurosis (LCA), which both currently are untreatable blinding diseases. CRB1 is localized in Mueller glia cells at a subapical region (SAR) adjacent to adherens junctions between Mueller glia cells and photoreceptors. Loss of CRB1 function results in loss of adhesion between Mueller glia cells and photoreceptors. This ultimately results in the death of photoreceptors and other retinal neurons with loss of vision at birth (LCA) or before the age of 20 years (progressive RP). Using fruitfly and mouse genetics we will analyze the biochemical, cellular, developmental and physiological functions of CRB1, its family member CRB3, and CRB1-interacting-proteins PALS1, PATJ and MUPP1, in function of the SAR and its role in cell-cell interactions. We will analyze the effect of loss of interaction between Mueller glia cells and photoreceptors and subsequent retinal degeneration in retinas lacking both CRB1 and CRB3, or lacking the CRB1-interacting protein PALS1. To further understand the role of these proteins in neural-glial interactions in general, we will also assess what role these molecules play during development. To develop a cure restoring the impaired interaction between glial cells and photoreceptors, we will explore the efficacy of Mueller glia progenitor cell transplantation in mouse retinas. In collaboration with a small enterprise we will also deliver clinical grade adeno-associated viral (AAV) gene therapy vectors to transfer and express human CRB1 specifically in Mueller glia cells lacking CRB1 function. At the end of the project we will develop a demonstration project using these vectors in clinical phase I/II tests.

Keywords: mueller glia cell,neuron,photoreceptor,interactions,retina,disorganization,degeneration,blindness,crumbs
ILE DE FRANCE FRENCH EUROPEAN RESEARCHERS' NIGHT: IF I WERE A RESERACHER,.... (IDFFERN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: France,France
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-06-01
End date: 2008-02-29
Duration (months): 9.0
Total project cost (EUR): 86412.0
EU funding (EUR): 55000.0
Participants: 7
Project status: CLOSED

Researchers’ Night 2007 in Ile de France (IDFFERN) : if I were e researcher…” aims at giving the opportunity to a large public to meet researchers outside their laboratories. This federative project that brings together 9 partners (local authorities, networks of associations, research structures, SMEs and universities) will result in a festive night all over the territory of the Ile-de-France Region. The project will be linked with other events taking place in France at the same time. The large public will be invited to put themselves in a researcher’s shoes through a variety of captivating activities dedicated to different age categories (children, young and elderly people;..) : scientific theatre, pedagogic activities, demonstrations… The activities have a funny and fascinating side but also raise awareness of the participants on sustainable development of the region and other social issues. They will encourage the idea that every citizen can play an active role in science making. Researchers will be invited to unveil and share their passion with the public in the nice relaxed atmosphere of public gardens, bars and restaurants, theatres and libraries. They will also have the occasion to prove the young public that European research domain offers multiple career possibilities. Several communication channels will be used to disseminate the information all over Ile-de-France (web site, newspapers, radio…). A film will result from the night that will be broadcasted on internet. Further to the event, the IDFFERN consortium will launch new projects, benefiting from this innovative experience of festive events to raise the interest of the public in scientific issues.

Keywords: researchers science - fun - ile-de-france - science and society - region - youth - science theatre - drawing competition
Hot and Cool Science - Researchers' Night 2007 in Mainz (HACS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Germany
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-06-01
End date: 2007-12-31
Duration (months): 7.0
Total project cost (EUR): 110959.0
EU funding (EUR): 72000.0
Participants: 4
Project status: CLOSED

On 28 September 2007, the University of Mainz, the Max Planck Institute for Chemistry and the State Ministry for Education, Research, Youth and Cultural Affairs – with the technical support of TVL Ritter Veranstaltungstechnik – plan to stage a Researchers’ Night with the motto "Hot and Cool Science". Aim of the event is to celebrate science and researchers, while introducing a broad public to the unique research and learning environment in Mainz. To highlight the focus on researchers as people, the evening will allow a broad range of opportunities for the public to meet and communicate with scientists, including e.g. fireside conversations and a “Hot & Cool Café” staffed by researchers. The public will be able to experience science in a range of hands-on activities – guided lab tours, tours of the outstanding research facilities in Mainz, and hands-on experiments. Indoors, a host of research projects will explain their activities at dedicated project stands, while offering interactive elements such as quizzes, competitions and try-out features. The same area will comprise a European stand, general information, and the exhibition of works of art entered into the Drawing Competition “Draw a Researcher”. Several fascinating projects shall be introduced on an outdoor central stage, where the audience can also enjoy the awards ceremony for a drawing competition and musical and cultural highlights having to do with and/or performed by researchers. Light effects and catering around the central stage will round off the festive atmosphere. To attract as many visitors as possible, the event will target different audience groups with a broad range of highlights and activities, and will be widely advertised in all media outlets. During this process, the awareness campaign will be able to harness the impact of other public outreach events carried out by the University. The quality and impact of the Researchers’ Night will be estimated in a comprehensive impact assessment.

Keywords: celebrate science - raise researchers profile - researchers and society - public entertainment - public education
Searching into the past looking at the future (PASTANDFUTURE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Italy,Italy
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-06-01
End date: 2007-12-31
Duration (months): 7.0
Total project cost (EUR): 79670.0
EU funding (EUR): 67265.0
Participants: 7
Project status: CLOSED

Last year Dicocom organized the Neapolitan researchers’ night in the ancient centre of Naples,with the VEGAN project.This year we want to follow the same approach to give continuity to the event, also because we’ld like that the researchers’ night turn into a fix appointment for Naples, for this reason we decided to focus our project on the research between the past and the future and propose the same location:piazza Dante.Our project is based on the binomial research in the past/research for the future,we have from one side all the disciplines linked to archaeology,conservation and promotion of cultural heritage and the re-proposal of last year simulated excavation for children. In this context we intend to twin the event with others in the domain of cultural heritage: the exhibition realised in the frame of a Culture2000project and the launch of the ancient monastic complex of Cimitile.The other side is represented by scientific research focused on the future, in this context we tried to collect all the main Campanian research centres, from Universities to the CRC to the CNR to the National Astrophysics Institute to the association “women in research”organised.Moreover we will organise the Competition Draw a Researcher with an exhibition that will be held in the Monastic Citadel of Suor Orsola Benincasa University and another in the monastic complex of Cimitile.The main objective of this researchers’ night is to realise an event focused on the discovery,the fun and stay all together,with the maximum of participation to give to Neapolitan researchers the occasion to go in “piazza” and celebrate!Our aim is that researchers have an occasion to play with their knowledge involving people, to talk and dialogue with them to share their passion, that the researchers could demonstrate to everybody throughout scientific, amusing and divulgation activities that the research work doesn’t alienate, doesn’t isolate doesn’t get people like laboratory rats,at the contrary

Keywords: astrophisicics optic vulcanology environment biotecnology molecolar diagnostic genomic archaelogy conservation restore drawing
Researchers' Night in Latvia (NIGHTLV)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Latvia,Latvia,Latvia,Latvia
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-08-01
End date: 2007-11-30
Duration (months): 4.0
Total project cost (EUR): 66930.0
EU funding (EUR): 62730.0
Participants: 9
Project status: CLOSED

The main objectives of the Researchers’ Night are to familiarize larger public, especially young people, with the scientist’s profession; to show the impact of sciences such as chemistry, medical science, biochemistry, physics, on everyday human life; to show researchers as ordinary people; to bring researchers closer to the Latvian society and to attract more young people to research careers. The aim of the activities is to enhance public recognition of researchers and their role in Latvian society. There will not be a strict thematic priority to the Researchers’ Night, although most of the fields covered will be directly or indirectly related to human health – life sciences, biology, biochemistry, pharmaceutical industry, food research, etc. It will be achieved by organising a series of attractive events in three towns - Riga, Daugavpils and Jelgava – all important research centres of Latvia. The project will be realised by joint efforts of 4 Universities, Ministry of Education and Science, 2 research institutes, 1 researcher’s support organisation and 1 professional association. The Researchers’ Night will be preceded by a promotional campaign in mass media. The scope of activities will include a drawing competition among children, establishing a European stand, organising a Café Scientifique; scenic plays performed by researchers; holding public meetings with Marie Curie scholarship holders; arranging a series of events with scientific experiments in research institutes and universities. An opinion survey will be performed to size up the viewpoints of general public on researchers’ profession, evaluate the impact of the event and collect ideas for future activities. The event will be documented in video-film for further demonstration in TV, other events and schools.

Keywords: popular science,public events,science communication
Silene floral and deterrent signals (FLORDETERSIGNALS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Poland
Call:  (FP7-PEOPLE-2007-2-2-ERG, 2007)
Start date: 2007-10-01
End date: 2010-09-30
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

Globalization has resulted in the transport of species around the world. Humans have removed many of the typical barriers and have increased the movement of species overall. Among these transported species, some have been identified as having substantial negative economic ecological impacts. Protecting crops against insect pest using environmental-friendly practices is a growing concern in Europe. This concern led the European commission to re-evaluate and limit the use of pesticides on all crops. Biological control agents have the potential to significantly reduce pest populations. The main research idea for this project is to look at herbivore iduced floral odor changes and their evolutionary dynamics in Silene. This is of special inerest since in this plant, one of the main herbivores is also a pollinator (Hadena bicruris). Thus there should be a fundamental trade-off for the plant, either to invest in pollinator attraction, or avoid herbivore attack. The net impact of Hadena on the fitness of Silene depends on the availability of other pollinators. If co-pollinators are frequent and efficient, Hadena will act as an antagonist, but if co-pollinators are missing, Hadena will be a synergist. In this project, the applicant proposes to analyze volatiles released by Silene plants in response to Hadena seed consumption, and compares these induced responses in multiple populations, to learn about evolutionary dynamics of this system. The applicant suggests focusing more on the evolutionary side of the story. One of the main question is how do induced responses in plants evolve, and how flexible is this system? This is quite a novel question, and it has not at all been introduced in pest management. In this project, the applicant proposes to analyze volatiles released by Silene plants in response to Hadena seed consumption, and compares these induced responses in multiple populations, to learn about evolutionary dynamics of this system.

Keywords: natural sciences
Researchers' Night 2007 in Poland (RESEN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Poland
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-07-01
End date: 2007-12-31
Duration (months): 6.0
Total project cost (EUR): 54439.0
EU funding (EUR): 40000.0
Participants: 2
Project status: CLOSED

The main objective of the project „Researchers’ Night in Poland” is to bring the researchers closer to the large public by showing their significant role they play in society, particularly within the citizens’ daily life. The implementation of the project will contribute towards showing to the large public the attractiveness of the scientific profession and their relevance in creating knowledge-driven society. This will be achieved by organising a set of events taking place during the night on 28 Sept. 2007. As a result of the project, the researchers will be perceived as “ordinary people” to which the public can identify itself, wiling to share their passions for research with every citizen in Europe according to the saying: “Researchers are among us”. In particular it is expected that the implementation of the project will convince young people that scientific careers can be fascinating and stimulate their embarkation on scientific orientations. The project will also have an influence on developing favourable conditions for scientific environment, also increasing Europe’s attractiveness as a place for conducting scientific career. Achieving the projects objectives will be possible thanks to organising such relaxing activities as: hands-on experiments conducted by researchers, scientific demonstrations realised by researchers with public participation, guided visits of labs, real scientific experiments handled by the public, workshops, quizzes, etc. The project’s duration is 6 months. It will be divided into three main phases. During the first phase an awareness campaign will be organised aiming at informing about the Researchers’ Night as large a target as possible. The second phase concerns activities taking place during the night itself. The third phase will concentrate on impact assessment activities allowing a reliable assessment of the actions’ impact regarding the public image of the researchers and their recognition.

Keywords: reserchers,large public,interactive activities
RESEARCHER'S NIGHT, COPENHAGEN Meet science in art, music, food and drink (RNC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Denmark
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-05-01
End date: 2007-11-30
Duration (months): 7.0
Total project cost (EUR): 176066.0
EU funding (EUR): 69769.0
Participants: 1
Project status: CLOSED

Researcher's Night will be celebrated on Sep. 28th in Copenhagen, Denmark as the conclusion of the Week-long Danish Science Week. The event will take place at the Town Hall Square and involves • hands-on exhibits (from Sept 24th to Sept. 28 • a special Friday Night Event with focus on science in art, music and • the Finals of the Draw a Scientist national competition The objective is to make science accessible to an audience of young people between 15 and 30, who will be in town on a Friday night. The researchers presenting the activities will themselves be young, most of them PhD students, thus stimulating a dialogue between the presenters and the audience. By using popular music performers and offering interesting activities involving food and drink, a large young audience is expected to participate, and the unusual approach to science communication is also expected to attract a lot of press coverage. The young scientists comes from different universities in the Copenhagen area. These universities have collaborated making big exhibitions of this kind in 2002, 2004 and 2006. The activity is planned by Danish Science Communication (DSC), a non-profit organisation with 10 years of experience in doing science events in cities, railway stations, rock festivals and so on. DSC is a co-founder of EUSCEA, the European Science Events Association.

Keywords: science communication young people teenagers art music food copenhagen
Belgian Researchers’ Initiatives to Heat That NIGHT 2 (BRIGHT NIGHT 2)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Belgium,Belgium,Belgium
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-06-01
End date: 2007-11-30
Duration (months): 6.0
Total project cost (EUR): 347629.0
EU funding (EUR): 170000.0
Participants: 6
Project status: CLOSED

On the 28th of September 2007, four big events will be organised in three Belgian cities in the frame of the European Researchers’ night. Six partners have joined their forces in a consortium coordinated by the Belgian Federal Science Policy (BELSPO), including four of the biggest Belgian universities and four federal scientific Institutes merged for the occasion in a unique Space Pole. All partners agreed on a common publicity campaign, a common communication and last but not least; a common theme Save the Planet, putting forward very actual branches of Sciences (Climatology, Geology, Astronomy,...) but leaving space for other disciplines to get connected. Next to this, freedom has been given to the partners, so the Belgian researchers’ night will be the unique opportunity to see a Fashion show with recycled items, followed by a fantastic concert in Brussels, a “water celebration” show in Louvain-la-Neuve, a pedestrian rally "Science in the city” in Liège will give the opportunity to the public to see ,among others, men feeding sharks, and for the very first time in Belgium, an astonishing full-dome shows presenting the Planet earth will be shown at the Planetarium (in the 23m-dome of the Planetarium),. The main message that the organisers intend to communicate is that researchers are people like you and me, and that we need researchers in our daily life, but also we need them to save the planet. After that evening, researchers will be considerated much closer from the audience, having as consequence that research and science can be envisageable for a future career

Keywords: researchers night public awareness science promotion youth
Closing the Gaps between the Researchers and the Large Public (MULTICULTI SCIENCE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Portugal
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-06-01
End date: 2007-12-31
Duration (months): 7.0
Total project cost (EUR): 77427.0
EU funding (EUR): 70000.0
Participants: 3
Project status: CLOSED

In line with the objectives of the Researchers’ Nights of enhancing large public recognition of researchers as well as their role in society and within citizens’ daily life, the MultiCulti Science project aims at creating a ‘multidisciplinary platform’ to give the general public, especially young people, the opportunity to meet researchers within a fun and unique context. The main strategic objectives of the project are to: - establish a ‘face-to-face platform’ to communicate scientific issues by bringing together at least 35 researchers from several areas and 2000 people allowing them to interact directly; - foster close, informal and creative dialogue between researchers and the public at large, by organising 3 Cafes Scientifiques; - give researchers the opportunity to show the two sides of their lives, through photo exhibitions showing their professional activities and personal interests; - give researchers and the general public the chance to ‘communicate outside the usual labs, through the organisation of multiple activities such as cocktail demonstrations or karaoke sessions; - foster the embarkation of young people on scientific careers by allowing them to ‘touch’ science through multiple hands-on experiments and demos; - give participants the opportunity to get to know more deeply the scientific panorama in Portugal and Europe through several informal, thematic workshops. The consortium of this initiative was built taking into account the experience and ability of each partner to accomplish the objectives above. The consortium is made of one Innovation Agency with large experience in cooperating with and involving SME and universities in RTD activities, one renowned Congress Centre with large experience in organizing large scale events addressed to a large number of people, and Visionarium, an interactive science museum expert in transferring and disseminating scientific knowledge to the general public, through the performance of leisure actions.

Keywords: science and society,multidisciplinary platform,interaction,relaxed and fun environment,science awareness,researchers' life and recognition.