Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Lifshitz holography: hydrodynamics and the large-D limit (HoloLif)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-10-01
End date: 2021-09-30
Duration (months): 24.0
Total project cost (EUR): 184590.72
EU funding (EUR): 184590.72
Participants: 1
Project status: CLOSED

Holography is the powerful statement that two seemingly distinct theories, a theory of gravity and a field theory, describe the same physics. In this proposal I focus on Lifshitz holography, a not very well understood version of the duality, that relates non-relativistic strongly-coupled field theories and gravity realized on Lifshitz spacetimes. The aim of the project is to further develop Lifshitz holography by taking advantage of recent progress in non-relativistic hydrodynamics and the development of the large-D tool. The research objectives(ROs), each forming a separate work package, are: - Flesh out the connections between gravity and fluid dynamics for non-relativistic theories, by developing the membrane paradigm for Lifshitz black holes. This will not only be a milestone in our understanding of Lifshitz holography itself and prepare the ground for a fully-fledged non-relativistic fluid/gravity correspondence, but it will also elucidate the infrared properties of these theories, identify universal behaviours in transport coefficients and other observables and explore the generality of recently-proposed connections between hydrodynamics, non-hydrodynamic modes and chaos. - Extend the large-D tool to Lifshitz spacetimes and then use it to study holographically thermal transport in Lifshitz theories. The large-D is a technical development in general relativity realised on Anti-deSitter and flat spacetimes that leads to major simplifications of gravitational dynamics and thus eases the complexity of calculations. This objective will impact both holographic studies and gravity considerations in Lifshitz spacetimes. To achieve these ROs, I will mainly study various aspects of quasinormal modes. These modes not only contain information about black hole dynamics in the sense of characterising the dissipation of the perturbed horizon, but they are also associated with poles of the corresponding real-time Green's functions in a holographically dual theory.

Keywords: holography,non relativistic field theories,gravity,black holes,hydrodynamics,quasi normal modes,large d
Novel Quantum Emitters monolithically grown on Si, Ge and III-V substrates (4PHOTON)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany,Germany,Germany,Italy,Italy,Switzerland,Sweden,Russian Federation,France,France,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom,Japan
Call: Innovative Training Networks (H2020-MSCA-ITN-2016, 2016)
Start date: 2017-01-01
End date: 2021-06-30
Duration (months): 54.0
Total project cost (EUR): 3900365.28
EU funding (EUR): 3900365.2800000003
Participants: 17
Project status: CLOSED

We propose to forge a partnership between the leading European groups working on the next generation of solid state quantum emitters based on novel growth methods such as Droplet Epitaxy. Future, practical Nano-photonics and Quantum Circuits applications demand semiconductor quantum dots that can be grown on substrates with different lattice parameters (Si, Ge, GaAs), different substrate orientations (such as (001) and (111)) and tuneable optical, electrical and spin properties. All these requirements are met by high quality quantum dots grown with Droplet based Epitaxy techniques, circumventing the limitations of currently available systems based on strain-driven dot self-assembly. This vast novel research area at the crossroads of photonics, material science, quantum physics and nano-scale device fabrication will allow delivering top level multidisciplinary training to 15 early stage researcher (ESRs). The successful training of the ESRs by leading academic and 3 full industrial partners will be crucial for achieving the headline goals of this first ever consortium on droplet dot devices: (1) Entangled light emitting diodes with droplet dots grown on (111) substrates (2) Electrically triggered, droplet dot based single photon sources on Si/Ge substrates (3) Strain tuning in droplet dots without wetting layer: photon polarization and single spin control (4) Droplet Dot based single photon sources for non- classical light storage devices based on hybrid quantum systems (dots & laser-cooled atoms). The training and research progress will be discussed and monitored during the 4 project meetings, 3 summer schools and the final international conference on Droplet Dot Devices, all of which are open to the whole scientific community. We expect this network, based on the solid collaboration between growth groups, microscopists, quantum optics experimentalists and theorists to explore the full potential of this emerging technology.

Keywords: droplet epitaxy,semiconductor quantum dots,single photon sources,hybrid quantum systems,quantum optics,quantum optical circuits
Osteoarthritis patient cohorts in the dish - personalised cellular drug development tools for osteoarthritis precision medicine (O-POINTED)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Osteoarthritis is the fastest growing cause of disability worldwide. Still, there is currently no drug available that targets the underlying pathophysiology of osteoarthritis. Clinical trials testing disease-modifying drug candidates consistently fail. This is because osteoarthritis is a complex disease and currently used drug development tools completely disregard patient variability. Consequently, such non-personalised drugs fail to reach high enough response rates in highly variable osteoarthritis patient populations. O-POINTED is the first tool to enable pharma and biotech companies to personalise the osteoarthritis drug development process. O-POINTED is a cellular test system based on personalised and expandable cell lines generated from a cohort of more than 50 osteoarthritis patients. It represents osteoarthritis patient variability including all the main disease phenotypes (bone-, cartilage-, synovium-driven). Compared to conventional test systems, it is easier to use and more relevant, with the unique benefit of representing osteoarthritis patient variability. The combined O-POINTED business model includes a double one-off revenue (product plus consumables) and recurring revenue (milestone-based payments). We estimate that O-POINTED will create €2.9 million revenue and 15 new jobs, 3 years after commercial launch. We have a key customer already testing a minimal viable product of O-POINTED and seek Phase 1 support to evaluate the feasibility of scaling up to a European and Global dimension.

Keywords: precision medicine,osteoarthritis,patient stratification,drug development,in vitro
Aesthetic and Anthropological Representations as Evidence of Racism: from Italian Unification (1861) to the Fall of Fascism (1943) (ARER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-11-01
End date: 2022-10-31
Duration (months): 24.0
Total project cost (EUR): 175673.28
EU funding (EUR): 175673.28
Participants: 1
Project status: CLOSED

This research project entitled Aesthetic and Anthropological Representations as Evidence of Racism: from Italian Unification (1861) to the Fall of Fascism (1943) (ARER) aims to study the role of visual and material culture in the formation of an African racial identity during Italy’s national unification and its colonial conquests up to the fall of fascism. Italian colonialism, later than that of its French and English neighbours, coincided with the constitution of the nation-state, and it was imperative that its first campaigns, exclusively turned towards Africa, reinforce patriotic sentiment and inscribe Italy among the colonial powers. The figure of the Italian was thus invented progressively by way of contrast to African populations, and through the exaltation of its Roman and Etruscan origins, in order to legitimate its vocation to conquer and ‘civilize’ the world. Situated at the crossroads of art, history and anthropology, the theoretical results of my study have for an ambition to help question the contemporary resurgence of racism and xenophobia in a Europe affected by a migration crisis and the rise of populism.

Keywords: race,visual culture,material culture,anthropology,colonialism,fascism
Cubbit. The first distributed data-center. (Community Cloud)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-06-01
End date: 2018-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Cubbit srls is a high-tech startup developing new technologies for cloud services industry. Founded in July 2016, the company is based in Bologna (Italy) and backed by VC fund Barcamper Ventures. Companies that use cloud services look for excellent performances, competitive prices and the highest data security. They are now forced to choose between effectiveness and affordability. This problem arises because the current standard of centralised cloud (i.e. one web farm serving millions of users) has huge operating costs and recurring failure points concerning data security. Cubbit srls has invested €151k to develop a technology able to disrupt the global cloud industry by eliminating the root cause of its problems: centralised web farms. Cubbit replaces them with a distributed data-center based on a p2p network made of domestic servers that is cost-saving, scalable and secure by design. It is also environmentally sustainable: Cubbit uses around 10 times less energy than centralised cloud does. This is why Cubbit srls was selected by EIT Climate KIC in 2017. Via a simple and cheap domestic server, Cubbit’s software recycles users’ internet resources that are currently unexploited. It re-sells them to business customers (SMEs) in the form of cloud services that are at the same time secure, efficient and inexpensive. The generated value is shared back with the users though the Open Revenue Program. Cubbit leverages the power of crowd-sourcing in opposition to the current ownership-based cloud to create a Community Cloud. As in a mutual company, the users that join Cubbit both contribute to and benefit from our co-op network. The first cloud service provided by our distributed data-center is Cubbit for Individuals, currently at TRL6. We are applying to conduct the Feasibility Study on two main long-term objectives: 1| delivering over time the main web services that are now prerogative of centralised data-centers; 2| expanding from Europe to the global market
Attosecond Electron Dynamics in MOlecular Systems (AEDMOS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-05-01
End date: 2020-04-30
Duration (months): 60.0
Total project cost (EUR): 1999375.0
EU funding (EUR): 1999375.0
Participants: 1
Project status: CLOSED

Advanced insight into ever smaller structures of matter and their ever faster dynamics hold promise for pushing the frontiers of many fields in science and technology. Time-domain investigations of ultrafast microscopic processes are most successfully carried out by pump/probe experiments. Intense waveform-controlled few-cycle near-infrared laser pulses combined with isolated sub-femtosecond XUV (extreme UV) pulses have made possible direct access to electron motion on the atomic scale. These tools along with the techniques of laser-field-controlled XUV photoemission (“attosecond streaking”) and ultrafast UV-pump/XUV-probe spectroscopy have permitted real-time observation of electronic motion in experiments performed on atoms in the gas phase and of electronic transport processes in solids. The purpose of this project is to to get insight into intra- and inter-molecular electron dynamics by extending attosecond spectroscopy to these processes. AEDMOS will allow control and real-time observation of a wide range of hyperfast fundamental processes directly on their natural, i.e. attosecond (1 as = EXP-18 s) time scale in molecules and molecular structures. In previous work we have successfully developed attosecond tools and techniques. By combining them with our experience in UHV technology and target preparation in a new beamline to be created in the framework of this project, we aim at investigating charge migration and transport in supramolecular assemblies, ultrafast electron dynamics in photocatalysis and dynamics of electron correlation in high-TC superconductors. These dynamics – of electronic excitation, exciton formation, relaxation, electron correlation and wave packet motion – are of broad scientific interest reaching from biomedicine to chemistry and physics and are pertinent to the development of many modern technologies including molecular electronics, optoelectronics, photovoltaics, light-to-chemical energy conversion and lossless energy transfer.

Keywords: attosecond spectroscopy,ultrafast electron dynamics in molecular systems,photocatalysis,dynamics of electron correlation in high t c superconductors
Token Communities in the Ancient Mediterranean (Token Communities)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-06-01
End date: 2021-08-31
Duration (months): 63.0
Total project cost (EUR): 1033723.0
EU funding (EUR): 1033723.0
Participants: 1
Project status: CLOSED

This project will provide the first comprehensive analysis of the role played by tokens in the ancient Mediterranean. Tokens are frequently found on archaeological sites and within museum collections, but are little studied and poorly understood. These objects played a central role in cultural, religious, political and economic life in antiquity; closer study of these objects is thus imperative in gaining a fuller picture of the ancient world and its cultural legacy. An interdisciplinary team will examine tokens and their contexts within the ancient world, focusing on the periods when they are in highest use: the Hellenistic period (postdoctoral researcher) and the Roman world (PI and 2 PhD students). The project will combine an analysis of museum material with the known archaeological contexts of these objects. It will be the first project to approach these items in a cross regional and fully contextualised manner. This approach will enable researchers to better define what tokens were in antiquity, and what roles they played. Moreover, through a careful consideration of type, context, and distribution, the project will also explore how these objects actively contributed to the generation of different types of community. The envisaged outcomes will provide a basis for the study of tokens more broadly, generating insights that will inform the display, scholarly use and understanding of these objects within museums and other spaces. The exploration of how tokens and token-communities within antiquity existed alongside official currencies and groups will also provide an important historical parallel for the contemporary development of alternative currencies, their associated values, and communities.

Keywords: numismatics
Intelligent Wireless Sensor Networks for Asset Integrity Monitoring (I-WSN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Netherlands
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2015-05-01
End date: 2015-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The objective of I-WSN is to develop a low-cost and large-scale solution for automated Condition Monitoring and Predictive Maintenance that will have a disruptive impact on the offshore Operations and Maintenance market. The solution is based on intelligent Wireless Sensor Networks that monitor the long-term trend in the status of the equipment and can predict damages at an early stage. The focus market segments for direct application of I-WSN are offshore Oil & Gas and Wind Energy. We have already received significant interest from potential business partners in this market segment, ranging from global suppliers (Honeywell), to maintenance providers and even Oil & Gas giants (BP). Unlike existing condition monitoring systems, which are very complex and expensive, I-WSN focuses on a low-cost solution (target price €500/unit) that can be installed on a large number of devices, machinery, equipment and structures. This brings significant benefits to the end-users, such as: - Up to 75% cost reduction of maintenance operations: extension of maintenance intervals, reduction of workload of maintenance personnel. - Up to 90% cost reduction of installation of monitoring equipment: wireless sensors compared to traditional wired systems. - Real-time feedback and continuous monitoring within minutes, as opposed to weeks or months for time-based inspection. I-WSN will build upon the success story of the FP7 project WiBRATE, showcased in two FUTURIS episodes on EURONEWS in 2014. The WiBRATE wireless sensor platform will be used as the basis, since it has been already validated in industrial settings (at FIAT, Honeywell, LMS-SIEMENS). I-WSN thus starts from TRL6 and higher, and has the potential for Open Disruptive Innovation in an offshore Operations & Maintenance market estimated at €2-3 billion. Phase 1 of the SME instrument has the objective to check the economic, technical and operational feasibility, and to bring us closer to marketing a successful product.

Keywords: condition monitoring,predictive maintenance,wireless sensor networks,offshore industry,oil and gas,wind energy,monitoring and control
Complement: to clear or not to clear (C-CLEAR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Netherlands
Call: ERC Advanced Grant (ERC-2017-ADG, 2017)
Start date: 2018-07-01
End date: 2023-12-31
Duration (months): 66.0
Total project cost (EUR): 2332500.0
EU funding (EUR): 2332500.0
Participants: 1
Project status: SIGNED

Mammalian complement recognizes a variety of cell-surface danger and damage signals to clear invading microbes and injured host cells, while protecting healthy host cells. Improper complement responses contribute to diverse pathologies, ranging from bacterial infections up to paralyzing Guillain-Barré syndrome and schizophrenia. What determines the balance between complement attack reactions and host-cell defense measures and, thus, what drives cell fate is unclear. My lab has a long-standing track record in elucidating molecular mechanisms underlying key complement reactions. We have revealed, for example, how the interplay between assembly and proteolysis of these large multi-domain protein complexes achieves elementary regulatory functions, such as localization, amplification and inhibition, in the central (so-called alternative) pathway of complement. Results from my lab underpin research programs for the development of novel therapeutic approaches in academia and industry. Here the goal is to understand how the molecular mechanisms of complement attack and defense on cell membranes determine clearance of a cell. Enabled by new mechanistic insights and preliminary data we can now address both long-standing and novel questions. In particular, we will address the role of membrane organization and dynamics in complement attack and defense. Facilitated by recent technological developments, we will combine crystallography, cryo-EM, cryo-ET and high-resolution microscopy to resolve complement complex formations and reactions on membranes. Thus, this project aims to provide an integrative understanding of the molecular complement mechanisms that determine cell fate. Results will likely be of immediate importance for novel therapeutic approaches for a range of complement-related diseases. Furthermore, it will provide clarity into the general, and possibly fundamental, role of complement in tissue maintenance in mammals.

Keywords: complement,membrane dynamics,membrane proteins,structural biology,immunology