Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
software PLATform fOr iNteroperable multiphysics digital mock-up (Platon)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: France
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2015-02-01
End date: 2015-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Simulation tools for virtual dynamic mock-ups are more and more adopted by product engineers because they produce essential engineering insights, avoiding significant time and cost investments. Nevertheless, the different modules of the PLM flow do not communicate each other and existing studios suffer from a non-integrated approach. Going cheaper and faster will require new technical offers and business models. Platon will solve these issues by bringing a disruptive approach at the international level. It will provide an interoperable single environment to applications which will share the same digital mock-up, allowing easier product analysis and optimization. Customers will be able to target 0 costly prototype and to increase engineers’ productivity. Indeed, Platon will enable users to 1) automate many repetitive design and modelling tasks, 2) evaluate the impact of design changes, 3) deploy best practices to non-experts and 4) partner with design & engineering colleagues more effectively. Phase 1 will investigate identified bottlenecks and allow a deeper market analysis. The results will be delivered in updated business plan, leading the solution to the market with clear, measurable, realistic and achievable objectives. Optis’ strategy is based on a win-win approach with stronger ROI for the entire ecosystem. Optis is structured with international subsidiaries and has delivered more than 7000 licenses worldwide. PLATON already owns its dedicated distribution network and a wide base of clients. Platon will enable Optis to move from a technology provider position to a solution provider status while other editors proposing complementary approaches will become natural partners through a specific platform agreement.

Keywords: productivity,business model,automotive,distribution,interoperability,application,digital mock up,natural interfaces,multi physics platform,simulation,extensibility,interfaces
A New Zn-Air Battery Prototype to Overcome Cathode Degradation Through Catalyst Confinement (ZABCAT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Spain,Spain
Call: Call for proposals for ERC Proof of Concept Grant (ERC-2020-PoC, 2020)
Start date: 2021-10-01
End date: 2023-06-30
Duration (months): 21.0
Total project cost (EUR): 150000.0
EU funding (EUR): 85500.0
Participants: 2
Project status: SIGNED

Zinc-air rechargeable batteries are a promising alternative for sustainable energy storage, thanks to their high energy density and the use of abundant materials with low environmental impact, as well as their safe operation. However, they still have some technological limitations that prevent their current capacity from being completely satisfactory, especially because of the degradation that occurs at the cathode and corrosion of the anode, which ultimately limit both the reversibility and a long battery life. The proposed methodology allows to protect the (electro)catalytic centers. In this way, it is intended to extend its useful life, improving both its behavior in real conditions, and solving the existing problems in the electrodes. Thus, based on this technology, new electrodes will be manufactured that will later be tested in pre-industrial battery prototypes

Keywords: bifunctional air catalyst,secondary zinc air battery,bifunctional air electrode,aqueous alkaline electrolyte,optimized preindustrial cell prototype
Mechanosensation and the circadian clock: a reciprocal analysis (Clock Mechanics)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-09-01
End date: 2022-12-31
Duration (months): 88.0
Total project cost (EUR): 1899549.0
EU funding (EUR): 1899549.0
Participants: 2
Project status: SIGNED

All forms of life adjust themselves to the daily rhythms of their environments using endogenous oscillators collectively referred to as circadian clocks. Peripheral and central body clocks exist, which both require extrinsic information (e.g. light or temperature changes) to keep in sync with the geophysical cycle (entrainment). In addition, intrinsic cues (e.g. activity levels) have been linked to clock entrainment. Recently, we could show that activation of proprioceptors is sufficient to entrain the central clock of the fruit fly Drosophila melanogaster. Proprioceptors are mechanosensors that monitor the positions, and relative movements, of an animal’s own body parts. The existence of proprioceptive entrainment pathways has significant implications; it implies that an animal’s ‘clock time’ is computed by integrating, and weighting, various external and internal conditions, suggesting the existence of external and internal time. Using Drosophila, I will investigate the relationship between mechanosensory and circadian systems in a dual, and bidirectional, approach. The project’s first aim is to dissect the neurobiological bases of proprioceptive clock entrainment (i) identifying the specific stimulus requirements for effective entrainment, (ii) determining its mechanosensory pathways and, in a combined computational and experimental strategy, (iii) quantifying the precise contributions of an animal’s activity to its sense of time. The project’s second aim, in turn, is to unravel the roles of the clock, and clock genes, for the function of mechanosensory systems. Previous studies have linked the clock to noise vulnerability in mammalian ears, and clock genes to regeneration in avian ears. Our own preliminary data reveal severe mechanosensory defects in flies mutant for core clock genes. I will use the Drosophila ear as a unifying model to analyse the specific roles of the clock, and clock genes, for the function of mechanotransducer systems.

Keywords: circadian entrainment,mechanosensation,auditory transduction
An innovative, thin and quick-to-install prefabricated Prefabricated ‘click-in’ underfloor heating system capable to be installed directly on the existing floor and connectable to the radiator system. (HEATILE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy,Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

Across the EU, there is a need to increase the energy efficiency of heating and cooling systems as 50% of all energy consumption across the EU is spent on heating and cooling. Underfloor heating systems can significantly contribute to this. However, currently, underfloor heating system have the following challenges: • Require invasive demolition works that can take up to several months • Lack leakage detection system • Results in increased floor thickness • Requires architectural changes • Higher energy bills due to high thermal inertia Heatile S.r.l has developed HEATILE, an innovative easy-to-install prefabricated underfloor heating system resolving the problem of invasive demolition works, high retrofitting costs, floor thickness and liveable heights and leakage detection. Our solution is simple to install in comparison to competitors’ products and does not require extensive labour. Our target users are the system installer (Architect, Designers and Contractors) and the end-Users, (Building Owners and Occupants). Our solution, provides the following: • Boost in productivity for installers: The easy to install modular solution cuts installation time by more than 90% thereby allowing more jobs to be done. • Reduction in installation costs for building owners: Installation costs are reduced by 15-25% as there is no need for demolition works during retrofitting. • Reduction in energy bills: HEATILE is a low thermal inertia system, heating a home in only an hour instead of the 12hrs. • Reduction in Carbon emissions: Our solution decreases household energy usage hence reducing CO2 emission. By the 5th year of commercialisation, we expect to sell about 160,000sqm generating a cumulative revenue of €26.60-m and cumulative EBIT of €2.545-m creating 22 jobs.

Keywords: underfloor heating,heating solutions,heating tiles,home renovation,energy efficiency
A precise irrigation monitoring system to provide an accurate measurement of water status in crops (StemSense)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 2102350.0
EU funding (EUR): 1471645.0
Participants: 1
Project status: CLOSED

There is an increasing global pressure on water resources and ensuring there is a sufficient supply in the face of climate change. This is of particular prevalence within the agriculture industry where irrigation is becoming increasingly important. Farmers typically overwater plants by 20% due to insufficient knowledge of plant water status resulting in significant wastewater and lowering plant yields. Saturas have developed StemSense, a unique sensor device that measures Stem Water Potential (SWP). SWP is scientifically proven to provide the most accurate data on plant water status. Saturas’ system then interprets this data, incorporating external factors such as meteorological data and provides recommended levels of irrigation to farmers. Farmers using the StemSense sensor experience up to 20% higher income, significant water savings and reduced costs. The overall objectives of the Phase 2 project are to design and engineer a miniaturised sensor that can be deployed in a wide variety of plants; to optimise the communication system and user interface; to scale-up production of StemSense with a contract manufacturer; and to demonstrate and validate the technology in in-field trials with farmers across Europe. The overall objective is to reach full commercialisation of StemSense as a reliable innovation validated by the relevant end-users, farmers.

Keywords: precision irrigation,crop water status,stem water potential,sustainable water use
Novel Photoprotective Cosmetics: From Fundamental Science to Product (SUNNRL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-08-01
End date: 2022-10-01
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: CLOSED

Drawing on the expertise from the applicants’ publications, wider academic research and recent contact with Lipotec, a global leader in Skin and Sun Care, this MSCA-IF-EF-SE application proposes to develop a novel sunscreen product which will deliver effective, safe and inexpensive broad-spectrum photoprotection. This project is aimed particularly at providing the global sunscreen industry with an alternative ultraviolet-A (UVA) filter: the UVA filter currently leading the market, avobenzone, quickly degrades upon absorption of UV radiation thus posing a significant risk to human health. The few currently available alternatives to avobenzone are too costly, resulting in unaffordable photoprotective products to consumers, which may have implications in skin cancer incidence. To develop this innovative, high-demand UVA-focused sunscreen product, the applicant will combine the sunscreen molecules she studied during her doctoral degree with the state-of-the-art cosmetic delivery system technology developed by Lipotec. The development of this product at Lipotec (Barcelona) will further the European scientific and technical leadership, as well as boosting the European Sun Care market and addressing the Horizon 2020 societal challenges regarding health and wellbeing.

Keywords: sunscreens,photoprotection,microencapsulations,microemulsions,materials science,formulations,photophysics
Zinc Oxide For TeraHertz Cascade Devices (Zoterac)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Austria,Spain,Switzerland,France,France,France
Call: FET-Open research projects (H2020-FETOPEN-2014-2015-RIA, 2014)
Start date: 2015-09-01
End date: 2020-02-29
Duration (months): 54.0
Total project cost (EUR): 3795877.44
EU funding (EUR): 3795876.94
Participants: 7
Project status: CLOSED

The terahertz (THz) spectral region, located between the infrared and the microwave regions, is known as “the THz gap” because of the lack of compact semiconductor devices. This spectral domain is currently intensively explored in view of its potential for medical diagnostics, security screening, trace molecule sensing, astronomical detection, space-borne imaging, non-invasive quality control or wireless communications. A prerequisite for public-domain applications to emerge in the strategic THz frequency range is the availability of compact size semiconductor sources operating at room temperature, which is out of range of the current technology based on GaAs quantum cascade lasers. ZOTERAC proposes a disruptive approach based on ZnO-based nano-engineered semiconductors in order to realize THz emitters operating at room-temperature with milliWatt output power capability as well as THz quantum detectors with unprecedented large operating temperatures. These devices are based on the quantum cascade concept and take benefit of the large optical phonon energy of ZnO (twice that of GaAs) for achieving high temperature operation. Establishing a new state-of-the-art for the design, growth and processing of ZnO/ZnMgO heterostructures, and developing an advanced know-how on oxide-based devices are major challenges of the project. The consortium regroups world–class academic experts on ZnO technologies, quantum cascade lasers and detectors as well as THz optoelectronics. The strategies have been chosen based on a careful assessment of the risk attached to all tasks and achievement of targeted objectives at each stage of the project. This project which implies a strong expertize in basic physics, chemistry and engineering, is expected to generate high impacts in terms of scientific and technological achievements.

Keywords: quantum cascade devices,wide band gap semiconductors,zinc oxide,intersubband transitions,thz laser
SCENT: Hybrid Gels for Rapid Microbial Detection (SCENT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Portugal
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-12-01
End date: 2022-05-31
Duration (months): 78.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: CLOSED

Antimicrobial resistant bacteria are a global threat spreading at an alarming pace. They cause over 25,000 annual deaths in the EU, and represent an economic burden exceeding €1.5 billion a year. Current methods for microbial detection in clinical settings take about 24-36 h, but for slow-growing bacteria, as those causing tuberculosis, it can take more than a week. Early-detection and confinement of the infected individuals are the only ways to provide adequate therapy and control infection spread. Thus, tools for rapid identification of bacterial infections are greatly needed. The analysis of microbial volatile metabolites is an area of increasing interest in diagnostics. Recent works demonstrate that fast microbial identification is possible with chemical nose sensors. These sensors usually present limited stability and selectivity, and require aggressive conditions during processing and operation. Bioinspired nose sensors employing biological olfactory receptors are an alternative. Unfortunately, their complexity and low stability are a limitation. My group recently discovered a new class of stimulus-responsive gels which tackle these key challenges. Our gels are customisable and have a low environmental footprint associated. I intend to further explore their potential to advance the field of odour detection, while providing new tools for the scientific community. I will focus specifically in fast microbial detection. To accomplish this, I propose to 1) build libraries of hybrid gels with semi-selective and selective properties, 2) generate odorant specific peptides mimicking olfactory receptors, 3) fully characterise the gels, 4) assemble artificial noses for analysis of microbial volatiles, 5) create databases with organism-specific signal signatures, 6) identify pathogenic bacteria, including those with acquired antimicrobial-resistances. This project is a timely approach which will place Europe in the forefront of infectious disease control.
Flight Qualification of Deployable Radiator using Two Phase Technology (PEGASUS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling European competitiveness, non-dependence and innovation of the European space sector
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Spain,Spain,France,Portugal
Call: Technologies for European non-dependence and competitiveness (H2020-COMPET-2014, 2014)
Start date: 2015-01-01
End date: 2018-09-30
Duration (months): 45.0
Total project cost (EUR): 3534173.5
EU funding (EUR): 3534173.5
Participants: 6
Project status: CLOSED

The main objective of this project is to develop a Deployable Thermal Radiator (DPR) based on Loop Heat Pipes Qualification Model. This includes the design, manufacturing and flight qualification testing to achieve a Technological Readiness Level (TRL) 8. The increasing demand of power rejection in current and future satellites requires the development of deployable radiator panels which can be stowed for launch and then deployed once the satellite is on its orbit. The development of such device implies several technical challenges: to transport efficiently the heat from the heat sources to the radiator, to increase the radiator area for rejecting higher powers but keeping a lightweight solution, and to accommodate a mechanism compliant with the functional requirements and the platform interfaces. Moreover, the DPR will be developed to guarantee modularity and scalability to be used in applications other than telecom such as Low Earth Orbit (LEO) missions, and in several platforms including full electric. The proposed design provides a solution flexible enough to adapt this technology to different heat transport systems such as Loop Heat Pipes and Mechanical Pumped Loops. To reach this goal, two specifications at system level will be issued for telecommunications and LEO applications. Considering these requirements, a DPR based on Loop Heat Pipes will be developed including a deployment mechanism which can cope with the functional needs. Several models will be manufactured. Two small scale models (one for telecom applications and the other one adapted to LEO specification) to demonstrate the fulfilment of the thermal performance and the scalability and adaptability of the design, and one DPR Qualification Model (QM). A complete flight qualification will be performed on this QM including mechanical and thermal testing at component and DPR levels. Therefore, the proposed project allows increasing the TRL of DPR, providing to the users a product fully qualified.

Keywords: deployable radiator,loop heat pipe,flight qualification
Cellular BIOtechnology for prognosis and monitoring in renal TRANSplantation (TRANSBIO)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Spain
Call: Supporting innovative SMEs in the healthcare biotechnology sector (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2017-01-01
End date: 2019-06-30
Duration (months): 30.0
Total project cost (EUR): 3846640.86
EU funding (EUR): 3845140.0
Participants: 1
Project status: CLOSED

Kidney transplantation is the treatment of choice for patients with end-stage kidney disease (ESKD). However, although surgical techniques and postoperative care have greatly advanced, renal transplantation is not empty of challenges. The most important challenge is to achieve the long-term survival of the transplanted organ. Graft survival depends on the ability of the recipe of not rejecting the “foreign organ”. Rejection is a naturally occurring process triggered by a biological response of the immune system, which main function in the body is to defend it against infectious organisms and other invaders. As such, the immune system is prepared to reject a “foreign organ”, something that is nowadays prevented by prescribing immunosuppressive therapies to the patients for their whole life. However, the use of immunosuppressive therapies entails important problems. On one side, suppressing the immune system implies severe side effects like opportunistic infections, cancer and other severe malignancies. On the other side, even under immunosuppressive therapies, about 50% of transplanted kidneys are lost during the first 10 years and this is because of an immune response usually described as chronic rejection. Therefore, the major challenges in ESKD deal with avoiding the side effects associated with immunosuppressant drugs and avoiding chronic rejection. In the TRANSBIO project we aim at bringing to the healthcare market a technology for efficient clinical management of patients undergoing a kidney transplant based on a simple and non-invasive blood test. Considering that worldwide, the number of people receiving renal transplantation annually is estimated at about 80,000 people, growing by approximately 6% annually and representing a prevalence of about 700 patients per million population, or what is the same about 5 million people living with a transplanted kidney, the TRANSBIO business opportunity seems unquestionable.

Keywords: kidney transplantation