Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
It takes a village: an interdisciplinary community neuroscience approach to characterize multigenerational interactions (InterCom)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Belgium
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2025-06-01
End date: 2030-05-31
Duration (months): 60.0
Total project cost (EUR): 3000000.0
EU funding (EUR): 3000000.0
Participants: 2
Project status: SIGNED

While many of our daily interactions involve people of different ages, little is known about how the human brain supports naturalistic communication between generations. InterCom combines laboratory research with real-world experimentation, and intrapersonal analyses with interpersonal measures (e.g. ‘brain-to-brain synchrony’), to better understand multi-generational communication, both within and beyond family contexts. Do age-related differences in brain rhythms inhibit conversational flow? How do listeners process speech produced by children or older adults? Can intergenerational miscommunications be partly attributed to the fact that children and older adults are less likely to predict what others are about to say? How can we overcome implicit neurobehavioral culprits of misalignment? Curiously, while laboratory studies have shown that there are significant differences in how children, adults, and older adults process (non)verbal information, these and related questions remain largely unanswered. InterCom will test a novel ‘community neuroscience’ approach, one that flows from the real world, to the lab, and back. We will collect brain, body, and language data from socio-culturally diverse groups of children, adults, and older adults during real-world storytelling events that are co-designed with community partners. The data collected during these events will then inform and constrain subsequent laboratory studies and vice versa. As such, InterCom leverages the benefits while offsetting the downsides of both naturalistic observations and experimental control, and will innovate on and combine laboratory and real-world data collection, stimulus development, and data analysis in a truly reciprocal manner. Together, InterCom will tread previously uncharted territory in both intergenerational and real-world neuroscience research to generate insights and tools to investigate and improve communication between and across generations.

Keywords: community science,brain computer interface technology,art science interface
Clean and efficient microCHCP by micro turbine based hybrid systems (Fit4Micro)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Belgium,Germany,Netherlands,Italy,Denmark
Call: Cost-effective micro-CHP and hybrid heating systems (HORIZON-CL5-2021-D3-03, 2021)
Start date: 2022-10-01
End date: 2026-09-30
Duration (months): 48.0
Total project cost (EUR): 4993387.5
EU funding (EUR): 4993387.5
Participants: 9
Project status: SIGNED

Fit4Micro aims to develop a hybrid microCHP unit running on sustainable liquid biofuels. Application is foreseen at multi-family houses, and more specifically at remote and/or off-grid locations. The innovative system is based on a double shaft micro gas turbine (mGT) combined with a novel humidification unit. This unique combination leads to very high electrical efficiencies (>40%) as well as a very flexible heat:power ratio. Low emissions are achieved by the application of flameless combustion, and a high GHG emission reduction is obtained by using truly advanced, RED2 compliant biofuel. Use of a mGT as core-unit in Fit4Micro is ideal for domestic usage, as the system has very low noise output and is vibration free. Furthermore, rapid response times and fuel-flexible operation make this the ideal base for a highly efficient hybrid CHP system, resilient to changes in (local) fuel and power markets, empowering the consumers through digital solutions. Furthermore, the Fit4Micro unit will be integrated with a compression heat pump, an innovative adsorption and a solar PV system through the DC power system avoiding transmission losses. A smart control system will be developed to enable optimal performance at all times. Efficient fuel distribution and off-grid operation of Fit4Micro is enabled by using sustainable liquid biofuels. These fuels will be produced from biomass residues and organic waste streams, through fast pyrolysis followed by mild hydro-processing yielding a hydrotreated pyrolysis oil (HPO). In Fit4Micro the objective is to widen the feedstock basis and lower the fuel costs by i) using residues as the primary feedstock, and ii) by limiting hydrogen consumption by application of mild processing conditions. Besides technological development work, the Fit4Micro project includes specific activities on socio-economic and environmental sustainability, public perception, gender dimensions, market aspects, the regulatory framework & policies.

Keywords: micro gas turbine,hybrid heating system,adsorption chiller,biofuel,biomass residues,organic wastes
On the UsE of Internet of Senses for the CuLturaL HerItagE (ELLIE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Innovation actions
Countries involved: Greece,Italy,Sweden,Cyprus,United Kingdom,Luxembourg
Call: Leverage the digital transition for competitive European cultural and creative industries (HORIZON-CL2-2024-HERITAGE-01, 2024)
Start date: 2025-01-01
End date: 2027-12-31
Duration (months): 36.0
Total project cost (EUR): 3907522.17
EU funding (EUR): 3299423.06
Participants: 13
Project status: SIGNED

Creative industries encompass a diverse array of sectors, including arts, craftsmanship, media, design, advertising, software, and more. Current research trends often focus on addressing various challenges and opportunities within these industries. One prevalent area of study involves examining the impact of emerging technologies on creative processes, particularly in terms of technological advancements and innovation. Artificial Intelligence (AI), Generative AI, Internet of Senses and Digital Twins (DTs) are key technologies frequently explored in this context. By leveraging these technologies within a virtual immersive world, there is potential to create an innovative platform that opens up opportunities for novel services in the Cultural and Creative Industries (CCIs) domain. ELLIE aims to support CCIs in enhancing their portfolios by providing a universal platform that integrates multiple high-impact technologies like the above and immersive worlds. This platform seeks to facilitate the creation of new user experiences, simplify the development of creative products, and better understand user needs. ELLIE's overarching objective is to offer a comprehensive solution that aids in the delivery of advanced services and expedites the production of new products. This initiative empowers stakeholders to streamline the workflow of service and product creation. Through the combination of the above technologies, ELLIE supports innovative and automated processes, ultimately providing end users with high-quality experiences.

Keywords: digitization,personalized data provision,augmented reality,virtual reality,artificial intelligence,digital twins,internet of senses,immersive virtual worlds
OXO-001, a novel first in class oral, non- hormonal tablet, to enhance live birth in women undergoing assisted reproductive technology (OXO-ART)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Infertility affects approximately 76 million women globally each year, posing a significant challenge with profound impacts. Oxolife, a pioneering Spanish clinical-stage women's health company, addresses this critical issue with its innovative treatment, OXO-001. This first-in-class, non-hormonal oral tablet enhances embryo implantation and represents a breakthrough for women undergoing IVF/ICSI treatments. OXO-001 works by increasing the transcription and expression of key surface molecules on endometrial cells, thereby facilitating better embryo adhesion and invasion. Phase II clinical trial studies demonstrate a substantial improvement in ongoing pregnancy rates and live birth rates, particularly in women under 40. The market potential for OXO-001 is significant, targeting a global infertility treatment market projected to reach $45 billion by 2029. Our serviceable addressable market is estimated to be €3.7 billion by 2038, driven by changing trends in the average age of mothers. OXO-001 aims to transform the fertility treatment landscape with fast and deep uptake, offering a novel solution that significantly enhances the chances of successful pregnancies for women undergoing IVF/ICSI treatments. Oxolife seeks €2.5 million in grant funding and €15 million in equity from the EIC to support final development stages, including GMP manufacturing and pivotal Phase III clinical trials. This funding is crucial to de-risk the preparation and execution of the Phase III trial and to attract additional private investment necessary for bringing OXO-001 to market. In doing so, this innovation not only addresses a major unmet medical need but also has the potential to reduce healthcare costs, alleviate the psychological and financial burdens on affected couples, and support global efforts toward better reproductive health.

Keywords: women s health,female infertility,embryo implantation,ivf,icsi,art cycles,pregnancy,phase iii,live birth rates
Japan, Religious Education And Critical inTerculturalism. Approaches from the Study of Religions and Didactics. (JREACT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Japan,Germany
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-15
End date: 2028-09-14
Duration (months): 36.0
Total project cost (EUR): 384915.24
EU funding (EUR): 384915.24
Participants: 3
Project status: SIGNED

The JREACT Project wants to provide a non-confessional model for teaching about religions in schools, i.e. Religious Education (RE), that eschews ethnocentrism and promotes critically self-reflection, diversity and inclusiveness. It does so by engaging the case-study of RE in Japan from the point of view of the academic Study of Religion (SoR). In the last 20 years debates and developments on RE and Intercultural/Citizenship Education (ICE) have increasingly intersected, especially in Europe. However, the SoR has since long criticized the modern, Christian and ethnocentric biases inherent in the concept of “religion”, thus highlighting an intrinsic intercultural weaknesses in RE. Nonetheless, International/European research aimed at the creation of SoR-based RE didactics still lacks a thorough engagement with non-western contexts. This hinders the creation of a full-fledged intercultural and inclusive RE. JREACT want thus to improve European SoR-based RE through a comparative analysis with the Japanese case. The reasons to choose Japan are its peculiar religious situation (which often eludes Eurocentric views on religions), its long scientific tradition (for and non-European country) in the modern study of religion, and an ongoing debate on the role of RE in schools. It will contextually compare Japanese and European SoR-based RE theories and methods, looking for unnoticed biases, mutually reinforcing points, uncharted areas and contrasting points. From this it will elaborate innovative concepts and methods for RE and articulate them into guidelines. Its interdisciplinary approach combines SoR, Didactics, Anthropology of Education and ICE. JREACT will establish my position as an expert in intersecting fields: comparative RE; society & religion in contemporary Japan, theoretical issue in SoR, Didactics and ICE. At the societal level, it will innovate the debate and the practices concerning RE in European schools from the perspective of critical ICE.

Keywords: study of religions study of religions based non confessional religious education in europe japanese religious education subject didactics intercultural education critical postcolonial approaches
Precision medicine approach to rare vascular malformations to enhance understanding, diagnostics and therapy (PREVENT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative B iology : from Genes and Genomes to S ystems
Panel description: For all organis ms: Genetics, epigenetics, genomics  and other ‘omics studies , bioinformatics, systems biology , genetic diseases , gene editing, innovative methods and modelling,  ‘omics for personalised  medicine
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-04-01
End date: 2028-03-31
Duration (months): 60.0
Total project cost (EUR): 1498316.0
EU funding (EUR): 1498316.0
Participants: 1
Project status: SIGNED

Vascular malformations are clinically very heterogeneous ranging from small local ‘birthmarks’ to life-threatening entities affecting entire limbs, organs or larger parts of the human body. Often, these conditions require surgical and/or pharmacological intervention to prevent further disease progression and to increase patients’ quality of life. Therefore, an accurate diagnosis is crucial for appropriate treatment and management. However, our current knowledge on vascular malformations is very limited, making diagnosis and treatment very difficult due to: 1) An inadequate understanding of the underlying histological alterations causing the phenotype. 2) Very limited genetic diagnostic testing, which in most cases does not allow a confirmed molecular diagnosis. 3) Poor curative surgical and pharmacological treatment approaches. As the current pharmacological therapy regimen with drugs from oncology or transplantation medicine is more like a try & error than a precision medicine approach, there is a high risk of drug side effects and non-response to therapy and thus progression of the disease. I want to tackle these obstacles with a multidisciplinary approach to precision medicine for vascular malformations to prevent disease progression and improve patient outcomes. Therefore,my proposed workflow provides: 1) A novel histological classification based on deep phenotyping using diagnostic AI-assisted 3D-Histology, 2) Improved diagnostic testing through analysis of the coding and non-coding genome using state-of-the-art sequencing techniques and bioinformatics tools, and 3) Patient-tailored pharmacological treatments based on FDA-approved drug sub-library screenings tested on the patient-derived cells using state-of-the-art imaging techniques. This innovative approach to precision medicine has the great potential to transform clinical practice and provide for the very first time state-of-the-art diagnosis and treatment for patients with vascular malformations.

Keywords: precision medicine,vascular diseases,rare diseases,genetic testing,histology,imaging,pharmacological treatment of rare diseases
First feasible and scalable gesture recognition technology for interacting with augmented reality using widely available smartwatches (Doublepoint)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Finland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Doublepoint has developed novel gesture recognition technology for making highly intuitive interaction feasible for augmented reality (AR). The emergence of AR is the next revolutionary wave of computing, offering unprecedentedly immersive digital experiences for significant economic and social benefit. Yet there is a critical user interface challenge that today strongly inhibits AR potential, as existing intuitive interface methods do not fit into computational and hardware capacity of light and ergonomic AR headsets. Our deep learning technology resolves this issue by enabling natural microgesture based digital input detected from physical changes in the wrist with sensitive sensors in retail wristwear devices. Focusing on recognizing unique signals of natural gestures directly from wrist enables highly intuitive gesture input with unprecedented computational efficiency, robustness, and speed, while use of widely available sensors ensures its very affordable scalability.

Keywords: augmented reality,gesture recognition,microgesture input,raycasting
A DISRUPTIVE TOOL FOR VERIFICATION OF EDUCATIONAL DOCUMENTS (EdVeriTrust)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Bulgaria
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

In an increasingly competitive job market, especially in the highly qualified staff segment, many job seekers choose to stand out from the crowd by using fake diplomas or professional certificates. Between 70-90% of people lie on their resumes about their education and prior experiences, and the astonishing 29% either falsify diplomas or use diploma mills. Catching them is hard. This is a slow, expensive, and unreliable manual process. EdVeriTrust will help employers confirm the qualifications of job applicants quickly and securely at a fraction of the costs they currently bear. It will make sure that the documented advantages and qualifications of shortlisted job applicants are genuine, making the labor market just and transparent. EdVeriTrust will be the first real-time, reliable, standardized, and secure digital method for verification of educational credentials in the world. The process will be fast, and secure, and will not require the physical handling of sensitive documents. Our target is the European educational documents verification market. It is expected to reach 750 M euros in 2028 creating an opportunity for EdVeriTrust worth 112.5 M euro revenues in 2028.

Keywords: it,digital identity,credentials verification,digitization,software development,education,job market,degrees
Developing plug-and-play industry 4.0 solutions for SMEs (dataLobster)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2450000.0
EU funding (EUR): 2450000.0
Participants: 1
Project status: SIGNED

The dream of smart factories powered by AI and digital technologies (Industry 4.0) is often out of reach for small and medium-sized enterprises (SMEs). High upfront costs, complex deployment processes, and the need for additional personnel or technical expertise create significant hurdles. DataLobster overcomes these challenges with its innovative plug-and-play IoT+AI Lobster multi-sensors. The unique features of the solution that makes it suitable for SMEs include: • Zero upfront investments • 1-Day Installation • Secure cloud storage • AI-powered reporting • Infinite flexibility to add Lobsters as needs change or grow • Comprehensive monitoring as a single Lobster combines 8 sensors for a complete picture of the equipment's health and performance. With Datalobster’s innovation, SMEs will have a smooth and efficient way to embrace Industry 4.0, increasing efficiency, reducing costs, and minimizing their energy footprints. Favorable government regulations worldwide are driving the equipment monitoring market toward a projected value of $5.4B by 2032. DataLobster is perfectly positioned to capitalize on this massive opportunity and become a leader in the industry.

Keywords: iot devices,multi sensors,industry 4 0,equipment performance,equipment health
Mapping the dynamics of consciousness: A unified account of variability in responsiveness across the spectrum of consciousness in health and disease (DynamiConsciousness)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Israel
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-07-01
End date: 2031-06-30
Duration (months): 60.0
Total project cost (EUR): 1721250.0
EU funding (EUR): 1721250.0
Participants: 1
Project status: SIGNED

The unconscious brain’s ability to detect and identify stimuli is essential for our and our loved ones’ survival. For example, recognizing the smell of a fire or our baby's cry. What determines if and how the unconscious brain processes and reacts to information from the environment? As consciousness level diminishes (e.g., during sleep or following brain injury), slow wave activity (SWA) increases, weakening the input-output relationship and increasing response variability. Surprisingly, no study to date has adopted a variability-based approach to responsiveness, seeking common principles that persist across the spectrum of consciousness in both health and disease. DynamiConsciousness introduces a novel principled framework positing that SWA regionality (i.e., topography across regions) governs responsiveness variability across natural and pathological unconsciousness. I hypothesize that (1) SWA regionality nonlinearly modulates stimulus-induced intra-individual variability (IIV), exhibiting an inverted U-shape relationship, (2) Brain network dynamics is shaped by SWA and govern IIV in a modality-dependent manner, and (3) that IIV can predict consciousness recovery dynamics at the individual level. These hypotheses will be tested through multimodal experiments tailored for altered states of consciousness and by quantifying variability across modalities and time scales in healthy participants (sleep studies) and disorders of consciousness patients (longitudinal study). This interdisciplinary project, combining electrophysiology, neuroimaging, and physiology, offers a new unified framework for understanding responsiveness across the consciousness spectrum by linking within-person variability and SWA regionality. This approach will provide a unique lens for understanding brain functionality and promote a paradigm shift in the way we conceptualize and study consciousness.

Keywords: sleep disorders of consciousness slow waves olfaction variability eeg fmri respiration