Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
From instructions to actions: characterizing the spatiotemporal neural signatures of instructions following. (InstrAct)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 166320.0
EU funding (EUR): 166320.0
Participants: 1
Project status: CLOSED

From air traffic control to large surgery teams, some of the most advanced human collaborative achievements largely rely on our ability to successfully give and follow instructions. Given the combination of novelty, speed, complexity and efficiency, significant effort has been devoted to characterize the mechanisms underlying this ability. However, how the human brain rapidly (i.e. in a matter of seconds) transforms the content of instructions into actions is still poorly understood. This project aims at providing a fundamental description of this transformation by combining recently developed behavioral paradigms and cutting edge methodological and analytical tools. This combination is expected to result in a significant step forward in the understanding of instructions following, compared to the state-of-the-art. This project is especially timely given its relevance to ongoing debates in cognitive neuroscience regarding the structure of cognitive control and working memory systems. InstrAct will also be highly relevant to other disciplines such as robotics and artificial intelligence, which could benefit from the outcomes of this project to implement human-like, complex collaborative artificial systems, a crucial milestone in these fields. The success of this proposal relies on the combination of my expertise on multivariate analysis of neuroimaging data with the strong theoretical guidance offered by Dr. Brass’ team at the Faculty of Psychology and Educational Sciences, Ghent University, a critical hub for cognitive control and instructions following in particular. The expected outcome of this project will, first, enhance the role of Ghent University and Europe as a hub for excellent research on instruction following. Second, it will be a boost in crucial aspects of my career, specifically, in the acquisition of new methodological and theoretical competences, allowing me to achieve my long-term goal of becoming an independent researcher.

Keywords: cognitive control,instruction following,working memory,neuroimaging,functional magnetic resonance imaging,mvpa
Hybrid Materials for Artificial Photosynthesis (HyMAP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Spain
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-07-01
End date: 2022-12-31
Duration (months): 90.0
Total project cost (EUR): 2506738.0
EU funding (EUR): 2506738.0
Participants: 1
Project status: CLOSED

HyMAP aims to develop a new generation of multifunctional hybrid photocatalysts and solar photoreactor which would allow the exploitation of at least the 1 % of the sunlight energy for the CO2 photoreduction using water as electron donor. This will imply a CO2 conversion in the range of 12 to 35 Ton/y•ha, depending on product distribution, which represents at least a 20-fold improvement over the state of the art. To achieve this goal, I propose an interdisciplinary research program through which several breakthroughs at different scales will be achieved: Development of efficient multifunctional organic/inorganic semiconductors and metal-organic frameworks photocatalysts with separated reduction/oxidation active sites. The fact of having independent multiple redox sites combined in a single material would maximize charge separation and transport processes, as well as sunlight harvesting. Characterization and modelling of the structural and opto-electronic properties of the proposed materials. Evaluation of the materials in artificial photosynthesis devices. At this stage, a solar photoreactor that would allow good transmission, uniform light distribution and maximize the energy harvesting in the overall spectra will be developed. HYMAP will provide me with an excellent opportunity to lead a consolidated research group. During my scientific career I have demonstrated creative thinking, autonomy and an excellent capacity to carry out state of the art research in heterogeneous catalysis, characterization, modelling and reactor engineering. I have a meritorious research track reflected by a good number of scientific publications, broad professional expertise, innovative project conception and a consolidate network of international collaboration. This, along with my leadership and management abilities, will assure the successful achievement of the mentioned goals of this project. HyMAP is a revised version of a proposal scored with A (2nd stage) of last ERC-CoG call.

Keywords: artificial photosynthesis,organic,inorganic semiconductors,computational chemistry,in situ characterization,solar photoreactor engineering,surface plasmon and up coversion nanoparticles
Demonstration of a High Definition Low Light Sensor (Starlight) for use in the Surveillance and Protection of Urban Soft Targets and Critical Infrastructures. (Starlight)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: United Kingdom
Call: Critical infrastructure protection topic 7: SME instrument topic: “Protection of Urban soft targets and urban critical infrastructures” (H2020-SMEINST-1-2014, 2014)
Start date: 2015-06-01
End date: 2015-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The security market and owners of urban soft targets and critical infrastructure, require high definition surveillance systems to monitor safety and security. Our innovative solution meets these needs by providing a value for money, light sensitive sensor that produces high definition images of non-illuminated areas at night and in low light conditions. Current technology suffers from poor light conversion and sensitivity therefore, to see at night and in low light conditions, the scene needs to be illuminated. Our proposal is to improve sensitivity by using sensors with organic compounds that are sensitive to background sky radiation (1.5 micron). We will also develop Application Specific Integrated Circuits to process the sensor output. The novelty in our innovation is the integration of new technologies and the processing of data produced by a 1.5 micron organic sensor. This will deliver high resolution images at night and in low light conditions. Our solution will reduce the energy required to illuminate urban soft targets and critical infrastructure. Added benefits include a reduction in light pollution and that surveillance can be carried out in areas which have lighting restrictions. The development of a proven, production ready system is the ultimate aim of the project. In Phase 1 we will carry out a feasibility study to verify the technological, practical and economic viability of our proposal. Our feasibility study will consider the results of relevant European and International research. We plan to further develop our prototype and carry out a small-scale demonstration of our innovative solution. The results of Phase1 will inform the direction of our future development activity in Phase 2. Our plan for full commercialisation of the project will be to market the product initially in Europe and extending this globally. The Phase1 report will form the basis of the proposal for further development activity and identify any issues to be addressed in Phase2.

Keywords: closed circuit television,organic sensors
The revolution of the Compression Therapy Market: an easy-to-wear and comfortable compression stocking based on Electro-Active Polymers technology. (ComFyt)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Israel
Call: Accelerating the uptake of nanotechnologies advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-06-01
End date: 2017-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

ComFyt is a novel compression therapy stocking employing a proprietary material which eliminates the discomfort and the difficulties of traditional compression stockings. ElastiMed has identified the potential of the technology in the method of manufacturing and processing Electro-Active Polymers (EAP). The material is a soft plastic, constructed flat, with large deformation and linear activation being a unique solution, optimal for wearable devices. These actuators are able to mimic the rhythmic natural calf muscle contractions, leading to the optimal blood circulation, representing a breakthrough in the Compression Therapy. Compression Therapy is based on a mechanical principle of applying a constant or intermittent pressure on the lower limbs using a wearable sleeve or stocking. Despite the many treatment options available, the market is suffering from a low compliance rate and continues to seek innovative solutions that will reduce patient’s discomfort, decrease hospitalization stay, and improve the patient quality of life. Venous and lymphatic diseases such as Venous Thromboembolism (VTE), Chronic Venous Insufficiency (CVI), Deep Vein Thrombosis (DVT) and Lymphedema affect a large population worldwide. Age, gender, heredity, pregnancy and lifestyle are conditioning factors. Pain, mobility difficulties, reduced self-esteem, social isolation, disability to work, altered body image and depression affect the quality of life of the elderly and in general of people coping with venous and lymphatic diseases. Yearly, there are approximately 10 million cases of VTE worldwide. VTE-related events kill more people than AIDS, breast cancer, prostate cancer and motor vehicle crashes combined in Europe and U.S. A growing elderly and diabetic population are also key components in the incidence of venous diseases. In addition to disease burden, venous and lymphatic diseases cause significant global economic burden.

Keywords: aging well,wellbeing,electro active polymers eap
The Double Edged Role of Nitric Oxide and Hydrogen Peroxide in a Coral Symbiosis (DENOCS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-06-01
End date: 2019-07-01
Duration (months): 24.0
Total project cost (EUR): 212194.8
EU funding (EUR): 212194.8
Participants: 1
Project status: CLOSED

Global climate changes affect coral reefs worldwide and these valuable marine biodiversity hotspots are increasingly experiencing a symbiotic dysfunction known as coral bleaching, where the global bleaching events in 2016 are the most significant to date. The underlying physiological mechanisms inducing the bleaching response remain unclear. It is known that cellular oxidative stress and reactive species such as nitric oxide (NO) and hydrogen peroxide (H2O2) are involved, but the sources and sinks of these compounds, their interplay and spatio-temporal dynamics have not been investigated in corals, partly due to lack of suitable experimental tools. The DENOCS projects will apply a suite of novel quantitative assessment techniques to investigate the dynamics and impact sites of NO and H2O2 in intact corals, coral tissue culture, and isolated photosymbionts when subjected to experimental treatments mimicking global change-induced environmental stress scenarios. This will encompass expert training of Dr. Schrameyer in the use of novel microsensors for NO and H2O2 in combination with advanced bioimaging of the oxidative and nitrosative stress response in corals, variable chlorophyll fluorescence imaging and cellular 14C-fixation assays to assess symbiont photosynthesis. Prospective outcomes of DENOCS include a better understanding of oxidative and nitrosative stress responses in corals, quantification of threshold concentrations and impact sites of reactive oxygen and nitrogen species, and how these are involved in the coral bleaching response. The project DENOCS will promote EU’s research and innovation excellence through its interdisciplinary measurement approach and international collaboration, and will enable the restart of a promising career of Dr. Schrameyer after a maternity break.

Keywords: coral symbiosis,photosynthesis,nitric oxide,hydrogen peroxide,oxidative stress,stress response,global change,signaling,coral bleaching,microenvironmental,microanalytical techniques
Role of individual retinal ganglion cell types in visual computation and behaviors (IndiVISUAL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 212194.8
EU funding (EUR): 212194.8
Participants: 1
Project status: CLOSED

The nervous system contains thousands of morphologically and physiologically different neuronal cell types, organized in distinct circuits. Information processed by the retina is streamed into more than 10 retino-recipient brain regions through approximately 20 distinct visual channels, originating in retinal ganglion cell types. One key feature of visual processing is significant convergence and divergence of retinal ganglion cell type inputs to different brain regions. The objective of this proposal is to understand the relevance of this convergence and divergence of visual pathways. Recently, we have identified several Cre transgenic mouse lines in which labeled ganglion cells show a mosaic-like distribution pattern of ganglion cell bodies in the retina and restricted axonal projections in the retino-recipient layers of the lateral geniculate nucleus, superior colliculus, and accessory optic system. Utilizing these new cell-type-labeled mouse lines, we will first characterize the morphological and physiological properties of Cre-expressing cell types. Next, we will silence or activate the synaptic release of individual cell types at a selective terminal region, such as the visual cortex and superior colliculus, using pharmacogenetic and optogenetic tools, and test their effects on light responses by in-vivo two-photon imaging. Finally, we will investigate the effects of silencing and activation of individual synaptic terminals on behaviors that it has been proposed are mediated by specific visual pathways: visual discrimination mediated by the retino-geniculate pathway; innate escape and approach behavior by the superior colliculus; and visually evoked compensatory head and eye movements by the accessory optic pathway. We aim to link, for the first time, individual pathways of ganglion cell type function with visual computation and behavior in order to gain mechanistic insights into how neuronal circuits are functionally organized in our brain.

Keywords: retinal ganglion cell,superior colliculus,visual cortex optogenetics,pharmacogenetics,behavior
ERA-NET: Sustained collaboration of national and regional programmes in cancer research (TRANSCAN-3)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Understanding health, wellbeing and disease
Action type: ERA-NET Cofund
Partnership: TRANSCAN-3 (ERA-NET)
Countries involved: Spain,Spain,Estonia,Italy,Austria,Germany,Ireland,Italy,Israel,Germany,Italy,Taiwan, Province of China,Norway,Greece,Hungary,Poland,Türkiye,Belgium,Romania,Slovakia,Latvia,France,France,Portugal,Canada
Call: ERA-NET: Sustained collaboration of national and regional programmes in cancer research (H2020-SC1-2020-Single-Stage-RTD, 2020)
Start date: 2021-03-01
End date: 2026-02-28
Duration (months): 60.0
Total project cost (EUR): 34081623.0
EU funding (EUR): 10949935.59
Participants: 32
Project status: SIGNED

Cancer is a worldwide health burden and a major public health challenge. Despite significant advances in the understanding, prevention, diagnostics and treatment, cancer remains a public health problem in Europe and the world. In such a setting, translational cancer research plays a key role in successfully addressing the growing burden of cancer. The great potential of translational cancer research in Europe will only be achieved when the main barriers are systematically addressed through concerted actions between public and private organisations that provide funds for research, researchers, healthcare providers and all those engaged in the cancer research spectrum. Moreover, adequate and systematic financial support backed by a strong political commitment is absolutely essential to help reduce the burden of cancer that European citizens are currently facing. In this context, the TRANSCAN-3 network, with a strong background in funding cancer research, embodies an excellent model of cross-national cooperation by bringing together 31 funding organisations, from 20 countries, with the common goal of supporting high-impact translational cancer research through cross-national joint calls for proposals, and by an efficient investment of dedicated national/regional public funding, leveraged with foundation/charity-based resources and EU financial support. Building up on the well-established cooperation and accomplishments, through the harmonisation of national/regional funding mechanisms and programmes, plus continued and sustained series of efforts for the access to and sharing of data on cancer research, this TRANSCAN-3 project also aims at becoming a catalysts for a sustainable model of funding of high-impact cancer research in Europe and beyond, with an approach to effectively engage relevant stakeholders (patients, society as a whole, policy makers, etc.) in different stages of the action.

Keywords: translational cancer research,cancer research funding,transnational calls for research proposals,cancer prevention and treatment,national and regional cancer programmes
SENIOR BIOMECHANICAL 3D MODELLING RESEARCHER (BioMech-3D)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Lithuania
Call: European SME innovation Associate - pilot (H2020-INNOSUP-2019-02, 2019)
Start date: 2019-12-31
End date: 2020-12-30
Duration (months): 12.0
Total project cost (EUR): 80125.0
EU funding (EUR): 80125.0
Participants: 1
Project status: CLOSED

Aim of this project is to develop surgeon-friendly 3D biomechanical simulation functionality as integral part of 3D models-based pre-operational planning software for evaluation of implant positioning to the movement axis of the neighbouring joints and the load distribution in the bone / implant contact zones in a risk-free environment. Therefore, Ortho Baltic is looking for a researcher with competence in clinical and computational biomechanics to join the research team in the development of cutting-edge 3D model-based pre-surgery planning software with 3D user interface via Web browser. Recruited innovation associate would work as part of Ortho Baltic R&D team developing state-of-the-art 3D model-based pre-surgery planning tools by integrating human musculoskeletal simulation and Finite Element Analysis (FEA) functionalities. Innovation associate would be Senior biomechanical researcher, who will work in multidisciplinary team of our R&D unit and in cooperation with Ortho Baltic academic partners, keeping direct contact with leading surgeons to mitigate fundamental research into fieldable technology and deployable products.

Keywords: biomechanics,biomechanical modelling,3d modelling,joint replacement,pre operational planning,biomechanical musculoskeletal modelling,senior biomechanical researcher
Stable and High-Efficiency Perovskite Light-Emitting Diodes (SHINING)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Sweden
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-03-01
End date: 2022-02-28
Duration (months): 60.0
Total project cost (EUR): 1499759.0
EU funding (EUR): 1499759.0
Participants: 1
Project status: CLOSED

Light-emitting diodes (LEDs), which emit light by a solid-state process called electroluminescence, are considered as the most promising energy-efficient technology for future lighting and display. It has been demonstrated that optimal use of LEDs could significantly reduce the world’s electricity use for lighting from 20% to 4%. However, current LED technologies typically rely on expensive high-vacuum manufacturing processes, hampering their widespread applications. Therefore, it is highly desirable to develop low-cost LEDs based on solution-processed semiconductors. A superstar in the family of solution-processed semiconductors is metal halide perovskites, which have shown great success in photovoltaic applications during the past few years. The same perovskites can also been applied in LEDs. Despite being at an early stage of development with associated challenges, metal halide perovskites provide great promise as a new generation of materials for low-cost LEDs. This project aims to develop high-efficiency and stable perovskite LEDs based on solution-processed perovskites. Two different classes of low-dimensional perovskites will be investigated independently. These new perovskites materials will then be coupled with novel interface engineering to fabricate perovskite LEDs with the performance beyond the state of the art. At the core of the research is the synthesis of new perovskite nanostructures, combined with advanced spectroscopic characterization and device development. This project combines recent advances in perovskite optoelectronics and low-dimensional materials to create a new paradigm for perovskite LEDs. This research will also lead to the development of new perovskites materials which will serve future advances in photovoltaics, transistors, lasers, etc.

Keywords: perovskites,light emitting diodes,optoelectronics