Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Using biotechnology to create the next generation of sustainable foods from the roots of mushrooms (Mushlabs)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2022-11-01
End date: 2024-10-31
Duration (months): 24.0
Total project cost (EUR): 3467500.0
EU funding (EUR): 2426375.0
Participants: 1
Project status: CLOSED

Mushlabs is a biotech company that produces meat replacement from mushroom roots called mycelium. We have developed our proprietary fermentation technology to create mushroom biomass: a meat replacement ingredient revolutionizing plant-based alternative proteins. Our mission is to change the way people eat by producing tastier, healthier and more sustainable foods. We take pieces of (mycelium) and cultivate them in a controlled and optimal environment. These serve as the “seed” for the mushroom biomass we harvest. We feed the mycelium with side streams of agro-and food industries. In large bioreactors, the mushroom mycelial cells ferment the side streams and multiply. This biological process accumulates biomass rich in protein, dietary fiber and micronutrients with a savoury flavour, which serves as the main raw ingredient for all of our products. With very few ingredients and little food processing we create delicious, healthy and sustainable everyday foods that replaces meat.

Keywords: biomass,circular process,mycelium,plant based meat replacement
Designing better genetics across crops using CRISPR technology to build climate change resilient crops (EDGETM)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 30.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Modern agriculture faces multifaceted challenges, including the impacts of climate change, evolving pests and diseases, genetic uniformity in crops, regulatory complexities for genetically modified crops, and market volatility. These challenges pose significant threats to crop yields, financial stability for farmers, and global food supply chains. Overcoming these obstacles is imperative for the sustainable and resilient future of agriculture. BetterSeeds introduces a revolutionary solution to the challenges hindering progress in crop improvement through genome editing. Our proprietary technology, Efficient Delivery of Gene Editing (EDGE), overcomes bottlenecks in genetic transformation and plant regeneration. Utilizing viral vectors for CRISPR component delivery throughout the plant, EDGE offers unprecedented versatility across diverse hosts, eliminating the reliance on traditional tissue culture methods. Redesigning viral genomes and fragmenting CRISPR machinery enable EDGE to overcome limitations in viral payload size. This technology allows for precise genetic modifications in crops, enabling the development of varieties with heightened resistance to climate stresses, diseases, and improved nutritional profiles. The core values of BetterSeeds lie in providing farmers and end users with climate-resilient, disease-resistant, and nutrient-enriched seeds. Through a diverse seed portfolio and cutting-edge technology, BetterSeeds emerges as a leader in ushering agriculture into a more sustainable and productive future.

Keywords: crispr technology,precision agriculture,biotechnology,plant genetics,botany
DIGITALISATION FOR AGROECOLOGY (D4AgEcol)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Coordination and support actions
Countries involved: Germany,Finland,Portugal,United Kingdom,Greece,Denmark,Austria
Call: Digitalisation as an enabler of agroecological farming systems (HORIZON-CL6-2021-FARM2FORK-01, 2021)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 1838805.0
EU funding (EUR): 1788059.5
Participants: 12
Project status: SIGNED

D4AgEcol will show the potentials of digitalisation as enabler for agroecological farming systems in Europe based on available knowledge and actors' and stakeholders' co-innovation capacity . Partners from seven countries across a wide spectrum of pedoclimatic zones in Europe will assemble a holistic evaluation of digital tools and technologies. This will be based on indicators for agroecology, economic considerations and investigations about perceived benefits for user and stakeholder. Drivers, barriers and risks of digital technologies for a transformation towards agroecology will be identified. The results of this analysis will feed in national and European roadmaps for agroecology, indicating the need for adjusted policies and a technology research and innovation agenda.

Keywords: precision farming,agricultural economics,adoption of innovations
Participatory Open Social Innovation Through Interlinking Valuable Ecosystems (POSITIVE)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Interconnected Innovation Ecosystems
Destination: Interconnected Innovation Ecosystems
Action type: Coordination and support actions
Countries involved: Germany,Italy,Lithuania
Call: Integration of social innovation actors in innovation ecosystems (HORIZON-EIE-2022-CONNECT-01, 2022)
Start date: 2023-02-01
End date: 2024-11-30
Duration (months): 22.0
Total project cost (EUR): 553583.17
EU funding (EUR): 499982.81
Participants: 6
Project status: CLOSED

Social innovation actors take on an important role in finding solutions for societal challenges. However, many social enterprises lack entrepreneurial skills and digitization of their products or services and there is still a lack of support for social entrepreneurs, which is due to the fact that many business support organisations have little understanding of the specific challenges and needs of social entrepreneurs. The social innovation and the technology innovation ecosystems are currently not well interconnected and mostly considered separate ecosystems with different skillsets. The POSITIVE project will counteract these factors by raising awareness about the benefits of social innovation and providing capacity building about social innovation and social entrepreneurship to the tech innovation ecosystem, thus creating the basis for better support for social entrepreneurs and a more inclusive innovation ecosystem based on mutual understanding. The project will also provide new opportunities for social entrepreneurs to digitise their products and services and to acquire new business skills through the organisation of an Open Innovation Challenge in three countries (POSITIVE Impact Challenge), which constitutes knowledge transfer from the tech into the social innovation ecosystem, with the specific purpose to support regional SI actors to access alternative means of financing. The POSITIVE project will also foster the interlinkage of the two ecosystems on a regional and European level through cross-fertilization, knowledge exchange and policy recommendations on how the POSITIVE Impact Challenge model can be replicated. Thus, the POSITIVE project can not only contribute to the strengthening of the social economy on different levels, but also make the tech innovation ecosystem more resilient and equipped to tackle the important societal challenges by including social innovation actors.

Keywords: innovation ecosystems open innovation open social innovation innovation challenge impact knowledge transfer,training,capacity building,synergies
Paving the way for an ABS recycling revOLution in the EU (ABSolEU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: France,Norway,Sweden,Denmark,Netherlands,Belgium,Portugal
Call: Paving the way to an increased share of recycled plastics in added value products (RIA) (HORIZON-CL4-2021-RESILIENCE-01, 2021)
Start date: 2022-06-01
End date: 2026-05-31
Duration (months): 48.0
Total project cost (EUR): 8078863.75
EU funding (EUR): 8078862.0
Participants: 13
Project status: SIGNED

ABSolEU aims to pave the way to circularity for the ubiquitous plastic ABS, found in durable products from toys and other consumer goods to automotive components. Despite the potential of this material, at least 85% of end-of-life ABS ends up in landfills or incineration due to the presence of additives and fillers that hamper its proper recycling. ABSolEU will develop and mature to TRL 6 a technology for the physical recycling of waste ABS, providing a clean and safe recyclate that is free of additives and contaminants and ready to be reintroduced into the value chain for value added, high performance products. In parallel, ABSolEU will develop new analytical methods for safety and quality assurance; these will allow project partners to establish a thorough understanding of the composition of ABS waste streams, including the presence of additives and the degree of degradation, as well as monitor these throughout recycling and compounding processes. In addition, ABSolEU aims to provide the scaffolding to support adoption of physical recycling for ABS and support the uptake of ABS recyclates by industry and consumers. This is achieved through circular value chain labs and explorative citizen labs, investigation of new traceability systems for ABS materials and products, and standardisation of processes for recycling, analysis and traceability. ABSolEU?s research outputs are communicated, disseminated and synthesised into best practices, methodologies, and policy recommendations for ABS recycling to contribute to a resource efficient industry. The project is implemented by a strong consortium that spans the entire ABS value chain. It is led by UCA and involves 10 additional partners: 3 global brand owners, 2 RTOs, an ABS-producing company, a recycler, a traceability solutions company, a standardisation institute and a company specialised in stakeholder engagement. With ABSolEU, the consortium is seeking to lay the first bricks of a sustainable future for ABS plastics.

Keywords: physical recycling,standardisation,traceability,characterisation of plastic recyclate,abs,quality control
Novel subglacial ocean models to accurately predict Ice-shelf Ablation rates at high resolution and low computational cost (IceAblation)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-07-01
End date: 2029-06-30
Duration (months): 60.0
Total project cost (EUR): 1497861.0
EU funding (EUR): 1497861.0
Participants: 2
Project status: SIGNED

Ice shelves fringing the Antarctic coastline limit sea-level rise by slowing down the flow of grounded ice into the sea. They are thinning because of warming and intensifying ocean currents. Building upon my expertise in multi-scale flow dynamics and subglacial oceanography, I will resolve the two main bottlenecks that impair our ability to assess and project the state of Antarctic ice shelves. These are: (i) a poor understanding of the relationship between ice-shelf ablation rates and ocean properties & (ii) the high computational cost of ocean simulations. I will first build new models of the metre-thick ice-shelf—ocean boundary layer (ISOBL), using innovative laboratory experiments and simulations that will unravel its dynamics. The lack of accurate ISOBL models is responsible for leading-order errors in predicting ice loss rates and freshwater production. The new models will capture how turbulence controls heat fluxes over an unprecedented range of sub ice-shelf conditions, accurately predicting ice ablation rates from the grounding line to the shelf front. I will then promote a paradigm shift in the modelling of oceans beneath ice shelves, which are hundreds of kilometres wide. At present, ensemble simulations of ice-shelf ocean cavities on 100-year time scales are about 1000 times computationally too costly to resolve mesoscales, which influence the mean circulation and ice ablation. To circumvent this issue, I will train novel data-driven reduced-order models (ROMs), which will emulate the ocean dynamics at high resolution and unprecedently low computational cost. The ROMs will learn the key fingerprints of ocean cavities and their time evolution from short-term high-resolution simulations. They will then be extended to longer times and different forcing conditions, enabling eddy-resolving IPCC-level large ensemble simulations of subglacial oceans, which will help reduce uncertainty related to the timing of abrupt regime changes of the Antarctic ice sheet.

Keywords: subglacial oceanography,turbulence,ice shelves,boundary layers,large scale flows,mesoscales,melting and dissolution,direct numerical simulations,laboratory experiments,data driven reduced order models,subgrid scale parameterization,ice sheets,sea level rise,climate change
Carbon-Hydrogen bond activation via a new charge control approach (C-HANCE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Austria
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 2750000.0
EU funding (EUR): 2750000.0
Participants: 1
Project status: SIGNED

Organic synthesis stands as the beating heart of technological and societal advancement, driving breakthroughs in drug discovery, agrochemistry, materials design, and the pursuit of a more sustainable world. In a world where C–H bonds are the main functional groups available, the field of C–H functionalisation has experienced exponential growth over the past two decades. While state-of-the-art methods have led to remarkable achievements, they remain confined by the dominance of substrate-controlled reactions driven by directing group logic, and by being largely reliant on precious metal catalysts. C-HANCE proposes to open a new page in C–H functionalisation, exploiting the emerging concept of charge control as a mode to influence and steer reactivity of C–H bonds. This will usher in a new logic for C–H bond functionalisation, where reagent control can address substrates devoid of directing groups and where entirely novel reactions will emerge. This will not only reshape our fundamental understanding of C–H functionalisation, but also yield valuable products for downstream applications. Given my unique expertise and documented track-record of achievements – especially in the exploration of out-of-the-box, non-mainstream fields of synthetic chemistry –, I am in a unique position to lead in the unfolding of this new era.

Keywords: organic synthesis,charge control,functionalisation,hydride,proton
Offspring coping abilities from stressed parents exposed to global warming in aquaculture and fisheries systems (CAPWARM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: CLOSED

Climate change is affecting the ecosystem’s resilience, biodiversity, productivity, and health. One major societal issue is to secure food destined for human consumption. Fish are the primary resource for essential fatty acids and proteins for billions of people and they contribute significantly to species diversity and functioning of marine, estuarine, and freshwater ecosystems. Yet, we are still limited in our ability to accurately predict how climate-change stressors will affect fish populations. To date, we are crucially lacking studies evaluating the impacts of climate change linking subfields of fish ecology such as genetics, behaviour, physiology, community dynamics or spatial ecology. Other essential aspects of climate-change impacts, such as cross-generational effects and sex-specific responses of parents that could adaptively prepare the offspring, are also often ignored. The proposed project has three main objectives: (1) investigate the effects of parental thermal stress on offspring’s coping abilities to face multiple climate stressors, (2) evaluate the impact of thermal stress on sex-specific response and decipher the sex-specific parental effects on the next generation, and (3) identify, in collaboration with stakeholders from aquaculture and fishery sectors, mitigation strategies that can mediate these effects. CAPWARM includes laboratory and field work on two valuable salmonid species for human consumption: the Rainbow trout, Oncorhynchus mykiss, and the Atlantic Salmon, Salmo salar. The first accounts for 60% of EU freshwater fish farming, while the second is the first produced marine fish but is paradoxically declared at risk in most European waters. The results will be further discussed along with management practices available to mitigate parental thermal stress, in both aquaculture and wild contexts. CAPWARM outputs will be of high importance for fisheries, aquaculture, and conservation and fits with the climate action top priority of the EU.

Keywords: climate change sex specific response parental specific contribution offspring coping abilities aquaculture fisheries salmonids physiology behaviour reproduction genetic molecular biology ecology
Colloidal Yielding: tunable glasses to explore plasticity from macroscopic to microscopic length-scales. (COLLY)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-01
End date: 2027-12-31
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 2
Project status: SIGNED

Upon external mechanical loading, amorphous solids initially deform elastically, but for large enough applied stress they may fracture or flow as a plastic fluid. This transition, known as yielding, is one of the most fascinating open problems in condensed matter statistical physics. In fact, the exact nature of the transition is still unclear: some systems show abrupt (brittle) yielding (e.g., in oxide glasses) while others, such soft gels or foams, display ductility with a smooth and gradual increase of plastic deformation. A unique picture of the processes at play is yet missing and recent models and theories claim experimental support. Here I will use a use a novel colloidal glass to explore the yielding transition and its properties. Colloidal glasses are controlled through their volume fraction: it plays the same role of temperature in molecular ones, but it is much more difficult to precisely tune. I will overcome this difficulty exploiting a mixture of nanoparticles and non-colloidal polymer mesogels. The mesogels swell/shrink as a function of temperature, controlling the available ‘free’ volume for the (temperature-insensitive) nanoparticles. This approach allows for an unprecedented precise control of the volume fraction in a colloidal glass without changing particle-particle interaction or their size (e.g., in microgels). The versatility of the system will be exploited to investigate plastic activity for different level of glass equilibration and external applied stresses thanks to cutting-edge experiments involving rheology, time- and space- resolved visible scattering and synchrotron-based X-ray photon correlation. These approaches will be combined to obtain a comprehensive picture of the processes at play, allowing for a ground-breaking study from inter-particle distances up to macroscopic sizes. The yielding transition will then be tackled from a new point of view, potentially elucidating its nature and confronting emerging theories.

Keywords: glasses,glass transition,elasticity,plasticity,yielding,x ray scattering,x ray photon correlation spectroscopy,xpcs,dynamic light scattering,photon correlation imaging,rheology,pnipam