Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
5G Communication with a Heterogeneous, Agile Mobile network in the Pyunchang wInter Olympic competioN (5G CHAMPION)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Finland,Finland,Belgium,France,France
Call: 5G – Next Generation Communication Networks (H2020-EUK-2016-1, 2016)
Start date: 2016-06-01
End date: 2018-05-31
Duration (months): 24.0
Total project cost (EUR): 2998517.5
EU funding (EUR): 2998517.5
Participants: 9
Project status: CLOSED

The 5G CHAMPION project ambitions to deliver the first 5G system proof-of-concept in conjunction with the 2018 South Korean Winter Olympics. Key novel 5G building blocks will be developed and implemented into a new architectural approach providing an efficient end-to-end system performance encompassing cutting edge 5G radio-access, core-network and satellite technologies. It will be the first time ever that state-of-the art terrestrial wireless communication, including future key enablers such as mmWave access, will be seamlessly combined with a disruptive satellite communication, forming a ‘multi RAT capable’ 5G network optimised to serve user equipment in various deployment context. The novel building blocks will rely on innovations in RF, antenna and radio protocols design for mmWave access and backhaul network, efficient virtualization through NFV/SDN functions enabling a flexible packet core implementation and satellite based communication and navigation solutions for extended coverage and ubiquitous high precision location estimation. Emphasize is furthermore laid on an efficient standardization strategy and on the resolution of key certification hurdles. The proposed technologies will finally be improving Latency in the ms range and provide high throughput in very dense user environment, cost effective network management, QoS improved in high speed mobility conditions, high precision/integrity location and timing estimation, ubiquitous service provisioning as well as flexibility in equipment reconfiguration through software which are listed among the main challenges for the design of the 5G network. These technologies are of particular interest for High speed mobile broadband and Internet of things and the respective integration of heterogeneous technologies in a common framework.

Keywords: 5g proof of concept,dynamic beamforming,backhaul,network virtualization,olympic demonstrations,mmwave access,mobile broadband,high velocity v2x channels,moving hot spots,link tracking
Collisional excitation of interstellar molecules: towards reactive systems (COLLEXISM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: France,France
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-07-01
End date: 2025-06-30
Duration (months): 72.0
Total project cost (EUR): 1802625.0
EU funding (EUR): 1561804.34
Participants: 3
Project status: SIGNED

Accurate determination of physical conditions of interstellar molecular clouds is a crucial step to better understand the life cycle of the interstellar matter and particularly the formation of stars and planets as well as the synthesis of organic molecules that may lead to emergence of life in the universe. A key parameter for the determination of these conditions from interstellar spectra is the calculation of accurate collisional rate coefficients of interstellar molecules with the most abundant species (H, He, H2 and e-). Whereas the knowledge of collisional processes has reached a certain level of maturity for collisions involving non-reactive molecules, very few reliable data exist for collisions involving reactive radicals and ions. The computation of such data is a real challenge since inelastic and reactive processes compete during collisions. In this project, we plan to overcome this complex problem and to provide collisional data for these radicals and ions in order to derive as much information as possible from the molecular spectra collected by current telescopes. As it is hardly possible to consider both collisional and reactive processes simultaneously, we will set up a new methodology based on quantum approach that allows obtaining accurate data. We will focus on molecular hydrides that are good candidates because of both their astrophysical importance and their quantum accessibility. We will carry out the determination of interaction potentials using quantum chemistry ab initio methods while the treatment of the dynamics of the nuclei will primarily be done using quantum time-independent reactive and non-reactive approaches. When exact quantum calculations will not be usable, innovative statistical quantum mechanical methods will also be explored. The new data will then be used in radiative transfer models and the predictions will be finally compared to observations in order to derive the abundances of reactive radicals with unprecedented accuracy.

Keywords: laboratory astrophysics,collisional rate coefficients,molecular abundances,radiative transfer
Microbial Conlonization in Confined Chaotic Mixtures (MicroMix)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-05-01
End date: 2022-08-06
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

Subsurface bacteria represent a fundamental, yet poorly known, component of the Earth’s biosphere. These communities are key in biogeochemical cycles and in a range of problems in Environmental and Geosciences, ranging from water resources management and bioremediation, to CO2 sequestration and geothermal energy. Until recently, the opacity of 3D porous media-the natural habitat of subsurface bacteria-had prevented in situ and in vivo imaging of bacterial dynamics in such environments. Recent experimental and theoretical breakthroughs at the host institution have led to the discovery that flows in natural porous media are chaotic in nature. Since chaotic mixing is known to yield and sustain strong chemical gradients at micro-scale, this discovery challenges the assumption of homogeneous nutrient distributions, broadly-used in current models of subsurface microbial processes. The goal of MicroMix is thus to explore the effect of chaotic mixing on bacterial growth and colonization in 3D porous media under positive stimuli (WP1: mixing-limited nutrient resources) and negative stimuli (WP2: antibiotic source, nutrient rerouting by bioclogging). To do so, we will develop a novel bioreactor system, primarily based upon coupling high-resolution Laser Induced Fluorescence and optical index matching, which will allow us to obtain the first joint imaging of chemical landscapes and bacterial colonies in 3D porous media. The project builds upon the combined expertise of the ER in the field of biomicrofluidics, of the supervisor in mixing dynamics, and of the secondment supervisor on biofilm dynamics in porous media. Through a detailed career development plan, a tailored training program and access to key experimental facilities and scientific networks, MicroMix will ensure an efficient re-integration of the ER and place him at the forefront of research on environmental fluid dynamics.

Keywords: porous media,bacteria,chaotic mixing,biofilm,solute transport,microfluidics
Mercurius Connect (Mercurius Connect)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Portugal
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-01-01
End date: 2019-06-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Cancer is one of the most deadly diseases on the planet and radiotherapy (RT), a pillar treatment in the fight against it. Imagine that patients from all over the world could have access to the most specialized RT professionals and that waiting times for treatment could be diminished. This is what we are proposing with Mercurius Connect platform, a Gig economy marketplace where RT Centres can find highly specialised dosimetrists, from all over the world, to perform clinical dosimetries on demand. The creation of a clinical dosimetry, a treatment plan, that determines a set of radiation fields, which will deliver the prescribed radiation dose to a delimited tumour volume, while minimizing the impact on surrounding tissue/organs, is one of the most complex and time-consuming tasks in RT. Mercurius Connect provides to RT Centres the possibility to get a high-quality service, while diminishing inefficiencies related with over or underestimation of the number of required professionals. On the other hand, the solution offers to RT Centres in low-and-middle-income countries, access to highly specialised radiotherapy professionals, where the lack of these resources is a huge challenge.

Keywords: marketplace,radiotherapy,dosimetry
Joint European Research Infrastructure of Coastal Observatories: Science, Service, Sustainability - JERICO-S3 (JERICO-S3)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Integrating activities and infrastructures
Action type: Research and Innovation actions
Countries involved: Spain,Estonia,Italy,Spain,Spain,Spain,Germany,Germany,Germany,Spain,Ireland,Italy,Italy,Germany,Belgium,Sweden,Norway,Norway,Finland,Greece,Croatia,Belgium,France,France,France,France,France,France,France,Netherlands,Netherlands,Faroe Islands,United Kingdom,Denmark,Portugal,United Kingdom
Call: Integrating Activities for Advanced Communities (H2020-INFRAIA-2019-1, 2019)
Start date: 2020-02-01
End date: 2024-01-31
Duration (months): 48.0
Total project cost (EUR): 9999933.96
EU funding (EUR): 9999933.55
Participants: 45
Project status: SIGNED

amJERICO-RI: Joint European Research Infrastructure of Coastal Observatories – a system of systems strengthening the European network of coastal observatories providing a powerful and structured European Research Infrastructure (RI) dedicated to observe and monitor the complex marine coastal seas and to: (i) provide services for the delivery of high quality environmental data, (ii) access to solutions and facilities as services for researchers and users, (iii) create product prototypes for EU marine core services and users, (iv) support excellence in marine coastal research to better answer societal and policy needs. JERICO-S3 will provide a state-of-the-art, fit-for-purpose and visionary observational RI, expertise and high-quality data on European coastal and shelf seas, supporting world-class research, high-impact innovation and a window of European excellence worldwide. It will significantly enhance the current value and relevance of the JERICO-RI, through the implementation of the science and innovation strategy elaborated as part of the JERICO-NEXT project. JERICO-S3 is mainly targeting a more science integrative approach to better observe the coastal ecosystem, raising up the scientific excellence, with consideration of the regional and local ecosystems; the preliminary development of an e-infrastructure in support to scientists and users by offering access to dedicated services; progress on the design of the RI and its strategy for sustainability. Major user-driven improvements will be realised in terms of observing the complexity of coastal seas and continuous observation of the biology, access to facilities, data and services, best practices and performance indicators, innovative monitoring strategies, cooperation with other European RIs (EuroARGO, EMSO, AQUACOSM, DANUBIUS, ICOS, EMBRC, LIFEWATCH) and international scientific communities, industry and other stakeholders, and aligning strategy with COPERNICUS/CMEMS, EMODNET and GEO/GEOSS.

Keywords: coastal observation,research infrastructure,marine ecosystem health,innovative monitoring,high impact services,integrative approach,harmonization,scientific excellence,strategy,sustainability
An integrative strategy of testing systems for identification of EDs related to metabolic disorders (OBERON)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Understanding health, wellbeing and disease
Action type: Research and Innovation actions
Countries involved: Spain,Spain,Italy,Germany,Greece,France,France,France,France,France,Czechia
Call: New testing and screening methods to identify endocrine disrupting chemicals (H2020-SC1-2018-Single-Stage-RTD, 2018)
Start date: 2019-01-01
End date: 2023-12-31
Duration (months): 60.0
Total project cost (EUR): 6814644.5
EU funding (EUR): 5978762.5
Participants: 15
Project status: SIGNED

Exposure to chemical substances that can produce endocrine disrupting effects represents one of the most critical public health threats nowadays. In line with the regulatory framework implemented within the European Union to reduce the levels of endocrine disruptors (EDs) for consumers, new and effective methods for ED testing are needed. The OBERON project will build an integrated testing strategy (ITS) to detect EDs-related metabolic disorders by developing, improving and validating a battery of test systems. It will be based on the concept of an integrated approach for testing and assessment (IATA). OBERON will combine 1) experimental methods (in vitro e.g. on 2D and 3D human-derived cells and tissues, and in vivo i.e. in zebrafish at different stages), 2) high throughput omics technologies, 3) epidemiology and human biomonitoring studies and 4) advanced computational models (in silico and systems biology) on functional endpoints related to metabolism. Such interdisciplinary framework will help at deciphering EDs based on mechanistic understanding of toxicity by providing and making available more effective alternative test methods relevant for human health that are in line with regulatory needs. Data generated in OBERON will also allow the development of novel Adverse Outcome Pathways (AOPs). The assays will be pre-validated in order to select the test systems that will show acceptable performance in terms of relevance for the second step of the validation process, i.e. the inter-laboratory validation as ring tests. Therefore, the aim of the OBERON project is to support the OECD conceptual framework for testing and assessment of EDs by developing specific assays not covered by the current tests, and to propose an IATA approach for ED-related metabolic disorders detection, which will be submitted to the JRC and OECD community.

Keywords: iata,integrated testing strategy,endocrine disruptors,metabolics disorders,systems toxicology,molecular mechanisms,aops,computational modelling,omics,epidemiology,zebrafish,human cells
Integration of herpesvirus into telomeres: From the mechanism of genome integration and mobilization to therapeutic intervention (INTEGHER)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Germany
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-04-01
End date: 2022-03-31
Duration (months): 72.0
Total project cost (EUR): 1810747.0
EU funding (EUR): 1810747.0
Participants: 1
Project status: CLOSED

Herpesviruses cause serious diseases in humans and animals. After initial lytic infection, herpesviruses establish a quiescent (latent) infection, which allows their persistence in the host for life. We and others recently identified a novel mechanism that allows maintenance of the genome of certain herpesviruses during latency, by integrating their complete genetic material into host telomeres. One of these viruses is human herpesvirus 6 (HHV-6) which is associated with seizures, encephalitis, and graft rejection in transplant patients. Sporadic reactivation of the integrated virus ensures continued evolution of the virus as it spreads to a new cadre of susceptible individuals. There are critical gaps in our knowledge regarding the fate of herpesvirus genomes during integration and reactivation as well as of viral and cellular factors involved in these processes. INTEGHER will make use of novel technologies to close these gaps and to devise new therapeutic approaches. Specifically, we will 1) determine the fate of the HHV-6 genome during latency by developing a novel reporter system that allows live-cell imaging of the virus genome in living cells and elucidate epigenetic changes of the HHV-6 genome during integration and reactivation; 2) identify viral and cellular factors that drive virus genome integration and reactivation, using recombinant viruses, drugs and CRISPR/Cas9 genome engineering 3) employ genome-editing tools to eliminate the virus genome integrated in host chromosomes in vitro and in an in vivo model. The proposal utilizes state-of-the-art technologies and pioneers new approaches, particularly with regard to visualization and excision of virus genomes in latently infected cells that are also present in (bone marrow) transplants. Altogether, these studies will define the mechanism of herpesvirus integration and reactivation and will provide new tools for therapeutic excision of virus genomes from living cells.
Engineering a solution to the “resolution gap” problem for probing local optoelectronic properties in low-dimensional materials (AETSOM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Israel,United States
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-09-01
End date: 2024-08-31
Duration (months): 36.0
Total project cost (EUR): 269998.08
EU funding (EUR): 269998.08
Participants: 2
Project status: SIGNED

Many of the defining optoelectronic properties in low-dimensional materials – e.g. exciton Bohr radii and diffusion lengths, defect sizes and spacings, and Moire lattice periods – are determined by materials physics and processes that occur at the single-digit nm length scale. Their direct investigation and elucidation – crucial for future applications – therefore requires the ability to probe light-matter interactions at a resolution an order of magnitude better than what is generally achievable with existing nano-optical approaches. Here we propose a strategy for achieving single-nm optical resolution by developing a breakthrough capability which we will refer to as Atomic Energy Transfer Scanning nano-Optical Microscopy (AETSOM). The one-nm optical resolution will be attained by the attachment of a lanthanide-doped upconverting nanoparticle (UCNP) at the end of a near-field scanning probe tip. The intended probe is composed of a tapered metal-insulator-metal waveguide fabricated at the end of a glass fiber, enabling the efficient coupling of far-field light to the near-field and vice-versa through the probe tip, over a wide range of wavelengths. Lanthanide-doped UCNPs absorb multiple photons in the NIR and emit at higher energies in the NIR/visible with efficiencies orders of magnitude higher than those of the best 2-photon fluorophores. The robust attachment of the UCNPs to the probe through specific functionalization of the UCNPs will enable illumination/collection to/from single-digit nm volumes. The establishment of this breakthrough single-digit nano-optical capability will provide the ability to perform photon-based characterization and activation over multiple length scales on nearly any sample and in the real environments encountered in most technological applications. The anticipated results will immediately impact numerous fields, from quantum materials to photo-chemistry to energy harvesting to ultrasensitive biomolecular control and detection.

Keywords: nano optics,nano photoluminescence,optoelectronics,layered 2d materials,quantum materials,defects
Past and present colour symbolism among African hunter-gatherers. (AH-GCOLSYM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

I plan to investigate colour symbolism among African hunter-gatherers (AHGs), using the results to help interpret findings of my previous archaeological research on southern African pigment use before, during, and after our morphologically diagnosed speciation. Having previously shown that earth pigments were primarily chosen for their saturated redness and/or sparkling brilliance, I am interested in discovering the part played by similar perceptual properties in the cosmological systems and rituals of AHGs whose voices can inform us today. AHGs are distinguished by high levels of gender egalitarianism, including the coexistence of women’s rituals alongside those of men, often in ways which augment women’s solidarity and power. One aim, therefore, will be to investigate the use of coloured substances in ritual performances and how this relates to broader cosmology and gender dynamics. I will also undertake structuralist analysis of selected myths where similar percepts play a significant role (having access to a previously unpublished store of narratives which can be analyzed in these terms). While attentive to ethnographic detail, I will go beyond mere description, drawing on current theoretical frameworks addressing either our emergence in Africa as a symbolic species or colour symbolism in myth and ritual, investigating whether any of them make sufficiently detailed predictions to test in the light of my findings. I hope to publish my results in three peer-reviewed scientific papers. Within the MSCA Work Programme, the project is relevant to the societal challenge of inclusive, innovative and reflective societies. Modern human origins research attracts high levels of public interest, but has suffered from low levels of cultural sensitivity or self-awareness. Bringing the insights of social anthropology to bear on our emergence in Africa as a symbolic species is intended to help remedy this.

Keywords: earth pigments,middle stone age,speciation,analogy,hypothesis testing