Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Cybersecurity Awareness and Knowledge Systemic High-level Application (YAKSHA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Spain,Italy,Thailand,Greece,Greece,Finland,Malaysia,Bulgaria,France,France,Viet Nam,Portugal
Call: International partnership building in low and middle income countries (H2020-ICT-2017-1, 2017)
Start date: 2018-01-01
End date: 2020-12-31
Duration (months): 36.0
Total project cost (EUR): 2481983.75
EU funding (EUR): 1989599.37
Participants: 16
Project status: CLOSED

YAKSHA aims at reinforcing EU-ASEAN cooperation & building partnerships in the cybersecurity domain by developing a solution tailored to specific user and national needs, leveraging EU Know-How and local expertise. YAKSHA will develop and introduce the innovative concept of honeypots-as-a-service which will greatly enhance the process of gathering threat intelligence. It will enhance cybersecurity readiness levels for end users, help prevent cyber-attacks, mitigate cyber risks and better govern the whole cybersecurity process. YAKSHA is ideally positioned to secure global manufacturing supply chains, given its planned focus on IoT Security. YAKSHA will develop innovative methods for malware detection, collection and analysis, as well as design a specialised ontology to be used for long-term storage and analysis of the information, and deploy standard information formats and interfaces to facilitate interoperability. The YAKSHA software solution will be validated in real-world pilot projects in both regions, focusing on Vietnam & Greece, but with plans to expand the deployments to other countries. The test cases will be represented by complex end-users with articulated cybersecurity risks and will allow the consortium to gather feedback to be used later to bring the solution to the market. YAKSHA will develop a comprehensive business plan for the transition of the solution and complementary services to TRL9, leveraging the very strong ASEAN partners that are members of the consortium - including governmental organisations and leading end-users communities and associations with regional scope. As part of this effort, YAKSHA will build a whole ecosystem of partners around its solutions. This will contribute to enhancing cybersecurity skills in Europe and creating new positions for cybersecurity specialists in ASEAN. Moreover, the direct access to the all-important ASEAN market provided to partners will positively impact the competitiveness of European security industry

Keywords: asean eu cooperation,cybersecurity,data analytics,software development
Computational characterisation of radiosensitising nanoparticles and their properties (Radio-NP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-07-01
End date: 2021-06-30
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

Coated metal nanoparticles (NPs) in molecular environments are widely studied for applications in nanobiotechnology and nanomedicine. Understanding of the nanoscale phenomena (formation and transport of secondary electrons, free radicals and their chemical interactions) induced by NP irradiation with ion beams is crucial for enhancing the potential of novel radiotherapy techniques. The Radio-NP project aims at the atomistic computational analysis of (i) structural properties of coated metal NPs in biological environments and (ii) the impact of these properties on the formation and transport of secondary electrons and radicals in the vicinity of NPs irradiated with ions. The realised approach will combine (i) the ab initio framework to evaluate parameters of quantum transformations of system constituent molecules, (ii) classical molecular dynamics (MD) employed in the advanced scientific software MBN Explorer to characterise NPs and study their interaction with molecular media, and (iii) irradiation-driven MD - the novel and unique implementation in MBN Explorer, to model random interactions of the medium with secondary electrons emitted from the NPs, with account for possible chemical transformations. The recently developed IDMD approach will be applied for the first time to model irradiation-induced chemistry in the vicinity of complex NPs. This methodology will go beyond the physics of the Monte Carlo approach widely used to study nanoscale mechanisms of energy deposition under NP irradiation. The interdisciplinary research program of Radio-NP will be carried out at MBN Research Center - an SME that develops MBN Explorer software. Radio-NP will combine applicant’s knowledge in radiation physics and chemistry with strong expertise of the host in professional software development. The applicant will thus gain a broad set of scientific, technical, complementary and entrepreneurial skills that are highly demanded for his further career as a professional researcher.

Keywords: irradiation induced chemistry,reactive oxygen species,irradiation driven molecular dynamics,computational modelling
How will coral reefs look like in the future? Adaptive mechanisms and sublethal effects in corals under global change (CoralChange)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,United States
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-01-01
End date: 2023-08-31
Duration (months): 36.0
Total project cost (EUR): 245732.16
EU funding (EUR): 245732.16
Participants: 2
Project status: SIGNED

Coral reefs are among the most diverse, spectacular and productive ecosystems on the planet. However, coral reefs are also among the marine ecosystems more susceptible to the adverse effects of the on-going global change. The frequency and severity of coral bleaching and mass mortality events increases every year, with serious consequences on the long-term viability of coral populations. However, during the last years, few studies have investigated the future of coral populations under different global change scenarios using demographic models. Moreover, these studies have not considered the capacity of corals to adjust their physiology to maintain performance despite environmental change (acclimatization) with the additional energetic cost of this adaptive mechanisms and their consequent transgenerational effects on the viability of future offspring. The CoralChange project will investigate, for the first time, the transgenerational effects induced by global change in stony coral and octocoral species in order to determine how their population dynamics and viability is compromised in the long-term. To achieve this goal, I will develop demographic predictive models combining field and experimental data that include coral physiological condition, trophic plasticity, reproductive success and larval viability. This new approach will identify the possible energetic costs of adaptive mechanisms to ocean warming and acidification that may undermine the early, and most vulnerable, life stages of corals. The results of this study will be essential to develop effective management and conservation strategies to safeguard coral reefs under multiple stressors, as well as identify coral species and populations with higher probability to survive in future conditions.

Keywords: global change,coral reefs,coral reproduction,adaptive mechanisms,sublethal effects
Many-body effects in hybrid quantum systems (MEHYB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Austria
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-04-01
End date: 2017-03-31
Duration (months): 24.0
Total project cost (EUR): 166156.8
EU funding (EUR): 166156.8
Participants: 1
Project status: CLOSED

The interdisciplinary field of hybrid quantum systems pursues the integration of different quantum systems from AMO and solid-state physics to harness their combined functionalities in an optimal way. Prominent examples are long-lived spin ensemble quantum memories for superconducting qubits or (opto-)mechanical quantum transducers, which are currently experimentally implemented for future quantum information processing applications. The general aim of this project is to identify and analyze a new and range of applications for hybrid quantum systems for the study of non-equilibrium quantum many-body effects and phase transitions in open quantum systems. For that purpose the hybrid system approach offers many, still unexplored advantages for combining dissipative and coherent elements in a controllable and scalable way. The focus of this project is two-fold: i) We will analyze the implementation of collective spin models in hybrid quantum system arrays consisting of spin ensembles coupled to microwave cavities and show that this system can serve as prototype model for identifying universal features of non-equilibrium phase transitions in open quantum systems. ii) We will study superconducting qubit arrays with integrated nanomechanical resonators for the implementation of spin models coupled to engineered local reservoirs. This will provide a first realistic approach for simulating open many-body quantum systems coupled to unconventional reservoirs, exhibiting, for example, strong site-dependent temperature variations, or mixed positive and negative temperatures. Analyzing these specific models will open a path for hybrid quantum system arrays as a new quantum simulation platform for non-equilibrium and open quantum many-body systems.

Keywords: hybrid quantum systems,cavity qed,nanomechanics,superconducting qubits,nv centers
Innovative technology for Geomechanical and Geophysical Stability Analysis in Tailings Dams (Medusa)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2020-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Tailings dams used in mining to collect waste of production in huge ponds are extremely risky in case of collapse. The failure rates of the 3,500 tailings dams around the world are extremely high: the list of accidents happened in the last 5 years include at least 4 major events per year, killing more than 500 persons and releasing in the environment millions of cubic meters of toxic material. Existing in-situ geotechnical and geophysical testing devices do not provide accurate information about the critical parameters to verify risk of liquefaction of sloping ground, which is the main causing factor responsible for the collapse of dams. Medusa is an innovative geotechnical testing device allowing preventive identification of slope instability and static / seismic liquefaction of tailings dams in a quick, precise, simple and cost-efficient way. Medusa is an automatic, operator-independent and easy to use testing procedure, with exceptional standardization, repeatability and reliability of the test results. Medusa can become the new standard for routine safety tests in tailing dams. Medusa is derived from the Marchetti Dilatometer Test (DMT) produced and sold by Marchetti, which presents limits, intrinsically related to the use of the pneumatic method, which makes it not applicable in tailings dams. Medusa is an evolution of the DMT concept making it usable in tailings dams: electro-mechanical self-contained and cable-less probe, allowing autonomous and automatic procedure eliminating the pneumatic-electric cable. The solution is a TRL6 and will be tested in operational environment (TRL7) in a tailing dam during 2019 thanks to collaboration with first client. The target of the feasibility study is to analyse the outputs of the tests in operational environment and define the product implementation plan, the manufacturing plan, confirm the investment required and prepare an Investor Ready Business Plan to be discussed with potential industrial or financial investors.

Keywords: tailings dams,slope instability and liquefaction,mining,flat plate dilatometer,geomechanical soil analysis,soil parameters investigation,shear wave velocity and stress hystory
Provision of services to enhance the innovation management capacities of SMEs in the East of England - 2014 (EECIPInnoman)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: United Kingdom
Call: INNOSUP (H2020-Adhoc-2014-20, 2014)
Start date: 2014-05-01
End date: 2014-12-31
Duration (months): 8.0
Total project cost (EUR): 38953.75
EU funding (EUR): 31163.0
Participants: 1
Project status: CLOSED

Lack of innovation management capacity is recognised as an important barrier to creating economic impact (competitiveness, growth and jobs) from innovation activities in SMEs. To address this, this action shall provide specialized consulting services addressing innovation management capacity to SMEs in the East of England which possess significant innovation activities. Beneficiaries of the SME instrument shall as well receive support to enhance their innovation management capacity through this action.

Keywords: innovation,horizon2020,sme instrument
Identity matching from still images without face information (StillNoFace)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Greece,United States
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2017-08-31
Duration (months): 24.0
Total project cost (EUR): 168391.8
EU funding (EUR): 168391.8
Participants: 2
Project status: CLOSED

In computer vision, human identity matching from images and/or video has been an active research topic for more than two decades and its popularity is increasing with the increase in computing power. The state of the art techniques are based on face images and gait recognition from long video sequences. However, in many real applications only some static images of the subject may be available where face information is missing (e.g. posterior views). These scenarios have not been addressed by the research community as they are difficult to handle. In this action, we propose a method for matching identities from a set of 2D images of a person without any facial information. The method consists of two steps: at first, the human body is modelled by a 3D articulated model whose pose is estimated by its 2D projections onto the images. Then, biometric features are computed by fitting 3D deformable models to the image data, thus capturing the form and size of the main parts of the anatomy. The overall framework works under a probabilistic framework, with a learning step, in order to encode pose and anatomy variations between a set of individuals that are to be identified.
Investigating Ror2-dependent non-canonical Wnt signaling in bone remodeling (ROR2BONE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-01
End date: 2018-11-02
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

Wnt signaling is composed of the canonical and non-canonical pathways. Canonical Wnt signaling is dependent on β-catenin activation and has become a major focus for targeting osteoblast-mediated bone formation in the context of treating the debilitating disease osteoporosis. However, much less is known about the role of the non-canonical pathway in bone formation. Unpublished data of the host laboratory demonstrates that targeted deletion of the non-canonical Wnt signaling Receptor tyrosine kinase-like orphan receptor 2 (Ror2) in osteoblasts in mice causes a high bone turnover with increased bone formation and enhanced osteoclast-mediated bone resorption. I thus hypothesize that Ror2 regulates bone remodeling by altering signaling in osteoblasts and their interaction with osteoclasts. In Aim I, I will determine cell autonomous effects of Ror2 on osteoblasts by analyzing cell differentiation, proliferation, survival, and by performing functional studies both in vitro and in vivo. Additionally, since osteoblasts provide pro- and anti-differentiation signals to osteoclasts, Aim I will further explore if Ror2 alters the activity of these signals and investigate the resulting phenotypic changes in osteoclast function. In Aim II, I will undertake an in-depth experimental approach combined with an innovative bioinformatics analysis to investigate the osteoblast-specific non-canonical Wnt signaling cascade downstream of Ror2 after reconstituting Ror2-deficient cells with wild type or Ror2 mutants. Lastly, in Aim III I will directly address the therapeutic potential of Ror2 in several in vivo bone turnover models utilizing a chimeric Ror2-Fc soluble receptor. In summary, I will use state of the art in vivo and in vitro approaches to delineate the downstream Ror2 signaling cascade in osteoblasts and its functional effect on bone remodeling. This fellowship is instrumental in catalyzing career opportunities for me as it provides an ideal environment to reach my full potential.

Keywords: ror2,non canonical wnt,osteoblast,osteoporosis,bone anabolic
A high-fidelity isogeometric simulation methodology for fracture in porous media (PoroFrac)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2016-01-01
End date: 2020-12-31
Duration (months): 60.0
Total project cost (EUR): 2329520.0
EU funding (EUR): 2329520.0
Participants: 1
Project status: CLOSED

Fracture in heterogeneous, (partially) fluid-saturated porous media is a multi-scale problem with moving internal boundaries, characterised by a high degree of complexity and uncertainty. Nevertheless, in spite of an abundance of research on fracture in solid materials, there is relatively little work on fluid-saturated porous materials. Herein, a robust, flexible simulation technology will be developed for existing faults and propagating fractures in such media. The project consists of three pillars, each of which will have a scientific impact in its own right, complemented by a horizontal, application-oriented theme, which links the pillars, creates synergy and added value, and applies and elaborates the technology for hydraulic fracturing and for fault dynamics during earthquakes. In pillar 1 a mesoscopic, multi-phase model will be developed for fluid transport in cracks which are embedded in a fluid-saturated porous medium. The development of an adaptive spline technology in pillar 2 will enable to capture crack propagation and branching in arbitrary directions on arbitrary discretisations. The reliability method of pillar 3 will make it possible to make a quantitative assessment of the probability that, in a layered, heterogeneous medium, a crack propagates in a certain direction. Its successful completion will pave the way for a wider acceptance and use of reliability methods in fracture analyses, well beyond the primary application area of porous media. The linking theme will showcase some direct applications, in hydraulic fracturing and in earthquake analysis, but has a much wider range of applicability, e.g. for the safety analysis of CO₂ or nuclear waste storage in sub-surface formations, or fracture in fluid-saturated human tissues. Thus, the project will result in a robust simulation tool for fracture propagation in fluid-saturated porous media with unprecedented predictive capabilities for societal issues in energy, health, environment, and safety.

Keywords: fracture,computational mechanics,porous media
COULD SENESCENCE BE ADAPTIVE? CAUSES AND CONSEQUENCES OF AGING ACROSS THE TREE OF LIFE (WHYAGE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-05-01
End date: 2019-08-28
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

Why do organisms age? This is surely one of the most compelling questions in biology. With advancing age, organisms can see physiological decline leading to higher mortality and lower fertility, a process known as ‘senescence’. The foundations of aging research state senescence should be inevitable in any organism, and is likely a by-product of attenuation in force of selection with age. But is senescence inevitable? Could senescence be adaptive? Senescence is not inevitable, according to recent research from the Max Planck Odense Center, University of Southern Denmark. Species’ aging trajectories are diverse; mortality and fertility may increase, decrease or stay constant with age. We need a new way to understand aging, which recognises this diversity and seeks to understand pattern and process in the evolution of aging across the tree of life. The WHYAGE project explores ecological consequences and evolutionary causes of diversity in aging from this ‘macro’ perspective. Senescence could be adaptive. This proposal presents a theoretical framework under which certain environmental disturbances affecting population age structures could, through population-level processes, favour senescent individuals. More generally, diverse environmental disturbance regimes could help explain diversity of aging across the tree of life. Three objectives facilitate the project. First, demographic method development will allow better understanding of aging trajectories in mortality and fecundity, and population dynamics influenced by these. Second, comparative phylogenetic analyses of global demographic databases of plants and animals will uncover the consequences of aging for population dynamics across the tree of life. This knowledge will inform the third objective; development of theoretical population models exploring how environmental disturbances and population dynamics feed into evolutionary processes, and using these to find conditions under which senescence may be adaptive.

Keywords: aging senescence mathematics statistics model theory population phylogeny evolution comparative database animal plant environment disturbance perturbation dynamics demography transient stochastic