Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Optimizing Vision reHABilition with virtual-reality games in paediatric amblyopia (V-HAB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-03-01
End date: 2024-08-10
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: SIGNED

To reach for a bottle (motor), we need to be able to identify its properties (attention) and know where in space it is located (3-dimensional (3D) vision). This cascade is however impaired in some developmental disorders of vision, like Paediatric Amblyopia (PA) or lazy eye. With this proposal, I first aim to gain insights in the underlying deficits of PA, by combining expertise from the vision sciences, cognition and motor control research fields. These insights will provide a deeper understanding of the core deficits of children with PA, and their inter-relationship. I will put specific emphasis on the study of 3D vision and its impact on selective attention and motor planning, as these have previously been understudied, despite their clear impact on vision and potential coexistence in PA. Second, I aim to test the efficiency of a novel, ethological, and engaging 3D games in a virtual reality environment to improve vision in children with PA. Thirdly, I will examine whether the improvements on vision are accompanied by changes in attention and motor control and which are the underlying brain mechanisms of such improvements. Lastly, by using artificial intelligence approaches on treatment outcome, I will be able to provide guidelines toward a personalized medicine tailored to the patient’s needs. To succeed in this project, I will (i) combine measures of the traditional basic vision tests with novel functional vision evaluation, (ii) quantify uni- and multisensory selective attention with behavioural and brain imaging (electrical neuroimaging) methods, (iii) integrate sensor-based measures of motor planning during reaching, (iv) develop a novel, efficient and ethological virtual reality training to recover 3D vision in children with PA. This project will accumulate clinically relevant results that will be disseminated to the scientific community and communicated to the clinicians and the children’s families through a variety of activities.

Keywords: rehabilitation,virtual reality,motor control
Thermochemical imaging of the Earth’s mantle: Global inversion of seismic waveforms, satellite gravity data and surface elevation (WINTERC-3D)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Ireland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-03-01
End date: 2017-02-28
Duration (months): 24.0
Total project cost (EUR): 187866.0
EU funding (EUR): 187866.0
Participants: 1
Project status: CLOSED

The thermochemical structure of the Earth’s lithosphere and underlying mantle controls fundamental dynamic processes including volcanism, seismic activity and surface topography variations. The growth of very large terrestrial and satellite geophysical data sets over the last few years, together with the advancement of petrological and geophysical modelling techniques, now present an opportunity for global, thermochemical 3D imaging of the lithosphere and upper mantle with unprecedented resolution. Established methods of seismic tomography and gravity data analysis constrain distributions of seismic velocity and density at depth, both depending on temperature and composition of the rocks within the Earth. However, independent modelling and inversion or a simple combination of models based on gravity and seismic data alone suffer from the intrinsic non-uniqueness of each type of models. Thermodynamic links between seismic velocities, density, temperature, pressure and composition within the Earth can now be modelled accurately using new methods of computational petrology. This project combines state-of-the-art seismic waveform tomography (using both surface and body waves), newly available global gravity satellite data (geoid and gravity anomalies and new gradiometric measurements from GOCE mission) and surface elevation within a self-consistent thermodynamic framework. A new method for global thermodynamic tomography will be developed and applied to obtain a robust and, at the same time, detailed thermochemical model of the Earth’s lithosphere and upper mantle.

Keywords: integrated geophysical petrological modelling,lithosphere,upper mantle,mantle composition,geotherm,seismic tomography,gravity,remote sensing,waveforms,gradiometry
Hybrid Fixed Leading Edge (HFLE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Spain,Belgium,Belgium
Call: Automated injection RTM system process based in innovative sensor technologies in a low cost smart manufacturing tooling prototype and any tooling involved in the manufacture or the validation of the structure (H2020-CS2-CFP03-2016-01, 2016)
Start date: 2017-02-01
End date: 2019-12-31
Duration (months): 35.0
Total project cost (EUR): 1316857.5
EU funding (EUR): 999176.63
Participants: 4
Project status: CLOSED

The proposal is adressing the topic JTI-CS2-2016-CFP03-LPA01-14 Automated injection RTM system process based on innovative sensor technologies in a low cost smart manufacturing tooling prototype and any tooling involved in the manufacture or the validation of the structure. The final objective of this topic is to produce the needed tooling to manufacture the HTP Leading edge structure (modified to include a HLFC system) using liquid resin injection processes, in particular RTM process to produce the mentioned part. The resulting structure shall comply with the actual regulation of the aerospace sector, in particular regarding geometrical tolerances and defects. Coexpair is the leader of this project, the other partners are Tecnalia, Pégard Productics and University of Liège. In order to produce the needed tooling to manufacture the HTP Leading edge structure, 5 elementary technology blocs are defined as objectives : 1°) low cost/ natural materials employed in the tooling manufactured, 2°) eco-design for of the tooling manufactured, 3°) energy savings during the manufacture processes of the future parts, 4°) manufacturing processes simplification in order to improve the repetitiveness of the process, 5°) production time savings to reduce the cost and production lead times. A “quick” specimen was manufactured prior to project submission to show the RTM process is suitable for the project. The project focuses on the automation of manufacturing steps of RTM process, including ply cutting and mold cleaning. Elementary tests of a few key points of the automation will be performed in industrial environment (Coexpair shop). In order to optimize floor shop organization, work flow simulation will be performed. In addition to Coexpair experience on RTM process and mold design, the consortium gathers experience in complex part mold machining, experience in robotic development and preforming automation. The project is planned within a duration of 24 months.

Keywords: low cost tooling,titanium cfrp combination
Disentangling the effects of CO2 fertilization, nutrient limitation and water availability on forest ecosystem processes: Estimating their long-term consequences on SW European forests (DENDRONUTRIENT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

European forestry is fast evolving as forests could experience in the near future important changes in climate and also in management, which is moving from timber production to values such as bioenergy, carbon sequestration, biodiversity and others. These factors could change the idoneity of traditional forestry in Scots pine forests (which cover important areas in Europe). The project´s objectives are: 1) To characterize past and estimate future effects of forest management and climate change on carbon and nutrient budgets in Pinus sylvestris stands in SW Europe, to support sustainable forestry that maximizes nutrient and carbon use efficiency and therefore tree growth; 2) To develop, evaluate and apply reliable ecologically-based mathematical models that can be applied in forest management, to study interactions among elevated atmospheric CO2, tree growth and limiting nutrients and moisture. To achieve these objectives the project will be implemented in three stages: 1) Field and archival samples form experimental plots in Scot pine stands in the Pyrenees will be used to analyze connections between soil, leaf and stem nutrient status in the last 16 years. The magnitude of ecosystem biomass and nutrient pools will be estimated to calculate the historical change of nutrient use efficiency by the pines. Historical leaf NUE will be estimated through leaf area scanning combined with chemical analysis. Stem water and nutrient status will be estimated by wood scanning combined with techniques discriminating isotopes of carbon and nitrogen. 2) The ecosystem model FORECAST-Climate will be calibrated, validated, and used as a virtual lab to test the relative importance of nutrient, water, and CO2 availability on tree growth. 3) A battery of climate change (temperature, precipitation and CO2 concentration) and forest management scenarios will be simulated to assess their long-term consequences and provide guidelines on the potential consequences of each management option.

Keywords: forest ecology,dendrochronology,dendrochemistry,nutrient use efficiency,nutrient cycling,carbon budget,ecological modelling,sustainable forest management
Treating mitochondrial disease caused by pathogenic mtDNA mutations (mtDNA-CURE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Germany,Sweden
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2018-01-01
End date: 2023-06-30
Duration (months): 66.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 2
Project status: SIGNED

This proposal describes a series of powerful experimental strategies to develop a completely novel treatment for mtDNA mutation disease based on identifying unknown mechanisms controlling mtDNA replication. Several hundred different mtDNA mutations affect tRNA genes and impair mitochondrial translation leading to human disease. There is typically heteroplasmy with a mixture of wild-type and mutated mtDNA, and the mutations are acting in a “recessive” (loss of function) way. Very high levels of mutated mtDNA are needed to cause disease in affected patients whereas maternal relatives with high, but sub-threshold levels of mutated mtDNA are completely healthy. The corollary of these observations is that even a small increase of wild-type mtDNA may efficiently counteract disease in affected patients. This hypothesis will be validated by a series of genetic experiments with mice harbouring single pathogenic mtDNA mutations. Furthermore, novel factors controlling mtDNA replication will be identified. In particular, we will elucidate the formation and function of the mammalian displacement (D) loop, which provides a switch between abortive and genome length mtDNA replication. This very fundamental problem in mammalian mitochondrial biology has remained unsolved for decades, but I feel that the innovative experimental strategies I present in this proposal are very powerful and should have a fair chance of being successful. In any circumstance, the project will provide important molecular insights into novel mechanisms relevant for mammalian mtDNA replication. Over the years I have been strongly convinced that congruent results from in vivo and in vitro studies are needed to obtain reliable mechanistic insights and this project is therefore based on the close integration of biochemistry, advanced proteomics and state-of-the-art mouse and fly genetics. Finally, I describe a powerful large-scale screening approach to develop small molecular stimulators of mtDNA replication.

Keywords: mitochondria,mtdna mutation disease,mtdna replication
Preventing Radicalisation Online through the Proliferation of Harmonised ToolkitS (PROPHETS)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Fight crime, illegal trafficking and terrorism, including understanding and tackling terrorist ideas and beliefs
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Spain,Germany,Estonia,Italy,Bulgaria,Croatia,Belgium,Greece,Greece,Netherlands,United Kingdom,United Kingdom
Call: Human Factor for the Prevention, Investigation, and Mitigation of criminal and terrorist acts (H2020-SEC-2016-2017-2, 2017)
Start date: 2018-05-01
End date: 2021-06-30
Duration (months): 38.0
Total project cost (EUR): 2998331.25
EU funding (EUR): 2998331.25
Participants: 15
Project status: CLOSED

PROPHETS will look at redefining new methods to prevent, investigate and mitigate cybercriminal behaviours through the development of a coherent, EU-wide, adaptive SECURITY MODEL, built upon the interplay of the human factors within the new cyber ecosystem and capable of addressing the four fundamental dimensions at the core of the phenomenon: 1. early identification of security threats; 2. investigations within a new public-private governance; 3. Increased complexity of the response due to the expansion of the security perimeter towards new societal fields and the emergence of challenging jurisdictional problems; and, last but not least, 4. perception of security and freedoms among citizens, which requires a new communication strategy for LEAs and security policy makers.

Keywords: cybercrime,radicalization,open source intelligence
Parental BONDing for a better start in life (BOND)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Netherlands
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2018-12-01
End date: 2021-05-31
Duration (months): 30.0
Total project cost (EUR): 3420625.0
EU funding (EUR): 2394437.0
Participants: 1
Project status: CLOSED

Annually, 130.000 babies in the EU are born extremely premature, ranging from 24 to 32 weeks of gestation (so called preterms). Currently the vital signs of these pre-terms are monitored with an adhesive electrode system that was originally designed for adults. These electrodes cause stress and pain for the pre-term during the daily removal by which skin damage can occur. Furthermore, the system prevents skin-to-skin contact with the pre-term parents (Kangaroo Mother Care) due to the wires. Stress, pain and impaired Kangaroo Mother Care prevent pre-term development. Research shows that one out of two pre-terms develops concentration disorders and/or cognitive impairments during their lifetime. This results in high healthcare costs. Therefore, neonatologists demand an better solution that allows them to better assess pre-term wellbeing. Bambi Medical, a rising med-tech company, responds to this market need with the introduction of the Bambi Belt. The Bambi Belt is an innovative wireless and non-invasive system that can measure the vital signs of pre-terms. With the Bambi Belt sensors are kept in place via an elastic belt that does not harm the fragile pre-term skin. In addition, the system is wireless and therefore parents are enabled to give significant more Kangaroo Mother Care. This will improve the development of the pre-term and reduce both short-term (less hospital days) and long-term (less costs due to development delays) healthcare costs. These benefits of the Bambi Belt result in a higher quality of care and a more cost-effective solution.

Keywords: pre terms,vital sign monitoring,mother kangaroo care,obstetrics,gynecology
Democratic governance in a turbulent age (Governance)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: ERA-NET Cofund
Partnership: Governance (ERA-NET)
Countries involved: Germany,Estonia,Iceland,Austria,Spain,Ireland,Norway,Belgium,Finland,Lithuania,Poland,Slovenia,Sweden,Switzerland,France,Czechia,Netherlands,Denmark,Luxembourg,Portugal,United Kingdom
Call: ERA-Net Co-fund - Renegotiating democratic governance in times of disruptions (H2020-SC6-GOVERNANCE-2018, 2018)
Start date: 2018-12-01
End date: 2024-05-31
Duration (months): 66.0
Total project cost (EUR): 9090927.0
EU funding (EUR): 3000000.0
Participants: 24
Project status: SIGNED

Democratic politics and governance in Europe are facing turbulent times. This not only affects the institutions of government, but the wider structures and processes that make democratic societies work. In order to respond to them, we require an understanding of the nature, causes and consequences of these challenges, as well as assessments of how governments, political parties, interest groups and other societal actors can effectively address them. With this proposal for a research programme on the topic of governance, NORFACE offers a timely investigation of the precise nature of the turbulence, but also how European states can negotiate it and develop strategies to enhance the quality of democratic politics and governance. The proposed programme will focus on themes derived from five critical challenges to democratic governance and the responses to them: inequality and redistribution, the evolving politics of threat, democratisation of information, shifting identities and representation, and the changing authority of institutions. Through collaborative cross-disciplinary research based on cross-national, historical and/or longitudinal comparison, the programme will develop theoretically ambitious and empirically founded insights to enrich the knowledge base upon which to build new institutions, policies and practices and reshape existing ones for a reflective, inclusive and innovative society. NORFACE (New Opportunities for Research Funding Agency Cooperation in Europe) is a collaborative partnership of national research funding agencies in the area of social and behavioural sciences. Since 2004, NORFACE has been committed to leading and developing opportunities for social scientists in Europe by developing thematic joint research programmes; building capacity for transnational and interdisciplinary research; advocating for the societal value of the social sciences; and sharing excellence in research management practices and procedures.

Keywords: government,democracy,europe,inequality,identity,authority,communication,political change
AERIAL COgnitive integrated multi-task Robotic system with Extended operation range and safety (AERIAL-CORE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Spain,Spain,Spain,Spain,Switzerland,Switzerland,Greece,Croatia,France,France,France,Czechia,Netherlands,Denmark
Call: Robotics Core Technology (H2020-ICT-2019-2, 2019)
Start date: 2019-12-01
End date: 2023-11-30
Duration (months): 48.0
Total project cost (EUR): 8595306.25
EU funding (EUR): 8595306.25
Participants: 19
Project status: SIGNED

The main objective of AERIAL-CORE is the development of core technology modules and an integrated aerial cognitive robotic system that will have unprecedented capabilities on the operational range and safety in the interaction with people, or Aerial Co-Workers (ACW), for applications such as the inspection and maintenance of large infrastructures. The project will integrate aerial robots with different characteristics to meet the requirements of: (1) Long range (several kilometres) and local very accurate (subcentimetre) inspection of the infrastructure capability; (2) Maintenance activities based on aerial manipulation involving force interactions; and (3) Aerial co-working safely and efficiently helping human workers in inspection and maintenance. AERIAL-CORE technology modules will be based on Cognitive Mechatronics and apply cognitive capabilities to aerial morphing in order to combine long range endurance and hovering for local observations, manipulation involving force interactions, and co-working with humans. The project will develop: (1) Cognitive functionalities for aerial robots including perception based on novel sensors, such as event cameras, and data fusion techniques, learning, reactivity, fast on-line planning, and teaming; (2) Aerial platforms with morphing capabilities, to save energy in long range flights and perform a very accurate inspection; (3) Cognitive aerial manipulation capabilities, including manipulation while flying, while holding with one limb, and while hanging or perching to improve accuracy and develop greater forces; (4) Cognitive safe aerial robotic co-workers capable of physical interaction with people; and (5) Integrated aerial robotic system for the inspection and maintenance of large infrastructures. The system will be demonstrated in electrical power system inspection and maintenance, which is an application with a huge economic impact that also has implications in the safety of workers and in wildlife conservation.

Keywords: aerial robotics,robotics core technology