Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Active and Driven Systems: Nonequilibrium Statistical Physics (ADSNeSP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-10-01
End date: 2023-09-30
Duration (months): 72.0
Total project cost (EUR): 2043630.0
EU funding (EUR): 2043630.0
Participants: 1
Project status: SIGNED

Active Matter systems, such as self-propelled colloids, violate time-reversal symmetry by producing entropy locally, typically converting fuel into mechanical motion at the particle scale. Other driven systems instead produce entropy because of global forcing by external fields, or boundary conditions that impose macroscopic fluxes (such as the momentum flux across a fluid sheared between moving parallel walls). Nonequilibrium statistical physics (NeSP) is the basic toolbox for both classes of system. In recent years, much progress in NeSP has stemmed from bottom-up work on driven systems. This has provided a number of exactly solved benchmark models, and extended approximation techniques to address driven non-ergodic systems, such as sheared glasses. Meanwhile, work on fluctuation theorems and stochastic thermodynamics have created profound, model-independent insights into dynamics far from equilibrium. More recently, the field of Active Matter has moved forward rapidly, leaving in its wake a series of generic and profound NeSP questions that now need answers: When is time-reversal symmetry, broken at the microscale, restored by coarse-graining? If it is restored, is an effective thermodynamic description is possible? How different is an active system's behaviour from a globally forced one? ADSNeSP aims to distil from recent Active Matter research such fundamental questions; answer them first in the context of specific models and second in more general terms; and then, using the tools and insights gained, shed new light on longstanding problems in the wider class of driven systems. I believe these new tools and insights will be substantial, because local activity takes systems far from equilibrium in a conceptually distinct direction from most types of global driving. By focusing on general principles and on simple models of activity, I seek to create a new vantage point that can inform, and potentially transform, wider areas of statistical physics.
Supporting Active Ageing through Multimodal coaching (SAAM)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: Research and Innovation actions
Countries involved: Austria,Austria,Germany,Bulgaria,Slovenia,United Kingdom
Call: Personalised coaching for well-being and care of people as they age (H2020-SC1-2017-CNECT-1, 2017)
Start date: 2017-10-01
End date: 2021-05-31
Duration (months): 44.0
Total project cost (EUR): 3996400.0
EU funding (EUR): 3996400.0
Participants: 10
Project status: CLOSED

As in the rest of the world, Europe faces an on-going crisis in caring for its aging population. Citizens are living much longer than ever before, with increasingly complex medical, social, and infrastructural needs, but most EU social support services and structures are lagging very much behind the growing need. While many efforts have focused on better access to healthcare and the expansion of assisted and social care housing, one of the main intervention points, enabling the aging population to remain in their homes longer, is just now becoming a primary developmental priority. Caring for the aging population as they transition from active and independent lifestyles to those requiring significant external support is a large and complex field, with many approaches to the great diversity of citizen need profiles. Within the SAAM project (Supporting Active Aging through Multimodal coaching) we focus upon innovative, technology-enabled approaches to support the aging population living at home, with a novel and practical emphasis on ambient sensing and learning of user needs and preferences, and effective coaching by leveraging the user’s social support networks. Over three years, the project’s partners will develop and test new methods allowing Europe’s aging population to remain active, independent and longer in their homes.

Keywords: ambient sensing,social coaching,ambient support systems,active ageing
Bio-based FERtilising products as the best practice for agricultural management SusTainability (B-FERST)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Public-private partnerships
Destination: Bio-based Industries
Action type: Innovation actions
Partnership: BBI (Art-187)
Countries involved: Italy,Spain,Spain,Spain,Italy,Germany,Spain,Belgium,Poland,North Macedonia,Belgium,Slovenia
Call: Produce biopesticides or bio-based fertilisers as components of sustainable agricultural management plans (1) (H2020-BBI-JTI-2018, 2018)
Start date: 2019-05-01
End date: 2024-10-31
Duration (months): 66.0
Total project cost (EUR): 10016296.0
EU funding (EUR): 6787075.75
Participants: 18
Project status: SIGNED

B-FERST’s main objective is to integrate the valorisation of bio-wastes in agriculture management plans creating anew circular and bio-based value chains considering a bilateral interaction between farming and fertiliser sectors focused on a paradigm shift in the fertiliser value chain with 8 specialised fertilisers. Specialised nutrient mixes are required to achieve a more sustainable management of resources by tailor-made nutrient dosing adapted to farmer systems. The SUSTAINABILITY of B-FERST is based on the reuse of bio-waste to replace non-renewable, non-domestic and energy intensive raw materials: 1) Bio-based solid fertilisers including renewable sources of macronutrients (N,P,K) obtained from 3 by-products streams: i) ashes, as source of P & K from: Waste Water Treatment Plants (WWTP) (sewage sludges), & agri-food such as: slaughterhouse waste, olive & livestock wastes; ii) struvite as source of P & N from WWTP & agro waste (pig slurries), and; iii) compost as source of organic carbon compound, N, P & K from Organic Fraction of Municipal Solid Waste) OFMSW, WWTP & agro waste (manure -livestock-). 2) Biostimulants for soil nutrient improvement from two approaches: selected microbiological strains as Microbial Plant Biostimulant (MPB) or Non-Microbial Plant Biostimulant (NMPB) from cardoon oil meal processing (agricultural by-products) and compost extracts. Bio-degradable coatings based on biopolymers will be used when MPB is added to the fertiliser products to protect the beneficial microorganisms and guaranty their performance. The VIABILITY is based on previous R&D from other RIA projects. The manufacturing process will be demonstrated at a demonstrative industrial scale. Then specialised fertilisers will be performed and validated in 5 crops tests (Spain, Italy, France, Poland and Ukraine) comparing their functionality to that of traditional fertilisers in terms of: sustainable sourcing, logistics, soil and growing conditions, reaching a TRL6

Keywords: bio based fertilisers,biostimulant,nutrients,soil conditioning,industrial upscaling,bio based value chain,sustainability,logistics,business plan
An integrated hypothesis for cognitive and positive symptoms in schizophrenia (INTEGRATE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Norway
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-12-01
End date: 2021-12-01
Duration (months): 24.0
Total project cost (EUR): 208400.4
EU funding (EUR): 208400.4
Participants: 1
Project status: CLOSED

An integrated hypothesis for cognitive and positive symptoms in schizophrenia: Schizophrenia is a complex developmental brain disorder with three main clusters of symptoms: (i) positive (psychosis, delusions and hallucinations), (ii) negative (reduced motivation and social withdrawal), and (iii) cognitive (memory and executive function deficits). For the last 50 years, the only effective treatment has consisted of antipsychotics targeting dopamine receptors. Yet, antipsychotics control mostly the positive symptoms and are largely ineffective at treating other deficits. It is frequently assumed that distinct pathophysiological mechanisms underlie different symptoms. Psychosis is associated with striatal hyperdopaminergia, probably due to abnormal activity of midbrain dopaminergic neurons. Yet cognitive deficits seem to arise from cortical excitation/inhibition unbalance. I propose to test, in a mice model, the hypothesis that striatal hyperdopaminergia results from dysfunctional cortical inhibition. If verified, this would suggest that normalizing cortical activity in schizophrenia might both restore cognitive function and prevent psychosis.

Keywords: erbb4 schizophrenia interneuron frontal cortex striatum dopamine e,i balance pet optogenetics animal model transgenic midbrain substantia nigra electrophysiology in vivo neurodevelopment
Critique and Reformation of Doctrine in International Investment Law: Legal Theory and Empirical Legal Studies (CReDItIs)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-09-01
End date: 2024-03-30
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: CLOSED

The protection of international investments by international agreements such as the Transatlantic Trade and Investment Partnership and its enforcement by Investor-State Dispute Settlement is currently subject of an important political debate. That debate pits the goal of attracting and protecting international investments against that of avoiding the exploitation of host countries and undermining their domestic law. CReDItIs will develop a new theoretical foundation for international investment law, putting particular emphasis on systematic and theoretical rigour and using expropriation as a case-study. It challenges the dominant stance of legal scholarship by using both legal theory and legal-empirical research. For orthodox scholars, the law in international treaties is authoritatively defined by what 'authorities' have said. Ad hoc investment tribunals adjudicate on investment disputes on the basis of mostly bilateral investment agreements. These awards do not have formal precedential value, and the agreements they rely upon are similar, but not identical. Yet not only are awards of great factual importance, legal scholarship believes that they can somehow be applied even to treaties on which they do not adjudicate. In contrast, for legal-realist empiricism, the law is what the courts decide. CReDItIs will contrast these views with the Pure Theory of Law, which is a legal theory arguing that seeing law as norms is possible without admixing it with nonlegal norms, or reducing law to facts. It will highlight the factual importance of awards and treaties through the use of empirical tools such as citation network analysis while distinguishing this from false designs to unify and concretise these results as law. The law remains fragmented; the law remains unspecific, even if and when judicial pronouncements and treaties are similarly worded.

Keywords: international investment law and arbitration,general public international law,legal theory,theory of legal,scholarship,jurisprudence
From Skin to Skeleton: Revolutionary Contactless and Non-Ionizing 3D Digital Diagnosis and Monitoring of Spinal Disorders in Adolescents (ScolioSIM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 191149.44
EU funding (EUR): 191149.44
Participants: 1
Project status: CLOSED

Scoliosis is a 3D musculoskeletal disorder of the spine that affects the quality of life and physical ability of patients. Almost 80% of all cases comprise of adolescent idiopathic scoliosis (AIS) with an estimated prevalence of 36 million new patients worldwide by 2050. The drawback of current diagnostic methods in AIS assessment is their harmful effect, especially due to the multiple radiographic exposures required for monitoring disease progression. A new generation of optical techniques for estimating curvature of the spine and evaluating deformity-related changes from a 3D digitalized surface of the patient’s back are considered as an alternative to ionizing methods. However, none of these non-ionizing approaches have been applied to calculate the internal parameters of AIS and neglect the 3D complexity of the internal spinal structure. The proposed action aims to test and improve a markerless computer-aided optical solution (ScolioSIM1.0) that can generate a 3D model of the patient-specific scoliotic spine, and to reliably predict internal and external biomechanical characteristics and parameters of AIS without exposing patients to ionizing radiation. This process includes the development of a novel computational algorithm for online monitoring of AIS after treatment and regular follow-ups (ScolioSIM2.0) and its integration into the first multi-modular web-based platform (ScolioMedIS). The fellowship involves an experienced candidate, Dr Saša Ćuković, from UniKg, Serbia to conduct this multidisciplinary and innovative project at ETH Zurich in the group of Prof. Dr William R. Taylor. The action also provides opportunities for two-way knowledge transfer in the field of musculoskeletal modelling, computational biomechanics and new ICT methods thus, presenting a clear target for the fellow to reach professional independence through research and intense training, and for the host to broaden research domains specifically in the field of spinal disorder biomechanics.

Keywords: adolescent idiopathic scoliosis,non invasive 3d digital diagnosis,patient specific 3d models,spine,scoliosis monitoring,computational model,spinal biomechanics
Estonian Researchers' Nights 2014-2015 (RNEst14-15)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Estonia,Estonia
Call: European Researchers' Night (NIGHT) (H2020-MSCA-NIGHT-2014, 2014)
Start date: 2014-06-01
End date: 2015-11-30
Duration (months): 18.0
Total project cost (EUR): 164375.0
EU funding (EUR): 152500.0
Participants: 3
Project status: CLOSED

The main aim of the Estonian Researchers’ Nights 2014-2015 (RNEst14-15) is the highlighting of the accomplishments of Estonian researchers and scientists with special focus on their achievements in the field of medicine and other areas influencing the well-being and health of the citizens of Estonia and Europe. The focus of the events of RNEst14-15 will be on different themes of the healthcare spectrum- in 2014, the Estonian Researchers’ Night will be dealing with the concepts of illness prevention (including sports, healthy lifestyles and the diagnostics of potential illnesses), while in 2015 the focus will shift to the issues of treatment, care and the future of medicine in the country. During the events of RNEst14-15, the science and scientists behind the technologies, methods and schools of thought inluencing the health of the Estonian (and European) population will be explored and, to stress the importance of collaborative experiences of the pan-European Researchers’ Night and to broaden the horizon of the topics dealt with, joint events will take place in cooperation with other Researchers’ Night organizers from across Europe (to a greater extent with the organizers from Finland but also with organizers from Belgium, Cyprus, Denmark, Hungary, Ireland, Latvia, Malta, Spain, Turkey, and the United Kingdom) and a special programme will be offered in 2015 to celebrate the 10th anniversary of the European Researchers’ Night.

Keywords: researchers night in estonia,medical sciences,healthcare and well being,science achievements in everyday life
Numbers in the brain: the impact of brain lateralization on numerical abilities (NUMELAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-06-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 2
Project status: CLOSED

Understanding the neural correlates of number cognition is of both intellectual and societal importance: number cognition gives fundamental insight into the evolution of cognitive processes and poor numeracy limits life chances and is a substantial cost to nations. However, the neurological basis of number processing is poorly understood. Furthermore, despite brain lateralization being associated with dyscalculia, an arithmetic learning disorder, the exact impact of brain lateralization on numerical skills is unknown. NUMELAT aims to investigate the neural circuits underlying numerical competence and how these are affected by brain lateralization using zebrafish as a model system. Zebrafish are indeed able to assess numerical magnitude, show lateralized behaviours and it is possible to image neural activity in vivo in behaving larvae. The project will: 1) test whether laterality affects the development and extent of number cognition by: (i) determining the impact of laterality on zebrafish’ ability to assess numerical magnitude. The effect of brain lateralization will be determined by comparing the performance in wild-type and laterality mutant lines. (ii) determining the impact of laterality on developmental trajectories of numerical abilities in wild-type and laterality mutant larvae. 2) Identify neural circuits involved in number processing in wild-type and mutant lines using in-vivo neuroimaging in larvae while assessing numerosity. The use of a species whose genome is sequenced and whose nervous system has been extensively studied will introduce the zebrafish as a model for the study of neurobiology of numbers, with particular regard to the cognitive dysfunctions related to brain lateralization, such as dyscalculia. By combining behavioural analysis and in vivo imaging, NUMELAT provides an innovative approach to study numerical cognition and to address the challenging question about the link between anatomical, functional and behavioural asymmetries.

Keywords: numerical cognition
End-to-End Approach for Mobility-as-a-Service tools, business models, enabling framework and evidence for European seamless mobility (MaaS4EU)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Greece,Hungary,Greece,Finland,Belgium,Netherlands,United Kingdom,United Kingdom,Luxembourg,United Kingdom,United Kingdom,United Kingdom
Call: Innovative concepts, systems and services towards 'mobility as a service' (H2020-MG-2016-Two-Stages, 2016)
Start date: 2017-06-01
End date: 2020-10-31
Duration (months): 41.0
Total project cost (EUR): 3696346.75
EU funding (EUR): 3660256.25
Participants: 18
Project status: CLOSED

With the projected growth in transport demand, the current modus operandi in transport supply is deemed unsustainable and generates the need for innovative services that could support seamless mobility and a shift from car-ownership to usership. An emerging trend towards this direction is the integration of on-demand modes in conjunction with public transport, leading to the Mobility-as-a-Service (MaaS) concept. MaaS is a user-centric, intelligent mobility distribution model, in which users' needs are met via a single platform and are offered by a service provider, the mobility operator. Although activities in this field are ongoing, at present there are no established frameworks and quantifiable evidence about MaaS costs and benefits, users’ needs, as well as its influence on travel patterns and car ownership of various user groups. Against this background the main goal of MaaS4EU is to provide quantifiable evidence, frameworks and tools, to remove the barriers and enable a cooperative and interconnected EU single transport market for the MaaS concept, by addressing challenges at 4 levels, (1) business, (2) end-users, (3) technology and (4) policy. This will be achieved by defining sustainable business models that support the cooperation across transport stakeholders, understanding user needs and choices, implementing the required technological infrastructure (a MaaS mobility hub) and identifying the enabling policy and regulatory frameworks. The project will provide quantifiable evidence about MaaS costs and benefits in 3 real-life, complementary pilot cases, demonstrating the concept in urban, intercity and cross-border trips at 3 EU areas (UK, LUX-DE, HU) The consortium disposes all necessary competences and has been formed to be able to handle all tasks involved in the project, consisting of 17 partners from 9 countries, among them leading industries, renowned research institutions, transport authorities and operators, consultants and one ministry of transport.

Keywords: maas,business models,platform,open data,policies,framework,mobility service integration,cost benefit evidence