Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Inside Speakers' Corner. Late Medieval Italian Anchoresses in European Context. (InSpeCo)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-12
End date: 2019-09-11
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Voluntary reclusion was an ancient form of penitential religious life based on withdrawing into a tight space, either temporarily or forever. The particular phenomenon of urban reclusion which flourished in the 13th and 14th centuries was a mainly female activity, need not be tied to a religious order, and seems to have been linked to the expansion of cities across Europe. It is an important indicator of female levels of religious participation and of their social role since these women often acted as consultants and advisors to the wider community. This research project will thus improve our understanding of a phenomenon that characterized all of Latin Europe, as of the condition of medieval woman, while also reshaping our image of the medieval city, to one scattered with cells. There is, currently, a great disparity in historiographical terms between Italy and the rest of the continent on this subject. Whereas some parts of Europe and of northern Italy are relatively well researched, others are devoid of studies. The aim of this project is thus to verify whether – and if so, how and why – there was an Italian model of reclusion with characteristics different to those beyond the Alps; how recluses related to the urban communities from which they withdrew and the extent to which this phenomenon was a way for medieval women to break the silence imposed by St Paul ("Women are to be silent in the churches. They are not permitted to speak",1 Corinthians 14:34); to exercise from and thanks to the cell a sort of power on the civil and ecclesiastical society; to break out of conventional, restricted roles of mother or wife or nun imposed by the medieval society, or more often a dignified way of life for poor single women, for whom the lack of a dowry barred entry to a nunnery or marriage. The first step will thus be the construction of a prosopographical database of Italian anchoresses mapping the phenomenon, followed by a comparative study of Italy in European context

Keywords: anchoresses,middle ages,voluntary reclusion,medieval religious and social,history,gender studies,inclusion,exclusion,identity,alterity,european identity,sacred,topography,digital humanities
Euro-BioImaging Preparatory Phase II - Project (EuBI PPII)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Coordination and support actions
Countries involved: Israel,Spain,Spain,Spain,Italy,Germany,Norway,Belgium,Finland,Bulgaria,Poland,Slovakia,France,Czechia,Czechia,Netherlands,Netherlands,United Kingdom,Portugal,United Kingdom,Portugal
Call: Preparatory Phase of ESFRI projects (H2020-INFRADEV-1-2015-2, 2015)
Start date: 2016-01-01
End date: 2018-12-31
Duration (months): 36.0
Total project cost (EUR): 1497910.0
EU funding (EUR): 1497910.0
Participants: 22
Project status: CLOSED

Euro-BioImaging (EuBI) is the pan-European research infrastructure project for imaging technologies in biological and medical sciences and has been on the ESFRI Roadmap since 2008. In close match with the scope and objectives of the INFRADEV2 call, Preparatory Phase II (PPII) funding will enable EuBI: • to finalize the submission and approval procedure of its ERIC statutes with the EC and bring them to signature by the EuBI Member States and EMBL to launch the EuBI-ERIC; • obtain commitments for the sustainable funding for the EuBI-ERIC by its Member States; • implement the operational EuBI Hub and recruit its staff to provide user access and services; • define and sign the service level agreements between EuBI-ERIC and the 1st generation of EuBI Nodes; • establish a procedure to increase EuBI-ERIC membership, so that new countries can continuously join the EuBI-ERIC with clear national benefits and contributions. From Dec 2010 until May 2014, EuBI successfully completed its EU FP7-funded Preparatory Phase I, which addressed key technical and strategic questions and provided a blueprint for infrastructure implementation. 14 European countries (BE, BG, CZ, FI, FR, IL, IT, NO, PL, PT, SK, ES, NL, UK), and the PPI coordinator EMBL have signed the EuBI Memorandum of Understanding to jointly undertake the remaining steps required to draft and submit the EuBI ERIC application to the EC. The MoU signatories constitute the EuBI Interim Board (IB), which now governs the Interim Phase. To maintain the successful momentum of Member State engagement, the EuBI PPII project consortium comprises and is fully supported by all IB Members. We have jointly defined clear and measurable objectives that will bring EuBI to full maturity in order to start operation and provide its services to European researchers immediately upon launch of the EuBI-ERIC. The award of PPII funding would leapfrog the start of EuBI-ERIC user access and service provision by at least 1,5 year’s time or more.

Keywords: launch of eubi eric,eubi preparatory phase ii,operational eubi hub and nodes,advanced training in imaging,eubi web access portal,eubi image data services,broadening of eubi membership
In situ stem cell monitoring system based on conductive nanoneedle devices for tracking cell fates in invasive manner (ELECTRO NEEDLE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-10-01
End date: 2020-09-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Stem cell-based therapies to cure nerve system disorders using the self-renewal and multilineage differentiation capacities of the transplanted stem cells have been drawing attention during the past decade. Especially, differentiation of mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) into neural cells are especially investigated since early 2000’s, thanks to their being much less prone to the ethical issues and the risk of developing teratoma. However, the critical challenges are the difficulty in: (i) guiding their proper differentiation to neural cells, and (ii) tracking their fate, distribution, and migration due to the limited tracking methods. In 2015, the Stevens Group at Imperial College London (ICL) developed high-aspect ratio, porous silicon nanoneedles (pSi nNs) for in vitro and in vivo manipulation of cell behaviour. Remarkably, the nNs penetrate the cell membrane but do not damage the nucleus, instead stimulating nuclear condensation (Published in Nat. Mater., ACS Nano, etc.). However, current nNs in the Stevens Group is degradable within 48 hrs which is not ideal for long-term biological studies, especially for detecting/monitoring the cell differentiation during the culture. Recently, the applicant (Dr Hyejeong Seong) newly developed non-porous, solid version of nNs after her joining to the Stevens Group in March 2017. The new nNs exhibited a high stability in cell culture media and buffer solutions, proving their suitability for long-term investigation of cell fate. This provides an ideal framework for manipulating and exploiting cell behaviour for longer periods as a means for understanding differentiation capacity of this promising stem cell source. Furthermore, we’re expecting that the new nNs are modifiable as conductive electronic sensors, byintegrating new nNs with non-cytotoxic electronic devices. Through these devices, cell morphologies and endogenous receptors, will be assayed without invasive immunoassay.

Keywords: non invasive,non toxic,in situ,and reliable monitoring of stem cells using novel nanostructures to ensure the safe and reliable use of differentiated cells in the field of regenerative medicine
Smell Healthcare Technology to Enable Digital Smell Training (SmellHealth)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: United Kingdom
Call: Call for proposals for ERC Proof of Concept Grant (ERC-2020-PoC, 2020)
Start date: 2021-06-01
End date: 2022-11-30
Duration (months): 18.0
Total project cost (EUR): 214285.71
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The aim of this ERC PoC is to enable the design of new digital smell healthcare applications (e.g. smell training) through the development of a highly accurate, efficient, adaptive, and affordable smell-delivery technology (hardware and software components), and demonstrate its use to healthcare professionals. The human sense of smell is powerful, it makes an important and yet often undervalued contribution to our life and wellbeing with a unique link to emotions and memories. Smell dysfunctions or loss (even temporary) give rise to a range of problems, which can affect personal safety, enjoyment of food, personal hygiene, and can cause serious mental health disorders, including depression, anxiety and social isolation. In Europe and the USA, around 20% of the general adult population has some form of smell dysfunction and this number rises to 75% for people aged between 70–80 years. In 2050, 1 in 6 people in the world will be aged 65 years and over. The negative effects of smell dysfunctions have recently been experienced by a larger global population due to the impact of COVID-19. Regardless of a temporary or chronic smell dysfunction, there is an unmet need for digital smell care applications that empower individuals and healthcare professionals to properly care and treat negative effects. Smell training can make a difference to people’s health, personal and emotional wellbeing in older age. Additionally, reliably recording a person’s smell capabilities can detect dysfunctions that can be an early sign of degenerative conditions (Dementia, Alzheimer's and Parkinson's disease), even a decade or more before the onset of cognitive or motor symptoms. SmellHealth will not only provide technological innovation for smell delivery and control, but also enable the collection of reliable data, the creation of digital datasets based on smell performance and thus extend the benefits of personalised electronic healthcare records for monitoring, diagnosis, and prevention.

Keywords: smell delivery technology,smell health applications,digital smell training,human computer interaction,user centred design
Microseismicity Illuminates Subduction Zone Processes (MILESTONE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Czechia
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-06-01
End date: 2026-05-31
Duration (months): 60.0
Total project cost (EUR): 1311480.0
EU funding (EUR): 1311480.0
Participants: 1
Project status: SIGNED

Background microseismicity in subduction zones contains important information on the geometry, kinematics and dynamics of subduction systems. Low-magnitude earthquakes on the plate interface can outline highly locked asperities and thus define the locus of potential future large earthquakes. Rates of aseismic processes like creep or slow slip can be estimated using swarm-like seismicity and/or repeating events, thus complementing geodetic approaches. At depths beyond the megathrust, microseismicity can give important clues to the distribution and motion of fluids, ongoing mineral reactions, as well as the thermal and rheological structure of the downgoing slab. In this project, I propose to use existing large seismic data sets from four subduction zone settings to systematically harvest microseismicity at an unprecedented scale through the use of an innovative automated approach that combines new machine learning approaches into a comprehensive earthquake detection and location framework. This effort will yield consistently picked and located microearthquake catalogs of superior event numbers and spatial resolution, which will be the base for several research avenues with the following outcomes: - high-resolution seismicity catalogs and new 3D plate interface and slab surface geometry models - a new generation of plate interface locking models from combining permanent GPS data inversion with seismicity constraints - highly resolved regional-scale tomographic images of subduction zones - new models of petrology, phase changes and thermal structure across several downgoing plates - a framework for the comparison of seismicity features between different subduction zones The results from the proposed project will be a big leap towards understanding the physics of subduction zone earthquakes as well as deep fluid circulation and mineral phase changes in downgoing lithosphere. They will also serve as valuable input for future models of earthquake and tsunami hazard.

Keywords: subduction zone processes,slab earthquakes,plate interface
Affordable Quantum Communication for Everyone: Revolutionizing the Quantum Ecosystem from Fabrication to Application (UNIQORN)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Tackling grand interdisciplinary science and technology challenges
Action type: Research and Innovation actions
Countries involved: Austria,Austria,Germany,Italy,Germany,Italy,Israel,Germany,Italy,Greece,Belgium,Greece,Netherlands,Denmark,United Kingdom
Call: FET Flagship on Quantum Technologies (H2020-FETFLAG-2018-03, 2018)
Start date: 2018-10-01
End date: 2022-06-30
Duration (months): 45.0
Total project cost (EUR): 9979905.0
EU funding (EUR): 9979905.0
Participants: 17
Project status: SIGNED

Quantum communication is recognised as one of the pillars for the second quantum revolution thanks to its unique potential for information-theoretical data security. Turning this promise into tangible assets depends however, on the availability of high-performance, compact and cost-effective modules for practical implementations. UNIQORN is a well-orchestrated design and manufacturing framework aiming to advance the quantum communication technology for DV and CV systems by carefully laying out each element along the development chain from fabrication to application. Component-wise, UNIQORN will leverage the monolithic integration potential of InP platform, the flexibility of polymer platform and low-cost assembly techniques to develop quantum system-on-chip modules in a cheap, scalable and reproducible way. UNIQORN will deliver bright (10M pairs/s/mW/THz) heralded, entangled and squeezed light sources with 70-fold size reduction and almost 90% cost savings, room-temperature arrayed SPADs and a 10-GHz CV receiver with low-noise TIAs. Fully functional systems based on these assets will include: (i) a network adapter card with integrated real-time QRNG engine, (ii) the first DPS transmitter as pluggable SFP module for low-cost 1-kb/s QKD, and (iii) novel oblivious transfer and quantum FPGA systems. Network-integration and system evaluation in real fibre networks will be enabled by quantum-aware software defined networking and field trials in the live Smart-City demonstrator Bristol-is-Open. The power of the developed ecosystem will be also validated by pushing current QKD-centric work into higher grounds, and demonstrating one-time programs and secure database access through oblivious transfer. The trans-disciplinary approach of UNIQORN brings together leading European players from quantum optics and photonics enabling to move from lab science to field deployment and bridge the quantum divide between large (governmental) and small (residential) end-users.

Keywords: quantum communication,quantum assisted one time programs,quantum oblivious transfer,dps qkd,cv qkd,entangled photon source,quantum systems on chip,applications for quantum networks,qrng
Supplying bioactives Compounds from micro-Algae to foster a bLue futurE (SCALE)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Public-private partnerships
Destination: Bio-based Industries
Action type: Innovation actions
Partnership: BBI (Art-187)
Countries involved: Spain,Spain,Belgium,Norway,France,France,France,France,France,France,United Kingdom
Call: Produce food ingredients with high nutritional value from aquatic sources (H2020-BBI-JTI-2020, 2020)
Start date: 2021-06-01
End date: 2025-05-31
Duration (months): 48.0
Total project cost (EUR): 24493007.41
EU funding (EUR): 14304045.22
Participants: 12
Project status: SIGNED

The current food system is seriously challenged by evolving consumers needs and by the rapid world population growth, which could peak to 9.7 billion people in 2060. To provide food system with high nutritional value ingredients, it becomes of paramount important to harness the potential of the oceans in an environmentally responsible manner. Microalgae are a highly promising source of aquatic biomasses and find applications in a wide range of fields, including nutrition and well-being. Currently, no large-scale industrial production site provides access to the exceptional biodiversity of microalgae in an efficient way. Only a few species are produced globally with dedicated production sites. For instance, 70% of the market is currently represented by Spirulina and Chlorella. The SCALE project strives to build and operate a first of its kind Flagship plant producing ingredients with high nutritional value derived from the untapped microalgae diversity, for food, food supplements, feed and cosmetics sectors, through economically-sound processes and in an environmentally friendly way. This Flagship project is based on the unique and cutting-edge CAMARGUE photobioreactor technology developed and patented by Microphyt, a French leading SME in microalgae-based natural solutions for nutrition and well-being. The CAMARGUE technology currently operating and running at demo plant offers both high differentiation potential and the ability to supply natural active ingredients in an industrial and standardized way. SCALE will transfer this technology from the demo plant to the industrial Flagship plant able to produce large-scale volumes of high-value ingredients of unique microalgae species that cannot be supplied from other production technologies. To do so, SCALE project gathers 12 key EU and international partners in an integrated value chain from microalgae production to high value ingredients extraction of bioactives compounds and end-use applications in food, food supplements, feed, and cosmetic domains.

Keywords: microalgae,photobioreactors,high value compounds,tubular system,application feed,food,cosmetic,food supplement
uPROPHET: Urinary PROteomics in Predicting HEart Transplantation outcomes (uPROPHET)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Belgium
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-10-01
End date: 2018-03-31
Duration (months): 18.0
Total project cost (EUR): 147500.0
EU funding (EUR): 147500.0
Participants: 1
Project status: CLOSED

The proof of concept underlying uPROPHET rests on the EPLORE findings that capillary electrophoresis coupled with high-resolution mass-spectroscopy reproducibly identified unique urinary proteomic (UP) signatures associated with subclinical left ventricular dysfunction, renal impairment and adverse cardiovascular outcomes. Consensus criteria currently applied for the selection of patients for heart transplantation (HTx) leave an inconvenient margin of uncertainty, because of the unpredictable course of the disease and the shortage of donor hearts. Furthermore, monitoring graft function and adjusting immunosuppression remain major challenges after HTx. Endomyocardial biopsies, up to 20 in the first year after HTx, are the standard approach to detect graft rejection, but require an invasive risk-carrying procedure. uPROPHET aims to develop UP profiling: (1) as a prognostic tool helpful in selecting terminally ill heart failure patients for HTx with the greatest probability of survival while adding a maximum of high-quality years to life; and (2) as an instrument to monitor graft performance and immune system activity and to manage immunosuppression. The new UP classifiers will be initially validated by demonstrating analogy between the proteomic profiles in urine and tissue samples of explanted hearts. uPROPHET will show case the translation of state-of-the-art technology into “innovative services”, broaden the indications for UP, and therefore have a major impact on the plans of the business partner measuring the UP profiles. The evident benefit for the customer (patient) is the early and non-invasive stratification of risk in heart failure patients before and after HTx, hence allowing an early, personalised, and targeted approach. Clinical implementation of uPROPHET findings will bring European research to the forefront of the highly competitive fields of biomarker research and personalised medicine and impact on transplantation medicine beyond HTx.

Keywords: heart failure,heart transplantation,urinary proteomics,graft rejection,selection of recipients