Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Synthesis of innovative organic semiconductors based on functionalized tetracenes and derivatives of rubrene (TETRA-FUN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-06-01
End date: 2011-05-31
Duration (months): 24.0
Total project cost (EUR): 164877.53
EU funding (EUR): 164877.53
Participants: 1
Project status: CLOSED

Organic semiconductors represent a real alternative to inorganic semiconductors for many applications, since they present some evident advantages: are lighter, cheaper, compatible with large area, flexible devices. One of the most promising molecular organic semiconductor is rubrene (5,6,11,12-tetra-phenyl-tetracene); single crystals of rubrene showed hole mobility comparable with that of amorphous silicon. Chemists’ contribution to the research on rubrene can allow to overcome some problems still affecting this promising molecule, namely the tendency to be oxidized, the difficulty to grow crystalline thin films and the lacking of n-type homologues. Objective of this project is the synthesis of new derivatives of tetracene, homologues of rubrene, and the study of their optical and electronic properties, both at molecular and crystal level, and the comparison with rubrene, to learn about the effect of different substituents on structure and properties. The project is aimed therefore to study how different substituents and different supramolecular arrangements can influence charge transport and light emission in the solid state. 5,6,11,12-tetra-aryl-tetracene (rubrene) and homologues can be prepared starting from appropriate 1,1-diphenyl-propargyl alcohols. The first step will be the investigation of the synthesis of tri-aryl-propargyl alcohols and the synthesis of new derivatives. These compounds will be used to prepare the corresponding homologues of rubrene, optimizing the reaction conditions and studying the reaction into the details. These compounds will be the starting point to growth crystalline materials; the main target for the characterization of these materials will be the analyses of the electric properties of these materials. Part of the characterization work will devoted also to the analysis of the structure and of the optical properties (in the UV-visible range) of these materials

Keywords: organic chemistry,rubrene,tetracene,organic semiconductor
Active Rejection of Background in Rare Event Searches (ARBRES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2010-01-01
End date: 2011-12-31
Duration (months): 24.0
Total project cost (EUR): 165444.54
EU funding (EUR): 165444.54
Participants: 1
Project status: CLOSED

ARBRES (Active Rejection of Background in Rare Event Searches) is a proposal for a 24-month Marie Curie fellowship dealing with a key topic in Astroparticle physics: the tagging, the control and the rejection of the radioactive background of surface origin in rare-event searches. The scientific objective of the proposal is to extend significantly the discovery potential of searches for Neutrinoless Double Beta Decay and for WIMPs, hypothetical particles composing Dark Matter. The methods proposed here aim at improving the bolometric technique, by equipping low temperature calorimeters with thin films which enable the recognition of surface energy depositions. The fellow researcher, coming from a 4-year experience in rare event searches, will develop competencies in the technique of thin film deposition, low temperature solid state physics and detection of nuclear radiation, in a multidisciplinary framework. She will operate in a stimulating environment, in close connection with experiments at the forefront of Astroparticle physics (EDELWEISS and CUORE) and in a top-class host institution (Centre de Spectrometrie Nucleaire et Spectrometrie de Masse, Orsay, France), with a long experience in the development of technological solutions for the search for Dark Matter. She will also contribute to bridge the gap between the nearby Double Beta Decay and Dark Matter European communities. ARBRES will therefore support the future scientific career of the researcher by providing her with first-class technological competencies and stimulating her decision-making and leadership capabilities, in the framework of fundamental physics problems. Double Beta Decay and Dark Matter searches are at the centre of a hot international competition, given their relevance to understand basic properties of particles and forces and the structure of the Universe. Hence, the improvements provided by ARBRES will contribute to European excellence and competitiveness in a frontier research field.

Keywords: astrophysics,nuclear physics,astroparticle physics,galactic dark matter,neutrino physics,double beta decay,low temperature devices,bolometers,radioactivity
From communities to individuals: development of an early warning system to assess the relationship between climate warming and pollution in European freshwater ecosystems (PARAWARM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2010-03-01
End date: 2010-11-30
Duration (months): 9.0
Total project cost (EUR): 161563.92
EU funding (EUR): 161563.92
Participants: 1
Project status: CLOSED

The project addresses the interaction between parasitism and pollution in the context of climate change using parasites in freshwater fish as a model early warning system for altered environmental conditions by the application of a two-fold approach. First, a comparative assessment of the effect of temperature on parasite population and community structure dynamics will be carried out using ‘matched pairs’ control-impact design in a ‘natural experiment’ setup to test the ‘parasite numerical response’ hypothesis. Simultaneously, structural patterns in a free-living freshwater system, macrozoobentic communities, will be evaluated. Secondly, using the same sampling design the hypothesis of temperature-mediated alteration of pollutant metabolism will be tested by a comparative evaluation of the rates of toxic metal accumulation in selected dominant parasite and benthic invertebrate species. Identification of temporal and spatial patterns of abundance and community structure at different thermal regimes is the key to forecast the impacts of climate change on parasite communities in fish in European freshwater ecosystems. Further, linking ecological data to pollutant metabolism will provide novel insights on the response of parasite communities to environmental change which may help predict possible outcomes of host-parasite interaction and forecast minimum index values to detect pollution in the context of the effect of global warming. The novelty of the proposed research lies in its trans-disciplinary approach linking advanced ecology and ecotoxicology concepts and methods. The quantification of the response to increased ambient temperature of the model organism groups relates not solely to issues fundamental to assessment of climate-mediated community level alterations and host-parasite interactions but to wider conceptual and applied domains such as synergism and/or antagonism among multiple stressors and pollution risk analysis using model indicator systems.

Keywords: benthic invertebrates,bioindicators,climate change,community structure,early warning system,ecotoxicology,freshwater ecosystems,metal accumulation,parasites,pollutant metabolism.
Investigation of the O2-dependent function of HELZ, an RNA helicase interacting with the oxygen-sensing prolyl-4-hydroxylase PHD2 (HYDRELZ)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-11-01
End date: 2011-10-31
Duration (months): 24.0
Total project cost (EUR): 180801.44
EU funding (EUR): 180801.44
Participants: 1
Project status: CLOSED

A crucial step in the adaptation of mammalian cells to oxygen deficiency is the transcriptional activation of hypoxia-inducible genes. Hypoxia-inducible transcription factors (HIFs) are master regulators for the up-regulation of these genes under physiological as well as pathophysiological conditions, such as tumor development and metastasis, cardiovascular diseases and inflammation. HIFs are O2-dependently hydroxylated at conserved prolyl residues by recently discovered prolyl-4-hydroxylase domain proteins (PHDs). Therefore, PHDs function as molecular oxygen sensors by determining the protein stability of HIFα subunits. Importantly, non-HIFα proteins have been reported to represent PHD hydroxylation substrates, indicating that O2-dependent prolyl hydroxylation might be a more common post-translational modification than previously expected. The aim of this grant application is to study the function of the RNA helicase HELZ that was identified to interact with PHD2. HELZ has been shown to be important for the function of SMYD3, a histone lysine methyltransferase which has been implicated in tumorigenesis. Preliminary data demonstrate O2-dependent regulation of HELZ protein abundance and suggest that HELZ might be a novel PHD2 hydroxylation substrate. The goal is to generate a conditional HELZ gene targeting model to characterize the O2-dependent function of HELZ in vivo and to investigate PHD2-dependent HELZ protein hydroxylation by mass spectrometry.

Keywords: cancer research,genetic engineering,hypoxia,prolyl-4-hydroxylase,hif,rna helicase,knock-out mouse model,health sciences
Textile Fibre in Italy Before Roman Empire (FIBRE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-10-01
End date: 2011-09-30
Duration (months): 24.0
Total project cost (EUR): 236933.2
EU funding (EUR): 236933.2
Participants: 1
Project status: CLOSED

The FIBRE project investigates the development and use of textile fibres in Italy from prehistory until the Roman period. Wool and flax fibres constitute a nexus between agriculture and textile craft, two of the oldest and socio-economically most important human technologies. Issues addressed through the investigation of archaeological fibre include ancient agriculture, husbandry, trade and economy, development of new strategies of fibre acquisition, diversification and spread of sheep breeds throughout Europe. Yet, ancient fibres have never been investigated in this complex context. Ancient Italy serves as this project’s point of departure since by Roman times it produced some of the best wool and linen but is the least investigated area in European fibre and textile archaeology. The FIBRE Project examines the various sources of information available for the investigation of ancient fibre, including archaeological textiles, archaeobotanical and archaeozoological assemblages, palaeoecological and geological record, as well as ancient literary and iconographic sources The objectives of the project are to elucidate endogenous development of textile fibres in Italy and their spread throughout Europe and the Mediterranean; to evaluate the old and to develop new fibre analytical methods and ways of interpreting obtained data; to integrate fibre studies into research of broader archaeological questions. The project aim is thus to demonstrate the potential of archaeological fibre for the investigation of ancient craft and agriculture, thereby having a major impact on archaeometric methodology, textile and fibre archaeology and European economic and agricultural history.

Keywords: fibre,textile,agriculture,breed,craft,archaeobotany,archaeozoology,italy,humanities
Genomics data mining for the genetic analysis of populations of the Dutch elm disease (DED) fungi (Ophiostoma ulmi and O. novo-ulmi). (GENODED)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-IOF-2008, 2008)
Start date: 2009-11-01
End date: 2011-10-31
Duration (months): 24.0
Total project cost (EUR): 198267.06
EU funding (EUR): 198267.06
Participants: 1
Project status: CLOSED

RAPD analyses have shown that two inter-fertile fungal species causing the Dutch elm disease (DED) (Ophiostoma ulmi and O. novo-ulmi) coexist in elm stands in Europe, together with their interspecies hybrids. This constitutes an opportunity for a rapid emergence of new pathogenic races via interspecific gene flow. However, due to the drawbacks of the RAPD technique, new molecular markers should be designed to investigate the evolution of the pathogen populations. This project will enable the fellow to acquire the needed knowledge on the genomics of DED fungi to develop new molecular markers, in order to analyse the evolution of the populations of these pathogens in European elm stands. In the partner organization (Laval University, Canada), the fellow will develop the new markers by a mining of Ophiostoma genomics data obtained at this Canadian University. At Laval University the research program will include: (i) screening Ophiostoma ESTs libraries for microsatellites and PCR-RFLP; (ii) designing PCR-markers for several polymorphic fitness/pathogenic genes; and (iii) developing PCR-markers to detect genome changes generate by transposition of transposable elements (TEs). In the return institution (Polytechnic University of Madrid, Spain) the fellow will study the populations of the pathogens, and the evolutionary mechanisms that might lead the pathogens to overcome the elm resistance of breeding programs. The study of the populations will comprise: (iv) the levels of sexual reproduction, hybridisation and introgression; (v) the genetic structure and gene flow among populations; and (vi) the analysis of the polymorphism generated by TEs in order to investigate whether their activation increases the genetic diversity of the pathogen populations. Two potential evolutionary scenarios will be investigated: populations of the DED pathogens in equilibrium (sensitive elm stands), and under selection (tolerant elm stands).

Keywords: dutch elm disease,elm,fungal populations,genetic diversity,ulmus,molecular markers,ophiostoma,forest pathogens,pathogenic fungi
Sound use for orientation by marine fauna, an ecosystem approach considering anthropogenic noise. (SOUNDMAR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-IOF-2008, 2008)
Start date: 2010-03-01
End date: 2013-02-28
Duration (months): 36.0
Total project cost (EUR): 297014.18
EU funding (EUR): 297014.18
Participants: 1
Project status: CLOSED

Many marine animals use active and passive acoustics for a range of biological functions taking advantage of the low attenuation of sound in water and. Rising levels of acoustic pollution have the potential to impact negatively on groups of marine fauna, such as cetaceans, known to rely on sound to communicate and forage. There is novel and growing evidence for the use of ambient sound in orientation in other marine fauna at the base of the trophic net, particularly larval fish and crustacea searching for a settlement area. This project will extend research on the usage of passive acoustic orientation by marine fauna from different trophic levels in the marine ecosystem: fish/crustacean larvae and baleen whales. The potential negative impact of anthropogenic sound on acoustic orientation of these species will be explored as well as the possible top-down and bottom-up effects of noise in the marine ecosystem. Reference data on background noise levels in the oceans are scarce, limiting our ability to detect increases in noise levels and their potential effects in sensitive marine areas. Marine acoustic pollution is pervasive and may cross boundaries of protected areas. This project will monitor levels of broadband background noise in marine Nature 2000 sites and investigate whether the design of these sites is effective at protecting fauna from noise pollution. This multidisciplinary project involves the participartion of several international collaborators and will use state of the art technology including specialised underwater equipment for larval studies, suction-cup acoustic and orientation DTAGs to investigate whales and acoustic recording and dosimeters systems, DMONs, deployed from GPS-equipped drifting buoys, for sound field mapping of marine European Special Areas of Conservation in the Canary Islands. Results will have immediate application to EU policy on anthropogenic noise in the oceans, with implications for human fisheries and biological conservation.

Keywords: animal senses,marine ecosystems and processes,animal ecology,anthropogenic impact on ecosystems
Intellectual Capital, Work and Well-being (IC-WELL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2010-01-11
End date: 2012-01-10
Duration (months): 24.0
Total project cost (EUR): 164269.69
EU funding (EUR): 164269.69
Participants: 1
Project status: CLOSED

The aim of this project is to identity how Intellectual Capital (IC) impacts upon work and well-being, and how IC may be promoted through workplace policies. Research will be undertaken in Bulgaria, Finland and Scotland; EU member states with varied economies, social and welfare polices. Data will be collected from national and EU organisations, and SMEs in the study countries in the growth sectors of ICTs, finance, care services and tourism. The research draws upon the disciplines of economics, sociology and industrial management. Since the Lisbon Strategy of 2000 , many political and legal measures have continued to reflect the EU objective of becoming ‘the most competitive knowledge-based economy in the world’ (Lisbon, 2000 and subsequent strategies). There has, only been limited research on the links and interactions between IC, work and well-being. IC includes forms of knowledge that are generated and exploited. Technological, social and economic developments have placed increased focus upon IC and today it is a basic component of knowledge businesses. Over 24 months the fellow will undertake: - a comparative scoping exercise to identify legislation, policies and practices at the EU and the member states in this project - a survey of 30 companies in each country will be undertaken to establish the policies and practices in place in SMEs in growth sectors to identify and support IC and workers - 10 interviews will be undertaken in each country to allow for exploration of survey data. Interviewees will be drawn from workers to managers and national IC organisations - develop models and practices for supporting IC -on-going dissemination which will include diverse media and audiences. The project will make a contribution on how to support the development and exploitation among SMEs and the workforce. The project will have a positive impact on fellow’s academic growth and professional maturity.

Keywords: intellectual capital,work,well-being,knowledge,innovation,scoial contract
Heavy Ion Collisions at the LHC: Strong coupling techniques for high density QCD (HICLHC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-06-01
End date: 2011-05-31
Duration (months): 24.0
Total project cost (EUR): 160114.64
EU funding (EUR): 160114.64
Participants: 1
Project status: CLOSED

The study of nuclear matter under extreme conditions, where new states are predicted by Quantum Chromodynamics (QCD), is the new frontier on the physics of the strong interactions. The upcoming experimental program in ultra-relativistic heavy ion collisions at the CERN Large Hadron Collider, starting in 2009, is aimed at producing and studying a new state of matter, the Quark Gluon Plasma, and at the understanding of the fundamental properties of QCD, such as confinement and its phase diagram. The main goal of this project is to develop new theoretical tools for the analysis and understanding of the forthcoming experimental data. In this project we will use String Theory techniques to study non-perturbative aspects of Yang-Mills theories via the AdS-CFT correspondence. This novel procedure allows to study real-time dynamical aspects of a strongly-coupled Quark Gluon Plasma so far intractable via ordinary field-theoretical tools. In particular, we will study the thermalization dynamics of the very dense off-equilibrium partonic system created after a high energy nuclear collisions via the construction of a gravity-dual description of high-energy QCD scattering. Another goal of this project is to study the propagation of hard tomographic probes, such as quark and gluonic jets and heavy mesons, through a strongly-coupled medium, as well as the back-reaction induced in the medium in the form of collective excitations. The proposed studies shall be complemented and benchmarked against the available information about high density QCD systems derived in the weak coupling formalisms of the Color Glass Condensate and Finite Temperature QCD. An important ingredient of this project is the direct phenomenological application of the theoretical research work. To that end, a close contact and collaboration with different experimental groups is foreseen.

Keywords: quantum field theory,nuclear physics,string theory,heavy ion collisions,lhc,ads/cft correspondence