Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Safe and sUstainable by desigN Strategies for HIgh performance multi-component NanomatErials (SUNSHINE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Research and Innovation actions
Countries involved: Ireland,Italy,Germany,Germany,Spain,Spain,Spain,Italy,South Africa,Spain,Spain,Spain,Italy,Italy,Switzerland,Greece,Switzerland,Belgium,China,Korea, Republic of,Bulgaria,France,France,United States,Netherlands,United Kingdom,United Kingdom,Luxembourg
Call: Safe by design, from science to regulation: multi-component nanomaterials (RIA) (H2020-NMBP-TO-IND-2020-twostage, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 7859871.25
EU funding (EUR): 6521348.75
Participants: 36
Project status: SIGNED

The main goal of SUNSHINE is to develop and implement S&SbD strategies for products enabled by multi-component (advanced) nanomaterials (MCNM), including high aspect-ratio nanomaterials (HARNs). To this end, the project will generate essential knowledge, tools and data on the exposure, hazard and functionality characteristics of these materials, especially those arising from their unique properties and interactions (e.g. mixture effects due to the multi-component nature of the materials). To facilitate the uptake and utilisation of the S&SbD strategies by industry, especially SMEs, we will deliver them as part of a user-friendly e-infrastructure designed to: (1) facilitate collaboration and information exchange between actors along nanotechnology supply chains (developers, producers, downstream users) to promote the development and implementation of S&SbD strategies for MCNM-based materials, products and processes; (2) support SMEs and large industries in the selection and application of simple, robust and cost-effective experimental, modelling and grouping/read-across approaches to acquire/generate the data needed to test the effectiveness of the S&SbD strategies; (3) enable risk-benefit analysis of the S&SbD-modified materials and products at each stage of the innovation process to ensure that they are safe for the human health and the environment without compromising their technical and/or commercial probability of success The S&SbD strategies that are effective in reducing the risks from MCNMs, while retaining product performance and economic viability, will be proposed for full scale industrial implementation. In addition, the project will contribute to Regulatory Preparedness by providing recommendations on improvement and adaptation of the current regulatory hazard, exposure and risk assessment guidance (e.g. REACH, Biocides, Consumer Products, Food and Feed, Medical Technologies) and standard guidelines (OECD, ISO, CEN) for MCNMs.

Keywords: safe and sustainable by design strategies,multi component advanced nanomaterials,grouping and read across,multi scale modelling,adaptation of regulatory guidance and standards,mixture toxicity
Copper-Based Flow Batteries for energy storage renewables integration (CUBER)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: A single, smart European electricity grid
Action type: Research and Innovation actions
Countries involved: Spain,Ireland,Italy,Italy,Germany,Spain,Cyprus,Finland,Portugal,Denmark
Call: Advanced Redox Flow Batteries for stationary energy storage (H2020-LC-BAT-2019, 2019)
Start date: 2020-01-01
End date: 2023-12-31
Duration (months): 48.0
Total project cost (EUR): 3999823.75
EU funding (EUR): 3999823.75
Participants: 12
Project status: SIGNED

The CuBER project proposes the validation of a promising RFB technology, the all-copper redox flow battery (CuRFB), able to cover a wide range of the aforementioned market applications due to its simple, modular and scalable design, security and sustainability. Firstly, a 5kWDC CuRFB pilot will be designed for its integration in Smart Cities and residential self-consumption market segments within the CuBER action. Subsequently, the planning of further developments will allow its application at larger scales, both as back-up power system in isolated areas (i.e. copper mining) and for energy management and grid balancing in renewable power production. CuBER thus focuses first on improving the infrastructures for renewables self-consumption and grid integration within the Smart Cities and Net Zero Buildings concepts. It seeks to unify the expertise of different European actors in the field of Electrochemistry, Electrochemical Energy Storage, Electronics, Process Engineering, Smart Sensors, IoT´s and Solar Power Industries with the objective of deploying functional pilots capable of validating an holistic and innovative way of producing and consuming renewable energy in urban, rural and industrial areas all around the EU, that will change the actual O&M paradigm, increasing significantly the competitiveness of RFB energy storage solutions in the global energy sector and creating new business opportunities for the companies involved.

Keywords: cooper,redox flow batteries,circular economy,solar forms,electric grids
A model to study how social interaction modulates sleep in the fruit fly Drosophila melanogaster (SEX_FIGHT_SLEEP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-02-01
End date: 2019-01-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Sleep is a fascinating phenomenon and one of the least understood mysteries of biology. It is universal among the animal kingdom and most species devote a large part of their day to sleep, despite the risks of lowering their defenses against predators or not engaging in more productive activities such as foraging or mating. In many animals, social interaction is a powerful modulator of sleep quality and quantity. In nature, animals are continuously exposed to a diverse variety of stimuli, and interactions with con-specifics represent a particularly relevant set of them. For Drosophila males, interaction with females is key to ensure reproduction, while interaction with other males can create antagonistic fights to compete for sexual partners, food or shelter. Through this project, I propose to investigate if and how social interactions affect sleep need and sleep quality. Employing fruit flies it has been previously shown that male-male interaction during the night builds up sleep pressure, observable in the next day as marked increase in sleep. Recovery of sleep after sleep deprivation is also called “sleep rebound”, and in all species it is thought to be 1) at the basis of sleep homeostasis and 2) positively correlate with sleep deprivation. The longer an animal stay awake, the higher the sleep pressure and following rebound. Also, it has been described that previous sleep experience modulates antagonistic behaviours between males. Thus, bidirectional interplay between social interaction and sleep appears as a promising framework to address a main goal of modern neuroscience, understand how sleep is regulated and which sleep functions are. I intend to use new developed behavioural paradigms and software that improve sleep analysis in combination with refined genetic tools available in Drosophila to extend our knowledge on the interaction between phylogenetically conserved behaviours, social interactions and sleep, which have a high impact on reproductive fitness.

Keywords: sleep,courtship,aggression,drosophila,sleep deprivation,pheromones,neural circuits
Wearable Electronics for Effective Lung Monitoring (WELMO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Estonia,Italy,Greece,Serbia,Switzerland,Greece,Portugal,United Kingdom
Call: Electronic Smart Systems (ESS) (H2020-ICT-2018-2, 2018)
Start date: 2019-01-01
End date: 2022-06-30
Duration (months): 42.0
Total project cost (EUR): 3999675.0
EU funding (EUR): 3999675.0
Participants: 9
Project status: CLOSED

Lung related diseases such as chronic obstructive pulmonary disease (COPD), pneumonia and asthma are considered the main causes of death in the EU. The current management of such diseases only allows a momentary patient assessment at the time point of out-clinic visit or hospitalization. Short-term trends in disease development, either deterioration or improvement, are not accessible. Continuous and real-time monitoring, especially in remote settings (e.g. patients’ homes) is not available. Additionally the devices used for monitoring the patients are massive, expensive, uncomfortable and difficult to operate, thus requiring specialized personnel. Several of them also rely on patients´ cooperation and compliance to guarantee proper examination results. The incorporation of novel electronics in garments presents great potential for addressing these challenges. More specifically, the adoption of Application-Specific-Integrated-Circuits (ASICs) neatly integrated in a comfortable and washable wearable is the key that makes the accurate and effective (in terms of both, cost and quality of life) continuous monitoring of lung diseases feasible. The 42-month project WELMO aims at developing and validating a new generation of low-cost and low-power miniaturized sensors, integrated in a comfortable vest, enabling the effective and accurate monitoring of the lungs, through the simultaneous collection of sound and electrical impedance tomography (EIT) signals with the same sensors that can be combined, processed and linked with specific clinical outcomes by applying innovative algorithms, making the systematic, accurate and real-time evaluation of respiratory conditions possible. The impact, acceptance and usability of WELMO will be validated in a realistic setup through the execution of two 6-month pilot studies. In addition, a business study will be carried out, aiming to the mid-term exploitation of the proposed solution.

Keywords: respiratory diseases,lung monitoring,cooperative sensors,asic,wearables,electric impendance tomography eit,lung sounds
A molecular approach to treat diabetes mellitus onset dependent coronaropathy (DIAMONDCOR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Germany,Germany
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-01-01
End date: 2023-12-31
Duration (months): 72.0
Total project cost (EUR): 1490529.0
EU funding (EUR): 1233329.96
Participants: 2
Project status: SIGNED

In Europe, 59 million patients suffer from diabetes mellitus with health costs of 142 billion Euros per year. As one of the most challenging consequences, diabetes inflicts cardiovascular disease leading to cardiomyopathy and cardiac death. A global, current aim lies in preventing cardiac complications in patients with diabetes mellitus. In pathogenesis of diabetic cardiomyopathy, the role of microvascular processes remains largely elusive; my proposal aims at solving this key question – an impossible mission so far. As attractive therapeutic concept and overall objective, the present proposal aims at exploiting microvascular mechanisms for preventing and treating diabetic cardiomyopathy. I will study a novel, unique transgenic pig model of diabetes mellitus combined with advanced, patient compatible molecular imaging. We pioneered distinct genetic manipulations in pigs, including adeno-associated viral vectors (AAV) for microvessel stabilization as well as AAV-based CrispR/Cas9 transduction for in vivo genome editing. Using this cutting edge technology, I could decipher an important role for microvascular capillary rarefaction in the development of diabetic cardiomyopathy in my previous work. In the present proposal, I aim at determining 1. novel, microvascular-focused therapeutic targets for diabetic cardiomyopathy 2. the effect of reduced microvascular damage on myocardial function in diabetes, both in the absence and presence of ischemia. My approach will implement targeting microvessels as new paradigm for treating diabetic cardiomyopathy. I will identify novel therapeutic targets for tailored drug development by industry and academia. My planned work will improve the success rate of clinical trials for the benefit of patients suffering diabetic cardiomyopathy and putatively other cardiac diseases.
The Road to Friday of Science (ReFocuS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Serbia,Serbia,Serbia
Call: European Researchers' Night (H2020-MSCA-NIGHT-2016, 2016)
Start date: 2016-05-01
End date: 2017-12-31
Duration (months): 20.0
Total project cost (EUR): 185550.0
EU funding (EUR): 175500.0
Participants: 4
Project status: CLOSED

The Road to Friday of Science (ReFocuS) project’s aim is to extensively improve the public attention to science and its importance for society and wellbeing by bringing back the focus of the general public to researchers and the results of their studies. Inspired by the current situation in Europe concerning migrations, we aim to ReFocuS public attention to modern EU concept of: (i) mobility of researchers and ideas, as a basis for economy and social prosperity, and transdisciplinarity of the research, as the essential concept of contemporary research and communication. Moreover ReFocuS aims to refocus: the young minds to be open to functional learning, and to be ready to accept the opportunity to be scientists; the scientists to be approachable because their results are important for not just the academics, but to the society as a whole; and the general audience to be aware of the fact that science is a key to everyday life improvement and progress. The ReFocuS is supported by two main pillars: Night 2016 will be focused on "Roads", while Night 2017 will be focused on "People". "Roads" is intended to describe the importance of ancient and contemporary routes as a foundation for the modern European science, as well as to understand and respect the effects of migration. "People" is devoted to mobility of researchers and ideas via ancient roads that affected present variability of people, traditions, social backgrounds, languages, heritage and culture. We will model the migrations influence on today’s society in a scientific way, and show the transdisciplinarity of science to youths and general public. The base of ReFocuS is the encouragement of scientists to stand out and explain the importance of migrations on various levels. The ReFocuS project's major strength is the high mobilization of researchers, and the numerous activities taking place on main busy streets and historical sites of the seven Serbian cities, which will have a high social impact in the region.

Keywords: migrations,roads,people
Integrated, Fail-Operational, Cognitive Perception, Planning and Control Systems for Highly Automated Vehicles (NewControl)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Public-private partnerships
Destination: Electronic Components and Systems
Action type: Research and Innovation actions
Partnership: ECSEL (Art-187)
Countries involved: Germany,Spain,Italy,Italy,Italy,Austria,Austria,Germany,Germany,Germany,Spain,Italy,Italy,Germany,Italy,Italy,Austria,Cyprus,Belgium,Finland,Finland,Türkiye,Belgium,Belgium,Finland,Lithuania,France,France,Czechia,Czechia,Netherlands,Netherlands,Netherlands,Netherlands
Call: H2020-ECSEL-2018-2-RIA (H2020-ECSEL-2018-2-RIA-two-stage-1, 2018)
Start date: 2019-04-01
End date: 2023-03-31
Duration (months): 48.0
Total project cost (EUR): 37307279.46
EU funding (EUR): 10914717.33
Participants: 51
Project status: SIGNED

NewControl will develop virtualized platforms for vehicular subsystems that are essential to highly automated driving (realizing functions such as perception, cognition and control), so as to enable mobility-as-a-service for next generation highly automated vehicles. Its overarching goal is to provide an industrially calibrated trajectory towards increased user-acceptance of automated control functions, through an approach that is centered on the premise of safety by design. Newcontrol will deliver: 1. Fail-operational platform for robust holistic perception through a combination of Lidar, Radar, and sensor fusion 2. Generalized virtual platform for stable and efficient control of propulsion systems 3. Cost- and power-efficient, high-performance embedded compute-platforms for in-vehicle perception, cognition, and control 4. Robust approaches for implementing, verifying, and certifying automated control for safety-critical applications Several (12) demonstrators will be built to showcase the project’s findings and their capability to facilitate perception, cognition and control of next generation highly automated vehicles. The developments in NewControl will facilitate significant cost reductions for essential modules necessary for future automated vehicles. Concomitantly, these developments will improve the safety and reliability of automated systems to levels necessary for mass-market deployment. These innovations will leverage the expertise of industrial (OEMs, Tier-1, Tier-2 and technology providers) and research partners along the complete semiconductor, automotive, and aviation value chains, providing Europe with a competitive edge in a growing market. Importantly, NewControl's innovations will improve the market penetration of safety-centric automation systems, contributing directly to the European goal of zero road fatalities by 2050.

Keywords: fail operational,highly automated vehicle,lidar,radar,fusion
Global Maghreb: Transnational Recognition and Knowledge of a Postcolonial Literature (GLOMAG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2025-08-01
Duration (months): 36.0
Total project cost (EUR): 183709.92
EU funding (EUR): 183709.92
Participants: 2
Project status: SIGNED

Global Maghreb: Transnational Recognition and Knowledge of a Postcolonial Literature offers a groundbreaking approach to the study of Postcolonial literatures and, more generally, literary history, by (1) promoting a genuinely interdisciplinary approach that spans both literary studies and the social sciences (i.e., sociology, history); (2) reframing the “national literature” used in literary studies with a transnational (and multilingual) perspective; and (3) questioning the Postcolonial in the context of Globalization. The objective is to understand the impact of transnational circulation of texts and writers on literary recognition, as well as to historicize the transnationally produced knowledge of these literatures. The research is focused on North-African countries that gained independence from France in the 1950s/1960s (i.e., Morocco, Algeria, Tunisia) and examines them in an international landscape (ie., French, Arabic, English). The work is divided into three case studies. (1) “Transnational intermediation of Maghreb literature” develops a macro understanding of the circulation of texts, using a bibliographical database and interviews with translators and other intermediaries of the transnational circulation. (2) “Female Maghreb Writers in the USA and France” compares the literary/political reception of female writers and their work in the two countries. (3) “Transnational creation of a national literature” historicizes the nationalization of “Tunisian literature” and the exclusion of writers for political (European writers after independence), religious (Jewish writers), ethnic (Black writers) or linguistic (Francophone) reasons, and highlights the ongoing struggles on this literature’s “identity.” The dual objectives of Recognition and Knowledge are inherently political. As such, GLOMAG is an original and effective means to combat (1) global cultural hierarchies, and (2) prejudices regarding so-called “identities” (especially those concerning Muslims).

Keywords: transnational,postcolonial,globalization,multilingual,translation,north africa,france,national,literature,sociology of literature,gender,statistics,interviews,french,arabic,english
Modelling and evaluating the socio-economic impacts of research and innovation with the suite of macro- and regional-economic models (MONROE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Innovative societies
Action type: Research and Innovation actions
Countries involved: Germany,Switzerland,Greece,Netherlands,United Kingdom,United Kingdom
Call: Better integration of evidence on the impact of research and innovation in policy making (H2020-SC6-CO-CREATION-2016-1, 2016)
Start date: 2017-01-01
End date: 2019-03-31
Duration (months): 27.0
Total project cost (EUR): 1818715.0
EU funding (EUR): 1498902.5
Participants: 6
Project status: CLOSED

MONROE aims at developing a modelling toolkit that would allow a broad range of stakeholders such as European and national governments, academia, regional and local bodies to quantitatively evaluate the impacts of their specific R&I policies and programmes. The toolkit will assess medium and long-term impacts of R&I policies and programmes on economic growth, job creation, competitiveness, social inequality and sustainability at various geographical levels ranging from word-wide to European, country and regional levels and for various economic sectors. Using innovative modelling methodologies and online visualisation techniques the developed toolkit will encourage collaboration between different societal actors in the process of co-creation for sustainable R&I driven economic growth.

Keywords: macro economic modelling,impacts of randi,empirical methods