Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
OPEn-air laboRAtories for Nature baseD solUtions to Manage hydro-meteo risks (OPERANDUM)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Fighting and adapting to climate change
Action type: Innovation actions
Countries involved: Ireland,Australia,Germany,Italy,Austria,Germany,Italy,Italy,Italy,Spain,Italy,Hong Kong,China,Greece,Finland,Greece,Slovakia,France,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Large-scale demonstrators on nature-based solutions for hydro-meteorological risk reduction (H2020-SC5-2017-TwoStage, 2017)
Start date: 2018-07-01
End date: 2022-12-31
Duration (months): 54.0
Total project cost (EUR): 14696501.68
EU funding (EUR): 12257343.25
Participants: 31
Project status: SIGNED

Severe hydro-meteorological phenomena are having a high impact in European territories and are of global concern. The science behind these phenomena is complex and advancement in knowledge proceeds with progress in data acquisition and forecasting useful for real-scenario interventions. The employment of nature-based solutions (NBS) to mitigate the impact of hydro-meteorological phenomena is not adequately demonstrated, still uncoordinated at the European level, therefore not reaching full potential. Actions to achieve highest NBS impact requires strategies to enhance societal acceptance, policy strengthening while demonstrating advantages for market development. The objective of OPERANDUM is to reduce hydro-meteorological risks in European territories through co-designed, co-developed, deployed, tested and demonstrated innovative green and blue/grey/hybrid NBS, and push business exploitation. It aims provision of science-evidence for the usability of NBS, best practices for their design based on participatory processes. It foresees a multiple level of stakeholders engagement from the local community up to the international level to leverage widest possible NBS acceptance to promote its diffusion as a good practice. It establishes the framework for the strengthening of NBS-based policies according to local legislation and promotes technology and innovation in NBS to create a European leadership. OPERANDUM is based on open-air laboratories (OALs), a fairly new concept that expands the Living Labs to a wider vision for natural and rural areas. In OALs novel NBS in seven European countries and three in China and Australia are implemented to address specific risks and their effectiveness, assessed through innovative monitoring systems and cutting-edge numerical modelling approaches. OPERANDUM realizes a multi-dimensional open and flexible platform enabling stakeholders and end users to improve knowledge in NBS to mitigate climate change as well as ways to promote and exploit the improved/preserved environment while increasing business opportunities.

Keywords: climate change,copernicus,data fusion,hydro metereological hazards,adaptation,co design
Electric Vehicle Charging Infrastructure for improved User Experience (eCharge4Drivers)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Innovation actions
Partnership: EGVI (cPPP)
Countries involved: Italy,Italy,Italy,Italy,Austria,Germany,Germany,Germany,Spain,Spain,Italy,Italy,Belgium,Türkiye,Greece,Greece,Sweden,Belgium,Greece,France,France,Netherlands,United Kingdom,Luxembourg
Call: User centric charging infrastructure (H2020-LC-GV-2019, 2019)
Start date: 2020-06-01
End date: 2024-05-31
Duration (months): 48.0
Total project cost (EUR): 18316318.75
EU funding (EUR): 14424526.39
Participants: 35
Project status: SIGNED

The sales of electric vehicles (EVs) are increasing but their drivers still encounter problems to find appropriate charging options. The vision of eCharge4Drivers is to focus on the users and substantially improve the EV charging experience within cities and on long trips, making it better than refuelling an ICE vehicle. The work will start with wide surveys in 10 demonstration areas, to capture the a priori users’ perceptions and expectations as regards the various charging options and their mobility and parking habits. Based on the survey findings and after matching with the perspective of authorities, operators and service providers, the project will develop and demonstrate in 10 areas, including metropolitan areas and TEN T corridors, easy-to-use, scalable and modular, high- and low-power charging stations, low-power DC charging stations and components with improved connection efficiency and standardised stations for LEVs. All stations will offer various direct payment methods and bigger user-friendly displays. The charging stations and all actors’ back-ends will support the ISO 15118 Plug & Charge feature and will enable the standardised transfer of enhanced information in the ecosystem, thus enabling the interoperability of communication and the provision of more sophisticated services to the users before, during and after the charging process, including smart charging services. The project will demonstrate additional convenient charging options within cities, a mobile charging service, charge points at lamp posts and networks of battery swapping stations for LEVs. Using the knowledge generated, the project will propose an EV Charging Location Planning Tool to determine the optimum mix of charging options to cover the user needs, recommendations for legal and regulatory harmonisation and guidelines for investors and authorities for the sustainability of charging infrastructure and services.

Keywords: scalable charging stations,efficient low power dc charging,charging stations for levs,alternative charging options,location planning tool,guidelines,recommendations
Time-Resolved Electron Spectroscopy of a Challenging Highly Innovative Collective Excitation Study (TRES-CHIC-ESt)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-04-01
End date: 2023-03-31
Duration (months): 24.0
Total project cost (EUR): 174167.04
EU funding (EUR): 174167.04
Participants: 1
Project status: CLOSED

Plasmons are collective modes of the solid-state electrons representing a characteristic elementary excitation in solids. In theory plasmons are simplified as quasi particles with a well-defined energy and momentum from the instant of their creation to their decay. The dynamics of plasmons and the concomitant liberation of solid-state electrons is not yet fully understood. It is the aim of the present project to unveil the dynamics of this complex many-body process with unprecedented temporal resolution. The fundamentals of plasmonics are at the core of this project, as well as technologies involving secondary and hot electrons. Albeit challenging, the above scientific vision of the applicant is not only innovative, but it is timely and relevant to various scientific and technological fields ranging from space technology, to photovoltaics and semiconductor industry, as well as life sciences and biology. With the advent of modern time-resolved experiments, the objective of the experienced researcher (ER) outlined above has realistically come within reach. The TRES-CHIC-ESt project will be carried out at a host institution which is a pioneer in the field of attophysics under a supervision offering optimal conditions for young researchers to widen their scientific horizon and to boost their careers, thus offering to the applicant the ideal environment to pursue her innermost desire: to become a world-class successful researcher. In exchange, the solid-state Physics background of the ER will enrich the perspectives of the hosting group, who among others will benefit from her prior experiences and collaborations. During her PhD-studies, as a MSCA ITN fellow, the ER has already studied the causal relationship between plasmons and secondary electrons using spectroscopy with correlated electron pairs. Finally, by following the example of successful female researchers with whom the ER collaborates, she is determined to improve the gender balance in her scientific environment

Keywords: time resolved photoelectron spectroscopy,collective excitations of the solid state,plasmons,quasi particles,many body phenomena,secondary electron emission,fundamental electronic excitations
Fighting the X. fastidiosa threat to EU agriculture - Novel smart biopesticides based on bacterial spores (SMART-AGRI-SPORE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2024-08-31
Duration (months): 36.0
Total project cost (EUR): 259398.72
EU funding (EUR): 259398.72
Participants: 1
Project status: SIGNED

EU agriculture is facing an unparalleled threat by the pest Xylella fastidiosa, potentially causing an annual production loss of ‎5.5 billion euros and putting at risk 300.000 jobs if its expansion cannot be contained. Hence, the eradication of this bacterium remains a key priority of the EU. Yet, no field treatment is currently available, highlighting the dire need for effective pesticides against this menace. At the same time the European Commission’s ambitious Green Deal and its Farm to Fork strategy set the reduction by 50% of the use of chemical pesticides by 2030 as a key priority. However, today, the availability of biological alternatives is limited and novel solutions targeting the most detrimental pests are urgently needed. In light of these challenges, we propose the development of a novel, smart biopesticide based on bacterial spores (SMART-AGRI-SPORE), specifically targeting X. fastidiosa in infected trees and insect vectors. Although the use of spores in medical applications is well established, here we extend the concept for the first time to an agricultural use by engineering spores as a biopesticide delivery vehicle. To do so, Bacillus candidates will be isolated from orchards and vectors, while an activity screen will identify novel antimicrobial peptides efficiently targeting X. fastidiosa. Spores will be engineered to express and store these active agents in the core or coat, shielding them from physicochemical and biological degradation through the protective spore structure. Using an innovative design approach, the heterologous protein will be released into the environment during induced autolytic germination. This study will provide novel insights into the treatment of X. fastidiosa under field conditions, while also extending our repertoire of alternative biopesticides for use in EU agriculture. In a wider context the project seeks to contribute to transforming EU agriculture into a modern, resource-efficient and resilient sector.

Keywords: xylella fastidiosa,bacillus,bacterial spores,biopesticides,targeted delivery,smart compound delivery,antimicrobial peptides,bacteriocins,genetic engineering,pest management,olive agriculture
Patterning Spin-Wave reconfIgurable Nanodevices for loGics and computing. (SWING)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Italy,United States
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-11-01
End date: 2019-10-31
Duration (months): 36.0
Total project cost (EUR): 244269.0
EU funding (EUR): 244269.0
Participants: 2
Project status: CLOSED

Spin-waves, i.e. propagating perturbations in the spin arrangement of magnetic materials, are envisioned to revolutionize the way information is carried and processed due to their multiplexing capability and absence of Joule losses. By bringing together the complementary expertise of “CUNY Advanced Science Research Center” (USA) and “Politecnico di Milano (PoliMi)” (Italy), the ‘SWING’ project addresses two major issues of current nanoscale magnonics: the efficient guidance of spin-waves in nanostructured materials and the study of spin-waves at the nanoscale. At CUNY, “Thermally assisted magnetic scanning probe lithography” (tam-SPL), recently conceived and demonstrated by the applicant, will be further developed and employed for nanopatterning magnonic devices in magnetic multilayers grown at PoliMi. In such devices, spin-waves will be efficiently guided and manipulated by defining reconfigurable topological features, such as magnetic domain walls, in continuous films, avoiding any detrimental scattering due to the physical interfaces created by conventional lithography. Furthermore, a novel, versatile tool for the nanoscale study of magnons will be realized, by combining Nitrogen-Vacancy magnetometry and scanning probe microscopy. Advanced magnetic characterization via optical methods, experiments at Brookhaven Synchrotron and access to the cutting-edge CUNY NanoFab facility will be pivotal complements in view of the research objectives. During the incoming phase, the acquired expertise and technologies developed at CUNY will be transferred to PoliMi, aiming to realize fully reconfigurable nanoscale magnonic logic devices. ‘SWING’ project aims to push magnonics forward, by means of an interdisciplinary approach which combines the excellent competence of the host organizations in magnetism, nanoscience, photonics and entrepreneurship. The candidate will acquire key comprehensive skills towards becoming an independent scientific and technological leader in Europe.

Keywords: scanning probe microscopy,spin wave,magnonics,nitrogen vacancy,scanning probe lithography,exchange bias
Assessing the State of the Art and Supporting an Evidence-Based Uptake and Evolution of Open Service Platforms in the Active and Healthy Ageing Domain (PlatformUptake.eu)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: Coordination and support actions
Countries involved: Spain,Spain,Germany,Italy,Austria,Sweden,Greece,Slovenia,Belgium,Netherlands,Netherlands,Portugal
Call: Support for the large scale uptake of open service platforms in the Active and Healthy Ageing domain (H2020-SC1-DTH-2019, 2019)
Start date: 2020-01-01
End date: 2022-05-31
Duration (months): 29.0
Total project cost (EUR): 1447421.25
EU funding (EUR): 1447421.25
Participants: 12
Project status: CLOSED

Ageing presents one of the greatest socio-economic challenges of the 21st century. According to estimates more than 20% of Europeans will be 65 or older by 2025. Reacting to related puzzlements of demographic shifts and ageing in general, and guaranteeing the availability of the required structure to help Europe utilise the active and healthy ageing sector’s opportunities, the EU has devoted a high level of resources to ICT projects in the field of active and healthy ageing. As such a considerable number of open source platforms for the development of innovative solutions in the AHA domain have been created. These platforms, such as universAAL and FIWARE and several others, are operational on similar services within the same domain, either competing or complementing each-other, urging for more interoperability among them. Responding to the numerous critical voices that have been raised due to the persisting fragmentation of the active and healthy ageing market; and the lack of interoperability of the various solutions deployed or difficulties with the large scale uptake of the platforms by their targeted users, the aim of the PlatformUptake.eu project is to observe, analyse and understand the whole ecosystem of open service platforms and their related networks, and depict a picture describing the whole ecosystem with its achievements and potentials, targeting all user groups while also generating synergies among platforms and their related projects in the AHA and IoT domain. For a period of 26 months, the PlatformUptake.eu project will assess the societal impact of existing platforms, create monitoring and evaluation toolkits, collect successful user stories and best practices, promote interoperability and define guidelines for a common evolution of such platforms within existing policy frameworks and initiatives. Seeking to support the large-scale uptake of the platforms, PlatformUptake.eu proposes the creation of an online information hub which provides descriptive and support materials on all existing platforms, the organisation of several stakeholder events, as well as a Massive Open Online Course for promoting synergies, knowledge exchange and a common understanding among all stakeholders in the Active and Healthy Ageing market.

Keywords: open service platforms,universaal,fiware
Regulation of cell size and shape in bacteria (RCSB)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: France
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-04-01
End date: 2021-01-31
Duration (months): 58.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: CLOSED

Proper cell size and shape are important for many biological functions, such as metabolism, signaling, motility, and development. This proposal addresses the fundamental question of how bacteria control their morphology and their cell volume with high precision, using the rod-like bacterium Escherichia coli as a primary model system. Bacterial cell shape is physically determined during growth by the enzymatic expansion and remodeling of the peptidoglycan (PG) cell wall, a partially ordered elastic meshwork that is the pressure-bearing component of the cell envelope. In this proposal we will address two fundamental questions: i) How do cells physically build and remodel their macroscopically ordered cell wall to reproducibly acquire cell shape? We will thus image the dynamics of the PG cell wall and of the enzymatic and structural proteins involved in its expansion, using high-precision video fluorescence microscopy and spectroscopy. From spatio-temporal correlations measured in steady-state experiments and after physical, chemical, or biological perturbations, we will deduce how different physical cues affect and regulate cell-wall expansion. ii) How do bacteria regulate their own cell volume, and what role does intracellular crowding play in this context? The intracellular mass density of bacteria is remarkably well conserved during growth, suggesting that cell size is regulated to maintain a constant level of intracellular crowding. Crowding has been deemed important for the regulation of volume in slowly growing mammalian cells before. Here, we will study the role of intracellular crowding, osmotic pressure, and other physiological quantities on cell-volume regulation in bacteria. Furthermore, we will use phenotypic screening and genetic approaches to identify the pathways involved in cell-volume control. Together, this proposal addresses a fundamental question of self-organization in biology using combined approaches from physics and biology.

Keywords: bacterial growth,cell size homeostasis,peptidoglycan cell wall,super resolution fluorescence microscopy
Defining of human adaptive immune gene diversity and its impact on disease (IMMUNEDIVERSITY)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Sweden
Call: ERC Advanced Grant (ERC-2017-ADG, 2017)
Start date: 2018-12-01
End date: 2024-11-30
Duration (months): 72.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Why do vaccines protect some people but not all? Why can some people develop potent neutralizing antibodies to infections, while others cannot? Why do some people develop immune-associated diseases such as allergy, rheumatoid arthritis, multiple sclerosis and diabetes over their lifetimes, when the body has evolved to tolerate self? The answer lies in the adaptive immune system. B and T lymphocytes of the adaptive system express highly polymorphic receptors that allow for the recognition of large numbers of antigens. Our research is now uncovering an enormous heterogeneity in the germline genes that encode our B and T cell receptors. This fact has not been well appreciated because of the high complexity of the genomic regions that encode these receptors, with the presence of large insertions and deletions, a high degree of repetitiveness and gene copy number variations, which cannot be adequately met with conventional whole genome sequencing approaches. We have developed a state-of-the-art approach we call IgDiscover, which comprises novel molecular library preparation approaches, next generation immune repertoire sequencing, computational analysis and a software that allows rapid construction of personalized antibody gene databases encompassing the hundreds of germline gene segments that rearrange to make up each individual’s naïve B cell repertoire. Thus, IgDiscover offers new possibilities to define human genetic diversity in these loci. This proposal also describes our development of ImmuneDiscover, a high throughput approach enabling personalized immune-profiling of very large numbers of individuals (>1000), encompassing not only Ig genes but also T cell receptor genes and the genes encoding the human major histocompatibility complexes. Here, we will use IgDiscover and ImmuneDiscover to elucidate global diversity in adaptive immune genes and we will investigate potential associations between antibody germline genes and the development of rheumatoid arthritis.

Keywords: antibody,b cell,germline antibody genes,allelic diversity,personalized immunedatabase