Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
World's First Real-Time Monitoring System for Ablation Procedures (BioTrace)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-04-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Cancer treatment resection or surgery is currently the gold standard to remove tumours, but it is risky for patients and a costly process (average cost of €28.000 per surgery). Ablation is a minimally invasive technique and the best alternative to surgery (€1,300). However, its use is still limited to treat patients with smaller tumours or patients unfit for surgery, due to its high unpredictability, as there is currently no way of knowing the extent of the lesion during and after the intervention (cells continue dying for up to 24 hours after the intervention due to thermal effects). Thus, undertreatment or over treatment frequently occur, the latest leading to up to 40% recurrence. Our solution, BioTrace, is the only device able to monitor in real-time the extent of the lesion during the ablation procedure and predicts its outcome 24 hours post-treatment. It works by keeping track of the tissue's biological response to the heat using AI-based algorithms. With BioTrace physicians are alerted when damage is observed outside the surgical margin, which enables them to determine its progression 24 hours after the procedure (as proven in a clinical study conducted with 54 standard TA procedures in University of Tokyo Hospital (UTH)). BioTrace will be a game-changer in the ablation technology industry by improving success rates and reducing costs for the healthcare system. Its market opportunity is large since it can be applied not only in the interventional oncology area, but in other areas, such as electrophysiology (for treating cardiac arrhythmias) and neurotomy (for pain management). We foresee that we will need €3 million to complete phase 2 and reach the liver market as a standalone system. Considering a growth of the global ablation market of 35% (2017-2023), in the fifth year of sales we estimate to reach revenues of 10.8M and a ROI of 0.38. During the feasibility study we will further assess the technical, commercial and financial viability of our project.

Keywords: cancer,liver cancer,arrhythmia,atrial fibrillation,cardiovascular diseases,ablation,artificial intelligence,deep learning
A natural and biodegradable nanocellulose alternative to plastic barrier coatings (EcoFLEXY)

Framework: Horizon 2020 — Societal Challenges
Action type: SME instrument
Countries involved: Denmark
Call: H2020-EIC Accelerator pilot –SME Instrument - Green Deal (H2020-EIC-SMEInst-2018-2020-4, 2020)
Start date: 2021-04-01
End date: 2023-09-30
Duration (months): 30.0
Total project cost (EUR): 3400920.0
EU funding (EUR): 2380644.0
Participants: 1
Project status: SIGNED

Plastic pollution is a dramatic problem of our times. A large percentage of plastic production is destined to packaging, which is designed for single use but at the same time can stay in the environment for thousands of years. Efforts to replace conventional, oil-based plastics with more environmentally friendly materials have so far failed due to their reliance on food crops and end-of-life challenges. Cellugy has designed EcoFLEXY, a biomaterial able to replace plastics in several packaging applications, which is completely harmless to the environment. EcoFLEXY is produced by bacteria and yeast starting from sugar or agro-industrial waste, in low-energy conditions. Being made of nanocellulose, EcoFLEXY can be either recycled in the paperboard stream or home composted, whereas if leaking into the environment it safely biodegrades in a short time, leaving no toxic residues behind. EcoFLEXY production emit 94% less CO2 emissions compared to conventional plastics and at the same time enables a circular economy by making use of second-generation feedstocks. Cellugy will first sell EcoFLEXY to packaging companies and chemical companies serving them. It will start marketing Cellugy in Northern Europe where consumer and customer demand for sustainable products is highest. EcoFLEXY will be sold at a price competitive to that of bioplastics, leveraging on important collaborations within the chemical and packaging industry. To reach market launch, Cellugy will expand its production from the laboratory to a full industrial volume scale in a stepwise manner, with considerable interest from prospective investors in the biotech sector to follow product development. Cellugy’s team is well-rounded and led by award-winning entrepreneur Dr Isabel Alvarez Martos.

Keywords: nanocellulose,biopolymer,bioeconomy,biochemistry,circular economy,microbial biotechnology,industrial microbiology,nanomaterials,nanofibrils,nanotechnology,coating
AQUAtic INVAders: Early Detection, Control and Management (AQUAINVAD-ED)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,Italy,Spain,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-06-01
End date: 2019-05-31
Duration (months): 48.0
Total project cost (EUR): 2079605.16
EU funding (EUR): 2079605.1600000001
Participants: 7
Project status: CLOSED

Aquatic Invasive Species (AIS) are on the rise due to the synergistic effects of climate change and habitat destruction. The impacts of AIS on Biodiversity, human health, and loss of ecosystem services are well known, but their control and management has now become a worldwide priority. Successful management of AIS is challenging because it requires several steps in succession: (1) early detection, (2) identification of routes of introduction and pathways of dispersal, and (3) development of efficient control measures. However, public awareness and stakeholder involvement are also critical .The main research goal of AQUAINVAD-ED is to exploit novel molecular advances combined with the power of citizen science to develop innovative methods of early detection, control and management of AIS. This will be achieved via a multi-disciplinary network of experts in invasion biology, aquatic biotechnology, citizen science and environmental policy working from 3 different countries. The inter-sectoral dimension of the consortium consists of fundamental and applied scientists from 3 universities, 1 technological institute, 2 government agencies, 1 NGO and 5 SMEs. AQUAINVAD-ED will catalyse research and commercial activity in the detection and management of AIS, as well as in the implementation of codes of good practice for the European industry and Government agencies. This will be achieved by training the next generation of researchers on the principles of invasion biology, providing them with the skills necessary to detect and quantify the ecological and socio-economic impacts of AIS and the ability to communicate science to the general public. The training program will be delivered through individual research projects, active participation in network activities and a unique combination of specialised courses, designed to increase employability in the consultancy sector, government, academia, and the water industry.

Keywords: biological invasions,environmental dna,metabarcoding,citizen science,crowd data sourcing,impact and risk assessment of invasive species
Transnational Figurations of Displacement: Connectivity and Mobility as Solutions to Protracted Refugee Situations (TRAFIG)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Research and Innovation actions
Countries involved: Austria,Ethiopia,Austria,Italy,Germany,Tanzania, United Republic of,Greece,Jordan,Norway,Netherlands,Pakistan,United Kingdom
Call: Addressing the challenge of forced displacement (H2020-SC6-MIGRATION-2018, 2018)
Start date: 2019-01-01
End date: 2022-06-30
Duration (months): 42.0
Total project cost (EUR): 3098426.25
EU funding (EUR): 3098426.25
Participants: 12
Project status: CLOSED

TRAFIG introduces a novel perspective on protracted displacement situations (PDS) that will improve the protection and resilience of refugees and enhance trust and cooperation between refugees and host communities. It considers the transnational and local connectivity of displaced people and host communities as well as their capability of mobility as socioeconomic and socio-psychological resources that displaced people use and upon which their resilience relies. The project will develop a rapid assessment tool to identify the most vulnerable groups in PDS and to analyse interactions between displaced and host communities. As an evidence-based tool for creating impact, it will support policymakers and practitioners to enhance the self-reliance of displaced people as well as host-refugees relations through tailored programming and policy development. We closely cooperate with key stakeholders throughout the entire life cycle of the project. Our research is based on a novel concept of transnational figurations of displacement that combines the figuration model – a meso-level approach emphasizing the networks of interdependent human beings – with the transnationalism approach and state-of-the-art knowledge on forced displacement. Through comparative empirical research, both qualitative and quantitative, in camps and urban settings at sites in Asia, Africa, and Europe, TRAFIG will answer the following questions: (1) How do displaced people gain access to and make use of humanitarian and migration policies and programmes? (2) Why and how do displaced people live in vulnerable situations and sustain their livelihoods? How can policy support their self-reliance? (3) How do transnational networks shape refugees’ experiences and trajectories? (4) Which processes structure relations between displaced people and host communities? (5) What are the medium and long-term economic impacts of PDS?

Keywords: protracted displacement situations,protracted refugee situations prs,humanitarian and migration policy,inter group relations,transnational networks,self reliance,resilience,multi sited research
An integrated biorefinery for the conversion of dairy side streams to high value bio-based chemicals (AgriChemWhey)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Public-private partnerships
Destination: Bio-based Industries
Action type: Innovation actions
Partnership: BBI (Art-187)
Countries involved: Ireland,Ireland,Austria,Germany,Ireland,Ireland,Belgium,Belgium,Belgium,Belgium,United Kingdom
Call: Valorisation of by-products or waste-streams from the food processing industry into high added-value products for market applications (H2020-BBI-JTI-2016, 2016)
Start date: 2018-01-01
End date: 2027-04-30
Duration (months): 112.0
Total project cost (EUR): 29949323.0
EU funding (EUR): 22007931.380000003
Participants: 14
Project status: SUSPENDED

Whey Permeate (WP) and De-lactosed Whey Permeate (DLP) are major side-streams of dairy processing and represent a key challenge for the dairy industry due to a lack of reliability in current disposal routes and represent a sustainability bottleneck for the expansion of milk production in Europe in the “post-milk-quota era”. AgriChemWhey will build a first-of-a-kind, industrial-scale biorefinery with integrated symbiotic industrial and agricultural value chains that will valorise over 25,000 tonnes (100% dry matter) per annum of excess WP and DLP to several added value products for growing global markets including lactic acid, polylactic acid, minerals for human nutrition and bio-based fertilisers. This will be achieved through a coordinated investment process and development path to realise the Flagship plant, representing the first major industrial venture to convert residues from food processing, as second generation feedstocks, to value added bio-based products. The Flagship will prove the techno-economic viability of the innovative WP/DLP-to-lactic acid biorefinery technology and will establish a new value chain for industrial symbiosis with other local actors for the production of high value sustainable food and feed (including high quality mushrooms) products from other side streams, as an enhanced circular bioeconomy approach to agriculture and agri-food waste. This offers society and industry the opportunity for greater resource efficiency - less food waste, more products from the same starting material (milk), and integration of food and non-food material production. AgriChemWhey will also develop a blueprint of an economic sustainability concept and replication plans for other regions across Europe, thus maximising both short and long term impacts, contributing towards the development of the European bioeconomy to promote rural growth, competitiveness and job creation, and aligning with European sustainability targets.

Keywords: bioeconomy,milk,circular economy,industrial symbiosis
Advanced MEMBranes and membrane assisted procEsses for pre- and post- combustion CO2 captuRe (MEMBER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Innovation actions
Countries involved: Spain,Spain,Italy,Spain,Germany,Spain,Norway,Switzerland,France,France,France,Netherlands,Netherlands,Netherlands,United Kingdom,Portugal
Call: High-performance materials for optimizing carbon dioxide capture (H2020-NMBP-2017-two-stage, 2017)
Start date: 2018-01-01
End date: 2022-06-30
Duration (months): 54.0
Total project cost (EUR): 9672418.0
EU funding (EUR): 7918901.0
Participants: 22
Project status: CLOSED

The key objective of the MEMBER project is the scale-up and manufacturing of advanced materials (membranes and Sorbents) and their demonstration at TRL6 in novel membrane based technologies that outperform current technology for pre- and post-combustion CO2 capture in power plants as well as H2 generation with integrated CO2 capture. Two different strategies will be followed and demonstrated at three different end users facilities to achieve CO2 separation: - A combination of Mixed Matrix Membranes (MMM) for pre- and post-combustion, - A combination of metallic membranes and sorbents into an advanced Membrane Assisted Sorption Enhanced Reforming (MA-SER) process for pure H2 production with integrated CO2 capture In both cases, a significant decrease of the total cost of CO2 capture will be achieved. MEMBER targets CO2 capture technologies that separate >90% CO2 at a cost below 40€/ton for post combustion and below 30€/ton for pre-combustion and H2 production. To achieve this objective, MEMBER has been built on the basis of the best materials and technologies developed in three former FP7 projects, ASCENT, M4CO2 and FluidCELL. In particular, special attention will be paid to the manufacturing processes scale up of key materials and products such as Metal Organic Frameworks (MOFs), polymers, membranes and sorbents. At the end of the project we will deliver a robust demonstration of the new materials at real conditions (TRL 6) by designing, building, operating and validating three prototype systems tested at industrial relevant conditions: - Prototype A targeted for pre-combustion in a gasification power plant using MMM at the facilities of CENER (BIO-CCS). - Prototype B targeted for post-combustion in power plants using MMM at the facilities of GALP. - Prototype C targeted for pure hydrogen production with integrated CO2 capture using (MA-SER) at the facilities of IFE-HyNor

Keywords: metal organic framework,mixed matrix membrane,palladium membrane,co2 sorbent,membrane assisted sorption enhanced reforming,advanced materials manufacturing,cost efficient pre,post combustion cap
Christian Illustrious Men: Christian Culture and Identity from Eusebius of Caesarea to Isidore of Sevilla (ChrisVirIll)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-11-01
End date: 2023-10-31
Duration (months): 24.0
Total project cost (EUR): 178320.0
EU funding (EUR): 178320.0
Participants: 1
Project status: SIGNED

This project aims to provide a multi-focal, trans-historical and trans-local analysis of the late antique Christian De viris illustribus (=DVI). It will demonstrate, against past analyses which have considered them as inert, timeless literary traditions, that the DVIs are deeply anchored into specific social, religious and historical contexts that they actively contributed to shape. ChrisVirIll will therefore shed new light on the impact of late antique literature on Christian identity and society. While the reception of these DVIs has been studied in quite some detail due to their success from the Middle-Ages on, their original purpose, context and meaning have received little attention. Yet, their success and impact on later periods cannot be fully grasped without a more comprehensive understanding of their initial production. This innovative project aims to fill this gap by offering answers on why and how, from the Constantinian turn, Christian authors appropriated the genre of the DVI, and how, from the time of Theodosius, through multiple continuations, they were developed to eventually reach "canonization" in later centuries. It will specifically focus on how this literary form was exploited to dynamically respond to new societal challenges and how they impacted the Christians' cultural identity. Providing a comprehensive, comparative and interdisciplinary analysis of these writings, this project will combine traditional philological-historical close-reading with insights from social and cultural studies (including gender studies). I believe that, thanks to this fellowship, my expertise in the history and literature of this period will help me reach my ambition of re-embarking on an academic career.
Revivable freezing solution for the insect farming market (FreezeM)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Insects are a promising source for sustainable, alternative protein for the now struggling animal feed industry, vital to ensuring the wellbeing of a growing human population. But in order to make a true impact and replace existing components in animal feed, insects have to be produced at an industrial scale, all year long, and in a stable manner. With its proprietary revivable insect egg freezing method, FreezeM creates the only viable way to generate a steady output of larvae to insect protein factories worldwide, enabling them to create for the first-time stocks of ready-to-use insect eggs - a solution corresponding to the agriculture seed production. FreezeM aims to revolutionize the insect farming supply chain, to become the leading manufacturer of eggs to this emerging industry, and to scale the business to €27 million by 2023. FreezeM was established in November 2017 as a spin-off from the Weizmann Institute of Science (WIS) in Israel. The three founders - all graduates of WIS - have vast experience in molecular genetics and developmental biology, especially working with fly embryos, each of them coming from an H2020 ERC funded lab. The founders participated in the first cycle of WISe - the WIS accelerator, receiving a license agreement for the technology and a seed investment from Yeda, the technology transfer arm of the WIS. The company filed a provisional patent application for its core technology. FreezeM participated in the ClimateLaunchPad competition and won 1st place in the Israel national finals, and the "Sustainable land use" award in the international finals. FreezeM is also taking part in the Green Pitch workshop - a green entrepreneurship workshop as part of the SwitchMed program (funded by the EU and UN). Until now, FreezeM has raised equity capital of $575K, of which $300K are secured and the rest is conditional. This is an improved resubmission of the H2020 Ph I proposal 854424 that received EC Seal of Excellence.

Keywords: animal and dairy science,supply chain management,secure food chain and wealth products,genetics and heredity,distribution and logistics,environment,pollution and climate
Super-Pixels: Redefining the way we sense the world. (Super-Pixels)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Austria,Italy,Germany,Czechia,United Kingdom
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2018)
Start date: 2019-03-01
End date: 2023-02-28
Duration (months): 48.0
Total project cost (EUR): 2479003.75
EU funding (EUR): 2479003.75
Participants: 5
Project status: CLOSED

We observe the world around us predominantly through the measurement of optical intensity. Although powerful, this leaves the other fundamental optical degrees of freedom, phase and polarisation massively under-utilized. Our tendency to solely use intensity results from the static sensor technology that is available, which offer very limited ability to dynamically reconfigure their function or perform any optical processing. In Super-Pixels we will co-develop a new integrated sensor platform that will revolutionize the way we process light to allow the full utilization of its fundamental properties. Redefining the core functionality of our sensor technology will radically impact the technology that is deployed in a broad spectrum of cross-disciplinary areas such as nano-particle detection, compact atmospheric corrected imaging systems, endoscopy, coherent communications and on-chip processing of structured light. This vision will be enabled by a compact and multi-functional photonic integrated chip that would be installed into phones, microscopes, cameras, communication and environmental monitoring systems, becoming central part of the way we collect and process optical information. In Super-pixels, we will create such an integrated photonics device that is based on a mesh of several hundred Mach-Zehnder interferometers, which will be used to dynamically map phase and polarization, with the ability to fully transform any optical field incident. A revolutionary prototype system will be delivered that will partner our Super-Pixels chip with a commercially available camera to enhance its functionality within a single frame of a camera. This prototype will support a number of potential applications that include visualising normally invisible nano-particles through phase mapping, imaging through multimode optical fibres, reconfigurable quantum communication links and mapping of airflow and particulates through phase and polarisation retrieval.

Keywords: integrated photonics,structured light,orbital angular momentum,optical control,atmospheric turbulence correction