Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
EURAXESS for Industry (EURAXIND)

Framework: Horizon 2020 — Science with and for Society
Programme: Make scientific and technological careers attractive to young students, and forster sustainable interaction between schools, research institutions, industry and civil society organisations
Action type: Coordination and support actions
Countries involved: Austria,Spain,Israel,Bulgaria,Hungary,Netherlands,United Kingdom
Call: EURAXESS outreach to Industry (H2020-SEAC-2015-1, 2015)
Start date: 2016-05-01
End date: 2018-04-30
Duration (months): 24.0
Total project cost (EUR): 814737.5
EU funding (EUR): 812237.5
Participants: 7
Project status: CLOSED

The EURAXIND project is led by CRAC-VITAE with 6 partners (all Bridgehead Organisations) and 7 Third Parties from across Europe. EURAXIND addresses 2 key ERA priorities (1) creating ‘an open labour market for researchers’ and (2) ‘the optimal circulation of, access to, and transfer of scientific knowledge’, by increasing employer engagement with the EURAXESS network and Career Development Centres. It will do this by: identifying researchers and employers needs to support intersectoral mobility and collaboration; providing targeted online tools and resources to support institutional outreach and engagement with employers; creation of an Industry Career Development Module to encourage researchers within academia to consider research careers in other sectors; and increasing industry participation in EURAXESS services (particularly the jobs portal), by developing a targeted Employer Engagement Toolkit for EURAXESS Service Centres. The objectives of the project will be pursued over a 24 month period. Core activities will include employer, researcher and institutional literature reviews and surveys to identify various stakeholder needs; development of an industry engagement strategy and 14 dissemination workshops for employers (7) and institutions (7). These will feed into the development of the two principal outcomes: the Employer Engagement Toolkit and Industry Career Development Module. All these activities build on relevant current and previous European projects including EURAXESS Top I, II , III, REFLEX and PIPERS. EURAXIND focuses on enabling partner organisations, and the EURAXESS network more generally, to engage more with business, provide opportunities for collaborations and build strategic partnerships. It will promote the recruitment of highly skilled researchers who can engage with businesses, and are able to promote their skills to them. In this way EURAXIND will make a long term contribution to ERA priorities and Europe's economic prosperity.

Keywords: euraxess service network,researcher career development,intersectoral mobility,intersectoral research collaboration,outreach to industry,open labour market,job opportunities,employer engagement
AstroChemical Origins (ACO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain,Italy,Italy,Italy,Italy,France,France,France,United Kingdom,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2018, 2018)
Start date: 2019-05-01
End date: 2023-10-31
Duration (months): 54.0
Total project cost (EUR): 4138452.54
EU funding (EUR): 4138452.54
Participants: 15
Project status: SIGNED

The project ACO (AstroChemical Origins) has two main objectives: 1) to unveil the early history of the Solar System, using the chemical composition of today forming Solar-like planetary systems and comparing it with that of the Solar System primitive bodies; 2) to train a new generation of researchers able to tackle this highly interdisciplinary problem, providing them with a wide-range of transferable skills, including the ability to communicate Science to a large audience. This will be obtained by setting up: (a) a coordinated network of PhD research projects which will be carried out by 17 ESRs under the supervision of members of the ACO Beneficiaries; (b) a structured secondment network, to expose ESRs to alternative research environments; (c) a significant exposure of ESRs to the non-academic sector, via PhD co-supervision, secondment, short visits and training from non-academic ACO Beneficiaries and Partners; (d) specific courses at the host institutions as well as network schools with specialized interdisciplinary and transferable skills courses; (e) international conferences open to the scientific community; (f) several activities to make ACO network and its science known to the general public. In order to achieve the ACO objectives, the proposed network is constituted by fourteen Beneficiaries, whose four from the non-academic sector, plus seven Partner Organisations, whose six from the non-academic sector. Each Participating Organization will provide a complementary expertise indispensable to achieve of the ACO objectives: (i) instrumental, observational, theoretical, computational, modeling, and experimental to reach the scientific goal and, (ii) on informatics, scientific presentation and management, for completing the wide-transferable training.

Keywords: astrochemistry,solar system early history
Strong Axioms of Infinity: Frameworks, Interactions and Applications (SAIFIA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-08-01
End date: 2022-07-31
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: CLOSED

In spite of their central role in modern set theory, strong axioms of infinity (or large cardinal axioms) are still surrounded by an aura of vagueness, a lack of generality and many open conceptual questions. After the study of large cardinals has evolved for over eighty years, recent results suggest that it now makes sense to develop a general theory of strong axioms of infinity in which all known large cardinals are seen as milestones in a hierarchy of mathematical principles derived from some much more general considerations about the reflective properties of the set-theoretic universe. The development of such a theory would lead to a breakthrough in our understanding of large cardinals and their role in mathematics, and provide strong justifications for their acceptance as true mathematical statements. In this project, we want to work towards this breakthrough with the help of novel combinations of concepts and techniques from different areas of set theory. We will develop general frameworks for strong axioms of infinity that incorporate all types of large cardinals studied so far. The work of the proposed supervisor on structural reflection properties and recent pioneering results in combinatorial set theory will serve as the starting points for this work. Moreover, motivated by the strong influence of large cardinals on the theory of definable sets of real numbers, we will study the impact of these axioms on definability at higher cardinalities. This task is closely related to one of the most important developments in modern set theory, Hugh Woodin’s programme of constructing a canonical inner model containing a supercompact cardinal. Finally, strong axioms of infinity have recently been used with great success to answer questions in other branches of mathematics, like category theory or homotopy theory. These results opened up a wide area of possible applications of set-theoretic results that we also want to explore in our project.

Keywords: large cardinal axioms,principles of structural reflection,combinatorial set theory,definability,applications of set theory
Single layer N-doped Graphene modified polymer Electrolyte Membrane with aligned nanowire electrodes for Direct Ethanol Fuel Cells (GemDEFC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-10-11
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

Direct ethanol fuel cells (DEFCs), benefiting from low operating temperature, environment-friendly operation, simplicity, quick start-up and shutdown, have been demonstrated as sources of portable and backup power in consumer electronic devices. If bio-ethanol, as the most used bio-fuel world-wide with an existing supply chain and infrastructure, is used, the carbon emission from DEFCs can be considered as zero. These advantages make the DEFC a potential alternative to existing technologies to fill the increasing gap between energy demand and energy storage capacity in the low power applications. However, the power performance of DEFCs is low, mainly limited by ethanol crossover through polymer electrolyte membrane (PEM) and the slow kinetic activity of ethanol oxidation reaction (EOR) at the anode. Thick membranes required to reduce the ethanol crossover but significantly increasing proton conducting resistance. A very high catalyst loading also needed at both electrodes to overcome the sluggish EOR and compensate the poisoning of the crossed ethanol. Challenges for DEFCs include reducing Pt loading and ethanol crossover to increase energy and power density, improve reliability and reduce cost. In GemDEFC, inspired by the unique proton conductivity and high impermeability to molecules of single layer graphene, the excellent mass transfer performance and catalytic activities of aligned 1D nanostructure electrodes, we’ll develop low ethanol crossover and highly proton conductive PEM modified with single layer N-doped graphene on the surface, and further hybrid with aligned Pt alloy or even platinum group metal–free (PGM-free) ZnS nanowire catalyst electrodes to achieve low-cost, high power performance and reliable DEFCs that can meet the targets for commercial applications in the low power applications. GemDEFC is built on the complementary skills of the Experienced Researcher (graphene and surface modification) and supervisors (1D nanostructures and fuel cells).

Keywords: direct ethanol fuel cell,electrode,graphene,ethanol crossover,nanowire,plasma,surface modification
Engineering kidney organoids to study the interplay between Tissue Mechanics and Metabolism: from development to disease (ENGINORG)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Spain
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-10-01
End date: 2026-09-30
Duration (months): 60.0
Total project cost (EUR): 1999937.0
EU funding (EUR): 1999937.0
Participants: 1
Project status: SIGNED

Research with human pluripotent stem cells (hPSCs) has led to the development of miniorgan-like structures in culture, so called organoids. Generally, organoids are generated exploiting cell-autonomous responses of hPSCs with minimal control over the external inputs supplied to the system. The unrestrained nature of these approaches explains, in part, key shortcomings of the organoid technology, such as limited capacity to recreate all cell types within an organ, maturation and function. Data from my laboratory has shown, for the first time, that the presentation of a physical instruction (elastic modulus-stiffness) during the derivation of hPSCs-kidney progenitor cells results in the generation of hPSCs-kidney organoids with higher differentiation potential and functional attributes. Similarly, our preliminary results show that boosting metabolic activities differentially regulated upon the presentation of controlled physical cues represents a new strategy to generate specific kidney cells on demand. ENGINORG proposes conceptual and technical advances to mechanistically link how the presentation of controlled physical and metabolic constrains during organoid generation are integrated and resolved through gene expression regulation and epigenetics. To this end, we will combine micropatterning techniques, hPSCs-genome engineering, metabolomics, biomaterials design and microfluidics. The identification of the molecular mechanisms connecting how metabolic and mechanical cues modulate cell fate and function will define minimal design principles for the proper control of cell-cell and cell-matrix interplay, and cell organization for organoid generation. This knowledge will be implemented through three interconnected objectives to understand and model early steps of kidney morphogenesis and Congenital anomalies of the kidney and the urinary tract (CAKUT), which account for ~50% of the etiology of chronic kidney disease in children worldwide.

Keywords: human pluripotent stem cells,organoids
A Customizable Robot to Include Children with Autism Spectrum Disorder (HOOKIE)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: SME instrument
Countries involved: Spain,Netherlands
Call: Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-01-01
End date: 2017-05-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

Nowadays, more than 1% of the children below the age of 14 are diagnosed with Autism Spectrum Disorder (ASD), which is a group of developmental disabilities characterized by impairments in social interaction/communication. The social and financial cost of this disorder are enormous, both for the families and for the national health systems. Most of the costs are related to special education and this hinders the inclusion in the society of children with ASD, whose talent is often squandered. Recent studies have proved that robotics can play a crucial role in this domain: robots are perceived by children with autism as being more predictable less complicated and threatening than humans. In the last few years, several robots have been launched to the market as educational and social aids; yet, no existing solution is affordable for families and provides enough flexibility to be tailored to the needs of a specific child. Hookie – the robot described in this proposal – fills exactly this niche, being customizable and affordable. Hookie is 3D printed (and hence families can create it together with their children) and based on a standard user interface, such as a smartphone. The system is at TRL 7: two iterations of design-trials have already been performed with specialised hospitals, and the results are very encouraging. It is now time to perform the business activities around the technology. This proposal describes the objectives of a feasibility study aimed at launching Hookie in nine EU markets (four in a first phase and other five later on). Upon the successful completion of the feasibility study, we will seek additional funds via different sources (including the SME phase 2 scheme) to take the product up to TRL 9 and eventually to full commercialization.

Keywords: autism spectrum disorder,robotics
Transport System with Artificial Intelligence for Safety and Fare Evasion (TRAINSFARE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Spain
Call: Small business innovation research for Transport (H2020-SMEINST-1-2014, 2014)
Start date: 2015-01-01
End date: 2015-05-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Our project’s main objective is to develop a decentralized, interoperable and flexible system to reduce some operational problems at mass transport systems and to increase their safety. One of the concerns of Mass Transportation Operators (MTO) worldwide is the significant amount of users that avoid paying (fare dodging), amount that is increasing nowadays (estimated value of €600 million/year). In the case of rail and metro, the installation of mechanical fare gates activated with magnetic cards helps reducing fare dodging but some users take advantage of the gate closing delay (necessary for safety reasons) and pass right behind the previous user, without validating any ticket whatsoever (tailgating). There is currently no effective solution for this problem except permanent human surveillance at the gates or the frequent deployment of mass controls: a group of inspectors checks every passing user. These mass controls are cumbersome, inconvenient for the paying user and easily avoidable by the fare dodger. HAL has developed an artificial vision system that automatically detects tailgating and allows the selective interception of the suspected wrong-doer even before they reach the platform. The system is being developed in collaboration with a globally respected MTO active in Barcelona, FGC (Ferrocarrils de la Generalitat de Catalunya), within their Smart Train program. A pilot under regular operating environment has proven the effectiveness of the system. With this proposal, we plan to elaborate a detailed feasibility study (Phase 1) that will possibly recommend to opt for Phase 2 funding later on, necessary for extended R&D and for a rapid worldwide dissemination of our solution. We expect to further expand our artificial vision technology (combined with mobile technology, when convenient) to solve other safety and maintenance challenges in nowadays mass transport operations. A second natural step could well be railway signal detection and monitoring.

Keywords: artificial vision,artificial intelligence,fare dodging,fare evasion,mobile technology
Asymmetric cooperative catalysts constructed on supramolecular helices (SupraCopCat)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-08-01
End date: 2020-09-30
Duration (months): 24.0
Total project cost (EUR): 185076.0
EU funding (EUR): 185076.0
Participants: 1
Project status: CLOSED

Novel robust catalysts are key to improve the efficiency and reduce the environmental impact of industrial processes, which provide crucial chemical intermediates/products in modern society. Catalysts development is traditionally a time-consuming step because it requires synthesizing and testing a large number of systems. Supramolecular catalysis can help suppress this bottleneck because it implies simple mixing of components from an existing library. In this project, we will merge the frontier concepts of supramolecular catalysis and cooperative catalysis aiming at developing efficient supramolecular cooperative catalysts. In this concept, two different catalytic units will be connected onto a supramolecular polymeric helix, so that they will work cooperatively to promote enantioselective Michael addition and asymmetric hydroformylation with good activity and excellent selectivity. Advantages compared to classical covalent catalysts will be: i) the possibility to easily tune the structure of the catalysts (e.g. the distances between the catalytic centers) by changing the nature of the building blocks, ii) the control of the configuration by changing the handedness of the helices, iii) the possibility to use chirality amplification effects. This research programme is set to be undertaken at the world-class research institution, Université Pierre et Marie Curie, with an excellent reputation and infrastructure. Through collaborating with host, the candidate will acquire a number of technical and transferable knowledge (i.e. a new research field, leadership skills). The ground-breaking results achieved in this project will be patented and then disseminated by different effective channels (i.e. publications, conferences, web resources), which will not only establish a new career perspective for the candidate, but will also further advance Europe’s capacity for innovation.

Keywords: supramolecular catalysis,supramolecular cooperative catalyst,asymmetric catalysis,supramolecular polymer,chiral helice,enantioselective michael addition,asymmetric hydroformylation
TETHIS-SBS-CTC: An innovative diagnostic testing platform to identify and characterize circulating tumour cells (CTCs) in blood samples. (TETHIS-SBS-CTC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-05-01
End date: 2018-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Cancer is one of the most important causes of death worldwide, accounting for 8.8 million deaths. The rate of new cases is expected to rise by 70% in the next 2 decades, posing a huge challenge for the healthcare system. If diagnosed early and treated adequately, many cases would have a high chance of cure. This realization is driving the growth in the cancer diagnostics market. The detection and analysis of Circulating Tumour Cells (CTCs) encloses a huge potential for real-time monitoring of cancer cases. CTCs are considered a “diagnostic tumour marker” since they are the reflection of a metastatic aggression. We at TETHIS have developed a new diagnostic platform to characterize CTCs from liquid biopsy (i.e. blood). The combination of our expertise in nanotechnology and strong biology knowledge have led to the development of a Smart BioSurface (SBS) that creates a perfect environment to immobilize CTCs using a total capture approach. Compared to the state-of-the-art alternatives, our methodology does not require pre-enrichment or selection. Having validated this technology for cancer diagnostics at the pilot stage, this project is conceived to finalise the development and market preparation of this technology, culminating in a diagnostic platform for cellular, proteomic and molecular characterization of CTCs. The platform will have key applications, including diagnostics and monitoring in clinical settings, and drug discovery & therapy development in the pharma/biotech sectors. The Phase 1 of this project is dedicated to run a Feasibility Study that helps us evaluate the project from a technical, commercial and financial standpoint. Once the project is finished, we expect our platform to improve the diagnostic capability in the oncology sector, enabling earlier detection and better management. In turn, it will secure the growth for TETHIS, expecting to gain over €10 million in profits, hire 15 new people and reach a ROI of €2.58 from this project after 5 years.

Keywords: circulating cancer cells,cancer characterization,targeted therapy,oncology diagnostics,cancer cell adhesion