Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Urban Adaptation and Alert Solutions for a TIMEly (re)Action (RETIME)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Efficient, sustainable and inclusive energy use
Action type: Innovation actions
Partnership: B4P (co-programmed)
Countries involved: Portugal,Slovakia,Denmark,Luxembourg,Italy,Spain,Germany,Estonia
Call: Solutions for the identification of vulnerable buildings and people-centric built environment, and for improving their resilience in disruptive events and altered conditions in a changing climate (Built4People Partnership) (HORIZON-CL5-2023-D4-02, 2023)
Start date: 2024-05-01
End date: 2028-04-30
Duration (months): 48.0
Total project cost (EUR): 5475761.25
EU funding (EUR): 4997269.88
Participants: 18
Project status: SIGNED

Natural and human-caused disasters, including uncontrolled urbanization pose multiple short-term and long-term risks, such as building inhabitants being vulnerable to heat or cold waves, older people or other vulnerable individuals struggling to reach safe places during emergencies, and citizens not receiving timely alerts from public authorities regarding impending flash floods, or firestorms, among others. The RETIME project aims to address impactful changes at both the contextual district level and individual homes. It will introduce a data-driven tool that aggregates existing data from weather stations, sensor networks, and satellite images, automated on-site surveys to simulate the impacts of current phenomena and future projections. The innovative aspect lies in an advanced computational analysis that generates prospective scenarios based on socio-architectural and environmental studies, combined with local, territorial remote and on-site surveys. RETIME will develop a suite of 4 innovative adaptation solutions for reducing risk in urban areas: 1) A sensor-based IT automated alert system; 2) A Digital Building Twin (DBT); 3) A digital Building Renovation Passport (BRP); 4) A Resilience Knowledge Hub and Decision Support platform. These tools will be sensitive and capable of prioritizing alerts based on the architectural and societal context-specific features in three pilot areas (in Portugal, Slovakia, and Estonia). RETIME will meet citizens' real-time needs while supporting control and decision-making processes by: identifying vulnerable groups and critical hotspots, enhancing building resilience; utilizing existing datasets and forecasting computational tools; delivering adaptation plans with a focus on carbon-neutral lifecycle awareness; and increasing citizens' understanding of natural disasters and their multi-scale impacts. Overall, RETIME strives to create a more resilient, informed, and prepared urban environment for all citizens.

Keywords: multi actor engagement vulnerable groups climate resilient cities hazard mitigation measures digital solutions for buildings emergency protocols alert inclusive building support system
Scalable Hardware for Large-Scale Quantum Computing (SCALLOP)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Finland,Netherlands
Call: EIC Transition Open 2023 (HORIZON-EIC-2023-TRANSITION-01, 2023)
Start date: 2023-09-01
End date: 2026-02-28
Duration (months): 30.0
Total project cost (EUR): 2499998.75
EU funding (EUR): 2499998.75
Participants: 2
Project status: SIGNED

Computing power is key to innovation, allowing us to process vast amounts of data and solve complex problems in fields such as finance, healthcare, science and engineering. However, traditional computing has limitations, and quantum computing offers a solution. Quantum computers excel at optimization tasks such as solving complex logistical problems; one day, they may be able to accurately model viruses and drugs, as well as come up with climate solutions. However, we currently face hardware and scalability limitations in creating large-scale and fault-tolerant quantum computers. To address this challenge, we have developed a new technology that integrates a cryo-CMOS multiplexer for precise control of high-quality silicon spin qubits, as well as commercial-ready nanometer-scale CMOS processes to create and accommodate millions of such qubits. Our technology operates at relatively high temperatures, resulting in a smaller carbon footprint and more compact form factor. This will make it a practical and energy efficient solution for easy and sustainable deployment. Our goal is to build a full-stack quantum computer demonstrator using SQT's breakthrough high quality Si spin qubit & cryo-CMOS multiplexer technology and QBX's extensive gate model quantum computing characterization & control experience. The final demonstrator system will be a significant step forward in the development scalable, fault-tolerant quantum computers that require millions of qubits.

Keywords: quantum computing,quantum technology,silicon qubits,semiconductor technology
Robust control of the space debris population to define optimal policies and an economic revenue model for the sustainable development of space activities (GREEN SPECIES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Italy
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-07-01
End date: 2028-06-30
Duration (months): 60.0
Total project cost (EUR): 1999398.0
EU funding (EUR): 1999398.0
Participants: 1
Project status: SIGNED

Space assets offer services of social and economic benefit for the humankind and enable monitoring the condition of our planet. As recognised by the UN and space agencies, space missions for Earth observation, geolocation, telecommunication, science, and technology contribute to the achievement of the Sustainable Development Goals. As our lives become more and more interconnected thanks to satellites and space is more easily accessible, Space can be seen as the extension of our planet biosphere. As such, long-term sustainability of space activities will be possible only if a change of behaviour is put in place by space faring nations. The growth of space debris is following an exponential trend, which is typical of many other environmental stressors of Earth system trends. Immediate actions are needed to mitigate the increasing risk of collisions and enable the future use of Space as a common. In GREEN SPECIES project I will devise a new interdisciplinary framework for the modelling of the space debris population, and the forecast of its evolution. A probabilistic space debris model will be devised for the overall space debris environment. All uncertainties of physical, economic, and political nature will be modelled, and the forecast of future launch traffic and compliance to guidelines included via economic approaches and evidence theory. As unique feature, the project will incorporate the management of the debris environment through a robust time-delayed controller, applied to the space debris model, described as a complex dynamical system. Ideal feedback control actions will be transformed into policies and guidelines, via quantitative indicators, assessing both the environmental impact and the social and economic benefit of space missions. Policies will act as the actuator of a real controlled system. GREEN SPECIES will propose the first economic model for a revenue system for Sustainable Space by leveraging approaches from the management of the global climate.

Keywords: space debris modelling space debris mitigation space sustainability space traffic management space debris evolution space debris index space missions global development goals
Cross-linguistic influence in third language acquisition: Sentence processing and comprehension by child heritage bilinguals (TomRis)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-09-01
End date: 2025-10-31
Duration (months): 26.0
Total project cost (EUR): 226751.04
EU funding (EUR): 226751.04
Participants: 1
Project status: SIGNED

The project TomRis (Cross-linguistic influence in Third language acquisitiOn: Sentence processing and coMprehension by child heRItage bilingualS) advances our knowledge about the functioning of a child's multilingual brain and uncovers how a multilingual heritage speaker processes and comprehends a third language in real-time. TomRis is the first study to investigate how typological primacy and structural proximity between the involved languages affect cross-linguistic influence (CLI) in the processing and comprehension of a third language during reading sentences. The question is whether the (mis)matched properties in morpho-syntactic structures in the prior languages, which are typologically close (Norwegian/ Dutch) to or distant (Turkish) from English, facilitate the processing of L3 English sentences or not. TomRis offers a groundbreaking approach to capturing the traces of L1 and L2 in processing L3 English by focusing on the same heritage language (Turkish) in two different linguistic contexts (Norway/ the Netherlands). Also, it keeps the task constant in obtaining offline (grammaticality judgement) and online (eye-tracking) processing data during reading. A further novelty in TomRis is the focus on two distinct development stages of language learning to compare the degree and source of CLI in L3 English processing and comprehension at different stages of acquisition. Also, I will match the participants not only based on their proficiency in the L3 (thus isolating potential effects of CLI from previously acquired languages) but also based on their language proficiency in the background languages. Gaining a deep understanding of the factors that facilitate or interfere with CLI in multilingual children is a good investment for the further development of the field. The results will be crucial for all who have to deal with the challenges of multilingual children's language learning such as language educators, policymakers, language therapists, and parents.

Keywords: multilingualism,heritage language,cross linguistic influences,online processing,comprehension,turkish,norwegian,dutch,english,morpho syntax
Understanding metacommunity dynamics through plant-pollinator interactions in agroecosystems to improve the efficiency of agri-environmental schemes (METAGROLAND)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-01
End date: 2027-12-31
Duration (months): 24.0
Total project cost (EUR): 202125.12
EU funding (EUR): 202125.12
Participants: 1
Project status: SIGNED

Maintaining biodiversity in agricultural landscapes has become a pressing societal challenge. Species interactions contribute to critical agroecosystem functions such as pollination and pest control. However, scientific evidence suggests that the rate of loss of species interactions is even higher than the rate of species extinction. Agricultural policies promote agri-environmental schemes (AES) to halt biodiversity loss on farmland, but with varying degrees of success. For example, little is known about whether AES support the growth of wildlife populations, or whether they simply concentrate local populations while depleting surrounding areas. METAGROLAND project presents an innovative research agenda that pursues effective AES design at large scales by presenting a novel interdisciplinary framework: the study of plant-pollinator metacommunity dynamics in agricultural landscapes from a social-ecological perspective. This project will firstly investigate the ability of AES and other landscape elements to attract and maintain pollinator species across landscapes, thereby gaining a mechanistic understanding of sink-source dynamics in the metacommunity. Secondly, the metacommunity structure will be investigated by applying and improving a novel methodology: spatial meta-networks. This will allow the detection of landscape characteristics that promote metacommunity cohesion and stability by identifying those landscapes that act as spatial hubs for plant-pollinator interactions across space. Third, the impact of land managers' social networks on metacommunity dynamics will be assessed to provide guidelines for effective AES design based on the synthesis of ecological processes and social dynamics. Beyond new fundamental social-ecological knowledge of agricultural systems, the results of METAGROLAND will contribute to the advancement of biodiversity conservation and agroecological practices, ultimately promoting fair, healthy and environmentally sound food systems.

Keywords: pollinator,metacommunity,meta networks,social ecological systems,agricultural policy
Next Generation Immune Checkpoint Inhibitor for Cancer Therapy (ReTenTion)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-02-15
End date: 2028-02-14
Duration (months): 24.0
Total project cost (EUR): 216240.0
EU funding (EUR): 216240.0
Participants: 2
Project status: SIGNED

Immune checkpoint inhibitors (ICIs) for cancer therapy have revolutionized the treatment of several cancers. These ICIs are made from monoclonal antibodies that antagonize inhibitory signals via cytotoxic T-lymphocyte- associated antigen-4 (CTLA-4) and programmed cell death protein-1 (PD-1) that block the tumoricidal activity of T cells. Although these ICIs have improved the overall survival of cancer patients such as cutaneous melanoma patients, only one third of patients has remained progression-free 5 years after initiating ICI therapy. This low efficacy is largely due to (1) the presence of immune suppressive regulatory T cells (Treg) within tumor microenvironment (TME) (2) the lack of efficacy of tumor penetration and retention. To improve the current ICI, this project RenTenTion aims to develop a next generation ICIs with smaller molecule so called single domain antibody (sdAb), give rise to enhanced tumor penetration. Targeting against a new immune checkpoint molecule 41-BB that highly expressed by intratumoral Treg, this next generation sdAb based ICI will inhibit tumor promoting immune cells Treg, while stimulate tumor rejecting immune cells such as effector T cells in tumors. Additionally, this project will couple the sdAb with collagen binding domain receptor so called leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) that bind to collagen in the tumor, therefore sustain tumor retention. This project “ReTenTion” will fill a gap for a strong need for new ICI molecules capable of addressing immunosuppressive in TME, yet smaller than conventional ICIs, boosting passive delivery.

Keywords: immune checkpoint inhibitors,single domain antibody
Musicality in Animal Songs (MAS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 214344.72
EU funding (EUR): 214344.72
Participants: 1
Project status: SIGNED

Musicality can be defined as the biological and cognitive abilities necessary to appreciate and create music, which makes song production a significant marker of the trait in the human species. In analogy, some acoustic behaviours of other species, whether birds, whales or primates, have also been traditionally termed “songs”. However, to date the relatively few studies of parallels between human and animal songs have focused mainly on bird songs. Broader cross-species comparison of animal songs would contribute to addressing the evolutionary origins of music, by disentangling the role of phylogeny and behavioural traits hypothesised to underlie musicality in humans. Two exemplary mammalian singers are humpback whales and gibbons. Their tonal and patterned vocal sequences are traditionally termed songs, but features of musicality have not yet been rigorously assessed. Such an observation would provide critical insights, as these two species possess proposed fundamental traits of musicality (they both have harmonically rich vocalisations, humpback whales are vocal learners and gibbons sing in duets), and they lie at very distinct branches of the mammalian phylogenetic tree. This research will thus test the existence of musical features in humpback whale and gibbon songs. Tests for the presence of overtone-based pitch selection (i.e. frequency intervals corresponding to small-integer proportions drawn from the harmonic series) and expressiveness (i.e. the oscillation between repetition and variation found in human music) have been successful in bird songs. Systematic measurements for these two features will be conducted in passive acoustic recordings of wild singing humpback whales and gibbons, for their songs to be compared with human music. This search will benefit from machine learning based vocalisation detection, classification and similarity measurements, as well as sub-unit segmentation, allowing a systematic analysis of musicality, robust against both signals

Keywords: bioacoustics,biomusicology,musicality
Strengthening regional stem cells based research for advancement of multi modal innovative strategy for modelling neurodevelopmental disorders (STREAMLINE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Serbia,Netherlands,Greece,United Kingdom
Call: Twinning Western Balkans Special (HORIZON-WIDERA-2021-ACCESS-02, 2021)
Start date: 2022-07-01
End date: 2025-06-30
Duration (months): 36.0
Total project cost (EUR): 1162391.0
EU funding (EUR): 1162391.0
Participants: 4
Project status: CLOSED

Neurodevelopmental disorders (NDDs) caused by alterations in early brain development are a group of complex and heterogeneous disorders that give rise to the psychiatric conditions such as autism spectrum disorders, intellectual disability, schizophrenia and bipolar disorder. NDDs have a high socio-economic impact and patients with NDDs and mental health problems are geographically dispersed. Thus, establishment of high capacity regional centres with equivalent research capacity and codes of practice is needed in order to build global research activity. The goals of STREAMLINE are to enhanced strategic networking and reinforce research and innovation potential of the Institute of Molecular Genetics and Genetic Engineering (IMGGE) in order to develop IMGGE as a high capacity hub for research of NDDs in the Western Balkans which is able to integrate with similar centres in Europe. This will be achieved by twinning IMGGE with three top-class research institutions in Europe: Cardiff University, University of Maastricht and Centre for Research and Technology. The project objectives are: a) to enhance the current and scale up the overall strategic networking activities between the IMGGE and internationally-leading European partners and regional partners; b) to raise the research profile of research stuff and scientific attractiveness of IMGGE in the field of NDDs; c) to strengthens research management capacities and administrative skills of the IMGGE staff and d) to become a regional leader in innovations tackling NDDs. Objectives will be achieved through networking, staff exchanges, training, summer schools, symposia, workshops, participation at conferences and dissemination in scientific community, industries and public. Twinning with partners will provide access to new research avenues, creativity, development of new approaches and increased mobility (inwards and outwards) of qualified scientists.

Keywords: neurodevelopmental disorders 22q11 2ds ipscs neural differentiation brain organoids neuronal network electrophysiology transcriptomics in vitro drug screening whole genome sequencing
Emulation of Wireless Communication among Chiplets inside a Computing System (EWiC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2024-11-01
End date: 2026-04-30
Duration (months): 18.0
Total project cost (EUR): 165000.0
EU funding (EUR): 150000.0
Participants: 2
Project status: SIGNED

Domain specialisation (e.g., AI) coupled with skyrocketing manufacturing costs of chips led to a paradigm shift towards chiplet-based computing. However, the current Network-on-Package (NoP) is not suited for the increasing chiplet (CPUs, AI accelerators, etc) count and diverse communication needs. As a result, communication has become the main bottleneck to computing advances. Wireless transmission can enable one-hop communication with low latency parallelism. The wireless links can be reconfigured dynamically for demand-specific services. Finally, the native broadcast capability of wireless transmission will provide natural support for scalability. However wireless communication is limited by the bandwidth. Hence, the ERC Starting Grant WINC explored via simulation combining wireless communication with the high bandwidth of wired connections, proving potential for >5× speedups. In EWiC we aim, for the first time, to emulate and demonstrate wireless communication among chiplets inside a computing system. The goal is to experimentally validate our simulation results, which have shown high speedups in multi-chiplet systems. Successful results will generate interest in the industry for further research and application in various domains, such speeding up computation in pharma for new drug design. EWiC will thus help fully realise the trillion-euro potential of advanced computing, alongside immense social benefits, and establishing EU leadership in this field. The EWiC project will thus assess the commercialization potential of our technology, engaging with key stakeholders such as chipmakers and end-users. Exploitation options including licensing, startup creation, or joint ventures, will be explored based on prototyping results and market entry considerations. Our IPR strategy will involve a thorough analysis to identify and protect the novel results of the project. We will additionally carry out a Freedom to Operate (FTO) analysis to ensure exploitability.

Keywords: wireless interconnects emulation multi chip systems computer architecture