Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Effective Lifetime Extension in the Marine Environment for Tidal Energy (ELEMENT)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Research and Innovation actions
Countries involved: Germany,Belgium,Finland,Norway,France,France,France,France,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Developing solutions to reduce the cost and increase performance of renewable technologies (H2020-LC-SC3-2018-RES-TwoStages, 2018)
Start date: 2019-06-01
End date: 2023-05-31
Duration (months): 48.0
Total project cost (EUR): 4984622.5
EU funding (EUR): 4984622.5
Participants: 15
Project status: SIGNED

In the ELEMENT project, a partnership of world-leading academic, industrial and research organisations will develop and validate an innovative tidal turbine control system, using the tidal turbine itself as a sensor, to deliver a step change improvement in the performance of the tidal energy sector. By enhancing an existing tidal turbine controller and combining with a state-of-the-art control technology developed for wind turbines, the ELEMENT project will use behavioural modelling and artificial intelligence to optimise performance and deliver an adaptive control system that will slash the lifetime cost of energy by 17%, driving the EU tidal energy sector to commercial reality. The objective of the project are to: - Optimise the control system of a tidal turbine, using behavioural modelling to reduce predicted loads - Use improved understanding of turbine behaviour to maximise energy yield - Optimise tidal turbine design for world-leading improved performance and reduced cost - Develop and demonstrate adaptable control system technology with a wide range of application - Minimise environmental impacts by integrating environmental monitoring into the control system - Increased resistance to marine environment & extended lifetime of tidal turbines - Maximise shared learning between EU projects - Improve the knowledge base regarding impacts of tidal energy on local communities - Increase public support for tidal energy projects Activities will include: - Integrating state-of-the-art technology from the tidal and wind energy sectors - Demonstrating a prototype system using onshore bench-testing, tow testing, and in-sea deployment at two real tidal sites - Demonstration on subsea and floating devices, with geared and direct-drive drive trains - Environmental and socioeconomic assessment of tidal energy at a regional, national and EU level - Independent verification of project results - Knowledge Transfer via a targeted communication programme

Keywords: tidal energy,tidal power,ocean energy
INTEGRAL COST-EFFICIENT SYSTEM FOR SMART NAVIGATION OF THE VESSEL (JANUS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-02-01
End date: 2019-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Vessels of the future must undergo an important control of safety, loads, machinery, consumption, contamination, noise, etc, and this control should be possible from the ground. This means that it will be necessary to know accurately and at all times what is happening on the ship and, in turn, should have the possibility of intervening in it remotely. For this, the automation and integration of intelligent systems will be increasingly important. Based on this objective, Janus Systems has developed JANUS®, a system that combines software, hardware and sensors and that once installed on any existing vessel or under construction, makes it “Smart” and allows its management or governance (both in calm Waters and in adverse conditions) from a Remote Operation Centre via satellite. That is, a system that allows the existence of remote ships. The system consists of 8 modules that work together, integrating all aspects of safety, efficiency, environmental and navigation, according to the regulations that have already entered into force or will enter soon.

Keywords: smart navigation,maritime safety,vessel efficiency,secure navigation,remote control system,naval engineering
Trust in Governance and Regulation in Europe (TiGRE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Israel,Norway,Belgium,Poland,Switzerland,Netherlands,Denmark
Call: Trust in governance (H2020-SC6-GOVERNANCE-2019, 2019)
Start date: 2020-01-01
End date: 2023-09-30
Duration (months): 45.0
Total project cost (EUR): 2999810.0
EU funding (EUR): 2999810.0
Participants: 10
Project status: SIGNED

TiGRE provides an encompassing and coherent analytical framework for the study of trust relationships in governance. It studies trust among actors of regulatory regimes, such as regulators, political, administrative and judicial bodies, the regulated industries, service providers and their interest organisations, consumers and other societal interests, as well as citizens at large. TiGRE opens thereby new research directions within the tradition of studies of trust relationships between citizens and public authorities. TiGRE’s aim is to reveal the role of trust and distrust in European regulatory governance and the ways trust can be maintained, enhanced, repaired and nurtured via administrative practices and reforms. It takes a multilevel governance approach, which includes the EU level as well as the national and regional ones. Trust – both as a pre-condition and a consequence of well-functioning regulatory regimes – is a key factor to be considered in order to capture how these regimes are able to produce effective and legitimate governance. The in-depth investigation of the complex interplay between trust configurations and regulation in different regulatory regimes (finance, food safety, communication and data protection) across levels of governance and in several countries requires the joint effort of experts with wide-ranging experience. TiGRE is run by a tightly integrated multidisciplinary consortium of top-level scholars, who bring together a very broad range of theoretical, substantial, and methodological skills. A cutting-edge mixed-method approach is applied to provide a comprehensive understanding of such multi-faceted trust-related processes. To bridge research with policy and practice, TiGRE provides criteria, indicators and early warning mechanisms for detecting decreasing trust, and scenarios on consequences thereof. They will be validated through interaction with stakeholders and compared with evidence from outside the EU.

Keywords: multi level policymaking,european governance,regulation,trust and distrust,accountability,regulatory regimes
Colloidal Nanomaterials for Smart Applications (COMPASS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Italy,Belgium,Netherlands,United States
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2015, 2015)
Start date: 2016-03-01
End date: 2020-02-29
Duration (months): 48.0
Total project cost (EUR): 859500.0
EU funding (EUR): 859500.0
Participants: 7
Project status: CLOSED

The COMPASS project unites key players in Europe and the US with the aim to advance the field of colloidal nanocrystal (NC) synthesis and assembly and their exploitation in photonics, sensing, energy conversion and medicine. COMPASS aims to (i) develop colloidal NCs with desired properties by controlling their size, shape and composition, and to demonstrate routes allowing for large production volumes with nearly identical size and shape; (ii) develop approaches for NC self-assembly in ordered superlattices constituting NC solids with novel properties; (iii) understand the optoelectronic properties of novel NC-based materials by advanced optical and scanning probe spectroscopy methods, and explore pathways for their implementation in light emission, sensing, energy conversion and medicine; (iv) establish a consolidated network between leading EU and US institutes to provide a stimulating international environment for talented young researchers; (v) advance the level of R&D in Europe and the US and foster technology transfer and dissemination; (vii) raise the awareness of the general public on the prospects of NC materials in future technologies. Young scientists will be formed by "training by research" in long term stays at host labs and by lecture series held in the network that cover specific research topics, technology transfer and management/communication skills, leading to an interdisciplinary and international formation. The exchange will consolidate existing initial links between some of the lead scientists in COMPASS and establish a long lasting network that will have strong impact on science and education with significant repercussions in industry. The work plan is divided in 5 strongly linked workpackages that deal with Management, NC Fabrication, Self Assembly and Surface Functionalization, Photonics and Optoelectronics, and Energy Conversion. COMPASS will be guided by an executive board that consists of the coordinator and the lead PIs of the partners.

Keywords: cation exchange,upconverting nanoparticles,nanocrystals,nanowires,catalysis,biomedicine,energy conversion,superlattices,self assembly,optoelectronics,lasers,plasmonics
Towards clinical trials for a novel treatment for stroke (NOGOPROOF)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Switzerland
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-03-01
End date: 2018-08-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Stroke is the leading cause of adult disability and represents a major health problem in the EU and the Western world. Despite available acute care treatment and rehabilitation therapies, more than half of the patients remain disabled and there is a large unmet medical need accordingly. Regeneration of interrupted nerve fiber tracts and plastic “hardware” changes in the adult mammalian central nervous system are extremely restricted, a phenomenon which represents a key reason for the low degree of recovery following CNS injuries including stroke. The molecular impediments that form the basis of this phenomenon are neurite growth inhibitory proteins expressed in central nervous system myelin, in particular the membrane protein Nogo-A which was discovered by our group. Importantly, antibodies directed against Nogo-A have been shown to induce axonal regeneration, enhance plastic circuit rearrangements and mediate significant improvements in functional recovery in rodent and non-human primate models of stroke and spinal cord injury. As recently shown in the ERC advanced grant supported the project ‘Nogorise’, almost full functional recovery was observed in rats with large strokes when anti-Nogo-A antibody treatment was followed by intensive rehabilitative training. As currently no therapy for human stroke patients beyond acute care and rehabilitation exists, there is a substantial market opportunity for the anti- Nogo-A therapy. The proposed activities within the present project aim at further establishing preclinical proof-of-concept for an anti-Nogo-A administration paradigm translatable to human stroke patients and development of human antibodies targeting Nogo-A. The expected data package will allow the critical transition from preclinical to clinical development and support the development of a comprehensive business strategy.

Keywords: stroke,neural plasticity,regeneration,anti nogo a antibody therapy,preclinical proof of concept
Optimising big data from citizen science projects for biodiversity research (OptimCS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-11-01
End date: 2022-10-31
Duration (months): 24.0
Total project cost (EUR): 174806.4
EU funding (EUR): 174806.4
Participants: 1
Project status: CLOSED

Citizen science – research conducted in whole or in part by people for whom science is not their profession – is increasingly valuable for society, ecology, and conservation. Natural resource and landscape management based on the best available science is increasingly relying, at least in part, on citizen science data to make informed and adaptive decisions supporting biodiversity conservation . The data collection power of citizen science is enormous, but as citizen science at this scale is a new development in ecology and conservation, there is a great deal of inefficiency in this process. The largest inefficiency is that, to this point, the most ‘successful’ citizen science projects generally have a haphazard sampling regime replete with redundancies and gaps in the associated citizen science data. Can we direct this enormous amount of effort more efficiently? What steps can be taken at the upstream portion of citizen science projects to maximise efficiency of analyses with downstream datasets? This project will build a workflow which allows us to maximise the information content that citizen scientists contribute to our collective knowledge of biodiversity by developing algorithms that predict the highest ‘valued’ sites in time and space for biodiversity sampling by citizen scientists which leads to more efficiently directing effort in space and time.

Keywords: ecological modelling,species distribution models,citizen science,biodiversity,trend models,pareto frontier
Support for Enhancing Innovation Management in SME and Key Account Managementin Niedersachsen (N-SUPP_INNO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Germany,Germany
Call: INNOSUP (H2020-Adhoc-2014-20, 2014)
Start date: 2014-05-01
End date: 2014-12-31
Duration (months): 8.0
Total project cost (EUR): 54400.0
EU funding (EUR): 43520.0
Participants: 3
Project status: CLOSED

The general objective of this proposal is to offer services for SMEs that help increasing the efficiency and effectiveness of investments in research, development and innovation and by contributing to a better and more efficient connection to providers to more special support in this field of action. Partners will deliver these services in the NUTS-1 region Niedersachsen DE9 (Germany). To achieve the above mentioned objectives partners in this proposed consortium will: 1. Increase the efficiency and effectiveness of innovation processes in small and medium sized enterprises with significant innovation activities that could potentially become beneficiaries of European support programmes for research and innovation. This service, provided independently from a specific innovation project and focusing on a company's innovation management system, is called Enhancing the innovation management capacity of SMEs. All partners will provide this service. • Partners will deliver 14 Enhancing actions as described in Work package 1 as 7-day-packages The number of Enhancing action is justified by experience of partner NBank, which carries out 25 to 30 Innovation audits a year. Clients have to be found and also to be selected as suitable for the service. 2. Identify bottlenecks in the creation of economic impact in companies benefitting from grants under Horizon2020's SME instrument and address these bottlenecks with the help of capable coaches. • Partner NBank will deliver 2 Key Account Management actions as described in Work package 2 as 7-day-packages related to successful proposals for the SME Instrument from the region. The number is justified by the knowledge about how many successful proposals are expected on the SME-Instrument-Tool. Broken down to the region, NBank expects 1-2 cases for Lower Saxony. If the number of cases is higher, NBank will provide KAM service accordingly and lower the number of enhancing actions.

Keywords: innovation audit,sme instrument,innovation management key acount management
HYPERTRANS: Transport of hyperpolarized substrates for metabolic MR imaging (HYPERTRANS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2016-12-01
End date: 2018-05-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Dynamic metabolic imaging with hyperpolarized substrates is a new and unique non-invasive magnetic resonance imaging tool. It opens the window to metabolic aberrations at the heart of many diseases, and the ability to image these changes provides the opportunity to fundamentally improve clinical diagnosis and treatment follow-up. Our long-term ambition is to make hyperpolarized substrates for metabolic imaging with MRI available for every clinical institution. The short-term goal to be reached first, is to make the technique of dynamic metabolic imaging available to the wide scientific community. We will implement a concept in which we can polarize substrates at one central location and store these hyperpolarized substrates for transport and use in other academic institutions. This solution overcomes the current need for an on-site dynamic nuclear polarizer when performing preclinical metabolic imaging with MRI, allows an efficient use of resources, and enables scientific institutions to easily adopt this powerful emerging imaging tool. Once our proposed concept is proven, and in line with the existing infrastructure and legal license of our institution to manufacture, provide and transport radionuclide tracers to other hospitals, we propose to set up a spin-off company to manufacture, provide and transport hyperpolarized substrates to pre-clinical research institutions. We have currently contacted 11 pre-clinical research sites within transportation distance of our site, of whom 6 have already expressed serious interest in the possibilities of on-demand hyperpolarized substrates. When, in the long run, pre-clinical research has identified and validated the use of dynamic metabolic imaging for use in patients (e.g. in monitoring treatment response in oncology), this company can take the next step to provide hyperpolarized substrates to clinical institutions and general hospitals.

Keywords: transport of substrates,magnetic resonance spectroscopy,dynamic nuclear polarization,rapid melting
Metastasis-associated altered molecular patterns in the brain (ALTER-brain)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Spain
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-07-01
End date: 2025-06-30
Duration (months): 60.0
Total project cost (EUR): 1897437.0
EU funding (EUR): 1897437.0
Participants: 1
Project status: SIGNED

Organ colonization is the most inefficient step of metastasis. However, once a few cancer cells manage to re-initiate their growth in the brain, the initial naïve microenvironment, which was not favouring and even actively limiting the number of potential metastasis initiating cells, is slowly rewired into a different ecosystem with pro-metastatic properties. In this project (ALTER-brain), we will study the biology of microenvironment reprogramming to explore innovative ways of treating metastasis. Microenvironment reprogramming relies on altered molecular patterns that emerge in specific brain cell types simultaneously to the outgrowth of metastases. Dissecting the biology of these emerging patterns and their functional consequences could provide the basis to prevent metastasis but also to treat advances lesions. A key objective of ALTER-brain is the identification of newly established functional networks among previously non-connected components of the microenvironment that are critical to nurture tumour growth. This research proposal focuses on metastasis in the brain given its rising incidence, poor therapeutic options and short survival rates upon diagnosis. ALTER-brain will use novel (i.e. spontaneous metastasis) and clinically relevant (i.e. relapse after therapy) experimental mouse models of brain metastasis combined with genetically engineered mice in which we will target specific components of the microenvironment. In addition, we will apply novel lineage tracing technologies to understand the origin and emerging heterogeneity of the reprogrammed microenvironment. Given the clinical relevance of our research, human brain metastasis provided by our clinical network will be used to validate key findings. ALTER-brain will identify key principles underlying the unknown biology of the brain under a specific pathological pressure that might be translated to other highly prevalent disorders affecting this organ in the future.

Keywords: metastasis,microenvironment,brain,astrocytes,innate immune system,acquired immune system,experimental therapy,endothelial cells