Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Moduli spaces in low dimensions (ModuLow)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2027-01-01
End date: 2031-12-31
Duration (months): 60.0
Total project cost (EUR): 1356152.5
EU funding (EUR): 1356152.0
Participants: 1
Project status: SIGNED

The topological properties of low dimensional moduli spaces play a fundamental role across algebra, geometry, and topology. My research programme will build homotopical tools for moduli spaces of 3- and 4-manifolds, and moduli spaces of links in 3-manifolds, with my main applications being to manifold symmetries and configurations. The upgrading of discrete techniques for ‘an object’ to space-level techniques on ‘the moduli space of all such objects’ is a central theme. Moduli spaces of manifolds, or, equivalently, classifying spaces of manifold diffeomorphism groups, are foundational objects which classify smooth manifold bundles. The diffeomorphism group of a manifold—the group of symmetries—is a topological group which ought to be studied through a homotopical lens. My recent joint work solved a conjecture of Kontsevich on the homotopy type of moduli spaces of 3-manifolds. This breakthrough lays the groundwork for some of my goals: I will use it to compute rational cohomology rings of salient 3-manifold moduli spaces, yielding characteristic classes of 3-manifold bundles. Furthermore, I will classify the existence of sections for natural maps between 3-manifold and 4-manifold moduli spaces. The topological properties of moduli spaces of unparametrised links in 3-manifolds will play a central role: these can be viewed as configuration spaces of 1-manifolds in 3-manifolds. These spaces are yet to be thoroughly understood, and it is a fundamental problem to describe their homotopy type. I will prove a finiteness theorem, and develop a framework to compute motion groups of configurations of links in 3-manifolds. An underlying theme is homological stability, and I will show families of these spaces satisfy (higher) homological stability. One of my main aims is to combine my work on all three moduli spaces, by introducing an innovative method to represent families of 4-manifold diffeomorphisms via motions of Kirby diagrams (decorated links) in a 3-manifold.

Keywords: knots,links,3 manifolds,4 manifolds,homological stability,moduli spaces,classifying spaces
Scaling Up Biostimulant Technology for Agriculture Resilient to Climate change (SUBTARC)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2100000.0
EU funding (EUR): 2100000.0
Participants: 1
Project status: SIGNED

Today, drought and salinity constitute two of the most severe threats to global food security, and are rapidly increasing as climate changes further progress. These stresses have a large impact on plant’s ability to use nutrients, resulting in a significant reduction in crop yields. Accordingly, ca. €90 B/year of economic losses occur due to salinity and drought, representing 800+ M ha of arable land affected globally. To tackle this clear socio-economic problem, players in the BioAgriculture sector have been developing a new type of solutions called biostimulants, i.e., compounds/components or microorganisms stimulating plant responses improving plant’s utilization of nutrients and tolerance to abiotic stresses. Despite these solutions already existing on the market, mostly based on seaweed extracts, they typically rely on the application of large doses, rendering the solutions expensive and difficult for the farmers to implement in existing agronomic practices. To address this market gap, Agrobiomics is developing a new biostimulant solution produced by bacterial fermentation, which effectively tackles the limitations of existing solutions. Agrobiomics’ patent protected solution delivers unprecedented levels of potency towards improving crops yield under drought and salinity stress at a very low dosage. Having already the solution validated for different types of crops (i.e., broadacre and Fruits & Vegetables), Agrobiomics now aims to scale-up the production and demonstrate the efficacy of the solution in large field trials, which are deemed essential to develop the regulatory package needed for approval of the product. These activities will be the tipping point to unlock the commercialization of the biostimulant product. Therefore, the EIC-A support is critical to co-finance the final technology maturation steps and market entry, thus allowing Agrobiomics to disrupt the biostimulant market with a biostimulant that makes agriculture resilient to climate change.

Keywords: biostimulants agriculture resilience abiotic stresses biotechnology bioprocesses sustainable farming biomanufacturing fermentation
InterPoc, by Ampa Medical. A discreet, easy-to-use, internal solution for fecal waste management in ileostomies. (InterPoc by Ampa)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2400000.0
EU funding (EUR): 2400000.0
Participants: 1
Project status: SIGNED

Over 1 million people worldwide live with an ileostomy, a diversion of the intestine through an opening in the abdominal wall after removal of part of the intestine. This is usually the result of cancer or bowel disease and has thus far necessitated that the patient wears a bag on their abdomen to collect feces in at all hours, for the rest of their lives. Ileostomates face severe skin problems due to leakage of liquid and highly acidic, enzyme-rich feces onto the skin. They are socially stigmatized due to uncontrollable odors and sounds from their stoma. Their sleep, ability to exercise, sexual wellbeing and mental health are all disturbed. These issues severely affect the quality of life of ileostomates and cost the EU, UK, and US collectively more than €1 billion per year. Ampa Medical will radically improve the lives of ileostomates, providing a discreet, easy-to-use, internal solution for fecal waste management. InterPoc is a tampon-like device that sits inside the intestine, inserted through the stomal opening with a combined insertion/withdrawal sleeve, all covered by a protection shield. This solution would disrupt a market otherwise dominated by a few large companies who all produce ostomy bags and have been doing so for 75 years. Ampa maintains a strong network of patients and medical professionals in ostomy care, and product development is guided by professors in gastroenterology, stoma care nurses, and feedback from ileostomy patient groups. InterPoc is proven safe in clinical safety studies in humans completed at Rigshospitalet, the largest hospital in Denmark. Each InterPoc contains a fraction of the amount of plastic as a traditional ostomy bag and represents a leap of need-based, female-led innovation in an otherwise tradition-anchored field. We hope to receive funding to bring us to TRL8 by establishing a production setup, obtaining IP protection and regulatory approval (MDR and FDA), as well as planning and executing additional clinical trials.

Keywords: stoma care,freedom beyond the bag,internal absorbing device for liquid intestinal waste
Dynamical tests of dark matter in Local Group galaxies: shortcomings and new avenues (DiaLoGues)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: ERA Fellowships (HORIZON-WIDERA-2023-TALENTS-02, 2023)
Start date: 2025-05-02
End date: 2027-05-01
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: SIGNED

The distribution of dark matter in the Milky Way and neighbouring Local Group galaxies is an important indicator of the nature of dark matter. Accurately determining the smooth distribution of dark matter in these galaxies and the degree of clumpiness (abundance of luminous and dark satellites) encodes information about the properties of dark matter and the interplay between the baryonic and dark sectors in the formation and evolution of galaxies. As well as being auxiliary quantities in interpreting the results of multichannel dark matter searches. Thanks to significant investments in observational resources by international and, in particular, European countries, we now have access to an enormous amount of detailed, high-quality astronomical data that allow us to view Local Group galaxies as complex systems in interaction with their environment. The DiaLoGues project will help harvest these exquisite data's full potential in interdisciplinary dark matter searches with a hybrid approach. On the one hand, we will address biases in the smooth, galactic-scale distribution of dark matter in current chemo-dynamical models of the Milky Way and neighbouring dwarf galaxies. On the other hand, we will search for peculiar features in the spatial distribution and kinematics of individual stars in Local Group dwarf galaxies, which will then be confronted with signatures of luminous and dark mergers in state-of-the-art hydrodynamical simulations. In this way, the theoretical link between observations and the accretion history of the host dwarf galaxy will be provided. DiaLoGues will be a transfer-of-knowledge agent between the astroparticle and astrophysics communities, contributing to the interdisciplinary endeavour to constrain the underlying particle physics model that governs dark matter at the microscopic scales.

Keywords: milky way,dwarf galaxies,dark matter searches,galaxy dynamics,gaia,stellar spectroscopy,cosmological simulations
Breakthrough Vertical INTermediate thermochemical convERsion technology to produce carbon-negative biogenic fuels for maritime shipping (VINTER)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 1680000.0
EU funding (EUR): 1680000.0
Participants: 1
Project status: SIGNED

Maritime shipping is responsible for 3% of global CO2 emissions and today, more than 99% of shipping vessels still run on conventional fossil fuels, such as heavy fuel oil (HFO). Conversely, this means there is significant potential for biofuels to replace maritime fuel consumption and support the European Union’s (EU) initiatives, such as FuelEU Maritime, and the International Maritime Organization's targets to reduce greenhouse gas emissions: 40% carbon intensity reduction by 2030 and 70% by 2040, increasing the adoption of zero or near-zero emission fuels and energy sources to at least 5%, with an aim to reach 10%, of total energy consumption by 2030. To achieve this goal in an economically and environmentally sustainable manner, it is paramount to (i) valorise untapped waste (feedstock) sources and (ii) to achieve “drop-in” biofuel quality, which means the possibility to replace conventional fossil fuels without any modifications to the existing fuel infrastructure, such as engines, fuel tanks, pumps and valves, and supply systems. However, despite advancements in biofuel technologies, current solutions face hard challenges related to fuel quality, usability in existing infrastructure, and scale-up of production capacity. SAGAVA is here to change this. With a patented breakthrough innovation in thermochemical biomass conversion, called "VINTER" (Vertical Intermediate Conversion Technology), consisting of a first-of-a-kind combination of intermediate pyrolysis with an integrated post-reforming step using no external catalysts, in one single highly modular reactor, SAGAVA uses waste biomass to generate three value-added products: VINTER biofuel, carbon-negative biochar, and hydrogen-rich syngas, directly contributing to the decarbonisation of maritime shipping and the transportation sector. This project will be key to qualify VINTER for commercial implementation using a pilot unit with a biomass provider, and prepare to deploy and scale-up on 3 continents.

Keywords: advanced biofuels biomass thermochemical conversion catalytic pyrolysis biochar syngas carbon credits decarbonisation maritime fuels
Early diagnosis of gynaecological cancers with an innovative AI approach (OvAi Platform)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 36.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Ovarian cancer (OC) poses a major health challenge due to its late diagnosis and significant impact, being the fifth leading cause of cancer-related deaths worldwide. It often affects women in their productive years, causing economic strain through healthcare costs and lost productivity. Current diagnostic methods, such as transvaginal ultrasound, are limited in accuracy and depend on operator skill, making it hard to distinguish between malignant and benign lesions. This underscores the urgent need for more precise diagnostic tools. SynDiag's OvAi Platform addresses these challenges by revolutionizing Digital Gynecological Oncology. OvAi integrates with ultrasound machines to provide real-time processing and virtual biopsy for accurate cancer detection. It enhances ultrasound scans with standardized readings and high accuracy in predicting tumor types, even in early stages. OvAi consists of OvAi Focus for objective ultrasound analysis and OvAi X for virtual biopsy, improving diagnostic outcomes. Clinical validation shows OvAi's effectiveness, surpassing existing devices in accuracy. OvAi’s AI-powered algorithms analyze ultrasound scans, providing detailed insights into tumor morphology and histology, aiding in precise treatment planning. It supports telemedicine and integrates with existing healthcare systems, optimizing cancer diagnosis and management. SynDiag's innovation in early OC diagnosis revolves around leveraging AI as a crucial tool for gynaecologists. OvAi, our groundbreaking AI-based technology, addresses the subjective nature of sonography by providing objective evaluation and diagnostic support. It empowers gynaecologists with expert knowledge and automatic diagnostic suggestions, enabling precise examinations and reducing the likelihood of misdiagnosis.

Keywords: ovarian cancer early diagnosis,artificial intelligence telemedicine virtual biopsy gynecology ultrasound analysis
Revolutionizing Mixed Reality: Optical component that keeps digital images always in focus (Lark-Lightguide)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The broad adoption of Mixed reality (MR) in the industrial sector will pave the way for a transition to Industry 5.0, a human-centric, digitalized industry. MR promises a huge impact in healthcare, education, manufacturing, automotive, logistics, construction, cybersecurity, among others. However, two crucial technical limitations are hindering the widespread adoption of MR across industry namely vergence-accommodation conflict and comfort. Vergence-Accommodation Conflict (VAC), results from the mismatch in the brain's cues regarding the distance between virtual 3D objects and the focusing distance required for the eyes to focus on that object. This causes nausea, dizziness, headaches, eyestrain, which categorically impedes the use of the technology for more than 40 consecutive minutes. Comfort issues caused by a lack of technical setup and design which accounts for individual vision needs, forcing prescription glass wearers to have to wear their glasses underneath the VR headset, resulting in co discomfort and impairing the quality of their work. We, at Lark Optics, have developed Lark-Lightguide, an optical component that features a nanophotonic chip, which safely bypasses the eye's natural optics. Lark-Lightguide keeps digital images always in focus, resolving the conflicting visual cues of traditional AR/VR systems (VAC) and circumventing need for prescription glasses, meaning that glasses wearers can see clearly without prescription lenses below the VR headsets. Lark Optics is a pioneer in nanophotonic technology aimed at creating next-generation optical components for VR and AR display applications. Led by Pawan, CEO and former Royal Academy of Engineering Enterprise Fellow, the team has a proven track-record of successfully delivering engineering projects to create prototype VR and AR headsets. We have entered into 4 joint development (JD) projects, with global leaders in electronics and automotive production.

Keywords: augmented reality,virtual reality,optical component,lightguide,nanophotonic chip,always in focus technology
Laser Engineered Surfaces/Interfaces for Advanced Batteries (LESIA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark,United Kingdom,Germany,Spain,Czechia,Italy,China,United States,Hong Kong
Call: MSCA Staff Exchanges 2022 (HORIZON-MSCA-2022-SE-01, 2022)
Start date: 2024-03-01
End date: 2028-02-29
Duration (months): 48.0
Total project cost (EUR): 1311657.14
EU funding (EUR): 1288000.0
Participants: 11
Project status: SIGNED

Addressing climate change is humanity’s greatest challenge in the 21st century. The European Green Deal has declared that Europe is committed to realizing a climate-neural society by 2050. To reduce carbon dioxide emissions from transport, power, and industry sectors, Europe must urgently change the energy paradigm, shifting to renewables. However, renewables are all intermittent, and facing the storage challenge. Secondary batteries offer highly efficient electrical energy storage capability, and become the key technology to achieve the large-scale application of solar/wind green energy and thus support the deep decarbonization of European energy system. European Commission estimated that the value of battery industry can reach €250 billion by 2025. Existing battery systems still suffer from low energy density and safety issues. There is huge gap between commercial batteries and advanced battery proposed by BATTERY2030+. Employing novel electrode materials are considered as promising strategies to develop next generation high performance batteries. However, these high capacity electrode materials raise significant challenges (dendrite, volume change, and degradation etc.) in practical application, which limit their commercialization prospects. LESIA will develop and construct bio-inspired surfaces/interfaces with electrochemical functionalities for the components of batteries using laser-based fabrication and emerging nanoscale characterisation techniques. LESIA will develop new surficial chemistry, and regulate the decisive electrochemical interfacial processes, and thus address the challenges of the high performance anodes and cathodes for next generation advanced batteries. LESIA will create new paradigm of advanced battery development by using cutting-edge laser-based surface/interface engineering technologies.

Keywords: surfaces and interfaces,laser fabrication,micro nano metrology and characterisation,advanced batteries
Design of Bioinspired Chromophore-Protein Complexes for Color Converting Layers of Organic Light Emitting Diodes (deBioLED)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-01
End date: 2025-09-30
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: SIGNED

In deBioLED, I seek to design bioinspired chromophore-protein complexes of high red emission efficiency to fabricate the next generation of eco-friendly color converting layers (CCLs) of organic light-emitting diodes (OLEDs). Despite OLEDs already consume 70% less energy than typical lighting sources, their production still depends on a high input of energy and use toxic components yet yielding devices of poor stability. Given the on-going energetic and environmental crisis, it is crucial to push the development of OLEDs towards the usage of greener and recyclable materials, together with faster and simpler fabrication protocols. I propose to construct supramolecular assemblies of great color purity and photostability by inserting synthetic chromophores into protein matrices to compose CCLs that will be coupled with OLEDs to render white light emitting devices. These renewable CCLs will allow the production of efficient OLEDs with only a few layers to avoid creation of morphological defects, which helps to prolong the devices durability. The CCLs will be built with de novo designed proteins, scaffolds that offer a precise way to accommodate synthetic chromophores by controlling their relative distance and environments. With that protein platform, I will tune the chromophores emission properties and promote energy transfer paths similarly to natural photosynthetic pigment-protein complexes. I will use two different red emitting chromophores to convert part of the OLED blue emission to red, so the combination of emitted colors will yield white light. Red light extraction from CCLs will be boosted by enhancing the density of chromophores on the excited state as one of them will transfer the acquired excitation energy from the OLED to the other in a cascade of events, studied by ultrafast time-resolved spectroscopy. Thus, by engineering intricated photophysical phenomena within de novo proteins I will deliver a new strategy to improve the efficiency of bioinspired CCLs.

Keywords: organic light emitting diodes,color converting layers,de novo protein design,solution processed devices,biogenic matrices,resonant energy transfer,ultrafast spectroscopy