Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Innovative 5R SOLutionS for Textile Integrated Circular Economy (SOLSTICE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Innovation actions
Countries involved: France,Italy,Germany,Spain,Belgium,Netherlands,Türkiye
Call: Circular Cities and Regions Initiative (CCRI)’s circular systemic solutions (HORIZON-CL6-2023-CIRCBIO-02, 2023)
Start date: 2024-05-01
End date: 2027-10-31
Duration (months): 42.0
Total project cost (EUR): 11098450.0
EU funding (EUR): 10165375.39
Participants: 25
Project status: SIGNED

SOLSTICE aims at demonstrating 4 replicable systemic solutions for the territorial deployment of the circular economy (CEC) for the major industrial sector of textiles (62Mt produced/year). All steps of waste prevention and management will be included in a 5R strategy: Refuse/Reduce, Reuse, Repair, Repurpose, Recycle. The solutions developed can be replicated and cross-linked with the plastics value chain. SOLSTICE will: • Develop tools and strategies to implement the 5R approach: oFor the 4R Refuse/Reduce, Reuse, Repair, Repurpose: - Engage the different stakeholders (industrial companies, local authorities, citizens) to revise their supply chains / behaviour, and become more sober, circular and sustainable. - Scope and map current state, carry research on and analysis of relevant circular interventions per territory, - Create a methodology and blueprints of CEC interventions to be tested/piloted - Define circular guidelines and indicators oRecycle: Demonstrate innovative chemical recycling technologies, able to treat efficiently part of the major streams of polymers in textiles and plastics (PET, elastane, polyamide, polyurethane) in mild conditions. The technologies allow to recycle multicomponent and bio-based materials, complex streams, and to recycle textile into textile or coating into coating (closed-loop) or into added-value applications (open loop). They are easily adaptable and allow a local recycling. • Set-up a traceability system based on a Digital Product Passport and designed in relation to existing initiatives. The demonstration will take place in 4 EU representative and complementary territories. Knowledge-transfer and cooperation between the cities and regions involved, and with CCRI and other stakeholders and projects, will ensure an optimised development and deployment of the new circular concepts, as well as the replicability of the concept and a maximal impact. The deployment of SOLSTICE could save 4.3-10.8 Mt GHG emissions/year by 2030.

Keywords: textiles,polymers,refuse,repair,reuse,repurpose,recycle,collection,sorting,awareness,sobriety,behavioural change,polyester,pet,polyamide,polyurethane,elastane,chemical recycling
Unraveling the role of O-glycosylation in pancreatic ductal adenocarcinoma. (GlycoPDAC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-08-01
End date: 2027-07-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancer type, with a 5-year survival rate of just 10%. This is primarily due to late-stage diagnosis and resistance to current treatments. Therefore, understanding the molecular mechanisms driving PDAC progression is critical for developing more effective diagnostic and therapeutic approaches. Glycosylation, one of the most prevalent post-translational modification, is fundamentally altered in PDAC. The two clinically significant subtypes present in PDAC, called Classical and Basal, have distinct glycosylation profiles that affect tumor cell biology and its interactions with the microenvironment and immune system. Despite its importance, the particular mechanisms involved are poorly understood. This project aims to elucidate how glycosylation drives PDAC, by characterizing the glycoproteins involved in different subtypes. We are particularly focus in the glycosylation enzymes GalNAc-T1 and GalNAc-T3, which have fundamental yet distinct roles in Classical and Basal cancer cells. However, their substrate proteins and underlying mechanisms remain largely unknown. Using bump-and-hole engineering, combined with click chemistry and mass spectrometry, we will pinpoint the glycoprotein substrates and glycosylation sites modified by these isoenzymes, offering unparalleled insight into the roles of glycans in PDAC. We will also characterize the biological functions of these glycoproteins through biochemical, cell biology, and immunological methods. By revealing how these glycoproteins influence cancer cell biology and immune recognition, this project could uncover novel mechanisms involved in PDAC progression, which can lead to the identification of new biomarkers or therapeutic targets, potentially improving patient outcomes.
South Slavic CLItics in language Contact contexts (CLIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-03
End date: 2027-02-02
Duration (months): 24.0
Total project cost (EUR): 183600.96
EU funding (EUR): 183600.96
Participants: 1
Project status: SIGNED

The project investigates the effect of language contact on the structural make up of clitics through the analysis of their use and function in three South Slavic contact varieties: Molise Croatian (MC), Burgenland Croatian (BC) and Torlak (TK). Although clitics have been extensively examined in standard(-ized) Slavic languages, very little attention has been paid to marginalized and/or endangered varieties. Besides the language preservation and documentation effect, the study aims to provide an insight in the layering of complexity in the syntactic structure of clitics by examining their inventories, the structural layers truncated in the simplification triggered by contact as well as those interacting with the structures of the other contact variety, specifics of the clitic cluster and the presence or absence of clitic doubling and clitic climbing. The chosen varieties constitute a minimal triple, since 1) MC has had a very extended contact with Italian and Italo-Romance varieties, having a fairly rich clitic system, 2) BC has been in contact with Austrian German, displaying very scarce cliticization phenomena and 3) TK has been in contact with Serbian Standard, Macedonian and Bulgarian, all with very rich clitic systems. Empirically, the project combines fieldwork in terms of a sociolinguistic questionnaire and elicitation tasks in the three areas with a corpus-based study. The latter extends an ongoing study on Torlak to further marginalized South Slavic varieties in order to provide a wider perspective onto contact-related issues. The data is treated both quantitatively and qualitatively. The results of this investigation will therefore not only fill the gap in the empirical description of the use of clitics in understudied varieties and types of contact, but they will also provide a contribution to the fundamental questions on the nature of human language.

Keywords: clitics,molise croatian,burgenland croatian,torlak,south slavic,language contact
Biocarbon based Polymers for Sustainable Material Development (D-Carbonize)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,Belgium,Netherlands,France,Germany
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2023-03-01
End date: 2027-11-30
Duration (months): 57.0
Total project cost (EUR): 3213326.06
EU funding (EUR): 3168331.2
Participants: 18
Project status: SIGNED

D-Carbonize´s approach targets biocarbon recycling into valuable starting materials for the chemical/polymer industries and will primarily provide innovative low-carb catalysis solutions. The use of biocarbon is advantageous in many respects as it is renewable, generally abundant and non-toxic, and it represents easy-to-handle carbon reagents even on larger scale. Despite the lack of universal (catalytic) strategies available for biocarbon valorization into monomers and polymers, recent advances in catalysis science have demonstrated the engineering and use of new promising metal- and organo-catalysts with high potential to overcome these limitations, thereby creating the necessary feasibility to transform biocarbon into (1) fine chemicals such as carbonates, carbamates, carboxylic acids, and esters, (2) pharmaceutical synthons, and (3) biomass/CO2-based polymers. Thus, catalysis has already been shown to be a useful technology for biocarbon valorization but has been rarely used in the wider context of new and functional biocarbon based monomer/polymer development. The use of the latter helps to shape the future of functionalized poly-esters/carbonates/amides and their subsequent utilization in novel tailor-made and commercially relevant materials. Furthermore, this project will also explore depolymerization pathways to recycle the synthesized polymers obtaining new monomers and/or other added-value molecules that could re-enter the loop and be used in new polymers and materials. The network will recruit 12 doctoral candidates, who will be awarded double doctoral degrees by two universities in two different countries at the end of the training program. D-Carbonize brings together leading high-education institutions, research centers and companies to form an innovation community able to offer excellent research and training both in R&D and entrepreneurship.

Keywords: homogeneous catalysis,heterogeneous catalysis,organocatalysis,co2 based monomers,bio based monomers,polymers,coatings,adhesives,packaging materials,sustainability
sociogeNEsis of criMinal nEtworks: reconStruction, dIscovery and diSruption (NEMESIS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1498794.0
EU funding (EUR): 1498794.0
Participants: 1
Project status: SIGNED

Europol defines criminal networks as a modern version of the Hydra mythological creature, with obscure genesis, fluid structure and multifaceted evolutions. Leveraging a unique synergy between Social Sciences and Statistics, NEMESIS departs from current practice to translate the main obstacles (i.e., data incompleteness and complexity) underlying the reconstruction, discovery and disruption of these modern criminal networks into a unique resource for crucially expanding available knowledge and policies. This ambitious perspective builds on three somewhat overlooked, yet fundamental, observations. First, data missingness in criminal networks can be, in fact, a fundamental source of information on the structure and secrecy strategies of organized crime, and, as such, should be embraced and not disregarded for network reconstruction. Second, the complexity and multiplexity of covert and overt interactions among criminals may hide a wealth of yet unexplored knowledge on the formation, mutation and sociogenesis of criminal networks, hence invaluable for their discovery. Third, “cutting” Hydra heads without realistic predictions of the corresponding re-generation processes undermines not only the development of innovative law-enforcement disruption strategies, but also the identification of more nuanced high-value targets. NEMESIS transforms these perspectives into rigorous, interpretable and practically-impactful generative statistical models of criminal networks and introduces innovative concepts of secret criminal species, covert networking activity codes and dark evolutionary trees. This perspective is expected to revolutionize current practice of conceptualizing, reconstructing, analyzing and disrupting criminal networks, while opening new avenues for the creation of frontier data-related resources, social theories, law-enforcement strategies and public policies.

Keywords: social network analysis,computational social sciences,quantitative criminology
Adaptive virtualization for AI-enabled Cloud-edge Continuum (CloudSkin)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: World-leading Data and Computing Technologies
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Switzerland,United Kingdom,Ireland
Call: Cognitive Cloud: AI-enabled computing continuum from Cloud to Edge (RIA) (HORIZON-CL4-2022-DATA-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 3405322.51
EU funding (EUR): 3405322.5
Participants: 12
Project status: SIGNED

As of today, 80% of the data processing and analysis occurs in cloud data centers, and only 20% of processing occurs at the edge. This incipient exploitation of edge resources increases time to value and prevents business processes, decisions, and intelligence to be taken outside of the data center, which prevents Europe to unlock an entire set of new opportunities to serve different industries and use cases in Europe in the next years. To help to materialize the European bid on a true continuum in the next few years, CloudSkin pursues to build a cognitive cloud continuum platform with three main innovations: 1. The CloudSkin platform will leverage AI/ML to optimize workloads, resources, energy, and network traffic for a rapid adaptation to changes in application behavior and data variability, re-configuraing the "sweet spot" between the cloud and the edge in the face of the rapid varying conditions; 2. The CloudSkin platform will also help users to achieve “stack identicality” across the Cloud-edge continuum, whereby the same (legacy) software stacks (e.g., MPI programs) running in data centers can seamlessly run at remote edges. The development of a new lightweight, portable virtualizaion abstraction will be paired with the development of new confidential abstractions to protect data while it is in use; and 3. CloudSkin will also contribute to prepare the needed infrastructure to integrate the new virtualized execution abstractions into the virtual resource continuum, particularly, for those Cloud-edge applications composed of small tasks with fast data access and sharing requirements. The infrastructure will expose the relevant control knobs to enable dynamic reconfiguration of resources as assisted by the AI/ML-based orchestration plane in the CloudSkin platform. Altogether, the above innovations are the strategic elements of what we envision as the new “cognitive continuum for the cloud and edge".

Keywords: cloud edge computing ai ml optimization virtualization confidential computing storage
Establishment of a FramewORk for Transforming current EPES into a more resilient, reliable and secure system all over its value chain (eFORT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Spain,Netherlands,Italy,Germany,Ukraine,Belgium,Cyprus,Greece,Norway
Call: Reliability and resilience of the grid: Measures for vulnerabilities, failures, risks and privacy (HORIZON-CL5-2021-D3-02, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 9321022.5
EU funding (EUR): 7996531.0
Participants: 23
Project status: SIGNED

Prompted by the need to comply with environmental and societal concerns, Electrical Power and Energy Systems are undergoing an unprecedented transformation, demanding urgent upgrades to make them more reliable, resilient and secure. Modernization of current grids will greatly reduce the frequency and duration of power blackouts, diminish the impact of disruptive events and restore service faster when outages occur, creating broad benefits to society and economy. eFORT approach will enable the further upgrading of the energy grid without affecting the security of supply and increasing their reliability and resiliency against extreme weather events, man-made hazards and equipment failures. eFORT addresses this complex challenge by gathering a consortium of 24 partners, from 10 EU countries, that provides the needed expertise. The project will put in place a set of solutions at the cyber and physical layers for detecting, preventing and mitigating vulnerabilities and threats. Among them, an interoperable Intelligent Platform will set a common foundation for grid characterization and vulnerability overseeing, as well as gather information from smart grid components and apply heavy-duty algorithms, whereas Asset Management developments will strengthen grid infrastructure robustness, which will be empowered by the addressed Digital Technologies. All these elements will be validated in relevant environments coming from 4 demo cases covering the whole grid value chain: (i) a transmission network (The Netherlands); (ii) a remote distribution grid (Italy); (iii) a digital substation in Ukraine; and (iv) a micro-grid in Spain. Moreover, eFORT relies on several horizontal actions aiming at empowering EPES players by establishing a common regulatory and standardisation framework, performing technical and cost-benefit analysis, and evaluating new related business models and replication potential, in the pathway towards a more sustainable energy system.

Keywords: grid reliability and resilience,cybersecurity,substation,digital technologies,dso,tso,risks,failures,microgrids,epes,assets and infrastructures management,secure and privacy data management
Deep Brain Neuromodulation using Temporal Interference Magnetic Stimulation (TIMS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2022-11-01
End date: 2024-04-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Five out of ten diseases leading to long term-disability are related to the brain, including stroke, depression or dementia. Despite tremendous progress in neurotechnology, there is still no effective treatment option available for many brain-related disorders. A very promising approach to treat brain disorders uses transcranial electric or magnetic stimulation (TES/TMS) to directly influence brain activity related to specific symptoms. However, these methods are limited in their spatial resolution, specificity and ability to reach deep brain areas. The aim of the proposed project is to develop a technical and experimental proof-of-concept for a new non-invasive tool that allows for millimeter- and millisecond-precise modulation of neural activity in superficial and deep areas of the human brain. Capitalizing on temporal interference effects, the device will apply high carrier frequency magnetic fields through a pair of coils. By modulating their relative phase, the combined fields will induce a locally amplitude-modulated electric field in the brain. As neural tissue is insensitive to unmodulated high-frequency fields (>1kHz), but responds to low-frequency amplitude-modulated fields, only brain regions will be stimulated where the combined field is amplitude-modulated. Building on the resulting versatility of stimulation frequencies and waveforms, we aim at providing proof for cell-type specificity of such temporal interference magnetic stimulation (TIMS). Moreover, we aim at providing proof for the feasibility of targeting neural activity at millisecond-to-millisecond precision. Availability of such device offering high spatial resolution, depth selectivity, steerability, as well as closed-loop-compatibility and cell-type specificity would mark a major break-through for clinical neuroscience. Together with two partners from industry and a partner for technology transfer, we strive for fast translation of expected research results into innovative products.
Nonlinear topological Floquet phases in a fiber ring experiment (T-REX)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 2
Project status: CLOSED

The realm of topological photonics relies on extreme flexibility of optical media for sculpting Hamiltonians with arbitrary properties in real and synthetic dimensions. Topological effects in the optical domain can provide robust waveguiding and stable lasing, which is of extreme interest for integrated photonics. A powerful tool to imprint topological properties is periodic Floquet driving, which maps the energy bands onto a periodic quasienergy spectrum. Even richer physics was predicted to emerge if interactions are added into the system. However, the experimental studies of interacting Floquet matter remained scarce due to absence of suitable platforms. This project relies on a system of coupled fiber rings to realize a synthetic lattice for the study of interacting topological Floquet phases. This platform provides a unique combination of intrinsic Floquet nature due to periodicity of the light propagation in rings, full control over complex couplings, and tunable Kerr nonlinearities in the fibers, thus allowing to engineer many-body Floquet Hamiltonians and study topological physics inaccessible with other systems. Based on these unique features, the action aims at demonstration of novel topological Floquet phases and topological pumping in presence of interactions. This project stays at the cornerstone between topological physics, photonics, and nonlinear fiber optics, and perfectly fits the applicant’s experience for preparing him for a future career as an independent researcher.

Keywords: topological photonics,floquet driving,topological pumping,many body hamiltonians,nonlinear fiber optics