Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Fanconi anemia : a disease model to understand causes and consequences of common fragile site instability. (FAtoUnFRAGILITY)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: France
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-06-01
End date: 2020-05-31
Duration (months): 60.0
Total project cost (EUR): 1462383.0
EU funding (EUR): 1462383.0
Participants: 1
Project status: CLOSED

Originally described by cytogeneticists, common fragile sites (CFSs) are chromosomal regions known for their susceptibility to break and rearrange aberrantly, thus altering the expression of genes located therein. CFS instability is associated with tumor development and pathogenic copy number variations. Recent advances have significantly contributed to dissect the molecular bases of CFS instability, yet a unifying model for their unique breakage propensity has not been determined. Fanconi anemia (FA) is a chromosomal instability syndrome featuring congenital abnormalities, bone marrow failure and cancer predisposition, characterized by an increased CFS fragility. FA is thus an ideal model to understand the mechanisms underpinning CFS instability and the mechanistic link between CFS instability and the pathogenesis of disease phenotypes. I propose to use FA cellular models to examine the molecular events leading to CFS instability, and FA mouse models to investigate the consequences of deletions, amplifications or rearrangements involving CFSs on the expression of genes regulating critical signal transduction pathways involved in cell survival, proliferation, and differentiation. Exploring these mechanisms can lead to the development of chemopreventive or therapeutic strategies targeting aberrant gene expression or pathological pathways.
Collaborative RObotic Solution for Advanced Inspection of Complex Composite parts (CRO-INSPECT)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Spain,Spain
Call: Complex (composite) part Ultrasonic inspection facilitated by man-robot collaboration (H2020-CS2-CFP02-2015-01, 2015)
Start date: 2016-09-01
End date: 2019-08-31
Duration (months): 36.0
Total project cost (EUR): 352056.25
EU funding (EUR): 349993.75
Participants: 3
Project status: CLOSED

Highly integrated composite parts have begun to enter the market. Their inherent complex structure makes more difficult inspection activities being crucial the development of more flexible, more reliable and faster NDT solutions. Regarding NDT methods, Ultrasonic testing (UT) techniques are suitable for the inspection of large and hidden areas and recently developed ones, like guided waves, have shown potential for remote inspection. Currently, most of inspections are performed manually, which entail two key disadvantages: an excessive amount of time and the possibility of potential safety failures due to human errors. To solve these issues, automation of inspection process has been envisioned as strategic solution. The integration of robotics in manufacturing lines has proved improvements in process reliability, reduction of manufacturing times and, therefore, costs. However, many industrial operations cannot be fully automated at a reasonable cost. In such a case, human-robot cooperation may be the most cost-efficient and productive solution. This is precisely the scope of CRO-INSPECT. The project aims at creating a new concept of hybrid work cell for inspection, where humans and robots perform collaboratively inspection activities using advanced UT techniques. It aims at developing a sound inspection solution with enhanced robotic capabilities, enabling faster and more reliable inspections, and helping operator during the inspection of complex composite parts, reducing this way recurring manufacturing costs. The specific goals of the project will be to generate an advanced and safe human/robot collaboration work cell prototype for robotic assistance of the operator during inspection; and to generate a new inspection system based on advanced UT, capable of reaching low access areas of parts. By achieving these objectives, the consortium expects to provide a step forward in the current industrial solutions for automated NDI of large aircraft components.

Keywords: ultrasonic inspection,human,robot collaboration,automation,ultrasonic guided waves
REsilient INteractive applications through hyper Diversity in Energy Efficient RadioWeaves technology (REINDEER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Partnership: 5G PPP (cPPP)
Countries involved: Austria,Spain,Austria,Belgium,Sweden,Sweden,Sweden,Belgium
Call: 5G PPP – Smart Connectivity beyond 5G (H2020-ICT-2020-2, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 4644460.0
EU funding (EUR): 4644460.0
Participants: 11
Project status: SIGNED

The REINDEER project will develop a new smart connect-compute platform with a capacity that is scalable to quasi-infinite, and that offers perceived zero latency and interaction with an extremely high number of embedded devices. It will thereto develop “RadioWeaves” technology, a new wireless access infrastructure consisting of a fabric of distributed radio, computing, and storage resources. RadioWeaves can be deployed as panels mounted on walls and ceilings. It brings a large number of antennas and intelligence close to devices offering consistently excellent service at minimal transmit power and making very efficient usage of network bandwidth and energy. Technologically, RadioWeaves advance the ideas of large-scale intelligent surfaces and cell-free wireless access, two theoretical concepts that bear great promise to offer capabilities far beyond 5G networks. We will characterize channels based on measurements and develop distributed platform architectures to realize the great potential in actual deployments. We will develop protocols and algorithms to establish novel resilient interactive applications that require ‘real-time’ and ‘real-space’ cooperation, for future robotized industrial environments, immersive entertainment, and intuitive care, We will co-design focusing algorithms and protocols for enhanced interaction with many energy-neutral devices. REINDEER will provide experimental proof-of-concept in versatile testbeds. Industrial partners fostering innovation team up with academic experts in the REINDEER consortium. The project will reinforce the technological leadership in Europe and create new business opportunities in beyond 5G infrastructure and network operation both licensed and unlicensed bands, the focused vertical domains, and in private networks. We will execute an ambitious communication plan towards industry, pre-standardisation, and a broad public, disseminate through high-impact publications, and organize topical trainings.

Keywords: radioweaves,distributed architectures and computing,positioning,cell free networking,ultra reliable,communication,low energy nodes,proof of concept
Nonlinear astrophysical dynamos: a novel data-driven approach for interscale dynamics (DynMode)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

Magnetic fields are ubiquitous in the Universe, and are thought to play a key role in evolution of stars, planets, accretion discs and black holes. Although it is generally accepted that these fields are created by the motions of conductive fluids – hydromagnetic dynamos, there is no ab initio predictive theory for their origin and evolution. Because of nonlinear coupling between magnetic field and fluid flow, and also due to extreme parameters of astrophysical objects, dynamos arise from interactions of the flow and field on extremely vast range of space and time scales. This limits the utility of computational approaches. The DynMode project seeks to elucidate the nature of interscale nonlinear interactions using the novel data-based approach from dynamical systems theory, and to create nonlinear reduced-order models of astrophysical dynamos that represent dynamics on large, intermediate and small scales. This is crucial for our understanding of the operation of astrophysical dynamos. During this Fellowship, we will decompose the data of dynamo flows into dynamically relevant blocks (modes), identify principal nonlinear dynamics and energy exchange among those blocks, and create a reduced-order dynamo model by projecting the flow onto them. By analyzing data sets from self-sustained and convective-driven dynamos in different geometries, we will also address the question of intrinsic dynamo features as compared to influence of secondary physical effects and flow geometry. This approach, applied for the first time in dynamo research, will explain interactions between small-scale and large-scale dynamos and their nonlinear saturation, as well as physics of weak and strong geodynamos. The project, bringing together physical modelling of the dynamos, study of the flow and magnetic field structures, and innovative data-driven strategy, has a potential to significantly advance the current understanding of dynamos, and impact wider research community in fluid dynamics

Keywords: astrophysical dynamos,geodynamo,solar dynamos,dynamo saturation,reduced order modeling,nonlinear interactions,magnetic fields,modal decomposition
Accessible, reliable and affordable solar irrigation for Europe and beyond (SolAqua)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Coordination and support actions
Countries involved: Spain,Italy,Spain,Spain,Italy,Romania,France,Portugal,Morocco,Portugal
Call: Market Uptake support (H2020-LC-SC3-2020-RES-IA-CSA, 2020)
Start date: 2020-10-01
End date: 2023-09-30
Duration (months): 36.0
Total project cost (EUR): 1757215.0
EU funding (EUR): 1757211.0
Participants: 12
Project status: SIGNED

SolAqua will increase the share of renewable energy in Europe by facilitating market uptake of solar irrigation (SI). By combining photovoltaic and hydraulic technology with high efficiency irrigation, SI can provide energy for irrigation with 0 emissions and at a cost of up to 70% lower than existing fossil-fuel based solutions. The potential of SI to change the energy model of European farming is huge as irrigation demands large amounts of energy for pumping water to crops. Alongside a €4 bn energy bill, the current fossil-fuel based energy model of irrigation also has a high environmental cost; it produces 16 million tons of CO2 every year, approximately 15% of the EU’s total CO2 emissions from agriculture. Nevertheless, despite its potential benefits, market uptake of SI is being prevented by a number of non-technological barriers. Also, there is a lack of awareness and skills regarding SI among irrigators and other stakeholders, such as local SMEs and public authorities. SolAqua is the answer from a coalition of relevant stakeholders to overcome this situation. In a first stage, SolAqua will produce 7 key enabling materials and tools needed for SI market uptake but which are currently missing, such as quality standards and economic and environmental assessment methodologies. In a second stage, SolAqua will carry out a far-reaching dissemination and communication plan in order to attract more than 300,000 stakeholders in Europe and North Africa to SI in general and, in particular, to SolAqua’s exploitation plan. This exploitation plan will allow for the triggering a well-functioning SI market by producing a joint SI promotion of at least 100 MW (more than €120 M in investments) which will act as a flagship for the solution. Also, in order to support SI investments, the public authorities within SolAqua will produce a SI-suited supporting instrument and will allow for its replication throughout Europe.

Keywords: solar irrigation,sustainable farming,rural development
New sustainable Nature-inclusive architectural devices for the transformation of our interior dwelling space: through selected case studies. (Nature-In)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-08-01
End date: 2023-12-30
Duration (months): 36.0
Total project cost (EUR): 310968.0
EU funding (EUR): 310968.0
Participants: 1
Project status: SIGNED

Nature-In is an interdisciplinary research project that will unfold and analyse the underlying forms of knowledge behind exemplary postwar-Danish and traditional-Japanese buildings which stand out for their interior space connection to Nature, which remains unexplored, to inform us of a sustainable contemporary interior design practice. To maximize the contact with Nature in the health and wellbeing promotion of populations, design strategies are urgently needed. Despite the increasing interest in this global concern, there exists limited knowledge and research into “how to integrate Nature with our dwellings’ interior space”. There is a lack of architectural small-scale solutions for achieving this and also limited research into the ways these solutions can enable their integration. To bridge these gaps, I will conduct a case-study analysis to present the first synthetic overview, revealing what devices are used in these case-studies to link their interior space with the surrounding nature. With the involvement of a network of international experts, a methodology that links architectural research and practice, and a link to my own practice, I will provide a catalogue of potential sustainable practical devices and recommendations for integrating architectural devices of the buildings studied and I will influence researchers, design practitioners, policy-makers and society in building practice. The main aim is to effectively enhance the health and wellbeing of communities through daily interaction with Nature in urban areas of the future, an urgent challenge at EU and Global level. Nature-In is very original and innovative in terms of objectives, how it is conceived and how it will be conducted. It will open a new research branch of Architectural Design and a new phase in the Biophilic Design’s implementation for the built environment. Moreover, it will make an important contribution to the EU-knowledge base on Nature-Based Solutions, a significant step for the EU.

Keywords: building,architecture,architectural design,interior design,design,nature,housing,sustainability,nature based solution,biophilic design,eco design,landscape,health,denmark,europe,japan
THE COLOUR OF LABOUR: THE RACIALIZED LIVES OF MIGRANTS (COLOUR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Portugal
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-09-01
End date: 2023-04-30
Duration (months): 80.0
Total project cost (EUR): 2161397.0
EU funding (EUR): 2161397.0
Participants: 1
Project status: SIGNED

This project is about the racialization of migrant labourers across political boundaries, with a main focus on impoverished Europeans who served in huge numbers as indentured labourers in nineteenth-century Guianese, Caribbean and Hawaiian sugar plantations and in the workforce of late nineteenth and early twentieth century New England cotton mills. With this project I aim to provide major, innovative contributions on three fronts: (i) theory-making, by working the concepts of race, racism, racialization, embodiment and memory in association with migrant work across political boundaries and imperial classifications; (ii) social relevance of basic research, by linking an issue of pressing urgency in contemporary Europe to substantive, broad-scope, and multi-sited anthropological/historical research on the wider structures of domination, rather than to targeted problem-solving research of immediate applicability; (iii) disciplinary scope, by proposing to unsettle historical anthropology and ethnographic history from within the boundaries of a single empire, and to overcome the limitations of existing comparative studies, by inquiring into the flows and interactions between competing empires. I will also: (iv) strengthen the methodology for multi-sited, multi-period research in anthropology; (v) contribute to an anthropology of global connections and trans-local approaches; (vi) promote the multidisciplinary and combined-methods approach to complex subjects; (vii) narrate a poorly known set of historical situations of labour racializations involving Europeans and document the ways they reverberate through generations; and (viii) make the analysis available to both academic audiences and the different communities involved in the research.

Keywords: race,racialization,body,migration,displacement,indentured labour,labour flows,plantations,industrial workers,islanders,ethnographic history,communities,hyphenated identities,memory
Biochemical and mechanochemical mechanisms in polarized cells (BIOPOL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Spain,Italy,Spain,Germany,Germany,Spain,Switzerland,France,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 3911897.16
EU funding (EUR): 3911897.16
Participants: 15
Project status: CLOSED

BIOPOL is an interdisciplinary European training network at the interface of cell biology, physics and engineering. BIOPOL aims specifically at the understanding of fundamental mechanochemical principles guiding cellular behaviour and function and their relevance to human disease. A new supra-disciplinary research field is emerging bringing together the fields of molecular cell biology, physics and engineering aiming at an in depth understanding of fundamental cellular mechanochemical principles. BIOPOL combines exactly this required expertise in one joint training program for young researchers. BIOPOL has assembled a unique multidisciplinary consortium bringing together top scientists from the fields of molecular/developmental cell biology, membrane physics, engineering as well as specialists from the private sector. The scientific objectives focus on understanding of fundamental mechanisms of cellular mechanosensing in health and disease, the role of external forces in cell division and mechanochemical regulation of cell polarity including tissue formation. Finally, part of BIOPOL´s research program is the further development of cutting edge technologies like advanced atomic force microscopy, novel photonic tools like optical stretcher or innovative organ on a chip technology, exploiting physical cellular properties. BIOPOL´s collaborative cutting edge research program is integral part of its training program provided to early stage researcher and is further translated into seven state of the art experimental training stations representing the consortiums expertise. In addition, BIOPOL has developed a 3 years modular curriculum including workshops, summerschools, Business plan competitions and conferences with a specific agenda of transferable skill training elements highly relevant for scientific communication, translational research and in particular entrepreneurship.

Keywords: cell mechanics,membrane trafficking,caveolae,mechanotransduction,endocytosis,planar polarity,actin cortex,cell polarity,signal transduction
Future Improvement for Energy and Noise (FINE 1)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: European rail initiative
Action type: Research and Innovation actions
Partnership: Shift2Rail (Art-187)
Countries involved: Austria,Germany,Germany,Spain,Spain,Germany,Sweden,Sweden,France
Call: Energy and sustainability, including noise and vibrations baselines assessment (H2020-S2RJU-CFM-2015-01-1, 2015)
Start date: 2016-09-01
End date: 2019-10-31
Duration (months): 38.0
Total project cost (EUR): 1340880.0
EU funding (EUR): 1340880.0
Participants: 14
Project status: CLOSED

The FINE 1 project aims to reduce operational costs of railways by a reduction of energy use and noise related to rail traffic. The project results are expected to enable an increase of traffic in Europe and to enhance the attractiveness of railway in relation to other modes of transport. The project activities will support the innovation process within the S2R Technical Demonstrators (TDs) by providing methodology and know-how to enable development of low noise and low energy TDs. The project is fully in line with the EU objectives with eight technical work packages (WPs) addressing technologies to support these objectives. The reduction of energy use for rail vehicles is as addressed in WP 3 and WP4 and will indirectly lead to reduced green-house gas emissions, also with most rail transport powered with electricity. Further, reducing energy use will lower the life cycle cost and the costs of vehicle operation. The project also aims at development of practical methods for predicting noise and vibration performance on system level including both rolling stock, infrastructure and its environment. Prediction of interior vehicle noise is addressed in WP 7 and source modelling for interior and exterior noise in WP 8. With an accurate characterization of each contributing source, it will be possible to optimize cost benefit scenarios, as addressed in WP 6, as well as take exposure and comfort into account. Finally, the auralisation and visualisation techniques of traffic noise scenarios and the noise control techniques developed in WP 9, support the reduction of noise exposure for residents by efficient traffic planning and novel mitigation techniques. In summary, the expected FINE 1 advances of the state-of-the-art in noise modelling and control as well as in energy management and control methodology, will improve the competitiveness of the European railway system compared to other modes of transportation and thus promoting a modal shift to rail.

Keywords: noise emission,energy consumption,environmental noise reduction,sustainability