Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Logic and Learning: an Algebra and Finite-Model-Theory Approach (LLAMA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2025-01-15
Duration (months): 24.0
Total project cost (EUR): 175572.48
EU funding (EUR): 175572.48
Participants: 1
Project status: SIGNED

Computational learning theory is a branch of computer science that studies the mathematical and algorithmic underpinnings of machine learning. It provides the concepts and methods to classify the computational feasibility of different learning problems. This project lies at the intersection of computational learning theory and logic, and it builds on recently identified new connections between learning theory and universal algebra. Its high-level goals are (i) to improve our understanding of learnability for fragments of first-order logic, motivated by applications in data management and knowledge representation, and (ii) to further develop and exploit the recently identified connections with universal algebra (as well as combinatorial graph theory, finite model theory, and fixed point logics), to developing a rich technical framework for proving new results. More concretely, we will study aspects of computational learning theory for fragments of first order logic under constraints (that is, in the presence of a background theory), with applications in data management and knowledge representation.

Keywords: logic,computational learning theory
Microbes in the city: a metagenomic trait-based analysis of microbial metacommunity structure along urbanization gradients (MicroCity)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Belgium
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-01
End date: 2017-09-12
Duration (months): 24.0
Total project cost (EUR): 172800.0
EU funding (EUR): 172800.0
Participants: 1
Project status: CLOSED

Human induced environmental gradients have a strong effect on biodiversity and ecosystem functioning. Despite the valuable ecosystem services (such as biogeochemical cycling and xenobiotic degradation) provided by microbial communities, environmental conservation policies usually neglect microbial diversity. This can be in part attributed to our poor understanding of microbial community responses to anthropogenic influences in natural landscapes. Urban ecosystems are key examples of environments that are strongly impacted by anthropogenic activity. In addition to our need to understand how microbial communities respond to urbanization, urbanization gradients are also excellent model systems to study how the taxonomic and functional diversity and composition of microbial communities respond to anthropogenic stress in general. In the here proposed project, we will study microbial communities in freshwater ponds located across well characterized urbanization gradients in Belgium. We will apply metagenomics in a molecular trait based approach in an effort to determine the influence of human induced environmental gradients on the biogeochemical cycling and xenobiotic degradation pathways in microbial communities. Also, we will analyse the role of the mobilome - mobile genetic elements such as plasmids and transposons - as a source of rapid evolution in microbial communities under anthropogenic stress. We will take a metacommunity approach in order to quantify the relative importance of local (environmental) and regional (spatial) processes in shaping bacterial communities across the studied gradients. Our proposed study is unique as it combines the nascent theory of evolving metacommunities with a high throughput molecular approach, metagenomics, to better understand the impact of urbanization on microbial community structure and function.

Keywords: microbial communities,metagenomics,mobile genetic elements,metacommunities,catabolic pathways
The Tragic Body in the Syrian Context (SYRBODY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-16
End date: 2021-09-15
Duration (months): 24.0
Total project cost (EUR): 167491.2
EU funding (EUR): 167491.2
Participants: 3
Project status: CLOSED

“SYRBODY – The Tragic Body in the Syrian Context” is one of the first attempts to think the consequences that one of the greatest tragedies of our time, the Syrian tragedy, has had on the body. This project aims to develop and disseminate a contextual philosophy of the body by drawing upon psychoanalysis and literature in order to study (1) the mutilations that the body of refugee undergoes, (2) its attempt to resist those mutilations by creating real – but above all imaginary – prosthetics for itself, (3) and its incorporation of dead people, the morning of which is impossible. SYRBODY responds to one of the principal priorities of the Horizon 2020 work program 2018-2020, namely “Migration and the refugee crisis,” insofar as it aims to help understand the life of refugees and, in the same stroke, bring to light the injustice and horror that they are fleeing. SYRBODY proposes to combine fieldwork with Syrian refugees and conceptual and theoretical work. The fieldwork will be conducted mainly in Lebanon, which hosts the largest number of refugees in the Arab world. During the outgoing phase, I will carry out fieldwork in Lebanon in order to establish a solid basis of data concerning three elements: texts, audiovisual products, and interviews. The conceptual and theoretical work will be conducted mainly in France during the incoming phase. This project’s Beneficiary is the Université Paris-Diderot (the Centre d’Etudes et de Recherches Interdisciplinaires en Lettres Arts Cinéma), and its Partner Organization is the Institut Français du Proche-Orient in Beirut.

Keywords: refugees,body,mutilation,prostheses,incorporation
Innovative Fireman's Switch for Photovoltaic Systems: towards large-scale production (INNO PV-SWITCH)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Austria
Call: Accelerating the uptake of nanotechnologies advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-05-01
End date: 2017-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Solar energy is a sustainable and cost-effective electricity source which nowadays significantly contributes to the electricity needs worldwide (1% of the world electricity demand) with a strong growing tendency through the increasing number of photovoltaic (PV) systems (a growth of 80% can be expected in Europe by 2019).However, PV systems present unique electric hazards during (de)installation, maintenance works or in case of fire as it is not possible to immediately cut the power because of DC residual voltages (up to 1.000-1.500 V) present even after switching off. To overcome these problems, the so-called fireman´s switches are installed in order to de-energize the DC conduit. However, existing fireman´s switches in the market have a clear lack of technological appropriateness in order to assure minimum electrical hazards.BENEDICT GmbH, an Austrian SME with large experience in the development of electro-mechanic switches, has developed INNO PV-SWITCH, an innovative fireman´s switch with cutting-edge technical features that minimizes electric hazards in PV systems due to the remote switching on/off and the simultaneous disconnection and short-circuit of the PV panels among other crucial disruptive advantages. INNO PV-SWITCH has a potential market of 9,4 million PV systems in key target countries, accounting for more than 500 million EurosThe minimization of risks associated to photovoltaic systems is a key issue for the European Union in order to propel this Renewable Energy. Moreover, the growing number of PV systems worldwide, together with each time stricter regulations and an increased awareness about security, makes this project a unique, exciting and profitable business opportunity for BENEDICT. Our company expects total revenues of €12,4 million in the first 3 years of commercialization of INNO PV-SWITCH and an associated ROI of 6.

Keywords: photovoltaic systems,dc swichting device,photovoltaic installations
Market Opportunity Validation and Business Plan Development for horticulture research LED solution - HORTILED (HORTILED)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: SME instrument
Countries involved: Lithuania
Call: Stimulating the innovation potential of SMEs for sustainable and competitive agriculture, forestry, agri-food and bio-based sectors (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-07-01
End date: 2016-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Global food system will experience a food security crisis over the next 40 years. Global food production will need to increase by 70% to feed the planet. LEDs have tremendous potential to increase plant and food production, Determining how wavelengths, light level, position and time influence each single plant at the same given moment, can increase yields, quality of products and give better control of plant growth, however, such research in Europe is limited to only several research labs. To address the problem, Energenas, a Lithuanian SME, run by experienced horticulture experts for more than a decade, has launched a novel solution – HORTILED, the most flexible and versatile integrated system of light emitting diodes for plant growth research in controlled environments. The technology is unique in its compact size and ability to be adapted and controlled individually on a small scale. By combining extremely light frame with a control protocol, LED sensors and state-of-the-art software, the Company can offer any researcher the ability to test plant growth and collect data, specifying the ideal growing conditions for plants. Main benefits of HORTILED for researchers: 1) Suitable for various research spaces (growth chambers, phytotrons, laboratories, greenhouses), 2) unique software solution gives possibility to program each spectral component separately and manage their composition during the experiment, and 3) consumes significantly less energy than traditional lighting solutions. HORTILED is currently at TRL6. The next step is moving on to TRL7 - system prototype demonstration in operational environment. For this reason horticulture research market will be analysed and market players identified who will participate in the user needs identification study together with HORTILED’s early access partners, one of which is Wageningen University - the most visible and leading university of agriculture on a global scale.

Keywords: horticulture,research market,food production,growth recipes,plant growth data
Distributed Biological Algorithms (DBA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Israel,France
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-05-01
End date: 2021-04-30
Duration (months): 72.0
Total project cost (EUR): 1894947.0
EU funding (EUR): 1383638.0
Participants: 2
Project status: CLOSED

This project proposes a new application for computational reasoning. More specifically, the purpose of this interdisciplinary project is to demonstrate the usefulness of an algorithmic perspective in studies of complex biological systems. We focus on the domain of collective behavior, and demonstrate the benefits of using techniques from the field of theoretical distributed computing in order to establish algorithmic insights regarding the behavior of biological ensembles. The project includes three related tasks, for which we have already obtained promising preliminary results. Each task contains a purely theoretical algorithmic component as well as one which integrates theoretical algorithmic studies with experiments. Most experiments are strategically designed by the PI based on computational insights, and are physically conducted by experimental biologists that have been carefully chosen by the PI. In turn, experimental outcomes will be theoretically analyzed via an algorithmic perspective. By this integration, we aim at deciphering how a biological individual (such as an ant) “thinks”, without having direct access to the neurological process within its brain, and how such limited individuals assemble into ensembles that appear to be far greater than the sum of their parts. The ultimate vision behind this project is to enable the formation of a new scientific field, called algorithmic biology, that bases biological studies on theoretical algorithmic insights.

Keywords: natural algorithms,algorithmic trade off,communication complexity,stochastic processes,information theory,mobile agents,consensus,applications of mathematics to biology,routing
Understanding the Collective Behaviour of Catalytically-Driven, Self-Propelled Colloids: From Fine-Grained Hydrodynamic Simulations to Effective Field-Theoretical Descriptions (HydroCat)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-11-16
End date: 2017-11-15
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

HydroCat proposes a simulation and theory study into the collective behaviour of catalytically-driven, self-propelled colloids. The first step of the investigation focusses on understanding the mechanism by which platinum-coated Janus particles self-propel on a single-particle level. This will be accomplished by modelling the two candidates for the mechanism, self-diffusiophoresis and self-electrophoresis, and directly comparing the behaviour of the hybrid-model to experimental results. Once sufficient insight has been achieved, the focus of the project will shift to the description of the collective behaviour of these particles. Here, HydroCat follows a three-pronged strategy: (i) development of a finely-resolved lattice-Boltzmann (LB) simulation that takes into account all relevant physical effects and is capable of simulating a large number of particles; (ii) coarse-grained molecular dynamics simulations to study the collective behaviour of these Janus colloids, which are benchmarked against the fine LB simulations; and (iii) a fully coarse-grained, field-theoretical description that uses input from both (i) and (ii). HydroCat will result in an improved understanding of the catalytic self-propulsion, which will serve as a solid foundation for the description of experiments and the development of applications.

Keywords: self propelled,catalytic,hydrodynamic,lattice boltzmann,field theory
Promoting S&T excellence and increasing the innovation capacity of the Transylvanian Institute of Neuroscience (NEUROTWIN)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Germany,Romania,France,United Kingdom
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2021-01-01
End date: 2024-06-30
Duration (months): 42.0
Total project cost (EUR): 799425.0
EU funding (EUR): 799425.0
Participants: 4
Project status: SIGNED

Neuroscience Neuroscience is an advanced field of science still poorly represented in Eastern Europe. Individual efforts have created some centres of excellence over the past years, mostly by scientists returning home from western labs. One such centre is the Transylvanian Institute of Neuroscience (TINS), located in Transylvania, Romania. TINS hosts one of the most important training centres in experimental neurosciences worldwide: the Transylvanian Experimental Neuroscience Summer School (TENSS). We propose a twinning between TINS and three internationally-leading European institutions from countries where neuroscience is most developed: Germany, France, and UK. TINS will twin with the Ernst Stüngmann Institute for Neuroscience in Frankfurt, Imagine Institute in Paris, and University College London. The objectives of the twinning are: i) to increase the scientific competence of TINS researchers; ii) to increase the innovation capacity of TINS; iii) to enhance the international visibility and prestige of TINS; iv) to improve TINS’ capability to compete for research funding; v) to promote the involvement of early stage researchers at TINS; vi) to enable TINS to become a neuroscience development pole in Romania and Eastern Europe. To attain these objectives, TINS and its three top international partners will organize periodically mutual research staff exchanges (short stays), training lectures at each institution, a top profile neuroscience seminar series at TINS, the TENSS summer school, periodic consortium retreats, dissemination and outreach activities with patient associations and industry, and collaboration among technology-transfer offices to implement best practices at TINS. The twinning will increase the scientific competence at TINS in neurosciences, develop a competitive innovation and technology transfer strategy, raise significantly its international visibility, and enable it to successfully partner with top institutions for future collaborative projects.

Keywords: neuroscience,visual system,2 photon imaging,optogenetics,behavior,electrophysiology,tenss,brain,cortex,dynamical systems,neural networks
Improved therapies for soil-transmitted helminthiases: exploring pharmacomicrobiomics, novel drugs and microfluidic assay platforms (DRUGSBUGS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Switzerland
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2022-01-01
End date: 2026-12-31
Duration (months): 60.0
Total project cost (EUR): 2470621.0
EU funding (EUR): 2470621.0
Participants: 1
Project status: SIGNED

An estimated 1.5 billion people are infected with soil-transmitted helminths (STHs) causing a global burden of 1.9 million disability-adjusted life years (DALYs). Current treatment options are limited. Preliminary studies in my lab hint towards a gut microbiome mechanism responsible for treatment failures of the most efficacious treatment currently available, albendazole-ivermectin. I propose an innovative 5-year project (“DRUGSBUGS”) that holds promise for major breakthroughs in anthelminthic drug discovery and development. I will deepen the understanding of current and potentially upcoming anthelminthics, in particular the microbiome-driven modulation of anthelminthic treatment. I will investigate underlying gut microbial structures in human stool samples associated with efficacy of albendazole-ivermectin treatment. Findings will be experimentally validated in vitro and in vivo. In addition, I speculate that emodepside will emerge as a novel key player in the anthelminthic drug armamentarium, which will enhance efficacy and reduce the risk of selection of resistant helminth populations. DRUGSBUGS proposes two Phase 2a dose selection trials with emodepside against Trichuris trichiura and hookworm in adults. Subsequent Phase 2b studies will assess whether emodepside is superior to albendazole against hookworm and T. trichiura. Using a microsampling technique, I will characterize the pharmacokinetics of emodepside in patients infected with T. trichiura and hookworm. In parallel, investing in innovative new technologies in the field of drug discovery will facilitate the discovery and development of the next generation of anthelminthics. I propose to study drug effects on motility and viability of different STH larvae applying electrical impedance spectroscopy on a microfluidic chip platform. My proposed research is of considerable public health relevance since it will ultimately result in improved treatments for soil-transmitted helminthiases.

Keywords: soil transmitted helminthiasis,hookworm,trichuris trichiura,pharmacomicrobiomics,emodepside
Polynuclear Gold Catalysis (GOLDCLUSTER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-06-27
End date: 2018-06-26
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

During the last decade, homogeneous gold catalysis has witnessed rapid growth for C–C bond forming reactions mainly due to the soft carbophilic Lewis acid properties of gold complexes toward C–C triple bonds. Compared to Lewis acids and other transition metals, gold catalysts are very active under mild conditions, can tolerate moisture and oxygen and are compatible with diverse functional groups. Gold catalyzed tandem and multi-component reactions allow the efficient transformation of simple starting materials in complex molecules, which have been used for the synthesis of numerous biologically active targets. GOLDCLUSTER aims at advancing the field of gold chemistry by the development of new superelectrophilic small gold (I) clusters (Au3, Au6 and Au8). These complexes will be used as catalysts in the retro-Büchner reactions of cycloheptatrienes to form in situ gold carbenes, leading to the formation of complex molecules using milder conditions (lower reaction temperature, more efficient catalysts, and better yields). In addition, the new catalysts will also be tested in the catalytic activation of small molecules, such as methane. GOLDCLUSTER will contribute greatly to the advancement of gold chemistry by exploring new directions in the area and providing new tools to further enhance the development of efficient synthetic methods that could be later adapted by the Chemical Industry, making the European economy more competitive and better aligned with the Horizon2020 growth strategy.

Keywords: homogeneous catalysis,gold clusters,retro b chner reactions,gold carbenes,synthetic methods