Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Researchers’ night 2007 of the West part of France : Researchers and ICT (ATLANTIC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: France,France,France,France,France,France
Call:  (FP7-PEOPLE-2007-5-1-1-NIGHT, 2007)
Start date: 2007-05-01
End date: 2007-11-30
Duration (months): 7.0
Total project cost (EUR): 184727.0
EU funding (EUR): 72000.0
Participants: 8
Project status: CLOSED

For the Researchers’ Night 2007, 8 partners in 5 towns of the West part of France (from Bordeaux to Brest) will share their human and scientific richness. Researchers working in universities, research centers as Inserm and scientific, technical and industrial culture centres will be at the core of the events during the evening of the 28th of September 2007, around the theme Researchers and the Information and Communication Technologies. Music and theatre events, offered by researchers themselves, will demonstrate that they are not these “unreachable” persons but in fact people like any other. Meetings with researchers in unusual places will demonstrate that they are accessible, have hobbies, families, help the citizen’s daily life, have a fascinating job. Workshops and night visit of scientific as well as cultural sites will welcome the public. Viewings, discussions and debates will allow anyone to express himself about the image of researchers and their role in our society. In order to make the young public more sensible to the world of the researchers, a drawing competition (Please draw a researcher) will be launched, during the awareness campaign and will be addressed to fundamental, secondary and High artistic schools. In order to illustrate the European participation in the project and allow the large public to better understand the European support in favour of researchers, the European dimension will be pointed out at different stages of the project with the “drawing competition” (awarded at a European level) and with a European stand, which will be set up around informative and promotion functions. Beneficiaries local researchers of European support will be especially involved during the night. A common graphic design will be created during a general assembly of the consortium. This is essential in order to provide a visual homogeneity all around the West part of France (in accordance with the communication campaign towards national and regional media).

Keywords: researchers,night,information and communication technologies,atlantic,west part of france,public
Survey and Prospects of IMP PAN Research (IMP SURVEY)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: International Co-operation
Action type: Coordination and support actions
Countries involved: Poland
Call:  (FP7-REGPOT-2007-2, 2007)
Start date: 2008-07-01
End date: 2009-04-30
Duration (months): 10.0
Total project cost (EUR): 87600.0
EU funding (EUR): 78110.0
Participants: 1
Project status: CLOSED

The Institut has already an established position in the scientific community involved in broadly understood energy conversion in flows, structural mechanics, dynamics of machinery, laser technology and plasma dynamics. The recognized potential of IMP PAN is a good starting point for the involvement in the European Research Area. However, to reach the level of European partners a significant upgrade of present potential is necessary. It is considered as very useful and helpful for IMP PAN to get a critical evaluation of the existing potential by independent specialists and to obtain indications for further development in the corresponding fields of interest. This will help to guide the development of IMPPAN towards the goals recognized in European Community.

Keywords: aeronautic,heat and mass transfer,combustion,energy conversion,structural mechanics,dynamics of machinery,leser technology,aerosoles,plasma mechanics
Latin Philosophy into Hebrew: Intercultural Networks in 13th and 14th Century Europe (LATIN INTO HEBREW)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: The Human Mind and its complexity
Countries involved: Spain
Call:  (ERC-2007-StG, 2007)
Start date: 2008-09-01
End date: 2012-02-29
Duration (months): 42.0
Total project cost (EUR): 511574.0
EU funding (EUR): 511574.0
Participants: 1
Project status: CLOSED

The intercultural networks between Arabic, Christian and Jewish communities of learning during the Middle Ages have played a decisive role in the evolution of Western thought and have helped to shape the European identity. Until now, scholarly research has focused almost exclusively on the transmission of Arabic philosophy and science into Latin. The influence of Latin texts on Jewish thought has been largely neglected. The goal of this project is to study how Latin-Christian texts written at Toledo were received in the Jewish tradition of the 13th and 14th centuries, and to draw an intellectual topography of the intercultural and interreligious networks that extended across Europe. The work will involve the philosophical analysis of various texts together with their translations and reception, showing how the networks between the different religious communities in the Mediterranean can be understood as an attempt to work on a shared philosophical tradition. This tradition provided a common and continuous medium for dialogue between the faiths, based upon a commitment to philosophical reason. Our approach will be combined with historical and philological research on the conditions and methods of transmission and translation of Latin texts into Hebrew. In addition, the project aims at editing and translating some of the Hebrew texts of reference. The project is only possible in a trans-disciplinary research group, for it requires philosophical, historical and philological skills as well as a high degree of familiarity with the different traditions involved.

Keywords: arabic,latin,hebrew,middle ages,intercultural networks,cultural diversity,religion,philosophy,history,philology
Orchestration of instinctive drives (INSTINCTIVE DRIVES)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Physiology, Pathophysiology and Endocrinology
Countries involved: United Kingdom,United Kingdom
Call:  (ERC-2007-StG, 2007)
Start date: 2008-10-01
End date: 2013-09-30
Duration (months): 60.0
Total project cost (EUR): 1299999.0
EU funding (EUR): 1299999.0
Participants: 2
Project status: CLOSED

A major goal of 21st century science is to protect human health from the growing mismatch between ancient behavioural instincts and modern socio-economic reality. This is especially vital for basic instinctive drives such as appetite, which lead to overeating when food is readily available. The resulting obesity is responsible for 100,000s of premature deaths per year in Europe and North America, and this number is rapidly rising. Sleep is another powerful instinct which substantially contributes to premature human death, for example from car accidents caused by tiredness. Thus “self-destructive” behaviours caused by inappropriate activation of feeding and sleep drives take a devastating social and economic toll in developed countries, and there is a huge unmet need for effective therapies in this area. To design these therapies, we need to understand the brain mechanisms of instinctive drives. However, brain circuits regulating appetite and sleep have only been delineated in the past few years, and their principles of operation are poorly understood at present. The broad aim of my newly-established laboratory is to fill this gap in knowledge. To understand neural signals controlling instinctive drives, and their relationship to well-being and disease, the following questions must be answered: 1) how do neurons that control appetite and sleep generate their electrical and chemical signals? ) how do these neurons interact with each other? 3) how are these neurons altered in disorders of energy balance and sleep? Our objective for the next five years is to address these key unknowns by focusing on neurons known to be unequivocally important for normal sleep and appetite, the orexin and MCH neurons of the lateral hypothalamus.

Keywords: appetite,sleep,neurons
High-accuracy models in theoretical chemistry (HIGHACCTC)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Physical and Analytical Chemical sciences
Countries involved: Hungary
Call:  (ERC-2007-StG, 2007)
Start date: 2008-07-01
End date: 2013-06-30
Duration (months): 60.0
Total project cost (EUR): 500000.0
EU funding (EUR): 500000.0
Participants: 1
Project status: CLOSED

Even today, quantum chemical calculations with experimental accuracy are only feasible for small molecules. This statement is especially true if the considered molecule is far from the equilibrium structure, where the overwhelming majority of quantum chemical models break down. The main purpose of this proposal is to develop new quantum chemical methods that are applicable to at least medium-sized molecules and simultaneously provide results sufficiently close to the experimental data and are capable of describing entire potential energy surfaces. The accuracy goal will be achieved through the reduction of the computational cost of high-precision quantum chemical calculations, which are currently practical for molecules of up to 15 atoms. The cost reduction will be accomplished principally by decreasing the number of numerical parameters to be optimized without sacrificing accuracy. To this end, the negligible parameters will be identified and dropped by adopting the corresponding techniques of computer science. The correct behavior of the models for distorted structures will be ensured by developing new approaches that use a linear combination of functions rather than a single function as a starting point for the description of electronic states. Since the programming work associated with the implementation of the proposed schemes is very complex, the project will rely on the automated programming tools previously developed by the proposer. In addition to the outlined challenging tasks, the proposal aims to implement several more straightforward objectives. In particular, the high-accuracy calculations will be extended to molecular properties that are presently not available. Furthermore, the developed methods will be applied to real-life problems, especially in the field of spectroscopy and atmospheric chemistry.

Keywords: high-accuracy quantum chemical methods,medium-sized molecules,automated programming
Visual Impairment and Degeneration: A Road-map for Vision Research within Europe (EUROVISIONNET)

Framework: FP7 — Cooperation
Programme: Health
Destination: Translating research for human health
Action type: Coordination and support actions
Countries involved: Germany,France,Germany,Portugal,Switzerland,Germany,United Kingdom,Belgium
Call:  (FP7-HEALTH-2007-A, 2007)
Start date: 2008-03-01
End date: 2012-02-29
Duration (months): 48.0
Total project cost (EUR): 802606.8
EU funding (EUR): 795211.0
Participants: 10
Project status: CLOSED

The coordination project EuroVisionNet aims to link the research activities and policies of the European vision research community and to overcome the national fragmentation, therewith intends to become an essential “instrument” for vision research in the 21st century. To reach this goal the following 4 objectives will be addressed: (1) scientific integration of European vision research; (2) collaboration between public and private sectors; (3) needs of the European vision community by means of policies and guidelines; (4) improve the communication between researchers, patients and general public.Linking the research activities in visual impairment and degeneration will be to bring together the major scientific actors in this research field from FP5 and FP6. EuroVisionNet will facilitate the exchange of information between participants coming from different disciplines and initiate a strategic discussion for future activities. Workshops on the ageing eye will be held, aiming to establish a global frame of interaction between stakeholders. Attention will be turned to the communication and collaboration between industry and vision research. To improve the contact, decision makers and R&amp;D departments in the industry will be invited to a conference, supporting the dialogue about solutions to reduce isolation of academia from the private sector. Utilizing the leadership of Retina International, patient information will be collected, sorted, translated into national languages and published on a web-based portal. The development and establishment of this unique EuroVisionNet-portal will also be used to support the communication efforts and information exchange between clinicians, researchers involved with EuroVisionNet, industry and general public. The web-based portal will not only reflect the activities of the EuroVisonNet, but also of the whole Vision research community and will represent a crucial point of contact between science, industry and general public.

Keywords: visual impairment,neuro-degeneration,vision research,eye research,consolidating research community,ageing eye,ophthalmology
Fighting Aneurysmal Diseases (FAD)

Framework: FP7 — Cooperation
Programme: Health
Destination: Translating research for human health
Action type: Collaborative project
Countries involved: France,United Kingdom,Belgium,Sweden,Germany,Belgium,Spain,Denmark,Czechia,Netherlands,Iceland,Türkiye,Austria
Call:  (FP7-HEALTH-2007-A, 2007)
Start date: 2008-07-01
End date: 2012-06-30
Duration (months): 48.0
Total project cost (EUR): 14918835.99
EU funding (EUR): 10999936.0
Participants: 15
Project status: CLOSED

Fighting Aneurysmal Diseases (FAD) is a public health in EU, because of the ageing population. In the absence of intervention, aneurysms evolve towards rupture and death. The translational objectives of the project are to accelerate the acquisition of knowledge, and to develop new diagnostic and therapeutic tools for FAD in humans. The project innovates by integrating two different localizations differing in their initial etiologies but similar in their evolution. FAD will be built by pooling existing and new clinical & biological databases in EU. Tissue and cell banks will be constituted. The deliverables will be the standardization of clinical and biological procedures and the recording of all the material available in the consortium. These databases will provide a basis for genetic studies. Pathophysiology of aneurysms will be explored through human tissue and experimental models in transgenic animals, focusing on the role of proteases and their source within diseased tissues. Human databases, genetic & pathophysiological concepts will provide basis for the development of new diagnostic tools: genetic screening, identification of new surrogate markers, validation of candidate markers and discovery of new ones by proteomic approaches; and functional imaging, visualizing in situ various biological activities. These new molecules/cells of interest will be targeted in preclinical therapeutic approaches, using animal models, and by developing clinical trials. The objective of FAD will be achieved through the organization of a consortium, grouping 15 partners, integrating numerous medical and scientific disciplines. The consortium includes academic partners from 10 different EU countries, a Turkish research team, and 3 industrial partners. The acquired scientific and technological knowledges will be disseminated through training sessions, participation in European meetings, communication toward industry, and direct relationships with patient associations.

Keywords: aorta,genomic,proteomic,human database,diagnosis,therapeutic,experimental model.
European Consortium for Anticancer Antibody Development (EUCAAD)

Framework: FP7 — Cooperation
Programme: Health
Destination: Biotechnology, generic tools and medical technologies for human health
Action type: Collaborative project
Countries involved: Sweden,France,Belgium,Germany,Italy,Switzerland,Germany,Italy,Sweden
Call:  (FP7-HEALTH-2007-A, 2007)
Start date: 2008-05-01
End date: 2012-04-30
Duration (months): 48.0
Total project cost (EUR): 7862359.53
EU funding (EUR): 5989862.0
Participants: 9
Project status: CLOSED

Cancer is the second leading cause of death in European countries, and one of the most imminent health problems in the developed world. Innovative, so-called targeted therapies are urgently needed that aim specifically at cancer cells or to cells of the stroma that support tumor growth. The ultimate goal of a targeted therapy is to increase anti-tumor efficacy with lowest possible side effects. Rapid and efficient translation of basic scientific advances into reagents, and targeted molecular leads for preclinical and clinical research and development based on scientific rationales and state-of-the-art technologies, optimally requires an interdisciplinary, collaborative, team-oriented approach. EUCAAD represents a virtual research institute in Europe and consists of 9 research participants including 4 SMEs devoted to the discovery and evaluation of new antibodies for therapy of human cancers. The consortium consists of researchers from SMEs and scientific and clinical centres that have gained international acclaim in this area of research, many of who have worked together in previous EU funded applications e.g. ANGIOSTOP, EUCAPS, ESTDAB and ENACT. Within the consortium there is unique expertise regarding target discovery, target validation, antibody production and initiation of clinical trials. As part of its efforts to translate laboratory research into viable cancer therapies the individual partners has accumulated an extensive portfolio of intellectual property providing a competitive edge to this application. The focus of the grant is the development and evaluation of antibodies against new target structures on tumour cells and blood vessels supplying tumours which are responsible for tumour angiogenesis, progression and metastasis. Collectively, the activities of this consortium can improve the cancer treatment standards in Europe and provide economic benefit to European biotechnology and pharmaceutical research by providing novel immunopharmaceuticals.

Keywords: antibodies,angiogenesis,tumour,cancer,clinical trials,angiomotin,neovascularization,endothelial cells
Hybrid MEG-MRI Imaging System (MEGMRI)

Framework: FP7 — Cooperation
Programme: Health
Destination: Biotechnology, generic tools and medical technologies for human health
Action type: Collaborative project
Countries involved: Finland,France,Sweden,Italy,France,Sweden,Germany,Italy,Italy
Call:  (FP7-HEALTH-2007-A, 2007)
Start date: 2008-05-01
End date: 2012-04-30
Duration (months): 48.0
Total project cost (EUR): 6854083.2
EU funding (EUR): 4865656.0
Participants: 13
Project status: CLOSED

We will develop and validate hybrid magnetoencephalography (MEG) and magnetic resonance imaging (MRI) technology that will allow simultaneous structural (MRI) and functional (MEG) imaging of the human brain. MEG is a non-invasive 3D functional imaging with a high temporal resolution compared to other functional imaging but often suffers from a precise structural localization which will be solved by the dual modality approach of the MEGMRI hybrid scanner. In parallel, low field MRI, a new very promising alternative to conventional high field MRI will provide enhanced image contrast in certain applications, improved geometric accuracy, improve safety (for patient with pacemakers and other implants, for pregnant women, for infants), and reduce costs. These new opportunities are based on recent advances in ultra-sensitive magnetic sensors. Superconducting magnetometers based on quantum interference devices (SQUIDs) have been recently used to provide 2D-MRI images at very low fields by two US teams. In parallel, a new type of magnetometer, called mixed sensor, based on spin electronics devices, has been developed within our consortium and used for low-field NMR. The first part of the project will be focused on sensor optimization, and low-field MRI development. This covers the development of field-tolerant SQUIDs and optimized mixed sensors and 3D-MRI low-field hardware and software development. The second part of the project will be devoted to a prototype building with the best kind of sensor and extensive preclinical validation, covering major brain disorders for adults and children. The consortium of MEGMRI has the necessary skills to perform all the tasks: sensor developers, MRI experts, MEG developers and clinical validators. It contains 13 partners from 5 countries including 3 SMEs and one large medical device manufacturer.

Keywords: magnetoencephalography,magnetic resonance imaging,squid,mixed sensor,brain imaging,neuroimaging,brain mapping,diagnostics,neuroscience,neurophysiology
Strategies TO Prevent Pregnancy-Associated Malaria (STOPPAM)

Framework: FP7 — Cooperation
Programme: Health
Destination: Translating research for human health
Action type: Collaborative project
Countries involved: France,Denmark,Netherlands,Benin,Tanzania, United Republic of,France,Sweden
Call:  (FP7-HEALTH-2007-A, 2007)
Start date: 2008-02-01
End date: 2011-07-31
Duration (months): 42.0
Total project cost (EUR): 3935026.4
EU funding (EUR): 2997918.0
Participants: 7
Project status: CLOSED

The Partners propose to conduct a cohort study in pregnant women and their newborns to quantify the effects of Pregnancy-Associated Malaria (PAM) and to identify a PAM vaccine candidate. Effects of PAM on the pregnant woman (placental infection and anaemia), the offspring (birth weight reduction), and the infant (increased morbidity and mortality) are well known. Studies underlined the role of P. falciparum variable surface antigens expressed on infected erythrocytes in binding to placenta. A specific immune response against this antigen reduces the effect of PAM during latter pregnancies, making possible to develop a new preventive strategy based on the enhancement of this specific response. This goal will be achieved through cohort studies in 2 endemic areas (West and East Africa), as the mechanisms and the resulting effects may vary with transmission. Biological samples will be collected during pregnancy and infancy to dissect the pathological and immune mechanisms involved, as well as to characterize phenotypically and genetically the infecting parasites, providing a structural basis for anti-PAM vaccine design. The immunopathological effects will be measured in the mothers, their newborns, and the infant, in relation with timing of infection. The ultimate goal is to identify the most immunogenic epitopes of VAR2CSA (the major variable surface antigens of P. falciparum parasites infecting the pregnant women) to be included in such a vaccine. It is anticipated that the product of this project will be directly usable to enter in the pipeline of vaccine development. The 7 Partners of the consortium (5 from 4 EU countries, and 2 from Benin and Tanzania) have a combined history of high class, internationally-recognized research in malaria. All EU teams have huge experience of collaboration with malaria endemic countries institutions and with studies related to malaria in pregnant women, that are also routinely conducted by the 2 African Partners.

Keywords: pregnancy,malaria,inflammation,var2csa,immunology