Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Empowered Participation through Ideating Cultural Worlds and Environments: youth imagining, creating and exchanging cultural values and heritage through game-making (EPIC-WE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Denmark,Portugal,Belgium,Netherlands,Italy
Call: Games and culture shaping our society (HORIZON-CL2-2022-HERITAGE-01, 2022)
Start date: 2023-03-01
End date: 2026-02-28
Duration (months): 36.0
Total project cost (EUR): 3072828.75
EU funding (EUR): 3072828.75
Participants: 12
Project status: SIGNED

EPIC-WE introduces cultural game jams, culture- and value-sensitive game-making and games through and for culture as a novel approach to empower young people as co-creators of European culture and shapers of their own futures in society, cultural institutions (CHIs) and creative industries (CIs). The backbone of the project is the EPIC-WE helix ecosystem - a transferable framework where youth, CHIs, CIs and higher education institutions (HEIs) cooperate as actors in the ecosystem. Together EPIC-WE engage in cultural games jams to create games through and for culture inspired by cultural heritage. The framework explores the potentials of this approach as a method for strengthening European values, belonging and cultural participation. Through game-making activities, EPIC-WE will equip youth with cultural-creative imagination and competencies to face societal challenges with curiosity, creativity, agency and imagination – what we call Empowered Participation. The project is carried out as an ambitious Design-Based Research and Innovation (DBR) action across three European sites, where EPIC-WE ecosystem actors co-create, and through this, develop, implement and evaluate the proposed framework. The validated DBR innovations are presented as accessible resources that enable organisations across Europe to replicate the EPIC-WE ecosystem, formats, and methods. Through extensive research, capacity building and policy advocacy activities, EPIC-WE will ensure that the project’s results reach a wide range of European CHI, CI and HEI actors, including the game industry, civil society organizations and youth. The consortium is in itself a helix ecosystem, bringing together leading research, cultural and creative sector organisations with multidisciplinary excellence in DBR, participatory and value-sensitive design, game design and youth engagement to empower youth as future culture-makers and game-makers in CHIs, CCIs and HEIs and as value-sensitive agents of change in society.

Keywords: games,game jams,youth,empowered engagement,cultural heritage,creative industries,quadruple helix,design based research,game making,value sensitive games,culture sensitive games,game industry
INnovative risk Stratification of heart faIlure throuGH explainable machine learning and compuTational modeling of Left Ventricle (INSIGHT-LV)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 193643.28
EU funding (EUR): 193643.28
Participants: 1
Project status: SIGNED

INSIGHT-LV aims to improve cardiovascular risk prediction by enhancing the evaluation of left ventricle function using multimodal methods. Heart failure (HF) affects over 26 million people globally, with high healthcare costs and hospitalization rates. Current diagnostic tools often fail to accurately predict adverse events, highlighting the need for more effective risk prediction models that integrate diverse clinical data. INSIGHT-LV focuses on two high-risk HF groups: hypertrophic cardiomyopathy (HCM) and COVID-19 patients. HCM, a major cause of sudden cardiac death in young people, lacks updated guidelines and relies on limited predictors. COVID-19 patients show significant cardiovascular risks, creating an urgent need for better risk stratification tools. These two groups represent a substantial part of the HF population requiring improved stratification. The project will provide clinicians with tools to deliver optimized, cost-effective treatment strategies. By characterizing and stratifying HCM and COVID-19 patients, INSIGHT-LV aims to personalize decision-making and advance disease understanding. Using computational modeling, AI, machine learning, and advanced signal and image processing, the project will integrate multimodal datasets, including ECGs, MRIs, genetic tests, and echocardiography, ensuring robust clinical solutions. INSIGHT-LV will test AI models on real-world data to validate improvements in predicting risks such as sudden cardiac death and arrhythmias. This work will set new standards for cardiovascular diagnostics, delivering scientific, societal, and economic benefits.

Keywords: cardiovascular risk quantification,digital biomarkers,artificial intelligence in medicine,machine learning,in silico models,hypertrophic cardiomyopathy,covid 19
Democratizing Machine Learning for Big Series (DEMABIS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-02-29
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Shapelets is the first state-of-the-art Data Series Management System. A Machine Learning platform that empowers users to obtain invaluable insights from their time series data in a way that no other tool or platform in the market does. Our innovation comes not only from a holistic and unique approach to time series data management but also from the implementation of recently discovered novel algorithms for time series data. We are a 100% private owned company focused on R&D. We have a cohesive and highly-skilled team, where half of the employees know each other from a previous company and where leadership and management excel from a technical and business point of view. We are currently 7 people and plan to hire an average of 11 people each year to reach 52 by the end of 2023. Our main verticals and use cases are in the following sectors: Energy, Industrial IoT, Aerospace, Automotive, Health, Sports and Financial. The major market barrier now is to reach critical mass with Shapelets as quickly as possible — a necessity for us given the novelty behind the idea. Our investment plan for for this market opportunity involves obtaining €2M from VCs in 2019 and a another €2M from VCs in 2020. With this funding we will be able to grow our team fast enough to launch the first full and free version of our product, promote our open-source platform so it becomes a standard for time-series analysis and continue building the different industry verticals. We project to triple our revenue to 1.4€M in 2021 and double it in 2022 and 2023. We expect to start making profits from this project by the end of 2021 and a net income is projected to reach €1.15M in 2022 as sales increase and operations become more efficient. With this funding application we pretend to generate a feasibility study to get a grip on the R&D, technical feasibility and commercial potential of our disruptive technology in order to capture this into a business plan for scaling it up.

Keywords: time series,big data
Grounding RRI Actions to Achieve Institutional Change in European Research Funding and Performing Organisations (GRACE)

Framework: Horizon 2020 — Science with and for Society
Programme: Develop the governance for the advancement of responsible research and innovation by all stakeholders, which is sensitive to society needs and demands and promote an ethics framework for research and innovation
Action type: Coordination and support actions
Countries involved: Italy,Spain,Italy,Belgium,Greece,Slovenia,Sweden,France,Netherlands,Denmark
Call: Grounding RRI practices in research and innovation funding and performing organisations (H2020-SwafS-2018-1, 2018)
Start date: 2019-01-01
End date: 2021-12-31
Duration (months): 36.0
Total project cost (EUR): 1499965.0
EU funding (EUR): 1499965.0
Participants: 10
Project status: CLOSED

GRACE aims to contribute to the EC objective of spreading and embedding Responsible Research and Innovation in the European Research Area through the development of a set of SMART (Specific, Measurable, Achievable, Realistic, Time-bound) Grounding Actions (GAs) in six RFPOs leading to fundamental RRI-oriented institutional changes during the project. For each RFPO, the GAs will be incorporated in a 8-year long “Roadmap towards RRI” to set a solid platform for attaining further institutional changes during the ‘after GRACE’ 5 year of the roadmap. The project will develop in a co-creating environment, via an intense mutual learning programme including the 6 partners implementing the GAs (implementing organisations) and the 4 partners assisting with their comprehensive expertise on RRI (co-operating organisations). A suited evaluation and impact assessment scheme will be developed to oversee and monitor the project processes and impacts, applying MoRRI and SDGs indicators, and SwafS KPIs. The project will consist of 1, Preparatory phase (M1-M10) designing the GAs and defining the six Roadmaps for the implementing organizations; 2, Development and mutual learning phase (M11-M34) where the GAs will be implemented; and 3, Stocktaking phase (M30-M36) ensuring the long-term (after project) sustainability of GAs and the preparation of a Guidance to support the implementing organization to successfully pursue the work outlined in the Roadmaps. A well-substantiated management system, and set of communication and dissemination activities will ensure smooth project implementation. GRACE is composed of 8 WPs: WP1 Ethics; WP2 Management; WP3 Governance and mutual learning; WP4-5-6 GAs related to citizen engagement in science, science education and open access, and gender equality, research ethics and integrity, respectively; WP7 Evaluation and Impact Assessment of GAs; WP8 Outreach, communication, dissemination and exploitation. The project involves 10 partners from 9 EC member states.

Keywords: open science,open innovation,institutional change,quadrupole helix,gender,public engagement,education,ethics,integrity,open access
City Lab Education And Research Doctoral Programme (CLEAR-Doc)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Doctoral programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: France
Call: Co-funding of regional, national and international programmes (H2020-MSCA-COFUND-2020, 2020)
Start date: 2022-04-01
End date: 2027-03-31
Duration (months): 60.0
Total project cost (EUR): 4881600.0
EU funding (EUR): 2440800.0
Participants: 1
Project status: SIGNED

The 5-year CLEAR-Doc project aims at attracting PhD students (ESR) from around the world, in order to strengthen their research capacity and soft skills through high standards and fair selection. The trainees will benefit from a unique research environment of excellence thanks to 22 research labs focusing on Urban Research, so as to create the “City of tomorrow”. ESRs will contribute to address major societal challenges in climate-neutral, resource-efficient, resilient, safe and smart cities. The programme includes a choice among 6 interdisciplinary curricula in addition to a mandatory secondment among a comprehensive network of academic, non-academic and international partners of Université Gustave Eiffel, as a means to facilitate professional integration and international experience. In the context of booming urbanization, the richness of the research options offered is expected to meet the most demanding career plans of ESRs in terms of interdisciplinarity, intersectorality and international experience. The project strengths rely on unique excellent competences and experimental platforms available on each of the 7 university campuses as well as historical strong local cooperation with regional and private partners, with the support of European and international networks. The programme originality is to introduce interdisciplinarity and intersectorality from the start, promoting an approach through three cross-disciplinary challenges shared at international level. These challenges are as follows :1-Design and develop resource-efficient urban spaces; 2- Understand and manage ʺurban risks" for safe and resilient cities; 3-Develop the digital city and turn it into a catalyst for social, environmental and economic performance. The CLEAR Doc programme will also provide to the ESRs cohorts the opportunity to work together and within a scientific community and take full advantage of such environment.

Keywords: doctoral programme,urban space,city of tomorrow,urban risks and resilience,digital city,sustainable cities,resource efficient city
Stand-alone power supply saving low-speed fluid energy available around us (Free power supply)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: France
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2014, 2014)
Start date: 2014-12-01
End date: 2015-04-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The project is about designing, manufacturing and marketing a range of stand-alone power supply products based on pico-turbines able to efficiently produce on-line and deliver the few tens to hundreds of watts needed by the process and quality control equipment of the water supply networks. Indeed, so as to limit the Non-Revenue Water (35% NRW in average worldwide ) and to reach the expected service quality, sensors as well as regulation systems and signal transmitters are increasingly installed at the innumerable junctions of the water distribution networks. Beyond those needs, there are several similar industrial stand-alone power needs which can be fulfilled by our breakthrough technology, like for industrial fishing monitoring equipment, irrigation monitoring systems, sailboat on-board safety and comfort equipment or weather marine station and buoy networks equipment, all being of global reach. Thanks to its partnerships with public research labs (Polytechnique Grenoble, CNRS) and experts (Prof. M. Jufer, EPF Lausanne), as well as 3 years of technical development, Save Innovations designed its first innovating pico-turbine, which is intrinsically waterproof, simple (5 main components), requires no specific maintenance and produce at flow speed as low as 0.5m/s. 4 Patents are published, and 5 new patents have been applied. A first set of prototypes have been successfully tested in a relevant environment. Feasibility within the breadth of the water network requirements as well as product range analysis is now needed before heading to the standard product development and industrialization (will trigger a phase-2 request)

Keywords: power supply,stand alone,pico turbine,low speed,immersed,low maintenance,high efficiency,on line mounting,monitoring equipment,water supply network,renewable energy
Dissection of the mammalian transcription termination mechanism by CRISPRi technology. (dCas9)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-08-01
End date: 2019-07-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

RNA polymerase II (RNAPII) transcribes protein-coding genes in eukaryotes. The proper RNAPII transcription termination is crucial for generation of functional mRNAs, and then proteins. Termination, or stop of RNA synthesis, may occur before or after mRNA 3’-end cleavage and polyadenylation. In the last decade many details have been acquired about mRNA maturation, but still little is known about the termination per se. In this proposal I will redress this problem. One of the proposed transcription termination triggers is RNAPII elongation complex pausing downstream of mRNA maturation signal. I will test this hypothesis, using sequence-specific protein binding in the living cells. In the proposed project I will combine cutting-edge CRISPRi/dCas9 technology with classical molecular biology, high-throughput sequencing and computational biology. This approach will allow me to address my research objectives: (1) to elucidate the role of elongation complex pausing in transcription termination and (2) to characterise the induced pausing in terms of stress-resistance. Also by implementation of this project I will develop a bioengineering tool to induce elongation complex pausing. This timely approach, taking advantage of innovative technologies, will allow me to elucidate previously unknown details of RNAPII transcription termination in mammals and expand our knowledge about this process. Importantly, my approach will allow studies on the chromosomal genes in the living cells, making the results unique and valuable. Implementation of the proposed project will enhance my proficiency by improving and diversifying my skills in experimental and computational science as well as boosting my transferable skills, such as scientific communication and writing, project management and networking. This altogether will improve my competitiveness and potential on the way to independent career. Thus the proposal corresponds well with the aims of the Work Programme.

Keywords: rnapii,transcription termination,protein coding genes,mrna
Investigating fibROmuscular dysplasia and spontaneous coronary Artery dissection using genetic and functionaL genomics to decipher the origIN of two female specific cardiovascular Diseases (ROSALIND)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: France
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-03-01
End date: 2023-02-28
Duration (months): 72.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: CLOSED

Cardiovascular disease (CVD) is under-diagnosed and under-investigated specifically in women. Clinical presentation of CVD is often different in women and the aetiology of some diseases is potentially triggered by specific female sex environmental factors (e.g hormonal cycles and pregnancy) and could result in a distinct physiopathology from men. This may apply to fibromuscular dysplasia (FMD) and spontaneous coronary artery dissection (SCAD), two devastating arterial diseases that share clinical features, which are non-atherosclerotic stenosis of medium-size arteries (renal and/or cerebrovascular arteries in FMD, coronary artery in SCAD) and an age of onset under 50, in addition to a high proportion of female patients (75-90%). In addition, genetic predisposing factors may interact with the female specific context and disturb the artery structure and/or function resulting in a female specific propensity to these CVDs. The ROSALIND project aims to: 1) Decipher the genetic basis of FMD and SCAD using genome-wide association in case control cohorts; 2) Examine the functional significance of the genetic susceptibility variants at confirmed loci and their targeted genes using high throughput NGS-based genomic methods and 3) explore the link of genes in FMD susceptibility loci with vascular function by the analyses of engineered cell lines and total expression in human renal arteries . This project will provide an unprecedented resource of genetic, gene expression and functional genomics data that will be instrumental to guide the uncovering of new genes and mechanisms involved in FMD and SCAD. This project will help better understand the physiopathology and shed light on novel and promising therapeutic targets for the non-atherosclerotic arterial stenosis that characterize these female CVDs

Keywords: genome wide association study,fibromuscular dysplasia,non atherosclerotic artery stenosis,women s cardiovascular health
Development of lamella type of wind turbine made of bio composite polymers (ECO-TURBINE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Slovenia,Slovenia
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-06-01
End date: 2016-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

Conventional wind turbines are dangerous for birds, animals and humans in their vicinity and produce harmful low frequency noise; they are made of composites with a considerable carbon footprint. In the project we will provide the first true ecological wind turbine in the world! The realization of the project will place on the market new paradigms in the world of small wind turbines in several ways and will fulfill the following objectives: New material: ECO-TURBINE turbine aerodynamic parts will be made with the revolutionary advanced technology of flax based bio composites and natural based adhesives with 70% less carbon foot print than conventional composites. New technical concept: ECO-TURBINE turbines will have completely new type of movement than conventional HAWT and VAWT wind turbines. Instead of rotational movement of propellers on round surface our solution has a lamella type rectangular »wall« of series of blades. New business/marketing model: ECO-TURBINE turbine will use technical concept of special under angle painted wind turbine as revolving advertising billboard, therefore our solution will be sold primarily as a very effective advertising billboard with additional function of eco and effective electricity generation. New possibility of placement: ECO-TURBINE turbines will be possible to place on areas where conventional turbines could not be placed due to danger (impact and low frequency pollution) to birds and humans or for aesthetic reasons. New revolutionary mechanical principle represent also a huge technological and business opportunity for use in the in hydro power generation for small hydro power plants in rivers and streams with low hydro flow. Patented ECO-TURBINE turbine solution represents a completely new concept that means third basic concept of wind turbines apart from HAWT and VAWT turbines and present attractive business opportunity. With feasibility study will be examined key areas needed for realization of the project.

Keywords: wind turbine,biopolymers,flax,energy efficiency,polymeres,wind energy