Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Managing Risks of Nanoparticles (MARINA)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Nanosciences and Nanotechnologies
Action type: Collaborative project
Countries involved: United Kingdom,Germany,Denmark,Germany,France,Germany,Switzerland,Finland,Germany,Germany,Sweden,Italy,France,Spain,European organisations area,Belgium,United Kingdom,Netherlands,Netherlands,Netherlands,Austria,Ireland,United Kingdom,Austria,Denmark,Sweden,China,Russian Federation,United Kingdom,United Kingdom,Germany,Poland,Belgium,Japan
Call:  (FP7-NMP-2010-LARGE-4, 2010)
Start date: 2011-11-01
End date: 2015-10-31
Duration (months): 48.0
Total project cost (EUR): 12481840.1
EU funding (EUR): 8999924.0
Participants: 51
Project status: CLOSED

While there are standard procedures for product life cycle analysis, exposure, hazard, and risk assessment for traditional chemicals, is not yet clear how these procedures need to be modified to address all the novel properties of nanomaterials. There is a need to develop specific reference methods for all the main steps in managing the potential risk of ENM. The aim of MARINA is to develop such methods. MARINA will address the four central themes in the risk management paradigm for ENM: Materials, Exposure, Hazard and Risk. The methods developed by MARINA will be (i) based on beyond-state-of-the-art understanding of the properties, interaction and fate of ENM in relation to human health and the quality of the environment and will either (ii) be newly developed or adapted from existing ones but ultimately, they will be compared/validated and harmonised/standardised as reference methods for managing the risk of ENM. MARINA will develop a strategy for Risk Management including monitoring systems and measures for minimising massive exposure via explosion or environmental spillage.

Keywords: test validation,true exposure,risk assessment,risk management,integrated test systems (its),monitoring,accident handling.
A new, ground based data-assimilative modeling of the Earth's plasmasphere - a critical contribution to Radiation Belt modeling for Space Weather purposes (PLASMON)

Framework: FP7 — Cooperation
Programme: Space
Destination: Strengthening the foundations of Space science and technology
Action type: Collaborative project
Countries involved: Hungary,United Kingdom,Italy,Finland,New Zealand,South Africa,United States,Poland
Call:  (FP7-SPACE-2010-1, 2010)
Start date: 2011-02-01
End date: 2014-07-31
Duration (months): 42.0
Total project cost (EUR): 2626262.8
EU funding (EUR): 1972049.75
Participants: 12
Project status: CLOSED

The security of space assets are affected by the high-energy charged particle environment in the radiation belts. The controlling principal source and loss mechanisms in the radiation belts are not yet completely understood. During a geomagnetic storm the length of time during which space assets are in danger is determined by the loss mechanisms, particularly by relativistic electron precipitation. The primary mechanism for this precipitation is the interaction of several wave modes with resonant electrons which leads to scattering into the atmospheric loss cone. The nature of the wave activity and the interactions between the waves and radiation belt particles are strongly governed by the properties of the plasmasphere. At this point there are few existing and regular measurements of plasmaspheric properties, with existing plasmaspheric models lacking the structures known to exist in the real plasmasphere. There is evidence that enhanced wave activity and enhanced radiation belt losses occur due to such structures. In addition, there are large uncertainties concerning the fundamental nature of relativistic electron precipitation (REP), due to the difficulties of undertaking quality in-situ measurements. To address these uncertainties in this proposed project we will provide regular longitudinally-resolved measurements plasmaspheric electron and mass densities and hence monitor the changing composition of the plasmasphere, one of the properties which determines wave growth. This will allow us to develop a data assimilative model of the plasmasphere. At the same time, we will monitor the occurrence and properties of REP, tying the time-resolved loss of relativistic electrons to the dynamic plasmasphere observations. Our approach will primarily use ground-based networks of observing stations, operating in the ULF and VLF ranges, deployed on a worldwide level. Our proposal is made up of 6 work packages to meet these science goals.

Keywords: plasmasphere,radiation belts,whistler,flr,relativistic electron precipitation,vlf,ulf,modeling
Old Pious Vernacular Successes: best-selling vernacular religious literature in medieval Europe (1230-1450) (OPVS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: The study of the human past
Countries involved: France
Call:  (ERC-2010-StG_20091209, 2010)
Start date: 2010-11-01
End date: 2016-04-30
Duration (months): 66.0
Total project cost (EUR): 1234072.0
EU funding (EUR): 1234072.0
Participants: 3
Project status: CLOSED

The OPVS project challenges previous studies by resorting to the medieval readers perspective in order to rank medieval Europe s bestselling vernacular religious texts: we shall focus on successful texts with voluminous manuscript traditions, taking into account the most popular ones, extant in over 60 copies. All were written (or translated) in French, English or German: texts composed in other vernacular languages were not so widely disseminated. These manuscripts will bear testimony as to how, when and where they were produced. Because they have traces of their owners and have been annotated by medieval readers, they can also yield new data on medieval pious practices and religious reading. Previous studies have generally eschewed this documentary evidence, except in the case of deluxe copies. This neglect is due both to a greater interest for Latin treatises with lofty ambitions, and to the impossible challenge, for a single researcher, of dealing with multiple manuscripts, kept in libraries worldwide hence the need for new investigating methods and teamwork. Our project s novel perspective consists in studying these manuscripts both individually and comparatively, combining a traditional erudite approach and new serial methods (quantitative codicology). Relying on an innovative database, our aim is a) to develop a sophisticated typology of medieval religious manuscripts in vernacular languages, b) to determine when, where and in which milieus the selected texts were copied and circulated, giving new insights into all the agents involved in the European book trade of religious literature in vernacular languages especially workshops and book owners, and finally c) to produce comparative studies of medieval literacy and readership in France, England and Germany.

Keywords: european religious culture,written culture,readership,manuscripts,vernacular languages
High Resolution Freshwater Monitoring: FreshMon GMES Downstream Services (FRESHMON)

Framework: FP7 — Cooperation
Programme: Space
Destination: Space-based applications at the service of the European Society
Action type: Collaborative project
Countries involved: Germany,Germany,Netherlands,Finland,Switzerland
Call:  (FP7-SPACE-2010-1, 2010)
Start date: 2010-12-01
End date: 2013-11-30
Duration (months): 36.0
Total project cost (EUR): 2714300.0
EU funding (EUR): 2155367.4
Participants: 5
Project status: CLOSED

In-land aquatic systems are under significant pressure from agriculture, economical development and climate change. EU water policy consists of several European directives; most important the Water Framework Directive (WFD) to sustain aquatic ecosystems. Monitoring programmes have been defined that require a coherent and comprehensive overview about the water status within each river basin and lake district, i.e. continuous and frequent high resolution water quality map products are required. Earth Observation (EO) products improve the capability for harmonized monitoring of water constituents at catchment scale, indicating impacts on water quality and changes within the aquatic ecosystem directly. The FRESHMON consortium will develop a new service-line for the frequent provision of Earth Observation based products for water quality monitoring, combining in situ and hydrodynamic modelling components and integrating the information in a GIS,. The users targeted by FRESHMON are international, national and state-wide authorities, who have a mandate for coordinating the implementation of the WFD. Additional users are national and international private entities, who are dealing with water quality and related issues. By providing high-resolution spatial geo-information on water quality parameters a wide group of user needs is addressed, that cannot be satisfied by existing GMES Core services. The main objective is to create continuous and well accepted downstream services for inland water monitoring at European level, through: * methodological research in improving and harmonizing different EO-based methodologies for retrieving water constituents and water depth * establishment of validation and quality management standards with end users * providing customization, confidence and acceptance of EO products for end users * establishment of a European business network of Downstream inland water service providers and end-users

Keywords: gmes,downstream,earth observation,sme,remote sensing,lake,river,environment,space,core,service,geo-information,geoland2,wfd,europe,water,directive
Targeting Hernia Operation Using Sustainable Resources and Green Nanotechnologies. An Integrated Pan-European Approach (GREEN NANO-MESH)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Nanosciences and Nanotechnologies
Action type: Collaborative project
Countries involved: Ireland,Israel,Spain,Denmark,Belgium,Belgium,France,Germany
Call:  (FP7-NMP-2010-SMALL-4, 2010)
Start date: 2011-06-01
End date: 2015-05-31
Duration (months): 48.0
Total project cost (EUR): 3617820.2
EU funding (EUR): 2692666.0
Participants: 11
Project status: CLOSED

Hernia operations are among the most common surgical procedures performed today with over 20 million cases annually worldwide. Hernia incidents are associated with pain and poor quality-of-life for the patient and lead to enormous healthcare costs, exceeding US $48 billion in the US annually. At present, hernia operations rely heavily on non-degradable polypropylene, polytetrafluoroethylene and nylon meshes. However, these polymers are often associated with foreign body reaction; implant failure; and hernia reoccurrence (over 42%). Moreover, leaking chemicals of these polymers are often deleterious to the surrounding cells and tissue and immobilise post-operative drug treatments. In addition, the process technologies are often associated with environmental risks. Herein, we propose a novel approach that employs recent advances in green nanotechnology and sustainable raw materials for scaffold fabrication that not only will eliminate toxic chemicals from the processes, but will also enhance functional repair due to superior biological properties. Specifically, we aim to fabricate a nano-fibrous mesh with well-defined nano-topography using cellulose; human recombinant collagen, derived from transgenic tobacco plants; and biodegradable polylactic/polyglycolic acid as raw materials. The green credentials of this innovative approach lie in the use of sustainable eco-friendly raw materials that will produce biodegradable waste products and therefore replacing hazardous chemicals currently in use. Thus, this proposal directly fits the call for the substitution of materials or components with ‘green nano-technology’.
Institutional Frictions in International Finance and Asset Pricing (IFAP)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Individuals, institutions and markets
Countries involved: United Kingdom
Call:  (ERC-2010-StG_20091209, 2010)
Start date: 2010-11-01
End date: 2016-10-31
Duration (months): 72.0
Total project cost (EUR): 925910.0
EU funding (EUR): 925910.0
Participants: 1
Project status: CLOSED

My project consists of three lines of work. 1. Incentives of Money Managers and Asset Pricing The leading theories of asset pricing stipulate that prices in financial markets are determined by households who seek to optimise lifetime consumption (or by the so-called representative consumer ). This approach leaves no role for important institutional frictions such as, e.g., financial constraints and contract-induced incentives that played a major role in the 2008 crisis. An analysis of such frictions will add vastly to our understanding of how institutions make decisions and will also allow us to explore the implications of these decisions for asset prices. I propose to depart from the representative agent paradigm and introduce explicitly institutional investors into asset-pricing models. My goal is to understand how institutions affect financial markets and the real economy and to help develop appropriate policy responses. 2. International macro-finance In the past two decades, economic globalisation has produced an unprecedented rise in cross-border equity holdings. Accounting for capital gains on these equity holdings, currently disregarded both in the official statistics and in traditional international macroeconomics, may potentially overturn implications and policy recommendations of the leading theories. In this project, I seek to enrich the field by incorporating explicitly portfolio choice and capital gains on financial assets. Such a theory marries two fields of research: international economics (Economics) and asset pricing (Finance). 3. Combining the above two areas The 2008 crisis was sparked by banks and lead to a worldwide recession. Combining the insights from the first two projects, I intend to research how the instability spreads across countries and how incentives of institutions ought to be designed to limit the consequences of their actions for asset values and the real economy.

Keywords: asset pricing,institutions,frictions,money management,international macro-finance,capital gains,portfolio models,current account,contagion.
From Sedentism to Proto-Urban Societies in Western Anatolia (PREHISTORIC ANATOLIA)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: The study of the human past
Countries involved: Austria
Call:  (ERC-2010-StG_20091209, 2010)
Start date: 2011-07-01
End date: 2016-06-30
Duration (months): 60.0
Total project cost (EUR): 1256428.0
EU funding (EUR): 1256428.0
Participants: 2
Project status: CLOSED

Prehistoric archaeology in western Anatolia has been poorly pursued since the beginning of excavations in this area in the 19th century. Especially the central coast between Pergamon and Ephesos represents a terra incognita in most prehistoric periods of humankind. The project focuses mainly on two distinctive chronological and cultural horizons the period of the first permanent settlements (sedentism) in Neolithic and the development to proto-urban centres in Early Bronze Age period. Combining both huge research topics in one project would enable a broad spectrum of cultural modelling, based upon multidisciplinary diachronic and comparative studies concerning changing societies in a changing environment from the 7th to 3rd millennium BC. New archaeological excavations as well as environmental surveys in different micro-regions (Pergamon and Ephesos) are the essential methods to produce modern documented data that will be analysed with a broad multidisciplinary and international team of scientists and students. Besides archaeology, those disciplines are geophysics, paleogeography, metallurgy, inorganic chemistry, petrography/mineralogy, geology, zoology, botany, anthracology, organic chemistry, physics and anthropology. To achieve an integrated picture and to concentrate the broad spectrum of studies a focus on the following three research topics is proposed: 1. Archaeological Periods and Definitions of Cultures 2. Societies in Changing Environments 3. Communication, Exchange and Interregional Relationships. The applicant has already performed investigations in these highly promising regions and could thereby successfully demonstrate a great gain in knowledge of basic cultural developments of humankind in prehistory.

Keywords: changing environment,subsistence strategies
Space Weather Integrated Forecasting Framework (SWIFF)

Framework: FP7 — Cooperation
Programme: Space
Destination: Strengthening the foundations of Space science and technology
Action type: Collaborative project
Countries involved: Belgium,Belgium,Italy,Denmark,Czechia,United Kingdom
Call:  (FP7-SPACE-2010-1, 2010)
Start date: 2011-02-01
End date: 2014-01-31
Duration (months): 36.0
Total project cost (EUR): 1991474.08
EU funding (EUR): 1559005.56
Participants: 7
Project status: CLOSED

We address two fundamental issues in space weather: 1) development of a integrated framework for the physics modelling of space weather, 2) study of methods and software to address the linkage (coupling) between different physics and processes developing simultaneously or in cascade. We propose a plan that starts from the fundamental physics of the space weather processes and designs, first, mathematical models best suited to accurately represent such processes, proceeds to develop computational algorithms target to the models at hand and finally implements a common integrated software infrastructure to make space weather forecasting possible. We organise our plan around a common multiphysics and multiscale work package, and 3 additional work packages designed to address the three main sources of linkages: the couplings at the Sun, in space and at the Earth. The main characteristic of our approach is to consider the physics first rather than the existing models. We will not piece together ill fitting existing pieces as one might be tempted to do. Instead, we will use the best knowledge available so far to design the best fitting model and software. We intend to take no shortcuts, we want to develop a sound and solid basis for space weather forecasting, to form the equivalent of what is now commonplace in regular meteorological models. The proposing team covers all aspects of the evolution of space weather events from the Sun to the effects on the Earth and includes experts with proven track record in the business of making space weather forecasts. We have extensive experience in the supercomputing facilities needed for space weather forecasting possible. We have experts on software development, on space weather modelling. and on the observations needed to help design the models and to test the results in a rigorous verification and validation approach. Our teams cover also geographically diverse areas of Europe and both founding and recent members of the EU.

Keywords: space weather modelling forecasting
Novel biomimetic strategy for bone regeneration (INNOVABONE)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: Austria,Germany,United Kingdom,United Kingdom,Switzerland,Spain,Spain,Germany,Italy,Netherlands,Germany,Belgium
Call:  (FP7-NMP-2010-LARGE-4, 2010)
Start date: 2011-11-01
End date: 2015-10-31
Duration (months): 48.0
Total project cost (EUR): 8015252.53
EU funding (EUR): 6199649.0
Participants: 14
Project status: CLOSED

The importance of developing novel approaches for bone repair is underscored by the heavy burden on health care costs and patient suffering caused by traumatic, osteoporotic and osteolytic metastatic bone lesions. To address these health challenges, we will develop optimally performing bioinspired biomaterials mimicking the natural physiological processes underlying bone repair. Our overall approach is to produce smart bioactive 3D scaffolds to fit within bone lesions, which we will then inject with functional, genetically-engineered self-solidifying elastin-like polymers with absolute-controlled molecular architecture and sequences containing specific domains for cell attachment, growth factors and calcium phosphate nanoparticles. The resulting bioactive, biodegradable scaffolds, biogels and regenerated bone will be analysed for biomaterial effects on bone growth, healing, foreign body reactions using cutting-edge in vitro assays, BioMEMS technology, in vivo animal models, non-invasive imaging and gene expression profiling for discovery of biomarkers associated with bone repair. Biomaterials will also be tested with biodynamic assays to assess strength, durability, toxicology, sterilisation reaction, eco-toxicology and risk assessment. Our multidisciplinary consortium with its extensive, state-of-the-art expertise consisting of private and public partners, cellular and molecular biologists, immunologists, physicists, bioengineers, and orthopaedic surgeons will tackle serious bone lesions with a comprehensive work plan to develop a prototype, evaluate it in vivo and in vitro, upscale its production and prepare the final material for clinical phase trials and commercialisation of the dual component product. Our ultimate aims are to ensure strong, healthy bone regeneration, reduce pain and suffering and to become a competitor in the biomaterials market of Europe.

Keywords: bioinspired scaffolds,hydrogels,osteoblasts,osteoclasts,bone biomaterials,osteoporosis
In-line characterisation of nanoparticles using a combination of analytical techniques in real time (IN-SIGHT)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Nanosciences and Nanotechnologies
Action type: Collaborative project
Countries involved: Netherlands,Germany,France,France,Belgium,Israel,Netherlands,Netherlands,United Kingdom
Call:  (FP7-NMP-2010-SME-4, 2010)
Start date: 2011-05-01
End date: 2014-04-30
Duration (months): 36.0
Total project cost (EUR): 4207239.0
EU funding (EUR): 3180000.0
Participants: 10
Project status: CLOSED

In-Sight is a SME-driven project on the in-line characterisation of nanoparticles during nanomaterial manufacturing. This in-line characterisation is the ultimate goal. Within the time-span of the project (3 years) it is our objective to show that a combination of analytical techniques that are capable of real time measurements will provide valuable information for the nanoparticle user. It is our objective to enable monitoring real-time (unexpected) changes in particle count and dimensions during particle processing. The outcome of the project will contribute to minimised batch failure, improved yield, troubleshooting scale-up. In addition, the in-line measurements will enable ‘quality by design’ throughout development of new products. Finally the result of the project will be reflected in a reduction of development time, as well as easy scale-up from the lab to manufacturing.

Keywords: in-line,real time,characterisation,nanoparticle,core-shell,ultrasonic,visualisation,raman-libs,nta,particle count,size-distribution,separation,automation