Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Photocaged Kinase Inhibitors as Molecular Tools for Investigating Neurodegenerative Diseases (PCAGED-KI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 173857.2
EU funding (EUR): 173857.2
Participants: 1
Project status: CLOSED

Protein kinases play a critical role in a number of cellular processes, including cell proliferation, differentiation and apoptosis. Recently, the aberrant regulation of lymphocyte-specific protein tyrosine kinases (LCK) has been associated with the over activation of microglia cells (important immune effector cells that reside in the central nervous system, CNS) and in turn, the development of Alzheimer’s disease (AD). Unfortunately, the detail of LCK's dynamic function and the importance of quantitative, spatial and time-dependent parameters regarding microglia activation is poorly understood. As such, the ability to manipulate LCK activity using light would result in temporal control of enzymatic activity, thus serving as a valuable approach to probe the function of LCK in microglia cells and in turn, further our understanding of AD and related neurodegenerative disorders. While such studies cannot be performed using conventional LCK inhibitors, this project aims to control the enzymatic activity of LCK by the development of a stimuli-responsive release-and-report system, through the introduction of a photolabile 'caging' moiety onto a fluorescent kinase inhibitor. The caging group will also consist of an appropriate ‘quencher’, quenching the innate fluorescence properties of the inhibitor through energy transfer (FRET). Exposure to light (> 320 nm) will result in decaging of the prodrug to give the active form, while simultaneously switching ‘on’ the fluorescence — reporting back to the user that the compound has been activated. To demonstrate the potential of the release-and-report kinase inhibitor as a tool to probe LCK function in microglia cells, confocal microscopy will be employed to visualise the site of microglia activation and the time frame during CNS development in zebrafish model systems.

Keywords: photocaging,spatio temporal control,fluorescence
Plasmon-resonance driven thermionic emitters for improved solar energy harvesting (PLASMIONICO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: CLOSED

PLASMIONICO is an innovative proposal aiming at advancing sustainable energy production by developing a "cold-cathode" thermionic generator as key component of novel photovoltaic/thermoelectric (PV/TE) hybrid devices to outperform the solar cell and thermoelectric generator working separately. The cold cathode, instead of being brought to extremely high temperatures, produces the emission of electrons by the absorption of infrared (IR) photons in the unused region of the solar spectrum below the PV cell bandgap. The IR photons will launch plasmons at a nanostructured metallic cathode, which upon relaxation will generate a photocurrent. A great advantage is that plasmon-resonance driven thermionic emission is not restricted to a particular class of materials, working for Si-based devices as well as for organic (soft and flexible) materials, since the cathode temperature is that of a working solar cell. Research activities will span the whole added-value chain from fundamental studies of materials for thermionic generation, including the optimization of plasmonic nanostructures, reaching higher TRLs by realization of a thermionic demonstrator. PLASMIONICO would contribute to the current energy challenge, a priority in both the EU and ICMAB-CSIC research agendas. The proposal possesses high interdisciplinary character by merging activities in physics, chemistry, materials science and device technology, which together with the unique network of international partners will contribute to boost the track records and develop the career of the applicant.

Keywords: solar energy conversion,thermionic emission,plasmon resonance,hot electrons,photovoltaic thermoelectric,hybrid device
Optimal System-Mix Of flexibility Solutions for European electricity (OSMOSE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: A single, smart European electricity grid
Action type: Innovation actions
Countries involved: Germany,Germany,Spain,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Spain,Spain,Spain,Italy,Italy,Spain,Italy,Spain,Italy,Switzerland,Serbia,Belgium,Slovenia,Slovenia,Switzerland,France,France,Portugal,Portugal
Call: Demonstration of system integration with smart transmission grid and storage technologies with increasing share of renewables (H2020-LCE-2017-SGS, 2017)
Start date: 2018-01-01
End date: 2022-04-30
Duration (months): 52.0
Total project cost (EUR): 27252680.56
EU funding (EUR): 21207868.71
Participants: 53
Project status: CLOSED

Six TSOs, eleven research partners, together with sixteen industry (manufacturers, solution providers) and market (producers, ESCo) players address, through a holistic approach, the identification and development of flexibilities required to enable the Energy Transition to high share of renewables. This approach captures synergies across needs and sources of flexibilities, such as multiple services from one source, or hybridizing sources, thus resulting in a cost-efficient power system. OSMOSE proposes four TSO-led demonstrations (RTE, REE, TERNA and ELES) aiming at increasing the techno-economic potential of a wide range of flexibility solutions and covering several applications, i.e.: synchronisation of large power systems by multiservice hybrid storage; multiple services provided by the coordinated control of different storage and FACTS devices; multiple services provided by grid devices, large demand-response and RES generation coordinated in a smart management system; cross-border sharing of flexibility sources through a near real-time cross-border energy market. The demonstrations are coordinated with and supported by simulation-based studies which aim (i) to forecast the economically optimal mix of flexibility solutions in long-term energy scenarios (2030 and 2050) and (ii) to build recommendations for improvements of the existing market mechanisms and regulatory frameworks, thus enabling the reliable and sustainable development of flexibility assets by market players in coordination with regulated players. Interoperability and improved TSO/DSO interactions are addressed so as to ease the scaling up and replication of the flexibility solutions. A database is built for the sharing of real-life techno-economic performances of electrochemical storage devices. Activities are planned to prepare a strategy for the exploitation and dissemination of the project’s results, with specific messages for each category of stakeholders of the electricity system.

Keywords: energy transition,integration of flexibility,market design
The efficiency of bio-self-healing concrete within ground conditions (GEOBACTICON)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-11-01
End date: 2020-12-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Concrete is the most used construction material worldwide for infrastructure projects. Due to deterioration, regular maintenance works are necessary to seal the concrete cracks and restore durability. In Europe, infrastructures such as tunnels and earth retaining walls alone cost approximately 5 billion EUR per year. Self-healing strategies (particularly bacterial-based self-healing) are regarded as a promising solution to reduce the high maintenance and repair cost of concrete infrastructures. It is believed if self-healing concrete had been used for all these structures, up to 120 million EUR could be saved annually on their maintenance. The research to date has tended to focus on the self-healing process in air or water environment. However, infrastructures (i.e. bridges, buildings, tunnels) are built on or in the ground, where part of their concrete structures are inevitably embedded in soil environment with all sorts of ground conditions such as different types of soil, saturation regimes, and chemical exposures. It is not clear if the process of self-healing is efficient within concrete elements exposed to such complicated ground conditions. The project aims to explore the efficiency of the bacterial-based self-healing (bio-hydrogels) in underground concrete structures. By using a novel interdisciplinary approach, the research combines state-of-the-art technologies applied in materials/concrete, geotechnical engineering, and microbiology to conduct a series of lab-scale experiments on mortar specimens incubated within various soil environments. Purpose-built experimental tools are used to investigate the effect of several factors including the type of soil, saturation regime and class of (chemical) exposures, on the bio-self-healing process. The outcomes of this research are highly relevant to the construction industry and the knowledge produced by the project will have an economic, financial and societal impact in EU and other regions.

Keywords: bio self healing concrete,soil mechanics,infrastructure engineering,mechanical testing,optical measurements
Water Recovery from Industrial Gas Streams at Moderate Temperatures (RECOVERY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

The emission of greenhouse gases is gradually changing the climate and the temperature of the Earth. As a consequence, droughts are increasingly occurring and freshwater is becoming a scarce natural resource. Water scarcity is actually a major issue in the south of the European Union (EU) territory. Since industry is one of the main water users in Europe, the purpose of this Fellowship is to recover water from industrial gas streams at moderate temperatures around 200–300 degrees Celsius using porous aluminium oxide membranes. Assuming that this challenging separation is successfully achieved, the project will have major impact on the industrial water footprint and management. In addition, this Fellowship also aims to give the Fellow, Dr Masó, the opportunity to develop new technical and transferable skills in the state-of-the-art membrane methodology and incorporate him into the EU academic/industrial membrane community.

Keywords: membranes,water recovery
SMEntorEGE (SMEntorEGE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Türkiye,Türkiye
Call: H2020 ENTREPRISE EUROPE NETWORK SGA4 2020-2021 (H2020-EEN-SGA4-2020-2021, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 149520.0
EU funding (EUR): 149520.0
Participants: 3
Project status: CLOSED

The general objective of SMEntorEGE is to support the regional SMEs to increase their efficiency and effectiveness in investments for research, development and innovation by improving their existing innovation capabilities, thus contributing to smart growth. The project SMEntorEGE aims to provide mentoring and coaching services to two different target groups of SMEs with the objective of increasing and accelerating the economic returns from innovation. The project has two main target groups: 1. SMEs with real potential for international growth via product/process/service/business model innovation but who lack the knowledge, skills or ability to manage innovation activities as a result of lack of offers and guidance. 2. SMEs who are the beneficiaries of “SME Instrument” (either in Phase I or Phase II of the project), Fast Track to Innovation (FTI) and Future and Emerging Technologies Open (FET-Open) but who need technical support and coaching in innovation management to enhance successful exploitation of the project and its contribution to the companies’ growth. As a result of the project, new types of standardised innovation support methodologies will be developed, the skills of the staff from the existing consortia will be improved, comprehensive innovation support will be given, EEN will be embedded in Regional Innovation Ecosystem, closer cooperation will be established between key innovation support providers and relevant stakeholders.

Keywords: innovation management capacity,smes,mentoring,coaching,key account management
Recovering carbon from contaminated matrices by exploiting the nitrogen and sulphur cycles (RECYCLES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Italy,Spain,Thailand,Canada,Chile
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2019, 2019)
Start date: 2020-01-01
End date: 2025-06-30
Duration (months): 66.0
Total project cost (EUR): 1209800.0
EU funding (EUR): 1209800.0
Participants: 8
Project status: SIGNED

The objective of the project is to exploit the integration of the carbon, nitrogen and suflur cycles in bioreactors to design optimal treatment trains to recover added-value products out of liquid and gaseous effluents. The strategy will be to combine interdisciplinary approaches to: - investigate innovative unit processes based on partial nitrification for nitrogen recycle, autotrophic denitrification for biosulfur recovery and multienzyme-based bioreactors for CO2 valorization; - apply technologies that are novel in this field such as moving bed bioreactors, membrane biofilm reactors and enzimatic reactors - combine biological processes in to innovative treatment trains for wastewater treatment and biogas upgrading. The topic will be addressed from the point of view of circular economy by exploring the potential synergies of carbon, nitrogen and sulfur cycles in wastewater and biogas treatment trains to reduce treament costs and to te increase production of added-value products. From a methodological point of view, the project targets the improvement of existing knowledge of innovative technologies based on immobilized biocatalysts as well as the demonstration of the viability of innovative treatment trains at in-silico, lab- and pilot-scale levels. The project is interdisciplinary and intersectorial; in fact, the research teams involved include environmental and chemical engineers, biologists and bioinformatics and mathematical modellers, while the companies are complementary being specialised in reactors design and construction and in bioprocess design and control. Finally, the involvement of the industry will allow to receive feedbacks on the solutions needed from pilot case studies using real effluents and to effectively translate novel scientific outcomes into suitable technologies.

Keywords: resource recovery,bioreactors,s cycles,integration,immobilized biocatalysts,bioprocesses engineering,wastewater treatment,waste gas treatment,innovative treatment trains
The Spanish permanent multilateral Smart Finance FORUM for Smart Buildings (AUNA)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Spain,Spain,Spain,Spain
Call: National roundtables to implement the Smart Finance for Smart Buildings initiative (H2020-LC-SC3-EE-2020-1, 2020)
Start date: 2020-10-01
End date: 2022-09-30
Duration (months): 24.0
Total project cost (EUR): 1030575.0
EU funding (EUR): 990200.0
Participants: 10
Project status: CLOSED

In extension of the work of the Sustainable Energy Investment Forums, AÚNA proposes to create in Spain a permanent, multilevel, multilateral discussion FORUM, fully focused on sustainable building financing, for the effective and wide implementation of the Smart Finance for Smart Buildings initiative, with the following differential characteristics: • From the building renovation sector, with a systemic approach led by Green Building Council España (GBCe) • Based on GBCe’s knowledge in the field, from the GTR Reports to the national and international coordination of stakeholders’ collaborative processes of H2020 BUILD UPON projects, and the launching in Spain of the green mortgages initiative EeMap, which put GBCe in a unique position • Able to bridge the gap between renovation and financing, by the incorporation at a leading discussion level of the most advanced players on all the interrelated aspects of financing, facilitated by the present openness of the financial world • Oriented to a shared understanding, to draw significant advances in terms of ideas, to be incorporated by the stakeholders to their practices and policies • Integrally based on the financial and stakeholders platforms aspects of the Commission Recommendation on Building Renovation • Totally aligned with the Spanish Long Term Renovation Strategy, of which it becomes a key stream in continuation of the work already started, with full support from the Interministerial LTRS group of Spain (ERESEE) • Four rounds of growing practical definition and outreach, with clearly defined progress indicators: a) preparatory; discussion FORUM definition and planning, b) extension to the wide renovation sector, c) citizenship outreach and d) shared contribution to the Spanish NECP and the ERESEE 2023 • Liaising with the SEIF organization and other relevant European Commission’s initiatives (e.g. Energy Efficiency Financial Institutions Group (EEFIG), Project Development Assistance (PDA) facilities, the Covenant of Mayors/SECAP initiatives”), international dimension through the European Network of GBCs, the Smart Cities and Communities (Lighthouse) network, and other consortium member networks

Keywords: financing,building renovation,energy efficiency,stakeholders community,discussion forums,best practices upscaling,dissemination,seif
Optimising hard carbon anodes for efficient energy storage in sodium-ion batteries (OptiCarb)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-11-01
End date: 2025-08-30
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

OptiCarb overall aim is to understand the fundamental mechanisms of sodium-ion intercalation/adsorption in hard carbon anodes and find the optimum carbon atomic configuration that maximises the sodium storage capacity. Experimentally it is difficult to unravel the mechanistic nature of sodium-carbon interactions, due to the complex atomic structure of hard carbons. Therefore, theoretical studies based on molecular simulations are crucial, as they can achieve atomistic resolution. However, up to date there is no realistic model capturing the microstructural complexity of hard carbons available in the literature, which hinders the subsequent study of the sodium-hard carbon interface. In this computational project I will use molecular dynamics simulations and an innovative methodology to generate realistic models of hard carbon anodes that capture porous and pseudo-graphitic domains into a single 3D-connected nanostructure. Our models will allow us to systematically study Na intercalation between pseudo-graphitic layers and Na adsorption in the confined space of carbon pores, which are key to optimise the Na storage capacity. To ensure maximum impact of the gained knowledge from our theoretical studies, I will closely work with experimentalists in my host group to validate and correlate our models with experimental data and guide the experimental design of optimised anodes with high Coulombic efficiency and high capacity. This will push the performance of Na-ion batteries to active long cycles (over 10000), high energy density (above 400 Wh/kg) and high Coulombic efficiency above 96%, making them competitive with commercial Li-ion batteries and paving the way for its large-scale commercialisation.

Keywords: carbon materials,non graphitising carbons,atomistic modelling,sodium ion batteries,ion intercalation,adsorption,energy storage,lammps