Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Design Challenge Pilot (DCP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Estonia,Greece,United Kingdom
Call: Peer learning of innovation agencies (H2020-INNOSUP-2018-2019-05, 2018)
Start date: 2019-09-01
End date: 2021-02-28
Duration (months): 18.0
Total project cost (EUR): 50000.0
EU funding (EUR): 50000.0
Participants: 3
Project status: CLOSED

The aim of the project is to enhance the co-creation philosophy to the service delivery system of urban challenge solving, through the inclusion of innovative SMEs in the design process. During the implementation of the project, the partners will peer review a co-creation procedure of setting up a solution that addresses a local challenge, satisfying the affected target group, capitalizing the expertise of the innovative SMEs of the region/country and enabling local authorities both improve the use of public money and raise their citizens’ satisfaction rates. The 3 partners, will peer-review other similar initiatives, in order to come up with a backbone of a “design service” offered to the local ecosystem by innovation agencies, that will enable cities, SMEs and citizens collaborate for the common good. The consortium members will set up a procedure where all the beforementioned parts will collaborate to “frame the challenge”, “ideate possible solutions”, “prototype” the best of them, “test” them in real life and adopt the ultimate one that satisfies the most, all stakeholders involved. In the end, the partners will set up a new service, which will be piloted in Greece by KEPA. The service will ensure that all stakeholders will be included and KEPA will facilitate the procedure of solving a social challenge by making maximum use of local SMEs expertise. The partners, based on the peer-learning activities and the Pilot Action, will develop a “Design Options Paper” –a guidebook on how other innovation support agencies can also cope with social problems and SMEs activation.

Keywords: innovation,smes,capacity,social challenges
Soluble IFNAR2 in Parkinson's disease and its role in the regulation of IFNβ in a neuroinflammatory context. (ParkIFNAR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-14
End date: 2022-09-13
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: CLOSED

Parkinsonian disorders (PDs) affect more than 1.2 million people in Europe with an estimated cost of €13.9 billion annually and have no cure. PDs have long been characterized by decreased motor activity, which is caused by the loss of dopaminergic neurons. Several disturbed processes have been described such as proteostasis, mitochondrial function and neuroinflammation, but its molecular mechanisms and their interactions are essentially unknown. There are recent evidences of alterations in the interferons’ (IFN) signalling involved in the neuroinflammatory processes of PDs. The host lab discovered the essential role of IFNβ signalling in the neuronal homeostasis of PD. The IFNβ receptor (IFNAR) plays a key role in the control of IFNβ cellular responses. However, the regulatory mechanisms, at level of its membrane subunits IFNAR 1 and 2, and especially its soluble receptor sIFNAR2 have not been characterized in PD-associated neuroinflammatory context. Most remarkably, the host lab has also identified a new mutation in IFNAR1 associated with a family of PD patients, and I have found that PDs present lower serum levels of sIFNAR2 than controls indicating dysregulation in this pathway. Based on our findings, I hypnotise that a defective IFNβ-IFNAR signalling is associated with PD pathology and this could be partly mediated by the function of sIFNAR2 as this protein is able to modulate the endogenous IFNβ and interplay with membrane-expressed IFNAR1 or IFNAR2. Fulfilling the tasks of this proposal will have strong potential to reveal the mode of action of sIFNAR2, as IFNβ-IFNAR signalling regulator, and as a novel molecule with intrinsic activities in maintaining & restoring the neuronal homeostasis and therefore could identify novel targets for treatment of PD. Through this MSCA-IF I would benefit from a unique training and expertise in one of the most cutting-edge laboratories of the research proposed here, and it will impact extremely my future scientific career.

Keywords: parkinson disease,ifn,soluble ifn receptor,neuronal homeostasis,ifn signaling regulation,neuroinflammation,pd mice model,neuronal and glia cultures,crispr,cas9,rna seq,chip seq
Water-based solutions for carbon storage, people and wilderness (WaterLANDS)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: Innovation actions
Countries involved: Austria,Germany,Estonia,Ireland,Italy,Ireland,Estonia,Estonia,Ireland,Spain,Belgium,Bulgaria,Bulgaria,Finland,Poland,Sweden,Finland,France,Netherlands,Netherlands,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: Restoring biodiversity and ecosystem services (H2020-LC-GD-2020-3, 2020)
Start date: 2021-12-01
End date: 2026-11-30
Duration (months): 60.0
Total project cost (EUR): 23631574.75
EU funding (EUR): 23068483.0
Participants: 34
Project status: SIGNED

WaterLANDS aims to enable an upscaling of the restoration of wetlands. Socio-economic factors, insufficient stakeholder engagement, lack of government commitment, lack of funding and inadequate exchange of knowledge of restoration methods have all been identified as barriers to successful restoration. Consequently, most restoration has been modest in scale, has occurred mainly where there is a single landowning or responsible organisation, and has often been undertaken principally for reasons of conservation. WaterLANDS will work to overcome these barriers. It includes both Action and Knowledge Sites, the former being the object of restoration upscaling, and the latter a source of best practice experience and knowledge. To provide for local support and sustainability, it will aim for the co-design of restoration with the on-going engagement of communities and stakeholders. It will investigate best practice in ecological restoration which meets both biodiversity and social objectives and for which restoration trajectories are specific to the physical and cultural context of the Action Sites. It will propose supportive governance structures appropriate to this process and to local and national circumstances. It will identify business models, economic incentives and international funding sources and tailor or direct these resources for each site. The project will pull this expertise and knowledge together in a co-creation work package. Process-indicators will be developed to enable on-going assessment of restoration success in terms of ecosystem services, socioeconomic embedding and financial sustainability, to ensure wide-scale restoration which catalyses scalability beyond the life of the WaterLANDS project.

Keywords: co creation,just transition,financial mechanisms,policy and governance
Integrated Tissue Slice Culture and NMR Metabolomics – A Novel Approach Towards Systemic Understanding of Liver Function And Disease (TISuMR)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Germany,Netherlands,United Kingdom
Call: FET-Open research and innovation actions (H2020-FETOPEN-1-2016-2017, 2016)
Start date: 2017-01-01
End date: 2021-12-31
Duration (months): 60.0
Total project cost (EUR): 3138432.5
EU funding (EUR): 3138432.5
Participants: 3
Project status: SIGNED

We propose the development of a groundbreaking technology platform that, for the first time, integrates nuclear magnetic resonance metabolomics and micro-imaging with microfluidic perfusion tissue slice culture. This will revolutionise life science research with unprecedented local insight into life processes in intact tissues under highly controlled conditions. We focus on liver tissue slice culture, with the immediate target of elucidating the mechanism of liver damage by drug-induced cholestasis. In the long term, the new technology will find wide application in other tissues, including intestinal, pancreatic, and brain slices. It will form the foundation of a new approach in the life sciences, allowing the detailed metabolic study of tissues at the system level. Liver disease is a significant and growing public health problem: 29 million people currently suffer from a serious liver condition in the EU. While the causes for some liver conditions are known, the mechanism of liver damage is generally poorly understood, largely due to the difficulty of studying live liver tissue at the systemic level. The proposed comprehensive research programme leads to a new technological platform for microfluidic tissue slice culture with direct observation of tissue metabolism and transport processes through nuclear magnetic resonance. It joins the expertise and creativity of four leading academic groups and one SME representing the disciplines of micro-engineering, physical chemistry, magnetic resonance, biochemistry, toxicology, and clinical hepatology across three institutions from three EU countries. Due to its high level of interdisciplinary integration, TISuMR is uniquely able to provide emerging researchers with a career springboard. TISuMR will have a profound impact on wider society by providing alternatives to animal testing, by increasing the efficiency and specificity of drug safety testing, and by enabling new treatments in the management of liver disease.

Keywords: nuclear magnetic resonance,tissue slice culture,liver pathology
Characterization and Measurement of Wideband Directional Channels in FM Band For New Efficient Wireless Systems (FM-4NXTG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Türkiye
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-05-01
End date: 2018-04-30
Duration (months): 24.0
Total project cost (EUR): 157845.6
EU funding (EUR): 157845.6
Participants: 2
Project status: CLOSED

Motivation: Wireless access is being used extensively in our life. Wireless access enabler, the frequency bands, on the other hand, is very scarce. It is very important that any wireless access system utilizes the frequency at outmost efficiency. One of the poorly utilized wireless bands is the FM Band between 88–108 MHz. The band is being allocated only for relatively high quality audio broadcast around the world. This band has good propagation characteristics and therefore its coverage range and its penetration through buildings are excellent. As FM coverage is so ubiquitous around the world, several applications are already considered to better exploit this useful band: (a) Software defined radios for public safety, (b) New digital audio broadcast services, and (c) the development of an emergency message delivery services. With one of these applications and good propagation characteristics, FM Band can enable a fully connected Europe. It is of significant interest to investigate and characterize channel properties of the FM Band for the potential wireless systems. Therefore, the objective of this novel research is for the first time to develop a complete channel characterization of FM Band and then to perform analytical directional channel modelling. The newly introduced models will then be validated through field trials, and will be able to support the parameters of the contemporary wireless systems with multiple antennae. Approach: The directional channel models will be developed through (i) geometrical (ray tracing) and (ii) tapped delay line (parametric stochastic modelling) approaches by considering 2-D (time and angular) channel impulse response. The models will be based on the specification of directional channel impulse response functions, large and small channel effects. The measurement campaigns will be carried out via channel sounders. Thus, we will have the first standard directional channel models of the FM Band.

Keywords: directional channel modelling,fm band,ray tracing,channel measurements
Carbon dioxide storage in nanomaterials based on ophiolitic rocks and utilization of the end-product carbonates in the building industry (CO2NOR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Cyprus
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2017-08-31
Duration (months): 24.0
Total project cost (EUR): 151648.8
EU funding (EUR): 151648.8
Participants: 1
Project status: CLOSED

Anthropogenic activities have increased atmospheric CO2 concentrations, which are considered to be the main cause of global warming. The EU has set itself targets for reducing its greenhouse gas emissions progressively up to 2050. A popular proposed solution to this crucial problem is carbon capture and storage (CCS). Ophiolitic rocks are considered among the most promising lithotypes for CO2 storage due to their high reactivity and many exposures in the world. In this proposal, an innovative and sustainable method for ex situ mineral carbonation will be suggested that will ensure the safe storage of CO2. This method includes the creation of novel nanomaterials via the ball milling process, based on low-cost ultramafic and mafic rocks from the Troodos ophiolite (Cyprus), which is considered as the most complete ophiolite worldwide. Although numerous studies have been carried out on the petrogenetic evolution of the Troodos ophiolite, a systematic work about the applicability of these rocks for CCS will be done for the first time in this study. Fines and waste material from quarries in the wider Troodos area will also be used for the development of nanomaterials. It is anticipated that ball milling will accelerate the kinetics of rock-fluid reactions during the carbonation procedure. Hence, carbonate minerals, which are stable over geological timescales, will provide a safe long term CCS solution. Additives will also be tested in the nanomaterials in an attempt to increase their CO2-storage capacity. The proposal also involves applied research in the form of exploitation of the end-product carbonates in the building industry. The successful outcome of this project will be based on the researcher’s extensive experience in the study of mafic and ultramafic ophiolitic rocks and mineral carbonation, as well as on supervisor’s expertise in the fields of nanomaterials and CCS.

Keywords: carbon capture and storage,ex situ mineral carbonation,ultramafic rocks,mafic rocks,nanomaterials,ball milling,building materials,troodos ophiolite complex,cyprus
Cultural Opposition: Understanding the Cultural Heritage of Dissent in the Former Socialist Countries (COURAGE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Research and Innovation actions
Countries involved: Ireland,Germany,Poland,Romania,Slovakia,Croatia,Hungary,Lithuania,Czechia,United Kingdom
Call: Cultural opposition in the former socialist countries (H2020-REFLECTIVE-SOCIETY-2015, 2015)
Start date: 2016-02-01
End date: 2019-01-31
Duration (months): 36.0
Total project cost (EUR): 2484917.5
EU funding (EUR): 2484917.5
Participants: 12
Project status: CLOSED

The project proposes both to create an electronic registry of representative online and offline, private and public collections of cultural opposition in all former socialist countries in Europe and to study the origins, uses and changing roles of these collections in their social, political and cultural contexts. We seek to further an understanding of how these (private and public, alternative and mainstream) collections work, what functions they serve in their respective societies, and how they represent their holdings to the public. The project will examine the legal and political circumstances that determined the collections before 1989 and the conditions that shape them in the post-socialist period. The analyses of the collections will identify various types of cultural opposition. Objectives include: 1. an online registry and a transnational database of collections in the original languages and English that will be accessible to European archival platforms and networks; 2. descriptions of and guides to the collections to enhance the quality of research and provide guidance on the role of the EU in this respect; 3. country reports on the collections and proposals concerning methods of preserving cultural heritage, and a handbook on various types of cultural opposition represented by the collections; 4. online curriculum development and digital content for educational purposes; 5. a documentary film festival, traveling and online exhibitions and local media events based on selected collections; 6. a set of recommendations concerning how to exhibit the cultural opposition movements of former socialist countries for the House of European History. This project will highlight the positive aspects of the former cultural opposition movements, such as democratic participation, autonomy and cultural plurality, and will remind us of an important pan-European truth: that civic courage can produce genuine cultural values even under authoritarian rule.

Keywords: cultural opposition,former socialist countries,european identity,register of collections,online database,fall of the socialist regimes,exile,histoire crois e,civil courage
Clean energy from ocean waves (CEFOW)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Innovation actions
Countries involved: Sweden,Finland,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Demonstration of renewable electricity and heating/cooling technologies (H2020-LCE-2014-2, 2014)
Start date: 2015-06-01
End date: 2020-05-31
Duration (months): 60.0
Total project cost (EUR): 24744113.75
EU funding (EUR): 16998022.13
Participants: 11
Project status: CLOSED

The most advanced wave power demonstrations today have showed the feasibility of power generation with single device deployments and MW-scale performance within several testing periods of several years. The next step beyond this is to deploy multiple wave energy converters in MW-scale with improved power generation capability and demonstrate that they are able to survive rough sea conditions over a period of several years. Clean Energy From Ocean Waves (CEFOW) project has an exceptionally good starting point. It has an existing site reservation in a wave power testing centre called Wave Hub, with all the needed infrastructure, including grid connection already in place. In addition, the wave energy converter technology to be deployed in the project has already been tested and proven in real conditions in Scotland. The ultimate purpose of the CEFOW is to increase the speed of wave power development, decrease the levelised cost of ocean energy by improving technical solutions used for multiple device system, and create an efficient supply chain to support larger wave power projects in the future. To reach these targets, the CEFOW consortium will improve the wave energy converter performance by 50% and raise its availability to 70%; develop new types of dynamic mooring and electrical connections suitable for multi-device deployment and deploy 3MW (three 1MW units) wave energy converters in real world offshore conditions in a grid-connected testing environment. In addition, CEFOW will study the feasibility of on-board and on-shore storage solutions and conduct thorough multi-year environmental, health and safety studies. The consortium spans the full value chain from research organisations to wave converter technology developers, marine service providers and a large multinational utility company as the operator.

Keywords: wave power,multiple device,real sea conditions,grid connected,full scale wec,wave hub,lcoe
Holistic Integration of Emerging Supercomputing Technologies (Hi-EST)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Spain
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-05-01
End date: 2020-04-30
Duration (months): 60.0
Total project cost (EUR): 1467783.0
EU funding (EUR): 1467783.0
Participants: 1
Project status: CLOSED

Hi-EST aims to address a new class of placement problem, a challenge for computational sciences that consists in mapping workloads on top of hardware resources with the goal to maximise the performance of workloads and the utilization of resources. The objective of the placement problem is to perform a more efficient management of the computing infrastructure by continuously adjusting the number and type of resources allocated to each workload. Placement, in this context, is well known for being NP-hard, and resembles the multi-dimensional knapsack problem. Heuristics have been used in the past for different domains, providing vertical solutions that cannot be generalised. When the workload mix is heterogeneous and the infrastructure hybrid, the problem becomes even more challenging. This is the problem that Hi-EST plans to address. The approach followed will build on top of four research pillars: supervised learning of the placement properties, placement algorithms for tasks, placement algorithms for data, and software defined environments for placement enforcement. Hi-EST plans to advance research frontiers in four different areas: 1) Adaptive Learning Algorithms: by proposing the first known use of Deep Learning techniques for guiding task and data placement decisions; 2) Task Placement: by proposing the first known algorithm to map heterogeneous sets of tasks on top of systems enabled with Active Storage capabilities, and by extending unifying performance models for heterogeneous workloads to cover and unprecedented number of workload types; 3) Data Placement: by proposing the first known algorithm used to map data on top of heterogeneous sets of key/value stores connected to Active Storage technologies; and 4) Software Defined Environments (SDE): by extending SDE description languages with a still inexistent vocabulary to describe Supercomputing workloads that will be leveraged to combine data and task placement into one single decision-making process.

Keywords: supercomputing,high performance computing,cloud computing,scientific computing,resource management,data centric computing,learning algorithms,deep learning,software defined environments