Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
BRaIn Disease monitoring throuGh the lifE span powered by Artificial Intelligence (BRIDGE-AI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Finland,Belgium,Netherlands,Germany,Austria,Switzerland,United States
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2025-11-01
End date: 2029-10-31
Duration (months): 48.0
Total project cost (EUR): 3997886.04
EU funding (EUR): 3626906.04
Participants: 18
Project status: SIGNED

BRIDGE-AI will train a new generation of innovative and entrepreneurial-oriented doctoral candidates (DCs) to move the state-of-the-art away from the snapshot interpretation of medical images by AI to a longitudinal follow-up and prediction of disease progression, covering a wide range of brain disorders across the entire lifespan. In an innovative departure of prevalent training models, each of BRIDGE-AI's DCs will be co-supervised by internationally leading experts from university research in biomedical image computing, world-renowned research hospitals, leading scanner manufacturers (Siemens, Philips) and medical imaging AI companies (incl. Bayer). Through this unique network, BRIDGE-AI will complete the entire circle from clinical needs to image acquisition, academic AI solution proposal, and commercial product for tracking disease progression and predicting treatment response in individual patients. Each of BRIDGE-AI's DCs will have a dedicated multidisciplinary and multisectoral thesis board, receiving input from industry, academia, and hospitals, and having access to large collections of clinical neuroimaging data, facilitating the evaluation of the true clinical relevance and impact of the proposed disease monitoring tools. Wide dissemination of the obtained methodological advances will be ensured by adopting a strong network-wide focus on open-source software.

Keywords: medical image computing,neuroimaging,brain diseases
Bimodal Ammonia Nuclear Thermal and Electric Rocket (BANTER)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Italy,Germany,Czechia,France
Call: EIC Pathfinder Open (HORIZON-EIC-2024-PATHFINDEROPEN-01, 2024)
Start date: 2025-02-01
End date: 2029-01-31
Duration (months): 48.0
Total project cost (EUR): 2997300.0
EU funding (EUR): 2997300.0
Participants: 4
Project status: SIGNED

BANTER represents the first step towards realizing an innovative bimodal nuclear thermal and electric propulsion system in which the same fluid (i.e. ammonia) is used as a propellant for thermo-nuclear propulsion and electric thrusters and as a working fluid for the power generation system. Due to its ease of storage in non-cryogenic conditions, its presence as an in-situ resource on many targets of future space missions, and its possibility of decomposing to increase the propulsive performance, ammonia allows the development of a compact propulsion system capable of transporting tons of payloads for a wide spectrum of missions. The design and verification through analysis of a nuclear reactor implementing a new type of coolant channels and a radiator-less power generation system fed by ammonia will constitute the first phase of this process. Then, the combination of the thermolysis, catalysis, and radiolysis processes to decompose the ammonia will be studied through two experimental campaigns carried out on prototypes of the coolant channels both in a nuclear and non-nuclear environment with the aim of demonstrating propulsive performance capable of outclassing traditional chemical propulsion systems. Moreover, another phase of design, development, and testing will demonstrate the ability of a cluster of newly designed ammonia electric thrusters to operate for long periods without excessive cathode erosion, eventually with increased efficiency due to the catalytic decomposition of the propellant. Positive outcomes of the project will pave the way for developing a technology that could make Europe a protagonist of the future space race thanks to a compact, versatile, and high-performance propulsion system. In addition, any improvement in the production of green hydrogen from ammonia decomposition will benefit also for the energy industry. This aspect makes this project highly multidisciplinary not only in the research approach but also in the results.

Keywords: nuclear thermal propulsion,nuclear electric propulsion,bimodal,catalysis,ammonia
Rural Sustainability Transitions through Integration of Knowledge for improved policy processes (RUSTIK)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Resilient, inclusive, healthy and green rural, coastal and urban communities
Action type: Research and Innovation actions
Countries involved: Germany,Austria,Spain,France,United Kingdom,Serbia,Poland,Belgium,Bulgaria,Italy,Slovenia,Finland
Call: Grasping rural diversity and strengthening evidence for tailored policies enhancing the contribution of rural communities to ecological, digital and social transitions (HORIZON-CL6-2021-COMMUNITIES-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 5886818.91
EU funding (EUR): 5838693.88
Participants: 32
Project status: SIGNED

The overarching objective of RUSTIK is to enable rural communities’ actors and policy makers to design better strategies, initiatives and policies fostering sustainability transitions of rural areas, through an advanced understanding of different rural functionalities, characteristics and future scenarios of rural areas, their potentials and challenges. Central specific objectives are to provide (1) a robust methodological framework for functional rural areas, (2) databases integrating data of different types and sources, (3), improved strategies and governance approaches for rural decision makers and stakeholders, and (4) improved approaches for rural impact assessment and decentralised rural proofing. RUSTIK aims to substantially contribute to enhancing existing European policy tools and approaches, most of all to support the European Green Deal, the European Digital Strategy, the European pillar of Social Rights and the EU Long-Term Vision for Rural Areas of the European Union. RUSTIK addresses the topic by illuminating three key transitions in rural areas, i.e. (1) socio-economic, (2) climate change and environmental, and (3) digital. Five types of rural functions are RUSTIK’s starting point for characterising the diversity of rural areas and their capacity to respond to these transitions. In order to achieve its overarching and specific objectives, RUSTIK will (1) create a conceptual basis for functional rural areas, transition and resilience of rural areas building on previous research, (2) co-design data collection approaches, and (3) investigate policy frameworks and coordination mechanisms. Closely interrelated with all of these activities, Living Labs in 14 European Pilot Regions in 10 European countries will be the central element of an action-oriented multi-actor approach to researching rural diversity and societal transformations.

Keywords: socio economic transition,climate change and environmental transition,digital transition,resilience,functional rural areas,rural proofing,living labs,co generation of knowledge,co design
CLINICAL VALIDATION OF MULTIMODAL BIOTHERAPY FOR GLIOBLASTOMA (Exo-3C)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Lithuania
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Glioblastoma multiforme (GBM) is the most aggressive central nervous system (CNS) tumour with no existing efficient treatment. Patients diagnosed with GBM generally succumb within 12-18 months after diagnosis. Therapies fail due to a lack of ability to deliver anticancer medicines through the blood-brain barrier and concentrate them in the GBM cells in sufficient amounts without causing damage to healthy tissues. Exolitus has developed stimulated immune cell-derived nanovesicles that can be loaded with several types of anticancer medicines, efficiently migrate from the periphery to the brain, selectively fuse with cancer cells and suppress their growth, migration, and tumour vascularisation. EIC funds will be used to perform phase I/II clinical validation studies, establish GMP production for clinical grade Exo- 3C, and secure regulatory approvals.

Keywords: glioblastoma multiforme,extracellular vesicles,macrophages,microglia,blood brain barrier,drug delivery,immunomodulation
Joint Cross-Border Polluted Site Decontamination PCP (joint POSIDON PCP)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EU prize
Destination: European Innovation Procurement Awards
Action type: Recognition Prize
Countries involved: Italy,Spain
Call: Innovation procurement initiative (including implementation) category (HORIZON-EIC-2024-PRIZE-EIPA, 2024)
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 6
Project status: CLOSED

The joint and cross-borderPOSIDON pre-commercial public procurement has been a pivotal force in transforming a highly fragmented and innovation-averse sector—environmental remediation of brownfields. Brownfields, sites with limited territorial availability, represent a growing challenge in Europe, where land has become a scarce and valuable resource. The need for sustainable development has intensified the urgency of recovering and reusing these contaminated areas. POSIDON's procurement strategy addresses this by aligning with sustainable growth goals, focusing on in-situ soil decontamination solutions for complex, highly polluted sites. POSIDON PCP is distinguished by its innovative procurement approach, driving the development of breakthrough solutions in areas where no commercially viable options previously existed. Five leading public procurer launched a competitive call for tender to address the decontamination of brownfields polluted by petroleum hydrocarbons and heavy metals. Two cutting-edge technologies—"Soil-Omic with BIOflushing " and "ERASE"—were selected for pilot testing based on their cost-effectiveness and potential to disrupt the market. These technologies represent a leap forward in environmental remediation, particularly for brownfield where traditional technologies have long application times and high costs. The in-situ approaches were tested in Italy and Spain, ensuring their readiness for large-scale application. This PCP initiative has not only fostered the development of these innovative technologies but has also prepared the ground for widespread adoption and market leadership in the European soil decontamination sector. By aggregating demand across borders and ensuring the harmonization of innovation goals, POSIDON exemplifies a transformative shift toward buying innovation process itself, marking a new era in brownfield remediation.

Keywords: in situ decontamination,cost effective innovation,brownfield remediation,technological transformation
Distributed Ledger Technology for Europe’s Digital Future (HashNET)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Croatia
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 48.0
Total project cost (EUR): 2.5
EU funding (EUR): 2.5
Participants: 1
Project status: SIGNED

Competitive DLT applications cannot provide the security, scaling, and performance needed for the EU government and business use cases. HashNET’s DLT infrastructure overperforms the competition by 10x-25x, making it suitable for the job. The global DLT market was valued at approximately USD 17.57 billion in 2023. It is projected to grow to USD 27.84 billion by 2024 and reach USD 152 billion by 2029, with a CAGR of about 45.2% from 2024 to 2029. HashNET aims to become the main DLT protocol for the European Blockchain Service Infrastructure. Our innovation is the HashNET Distributed Ledger Technology platform, which achieves up to 20,000 transactions per second using EVM smart contracts. After raising 25,000 ETH, SI-Chain, the world’s first national DLT infrastructure, was created with Slovenia's government. Collaborating with the EU, we aim to be at the forefront of the EU DLT ecosystem, offering fast, energy-efficient, and secure infrastructure for users from the government, military, and business. Selection of HashNET EU Projects (Total Value: €3 Billion) IPCEI CIS Dome EBSI Vector Trace4EU EBSI NE EDIH HashNETs participation in the IPCEI CIS project under SAP and Engineering proves our technological capabilities and strategic alignment with EU objectives. This involvement enhances our proposal to the EIC by demonstrating our role in a significant EU-backed initiative and underscores our potential to drive substantial economic, technological, and societal benefits. The success of this project could establish HashNET as a leader in the European DLT space. By supporting HashNET, the EIC and other investors could contribute to a technology that promises to revolutionize data sharing and operational efficiency across various sectors, fostering innovation, security, and economic growth in Europe and beyond.

Keywords: empowering europe s digital transformation
Geometric approach to many-body quantum chaos (GeoChaos)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 1999988.0
EU funding (EUR): 1999988.0
Participants: 1
Project status: SIGNED

Quantum chaotic dynamics is in the focus of many current developments in physics, ranging from thermalisation in closed quantum systems to the black hole information puzzle. Recently, experimentalists have made great strides in controlling quantum dynamics, and theorists have developed solvable models to study many-body quantum chaos. To uncover what aspects of these results are universal and how different chaotic phenomena across time scales are related, a coherent framework unifying and extending recent developments is called for. This project will develop two new paradigms that unify different manifestations of quantum chaotic dynamics and bridge disciplines. In the quest for a common dynamical explanation of different chaotic phenomena, we will construct a Unified effective field theory (EFT) for chaos. In parallel, we will capitalise on the holographic Gauge/String duality that gives geometric insights into strongly coupled quantum dynamics to draw connections between gravity and chaos. By developing a holographic dictionary between the Unified EFT and gravity, we will build the Chaos/Gravity correspondence, a novel framework that uncovers how spacetime and its gravitational dynamics emerges from chaos in quantum field theories. Our methodology consists of exact analytical computations in solvable models, the study of chaotic phenomena in universal kinematic regimes, and the description of these results in the framework of EFT. These steps lay the foundations for conceptual leaps to the Unified EFT and the Chaos/Gravity correspondence that will be pursued in synergy. The two new paradigms will transform our understanding of many-body quantum chaos. The benefits of a systematic approach will be multifold: we will establish new quantitative relations between data characterising chaos, make experimental predictions about non-equilibrium phenomena at large system sizes, and potentially uncover new signatures of quantum chaos.

Keywords: many body quantum chaos,effective field theory,holographic duality,ads cft,out of time order correlators,entanglement entropy,complexity,syk model,black holes,random quantum circuits,finite temperature qft,random matrix theory
A Land of Joiners. A Gender History of Volunteer Fire Departments in a Three-Border-Region of East Central Europe in Times of Political Transformation, 1918-1989 (A Land of Joiners)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-03-01
End date: 2025-02-28
Duration (months): 24.0
Total project cost (EUR): 190728.96
EU funding (EUR): 190728.96
Participants: 1
Project status: CLOSED

This project looks at East Central European (ECE) history by focusing on non-state actors and particularly on voluntary associations. Challenging the received view that Western Europe (WE) and the Atlantic World are the authentic cradle of associations and of an appropriate and healthy civil society, e.g. the USA often epitomised as the “nation of joiners”, this project interprets voluntary associations in ECE as variation of and not deviation from a unique-but-universalized WE and Atlantic model. New studies on associational life in ECE suggest that well-established theoretical dichotomies like state/non-state, governmental/civil, public/private need to be overcome and argue that voluntary associations always actively interacted with the political context and contributed to shaping it (Giomi/Petrungaro 2019). This research seeks to revisit these theses by focusing on a particular voluntary association, Voluntary Fire Departments (VFD), which in ECE exists almost uninterruptedly since the mid-19th century under democratic, authoritarian or dictatorial regimes alike. Focusing on social history from below and transnational connections, this research will interrogate the question in what way did political ruptures from the end of the First World War until the end of the Cold War in ECE alter membership structure and gender policies of VFDs as well as how did VFDs interact and react with the political ruptures in regard to social inclusion and exclusion along the lines of gender? The project covers the territories of today's Austria, Hungary, and Slovenia, but more specifically three regions: Burgenland, Vas, and Prekmurje, where the concentration of VFD is the largest worldwide. By seeking to counter the marginalisation of volunteering within the social histories of ECE, and of ECE within the global histories of voluntary associations, the project contributes to the current debates about gender equality and equal participation in the European Union.

Keywords: voluntary associations,east central europe,contemporary,social and gender history,democratisation,border region,volunteer firefighters
Enantioselective N-α C(sp3)-H Functionalization of Amides by Trifunctional Catalytic Systems (ENCHFATCS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: CLOSED

The trifunctional catalytic systems (TCS) consisting of bifunctional photocatalysts and transition metals will be designed to achieve the enantioselective N-α C(sp3)-H functionalization of amides (ENCHFA). Mechanistically, the bifunctional chiral hydrogen bonding-based aryl ketones will activate the amides to form α-amido radicals via HAT and control their reactivity in an enantioselective manner while transition metal will provide another opportunity to active substrates and accomplish the photocatalytic cycle via a radical relay. Combining chiral hydrogen bonding-based aryl ketones with Co catalysis, the protocol will develop the external oxidant-free enantioselective N-α C-H alkenylation, arylation and alkoxylation of amides with H2 evolution. Furthermore, the enantioselective N-α C-H trifluoromethylation of amides will be relized by merging chiral hydrogen bonding-based aryl ketones with Cu catalysis. The trifunctional catalytic systems will not only enrich the types of enantioselective C-H functionalization of amides, but also reveal the mechanism of trifunctional catalytic systems, as well as provide guidance for designing multiple systems in asymmetric catalysis.

Keywords: photocatalysis,enantioselectivity,radicals,hydrogen atom transfer,transition metal catalysis
Enhancing Magnetic Permeability of Concrete to Boost Efficiency of Wireless Power Transfer (WPT) on Electric Roadways (HMPC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-05
End date: 2028-01-04
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 2
Project status: SIGNED

The transition from fossil-fuelled vehicles to electric vehicles (EV) plays a vital role in efforts to reduce greenhouse gas emissions and ultimately achieve net zero by 2050. However, the main challenges currently facing EV revolve around battery technology, availability of charging infrastructure and limited driving range. To tackle these challenges, the implementation of dynamic wireless charging (DWC) systems for EV is a key strategy on the agenda in the world. This project aims to develop a high magnetic permeability (MP) and cost-effective concrete (HMPC) for use in road pavement over static/dynamic wireless energy transfer (WPT) charging pads to enhance WPT efficiency. The project will explore two different techniques, maximising the success rate of achieving the main project goal. It will focus on developing high MP aligned steel fibre reinforced concrete panels to be bonded to charging pads or road surfaces as well as the development of high MP magnetite aggregate concrete panels. It is expected that the project outcome will improve WPT efficiency by reducing energy losses in existing electric roads between 0.5% and 3%. In addition, economic, disseminable and sustainable concretes will be developed by using low cost, high availability and sustainable materials instead of extremely expensive metals, such as cobalt and nickel. The researcher will receive comprehensive training to enhance his future career, gaining expertise in new analytical and experimental techniques, project management, advanced training methodologies, supervision, academic publishing, patent writing, and preparing funding proposals. Furthermore, the project will ultimately contribute to the sustainability of energy resources, the reduction of greenhouse gas emissions and create new job opportunities.

Keywords: high magnetic permeability concrete,magnetisable concrete,wireless power transmission efficiency,inductive energy transfer,aligned steel fiber,magnetite aggregate,concrete panel,electric road