Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Making Green Audiovisuals sustainable (GreenVisuals)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Belgium
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-06-01
End date: 2023-11-30
Duration (months): 6.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Audiovisuals create impactful communication. Viewers retain 95% of a video message versus 10% for text. Brands that use video marketing experience revenues that grow 49% faster. Even this submission includes a video. GreenVisuals supports TheGreenShot’s entry in the market of producing sustainable commercials– starting from its current offering for films and TV series. I am Véronique Pevtschin, CEO of TheGreenShot – part of a gender-balanced founding team - 2 women, 2 men. TheGreenShot has brought to market the 1st solution that accelerates the move to sustainable productions for films and TV series. Developed over 3 years, How did we achieve that? By thinking differently. 1) Today, carbon footprints are generated by accounting teams that start from financials. They compute footprints from how much work costs. We compute footprints starting from how work is done. 2) Accounting teams compute carbon footprints after the facts. We compute carbon footprints in real-time. 3) We also share granular carbon footprints in real-time with people on the field. Numbers relevant to individuals and teams, empowering them to act. 4) We propose alternative solutions and providers directly inside our app. Our automations remove the additional costs of computing footprints and generate custom reports that facilitate certifications and ESG reporting. In 15 months, TheGreenShot has gained market traction with 10 clients in Europe, US and Canada and professional recognition through 5 awards. Its team has grown from 4 to 18 people. We have the innovative solution, the team and the ambition – this grant is ideally positioned in content and timing to help us enter a new, yet accessible, market. Structured around two phases - creating the right business channels and preparing the optimal content for our next investment round - GreenVisuals helps TheGreenShot reach its next growth milestone.

Keywords: sustainability commercials esg
Multi-sensor Eversion Robot Towards Intelligent Endoscopic Diagnosis and Therapy (EndoTheranostics)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Italy,United Kingdom
Call: ERC Synergy Grants (ERC-2023-SyG, 2023)
Start date: 2024-07-01
End date: 2030-06-30
Duration (months): 72.0
Total project cost (EUR): 7616426.25
EU funding (EUR): 7616426.25
Participants: 4
Project status: SIGNED

Colorectal cancer (CRC) represents a significant proportion of malignant diseases. Interventions are often carried out during the latter stages of development, leading to low patient survival rates and poor quality of life. In 2022 a European Commission report stated that “colonoscopy-based screening has higher sensitivity than testing for blood in stool, but it is less acceptable to participants”. At the same time, effective methods to treat polyps in the colon are limited. Current approaches are often associated with unsafe oncological margins and high complication rates, requiring life-changing surgery. EndoTheranostics will usher in a new era for screening colonoscopy, advancing the frontiers of medical imaging and robotics. A tip-growing or eversion robot with a sleeve-like structure will be created to extend deep into hollow spaces while perceiving the environment through multimodal imaging and sensing. It will also act as a conduit to transfer miniaturised instruments to the remote site within the colon for diagnosis and therapy (theranostics). With these capabilities, the system will be able to offer: 1. painless colon cleansing in preparation for endoscopy; 2. real-time polyp detection and tissue characterisation through AI-assisted multimodal imaging; 3. effective removal of polyps by conveying a “miniature mobile operating chamber” equipped with microsurgical tools to the target through the lumen of the eversion robot. The unique technical and clinical challenges will be tackled by the PIs, each bringing complementary skills, backed by their institutions with wide expertise and exceptional facilities. The synergy and added value evident in this team will lead to breakthroughs not possible through independent research. The outcomes of EndoTheranostics will revolutionise the theranostics of CRC, impacting the quality of life of millions of individuals. Ultimately it will launch a new era for endoluminal intervention with applications beyond medicine.

Keywords: soft robotics,inflatable robots,medical imaging and perception,tissue characterisation and registration,microsurgery,natural orifices translumenal endoscopic surgery notes,autonomous control and manipulation,intervention shared control
MediaCare: Empowering Caregivers of Children with Neurodevelopmental Disorders through Media Literacy. (MediaCare)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Netherlands,Sweden
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 3
Project status: SIGNED

In our digitally driven world, caregivers of children with Neurodevelopmental Disorders (NDDs) deal with an avalanche of information. While information is more accessible than ever, it is also more prone to misinformation, adding to the already significant challenges these caregivers face. The EU defines misinformation as misleading or false information spread across various media. Such misinformation, often disguised as genuine advice, can mislead caregivers, affecting their care decisions and steering them away from evidence-based approaches. In its commitment to fostering a digitally inclusive society and fight misinformation, the EU agenda highlights the role of media literacy, enabling individuals to evaluate and critically interpret media messages. Yet, a gap exists: no media literacy initiatives are tailored to the unique needs of caregivers of children with NDDs. MediaCare is an interdisciplinary initiative blending media literacy and care research to bridge this gap. In MediaCare, I aspire to develop a novel web-based application to enhance media literacy skills for caregivers of children with NDDs. MediaCare objectives are clear: (1) To identify prevalent caregiver media misinformation on NDDs; and to build the MediaCare app to counteract them, offering (2) trusted resources, (3) aid in discerning information, and (4) fostering a digital care community. With a User-Centered approach and gold-standard methods, from a stakeholder-engaged review to usability testing and a Randomized Controlled Trial, MediaCare aligns with the EU's Digital Education Action Plan, promising a pioneering media literacy solution for caregivers. The FORLIPSI department at the University of Florence, a leader in media literacy research, offers me an ideal setting for this project, under Prof. Christian Tarchi’s guidance. MediaCare is expected to empower caregivers, enhancing their ability to navigate the media realm confidently and promoting informed, evidence-based care decisions.

Keywords: caregivers caregivers of children with neurodevelopmental disorders parents misinformation media literacy
Fifth Generation Services HUB for European Union Governmental Satellite Communications (5G-HUB)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: EU Space
Destination: EU Space
Action type: Innovation actions
Countries involved: Italy,Spain,Portugal
Call: EU GOVSATCOM for a safer and more secure EU (HORIZON-EUSPA-2023-SPACE, 2023)
Start date: 2024-11-01
End date: 2027-10-31
Duration (months): 36.0
Total project cost (EUR): 3633533.75
EU funding (EUR): 2895108.88
Participants: 10
Project status: SIGNED

Satellite communication networks in Europe have been in the market for more than 40 years with consolidated capacity to connect remote areas and represent an essential tool for state members. Therefore, it is evident that there is a need to allow the satellite operators to manage GOVSATCOM users efficiently with the overall available resources. This project aims to evolve the flagship European initiative “GOVSATCOM-HUB” to improve the flexibility of satellite network operators in allocating their resources to the needs of GOVSATCOM users. This goal will require the development of a new interface between the G-HUB and the 5G core network entities and microservice-based services interacting among them to provide network management tasks. Moreover, the 5G-HUB project will address the interoperability issues, allowing the GOVSATCOM user terminal to connect to different space assets, eventually including terrestrial systems. This project aims to validate the G-HUB functions in three trials with the initial development of a unified 5G NTN terminal in Ku and X bands. The trials will aim to verify the system performance in terms of resource allocation, quality of service provision, and capacity to switch communication (traffic steering) from the satellite network to the terrestrial network in a way that is unnoticeable to the user. These trials will be based on critical scenarios of emergency management where there is the need to coordinate teams in remote areas where satellite systems mainly provide connectivity. The interoperability of different satellite operators will also be investigated in this context.

Keywords: disaster resilience and crisis management,unified terminals
PERSONALIZED NON-INVASIVE NEUROMODULATION IN PAIN (PersoNINpain)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Denmark
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-08-01
End date: 2028-07-31
Duration (months): 60.0
Total project cost (EUR): 1618278.0
EU funding (EUR): 1618278.0
Participants: 1
Project status: SIGNED

Chronic pain (CP) is the most prevalent disease worldwide and is a major societal challenge. Different people with the same pain condition experience it differently. Irrespective of its origin, CP is maintained by altered connectivity between brain regions, which can be modulated towards normality by effective treatment. Several pharmacological and non-pharmacological strategies exist to treat pain, but 40% of individuals remain symptomatic despite treatment. Current treatment for CP is not personalised, being delivered in a standardised regimen irrespective of patients' brain network status, which partially justifies therapeutic refractoriness. Non-invasive neuromodulation (NIN) techniques such as repetitive transcranial magnetic stimulation (rTMS) are used in the long-term treatment of a wide spectrum of brain disorders as an alternative to medication-exclusive regimens. NIN can modulate altered connectivity towards normal patterns and relieve symptoms with minimal side effects, but to date its application has also been non-individualized, which equally impacts its therapeutic potential. I propose a comprehensive package of studies using measurements of local-to-global brain connectivity to individualize pain treatment. By probing different brain regions by single pulse-TMS and reading the subsequent brain oscillatory responses by electroencephalography, one can screen potential treatment targets and classify them according to their efficacy potential in a pre-treatment session. This will allow the identification of the best cortical region to be used as treatment target by rTMS, thus providing a personalized choice of the ideal entry-spot to drive brain global connectivity towards normalized patterns for each patient. With the development local-to-general brain connectivity metrics guiding NIN treatment, PersoNINpain will provide an innovative and ground-breaking approach to transform the treatment the world’s most impactful health condition - chronic pain.

Keywords: chronic pain,neuropathic pain,neuromodulation,neuropathic pain,parkinson disease
Discerning the mEchanisms of stem cell protection against COgnitive DEcline in paediatric brain tumours (DECODE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 194074.56
EU funding (EUR): 194074.56
Participants: 1
Project status: SIGNED

The primary objective of this MSCA-PF proposal is to support Dr. Laura Pérez Alós in becoming an independent investigator by conducting the innovative DECODE project. DECODE aims to explore the role of the complement system in modulating the neuroprotective mechanism of mesenchymal stem cells (MSCs) in radiotherapy-induced brain inflammation (RIBI) in paediatric brain tumours. Specifically, the project will investigate the role of complement in RIBI using juvenile mice of both sexes, and the interaction between the complement system and MSCs will be assessed through in vitro cell culture models and in vivo juvenile mouse models of brain irradiation. Additionally, the project will evaluate the synergistic effects of complement modulators in combination with MSCs to mitigate the neurocognitive dysfunction caused by RIBI. The research will be supervised by Dr. Vivian Capilla González, leader of the Stem Cells and Translational Neurology group at the Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), a cutting-edge research centre that fosters excellence in scientific discovery in Spain. Dr. Pérez Alós, an expert in pharmacy and immunology, deeply focused on the complement system, will collaborate with Dr. Capilla González, who brings extensive expertise in brain irradiation mouse models and MSC modulation. DECODE ensures a multidisciplinary research approach, providing Dr. Pérez Alós with comprehensive training to facilitate her growth as a leader and independent researcher. The project’s findings are expected to pave the way for future collaborations and drive the development of MSC-based therapies for RIBI towards clinical application, ultimately offering safer and more effective treatment options for paediatric cancer survivors. The success of DECODE will create new opportunities for Dr. Pérez Alós to secure her long-term career as an independent investigator.

Keywords: mesenchymal stem cells,radiation induced neuroinflammation,neurocognitive dysfunction,paediatric brain tumour,complement system
Inertial Dense Suspensions (IDeS); Flows in between Laminar and Turbulent (IDeS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Netherlands
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2025-12-01
End date: 2030-11-30
Duration (months): 60.0
Total project cost (EUR): 2463893.0
EU funding (EUR): 2463893.0
Participants: 1
Project status: SIGNED

Inertial Dense Suspensions are very common in nature and industry, with examples including blood flow, recycling, waste slurry transport, additive manufacturing, and energy storage solutions. While they are of great practical importance, these suspension flows are poorly understood. A direct consequence is that we cannot predict even the most basic properties of these flows with sufficient accuracy. For instance, the current best models over- or underestimate the measured pressure drop in a suspension pipe flow by 30-40% for various flow rates. This means that designing or controlling these flows is difficult, as there is no reliable relation between the flow rate and pressure difference (i.e. pumping power) for a given suspension. Our inability to predict these flows stems in part from the fact that they defy the conventional dichotomy of ‘laminar’ versus ‘turbulent’ flow; they inhabit a terra incognita. Most theoretical studies so far have been limited to confined suspensions in the viscous regime. In the applications mentioned, this idealized approach is not valid: Due to the finite size and velocity of the suspended particles, several inertial phenomena occur, such as particle-induced fluctuations, a gradual transition to turbulence, and shear-induced migration. These are at best only qualitatively understood, yet they dramatically alter the flow behavior. We can only now start investigating these flows systematically. The opacity of suspensions severely limited our ability to obtain experimental data using conventional flow measurement techniques. In recent years, I pushed the capabilities of non-optical techniques (e.g. ultrasound, MRI), which have opened up this important field. Using unique experimental facilities supplemented with resolved simulations, I will obtain the much-needed data and study the fundamental physics involved in this problem. I will use this to construct a comprehensive conceptual model and then reduce it to formulate predictive rules.

Keywords: experimental fluid mechanics,multiphase flow
Measuring the shape of the electron with ultra-cold molecules (eShapeUltracold)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

One of the most puzzling observations in contemporary physics is the striking imbalance of matter over antimatter in our Universe. The Standard Model of Particle Physics predicts that nearly equal amounts of matter and antimatter should have been created, but all the antimatter seems to have disappeared. This discrepancy could be explained by a new particle or interaction that breaks the symmetry between matter and antimatter. Many different experiments are looking for signatures of this broken symmetry (CP violation) using a wide variety of particles, atoms and molecules. The CP-violating signature this project focuses on is an asymmetry in the shape of the electron, quantified by its electric dipole moment (EDM). The aim is to measure the EDM of the electron with tenfold better precision compared to the current state-of-the-art experiments. Such an unprecedented sensitivity can be achieved by using ultra-cold molecules instead of cold molecules, their slower speeds increasing the time spent in the sensitive region of experimental apparatus. However, the longer interrogation times bring new challenges regarding experimental stability and systematic effects. The objectives of this project are to use my expertise in magnetic field optimisation and high-precision experiments to tackle these challenges and to collect and carefully analyse the electron EDM data, testing predictions of new physics. This fellowship would give me the opportunity to learn how to create, control and detect ultra-cold molecules from the world-leading experts at Imperial College, and the curated training programme will allow me to grow into an independent researcher capable of leading my own research group. These skills are crucial in the next stage of my career as I want to continue with these tabletop experiments with molecules for fundamental physics, probing for new physics beyond the energy range accessible by the accelerator-based experiments such as at the LHC.

Keywords: electric dipole moment,fundamental symmetries,cp violation,magnetic field stability,high precision experiment
Metabolic flexibility in drought: Leveraging Portulaca for defining design principles for a combined C4-CAM pathway (METACAM)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Biotechnology and Biosystems E ngineering
Panel description: Biotechnology using all organisms , biotechnology for environment  and food applications, applied plant and animal sciences , bioengineering and synthetic biology , biomass and biofuels , biohazards
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Rising heatwaves and drought are severely affecting the capacity of crops to retain water and capture CO2 during photosynthesis, resulting in global yield reductions. One of the most promising approaches to enhance crop production in stressful conditions is to synthetically modify the photosynthetic capacity of plants. In nature, some lineages have evolved mechanisms like C4 photosynthesis and the Crassulacean acid metabolism (CAM) to cope with some of these aspects; While C4 species are extremely efficient at CO2 fixation but vulnerable to severe drought, CAM plants are less productive but very capable of coping with significant drought periods. Engineering a joint C4-CAM system that uses CAM features to fight drought, while still relying on the power of C4 can be a game-changer to increase crop resilience. For decades, the coexistence of C4 and CAM was considered incompatible in nature. An exception to the rule is found in the genus Portulaca where C4 species can trigger CAM when droughted. Despite the huge bioengineering potential of Portulaca, the molecular enablers that allow for C4-CAM to exist in this clade remain elusive. Previous phylogenetic and morphological studies across Portulaca indicate the combined C4 (Kranz anatomy) and CAM (succulence) leaf anatomy might be the main facilitator of C4-CAM. By combining anatomical studies, cell specific metabolomics and genomics with synthetic biology, I aim to identify the basic molecular determinants of the C4-CAM switch in Portulaca, and to leverage this knowledge to transfer CAM anatomical features to C4 species outside Portulaca as a proof of principle. This will set the basis for new rounds of engineering to achieve a fully functional C4-CAM switch. METACAM will provide a quantum leap to our understanding on how incompatible metabolic pathways can be designed, built and integrated in multicellular organisms which is broadly applicable to crop engineering.