Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Microelements in Life Expectancy and Aging (MILEAGE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Ukraine,Cuba,Jamaica,France,France,United Kingdom,Chile
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2016, 2016)
Start date: 2017-05-01
End date: 2023-08-31
Duration (months): 76.0
Total project cost (EUR): 864000.0
EU funding (EUR): 864000.0
Participants: 7
Project status: SIGNED

Increased longevity with a high quality of life is desirable not only for personal life-satisfaction but also for reducing healthcare costs and for increasing the socioeconomic contributions of individuals in countries with ageing population demographics. Lifelong lifestyle has an important impact on health status in older age and adequate nutrition plays a key role in maintaining cellular functions within normal limits. Microelements such as zinc (Zn) and copper (Cu) are essential for life and are involved in the normal functioning of thousands of proteins. The dysregulation of these metals leads to perturbed homeostasis, disease and diminished quality of life. In this study, the molecular mechanisms by which ageing affects Zn and Cu absorption and excretion will be determined, and the consequent impact on metal flux and transport kinetics will be expressed by mathematical modelling. The project output will include a predictive model for the impact of ageing on Zn and Cu homeostasis, informing intervention with dietary advice or supplementation to improve longevity. The consortium combines intersectoral and interdisciplinary expertise from 3 EU and 2 partner countries with established links and clear potential for knowledge exchange and transfer of skills. The consortium objectives are: 1. To determine the impact of dietary Zn and Cu on the microbiota and also age-related changes in the microbiota composition on the absorption of Zn and Cu. 2. To understand the influence of senescence on the regulation of Zn and Cu flux into and out of key cells controlling their homeostasis (gut mucosal cells, pancreatic acinar cells and hepatocytes) and its impact on the expression of related genes such as transporters. 3. To determine how senescence affects the transporter proteins, channels and chaperones involved in regulating Zn and Cu trafficking through the key absorptive and excretory cells affecting body metal homeostasis.

Keywords: zinc,copper,nutrition,transporters,ion channels,kinetics,microbiota,modelling
The best wearable heating system on the market. Together with strong clothing brands. (MAXHEAT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 2762708.75
EU funding (EUR): 1933896.13
Participants: 1
Project status: CLOSED

Inuheat is an innovative Swedish company who focuses on developing wearable heating systems which can be easily integrated in clothing. Our business strategy is to associate with leading clothing brands who implement our technology in their clothes. With a consolidated team of 12 engineers, developers and sales experts, our aim is to become the global standard in wearable heating technologies. Available wearable heating systems face multiple limitations, mainly the need for costly adaptations of manufacturing lines, a high price and low comfort, durability and efficiency. In 2016, Inuheat started the commercialisation of the Inuheat Wearable Heating Platform (IWHP), an innovative wearable heating system with advanced features allowing an easy implementation into standard clothing manufacturing equipment. The IWHP was introduced in 8 sock lines commercialised by Seger arousing great interest among final users and clothing brands. MaxHeat is the next step in Inuheat’s product pipeline. It will help outdoors enthusiasts and workers to keep warm by offering an affordable, easy to implement wearable heating system providing comfort, durability (3 years) and efficiency (8 hours battery life) while enabling full product traceability and a disruptive 2-way communication channel with the final users of the garments through a cloud network. MaxHeat has reached a TRL7 and is protected by 2 patents. Through MaxHeat project we aim to up-scale our production and fully develop MaxHeat cloud network. MaxHeat scale up will allow us to bring our production to Sweden, creating jobs and contributing to the development of the European industry. A strong commercialisation strategy will guarantee MaxHeat successfully reaches its target end users (clothing brands and final users of the heated garments), expanding our client base and sales. The market for smart textiles like MaxHeat is booming (33.6% CAGR) and is expected to reach €7.1 billion by 2022 creating a unique market opportunity.

Keywords: heated clothing,heated garments,smart textiles,smart clothing,advanced textiles,advanced fabrics,textile production,apparel
Valuing the socio-cultural and economic contributions of small-scale fisheries to coastal communities (SSF-value)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-04-01
End date: 2024-10-21
Duration (months): 33.0
Total project cost (EUR): 120699.36
EU funding (EUR): 120699.36
Participants: 1
Project status: SIGNED

In the EU, more than 80% of the fishing fleet is composed of small vessels less than 12 m of length. These vessels belong to the so called Small-Scale Fisheries (SSF) sector that provides around 100,000 direct jobs for fishers and a similar number of indirect jobs for women. Besides providing employment, small-scale fishers in the EU land annually around 2 million tons of high quality marine food valued in ca. EUR 2,6 billion. Despite these figures, the national economic contribution of SSF in terms of shares to country’s GDP, is generally low in comparison with large scale commercial fisheries. This low input to national economies usually masks the genuine societal contribution of SSF, which lies at the interface between socio-cultural and economic benefits to rural coastal communities. This project aims to identified and valuate these socio-cultural and economic contributions of SSF to rural communities in the Galician coast of Spain. Without these information, the scientific evidence for an ecosystem-based fisheries management that integrates ecological, social and economic objectives is deficient, and decisions for fisheries policies based on this incomplete knowledge risk producing adverse impacts to society. Applying an inter and trans-disciplinary methodology involving scholars from social and economic sciences and the actively participation of stakeholders, the objectives of this research are a) to identify the socio-cultural and economic contribution of Galician small-scale fisheries (including contribution of women) to coastal communities using a wellbeing and an economic approach, b) to estimate the value of the socio-cultural and economic contributions of SSF using economic valuation tools, c) to co-develop indicators that encompass socio-cultural and economic data for monitoring and evaluating impacts regarding quota allocation of marine rersouces to the SSF's fleet, and d) to communicate the contributions that flow from SSF inside and outside academia.

Keywords: socio cultural,small scale fisheries,economic valuation,wellbeing,coastal communities,sustainable development,transdiciplinarity,fisheries management
EuroPean trAining NetwOrk on Rare eArth elements environMental trAnsfer: from rock to human (PANORAMA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,Germany,Italy,Italy,Spain,Belgium,France,France,Portugal
Call: Innovative Training Networks (H2020-MSCA-ITN-2019, 2019)
Start date: 2020-06-01
End date: 2024-05-31
Duration (months): 48.0
Total project cost (EUR): 3877526.16
EU funding (EUR): 3877526.1599999997
Participants: 10
Project status: SIGNED

As Rare Earth Elements (REE) are crucial to a wide range of modern technologies regards to their unique properties, Europe expands its ability to obtain these strategic REE resources. Thus, several research and industrial projects were recently dedicated to the identification of potential REE stocks in Europe. However, the environmental risk exerted by the REE dissemination has so far received very little attention although disruptions of some REE biogeochemical cycles have been already evidenced. In that context, intensive and cooperative intersectoral researches are needed on REE environmental occurrence, behaviour, fate and their respective effects on natural resources (soils, waters and biota) and human health. The PANORAMA project is a unique multi- and interdisciplinary project aiming at (i) investigating the whole REE environmental behaviour including the characterization of sources, speciations and transfers throughout the different environmental compartments and sensu lato associated effects onto environmental health, as well as (ii) gaining valuable knowledge for applications in friendly environmental REE life cycle. For the 1st time PANORAMA gathers the competencies of (geo)chemists, (hydro)geologists and (eco)toxicologists, working in 14 academic and 4 private partners to enroll and train 15 Early Stage Researchers (ESRs). The project will combine training and cutting-edge research tools through coupled field/ analytical/experimental/modeling approaches. The strong blend of academic and non-academic sectors in the consortium will give the ESRs a unique chance to develop a wide set of fundamental research, technical and transferable skills (e.g. research integrity, communication and dissemination, career development and innovative technology), thus preparing them for long-time employment in either the academic, industrial, commercial or policy sectors and pave the way for high-level long-standing intersectoral collaborations within a European framework.

Keywords: rare earth elements,emerging pollutant,experimentation,bioassay,modelling,transport,speciation,bioavailability,reactivity
Centre for ExcelleNce in TerRItorial management and Cadastre (CENTRIC)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Framework Partnership Agreement
Countries involved: Italy,Germany,Belgium,Romania,Luxembourg
Call: Teaming (H2020-WIDESPREAD-2014-1, 2014)
Start date: 2015-04-29
End date: 2020-04-28
Duration (months): 60.0
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 8
Project status: CLOSED

Unlike most European countries, Romania does not have yet a general cadastre. Such a deficiency represents a critical element for the economy of the country, since it makes legal contracts, such as land purchasing, very difficult to be implemented. Starting from such a complex scenario, CENTRIC aims –in the long term- at the creation in Romania of the new Centre of Excellence on territorial management and cadastre. The future Centre will focus on related domains of great relevance, such as: 3D/4D geospatial data, linked geospatial data, land classification, remotely sensed data, etc. In particular, the goal of phase 1 of the project (the 12 months CSA) is to prepare a very detailed business plan leading, during phase 2, to the establishment of the Centre including: a long-term vision and the mission of the Centre, a detailed SWOT analysis of the domain of territorial management and cadastre in Romania, a long-term scientific and innovation strategy, a market analysis, the Business Concept of the Centre, the analysis of possible cooperation, strategic alliances and long-term partnerships, the operational and financial plan of the Centre, to define a strategic growth roadmap. Furthermore the project will also aim at the creation of a suitable ecosystem at the national Romanian and EU level, through a number of capacity building and dissemination activities. The whole project has been based on the creation of long-lasting (beyond the 5-years duration of the overall “Teaming” project) joint venture between partners from both advanced and low performing countries, including institutional cooperation among the Romanian Cadastre agency and the counterpart in Trentino Italy considered as a best practice at the EU level. The project is aligned with the Romanian Smart Specialisation Strategy and it has received a clear commitment from the Romanian Government to provide financial resources for infrastructural and equipment costs for phase 2.

Keywords: cadastre,territorial management,3d geospatial data,capacity building,research and innovation agenda,strategic growth roadmap
European City Calculator: Prospective modelling tool supporting public authorities in reaching climate neutrality (EUCITYCALC)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Italy,Germany,Belgium,Croatia,Belgium,Latvia,France,France,Czechia,Czechia,Portugal
Call: Supporting public authorities in driving the energy transition (H2020-LC-SC3-EE-2020-2, 2020)
Start date: 2021-09-01
End date: 2024-08-31
Duration (months): 36.0
Total project cost (EUR): 1998571.25
EU funding (EUR): 1998571.25
Participants: 12
Project status: SIGNED

In order for Europe’s transition towards climate neutrality to succeed, cities need to be in the driving seat. European cities are at the forefront in addressing climate change, with many having committed to develop and implement SEAPs/SECAPs through initiatives such as the Covenant of Mayors. Many cities have also committed to become climate-neutral by 2050 or even earlier. Yet, despite ambitious short- and long-term commitments, only few cities have managed to translate plans into concrete implementation strategies with tangible decarbonisation pathways. In transitioning towards climate neutrality, cities have to overcome complex challenges that cannot be tackled with a business-as-usual approach. For this, cities need to be equipped with tools, information and skills that empower them to become local transition leaders. This is where EUCityCalc comes into play. Its objective is to support public authorities in planning towards climate neutrality through the prospective modelling approach of the European City Calculator webtool. The European City Calculator is an open-source, prospective modelling tool providing cities with a sectoral outlook on the type and ambition of measures they can take to achieve a transition towards climate neutrality. As a flexible model adapted to territorial specificities and reflecting the city governance, it supports cities in designing tailored transition pathways and policy scenarios. With the webtool at its core, EUCityCalc will support 10 pilot cities - Riga, Dijon Métropole, Mantova, Zdar, Palmela, Sesimbra, Setubal, Koprivnica, Varazdin, Virovitica - in developing and implementing scientifically robust, detailed and integrated pathways and scenarios towards climate neutrality. Through peer-to-peer learning, a multifaceted capacity-building and training programme and the engagement of local stakeholders in expert working groups, EUCityCalc will empower cities in devising a clear and concrete roadmap towards climate neutrality.

Keywords: energy and climate planning,climate neutrality,transition pathways,policy scenarios,multi level governance framework,prospective modelling,webtool,cities,energy agencies,peer to peer learning
Dark Ocean Cosmeceuticals -DOC-: The Cosmetical and Pharmaceutical Potential of Marine Dissolved Organic Matter (DOC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-04-01
End date: 2019-04-30
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

An ageing population as well as chronic and infectious diseases, pandemic threats and antimicrobial resistance are currently on the rise. As a consequence, increasing attention is paid to the development of novel drugs, treatments and personal care products. In this context, blue biotechnology offers an opportunity to explore the potential of the marine microbial world to produce biological active metabolites, which may support health and wellbeing. The general goal of this proposal is the extraction and identification of biologically active substances in one of the largest reservoirs of organic material on Earth: the recalcitrant marine dissolved organic matter (RDOM) pool. This pool is an unexplored potential source of bioactive substances. For this purpose, the RDOM will be extracted from (1) one of the oldest water masses of the global ocean located at intermediate depths of the North Pacific and (2) the reworked DOM of marine sediments porewater in the North Sea. A comparative screen will be performed with the more recent surface oceanic water of the North Pacific. The antioxidant, immunostimulant and antitumoral potential of these DOM samples will be explored to evaluate possible cosmetical and pharmaceutical suitability. The DOM molecular diversity and features identified by mass spectrometry and nuclear magnetic resonance will be correlated with the different modes of bioactivity. This proposal will enable Dr. Catalá to broaden her expertise on molecular characterization of the DOM pool, to learn new methodologies of bioactive substances identification as well as to meet future challenges on marine natural product research, endorsed by the H2020 Societal Challenges of 'Health, Demographic Change and Wellbeing' and 'Marine Research and the Bioeconomy'. This combination of expertise is unique, and thus will be a milestone in Dr. Catalá career towards an independent scientist of high international visibility.

Keywords: marine cosmeceuticals,recalcitrant dissolved organic matter,marine resources,ageing,human wellbeing,bioactive substances
Quantum Sensing for Biology (QSB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United States,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-07-07
End date: 2020-07-06
Duration (months): 36.0
Total project cost (EUR): 269857.8
EU funding (EUR): 269857.8
Participants: 2
Project status: CLOSED

Modern physics has contributed to the development of powerful instruments and diagnostic tools for biology and medicine, with a direct impact on both our well-being and life expectancy. Today, it is timely to ask if the novel field of quantum information is ready to provide new methods for the life sciences. This proposal makes a step in this direction, introducing non-invasive quantum techniques for experimental biology, with potential applications to biomedical imaging. My goal is to show how quantum correlations (entanglement or discord) can be exploited to realize a fully non-invasive form of spectroscopy, which can be safely applied to fragile materials, such as photo-degradable biological samples (DNA/RNA) or in-vivo human tissues. These objectives are not met in today’s biology labs, where UV-light photometry heavily damages DNA/RNA samples, or in public hospitals, where X-ray scans expose patients to significant radiation doses, with non-negligible risks of cancer. The basic rationale behind the use of quantum correlations relies on their superior capacity to detect small variations in the absorption properties of the materials, even when only a few photons are employed. By exploiting this remarkable feature, I will prove the possibility of non-invasive testing of biological samples. My central task will be the design of a practical model of a quantum-enhanced photometer which is fully based on continuous-variable systems. This design will involve the extension of quantum sensing and metrology to a more advanced double-box formulation where two channels, representing seeded and blank samples, are simultaneously probed. The realization of such a quantum-enhanced instrument would allow for real-time continuous measurements of organic molecules and nucleic acids without any photo-degradation.

Keywords: quantum sensing,quantum measurements,quantum entanglement,quantum technologies,quantum hypothesis testing,non invasiveness,biology,spectrophotometers,spectroscopy
How the striatum contributes to visual-selection (STRIAVISE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Australia,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-10-01
End date: 2022-05-15
Duration (months): 36.0
Total project cost (EUR): 276107.4
EU funding (EUR): 276107.4
Participants: 2
Project status: CLOSED

The brain is limited in information-processing capacity, and must selectively prioritise neural representations of the external stimuli that are most relevant for one’s current goals, i.e. apply attention to the stimulus (visual-selection). Predictions about likely future sensory inputs help determine which stimuli are prioritised. Although we know that frontal and sensory cortices comprise key parts of a system that represents prioritised visual information, we are only just beginning to understand how predictions influence the activity of this system, or which neural substrates encode such predictions. The striatum is an excellent candidate neural substrate to underpin the influence of predictions on visual representations, even though its role in visual-selection has barely been considered. The core aim of this proposal is to investigate the scope of striatal contributions to the function and dynamics of the brain networks that underpin visual-selection. Neuroimaging (MRI, DTI), neuromagnetic (MEG), and deep-brain-stimulation (DBS) approaches will be convergently applied to i) provide a high-resolution functional map of the striatum when predictive contexts are available to guide visual-selection performance, ii) provide a rich spatial and temporal characterisation of striatal influence on the brain networks underpinning visual-selection, and iii) go beyond the limitations of correlative measures by identifying the causal influence of the striatum when predictions influence visual-selection. The gained precise understanding of how the brain instantiates this influence will not only advance our theoretical understanding of the nature of sensory experience, but also carries the potential to shed insights into the cognitive difficulties faced by patients with striatal dysfunction such as in Parkinson’s disease, ADHD, and schizophrenia, thereby paving foundations for new interventions.

Keywords: striatum,prediction,attention,magnetic resonance imaging,magnetoencephalography,deep brain stimulation