Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
PNEUMOSIP (PNEUMOSIP)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Spain
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-2-2015, 2015)
Start date: 2015-11-01
End date: 2019-02-28
Duration (months): 40.0
Total project cost (EUR): 3389912.5
EU funding (EUR): 3389912.5
Participants: 1
Project status: CLOSED

PneumoSIP project aims to be the first fully automated device in the POC market for the fast quantitative aetiological diagnose of Community-Acquired Pneumonia (CAP) also analysing antibiotic resistances to enable the most appropriate treatment for each infected patient. CAP is known to affect about 1/1,000 of the adult population per year, being even higher in the elderly and children populations. It is the fourth case of death in the world, and the leading cause of death in child population under 5 years old. The causal relationship between pathogens and pneumonia has been clearly established, being Streptococcus pneumoniae, Haemophilus influenzae type b (Hib) and the respiratory syncytial virus (RSV) the main pathogens responsible for CAP in Europe. Antibiotic therapy is the mainstream treatment for CAP, and the appropriate treatment involves starting empiric antibiotics administration within 8 hours of hospital arrival. Given this time constrain, traditional methods for diagnosing the aetiology of CAP have been discarded for CAP guidelines due to the slowness in sample to results. Another complication is that S. pneumoniae is a common colonizer of the nasopharynx (up to 70% of healthy population acts as a host), making the simple detection of the bacteria a useless diagnostic method. Thus, clinicians need rapid and accurate quantitative tests capable of identifying infectious agents and their potential antibiotic resistances. Therefore, PneumoSIP project aims to be a compact Respiratory Infectious Diseases diagnostic device providing fast quantitative identification of pathogens involved in CAP, enabling faster and more specific treatments. PneumoSIP seeks to combine laboratory standard precision with the simplicity required for POC applications. The market for PneumoSIP system is the POC market, concretely the Infectious Disease POC testing segment. The POCT segment was valued at $415.4 million in 2012 where Pneumosip will greatly impact.

Keywords: a cost effective solution for the rapid diagnostic of pneumonia
REGULATING STAFF ENHANCEMENT IN ORGANISATIONS (GLASNOST) (GLASNOST)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-03-15
End date: 2020-03-14
Duration (months): 24.0
Total project cost (EUR): 165598.8
EU funding (EUR): 165598.8
Participants: 1
Project status: CLOSED

My project aims to assess the impact of human enhancement technologies used at work onto employees and their performance. Indeed, the use of human enhancement technologies in organisations can shape the fu-ture of work, i.e. how one performs at work, how one feels at work, how one relates to others and managers. It has implications in terms of employee well-being and health. My project will promote the consideration of ethical issues in the implementation of technologies used to enhance the performance of individual employ-ees in organizations. It will first look at how organisations and stakeholders consider ethics in the way they implement the use of enhancement technologies, and then it will consider the role of ethics in shaping em-ployee acceptance and experience of the technology. Based on these elements, I will design together with stakeholders guidelines for the implementation of human enhancement in the workplace and a policy brief. The nature of this project is grounded in Ethics and Information Systems Management (IS), while being poli-cy-driven. Mixing these skills will provide an innovative look on theories of acceptance in IS, a field that traditionally understands ethics as ‘privacy’. Holding a PhD in IS and a master’s degree in Political Sciences, I have expertise in investigating organisations, policy, as well as users’ perception of technology. However, I need to get training in Ethics in order to integrate the forms of ethical assessment and dimensions of ethics to the IS theory. I will complete this research while hosted at the Philosophy Department of the University of Twente (UT) and supervised by Prof. Philip Brey, which will allow me to grow expertise in applied ethics and ethics of technology, and through a 6 month secondment in Dublin City University (DCU) with an IS professor – Regina Connolly.

Keywords: information systems,wearables,technology acceptance,q methodology,business ethics,applied ethics
eLTER Preparatory Phase Project (eLTER PPP)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Coordination and support actions
Countries involved: Austria,Israel,Germany,Spain,Italy,Germany,Bulgaria,Finland,Greece,Romania,Slovakia,Sweden,Switzerland,Norway,Serbia,Belgium,Hungary,Poland,Slovenia,Latvia,France,Czechia,Netherlands,Denmark,Portugal,United Kingdom
Call: Preparatory Phase of new ESFRI projects and early phase support to ESFRI high strategic potential areas (H2020-INFRADEV-2019-2, 2019)
Start date: 2020-02-01
End date: 2025-01-31
Duration (months): 60.0
Total project cost (EUR): 4000000.0
EU funding (EUR): 4000000.0
Participants: 30
Project status: SIGNED

eLTER RI is a pan-European Research Infrastructure planned to be operational in 2027. It has been built on the basis of existing national investments over several decades in the context of dedicated networks and ecosystem, critical zone and socio-ecological research projects. 162 Research Performing Organisations support the eLTER RI Science Case through a signed MoU, and 19 countries have formally provided political support to establishment of eLTER RI. The eLTER RI intends to create scientifically sound information required in response to grand societal challenges, while working as a distributed RI in the most cost-efficient way. It will continuously enhance its services and in-situ facilities to meet the needs of stakeholders as to emerging research challenges. Thereby, it will bring Europe to a globally leading role in ecosystem sciences. eLTER PPP will establish the vision and mission, strategic collaboration schemes and impact analyis of the RI; plan, consolidate with shareholders and start to implement the governance structures, coordinate a smooth transition from preparation into operations by establishing a legal entity, and by clearly identifying risks and risk reduction measures; prepare the cost benefit analysis, full Cost Book of the RI, and the financial plans for the mid-term and long-term perspective, and consolidate them with the shareholders; conclude the requirements of the RI to be met by the Central Services, identify the host for the Head Office, and the scope and decision making processes for hosting other central service components; finalise the technical specifications of eLTER RI concerning National Research Infrastructure design, eLTER Standard Observations and site categories, and establish a site labelling process; and develop and set up communication, dissemination and marketing structures or seamless continuation in eLTER RI, and engaging the eLTER scientific user community and other user groups beyond the project life time.

Keywords: long term ecosystem research,elter,critical zone,socio ecological research,ltser,services,environmental research infrastructure,in situ,research,governance,legal,financial,user
Cholesterol metabolism as a driver of prostate cancer aggressiveness (ACM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-04-01
End date: 2017-03-31
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

According to the WHO, prostate cancer (PCa) is the most common cancer in men in the European Union (EU). The current view of cellular transformation and cancer progression supports the notion that cancer cells must undergo a metabolic reprogramming in order to survive in a hostile environment. Tumors are not homogeneous entities, and most cancers retain a differential fraction of cells with increased self-renewal capability (cancer stem or initiating cells), that accounts for recurrence and resistance to therapy. While we know more about the metabolism of tumor cells and its implication in cancer, our knowledge about the metabolism of cancer-initiating cells remains insufficient. Obesity is associated with increased risk of prostate cancer metastasis and death. On other side, statins treatment reduces the risk of PCa, indicating that cholesterol might have a role in the onset of the disease. Overweight and obesity rates in EU affect 50 and 20% of the population respectively. Therefore, it is critical to define the role of environmental factors such as nutrition and “lifestyle” for cancer prevention. Preliminary studies in our lab indicate that cancer initiating cells are highly enriched in cholesterol synthesis genes and their sphere formation capacity is dependent on cholesterol synthesis. We hypothesize that an active cholesterol metabolism is essential for prostate cancer-initiating cell function, and that the use of cholesterol synthesis inhibitors might target this subpopulation of aggressive cancer cells. I will use a combined transcriptomic and metabolomic approach to define the alterations of cholesterol metabolism. I will study the mechanisms by which cholesterol metabolism regulates CIC function. I will study the feasibility of therapeutic targeting of cholesterol metabolism in prostate cancer using a well established mouse model. And finally, I will do a prospective associative study of statin treatment with CICs markers expression in patients.

Keywords: prostate cancer,metabolism,cholesterol,fatty acids,statins,cancer initiating cells
Current European and Cross-National Comparative Research and Research Actions on Migration (CROSS-MIGRATION)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Coordination and support actions
Countries involved: Austria,Italy,Italy,Italy,Austria,Germany,Belgium,Poland,Switzerland,Norway,Belgium,France,Netherlands,Netherlands,United Kingdom,Portugal
Call: Current European and cross-national comparative research and research actions on Migration (H2020-SC6-REV-INEQUAL-2017, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 1999018.0
EU funding (EUR): 1999018.0
Participants: 17
Project status: CLOSED

Migration and the characteristics which constitute its parameters, dynamics and complexities comprises one of the most paramount matters in contemporary Europe. Under these designated circumstances, the necessity of relevant, concise, and useful knowledge are prerequisites for the design of efficient and constructive policies. Although particular databases such as EUROSTAT and OECD offer valuable insights into these migratory dynamics, a comprehensive, efficient and integrative database which synthesizes, categorizes and maps out the vast analytical accounts on migration throughout Europe is non-existent. This project, bringing together 16 leading research institutions, networks and policy institutes throughout Europe, aims to proficiently fulfill this gap crucial for policy-purposes through the construction of a central migration hub. This hub will be of instrumental value due to its capability to operate as a key grammar in the design of current and future policy. Essentially, it accumulates and consolidates past, present and future migration research through providing an extensive yet succinct overview of migration drivers, infrastructures, flows, and policies, allowing for an improved systematic understanding of the factors that constitute the interaction between these analytical categories. The accessibility, accumulation and integration of research in one hub will be an integral element for improved policy making as it concentrates and visualizes relevant data – thereby facilitating information acquisition in pursuance of policy oriented goals. As of such, a continuous research-policy dialogue is prevalent throughout the construction of the hub, an insight which enables its users to visualize and develop migration scenarios- entailing a classification system for migration research. Consequently, the project aims to shape a strategic research agenda on migration as it will identify gaps, overlaps and connections within the available stock of migration research

Keywords: international migration,migration research hub,migration scenarios,research policy dialogues,strategic research agenda,migration classification system,research synthesis
Centre of Excellence for Advanced Technologies in Sustainable Agriculture and Food Security (ANTARES)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Specific Grant agreement
Countries involved: Serbia,Serbia,Netherlands
Call: Teaming Phase 2 (H2020-WIDESPREAD-01-2016-2017-TeamingPhase2, 2016)
Start date: 2017-03-01
End date: 2025-02-28
Duration (months): 96.0
Total project cost (EUR): 14003473.75
EU funding (EUR): 14003473.75
Participants: 3
Project status: SIGNED

Agriculture is facing enormous challenges today. Not only does it have to provide enough safe and healthy food for the ever-increasing Earth’s population, it is also expected to offer alternatives to fossil fuels and to protect the non-renewable resources such as soil, water and energy inputs. ANTARES aims to evolve BioSense Institute from Serbia into a European Centre of Excellence (CoE) for advanced technologies in sustainable agriculture, by implementing a detailed business plan prepared during ANTARES Phase 1. This endeavor is supported by the participation of the Serbian Ministry of Education, Science and Technological Development who will provide both institutional and legislative support, as well as by a strong commitment of the Republic of Serbia to provide co-financing of 14 mil . The participation of DLO from the Netherlands, the leading European institute for applied and market-driven research in the agrifood sector will secure that the know-how and experience of the highest European standards are transplanted to Serbia. ANTARES builds upon the complementary expertise of BioSense and DLO: the synergetic combination of ICT and agricultural knowledge will strengthen the competitive positions of both institutions and provide answers to challenges that go far beyond borders of any single country. ANTARES envisages a long-term strategic cooperation between DLO and the new CoE, relies on a well-developed joint strategic research agenda and on a documented financial analysis that proves the long-term sustainability and growth of the new CoE beyond Teaming funding. CoE’s mission and vision are aligned with needs of European and Serbian society and focus on science for impact and economic growth. ANTARES is a smart investment, as it simultaneously helps an associated country to bridge the gaps with Europe through research and innovation, while at the same time contributes to safe and adequate food for future generations of Europeans.

Keywords: centre of excellence,advanced ict technologies,sustainable agriculture,food security,agrifood
Pioneering policies and practices tackling educational inequalities in Europe (PIONEERED)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Spain,Germany,Ireland,Switzerland,Norway,Finland,Lithuania,Hungary,Luxembourg
Call: Enhancing access and uptake of education to reverse inequalities (H2020-SC6-TRANSFORMATIONS-2020, 2020)
Start date: 2021-03-01
End date: 2024-02-29
Duration (months): 36.0
Total project cost (EUR): 3500000.0
EU funding (EUR): 3500000.0
Participants: 13
Project status: SIGNED

The main objective of the RIA PIONEERED is to determine research-informed policy measures and identify pioneering policies and practices to mitigate (intersectional) inequalities in access to, uptake and completion of education, both in formal and informal educational settings. This involves a) mapping emerging and existing sources of educational inequalities over the course of educational careers from early childhood to tertiary education, b) mapping responses to inequalities as pioneering policies and practices from a comparative perspective, and c) synthesising the findings and identifying the most promising tools, pioneering policies and practices within and across European countries. This is achieved by an interdisciplinary and mixed-method strategy including multilevel, intersectional, and life course approaches. The research design relies on four key pillars: A first pillar aims at developing an innovative methodological framework and reviewing the state-of-research. A second pillar centres on a policy analysis on which inequalities and vulnerable groups are addressed by national (or regional) policies, and how polices attempt to reduce inequalities. A third pillar focuses on analyses of new and existing data to identify intersectional inequalities throughout educational careers and drivers of such advantages and disadvantages. A fourth pillar centres on practice research in schools and informal educational settings and analyses the ways through which educational inequalities are tackled by different actors. With these objectives and comprehensive research strategy, PIONEERED thoroughly addresses the challenges identified in the H2020 work programme Europe in a changing world – Inclusive, innovative and reflective societies by providing evidence-based and customised policy tools, specific to various stages of education and target groups in order to enhance access to education among vulnerable children and youth and to reduce educational inequalities.

Keywords: access to education,educational attainment,gender,socio economic background,educational practices,interdisciplinary research
Developing Optimal and Open Research Support for the Black Sea (DOORS) (DOORS)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Unlocking the potential of aquatic living resources
Action type: Research and Innovation actions
Countries involved: Ukraine,Spain,Ireland,Spain,Germany,Spain,Spain,Italy,Germany,Belgium,Romania,Moldova, Republic of,Türkiye,Türkiye,Türkiye,Bulgaria,Russian Federation,Bulgaria,Greece,Bulgaria,Greece,Greece,Romania,Georgia,France,France,France,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: Towards a productive, healthy, resilient, sustainable and highly-valued Black Sea (H2020-BG-2020-2, 2020)
Start date: 2021-06-01
End date: 2025-05-31
Duration (months): 48.0
Total project cost (EUR): 9795350.0
EU funding (EUR): 9000000.0
Participants: 38
Project status: SIGNED

DOORS will bring the four pillars of the SRIA into reality, turning the challenges into opportunities for a highly valued Black Sea. It will harmonise research and provide the infrastructure to better understand the Black Sea, particular ecosystem characteristics, develop the framework to support Blue Growth and early development of start-ups, and provide evidence to inform policy and behavioural change. To reach its ambitious objectives, the project team will work closely with stakeholders from the start to develop an open research system and establish a framework to support continuous stakeholder dialogue. DOORS will implement three Work Programmes: a System of Systems to harmonise approaches and provide an accessible data repository, a Blue Growth Accelerator to support enterprise, and Knowledge Transfer and Training to share best practice and build capacity. These will: • Engage stakeholders through communication, dissemination and training activities to raise awareness, build capacity and foster a stronger Black Sea identity • Harmonise data collation, analysis and access to optimise data use in decision and policy making • Strengthen the Black Sea scientific network through new collaborations, and bridge the gap between science and policy • Provide a range of products to support Black Sea innovation and enterprise DOORS will have long-lasting impact by giving stakeholders in the region the skillsets and understanding to: • Implement key policies and legislation • Improve environmental quality and reduce pollution risk • Design measures to mitigate pollution and remediate historically contaminated areas • Become resilient communities • Realise and sustainably develop potential economic growth for future well-being • Build capacity in existing industries, develop new start-ups and become actively involved in delivering Blue Growth • Create ocean informed citizens to better understand Black Sea’s potential

Keywords: system of systems,blue growth,knowledge transfer and training,stakeholder involvement,climate change,ecosystem services