Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Smart Planning and Safety for a safer and more robust European railway sector (PLASA)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: European rail initiative
Action type: Research and Innovation actions
Partnership: Shift2Rail (Art-187)
Countries involved: Germany,Italy,Germany,Germany,Sweden,Sweden,France
Call: Integrated Mobility and Safety Management (H2020-S2RJU-CFM-2015-01-1, 2015)
Start date: 2016-09-01
End date: 2018-08-31
Duration (months): 24.0
Total project cost (EUR): 349453.75
EU funding (EUR): 349453.75
Participants: 8
Project status: CLOSED

PLASA represents the 1st proposal of the Shift2Rail members referred, according to MAAP, to the following Work Areas within the Cross Cutting Activities: - WA 3.1: Safety - WA 4.1: Smart Planning The PLASA project aims at significantly increasing customer experience and system robustness in the European rail sector. On the one hand, it improves planning activities of various stakeholders in the railway system by means of precise railway simulation and, on the other hand, it provides a methodology to manage the safety of the railway system based on risk assessment. This will be achieved by an holistic approach involving partners of the rail industry, the operators and universities.

Keywords: simulation,safety
Applied mathematics for risk measures in finance and insurance, in the wake of the crisis (WAKEUPCALL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: Spain,Italy,Spain,Spain,Netherlands,Netherlands,Netherlands,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 1522617.12
EU funding (EUR): 1522617.12
Participants: 12
Project status: CLOSED

The EID WAKEUPCALL has been set up with the knowledge that, in the WAKE of the financial crisis, a reconsideration of fundamental assumptions that have been standard in the mathematical models for the valuation of financial and insurance products, like CALLs is taking place. The crisis alerted to reiterate models, assumptions and computations. It is now better understood that the usual paradigm, in which financial risks can be mitigated, spread, or even hedged away perfectly, is too simplistic for markets under stressed conditions. Lead by the Basel Committee on Banking Supervision, financial and insurance institutions are currently implementing new paradigms regarding risk management. Many of the updates in the risk measures involve sophisticated mathematics. In this sense, the crisis has provided important feedback on appropriate directions for the required mathematical improvements. As regards to hedging and risk mitigation, which are important steps in the risk management chain, nowadays even the hedging of basic financial instruments has become a complicated task. More sophisticated models are needed if hedging programs are to remain effective under financial stress. We wish to bring together academic researchers in financial mathematics and high level professionals in financial and insurance industries, discuss and interact by means of early-stage researchers (ESRs). We are interested in the mathematical models, as well as in advanced solution techniques used for pricing and risk measurement. We wish to educate young experts in modern risk measures and management. Advanced courses by academic and professional lecturers will be selected for the education of the ESRs. We will additionally work on providing entrepeneurial skills to ESRs as they will have a unique knowledge of applied mathematics on practically relevant research questions in computational finance. All ESRs will produce software, according to latest standards in high performance computing.

Keywords: numerical mathematics,computational finance,risk measures,asset dynamics,gpu computing,efficient valuation algorithms
Multiscale modeling and simulation approaches for biomedical ultrasonic applications (MULTraSonicA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Spain,Slovenia
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2021-12-01
End date: 2026-11-30
Duration (months): 60.0
Total project cost (EUR): 2490750.0
EU funding (EUR): 1535500.0
Participants: 2
Project status: SIGNED

Ultrasound-guided drug and gene delivery (USDG) enables controlled and spatially precise delivery of drugs and macromolecules, encapsulated in microbubbles (MBs) and submicron gas vesicles (GVs), to target areas such as cancer tumors. It is a non-invasive, high precision, low toxicity process with drastically reduced drug dosage. These advantages open doors to numerous biomedical applications, from sonothrombolysis to blood–brain barrier opening. However, the progress and deployment of this technology is subject to extensive experimentation and heuristics. The proposal aims to develop a virtual environment to quantify and optimize USDG and in particular the MBs and GVs utilized as drug carriers and contrast agents. Their type and concentration, and interface with ultrasound (US) are critical to the success and efficiency of USDG. State-of-the-art USDG systems operate in a narrow range of empirically-tuned US parameters. This empiricism entails severe risks and limitations for clinical applications and delays the adoption of this potent technology. I propose a computational framework that would allow for controlled testing, data-driven quantification of uncertainties, and a rational optimization of experimental US parameters. The framework will rely on submicron resolution modeling and simulation of cavitating MBs and GVs interacting with US. Limitations of existing models based on continuum theory preclude an accurate description of cavitation, drastically degrading the prediction of drug delivery outcomes. I will develop new, data-informed mesoscopic models of US contrast agents, capturing their rheological and acoustic behavior. Specific interactions of US and agents at a submicron level will be included by harnessing novel multiscale methods that enable seamless propagation of US from the macro to microscopic level. The proposed framework will be integrated with experimental efforts to advance USDG across biomedical applications.

Keywords: pacs2010 02 70 ns molecular dynamics and particle methods,43 35 c ultrasonics,quantum acoustics,and physical effects of sound,43 35 wa biological effects of ultrasound,ultrasonic tomography,43 40 ey vibrations of shells,43 40 ng effects of vibration and shock on biological systems
Veterinary Decision Support System by Rapid Bacterial Infection Detection (RAID) (RAID)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Hungary,Hungary
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-04-01
End date: 2021-03-31
Duration (months): 24.0
Total project cost (EUR): 2520625.0
EU funding (EUR): 1764437.5
Participants: 2
Project status: CLOSED

Development of multidrug-resistant bacteria represent an increasing threat for human and animal health. These bacteria strains are developing mainly due to the unjustified use of antibiotics both for humans and animals. That is why, from 2013 in the European Union, antibiotics can only be added to animals for treatment (not preventive!) purposes, after unambiguous diagnosis of the disease by a veterinarian. This process is beneficial for supressing antibiotic use, but results in high costs and time loss for farmers. The incontrovertible proof of bacterial infection is carried out by culturing method, which takes 24 to 72 hours and costs between 10-50 euros. Our innovation, RAID is Veterinary Decision Support System (RAID), does not require culturing and thus can detect bacterial infection within maximum 2 hours at affordable cost. We have successfully demonstrated our method with an independent veterinary examination under real conditions (TRL=7), developed a stepwise market introduction strategy: first, intensive poultry farming is targeted, as the bacterial infection is the most serious problem in this segment. Potential buyers have been identified, several of them expressed their interest to the project. We submitted a patent application about RAID method. In this phase 2 project, we aim to carry out all essential steps for market introduction: increasing the number of detectable bacteria to at least 50, increasing the reliability to at least 98%, improving and automating sample processing method, establishing a mobile RAID laboratory for satisfying the need of small farmers and veterinarians, who cannot invest to buy large devices and using it for demonstration purposes, validating and certifying our method. We aim to refine our business plan and to obtain tangible commercial results at the end of the project, i.e. signed service contracts and purchase orders. The success of the project will promote the growth of the companies involved.

Keywords: bacterial infection detection
Plastic in the Ocean: Microbial Transformation of an ‘Unconventional’ Carbon Substrate (VORTEX)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Netherlands
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-06-01
End date: 2024-05-31
Duration (months): 72.0
Total project cost (EUR): 1999185.0
EU funding (EUR): 1999185.0
Participants: 1
Project status: SIGNED

Large quantities of plastics comprising a diverse set of hydrocarbon or hydrocarbon-like polymers are constantly released to the oceans. The impacts of plastics in marine environments are detrimental, as they are seemingly recalcitrant and harmful to marine life. The severity of this problem is gaining momentum because the untamed demand for plastics has led to an ever-increasing release of plastic to the sea. However, despite their seemingly persistent properties, they do not accumulate as expected, indicating a substantial sink for plastics in the ocean. Plastics are synthetic and thus rather new and ‘unconventional’ compounds in the marine realm, yet microbes can utilise plastics as carbon substrates. However, the potential for microbial degradation of plastics in the ocean as well as key factors controlling degradation kinetics are largely unknown and have been discussed controversially. Using innovative stable isotope assays, my preliminary research has shown that plastics can be degraded in marine sediments under aerobic as well as anaerobic conditions. Here I propose to further investigate the potential for marine plastic degradation by microbes in laboratory- and field-based experiments across a wide range of contrasting environmental boundary conditions. In the VORTEX project, we will use cutting-edge stable isotope labelling and stable isotope probing assays in combination with biogeochemical/microbiological and organic geochemical tools to trace isotopically labelled carbon from the plastic-substrate pools into microbial metabolites (e.g. CO2) and biomass (e.g. diagnostic lipid biomarkers, DNA/RNA). This will lead to a breakthrough in our understanding of microbial plastic degradation in the ocean because the proposed analytical approaches allow to quantify kinetics of microbial polymer breakdown, to identify and quantify the responsible microbes and degradation pathways, and to determine environmental conditions conducive for plastic degradation.

Keywords: microplastic,lipids,bioremediation,stable isotope labeling,stable isotope probing
Territorial Responsible Research and Innovation and Smart Specialization (TetRRIS)

Framework: Horizon 2020 — Science with and for Society
Programme: Integrate society in science and innovation issues, policies and activities in order to integrate citizens' interests and values and to increase the quality, relevance, social acceptability and sustainability of research and innovation outcomes in various fields of activity from social innovation to areas such as biotechnology and nanotechnology
Action type: Coordination and support actions
Countries involved: Germany,Spain,Germany,Spain,Belgium,Hungary,Finland,Finland,Netherlands,Netherlands
Call: Supporting the development of territorial Responsible Research and Innovation (H2020-SwafS-2019-1, 2019)
Start date: 2020-09-01
End date: 2023-08-31
Duration (months): 36.0
Total project cost (EUR): 1980437.5
EU funding (EUR): 1980437.5
Participants: 10
Project status: SIGNED

Territories and regions have become during the last decades increasingly important sources of economic and innovation activity. Concurrently, environmental and social concerns have become increasingly important and there has been expanding discussion on the responsibility aspects of research and innovation especially on the European level. The project aims to implement RRI in the territorial level. For this end, various European regions are participating in the project. The regions are from different parts of Europe giving an opportunity to make visible and compare different politico-economic contexts and their effects on the implementation of RRI. The project will: a) Map and analyze the territorial systems to understand what is the current role of RRI, and what are the drivers and barriers for a RRI related transition; b) Co-create with the stakeholders mechanisms and supporting elements for the increasing implementation of RRI; c) Support the organization of the pilots in the implementation of RRI; d) Organize opportunities for territorial actors to learn and have peer support from other regions internationally; and e) Support dialogue between different levels of governance of research and innovation on RRI. As conceptual and theoretical frameworks to understand the functioning of the regional system and to support change in the system, the project will utilize innovation systems related theories together with theories of systemic and organizational change.

Keywords: regional innovation systems,responsibility,ethics,governance
EDGE MULTI SENSING FOR MEDICAL AND PHARMA APPLICATIONS (DETERMINATION)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2022-11-01
End date: 2024-10-31
Duration (months): 24.0
Total project cost (EUR): 3655312.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

EZMEMS provides DETERMINATION, a ‘Smart Disposable multisensor' that transform simple medical or pharma products (infusion lines, fittings, plastic bags, bioreactor, transportation line) into 'Smart products' in an easy and cost-effective way. The multisensor is non-invasive, has low footprint and provides robust multi sensing (pressure, flow, temperature, conductivity, viscosity, turbidity and pH) and fully wireless connectivity (no battery, no wires, energy harvesting) at the edge, making Internet of Medical Things possible. EZMEMS' multisensor technology is based on advanced polymeric multilayered matrix composite structure integrating conductive piezoresistive & structural elements. Each layer implements a specific function (mechanical layers, sensing layer, interconnection layer and integration layer). The integration layer can be modified according to the application requirements & to the polymer of the product. DETERMINATION can be fabricated in mass production facilities.

Keywords: energy harvesting,internet of medical things,embedded systems,multi agent systems,intelligent systems,smart disposable multisensor,polymeric multilayered matrix,pharma bioreactors,flow measurement,medical disposable devices,biocompatible integration,sopc,system on a plastic chip,micro electromechanical desing,edge multisensing,integrated circuit,electromechanical engineering
Approaching the maximum thermoelectric figure of merit of 2D materials by nanoengineering (CARMEN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

Nanoengineering techniques have been developed to reduce thermal conductivity (κ) and improve the thermoelectric figure of merit (ZT) of materials. However, both these strategies have had their own limitations. Firstly, due to the nanopatterns only reducing the κ in a single direction, is difficult to reduce the total κ of thermal isotropic materials. Secondly, when nanoengineering the material to increase ZT by lowering its κ, the nanopatterned sample with large porosity (> 0.5) can greatly remove its volume and suppress the electron mean free path, which would also significantly reduce the electrical conductivity (σ) and resulted in a low increase of the ZT value. CARMEN will overcome these limitations by taking two advantages of emerging two-dimensional (2D) materials, especially SnSe2: a high Seebeck coefficient of 500 μV/K at 298 K and a high anisotropic κ ratio of ~ 8.4. Therefore, nanoengineering 2D materials can reduce their κ to approach the maximum value of ZT with a limited reduction in σ. Additionally, the phonon drag of SnSe2 was first revealed by the applicant during a three-month research visit in the supervisor's group, which will be further investigated by CARMEN. To understand and exploit the thermoelectric properties of 2D materials, CARMEN will design, construct, measure, and explore nanopatterned SnSe2 to approach its maximum thermoelectric ZT value above room temperature and to manipulate the phonon drag in SnSe2 at low temperatures (1 - 273 K). The project is motivated in part by the urgent need for highly thermoelectric ZT materials to harvest waste heat from electronics, and in part by the fundamental quest toward understanding and manipulating the phonon-electron interaction in 2D materials. It represents an extraordinary training opportunity on complementary scientific and soft skills for the applicant and has transformational impact potential on flexible thermoelectric devices, thermal engineering, quantum technologies, and beyond.

Keywords: thermoelectricity,2d materials,phonon drag,phononic crystals,cryogenics,seebeck,thermal conductivity
ATTRIBUTION – DATA- ANALYSIS – COUNTERMEASURES – INTEROPERABILITY: ADAC.IO (ADAC.io)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Democracy and Governance
Action type: Research and Innovation actions
Countries involved: Sweden,Lithuania,Germany,Poland,United Kingdom,Netherlands
Call: Detecting, analysing and countering foreign information manipulation and interference (HORIZON-CL2-2023-DEMOCRACY-01, 2023)
Start date: 2024-02-01
End date: 2027-01-31
Duration (months): 36.0
Total project cost (EUR): 2519637.5
EU funding (EUR): 2519637.5
Participants: 7
Project status: SIGNED

The purpose of this project is to protect democracy in the EU by strengthening the ability to deny the intended effects of FIMI on society. This will be achieved with focused research that brings together some of the principal actors behind the intellectual and technical components of FIMI as it has been developed by the EEAS and other EU Institutions. We will work together to significantly develop upon current knowledge of how FIMI can be detected, categorised, analysed, shared, and countered. We will achieve this through a series of coordinated contributions to the DISARM Framework, the NATO-Hybrid COE Attribution Framework, STIX 2.1, OpenCTI, ABCDE, and the FIMI countermeasures toolbox. This approach acknowledges the importance of TTPs and common data handling standards to the ability to attribute FIMI actors, and further positions TTPs within the broader analytical processes that are necessary to developing countermeasures. In addition to establishing improved technical standards and operating procedures, we will generate research knowledge that can support better decision-making about FIMI countermeasures. For example, we will conduct research into the public impact of attribution, research methods for linguistic and visual analysis, develop the understanding of how cross-platform manipulation evades traditional analysis methods, as well as establishing a dataset of previous FIMI interventions. We include a specific component on gendered disinformation designed to better integrate gender into the technical formats. Finally, we will work closely with a community of practice that includes the EEAS, representatives of member states, civil society, and journalists/EDMO.

Keywords: attribution,disarm,countermeasures,journalism