Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Neo-PRISM-C: NEurodevelopmental Optimal-Predictors, Risk factors, and Intervention from a Systems approach to Maladjustment in Children (Neo-PRISM-C)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Cyprus,Belgium,Finland,Greece,Greece,Hungary,Hungary,Croatia,Netherlands,Netherlands,United States,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2018, 2018)
Start date: 2018-12-01
End date: 2023-08-31
Duration (months): 57.0
Total project cost (EUR): 3837148.2
EU funding (EUR): 3837148.2
Participants: 18
Project status: SIGNED

Mental health disorders pose a massive economic and societal burden. Emerging early in development and resulting in long-term disability, neurodevelopmental dysfunctions (NDD) compromise the quality of life of millions of Europeans. The purpose of the Neo-PRISM-C ETN is (1) to train Early Stage Researchers (ESRs) in applying the Research Domain Criteria, a novel framework for understanding psychopathology, to the study of the mechanisms and treatments of NDD. It aims (2) to train ESRs from multiple disciplines (psychology, neuroscience, data science) in state-of-the-art and transferable skills for innovating the study of brain-behavior relationships in NDD, in the context of a systems-based, trans-diagnostic theoretical frame. This ETN will also (3) support training in designing evidence-based, individualized treatments of learning, behavioral, and social maladjustment, bridging across diagnostic categories. Towards these goals, we have assembled a trans-sectoral European network with expertise in cognitive, social, educational, clinical, and emotion research and in training ESRs. Six research, training and management work packages (WPs) pursue these goals. WP1 comprises innovative projects, investigating risk and protective factors that span across NDD diagnostic categories (autism, learning, emotional difficulties) and linking to healthcare industry and education. WP2 examines systems-level brain development to identify biological substrates of specific dysfunctions. WP3 applies this knowledge to develop new multi-modal interventions to address domains of impairment. The academic, industrial and clinical partners collaborate across themes, offering ESRs project-specific secondments, supervision, workshops, summer school and courses on research, transferable and entrepreneurial skills. Neo-PRISM-C is expected to further understanding of NDD and improve the competitiveness of EU health professions, providing the market with highly-skilled researchers and clinicians.

Keywords: child,neurodevelopmental dysfunctions,brain development,learning disabilities,emotion regulation,autism,biomarkers,multi modal brain imaging,fmri,modelling,rdoc
Galileo dual frequency, 5G, IoT devices and services for Drones, Assets Management and Elite sport (GEONAV IoT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Innovation actions
Countries involved: Ireland,Poland,Poland,Poland,France,France,France
Call: EGNSS applications fostering digitisation (H2020-SPACE-EGNSS-2019, 2019)
Start date: 2019-12-01
End date: 2022-11-30
Duration (months): 36.0
Total project cost (EUR): 1880882.5
EU funding (EUR): 1316617.75
Participants: 7
Project status: SIGNED

The GEONAV IoT project aims at the development and delivery of precise ubiquitous positioning and navigation applications and services. The core activity of the project is to develop and industrialize the 2nd evolution phase of the GEONAV IoT solution, following NAVISP Element 2 outcomes (TRL7). GEONAV IoT is market driven with clear commercialization ambition. It aims to: - Use Galileo features that improve performances: Dual Frequency for an improved real-time positioning and TTFF; - Improve fusion with other positioning techniques thanks to innovative network fusion techniques with 5G; - Optimise power consumption thanks to TTFF improvements and GEONAV IoT algorithms; - Expand the range of market application with demonstration on 3 use cases: Elite sports (Rugby), Asset tracking and monitoring; Autonomous Drones based delivery system; - Set-up a European Industrialisation chain. The GEONAV IoT consortium is made of industrials and SMEs mastering the full industrial value chain. Our aim is to demonstrate the European production capacity of innovative EGNSS application based devices and services and accelerate their market take up. The project duration is 18 months, our ambition is to improve TRL up to 8-9. The addressable LBS and Drones markets are huge and Elite Sport will help for promotion on GEOANV IoT. Market take up per use cases is part of GEONAV IoT business plan. Expected revenues are promising: eg, in 2024 24m€ and 50 new jobs created. Ambition is to bring European industry as leader in LBS and drones Markets.

Keywords: galileo dual frequency,hydridization,security,drones,assets management and elite sport
An Anytime, Anywhere and Any-budget platform to boost the digital VIDEO marketing for SMEs (Traipler)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Italy
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-01-01
End date: 2018-04-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

TRAIPLER S.R.L. is an Italian SME established in 2013 by three young entrepreneurs and growing at a fast pace. After three years of challenging work, we achieved a significant turnover close to 680,000€ (2016) and we expect for the current year to almost double the turnover approaching us to 1,200,000€. Currently, we have 19 employees and we expect with this project generates 150 new job opportunities for our company. As a video digital content company, we have noticed that every day, millions of companies worldwide need to produce and publish nonstop quality video content into their social channels (i.e. Instagram, Facebook, LinkedIn, YouTube and TV channels) in order to communicate and relate digitally with their potential customers and grow in audience continuously. SMEs are the most affected in the process, since they frequently hire advertising agencies for a video-content production. This process needs high capital investement, requires months for its realisation and generates low brand awareness. To solve this situation, we have conceived Traipler, a Video Content Marketing and Digital Storytelling Platform specialized in video production and market content mainly for SMEs, born from the desire of illustrating stories concerning places, landscapes, people, ideas and projects without any actors, storyboards or scenographies behind. Traipler will lead us to generate an accumulated Revenue of 17M€ and a ROI of 2.5 by 2024; meanwhile this translates to us into 3,300 new clients worldwide by the same year. To achieve these figures, we have been supported by several companies and entities, highlighting Unicredit, Adcom, Convatec, Spark 44, Manetti & Roberts and the Ministry of Goods and Cultural Activities and Tourism – Reggia di Caserta.

Keywords: video,digital,social channels,smes,video content,production,brand awareness,platform
Promoting SINgle cell GEnomics to explore the ecology and evolution of hidden microeuKaryotes (SINGEK)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,Spain,Spain,Spain,Sweden,Sweden,Belgium,France,France,United Kingdom,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2015, 2015)
Start date: 2016-01-01
End date: 2020-05-31
Duration (months): 53.0
Total project cost (EUR): 3889393.2
EU funding (EUR): 3889393.2
Participants: 16
Project status: CLOSED

Environmental microbial surveys have revealed a remarkable diversity of microeukaryotic life in most ecosystems, the majority of which had previously escaped detection. From an ecological point of view this work highlighted our ignorance of critical microbial players in natural environmental processes, including primary production, biogeochemical cycling and trophic interactions such as parasitism and grazing. Consequently, our understanding of community function is partial, limiting our ability to study environmental change. While, from an evolutionary perspective, we are missing major components of the Tree of Life giving rise to a fragmented understanding of how major cellular functions have evolved. Single cell genomics (SCG), including single cell transcriptomics, is an emerging technology that has the potential to retrieve genomic information from individual uncultured microbes recovered directly from natural environments and promises to provide new tools to investigate microeukaryotes in unparalleled detail. The aim of this ITN is therefore to train a new generation of scientists with the highest expertise, in SCG, from the initial stages of cell sorting to genome sequencing and gene annotation, to the full exploitation of the data obtained. Such progress will allow the European research community for the first time to address critical ecological and evolutionary questions. SINGEK will drive training through research by both local and network-wide activities, secondments, and workshops, and by establishing an environment that extends far beyond each partner team. This training environment will also provide the transferable skills essential for successful career development. This network of well connected and highly qualified scientists with expertise in eukaryotic SCG will be ready to implement this technology beyond ecology and evolution to other fields such as biomedicine or biotechnology driving innovation across the EU.

Keywords: single cell genomics,bioinformatics,ecology,evolution,microbial eukaryotes
European Joint Doctorate in Biology and Technology of Reproductive Health (REP-BIOTECH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Joint Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Ireland,Italy,Spain,Spain,Belgium,France,United States,Netherlands,Japan
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) (H2020-MSCA-ITN-2015, 2015)
Start date: 2015-11-01
End date: 2019-10-31
Duration (months): 48.0
Total project cost (EUR): 3811469.04
EU funding (EUR): 3811469.04
Participants: 15
Project status: CLOSED

The main objective of the European Doctorate in Biology and Technology of the Reproductive Health (REP-BIOTECH) is to build a research, training and academic programme in the interdisciplinary domain of reproductive health and fertility. Basic knowledge of mechanisms involved in mammalian fertilization and embryo development provides useful strategies to improve food quality (by implementation of efficient and secure animal reproductive technologies), human health (by contributing to the control of reproductive diseases and epidemiologic factors) and human and animal fertility (by identifying target molecules for successful conception or contraception). REP-BIOTECH is a PhD programme with the aim of training a new generation of creative, entrepreneurial and innovative Early-Stage Researchers (ESRs). ESRs must carry out independent research on a specific topic to be awarded a European Joint Degree from 5 European Universities (Beneficiaries). The PhD project will be jointly supervised within a joint governance structure in which the beneficiaries as well as the partner organisations will be actively involved. The Doctorate programme will expose ESRs to different sectors and they will acquire a comprehensive set of transferable skills working in the specific research area relating to their doctoral thesis. The consortium has a proven track record in their area and they have a history of fruitful scientific collaboration. Moreover, giving the diversity amongst the participating institutions, the ESRs will be able to face current and future challenges in order to convert knowledge and ideas into products and services for economic and social benefit. The strength of the partnership lies in being a multidisciplinary group (animal and human fertility, reproductive health and reproductive technologies) within the cooperation of 7 different European countries, the collaboration of Universities from Japan and United States and partners from the non academic sector.

Keywords: fertility,reproductive health,reproduction
Perspectives for the Aeronautical Research in Europe (PARE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Coordination and support actions
Countries involved: Ukraine,Spain,Italy,Austria,Türkiye,Lithuania,Romania,Poland,France,Portugal,Portugal,Portugal
Call: Identification of gaps, barriers and needs in the aviation research (H2020-MG-2017-SingleStage-RTD-MOVE, 2017)
Start date: 2017-10-01
End date: 2020-12-31
Duration (months): 39.0
Total project cost (EUR): 1771981.25
EU funding (EUR): 1771981.25
Participants: 17
Project status: CLOSED

The overall objective of PARE (Perspectives for the Aeronautical Research in Europe) is to trigger collaboration between European stakeholders to support the achievement of the Flightpath 2050 goals, by providing yearly reports (and respective methodology) that assess the progress, gaps and barriers and propose suitable measures to close the remaining gap. The main outputs of PARE are three yearly reports on the “Perspectives for Aerospace Research in Europe” that use specific benchmarks to assess the progress towards each of the 23 Flightpath goals and the gap remaining. The assessment includes EU projects (Clean Sky, SESAR and others), national projects, academic and industrial research reports. Aspects like long-distance travelling and relevant emerging technologies from non-aeronautical sectors are focused, as well as greater participation from recent EU member states (e.g. in Eastern Europe) and associated countries (e.g Ukraine). The activities of Europe’s competitors (e.g. the U.S.) are also considered in PARE to assess: areas of EU leadership to be exploited; areas requiring specific effort in the EU to catch-up; areas of common interest for cooperation. PARE will contribute to fulfil the “Mobility for Growth” workprogramme with an assessment of progress in aerospace research, gaps and bottlenecks. The comprehensive yearly report (RC), can originate a public version (RP) and specific versions for academy and research (RA), industry, airlines and airports (RB) and certification authorities, international and professional associations (RC). The wide dissemination of each report will allow to collect feedback to improve the next one thus establishing the final reporting procedure that could be extended beyond the end of the project. Also addressed is the attraction of young talent and the increase in the participation of woman in aerospace including the preparation of a newsletter on exciting and attractive developments in aeronautics.

Keywords: flightpath 2050,acare,research and innovation,assessment,collaboration,associated countries,benchmarks
New markets technological positioning for ultra-high temperature latent heat energy storage (NATHALIE)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Coordination and support actions
Countries involved: Spain,France
Call: FET Innovation Launchpad (H2020-FETOPEN-2018-2019-2020-03, 2019)
Start date: 2020-09-01
End date: 2022-02-28
Duration (months): 18.0
Total project cost (EUR): 97750.0
EU funding (EUR): 97750.0
Participants: 2
Project status: CLOSED

NATHALIE project follows AMADEUS FET OPEN project which innovates in next generation materials and devices for latent heat thermal energy storage at ultra-high temperatures of up to 2000℃. NATHALIE will analyse possible new application sectors, their constraints and demands and potential market size and positioning. These findings will have a direct impact on designing next prototypes, eventually manufactured in subsequent R&D projects. Thus, NATHALIE findings will have valuable impact on the progressing velocity towards higher TRL. NATHALIE focuses on two possible markets for the AMADEUS technology: Commercial and institutional buildings and industrial process heat and power. It aslo plans to assess technology strengths and weaknesses and position into future and emerging energy value chains. The micro and macro external environmental analysis, consisting on PESTEL analysis, Porter 5 forces analysis and SWOT analysis will allow to better position developing technology towards future stakeholder expectations and will therefore allow defining technology specifications parameters to be adapted on each market segment. NATHALIE consortium involves UPM, former AMADEUS project coordinator and Ayming, specialist in market analysis.

Keywords: micro and macro external factors market analysis,energy storage,commercial and institutional buildings,industrial process heat and power,renewable fuel production plants
MOnItoRing of large scale complex technologicAl systems (MOIRA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Germany,Spain,Poland,Sweden,Belgium,Poland,France,France,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2021-03-01
End date: 2025-02-28
Duration (months): 48.0
Total project cost (EUR): 3958164.36
EU funding (EUR): 3958164.36
Participants: 12
Project status: SIGNED

Modern technological systems increase in scale and are becoming more and more complex and sophisticated. Parallel, the revolution in electronics, digital technology and communications have drastically modified and expanded the physical diversity, scope, processing capabilities and complexity of the monitoring equipment and infrastructure used. Millions of networked sensors are being embedded in the physical world sensing, creating and communicating data. The amount of data available for capturing has been exploding and the era of Big Data is already here, as the Internet of Things (IoT) is becoming a reality. The main question which arises is how, following which steps and with which tools the data can be transformed to information and knowledge. The objectives of MOIRA are i) the development of novel signal processing tools for the monitoring of industrial processes based on machine learning methods applied on heterogeneous time series, ii) the application of data mining technologies for the estimation of Key Performance Indicators which determine the operational profit, iii) the conception, development and validation of methodologies for automated monitoring of cyber physical system fleets, iv) the multi sensor machine condition monitoring under variable operating conditions. The proposed MOIRA project (MOnItoRing of large scale complex technologicAl systems) brings together early stage researchers and experienced specialists from key players in academia and industry across Europe covering different scientific disciplines and industrial stakeholders from a broad range of backgrounds to optimally tackle the challenges ahead. The MOIRA Fellows will be trained in innovative PhD topics as well as receiving specific theoretical and practical education in the fields of mechanical engineering and computer science, focusing towards the online early accurate identification of abnormal incidents with minimum false alarms and missed detections.

Keywords: condition monitoring,process monitoring,fleet monitoring,sensor fusion,fault detection,diagnosis,prognosis,vibrations
Imaging Receptomics as a tool for biomedical discovery (ReceptorPAINT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2022-04-01
End date: 2027-03-31
Duration (months): 60.0
Total project cost (EUR): 2348025.0
EU funding (EUR): 1598025.0
Participants: 2
Project status: SIGNED

Targeting cell surface proteins to alter cellular behavior is a major aim of many therapeutics. Recently approved immunotherapeutic drugs trigger anti-tumor immunity by disrupting key cell surface proteins that guide immune cell interactions. Despite the cell surface representing a major site of drug action, its nanoscale organization remains poorly characterized. The main reason for this is largely due to technical limitations of current fluorescence and super-resolution imaging approaches, which do not allow high-throughput measurements of the spatial localization and interaction of hundreds of proteins with true single-protein- resolution on cell surfaces. We here propose to develop exactly such a disruptive capability by advancing recently developed DNA-PAINT microscopy to enable the visualization and quantification of all relevant cell surface proteins at single-protein-resolution. We will achieve this by innovating DNA-PAINT to enable isotropic 1-nm-resolution, develop DNA-based protein binders against all cell surface proteins, and devise multiplexing capabilities to resolve them with single-protein-resolution over large fields of view, reaching the ultimate goal of enabling Imaging Receptomics. We will then apply this to test the central hypothesis that surface protein architecture and patterning on immune and tumor cells dictates the outcome of their interactions. We will map the nanoscale organization of hundreds of key immunomodulatory surface proteins and their corresponding ligands on key interacting pairs of immune cells relevant to current immunotherapy approaches (dendritic cells and T cells), as well as tumor cells. This will yield fundamental insights into the molecular architecture of their interactions and potentially enable the future development of more refined “pattern”-based immunotherapeutics. Collectively, this highly multidisciplinary and novel approach has the potential to be ground-breaking across a range of research fields.

Keywords: super resolution microscopy,dna nanotechnology,cell surface receptors,receptor tyrosine kinases,immune checkpoints