Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
ULTRA ACCURATE WORLD TIMING SERVICES II (WORLDTIMING II)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: SME instrument
Countries involved: Spain
Call: Engaging SMEs in space research and development (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-08-01
End date: 2019-01-31
Duration (months): 30.0
Total project cost (EUR): 1357137.5
EU funding (EUR): 949996.25
Participants: 1
Project status: CLOSED

The project aims at distributing ultra-accurate and traceable timing based on Galileo System Time (GST) through optical fibers. The goal is twofold. First, the project will facilitate the extension of the Galileo surface segment, through connecting the elements of the PTF and then the TVF. These links can be extended by using the telecom operators’ optical fiber infrastructure so that GSA and National Metrology Institutes can provide time as a service for key facilities all around the world. This allows deploying a terrestrial time network for the incoming 2020 applications, ultra-accurate, traceable with respect to UTC/Galileo GST and fully dependable. It will be a key solution to enable applications as autonomous navigation, UAVs, telecommunications infrastructure virtualization or indoor positioning. The second goal aims to provide a solution for Galileo GNSS receivers, resilient and secured against jamming and spoofing attacks. By distributing multiple GNSS receivers scattered around large areas we will provide a unique global clock reference, fully dependable for industrial applications. The target customers include critical infrastructures in segments like Telecommunications, Smart Grid and Finance (conventionally dependent on satellite signals) as well as next generation of Industrial Internet of Things and distributed systems. Our solution is possible with the emergent White Rabbit (WR) solution which is a sub-nanosecond accurate timing technology originally born at CERN for scientific facilities. WR is an extension of the standard Ethernet based on time distribution standards. As an extension of Ethernet, it can be easily integrated with existing communication networks at negligible bandwidth cost and can distribute time and frequency signals with 100 ps accuracy over long distances.

Keywords: gnss,galileo system time,precision time facility,time distribution,resilience,traceable time,critical infrastructures
Launching the Breakthrough in Lupus Diagnostics (ClarifyLupus)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Portugal
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-03-01
End date: 2019-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The difficulty on diagnosing lupus is due not only to the occurrence of overlapping symptoms with other autoimmune diseases but also to the unavailability of a lab test to confirm or rule out Lupus. The autoimmune disease is devastating, and the later it is diagnosed, the worse are the irreversible damages to the patients. In the USA alone, there are 13.8M people with Lupus and overlapping diseases and 2,6M new cases of these diseases are diagnosed each year. These diseases affect more than 25M people in the EU. We have developed a technology capable of identifying and quantifying altered proteins that play a key role in the onset of Lupus. Our product ClarifyLupus is a diagnostic test that is effective since the early stages of the disease. Although our competitors are conducting research on Lupus biomarker discovery, they all are focused in autoantibodies biomarker discovery that are highly unspecific among Lupus-confounding diseases. In contrast we have a Lupus-specific biomarker that enables the Lupus diagnosis much earlier than our competitors. We have passed the proof-of-concept stage where our diagnosis methodology was tested in blood samples and in January 2018 we have secured the Portuguese ethical committee approval to perform clinical assays, and are recruiting 50 patients until the end of the year. In April 2018 we secured a Letter of Support from the Egas Moniz Hospital in Lisbon, stating the importance and market disruption of ClarifyLupus. Clarify Analytical was founded in 2017 by Alexandra Antunes and João Rodrigues, two expert technologists in the fields of toxicology and mass spectroscopy, supported by 3 team members. The start-up was selected for the prestigious CoHiTech acceleration program in Portugal, focused on business and technology go-to-market. ClarifyLupus will be the breakthrough for Lupus diagnosis which will allow Lupus patients to be treated earlier, extending their lives by decades and improving their quality.

Keywords: lupus diagnostics,diagnostic tool,biomarker,lupus specific biomarker,mass spectrometry
Dust and gas in planet forming discs (DUSTBUSTERS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Australia,Germany,Italy,France,United States,United Kingdom,United Kingdom,Chile
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2018, 2018)
Start date: 2019-01-01
End date: 2024-09-30
Duration (months): 69.0
Total project cost (EUR): 639400.0
EU funding (EUR): 639400.0
Participants: 12
Project status: SIGNED

Planet formation is a widespread by-product of the process of star formation itself and occurs within relatively thin and dense protostellar discs made of gas and dust that orbit the newborn star. Such discs can now be probed with unprecedented detail thanks to high resolution telescopes and instruments, such as the Atacama Large Millimeter Array (ALMA) at sub-millimeter wavelegths or the SPHERE instrument at the Very large telescope (VLT) in the near infrared, which are both capable of probing nearby star formation regions with a spatial resolution of a few astronomical units. The overall aim of this project is to to strengthen the collaboration of groups located in Europe, USA, Chile and Australia - many of them already collaborating actively - in order to (1) develop and use suitable numerical algorithms and techniques to address key unsolved issues related to the interaction of newborn planets with the gas and dust environment in which they are born and (2) to compare such models with the most advanced observations of protostellar discs, obtained with high resolution telescopes in the IR and sub-mm.

Keywords: plant formation,accretion disks,protoplantary disks
REFUGEES IN THE GLOBAL ECONOMY: SITUATION, ROLE, AND IMPLICATIONS: THE CASE OF SYRIAN REFUGEE WORKERS IN THE EXPORT INDUSTRY IN ISTANBUL (FMGESI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-10-01
End date: 2022-12-15
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: CLOSED

This research aims to explore the situation of refugee-workers in the global economy and its implications for their everyday life. The forced migrant is usually seen as a person who receives aid rather than one who participates in economic production in the host country. Nevertheless, there are many studies which demonstrate the positive role of the refugees in the national economy of the host country. However, these usually focus on the role of the refugees entrepreneurs or other ‘elites’, thereby ignoring refugee-workers and their position in the global economy. As such, we could ask what role does refugee-workers play in the global economy? How does their position in this economy impact their everyday lives and thus their future plans? These are the orienting questions for the proposed research. The approach is as follows: First, we will conduct an analysis of the city and its borders. Second, an analysis of the workers’ situation. Finally we will explore in-depth the situation of refugee-workers by undertaking an explorative case study; Syrian refugee-workers in Istanbul. Here, we will use a qualitative approach with in-depth semi-structured interviews. We chose Istanbul because Turkey's economic policy makes it one of the biggest suppliers of textiles to Europe. It is also the country with the highest number of refugees in the world. Most of these are Syrian, and the biggest number of them reside in Istanbul. This research will make a great contribution toward two of the most relevant issues in the horizon 2018-2020 work program; societal resilience and market creation innovation. It will provide a better understanding and useful recommendations for policymakers on how to manage forced migration, with ‘sustainable development goals’ related to the integration of the refugees in their host society and economy. Furthermore, gender is at the heart of this view, since forced migration is usually accompanied by extreme changes in social roles, especially for women.

Keywords: forced migration,globalization,global economy,industrial relocation,gender
Peptide Killers of Bacteria (PeptideKillers)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Czechia
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2022-01-01
End date: 2026-12-31
Duration (months): 60.0
Total project cost (EUR): 2315705.0
EU funding (EUR): 2315705.0
Participants: 1
Project status: SIGNED

Antibiotic-resistant bacteria cause more than 700 000 deaths per year, and the forecast is 10 million per year in 2050. Moreover, emerging strains of bacteria resistant to all available antibiotics may lead to a global post-antibiotic era. Because of this threat, the WHO and the UN are encouraging the research and development of new treatments. The aim of this proposal is to design new peptides that selectively target and disrupt the membranes of pathogens but not those of human cells. To obtain such peptides, we will develop an innovative coarse-grained model of membranes and an original growth method, which will enable us to establish the relationship between peptide sequence motifs and their affinity to membranes with specific lipid compositions. Moreover, we will determine the critical peptide properties required for membrane disruption via the formation of transmembrane pores and spontaneous peptide translocation across membranes by devising new collective variables capturing these processes. Our computational advances will be complemented by experimental verification from peptide-membrane affinity measurements plus leakage and flip-flop fluorescence assays assessing membrane disruption. The most effective peptides will be evaluated for antimicrobial activity and human cell toxicity using growth inhibition and hemolytic assays, respectively. We will investigate mixtures of peptides for their synergistic increase in antimicrobial activity, and we will uncover the molecular mechanism of their synergism. The peptide behaviour will be quantified under equilibrium and more biologically relevant non-equilibrium conditions. The methods and knowledge obtained within this project will not only enable us to determine new peptides selectively killing bacteria, but will also enable the development of peptides targeted against membranes of enveloped viruses, cancer cells, or even cellular organelles with potential application as sensors, biomarkers, or therapeutics.

Keywords: computer simulations,phospholipid membrane,coarse grained model,lipid specificity,peptide,translocation,membrane pore formation,free energy calculation
Hard Probes of Hot and Dense QCD Matter (HPpQCD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2017-08-31
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

Several kinds of collision experiments such as the heavy ion programs conducted at the Relativistic Heavy Ion Collider (RHIC) and the Large Hadron Collider (LHC) give access to the study of QCD matter under extreme conditions. In particular, the creation of new states of matter as the deconfined quark-gluon plasma or the color glass condensate, where large densities of gluons can be found, present new opportunities to improve our overall understanding of strong interactions. It is proposed to use the several hard probes generated in these kind of setup (jets, heavy quarks, etc.) to study the properties of such states of matter through the implementation of perturbative techniques.

Keywords: heavy ion collisions,quark gluon plasma,jet quenching,small x
LEADING ULYSSEUS TO BECOME A EUROPEAN UNIVERSITY EXCELLENCE MODEL THROUGH RESEARCH AND INNOVATION (COMPASS)

Framework: Horizon 2020 — Science with and for Society
Action type: Coordination and support actions
Countries involved: Austria,Italy,Spain,Finland,Slovakia,France
Call: Support for the Research and Innovation Dimension of European Universities (Part II) (H2020-IBA-SwafS-Support-2-2020, 2020)
Start date: 2021-06-01
End date: 2024-05-31
Duration (months): 36.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 6
Project status: SIGNED

The Ulysseus European University is one of the 24 selected alliances from the second pilot call for proposals under the 2020 Erasmus+ work programme. The Alliance faces an ambitious 10 years endeavour that will contribute to shape the European Higher Education Area and the European Research Area , and hence the future of Europe. Ulysseus Alliance’s vision for 2030 is to develop an excellency-recognized and internationally attractive open to the world, persons-centred and entrepreneurial European University for the citizens of the future. The process of transformation towards this European University involves the generation of both a territorial and digital Innovation Ecosystem, the Ulysseus Innovation Ecosystem. Understanding our Alliance as one Innovation Ecosystem developing solutions for specific R&I challenges from Innovation Hubs, is Ulysseus unique and distinguishing feature. The Ulysseus Ecosystem rests on two solid foundations: the Ulysseus Community , representing the helix and including the 6 Alliance partners and 95 associated partners ; and the Ulysseus Campus. COMPASS is the flagship for Ulysseus R&I agenda, so its aim is to build upon this vision by establishing Ulysseus as a model of excellence for research and innovation transformation in line with the shared, integrated, long-term joint strategy of the alliance, boosting synergies between the European Research Area and the European Education Area. COMPASS will support the development of strategies and concrete action plans in order to position Ulysseus as an institutional transformation model at research and innovation level. Through COMPASS, the alliance will reinforce their joint long-term vision for research and innovation to drive systemic, structural and sustainable impact at all levels of the institutions involved.

Keywords: european universities,innovation ecosystem,randi strategy,era hubs
Speciation and bioavailability of heavy metal cadmium (Cd) in the soil-plant system: a novel approach combining stable isotope geochemistry and experimental spectroscopy. (SPECADIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-02-04
End date: 2021-02-03
Duration (months): 24.0
Total project cost (EUR): 185076.0
EU funding (EUR): 185076.0
Participants: 1
Project status: CLOSED

The environmental pollution by ecotoxic heavy metals is an issue of increasing significance for ecological and human health reasons. Among these elements, cadmium (Cd) is of special concern due to its high mobility in the soil/plant system and its acute toxicity towards most forms of life, which requires monitoring of food products, especially crops. Improving food security represents a major European priority and is one of the societal challenges targeted by Horizon 2020. In this context, SPECADIS overarching objective is to enhance our understanding of Cd bioavailability to crops and bring constraints on the mechanisms that govern the uptake and fate of Cd in the plants that feed the world. Previous studies have demonstrated that Cd bioavailability in the plant/soil system depends ultimately on its chemical speciation, for which in situ determination remained out-of-reach until now. To investigate Cd speciation in crops, SPECADIS will use a novel multidisciplinary framework combining the most recent advances of two cutting-edge technologies: X-Ray absorption spectroscopy and stable isotope mass spectrometry. SPECADIS will (i) use the newly developed High Energy Resolution Fluorescence Detected X-ray Absorption Spectroscopy technique to bring, for the first time, in situ Cd speciation measurements in crops and (ii), combined with Cd isotope geochemistry, unravel the relationships between Cd isotope fractionation and Cd speciation changes in crops to develop a tracer of Cd speciation in dilute samples. SPECADIS will be hosted by the environmental geosciences AMU department CEREGE. The fellow will bring her expertise in heavy metal isotope geochemistry to a team of internationally renowned spectroscopists and soil scientists, who will train her and encourage her to develop her leadership skills. SPECADIS results will be disseminated to the range of specialist and non-specialist audiences, enhancing the visibility of its innovative approach on an international scale.

Keywords: heavy metal pollution,cadmium,cd biogeochemical cycle,toxicity,bioavailability,soil,plant system,cd isotopes,cd speciation,xas spectroscopy,stable isotope geochemistry,crops contamination
A novel wearable, cost-effective and non-invasive biometric body worn video solution for accurate and high throughput screening of people, bags and vehicles (BIO-AX)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: United Kingdom
Call: Critical infrastructure protection topic 7: SME instrument topic: Protection of Urban soft targets and critical infrastructures (H2020-SMEINST-2-2015, 2015)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 1170284.25
EU funding (EUR): 772282.88
Participants: 1
Project status: CLOSED

AUDAX Global Solutions Ltd. is an SME founded in Plymouth UK in 2005. Since then it has become a pioneer in the delivery and development of mobile digital evidence gathering products and services. The AUDAX team consists of the most knowledgeable experts in the industry who are committed to offer groundbreaking innovative solutions. AUDAX owns a new technology Bio-AX™, a unique, wearable and non-intrusive biometric body worn video system that can screen people, bags with high throughput and high accuracy. This technology will bring many benefits to the stakeholders and increase security in our communities. AUDAX sees a huge business opportunity through sales. The uniqueness of Bio-AX™ will increase the Unique Selling Proposition (USP) of our products and competitive advantage in the market. AUDAX have passed Feasibility Study and Customer Development, and believe that Bio-AX™ will raise the Company’s profitability and grow its workforce. The project is feasible, viable, profitable and sustainable. AUDAX is seeking financing through SME Instrument to fund the transition of the TRL6 prototype into commercialisation.

Keywords: biometric body worn video
Smartphone-based monitoring of jaundice in newborns (Picterus)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Norway
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2019)
Start date: 2020-03-01
End date: 2022-08-31
Duration (months): 30.0
Total project cost (EUR): 2382005.0
EU funding (EUR): 1663903.5
Participants: 1
Project status: CLOSED

Worldwide, 114.000 newborns die each year due to neonatal jaundice, a common condition caused by high levels of bilirubin. Approximately the same number of children grow up with permanent disabilities associated with brain damage when jaundice is not diagnosed early and treated. Current solutions for jaundice diagnosis require hospital laboratory facilities for blood testing and newborn monitoring by professional healthcare workers. Estimations indicate that jaundice management increases healthcare costs by €1684 million every year. In answer, Picterus have developed innovative technology based on biomedical optics and photonics complemented with machine learning algorithms that facilitate accurate remote diagnosis of jaundice by taking a simple picture with a Smartphone. Unlike the current solutions used for jaundice diagnosis, Picterus enables health personnel and parents to screen new-borns for jaundice with a tool that is reliable and comes at a low cost, regardless of the geographical location. By using Picterus, midwives or nurses doing early home-visits can safely assess the degree of jaundice in the new-born and save time that can be allocated to other needs the new-born or family might have. It reduces the need for hospital visits, and further, it reduces stress on the midwives and parents. The reduction in healthcare costs, due to remote and low-cost diagnosis of neonatal jaundice, will allow better allocation of resources in other important medical areas, but our contribution to solving the problems associated with jaundice in low- and middle-income countries (where current tools are often too expensive for a routine use) will produce a more significant impact. Picterus has the capacity to reduce outpatient visits for jaundice by 50%, with potential savings of €306 million. Through commercialisation of this innovation, we have projected that our global turnover will reach €25 million and create a total of 14 direct jobs by the 4th year of introduction

Keywords: jaundice,kernicterus,biomedical optics,photonics,machine learning,image based diagnostics,calibration card,algorithmic analysis,paediatrics,sensitivity