Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Precise and secUre autoMotive trAcking (PUMA)

Framework: FP7 — Cooperation
Programme: Transport (including Aeronautics)
Destination: Support to the European global satellite navigation system (Galileo) and EGNOS
Action type: Collaborative project
Countries involved: Germany,Italy,Poland
Call:  (FP7-GALILEO-2008-GSA-1, 2008)
Start date: 2009-12-15
End date: 2011-10-14
Duration (months): 18.0
Total project cost (EUR): 358545.0
EU funding (EUR): 289802.0
Participants: 3
Project status: CLOSED

The PUMA project aims to develop a solution to mitigate the increasing problem of GNSS jamming and spoofing in road applications. With GPS jammers increasingly available in specialized electronic stores and on the Internet for less than 50€, this risk of disruption for safety and financially critical road applications such as road tolls, PAYG insurance, anti-theft systems or hazmat tracking is ever increasing. The PUMA consortium, composed by partners with expertise in automotive, GNSS security and inertial sensors, aims to build a GNSS/EGNOS GSM tracking module that can interpret the wheel speed data from the car diagnostic system (available by default in all recent cars) and translate it to data compatible with a standard GNSS/EGNOS dead-reckoning (DR) ready receiver. This will allow seamless integration of DR tracking devices simply connecting the device to the standard OBD-II connector available in all vehicles, avoiding the use of inertial sensors. Furthermore, research will be conducted to support the implementation of anti-spoofing algorithms based on the comparison of DR trajectories and GNSS observables. Such anti-spoofing techniques represent a high level of innovation, facilitating effective spoofing mitigation for low-cost mass-market road applications without the need for cryptographic signal authentication. We foresee an enormous market potential for this technology as it resolves numerous issues that are obstacles to the adoption of Galileo and EGNOS in the road sector.

Keywords: gnss tracking,jamming,spoofing,dead reckoning,gnss integrity,gnss secuirty,egnos,galileo,gps,wheel speed
Generalising Robot Manipulation Task (GERT)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Cognitive systems, interaction, robotics
Action type: Collaborative project
Countries involved: Germany,United Kingdom,Sweden,Germany,Germany
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-03-01
End date: 2013-02-28
Duration (months): 36.0
Total project cost (EUR): 3691311.0
EU funding (EUR): 2822797.0
Participants: 5
Project status: CLOSED

In order to work naturally in human environments robots of the future will need to be much more flexible and robust in the face of novelty than those of today. In GeRT we will develop new methods to cope with novelty in manipulation tasks. Humans cope seamlessly with novel objects: we do not think of grasping a new cup, or screwing the lid off a jar we haven't seen before as challenging. This kind of everyday novelty is hard for a robot. The most advanced robots can perform a task such as making a drink, which involves grasping, pouring and twisting off a cap from a jar. But the rules must be precisely programmed. The ability to manipulate fifty different objects means writing fifty different programs. When the robot encounters an object it hasn't seen before, it can't grasp the object. If one object in a task changes then the program for the whole task may need to be rewritten. If we substitute a mug for a glass in a task that involved pouring liquid from the mug or glass into another object, the pouring position changes, as changes the grasping position. Perhaps we would grasp the mug by the handle, and then tip it sideways to pour. All of this means that if robots are ever going to be useful in natural settings where manipulation is involved that they need ways of generalising on the fly to cope with novel objects, and perhaps novel tasks. Our approach is to take a small set of existing robot programs, for a certain robot manipulation task, such as serving a drink and to give the robot the ability to adapt them to a novel version of the task. These programs constitute a database of prototypes representing that class of task. When confronted with a novel instance of the same task the robot needs establishing correspondences between objects and actions in the prototypes and their counterparts in the novel scenario. To achieve that, GeRT will use a variety of techniques from machine perception, machine learning and Artificial Intelligence such as automated planning.

Keywords: hybrid planning,task generalisation,grasp optimisation,perception
Cellular Mechanisms and Therapies for Rett Syndrome (NEUROTHERAPY)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ireland
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-07-01
End date: 2012-06-30
Duration (months): 24.0
Total project cost (EUR): 50000.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Rett Syndrome (RTT) is an X-linked neurodevelopmental disorder and the leading known genetic cause of autism in girls. RTT is characterized by normal early development followed by cognitive, motor and language regression. Mutations in the X-linked MECP2 (methyl-CpG binding protein 2) gene account for at least 80% of RTT cases. In mouse models, CNS-specific deletion of Mecp2 is sufficient to cause Rett-like symptoms. In patients as well as in the mouse models, the involved CNS circuits do not show atrophy but rather remain in an immature state. Although there is no known cure for RTT, gene therapy in MeCP2 mutant mouse models has proven effective in rescuing the phenotype, showing that this neurological condition may be reversible. A therapy for human use might arise from identifying an agent capable of stimulating brain circuit maturation if applied systemically. This proposal identifies such an agent in the form of insulin-like growth factor 1 (IGF1), a pleiotrophic growth factor in the brain. IGF1 specifically targets many of the systems and features impaired in RTT such as cell size and dendritic arborization, synapse maturation, the gabaergic system, hippocampal learning and plasticity, and cognitive abilities. IGF1 is capable of crossing the blood-brain barrier and has already been approved for human clinical trials. IGF1 thus offers a means to reverse the RTT phenotype by engaging key molecular pathways to stimulate synaptic maturation, in a format that is more amenable to therapeutic administration to RTT patients. This proposal aims to clarify the neurobiology of MeCP2 protein in MECP2 mutant animal models and to test the efficacy of IGF1 and its derivates for RTT therapy. Successful therapies for RTT have significant implications for other autism spectrum and neurodevelopmental disorders.

Keywords: health sciences,rett syndrome,insulin-like growth factor 1
Translational study on the antigen presenting properties of human vs mouse B cell subpopulations (BCELLSMICETOMEN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Bulgaria
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-04-15
End date: 2013-04-14
Duration (months): 36.0
Total project cost (EUR): 75000.0
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Our recent results on antitumor effects of carbohydrate mimotope peptides (CMP) suggest a possible role of carbohydrate reactive B cell subpopulations as cellular adjuvants. As an abundant alternative of dendritic cells, CD40-activated B cells can efficiently present specific antigens being expandable for several weeks. Some B cells can be sufficiently detrimental to warrant anti-B cell therapy in cancer. Other (mouse) B cell subsets (e.g. B1 and marginal zone (MZ) B cells) seem as effective as mature DC, including skewing the T cell to the desirable Th1 responses. Thus, B subpopulations deserve scrutiny as the optimal antigen presenting cells. We hypothesize that CMP target carbohydrate reactive B cells, which present the collinear T cell epitopes to auxiliary T cells, create an environment conducive to epitope spreading to glycoprotein tumor antigens. The major mature B cell subpopualtions in the mouse are B2 follicular cells, MZ B cells, as well as B1a and B1b peritoneal B cells. The translation of a B cell strategy to the clinic is hindered by lack of straightforward functional homologies between mouse and human B cell subsets. Therefore, we propose to study the potential of ex vivo expanded human B cell subpopulations to present CMP and induce an appropriate cytokine environment for the development of anti-tumor CTL responses in comparison to the mouse system. To this end we propose to compare the phenotype and antigen presenting properties of mouse and human CMP specific B cells. These studies will allow for the design of therapeutic approaches based on ex vivo expansion of phenotypically similar B cells and using them for active immunotherapy of cancer after loading with appropriate antigens. The relevance of the CMP specific system to a bulk population of the same phenotype stems from the capacity of B cells to present antigens targeted nonspecifically for instance to CD19.

Keywords: immunology,b lymphocyte,marginal zone,b1 b cells,t lymphocyte,subpopulations,antigen presentation,carbohydrate,vaccine,mouse,human,cytokine,mimotope
Pattern REcognition-based Statistically Enhanced MT (PRESEMT)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Cognitive systems, interaction, robotics
Action type: Collaborative project
Countries involved: Greece,Norway,Czechia,Germany,United Kingdom
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 3275493.0
EU funding (EUR): 2500000.0
Participants: 6
Project status: CLOSED

This proposal describes PRESEMT, a flexible and adaptable MT system, based on a language-independent method, whose principles ensure easy portability to new language pairs. This method attempts to overcome well-known problems of other MT approaches, e.g. bilingual corpora compilation or creation of new rules per language pair. PRESEMT will address the issue of effectively managing multilingual content and is expected to suggest a language-independent machine-learning-based methodology. The key aspects of PRESEMT involve syntactic phrase-based modelling, pattern recognition approaches (such as extended clustering or neural networks) or game theory techniques towards the development of a language-independent analysis, evolutionary algorithms for system optimisation. It is intended to be of a hybrid nature, combining linguistic processing with the positive aspects of corpus-driven approaches, such as SMT and EBMT. In order for PRESEMT to be easily amenable to new language pairs, relatively inexpensive, readily available language resources as well as bilingual lexica will be used. The translation context will be modelled on phrases, as they have been proven to improve the translation quality. Phrases will be produced via a semi-automatic and language-independent process of morphological and syntactic analysis, removing the need of compatible NLP tools per language pair. Parallelisation of the main translation processes will be investigated in order to reach a fast, high-quality translation system. Furthermore, the optimisation and personalisation of the system parameters via automated processes (such as GAs or swarm intelligence) will be studied. To allow for user adaptability, all the corpora used in PRESEMT will be retrieved from web-based sources via the system platform, while the user feedback will be integrated through the use of appropriate interactive interfaces. PRESEMT is expected to be easily customisable to both new language pairs and specific sublanguages.

Keywords: machine translation,pattern recognition,smt,language-independen method,syntactic phrase-based modelling,evolutionary algorithms
Hepatitis C virus virion-bound proteins: identification in clinical samples and in vitro dissection of their importance in the viral life cycle (HCV-BOUND PROTEINS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-07-01
End date: 2014-06-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The emergence of hepatocellular carcinoma (HCC) has prompted a search for a thorough understanding of the biology of one of its major causative agents, the hepatitis C virus (HCV). Half of genotype 1 patients, the most numerous in Europe, do not respond to treatment, putting them at risk for cirrhosis and HCC. HCV particles acquire via budding and encapsidation cellular proteins. There is mounting evidence on several viral species that virion-bound proteins are prone to be involved either at the replication, budding/egress or entry/release steps of the viral cycle. Identifying such targets may yield ideal candidates for gaining insight on the dependence of HCV upon a restricted subset of host proteins, therefore providing refined sets of genetically stable targets for therapy. This project’s goals are to set up adequate conditions for robust and reproducible purification of HCV virions in clinical samples, followed by the identification of their HCV-bound host proteins and the characterization of their functions. Proteomics profiling of HCV particles purified from clinical samples will be overlaid with proteins identified and characterized in cell culture-grown HCV particles during my post-doctoral training, using clinical biomarker discovery grade criteria. Targets identified in both samples sets will be subjected to in vitro investigations using HCV-replicating cells. Conventional biochemical and imaging methods will be used in order to: (i) ascertain their physical association with HCV virions; (ii) define the modalities of their interaction with HCV proteins; (iii) decipher the topology and subcellular localization of their association with HCV proteins and virions; (iv) quantitatively assess their functional involvement in particle budding, egress or secretion and infectivity. A candidate that yielded satisfactory results in these experiments will be disclosed and further investigated at the level of structural biology, in collaborative research programs.

Keywords: health sciences,virology,hepatitis c virus,hcv-bound host proteins,clinical samples,proteomics,biochemistry,cell biology
Trusted computing Engineering for Resource constrained Embedded Systems Application (TERESA)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: France,France,Germany,Germany,Germany,Spain
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2009-11-01
End date: 2013-01-31
Duration (months): 39.0
Total project cost (EUR): 3788733.0
EU funding (EUR): 2899994.0
Participants: 6
Project status: CLOSED

The objective of TERESA is to define, demonstrate and validate an engineering discipline for trust that is adapted to resource constrained embedded systems. We define trust as the degree with which security and dependability requirements are met. Resource constrained embedded systems are characterized as follows: • They belong to different application sectors • Computing resource are mostly statically determined and allocated through a process consisting of a configuration phase and a build phase • They are generally high integrity systems with strong assurance requirements. They therefore use advanced engineering disciplines. The proposed approach is to use a model-based repository of security and dependability patterns: • Application sector trust models are defined as profiles (e.g. UML, SysML profiles), based on a common trust meta-model • Security and dependability patterns, platform independent are identified and defined for each application sectors (some patterns could be used by several application sectors) • Formal properties on security and dependability are defined and validated for patterns used in application sectors requiring this level of assurance • Platform dependent implementation of the patterns are of the patterns are guided with very precise requirements The engineering process for resource constrained embedded systems will be validated in four application sectors: automotive systems, home control systems, industry control, and metering.

Keywords: engineering,resource constrained embedded systems,models,patterns,trust,security,dependability
Interoperability of connected Personal Health Systems (PHS) with the wider eHealth domain – Promoting the smart delivery of health services (SMARTPERSONALHEALTH)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Towards sustainable and personalised healthcare
Action type: Coordination and support actions
Countries involved: Belgium,France,Germany
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2011-01-31
Duration (months): 13.0
Total project cost (EUR): 426963.0
EU funding (EUR): 399364.0
Participants: 6
Project status: CLOSED

The overall benefits of eHealth can only be realised if stakeholders comprehend and support interoperability of eHealth infrastructures and applications, as outlined in the recent EC Com-munication on Cross-border Interoperability of Electronic Health Records. This Support Action will promote interoperability (IOp) among Personal Health Systems (PHS) and between eHealth systems – in the landscape of continuous care, across multilingual and multi-cultural environments in Europe. A promotion concept and events plan will be developed in the context of a structured, evidence-based discussion framework on IOp. Key activities will include three thematically focused regional stakeholder workshops, one central pan-European PHS Interoperability Conference, and further promotion, networking &amp; dialogue via modalities such as the Continua Health Alliance web portal, and other promotional material. Relevant stakeholder groups as well as related EU, national and industrial IOp initiatives and projects will be involved. Finally, a concise report on key outcomes from all promotional activities and stakeholder dialogues will be compiled, highlighting the current status, concerns, barriers and incentives to accelerate the development and adoption of interoperable PHS systems. Further recommendations for IOp promotion will be proposed to the EC, national governments, stakeholder groups and industry. Partners are The Centre, a European expert in public affairs/ organising events, Continua, the global industry consortium to promote the interoperability of PHS devices and systems, ETSI, the European Telecommunications Standards Institute, responsible for standardization of ICT within Europe, and IHE, worldwide reference organisation for the interoperability of clinical information systems. The project lasts 12 months, and budgets € 399,000. Members of Continua, ETSI and IHE are expected to contribute at least another 14 person months “in kind”, estimated to be worth ca. € 150,000.

Keywords: interoperability,personal health systems,ehealth,continuous care,chronic disease management,independent ageing
Complex dynamics in higher dimensions: Fatou Theory. (COMPLEX DYNAMICS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-01-01
End date: 2013-12-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Dynamical systems occur as models in all the physical sciences. One dimensional dynamical systems have been studied to great depth but their use as models is limited. Higher dimensional systems have recently received great attention but they tend to be much more complicated. We propose to study complex dynamical systems in dimensions two and higher. The main emphasis is on the set where the dynamical behavior is orderly, called the Fatou set. In one complex dimension the Fatou set is completely understood but in higher dimensions many important problems are completely open. The reintegration grant will enable us to create an excellent research environment for complex dynamical systems in Amsterdam. Funds from the grant will be used to support the research of the applicant, set up a complex dynamics seminar at the University of Amsterdam, invite guests to Amsterdam and organise a workshop in several complex variables. The grant will also allow the applicant to spend one semester in the United States where he will solidify his connections with strong complex dynamics groups at SUNY Stony Brook and the University of Michigan.

Keywords: complex analysis,discrete dynamical systems.
Investigating Battery and Capacitor Sizing Problems with More Efficient Power Flow Control Techniques for Sustainable Hybrid Electric Vehicle Development (SUSTAINABLE HYBRID)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Türkiye
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-06-01
End date: 2014-05-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Hybrid Electric Vehicles with two electric motors, each supplied by its own dedicated inverter becomes more popular due to its fuel economy benefit and satisfactory drivability. This project aims to investigate new methods for power flow control to apply to this system so that battery and DC link electrolytic capacitor current ripple at low and high frequencies can be reduced. Lower ripple in current will eventually result in benefits in battery and capacitor. These benefits can be listed as smaller size, better thermal performance, cost and packaging. As a first step, permanent magnet synchronous motor and induction motor will be simulated to investigate control angle versus dc link current ripple relation as well as inverter switching scheme and dc link current ripple relation. Once these relations are analyzed, new control angle variation schemes and inverter switching schemes will be developed to reduce current ripple in the dc link. The system under consideration is a two-motor drive system and duty cycles of two motors are different since the duty cycles are imposed by drive cycle requirements. This suggests that the motors may not be in use with their full capability. Unused part of their current and power capability, then, can be used to control dc link current ripple. In order to be more systematic during analysis, Instantaneous Power Theory will be used. This theory would allow us to see low frequency and high frequency active and reactive power flow in the system. Investigation will be done to see the relation between ripple in power and ripple in dc link current. Low frequency ripple will be suppressed by careful adjustment of control angles in each motor whereas high frequency ripple will be suppressed by playing with the switching schemes of two inverters.

Keywords: hybrid electric vehicle,electric machinery,power electronics,battery sizing,current ripple