Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
SENTAB: Combatting Senior Loneliness through Fun and Entertaining Technology (Sentab)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Estonia
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-2-2014, 2014)
Start date: 2015-04-01
End date: 2017-06-30
Duration (months): 27.0
Total project cost (EUR): 2340000.0
EU funding (EUR): 1638000.0
Participants: 1
Project status: CLOSED

A recent study by the researchers of USCF concluded that 43% of seniors over 60 years old feel lonely. The same study concluded that isolated elders had 59% higher risk of physical and mental decline, and 45% see greater risk of death. There are 162 million senior citizens in Europe, and the problem of loneliness affects nearly 65 million Europeans. These people and their families are the target group for Sentab products with the estimated sales potential in Europe alone in excess of €500M per year. Sentab system is a platform providing entertainment, social interaction, and monitoring functions connecting seniors, their caregivers and relatives seamlessly over the interfaces that are the most common for them – TV interface for seniors, and web and mobile interface for caregivers. Early trials at 5 nursing homes in the Greater London Area, UK, indicate that Sentab features have a good alignment with seniors’ and caregivers’ needs, but equally, it is necessary to augment the system with further data analysis capabilities to determine emotional state, and short and long term memory conditions of seniors. The project will also establish a solid go-to-market activities mix that will encompass B2B engagements with Nursing and Assisted Living Homes (TAM globally €2Bn), followed subsequently by penetrating B2C Independent Living marketplace (TAM €100Bn). Ability to analyse user behaviour data on a cost efficient platform and soliciting early actions to respond on negative changes makes this system unique and powerful in changing the habits of elderly care. With this project, Sentab will develop set of complex software algorithms for detecting mood patterns and recognizing trends in senior’s emotional state, an internet protocol based communications system and a data base management system. This innovative product will be then placed on EU Assisted Living market.

Keywords: infortainment and monitoring system for elderly,user behaviour analysis,social interaction
Nanomaterial surface interactions at the molecular level and their impact on ecotoxicity (MolNANOtox)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-05
End date: 2018-03-18
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 2
Project status: CLOSED

As nanotechnology continues to advance at an exponential rate, new products are continuously introduced into the market for research and consumer use. Engineered nanomaterials (ENMs), the functional components in these products, are often specifically designed to exploit the unique properties that nanomaterials exhibit; however, there is a widespread uncertainty on how these new properties may also potentially translate into novel risk issues in the environment. In particular, their high specific surface area and surface reactivity may promote distinct interactions with organisms particularly at the lower trophic levels. This can depend on both the intrinsic and extrinsic properties of ENMs, and can be affected by the formation of an “eco-corona”, which is composed of environmentally derived macromolecules from the milieu in which the ENMs are exposed that adsorb to the ENMs surface. However, understanding these interactions at the molecular level and their mechanistic consequences are severely limited and technically challenging, requiring a cross discipline approach. This project aims to address this knowledge gap by uncovering the underlying mechanisms for the formation and persistence of eco-coronas on a range of ENMs by combining fundamental ENM chemistry, environmental toxicology, advanced optical and mass spectroscopy and imaging techniques. In particular, this project will apply surface enhanced spectroscopic methods to characterise eco-corona composition and evolution and how this affects ENM interactions with, and impact upon unicellular organisms. By correlating the eco-corona composition with uptake route (or accumulation at external membrane) and toxicity response, and by investigating how these ENMs are partitioned within model species, the project proposes to identify the molecular basis that determines the fate and toxicology of ENMs in the environment.

Keywords: nanotoxicology,ecotoxicology
Novel 3D platforms to engineer bone microtissues for in vitro disease models (MicroBone)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Portugal
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2018-03-01
End date: 2019-08-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Osteosarcoma is a rare but devastating bone tumour that mainly affects children, adolescents and elderly. This type of tumour is very resistant to therapy, being thus urgent to find new effective treatments. In vitro tumour models can recapitulate many aspects of the natural tumour environment, and could be used to improve the predictive value of the effect of anticancer drug candidates. The aim of MicroBone is the development of biological relevant spherical-based 3D disease models that could be used as an enabling tool for personalized and precision drug discovery, increasing our understanding of the mechanisms behind bone cancer and testing new drug-based therapies.

Keywords: disease models,hydrogels,encapsulation technology,cancer,business plan
Terrestrialization: Stress Signalling Dynamics in the Algal Progenitors of Land Plants (TerreStriAL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Germany
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2019-11-01
End date: 2025-04-30
Duration (months): 66.0
Total project cost (EUR): 1494226.0
EU funding (EUR): 1494226.0
Participants: 1
Project status: SIGNED

Land plants abound on Earth’s surface. All of this diversity arose in a singular event. The algal progenitor of land plants was a streptophyte alga and only recent phylogenomic analyses have specified the particular algal lineage that is most closely related to land plants. But why did land plants evolve only once? And what properties did the ancestors of these terrestrial organisms possess that allowed them to conquer land? Life on land involves rapid and drastic shifts in temperature, light or water availability. Hence, a prime candidate property is the ability to deal with these terrestrial stressors by dynamically responding to shifting environmental cues. My recent data highlight that the streptophyte algae closest to land plants have the genetic makeup for land plant-like stress response signalling circuits—including genes for sensing the major stress phytohormone abscisic acid (ABA). This provides us with testable candidates. To shed light on the early evolution of one of land plants’ key properties, I, here, propose to combine in-depth molecular biological analyses of these candidate stress signalling and response pathways with large-scale systems biology approaches. For this, my team and I will develop streptophyte algal model systems. We will dissect the regulatory hierarchy employed during stress signalling and the response pathways it is regulating in real-time in vivo and across evolutionary time in silico. These approaches will go beyond a view of gene evolution that is based on presence/absence to address if land plant stress dynamics have evolved from algal stress regulatory networks that became hardwired into land plant biology. The aim of this work is to infer the biology of the earliest land plants by investigating their closest algal relatives and interrogating a candidate mechanism used to deal with the challenges of life on land. Understanding this mechanism means understanding a key player that paved the way for the success of plants on land.

Keywords: plant terrestrialization,early plant evolution,streptophyte algae,plant physiology,evo physio,gene regulatory networks
Neural Active Visual Prosthetics for Restoring Function (NeuraViPeR)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Sweden,Belgium,Switzerland,Netherlands,Netherlands
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2019)
Start date: 2020-09-01
End date: 2025-02-28
Duration (months): 54.0
Total project cost (EUR): 3998681.25
EU funding (EUR): 3998681.25
Participants: 8
Project status: SIGNED

Approaches that aim to restore vision for blind individuals with electrical stimulation of the brain have hit a technology wall. Existing systems only stimulate a small set of neurons in the brain, and interfaces have a longevity of only a few months. NeuraViPeR aims to lay ground-breaking foundation for a radically new paradigm which consists not only of constructing a neuroprosthesis with thousands of electrodes but also the creation of adaptive machine learning algorithms for a new brain-computer interfacing technology, which will remain safe and effective for decades. Several technological breakthroughs will be established. First, innovative approaches for stimulation with high-electrode-count interfacing with the visual cortex; creating thin (~10 µm thick, < 50 µm wide) flexible probes that cause minimal tissue damage; new electrode coatings that will be stable in spite of long-term repeated electrical stimulation; and novel microchip methods for combining online channeling of the stimulation currents to many thousands of electrodes, combined with monitoring of neuronal activity in higher cortical areas. Second, new deep learning algorithms that transform the camera footage into stimulation patterns for the cortex and that use feedback on recorded brain states and eye tracking to improve perception in a closed-loop approach. The algorithms will extract maximally relevant information to enable blind individuals to recognize objects and facial expressions and navigate through unfamiliar environments. The software algorithms will be translated onto low-latency, power-efficient neuromorphic deep learning hardware, to create a neuroprosthesis system that is lightweight, robust, and portable. NeuraViPeR will tackle these challenges through interdisciplinary teams with complementary expertise in computational, systems and clinical neuroscience, materials engineering, microsystems design, and deep learning.
Ancillary Services from Smart Thermostatic Loads in Power Grids (SmarTher Grid)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Cyprus
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 157941.12
EU funding (EUR): 157941.12
Participants: 1
Project status: CLOSED

The penetration of renewable sources of energy in power networks is expected to grow over the next years, motivated by environmental concerns. However, renewable generation is in general intermittent and a large penetration may cause frequent generation-demand imbalances that may compromise power quality and even result in blackouts. Demand side participation can offer a solution to this problem, due to loads ability to provide a fast response when required. However, a large portion of the total demand corresponds to thermostatic loads (TLs), which are characterized by a cyclic thermostatic behavior. Such effects need to be taken into account in the design of control schemes for TLs, if those are to provide support to the power grid. The primary technical research objective of this project is the design of control schemes for TLs such those provide effective, efficient and reliable ancillary support to the power network. In particular, the major research objectives of the project are to: (a) Enable TLs to provide ancillary support to existing frequency control mechanisms, ensuring that those switch when there is an urgency. (b) Obtain an optimal power allocation between TLs with minimum user disruption. (c) Provide analytic stability guarantees for power networks when the proposed TL control designs are implemented. (d) Enable further research on TLs, by providing analytic models that characterize their aggregate behavior. (e) Validate the proposed control designs with realistic numerical and hardware in the loop simulations. The main career objectives are to: (a) Strengthen the research skills of the fellow with training on advanced simulation tools, power systems analysis and control theory. (b) Enable the transfer of knowledge between the fellow, the scientific community and the industry. (c) Enrich the transferable skills of the researcher with training on presenting to wide audiences, writing research grant proposals and managing intellectual property.

Keywords: smart grids,demand side management,frequency control
European Centre for Risk Management and Safe Innovation in Nanomaterials Nanotechnologies (EC4SafeNano)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Ensuring the safe and sustainable development and application of nanotechnologies
Action type: Coordination and support actions
Countries involved: Austria,Germany,Spain,Italy,Germany,Belgium,Belgium,Finland,Greece,Sweden,France,France,Netherlands,United Kingdom,Denmark,United Kingdom
Call: Promoting safe innovation through global consolidation and networking of nanosafety centres and strengthening the European industry through cooperation in nanosafety (H2020-NMBP-CSA-2016, 2016)
Start date: 2016-11-01
End date: 2019-10-31
Duration (months): 36.0
Total project cost (EUR): 1999013.75
EU funding (EUR): 1999013.25
Participants: 16
Project status: CLOSED

A significant challenge to ensuring sustainable production and use of nanotechnologies is to understand safety and health risks of the technology and its end-products, and to implement practical strategies to manage these risks. Knowledge is growing rapidly, but effective use of this knowledge for risk management is lagging behind. We therefore need to bridge the gap between knowledge on hazard and risk, and ‘fit-for-purpose’ risk management tools and strategies supported by measurement and control methods. EC4SafeNano will bridge this gap in an efficient and sustainable way by setting up an independent, science-based, managed Centre (hub) linked with several networks (spokes) to act at the interface between research organisations, industry, regulatory bodies, and civil society. The objectives are to: 1) understand the needs of all stakeholders along the innovation value chain for nanotechnologies, ensuring safer, marketable, regulated and accepted long-lived products; 2) identify the resources and capabilities available to address these needs, and evaluate the capacity to provide technical solutions and actions; 3) build, test and benchmark a range of services, based on selected resources that answer stakeholder needs across the innovation value chain; 4) develop mechanisms and operating procedures to facilitate periodic updating of the “needs and resources” mapping and of the service provision; 5) develop networking activities aiming to share, benchmark and promote the EC4SafeNano services thereby enhancing and harmonizing the overall expertise, at EU level and beyond; and 6) develop governance rules and a strategic plan to prepare for self-sufficient operation beyond the project lifetime. The main outcome is the definition of a legal entity with operating procedures, gathering, integrating and sharing available technology, tools, skills and processes and promoting services and capabilities to support stakeholder needs in risk management and safe innovation.
Towards a Digital Critical Edition of The Works of Giuseppe Verdi (DiCrEd)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-01
End date: 2021-06-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Critical editions of 19th-century Italian opera have been appearing in print for over four decades, offering the basis for productions in major European theatres, as well as for audio and video recording with world leading singers, which continue to engage millions of people today. Established in 1983, _The Works of Giuseppe Verdi_ (University of Chicago Press and Ricordi) aims to publish all of Verdi’s music in a critical edition, relying on the rigorous criteria developed by its Editorial Board, but the traditional printed book format of this edition presents several practical limitations for users: in particular, it does not allow for simultaneous visualisation of alternative materials and for fruition of alternative versions of the score, and it precludes addition of newly available source materials to existing volumes. DiCrEd is a multidisciplinary project aiming to address these limitations through the integration of the innovative instruments offered by digital humanities into _The Works of Giuseppe Verdi_, under the supervision of its general editor, Prof. Francesco Izzo (University of Southampton). DiCrEd employs the digital tools designed by the Edirom project (University of Paderborn) to develop 1) an applied model of digital critical edition with 2) an interactive system of fruition of the score, and 3) an applied model of digital critical edition of preparatory materials (sketches and drafts). The project uses Giuseppe Verdi’s French version of _Macbeth_ (1865) as a case study, making its full score commercially available for the first time. The project bears the potential to mark a turning point in the fields of musicology and textual criticism, with the long-term prospect of introducing digital instruments into the standard toolkit of the publishing industry related to 19th-century Italian opera.

Keywords: digital critical edition,edirom digital tools,casa ricordi,giuseppe verdi,textual criticism,macbeth,opera rara,publishing and recording industry
Mass Manufacture of MEAs Using High Speed Deposition Processes (MAMA-MEA)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Research and Innovation actions
Partnership: FCH2 (Art-187)
Countries involved: Italy,Germany,Germany,Slovenia,Netherlands,United Kingdom
Call: Step-change in manufacturing of Fuel Cell Stack Components (H2020-JTI-FCH-2017-1, 2017)
Start date: 2018-01-01
End date: 2021-06-30
Duration (months): 42.0
Total project cost (EUR): 3189816.0
EU funding (EUR): 3189816.0
Participants: 7
Project status: CLOSED

The market for PEM fuel cells will increase to 10’s GWs per annum from 2025. For the catalyst coated membrane (CCM), a critical stack component, continuous manufacturing processes are currently being implemented by manufacturers worldwide. Whilst these will meet CCM demand for the next 10 years, the growing requirement for increased numbers of CCMs thereafter necessitates a manufacturing step-change, both in terms of cost and capacity. MAMA-MEA will address this by assembling a consortium with extensive knowledge and expertise both of fuel cell technology and manufacturing in the digital coating and printed electronic industry, to develop the highly innovative concept of an additive layer manufacturing (ALM) process for the edge-sealed CCM. The key CCM components (anode and cathode catalyst layers, ion-conducting membrane and edge seals) will be deposited with high precision and speed, one component layer on top of the other, and just in the areas of the CCM where they are required for functionality. Preliminary one-off prototypes have established the feasibility of the approach, and patent applications have been filed. MAMA-MEA will develop this innovative ALM process from MRL3 to MRL 6, by integrating the CCM components in to a single continuous roll-to-roll manufacturing process and validating the sealed CCMs in two full-size stationary application PEM fuel cell stacks. A key project objective will be an increase in the manufacturing rate of over 10 times compared to the state-of-the-art process, whilst also increasing material utilisation to 99%, and the product quality, and thus yield, to over 95%. Overall, sealed CCM direct materials and manufacturing costs will be reduced by up to 58% in the new CCMs. The project will also conduct comprehensive ex-situ characterisation and in-situ fuel cell performance and durability testing and provide an engineering design of an ALM sealed CCM production line, including quality control methodologies.

Keywords: additive layer deposition process for sealed ccm,high speed ccm manufacturing process with high volume throughput,materials utilisation and quality,lamination and seal addition process,pemfc