Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Organizing, Promoting and ENabling HEritage Re-use through Inclusion, Technology, Access, Governance and Empowerment (OpenHeritage)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Cultural heritage
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Germany,Italy,Ukraine,Germany,Austria,Poland,Belgium,Hungary,Netherlands,United Kingdom,Portugal
Call: Innovative financing, business and governance models for adaptive re-use of cultural heritage (H2020-SC5-2017-OneStageB, 2017)
Start date: 2018-06-01
End date: 2022-09-30
Duration (months): 52.0
Total project cost (EUR): 4992812.5
EU funding (EUR): 4992812.5
Participants: 16
Project status: CLOSED

OpenHeritage aims at developing and testing an inclusive governance model and a supporting toolbox for the adaptive re-use of cultural heritage assets. It builds on the role of communities and the possibility of empowering them in the redevelopment process based on the concepts of heritage community and participatory culture. The project operates with an open definition of heritage, not limited to listed assets but also involving those buildings, complexes, and spaces that have a symbolic or practical significance for local or trans-local heritage communities. Inclusiveness also means the incorporation of a coalition of stakeholders into the re-use and maintenance process, the integration of resources involving new financial and economic models, and working with the local social, environmental, administrative, and economic context of the heritage sites. Territorial integration is an essential element as well: the planning process goes beyond a building or a site to contribute to the transformation of wider areas. OpenHeritage connects diverse cases across Europe, involving sixteen Observatory Cases (OCs), which are adaptive re-use projects that are studied and compared in-depth, and six Cooperative Heritage Labs (CHLs), on-going projects overseen by consortium partners, where it co-creates and tests its inclusive model. The cases are situated in a variety of urban, peri-urban, and natural environments, and include diverse heritage assets. OpenHeritage will launch a website (Heritage Point) to provide a forum for engagement and support resource integration at the CHLs, and will create a database of macro- and micro-level research results, connecting systematically collected information on the regulatory framework all over Europe with current heritage re-use practices as analyzed in the OCs . Using the OCs and CHLs as starting points, OpenHeritage establishes a system of dissemination to support the uptake of innovation in adaptive heritage re-use.

Keywords: heritage community,local identity,crowdsourcing,resource integration,inclusive adaptive re use,sustainability,open dialogue,public private people partnership,governance of the commons
Disordered and strongly-correlated systems: a new theoretical approach (SCP-Disorder)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

A primary tool to understand the properties of matter is Density Functional Theory (DFT), a reformulation of the many-electron Schroedinger equation based on a functional of the electronic density (rather than the wave-function). Although such formulation is in principle exact, its practical implementation has to rely on approximations, which, despite being successful in explaining many properties of complex molecules and condensed matter, fail when correlation among electrons becomes important. In recent years, the hosting group has developed a formalism to deal with strong correlation in density functional theory, based on the exact DFT limit of infinite coupling strength. The formalism has also been extended to bosonic systems with different kind of long-ranged repulsive interactions with very promising proof of principle results. The underlying fixed point equations that need to be solved are non-standard and very little work on the numerical side (with the exception of primitive proof of principle implementations) has been done so far. The researcher in this project is an applied mathematician with outstanding track record in designing numerical algorithms for several different physical problems. In particular, he has developed a new method to solve the non-linear Schroedinger one-particle equations, called spectral renormalization method, which is the perfect tool to solve the fixed point problem related to the strong-coupling limit of DFT. In this project we will put together the expertise of the researcher and of the host to bring to full maturity the new theoretical framework of DFT for strongly-correlated systems. In particular, we plan to apply the new methodology to study systems with disorder, analyzing Anderson localization in the presence of strong correlation.
Clinical proof of concept through a randomised phase II study: a combination of immunotherapy and stereotactic ablative radiotherapy as a curative treatment for limited metastatic lung cancer (IMMUNOSABR)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Italy,Italy,Belgium,Belgium,Belgium,Belgium,France,Netherlands,Netherlands,Netherlands,Denmark,United Kingdom
Call: New therapies for chronic diseases (H2020-SC1-2016-RTD, 2016)
Start date: 2017-01-01
End date: 2024-12-31
Duration (months): 96.0
Total project cost (EUR): 5994176.25
EU funding (EUR): 5994176.25
Participants: 22
Project status: SIGNED

IMMUNOSABR is geared towards opening up a new paradigm in treating metastatic cancer by obtaining clinical proof of concept for a novel bi-modal curative treatment strategy. High precision stereotactic ablative radiotherapy (SABR) is combined with immunotherapy to form a powerful synergistic anti-tumour strategy. The approach relies on the direct cytotoxic effect of SABR, the abscopal effect of radiation observed at distance from the irradiated metastatic site(s), and the effect of the tumour-specific immunocytokine L19-IL2 (watch our animation explaining the concept at https://youtu.be/6wDE6RkrikA). Palliative treatment is the current standard of care for patients with metastatic non small cell lung cancer (NSCLC), unless there is an actionable mutation. By using the concept of limited metastatic disease (≤10 sites, WHO 0-1: “oligo+”) we aim to develop a therapy with curative intent. IMMUNOSABR will gather evidence for the clinical efficacy of our bi-modal treatment strategy in a multicentre randomised phase II study (clinicaltrials.gov no. NCT02735850) in patients with limited metastatic NSCLC. IMMUNOSABR is complemented by two strong biomarker work packages which focus on developing an ambitious personalised biomarker strategy, to identify patients who can benefit from the novel treatment strategy. This includes promising non-invasive imaging techniques and state-of-the-art immunological monitoring approaches on tumour tissue and blood. IMMUNOSABR will spur further development of L19-IL2 as a commercial drug and translate the bi-modal treatment strategy towards clinical implementation.

Keywords: immunotherapy,sabr,l19 il2,lung cancer,metastatic cancer
YouBeep – InStore mobile shopping and analytics (YouBeep)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Portugal
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2015-02-01
End date: 2015-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

This project is YouBeep, a patented new checkout system, available free to use with a smartphone, expected to change the way people do their shopping in a retail store, allowing checkout a full shopping cart in under a minute. The long queues and waiting time at checkout lines are a key factor in customer satisfactions, and effectively represent a real high cost for retailers worldwide. Our proposal addresses this issues. Shoppers will be able to scan their items as they shop, saving time, while keeping the control over the overall amount to be paid, and their grocery list. At checkout, the shopper just needs to use their phone at any available checkout, by scanning a Qrcode. YouBeep is supported by a hardware component (patented USB device), mobile App and a cloud solution. It allows integration in any POS systems and zero software integration. Installation is simply connecting a USB cable, and all loyalty and couponing programs are still supported. The potential market for the product is very promising. The overall market for this product overlaps and greatly exceeds the market of self-checkout system that is growing at a rate of 15% per year. YouBeep usage data provide valuable analytics to retailers and Brands, and effectively leverages retailers, by providing top innovative retail technology, usually only available to top retailers, to more challenging retailers, at a viable cost, increasing EU competitiveness. The company has made an agreement with the major retailer in Portugal, for a public Pilot Trial at their stores. The objectives set for the feasibility study are validation of user traction in a meaningful pilot trial at several stores, Retailer validation, and creation of a business and marketing plan, including pricing model. In addition to this we also intend to progress and make sure our project takes the necessary steps to be eligible for Phase 2 funding of SME Instruments.

Keywords: mobile technology,new self checkout system,disruptive retail solution,shopping process
Market introduction of an innovative wearable device, consisting of a novel running shoe with embedded electronics providing real-time biomechanical feedback to reduce risk of injuries (RUNSAFER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2015-06-01
End date: 2015-10-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The world of running is experiencing a boom. More and more runners are taking up the sport, with approximately 36% of 15 to 65 year-old Europeans (accounting for 80 Million people) taking the streets, parks, forests, and gyms. However, many people start practicing running and then stop: injuries are the main reason not to run for approximately 60% of European runners. With the objective of developing an innovative and disruptive solution to prevent and reduce running injuries and to increase market competitiveness by exploiting afterwards the business opportunity, New Millennium Sports S.L. (commercially known as KELME) as the major Spanish manufacturer and distributor of sportswear, footwear and equipment for sports, participated in the FP7 Research for the Benefit of SMEs RUNSAFER project. Successfully finalised in October 2014, KELME and its supply chain count now with a functional prototype of RUNSAFER, consisting of a running shoe with embedded technology to measure biomechanical parameters of running while providing real-time feedback and training recommendations to the runner in order to prevent and reduce running injuries. Our overall objective is to convert RUNSAFER prototype into a commercially-ready wearable device to increase competitiveness and market share and to strengthen our international expansion, becoming the first sport footwear manufacturing company to offer this added-value product. In Phase 1 we need to assess the technical and economic viability of optimising and industrialising the different hardware, software and electronic components composing RUNSAFER system, including the development of an elaborated business plan. In Phase 2, KELME will optimise and miniaturise RUNSAFER system, adjust the algorithms to detect risk of injury from the biomechanical parameters of the runner, and perform a pilot demonstration on the manufacturing process and logistics in an operational environment.

Keywords: sports biomechanics,running,injury risk prevention,real time feedback to the runner,training recommendations,running shoes with embedded technology,wearable measuring system
Plasmonic Electronically Addressable super-Resolution: Accelerating the in-depth understanding of biomedical processes at the nanoscale via a novel real-time, optical limit-breaking imaging technology (PEAR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Ireland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-10-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In the life-sciences, the fight against life-threatening diseases, including cancer, requires the ability to look into cells at a resolution of 30 nm, a challenge which is unachievable by current optical microscopes. Cancer Research Cambridge, UK identifies this need as a key unmet requirement in understanding mechanisms of important biological processes. PEARlabs Technologies Ltd. have developed a ground-breaking optical chip which permits super-resolution imaging capable of visualizing cellular structures far beyond the diffraction-limit of visible light, by exploiting addressable plasmonic elements. This is a disruptive technology which will enable unprecedented capabilities for life sciences researchers in industry and academia to understand sub-cellular mechanisms at < 25 nm resolution and at real-time acquisition speeds, a full magnitude better than is currently achievable. This SME Instrument feasibility study will lead to a roadmap with investors to fund the seed round and thus to enable rapid growth. PEARlabs have developed a photonic chip which can easily be integrated into the sample stage of an optical microscope with the goal to provide next-generation resolution at 25 nm. The resulting system works in a biocompatible environment, is label-free and therefore enables in-vitro imaging needed for life sciences aiming for high spatial resolutions. This is a transformative technology for the life science sector, which currently spends over $1.8 billion a year on optical imaging, with ultra-high-resolution devices typically in the range of €350,000 - 1 million for single high-end microscope systems. The embedded, highly innovative technology presents an opportunity for an innovative European SME to become a world leader in Super Resolution imaging (SR-imaging) building on patented technology, creating high value STEM and manufacturing jobs, while also enabling to solve medically relevant problems in the life sciences.

Keywords: microscopy,nanoscopy,super resolution imaging,nanotechnology,sub diffraction limit,biomedical processes
Blockchain Innovation Spaces (Block.IS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Innovation actions
Countries involved: Spain,Germany,Ireland,Serbia,Belgium,Greece,Lithuania,Netherlands,Luxembourg,United Kingdom,United Kingdom
Call: Cluster facilitated projects for new industrial value chains (H2020-INNOSUP-2018-01-two-stage, 2018)
Start date: 2019-05-01
End date: 2022-01-31
Duration (months): 33.0
Total project cost (EUR): 5453881.5
EU funding (EUR): 4913700.0
Participants: 12
Project status: CLOSED

For the EU economy to grow sustainably it needs to re-industrialise, leveraging innovation and digital intelligence. Blockchain Innovation Spaces (Block.IS) envisions to build an open and collaborative cross-border, cross-sectoral innovation ecosystem that fosters the use of this cutting-edge technology in three vital sectors for the European economy: agrifood, logistics and finance. Block.IS will bring together (connect) actors (with an emphasis on SMEs and clusters) from these three heavily interconnected sectors, with SMEs/ innovators, to catalyse their cooperation towards innovation-driven and mutual growth (boost). The catalysation is aimed at networking the members of the ecosystem, raising understanding of the benefits of blockchain technology and stimulating the creation of new blockchain-based solutions - Cluster Missions and Clusters-Innovators Assembly. Block.IS will support innovators (SMEs) all the way from ideation to commercialisation offering them tailored business and technical support as well as direct funding, through a novel funnel approach - Innovate > Experiment > Commercialise acceleration programme. As such, the project will directly foster and strengthen competitiveness of digital SMEs (that will develop the solutions) and of the clusters and SMEs of the three verticals which will use them to offer added value to their customers. The Block.IS consortium is a fusion between: Tech founders and SMEs community (F6S), sector-oriented clusters and sectoral associations (VOICT, FEDACOVA, IT-Log, DSME, FTS), international innovation and Tech-transfer specialists (INO, IDI, CIVITTA, SYN) and Blockchain tech experts (INTRA, TNO); with an outreach of >1,017,000 SME. Block.IS invests 81% of the EC budget in SMEs and 51% through Open Calls (€2,800,000)

Keywords: cluster,blockchain,agrifood,logistics,finance,smes,acceleration
Flexibility Activated Zero Energy Districts (REnnovates)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Sustainable, resource-efficient and low-carbon technologies in energy-intensive process industries
Action type: Innovation actions
Countries involved: Spain,Germany,Belgium,Poland,Belgium,Belgium,Finland,Netherlands,Netherlands
Call: Integrated approach to retrofitting of residential buildings (H2020-EeB-2015, 2015)
Start date: 2015-09-01
End date: 2018-08-31
Duration (months): 36.0
Total project cost (EUR): 6847730.0
EU funding (EUR): 5087237.62
Participants: 13
Project status: CLOSED

The Ren(n)ovates proposal focuses on the deployment and demonstration of an innovative systemic, 4-step holistic approach comprising state-of-the-art renovation with state-or-the-art smart ICT control. Deep renovation of residential buildings will be carried out including the installation of a standardised pre-fabricated energy module equipped with communication technology converting the buildings into Net Zero Energy Buildings. This can be achieved with minimal disturbance to the tenant and with minimal renovation costs for the tenant/building owner by means of an innovative business model. The inclusion of interoperable smart control strategies introduced at building- , cluster- and business level, implemented on existing software platforms and standard compliant serve to ‘unlock’ the residential energy flexibility for grid and system level services. The project addresses the call for Energy-Efficient Buildings (H2020-EeB-2015), more specifically the topic EeB-08-2015 : Integrated Approach to Retrofitting of Residential Buildings.

Keywords: zero energy renovation of residential buildings smart neighbourhoods electric flexibility
Parasites in Antarctic Krill: diversity, distribution & impact (ParaKrill)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Australia,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-09-01
End date: 2024-08-31
Duration (months): 36.0
Total project cost (EUR): 277940.16
EU funding (EUR): 277940.16
Participants: 2
Project status: SIGNED

Antarctic krill, Euphausia superba, play essential roles in the Southern Ocean. These small pelagic crustaceans are prey for most of the region’s birds, mammals, and fish, as well as influencing the carbon cycle through export to the deep sea. Additionally, krill are the target of a currently expanding commercial fishery. Sustainably managing Antarctic krill requires an understanding of the factors influencing their growth, reproduction and mortality. One such factor which remains very poorly known is the role of parasites. My recent research using new molecular tools has shown a much higher than expected diversity and prevalence of parasite infections in krill. I observed DNA sequences of a broad variety of parasites (fungi, peronosporomycetes, apicomplexa, nematodes, and ciliates) within the guts of krill, with over 10% of krill individuals containing parasite DNA. This MSCA action will build on those preliminary results – applying a combination of novel molecular approaches, traditional incubation experiments, and mathematical modelling to address three key questions: 1) What eukaryotic parasites and symbionts are found in E. superba? 2) How are parasites distributed in geographic and environmental space? and 3) What impact do parasites have on E. superba secondary production? To address these broad questions this project brings together research expertise from Australia (Australian Antarctic Division), Europe (British Antarctic Survey and the University of Stirling), and the Americas (National Polytechnic Institute of Mexico), as well as establishing new intersectoral collaborations with fisheries (Association of Responsible Krill Harvesting Companies) and tourism (Hurtigruten). The results of this research will be communicated to national and international krill fisheries management organizations – allowing the role of parasites to be taken into account to improve the sustainability of management for this key species.