Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Hydrogen Bonding Phase Transfer Catalysis (HBPTC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-07-01
End date: 2024-12-31
Duration (months): 66.0
Total project cost (EUR): 2499070.0
EU funding (EUR): 2499070.0
Participants: 1
Project status: SIGNED

The objective of the research described in this proposal is to develop a new mode of activation for catalysis leading to more sustainable catalytic processes using abundant feedstock materials. By merging hydrogen bonding and phase transfer catalysis, we propose that hydrogen bonding of an insoluble unreactive anionic nucleophile with a hydrogen bond donor catalyst will form a soluble and reactive entity now capable of carbon-nucleophile bond formation with concomitant release of the hydrogen bond donor catalyst. This activation mode is applicable to nucleophiles as simple as feedstock inorganic salts enabling challenging asymmetric bond-forming reactions in a general and predictable fashion. Inexpensive lost nucleophiles currently unusable due to poor solubility and reactivity will be reclaimed as effective reagents for asymmetric catalysis. Common inorganic salts such as sodium chloride or potassium fluoride will be transformed into high-value products such as complex pharmaceutical and agrochemical products applying operationally simple and cost effective protocols. Synergistic catalysis whereby hydrogen bonding phase transfer catalysis will work in concert with an additional catalytic cycle will be implemented to introduce new chemical transformations with these feedstock reagents, improve efficiency, and create catalytic enantioselectivity where stereocontrol is absent or challenging. This research will require the development of high performance catalysts and the understanding of catalytic mechanisms applying structural, kinetics, and computational studies. HBPTC is expected to expand the field of catalysis, and rival the efficiency of some of the most active metal, organocatalyst and biocatalyst known to date.

Keywords: hydrogen bonding catalysis,phase transfer catalysis,asymmetric catalysis,feedstock reagents
Measuring Mobile Broadband Networks in Europe (MONROE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Future Internet: Software, hardware, Infrastructures, technologies and services
Action type: Research and Innovation actions
Countries involved: Italy,Spain,Italy,Sweden,Norway,Sweden
Call: FIRE+ (Future Internet Research & Experimentation) (H2020-ICT-2014-1, 2014)
Start date: 2015-03-01
End date: 2018-07-31
Duration (months): 41.0
Total project cost (EUR): 6542418.75
EU funding (EUR): 6542418.75
Participants: 8
Project status: CLOSED

There is a strong need for objective data about stability and performance of Mobile Broadband (MBB) networks, and for tools to rigorously and scientifically assess their performance. In particular, it is important to measure and understand the quality as experienced by the end user. Such information is very valuable for many parties including operators, regulators and policy makers, consumers and society at large, businesses whose services depend on MBB networks, researchers and innovators. MONROE proposes to design, build and operate an open, European-scale, and flexible platform with multi-homing capabilities to run experiments on operational 3G/4G Mobile Broadband networks. One of the main objectives of MONROE is to use the platform for the identification of key MBB performance parameters, thus enabling accurate, realistic and meaningful monitoring and assessment of the performance of MBB networks. MONROE also provides WIFI connectivity mimicking multi-homing in smartphones with both MBB and WiFi interfaces, to allow experimenting on different access technologies as well as explore new ways of combining them to increase performance and robustness. The users of the platform are in the core of the MONROE project. First, following the FIRE’s philosophy, MONROE offers a user-oriented closed-loop system design in which the experimental platform is open to external users, and where users are incorporated early on in the experimental design process. Second, MONROE will provide Experiments as a Service (EaaS), thus lowering the barrier for using the platform to external experimenters and users, by providing well-documented tools and adjustable, flexible, high-level scripts to execute experiments, collect results, and analyze data. Interoperability with existing FIRE and FP7 measurement platforms, jointly with the MONROE's effort to develop business and funding models, will guarantee sustainability and usefulness of the platform.

Keywords: mobile broadband networks,wifi,testbed,measurements,experiments,multihoming
Electrodermal Orienting Reactivity-based Safeguard System for Early Detection of Suicide Propensity (EDOR BOX)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Sweden
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-1-2015, 2015)
Start date: 2016-03-01
End date: 2016-06-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

According to the World Health Organization there are 800,000 suicides and 10 million attempts yearly. Appallingly, suicide is the third cause of death among 15-44 years and the second in 15-29 years old. Suicide is a major burden to society emotionally, but also economically. Costs incurred by each attempt rise to €100,000. Half reduction in the number of attempts would save €20 billion to the EU alone. Depression is the disorder most commonly attributed to suicide affecting 350 M people. Antidepressants are commonly prescribed, but they prove to be insufficient if the patient is at risk of committing suicide. However, there are no reliable tests so far to distinguish depressed patients not-at-risk, from those actually at-risk of committing suicide. In response, the Swedish company EMOTRA has developed EDOR-BOX, an innovative biomarker-based device for early detection of suicide risk. Our technology analyzes brain reactivity expressed as sweat impulses when exposed to audio signals. Absent brain responses are reflected in electrodermal hyporeactivity (no electrodermal responses), which we use as a biomarker for suicide risk in depressed patients. EDOR's main objective is to market a unique tool for effective diagnosis of suicide risk in patients from all age groups. We have already demonstrated the safety and efficacy of our device in adults, with 97% sensitivity in clinical trials. Now we aim to ensure its applicability in youngsters, due to the alarming suicide rates in this population. Our method is a cost-effective solution to prevent suicide by ensuring early detection of the risk. EDOR-BOX will provide estimated revenues of €17 M five years upon introduction, with a global impact and the creation of 50 new jobs. Ultimately, EDOR-BOX will overcome the limitations in our healthcare due to the lack of non-subjective diagnostic tools to detect an early onset of suicide propensity, as well as the economic burden coming from non-detected suicidal cases.

Keywords: suicide prevention,health,young people,diagnostic device,diagnosing suicide risk,psychiatric,children mental health,electrodermo hyporeactivity,electrodermal oriented responses
Marine Ecosystem Restoration in Changing European Seas (MERCES)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Protection of the environment, sustainable management of natural resources, water , biodiversity and ecosystems
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Estonia,Ireland,Italy,Germany,Spain,Italy,Italy,Türkiye,Finland,Croatia,Norway,Greece,Belgium,France,Netherlands,Netherlands,Netherlands,Denmark,United Kingdom,United Kingdom,United Kingdom,Portugal,United Kingdom,United Kingdom
Call: More effective ecosystem restoration in the EU (H2020-SC5-2015-two-stage, 2015)
Start date: 2016-06-01
End date: 2020-11-30
Duration (months): 54.0
Total project cost (EUR): 6651117.8
EU funding (EUR): 6651117.8
Participants: 33
Project status: CLOSED

The project MERCES is focused on the restoration of different degraded marine habitats, with the aim of: 1) assessing the potential of different technologies and approaches; 2) quantifying the returns in terms of ecosystems services and their socio-economic impacts; 3) defining the legal-policy and governance frameworks needed to optimize the effectiveness of the different restoration approaches. Specific aims include: a) improving existing, and developing new, restoration actions of degraded marine habitats; b) increasing the adaptation of EU degraded marine habitats to global change; c) enhancing marine ecosystem resilience and services; d) conducting cost-benefit analyses for marine restoration measures; e) creating new industrial targets and opportunities. To achieve these objectives MERCES created a multi-disciplinary consortium with skills in marine ecology, restoration, law, policy and governance, socio-economics, knowledge transfer, dissemination and communication. MERCES will start from the inventory of EU degraded marine habitats (WP1), conduct pilot restoration experiments (WP2, WP3, WP4), assess the effects of restoration on ecosystem services (WP5). The legal, policy and governance outputs will make effective the potential of marine restoration (WP6) and one dedicated WP will assess the socio-economic returns of marine ecosystems’ restoration (WP7). The transfer of knowledge and the links with the industrial stakeholders will be the focus of WP8. The results of MERCES will be disseminated to the widest audience (WP9). The project will be managed through a dedicated management office (WP10). MERCES will contribute to the Blue Growth by: i) improving the EU scientific knowledge on marine restoration, ii) contributing to EU Marine Directives; iii) implementing the Restoration Agenda, iv) enhancing the industrial capacity in this field, v) increasing the competitiveness of EU in the world market of restoration, and vi) offering new employment opportunities.

Keywords: marine habitats,eu seas,ecosystem services,marine restoration,marine biodiversity
Career Development Fellowships in the National Technology Centre Programme (Career-FIT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Fellowship programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Ireland
Call: Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) (H2020-MSCA-COFUND-2015, 2015)
Start date: 2017-01-01
End date: 2022-12-31
Duration (months): 72.0
Total project cost (EUR): 10620000.0
EU funding (EUR): 5310000.0
Participants: 1
Project status: CLOSED

Career-FIT is a new trans-national scheme that offers an opportunity for experienced researchers to develop their careers n market focused applied research in Ireland's Technology Centres. Covering a wide range of academic and industry areas aligned with Ireland's Smart Specialisation Strategy, the 15 Centres were established to encourage greater efficiency in the interaction between researchers, industry, and the public sector, in research that promotes economic growth by its direct relevance to industry agendas. Each multidisciplinary Centre offers excellent facilities and equipment for Fellow use: experienced scientific staff to support the Fellow’s research, and extensive enterprise relationships on which market focused applied research can be progressed. Following two widely publicised calls that seek to attract the highest quality researchers with their own research proposals, the Career-FIT programme offers 50 fellowships of 36 months’ duration for incoming mobility to the Centre Hosts, with an enterprise secondment option during the Fellowship. Selection is through a transparent process based on demonstrated excellence of the applicant, potential of the research programme, host organisation capacity to provide a developmental environment, and training/career development impact of the Fellowship. Fellows are mentored by an experienced Centre mentor(s) concerned not just for their scientific progress but also their training and development in line with agreed career goals. They will also have support from a Professional Development Advisor and will further benefit from participation in a structured development training programme that targets enhancement of personal effectiveness as well as competencies relating to innovation management. As a new programme offering interdisciplinary, intersectoral and international features, the Career-FIT human resource development objectives will guarantee the development of future research and innovation leaders.

Keywords: technology centre,industrial development,enterprise,innovation,career plan
Assessing aViation emission Impact on local Air quality at airports: TOwards Regulation (AVIATOR)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Germany,Spain,Switzerland,France,United Kingdom,United Kingdom,Canada,Denmark,United Kingdom
Call: InCo flagship on reduction of transport impact on air quality (H2020-MG-2018-TwoStages, 2018)
Start date: 2019-06-01
End date: 2023-05-31
Duration (months): 48.0
Total project cost (EUR): 5573719.75
EU funding (EUR): 5103718.16
Participants: 17
Project status: SIGNED

Emissions from aircraft have adverse effects on the air quality in and around airports, contributing to public health concerns within neighboring communities. AVIATOR will adopt a multi-level measurement, modelling and assessment approach to develop an improved description and quantification of the relevant aircraft engine emissions, and their impact on air quality under different climatic conditions. Engine particulate and gaseous emissions in a test cell and on-wing from an in-service aircraft will be measured to determine pollutant plume evolution from the engine and APU exhaust. This will provide an enhanced understanding of primary emitted pollutants, specifically the nvPM and vPM (down to 10nm), and the scalability between the regulatory test cell and real environments. AVIATOR will develop and deploy across multiple airports, a proof-of-concept low cost sensor network for the monitoring of UFP, PM and gaseous species such as NOx and SOx, across airport and surrounding communities. Transport and impact of emissions from aircraft engines and APU will be monitored in this more complex environment through high fidelity and sensor measurements. Campaigns will be complemented by high-fidelity modelling of aircraft exhaust dynamics, microphysical and chemical processes within the plume. CFD, box, and airport air quality models will be applied, providing validated parameterizations of the relevant processes, applicable to standard dispersion modelling on the local scale. Working with the regulatory community, AVIATOR will develop improved guidance on measuring and modelling the impact of aircraft emissions with specific reference to UFP. Acknowledging the uncertainty surrounding health impacts of UFP, AVIATOR will work with the public health community to develop methodologies for the representative sampling of aircraft emissions. AVIATOR will provide airports and regulators with tools and guidance to improve the assessment of air quality in and around airports.

Keywords: aircraft emission measurements,aircraft plume and airport modelling,aircraft engine certification,health impact assessment,guidance for airport,svoc,nvpm
Next Generation instrument for in-depth mitochondrial status analyses (NextGen-O2k)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Austria
Call: Accelerating the uptake of nanotechnologies advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-02-01
End date: 2018-05-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Mitochondrial dysfunctions are known to be responsible for a number of heterogenous human diseases, such as neurodegenerative disorders, cardiovascular disorders, neurometabolic diseases, cancer, obesity, etc. mitochondria-related research is a growing field, as establishing the mechanisms underlying these disorders is of utmost important for their understanding and treatment. Founded in 1992 in Innsbruck (Austria), Oroboros® produces the gold standard of Oxygraphs, i.e. advanced systems for the study of mitochondrial function, which are sold in 49 countries worldwide and are used by a large scientific network (> 570 labs). With NextGen-O2k project Oroboros® is taking one step further, providing the market with the first all-in-one (i.e. integrated) instrument that allows the simultaneous measurement of several essential parameters involved in mitochondrial functions. As of today, these parameters (such as O2 flux and concentration, membrane potential, Ca2+ uptake or reactive oxygen species formation) are measured by different instruments under different conditions. In addition, NextGen-O2k includes a novel Q-redox sensor that has never been exploited before, to accurately study the redox events in the mitochondria. Up to date, Oroboros® counts with 4 prototypes of this new NextGen-O2k product (each of which has different modules in them) which have been tested at laboratory scale. The main goal of NextGen-O2k is thus to finalise the upgrade, integration and validation of all the different modules in a single instrument, so as to be ready for commercialization. In this way, NextGen-O2k will enable a faster screening of mitochondrial dysfunctions and disease by researchers and clinicians. What’s more, this project will also boost the growth of Oroboros® itself, facilitating a 40% increase in personnel and overall revenues of €42 million in 3 years after market launch.

Keywords: mitochondrial dysfunction,all in one,redox events
Optimising quality of information in RAw MAterials data collection across Europe (ORAMA)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Ensuring the sustainable supply of non-energy and non-agricultural raw materials
Action type: Coordination and support actions
Countries involved: Germany,Ireland,Spain,Belgium,Switzerland,Sweden,Hungary,Norway,Slovenia,Finland,France,Netherlands,Japan,Denmark,United Kingdom
Call: Raw materials policy support actions (H2020-SC5-2017-OneStageB, 2017)
Start date: 2017-12-01
End date: 2019-11-30
Duration (months): 24.0
Total project cost (EUR): 1731230.0
EU funding (EUR): 1731230.0
Participants: 17
Project status: CLOSED

The ORAMA project focuses on optimising data collection for primary and secondary raw materials in Member States. A cornerstone to the EIP on Raw Materials is the development of the EU knowledge base on primary and secondary raw materials, commenced by a series of European-funded projects. As the next iteration, ORAMA addresses specific challenges related to data availability, geographical coverage, accessibility, standardisation, harmonisation, interoperability, quality, and thematic coverage in Member States. ORAMA will analyse data collection methods and recommendations from past and ongoing projects to identify best practices, develop practical guidelines and provide training to meet specific needs. These actions will demonstrate how to improve datasets for mineral occurrences, minerals intelligence data, economic, technical, environmental and social data for primary and secondary raw materials. For primary raw materials, the focus is on harmonisation and improved coverage of spatial and statistical data, ensuring compliance with the INSPIRE Directive where appropriate. For Mining Waste, Waste Electrical and Electronic Equipment, End of Life Vehicles and Batteries, the focus is on developing ‘INSPIRE-alike’ protocols. The unified data model from the Minerals4EU and ProSUM projects will be applied to the datasets and outcomes will be combined with primary raw materials data. ORAMA will demonstrate how to create more robust Material Systems Analysis studies and reliable Sankey diagrams for stocks and flows of specific raw materials. Information is made accessible and compatible with the JRC’s Raw Materials Information System to feed, for instance, future Raw Materials Scoreboard and Criticality Assessment studies. In the long term, ORAMA empowers the wider EU raw materials community with necessary facts to support policy decisions and sustainable investments in the primary and secondary raw material industries.

Keywords: data collection,critical raw materials,primary raw materials,mining waste,secondary raw materials,end of life vehicles,batteries,waste electrical and electronic equipment,inspire,rmis