Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Dynamic Combinatorial Nanoparticles for Protein Surface Recognition (DCN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-IIF-2008, 2008)
Start date: 2010-01-01
End date: 2011-12-31
Duration (months): 24.0
Total project cost (EUR): 169992.41
EU funding (EUR): 169992.41
Participants: 1
Project status: CLOSED

Recent developments in genomics and proteomics have generated an urgent need for new methods of interrogating and targeting biochemical networks. In particular new means of interfering with protein-protein interactions are in high demand and of considerable therapeutic potential. New materials are needed that can recognise and bind to specific protein surfaces. We aim to develop a new approach to the recognition of proteins using individual nanoparticles and dynamic networks of nanoparticles. This requires the development of: 1. Functional nanoparticles capable of selectively recognising proteins. We will explore the potential of dynamic combinatorial chemistry to direct the functionalisation of the surface of the nanoparticles. 2. A means of translating nanoparticle-protein interactions into a signal. Our approach is to use nanoparticle networks that respond to the presence of proteins with a redistribution of their surface functionalisation, which, in turn, produces an optical readout through fluorescence resonance energy transfer. The project is critically dependent on the host&apos;s expertise on dynamic combinatorial chemistry and the applicant&apos;s expertise on the characterisation of nanostructures. The expected outcome is a conceptually new means of interfacing functional nanoparticles with biomolecules, based on an innovative molecular network approach. This systems chemistry strategy breaks with the reductionist tradition that has characterised most research in chemistry for the last centuries.

Keywords: molecular recognition,dynamic combinatorial chemistry,systems chemistry,molecular networks,nanoparticles,protein surface recognition
Identifying best practices for successful facilitation of science learning through general interest television programming (SCIENCE ON TV)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-IOF-2008, 2008)
Start date: 2010-02-01
End date: 2012-01-31
Duration (months): 24.0
Total project cost (EUR): 153377.42
EU funding (EUR): 153377.42
Participants: 1
Project status: CLOSED

Science communication is an almost non-existing field in the Israeli Academia and I see as my professional goal to spearhead its development. Therefore, the research proposed is aimed at identifying best practices for successful facilitation of science learning through general interest television programming, in order to increase the general publics&apos; science literacy. This research proposal has a strong interdisciplinary aspect: it is situated at the crossroad of science education (specifically in free choice settings) and science communication (specifically science journalism). It is planned to enable me to take advantage of my existing skills, and at the same time gain knowledge of new research methodologies. So far, my research and training has been in the field of Science Education. This discipline does share similarities with the field of science communication, such as theoretical background and research methodologies in the area of informal science education. However, notwithstanding those similarities and my personal background as a science communicator (reporter, editor and TV presenter) it is clear to me that to meet my professional goals I need the superb formal science communication training that is available in Cornell under the guidance Prof. Lewenstein. As a junior faculty member it is important for me to develop my own niche in the academic environment and in order to further my academic position I am required by my University to complete a Post Doc in another country.

Keywords: science communication,informal science education,popular science,mass media,public understanding of science,scientific literacy,television
ARCHAEOLOGICAL RESEARCH ON ANDALUCIAN POTTERY (8TH-11TH CENTURIES) (ARANPOT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2010-09-13
End date: 2012-09-12
Duration (months): 24.0
Total project cost (EUR): 172434.64
EU funding (EUR): 172434.64
Participants: 1
Project status: CLOSED

This project is intended to study pottery from the Early Medieval Vega of Granada (Spain, 8th to 11th centuries) with archaeometrical and cutting-edge approaches. The aspects researched on will be the changes in technology, distribution, use of resources and organization of pottery production. The techniques used for the study will include thin section petrography and chemical (NAA and SEM) analyses, reproduction of actual shaping techniques and comparisons with local clay samples, known collections of studied materials and ethnological examples. The results will be linked with the evolution of society and economy in the Early Medieval Vega of Granada, where great changes were taking place. These changes are related to the general process of decline of the Roman world in the Mediterranean and the emergence in the territories of Spain of an Islamic State that would be known as al-Andalus. It has been shown in an earlier work (PhD thesis defended by the applicant) that pottery production and distribution reflects these changes. The insights that this project can offer will allow a better understanding of this questions and the linking of the Andalusian pottery production and socio-economic evolution with those of the rest of the Islamic world.

Keywords: ceramics,archaeology,comparative archaeology,local history,medieval history,economic history,history of technology,social history,islamic studies,middle ages studies,chemical technology,technology
Determination of proton parton densities using early LHC data and of contrains on new physics beyond the Standard Model (LEPTON PAIRS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-IIF-2008, 2008)
Start date: 2009-09-01
End date: 2011-08-31
Duration (months): 24.0
Total project cost (EUR): 189163.26
EU funding (EUR): 189163.26
Participants: 1
Project status: CLOSED

The Large Hadron Collider (LHC) at CERN will collide protons at a centre-of-mass energy of 14 TeV. The combination of its high collision rate and centre-of-mass energy will make it possible to probe new interactions at very short distances. Such interactions might be revealed in the production of cross-sections of particles at very high transverse momentum as a deviation from the Standard Model. However, the sensitivity to new physics depends on experimental uncertainties in the measurements and on theoretical uncertainties in the Standard Model predictions. For instance, one could use single inclusive jet and lepton pair production cross-sections at low transverse momentum to constrain the parton density functions uncertainties at high transverse momentum. One of the goals of the project is to investigate by what kind of measurements or combination of measurements present theoretical an experimental uncertainties could be reduced. A particular difficulty at the LHC is the uncertainty on the luminosity of the data set used for the cross section measurement. Typically the main experimental uncertainties are due to the limited knowledge of the absolute energy scale (ES). In the case of an electron relevant for the measurement of lepton pair production, the ES can be deduced from reference reactions. In the case of jet cross section the situation is more difficult. In addition to the knowledge of the absolute ES, uncertainties arise from the non-perturbative hadronisation corrections necessary to connect the measurements to the calculation and from underlying events. The high precision measurements of lepton pairs produced at LHC will serve as a tool for understanding and calibrating the detector response. Moreover, one can extract the parton density information from the lepton pair production data and use it for the new physics effects searches.

Keywords: nuclear physics,quantum field theory
EIT based addressing of individual ions in a microtrap (EIT ADDRESSING)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-08-01
End date: 2011-10-31
Duration (months): 27.0
Total project cost (EUR): 214717.73
EU funding (EUR): 214717.73
Participants: 1
Project status: CLOSED

Recent amazing experiments with trapped ions have demonstrated the feasibility of ion based quantum computing. At the same time, these prove of principle experiments have allowed us to analyze the experimental limitations on the fidelity of each quantum operation, on its speed, as well as on the storage time of the quantum memory. Moreover, since a practical quantum computer should operate with much more qubits and more complicated algorithms, requiring more operations, these experiments have allowed to outline strategies to overcome these limits. For example, ion heating limits the decoherence time of the ion-qubits. One of the ways to ameliorate this problem is to operate the trap in the cryogenic enviroment, which requires a minituarization of the trap and its operation with a very limited optical access. Another example is the improvement of the speed of the quantum gate by increasing the ion confinement. At the same time, the smaller the separation between the ions, the worse is the addressing of individual ions using current experimental methods due to the diffraction limit of the addressing beams. In this project we plan to address these two experimental challenges. First, we plan to demonstrate the operation of a fibered micro ion trap on a chip, which is an important step towards the realization of a cryogenically cooled trap. Second, we want to experimentally demonstrate a method for addressing individual ions based on Electro-magnetically Induced Transparency. This addresing method is not restricted by the diffraction limit and therefore promises much better addressing fidelities compared to the currently existing methods. The positive realization of this project will be of a great importance not only for the ion community, but will also have an impact on the ongoing experiments with neutral atoms in optical lattices and for the solid state physics qubits, where the sub-diffraction limited addressability of individual qubits is highly desirable.

Keywords: physical sciences,quatnum physics,trapped ions,quantum information processing,subwavelenght resolution
Contextual Requirements Elicitation for Mobile Social Software (CORE-MOSOSO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-05-18
End date: 2010-07-17
Duration (months): 14.0
Total project cost (EUR): 97147.01
EU funding (EUR): 97147.01
Participants: 1
Project status: CLOSED

The proposed research is in the field of requirements engineering (RE) and supports requirements discovery for mobile social software - an emerging and exciting phenomenon in today’s software and business world. Social software is currently weaving into the fabric of daily life faster than expected and enables its users to communicate, interact, and share data with other individuals. Two famous examples of social software include Facebook and YouTube. Emerging trends within social software include: the provision of social software for mobile devices, the integration of location-based services into social software, and the integration of social software and service-centric systems. Addressing these trends and the unique nature of mobile social software will require manifold research on mobile social software engineering. The goal of the proposed project is to develop and evaluate a tool-supported requirements discovery method tailored to the needs of mobile social software. It is planned that this method will support analysts in thoroughly understanding the needs of social communities and the patterns of communication and interaction within social networks. Firstly, this method will support on-site analysts in identifying and modelling social context information relevant to early design processes in addition to gathering system requirements. Secondly, the envisioned method will make use of the contextual information to enrich requirements discovery. It is expected that such context-enriched discovery will enable analysts to gather more and more accurate requirements for mobile social software systems. The proposed research will be conducted at the Centre for Human Computer Interaction Design at the City University London, a world-leading institution in the field of RE and socio-technical systems engineering. The proposed fellowship will allow the applicant to continue his research and will support him to get a permanent position at a European research institution.

Keywords: requirements engineering,mobile social software,service and software architecture,social communities,context-awareness,mobile and pervasive computing
ANALYSIS OF SPECIATION MECHANISMS IN RNA VIRUSES (RNAVIRSPE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-IOF-2008, 2008)
Start date: 2009-07-01
End date: 2012-06-30
Duration (months): 36.0
Total project cost (EUR): 216830.42
EU funding (EUR): 216830.42
Participants: 1
Project status: CLOSED

Parasites have high socio-economic impact due to their negative effect on humans, animals and plants welfare. Parasite evolution may lead to emergence of new infectious diseases, and compromise existing disease control strategies. Viruses are one of the most important groups of parasites causing a large fraction of emerging diseases. Adaptation to new environments may lead to population diversification, including “speciation” events resulting in the appearance of new viruses. Ecological and genetic factors are important in determining virus evolution. Environmental modifications impose selection pressures, thus changes in host population density or distribution will result in the appearance of new viral strains or species. Mutation and recombination are the main mechanisms for generating genetic variability in RNA viruses: their high mutation rates allow them to evolve rapidly adapting to new environments. Exchange of gene modules between related viral strains (modular evolution) may also result in new variants with higher fitness. We will analyze the role of these evolutionary mechanisms in the processes of virus speciation using bioinformatic tools applied to genomic sequence datasets. Analyses will focus on the families Picornaviridae, Coronaviridae and Potyviridae as models for RNA virus evolution. The three families have been widely studied, as they are important human, domestic animals and wildlife, and crop pathogens, with high sociological and agronomic relevance. Sequence data, together with information on host range and geographical distribution, are available for a large number of species and strains of these families. However, despite this data availability, to date there has been no extensive analysis of the patterns and processes of RNA virus speciation. Understanding virus evolution may be of deep interest as it may help to predict and control viral epidemics, and to understand the processes leading to the emergence of new infectious diseases.

Keywords: natural sciences,evolutionary biology,computational biology,rna viruses,speciation,modular evolution
Governance and Agents in Institutional Architecture on Climate and Energy (GAIA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IIF-2008, 2008)
Start date: 2009-08-01
End date: 2010-07-31
Duration (months): 12.0
Total project cost (EUR): 110297.11
EU funding (EUR): 110297.11
Participants: 1
Project status: CLOSED

The proposed project is aiming at drawing a clear map of the effectiveness of various ongoing initiatives on climate change and energy issues, within and outside the UN framework, by focusing on governance functions and actors performing the functions, including nation states, business and industry, NGOs, scientific networks and international organizations. It further develops scenarios on mid- to long- term institutional architectures on climate and energy in view of reaching an emerging global consensus on halving global GHG emissions by 2050, and to evaluate the scenarios in terms of the amount of GHG emission reductions and their paths. In other words, this project will work on emission differentiations by using differentiation models developed through political scientific institutional scenario-making. Through this exercise, which required inter-disciplinary collaboration with emission-reduction model, environmental effectiveness of the institutions will be evaluated in comparable way. This is one of the challenges of the GAIA project, which lies in bridging the gap between studies on institutional architecture in terms of political scientific analysis and social economic and engineering models on GHG emissions reductions towards low carbon society. The project has a strong policy-orientation in Europe and Japan, both of which are the key actors in the negotiation processes on post 2012 institutional architecture on climate change as well as implementation of the Kyoto Protocol. Therefore, the results of the project, by presenting ways to enhance and link ongoing initiatives and to evaluate environmental effectiveness of them, are expected to give impacts on the actual design of post 2012 mid- to long-term institutional architecture on climate change and energy, let alone its contribution to scientific development in such disciplines as political science and international relations, and environmental policy studies.

Keywords: governance,international relations,environmental policies (climate change),greenhouse gases (climate change),institutional architecture,energy policy
Mediation of Employment Rights Disputes (MEDEMP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria
Call:  (FP7-PEOPLE-IOF-2008, 2008)
Start date: 2010-03-01
End date: 2012-02-29
Duration (months): 24.0
Total project cost (EUR): 198508.04
EU funding (EUR): 198508.04
Participants: 1
Project status: CLOSED

Mediation gives the parties in dispute the opportunity to reach a settlement without a court hearing and with the help of an independent third party, a mediator. This can provide cost-effective and quick extrajudicial resolution of disputes also in individual employment matters through informal processes tailored to the needs of the parties. The European Community institutions have made the promotion of mediation and other forms of alternative dispute resolution (ADR) a political priority: The commission presented a Green Paper on ADR in 2002 and the Directive on certain aspects of mediation in civil and commercial matters was adopted just recently in April 2008. Austria itself has passed an Act on Mediation in Civil Matters in 2003 providing a legal framework for the practise of mediation. In spite of all this efforts mediation is still used rarely in Austria to solve employment disputes though in theory most see it as a preferable alternative to lengthy and costly court procedures. Furthermore agreements resulting from mediation are more likely to be complied with voluntarily and help to preserve an ongoing employment relationship with the parties. In the outgoing phase the research will work out factors why and how mediation of individual employment disputes may be effective by analyzing the situation in New Zealand, one of the few countries worldwide which have established a compulsory system of mediation in employment matters. After establishing the legal and sociological framework, the research will analyse case data as well as conduct interviews with mediators and parties involved. The incoming phase will be dedicated to work out the commonalities and differences between the two systems of employment relations to provide a basis to transfer the findings of the outgoing phase to the Austrian environment and to put together recommendations for policy makers.

Keywords: social sciences,employment relations,mediation,alternative dispute resolution,employment law,sociology
The Aspect-Modality Interface: a Typological perspective (AMITY)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-09-01
End date: 2011-08-31
Duration (months): 24.0
Total project cost (EUR): 158989.69
EU funding (EUR): 158989.69
Participants: 1
Project status: CLOSED

In the last decades, the TAM (Tense-Aspect-Modality) categories, which refer to the three main semantic domains marked on the verb in languages, have been extensively investigated from different linguistic perspectives. One of the burning issues in the domain concerns the interconnections between the categories of Tense, Aspect, and Modality, diachronically and synchronically, at the level of grammar and that of discourse. In this area, it is almost always the interactions between tense – i.e. the location of a situation in past present or future time – and modality – i.e. the expression of the speaker&apos;s attitude towards the content of his/her utterance - which have been explored, with a notable emphasis on the relations between past tense and irrealis / epistemicity. Contrarily, the connections between aspect – the way of viewing the internal structure of a situation - and modality are scarcely studied, though the link between certain particular aspectual values (most often the imperfective aspect) and modal meaning have been sporadically pointed in some works. The aim of the proposal is thus to investigate on this new topic, i.e. the aspect-modality interface, from a synchronic and typological perspective. More precisely, we will tackle the capacity of aspectual verbal forms to produce a modal interpretation in six European (Romance and Germanic) languages, namely French, Spanish, Italian, English, German and Dutch. The objective is to account, by means of corpus analysis, for the correspondences between aspect and modality in these languages and to give a panorama of the convergences and the differences that exist both within and between each language family.

Keywords: european languages,linguistic typology,semantics,pragmatics,morphosyntax,aspect,modality