Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Open ContEnt Aware Networks (OCEAN)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Pervasive and Trustworthy network and service infrastructures
Action type: Collaborative project
Countries involved: France,Belgium,France,France,France,Germany,Poland,Switzerland,Belgium
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-02-01
End date: 2013-08-31
Duration (months): 43.0
Total project cost (EUR): 4810045.0
EU funding (EUR): 3131619.0
Participants: 9
Project status: CLOSED

OCEAN will design a new open content delivery framework that optimizes the overall quality of experience to end-users by caching content closer to the user than traditional CDNs do and by deploying network-controlled, scalable and adaptive content delivery techniques. The OCEAN architecture will clearly define light-weight signalling protocols and public interfaces between its major building blocks (“Request routing”, “Server selection”, “Content population and delivery”, “Content storage and caching”, “Content, user, network and end-devices context description and signaling”, ”Content, user, network and end-devices context awareness and adaptation”) in order to foster multi-vendor solutions and contribute to cut down content delivery cost. OCEAN will elaborate business strategies providing better investment incentives to the different types of players in the value chain (content providers, Internet service providers, CDN service providers and industrials). OCEAN will build innovative self-learning caching algorithms that meet the specifics of the highly unpredictable location and time-dependent consumption patterns and dynamically adapt to the rising popularity of future delivery services. New media-aware congestion control mechanisms based on slight, but controlled quality degradation will provide a better alternative than mere blocking of user requests. The validity and performance of these algorithms and mechanisms will be assessed through simulations, large-scale emulations and a trial in a real ISP network. To reach these objectives OCEAN combines complementary business and technical expert partners representing the whole online multimedia content delivery chain. The OCEAN partners are committed to leverage their strong position in standardization and influence on the marketplace to disseminate the project outcomes.

Keywords: multimedia content,open architectures,cdn,broadband access,caching,learning algorithms,scalable video coding,content-aware network coding,large-scale validation,sustainable business models
User-friendly ICT tools to enhance self-management and effective treatment of depression in the EU (ICT4DEPRESSION)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Towards sustainable and personalised healthcare
Action type: Collaborative project
Countries involved: Netherlands,Netherlands,Sweden,Ireland,Portugal,Portugal,Switzerland
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2013-04-30
Duration (months): 40.0
Total project cost (EUR): 3706506.0
EU funding (EUR): 2701845.0
Participants: 10
Project status: CLOSED

Major depression is currently the fourth disorder worldwide in terms of disease burden, and is expected to be the disorder with the highest disease burden in high-income countries by 2030. Estimated costs of depression are annually 177 and 147 million euro per 1 million inhabitants for major and minor depression respectively. Current treatment methods for depressive disorders can reduce the burden of this disease with about one third. The ICT4Depression consortium will develop an ICT-based system for use in primary care that will further improve patient outcomes and increase access to treatment. All technologies to be developed will be beyond state of the art and include 1) devices for monitoring activities and biosignals in a non-intrusive and continuous way, 2) treatments for depression and automatic assessment of the patient using mobile phone and web based communication, 3) computational methods for reasoning about the state of patients, progress of therapies, and the risk of relapse and 4) a flexible system architecture for monitoring and supporting people using continuous observations and feedback via mobile phone and the web. The ICT4Depression system is flexible and can easily be adapted for treatment of other mental diseases. The project will be carried out by an interdisciplinary consortium with 5 (research) organisations and 2 SME companies at the forefront of Artificial and Ambient Intelligence, wireless biosignal sensors, activity monitoring using cell phones, monitoring patient compliance with drug prescriptions, service oriented application for the health care domain, psychology, psychiatry, and internet-based psychological treatment. The project will boost European leadership in ICT-based treatment of mental illness and will provide ample opportunities for commercial exploitation.

Keywords: depression,personal support,mobile phone,wearable biosensors,medicine monitoring,reasoning methods
NEW DRUGS FOR THE TREATMENT OF PRIMARY HIPEROXALURIA (PH-1)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2009-12-01
End date: 2013-11-02
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

Primary hiperoxaluria (PH-1) is a human genetic disease consisting on a deficiency of alanine-glyoxylateaminotransferase (AGT) activity in hepatocytes. This enzyme metabolizes glyoxylate and a lack of its activity leads to an excessive production of oxalate. Oxalate accumulation damages kidney and liver functions at first and other tissues and organs later. This disease is lethal and no effective pharmacological treatment exists nowadays; renal and hepatic transplants become necessary to preserve the life of the patients. Several mutations on AGT gene, leading to protein misfolding that avoids enzymatic activity, have been described as responsible for this disease. Our objective in this project is to develop an effective treatment for PH-1, based in a strategy of pharmacological stabilization of AGT. This novel approach is the state of the art for protein misfolding, and it is based in the use of pharmacological chaperones to recover protein active conformation. In this Memory we include the design, synthesis and biological evaluation of a series of chaperones for AGT. The synthesis has been designed following a Diversity Oriented Synthesis-like scheme, based on the knowledge of the recently described enzyme active site and it is an application of the skills that the applicant acquired during her postdoctoral stay at Cambridge University (UK) as a Marie Curie IEF-Fellow. The project is a multidisciplinary approach with a synthetic chemical part to be developed at the University of Granada, where the applicant is Assistant Lecturer, and a biological part to be developed during short stays at the University of La Laguna (Canary Islands, PH-1 endemic zone) in collaboration with Prof. Eduardo Salido, a specialist in PH-1. The project deals with a topic of interest in European Research as it faces the treatment of an “orphan disease” that is endemic in some regions of Europe, and it meets a part of the therapy not fully covered by the pharmaceutical industry

Keywords: health sciences,primary hiperoxaluria,orphan disease,agt,oxalate,glyoxylate,enzyme,cofactor,sustrate,chaperones,active site,conformation,bioisoster,diversity-oriented synthesis
Multifunctional Composite Silica Nanotubes for Targeted Delivery (MUCOSINT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Türkiye
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 75000.0
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Multifunctional nanoparticles hold great promise in targeted therapy as well as other biotechnological fields such as biomolecule sensing and cell separation. The potential of these particles to controllably deliver and accumulate therapeutic and diagnostic agents to target sites in the body make them especially useful platforms for the research in various disease types. Ideal particles for these applications should be easy to synthesize, have minimal size variation and hold efficient functionalities. Combining all these properties in the nanoscale level, however, is a formidable challenge. This project proposes a new class of non-spherical nanoparticles called Multifunctional Composite Silica Nanotubes (MuCoSiNT) for targeted therapeutic delivery applications. MuCoSiNTs will be fabricated by a facile synthesis method that allows absolute control over particle dimensions and functionalities. Moreover, they comprise large inner voids that will be filled with a composite gel matrix for the targeted delivery of imaging and therapeutic agents at high payload capacities. The in vitro cytotoxicities and antitumor activities of these particles will be determined by examining their effect on cellular viabilities and growth inhibition profiles. Finally, MuCoSiNT internalization into the cells and consequent morphological changes will be confirmed using microscopic techniques.

Keywords: multifunctional nanoparticle,targeted delivery,nanotubes,cytotoxicity,antitumor activity,particle internalization
Nanophotonics for Energy Efficiency (NANOPHOTONICS4ENERGY)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Network of Excellence
Countries involved: Spain,Germany,United Kingdom,France,Italy,Spain,Türkiye,Sweden
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2015-03-31
Duration (months): 63.0
Total project cost (EUR): 3356946.0
EU funding (EUR): 2900000.0
Participants: 9
Project status: CLOSED

The Nanophotonics for Energy Efficiency proposal aims to create a virtual centre of excellence to re-orient and focus nanophotonics research towards the challenges in energy efficient applications. The network will cluster nanophotonic laboratories and research groups in Europe combining their expertise in the development of disruptive approaches to lighting and solar cell technology. The consortium consolidates know-how and resources of 9 different institutions in 6 European countries with complimentary research and development expertise, integrating more than 130 scientists, engineers, technicians and managers in nanophotonics. The project pursues a scientific bottom-up approach to ensure that novel ideas and scientific breakthroughs as well as established proof-of-concepts in academia are promoted along the value chain towards reaching their eventual goal of commercialization. Market and industrial relevance is ensured through the involvement of industry leaders in the Advisory Board. This approach complements the existing top-down, industry-driven projects like e.g. OLED100.eu. The project intends to achieve the overall long-term integration goal by coordinating three main efforts: 1. Realising a strategy for successful integration: creation of new research clusters and a virtual laboratory network that will lead to the creation of a lasting entity that will exist beyond the duration of this NoE 2. Establishing joint research: foster collaborations among the leading groups in nanophotonics for energy efficiency, interchanging knowledge and best practices, and paving the way towards the establishment of common research agendas 3. Spreading knowledge: education and training specially geared towards young researchers and technicians – both on S&amp;T issues as well as on complementary skills like communication, business, entrepreneurial or IPR skills – and dissemination towards the scientific community, industry, and the public in general

Keywords: nanophotonics,light harvesting,light generation,plasmonics,nanowired,nanoatennas,nanoaerogels,quantum dots,leds,oleds,solar cells,networking,research exchanges,training
Translational research in human epilepsies (TRHE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-03-01
End date: 2014-02-28
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The goal of this proposal is to identify the major genes and gene variants that cause human epilepsies and their comorbid traits of cognitive and behavioral impairments. The common epilepsies are complex disorders caused by a combination of susceptibility genes. To date we have identified major genes for three main classes of epilepsy that account for 30% of the population total. In this proposal we aim to (1) Search for sequence and structural variations in identified genes ELP4, BRD2 and ME2 that predispose to disease; (2) Repeat genomewide screens and fine-mapping studies for additional susceptibility loci that act in combination with identified genes; (3) Develop animal models to delineate functional effects of gene variants. The significance of this proposal is manifold. First, trait susceptibility genes discovered through study of epilepsies may contribute to common neurodevelopmental impairments in the general population, eg for reading disability. Second, genes for common epilepsies may be shared with less common but more catastrophic neuroregressive conditions. Third, our discoveries will also significantly contribute to our understanding of the mechanisms of normal and abnormal postnatal brain development. Last, we anticipate that genetic discoveries will lead to better diagnostic screening tests, prediction of risk in presymptomatic individuals, and gene-based therapeutic strategies that not only avoid the adverse effect profiles of the current generation of antiepileptic agents but also may result in cure and prevention.

Keywords: health sciences genetics neurology aetiology
Synchronising the Research Policy Dialogue to the Indian Dimension (SYNCHRONISER)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Horizontal support actions
Action type: Coordination and support actions
Countries involved: Germany,India,Spain,Belgium
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2012-06-30
Duration (months): 30.0
Total project cost (EUR): 695744.0
EU funding (EUR): 575000.0
Participants: 7
Project status: CLOSED

SYNCHRONISER will boost the impact of the EU-India research policy dialogue in ICT using Foresight techniques. A COMMITTEE of stakeholders from both regions will identify research paths for joint research priorities noted at the EU-India March 2009 Information Societies Joint Working Group. SYNCHRONISER addresses 2 objectives feeding the EU-India policy dialogue and strengthens the international dimension of their ICT research programme: i) matching EU-India co-funding opportunities; ii) long term Indian research perspectives aligned with EU priorities. A Foresight exercise will identify future R&amp;D trends to influence EU-India R&amp;D policy. Input will include a comprehensive survey of best-in-class researchers across India using Delphi research techniques as a keynote activity resulting in publication of a Trend Study and Roadmap Report at the end of the Foresight process. This Study will act as an encyclopaedia for future EU-India joint research initiatives by highlighting current joint research scenarios and long-term perspectives. The SYNCHRONISER Consortium is well-balanced and geographically well-distributed, Indo-European, public-private-partnership with in-depth knowledge of the ICT sector in both regions and is part of a broad international network of public and private organizations, research centres and universities. The Consortium will benefit from its partners’ vast experience in EU-India Horizontal Support Action projects and strong support by the Government of India’s Department of Information Technology to establish synergies with other policy dialogue initiatives (e.g. INCO-NETS, BILATS, and other EU-India ICT projects). The GoI DIT will also assist in organizing high-level events involving policy-makers. SYNCHRONISER will ensure project dissemination through events, a project website, etc. The project target groups include ICT communities, policy-makers and other stakeholders from both regions

Keywords: india,policy dialogue,ict research cooperation,steering committee,synchronization plan
Robotic ADaptation to Humans Adapting to Robots (RADHAR)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Cognitive systems, interaction, robotics
Action type: Collaborative project
Countries involved: Belgium,Germany,Austria,Switzerland,Austria,Belgium,Sweden,Belgium
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-08-01
End date: 2013-07-31
Duration (months): 36.0
Total project cost (EUR): 3292071.0
EU funding (EUR): 2418212.0
Participants: 9
Project status: CLOSED

The first autopilots in airplanes can be traced back to the beginning of the twentieth century. These devices greatly reduced the pilot’s workload by taking over parts of the navigation. The success of autopilots in reducing navigational complexity and improving safety explains the recent interest to introduce navigational assistance in other transportation means as well. However, implementing robotic navigation correction on a large scale also represents a potential safety risk for its users. For example, some plane crashes have been attributed to the incorrect estimation by pilots of the state of the plane’s automatic pilot, an effect known as mode confusion.RADHAR therefore proposes a novel framework to design human-aware adaptive autonomy that avoids mode confusion by embedding a thorough understanding of diver behaviour and estimated intention into the decision making. Through lifelong, unsupervised learning, the robot will fuse the inherently uncertain information from environment and driver perception sensors; autonomously estimate the user model and intention and calculate a human-friendly trajectory. Since human characteristics vary over time a continuous interaction between two learning systems will emerge, hence RADHAR: Robotic ADaptation to Humans Adapting to Robots. In order to apply this framework to realistic real-world scenarios, sensor models will be developed to build 3D models of the environment with estimation of dynamic obstacles’ motion and terrain traversability. To verify driver model assumptions such as focus-of-attention, the driver’s posture and facial expression will be estimated with a camera and a haptic interface. The framework will be demonstrated on a wheelchair platform that navigates in an everyday environment with everyday objects. Tests on various levels of autonomy can be performed easily and safely on wheelchairs. Evaluation will happen by a diverse and challenging population of wheelchair users who currently drive unsafely.

Keywords: human-aware adaptive autonomy,dynamic obstacle prediction,traversability analysis,unsupervised learning unsupervised learning
Improve Photovoltaic efficiency by applying novel effects at the limits of light to matter interaction (LIMA)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: Spain,Italy,Spain,Germany,Australia,Spain
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 3186950.0
EU funding (EUR): 2375000.0
Participants: 7
Project status: CLOSED

The LIMA project exploits cutting edge photonic technologies to enhance silicon solar cell efficiencies with new concepts in nanostructured materials. It proposes nano-structured surface layers designed to increase light absorption in the solar cell while decreasing surface and interface recombination loss. Integration in a back contact design further reduces these interface losses and avoids shading. The project improves light-matter interaction by the use a surface plasmonic nanoparticle layer. This reduces reflection and efficiently couples incident radiation into the solar cell where it is trapped by internal reflection. Surface and interface recombination are minimised by using silicon quantum dot superlattices in a passivating matrix. The distance between quantum dots ensures wave-function overlap and good conductivity. An effective field at the superlattice - crystalline silicon interface ensures that the cell is insensitive to the recombination velocity at this heterojunction, and further increases the collection probability in the quantum dot layer. The dots allow a fundamental efficiency enhancement due to experimentally confirmed multiple exciton generation. This mechanism increases photocurrent and can in theory raise the theoretical single junction efficiency limit from 33% to 44%. These surface plasmonic and quantum dot layers are integrated in a high efficiency crystalline silicon back contact cell. This is designed such that the space charge region is separated from the superlattice – crystalline silicon heterojunction minimising non radiative space-charge recombination. The back contacts and dielectric electrical insulator are designed to maximise back surface reflection and enhance the light trapping of incident radiation without shading losses. The project combines expertise between academic and industrial partners. The goal is a high efficiency cell using novel concepts to enhance proven cell designs.

Keywords: emerging technologies,photovoltaics,nanophotonics plasmonics nanostructured superlattice multiple exciton generation