Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Online Labour: The Construction of Labour Markets, Institutions and Movements on the Internet (iLABOUR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-09-01
End date: 2021-08-31
Duration (months): 72.0
Total project cost (EUR): 1499911.0
EU funding (EUR): 1499911.0
Participants: 1
Project status: CLOSED

World Bank, EC Joint Research Centre, and other bodies have recently highlighted the potential of online labour markets to boost employment and economic growth. While national job markets have stagnated, online labour markets that connect firms with knowledge and service workers around the world have grown up to 60% a year. An overlooked aspect of these markets is that they extricate workers and employers from national institutional frameworks, such as employment law and collective bargaining, and instead impose their own, technologically enforced institutions. For example, a leading marketplace recently instated a global minimum wage of 4.00 USD/h. With over 540,000 employers and 4,000,000 registered workers in 180 countries, this Californian company is making critical labour policy decisions that influence businesses and individuals from Berlin to Manila. The objective of this project is to lay bare the politics and institutions of these next-generation labour markets promoted with discourses of technological progress. Whose interests find expression in their institutions? Some online workers have begun to organize transnationally with the help of digital media. How do online labour movements emerge and assert power on these markets? And finally, to what extent are these relations still reducible to struggles between capital and labour, rather than more ambiguous networked models of production? We will tackle these questions through a combination of conventional social research methods and innovative Internet research methods, on both virtual research sites (online labour markets and workers' online communities) and physical research sites (market operators' premises and worker gatherings). We survey, interview, and observe designers and workers to reconstruct processes through which online markets, institutions, and movements are shaped, and "scrape" online data to quantify their influence. The results will open up important new vistas in labour policy debate.

Keywords: virtual work,telework,labour unions,internet studies,economic sociology,crowdsourcing
Efficient, Flexible Synthesis of Molecules with Tailored Shapes: from Photo-switchable Helices to anti-Cancer Compounds (FRESCO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2015-10-01
End date: 2021-03-31
Duration (months): 66.0
Total project cost (EUR): 2436379.0
EU funding (EUR): 2436379.0
Participants: 1
Project status: CLOSED

The creation of new molecular entities and subsequent exploitation of their properties is central to a broad spectrum of research disciplines from medicine to materials but progress has been limited by the difficulties associated with chemical synthesis. We are now proposing a fundamentally new strategy, which has the potential to revolutionise how we conduct complex organic synthesis. The basic C–C bond-forming step involves the reaction of a lithiated carbamate with a boronic ester to give a homologated boronic ester with complete stereocontrol. Furthermore, the reaction shows >98% efficiency in most cases and can be conducted iteratively and in one pot (up to 9 iterations has been demonstrated with full stereocontrol). We will now extend this methodology to more functionalised carbamates as this will enable the rapid synthesis of polypropionates, which are amongst the most important classes of biologically active molecules. The robust methodology is now ripe for transfer to the solid phase as this will enable the preparation of libraries of these molecules. Through applying our assembly-line-synthesis methodology to complex molecules with diverse structures, we will demonstrate its scope, robustness, and full potential. The methodology enables stereochemistry to be ‘dialled in’ to a carbon chain, which in turn controls the conformation and we will exploit this feature in the shape-selective synthesis of molecules. We will explore how the sense of helical chirality of these molecules can be switched (M to P) just with light. We will target helical molecules with specific groups at specific places for optimum binding to disrupt protein–protein interactions involved in cancer. Finally, our methodology provides ready access to a family of building blocks that represent common repeat units found in polyketides. By combining these building blocks iteratively using lithiation-borylation, we should be able to rapidly and reliably prepare complex natural products.

Keywords: asymmetric synthesis,synthetic methodology,natural products
World’s first complete motion-preservation 'Implant-less' surgical correction for Scoliosis (ImplantFreeSpine)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: United Kingdom
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-1-2014, 2014)
Start date: 2015-06-01
End date: 2015-10-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Scoliosis affects 2-3% of the world population i.e. about 12 million people in the EU. 20,000 cases of severe scoliosis are reported each year in the EU but less than 3,000 cases ever undergo surgery due to cost and complexity of the surgery. Severe cases of scoliosis are treated by spinal fusion; a major surgical procedure that makes the spine permanently rigid restricting physical activities and permanent arrest of spinal growth. The impact of spinal deformity caused by scoliosis on the quality of life before and after surgery is huge compared with other chronic conditions such as arthritis, chronic obstructive lung disease, diabetes and hypertension. Due to the need for an alternative method for better correction of scoliosis deformities we have developed novel devices and a highly innovative care model involving a safer and significantly less invasive, complete cure which preserves spinal mobility and growth potential. Our solution will result in reduced cost of treatment by over 40% because of shorter hospitalisation, reduced operating time, elimination of additional procedures and lifetime care costs. Spine surgery currently holds a €10.2 billion global market share and is estimated to grow at a compound annual growth rate of 6.9% to reach €17.5 billion by 2022. We aim to capture a market share of 0.1% in 5 years post commercialisation of our project and earn compound revenues of €42.5 million by selling our devices over the same period. In Phase 1 of this project we intend to conduct detailed planning of the testing and design optimisation phases, carry out a market study plan, identify and engage international partners and develop a draft business plan for use upon commercialisation within a period of 6 months. In Phase 2 we will develop an advanced prototype meeting relevant EU and US Medical Devices Directives, demonstrate surgical techniques, rehabilitation strategies, and post-operative procedures and also conduct introductory marketing of our devices.

Keywords: scoliosis,spine,spinal fusion
Photocatalysis to crop protection: asymmetric cascades for chiral heterocycles (PHOTOCHIRO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Food security and sustainable agriculture is a significant and current challenge to society in the face of growing global consumption. PHOTOCHIRO seeks to provide some solutions through assisting the development of more effective crop protection technology. Specifically, we aim at the synthesis of novel chiral amines, which are common motifs in biologically active molecules, by using light-driven organocatalytic cascade processes. Asymmetric organocatalysis and photochemistry, two powerful strategies of modern chemical research, have extraordinary potential for sustainably preparing the novel organic molecules required for driving innovation in the pharmaceutical and agrichemical industries. However, the control of enantioselectivity in photochemical processes poses a fundamental scientific challenge, and PHOTOCHIRO asks whether asymmetric organocatalytic photochemical cascades can be used as an effective tool for the rapid synthesis of novel chiral pyrrolidine and piperidine building blocks. The chiral molecules prepared in this project will be screened for herbicide, insecticide, and fungicide activity in a multidisciplinary collaboration with Syngenta. This fellowship brings a new collaboration to the host institution, transfers knowledge of advanced techniques in asymmetric catalysis and photochemistry to the candidate, and, in addition, knowledge of these new enantioselective photocatalytic synthetic techniques to the industrial partner. The results have the potential to increase the economic competitiveness of Europe through Knowledge and Technology Transfer and are in line with one of H2020 Societal Challenges to secure "viable food production in face of a growing world food demand". The multi-cultural and intersectoral nature of this project will broaden Dr Holden’s competencies and places her in a competitive position for her next career move.

Keywords: catalysis,organocatalysis,photochemistry,radical,cascade,heterocycle,amine,insecticide,fungicide,herbicide,agriculture,agrichemistry,aminocatalysis,pyrrolidine,piperidine
A new photonic standard component for3D sensing (K-IND)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2020-07-01
End date: 2023-01-31
Duration (months): 31.0
Total project cost (EUR): 2229375.0
EU funding (EUR): 1560562.5
Participants: 1
Project status: CLOSED

Automation of industrial production promises cost savings, quality assurance and the avoidance of inhumane working conditions in industrial production plants. But despite technological developments over the past 40 years, many industrial tasks remain, where the automation industry is still struggling. Modern sensor technologies, in particular photonic machine vision sensors, offer solution potential. And while traditional vision sensors only provide 2D information, several approaches have been developed to record 3D. But even with state of the art 3D sensors, the human eye cannot be replaced in many cases due to the complexity of products, materials, lighting conditions and shortcomings of existing technology making automation impossible. Our patented light-field lens technology will address such flaws. It is small, video-capable, compatible with existing technology, robust even in complex lighting conditions and precise. The hardware is a new optical component (the K|Lens) which can be used with any standard camera and any main lens turning the system automatically into a 3D system. The software is based on latest research results in the areas of computer vision and machine learning. With this application, we want to fund the development of a first portfolio of prototypes covering the key potential of our technology. For this purpose, the three most promising application areas with high upscale potential have been identified during a feasibility analysis under SME Instrument Phase 1. The project is planned in close collaboration with market leading cooperation partners making sure that our products fit customer requirements and that an immediate upscale potential is guaranteed through the market position of our partners. The development of our business model will evolve through three stages. In the long term, this will allow us to transform our company into a highly scalable component provider and a leader in the deployment of 3D photonics technologies in Europe.

Keywords: light field,machine vision,computer vision,sensor technology,machine learning,robotics,automation,quality control,industry 4 0
Macro and Microplastic in Agricultural Soil Systems (SOPLAS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Austria,Germany,Spain,Germany,Spain,Germany,Switzerland,Czechia,Netherlands,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 3719361.24
EU funding (EUR): 3719361.24
Participants: 11
Project status: SIGNED

Plastics have become a key component of modern agriculture, both directly, through their use in production systems, such as greenhouse cover films and silage bags, and indirectly, such as through the application of sewage sludge or compost. However, we know almost nothing about the fate of this plastic and its impact on soil functions. The SOPLAS ETN will address this critical knowledge gap, while delivering significant advances in understanding the plastic cycle within soil and supporting the development of environmental policies, agricultural practices and industrial opportunities related to mitigating the impact of plastics on the environment. More specifically, SOPLAS will: (i) adapt and optimise existing tools to detect and quantify macro- and microplastic input into agricultural soils; (ii) improve understanding of the degradation mechanisms of conventional and biodegradable plastic, as basis of optimizing used plastic materials and identifying remediation pathways; (iii) determine the impact of microplastic on soil functions and soil health; (iv) identify pathways for microplastic export from agricultural soils to freshwater ecosystems; and (v) analysis farmers’ and consumers’ willingness to reduce the input of plastic material into agricultural soils. To address these project aims and train a new generation of leading experts understanding the nexus of plastic-agriculture-soil, SOPLAS will bring together a truly multidisciplinary team of academic and industry experts, comprising economists, agronomists, hydrologists, soil scientists, microbiologists and chemists, using the most advanced state-of-the-art approaches in their respective fields. The training network will facilitate a dialogue between researchers, industry and practitioners with as ultimate goal to advance the sustainable use of plastics in European agriculture.

Keywords: microplastic,plastic,agriculture,soil,compost,sludge,irrigation,plastic mulching,microbiology,organisms,soil health,ecotoxicology,plastic economy
TOOLS FOR MAPPING HUMAN EXPOSURE TO RISKY ENVIRONMENTAL CONDITIONS BY MEANS OF GROUND AND EARTH OBSERVATION DATA (EOXPOSURE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,Argentina,Italy,Belgium,Brazil
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2016, 2016)
Start date: 2017-03-01
End date: 2022-08-31
Duration (months): 66.0
Total project cost (EUR): 283500.0
EU funding (EUR): 270000.0
Participants: 5
Project status: SIGNED

The goal of the EOxposure project is to build tools to quantify the exposure of population and economic assets to multiple risks using novel information layers from current and future Earth Observation (EO) missions, as well as the growing sensor web on the ground. The project exploits the novel concept of the human EXPOSOME, i.e. the set of exposures to which an individual is subjected through its own existence. It includes the entire history of interactions with the environment, including air and water quality, food and exercises, as well as living habits and diseases that may spread. The cutting-edge fusion of this concept with EO and sensor data aims at measuring the human exposure to threats that are external to each individual, and quantify the interactions between human beings and the environment. By building geospatial information tools upon data coming from multiple sources, at different spatial and temporal scales, the EOxposure project aims at providing free public services, enabling citizens to understand the threats to which they are exposed, and decision makers to take more informed and effective actions against them. Specifically, EOxposure will focus on threats connected to housing conditions, disease spread, as well as security and health issues in urban and peri-urban areas, where population is concentrated. The new tools will build upon the consortium expertize on nutrition- and vector-borne disease models, urban heat monitoring and material characterization, satellite data processing, and geospatial data fusion, realizing interdisciplinary working groups dedicated to the above mentioned applications. To do so, EOxposure enrolls institutions from Europe and South America, merging expertises on exposure to risk in both developed and developing countries.

Keywords: earth observation,remote sensing,risk assessment,multi source data integration
Request for Special Needs Lump Sum Allowance in the Framework of DARE project (SNLS DARE EDF)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Action type: Marie Skłodowska-Curie actions
Countries involved: Belgium
Call: MSCA Special Needs Allowance (H2020-IBA-MSCA-SNLS-2020, 2020)
Start date: 2020-11-01
End date: 2022-12-31
Duration (months): 26.0
Total project cost (EUR): 10863.75
EU funding (EUR): 10863.75
Participants: 1
Project status: CLOSED

Request of financial support to cover the additional costs that researchers/staff members with disabilities face due to the increased costs of their mobility and/or to ensure necessary assistance by third persons or for adapting their work environment.

Keywords: snls
Advanced manufacturing process to obtain a partially Bio-Resorbable Adhesive/Non-Adhesive Triple Layer Mesh for intra-peritoneal Hernia Containment (3L-HeCoMe)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Italy,United Kingdom
Call: Accelerating the uptake of nanotechnologies, advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2014, 2014)
Start date: 2015-06-01
End date: 2015-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

3L-HeCoMe aims to provide efficient and effective industrial solutions to innovate the production processes and products for hernia containment. Ventral hernia repairs in Europe are 400.000/year, but post-operative complications still occur, namely recurrence due to prosthetic displacement and adhesions between viscera and prosthetic surfaces. Considering estimated costs for each ventral hernia repair in Europe, costs due only to recurrence amount to 36.732.000 €/year. The main aim of 3L-HeCoMe Feasibility Study(FS) is the development of an innovative process supported by enabling technologies derived from other applications and by the use of advanced materials to produce a unique medical device for the Intraperitoneal Treatment of Abdominal Wall Hernias (IPTAWH). The produced IPTAWH medical device (IPTAWH-MD) aims at preventing post-surgery problems and avoiding, or decreasing, use of mechanical surgery instruments for the mesh fixation. The IPTAWH-MD will reduce the surgical duration and costs, thanks to the following characteristics: ‐ chemical adhesive properties to parietal tissues ‐ anti-adhesion properties to viscera ‐ adequate mechanical properties, ‐ partial bioresorption. FS objectives: ‐ investigate technical development, process customization and applicability ‐ qualify 3L-HeCoMe process production output and constituting materials ‐ assess market potential and penetration routes Final users are surgeons oriented towards simplified, faster and mininvasive procedure, in the global market, which amounts to about USD 500 million and has an estimated CAGR of 7.5%, bringing to 700 million in 2019. The resulting MD will substitute actual products, giving a solid position to the SME in global markets and increasing the income, with potential sales of 259.000 – 452.000 €/year from year 1 to 5. 3L-HeCoMe addresses societal issues avoiding hernia operation recurrence, improving quality of life of patients by reducing hospitalization and reducing healthcare

Keywords: hernia containment,medical device,recurrence,surgery,mesh,technology transfer,reducing healthcare cost,quality of life,advanced materials