Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Silent Air Flows in transport, buildings and power generation (FLOWAIRS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,Netherlands,Belgium,Sweden,Netherlands,Belgium,Germany,Egypt,Germany,Germany
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2011-12-01
End date: 2015-11-30
Duration (months): 48.0
Total project cost (EUR): 3752804.46
EU funding (EUR): 3752804.46
Participants: 11
Project status: CLOSED

The FlowAirS proposal is collaborative training research network. It will be focused on the generation, propagation and reduction of sound in flow ducts for transport, buildings and power generation. There is a real need for a European-wide training in this field: the FlowAirS general objective is to train by research a new generation of young researchers with multi-disciplinary skills and able to make research careers more attractive and will enhance their own career opportunities. To achieve this goal, a partnership has been established between seven academic research centres of excellence, five industrial world leaders in their respective sectors, one innovative SME and four private research institutes or consulting engineering company: the collaboration between academia and private sector representatives is a key element of the FlowAirs training research programme. The work programme is divided in 8 Work Packages (WPs). The first 2 WPs deal with sound sources mechanisms. WP3 will be focused on innovative solutions for noise reduction. Three other WPs are concerned by the different numerical procedures and system identifications that are used in flow duct systems. One of the WP deals with the dissemination of the results to European citizens, researchers and industries. The last WP is on management and training. Training activities will be organized along three main axes: 1) training through research; 2)formal training giving all the important skills needed by researchers in the field of sound in flow duct systems and 3)training through practical experience on industrial sites. By participating to FlowAirS young researchers will gain a multi-disciplinary and appropriate background in generation, propagation andreduction of sound in flow ducts. The FlowAirS project will bring to European citizens innovative solutions to reduce the noise pollutionwhich is one of the key solutions for enhancing people quality of life and health in the European Union.

Keywords: sound engineering,acoustics,gas dynamics,applied mathematics
Optimising plant polyphenols in LEGUMES for ruminant nutrition PLUS health PLUS environmental sustainability (LEGUMEPLUS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,Switzerland,Denmark,France,Netherlands,Finland
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 4097981.68
EU funding (EUR): 4097981.68
Participants: 8
Project status: CLOSED

Europe must face the Grand Challenges of climate change and global warming, which will seriously affect the production of foods, including animal feeds. Tightening supplies of energy, foods and feeds will further impact on food security. Feeding animals in Europe with large quantities of imported soyabeans is not sustainable. ‘Home-grown’ protein sources, such as forage legumes, offer a valuable alternative, but ruminant animals make inefficient use of protein from most forage legumes. LegumePlus proposes to investigate alternative forage legumes, which increase feed use efficiency through their bioactive polyphenols. In addition to tackling such sustainability issues, they will also contribute to livestock health, welfare and reduce environmental emissions. LegumePlus will study the efficacy of bioactive legumes to i) optimise ruminant nutrition, ii) reduce greenhouse gas emissions and iii) improve milk, cheese and meat quality. It will also investigate how bioactive legumes can control parasitic worms in animals. This network will enable integrated multidisciplinary and intersectoral research training. New tools for comparative genomics in plant breeding will be harnessed and exploited to benefit ruminants and the environment. A new generation of agricultural biotechnologists will be trained to work across disciplines and solve sustainability and bioresource issues. Young researchers will acquire a thorough understanding of ruminant nutrition and parasitology, analytical chemistry and plant breeding and excellent training in state-of-the-art and industrially relevant scientific skills. Close collaboration between participants from the public and private sectors will ensure that the training programme will enhance the employability of young researchers and meet employers’ requirements for interdisciplinary and transferrable skills. This will contribute to the EU policy aim of transforming Europe into an eco-efficient, knowledge based bio-economy.

Keywords: forage products,dairy animals,feed products,food products,molecular markers,greenhouse gases,farming systems,plant biology,animal parasites,polyphenols,tannins,polyphenol oxidase,analysis
Network for Integrated Cellular Homeostasis (NICHE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,Germany,United Kingdom,Germany,Spain,United Kingdom,Netherlands,United Kingdom
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 3493255.16
EU funding (EUR): 3493255.16
Participants: 8
Project status: CLOSED

There is a need for greater understanding of integrated cellular physiology to exploit cells and to tailor their activities to optimise microbial productivity in synthetic circuits and to limit microbial activity in food and pharmaceutical products. Understanding the integration of the cellular metabolic processes is fundamental to developing and exploiting cells. We have assembled a team of internationally renowned academic and industrial partners to form a training network comprising experimentalists and modellers. The partners will work synergistically to generate a cohort of well-trained young scientists with multidisciplinary skills to drive this research field forward and provide novel tools for academic and industrial research. Our focus in this training programme is a thorough understanding of cytoplasmic homeostasis, because this is integral to the functioning of individual components and whole pathways. Cytoplasmic homeostasis is amenable to both experimentation and modelling and has profound implications for the core processes of life and productivity. The research objectives are: • To advance our understanding of the homeostatic mechanisms of bacteria via predictive modelling and state-of-the-art experimental approaches. • To generate deep insights into effects of perturbation of homeostasis on the core properties of the cell: transcription, translation, metabolism and control over protein activity. • To develop novel approaches to gauge the properties of individual cells and to model the behaviour of single cells, cell collectives in biofilms and multicellular structures. • To develop new chemical and biophysical tools for the analysis of cells and protein complexes in order to understand cellular sub-structure assembly. • To map the location and dynamics of supramolecular assemblies in the cytoplasm and cell membranes. • To manipulate the productivity of the cell and engineer new, tailored activities in the cell for industrial needs.

Keywords: cytoplasmic homeostasis,systems biology,ultrastructural analysis,predictive modelling,membrane transport,gene expression and protein assembly,macromolecular crowdi
Innovative strategies for copper-free low input and organic farming systems (CO-FREE)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Collaborative project
Countries involved: Germany,Switzerland,Italy,Netherlands,Greece,France,Poland,Netherlands,Germany,France,France,Ireland,United Kingdom,Netherlands,Belgium,Denmark,Germany,Germany,Spain
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2012-01-01
End date: 2016-06-30
Duration (months): 54.0
Total project cost (EUR): 3994513.6
EU funding (EUR): 2999895.0
Participants: 22
Project status: CLOSED

The proposed project aims to develop innovative methods, tools and concepts for the replacement of copper in European organic and low input fruit, grapevine, potato, and tomato production systems. Copper-free production systems will be achieved by (i) providing alternative compounds, (ii) ‘smart’ application tools and (iii) by integrating these tools into traditional and novel copper-free crop production systems. The copper-free apple, grapevine, potato and tomato production systems will be (iv) evaluated in a multi-criteria assessment with respect to agronomic, ecologic and economic performance. CO-FREE will also develop strategies to develop (v) ‘smart’ breeding goals by development of crop ideotypes and (vi) foster consumer acceptance of novel disease-resistant cultivars by consumers and retailers. By involving farmers, advisors, plant protection industry, policy makers and researchers as well as the stakeholders of the European organic and low input sector (food supply chain, retailers, producers associations), CO-FREE will ensure a rapid development, dissemination and adoption of the copper replacement strategies. The multidisciplinary consortium proposed for the project includes 11 academic and 9 industry (all SMEs) partners from 10 European countries. All partner institutions are leaders in their respective fields and/or are leading providers of advisory services to farmers, retailers, policy makers and other stakeholders in the organic and low input sector.

Keywords: copper replacement,organic mow input farming,apple,grapevine,potato,tomato,biocontrol,inducer of resistance,sme
Dietary Fibers supporting Gut and Immune Function - From polysaccharide compound to health claim (FIBEBIOTICS)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Fork to farm: Food (including seafood), health and well being
Action type: Collaborative project
Countries involved: Netherlands,Ireland,Norway,France,Germany,Netherlands,Belgium,Sweden,United Kingdom,Italy,Sweden,Netherlands
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2012-01-01
End date: 2016-06-30
Duration (months): 54.0
Total project cost (EUR): 7849628.8
EU funding (EUR): 5974556.0
Participants: 17
Project status: CLOSED

The project goal is to support the development of functional food ingredients and products that are beneficial for the human gut & immune system and therefore of crucial importance for quality of life. The project will study the effects of specific non-digestible polysaccharides which have shown health potential in this field. The health effects of NPS will be focused around enhancing immune defence against pathogens, the reduction of infectious diseases like common cold and influenza of elderly and will make use of EFSA supported biomarkers that enable immune function claims and underpin the mechanism involved. The studied mechanisms are the innate and adaptive immune system and the possible involvement of the microbiota and microbiota-mediated products. To achieve this goal new and existing NPS will be studied for their health effects in a systematic way by developing a toolbox of dedicated assays and models that can be used by industry and authorities to study and approve food ingredients with a similar health focus. The project will: 1) perform biochemical analyses to study compounds, effect of processing and bioavailability, 2) develop standardized in vitro screening methods to be able to predict in vivo effects, 3) use dedicated in vivo and ex vivo analyses to study mechanisms of action and to validate biomarkers and 4) use and validate this knowledge in an intervention study. By combining the knowledge that will be gained from molecular, cellular and whole-organism studies, the goal will be to understand the bioactive mechanisms of these NPS and use this knowledge to design functional food products. SMEs make a very large contribution to the project, both as beneficiary of the products and as a technology service provider related to health research. This proposed project should provide the scientific basis for international nutritional organisations to recommend an immune-related functional health claim for some of the NPS studied.

Keywords: non-digestable polysaccharides,immune,microbiota,common cold,influenza,health claim
Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production (METACODE)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Life sciences, biotechnology and biochemistry for sustainable non-food products and processes
Action type: Collaborative project
Countries involved: Germany,France,Switzerland,Belgium,Germany,Austria
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2011-12-01
End date: 2015-11-30
Duration (months): 48.0
Total project cost (EUR): 3892149.8
EU funding (EUR): 2996938.0
Participants: 8
Project status: CLOSED

The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial strains, artificial industrial microbial strains will be designed. This will enable the access to genetically robust and safe strains with added/novel functionalities and topologies from renewable resources. These strains will be characterized with alternative reading of the genetic code (genetic firewall) and with predetermined chemistries (metathesis), as well as necessary robustness for efficient industrial use.

Keywords: synthetic biology,artificial cells,biotechnology,genetic code,metathesis
Next generation European system for cattle improvement and management (GENE2FARM)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Research for the benefit of specific groups
Countries involved: Italy,Norway,United Kingdom,Poland,Spain,Greece,Austria,Switzerland,Italy,Czechia,United Kingdom,Spain,Germany,United Kingdom
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 3961086.68
EU funding (EUR): 2999593.0
Participants: 19
Project status: CLOSED

The Gene2Farm project will address the needs of the cattle industry, in particular of the SMEs and end users, for an accessible, adaptable and reliable system to apply the new genomic knowledge to underpin sustainability and profitability of European cattle farming. Gene2Farm will undertake a comprehensive programme of work from statistical theory development, through genome sequencing, to address new phenotyping approaches and the construction of tools, that will be validated in conjunction with SMEs and industry partners. Advanced statistical theory and applications will use the genomic and phenotypic information to optimise and customise genomic selection, breeding and population management and between breed predictions. The project will sequence key animals and exchange data with other international projects to create the most comprehensive bovine genome sequence database. Detailed analysis of these genome sequences will define genome structure, shared alleles, frequencies and historic haplotypes, within and between populations. This information will be used to optimise the informativeness of SNP panels and select SNPs to tag haplotypes, and hence ensure that genotype information can be used within and between breeds. The project will explore the opportunities for extended phenotypic collection, including the use of automated on farm systems and will develop standardisation protocols that, in consultation with ICAR, could be used by the industry for data collection and management. Developed tools will be tested and validated by demonstration in collaboration with dairy, dual purpose, beef and minority breed organisations. Finally a dissemination programme will ensure that training needs of the industry are served from an entry level training programme for farmers to advanced summer schools for the SMEs and expert user community.

Keywords: genome-based selection,statistical theory,optimised genotyping,new phenotypes
Strengthening networking on BiomAss researcH and biowaste conversion – biotechnologY for EurOpe India inteGration (SAHYOG)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Other activities
Action type: Coordination and support actions
Countries involved: Italy,Netherlands,Germany,Netherlands,Belgium,Germany,Greece,India
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2011-12-01
End date: 2014-11-30
Duration (months): 36.0
Total project cost (EUR): 1921875.53
EU funding (EUR): 996095.0
Participants: 13
Project status: CLOSED

The main objective of the SAHYOG project is to establish a partnering initiative to coordinate research activities carried out in Europe and India on biomass production and biowaste conversion through biotechnological approaches. The integrated project activities will be carried out by a partnership of stakeholders from EU and India involving public and private organizations that conceive and fund research programmes as well as representatives from the scientific community. Strong EU-India linkages will be created between on-going and future research and innovation projects with the aim to exploit cooperation synergies for sustainable development. The project will be based on comprehensive inventories integrating research activities from Europe and India in order to identify common areas of interest as well as knowledge gaps and cooperation opportunities. The twinning of projects and short term exchanges among researchers will be important tools to strengthen collaboration and promote networking in areas of shared strategic interest. Several stakeholder workshops will provide opportunities to explore the opinions and perspectives of European and Indian scientists and R&D programme managers. Thereby, the SAHYOG project will help to identify opportunities for joint initiatives between the EU and its Member States and India in the field of biomass production and biowaste conversion. The organization of conferences and summer schools will contribute to increase the visibility of scientific excellence and the impact of innovation in the sector. Finally, a Strategic Research Agenda and a R&D road map will be developed in order to facilitate concerted planning of future joint EU-India research initiatives Thereby, pathways will be identified to promote new technologies that will drive Europe and India to an increased exploitation of biotechnology for biomass production and biowaste conversion.

Keywords: biomass conversion,biowaste valorization,biomass inventory,biotechnology,project linkages,strategic road map
Promotion of the Bio-Economy through a travelling exhibition in Europe (BIOPROM)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Other activities
Action type: Coordination and support actions
Countries involved: Austria,United Kingdom,Austria,Germany,Italy,Estonia
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2011-10-01
End date: 2015-01-31
Duration (months): 40.0
Total project cost (EUR): 1111501.8
EU funding (EUR): 993038.0
Participants: 8
Project status: CLOSED

The BIOPROM project consortium is a Co-ordination and Support Action (Supporting) for bringing together experts who work with and on new concepts for communicating Bio-Economy science to the public. One of these concepts is to address the interests and concerns of citizens through interactive exhibitions in association with science concepts with citizens´ debates and participative democracy tools. In many European countries initiatives have been started in setting up science centres, science museums and in organising national or regional events. The BIOPROM project will combine different experiences and know-how in order to develop synergetic support measures with the main goal to promote Bio-Economy in the regions. Along these lines, a BIOPROM travelling exhibition will be established and will be shown at four different science centres within the next years.

Keywords: science communication,kbbe,global change
Ion Transport Proteins in Control of Cancer Cell Behaviour (IONTRAC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,United Kingdom,Denmark,Italy,France,United Kingdom,Germany,Germany,Germany
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2011-10-01
End date: 2015-09-30
Duration (months): 48.0
Total project cost (EUR): 3925580.03
EU funding (EUR): 3925580.03
Participants: 10
Project status: CLOSED

With over 3 million new cases and 1.5 million arising deaths each year in Europe, cancer is a major public health problem with an urgent need for new therapies. This proposal builds upon mounting evidence that ion channels and transporters underlie many of the hallmarks of cancer. Thus, proteins involved in membrane transport, long known as important drug targets in other pathologies (channelopathies), are a new class of therapeutic and/or diagnostic targets in oncology. IonTraC is first to propose a systematic analysis of the expression, function, as well as therapeutic and diagnostic potential of proteins involved in ion transport (the "transportome") in cancer. This paradigm will be implemented in pancreatic ductal adenocarcinoma (PDAC) which has one of the worst prognoses of all cancers, with an overall 5-year survival rate of less than 5%. IonTraC thereby provides the framework for an inter- and supra-disciplinary training for early stage researchers in a highly innovative, exponentially growing field in oncology which will have a major impact on other disciplines such as immunology and angiology as well. The main objectives of IonTraC are: • to provide a scientific and methodological platform for supra-disciplinary training of early stage researchers in and beyond the fields of ion transport and oncology • to provide an inter-sectoral training programme with special focus on career development of young researchers • to determine the concerted expression and function of ion channels and transporters required for the progression of PDAC, and • to provide validated therapeutic and diagnostic concepts and tools that are based on transport proteins serving as novel drug targets and/or biomarkers.

Keywords: health sciences,oncology,physiology,gastroenterology,anticancer therapy,molecular markers and recognition