Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Program for Research and Innovation on Micro and Nanotechnology for Sensors (PRIMiNaS)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Tunisia,France,Spain,Germany
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 952750.0
EU funding (EUR): 952750.0
Participants: 4
Project status: SIGNED

The Center for Research on Microelectronics and Nanotechnology CRMN, is a young center active in the field of research and innovation in micro and nanotechnologies and their applications, mainly sensors development. The CRMN is located in NOVATION CITY, Technopole of Sousse (Tunisia), an innovation ecosystem in the mechatronics sector that brings together innovative companies, research centers and engineering schools. The CRMN has already acquired different equipment for physical-chemical characterization of nanomaterials (such as SEM, AFM, etc.) and is currently in the process of building a 120m2 clean room and acquiring different equipment dedicated to micro and nanofabrication (first in Tunisia). It is expected that CRMN will reinforce the activities of the industry by providing services and driving innovative research projects. In this context, CRMN is facing many challenges related to the lack of technical and managerial expertise in this domain of high specialization. Thus, strengthening the capacity of the scientific, technical, and administrative staff of CRMN is very needed. The twinning proposal comes at the right moment for CRMN since it offers an opportunity to build its capacity to become a major actor in its field of activity. In PRIMiNaS, CRMN is associated with three European leaders in the mentioned domains, namely, the Laboratory of Microelectronic Technologies (LTM), Grenoble, France, the Universidad Politécnica de Madrid (UPM), Madrid, Spain and the Laboratory of Electrical Measurements and Sensor Technology (MST), Chemnitz, Germany. This partnership will enable CRMN to increase its research excellence, to enhance its networking with European research centres and industrial stakeholders and to develop a strategy for technology transfer and research valorisation. Via PRIMiNaS, CRMN aims to make a big step towards responsible research and innovation that considers societal challenges related to nanotechnology development (education, safety, etc.).

Keywords: microelectronics,nanotechnology,mems,sensors
Cell-specific functional connectivity of cerebellar outputs for locomotor learning (IP2adapt)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 156778.56
EU funding (EUR): 156778.56
Participants: 1
Project status: CLOSED

Everyday behaviours, like mastering dance moves or hiking through uneven terrains, require motor learning. Although essential, cellular and circuit mechanisms for this type of learning are poorly understood. In the context of locomotion, learning can be induced on a split-belt treadmill, where each side of the body moves at different speeds; this is currently used as a rehabilitative therapy in patients presenting asymmetric gaits following brain damage. The receiving laboratory recently showed that mouse locomotor learning is remarkably similar to humans. Regaining gait symmetry is achieved through specific adjustments in interlimb coordination. Moreover, the laboratory demonstrated that this form of motor learning depends critically on intermediate cerebellum. Strikingly, spatial and temporal components of learning (i.e. “where” and “when” paws land) proceeded independently, suggesting that they might be dissociable at the neural circuit level. However, how cerebellar outputs act to calibrate spatiotemporal coordination between limbs is unknown. IP2adapt aims to decipher the functional connectivity of cerebellar output circuits conveying corrective calibration signals to modify locomotor movements in space and time. Specifically, we will: 1) Use advanced viral tools to map output circuits downstream of the cerebellum and identify candidates for spatial and temporal calibration signals; 2) Use high-resolution quantitative behavioural analysis and cutting-edge circuit manipulation to test specific functional roles of projection-defined subsets of cerebellar outputs in locomotor learning; 3) Use state-of-the-art recordings of these functionally-defined neurons during learning to understand how the cerebellum transforms locomotor errors into spatial and temporal calibration of limb movement. This work will reveal unprecedented insights into neural circuits that ensure the adaptability of motor commands, with direct relevance for rehabilitative therapy.

Keywords: motor learning,locomotion,cerebellum,neural circuits,viral based tracing,neural recordings,mouse
Tool for the Analysis of Information Transfer in Manuscript Cultures (TInTraMaC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Norway
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2023-08-01
End date: 2025-01-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

This PoC project aims to alleviate the hesitancy of scholars working on texts preserved in manuscripts or other handwritten media, to adopt advanced digital methodologies in their research, by developing a free, shareable, flexible, low-threshold research tool, which may be used as a starting point for researchers interested in studying the textual transmission of information in manuscript cultures. It will take the form of a pre-designed but flexible data model, data-input framework, and database solution, through which data can be queried and exported for further analysis using relevant tools for statistical and network analysis. It will be accompanied by a detailed user manual guiding users through the workflow from data input to analysis, and tutorial videos explaining in non-specialist terms to scholars of historical textual corpora the procedures leading from database design and population to the application of relevant analytical tools. It will also contain a description of best practices and recommendations for the organization of collaborative team-based project implementation. The tool will be designed in such a way as to be easily adapted to a wide range of research projects on any type of textual corpus, regardless of its language or genre. The TInTraMac research tool will be freely downloadable and non-profit, but aims to save significant time and resources for researchers and research projects focusing on large-scale textual corpora, based on handwritten sources from manuscript cultures, promoting groundbreaking research by clearly demonstrating the benefits of employing such advanced digital methods in their fields. At the same time it aims to lower the threshold of adoption by making the TInTraMac research tool freely available, and it aims to flatten the learning curve for non-specialist users by making it highly accessible.
Sustainable Trade Regimes with Europe and Africa through Mapping Innovation, New-technology and Growth-mindset (STREAMING)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Germany,Netherlands,Poland,Tunisia,Senegal,Togo,Kenya,Ethiopia,South Africa,Belgium,Serbia,Rwanda
Call: EU-African Union – towards climate-neutral, social just fair trade food systems (HORIZON-CL6-2024-FARM2FORK-01, 2024)
Start date: 2025-02-01
End date: 2028-07-31
Duration (months): 42.0
Total project cost (EUR): 4447461.25
EU funding (EUR): 4427461.25
Participants: 15
Project status: SIGNED

With a burgeoning population across Africa, characterized by a significant youth demographic, the challenge of youth unemployment persists, exacerbated by limited opportunities in the formal sector. The informal economy absorbs the majority of new entrants, offering precarious and low-quality jobs. In response, the STREAMING project aims to develop strategies for fair, healthy, and environmentally sustainable food systems across the continent. By fostering connections between basic research and practical implementation, STREAMING seeks to promote innovation and entrepreneurship among various target groups, including women, researchers, students, and farmers. Through networking platforms, innovation hubs, startup scouting, and training programs, the project aims to bridge academia-industry gaps and promote the adoption of sustainable practices and technologies in African food trade systems. Additionally, with a focus on policy analysis and recommendation, STREAMING aims to inform trade policies in Africa and Europe, with an emphasis on removing non-tariff barriers to trade and enhancing resilience against external challenges such as climate change. By integrating stakeholder perspectives, empirical research, and innovative solutions, STREAMING strives to contribute to the establishment of fair, healthy, and environmentally friendly food systems continent-wide.

Keywords: innovation,innovation hubs,capacity building,startups,women empowerment
Beyond UV: Visible-light Photocatalysis in Prebiotic Chemistry (BEYOND)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Denmark
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-04-01
End date: 2031-03-31
Duration (months): 60.0
Total project cost (EUR): 1499307.0
EU funding (EUR): 1499307.0
Participants: 1
Project status: SIGNED

This proposal aims to uncover the role of visible light in driving prebiotic chemical reactions, with a focus on polymerizations and redox processes using prebiotically relevant photocatalysts. While UV light has traditionally been emphasized in prebiotic chemistry for its high energy and efficient bond-breaking properties, it can also degrade advanced organic material, presenting a central paradox in prebiotic chemistry. In contrast, visible light, when paired with photocatalysts, may drive important chemical transformations without the need for the protective mechanisms associated with UV chemistry. The project involves synthesizing a diverse range of photocatalysts to generate a computational model capable of predicting their photoredox properties. These molecules will then be investigated as photocatalysts in selected prebiotic reactions. Additionally, I will investigate key steps of a proposed prebiotic synthesis of key redox-active molecules can be initiated by visible light photoredox catalysis. Lastly, visible light-driven reactions will be benchmarked against established UV light-initiated processes to determine whether visible light can drive similar or complementary chemistry. By completing these objectives, I will provide examples of visible-light photocatalysis in prebiotic chemistry. This will impact our understanding of how visible light contributed to the formation of life’s building blocks, offering alternative pathways to prebiotic molecule accumulation and broadening our understanding of early chemical reaction networks.

Keywords: prebiotic chemistry,photochemistry
Janus Graphene supported Single atom catalysts for ultrasensitive cytokine point of care sensors (RESPONSE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Czechia,Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-01-01
End date: 2026-12-31
Duration (months): 24.0
Total project cost (EUR): 166278.72
EU funding (EUR): 166278.72
Participants: 2
Project status: TERMINATED

Cytokines, such as TNF-α, hold immense significance as protein biomarkers, pivotal for diagnostic, prognostic, and therapeutic management across various clinical disorders like Alzheimer’s disease, sepsis, and cancer. Nonetheless, prevailing techniques like enzyme-linked immunosorbent assay (ELISA) and Polymerase Chain Reaction (PCR) prove to be expensive, time-intensive, and reliant on specialized personnel, intricate instrumentation, and infrastructure. Furthermore, the performance of present biosensing techniques necessitates refinements in terms of real-time outcomes, sensitivity, affordability, and user-friendliness. Within this context, the RESPONSE project sets out to forge an innovative approach, intertwining Janus graphene derivatives (JGDs) and Single Atom Catalysts (SACs), or atozymes, for Point-Of-Care (POC) biosensors for cytokine detection. This undertaking involves the strategic utilization of selectively and densely functionalized JGDs, serving dual roles: i) as signal transducer immobilized on a paper lateral flow electrochemical sensor (LFES), and carrying the cytokine bioreceptor (primary/capture antibody; Ab1) and ii) as signal amplifier JGDs, housing the SACs and the secondary/signal antibody (Ab2), which binds to a different epitope of cytokine. The binding between TNF-α and JGDs-Ab1 initiates the sandwich formation with SAC-JGDs-Ab2 complex at the test region. Here, the SACs catalyze the oxidation of an appropriate reporter molecule, liberating electrons and thereby significantly amplifying the signal output which can be quantified through an integrated electrode system. REPSONSE offers affordability, point of care readiness and commercialization potential. Importantly, RESPONSE’s strategy defines the blueprint for transitioning from the current, symptom-focused and late-stage diagnosis to the next-generation prognostic biomarker-guided preventative or therapeutic treatment management, and improve life-quality of millions of people worldwide.

Keywords: atozymes,janus graphene,bioreceptors,electrochemical sensor,microfluidics,cytokines
Random complexes and the Cohen-Lenstra heuristics (RaCoCoLe)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: Hungary
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 182743.92
EU funding (EUR): 182743.92
Participants: 1
Project status: SIGNED

Graph limit theory is a rapidly developing field of mathematics. Mészáros proposes to use ideas from graph limit theory to answer questions about random simplicial complexes. The motivation for investigating the cokernels of random integral matrices comes from the number theoretic conjectures of Cohen and Lenstra. Mészáros plans to make use of the fact that the questions arising studying the homology of random simplicial complexes are very similar to questions about the cokernels of random integral matrices. Thus, ideas can be transferred from one area to the other. Mészáros also proposes to investigate the expansion properties of random simplicial complexes. Many researchers at the Rényi Institute (the host institute) played a key role in developing graph limit theory and finding applications of this theory in several areas including ergodic theory, group theory, probability theory, statistical physics and computer science. Large part of Mészáros’s past and proposed projects relies on these techniques. Building on the research that he started during his three years at the University of Toronto as a postdoctoral fellow, Mészáros will bring new questions and areas where these techniques can be applied like stochastic topology. Mészáros’s work will not only provide new areas of applications, but hopefully will open new directions in graph limit theory. The arising new topics in graph limit theory can be of great interest to many members of the host institute. The fellowship would provide Mészáros an excellent opportunity for many fruitful collaborations to explore these topics further. He is also looking forward to improving his organization, management and communication skills to become a more well rounded researcher.

Keywords: random simplicial complexes,graph limits,random matrices,cohen lenstra heuristics
Protein Landscapes: The political geography of the production and consumption of animal proteins (PROTEINSCAPES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 1999684.0
EU funding (EUR): 1999684.0
Participants: 1
Project status: SIGNED

Despite the devastating effects of the meat-dairy industry on climate and environment, the production and consumption of animal-based protein is at historically high levels. I refer to this as the protein paradox. Why are we collectively unable to reduce our reliance on meat and dairy? From the extant literature, we know that changing diet is difficult, especially as the consumption of meat and dairy is culturally normalized in many societies. The literature also reveals that the meat-dairy industry has an outsize influence over consumers and governments. These explanations, however, ignore the uneven geographies of production and consumption, and how they intersect with the political contestation of meat and dairy, entwining with processes of spatial and political polarization. PROTEINSCAPES thus asks: how can the protein paradox be explained through the political geographies of the production and consumption of animal protein? The research team will pursue: (1) a quantitative study of the protein paradox and landscapes of production and consumption across all EU countries; (2) in-depth qualitative case-study of the politics of consumption in the Czech Republic, Denmark, the Netherlands, and Portugal; and (3) a cross-national comparative study of the role of geography in the political contestation of the transition away from animal protein. By extending and connecting theory on the geography of transitions and political-spatial polarization to advance a new political geographical approach to study transitions to sustainability, and by advancing the concept of protein landscapes—produced at the intersection of territories, identities and materialities—the project will further our understanding of why the transition away from animal protein is so difficult, the necessary first step in disentangling the wicked problem of the protein paradox.

Keywords: political geography
Using museum specimens to understand mushroom population genomics. (MUSHEUM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-02-01
End date: 2026-01-31
Duration (months): 24.0
Total project cost (EUR): 226751.04
EU funding (EUR): 226751.04
Participants: 2
Project status: SIGNED

Museum collections and other repositories contain a vast amount of specimens associated with metadata detailing the location, habitat and ecological observations of the specimen at the moment of collection. Since these specimens are biological tissues, DNA sequencing techniques can be used to study them. However, their application to fungi is still very limited. One of such applications is population genomics, a field where fungal study is also severely lagging behind that of plants and animals. The combination of sequences from museum specimens and fresh material will allow us to study populations of two mushroom-forming fungi, Trichaptum abietinum and Phelopillus nigrolimitatus. T. abietinum is an abundant species that is emerging as a model for population studies, with abundant information in Scandinavia. Museum samples will allow us to detect potential changes in selective forces that have affected Norwegian populations, mainly associated with landscape changes over the XXth century. P. nigrolimitatus is a Scandinavian Nearly Threatened species whose populations have been dwindling in association to land use changes. Museum samples will allow us to compare past and current genetic diversity of Norwegian populations, which will help inform conservation efforts. The project will generate SNP chips, which will help future population and conservation studies by providing a reliable and cost-efficient analytical tool. MUSHEUM will combine population genomic data with specimen metadata and ecological information to study selective pressures in the two species. Finally, MUSHEUM will make use of the combined genome skimming data generated for the design of SNP probes to generate de novo genome assemblies of the two species. This advances will allow to repurpose data from population studies for the generation of reference assemblies.

Keywords: mycology,population genomics,museomics