Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Hydrogen-Based Intrinsic-Flame-Instability-Controlled Clean and Efficient Combustion (HYDROGENATE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-06-01
End date: 2027-05-31
Duration (months): 60.0
Total project cost (EUR): 2498727.5
EU funding (EUR): 2498727.5
Participants: 1
Project status: SIGNED

Chemical energy carriers will play an essential role for future energy systems, where harvesting and utilization of renewable energy occur not necessarily at the same time or place, hence long-time storage and long-range transport of energy are needed. For this, hydrogen-based energy carriers, such as hydrogen and ammonia, hold great promise. Their utilization by combustion-based energy conversion has many advantages, e.g., versatile use for heat and power, robust and flexible technologies, and its suitability for a continuous energy transition. However, combustion of both hydrogen and ammonia is very challenging. For technically relevant conditions, both form intrinsic, so-called thermo-diffusive instabilities (very different from the often-discussed thermo-acoustic instabilities), which can increase burn rates by a stunning factor of three to five! Without considering this, computational design is impossible. Yet, while linear theories exist, little is understood for the more relevant non-linear regime, and beyond some data and observations, virtually nothing is known about the interactions of intrinsic flame instabilities (IFI) with turbulence. Here, rigorous analysis of new data for neat H2 and NH3/H2-blends from simulations and experiments will lead to a quantitative understanding of the relevant aspects. From this, a novel modeling framework with uncertainty estimates will be developed. The key hypothesis then is that combustion processes of hydrogen-based fuels can be improved by targeted weakening or promotion of IFI, and that this kind of instability-controlled combustion can jointly improve efficiency, emissions, stability, and fuel flexibility in different combustion devices, such as spark-ignition engines, gas turbines, and industrial burners. Guided by the developed knowledge and tools, this intrinsic-flame-instability-controlled combustion concept will be demonstrated computationally and experimentally for two sample applications.

Keywords: hydrogen,intrinsic instabilities,ammonia,combustion
European Hub for Advanced Therapies & Biomaterials (EHAB)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Interconnected Innovation Ecosystems
Destination: Interconnected Innovation Ecosystems
Action type: Coordination and support actions
Countries involved: Netherlands,Germany,Portugal,Spain,Sweden,Poland,Belgium
Call: Preparatory action for setting up joint programmes among innovation ecosystems actors (HORIZON-EIE-2023-CONNECT-01, 2023)
Start date: 2023-12-01
End date: 2025-02-28
Duration (months): 15.0
Total project cost (EUR): 614206.43
EU funding (EUR): 499210.75
Participants: 9
Project status: CLOSED

The ultimate goal of EHAB is to accelerate the delivery of innovative health techniques and products, in the area of advanced therapies/regenerative medicine and biomaterials to citizens and patients who need it. This innovative healthcare should be affordable for all and improve the quality of life of patients. With Advanced Therapies & Biomaterials it will be possible to have more effective and efficient healthcare for lots of common diseases, like orthopedics, cancer or cardiovascular. Currently it is very hard to bring these techniques to the market and companies face many barriers, from production challenges to regulation. Joint action at an EU level can make the difference. Ecosystems can work together to overcome the barriers of the companies to catalyze and speed up the process of bringing innovative AT&B products to the market. The first step in creating this value chain is to capitalize and connect the assets with EU innovation ecosystems and lay the foundation for an excellent partnership from different European regions. EHAB’s Vision is thus to strengthen the European landscape in advanced therapies and biomaterials (AT&B) by building a European interconnected value chain and powerhouse to making cell and tissue related therapies available to all European citizens, seizing opportunities in key parts of the AT&B value chain, consolidating EU assets, notably SMEs and increasing its international competitiveness. EHAB’s Mission is to identify regional strengths, weaknesses, gaps and needs in a joint transregional AT&B value chain and to elaborate an action plan to strengthen the performance and capacity of the innovation ecosystems, their efficient interconnection and their alignment towards EU-level priorities, jointly tackling challenges at EU, national and regional level together with the quadruple helix stakeholders from the deeptech SME community, funding agencies, investors, academia, service providers, notified bodies, policy makers, patients.

Keywords: advanced therapies,regenerative medicine,cell tissue,biomaterials smes,personalised medicine,value chain,personalized healthcare,biomaterials,regenerative medicine,advanced therapies
Identification of novel targets to improve glioblastoma therapy (INTIGT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: CLOSED

Glioblastoma (GBM) is the most common malignant primary brain tumour in adults. The current standard of care is surgical resection of GBM tumours followed by chemotherapy and ionizing radiation (IR). Despite these intense efforts, GBM tumours remain incurable and the median survival rate of GBM patients remains only ~15 months. This dismal clinical outcome underscores the urgent need for novel therapeutic strategies for GBM. At the cellular level, GBM tumours contain a rare population of self-renewing, highly invasive stem cells termed brain tumour stem cells (BTSCs) that are endowed with properties to proliferate, spur the growth of new tumours, and at the same time, evade IR and chemotherapy. Thus eradicating BTSCs in tumour bulk represents a promising approach to fight brain cancer at its root. However, there are presently no treatments targeting BTSCs in GBM. Recent preliminary data obtained by the applicant at McGill University (Montreal, Canada) led to the hypothesis that a novel signalling pathway, galectin1/HOXA5, controls BTSC behaviour and represents a promising target to eradicate BTSCs. Thus, the applicant will join the “Laboratoire de l’Angiogenèse et du Microenvironnement des Cancers” at University of Bordeaux to test this hypothesis, under the supervision of Pr. Bikfalvi. The host, the supervisor and the candidate represents the perfect match to realise this proposal and the project is designed to bring forth a two-transfer of knowledge between the host and the candidate. The advanced techniques and transferable skills that the candidate acquires through this research will largely broaden his competencies and increase his employability as an independent researcher in the field of neuro-oncology. Results generated through this proposal will be innovative and of clinical relevance for GBM patients. This study has the potential to open new therapeutic avenues and pave the way for future clinical trials for better treatment of these deadly tumours.

Keywords: glioblastoma brain tumour stem cells carbohydrate binding proteins cancer chemotherapy radiotherapy pateint derived xenografts
Developing a rating tool for APP SAfety (APPSAFE) (APPSAFE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-11-01
End date: 2024-07-31
Duration (months): 21.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

This project aims to develop a new approach for rating mental health apps, taking into account the subjective needs of users in the mental health community. In particular, our aims are to show that 1) an automatic rating of safety in relation to mental health apps is possible, and 2) such an automatic rating system can take into account subjective needs of app users. Our goal is to build a prototype of an automatic rating system for affective safety, while also demonstrating the limitations of what cannot be automated in such a rating system. The Covid-19 pandemic has driven demand for apps as key tools, either mandatory or voluntary in nature, for responding to social and scientific challenges including both mental health and public health in general. Yet we have not updated app regulation standards or rating procedures for a world where apps are often mandatory, and where people in a situation of vulnerability increasingly use apps based on business models originaging in the commercial sphere. This scaling up and the public concern over health apps during the pandemic have created an explicit need for the definition and rating of apps with regard to affective user safety. This project aims to contribute to giving apps a sounder basis in standards and regulatory clarity, and in turn to make informed trust in apps more possible.
DAMS: Environmental Conflicts between Italy and Spain in an environmental history perspective (DAMSECIS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 193643.28
EU funding (EUR): 193643.28
Participants: 1
Project status: SIGNED

Renewable energy has become a crucial issue in the current socio-ecological crisis, but in recent years its generation through large wind and solar farms is causing environmental conflicts, as has happened with dams. However, the hegemonic narratives about dams tend to be very positive and there are few analyses of them as conflict and “sacrifice zone” from an environmental history and environmental justice perspectives that consider their impact on local communities along time. There is also a lack of studies on the construction of dams in a country as a whole and comparison between countries to get an international overview. This project aims to fill these historiographic gaps, identifying the elements that turned dams into environmental conflicts, analysing their impact on local communities since their planning or construction onwards, and constructing an overview of dam building in Spain and in Italy since 1900 to the present time, adopting a comparative and international perspective and revealing what hegemonic narratives have hidden and silenced. Both southern European countries are similar in terms of climate and rainfall pattern, internal territorial differences and political history last century, and they are the 1st and the 3rd more damned countries in the EU. The reconstruction of a comparative history of dam building can allow a better understanding of the current resistance phenomena to renewable energy projects and a territorial mediation in these conflicts. The research will be based on information gathered in archives, media, written and audiovisual materials and through interviews and field trips. Carrying out the project DAMSECIS at UniBg, I will enhance my training with new skills, as territorial mediation, and methods, as prosopography, comparative history, mapping and the construction of multidisciplinary digital research infrastructure such as databases with georeferenced historical series, and it will open new career opportunities in Europe.

Keywords: dams,environmental conflicts,renewable energy,hydroelectricity,hegemonic narratives,urban rural,sacrifice zones,governance,italy,spain,fascism,francoism,environmental justice
The ACtivist, the archivist and the researcher: novel collaborative strategies of Transnational research, archIVing and exhibiting sociAl and poliTical dissent in Europe (19th -21st century) (ACTIVATE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France,Italy,Netherlands,Switzerland,Germany,Poland,Luxembourg,Austria
Call: MSCA Staff Exchanges 2023 (HORIZON-MSCA-2023-SE-01, 2023)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 966000.0
EU funding (EUR): 966000.0
Participants: 19
Project status: SIGNED

The project “The Activist, the Archivist, and the Researcher: Novel Collaborative Strategies of Transnational Research, Archiving and Exhibiting Social and Political Dissent in Europe (19th-21st centuries)” (ACTIVATE) fosters inter-sectorial and interdisciplinary collaboration through the international research cooperation of 16 academic and non-academic institutions from 7 countries across Western, Central and Eastern Europe. ACTIVATE’s objective is to develop innovative methodologies and new knowledge as well as share best practice based on the principles of diversity, inclusiveness and open science between researchers, archivists, curators and public educators through a reflective approach on social and political dissent in a long-term and comparative perspective. By focusing on the transnational circulation of people, ideas, discourse, practice and archives, ACTIVATE aims first to contribute to a new narrative on European protest and its relations with non-European spaces. Secondly, the project engages reflective archival, research and exhibiting practices to explore the role and impact of archives on different space and time scales, approaching them as an ecosystem of active agents of memory and change. Through secondments and networking, ACTIVATE partners will share their expertise and best practice on material, audiovisual and born-digital documents and data. They will organise thematic seminars, workshops, training and public programmes to increase institutional outreach that will serve as a model for future endeavours, ensuring cooperative relationships and impact on the wider community beyond the life of the project. ACTIVATE strives for new synergies between academic research and heritage institutions, fostering better knowledge, integration and promotion of dispersed cultural heritage, which European democracies need to preserve with care.

Keywords: gender studies,european history
Phase, time and correlations in free electron wave packets (Timing-FreePhase)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2025-04-01
End date: 2030-03-31
Duration (months): 60.0
Total project cost (EUR): 2457443.0
EU funding (EUR): 2457443.0
Participants: 1
Project status: SIGNED

Electron emission from matter is a widespread phenomenon in nature, with examples including the photoionization of atoms and molecules, photoemission from solids, and the release of electrons due to ionizing radiation in biology. Complete information about the emitted electrons is contained in the amplitude and phase of their wave packets. While state-of-the-art electron spectroscopy routinely accesses the amplitude of these wave packets, the phase of free electron wave packets remains inaccessible. My team and I aim to develop an experimental technique to measure the phase of free electron wave packets without interfering with their creation mechanism. This will be groundbreaking, as the phase of the free electron wave packet carries information about the quantum mechanical properties of photoionization and the electron in its bound state prior to ionization. We will accomplish this task by constructing a novel, microscopic, ultrafast free-electron-interferometer, in which replicas of the initial free electron wave packet are generated, shifted in momentum space, and brought to interference. At the heart of this innovative interferometric scheme are two crossed pulsed standing light waves that interact with the wave packet after its creation on femtosecond timescales. We will scale this approach to be applicable to correlated few-body wave packets by combining the light field interferometer with coincident multi-particle detection in a COLTRIMS reaction microscope. Employing this groundbreaking method, we will address three objectives: (1) We will investigate the time evolution of the phase of an atomic photoelectron wave packet with a linear and with a helical interferometer made from light carrying orbital angular momentum. (2) We will study wave packets emitted from molecules, including chiral molecules. (3) We will examine correlations and entanglement within two-electron wave packets and between photoelectrons and their parent ions

Keywords: photoionization,strongfield physics,attosecond science,tunnelionization,kapitza dirac effect,photoelectron spectroscopy in the gas phase,coltrims,reaction microscope
PROtotypes of Magnetic Imaging Systems for Europe (PROMISE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Innovation actions
Countries involved: Spain,Netherlands,Italy,Germany,France,Czechia
Call: Quantum sensing and metrology for market uptake (IA) (HORIZON-CL4-2024-DIGITAL-EMERGING-01-CNECT, 2024)
Start date: 2025-01-01
End date: 2028-08-31
Duration (months): 44.0
Total project cost (EUR): 5288317.5
EU funding (EUR): 4794255.0
Participants: 10
Project status: SIGNED

PROMISE is a consortium that focuses on the application of Nitrogen Vacancy (NV) in diamond quantum technology for imaging. The aim is to guide the development and use of this mature and promising quantum technology, which is known for its ease of operation. PROMISE leads the NV based quantum imaging sensors to the next level of development building widefield magnetometer prototypes to measure relevant samples into operational environments (TRL7) to foster its market uptake. The PROMISE widefield NV magnetometer excels in imaging compared to other technologies by generating magnetic field maps without scanning. This results in a faster acquisition time (orders of magnitude faster than scanning protocols), a wide field of view and increased sensitivity. This speed up in the acquisition is the key to open up its use in a wide range of new applications. The consortium is committed to leveraging the developed NV-based prototypes for a consolidated market uptake by involving relevant partners along the whole value-chain. A unified, compact, affordable and low-consumption benchtop prototype will be designed and developed without impacting performance and functionalities. Machine learning software is being developed to streamline both data acquisition and data analysis, to facilitate for non-quantum expert use of the device and paving the way to automate inspection process. PROMISE also includes expertise that will contribute to standardising designs and methods required for the industry. During the project, four use cases will validate the prototypes, impacting the semiconductor industry, material science, aerospace and biotechnology. The industry, in general, will benefit from a tool that will enable improvements in their devices, materials and production processes, as well as provide a deeper understanding of mechanisms at the atomic level. It will also monitor events and dynamics to enable more accurate predictions and address pressing challenges in various domains.

Keywords: quantum sensing,nitrogen vacancy centres in diamond,widefield magnetometer,prototypes,magnetic field maps,imaging
Innovative marine soundscape characterization to effectively mitigate ocean and sea noise pollution (SEASOUNDS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France,Norway,Italy,Denmark,Netherlands,Spain,Monaco,United States
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 2790583.2
EU funding (EUR): 2790583.2
Participants: 18
Project status: SIGNED

SEASOUNDS aims to better characterize and predict marine soundscapes, in order to provide recommendations for appropriate and proportionate underwater noise mitigation solutions, for improved know-how, decision-making and standards setting for a sustainable Blue Growth limiting the impact on marine wildlife. SEASOUNDS addresses important knowledge gaps related to understanding, characterization and modeling of the entire noise transfer chain, from the noise source (e.g. offshore foundation installation, unexploded ordnance UXO disposal, shipping) to the receiver (whether a technological tool or an animal). SEASOUNDS’ methodological approach is built around the idea that, to address effectively these complex scientific questions, we need to go beyond the underwater acoustics-related approaches. Thus, SEASOUNDS incorporates concepts, models, and tools from seismology and mechanics to: (i) develop solutions based on Distributed Acoustic Sensing (DAS) technology to monitor marine mammals and provide information on seabed properties; (ii) characterize the soundscape of eco-regions where noise pollution is poorly known and hence insufficiently regulated, and highlight the temporal noise dynamics marine life has to face; (iii) investigate methodology biases on noise assessment, biases being induced either by numerical models or by uncertainties in the environment properties; (iv) develop efficient physics-driven modeling of noise generation (including seabed vibrations) and propagation in shallow waters; (v) study the impact of noise and vibrations on marine invertebrates and plants; (vi) understand the link between exposures of individual animals and the overall quality of the habitat that the animals live in. SEASOUNDS will train the next generation of professionals with high multidisciplinary, inter-sectoral, and transverse skills, who will comprehend noise pollution issues in a holistic way, and hence be highly valuable for public organizations, policy makers, and stakeholders who have to take science-based decisions.

Keywords: underwater noise pollution,marine soundscape,bioacoustics,ecoacoustics,offshore foundation installation,uxo disposal,shipping,das technology,hpc modeling,marine mammals,marine invertebrates