Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Assembling the Cosmic Puzzle: Theoretical Insights into the Detectability of Molecular Isomers in Space (ISOCOSMOS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1419141.0
EU funding (EUR): 1419141.0
Participants: 1
Project status: SIGNED

The advent of modern space instruments and ground based radio telescopes for ice and gas-phase molecular detections has brought astrochemistry into a golden age. In just the last five years, more than 30% of all known interstellar molecules have been detected—a staggering figure for a field with a history of several decades. Along with the numbers, the chemical complexity has also grown to complex organics and aromatic molecules. However, this rapid expansion presents critical challenges for understanding interstellar chemical complexity. The most pressing of these is the increasing number of detected isomers, molecules that share the same molecular formula but differ in their structure. Predicting their abundance in the interstellar medium, a highly non-equilibrium environment, is particularly important for the interpretation of molecular inventories derived from radio astronomy. The project ISOCOSMOS aims to tackle interstellar isomerism from a theoretical approach closely connected with observations. Building on my previous experience in machine learning, ab-initio calculations, and kinetic models, I aim to predict, explain, and leverage isomeric ratios in astrophysical environments. In particular ISOCOSMOS will explore the largest laboratory in the Universe, the Taurus Molecular Cloud. ISOCOSMOS will lift current limitations in the interpretation of astrochemical observations and pave the way for a new era, guiding future discoveries and establishing better constraints on the molecular inventory of the interstellar medium, and will contribute to understand the role of isomerism in the emergence of complex, possibly prebiotic, interstellar molecules. With its interdisciplinary approach, the tools and databases developed by ISOCOSMOS will support advancements in other fields, such as atmospheric and environmental chemistry, underscoring the broad applicability of my theoretical research.

Keywords: astrochemistry,reaction mechanisms,molecular abundances,astrochemical models
Non-abelian anyons in programmable lattices (NON-ABELIAN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-08-01
End date: 2029-07-31
Duration (months): 60.0
Total project cost (EUR): 1499334.0
EU funding (EUR): 1499334.0
Participants: 2
Project status: SIGNED

Non-abelian anyons are conjectured topological quasi-particles which shatter our understanding of quantum statistics. Exchanging two such quasi-particles can transform the quantum state in a way that cannot be undone without unwinding the exchange. The exotic properties of non-abelian anyons have puzzled researchers for decades, and the robustness associated with their statistics makes them an appealing platform for topological quantum computing. Despite broad research over the past decades, non-abelian anyons defy a conclusive experimental observation. The goal of NON-ABELIAN is the realization and exploration of non-abelian anyonic quasi-particles. We will focus on two paradigmatic systems: quasi-hole excitations in Pfaffian-type fractional quantum Hall states, and Majorana edge states in the Kitaev chain. In each system, we will use control on the microscopic level to prepare the many-body ground state, as well as to isolate, braid, and fuse its quasi-particles. Using local correlations and interferometric observables, we will reveal the properties, including their fractional charge and their non-abelian statistics. The experiments are carried out on a novel type of neutral-atom platform. It makes use of ultraprecise holographic beam shaping, programmable optical tweezer arrays, and rapid ground state cooling techniques. By studying the emergence of non-abelian quasi-particles in two complementary systems, this project will shed light on an elusive type of quasi-particle from new angles. This will lead to fundamental consequences on our understanding of quantum statistics and provide microscopic insights into strongly correlated topological systems. In addition, our experiments open avenues for topological quantum computing with cold atoms.

Keywords: ultracold fermions,lithium,symmetry protected topology,optical tweezers,bosonic pfaffian,floquet engineering
Bacterial Methionine Oxidation Repair and Aging (MOR-AGE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-05-01
End date: 2025-04-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: CLOSED

Identifying the causal molecular processes of aging is a long-standing quest in biology. Oxidative stress is a conserved hallmark of senescence among living organisms, but the underlying mechanisms linking oxidative damage and aging have proved difficult to unravel. Multiple reports pinpoint Methionine oxidation as an important antioxidant system influencing the lifespan of cells. Here, I propose to develop an approach including single-particle tracking and microfludic-based single-cell imaging to visualise Methionine oxidation repair in live E. coli bacteria. Such method is currently lacking in the field and its development, although challenging, could deepen our understanding of how system-level failures emerge out of molecular damage.

Keywords: bacteria,methionine,sulfoxide,msr,single molecule imaging,microfluidic based microscopy,aging,live single cell
Artificial induction of tertiary lymphoid structures (TLS) in tumors using intratumoral mRNAs to evaluate its synergy with immune checkpoint inhibitors (TLSaRNA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: TERMINATED

Tertiary lymphoid structures (TLS) are ectopically generated lymphoid structures with some level of cellular organisation similar to the secondary lymphoid organs, characterised by having a B-cell zone adjacent to a T-cell zone. The presence of tumor immune infiltrates, especially in the form of TLS, has been linked to a better cancer prognosis in different types of tumor and improved response to immune checkpoint inhibitors (ICB). However, interestingly, not all the patients develop TLS and the cellular composition and organisation within the structures can vary. Specifically, the role of B cells in the tumor microenvironment is controversial, while some studies have reported a pro-tumoral effect, possibly through differentiation of regulatory B cells, metadata shows a strong association between the presence of a transcriptional B cell profile on the tumors and the improved patient outcome. Moreover, the presence of B cells in the tissue microenvironment is also positively associated with an improved response to ICB. However, even though these strong statistical associations and the relevance of TLS in the cancer prognosis, still little is known about the mechanisms underlying their function and the specific role of B cells in the anti-tumoral response elicited. In this proposal, we will study novel therapies for artificial TLS induction by using intratumoral injection of mRNAs encoding for specific cytokines. We will deeply characterise the synergy between immunotherapy treatments and TLS in the tumor development by using the state-of-the art spatial transcriptomics and immunophenotyping. Finally, we will decipher the function of tumor-specific B cells on the tumor microenvironment and the relevance of tumor-specific secreted antibodies in the overall anti-tumoral response. Ultimately, the knowledge generated with this proposal will provide relevant information to guide future immunotherapy treatments.

Keywords: tertiary lymphoid structures,immunotherapy,b cells
SST Sensors and Processing. Horizon Europe TOP4 (HE23-24 TOP4)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Cluster 4 other
Destination: Other Digital, Industry and Space destinations
Action type: Innovation actions
Countries involved: Spain,France,Poland,Italy,Greece,Portugal
Call: SST Sensors and Processing (HORIZON-CL4-2025-SSA-SST-IBA, 2025)
Start date: 2026-01-01
End date: 2028-06-30
Duration (months): 30.0
Total project cost (EUR): 63219907.25
EU funding (EUR): 27500000.0
Participants: 10
Project status: SIGNED

This Horizon Europe grant is to be understood within a wider context on EUSST, where other grants are being executed simultaneously with the common objective of improving the EU autonomy on Space Surveillance and Tracking. In particular, this TOP focuses on: - R&I activities are necessary in the sensor domain, both for radiofrequency (i.e., radars, etc.) and optical sensors (i.e. telescopes and innovative wide field optical sensors).. - Contribution to a consolidated and efficient EUSST sensor function. - Improve coverage area, geographical location and performance they can offer: - Ensure an optimum evolution of the configuration and use of the EUSST sensors network - Improved integration and connectivity of value added sensors, ensuring their compliance to the minimum quality requirements (including protocols, procedures, formats and calibration status). Taking into consideration the data procurement activities which are taking place in the EUSST2023-26 SpReg grant, where most of the assets providing data are telescopes providing MEO/GEO data, and the upgrades being funded under the “innovative Commercial Sensor Upgrades” cascading grants, the EU SST Partnership has decided to improve the LEO survey capabilities. In particular, the following assets will be upgraded: - ES_S3TSR (surveillance radar in Europe) - FR_GRAVES_NG (surveillance radar in Europe) - IT_FLYEYE (survey and tracking LEO telescope) - GR_ (Survey LEO telescope in Europe) - PL_POLON network (survey LEO telescope in VLA Asia, Kazajstan)

Keywords: eusst,sst,partnership,services,assets,sensors,radars,telescopes,autonomy
Resilient Cultures – Music, Art, and Cinema in Mainland China and Hong Kong (RESCUE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Netherlands
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 2497500.0
EU funding (EUR): 2497500.0
Participants: 1
Project status: SIGNED

How to be critical in a context where critique is disavowed? How to speak against power while being silenced? How to stay amidst suppression? RESCUE studies how cultural practices in the domains of popular music, contemporary art, and queer cinema, in mainland China and Hong Kong, develop resilient tactics to express their social and political discontent. It theorises resilience and cultural critique in times of intensified authoritarianism and rapid platformization. Whereas such practices can resort to a history of experiences in China to negotiate a recently intensified authoritarianism, cultural practitioners in Hong Kong are facing a compressed authoritarianism – still searching for resilient tactics. RESCUE studies indie music in Hong Kong; folk music in China; the role of official and unofficial art institutes in China and Hong Kong; socially engaged art projects in rural and urban areas in China and Hong Kong; and queer cinema and queer film festivals in China and Hong Kong. It develops a relational comparative analysis between different cultural fields, and at different localities (Hong Kong, Beijing, Shanghai, Guangzhou, Tianshui), to unpack the (im)possibilities of critique. RESCUE develops an innovative methodological toolkit, combining ethnography with textual analysis, digital methods, and collaborative research. RESCUE will establish and consolidate a network of academics, cultural practitioners, and activists in mainland China, Hong Kong, East Asia, and Europe, through multiple workshops, a podcast series, performances, screenings, and an exhibition – thereby increasing the social impact of the project. Findings will not only attest to the multivocality, diversity, and vitality of cultural production in mainland China and Hong Kong, thus pushing back against the idea of the omnipotent Chinese state, but also inspire and forge connections to other localities facing a comparable predicament (e.g. Brazil, Hungary, India, Russia, and Turkey).

Keywords: authoritarianism,resilience,critique,digitisation,mainland china,hong kong,popular music,contemporary art,queer cinema
FIRST MLOPS INTEGRATING REAL-TIME RISK MANAGEMENT, COMPLIANCE AND EXPLAINABILITY WHERE THE AI MODEL RUNS (Deeploy)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2490000.0
EU funding (EUR): 2490000.0
Participants: 1
Project status: SIGNED

Deeploy presents the world's first human-centric AI MLOps platform that integrates real-time risk management, explainability, and compliance directly within the infrastructure where models run. This ensures safe, reliable, ethical, transparent, and accountable AI deployments, instantly minimizing risk exposure and reducing the time needed to resolve incidents. Deeploy’s platform stands out by embedding these critical elements into the AI lifecycle, providing unparalleled oversight and control, which is essential in regulated industries. By leveraging advanced eXplainable AI (XAI) techniques, real-time monitoring, and bias mitigation tools, Deeploy offers a robust and user-friendly system that addresses the urgent need for ethical AI in heavily regulated industries such as finance, healthcare, and government. Our innovative approach meets regulatory requirements and builds stakeholders' trust by making AI decisions understandable and justifiable. We strive to ensure regulatory compliance with stringent laws such as GDPR and the EU AI Act, providing tools for continuous monitoring and documentation of AI models. Another critical objective is to mitigate biases in AI models, promoting fair and ethical outcomes across various applications. Our strategy includes scaling our solution across European markets, starting with the Netherlands and Germany, followed by other regions, ensuring widespread adoption and impact. This aligns perfectly with the goals of the EIC Accelerator's Human Centric Generative AI challenge, contributing substantially to the EU's digital transformation agenda. Through our platform, we aim to set new standards for responsible AI, driving positive change and fostering innovation across industries.

Keywords: fintech data protection and privacy web and information systems,database systems,information retrieval and digital,libraries,data fusion advanced computing big data
SynergistEIC: Boosting Synergies between EIC and Startup Europe (SynergistEIC)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: other EIC
Destination: Other destinations
Action type: Coordination and support actions
Countries involved: Romania,Slovakia,Portugal,Ireland
Call: Enhancing synergies between the EIC and Startup Europe (HORIZON-EIC-2021-STARTUPEU-01, 2021)
Start date: 2023-01-01
End date: 2024-12-31
Duration (months): 24.0
Total project cost (EUR): 1986176.25
EU funding (EUR): 1986176.25
Participants: 4
Project status: CLOSED

The EU takes significant measures to nurture European startups and scaleups in their growth, especially via the European Innovation Council. One its most impactful instruments, the EIC Accelerator, provides substantial financial support for SMEs, startups, spin-outs and in some cases small mid-caps. Despite the high-quality applications, the success rate is still low with only a minor fraction of applicants receiving funding. In reality, many more startups need support in creating a high-impact innovative product, service or business model. Even applicants who obtain a Seal of Excellence from the EIC Accelerator struggle to secure appropriate alternative funding from other sources. High quality support should be available to many more companies than those selected by the EIC Accelerator. SynergistEIC project is conceptualized by four partners with experience in advising technology startups and running FSTP measures. The project’s long term strategic objective is to help European digital and deep tech startups scale in the EU and globally, contributing towards EU’s autonomy in strategic sectors. This will be achieved by providing tailored, specific and hands-on support to European impact-driven startups, notably in the sector of climate-tech, green-tech, circular economy and agri-food to increase their competitiveness and readiness to succeed in EIC Accelerator. SynergistEIC project will identify and select 30 digital and deep tech startups (10 startups that are Seal of Excellence holders or those who passed Step 1 of EIC Accelerator application, and 20 non-EIC applicants), especially from Widening countries, through two waves of open calls. The team will award them with sub-grants, tailored advisory and acceleration services. It will also raise their awareness of EU funding and procurement opportunities, and will connect them with investors, and national and European innovation ecosystem actors, to boost their scalability and business performance.

Keywords: sub grants,fstp,digital,deep tech,greentech,sustainability,impact,scalability,marketing,testing,validation,acceleration,advisory,startups,mentorship,matchmaking,investment,ecosystem
See-through waveguide displays for augmented reality (AR) devices driving the next wearables revolution (Dispelix)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Finland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499999.0
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Dispelix Oy is a nanophotonics deep technology company founded in 2015 as a spin-off from VTT Technical Research Centre of Finland. Operating as a fabless company which combines pioneering software and hardware capabilities, Dispelix specializes in the design, development, and supply of optical waveguides serving as transparent displays for augmented reality (AR) wearables including glasses and other head-mounted devices. The innovative waveguide display technology offered by Dispelix is integral to materializing the AR product visions of leading global tech firms, pushing truly wearable AR devices and their benefits into widespread use. With support from the EIC, Dispelix is setting on a mission to establish itself as a pioneer in the Optical Lithography based manufacturing of diffractive waveguide displays. This revolutionary manufacturing approach is stable and cost-efficient and will allow for high-precision, fabrication of nanoscale gratings, making it suitable for the mass production of AR waveguide displays, driving the AR wearable revolution.

Keywords: augmented reality virtual reality expanded reality ar,vr,xr,waveguide displays,optical lithography,surface relief diffraction gratings diffractive optical element combiners
Fast Atomic Layer Processing (FALP)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 36.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

As part of the HORIZON EUROPE "EIC Accelerator" funding program for SMEs, the market launch of the FALP® system is to be advanced towards series production by supplementing and integrating automation modules (with a focus on wafer handling and integration into production logistics). The innovation of the system is the 2-in-1 chamber system, which makes it possible to carry out both atomic layer deposition and atomic layer etching in one process chamber without breaking the vacuum. This concept, combined with the highly innovative, patented chamber features, significantly reduces the consumption of resources. Substrate processing within the chamber is approx. 4 times faster than in conventional ALD or ALE systems due to the excellent fluidic design of the process chamber. The analyses of the coatings of the FALP prototype have already proven that the coatings can not only be processed very precisely, but also extremely evenly. As the ion energy can be specifically controlled within the chamber, the processed coatings can be highly compacted, making them stronger and more durable than conventional coatings. In order to make this technology marketable, it is essential to automate the system in accordance with the specified SEMI standard using a wafer handling system so that the substrates can be processed in a protected atmosphere within the factory by a process step. In the course of this, the process and system parameters should be continuously analyzed during production, statistically evaluated and emerging process problems detected and automatically and promptly displayed to the engineer or operator with suggested solutions. The cooperation between the system control software and the wafer transport system must correspond to the conditions within semiconductor production and, like all other relevant parameters, be analyzed and evaluated with a time resolution of 10 ms so that machine failures can be avoided and productivity increased in the long term.

Keywords: automation,ald,peald,plasma,atomic layer deposition,semiconductor equipment,production technology,process engineering,semiconductors,thin films,solid state materials,