Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
CIVITAS DESTINATIONS (DESTINATIONS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Innovation actions
Countries involved: Spain,Spain,Spain,Italy,Italy,Germany,Germany,Spain,Cyprus,Malta,Greece,China,Romania,Greece,France,France,Portugal,United Kingdom
Call: Demonstrating and testing innovative solutions for cleaner and better urban transport and mobility (H2020-MG-2015_TwoStages, 2015)
Start date: 2016-09-01
End date: 2021-05-31
Duration (months): 57.0
Total project cost (EUR): 20226055.74
EU funding (EUR): 17874948.01
Participants: 34
Project status: CLOSED

Within the EU, and particularly following the economic crisis; tourism will be, the ‘engine for economic growth’, particularly in the underperforming Mediterranean economies; where tourism has traditionally been a dominant economic sector. The world market of tourists continues to grow and Europe has unique selling points for further tourist growth from within and outside the EU (including China). The competitive market for tourism means that cities have to provide the high quality, sustainable environments desired by tourists, while providing local sustainable employment opportunities that overcome the seasonal and sometimes informal nature of tourist economies. Achieving sustainable mobility is a vital part of the growth equation for Europe’s tourist cities.DESTINATIONS will develop an innovative holistic approach to building sustainable urban mobility systems for both residents and tourists. The project impacts will make a positive contribution to demonstrating how this can achieve growth and therefore provide a benchmark for other EU tourist cities. DESTINATIONS will demonstrate and evaluate the effectiveness of innovative sustainable mobility solutions in 6 tourist cities with different characteristics but sharing common challenges. The solutions will address: • Sustainable Urban Mobility Planning for residents and visitors • Safe, attractive and accessible public spaces for all generations • Shared mobility and e-infrastructures towards zero emissions transport • Smart & clean urban freight logistics at tourist destinations • Mobility management & awareness for sustainable mobility • Attractive, clean, accessible and efficient public transport Achieving the objectives will increase the attractiveness of the city, both for tourists and for businesses in the sector and multiplier impacts in the economy for goods and services. All of these will contribute to better social cohesion (which attracts further investment). So sustainable mobility grows the economy.

Keywords: tourism mobility,shared economy,business models,data gathering,sustainable growth,quality of life,safety,public private partnerships,participation
Anticipatory Networking Techniques in 5G and Beyond (ACT5G)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Germany,Sweden,United States
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-05-01
End date: 2019-08-31
Duration (months): 52.0
Total project cost (EUR): 1043441.28
EU funding (EUR): 1043441.28
Participants: 5
Project status: CLOSED

The rapid growth in mobile network data traffic contributed to the unprecedented speed of 4G LTE adoption, creating the need of sustainable capacity growth in next generation of wireless systems, namely 5G. A key success factor of 5G is network and management system design for flexibility by prediction and adaptation. To this end, anticipation is a promising new approach. By predicting and adapting to upcoming events at various time scales, an anticipatory network improving the operation quality and efficiency. First, network resources ranging from spectrum and buffers can be managed optimally to meet users’ requirements. Second, network operators can jointly plan how to share infrastructures and resources to meet their demands at lower costs and better energy efficiency. The ACT5G project addresses these challenges by two parallel research thrusts which we identify as Network Prediction and Reaction Mechanisms. The research in these thrusts ranges from analytic methods and models for anticipatory networks, to optimization in resource management and infrastructure sharing. To achieve the objectives, ACT5G engages in a four-year research program centered around four industrial PhDs. Half of the duration of the involvement of the early stage researchers (ESRs) in the program will be spent at the site of Alcatel Lucent Bell-Labs, giving the core industrial aspect of the ACT5G project. ACT5G brings together a consortium of complementary research skills, ensuring that the involved ESRs conduct top-level beyond-state-of-the-art research, while enjoying a well-structured program for industrial-oriented doctoral studies. The added value of ACT5G is the creation of a critical mass of trained researchers, working together under joint industrial/academic supervision. The outcomes of the project are have a direct impact on the evolution towards 5G networks, the career perspectives of the ESRs, and the human capital of the European Research Area.

Keywords: anticipatory networking,infrastructure sharing,resource management,wireless networks
Disputing Medicine: Medical Dissertations at the Academy of Turku (1640–1828) (MedDis)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-01
End date: 2023-12-31
Duration (months): 24.0
Total project cost (EUR): 186167.04
EU funding (EUR): 186167.04
Participants: 1
Project status: SIGNED

The early modern period witnessed the gradual emergence of the unified field known today as science. The primary linguistic medium of all educated communication was Latin. Accordingly, Latin played a crucial role in how new scientific ideas were advanced and transmitted in (early) modern Europe. One of the most central – yet most neglected – literary forms employed to this end was the dissertation. Over the course of the 17th and 18th centuries, what was originally a collection of orally defended theses evolved into a self-sufficient piece of research. However, this transformation still lacks a systematic diachronic analysis and seems to be understood only broadly. Focusing on a corpus of medical dissertations published at the Royal Academy of Turku (Finland) between 1640 and 1828, MedDis action aims to provide a more comprehensive understanding of this crucial process in the history of Western science. To this end, the ER will first transcribe the corpus into an easily searchable database with the aid of Trankribus software; second, he will examine the history of medical education at the Academy of Turku; and, third, he will investigate the evolution of the genre at the Academy of Turku in its wider European context. Combining digital tools with more traditional philological methods, the action will yield completely new information on how the dissertation transformed from its early modern to its modern form and function. The ER has expertise in Neo-Latin, intellectual history and digital humanities. The action will take place at the Department of Classical Philology and Neo-Latin Studies at the University of Innsbruck. Home to the ERC project 'Nova Scientia: Early Modern Scientific Literature and Latin' (NOSCEMUS) and the Ludwig Boltzmann Institute for Neo-Latin studies, the host institution is the best place in the world to carry out this action. The knowledge and training received during this action will contribute significantly to the ER’s career prospects.
Synthetic biology-guided engineering of Pseudomonas putida for biofluorination (SinFonia)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Biotechnology
Action type: Research and Innovation actions
Countries involved: Estonia,Germany,Spain,Italy,Austria,Ireland,Germany,France,Czechia,Netherlands,United Kingdom,Luxembourg,Denmark
Call: Synthetic biology to expand diversity of nature's chemical production (RIA) (H2020-NMBP-BIO-2018-two-stage, 2018)
Start date: 2019-01-01
End date: 2023-08-31
Duration (months): 56.0
Total project cost (EUR): 7948503.48
EU funding (EUR): 7948503.48
Participants: 13
Project status: SIGNED

Nature has hardly evolved biochemical reactions involving fluorine (F), the most abundant halogen on Earth. Organic compounds containing F (fluorochemicals) are, however, extremely relevant from an industrial point of view. Fluoropolymers are the main fluorochemicals in the market worldwide, and are exclusively synthesized using chemical methods. Moreover, current fluorination technologies usually involve corrosive and toxic reagents that have a negative impact on the environment. Designing sustainable bioprocesses based on alternative and safer fluorinating agents from renewable substrates is thus a long-sought-after, yet unfulfilled goal. SinFonia proposes to engineer the metabolically-versatile bacterium Pseudomonas putida to execute biofluorinations for generating novel fluoropolymers from renewable substrates. P. putida KT2440, a non-pathogenic soil bacterium, serves as an ideal microbial platform for F-dependent biochemical reactions due to its extraordinary resistance to harsh and stressful operating conditions. SinFonia will exploit natural selection to enhance bioproduction through a smart strain engineering approach in which bacterial growth will be coupled to biofluorination. Our target compounds are a whole family of fluorinated polyesters with enhanced physicochemical and material properties, with uses as self-cleaning surfaces, low-surface-energy coatings, bio-based lubricants, membranes for fuel cells, and anti-fouling materials. The versatile P. putida strains engineered during the project can be easily adapted to synthesize other added-value fluorochemicals. Unlike chemical processes, the source of F in our system will be NaF, an inexpensive and safe salt, and sugars as the main carbon source. In-depth analysis of all the environmental and economic benefits of the new fluorination technology, and interactive communication of social benefits associated with target products, are essential components of SinFonia.

Keywords: synthetic biology,metabolic engineering,pseudomonas putida,fluorination
What can digital communications do for generational renewal in farming? (YOUNG FARMERS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,United States
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-07-01
End date: 2024-06-30
Duration (months): 36.0
Total project cost (EUR): 264669.12
EU funding (EUR): 264669.12
Participants: 2
Project status: SIGNED

A global difficulty of attracting youth into farming, and the growing pressure on institutions to respond to the demand for efficient knowledge-transfer to youth in the digital age, are two key challenges within the contemporary socio-economic research. The YOUNG FARMERS project addresses these challenges by exploring the important but poorly explored question of how the global needs of youth in farming can benefit from digital communication technologies. There is already increasing use of digital communication tools by institutions to support generational renewal in farms such as establishing online youth forums, supporting digital farming platforms, using social media to disseminate information, and mobilize youth. However, these tools are still relatively new, thus it remains unclear as to how exactly they may contribute to generational renewal. The YOUNG FARMERS project aims to explore this digital communication transformation to develop a new thinking that guides generational renewal policies with a cross-national study in the USA and in Germany. At the center of the digital communication concept is the “networked individualism” model, which has been developed by digital sociology field to understand behavior patterns. Project conduct a study on the “networked” nature of youths’ economic behavior with focus on youth engagement into farming as a “career option”. The project is innovative, as it provides new perspectives to structure public debates in the area of rural youth, agricultural policies, and digital government. This project contributes (1) to the rise in new knowledge-transfer initiatives (e.g. EU young farmers’ networks, Erasmus+ apprenticeships in agriculture) that intend to offer new communication approaches to promote European young farming talents, and (2) to support the development of the human capital dimension of the Common Agricultural Policy post-2020, which has identified generational renewal as one of its nine goals.

Keywords: generational renewal in farming,digital communication,youth labour market behavior,comparative study
5G-enabled Growth in Vertical Industries (5GROWTH)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Italy,Germany,Germany,Italy,Italy,Spain,Spain,Spain,Greece,Belgium,Poland,United Kingdom,Portugal,Portugal,Portugal
Call: Advanced 5G validation trials across multiple vertical industries (H2020-ICT-2018-3, 2018)
Start date: 2019-06-01
End date: 2022-02-28
Duration (months): 33.0
Total project cost (EUR): 14109226.25
EU funding (EUR): 14109226.25
Participants: 25
Project status: CLOSED

The vision of the 5Growth project is to empower verticals industries such as Industry 4.0, Transportation, and Energy with an AI-driven Automated and Sharable 5G End-to-End Solution that will allow these industries to achieve simultaneously their respective key performance targets. Towards this vision, 5Growth will automate the process for supporting diverse industry verticals through (i) a vertical portal in charge of interfacing verticals with the 5G End-to-End platforms, receiving their service requests and building the respective network slices on top, (ii) closed-loop automation and SLA control for vertical services lifecycle management and (iii) AI-driven end-to-end network solutions to jointly optimize Access, Transport, Core and Cloud, Edge and Fog resources, across multiple technologies and domains. The main objective of 5Growth is the technical and business validation of 5G technologies from the verticals’ points of view, following a field-trial-based approach on vertical sites (TRL 6-7). Multiple use cases of vertical industries (Comau, Efacec_S, Efacec_E, Innovalia) will be field-trialed on four vertical-owned sites in close collaboration with the vendors (Ericsson, Interdigital, NEC, Nokia) and the operators (Altice, Telecom Italia, Telefonica) in the project. 5Growth will leverage on the results of 5G-PPP Phase 2 projects where slicing, virtualization and multi-domain solutions for the creation and provisioning of vertical services are being developed and validated, e.g. 5G-TRANSFORMER and 5G-MONARCH. Two ICT-17-2018 5G End-to-End platforms, 5G EVE and 5G-VINNI, have been selected for the Trials to demonstrate the 5Growth specific vertical use cases. In addition to the impact on vertical-oriented standards (e.g., EN50126 (IEC62278) for railway signaling), the verticals in the consortium will be offered an opportunity to influence ongoing 5G standardization by leveraging the involvement of leading experts in the various relevant SDOs.

Keywords: vertical industries,network slicing,multi domain orchestration,closed sla loop,business validation,5g ppp,field trials,network,function virtualization,management and orchestration
Mapping the impact of the Augustan colonies on the Early Roman Empire (IMPACTVM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: SIGNED

The main purpose of the IMPACTVM project is to evaluate the socio-political impact of Augustan veteran colonies (1st c. BC – 1st c. AD) by understanding of how Latin and epigraphy was spread in local communities across the Roman world. This will allow us to understand the colonisation process, the origin of the colonists, the foundational policy of urban and sub-urban power centres, and the effectiveness of the Augustan colonisation’s impact on the creation of the Roman Empire through 5 selected study cases. The project has a strong multidisciplinary nature involving a combination of well-developed approaches to Roman colonisation (epigraphy socio-linguistic approach; GIS; network analysis; historical approach; quantitative analysis; etc.) for reformulating the methodology in the studies of historical colonisation. This proposal includes both the transfer of knowledge to the host institution and the training of the candidate in new advanced techniques (Digital Humanities) and methodologies. The result of this research will not only be papers, two seminars (in Athens and Rome), the publication of the proceedings and the collective manual on ancient names, but it will also be made available to the general public through some activities, as well as a booklet and a dissemination paper in an informative newsstand journal. This fellowship will be undertaken at the Dipartimento di Scienze dell’Antichità of the Sapienza Università di Roma under the mentorship of Gian L. Gregori with two secondments, first in the Universities of Oxford/Nottingham under the supervision of Alex Mullen and the second in the National Hellenic Research Foundation of Athens under the supervision of Sophia Zoumbakis. The project is in line with the EU strategy of promoting cultural heritage and identity, the diversity of European culture, the interaction and translation of the traditions of its different countries and regions, and cultural cooperation with third and developing countries.

Keywords: epigraphy,numismatics
Environmental modulators of the immune cell balance in health and disease (ENVIROIMMUNE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Germany,Belgium
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-08-01
End date: 2020-07-31
Duration (months): 60.0
Total project cost (EUR): 1499041.0
EU funding (EUR): 1499041.0
Participants: 2
Project status: CLOSED

The incidence of autoimmune diseases in developed societies is increasing at high rates, but the underlying cause for this phenomenon has not been elucidated yet. Since the genetic architect remains considerably stable, this increase is likely associated with changes in the environment. Autoimmunity is linked to an imbalance of pro-inflammatory Th17 cells and anti-inflammatory Foxp3+ regulatory T cells (Treg). However, little is known regarding environmental factors that influence the Th17/Treg balance. We recently discovered that a sodium-rich diet severely exacerbates experimental autoimmune encephalomyelitis (EAE) through an increased induction of pathogenic Th17 cells. Surprisingly, our preliminary data indicate that high-salt conditions also significantly impair Treg function, resembling a phenotype observed in several human autoimmune diseases. In addition, we have evidence that a high-salt diet affects the gut microbiota, implicating possible indirect effects on immune cells in vivo. Based on these findings we hypothesize that excess dietary salt represents an environmental risk factor for autoimmune diseases by modulating the Th17/Treg balance by several direct and indirect mechanisms. To address this hypothesis we will 1) examine the underlying mechanisms of high-salt induced Treg dysfunction and effects on the Treg/Th17 balance by molecular and functional analysis in vitro and compare it to known risk variants of human autoimmune diseases, and 2) define direct and indirect effects of excess dietary salt on the Th17/Treg balance and autoimmunity in vivo and explore potential novel pathways for targeted interventions. Thus, the proposed study will uncover the impact of a newly discovered environmental modulator of the immune cell balance and will ultimately pave the way for new approaches in therapy and prevention of autoimmune diseases.

Keywords: autoimmunity
A reliable CXCL4 biomarker assay to improve diagnosis and treatment of Systemic Sclerosis (ASSYSt)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2018-08-01
End date: 2020-01-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Systemic Sclerosis (SSc, scleroderma) is a complex autoimmune disorder of unclear aetiology, culminating in excessive extracellular matrix deposition (fibrosis/tissue scarring) in skin and internal organs (e.g. joints, heart, lung, gastrointestinal tract and kidneys). More than half of the patients will ultimately die as a result of organ complications. The medical need is exacerbated by the lack of curative treatments and the lack of specific and sensitive molecular markers to facilitate reliable diagnosis and prognosis. My team has recently demonstrated, through research funded by the ERC Starting Grant CIRCUMVENT, that the chemokine CXCL4 is a central player in the pathogenesis of SSc. Our results suggest that CXCL4 has great potential as 1) a biomarker to assist early diagnosis, 2) a biomarker to predict SSc disease course, and 3) a therapeutic target for the treatment or prevention of fibrosis in patients with SSc. Currently, a robust, accessible, reliable, cheap and fast assay to determine CXCL4 levels for clinical use is lacking. This prohibits the use of CXCL4 to predict clinical and treatment outcome and complicates the large-scale replication experiments across multiple labs and cohorts that are necessary to validate the diagnostic value of CXCL4. Therefore, we argue that a reliable in vitro assay measuring circulating CXCL4 levels is highly needed and can be deployed as a research support tool to accelerate the implementation of clinical strategies based on CXCL4 and a clinical decision support tool in SSc to complement current diagnostic protocols. ASSYSt will focus on 1) the development of a reliable assay to adequately determine circulating CXCL4 levels irrespective of sample collection and storage conditions, 2) assessing the market potential of each of the applications listed above, and 3) defining a strong business strategy to guide route to market.

Keywords: systemic sclerosis,diagnostic test,commercial feasibility