Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Property, Power, and the Political State: Angevin Theologians in the 1322 Consultation on Apostolic Poverty (ProPPS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

The 1322 consultation launched by Pope John XXII on the theological doctrine of Apostolic Poverty is one of the most catalyst moments in European intellectual history, where a question of religious practice evolved and exploded into a question of property, power, and the political state. The MSCA-PF ProPPS is an interdisciplinary project that brings together theological doctrine, religious and political identities, and royal and papal politics within the canvass of the medieval intellectual, spiritual, and political life of the Angevin state and theologians. ProPPS will be the first attempt to map and analyse a collection of texts connected to the patronage of King Robert of Naples, to study the group Angevin theologians as part of an intellectual network within the poverty debate, and to situate the intellectual position of King Robert in his sacral-political symbiosis with the papacy. The project will shift current scholarly focus from the papal-imperial conflict to highlight the intellectual richness and diversity of the theological and philosophical treatises within a complex network of political and religious loyalties. ProPPS has three research objectives: (1) a doctrinal, philosophical, and philological study of a major treatise in the poverty debate by the trusted papal adviser Francis of Meyronnes, of his thoughts on property, social and economic power, and the nature of civil and political state, before proceeding to (2) a prosopographical and doctrinal study of the Angevin theologians and their contributions to the poverty controversy in 1322, on where they stand individually and collectively on the controversy, and finally (3) a macroscopic study of the court of Robert of Naples in its relationship with the Franciscans, the ecclesiastical hierarchy, and the papacy. The project will adopt methods of manuscript studies, conceptual and contextual analysis of selected texts, and document and archive analysis.

Keywords: poverty,franciscan,papacy,theology,philosophy,political thought,intellectual history,angevin,naples
Carbon-negative pressurized hydrogen production from waste using an energy efficient protonic membrane reformer CARMA-H2 (CARMA-H2)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Innovation actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: Spain,Norway,Denmark,Italy,Netherlands
Call: Waste to Hydrogen demonstration plant (HORIZON-JTI-CLEANH2-2023-1, 2023)
Start date: 2024-10-01
End date: 2028-09-30
Duration (months): 48.0
Total project cost (EUR): 12818293.75
EU funding (EUR): 9954418.76
Participants: 12
Project status: SIGNED

CARMA-H2 will enable highly attractive hydrogen production from biogas through demonstration of a protonic membrane reformer (bioPMR) that integrates steam methane reforming and water-gas shift reactions, hydrogen separation, heat management, CO2 capture and hydrogen compression in a single stage. The realization of 6 process steps in a single reactor allows to achieve unprecedented energy efficiency with a project target to demonstrate >85% (HHV) at the bioPMR level. The bioPMR technology enables direct delivery of purified and pressurized H2 (30 bar). BioPMR will be coupled with CO2 liquefaction to enable direct production of food-grade CO2. Coupling the liquefaction unit allows for higher hydrogen recovery and liquid CO2 production as the off-gas from the liquefaction process will be recycled back to the bioPMR unit. CARMA-H2 will demonstrate the bioPMR technology integrated with CO2 liquefaction at the existing Arazuri wastewater treatment plant in the region of Navarra in Spain. The demonstration plant will be operated for at least 4000 h, and produce 500 kg/day of hydrogen and above 4000 kg/day of food-grade CO2. To facilitate the demonstration CARMA-H2 will install 1) a pre-treatment system for biogas compression and removal of sulphur and other impurities, 2) two bioPMR modules which will operate directly on biogas (CO2 > 40 vol.%), and 3) an integrated CO2 liquefaction unit. The demonstration plant will be located in Ebro Valley Hydrogen Corridor, and the project aims to secure off-take of the produced hydrogen and liquid CO2 during operation. The overall system will be controlled and analysed by an advanced control system and an associated digital twin that will be developed in the project. The wastewater plant is currently operating a biogas production plant of >4 MW from which the biogas is utilized for power generation. The achievements in CARMA-H2 will be an important proof of technological feasibility advancing the technology from TRL5 to TRL7.

Keywords: carbon negative electrochemical hydrogen production demonstration plant proton conducting ceramics waste to hydrogen co2 capture and liquefaction carbon negative electrochemical hydrogen produc
Propelling the shift toward the future of circular, safe and sustainable packaging and single use device ecoDesigned solutions through healthcare environments (ENKORE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Innovative Health Initiative
Action type: Research and Innovation actions
Partnership: IHI (JU-JTI)
Countries involved: Spain,Germany,United States,Poland,Greece,Netherlands,Italy,Belgium,Bosnia and Herzegovina,France,Denmark,Switzerland,Luxembourg,United Kingdom,Ireland
Call: Safe & Sustainable by Design (SSbD) packaging and single use device solutions for healthcare products (HORIZON-JU-IHI-2023-04-two-stage, 2023)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 14541588.49
EU funding (EUR): 7742500.0
Participants: 52
Project status: SIGNED

The healthcare sector is hindered by several barriers that hamper the application of circular economy principles (e.g. the safety restrictions of the domain limit the use of recycled materials due to the need of materials biocompatibility, and safety in products to be used in the human body). Led by a multidisciplinary consortium of 39 partners (plus 13 industry affiliates) from 15 EU countries plus UK and USA, ENKORE aim to tackle challenges and develop an ecoDesign framework that supports the development of safe and environmental compliant devices eco-responsible packaging, which minimize the environmental impact, reduce the carbon footprint, and maximize the use and preservation of resources. The main goal is to connect the design of the medical devices packages with the end-of-life stage, thus the technologies that support circularity are taken into account at the medical device conception stage. ENKORE framework will be validated in 5 Reference Use Cases (RUCs), led by 5 different health regions that bring HPCs and policy maker, 3 large EU hospitals and the reference network for European Regional and Local Health Authorities (EUREGHA). The project developments and RUCs are supported by several associations and NGOs, a packaging manufacturer and a group of SMEs and researchers, specialists in circularity, LCA, social sciences, environment, circularity, and materials. The validation of the framework shall provide evidence to work with policymakers, creating new or revised standards and create tangible/quantitative evidence. Policy making and regulatory engagement will be strongly performed. The methods and tools comprise Environmental and Social Life Cycle Assessment (ELCA/SLCA), Circularity Calculator (CC) and Digital Product Passport (DPP) approaches, which could be adapted during the second stage of the proposal.

Keywords: safe and sustainable by design,ecodesign,circularity,recycling,lca,life cycle assesment
IDENTITY AND CONSENT MANAGEMENT FOR EU DIGITAL AND DATA STRATEGIES (CONSENTIS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Increased Cybersecurity
Action type: Innovation actions
Countries involved: Germany,Ireland,Greece,Romania,Spain,Cyprus,Italy,Netherlands,Switzerland
Call: Privacy-preserving and identity management technologies (HORIZON-CL3-2023-CS-01, 2023)
Start date: 2024-11-01
End date: 2027-10-31
Duration (months): 36.0
Total project cost (EUR): 5346555.16
EU funding (EUR): 3998855.36
Participants: 13
Project status: SIGNED

CONSENTIS is geared to alleviate the challenges posed by personal data sharing towards the implementation of EU regulations and strategic initiatives like eIDAS, EU Data Spaces and GDPR. It introduces a novel framework which offers Self-Sovereign Identity and user-centric consent management solutions that enables users to (a) have full control over their personal data collection and usage and (b) provide informed consent through user-friendly interfaces and notifications. The proposed framework is agnostic to existing services and formats and guarantees high levels of protection avoiding potential legal uncertainty, through a continuous assessment mechanism for security, risk and legal aspects. CONSENTIS is an industry-oriented project, with SMEs and large companies covering more than 80% of the consortium and is built on a collaboration of 12 organisations from 9 EU member states and associated countries. The Consortium includes: 2 academic institutions, 8 SMEs and 2 large industry partners that bear strong interest and relevance to the project objectives and are highly committed in the delivery of scientific excellence and innovation in the fields of identity management and SSI, consent management, blockchain and smart contracts, user interfaces/user experience, cybersecurity and PETs, business and market impact and EU laws, policies and regulations for human rights and technology.

Keywords: identity management,self sovereign identity,informed consent,security,privacy,blockchains,data economy
Magnetic Resonance at the Scale of a Cell (HYPERCELL)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Challenges
Action type: EIC actions
Countries involved: Germany,Switzerland
Call: EIC Transition Challenge: Full scale Micro-Nano-Bio devices for medical and medical research applications (HORIZON-EIC-2023-TRANSITION-01, 2023)
Start date: 2024-04-01
End date: 2026-09-30
Duration (months): 30.0
Total project cost (EUR): 1998750.0
EU funding (EUR): 1998750.0
Participants: 2
Project status: SIGNED

The HyperCell project merges two groundbreaking technologies to validate a benchtop tool for cell metabolic analysis, promising to revolutionize cell research. It empowers researchers to explore individual cell metabolic profiles, unveiling hidden disease mechanisms, understanding organism development, and revealing treatment responses. This innovation fills a crucial gap in the field, as current methods struggle to provide reliable metabolic data at the micro to picolitre scale. HyperCell's standout feature is its non-invasive approach to deliver quantitative metabolic information at the single-cell level without disrupting cell metabolism. This unique capability positions ANNAIDA and NVISION as global leaders in NMR technology, offering an unmatched solution in the market. The initial application for this technology is embryo analysis, addressing infertility, a widespread issue affecting one in six couples globally. The project will focus on the optimization, integration and validation of NVISION's Quantum-Based Platform, which Enhances NMR spectrometers' sensitivity to metabolites via hyperpolarization, enabling real-time monitoring of intracellular metabolic activity, with ANNAIDA’s Embryospin Sensor Technology Tailored for microscale NMR.

Keywords: single cell metabolic analysis,micro nmr,ivf,embryo analysis,hyperpolarization
The rhythms of our mind. A mechanistic model of how oscillating body-brain states structure human cognition (FLOW)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Netherlands
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2025-10-01
End date: 2030-09-30
Duration (months): 60.0
Total project cost (EUR): 2499692.0
EU funding (EUR): 2499692.0
Participants: 1
Project status: SIGNED

We live in a rhythmic world. Take a deep breath, listen to your heartbeat, to the trees swinging with the wind, music playing, people chatting. Every perception and cognition, every heartbeat happens in time following its own rhythmic frequency. Our brain also generates rhythmic brain waves and there is wide consensus that these neural oscillations are a fundamental building block of how our brain works. Interestingly, the brain is not the only organ generating such intrinsic rhythmic signals. Bodily rhythms such as heartbeats, breathing or gastrointestinal activity can also be described as endogenous oscillators. But are these brain and bodily rhythms functionally relevant for how we perceive the world? Could it be that these rhythms determine what we attend to, what we remember and how much information we can store in our mind? This ERC proposes a new perspective on how oscillating body-brain states structure our cognition. We hypothesize that brain rhythms enable us to adapt to changing cognitive demands by flexibly switching between two fundamental operating modes: (i) to support communication between brain regions (WP1), and (ii) to code for the mental representation of specific content in our mind (WP2). We further propose that bodily rhythms can also dynamically tune their coupling strength with the brain in a state-dependent manner (WP3), supporting the operating mode of neural oscillations when being in “flow” (WP4). We formalize these hypotheses in a proposed FLexible Oscillatory Workspace (FLOW) model and empirically test our predictions using a noninvasive “brain pinging” approach for causally probing state-dependent rhythmic body-brain coupling mechanisms. In a final proof-of-principle project, we will then use rhythmic non-invasive neuromodulation for entraining and tuning intrinsic brain and body-brain rhythms to enhance cognitive performance and develop new rhythmic neuromodulation therapies to treat cognitive deficits (WP5).

Keywords: brain rhythms,neural oscillations,cognition,brain stimulation,neuromodulation
DEVELOPING FAST AND RELIABLE AUTOMATED DENT INSPECTIONS FOR AIRCRAFT MAINTENANCE​ (I3DM)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 36.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Donecle aims to revolutionize aircraft maintenance with automated drone inspections. With a growing air traffic market and labor shortages, optimizing maintenance efficiency is crucial. Our project, "I3DM," seeks to address these labor shortages, by optimizing maintenance efficiency and enhancing safety. Donecle's Iris 3D Mapping drone, with its fully automated flight and precise damage detection, reduces inspection times from hours to minutes, enabling faster aircraft turnaround and reduced AOG costs. The project's objectives are threefold: 1) Technological Innovation: Further develop and validate the Iris drone's automated flight, obstacle avoidance, and precise damage detection and surface deformations such as dents, achieving TRL 9; 2) Regulatory Compliance: Obtain necessary approvals and certifications for commercial deployment, addressing potential delays in regulatory approvals; 3) Market Penetration: Expand geographically, targeting key aviation markets, and ensuring worldwide adoption of the solution by airlines, MROs, and manufacturers. We will achieve these objectives through extensive testing, collaboration with industry stakeholders, and strategic market expansion. The final solution, including drone, software, and data hosting, optimizes maintenance processes, improves safety, and provides actionable data insights. The solution can be extended to other applications, such as ships and wind turbines inspection. Our strong established IP, with patents already filed in several countries, and our experienced team ensure the project's success. The project's estimated costs are €3.5M, with a requested grant of €2.5M. The EIC Accelerator funding will be crucial for Donecle to bring this innovative solution to market, outcompete rivals, and drive industry-wide adoption.

Keywords: drone,aircraft,dents,automated inspections,maintenance,3d mapping
Fluently - the essence of human-robot interaction (Fluently)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Innovation actions
Partnership: AI-DATA-ROBOTICS, Made in Europe (co-programmed)
Countries involved: Germany,Italy,Japan,Malta,Netherlands,Denmark,Switzerland,United Kingdom,Spain,Greece,Poland,Sweden
Call: AI enhanced robotics systems for smart manufacturing (AI, Data and Robotics - Made in Europe Partnerships) (IA) (HORIZON-CL4-2021-TWIN-TRANSITION-01, 2021)
Start date: 2022-06-01
End date: 2025-05-31
Duration (months): 36.0
Total project cost (EUR): 11200141.55
EU funding (EUR): 9176043.5
Participants: 23
Project status: SIGNED

Fluently leverages the latest advancements in AI-driven decision-making process to achieve true social collaboration between humans and machines while matching extremely dynamic manufacturing contexts. The project results will be: 1) Fluently Smart Interface unit and 2) the Robo-Gym. The Fluently Smart Interface unit features: 1) interpretation of speech content, speech tone and gestures, automatically translated into robot instructions, making industrial robots accessible to any skill profile; 2) assessment of the operator’s state through a dedicated sensors’ infrastructure that complements a persistent context awareness to enrich an AI-based behavioural framework in charge of triggering the generation of specific robot strategies; 3) modelling products and production changes in a way they could be recognized, interpreted and matched by robots in cooperation with humans. Robots equipped with Fluently will constantly embrace humans’ physical and cognitive loads, but will also learn and build experience with their human teammates to establish a manufacturing practise relying upon quality and wellbeing. The bond between human and robot is personalized, and it is established during a preliminary training at the Robo-Gym, the first European hub for human-robot interactive training, where human and robot learn from each other a common work practice. Fluently will be validated by demonstration on three full scale pilots characterized by various level of automation, production dynamism and complexity of the manufacturing decision making process. The total project value required to commercialize the Fluently device and Robo-Gym concept is 18.8 M EUR. Forecast for EBITDA in 2028 is 16.3 M EUR, payback in 2028, with 13% gross profit and ROI 91% in line with sectorial performances. The new turnover generated requires at least 325 workers employed along the Fluently supply chain. Fluently will bring together 21 key industrial and academic stakeholders from 13 countries.

Keywords: asic based smart interface unit,artificial intelligence empathy,enhanced human collaboration,zero coding
Organ and mutation dependencies shaping the tumor microenvironment (BrcaSCope)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Israel
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Tumors are ecosystems in which cancer cells interact with diverse cell populations. In each such ecosystem, environmental conditions, cellular compositions and paracrine signaling create a distinct tumor habitat. How much the composition of the habitat is dictated by the organ versus specific mutations in the cancer cells is unknown. If different organs and mutations have common microenvironmental design principles, one could devise more general therapy. Otherwise, therapy must be mutation and organ specific. To approach this, we will focus on major cancer mutations – in BRCA1/2 – and on the four organs where BRCA mutations drive cancer: breast, ovary, pancreas and prostate. We will dissect microenvironments of BRCA-driven cancers in these organs using a wide arsenal of imaging, sequencing, and molecular tools, building on our recent discovery of distinct cancer-associated fibroblast (CAF) compositions in BRCA-mutated breast cancer. To untangle complexity, we will establish a new approach to calibrate mathematical models on ex-vivo cocultures, and use it to identify testable targets. First, we will define the configuration of CAF subsets in the four organs, comparing BRCA-mutated to BRCA-WT human tumors (Aim 1). To unravel signaling loops common and different between organs, we will explore fibroblast dynamics in normal tissues and their diseased counterparts by ex-vivo cocultures and mathematical modeling (Aim 2). We will leverage this knowledge to design CAF inhibitors and combine them with BRCA-specific therapies in cocultures and preclinical models, to address a major unmet clinical need to exploit CAF vulnerabilities for cancer therapy (Aim 3). This program provides a conceptual paradigm for understanding the principles of tumor microenvironment habitats, using BRCA as a testcase and four organs of clinical interest as model systems. This paradigm will be directly applicable to the major mutation classes and organ environments of cancer.

Keywords: tumor microenvironment,cancer associated fibroblasts,tumor heterogeneity,extracellular matrix,brca1 2,multiplexed immunofluorescent imaging,image analysis,breast cancer,ovarian cancer,pancreatic cancer,prostate cancer,single cell rna sequencing,transcriptional profiling,cancer therapy,parp inhibitors