Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Short-wave Infrared Light emitters based on Colloidal Quantum Dot Technology (SWIRL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-09-01
End date: 2024-02-29
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Optical sensing and imaging has evolved from taking digital images to a powerful metrology, imaging and data acquisition technique by expanding the spectral coverage from the visible to the short-wave infrared (SWIR). SWIR sensing and imaging is the cornerstone of advanced imaging techniques for 3D visualization, night vision, imaging though adverse weather conditions, biomedical imaging, spectroscopy for food quality and health monitoring, just to name a few. The huge market size of such applications, especially by entering volume markets including consumer electronics and automotive, has led to the first commercial appearances of low cost CMOS compatible SWIR photodetectors and image sensors. Yet for the realization of the afore-mentioned technologies the optical source is an equally important and crucial component to be considered at system level. To date, there is a lack of infrared optical sources that are CMOS compatible, low-cost with competitive performance over the standard costly epitaxial III-V light emitters. Moreover high cost and epitaxial growth manufacturing processes have limited the size and form factor of those sources to small and rigid elements preventing their use as high power and large area illumination sources. SWIRL will undertake this challenge to develop high performance low-cost SWIR optical sources with tunable emission peaks and spectral bandwidths across the eye-safety SWIR window, exploiting colloidal quantum dot technology. By leveraging engineering at the nanoscale and solution processed materials we will develop in TRL4/5 SWIR optical emitters that are low-cost, high efficiency, even rivalling their epitaxial counterparts, and spectrally versatile across the SWIR. We will further demonstrate their use in key applications related to automotive industry as optical sources for active SWIR imaging and in-cabin monitoring in the eye-safety infrared window.
ELectrochemical OXidation of cYclic and biogenic substrates for high efficiency production of organic CHEMicals (ELOXYCHEM)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Processes4Planet (co-programmed)
Countries involved: Norway,Germany,Spain,Italy,United Kingdom,Greece
Call: Energy efficiency breakthroughs in the process industries (Processes4Planet partnership) (RIA) (HORIZON-CL4-2023-TWIN-TRANSITION-01, 2023)
Start date: 2024-01-01
End date: 2028-06-30
Duration (months): 54.0
Total project cost (EUR): 10778699.59
EU funding (EUR): 9257523.19
Participants: 11
Project status: SIGNED

ELOXYCHEM will establish a commercially relevant electrochemical oxidation process that will become a strategic development to replace existing chemical conversion processes that are heavily reliant on imported materials such as nitric acid and imported fossil-fuels such as natural gas. ELOXYCHEM will promote a credible pathway for Europe’s twin transition (green and digital) by demonstrating: (i) a new transformational electrochemical conversion platform process at a pilot scale (multiple tonnes per annum) consisting of reactors and downstream separation to final products with marketable specification to reliably achieve TRL6; (ii)drop-in replacement technology for chemical conversion. ELOXYCHEM will also optimise the process to demonstrate versatility of the process to multiple feedstocks ranging from current feedstocks and future bio-based and biogenic sources. Using AI strategies for optimisation the pilot plant will be targeted improve electrochemical performance, improve lifetime and reduce cost; prove viability of integrating with renewable energy sources considering intermittency and potential to offer demand-response flexibility; integrate process design, including materials, reactor/cell, and separation methods, from the process intensification and cost perspectives. ELOXYCHEM brings together a world-leading consortium consisting of chemical/bulk material producers, manufacturers, and universities from across Europe to addresses the expected outcomes and achieve energy consumption savings of ~60% compared with existing processes, ELOXYCHEM´s disruptive approach will help chemical industries transform their production process to reduce waste, use of harmful precursor chemicals, and become less energy intensive.

Keywords: electrochemical oxidation,ddda,digital control,renewable energy sources,energy,unsaturated fatty acids,pilot plant
GreenDEMO (GreenDEMO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Democracy and Governance
Action type: Research and Innovation actions
Countries involved: Germany,Austria,United Kingdom,Spain,Poland,Denmark,Belgium
Call: The role and functioning of public administrations in democratic systems (HORIZON-CL2-2024-DEMOCRACY-01, 2024)
Start date: 2025-01-01
End date: 2027-12-31
Duration (months): 36.0
Total project cost (EUR): 2999995.0
EU funding (EUR): 2999995.0
Participants: 14
Project status: SIGNED

GreenDEMO sets out to study the new and innovative role of public administrations in coping with societal challenges, particularly in supporting democratic processes of societal change to reach green sustainability goals. The project aims to contribute to 'greener' democracies in Europe and to more democratic sustainability transition processes. GreenDEMO more particularly proposes to design, prototype, test and replicate organisational innovation in city administration in order to enable, stabilise and enhance capacities of public administration to act for climate neutrality and democratic stability. City administrations need to collaborate with stakeholders to set up local green deals. This is critical given that trust in public institutions is weakening (crisis of democracies). Moreover, even in a less challenging political climate, establishing effective political interventions in support of ambitious climate and green sustainability goals is a complex issue. Thus, there is a double pressure on democracies to secure effectiveness and democratic legitimacy. Current studies suggest that this requires public administration to build up "transformative capacities". One lever to build such capacities is organisational innovation, e.g. new structures or processes, or practices. Demo Cities (Mannheim, Bristol, Aalborg) commit to such organisational innovation and will work on demonstrators, while Fellow Cities (Glasgow, Aarhus, Bamberg, Schaerbeek, Poznan) will work on replication activities and roadmaps for their own organisational change process. We assume that cities, which prove to be able to innovate their approaches and work together with their stakeholders, will be in a better position to implement (effective) local green deals. This, in turn, is expected to increase trust in public bodies and hence might be an important mechanism to strengthen democracies.

Keywords: organisational innovation demonstration replication green and democratic transitions in cities transformative capacities of public administration community of practice,organisational learning
Functional Nano-Scaffolds for Regenerative Medicine (NANOREMEDI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy,Spain,Israel,Switzerland,France
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 3413325.6
EU funding (EUR): 3413325.6
Participants: 19
Project status: SIGNED

Repair or replacement of tissue and organ functions lost due to age, disease or damage represents one of the most urgent medical needs of our aging society. The NanoReMedi Consortium will contribute to addressing this fundamentally important issue by using a new and efficient scientific approach relying on the design, preparation, characterization and validation of conceptually innovative peptide-based functional nanomaterials for regenerative medicine applications. Specifically, NanoReMedi will tackle three highly relevant case studies: “Tissue engineered vascular grafts to replace damaged peripheral arteries”, “Stem-cell based regenerative medicine for bone and cartilage repair” and “Facing with implantation failure” this last addressed to overcome bacterial severe infections. As an equally important goal, the NanoReMedi Consortium aims to build a world-class doctoral educational model in the field of nanomaterials applied to regenerative nanomedicine, through a strategically designed Academia-Industry interplay. To this end, 6 Beneficiaries, one Associated Partner linked to a beneficiary and 12 non-academic associated partners will join their forces to: i)create a highly innovative research network for training a new generation of 13 Doctoral Candidates (DCs) with strong employment potential, aimed at studying and developing “Functional Nano-Scaffolds for Regenerative Medicine”; ii)establish a robust structure for long-term research cooperation between a pool of leading Universities and Enterprises, for broadening and strengthening the knowledge and skills of DCs accessing the nanoscience-area from adjacent disciplines (such as chemistry, material sciences and bioinformatics); iii)building a solid foundation for long-term European excellence in medical nanotechnology via dissemination of research/training outcomes - through cross-network secondments, Summer Schools workshops and transferable skills modules, and of the best practice generated by NanoReMedi.

Keywords: hydrogel,electrospinning,unnatural amino acids
Development of fully synthetic bio-inspired extracellular vesicles for regenerative wound healing (SYNERGY)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 202125.12
EU funding (EUR): 202125.12
Participants: 1
Project status: SIGNED

Wound care constitutes a growing clinical and economic burden, with the global market predicted to exceed €28.6B annually by the end of 2024. This represents a 71% increase in wound prevalence and a 48% increase in management cost in the last decade. Despite advances in our understanding of the cellular and molecular mechanisms involved in wound healing, the rapid growth of these markets alone underlines the need for new therapeutic approaches to address the growing incidence of chronic and non-healing wounds and the ongoing development of scar tissue and fibrosis -which increase the risk of severe complications, significantly impact patient quality of life, and extend the burden on healthcare systems. Extracellular vesicles (EVs) from mesenchymal stromal cells (MSCs) and MSC-like cells, have already been proven to significantly enhance wound healing and inhibit scar formation. Despite their potential, the inherent complexity, source-based variability of these cell-based therapies, as well as a lack of conclusive information regarding their mechanisms of action, has significantly impeded their clinical translation. This proposal outlines the characterization of natural EVs from both novel and established MSC sources; the identification of key biological and biophysical factors underpinning their potential to support wound healing and reduce fibrosis; and the application of this knowledge to design, optimize, and validate bio-inspired fully synthetic extracellular vesicles (fsEVs) as a novel treatment to improve clinical wound healing outcomes.

Keywords: synthetic biology,bio inspired,mesenchymal stem stromal cells,mscs,extracellular vesicles,wound healing,tissue regeneration,
Dependence Of NUcleosome Transactions on Sequence (DONUTS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Molecules of Life: B iological  Mechanisms , Structures  and Functions
Panel description: For all organisms : Molecular biology , biochemistry, structural biology, molecular biophysics , synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Sweden
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-11-01
End date: 2028-10-31
Duration (months): 60.0
Total project cost (EUR): 2137145.0
EU funding (EUR): 2137145.0
Participants: 1
Project status: SIGNED

Eukaryotic genomes are packaged into chromatin, which restricts access to the DNA. Key genomic processes therefore involve the rearrangement of chromatin by ATP-dependent chromatin remodelling enzymes (remodellers), which actively place and reorganise nucleosomes. The precise positioning of nucleosomes plays a crucial role in regulating transcription, replication, and DNA repair. DNA sequence impacts this nucleosome architecture by affecting the activity of remodellers. However, what mechanisms underlie this critical sequence dependence in remodelling remains unknown. Here, we propose to address this longstanding question based on the following rationale: the nucleosome represents a highly constrained substrate with many histone-DNA interactions. Remodeller action therefore involves multiple sequential catalytic cycles and a series of transient structural intermediates of the nucleosome. We hypothesise that the nature and stability of these intermediates determine the effects of DNA sequence on remodelling. Probing this hypothesis requires the direct observation of transient remodelling intermediates as a function of sequence at the genome scale, which cannot be achieved with currently existing methods. We aim to address this major challenge by developing a novel high-throughput platform that combines, for the first time, single-molecule measurements of complex dynamics with next-generation sequencing. This platform will enable the comprehensive profiling of sequence-dependent processes at the single-molecule level. We will leverage the platform in combination with molecular simulations and in vivo experiments to gain groundbreaking insights into the mechanisms of sequence-dependent remodelling and its role in the establishment of chromatin architecture. Ultimately, we expect to decipher how the dynamic landscape of nucleosome intermediates - encoded in the sequence wrapped around the histone core - impacts nucleosome function in vivo.

Keywords: single molecule,fret,chromatin,chromatin remodelling,nucleosome,molecular motors,genome scale,high throughput
A multiprocessor system on chip with in-memory neural processing unit (NeuroSoC)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Research and Innovation actions
Countries involved: Italy,France,Germany,Switzerland,United Kingdom,Greece,Ireland,Austria,Netherlands
Call: Ultra-low-power, secure processors for edge computing (RIA) (HORIZON-CL4-2021-DIGITAL-EMERGING-01, 2021)
Start date: 2022-09-01
End date: 2027-02-28
Duration (months): 54.0
Total project cost (EUR): 7952677.5
EU funding (EUR): 7952677.0
Participants: 14
Project status: SIGNED

Deployment of intelligence at the edge presents many challenges because devices need to be low-cost and, as such, they are often constrained in computing capacity, memory, and energy resources. These constraints are not compatible with the need for much more advanced AI algorithms calling for Mbytes of storage and tens of GOPS per inference and call for leaner edge AI algorithms. The current state of the art for (the few) edge-AI chips relies on low-cost process technologies at 90 or 40nm and in some cases up to 16nm, with power efficiency between 1-5 TOPS/w and power densities up to 1 TOPS/mm2. Recently several industrial projects and a few products have started to surface pursing neuromorphic and in memory computing, but none of these efforts have reached a level of maturity compatible with a mass volume production and cost, and, moreover the technology base they rely on is either not scalable to more advanced nodes (flash) or, targeting AI computing algorithms whose practical applications are yet to be fully proven (e.g., spiking). The NeuroSoC approach instead is to rely on a solid, mature, and qualified reliable Phase Change Memory technology to create an industrially proven path to go past the state of the art, as such, the NeuroSoC chip pre-product demonstration of the technology will be the first of his kind worldwide. NeuroSoC’s aim is to develop an advanced Multi-Processor System on Chip prototype in FD-SOI 28nm CMOS technology that tightly integrates an AIMC IMNPU unit, a local digital processing subsystem, and functional safe multiprocessor host subsystems based on an enhanced version of existing RISC-V microprocessor implementation, while covering IMNPU security aspects holistically to tackle the requirements of a wide set of edge-AI applications. The project will leverage STMicroelectronics’s unique high-density embedded PCM cell process technology being the denser and only such technology qualified and mature for embedded use in the industry world

Keywords: imc ai low power pcm
Investigation of Disruptive 2D/Silicon Technology for Hybrid Multispectral Photodetection (Multi GRAPH)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Israel
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 1998750.02
EU funding (EUR): 1998750.0
Participants: 2
Project status: SIGNED

My research ultimate goal is to develop novel approaches for multispectral detection in emerging 2D hybridsilicon technology and unify in one single technological platform high-performance photodetectors in all spectral bands from visible to mid-infrared. Theoretical and experimental methods will be applied to study new concepts and physical phenomena for broadband photodetection in integrated 2D/Silicon hybrids, aiming for innovative solutions, novel device architectures and disruptive technological development of multispectral photodetection systems-on-chip. A diversity of modern applications ranging from remote healthcare and environmental monitoring, gas sensing and hazard detection, food and water inspection to biosensing and automotive vision share similar urgent needs for high-performance, miniaturized and lightweight multispectral optical sensors monolithically integrated with low-cost and high-functionality silicon electronics. However, current semiconductor photodetectors technologies are mainly tailored and optimized to specific spectral bands. Their roadmaps have so far prevented the development of universal detectors that could simultaneously address multiple spectral domains. Thus, there is a pressing need for a radically new approach that could combine high-performance broadband photodetectors in all spectral bands in one single silicon-compatible technological platform. Graphene and 2D materials integration with silicon technology open an unprecedented opportunity to reach this goal, leveraging unique ultra-broadband absorption properties of graphene and diversity of 2D-family with mature silicon fabrication facilities for monolithically integrated, scalable and cost-effective multispectral imaging systems. The fundamental study, exploration, and technological development of novel 2D/Silicon multispectral PD technology beyond the state-of-the-art and increasing its potential impact on modern application domains is the core objective of the Proposal.

Keywords: multi spectral photodetectors,2d materials integration with silicon technology,graphene silicon broadband detectors,hybrid van der waals heterostructures
Super-HEART: a fault-tolerant and highly efficient energy hub with embedded short-term energy storage for high availability electric power delivery (Super-HEART)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Challenges
Action type: EIC actions
Countries involved: Germany,Ireland
Call: Energy Harvesting and Storage Technologies (HORIZON-EIC-2021-TRANSITION-CHALLENGES-01, 2021)
Start date: 2022-04-01
End date: 2025-03-31
Duration (months): 36.0
Total project cost (EUR): 2499267.0
EU funding (EUR): 2499267.0
Participants: 3
Project status: CLOSED

Power electronics (PE) is spreading through society, including in mission critical applications. However, PE devices are prone to failure, and high availability is usually ensured using redundancy - which is expensive and bulky. In the meantime, PE allows hybrid (AC & DC) electric distribution, which is key to integration of solar power and use of hydrogen as energy carrier. But loads can be affected by the limited dynamics of power sources like fuel cells and by disturbances carried by the network. With Super-HEART, we want to build an energy hub connecting power sources and load, and able to deliver uninterrupted power. To this end, we will develop a multi-port modular converter with fault ride-through capability. This will be ensured using fault-tolerance strategies already proved in the ERC PoC Project "U-HEART", improved by the integration of supercapacitors (SC) to allow using reliable and low-cost mechanical switches to isolate the faulty parts instead of semiconductor switches, leading to a significantly higher TRL. Super-HEART will use SC also for compensating disturbances and the low dynamics of hydrogen-based storage. But commercial SC have power and energy densities too low to be practically considered here. Therefore, previously developed high-performance and environment friendly SC will be further optimised in this project and embedded in the converter by optimal co-design. In parallel to the technological development, we will prepare the monetisation of the IP, comprising a market analysis, the development of solid business model and tech-to-market transition plan, and the search for clients and partners. Ultimately, a power converter with embedded SC with availability, power density, cost, and losses, 20% better than state-of-the-art will have been developed, with reduced environmental impact. It will be ready for qualification and have undergone field tests. Potential clients and partners for the development and distribution will have been found.

Keywords: fault tolerance,supercapacitor,power converter,uninterruptible power supply