Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Ultrahard Molecular Magnets Based on Heavy Transition Metals (UltraMolMag)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 1
Project status: SIGNED

Molecule-based magnets are crystalline materials that exhibit magnetic properties analogous to those observed in traditional permanent magnets, but they can also show unique desirable functionalities, including low density, mechanical softness and physical tunability. In particular, the use of organic radicals in combination with 3d metals has been demonstrated by the Host group of Dr. hab. Rodolphe Clérac to produce high-temperature molecular magnets. However, frameworks featuring cationic 4d and 5d metal nodes are significantly underrepresented in this field of research, despite the fact that they offer more diffused d orbitals and greater spin-orbit coupling. The combination of these characteristics with the strong magnetic coupling offered by the radical ligands should result in the creation of ultrahard magnets operating at room temperature. This would challenge the monopoly of rare-earth magnets, the production of which is dependent on the supply of precursors that must imported into the EU. Therefore, the main objective of the UltraMolMag project is to develop a suitable synthetic methodology for the preparation of metal-radical systems featuring 4d and 5d elements as cationic centers. Their incorporation into extended systems is a formidable challenge, however, they can be tamed by the chemical tuning of the coordination sphere. In this project inert metal centers will be activated by preparing precursor complexes with labile substituents. Conversely, the unwanted catalytic activity will be mitigated by binding metal ions in the form of pre-organized units. The ultimate aim is to develop porous magnets based on extended radical anions, which will for the first time enable control over magnetic hysteresis through guest adsorption at room temperature. The implementation of this project will result in the creation of a library of heavy transition metal precursors and the fellow will receive training in the characterization of target frameworks.

Keywords: molecular magnetism
Nature Based Smart Water Grids for Integrated water and drought management (WATERGRID)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Innovation actions
Countries involved: United Kingdom,Spain,Slovakia,Malta,Belgium,Netherlands,Germany,Austria,Romania,Luxembourg,Italy,France,Switzerland
Call: Demonstrating Nature-based Solutions for the sustainable management of water resources in a changing climate, with special attention to reducing the impacts of extreme droughts (HORIZON-CL6-2024-BIODIV-02, 2024)
Start date: 2025-09-01
End date: 2029-08-31
Duration (months): 48.0
Total project cost (EUR): 7945771.25
EU funding (EUR): 7549383.13
Participants: 22
Project status: SIGNED

WATERGRID’s objective is to develop and demonstrate the Smart Water Grid (SWG) concept for more climate resilient water management, particularly targeting extreme drought, but framed within Integrated Catchment Management, addressing the whole catchment in a holistic approach. The resource efficiency of Nature Based Solutions (NBS) previously established in eight sites will be analysed alongside the academic literature, forming an Evidence portfolio (Project Result 1 - PR1). Of these eight sites, five will be demonstrators, spread across the Atlantic, Continental, Mountain and Mediterranean biogeographical areas, with specific water scarcity challenges, NBS types and scales, in which 58 additional innovative and locally attuned NBS will be implemented to slow, move and actively store water for reuse as part of locally designed SWGs. Three validation sites will mainstream potential of the SWG approach and demonstrate replicability of the Project Results (PRs) that have been co-created and co-deployed with 138 stakeholders in a participatory approach. Protocols and standards will be developed, providing a step-by-step guide for the design, maintenance and operation of the SWG (PR2). A digital Platform (PR3) will display models of the catchment and a Design App will provide guidance to users on designing NBS into their SWGs. This Platform will be linked to a Monitoring programme (PR4) to display real time information via a Digital Twin to support long term maintenance of SWGs. An Operationalising toolkit (PR5) will create enabling social, governance and economic environments for sustainable SWGs. Finally, at least three Policy briefs (PR6) will display SWG benefits to various policies, from the EU to the local scale. By 2035, WATERGRID expects to increase by 20% the water available for usage to compensate scarcity, decreasing 7 types of water pollutants and saving 10.6M €/year through 37 SWGs across Europe.

Keywords: nature based solutions,biodiversity conservation,climate adaptation,drought,integrated catchment management,monitoring
Pioneering methods to unravel lactation insufficiency (LactIns-and-outs)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-04-01
End date: 2027-03-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Breastfeeding is important for infant and maternal health. However, 10-15% of breastfeeding women fail to produce enough milk, while 40-50% give up early because of perceived insufficiency. As a result, only a minority meet the WHO recommendation to exclusively breastfeed during the first six months. To address this public health challenge, two key questions need to be solved: What do nursing infants actually drink? And how is this milk transfer regulated by mammary physiology? My vision is to pioneer new, quantitative methods that allow to solve these fundamental questions. Building on my expertise in biophotonic innovations for neonatal care, I propose to develop non-invasive optical tools to quantify milk transfer in situ (WP1) and map the causes of lactation insufficiency from the largely unexplored perspective of mammary physiology (WP2). In WP1, the scientific challenge is to develop methods for inline monitoring of both the milk volume consumed and its varying composition during a breastfeed. I propose two novel optical methods based on light scattering by milk fat globules, building upon laser Doppler flowmetry (volumetric flow rate) and angular resolved light scattering spectroscopy (composition). The technological challenge is to integrate both methods into a safe, compact sensor prototype, engineered into a nipple shield. In WP2, I will translate the technology of Diffuse Optical Spectroscopic Imaging (DOSI) to lactation science. Here, the scientific challenge is to quantify mammary physiological parameters in real-time, using DOSI and my sensor from WP1 during live breastfeeds. In both WPs, I will use state-of-the-art (medical) ultrasound for validation. By engineering dedicated tools for lactation research, this project will enable a leap forward in the diagnosis, treatment and prevention of both actual and perceived lactation insufficiency. In turn, this will lead to better breastfeeding support and improved individual and public health outcomes.

Keywords: breastfeeding,optics,light tissue interaction,laser doppler,fluid dynamics
Monopsony Power and Inequality (MARKINDOWN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: Italy
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1859312.5
EU funding (EUR): 1859312.5
Participants: 1
Project status: SIGNED

What is the role played by monopsony (monopoly power in the demand for labor) in widening earning inequalities? Recent studies documented the pervasiveness of monopsony power in modern labor markets. Monopsonistic employers can cut wages without losing workers to competitors, pay labor below its productivity and hire fewer workers than in a competitive labor market. The equilibrium is inefficient as the surplus given by market power is lower than the surplus extracted from workers who are also exposed to excessive work injury risk. Monopsony contributes to explain declining labor shares of income, persistently high levels of workplace accidents, and limited disemployment effects of minimum wages. Much less is known about the role of monopsony in increasing earning inequality. This project aims at filling this gap by i) contributing to a better understanding of the sources of monopsony power and ii) assessing their relevance across different socio-economic groups. Monopsony power can be due to anticompetitive arrangements introduced often in a non-transparent way in labor contracts.Another source of monopsony power is lack of information on alternative job opportunities. Frictions in the matching of workers and vacancies may discourage risk averse workers when planning to quit the firm after wage cuts. Spatial mismatch in the allocation of jobs and quitters may increase monopsony power vis-à-vis workers having a stronger distaste for commuting. Some groups of workers may also have stronger cognitive biases when interpreting available information on outside opportunities. The three parts of the project will i) assess the incidence of anticompetitive arrangements in Europe, ii) estimate firm-level labor supply elasticities across different categories of workers, and iii) using survey and experimental methods, evaluate to what extent the heterogeneity among socio-economic groups of willingness to quit a low-paid job is related to lack of information or cognitive biases.

Keywords: monopsony
Setting the Scene. Developing a Policy Agency for Sustainable Forms of Media Tourism (SETS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-09-01
End date: 2024-02-29
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

This project focuses on media tourism: the phenomenon of people travelling to places associated with movies, television series and other forms of popular culture. Media tourism has gradually evolved into a multi-million-dollar industry, with far-reaching implications for the related locations, affecting their economy, environment and community. As a result, city governments increasingly seek strategies to manage both the positive and negative impacts of these often-capricious media and tourism flows. However, the extensive research data generated by the ERC project ?Words of Imagination? (WOI), which has been collected in multiple Western and non-Western cities (e.g., Kingston, Seoul, Mumbai, Rio de Janeiro and Edinburgh), confirms (1) the potential of new media tourism initiatives and (b) the need for (humanities) research-based knowledge and critical and holistic advice to develop effective policies for sustainable and inclusive media tourism. Therefore, our goal is to set up a world-leading policy development agency called Setting the Scene (SETS) that is focused on providing municipalities around the world with a set of products and services to develop their media tourism industry in an environmentally sustainable, socially responsible and culturally sensitive manner. While several agencies advising government departments on the industry exist, none of them adopt a critical and holistic (humanities) perspective and focus on the sustainability and inclusivity of media tourism. The ultimate goal of this PoC is to demonstrate the (financial) viability and (technical) feasibility of the envisioned policy development agency SETS in assisting city governments with the search for tailored research-based policies concerning sustainable and inclusive media tourism.
ChECMating cellular senescence by modulating the surrounding matrisome (ChECMate senescence)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1496867.5
EU funding (EUR): 1496867.5
Participants: 2
Project status: SIGNED

The increasing elderly population poses a dual challenge to the viability of both global health and our current welfare systems. One of the pivotal aspects of aging involves the accumulation of damaged cells, known as senescent cells, in organs. While these cells play a role in coordinating tissue repair whenever damage occurs, their aberrant accumulation disturbs normal tissue function, resulting in an unbearable burden that ultimately leads to aging. Understanding how these cells accumulate within the organism, a yet unresolved question, would offer invaluable insights into the aging process. We have recently reported that damaged cells rely on Integrins, a family of membrane proteins, to implement senescence over cell death, leading to their accumulation within injured tissues. Remarkably, Integrins are known as the major cellular receptors binding to the surrounding extracellular matrix (ECM). Considering these precedents, we aim to take a step further and investigate whether the composition and status of the ECM can influence the buildup of senescent cells by impacting the choice between senescence and cell death upon injury, a possibility not explored before. Here, we aim to assess whether certain ECM proteins might act as pro-senescence factors by desensitizing damaged cells to death, favoring survival and aberrant senescence instead. We will thoroughly characterize multiple cell culture and mouse models of senescence implementation following damage, aiming to unveil the mechanisms controlling this phenomenon. Leveraging these findings, we will modulate the occurrence of cell senescence through ECM reengineering in mice, seeking to establish a revolutionary approach to address aging and tissue fibrosis. In sum, by uncovering unsuspected links between the ECM status and cell senescence implementation, ChECMate senescence would signify a paradigm change that would enable an unprecedented strategy in targeting cellular senescence in detrimental scenarios.
Imaging The Topological Defects of Light-Induced Phases in Quantum Materials (KnotSeen)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed Matter Physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 2498960.0
EU funding (EUR): 2498960.0
Participants: 1
Project status: SIGNED

Quantum materials host many exotic and useful phases, and harnessing these states has spurred tremendous research effort. However, the full potential of quantum materials lies in the rich landscape of higher-energy hidden phases, those which are not thermally accessible. Ultrafast laser excitation has recently emerged as a way access these hidden phases, leading to the idea of re-writing material properties “on demand”, but these states usually only survive for hundreds of picoseconds. Thus a key outstanding question remains: how can we stabilize light-induced phases? One key mechanism which can stabilize a phase is topology. The ultrafast phase transitions induced by femtosecond laser pulses naturally lead to the generation of topological defects. These defects, which can only relax after propagating until they encounter another topological defect, could either offer a route to stabilizing light-induced phases or impede their formation, and have been invoked in both contexts to explain many observations. However, actually imaging these nanometer scale defects on the femtosecond to nanosecond timescales required for light-induced phases has not been possible, and so the role of topological defects in light-induced phases remains unclear. In KnotSeen I will perform the first real space imaging of topological defects in light-induced phases using coherent XUV imaging methods, which provide the necessary spatial, temporal, and spectral resolution to map topological defects at the nanoscale and out of equilibrium. I will map the creation, propagation, and destruction of topological defects in two important cases: quenched superconductivity in the cuprates and light-induced phases in the manganites. A novel data analysis approach will be used to distinguish repeatable from stochastic dynamics at the nanoscale. KnotSeen will reveal the mechanisms by which topological defects control light-induced phases, enabling new tools to stabilize and selectively control them.

Keywords: light induced phases,topological defects,ultrafast,coherent imaging,nano imaging,high harmonic generation,xuv,superconductivity
Making Old Objects Valuable Again. The Cultural, Economic Challenges and Sustainability Opportunities of Antiques in the 21st Century (MOOVA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1493339.0
EU funding (EUR): 1493339.0
Participants: 1
Project status: SIGNED

What do old porcelain, wooden furniture, and silverware have in common? All of these antiques fall into the category of informal heritage. Regardless of their cultural significance, many of these objects remain on the margins, both in cultural institutions and scholarly research. As a result, the question of how antiques are safeguarded, valued, traded, perceived, and consumed remains largely underexplored. By studying the contemporary economy of antiques, MOOVA’s prime objective is to highlight the potential of these objects regarding the safeguarding and promotion of informal heritage, sustainable consumption, new business models for ageing sectors, and local city development. More specifically, MOOVA aims to: 1) demonstrate the patrimonial role of antique dealers as vital safe-guarders of informal heritage; 2-3) explore the market structures at play within the antiques trade, its economic impact, and the supply and demand for antiques in a digital economic context; 4) understand how antiques are perceived by younger generations (Gen Z); and 5) develop a theoretical and practical model for renewing the meaning and value of these complex objects. Through selected case studies (European decorative arts) and a multi-transversal approach (cross-markets, objects, countries), the project will combine theories, data, and methods from art history, cultural economics, cognitive science, and arts marketing to investigate this topic holistically. The first stage will consist in data collection and processing, using new databases of evidence drawn from primary and secondary sources (incl. interviews and sales results), while the second will be dedicated to the development of the reevaluation model. MOOVA's overreaching goal is to progress towards more advanced scholarship in art market studies by providing tools that better fit the idiosyncrasies of markets for complex cultural goods, and to address issues related to art education, audience renewal, and job opportunities.

Keywords: cultural consumption cultural perception art markets informal heritage cultural and creative industries