Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Improvement of food safety applied biosensors by protein engineering (BIOIMPROVE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2022-04-07
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: CLOSED

Determination of the histamine content is of paramount importance for the food industry as a parameter of the hygienic quality and freshness of food, as well as to prevent scombroid fish poisoning, an allergy-like food poisoning. At present, more sensitive and user-friendly methods for histamine monitoring are needed to early detect products and raw materials susceptible of becoming hazardous for consumers. BIOIMPROVE aims to develop an improved and highly sensitive portable biosensing device for the quantification of histamine in the lower concentration range (<5 mg/l). To reach this objective, an innovative and powerful semi-rational protein engineering strategy will be used to maximize the sensitivity of the currently available histamine enzyme-based biosensor. Rather than addressing this goal by the generation and screening of large libraries, a careful selection of the most promising mutational hotspots will be performed using the structural available information in tandem with advanced computational modelling tools. Dr. Gangoiti will carry out BIOIMPROVE project at BIOLAN Microbiosensores, a Spanish SME focused on the development of biosensors capable of detecting health and food-related molecules. To support her research, she will conduct a secondment at CIC bioGUNE, a research centre that has a strong reputation in protein computational design. Thanks to this multidisciplinary research environment, Dr. Gangoiti will have the opportunity of gaining not only a high level of complementary expertise in areas of key importance in the enzyme technology field, but also the competences required for pursuing a successful research career either in industry or academy. Most importantly, the implementation of BIOIMPROVE project is expected to ensure histamine contamination to be identified at all stages of the food chain, ultimately guaranteeing food safety for European consumers.

Keywords: enzyme,protein engineering,electrochemical biosensor,food safety,histamine
Functional Redundancy of the Global Ocean Microbiome (FROM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-04-01
End date: 2024-03-31
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: SIGNED

This proposal relates to a recent debate of microbiology. Functional redundancy supposes that many taxa can realize the same functions. In this scenario, the composition of microbial communities could appear as a bad predictor of their effects on ecosystems. Functional redundancy among microbes has been suggested but also disproven, growing in a limiting debate for microbiology. Our project proposes an overview of microbial functions to answer to this debate. The innovation in our project consists in studying the ecology and redundancy of functions inferred by various methods. We will use state-of-the art microbiome datasets that spans the global ocean, enabling to study the impact of geographic scales on redundancy. The host and the candidate will bring together their complementary expertise on omics, statistics, microbes’ morphology, nutrition and interactions to compare for the first time the functionality of all microbial domains across the global ocean. Inferred functions will be analyzed against microbial taxonomy, environmental selection from abiotic variables and dispersal across the ocean to study their redundancy and ecological patterns. Novel cross-disciplinary tools will be developed that will expand the outreach of our project to research in omics (e.g. bioinformatics, computational biology), biogeochemistry, modelling, evolution or global changes. Morpho-trophic features of protistan taxa will be collected into a novel database that will represent their functional diversity. Finally, an innovative functional characterization of ecological networks will be developed to unveil the interplay between microbial interaction networks and environmental conditions. Researchers and policy-makers studying how microbes affects natural, engineered, or future ecosystems, will benefit from our project that represents a major leap forward for microbiology and functional ecology.

Keywords: functional redundancy,prokaryotes,protists,environmental microbiology,global ocean,ecosystem,functioning,trait approach,metagenomics,metatranscriptomics,interaction network
Entangled Parliamentarisms: Constitutional Practices in Russia, Ukraine, China and Mongolia, 1905–2005 (ENTPAR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Germany
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-04-01
End date: 2023-03-31
Duration (months): 60.0
Total project cost (EUR): 1220325.0
EU funding (EUR): 1220325.0
Participants: 1
Project status: CLOSED

The project addresses the entangled histories of deliberative decision making, political representation and constitutionalism on the territories of the former Russian and Qing Empires and focuses on the cases of Russia, Ukraine, China and Mongolia between 1905 and 2005. Employing the perspectives of the New Imperial History and Transcultural Studies, the project overcomes narrow state-centered approaches and takes advantage of multidisciplinary methodology crossing history and political science. The project traces parliamentary developments, the interactions among imperial and post-imperial intellectuals and their engagement in global discussions, shared imperial legacies, mutual borrowings and references, imperial and post-imperial political practices and translatability of concepts. It seeks to refute the stereotypes about inclinations towards democracy in particular national contexts by tracing relevant transnational practices and interactions and providing a nuanced political and intellectual history of parliamentarism. The team of five researchers (the PI, three PhD students and a post-doctoral researcher), will discuss and develop five individual and three cooperative studies. The PI will write a global history of parliaments and quasi-parliamentary institutions in Russia’s imperial formations (the State Duma of the Russian Empire, the congresses of soviets and the Federal Assembly of the Russian Federation). The three PhD students with relevant language skills will focus on parliamentary developments in the Ukrainian, Chinese (including Hong Kong and Taiwan) and Mongolian contexts. The post-doctoral researcher will explore the translatability of concepts between Russian, Chinese, Mongolian, Ukrainian and English. The three cooperative projects will focus on traditional institutions of deliberative decision making in the abovementioned contexts; the Communist International and institutional exchange; and the role of parliaments in major social transformations.

Keywords: new imperial history,transcultural studies
DEPLOYMENT OF DEEP ENHANCED GEOTHERMAL SYSTEMS FOR SUSTAINABLE ENERGY BUSINESS (DEEPEGS)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Innovation actions
Countries involved: Iceland,Germany,Germany,Italy,Germany,Germany,Iceland,Norway,France,France
Call: Demonstration of renewable electricity and heating/cooling technologies (H2020-LCE-2015-2, 2015)
Start date: 2015-12-01
End date: 2020-04-30
Duration (months): 53.0
Total project cost (EUR): 42173550.2
EU funding (EUR): 18982937.630000003
Participants: 13
Project status: CLOSED

Our goal with the DEEPEGS project is to demonstrate the feasibility of enhanced geothermal systems (EGS) for delivering energy from renewable resources in Europe. Testing of stimulating technologies for EGS in deep wells in different geologies, will deliver new innovative solutions and models for wider deployments of EGS reservoirs with sufficient permeability for delivering significant amounts of geothermal power across Europe. DEEPEGS will demonstrate advanced technologies in three geothermal reservoir types that provide all unique condition for demonstrating the applicability of this “tool bag” on different geological conditions. We will demonstrate EGS for widespread exploitation of high enthalpy heat (i) beneath existing hydrothermal field at Reykjanes (volcanic environment) with temperature up to 550°C and (ii) very deep hydrothermal reservoir Vendenheim with temperatures up to 220°C that is located in the Upper Rhine Graben (URG), a tertiary-age NNE directional rift enclosed in the European Cenozoic Rift System (ECRIS). ECRIS is an 1100 km long system of rifts formed in the foreland of the Alps as the lithosphere responded to the effects of the Alpine and Pyrenean orogenies (The originally planned French demonstrators of Valence and Riom are also located in rifts belonging to the ECRIS system). Our consortium is industry driven with five energy companies that are capable of implementing the project goal through cross-fertilisation and sharing of knowledge. The companies are all highly experienced in energy production, and three of them are already delivering power to national grids from geothermal resources. The focus on business cases will demonstrate significant advances in bringing EGS derived energy (TRL6-7) routinely to market exploitation, and has potential to mobilise project outcomes to full market scales following the end of DEEPEGS project. We seek to understand social concerns about EGS deployments, and will address those concerns in a proactive manner, where the environment, health and safety issues are prioritised and awareness raised for social acceptance. We will through risk analysis and hazard mitigation plans ensure that relevant understanding of the risks and how they can be minimised and will be implemented as part of the RTD approaches, and as a core part of the business case development.

Keywords: enhanced geothermal system,deep geothermal,seismic risk management,stimulation,renewable energy
Blockchain Platform to Track Chemicals along the Value Chain (ChemChain)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Netherlands
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2020-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

As there is significant market demand for enhanced flow of data and transparency throughout the lifecycle of products, to comply with existing legisltive requirements and to address emerging circular economy challenges, ChemChain supports the industry by creating a trusted and globally accepted open-source blockchain infrastructure to store, exchange, build and track chemical-related information along the supply chain. ChemChain blockchain technology is a game-changer for decentralizing infrastructure and building a trust layer in the Chemicals Supply Chain. Every time a raw material or product changes hands, from manufacture to sale, its chemicals could be documented. This creates an immutable source of information on a product’s chemical components, allowing companies to overcome current supply chain constraints. Also, it dramatically reduces time delays, added costs, and human errors that plague the chemicals supply chain today. ChemChain leads to (i) reduction of costs and simplification of procedures for demonstrating regulatory compliance, (ii) enhanced exchange of information among companies and stimulation of new synergies, (iii) increased knowledge on chemicals in products also among consumers together with a better understanding of their importance and risks, (iv) facilitated access to information on chemicals in articles also to recyclers and waste operators to manage potential environmental and health risks, and (v) generation of big data on the flow of chemicals in the society as unprecedented knowhow needed to address upcoming sustainability and circular economy challenges. Business Opportunity: Since estimated average annual total direct compliance cost with the legislation relevant to chemical companies (Europe only) approaches €9.5 billion, our project has potential for disruptive innovation and fast market up-take. The EC funding will allow us to quickly grow to €9.53 million in gross margin by 2023.

Keywords: chemicals,supply chain,communication,transparency,blockchain,decentralizing,infrastructure,trust layer,regulatory compliance,chemical big data,sustainability,circular economy,environment
Integrated Photonic Neural Networks with Arbitrary Capabilities (NeuroPhotonics)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Türkiye
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2023-09-30
Duration (months): 24.0
Total project cost (EUR): 157355.52
EU funding (EUR): 157355.52
Participants: 1
Project status: SIGNED

As data generation and transfer rates have grown rapidly over the last decades, integrated photonic systems have become the key technology enabling modern communication systems. In order to sustain future economic and societal growth, continued development of arbitrarily complex and multi-functional integrated photonic systems is therefore imperative. Traditional design of these systems relies on determining device geometries using analytical electromagnetics, after which various parameters are optimized. In contrast, the flexibility for more complicated optical functionality is currently only possible with “blank-slate” optimization routines. In these algorithms, the device structure is determined by searches through thousands of degrees of freedom, which is computationally prohibitive when targeting arbitrarily complex functionality with larger devices. To this end, this project will develop an artificial intelligence-based, universal photonic neural network architecture and its optimization framework to enable and experimentally demonstrate arbitrary photonic capabilities on-chip. For the first time, this novel approach will allow solutions for designer-specified operations including arbitrary combinations of wavelength and polarization-specific transfer functions. Resulting devices will be fabricated and characterized to demonstrate previously elusive on-chip functionality, and for rapid adoption and widespread use. Customer needs in communications and sensing applications will be specifically targeted through an industrial secondment, and a structured innovation management/commercialization plan. This framework and its industrial use represent a vast leap towards universal integrated photonic design for advancing European capability and economic drivers through innovation in future optical systems. As such, the fellowship will transform my career towards future leadership at the intersection of academic research and industrial innovation.

Keywords: silicon photonics
IMPACT OF AROMA AND AROMA INTERACTIONS ON SWEET FLAVOR PERCEPTION IN JUICES AND SOFT BEVERAGES (FLAVODRINKS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-01
End date: 2017-09-20
Duration (months): 24.0
Total project cost (EUR): 185076.0
EU funding (EUR): 185076.0
Participants: 1
Project status: CLOSED

In efforts to help consumers improve their health by reducing their consumption of sugar, salt and fat (Europea 2006/1924/EU), the European Commission recently set new standards for the formulation, production, labeling and advertising of fruit juices (Europea 2012/12/EU). Similar regulations are expected soon for soft drinks. Soft drinks have begun to suffer a poor public image because of their high content of sugar or sugar substitutes, which the beverage industry uses to counteract or mask undesirable flavors. It may be possible to avoid the need to add sugar to fruit juices and soft drinks if we can identify aroma compounds that help the consumer perceive a drink as sweet. Understanding the interaction between aromas allow act on sweetness perceived by the consumer and get drinks with less sugar added. The purpose of the work is to identify aroma compounds responsible for the sensory properties of fruit beverages and analyze how they may affect taste perception (sweet, acid and bitter). Fruit juices and soft drinks will be analyzed in order to characterize the main compounds involved in the perception of aroma as fruity, floral, green and sweet. Close attention will be paid to the chirality of identified compounds in order to study structure-aroma relationships (chemosensory approach). The ability of aroma compounds to interact in influencing taste will also be studied in order to identify synergistic or suppression effects. Moreover, perceptual interactions between aroma and taste will be studied using specific taste compounds. The innovation of the proposed study lies in applying sensory-guided multidimensional chromatographic techniques to beverages, which are complex mixtures of aroma and taste compounds. Aroma compounds will be identified using multidimensional gas chromatography coupled to mass spectrometry and olfactometry (MDGC-MS-O). Odor-odor interactions will be studied using olfactoscanning, in which a GC-O is coupled to an olfactometer.

Keywords: mdgc o,multidimensional chromatography,chirality,volatile compounds,aroma,taste,fruit juice,healthy drinks
Green Bubbles RISE for sustainable diving (GreenBubbles)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: South Africa,Italy,Italy,Malta,Türkiye,United States,Netherlands
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 1620000.0
EU funding (EUR): 1611000.0
Participants: 10
Project status: CLOSED

Recreational SCUBA divinga has become a mass leisure activity engaging millions of divers worldwide. The diving industry generates large direct and indirect revenues for coastal communities and Marine Protected Areas (MPAs). Other benefits linked to diving include the promotion of ocean stewardship, contribution to scientific research, fostering social inclusion and personal development. Yet, diving has also negative impacts, due to damage or disturbance of marine habitats and organisms and to conflicts with local communities for the access to/use of the same resources, equity issues, or cultural clashes. These aspects clearly relate to the three pillars of sustainability, covering environmental, economic and social dimensions and can only be addressed by a systemic approach. The central objective of GREEN BUBBLES is to maximise the benefits associated with diving while minimising its negative impacts, thus achieving the environmental, economic and social sustainability of the system. This will be done by: 1) Carefully assessing and modelling the system itself; 2) Developing innovative products based on the issues and needs highlighted by assessment and modelling; 3) Promoting the uptake of such products by the system designing tailored business models and marketing plans. Direct engagement with selected stakeholders (divers, professionalsb, diving operators, certification agencies - CAs, MPAs, NGOs) will ensure relevant feedback throughout the project’s lifetime, as well as effective uptake of results at the end of the project. Cutting across sectors and disciplines, and engaging participants from 3 continents, GREEN BUBBLES will put the European diving system in focus thanks to dedicated R&I with, about and for the European diving industry and will take advantage of parallel comparative work on the much more studied coral reef diving system.

Keywords: recreational scuba diving,tourism,systemic approach,marine protected areas,impacts,co management,stakeholders,ocean literacy,citizen science,quality labelling,business models,marketing
Risk Assessment and MOnitoring for BRIdges under Scour hazard (RAMOBRIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-02-07
End date: 2024-08-08
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: SIGNED

The RAMOBRIS project aims to develop a novel and multidisciplinary strategy for evaluating the risk of critical bridges against scour, combining hydrological/hydraulic and scour information deriving from both measurements and forecasting, and structural vulnerability assessments. Although scour is the leading cause of bridge failures in Europe and the rest of the world, current practices for bridge scour risk management are quite inefficient, being often based on expensive, potentially inaccurate, and time-consuming visual inspections. Moreover, current procedures do not allow an explicit quantification of the expected direct and indirect losses due to the occurrence of floods. The proposed project aims at overcoming the limitations of current procedures through a novel and multidisciplinary approach exploiting the experience of the fellow in hydraulic monitoring and analysis, with the one of the host and partner organisations in structural health monitoring, structural analysis, risk assessment, flood forecasting and scour analysis. The objectives of RAMOBRIS will be [1] to critically review monitoring techniques available for assessing bridge scour risk; [2] to define a cost-effective monitoring strategy for forecasting and measuring river flow, bridge scour, and bridge-performance; [3] to define an innovative probabilistic framework for real-time scour risk monitoring, using a Bayesian approach to combine the information from heterogeneous monitoring and forecasting systems; [4] to provide a framework for bridge vulnerability assessment based on nonlinear structural analysis under different hydraulic loads and for different bridge typologies, and to estimate current and future risk of bridge collapse due to scour, taking into account climate change effects. The research achievements will significantly contribute to the objectives of the European Programme for Critical Infrastructure Protection and to achievement of a resource efficient economy and society.

Keywords: bridge scour,structural health monitoring,risk assessment,vulnerability analysis,flood forecasting