Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
sCalable solutions Optimisation and decision tool Creation for low impact SAF Production chain from a lIpid-rich microalgae sTrain (COCPIT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: France,Spain,Denmark,Germany,Greece,Italy
Call: Development of algal and renewable fuels of non-biological origin (HORIZON-CL5-2022-D3-03, 2022)
Start date: 2023-10-01
End date: 2027-09-30
Duration (months): 48.0
Total project cost (EUR): 5467603.31
EU funding (EUR): 4999497.23
Participants: 12
Project status: SIGNED

COCPIT´s ambition is to enhance the SAF production chain by bringing ground-breaking innovations at each thread of it. It aims also to provide investors with a human centred decision tool in a "test before invest" spirit with a high confidence level to de-risk investments. A lipid rich microalgae strain is cultivated in an intensified reactor coupled to semi-transparent photovoltaic panels transforming harmful light spectrum into electrical power. The transformation of algal biomass into SAF is studied using two alternative pathways: The most mature one, HEFA, and a very promising one HTL. The project focuses on the circularity, productivity, sustainability and economic viability of the chain. For HEFA pathway, efficient, low impact and regenerable ionic liquids are used to extract lipids and to catalyse hydrotreatment. For HTL pathway, a continuous reactor, tailored to SAF production from the chosen strain is designed and constructed to reduce clogging issues and to size with higher precision the heat exchangers. Furthermore, the mechanistic models that are developed and used in the design increase the scalability of the HTL. Biocrude upgrading is led to give a high flexibility between SAF and shipping fuel production. The system is designed in a circular way to reduce by-products, feed system with endogenous hydrogen, recirculate nutrients and reduce its water intensiveness. The whole integrated system is simulated with Unism software and all technical, economical, environmental and life cycle indicators are calculated under the COCPIT decision tool and typical scenarios are compiled. The decision tool is delivered within a marketplace that puts at investor’s service a range of required technological solutions, equipment and skills. It helps them also to choose the best technology that fits their project specificities. The ambition of this tool is to continue growing up after the end of the project to include all certified and promising SAF production pathways.

Keywords: sustainable aviation fuels,hydrothermal liquefaction,microalgae,decision tool,lca,techno economic assessment,hefa,system integration,chemical engineering
Resolving magnetic ORIGINs of the hot solar atmosphere (ORIGIN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-06-01
End date: 2027-05-31
Duration (months): 60.0
Total project cost (EUR): 1488649.0
EU funding (EUR): 1488649.0
Participants: 1
Project status: SIGNED

The outer atmosphere of the Sun, the corona, is a unique plasma laboratory. It provides key insights into fundamental universal processes such as magnetic reconnection and particle acceleration. Yet, the very existence of the corona in itself is not well understood. It is composed of million Kelvin hot plasma trapped by magnetic fields, and overlies the much cooler 6000 K photosphere, the visible surface of the Sun. All sun-like stars possess such magnetically dominated hotter coronae overlying cooler photospheres. How do magnetic fields regulate mass and energy transport from the cool photosphere to sustain the overlying hot corona? This is a long-standing problem in astrophysics, which lacks a comprehensive explanation, despite proposals of different coronal heating models over the past five decades. The progress is hampered due to the lack of a solid, observationally validated framework of how the corona is magnetically coupled to the photosphere. We propose a holistic strategy to tackle this challenging problem of developing a framework for coronal heating by probing the elusive photosphere-corona connection and comprehensively testing the importance of different magnetic processes in the heating of the outer solar atmosphere. Through this strategy, we will identify key magnetic processes in the cool photosphere that regulate the hot atmosphere. Project ORIGIN will achieve this timely goal by exploiting unique, multi-wavelength observations from the recently launched Solar Orbiter mission, in combination with realistic radiation magnetohydrodynamic (MHD) simulations, and thus gain ground-breaking new insights into the magnetic origins of the hot solar atmosphere.

Keywords: solar observations,magnetohydrodynamics,simulations,solar orbiter,heliophysics
Phycosphere Epibionts-mEdiated Resistance againSt fungi (PEERS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy,Finland
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-03-16
End date: 2028-03-15
Duration (months): 24.0
Total project cost (EUR): 209483.28
EU funding (EUR): 209483.28
Participants: 2
Project status: SIGNED

Symbionts are essential components of healthy organisms, assuming functions often mediated by chemical communication. In aquatic environments, microbial primary producers such as phytoplankton possess complex epibiotic bacterial communities that contribute to their physiology by secretion of bioactive molecules. However, the role of symbiotic bacteria in mediating the host’s interaction with other coexisting microbes is poorly studied. PEERS’ aim is to unravel the key symbionts of phytoplankton mediating host interaction with zoosporic fungal parasites through the biosynthesis of antifungal compounds. Using a tripartite interaction model involving phytoplankton host, bacterial symbionts and fungal parasites, we will study (i) the diversity of bacteria associated with healthy and diseased host populations, and (ii) the symbionts’ biosynthesis of antifungal compounds. This study integrates molecular ecology, metabolomics, and bioactivity screenings coupled with advanced statistics and data processing methods. Aquatic microbial communities will be collected from the Baltic Sea during the secondment, where the phytoplankton-host and parasite interactions during fungal disease outbreaks are well documented. PEERS will address a fundamental ecological question about the role of symbiotic bacteria in driving host-fungal parasite interaction in the aquatic environment, providing critical knowledge for understanding future variations in aquatic biomes under current environmental changes. Additionally, it provides a perfect model system to discover antifungal chemical signals with industrial applications. PEERS offers cutting-edge training opportunities to generate results at the forefront of innovation in aquatic ecology and biotechnology. Moreover, it offers transdisciplinary networking possibilities supporting a One Health research approach, with significant impact on my career progression.

Keywords: phytoplankton,zoosporic fungi,chytrids,antifungal resistance
Together for RISc-V Technology and ApplicatioNs (TRISTAN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: Germany,Austria,Italy,France,Poland,Netherlands,Belgium,Türkiye,Finland,Romania,Switzerland
Call: HORIZON-KDT-JU-1-IA-Focus-Topic-1-Development of open sources RISC-V building blocks (HORIZON-KDT-JU-2021-1-IA, 2021)
Start date: 2022-12-01
End date: 2026-06-30
Duration (months): 43.0
Total project cost (EUR): 52524826.72
EU funding (EUR): 15238535.03
Participants: 50
Project status: SIGNED

TRISTAN’S overarching aim is to expand, mature and industrialize the European RISC-V ecosystem so that it is able to compete with existing commercial alternatives. This will be achieved by leveraging the Open-Source community to gain in productivity and quality. This goal will be achieved by defining a European strategy for RISC-V based designs including the creation of a repository of industrial quality building blocks to be used for SoC designs in different application domains (e.g. automotive, industrial, etc.). The TRISTAN approach is holistic, covering both electronic design automation tools (EDA) and the full software stack. The broad consortium will expose a large number of engineers to RISC-V technology, which will further encourage adoption. This ecosystem will ensure a European sovereign alternative to existing industrial players. The 3-year project fits in the strategy of the European Commission to support the digital transformation of all economic and societal sectors, and speed up the transition towards a green, climate neutral and digital Europe. This transformation includes the development of new semiconductor components, such as processors, as these are considered of key importance in retaining technological and digital sovereignty and build on significant prior investments in knowledge generation in this domain. Development strategies leveraging public research funding that exploit Open-Source have been shown to boost productivity, increase security, increase transparency, allow better interoperability, reduce cost to companies and consumers, and avoid vendor lock-ins. The TRISTAN consortium is composed of 46 partners from industry (both large industries as well as SMEs), research organizations, universities and RISC-V related industry associations, originating from Austria, Belgium, Finland, France, Germany, Israel, Italy, the Netherlands, Poland, Romania, Turkey and Switzerland.

Keywords: risc v,opensource,open source,embedded processors,ai ml driven applications,mobile communication,automotive power control,processor peripherals
CLIMATE-edGE: Climate Leadership, Innovation, Machine Learning, and Analytics for Transformational Evaluation of the Green Economy (CLIMATE-edGE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-07-01
End date: 2031-06-30
Duration (months): 60.0
Total project cost (EUR): 1434800.0
EU funding (EUR): 1434800.0
Participants: 1
Project status: SIGNED

Proposal Summary: The private sector plays a crucial yet complex role in the climate transition. While responsible for a significant portion of global greenhouse gas emissions, it also holds vast investment capital and innovative potential. CLIMATE-edGE will address a critical question: Under what conditions do private sector climate commitments translate into measurable actions, and what factors determine whether firms and sectors are effectively aligning their climate promises with actual performance? By examining publicly traded firms in the EU/EEA, the UK, and the US, the research will uncover complex relationships between climate commitments (climate talk) and climate performance (climate walk), in turn reflecting on the impact of regulatoryThe private sector plays a crucial yet complex role in the climate transition. While responsible for a significant portion of global greenhouse gas emissions, it also holds vast investment capital and innovative potential. CLIMATE-edGE will address a critical question: Under what conditions do private sector climate commitments translate into measurable actions, and what factors determine whether firms and sectors are effectively aligning their climate promises with actual performance? By examining publicly traded firms in the EU/EEA, the UK, and the US, the research will uncover complex relationships between climate commitments (climate talk) and climate performance (climate walk), in turn reflecting on the impact of regulatory measures aimed at advancing climate efforts in the green economy. This project will break from traditional approaches by developing a novel database which will contain the full universe of climate commitment and performance data; it will then apply data transformation techniques to enhance interoperability of these data and, finally, it will conduct both advanced econometric and machine-learning analyses to uncover hitherto hidden and latent patterns in the private sector’s climate talk-walk efforts.

Keywords: machine learning,private sector climate transition,climate commitment,climate performance,climate innovation,climate finance
BavAR[t], an augmented reality game for democratizing art and culture. (BavARt)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: France
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-06-01
End date: 2024-05-31
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Cultural institutions and museums are currently really eager to target a broader audience and to have visitors coming back at a regular rate to reignite the cultural sector in the post-covid era. Digital technology provides an amazing opportunity for cultural institutions by allowing them to be ubiquitous, to engage with new audiences, to help people to prepare and share their visit and to forge new relationships with their visitors. BavAR[t] is totally designed to cope with such difficulties, by offering both a game AND a platform for professionals, in augmented reality, dedicated to art and culture. BavAR[t] is a game, similar to PokémonGo, except that instead of capturing the famous small and cute Japanese monsters, players catches... artworks! And for artwork capturated, players collect points, which can then be exchanged for cultural vouchers, such as cinema or theater tickets. But BavAR[t] is so much more than a game. The game is only a pretext to enable cultural mediation and communication with a wider public, not necessarily always inclined to enter in cultural institutions. BavAR[t] is also a B2B platform, allowing art and culture professionals, such as museums, galleries or theater, to quickly and easily create an augmented reality experience for their visitors or their target. This platform format allows all actors from this sector to develop their innovation potential, offering them a new revenue source, and allows them to focus on the content itself, and the communication strategy rather than on the technical difficulties and costs inherent to the development. In this proposal, AR[t] Studio propose to - Deploy BavAR[t] at a European scale, to encourage artwork circulation, promote art & culture by spreading art everywhere on map - Develop guided tours, allowing cultural institutions to offer full personalized guided tours to their visitors or their targets. A democratization of art by the gamification and the use of deep tech!

Keywords: augmented reality,art,culture,game,gamification,democratizing art and culture
Aromatic Foldamer Mimics of B-DNA: Targeting the Alpha-Helix (FOLOF)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Protein-nucleic acid interactions (PNIs) play a central role in biology and their control would enable long-desired biological interventions and future therapeutic applications. However, synthetic molecules that reproduce the overall shape and surface features of nucleic acids to interfere with PNIs have been lacking because, up to now, it has not been possible to design such extended and complex abiotic interactions interfaces. Due to their distinct chemical composition, predictable shapes, large size and conformational stability, aromatic oligoamide foldamers (AOFs) are prime candidates for breaking new ground in this field. FOLOF aims to develop AOF-based surface mimics of the B-DNA double helix targeted to the large ensemble of sequence-selective PNIs mediated by alpha-helices. Based on the PI’s expertise in AOF science, FOLOF will proceed by 1) expanding the chemistry tool box to enable specific design objectives; 2) optimizing the automation of AOF synthesis for the fast delivery of long sequences; 3) identifying structural features of protein-foldamer complexes and specific foldamer features that make them outcompete DNA binding; 4) establishing protocols to iteratively improve protein binding affinity and selectivity for AOFs, and AOF-DNA covalent hybrids; and 5) developing computational tools for ab initio AOF-based DNA mimic design. Through a strategic combination of chemical synthesis, computational predictions, crystallographic structural analysis, binding studies, and screening tools, FOLOF will push the production of abiotic molecular mimics of nucleic acids to a completely new ensemble.

Keywords: foldamers,molecular recognition,alpha helices,protein surface recognition,molecular design
Strengthening the research capacity of Turkey in innovative business models for the hospitality sector (REMODEL)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Türkiye,Spain,Ireland
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 1499827.5
EU funding (EUR): 1499827.5
Participants: 3
Project status: SIGNED

REMODEL aims to strengthen BUU R&I capacity and skills through leveraging the experience and state-of-the-art knowledge and digital tools made available by twinning partners ULE and ATU in business model innovation (BMI). BUU staff will significantly enhance their management and administration skills, thanks to the capacitation and networking activities. A novel BMI laboratory (BMI Lab) will be created leveraging and combining the strengths of ULE consumer behaviour analysis laboratory and ATU DiceLabs, and will become instrumental for the execution of the R&I part of the project by applying the acquired knowledge and skills in consumer behavioural analysis, neuromarketing, research management, business innovation, leadership and entrepreneurship, developing business models for 10 Turkish SMEs in the hospitality sector in the context of COVID-19 pandemic. The BMI Lab will be an R&I pole for BUU academic staff and will bring benefits to SME in all sectors, contributing to business sustainability and employment creation. A long-term scientific strategy will be developed including staff exchanges, the definition of common joint R&I programmes related to BMI and the creation of an international master on business management in the hospitality sector. REMODEL goals are perfectly aligned to the expected topic outcomes and impacts, as will increase staff capacitation and scientific excellence and will provide a state-of-the-art BMI Lab to transform BUU in a leading institution in Turkey on BMI in the hospitality sector, boosting HE-Industry cooperation, the preparation and leadership of EU funded proposals, increasing its reputation within a defined network collaborators under a long-term cooperation strategy, and advocating novel R&I incentives schemes to Turkish funding agencies and policy makers. This strategy will sustain R&I, facilitate the exchange of students, researchers and academic staff, and increase the mobilization of resources at national and EU-levels.

Keywords: innovative business models,hospitality sector,tourism,entrepreneurship,neuromarketing,data mining,data analysis,consumer behaviour,covid 19 impact
Structural exploration of GD3 ganglioside-COVID spike Protein Interaction and siglec-7 Role in inhibition of virAL infection (SPIRAL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-05-01
End date: 2026-04-30
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: SIGNED

The present project focuses on deeply comprehending the molecular basis of glycan recognition events by key protein receptors at atomic level, directly connected to processes related to immune response, infection and cancer. We will elucidate using Nuclear Magnetic Resonance (NMR) and other biophysical techniques the binding preferences of the recognition event between GD3 ganglioside and the Spike proteins of OC43 and HKU1 human coronavirus (HCoV) variants, along with Siglec-7. The role of Siglec-7 in inhibiting the HCoV viral infection will also be addressed. This research will make a significant and direct contribution by unveiling the roles of glycosylation patterns and cell receptors in HCoV infection mechanisms. Dr. Bermejo, the applicant, defended her PhD Thesis almost five years ago and was awarded a MSCA-IF fellowship for the past three years. During this time she has grown into an excellent researcher in chemical biology, possessing practical experience in organic and peptide synthesis, drug design, lipid nanoparticles formulation, cell culture and binding assays. Through the awarding of this fellowship she will join the lab of Prof. Jesus Jiménez-Barbero the Scientific Director of the host institution (CIC bioGUNE) and Leader of the Chemical Glycobiology lab. He is one of the best-known scientists in glycan research at the national and international levels. Thanks to this action, Dr. Bermejo will consolidate her multidisciplinary scientific proficiency, acquiring new competences in enzymatic synthesis and protein expression and purification and trend setting NMR concepts and techniques. She will contribute to the host with her expertise in glycan and glycoconjugates synthesis, and will bring her expertise in liposomal formulation, setting up a microfluidics device within the group.

Keywords: carbohydrates,nmr,siglecs,viral spike protein