Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Transport and signalling in Polarized Cells (TRANSPOL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,France,Switzerland,United Kingdom,Israel,Denmark,Poland,Germany,United Kingdom,United Kingdom,Germany
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2010-12-01
End date: 2014-11-30
Duration (months): 48.0
Total project cost (EUR): 3835980.0
EU funding (EUR): 3835980.0
Participants: 11
Project status: CLOSED

Aberrant molecular signalling and intracellular trafficking are the molecular cause of many human diseases. TRANSPOL is an interdisciplinary initial stage training network (ITN) at the intersection of cell/molecular biology and membrane physics aimed specifically at the molecular understanding of the functional relationship between intracellular trafficking and cellular signalling and their relevance to human diseases. The importance of intracellular trafficking processes serving as an integral part of signalling has only recently received broader attention and demands further in-depth analysis. This ITN is specifically designed to bridge this gap between “conventional” signalling cascades and processes of membrane fusion, fission and intracellular trafficking. To tackle this important task we have assembled a unique multidisciplinary consortium combining top European scientists from the fields of cell biology, biochemistry, and physics as well as specialists from the private sector. The scientific objectives will concentrate on a better understanding of ligand/receptor-mediated signalling mechanism across the membrane, the lipid/protein interface in endocytosis, the signalling properties of endosomes, and deregulated trafficking and signalling pathways in disease. Three private enterprises are fully integrated in this ITN underlining its intersectorial character. The multidisciplinary research and training program comprises cell biology, protein and lipid biochemistry, biophysics, computational simulations, protein design and systems biology. TRANSPOL has designed a structured 3-year curriculum providing the following hallmarks: 1. A joined academic and industrial training program/2. A combination of local and network wide European training/3. A training in scientific and complementary skills including soft skills/4. An in-depth scientific training focused on a specific PhD topic/5. Doctoral examination under the auspices of external international examiners.

Keywords: vesicular trafficking,signalling,cell biology,biophysics,membrane dynamics,membrane mechanics,endocytosis,cell polarization
Ecological Function and Biodiversity Indicators in European Soils (ECOFINDERS)

Framework: FP7 — Cooperation
Programme: Environment (including Climate Change)
Destination: Sustainable management of resources
Action type: Collaborative project
Countries involved: France,United Kingdom,Denmark,Germany,Germany,European organisations area,Sweden,Netherlands,Netherlands,Sweden,Ireland,Portugal,Italy,Ireland,United Kingdom,United Kingdom,United Kingdom,Netherlands,Slovakia,China,Slovenia,Italy,Spain,United Kingdom,Slovakia
Call:  (FP7-ENV-2010, 2010)
Start date: 2011-01-01
End date: 2014-12-31
Duration (months): 48.0
Total project cost (EUR): 9985223.51
EU funding (EUR): 6999930.0
Participants: 28
Project status: CLOSED

The strategic goal of EcoFINDERS is to provide the EC with tools to design and implement soil strategies aimed at ensuring sustainable use of soils, including: i) Characterisation of European soil biodiversity; ii) Determination of relations between soil biodiversity, soil functions and ecosystem services; iii) Design of policy-relevant and cost-effective indicators for monitoring soil biodiversity. The project will: i) Develop and standardise tools and procedures to measure microbial and faunal diversity; ii) Describe the diversity of soil organisms (microbes and fauna), iii) Decipher the interactions among soil organisms and with plants through foodwebs and iv) Determine the role played by soil organisms in soils ecosystem services (nutrient cycling, carbon storage, water retention, soil structure regulation, resistance to pests and diseases, and regulation of above-ground diversity); iii) Establish cost-effective bioindicators for measuring sustainability of the microbial and faunal diversity and their associated functions (using a combination of metrics and meta-analysis); iv) Evaluate the economic value of ecosystem services, the added value of these bioindicators; v) Develop and implement effective communication strategies to engage the European public around issues associated with the sustainability of soil biodiversity. The overall concept of the project is to develop and integrate the following activities: i) Decipher the links between soil biodiversity, activities, functioning and ecosystem services; ii) Combine three types of approach: observation, experimentation, and computation; iii) Assess the impact of environmental conditions; iv) Integrate information on microbes, fauna and plant communities and analyse how these compartments interact. The general hypotheses are: changes in soil biodiversity indicate the direction and rate of changes in soil functions and associated ecosystem services; application of cost-effective bioindicators brings an economic added value to sustainable soil management.

Keywords: biodiversity,processes,functions,services,bioindicators,economy,micro- & macro-organisms,long-term observatories,highthroughput analysis,modeling,atlantic,boreal,continental,mediterranean
Science based precision processing for future healthy, structured and tasteful fruit and vegetable based foods: an integrated research and training program. (HST-FOOD-TRAIN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium,United Kingdom,Germany,Netherlands,Belgium
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-01-01
End date: 2014-12-31
Duration (months): 48.0
Total project cost (EUR): 2632038.19
EU funding (EUR): 2632038.19
Participants: 5
Project status: CLOSED

A science based approach is required to fully unlock the potential of fruit and vegetable (FV) matrices in future innovative FV-based commodities that retain bio-available, health-promoting components within the boundaries of consumer preference, acceptance and needs and environmental and legal issues. HST FOOD TRAIN objectives are: to structure initial research training to equip fellows with all skills to act as future multi-disciplinary experts in academia and the private sector; to understand and quantify the relation between structure and rheology/texture, flavor and nutrient bio-accessibility of FV-based foods; to use these relations in exploiting the endogenous potential of raw materials; and to develop a method for evaluation of substantial equivalence of new technologies in terms of product composition. HST FOOD TRAIN will reach the objectives through (i) A consortium of two universities (KULeuven P1 and UoR P2), a private research institute (DIL P3), two large companies (Coca-Cola P4 and Unilever P5) and an SME (NC Hyperbaric P6). (ii) The implementation of a research program on novel and existing structure-enabling and preservation processes with four workpackages: WP1: Processing, microstructure and physical functionalities (P5,P4,P1); WP2: Processing, food structure, composition and bio-accessibility (P1,P5,P4); WP3: Processing, food structure, composition and flavor (P2,P4,P5); WP4: Substantial equivalence of novel processing techniques (P3,P6,P1,P2). (iii) An integrated training program on specialized scientific/technological courses, a comprehensive set of complementary skills and exposing fellows to the academic and private sector via secondments and visits (iv) An organizational structure securing optimal interaction between general assembly, supervisory board, researcher council, workpackage groups and site supervisors and mentors to the benefit of the fellows. The program will recruit 7 ESRs on long term projects and 6 ESRs + 3ER on short term projects.

Keywords: food products,food technology,food structure,health components,flavor attributes,microscopy,lc and gc analysis,sensory analysis,processing technologies,shelf life,physical stability
TreatPolyQ – Industrial Academic Initial Training Network towards treatment of Polyglutamine Diseases. (TREATPOLYQ)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Germany,France,Sweden,Israel,United Kingdom,Switzerland,Portugal,United Kingdom,Denmark,Sweden,Denmark,Italy
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-03-01
End date: 2015-02-28
Duration (months): 48.0
Total project cost (EUR): 3757318.0
EU funding (EUR): 3757318.0
Participants: 16
Project status: CLOSED

Protein aggregation is a hallmark of many late onset neurodegenerative disorders including Parkinson’s Disease (PD), Alzheimer’s Disease (AD), amyotrophic lateral sclerosis (ALS), prion diseases as well as the group of polyglutamine diseases (polyQ). The aim of this proposal is to create a network of European partners bridging important basic mechanisms involved in proteinopathies, research of model diseases and treatment approaches. The “TreatPolyQ” network will focus on two main representatives of the polyQ diseases: Huntington’s disease as the most common polyQ disease as well as spinocerebellar ataxia type 3 (SCA3) as the most frequent autosomal-dominantly inherited ataxia. Patients suffer from a multitude of neurological symptoms including movement abnormalities with late onset and in a progressive manner. Up to now, no treatment or cure is available. The network will be consisting of a rare combination of experts from basic and translational research, including a Nobel prize laureate, four industrial partners (two medium, and two small companies, all incorporated as full participants) and academic leaders of the field. The network not only focuses on one special aspect of a disease but spans several important disease-associated mechanism as well as promising treatment strategies for HD and SCA3 (protein transport, protein folding, protein degradation via both the ubiquitin-proteasome system and autophagy), likely to be important across a range of neurodegenerative diseases. In order to implement these research projects, extensive collaborations and temporarily personnel secondments of the involved researchers will take place, enhancing interdisciplinary transfer of knowledge. Beyond the personalized local training plan for each employed researcher within the Network, there will be 4 structured courses covering aspects ranging from structural biology to protein degradation to model organisms and drug development, including soft skill training.

Keywords: health sciences,rare diseases,neurobiology,neurology,neurochemistry
Innovative Methods of Separated Flow Control in Aeronautics (IMESCON)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Poland,United Kingdom,Belgium,France,Poland
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-05-01
End date: 2015-04-30
Duration (months): 48.0
Total project cost (EUR): 2246263.0
EU funding (EUR): 2246263.0
Participants: 6
Project status: CLOSED

The IMESCON network is a high quality training network to produce well qualified researchers in the area of active flow control and new helicopter technology. This training programme of best quality early stage and experienced researchers from industry and academia will combine expertise from fluid dynamics, composite material, Micro Electro Mechanical Systems (MEMS), experimental techniques and numerical modeling of coupled multiple simultaneous physical phenomena. Proposed research project of mutual interest to partners will address key questions in the complex multi physics phenomena research related to active flow control with the application of the novel piezoelectric materials. In energy consuming applications like aircraft operation active flow control is effective method of substantial fuel consumption and thus CO2 emission reduction. Flow control methods influence the flow unsteadiness, thus impact the increased durability of the manufactured elements and noise reduction. Combination of the two cutting-edge technologies, the MEMS and the active flow control will provide an excellent training and career development path for researchers who wish to work on analysis of the combined effects of multiple physical phenomena in environment-friendly modern technologies. Proposed project will foster existing long term collaboration between partners and create new collaborations through recruited researchers. The project outcomes will both serve the designers of the next-generation aircrafts and at the same time strengthen the human potential in R&D in Europe. IMESCON is Marie Curie ITN training programme involving 2 large European helicopter designers and manufacturers, 2 SMEs specialised in MEMS, 3 world class academic research groups and prime engineering innovation partner. The strong involvement of the industry will shape the training needs of the researchers and increase their employability.

Keywords: environmental impact,exhaust emissions,aircraft design,helicopters,simulation engineering,aerodynamics,materials engineering,computer engineering,active control,optimization
MANUFACTURING AND APPLICATIONS OF NANOSTRUCTURED MATERIALS (MANANO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Netherlands,France,Portugal,Spain
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-04-01
End date: 2015-03-31
Duration (months): 48.0
Total project cost (EUR): 2313945.8
EU funding (EUR): 2313945.8
Participants: 7
Project status: CLOSED

Nanotechnologies and nanostructured materials is expected to be the most promising area of technological development and among the most likely to deliver substantial economic and societal benefits to the EU in the 21st century. It is a time of rapid advance in the development of these technologies, which can organize materials at the nanoscale and tailor their properties. This offers exciting possibilities in virtually all sectors of EU activity and could create entirely new industries. However, the exploitation of nanomaterials by European industry has been disappointing and one of the critical reasons for this is a general shortage of scientists/engineers with the knowledge to undertake relevant research and transfer the research findings into industrial production. The aim of the proposal is to encourage the very best researchers to get jobs in EU industry, where they can create these breakthrough opportunities. This will be achieved by giving them intellectually stimulating and industrially relevant research projects that will be undertaken in collaboration with universities and industry, and include industrial secondments together with comprehensive technical and complementary skills training. A network of 5 universities and research institutes, and 10 companies from 8 EU countries will be set up to carry out the integrated research and training programme. The research will include new nanomaterials for organic electronics, lithium ion batteries, solar cells on roof tiles and on flexible polymers, ultra-light aerogels for transportation and an innovative technique for 3D characterization at the nanoscale. The network will train a new generation of ESRs in the disciplines needed to understand nanotechnology and the complementary skills to enhance their career progression. All recruits employed in the programme will be ESRs and the partners will provide experienced researchers from their own staff without charge to the European Commission

Keywords: technological sciences,physical sciences,nanostructure,nanomaterials,processes for nanomaterials
Yeast biodiversity as a source of innovations in food and health (CORNUCOPIA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Sweden,Denmark,Belgium,Italy,Czechia,Netherlands,Spain,Denmark,Netherlands
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2011-02-01
End date: 2015-04-30
Duration (months): 51.0
Total project cost (EUR): 3426775.0
EU funding (EUR): 3426775.0
Participants: 10
Project status: CLOSED

Cornucopia will train a new generation of young scientists focusing on less studied yeasts with interesting traits, which could be applied in the food and health sectors. Yeasts are a divergent group of fungi that predominantly exist as unicellular organisms. The baker's yeast Saccharomyces cerevisiae is by far the best known because of its role in producing beverages, baking and recombinant drugs, such as insulin. S. cerevisiae is also the main model for the analysis of common features of all eukaryotic cells, and has been used in pioneering the development of several molecular biology, genomics and post-genomic tools. However, the yeast kingdom includes more than 1.500 other species that display a variety of unusual characteristics, and play an important role in their natural environments, but have so far been only poorly studied. These yeasts represent a large untapped potential to develop novel food and health related processes and products. We will make use of thousands strains available within Cornucopia to screen, using a variety of microbiological, analytical chemistry and bioinformatics techniques, for traits of interest to industry. such as ethanol-, acid- and osmo-tolerance, aromatic and off-flavor compounds and probiotic properties. Our young researchers will develop novel species-specific molecular, genetic and post-genomic tools to find out which genes determine the superior traits. They will “domesticate” new isolates so that they can be easily handled in the lab, and develop scale-up cultivations for applied purposes. We will benefit from yeast biodiversity and open new avenues within fundamental and applied research. Cornucopia, consists of seven leading yeast academic laboratories and three leading European industry partners, will provide a unique environment to develop strong academia and industry oriented careers, in-depth training in major experimental technologies used in yeast research and the industrial application of innovative ideas.

Keywords: yeast,biodiversity,non-conventional yeasts,novel food products,probiotics,alcoholic beverages,aroma profile,stress tolerance
Chemical Bioanalysis (CHEBANA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Sweden,Lithuania,Spain,France,Finland,Ireland,Switzerland,United Kingdom,Austria,Italy,Germany,United Kingdom
Call:  (FP7-PEOPLE-2010-ITN, 2010)
Start date: 2010-12-01
End date: 2014-11-30
Duration (months): 48.0
Total project cost (EUR): 5757837.0
EU funding (EUR): 5757837.0
Participants: 13
Project status: CLOSED

Chemical Bioanalysis aims for retrieving selective information out of complex biological systems. Sensors, probes and devices are the future tools of medicinal diagnostics, environmental monitoring, food analysis and molecular biology. The ITN CHEBANA provides interdisciplinary research training for early stage and experienced researchers and focuses on the most important techniques in the field. These are based on fluorescence, electrochemistry and mass spectrometry. Eleven excellently qualified academic partners (with well documented expertise) along with one of Europe’s leading industrial companies in the diagnostic area will provide a network of research activities, short courses and classes that are complemented by skill training and career development events. In fact, we believe that we have unified Europe's leading experts in these fields, many of which outperform their American and other colleagues. Moreover, joint research projects between the partners build the foundation of the training network. The research activities are divided into four overlapping areas: * sensor development for the detection of small analytes, * monitoring of biomolecular interactions, * analysis of cellular function, and * development of diagnostic tools. Interdisciplinary expertise and specialized techniques are mandatory in order to accomplish these challenges, and this cannot be provided at a single institution at the required level. Therefore, a European hub for research and training in the fast developing field of Chemical Bioanalysis is assembled by co-supervised PhD theses, postdoctoral training, workshops and summer schools bringing together the individual expertise of the partners from academia and industry. Eventually, this ITN will provide highly specialized experts that are urgently looked for by the respective European industry.

Keywords: analytical chemistry,spectrochemistry,bioanalysis