Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Production of Sustainable Self-Compacting Concrete (PROSEC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2013-02-04
End date: 2015-02-03
Duration (months): 24.0
Total project cost (EUR): 278807.4
EU funding (EUR): 278807.4
Participants: 1
Project status: CLOSED

Concrete is the most widely consumed material in the world, after water. However, conventional concrete technology requires slow, heavy, noisy, expensive, energy-consuming and often dangerous mechanical vibration to compact the concrete and to develop strength and durability. Modern technology; Self-Compacting Concrete (SCC) is now available, where concrete can simply flow freely into the pre-formed moulds, or formwork, and eliminates the need for compaction. Despite of the steady increase in SCC usage in Europe and worldwide, its adoption in general construction has not been as rapid as expected. The full benefits of SCC are far from being exploited. One of the main reasons for this is its high materials costs (one and half times) compared to conventional concrete. This is because SCC requires a substantial quantity of fine powder to give the concrete the necessary cohesion to achieve its flowing properties, and prevent segregation. Special high range water reducers are essential for providing the high filling ability required. Sometimes, viscosity modifying admixtures are also required to prevent segregation and bleeding in the fresh mix. The main objective of this project is to increase the economical (i.e. reduce materials costs) and environmental (i.e. use wastes) benefits by examining the potential of using quarry waste fines and novel cost effective and environmentally friendly admixtures for SCC mixes. The proposed Incoming International Fellow has extensive research experience in various chemical admixtures for cement and concrete. He will bring knowledge to Europe in developing/modifying novel admixtures for use in the proposed application. The outcomes of the research will lead to the production of an efficient sustainable construction material that will have a positive impact on the costing, environment and society.

Keywords: technological sciences,materials technology,concrete engineering,concrete technology
Multifunctional Magnets Through Rational Design (FUNCTIONAL MAGNETS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-11-19
End date: 2014-11-18
Duration (months): 24.0
Total project cost (EUR): 209033.4
EU funding (EUR): 209033.4
Participants: 1
Project status: CLOSED

The aim of this project is to rationally design innovative multifunctional magnetic framework materials using new metalloligand and organic radical groups. This will lead to tailored magnetic properties with potential application in a range of fields, such as data storage, computing and spintronics. The metalloligand and radical groups are specially designed to impart specific magnetic interactions and function to the frameworks. This has the two-fold advantage of not only using the material for sensing external stimuli, but post-synthetically modifying the magnetic properties of the materials. The highly innovative goal is the realisation of multifunctional materials for applications in fields where tailored and tuneable magnetism is advantageous

Keywords: inorganic chemistry,molecular magnetism,metal-organic frameworks,rational design
TARGETED DELIVERY OF NEW ANTISENSE MOLECULES FOR REGENERATION ENHANCEMENT AFTER SPINAL CORD INJURY (SCIREGENASENSE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Portugal
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2013-01-01
End date: 2014-12-31
Duration (months): 24.0
Total project cost (EUR): 157748.4
EU funding (EUR): 157748.4
Participants: 1
Project status: CLOSED

Spinal cord injury (SCI) leads to severe physical and psychological damages. Classical pharmacotherapeutics have had limited success to treat this clinical condition and full recovery remains unachievable. With the understanding of the molecular pathology involved in neuronal injury and regeneration, new molecular targets are now under investigation. Our aim is to develop an antisense gene therapy approach mediated by single-stranded antisense oligonucleotides (ssAONs), targeted against inhibitors of axonal regeneration, in conjugation with a specific delivery platform for affected neuronal cells. The innovation of our strategy is two-fold: (1) it relies on the use and new developments of modified antisense oligonucleotides (LNA based 3rd generation ssAONs) with virtually no associated toxicity and an improved capacity to simultaneously down-regulate several genes involved in the inhibition of axonal regeneration after SCI; (2) the potential of the biodegradable and non-toxic biomaterial chitosan will be evaluated for the development of a multifunctional system capable of addressing the problem of low cellular uptake of naked oligonucleotides and especially the specific targeting of neuronal cells. The proposed ssAON strategy has immense benefits and its exploitation in the nervous system can have major implications for the treatment of several diseases in general. In conjugation with a specific delivery platform for neural cells this technology can be a major advancement in the improvement of neural regeneration after spinal cord injury.

Keywords: health sciences,neurosciences,dna therapy,antisense technology,nanobiotechnology,drug delivery,biomaterials
Dynamic axial chirality of tertiary aromatic amides, applications in asymmetric synthesis. (DYNAMAX)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2013-10-01
End date: 2016-01-20
Duration (months): 24.0
Total project cost (EUR): 193594.8
EU funding (EUR): 193594.8
Participants: 1
Project status: CLOSED

A few years ago, the host laboratory has started a new project based on Memory of Chirality and dynamic axial chirality of tertiary aromatic amides and developed a new asymmetric synthesis of quaternary alpha-amino acids by using only the chirality of starting tertiary alpha-amino acid. The host laboratory is also currently working on the development of a new synthesis of enantioenriched non proteinogenic tertiary alpha-amino acid starting from achiral compounds (glycine and aromatic acid) and based on frozen chirality. The good results obtained encouraged them to pursue in this field. The current project consists in further extensions of these methodologies. This project is a great challenge because it is very original in terms of asymmetric synthesis, and in case of success, it would lead to the achievement of absolute asymmetric synthesis of tertiary alpha-amino acids. First, the projects plans to modify the substrates (to improve if possible the results) and then to extend these methodologies to other electrophiles in order to obtain functionalized quaternary or tertiary alpha-amino acids by aldolisation and conjugate addition. Another extension would be the application to the asymmetric synthesis of biologically active compounds, sphingophungines . Finally, the project plans to use the host laboratory expertise in the synthesis of oxazolidinone with external axial chirality to produce new chiral ligands and use them in asymmetric catalysis.

Keywords: organic chemistry,amino acids,chirality,asymmetric synthesis,memory of chirality,frozen chirality,dynamic axial chirality,asymmetric catalysis,chiral ligand
Global mapping of aerosol properties using neural network inversions of ground and satellite based data (AEROMAP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Greece
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-03-01
End date: 2014-02-28
Duration (months): 24.0
Total project cost (EUR): 222483.6
EU funding (EUR): 222483.6
Participants: 1
Project status: CLOSED

This project, AEROMAP, is designed to produce accurate, daily-updated, global atmospheric aerosol maps. To achieve this, AEROMAP will use the daily, full-Earth coverage of the aerosol optical depth (AOD) provided by the MODerate resolution Imaging Spectrometer (MODIS) satellite instrument in 3 wavelength bands (438-448nm, 673-683nm, 862-877nm), to extrapolate local, ground-based retrievals of aerosol microphysical properties (AMP) from AEROsol robotic NETwork (AERONET) stations to the entire Earth-surface. Extrapolation will be achieved with multiple-input multiple-output universal function-approximating artificial neural networks that will be trained on AERONET data (the AOD at 440nm, 675nm and 870nm) as input and AERONET-AMP retrievals (the aerosol size distribution, the complex refractive index, the effective radius, and the single scattering albedo) as output, in order to learn the inversion function. A portion of the training dataset will be reserved for validation. In the second step, MODIS broad-band AOD data that is spatially co-located with AERONET single-wavelength AOD data will be used to train a second neural network to learn the mathematical relationship between the broad-band and single-wavelength measurements. Then, the worldwide, daily coverage provided by MODIS will be used extrapolate and retrieve the sought-after AMP worldwide. Modern statistical methods of cluster analysis will be used to classify aerosol type regions and global maps of AMP will be used to provide a new full-Earth (near) real-time monitor to globally characterise atmospheric aerosols. Aerosol dispersal during selected events will test the validity of the monitor and a project website/portal will provide users access to global AMP maps, raw data and early-warning alerts of extreme aerosol conditions worldwide.

Keywords: aerosols (climate change),remote sensing (climate change),climate modelling (climate change),ozone and atmospheric composition
Evolving landscape of neuroendocrine tumor disease: Predicting tumor behaviour using metabolic profiling (METABONOMICS IN NETS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-05-01
End date: 2014-04-30
Duration (months): 24.0
Total project cost (EUR): 209033.4
EU funding (EUR): 209033.4
Participants: 1
Project status: CLOSED

Background: Tumors that arise from neuroendocrine cells (NENs) were traditionally considered rare tumors with low malignant potential. Recent data suggest that the incidence of NENs has increased over the last three decades. Furthermore, symptoms are frequently overlooked and subsequently, 60-80% of these tumors present with metastases at initial diagnosis. The common denominator of these tumors is their neuroendocrine origin; however, they demonstrate remarkable diversity, unique properties and different survival rates. We have little knowledge regarding the fundamental regulators of proliferation of these tumors and, hence, we have a narrow range of treatment options. We need additional biological and molecular data to enhance our knowledge on NENs, optimize patient stratification according to prognosis and to develop a more successful treatment strategy. Metabonomics is an emerging research field that provides an insight into the metabolic pathways of living cells. It represents a promising tool for better understanding of genetic data, for establishing a “metabolic signature” and for interpreting epidemiology in the cell level by metabolic screening. Aim: The aim of this study is to develop a metabolic signature of NENs that would allow stratification according to the primary tumor site and the malignant potential. We will also try to investigate the reported increase of NENs incidence. Methods: Patients with neuroendocrine tumors will be included in the study. Spectroscopy and spectrometry techniques will be used for the development of a metabonomic profile. Relevance to the work programme: This project will allow the experienced researcher to attain a higher level of training in the management of NENs and to be exposed to the field of metabonomics. The expected impact of the acquired additional skills and knowledge for the researcher is to enhance his academic profile and strengthen his ability to obtain an academic post in the country of his origin.

Keywords: neuroendocrine tumors,prognostic factors,stratification for treatment,impact of metabonomics on clinical practice
The Dark Energy Imprint on the Baryon Acoustic Oscillations (DEBAO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2013-03-28
End date: 2016-04-26
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 2
Project status: CLOSED

This work programme addresses pressing issues in both observational and theoretical cosmology. The main goal is to use the Baryon Acoustic Scale of Oscillations (BAO) to pin down the nature of the Dark Energy (DE) component. The BAO scale is a powerful probe of DE properties. It constrains geometrical as well as dynamical tracers of the Universe’s evolution, and can break the long-standing degeneracy between dark energy and spatial curvature. The observational component is strongly related to data analysis of the SDSS survey the most successful of astronomical surveys in history, in particular the BOSS survey that Dr. Cortes is a part of. It is also related to the design and conceptual planning of BOSS’s next-generation experiment, the GROUND-BASED SPECTROSCOPIC BigBOSS survey that Dr. Cortes is also a part of. BigBOSS is currently being planned at Dr. Cortês’ institution, Lawrence Berkeley National Laboratory and will extend the studies of BOSS to even earlier stages in the history of the universe, leveraging the full power of BAO to the next level. The theoretical component will play an essential role in ensuring the design of future probes of DE is optimized to obtain the best leverage of future data in the constraining of DE models. This work constitutes a breakthrough in the way BAO data, in particular from the Lyman-Alpha Forest, is currently treated and converted in constraints on DE. The goal of the project is to promote the transfer of expertise of analysis of BAO data between the US and the European Union, through the EDINBURGH INSTITUTE FOR ASTRONOMY. It is also highly beneficial for European Science Community as a whole to exchange expertize in survey planning with the US, in consultation with community-led teams to define the optimal survey with a broad and rich science yield.

Keywords: physical sciences,cosmology,dark energy
Intersectional Contract. Understanding the Intersection of Gender and “Race”/Ethnic Inequalities in the Care-Domestic Sector in the UK by Means of Racial-Sexual Contract Analysis (INTERSECTINGCONTRACT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2013-10-01
End date: 2015-11-12
Duration (months): 24.0
Total project cost (EUR): 209033.4
EU funding (EUR): 209033.4
Participants: 2
Project status: CLOSED

The 2007 EC Report “Tackling Multiple Discrimination” addressed for the first time at the EU level the issue of intersectionality, an approach that seeks to understand several forms of discrimination (based on gender, “race”/ethnicity, class and so forth) as the results of intersecting biases rather than of single sources of inequality. This represents a significant step towards increasing awareness of the interrelation of different types of discrimination, enabling policy makers to tackle it in a more effective manner. This research project, using an interdisciplinary approach that combines intersectionality theory and “racial-sexual contract” analysis, aims to contribute to this debate by focusing on gender and “race”/ethnicity biases in the care-domestic labour sector in the UK. It is of the greatest importance to consider the combined impact of gender and “racial”/ethnic factors on a labour market that has witnessed dramatic growth in the participation of women of ethnic minority background across all EU Member States in recent years. The study of the care-domestic sector in the UK is of particular interest due to the more advanced and articulated character of this phenomenon in the UK, and the responses it has elicited on both the policy and theoretical level. The research project introduces the new concept of “intersectional contract” and operationalizes it for empirical research. A mixed-method approach is employed, including the gathering of quantitative data, qualitative in-depth interviews with key actors (domestic placement agencies’ owners, employers, employees and policy makers), and critical discourse analysis of regulations and policy documents. This research project will consolidate the researcher’s profile as an expert sociologist of gender and migration, enable the acquisition of new competencies and interdisciplinary skills and position the researcher as a leading scholar of themes of current dramatic socio-economic relevance.
Innovations in Fluvial Environmental Research: Core Scanning of Flood and Contaminant Histories (INFER)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ireland
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-06-01
End date: 2014-05-31
Duration (months): 24.0
Total project cost (EUR): 191938.2
EU funding (EUR): 191938.2
Participants: 1
Project status: CLOSED

River floodplain sediments can provide valuable information on climate, land-use and pollution histories that can support sustainable river management objectives. In this project, the applicant will use a unique collection of state-of-the-art analytical technologies at University College Dublin, Ireland, to develop and test approaches for unlocking these floodplain sediment archives in an holistic and novel manner. At the centre of the project is the application of micro-XRF core scanning which permits rapid, non-destructive chemical analysis of sediments at sub-mm resolutions. These new technologies, that have the potential to revolutionise geochemical research and applications in floodplain environments, will be tested against complementary geochemical and high resolution imaging techniques for the purpose of reconstructing (i) contaminant heavy metal concentrations and (ii) flooding histories in Irish and UK catchments. The candidate will gain technical skills in the preparation and analysis of samples, together with training in environmental geochemistry, cutting edge high resolution image analysis and statistics that will complement her understanding of fluvial geomorphology and sedimentology. Furthermore, through an established Performance Management Development System at the host institution, a programme of training will provide the applicant with opportunities to enhance her teaching and project management skills and gain instruction and experience in research writing, presentation and supervision that will leave her exceptionally well-placed to pursue an academic career. The innovative research required to fulfil the project’s objectives will enhance excellence and knowledge transfer within the European Research Area by providing guidance for future research in the field, while furthering river management policy objectives that are currently being pursued by EU member states under the Floods Directive (2007/60/EC) and Water Framework Directive (2000/60/EC).

Keywords: physical geography,geochemistry,hydrology,floods,geomorphology,sedimentology
Poverty in the Face of Conflict (POVCON)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-05-21
End date: 2014-05-20
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 1
Project status: CLOSED

Violent conflict has been identified as one of the most important constraints to poverty reduction and the promotion of economic development and democracy worldwide, especially in areas characterized by persistent violence and fragile institutions. The main objective of this project is to ascertain how the presence of armed conflict affects the capacity of households to cope with income shocks and uncertainty. It will investigate the relationship between vulnerability to poverty, violent conflict and household welfare in the context of the Maoist insurrection in India. The project will use data from the Young Lives project in Andhra Pradesh, the National Sample Survey, and new event data on the Maoist conflict. It first examines which types of idiosyncratic and covariate shocks affect household welfare, and how households respond to these. It will then explicitly incorporate Maoist violence in the analysis, and studies the impact of the movement on households’ ability to insure against and cope with adverse shocks identified in the first step. Finally, the distributive effect of the Maoist movement in Andhra Pradesh will be studied. This will yield important information about the dynamics of the conflict. The project represents one of the first micro-empirical attempts to link two important strands in recent development economics research: research on the relationship between economic shocks and household welfare, and research on the welfare consequences of conflict and violence. This knowledge is crucial for the design and implementation of safety nets and insurance schemes, as well as leading to important lessons on how to deal with conflict impacts at the household level. It will contribute to the state of the art of modern development economics by investigating the impact of persistent, low-level conflict. It will also advance substantially our knowledge of the mechanisms of insurgencies founded on ideological aims.

Keywords: development,conflict,security,poverty,economics,vulnerability,risk,uncertainty,coping