Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Theoretical basis for the design of Lanthanide-based molecular nanomagnets (4FNANOMAG)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-05-15
End date: 2010-05-14
Duration (months): 24.0
Total project cost (EUR): 154821.03
EU funding (EUR): 154821.03
Participants: 1
Project status: CLOSED

The design of molecular nanoscale magnets is a hot topic research area due to their technological interest in high density data storage or quantum computing. In this field, lanthanide-containing systems are appealing due to the large magnetic moment and large anisotropy associated with most of the lanthanides, key factors determining the temperature below which single-molecule(SMMs) and single-chain magnets(SCMs) retain the magnetization due to its slow relaxation. Whereas 3d-based molecular nanomagnets have been largely studied and their relaxation mechanisms are well understood, little is known for their novel 4f-based counterparts. For this reason, the aim of this project is to fulfill this lack of knowledge in order to support a future rational design of 4f-based nanomagnets for technological applications. For that, several theoretical methods will be employed: Quantum Chemistry methods for computing the Stark sublevels of the lanthanide ions, theoretical models for describing the dynamics of the magnetization in 4f-based nanomagnets and statistical physic methods for modeling the behaviour of the 4f-based SCMs. Moreover, X-ray, spectroscopic and magnetic measurements will be needed in order to provide suitable experimental data for developing and testing the theoretical studies. Due to the profile of the project, LAMM laboratory, one of the world leader laboratories in molecular magnetism, is the ideal place for its accomplishment because the large experience in molecular synthesis, including lanthanide chemistry, and the expertise in combining theory and experiment in the study of molecular-based magnets, in particular in SMMs and SCMs. Finally, the realization of the project will complement the theoretical and experimental expertise of the applicant in order to develop an independent career in theoretical aspects of molecular magnetism and it will afford him to establish contacts with other European research groups for future collaborations.

Keywords: nanosystems,electronic,magnetic and superconductive properties,molecular magnetism,single molecule magnets,nanomagnets,lanthanide-based compounds,computational chemistry,statistical physics
Building a regulatory network for lateral root emergence (EMERGENCE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-08-01
End date: 2010-07-31
Duration (months): 24.0
Total project cost (EUR): 178307.05
EU funding (EUR): 178307.05
Participants: 1
Project status: CLOSED

Cell separation is a critical process for plants. Germinating seedlings emerge from their seed coats, anthers dehisce, fruit ripen, and organs are shed as a result of plant cell separation. To date, several cell wall remodeling enzymes associated with cell separation have been identified, however very little is known about the signals and mechanisms controlling their expression. The host laboratory has recently made major advances in the identification of the signals and molecular mechanisms regulating cell separation during lateral root emergence. The auxin influx transporter LAX3 allows the auxin inducible expression of a set of cell wall remodeling genes in front of the lateral root primordium to promote cell separation. The expression of these genes is dependant on the AUX/IAA proteins SLR1 and SHY2. The main aim of the present project is to study the signals and regulatory network that coordinates plant cell separation employing lateral root emergence as a model. I propose to adopt a Multidisciplinary Integrative Biology based approach which takes advantage of the facilities and expertise available in the host laboratory. Functional genomic, chemical genetic and mathematical modeling approaches will allow to identify new regulatory components and target genes then to build a regulatory network that will be modeled and tested.

Keywords: plant development,auxin influx,lateral root emergence,regulatory network,lax3,cell separation
Identification of novel protein kinases required for meiosis (NPKM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-06-01
End date: 2010-05-31
Duration (months): 24.0
Total project cost (EUR): 167393.24
EU funding (EUR): 167393.24
Participants: 1
Project status: CLOSED

During meiosis, one round of DNA replication is followed by two rounds of cell division. This results in production of four haploid cells from a diploid precursor. Proteins required for this reduction of chromosome number are largely unknown. In this project, we want to identify novel proteins required for meiotic chromosome segregation. Protein kinases are the key cellular regulators and some of them are known to be essential for proper segregation of chromosomes during meiosis. We now want to look at protein kinases essential for mitotic growth and identify those required for chromosome segregation during meiosis. We want to take advantage of chemical genetics and construct conditional alleles of protein kinases sensitive to small molecule inhibitors (analog sensitive alleles). We want to use these alleles to determine which of protein kinases essential for mitotic growth are required for chromosome segregation during meiosis.

Keywords: kinase,meiosis,s. pombe,chromosome segregation,mono-orientation,knock-outs
Environmnental stresses in a scleractinian coral-dinoflagellate symbiosis: a genomics approach (ESCOR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2007-4-1-IOF, 2007)
Start date: 2008-09-01
End date: 2011-08-31
Duration (months): 36.0
Total project cost (EUR): 230256.08
EU funding (EUR): 230256.08
Participants: 1
Project status: CLOSED

The continued development of M. Pernice as an independent researcher in marine science ultimately depends on his building a strong scientific background and a network of colleagues who are both international in representation and have multidisciplinary expertise. Pursuing a fellowship with an Outgoing phase in the Centre for Marine Studies (Australia) and Return phase in the UMR 5178 (France) offers the unique opportunity to create such a synergy between the experience in research on both climate change and symbiosis. The great success of corals as ecosystem engineers lie in their extraordinary ecology and physiology that is based on a mutualistic symbiosis between a photosynthetic dinoflagellate algae (zooxanthellae) and the anthozoan animal host. Within the last several decades, scleractinarian corals have been affected by the phenomenon of mass coral bleaching, caused by the breakdown of the symbiosis between the cnidarian host and the photosynthetic symbiont and undergo a continuous global degradation in relation to global climate change. For the first time, this project proposes to specify the effects of elevated temperature and ultraviolet light on the transcriptome of the symbiotic complex between the coral Acropora millepora and the zooxanthellae Symbiodinium sp. The effects of environmental stress on both host and symbiont genes’ expression will be characterised by using cDNA microarray, RT-PCR and Fluorescent In Situ Hybridization technics. By facilitating a multidisciplinary integrated approach (Climate change, Marine sciences, Physiology, Genomics) of the study of the marine organisms and their ecosystems, this study will enhance considerably the scientific excellence of the fellow at an international level. The postdoctoral training delivered by this project will ensure that a promising young European researcher is supported and develops futher technical skills and experience to study the impact of global climate change on coral reef ecosystems.

Keywords: climate change,coral reefs,genomics,marine sciences,physiology,symbiosis
Nanostructured Mesoporous Coatings of Implant Materials for Improved Bone Formation (MESO-IMPLANT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-12-01
End date: 2010-11-30
Duration (months): 24.0
Total project cost (EUR): 168823.92
EU funding (EUR): 168823.92
Participants: 1
Project status: CLOSED

The MESO-IMPLANT project was inspired by the most recent achievements in nanotechnology and regenerative medicine and has two major objectives. The first one is based on the original idea of using the thin films of ordered mesoporous materials as coatings for bone implants. Such coatings have extremely high specific surface areas and pore volumes and are aimed to significantly improve the speed of bone formation on their surface. This would allow to lower the implant fixation time and to lower the probability of implant failure. The applicant will synthesize ordered mesoporous thin films of various metal oxides (eg. titania, alumina) and test how they can improve bone formation. The latter will be performed by direct contact of such layers with bone forming cells (osteoblasts) and observation of their bone forming activity (eg. under optical microscope). Additionally, the mesopore system will be functionalized with bioactive molecules which can mediate osteoblast adhesion process as well as to control the differentiation of the adult stem cells. Successful results of this project may open new research areas both in academia and in industry. The second aim of this project is to give the high-end interdisciplinary training-through-research in nanobiotechnology and nanomedice to the applicant. His background is chemistry and nanomaterials and through this project he will have an unrivalled opportunity to develop his skills in bionanotechnology with help of the leading scientists in the filed. Moreover, he will have a chance to work in the highly multidisciplinary environment at one of the top universities in the world.

Keywords: nanotechnology,nanobiotechnology,biomaterial engineering,mesoporous materials,mcm-41,thin films
Revising the Role of Groundwater in Life Cycle Assessment (GWAT-LCA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-02-15
End date: 2010-02-14
Duration (months): 24.0
Total project cost (EUR): 178927.59
EU funding (EUR): 178927.59
Participants: 1
Project status: CLOSED

Life Cycle Assessment (LCA) is the standardised method for assessing the environmental impacts of any product or service. After quantifying all associated emissions and the consumption of resources, this impact is expressed with respect to a few common impact categories. These are supposed to reflect major societal and environmental priorities. Although groundwater is the most extracted raw material in the world, and extraordinarily important for most parts of the EU, it is virtually ignored in LCA. To overcome this deficiency, an interdisciplinary approach is needed. The proposed fellowship integrates a hydrogeologist into a prominent group of LCA experts, in order to develop the initial steps for tackling groundwater quality and quantity issues within an LCA framework. The fellow is offered extensive training on LCA concepts to combine the perspectives of both LCA expert and hydrogeologist. The research work includes a general gradation of threats to groundwater and the development of a competent modelling framework. The latter task is dedicated to the improvement and consistent development of modelling tools. This is to enable a balanced simulation of different hydrogeological threats, and to uniformly account for the spatial variability of environmental conditions. A major focus is placed on the issues of whether, and how, groundwater can be considered a safeguard object within impact assessment, assumed that it represents a separate receptor. The scientific results of this project are expected to be fundamental but still incomplete in achieving a generally valid methodology, which complies with the holistic requirements of LCA practice. However, it will be a necessary starting point for revealing the principal relationships between LCA and hydrogeology and ultimately defining the research needs in this highly timely subject. For the fellow, the profound thematic and social expertise gained will be ideally suited to a novel and ambitious field of science.

Keywords: life cycle assessment,groundwater,hydrogeology,hydrology,integrated management of water,environmental impact
Are fungal spores perfect projectiles? Evolution of ascospore shape. (AFSPPEOAS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2007-4-1-IOF, 2007)
Start date: 2008-05-05
End date: 2011-11-04
Duration (months): 36.0
Total project cost (EUR): 251102.11
EU funding (EUR): 251102.11
Participants: 1
Project status: CLOSED

Fungi are important components of our ecosystem since they both provide nutrition for many animals and are major recyclers of minerals and carbon. However, many fungi are parasites on plants, animals and other fungi. Serious fungal pathogens of cultivated plants cause extensive damage and losses to agriculture and forestry. The very common species usually found in pillows cause one of the most dangerous mortal infections in persons with immuno-deficiencies. Fungi reproduction results in almost-indestructible spores, which are the major carrier of diseases. In many cases the spores are forcibly ejected clear of the parental fungus. The probability of the species to survive depends upon spores germinating far from the fruiting body where they are formed. Fungi achieve very large launch velocities, applying initial accelerations that are unmatched in the plant or animal kingdoms. Fungal-spores must minimize the air-resistance, which is the prime determinant of their range (it can deplete the launch velocity of as much as 99.997%). Can we set the shape of a “perfect projectile”? How can a spore be shaped to minimize drag, if it has never experienced air resistance? In the first part of the project we study theoretically, numerically and experimentally the fluid mechanics of spore ejection. The second part inquires into the developmental process of spore shape theoretically and experimentally. The general idea is that evolution has selected the minimum-drag shape for spore survival. We plan to observe the formation of the spores inside Neurospora tetrasperma, one of the most studied model organisms of biology.

Keywords: hydrodynamics,cell biology,mycology,fungal pathogens,selective evolution,sporulation
Array of coupled nanoresonators (ACRES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark
Call:  (FP7-PEOPLE-2007-4-1-IOF, 2007)
Start date: 2009-04-01
End date: 2013-04-15
Duration (months): 36.0
Total project cost (EUR): 258341.24
EU funding (EUR): 258341.24
Participants: 1
Project status: CLOSED

A novel system based on NEMS resonators will be developed. An array of coupled nanoresonators with a transduction based in the strain of thin layers of metal will be developed. To do that, analytical studies, FEM simulations, design and fabrication will be performed. The characterization will be done in three steps: measure frequency response of the system and characterization of the mass sensitivity (outgoing phase) and its use as a biosensor (return phase).

Keywords: nanodevices,nanosystems,high frequency technology
Forming of aluminum alloys at elevated temperature (FALET-HL-CEMUC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Portugal
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-07-01
End date: 2009-06-30
Duration (months): 12.0
Total project cost (EUR): 64095.3
EU funding (EUR): 64095.3
Participants: 1
Project status: CLOSED

This proposal of Intra-European fellowships deals with the joint proposal between Dr H. LAURENT of “Laboratoire de Génie Mécanique et Matériaux” of “Université de Bretagne-Sud” (UBS-LG2M) in France and Professor L.P Menezes of the “Centro de Engenharia Mecanica" of "Faculdade de Ciências e tecnologia da Universidade de Coimbrada” (FCTUC-CEMUC) in Portugal. The aim of this project is to reinforce research between our two laboratories in the domain of sheet metal forming and to give opportunities to Dr. H. LAURENT to develop his research training project. The objective is to put in common the potentialities of laboratories in the knowledge of the formability of aluminium alloys at elevated temperatures. The Unit research CEMUC has been part of a Mundial project of “Digital Die Design – 3DS – IMS” and has achieved an European dimension notoriety beside research laboratories and manufacturers. The project of researcher Dr LAURENT, during the years 2008-2009 in the University of Coimbra, is to improve his knowledge in the experimental and numerical studies in metal forming. This advanced training will provide the means to significantly advances in his career and give him the possibility to obtain the title of Professor in France. This collaboration leads to publish common works in several journals and international conferences. The aim of this study is to investigate the springback of aluminium alloy sheet during warm deep-drawing process. We shall compare several phenomenological models of elastoplasticity and model of elasto-visco-hysteresis for the prediction of springback for the deep drawing of aluminium alloy. Experimental springback ring tests (Demeri’s test) will be performed to measure material deformation and displacement during cup forming, ring trimming and springback after ring splitting. Several numerical models with commercial and laboratory codes will be used to show the influence of behavior law in the prediction of springback.

Keywords: mechanical engineering,materials engineering,computer-aided manufacturing,metal technology
Expanding the Potential of in vitro Compartmentalised Screening and Selection Approaches (EXIVC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2007-4-2-IIF, 2007)
Start date: 2008-03-01
End date: 2010-02-28
Duration (months): 24.0
Total project cost (EUR): 178874.06
EU funding (EUR): 178874.06
Participants: 1
Project status: CLOSED

In vitro selections offer the potential to select from large libraries, with fewer constraints than current cell-based selections. The key practical consideration in directed evolution of functional biomolecules is the linkage of genotype and phenotype, which can be provided by water-in-oil emulsion droplets that act as femtolitre reactors. Novel applications for catalytic selections of cellulases, key enzyme in teh production of bio-fuels, will be developed by in vitro compartmentalisation techniques in microfluidic devices that the host group has recently developed.

Keywords: molecular evolution,biomedical engineering
Fostering Regional Innovation and Development through Anchors and Networks: A Cross Regional Comparison in an Evolving International Context (FRIDA)

Framework: FP7 — Cooperation
Programme: Socio-economic sciences and Humanities
Destination: Combining economic, social and environmental objectives in a European perspective
Action type: Collaborative project
Countries involved: Italy,Germany,France,Poland,United Kingdom,Italy,Ukraine,Germany
Call:  (FP7-SSH-2007-1, 2007)
Start date: 2009-01-01
End date: 2011-03-31
Duration (months): 27.0
Total project cost (EUR): 1576888.0
EU funding (EUR): 1273977.0
Participants: 9
Project status: CLOSED

The FRIDA (‘Fostering Regional Innovation and Development through Anchors and Networks’) project aims to improve regional policy making within the EU, by advancing state of the art understanding of the importance of anchor firms to regional development and cohesion. Anchor firms are known to be increasingly important to regional development as highly entrepreneurial, multi-national firms restructure and relocate in response to the pressures of globalisation. However, there is currently a substantial gap in our understanding of the reasons for their qualitatively different impacts on different regions, how and why they assist the development of networks and capabilities in regions, and what local policies make particular regions attractive, and influence anchor firms to contribute towards more cohesion and even development. By addressing these questions, the FRIDA project aims to both improve understanding and contribute towards the effectiveness of policy making. The outputs of the project are designed to directly help regional policy-making to better anticipate and respond to economic restructuring by helping create regional governance systems that ensure less developed regions level-up to the most developed regions, rather than more developed regions levelling-down in response to the increasing freedom of movement of capital, production and knowledge. In doing so, the project aims to directly address the main points in the call and improve development throughout Europe in a way that is more sustainable, even and socially cohesive.

Keywords: regional development,clusters,networks,performance