Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Discovering Fast Transients and Pulsars with MeerKAT for Cosmology and to Test the Laws of Gravity (MeerTRAP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-10-01
End date: 2022-09-30
Duration (months): 72.0
Total project cost (EUR): 3488955.91
EU funding (EUR): 3488955.91
Participants: 1
Project status: SIGNED

Short duration bursts of cosmic radio emission provide us with a potent tool for studying the extremes of physics. In the form of periodic pulses from pulsars they can be used as precision instruments to test theories of gravity, understand the emission processes and the equation of state of ultra-dense matter. In the form of transient bursts we can use them to study the physics governing explosive events such as gamma-ray bursts, merging neutron stars, annihilating black holes or hitherto unknown phenomena. Observing how these bursts are affected by their passage through the distant Universe allows us to probe its physical state. To harness the combined power of periodic and bursting radio sources to explore physics beyond that possible in a terrestrial laboratory I propose MeerTRAP: Meer (more) TRAnsients and Pulsars, a project to continuously use the MeerKAT telescope to search the radio sky for pulsars and fast transients and to rapidly and accurately locate them. Utilising the excellent sensitivity and sky coverage of MeerTRAP my team will discover many rare and scientifically important pulsar types: relativistic binaries, intermittent emitters, transitioning systems. Current radio telescopes have only explored the tip of the transients "iceberg" and MeerTRAP will transform our knowledge of these manifestations of extreme physics. It will detect hundreds of new bursts, which will all be well localised, allowing us to identify hosts and distances, greatly enhancing their use as cosmological probes. Localisation also enables measurement of their true fluxes, polarisation and spectral indices which are all crucial to identify their origin. To achieve this we will design, implement and exploit state-of-the-art hardware and software. We will also use the MeerLICHT optical telescope, which will track MeerKAT, to give us a crucial glimpse of the optical sky immediately before and after any radio transient to further constrain their origin and the associated physics.

Keywords: pulsars,fast radio bursts,high performance computing,radio astronomy
Off The Rails (OTR)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: United Kingdom
Call: Small business innovation research for Transport (H2020-SMEINST-1-2014, 2014)
Start date: 2014-10-01
End date: 2015-02-28
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Off the Rails is a concept to develop a mobile application that intelligently understands user movement patterns, not just in terms of location, speed and transport mode. Utilising smart-phone sensors, GPS mapping and game mechanics, it will give the user the vectored detail of their daily travels. The unique concept is being developed in the context of Mudlark’s world-leading digital public transport game, Chromaroma, which turns all swipes of a player’s London travel smartcard into gameplays and achievements, promoting sustainable transport use by encouraging non-rush hour travel. The advent and increasing accuracy of geolocation data harnessed with the prevalence of powerful personal mobile devices means we use OTR to make the individual traveller a transport integrator. We can build a platform that attracts these solo integrators and retains them by improving their travel experience, at the same time capturing individual journey data. That platform can then flip the transport integration problem by addressing it from the user level up. By combining and transferring new and existing knowledge into an innovative, disruptive and competitive solution, we will enhance the profitability and growth performance of Mudlark (an SME). We need the funding from this grant to help seize the European and global business opportunity. As well furthering our understanding the commercial case, our project objectives are to: ● Discover and understand the user needs. This will culminate in a framework and design scoping document. ● Test initial technical and tracking assumptions with an end-user group. ● Design the user experience and game using screen and paper prototypes. ● Produce a detailed report, game design document and business planning roadmap. We will conduct a variety of analyses to confirm the viability of our game and justify further external investment, specifically Phase 2 funding from this programme.

Keywords: transport integration,mobility,geolocation,multi modal,gamefication
Action Leveraging Evidence to Reduce perinatal morTality and morbidity in sub-Saharan Africa (ALERT)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Health care provision and integrated care
Action type: Research and Innovation actions
Countries involved: Germany,Uganda,Belgium,Tanzania, United Republic of,Sweden,Pakistan,Malawi,Benin
Call: Implementation research for maternal and child health (H2020-SC1-2019-Two-Stage-RTD, 2019)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 3999976.25
EU funding (EUR): 3999976.25
Participants: 8
Project status: SIGNED

Insufficient reductions in maternal and neonatal deaths and stillbirths in the past decade are a threat to achieving the Sustainable Development Goal 3. Overcoming the knowledge-do gap to ensure implementation of known evidence-based intervention during the intrapartum period – the period from onset of labour to immediately after childbirth – has the potential to avert at least 2.5 million deaths in mothers and their offspring annually. Our ALERT approach targets this period and will develop and evaluate a multifaceted health system intervention to strengthen the implementation of evidence-based interventions and responsive care in Sub-Saharan African hospitals, where 40-50% of all births in the region take place. The ALERT intervention will include four main components: i) end-user participation through narratives of women, families and midwifery providers to ensure co-design of the intervention; ii) competency-based training; iii) quality improvement, supported by data from a clinical perinatal e-registry; iv) empowerment and leadership mentoring of maternity unit leaders complemented by district based bi-annual coordination and accountability meetings. We will apply a gender lens to explore constraints in intrapartum care in the context of the multidisciplinary teams providing maternity care. Repositioning midwifery with its preventive, promotive and curative aspects is a cross-cutting theme. We will evaluate the intervention through a stepped-wedge design, the primary outcome being in-facility perinatal (stillbirths and early neonatal) mortality. Our nested realist process evaluation will help to understand what works, for whom and under which condition. An economic evaluation will report on scalability and costs. Our research aims to inform programming for the Sustainable Development Goals and Every Women Every Child Agendas of the United Nations to support Universal Health Coverage and patient-centred care which will be relevant beyond the project focus

Keywords: midwifery,health system intervention,sub saharan africa,hospital
FAIRshare. Farm Advisory digital Innovation tools Realised and Shared (FAIRshare)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Coordination and support actions
Countries involved: Austria,Spain,Germany,Germany,Spain,Spain,Germany,Ireland,Italy,Ireland,Belgium,Croatia,Lithuania,Switzerland,Greece,Hungary,Poland,Poland,Slovenia,Norway,Belgium,Belgium,Belgium,Finland,Croatia,Serbia,Latvia,France,France,France,France,France,France,Netherlands,Netherlands,United Kingdom,Denmark,Denmark,Portugal,Portugal
Call: Enabling the farm advisor community to prepare farmers for the digital age (H2020-RUR-2018-1, 2018)
Start date: 2018-11-01
End date: 2023-10-31
Duration (months): 60.0
Total project cost (EUR): 6998652.5
EU funding (EUR): 6998652.5
Participants: 47
Project status: SIGNED

Electronic data generation, analytics and communication technologies potentially enable more accurate, faster and better decision-making on farms, with huge potential to improve agricultural sustainability. There is a major focus on digitisation by EU and national/regional policy-makers to ensure that digital innovation in agriculture keeps pace with other sectors and the benefits of digitisation are available to the wider farming community. However, there is a danger that digitisation and future innovations will be hampered unless the rural advisory community is mobilised to take ownership of digital tools and to advocate at the user interface. This CSA will engage, enable and empower the independent farm advisor community, through sharing of tools, expertise and motivations. FAIRshare has two main programmes. Firstly, WPs 1, 2 and 3 will gather an evidence base of the digital tools and services used internationally, leveraging the social networks of partner institutions that span EU and non-EU countries. The inventory of tools will be accessible to end-users on an intuitively navigable online interface that has been co-designed using a multi-actor approach. Accompanying the tools in the online inventory will be information, for instance short ‘good practice’ vignettes, on how the tools may be used/adapted for use. Secondly, WPs 4, 5 and 6 will generate and resource a participatory ‘living laboratory’, empowering advisor peers from across the EU to interact with the online inventory and, in a series of workshops, to exchange, co-adapt, co-design and apply digital tools. The FAIRshare 'living lab’ will enable advisors to address challenges to embedding digital tools in different advisory and farming contexts across the EU. Special focus will be on co-designing powerful communication and engagement approaches for advisors to advocate and inspire their peers and farmer clients, driving a social movement for the wider and better use of digital tools.

Keywords: agriculture,precision agriculture,digital social innovation
Photocatalytic Deracemisation of Amines (PhotoDeRac)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United States,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-07-01
End date: 2023-04-02
Duration (months): 30.0
Total project cost (EUR): 230416.32
EU funding (EUR): 230416.32
Participants: 2
Project status: SIGNED

A method is proposed for the deracemisation of tertiary amines via the joint action of three distinct molecular catalysts - an Ir(III) photocatalyst, a chiral Brønsted base and a chiral thiol hydrogen-atom transfer additive. Through sequential visible-light driven electron transfer (ET), proton transfer (PT) and hydrogen-atom transfer (HAT), proximal stereocentres to amine functional groups can be selectively targeted for destruction of the undesired substrate enantiomer, and restored as the desired. An optical enrichment in the amine sample then builds over time, without other chemical change taking place. The two separate chiral catalysts work in tandem on two mechanistically distinct elementary steps, resulting in an amplification of asymmetric induction. Initial substrate activation is non-stereoselective, meaning that the total amount of substrate is capable of being processed, in stark contrast to typical chemical resolution methods. The method requires no stoichiometric reagents, produces no stoichiometric waste, is redox-neutral, and consumes only visible light photos. We believe this method will be of direct utility to the synthetic organic and medicinal chemistry communities, offering more efficient and more sustainable synthetic routes to target molecules, and going beyond the existing state-of-the-art. In the return phase of the project, the method is extended to the control of amine substrate diastereoisomers, in a tandem process involving C–N bond formation. Through appropriate catalyst selection we aim to develop complimentary methods to access either the thermodynamic or kinetic isomer – something difficult to achieve with existing epimerisation protocols. The concepts introduced here address fundamental questions of absolute and relative stereocontrol, retrosynthetic design, asymmetric autocatalysis and the utility of light as a driver of chemical change against a thermodynamic gradient, to achieve an out-of-equilibrium product distribution.

Keywords: amines,deracemisation,sustainability
DynaTweezers: Elucidating the Molecular Mechanisms of Bacterial Gene Silencing using Tethered Particles and Optical Tweezing (DynaTweezers)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands,Canada
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2021-05-31
Duration (months): 36.0
Total project cost (EUR): 228421.8
EU funding (EUR): 228421.8
Participants: 2
Project status: CLOSED

Antimicrobial-resistance is a growing concern in modern medicine. The spread of antibiotic resistant genes, both within bacteria species and between species, is greatly accelerated by horizontal gene-transfer. In intestinal bacteria, a major pool of antimicrobial resistance, the impact of foreign acquired DNA is modulated by H-NS proteins that recognize and silence its expression. I propose to investigate the molecular mechanism of gene silencing by H-NS and related co-regulatory proteins at a single molecular level. With the understanding of the underlying mechanisms, we may enable the development of medicines that revert or suppress the expression of antimicrobial-resistant genes. I plan to investigate the silencing mechanism of H-NS using a combination of dynamic Tethered Particle Motion and axial Optical Tweezers. These techniques allow me to characterize the repeated transcription of individual DNA strands in high detail under a variety of external conditions and under applied forces. Using these techniques, I can systematically study how transcription is affected by stalling of the transcription complex, loop formation and promotor occlusion. My experience in biophysical measurement techniques, in combination with the high performance optical tweezer expertise and an established network of H-NS research in Toronto enable the proposed research in a unique and powerful way.

Keywords: dynamic tethered particle motion,axial optical tweezers,gene silencing,h ns proteins,transcription regulation,bacterial genomics,antimicrobial resistance,antibiotic resistance,rna polymerase
Centre of Excellence for Mathematical Modeling and Advanced Computing (MMAC)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Specific Grant agreement
Countries involved: Austria,Bulgaria
Call: Teaming (H2020-WIDESPREAD-2014-1, 2014)
Start date: 2015-06-01
End date: 2016-05-31
Duration (months): 12.0
Total project cost (EUR): 370300.0
EU funding (EUR): 370299.0
Participants: 3
Project status: CLOSED

The goal of the project is to present a long term vision for a new Centre of Excellence (CoE) for Mathematical Modeling and Advanced Computing in Science and Engineering and a business plan for its establishment. The founders of the center are the two leading scientific institutions in Bulgaria in the area of Mathematical Modeling and Advanced Computing – the Institute of Information and Communication Technologies (IICT) – coordinator, and the Institute of Mathematics and Informatics (IMI), both from the Bulgarian Academy of Sciences, jointly with the advanced partner Vienna University of Technology (TU Wien). The CoE will concentrate its activities in four carefully selected key areas with high potential for first-rate scientific achievements and innovations: (i) Mathematical Modeling; (ii) Advanced Computing; (iii) Content Technologies, Intelligent Interfaces and Knowledge Processing; (iv) Flagship Applications in Science and Engineering. They are primarily focused on scientific excellence and technology breakthroughs in priority directions aligned with the challenges of the Programme Horizon 2020 and the Bulgarian Innovation Strategy for Smart Specialization 2014-2020, especially the priorities "Informatics" and "ICT and Mechatronics and Green Technologies". The CoE will be supported by the e-infrastructure "National Centre for High Performance and Distributed Computing", which combines hardware, software, middleware, and services, coordinated by IICT. This infrastructure is a part of the Bulgarian National Road Map for Research Infrastructures. The CoE is aimed at developing new mathematical approaches and advanced computing tools for efficient solutions of problems with high scientific and social impact. The strong research and development potential and mutually complementary expertize of the two Bulgarian institutions, IICT and IMI, and the advanced teaming partner from TU Wien, fully meet the challenging requirements of the planned new truly joint center.

Keywords: mathematical modeling,advanced computing,content technologies,intelligent interfaces,knowledge processing,flagship applications,high performance computing infrastructure
Decontamination with Ice (ChillBact)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Iceland,France,France,Denmark
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2020)
Start date: 2020-10-01
End date: 2023-03-31
Duration (months): 30.0
Total project cost (EUR): 2542085.0
EU funding (EUR): 1965743.0
Participants: 6
Project status: SIGNED

Poultry production, the world ́s fastest growing meat sector, is facing serious problems because of the high incidence of food-borne diseases, lack of efficient cooling, ever-stricter food safety regulsation, and concerns about food waste and environmental impact. In Europe every year more than 9 million people are being infected by Campylobacter or other food bacteria. ThorIce’s new solution DeConIce shows promising results as a highly efficient cooling method and as a method for dramatic reduction of Campylobacter on chicken skin without using disinfectant chemicals, pharmaceuticals or soaps; but by using a unique combination of water and ice. It is slush-ice that cools down the chicken meat in the production. The project represents the whole value chain (research, technology provider, food industry and end-users), and is perfectly aligned to bring a completely new solution to market and ensure its cost-effective implementation into European poultry industry. The project’s objective is to finetune the technical parts of the DeConIce solution and conduct two “real-life full-scale demonstrators” at two poultry factories in France. The objective is also to secure an independent scientific and statistical analysis of the reduction of campylobacter level on chicken meat and make a risk analysis of its potential to reduce food poisoning in Europe. During the project ThorIce will update its business strategy and ramp-up production capacity to meet expected rise in demand. After completion of the FTI project, ThorIce will be well positioned to become the leading supplier of equipment for eco-friendly bacteria decontamination and chilling of poultry to the 4 major equipment suppliers to the poultry industry, Marel (IS), Meyn (NL), Baader-Linco (D) and FoodMate (US) which controls more than 80 % of the world market. With the FTI grant ThorIce can increase Speed to Market, which is vital, as there are more than 25 thousand people getting food infections every day in Europe.
Reliable Energy and Cost Efficient Traction system for Railway (RECET4Rail)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: European rail initiative
Action type: Research and Innovation actions
Partnership: Shift2Rail (Art-187)
Countries involved: Germany,Italy,Spain,Finland,Poland,Sweden,Belgium,France,France,France
Call: Support to Development of next generation of Traction systems (TD1.1) (H2020-S2RJU-OC-2020, 2020)
Start date: 2020-12-01
End date: 2023-09-30
Duration (months): 34.0
Total project cost (EUR): 2300036.25
EU funding (EUR): 2300036.25
Participants: 15
Project status: SIGNED

Rail is a fundamental service for modern societies and the backbone of a sustainable transport system. To meet the numerous challenges ahead, the global rail sector must increasingly rely on the emerging disruptive technologies such as advanced robotics, 3-D printing, high computing power and connectivity, etc. which are integrated with analytical and cognitive technologies that enable machine-to-machine and machine-to-human communication.On top comes the pressure to reduce energy consumption, pollution and the consumption of other resources. Mastering the breakthrough developments of new technologies is of capital importance for the railway industry to deliver smart and efficient solutions.Indeed, essential to the growth of the rail industry is the reduction of the overall life cycle exploitation costs of all rail sub-systems. The Traction Drive sub-system is one of the main sub-systems of a train as it moves the train converting energy from an electrical source (directly or via a chemical source) into a mechanical one. RECET4Rail will focus on the following new technologies for the Traction Drive sub-system: development of design approaches, end-to-end conception time evaluation and feasibility/performance study of 3D printing technologies for new traction’s components use cases; Dynamic Wireless Power Transfer system sizing for actual city profiles focused on opportunistic charging; improving the understanding of the robustness and reliability of high voltage SiC modules; and development of smart maintenance approaches enabled by predictive analytics, trained on big data. RECET4Rail will provide essential knowledge that will lead to future improvement of the high TRL level S2R traction demonstrations on trains done by the S2R Members, preparing also future S2R key work on domains like digitalisation applied to Traction, environmental sustainability (especially devising carbon free traction systems) or reinforcement of standardisation to lower complexity and costs

Keywords: reliability and robustness engineering,predictive maintenance,wireless charging,multidisciplinary optimisation,sic semiconductors,additive manufacturing,energy efficiency