Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Graphene NanoPlatelets current collectors based fully Printable Passivated Perovskite PhotoVoltaics (GNPs4PVs)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 191149.44
EU funding (EUR): 191149.44
Participants: 1
Project status: TERMINATED

Due to their high efficiencies (>25%), low-cost and compatibility with scalable, low energy demanding fabrication techniques, perovskite solar cells (PSCs) are the most promising PV technology to replace silicon. However, there are challenges towards their commercialisation, including the low operational stability, the use of expensive components (gold) and the need for expensive, high temperature/vacuum deposition equipment. These complexities increase the manufacturing cost/carbon footprint and reduce the manufacturing throughput. A promising way to overcome these challenges is by adopting the Carbon-based PSCs (CPSCs) configuration, in which the gold electrode is replaced by a low-cost printable carbon (graphite-based) conductive film. However, due to the electronic losses at the Carbon/Perovskite interface and the high sheet resistance of graphite-based Carbon electrodes (>10 Ohm/sq), the highest reported certified power conversion efficiency (PCE) for CPSC is just 12.8%. The research carried out under this proposal aims to: 1) generate the first CPSC with certified PCE > 20% and operational lifetime comparable to commercial technologies and 2) demonstrate stable CPSC modules (100cm2) with >15% PCE. This will be enabled by exploiting novel printable Graphene Nanoplate based electrodes (replacing graphite), perovskite passivation and interfacial engineering approaches. Such an outcome would be tremendously important for the EU market and will attract the attention of industry towards commercialization. The expected outcome will enable a significant reduction in the levelized cost of electricity to 0.03 €/kWh, even below the cost of traditional energy sources. Also, a significant reduction of CO2 emissions is expected, thanks to the excellent device lifetime potential and the low energy demanding fabrication processes. Therefore, the demonstration of CPSCs with the aforementioned capabilities would represent a significant scientific and technological breakthrough.

Keywords: photovoltaics,perovskite solar cells,graphene nanoplatelets,current colletors,fully printable solar cells,passivation,interfacial engineering,upscaling,solar panels,lcoe
Adaptive plasticity as a key for invasion success in disturbed ecosystems (INVASOMICS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2024-09-30
Duration (months): 36.0
Total project cost (EUR): 246669.12
EU funding (EUR): 246669.12
Participants: 2
Project status: SIGNED

Invasive species are a major constituent of global change, threaten local biodiversity, ecosystem services, and cause serious economic damage. Invasion science has tried to discern the factors that determine whether a non-native population will become invasive or not. Invasive populations are usually depleted in genetic diversity, creating the so-called 'invasion paradox' because traditional perspectives consider high genetic variation to be crucial for rapid adaptation to novel environments. Recent theoretical advances trying to solve this paradox propose that contemporary pre-adaptation to human-altered habitats within the native range or during the transport stage in the introduction can promote invasions. If this is true, introduced populations will exhibit increased adaptive tolerance to a stressor associated with transport, e.g. eutrophication, contributing to their success in the recipient environment. The aim of this project is to understand adaptive mechanisms that promote invasion success in widespread invasive freshwater vertebrate and invertebrate species. I will study the phenotypic differentiation of wild populations of the eastern mosquitofish in an eutrophication gradient, complemented with laboratory ecotoxicology experiments, both in the native (Florida) and invasive (Spain) ranges of the model species. This intraspecific comparison will be supported by the interspecific study of 3 sympatric freshwater amphipod species in Germany to assess potential competitive shifts in the invasive ones stemming from higher tolerances to eutrophication. Including natural populations with such particularly well described invasion histories will show why some populations become invaders and others do not. Current developments in molecular genetics , e.g. ‘-omics’, give an excellent precise tool to investigate the links between the disciplines of evolutionary biology, ecotoxicology, and invasions science and help elucidate the paradox.

Keywords: invasive species
Clathrin-mediated endocytosis in plants: mechanistic insight into the TPLATE REcycling compleX and its interplay with AP-2 (T-Rex)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Cellular, Developmental and Regenerative Biology
Panel description: Structure and function of the cell, cell-cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Belgium
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-07-01
End date: 2021-12-31
Duration (months): 66.0
Total project cost (EUR): 1998813.0
EU funding (EUR): 1998813.0
Participants: 1
Project status: CLOSED

Cells communicate with the outside world through proteins anchored in their plasma membrane and hereto constantly adjust their plasma membrane (PM) proteome. In this adjustment process, removing proteins from the PM mainly occurs through clathrin-mediated endocytosis (CME). Mechanistically however, this process remains poorly understood in plants. A recent study from my group has shown that, in contrast to other model systems, plant CME involves two early endocytic adaptor protein complexes: the evolutionary conserved Adaptor Protein 2 complex (AP-2) and the newly identified TPLATE complex (TPC). In the same study, we also show that both complexes have overlapping but also independent functions in driving CME in plants, implying that plants use additional ways to recognize membrane proteins (cargo) for internalization. In this project I will use an integrative approach to unravel the early steps of CME in plants. Specifically, I will address the following biological questions: - Is the evolutionary retention of the TPC in plants causal to specific cargo recognition? (WP1) - What are the spatio-temporal dynamics of TPC and CME effectors at the plasma membrane? (WP2) - How does acute removal of TPC subunits affect complex recruitment and CME? (WP3) - How is the TPC organized at the structural level? (WP4) - Which interactions occur and can we couple subunit/domain structures to functionality? (WP5) To answer these questions, I will combine state-of-the art proteomics with highly dynamic multi-color live cell imaging and structural biology. The overall objective is to gain a deep mechanistic insight into the developmentally essential process of CME in plants. This will enable me to specifically specifically modulate the abundance of plasma membrane proteins involved in nutrient uptake, toxin avoidance, cell wall formation and hormone and defence responses. Understanding TPC-dependent CME will also provide insight into evolutionary aspects of endocytosis.

Keywords: plant clathrin mediated endocytosis,adaptor proteins,ap 2,tplate complex
Sustainable plasmon-enhanced catalysis (SPECs)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-01-01
End date: 2024-06-30
Duration (months): 66.0
Total project cost (EUR): 1596481.0
EU funding (EUR): 1596481.0
Participants: 1
Project status: SIGNED

Industries creating inorganic, organic, and agricultural chemicals use a staggering 4.2% of the worldwide delivered energy, mainly from unsustainable fossil fuels. Meanwhile, the sun provides energy that could be utilized to power photochemical reactions sustainably and cleanly. Recent advances revealing how localized surface plasmon resonances (LSPRs), light-driven electron oscillations in metal nanoparticles, can concentrate light at the molecular scale made the dream of efficient photochemistry one step closer. However, plasmonic materials are almost exclusively constructed from the rare and unsustainable metals Ag and Au. In addition to being incompatible with current industrial practices relying on catalytic surfaces to lower energy barriers and guide reactions, Ag and Au cause prohibitive cost challenges for real-world applications. But there is hope: several of the few metals predicted to sustain LSPRs and become potential alternatives to Ag and Au are amongst the most abundant, i.e. sustainable, elements on Earth (Al, Mg, Na, K). The way forward, and key objective of my proposal, is thus to design, synthesize, and understand multimetallic nanostructures where a cheap, Earth-abundant plasmonic material traps and concentrates (sun)light directly at a catalytic surface to efficiently and intelligently power and choreograph chemical reactions. To achieve this ambitious goal, I devised a project concurrently advancing important aspects of sustainable plasmon-enhanced catalysis, from the development of two synthetic approaches for Earth-abundant plasmonic-catalysts, to the fundamental studies of light-trapping in these new materials with state-of-the-art numerical and experimental approaches and the unravelling of the relative contribution of plasmon-generated hot electrons, enhanced field, and heat using key model chemical reactions. These results will help develop a more sustainable future by lowering our reliance on both fossil fuels and rare metals.
Biocatalytic upgrading of natural biopolymers for reassembly as multipurpose materials (BioUPGRADE)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Spain,Spain,Sweden,Finland
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2020)
Start date: 2021-05-01
End date: 2025-04-30
Duration (months): 48.0
Total project cost (EUR): 2992140.0
EU funding (EUR): 2992140.0
Participants: 5
Project status: SIGNED

The BioUPGRADE action unites functional genomics and material science advances, to galvanize the sustainable transformation of nature’s major structural polymers into a cascade of high volume and specialized bioproducts. Technology ready results (TRL 4-6) are anticipated, serving as an innovation launchpad that tackles climate change while revolutionizing the materials used in our daily lives. The action is differentiated by its: 1) emphasis on upgrading nature’s main biopolymers for use in performance advantaged products with emergent properties; 2) pursuit of cell-free, biocatalytic technologies that leverage the design principles and finesse encoded in surface-acting enzymes and non-catalytic proteins, which will permit fine-tuning of natural polymer structures for customized applications that can not be achieved through dominating thermochemical approaches; and 3) creation of novel, fully bio-based materials based on controlled assembly of tailored biopolymer components, guided by new capacity to probe biopolymers and resulting materials from nano to macro scales. BioUPGRADE will apply advances in computational biology to mine untapped information in escalating genomic and proteomic datasets; introduce a bio-customize framework that stretches well beyond current synthetic biology concepts; and establish a structure-function matrix for tailored biopolymers and new assemblies. Key project deliverables include: 1) application-driven functional screens critical to breakthroughs in bio-technologies for materials engineering, 2) an innovational, biocatalyst toolbox of surface-acting proteins designed for bio-based materials engineering, and 3) protocols for controlled assembly of tailored biopolymers into fully bio-based materials, from sustainable textiles to personal health products. BioUPGRADE is positioned for success because it mobilizes proven scientific and commercial expertise in establishing lasting bio-economies that reduce reliance on fossil resources.

Keywords: functional genomics,carbohydrate active enzymes,protein design and engineering,polysaccharides,biomass,lignocellulose,bio based materials,bioeconomy
An Open Innovation Test Bed for Nano-Enabled Bio-Based PUR Foams and Composites (BIOMAT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Innovation actions
Countries involved: Spain,Germany,Spain,Spain,Italy,Israel,Germany,Spain,Italy,Italy,Germany,Spain,Italy,Latvia,France,Portugal,Portugal,United Kingdom,Portugal
Call: Open Innovation Test Beds for nano-enabled bio-based materials (IA) (H2020-NMBP-TO-IND-2020-twostage, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 16673033.34
EU funding (EUR): 14564022.89
Participants: 28
Project status: SIGNED

Polyurethane (PUR) products, which include foams for building, construction, automotive and furniture and bedding, are petroleum-based and usually lack important properties. The need for sustainability in these industries leads to the development of cost-efficient processes and sustainable added-value products from low carbon footprint materials. The main objective of BIOMAT is to establish an Open Innovation Test Bed (TB) for the benefit of industries and SMEs, aiming to facilitate the cross-border partnership and accelerate innovation in nano-enabled bio-based insulation materials for these industries. Through the creation of a Single-Entry Point (SEP), SMEs and other industrial parties will have open access at a competitive price to physical facilities (pilot production lines) and services (characterisation, nanosafety, standardisation/regulation, business/marketing plans as well as technological and business-oriented mentoring) which will be focused on manufacturing and testing of nanoparticle-enabled functional PUR-based foams for the above mentioned industrial sectors. The SEP will follow all EC guidelines related to the establishment of new entities providing services through different testbeds across Europe. BIOMAT ecosystem will cover the entire Value Chain (VC) from fundamental biomaterials and functional nanoparticles to the final products and their proof of concept in an industrial environment, thus accelerating the market uptake of the new nano-enabled sustainable bio-based products. BIOMAT will, therefore, fill the existing gaps in the VC of these industrial sectors, by providing new services and support at different levels the use of such materials in these key industries.

Keywords: bio materials nanoparticles,nano enabled materials,inline monitoring,nanosafey,standardization,pilot lines
Contactless, non-invasive scanner to detect, visualise, capture, and digitally preserve fingerprints and trace evidence in forensic investigations in one rapid, quality-proof step (SCANOVIS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-07-01
End date: 2019-09-30
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Time is crucial in criminal investigations! A fast identification of suspects increases the chance of solving a case and helps preventing further crimes. Fingerprints provide extremely strong physical evidence to the investigation authorities and help to identify suspects. Pieces of evidences are usually transported to forensic laboratories, dusted with a brush or prepared with aggressive and toxic chemicals, to make traces visible and capture them by photography. This takes up to 36 hours, because several time-consuming steps are necessary. Furthermore, the traces can be destroyed in the process and no further examination is possible. Besides being a substantial part in a criminal investigation, fingerprint forensics lacks new and modern methods to increase speed, quality and applicability. SCANOVIS develops disruptive, patented laboratory and handheld scanners to capture prints. Instead of chemicals, a laser is used to precisely detect traces and digitally visualise 3D data in a rapid quality-proof step, without compromising evidence. Traces are visualised non-invasively, contactless and non-contaminatively, without using any toxic chemicals. Prints can be captured in less than 60s at the crime site and distributed digitally very fast. As fighting crimes will always be an important topic and many authorities plan to modernise their equipment, the forensic tools market is predicted to show a stable, long-term growth. Initially a lab scanner is introduced into the market, in a second step a mobile scanner greatly reduces the investigation time and detects traces that go unnoticed now. It broadens the market as each police officer can use the mobile scanner. SCANOVIS anticipates a turnover of 26M€ and an additional staff of 46 employees in 2024. SCANOVIS vision is to revolutionise forensics and become the global standard tool to make the fight against crime and terrorism more efficient, more successful and hence protect freedom and security of Europe and its citizen.

Keywords: dactyloscopy,fingerprint scanner,forensics,latent fingerprint,criminal investigation,laser spectroscopy
A resource-efficient granulation process for advanced formulation of any compound in food and pharma production (AGS)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: Italy,Italy,Finland
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-1-2015, 2015)
Start date: 2015-12-01
End date: 2016-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 3
Project status: CLOSED

Polibiotech, an SME from Italy, has developed a patented advanced manufacturing process that successfully formulates any chemical compound quicker, at a lower cost and resource-efficiently. Current chemicals production procedures of wet and dry granulation have difficulties with universality, waste ingredients and energy consumption. Nutraceutical formulation requires repetitive research and testing to prove viability and is an extremely inefficient, time-consuming process (lasting up to several months). The Aerodynamic Granulation System (AGS) is a new process of dry granulation that revolutionises the formulation process and successfully manufactures any drug. The system uses a gas flow to optimise particle transportation and granule separation. The system is eco-sustainable as less raw materials are input and waste can be recycled through the use of a continuous process in a closed system. The AGS method reduces formulation time from several months to one day. At peak performance the AGS could produce more than one new formulation per week and a basic machine would have capacity to produce 1 tonne a day. The system concept will initially be applied to the nutraceutical markets; however, any product that requires the combination of chemicals to form a homogeneous compound can utilize this technique including the pharmaceutical market. An advanced prototype AGS has been constructed and trialled in an operational environment and a variety of products have been formulated. Within the overall project Polibiotech intend to: construct a second pilot plant in Italy; engineer a series of online quality control tests; validate the full scale AGS line for the production of nutraceutical compounds and gain certification for manufacturing roll out within the EU.

Keywords: aerodynamic granulation,continuous system,closed system,gas flow,efficiency,cost saving,compound formulation,nutraceuticals,food production,drug production,eco friendly
High-order two-phase flow modelling (HO2PF)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-02-01
End date: 2025-01-31
Duration (months): 36.0
Total project cost (EUR): 246669.12
EU funding (EUR): 246669.12
Participants: 2
Project status: SIGNED

Flows of two immiscible fluids separated by an interface, referred to as "two-phase flows", are ubiquitous in nature and central to many engineering applications. They contribute to the underlying principles and processes of a vast range of key sectors such as energy, transportation, manufacturing, and healthcare, and are relevant to the study of climate-change and disease-spreading. Most important to Europe's current challenges, the study of two-phase flows is instrumental in achieving the "European Green Deal" objective of reaching carbon-neutrality by 2050. Yet, despite their clear significance, our understanding of two-phase flows remains limited. Recently, computer simulations have become viable alternatives to experiments for their study, but they are still limited in terms of their flexibility, efficiency, and accuracy. The research programme proposed for this fellowship will provide a paradigm shift in the way two-phase flows can be simulated and therefore studied, with the development of the first high-order numerical framework for the accurate solution of their evolution in complex three-dimensional flow domains. This will entail increasing the order of representation of the local numerical approximations of the interface between the two phases, from linear to quadratic. This enhancement will in turn allow the development of high-order numerical schemes for the transport of this interface, and the estimation of the surface-tension force acting on it. These highly accurate schemes will be released to the research community in an open-source library. Not only will this enable the design of the next generation of low-emission energy-conversion technologies, which are crucially needed to reach Europe's environmental targets, but this will also yield substantial advances in manufacturing and health-related applications and in the prediction of climate-change, and will help devising future environmental and public health policies.

Keywords: two phase flow modelling,volume of fluid method,interface reconstruction,high order