Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Twinning on Functional Layered Materials for Advanced Applications (FUNLAYERS)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Portugal,Spain,Germany
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 1499885.0
EU funding (EUR): 1499885.0
Participants: 3
Project status: SIGNED

Radical technological transformation in the last one hundred years have been based on the understanding electronic properties of materials that has enabled their application in electronics, energy harvesting, among others. There is no doubt that the solution to the new challenges of our time will also come from the understanding of materials and their applications. In this context, layered materials are very promising on account of their broad range of electronic properties, including insulators, semiconductors, conductors, superconductors, ferromagnets and antiferromagnets, that can lead to a variety of applications. FUNLAYERS will focus on two types of applications, energy storage and spintronics. The exploration of layered materials is such a vast enterprise that requires the engagement of an army of different institutions. There is a huge effort, worldwide, and if Europe wants to remain competitive and be a major player in this incoming revolution, it is essential to strengthen the capabilities of institutions everywhere, most notably in widening countries. FUNLAYERS will bring together three partners to march together in this direction, two consolidated research institutions with outstanding scientific reputation, MPG and ALBA-CELLS, and INL, in Portugal. Taking advantage of incipient collaborations in layered materials, this twinning exercise will put INL to speed in this blooming research field and will benefit all partners thanks to their complementary strengths. FUNLAYERS will identify weak points in INL research capacity, and provide training, knowledge sharing, exchange of good practices and access to facilities to address these points. It will engage the three partners in collaborative research aiming at high impact results, and lay the foundations to sustain this collaboration and the positive impact of the project over time and bring concrete solutions to our greatest challenges, namely, climate change and low energy consumption.

Keywords: layered material,2d materials,energy storage,spintronics
Light Dark Matter: New Directions for Theory and Detection (Light-Dark)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Israel
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-05-01
End date: 2027-04-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SUSPENDED

Dark matter is one of the biggest mysteries of the universe, yet its particle identity is unknown. This proposal focuses on light dark matter (LDM), with mass below a GeV. In Light-Dark, I will pursue two intrinsically complementary directions: (I) I will explore novel theoretical frameworks for LDM; and (II) I will develop new theoretical concepts to directly detect it in the laboratory. This pioneering theory work will lay the foundation for future experimental realizations and is crucial in the quest to unearth the identity of dark matter. I will carry out a comprehensive research program designed to tackle these challenges, and I believe that I am uniquely positioned to do so. Regarding (I), the wealth of annihilation channels, scattering processes, self-interactions, decay modes and mass splittings opens up a host of possible frameworks to set the LDM abundance, which I will explore. I have already proposed a paradigm-shifting idea in the form of the Strongly Interacting Massive Particle (SIMP) mechanism, which, along with other new ideas for LDM, will be thoroughly studied. Regarding (II), the study of novel target materials for LDM, sensitive sensors, collective excitations, detection philosophies and the interplay between them is crucially still in its infancy. I will explore new theoretical concepts and synergies in these experimental aspects, including the use of superconducting nanowires, microwave kinetic inductance devices, 2D layered materials, ferroelectrics and directionality, with prospects to detect LDM orders of magnitude beyond current abilities, down to the meV scale. Proof-of-principle has already been established for nanowires, where, using data from a tiny prototype device, I have already broken new ground in LDM parameter space. The innovative theoretical approaches presented here open up an exciting and groundbreaking ?eld of research. The proposed investigations are both timely and essential, paving the way towards a dark matter discovery.

Keywords: light dark matter,light dark matter theory,simp dark matter,direct detection of sub gev dark matter,low threshold direct detection
Multifaceted molecular MRI toolbox to uncover Zn2+ in physiology and pathology (ZincMRI)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Israel
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-04-01
End date: 2028-03-31
Duration (months): 60.0
Total project cost (EUR): 1999549.0
EU funding (EUR): 1999549.0
Participants: 1
Project status: SIGNED

To reveal the multiple aspects (molecular, cellular and anatomical) of a studied biological process (in health or disease), it is necessary to have the ability to spatially map the multiplexity and dynamicity of intra- and inter-cellular events in the context of a whole organism. We here propose a conceptually novel approach to spatially map the multicomponent information of a studied biological phenomenon, from the deep tissue of a studied subject using a single imaging setup. In realizing the importance and diverse roles of labile Zn2+ in specific tissues, we aim to develop ZincMRI. ZincMRI is a molecular imaging toolbox designed to provide orthogonal MRI readouts, with which we aim to monitor the multiple facets of Zn2+ biology through: (i) quantitatively mapping dynamic changes in intra- and extra-cellular levels of Zn2+; (ii) spatially monitoring Zn2+-induced gene expression, and (iii) providing complementary high-resolution anatomical views of the studied subject. To establish ZincMRI, we will design, develop, and implement: (i) fluorinated synthetic compounds as MRI responsive agents for quantitatively mapping changes in labile Zn2+ levels using 19F-MRI (Aim 1); and (ii) conditional MRI reporter genes for mapping Zn2+-induced transcription with 1H-CEST MRI (Aim 2). Capitalizing on the orthogonality of the signals obtained with 19F-MRI and 1H-CEST MRI, ZincMRI will be applied to map, in vivo, from the hippocampus region of the brain, both the dynamic changes in Zn2+ levels and the transcription of Zn2+ regulatory elements in response to physiological and pathological stimuli (Aim 3). We envision that ZincMRI, which unconventionally aims to study two aspects of Zn2+ biology using a single imaging modality, and is also applicable for the study of deep tissues, may affect not only the way we study this ion, but could also be further extended to study other metal ions with biological relevance by capitalizing on the scientific paradigm proposed here.

Keywords: mri reporter genes,mri responsive agents,19f mri,molecular and cellular mri,zinc mri
NEUTRINAI: eNErgy-frUgal internet of Things Networking with generative AI modules (NEUTRINAI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 1
Project status: SIGNED

This project aims to design energy-efficient communication technology and protocol for the 6th generation (6G) Internet of Things (IoT) communication system, in which energy efficiency is one of the essential Key Performance Indicators (KPIs) to realize sustainable IoT networking. The energy-efficient protocol designs for IoT devices serving 6G applications are more challenging than conventional wireless sensor networks, as we need to consider the energy cost caused by the introduction of the Artificial Intelligence (AI)/ Machine learning (ML) model as well as that of the primary radio circuit. However, most related works do not consider the energy cost of introducing the ML model, which affects the overall energy efficiency of the communication protocols. In order to realize the reduction of the overall energy consumption of AI-empowered IoT devices, this project newly introduces generative AI modules and wake-up radio technology into IoT devices operating with batteries, by which IoT devices can suppress unnecessary data transmission, and communication is taken place in an energy-efficient manner by cooperatively transmitting signaling, informative data, and ML model from devices to devices. This project will design a new communication framework integrating generative AI modules, investigate the system-level performance of G-AI-based communication systems, and clarify the gain brought by the introduction of G-AI modules in terms of energy efficiency and accuracy.

Keywords: energy efficiency,generative ai,machine learning,wake up radio,internet of things
Quantum information science and Ultrafast nonlinear coherent control at the ATTOsecond timescale (QU-ATTO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany,Sweden,Spain,France,Greece,Portugal,Italy,Belgium,Lithuania,Hungary
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2024-09-01
End date: 2028-08-31
Duration (months): 48.0
Total project cost (EUR): 4178723.66
EU funding (EUR): 3953253.6
Participants: 23
Project status: SIGNED

Understanding the interaction between electromagnetic radiation and matter is crucial for unravelling the internal structure and processes of materials. Electromagnetic waves exhibit both wave-like and particle-like behaviour, with the quantized nature of light becoming apparent in the realm of quantum technologies. The QU-ATTO network aims to merge the fields of quantum optics and quantum information science with attosecond physics. This involves focusing on experimental campaigns to highlight quantum aspects in the interaction of intense laser fields with matter and advancing theoretical descriptions for a comprehensive understanding of the quantum state of light associated with intense laser fields. Traditionally, attosecond pulses have been generated using table-top femtosecond lasers. However, recent experiments performed at free-electron lasers (FELs) have demonstrated the production of isolated attosecond pulses and precise control of attosecond waveforms for pulse trains, leading to remarkable advancements in attosecond science. The network also aims to leverage recent advances in seeded FELs and high-intensity high-harmonic generation (HHG)-based attosecond sources to demonstrate the coherent control of electronic dynamics in systems of increasing complexity. The QU-ATTO network represents a comprehensive effort to advance the understanding and control of the interaction between electromagnetic radiation and matter, with a specific focus on merging quantum optics, quantum information science, attosecond physics, and free-electron laser science. The doctoral candidates (DCs) in the network will receive multifaceted scientific training encompassing experimental and theoretical aspects of quantum information science, strong-field physics, and soft X-ray and X-ray science, as well as extensive training in transferable skills and self-management techniques.

Keywords: attosecond physics quantum optics coherent control ultrafast electronic dynamics
Non-Equilibrium Diffusion in Complex Environments (NoDiCE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Condensed Matter Physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: France
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Diffusion is at the root of a huge number of microscopic structural and transport processes. During the last century, Einstein and Boltzmann's theories were successful in describing equilibrated systems, but they are not applicable to numerous strongly non-equilibrium conditions in nano-technological and macromolecular-scale biological contexts. Notably, many systems involve energy injection at an interface, either under dissipative shear flows or chemical reactivity. These common non-equilibrium situations are difficult to observe with precision and describe with statistical theory. NoDiCE’s purpose is thus to design model experiments placing functional colloidal particles in complex, non-equilibrium environments with quantitative assessment based on delicate and simultaneous observations of the particles’ advective and diffusive motions, along with their precise spatial organization. Our observations exploit evanescent- wave microscopy to observe fluorescent nanoparticles driven out-of-equilibrium in microfluidic devices, providing 3D nanometric precision at kHz temporal scales. Fluorescence correlation and atomic force spectroscopies complement these measurements, providing DC to MHz bandwidth and similar spatial precision. We will demonstrate how non-trivial interactions of hydrodynamic origin with a boundary reveal novel nanoscale self-organization strategies, and learn how to integrate a hydrodynamic component into the statistical theory. We then enter the recent scientific debate about the extent to which Brownian motion can be impacted by reactive environments with catalysis. Lastly, we combine these elements with particles that present specific surface binding and are driven out of equilibrium by an external flow. The insights provided by our model experiments open a path for the developments of breakthrough self-assembly strategies, reaction- pathway analysis based on particle dynamics, and possible next-generation diagnostic tools.

Keywords: micro and nanofluidics,dynamic surface interaction,intermolecular forces,colloidal dynamics
Implementing value-based oncology care at European cancer hospitals: An AI-based framework for assessing real-life effectiveness of novel cancer therapies in real-time (ONCOVALUE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Unlocking the full potential of new tools, technologies and digital solutions for a healthy society
Action type: Research and Innovation actions
Countries involved: Finland,Netherlands,Denmark,Portugal,Italy,Germany
Call: New methods for the effective use of real-world data and/or synthetic data in regulatory decision-making and/or in health technology assessment (HORIZON-HLTH-2022-TOOL-11, 2022)
Start date: 2022-12-01
End date: 2026-11-30
Duration (months): 48.0
Total project cost (EUR): 6953003.51
EU funding (EUR): 6953003.5
Participants: 13
Project status: SIGNED

ONCOVALUE will unlock the full potential of real world data (RWD) collected in European cancer hospitals and institutes to ease the decision-making of regulators on cost-effectiveness of novel cancer therapies. To achieve this, we build up data collection and processing capabilities of leading European cancer hospitals to create a high-quality clinical, quality of life, and adverse events data-sources. With the use powerful AI technologies, we will transform unstructured data originating from medical notes and medical images into structured data to enable analytics and real world evidence (RWE). This RWE will be directly available for clinicians for treatment management and for health regulatory and HTA bodies to adopt optimized data-driven methodologies for the effective assessment of medicinal products and digital health innovations. For that, we will provide an end-to-end infrastructure for RWD reporting in health regulatory and HTA decision-making and address the legal constraints in the cancer hospitals to ensure secure and legal access to RWD. Furthermore, ONCOVALUE will ensure the implementation of the developed guidelines and methodologies, by providing trainings for the collection and management of high-quality RWD in European cancer centres and for the analysis of this data by HTA and regulatory bodies. By opening the door to widespread regulatory and HTA integration of RWD, ONCOVALUE will lead to safer, more efficient, and affordable therapies, technologies, and digital solutions for (personalised) cancer care. As such, ONCOVALUE is positioned to contribute to increased cost-effectiveness and subsequent sustainability of cancer care. Systematic collection and evaluation of the patient reported outcomes will lead to improved well-being of the patients. Subsequently, on the long-term implementation of value-based cancer care at European cancer hospitals will aid in reducing the growing burden of cancer treatment in the EU and worldwide.

Keywords: real world data real world evidence healthcare oncology cancer hta decision making regulatory decision making cost effectiveness
Reinventing High-performance pOwer converters for heavy-Duty electric trAnSport (RHODaS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Clean and competitive solutions for all transport modes
Action type: Research and Innovation actions
Partnership: 2ZERO (co-programmed)
Countries involved: Spain,Austria,Denmark,Poland,France,Germany
Call: Nextgen EV components: Integration of advanced power electronics and associated controls (2ZERO) (HORIZON-CL5-2021-D5-01, 2021)
Start date: 2022-05-01
End date: 2026-01-31
Duration (months): 45.0
Total project cost (EUR): 5956938.0
EU funding (EUR): 5956936.0
Participants: 9
Project status: SIGNED

RHODaS project aims at developing disruptive topologies of power converters using new semiconductor materials as well as cutting-edge digital technologies to improve architecture efficiency, power density, reliability, cost and sustainability. Moreover, multi-disciplinary approaches of modular power electronics for Integrated Motor Drive (IMD) and ecodesign considerations are addressed, to create compact solutions that can be integrated in a wide range and heavy-duty vehicles, enabling these electric vehicles to be more sustainable and autonomous throughout the entire lifecycle of their components. Nevertheless, power electronics solutions that use Wide Band Gap (WBG) devices can also be applied to light-duty vehicle types M and L, with competitive advantages on the efficiency and power densities compared with current technologies. Finally, the RHODaS project targets the validation of the proposed solutions in electric drivetrains of 1200V for zero emissions class N3 (carriage of goods > 12 tonnes) and O4 (trailers >10 Tonnes), which correspond to USA Class 7-8 heavy duty vehicles (>12 Tonnes) and beyond.

Keywords: electric vehicle,power converter,heavy duty vehicle
Next-Generation Radiation Detectors in Experiments with Spin-Oriented Exotic Nuclei (RADESO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain,United States
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-01
End date: 2028-06-30
Duration (months): 36.0
Total project cost (EUR): 420966.72
EU funding (EUR): 420966.72
Participants: 2
Project status: SIGNED

Exciting new opportunities for experiments with beta-decaying atomic nuclei have arisen recently at CERN ISOLDE with the new spectroscopy station called DeVITO. The novelty of the setup stems from its integration with the laser-polarisation beamline that induces spin orientation in radioactive ions or atoms. This unique combination enables spectroscopy measurements with spin-oriented nuclei that emit radiation anisotropically. The ability to exploit the directional distribution of radiation represents a significant advance over conventional beta-decay experiments, which, while benefiting from the high angular-momentum selectivity of the decay process, constantly struggle to infer nuclear spins and parities unambiguously. These crucial quantum numbers, essential for discussing complex phenomena observed in nuclei, can be inferred from experimental beta-decay asymmetries measured in coincidence with delayed radiation (gamma rays and/or neutrons) emitted from polarised nuclei. The RADESO project aims to acquire knowledge about the hitherto unknown or tentative quantum properties of the nuclear levels and radiation emitted from very neutron-rich nuclei. One of the objectives is to incorporate next-generation spectrometers into the DeVITO to enhance the detection sensitivity for neutrons and gamma rays emitted from laser-polarised beams. The RADESO project is targeted at experimental studies of very neutron-rich nuclei to provide robust experimental observables capable of benchmarking beta-decay calculations on a more fundamental level. The main goal is to gain insight into the mechanism of beta-delayed neutron emission, which is the primary decay mode of exotic nuclei involved in one of the astrophysical processes responsible for the formation of about half of the chemical elements heavier than iron.

Keywords: neutron rich nuclei,beta decay,beta delayed neutron emission,laser polarisation,spin orientation,neutron detectors,gamma ray detectors