Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Health.E Lighthouse Support Initiative (HELoS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Public-private partnerships
Destination: Electronic Components and Systems
Action type: Coordination and support actions
Partnership: ECSEL (Art-187)
Countries involved: Germany,Germany,Germany,Belgium,France,France,Netherlands,Netherlands
Call: ECSEL-2019-3-CSA-HealthE (H2020-ECSEL-2019-3-CSA-Health-E-one-stage, 2019)
Start date: 2019-07-01
End date: 2022-04-30
Duration (months): 34.0
Total project cost (EUR): 499478.75
EU funding (EUR): 499478.75
Participants: 9
Project status: CLOSED

The objective of the HELoS CSA is to support the Health.E Lighthouse Initiative Advisory Service (LIASE) in its ambition to accelerate innovation in medical devices (“Moore for Medical”). Health.E will accelerate the innovation in medical devices and systems by stimulating the development of open technology platforms and standards , thereby moving away from the inflexible and costly point solutions that presently dominate electronic medical device manufacturing. Open technology platforms, supported by roadmaps, will generate the production volumes needed for sustained technology development, resulting in new and better solutions in the healthcare domain. Health.E will: • Translate the needs of medtech and pharma into ECS opportunities; • Build on the ECS Strategic Research Agenda and identify the gaps; • Stimulate initiatives: towards open technology platforms and standards for medical devices; to anticipate the requirements for regulatory, Notified Bodies, clinical trials and market access; to better apply to the current care practices, necessary conditions for market access. • Connect to European initiatives and relevant communities including PPPs such as ECSEL, IMI, Eureka, and relevant industry associations In the HELoS CSA, three main components are identified that need to be connected in order to address the complex issue of innovation in the medical industry: • Connecting existing networks: ECSEL projects, (inter)national and regional projects and initiatives; • Addressing and connecting scientific/technical issues and non-technical aspects e.g. legal, regulatory, standardization, ethical, economic (cross-cutting issues); • Extending the network of stakeholders and markets across Europe (spreading excellence, facilitating international collaboration, new applications); • The dissemination of the results of this initiative to the stakeholders and the general public.

Keywords: moore for medical,electronic components and systems for healthcare,open platforms,smart catheters,implantables,personalized medicine,organ on chip
Production Method for Ironless Electric Motors (PROMINEL)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Norway
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-10-01
End date: 2022-06-30
Duration (months): 33.0
Total project cost (EUR): 3149950.0
EU funding (EUR): 2204965.0
Participants: 1
Project status: CLOSED

Ironless electric motors are lighter than legacy iron-cored electric motors given the same power output, but typically costs much more. Alva's patent-pending Fibre Printing production technology promises a reduction in production cost of ironless motors, and an increase in motor performance, finally solving the production bottleneck that has kept ironless motor and generator technology from reaching their potential in many markets as a technically superior choice over conventional motor types. The main objective of the PROMINEL project is to produce a prototype demonstrator production line for electric motors based on Alva's novel Fibre Printing technology. Alva will use the new production line for fast up-scaling of the company's proprietary motor designs, acting on a unique market opportunity in the commercial UAV market by offering a lighter and more energy efficient electric motor product for aerospace propulsion systems. After successful market penetration in the commercial UAV sector, the Fibre Printing technology has potential to also impact other industries where ironless technology is higly beneficial, including wind power generators, medical devices, robotics, precision manufacturing equipment and automotive and marine propulsion systems.

Keywords: electric motor manufacturing,materials science,advanced composites,lightweight engineering,automation
Waterjade: the global platform to predict water resources (Waterjade)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Water is called the new gold of the 21st century, yet, due to climate change, water resources are becoming ever more discontinuous, creating hazardous sitations and big uncertainties in numerous sectors, like energy, where water is the primary ingredient for daily operations. One of the most recurrent question raised by professionals is: "how much water is there and when will it become available"? We have developed a new technology, called Waterjade, capable of predicting water resources at high resolution, both in terms of snow and river discharge. Differently from other competitive technologies, it adopts a physically based modeling approach that integrates multiple sources of data, like in-situ stations, numerical weather predictions and satellite data. The advantages are increased accuracy and scalability to ungauged basins. Our customers are hydropower companies, whom we deliver a service of snow monitoring upstream the production plants, so they can quantify the energy that is likely to be produced in the long run, and a service of short-term inflow predictions to the plants, useful for safety reason and to optimize the energy production. We are extending the service of snow monitoring also to the public sector, that use it for safety reasons (avalanches) and as an index to anticipate drought. Working with public and private sectors is giving positive feedback, both in terms of credibility and accuracy as we can benefit from the capillary distribution of in-situ stations from public agencies. The business model is a "subscription-based Service" to the Waterjade portal and the market potential is estimated in about 500 M€/y worldwide, with great potential in particular for hydropower, Europe's and world’s largest renewable energy resource.

Keywords: snow and water resources,weather predictions,water discharge,water cycle
Chinese Intelligent Language Learning (CHILL) – Using Grammar Engineering Models for Automated Error Detection (CHILL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Czechia
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-11-01
End date: 2023-10-31
Duration (months): 24.0
Total project cost (EUR): 144980.64
EU funding (EUR): 144980.64
Participants: 1
Project status: CLOSED

This Action will produce a high-precision error detection computational system for Mandarin Chinese, which diagnoses the linguistic source of grammatical errors, and uses this information to provide corrective feedback to learners. The Action takes advantage of the Applicant’s expertise in computational linguistics & their educational applications and relies on supervisor’s expertise in Chinese syntax. The Action includes an in-depth syntactical analysis and computational implementation of both the structure of Mandarin Noun Phrases and related common errors. The focus will lie on quantification, reference/deixis, cognitive status and modification. The Action will make use of well-grounded data-driven interdisciplinary methodologies, integrating standard methodologies for formal linguistic analysis and methodologies for software development from the field of Computer Science. The supervisor and the Applicant have published together and collaborated successfully in other projects. The beneficiary, the Department of Asian Studies at Palacký University, has an excellent reputation in the field of Asian languages with a strong emphasis on new methods in language teaching. These conditions offer an optimal opportunity to develop and test the results of the proposed Action. Through the interaction with the supervisor and training-through-research, the Applicant will acquire expertise in Chinese Syntax. In addition, the beneficiary also offers state-of-the-art physical and technological infrastructure, including a Trainee Center with excellent opportunities to develop transferable skills. The training received through this Action will create valuable opportunities for the future career prospects of the Applicant, and help him fulfil his plan to establish an academic career in Europe.
Controlling Cell Fate through Smart Nanoheaters (CONFINES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-09
End date: 2018-09-09
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Achieving the control of cellular processes is one of the most intriguing challenges in cell biology and medicine. Forefront approaches based on bioengineered nanoparticles might have the potential to target specific cell pathways, thus controlling downstream cell activities in a space and time selective fashion. The present project aims to develop and to validate a smart nanovectorable to activate a specific cell signalling and, on demand, to induce heat mediated cell death of nanovector targeted cells. As proof of concept, CONFINES is conceived to target the Wnt canonical pathway, one of the most studied and fascinating cell signalling, which orchestrates central mechanisms that govern cell proliferation, polarity and stem cell fate. To achieve the proposed objectives, a controlled synthetic approach will tailor Wnt ligands on magnetic nanoparticles, combining targeting and magnetic properties in a uniquenanovector. Owing to its chemico-physical features, NanoWnt will enable complete control of the cell signalling, and it will operate in vitro (human cell cultures) and in vivo (the aquatic invertebrateHydra vulgaris), in a dual mode: i) as an activator of the canonical Wnt pathway in those contexts where it is inactive ii) or upon exposure to a magnetic field, as a nanoheater, enabling specific cell ablation by hyperthermia. From a technological point of view, the project will advance basic knowledge on thermal ablation (via magnetic hyperthermia) and holds promises for translational medicine, providing a breakthrough tool to shape cell fate of nanovector receiving cells. Furthermore, combining diverse expertise, CONFINES will offer the applicant advanced and multidisciplinarytraining in the field of nanomaterial synthesis, characterization and functionalisation as well as in hyperthermia technology, which will complement his current skills based on nanobiotechnology and cellular/molecular biology.

Keywords: nanovector,bioengineered nanoparticles,targeted hyperthermia,cell signalling,hydra vulgaris
Effects of Medication Use in Pregnancy on Infant Neurodevelopment (DrugsInPregnancy)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Norway
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-09-01
End date: 2021-08-31
Duration (months): 72.0
Total project cost (EUR): 1499439.0
EU funding (EUR): 1499439.0
Participants: 1
Project status: CLOSED

Currently, thousands of pregnant women in the EU and worldwide are being increasingly prescribed medications for which we do not have sufficient information on fetal safety. I hypothesize that our current understanding of safety pharmacology is oversimplified and that medication prescribed during pregnancy may play an unrecognized role in the development of neurodevelopmental disorders. In this research proposal we have the unique opportunity to use a large population-based birth cohort including over 100 000 mother-child pairs and biological data to study how medications may act on the offspring. This offers novel and innovative pharmaceutical insight into the safety of medications. By linking several nationwide registries (National Prescription Data Base, Norwegian Patient Registry, Medical Birth Registry) to a population-based birth cohort (n=108 000) we specifically aim to 1) estimate the effect of prenatal exposure to psychotropics and analgesics on neurodevelopment in young children using a range of methodological approaches to strengthen causal inference. With these data made available, we will 2) determine whether fetal exposure to specific medications results in epigenetic events (i.e. changes in DNA methylation) in the child, and 3) determine whether such changes increase the risks of neurodevelopmental disorders in childhood. The recent availability of large scale human data, possibility of register linkages and genome-wide mapping of DNA methylation at affordable costs makes this research proposal now possible. The size and richness of data including over hundred thousand pregnancies and existence of biological material makes this project unique. The final outcome will be fundamentally new knowledge about how medications affect the developing unborn child and will open up new horizons and opportunities for future research in a new field of “pharmaco-epigenetics” and enhance our understanding of origins of neurodevelopmental disorders.

Keywords: pharmaco epidemiology,medication use in pregnancy,psychotropics,analgesics,neurodevelopment
Enhancing Synergies for disaster PRevention in the EurOpean Union (ESPREssO)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: Coordination and support actions
Countries involved: Germany,Germany,Italy,Switzerland,France,Denmark,United Kingdom
Call: Disaster Resilience & Climate Change topic 2: Natural Hazards: Towards risk reduction science and innovation plans at national and European level (H2020-DRS-2015, 2015)
Start date: 2016-05-01
End date: 2018-10-31
Duration (months): 30.0
Total project cost (EUR): 2374367.5
EU funding (EUR): 2068021.25
Participants: 7
Project status: CLOSED

ESPREssO aims at contributing to a new strategic vision to approach natural risk reduction and climate change adaptation, thereby opening new frontiers for research and policy making. From this perspective it wants also to be of support to the EC research and development and to the JRC Knowledge Centre on Disaster Risk Management. To achieve this goal, the project structure is built upon the central role of three main challenges to be addressed in order to propose ways to mitigate differences, to identify gaps, and to overcome the boundaries among different topics: 1 To propose ways to create more coherent national and European approaches on Disaster Risk Reduction, Climate Change Adaptation and resilience strengthening; 2.To enhance risk management capabilities by bridging the gap between science and legal/policy issues at local and national levels in six European countries; 3.To address the issue of efficient management of trans-boundary crises. Activities on the three ESPREssO challenges will be performed in all work-packages. The first 3 WPs are essentially dedicated to collection of information: on relevant stakeholders’ needs, perspectives and priorities (WP1), on the existing knowledge of legal, policy and science approach at the EU level and across identified countries (WP2), and development of hazard-specific scenarios as a basis for a Risk Management Simulation tool to elicit stakeholders (WP3). The other two WPs are dedicated to the analysis of information and the preparation of proposals: analysis of information and evaluation of the proposed strategies (WP4), and preparation and dissemination of guidelines (WP5). A comprehensive approach to the ESPREssO challenges requires a strong, multi-disciplinary group. The ESPREssO team is consequently formed by partners having a well-known expertise in legal and governance issues and natural risk management, socio-economic aspects and resilience, hard science, statistical approaches to multi-risk and resilience.

Keywords: strategic vision,disaster risk reduction,challenge,resilience,adaptation,trans boundary crises
Historic response of a wide-ranging carnivore to climate change (SURVIVOR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2020-06-30
Duration (months): 24.0
Total project cost (EUR): 173857.2
EU funding (EUR): 173857.2
Participants: 1
Project status: CLOSED

This proposed project investigates novel ways of predicting the effects of future climate change on the survival of animal species. We will focus on a case study of two genetically and morphologically distinct wolf populations living in Eurasia. One of these survived the climate changes that have occurred over the past 40,000 years, whereas the other did not. We will describe the details of this extinction and replacement event, and determine the genetic processes that led to this difference between the two populations. To achieve this, we will carry out next-generation sequencing of wolf ancient DNA samples, and take advantage of ancient samples already collected and sequenced from across Eurasia. Together, this dataset will constitute the largest ancient wolf genome dataset ever collected. The project will end with a workshop that includes experts in climate and population viability modeling, and conservation practicioners, to explore the ways that the findings can be incorporated into future climate change mitigation planning. This workshop will provide new research avenues that the experienced researcher will be able to exploit in order to reach and reinforce a position of professional maturity and independence. The experienced researcher will also be trained in cutting edge scientific techniques and analyses, as well as a number of skills that are transferable between countries and sectors (including management, grant writing, communication and teaching), and that will facilitate his development into a research leader.

Keywords: wolf,extinction,re colonisation,climate change,selection,demographic change
Implementation of the Initiative for Global Leadership in Solar Thermal Electricity (HORIZON-STE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: Coordination and support actions
Countries involved: Germany,Spain,Italy,Türkiye,Belgium
Call: Support to the realisation of the Implementation Plans of the SET Plan (H2020-LC-SC3-2018-Joint-Actions-2, 2018)
Start date: 2019-04-01
End date: 2022-09-30
Duration (months): 42.0
Total project cost (EUR): 999656.25
EU funding (EUR): 999656.25
Participants: 5
Project status: CLOSED

Since 2007, the initial deployment of CSP/STE in Spain has brought the European STE sector to be a worldwide technology leader. But the further deployment has been hindered in Europe since 2013 due to the retroactive changes in the investment conditions in Spain. To unlock this situation, the EC has launched in 2015 a dedicated Initiative – Initiative for Global Leadership in Concentrated Solar Power (CSP). This Initiative, focusing on 2 targets (a cost reduction target and an innovation target), was adopted in 2016 within the SET-Plan structures. A working group gathering representatives from several SET-Plan countries and the STE stakeholders from both industry and research sectors was set up to define a corresponding Implementation Plan (IP), which was officially adopted in June 2017, including 12 R&D action line and the implementation of new innovative, so-called First-Of-A-Kind (FOAK) plants. Thus, as response to the call H2020- LC-SC3-JA-2-2018, this project proposal aims at supporting the full implementation of the a.m. Initiative taking into consideration the political, legislative and institutional as well as the market backgrounds put in perspective to the situation of the STE sector in 2018 – 2 years after the “Initiative” was presented and the corresponding “IP” adopted by the SET-Plan Steering Group. Building bridges to other ongoing projects (MUSTEC, SMARTSPEND, etc), the project will propose solutions and pathways for relevant countries to overcome the main shortcomings of current national strategies related to STE that are: a) for the industry the framework conditions for procurement of manageable RES, and b) for the R&I sector, the extension to more public funding agencies and other sources for the funding of a.m. R&I projects. This will result in national country reports and events as well as an EU-wide cooperation report/event to be extensively covered by national mainstream media and supported by a strong dissemination and political communication campaign.

Keywords: concentrated solar power,implementation plan,set plan