Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
EXSOLUTION-BASED NANOPARTICLES FOR LOWEST COST GREEN HYDROGEN VIA ELECTROLYSIS (EXSOTHyC)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Research and Innovation actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: Estonia,Belgium,Netherlands,Germany,United Kingdom
Call: Innovative electrolysis cells for hydrogen production (HORIZON-JTI-CLEANH2-2023-1, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 2495480.0
EU funding (EUR): 2495480.0
Participants: 5
Project status: SIGNED

Today’s alkaline electrolysers favour current densities over efficiency: to achieve commercially relevant current densities, these systems typically operate at voltages exceeding 2 V/cell, corresponding to electrolyser power consumption of >54 kWh/kg. There are four reasons for employing high voltages: 1) electrodes’ insufficient electrochemical activity, 2) the relatively high gas permeability of commonly employed diaphragms means that improved hydrogen purity can be achieved at high current operation points, 3) the stack designs are not optimised for low-current operation due to very simple flow fields, and 4) high currents are required to achieve attractive electrolyser CAPEX costs (EUR/kW). Yet, there is a growing consensus that the wider adoption of green H2 is not hindered by electrolyser CAPEX: the costs of green H2 are in most cases vastly dominated by OPEX, which in turn is a direct function of electrolyser efficiency. Thus, to achieve lowest possible levelised cost of H2, efficiency should be prioritised over current density. EXSOTHyC will optimise electrolyser operation towards lower voltages and higher efficiencies. The innovation is three-fold and addressing all four above-mentioned reasons: • Alternative pathways to the O2 and H2 evolution reactions by new anode and cathode approaches • Novel concepts of membrane electrode assemblies with integrated components • Novel cell design to enhance overall cell efficiency by integrating disruptive concepts In the project, we adopt an approach combining computer simulations, rapid prototyping, and thorough experimental validation on single cell, SRU and short stack level. In a nutshell, we will combine electrodes made using powder metallurgy with ceramic nanoparticles fabricated by exsolution, leveraging on the synergy that both methods require reducing atmospheres. Also, membrane-electrode assemblies based on Zirfon will be developed. The cell/stack will be backed by computer modelling.

Keywords: alkaline electrolysis electrode development stacks cells zirfon gas cross over catalyst coated membranes dynamic operation stability ccd
Personalized and Subjective approaches to Natural Language Processing (PERSONAE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer Science and Informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 1499775.0
EU funding (EUR): 1499775.0
Participants: 1
Project status: SIGNED

My project, PERSONAE, will make language technology (LT) accessible and valuable to everyone. I will revolutionize research in subjective tasks in NLP such as abusive language detection and sentiment and emotion analysis by developing a new field called personal NLP, yielding new datasets, tasks, and algorithms. This new research area will explore subjective tasks from the perspective of the individual as information receiver, making users active actors in the creation of LTs instead of mere recipients. This will allow for a more tailored, effective approach to NLP model design, resulting in better models overall. Each person has their own interests and preferences based on their background and experience. These factors impact their views of what makes them happy, angry, or depressed over time. Language technologies (LTs) can consider individual preferences. However, current research presumes a static view of subjectivity: that a single ground truth underlies subjective tasks such as abusive language detection, an assumption that lacks human variability and prevents universal access to LTs. Language-based AI such as virtual assistants is widely available. But despite significant scientific advances, most LT applications are inaccessible to individuals and their public's opinion has become increasingly negative. GPT-3's 2020 release boosted business-oriented applications such as copywriting and chatbots, yet few that let people improve their lives—for example, by controlling what they see on social media. This gap becomes more pronounced for subjective tasks. I will design subjective LTs that can be adapted by individuals at will over time. Based on an ambitious meta approach able to generalize from existing, disconnected work, PERSONAE will rely on fully personalizable privacy-aware algorithms that can be used by anyone. It will reveal benefits of LT far beyond those of existing systems, paving the way for future applications.

Keywords: natural language processing,subjectivity
ECL-based Infectious Pathogen (bio)SEnsor (ECLIPSE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Italy,Belgium,Germany,Switzerland
Call: EIC Pathfinder Open 2021 (HORIZON-EIC-2021-PATHFINDEROPEN-01, 2021)
Start date: 2022-05-01
End date: 2025-10-31
Duration (months): 42.0
Total project cost (EUR): 2683996.25
EU funding (EUR): 2683996.0
Participants: 10
Project status: SIGNED

Infectious diseases are a threat to mankind since their appearance in human history. Despite the advances in science and technologies, such threats are still recurrent, as recently shown by the COVID-19 pandemic in 2020 – 2021, which has revealed the urgent need for novel tools for pathogen detection that would be at the same time reliable, fast, cheap, portable and simple. The goal of ECLIPSE is to address this need, with a new platform exploiting innovative ultrasensitive protocols for the detection of pathogens. ECLIPSE builds on the combination of interdisciplinary elements to facilitate the transfer to industry, i.e., (i) ElectroChemiLuminescence (ECL) as a very sensitive transduction mechanism for realizing simple, portable and cheap devices, (ii) bio-, nano-, and supramolecular-based signal amplification structures for increasing the sensitivity, and (iii) two recognition strategies to afford high affinity and selectivity, thus leading to high reliability: the Phage-Sandwich technology for the whole pathogen, and the Surface Cooperative Hybridization technology for microbial and viral nucleic acid. We will demonstrate the feasibility and adaptability of the ECLIPSE platform with three test cases: a virus (SARS-CoV-2), a bacterium (Pseudomonas aeruginosa) and a protozoan parasite (Leishmania infantum). The platform is designed to be applied to many other infectious agents, making it a "ready for the next pandemic” technology. ECLIPSE is expected to become a game-changer in European countries, where it could be a cornerstone for fast testing and reliable tracking of infections, and in developing countries that will benefit from a cheap and simple approach to detect the many infectious diseases that affect millions of people every year. The project results will be validated and demonstrated at partners’ premisses.

Keywords: luminescence,electrochemiluminescence,nanoparticles,supramolecular polymers,diagnostics,detection of pathogens,infectious diseases,covid,virus,bacterium,parasite
Hyperdimensional Modelling of the Legal System in Digital Society (HyperModeLex)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Italy
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 2494509.0
EU funding (EUR): 2494509.0
Participants: 1
Project status: SIGNED

In 2018, the Government of New Zealand started a project called “Rules as Code”. In 2020, it proposed to OECD-OPSI the adoption of coding methodology (see Cracking Code report) to create a macro-schema of Law, legally binding, that generates legal text in natural language. It resembles a reverse engineering approach with respect to the predominant method. It is backed by legal theory and AI&Law literature, where the digitalization of Legal Sources is performed from the legal provisions, expressed in natural language, to its formal-logic representation (AI&Law, LegalXML). MIT, Stanford CodeX, Australia & Canada governments are investigating this new direction using language programming (e.g., Java, Python). The intuition seems fascinating, especially in the infosphere where digital artefacts (e.g., IoT, smart contract, AI) need consumable Law to take rapid decisions (e.g., COVID-19 pandemic) often without human intervention (e.g., bots). However, such an approach can jeopardize legal heritage, democratic principles, institutional foundations, in the context of civil-law theory and EU Law & Human Rights traditions. This approach seems to neglect 30 years of AI&Law literature, legal theory foundations, philosophy of law and language, to foster a model of technocracy and efficiency. As the topic calls for timely actions, we aim to create a solid legal theoretical framework to allow the serialization of Law in machine-consumable format while preserving legal soundness. The output is a digital legal system framework (HyperModeLex) that produces a traced process of digital law-making system, in machine-consumable format (XML, RDF, coding), legally binding, executable, suitable for connected infosphere artefacts (IoT, smart contract, software, bot) and in the meantime explicable to human, using dialogic legal design approach. We need an interdisciplinary ground-breaking project to assemble various competencies, different disciplines from human and computer sciences.

Keywords: legal informatics,ai and law,legal design,legalxml,legal semantic web,open government data,legal open access,legal interpretation theory,legal theory
TraffikGene-Tx: Targeted Peptide Carriers for RNA Delivery (TraffikGene-Tx)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Challenges
Action type: EIC actions
Countries involved: Spain
Call: EIC Transition Challenge: RNA-based therapies and diagnostics for complex or rare genetic diseases (HORIZON-EIC-2022-TRANSITION-01, 2022)
Start date: 2023-06-01
End date: 2026-05-31
Duration (months): 36.0
Total project cost (EUR): 2498963.75
EU funding (EUR): 2498963.75
Participants: 1
Project status: SIGNED

TraffikGene-Tx: Targeted and Dynamic RNA Peptide Vehicles -Unmet Clinical Need and Problem Rare and complex genetic diseases lead to significant disability, death and associated cost burdens for society. Complex genetic diseases include cardiovascular diseases (CVD) and cancer, the two leading causes of death in the EU and up to 36 million Europeans suffer from rare genetic diseases. Nucleic acid therapeutics (NATs) represent a potential treatment, but they are hampered by the “delivery problem.” Systemically administered naked RNA is quickly degraded by endonucleases, can provoke adverse immune reactions and has off-target toxicity. Viral and lipid nanoparticle (LNP) delivery vectors have toxic side-effects and are difficult to produce and target. -The Solution TraffikGene´s RNA delivery platform is: Safe: biodegradable, non-immunogenic peptide carriers that cleave to avoid the detergent toxicity of LNPs. Targetable: beyond the liver, to the spleen, lungs and heart with excellent delivery to the cytosol. Scalable: Production is automated, simple and cheap. TraffikGene combines modular design with high-throughput screening which will feed into AI-enhanced SAR-based predictive vehicle design. This will accelerate and de-risk NAT drug development. -The Project TraffikGene will capitalize on the current breakthroughs in healthcare represented by NATs. RNA therapeutics (mRNA, saRNA, siRNA, lncRNA, miRNA) are now emerging driven by the success of mRNA vaccines and TraffikGene will deliver them to the tissues where they are needed. We aim to break new ground in the field of RNA, validate our delivery vehicles and start developing our pipeline to advance to the preclinical trial stage with therapeutic RNAs. We aim to launch our company of customised peptide carriers for any RNA medicine with a proprietary flagship RNA-based immunotherapy. Our products will bring many promising NATs to the market, and help millions of patients, while reducing health care costs.

Keywords: synthetic carriers,peptide carriers,non viral vectors,rna delivery,targeting,nucleic acid therapeutics,cancer immunotherapy,melanoma
LOW-EMISSION POWER SUPPLY FOR EMERGENCY SHELTERS AND BASES OF OPERATIONS (POWERBASE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Strengthened Security Research and Innovation
Action type: Coordination and support actions
Countries involved: Germany,Austria,Sweden,France,Italy,Hungary,Slovakia,Netherlands,Greece,Portugal
Call: Open grounds for pre-commercial procurement of innovative security technologies (HORIZON-CL3-2023-SSRI-01, 2023)
Start date: 2024-10-01
End date: 2025-09-30
Duration (months): 12.0
Total project cost (EUR): 1143071.03
EU funding (EUR): 1037047.88
Participants: 13
Project status: SIGNED

During large-scale natural or manmade disasters (e.g. flooding, wildfires, earthquakes) with damaged infrastructure, access to reliable, scalable, and portable energy supply is crucial for emergency response organizations (ERO). It enables the operability of Bases of Operations (BoO) during response activities and of Emergency Shelters (ES) for the affected communities. So far, no other technology surpasses diesel generators in meeting energy supply requirements for BoO and ES, despite their negative effects, including noise, heat, and greenhouse gas (GHG) emissions. Moreover, the dependence on local fuel further impacts the already disaster-stricken areas, exacerbating resource challenges faced by local communities. To address these challenges, leveraging the advances in renewable energy (RE) technology is the key to achieving true self-sufficiency and providing a low-emission power supply for BoO and ES, while mitigating the aforementioned disadvantages. POWERBASE follows a holistic capability-driven approach to address this gap and create a community of European EROs and innovative renewable energy solution suppliers. EROs will describe and validate their unmet low-emission power supply needs in functional and operational terms. At the same time, a comprehensive State of the Art (SOTA) analysis will map market-ready and emerging RE technologies. In the following open market consultation, requirements, and SOTA will be communicated to solution providers. Through its procurement strategy and end-user driven needs, POWERBASE establishes the ground for the future adoption of existing and emerging RE technologies that can enable the transition towards a low-emission, reliable, self-sufficient, mobile power supply for ES and BoO contributing to EU Green Deal 2050 target of 55% GHG emission reduction. This transition will also significantly improve the accommodation conditions of emergency responders, sheltered people in ES, and acceptance within local communities

Keywords: renewable energy,low emission power supply,bases of operation,emergency shelter,emergency responders,crisis management,capability driven approach,pre commercial procurement,community building
Bis(carbene) Analogues of Aluminium and Gallium as Building Blocks for Highly Selective Reagents and Next Generation Catalysts (AGILE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-04-01
End date: 2030-03-31
Duration (months): 60.0
Total project cost (EUR): 1999820.0
EU funding (EUR): 1999820.0
Participants: 1
Project status: SIGNED

Molecular chemistry impacts on a wide range of transformational activities that the society relies on and thus plays a key role in addressing the societal challenges facing the European Union in the 21st century. Current synthetic methods commonly depend on rare and costly precious metals or face obstacles stemming from mismatching molecular orbitals, which necessitates atom-inefficient synthetic pathways. Hence, research on the utilisation of abundant and environmentally benign elements in synthesis and catalysis and the exploration of alternative activation and functionalisation strategies is urgently required. AGILE addresses these challenges by establishing new methods for breaking and making chemical bonds and for redox-catalysis with a single system, i.e. homo- and heterobimetallic bis(carbene) analogues of aluminium and gallium, which will be utilised as the next generation of selective reagents, high performing catalysts, and valuable ligands. AGILE will develop novel, reactive compounds that combine the benefits of derivatives in highly reactive oxidation states with the cooperativity of dinuclear Al and Ga complexes that are cheap, environmentally benign, and non-toxic. Equipped with unique frontier molecular orbitals, they will provide the reversible reactivity crucially required to unlock a wide range of elemental steps. By merging two one-electron processes, AGILE will overcome the limitations of monometallic two-electron reactions, thereby enabling redox-catalysis by main-group bimetallics. Finally, AGILE will use prototypical Lewis-acids as very strong electron donors to promote redox-catalysis with abundant first-row transition metals. In-depth kinetic, spectroscopic, and computational insight will help us achieve these challenging objectives. By providing new catalysts and expanding the scope of challenging chemical transformations, AGILE will significantly contribute to the development of main-group chemistry and more sustainable synthetic methods.

Keywords: cooperative effects bimetallic complexes main group chemistry
The Latin Church and the waning of Greek Sicily: the case of Patti (c. 1085–1266) (WaninGreek)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: TERMINATED

During Antiquity, Sicily was a part of Magna Graecia and was still a hub of Greek civilisation under the Byzantine Empire. After being taken over by the Arabs (9th c.) and then by the Normans (11th c.), Greek culture continued to thrive. However, by 1200, Sicily had undergone a near-complete Latinisation. What caused this cultural shift to occur? Despite the significant impact of the Norman Conquest and immigration from the Continent, the waning of Greek society was primarily caused by the establishment of the Latin Church. While most narrative sources overlook this major transition, the best evidence can be found in documentary sources. Although Latin charters, which primarily focus on the royal government, have been studied, it is important to also explore Greek charters, the richest source of the day-to-day processes that transformed Sicilian society. The diocesan archive of Patti (prov. of Messina) provides valuable insights into this historical transformation. In the late 11th and 12th centuries, Patti lay on the cultural frontier between the predominantly Greek northeast of Sicily and the heavily Arabised west and centre. Despite Islamic rule, a few Greek monasteries managed to survive. When the Normans took over, the Greek Church experienced a resurgence and Greek was the mostly used administrative language. However, when Sicily passed to Henry VI in 1194 and Latin became the sole language of administration, Greek culture was already in decline. WaninGreek studies the Latin Church’s role in the transition of Greek communities. I plan to produce a reference edition of the Greek charters of Patti and to use the Latin archives to produce a historical monograph. My goal is to make these sources accessible to future scholars and to provide an enlarged and detailed account of the process. Starting from a local level, I will demonstrate how cultural changes occurred during the Middle Ages and how this approach can enrich the history of the entire Mediterranean area.

Keywords: mediterranean sea multiculturalism multilingualism norman sicily byzantine sicily arabic sicily byzantine greek medieval latin palaeography