Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Baryonic Semitauonic Measurements for Beyond Standard Model Searches (BSM4BSMs)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Hungary
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-01
End date: 2027-01-31
Duration (months): 24.0
Total project cost (EUR): 157622.4
EU funding (EUR): 157622.4
Participants: 1
Project status: SIGNED

In the field of particle physics today, the search for what lies beyond our Standard Model is a long-awaited goal. My proposal will push forward this search and potentially uncover what we refer to as new physics. I will be measuring a unique decay that involves the transition of Lambda baryon to a tau lepton. This decay is an excellent avenue to test one of the main pillars of our Standard Model, an aspect referred to as Lepton Flavour Universality (LFU). Specifically, I will examine the ratio of the rates of Lambda decay to the tau lepton, as compared to the other two leptons, the electron and muon. This ratio is expected to have a value of 1 in the SM. However, similar measurements, with other parent particles, have been done at 3 other leading particle physics experiments, and a deviation from the SM expectation has been observed. As an expert in the field, I have performed one of these measurements at the Belle II experiment in a channel involving the decay of a B meson. At LHCb, I have unique access to the Lambda channel and this will allow me to perform a highly anticipated measurement in the field, one which will help complete the picture for LFU tests of the SM. Based on my wide experience at Belle II, I will perform this measurement with improved sensitivity and extend the scope of this LFU test to involve angular observables. The latter are more interesting, since contrary to the ratio, angular observables can help uncover the nature of any new physics, if it exists. To achieve my goal, I will develop a novel multivariate technique based on high-impact variables from the event information to suppress the persistent backgrounds in LHCb's noisy environment. I will also examine at new Lambda decay sub-channels, ones that have never been measured before. With my precision measurement, I will confirm or annul a persistent anomaly in the field. What ever the result, I will impact our current understanding of the origin of our universe.

Keywords: baryon particle decays,precision measurements,lepton flavour universality,standard model of particle physics,multivariate techniques,collision event information,background suppression
Resilient Multimodal freight Transport Network (ReMuNet)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Safe, Resilient Transport and Smart Mobility services for passengers and goods
Action type: Research and Innovation actions
Countries involved: Germany,Finland,Austria,Belgium,Denmark
Call: New concepts and approaches for resilient and green freight transport and logistics networks against disruptive events (including pandemics) (HORIZON-CL5-2022-D6-02, 2022)
Start date: 2023-07-01
End date: 2026-06-30
Duration (months): 36.0
Total project cost (EUR): 3998177.5
EU funding (EUR): 3997552.5
Participants: 23
Project status: SIGNED

ReMuNet identifies and signals disruptive events and assesses their impact on multimodal transport corridors. It reacts quickly and seamlessly upon disruptive events in real-time. It supports TMS-providers to improve route planning resilience. ReMuNet communicates alternative, pre-defined, multimodal transport routes to logistics operators and subsequently to truck drivers, locomotive drivers and barge captains. Through this, it enables a faster and adaptive multimodal network response. ReMuNet orchestrates route utilization, suggests transshipment points and optimizes capacity allocation, minimizing damage and shortening the recovery time. What is ReMuNet’s core objective? As trailblazer for the Physical Internet, ReMuNet pursues the vision to enable and incentivize synchro-modal relay-transport on European rail, road, and inland waterways to increase the holistic network resilience. It significantly reduces emissions and boosts freight transport corridor efficiency in case of disruptive events. How will ReMuNet achieve this? 1. A standardized method to describe multimodal transport networks. The proposed standard is derived from existing approaches and developed together with critical stakeholders to ensure Europe-wide practicability and acceptance 2. An algorithm capable of calculating multimodal route alternatives and capacity utilization in the face of disruptive events. It uses real-time data for dynamic synchromodal alternative route planning 3. A collaborative platform connecting relevant freight operators and enables them to manage disruptions. This is done by providing secure and resilient digital logistic and network management tools enabling alternative route planning information and orchestrating event-based synchromodal relay transportation 4. Using Reinforcement Learning to model and evaluate alternative courses of action, providing the basis for a self-learning, adaptive multimodal European freight transport and logistics network

Keywords: multimodal transport,resilient supply chain,disruptive event,relay traffic,synchro modal,sustainable transport,collaboration platform,route planning algorithm,self learning impact modeling
Synergistic Integration of Hyperconducting Electric Propulsion and Composite Structures with Intelligent Morphing for Hydrogen-Powered Aviation (HyperMorpH)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Clean and competitive solutions for all transport modes
Action type: Research and Innovation actions
Countries involved: Portugal,Germany,Italy,United Kingdom,Slovakia
Call: Competitiveness and digital transformation in aviation – advancing further composite aerostructures (HORIZON-CL5-2024-D5-01, 2024)
Start date: 2026-01-01
End date: 2029-06-30
Duration (months): 42.0
Total project cost (EUR): 5408094.09
EU funding (EUR): 4999397.66
Participants: 7
Project status: SIGNED

HyperMorpH focuses on hybrid-electric hydrogen-powered aircraft architectures. It suggests that as liquid hydrogen (LH2) becomes available for zero-emissions aircraft, cryogenically-cooled electric propulsion systems will become more economically viable. Advanced, sustainable composites, particularly advanced FRPs, will play a crucial role in this high-efficiency propulsion system due to their superior properties in demanding thermal and electromagnetic environments. HyperMorpH aims to develop a cryogenic ultra-light and high-power density hyperconductive electric motor using fibre-reinforced polymer (FRP) composites. Additionally, it will explore how this propulsion system can benefit from coupled aerostructure/propulsion systems integration, focusing on optimal aft-fuselage Boundary Layer Ingestion (BLI) configurations. The project will also investigate hybridization with under-the-wing H2 combustion turbine engines to enhance power supply during critical flight phases. To enable the HyperMorpH propulsion system concept, it will develop advanced composite materials, including self-morphing thermoplastic-based FRPs and metastructures, using sustainable and high-volume manufacturing techniques. Cutting-edge Artificial Intelligence (AI)-supported digital tools will facilitate multidisciplinary analysis and technology integration. The project will culminate in a laboratory-scale validation (TRL 4) of the integrated system, showcasing FRP-enabled cryocooled electric motors and next-generation self-morphing BLI propulsors, with the aim of achieving carbon neutrality in the aviation sector by 2050.

Keywords: aicraft,motor,hydrogen,advanced composites,efficiency,zero emissions,bli,cryogenic,electric,flight,digital tool,digital twin,intelligent agent,intelligence,fibre reinforced polymer
Innovative solutions to reduce AQUAculture emissions and valorize sludge through PHOsphorus and NItrogen eXtraction (AQUAPHOENIX)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Clean Environment and zero pollution
Action type: Innovation actions
Countries involved: Norway,Belgium,Netherlands,Sweden,Finland
Call: Demonstrating how regions can operate within safe ecological and regional nitrogen and phosphorus boundaries (HORIZON-CL6-2024-ZEROPOLLUTION-01, 2024)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 13545098.75
EU funding (EUR): 8999725.76
Participants: 23
Project status: SIGNED

Aquaculture faces a dilemma. Population growth, food resource constraints and increasing recognition of environmental challenges related to food production position aquaculture as a key component of a healthy diet and sustainable food source. As a result, aquaculture is the fastest growing food industry in the world - a trend that is expected to continue for years to come. However, its growth presents a series of environmental challenges including Nitrogen and Phosphorus (N+P) emissions from sludge (and consequential eutrophication of our water bodies), significant waste streams, and unsustainable feed sources. Each of these challenges are exacerbated by the fact that countries such as Norway, which produces more aquaculture products than the EU combined, aims to grow its sector by five times in the next 25 years. Important regulation that govern N+P emissions therefore limit production growth. This dilemma presents a fantastic opportunity for AQUAPHOENIX. We will demonstrate a novel SludgeCollect infrastructure in seven regional DEMO sites in Norway and Finland, which are incorporated into existing open pen aquaculture farms. Validation of SludgeCollect, together with significant political will backing our project, will pave the way for our ability to simultaneously increase aquaculture production while reducing N+P emissions to promote healthy seas. What's more, we will test and develop a variety of valorisation pathways that will commodify sludge as a circular resource for producing renewable energy, sustainable agriculture fertiliser, and novel food and feed ingredients. The AQUAPHOENIX consortium recognises its ability to respond to this opportunity and is partnering with leading aquaculture associations and networks to act as a global forerunner to lead change on a large scale. We are committed to advancing reductions in aquaculture’s N+P emissions and support the green transition towards a Zero Pollution Europe.

Keywords: aquaculture,circularity,waste management,sustainable agriculture,bioeconomy,blue economy,green transition,farm to fork,health seas,mission ocean
Next-Gen Targeted Protein Degradation: Directing Disease Proteins to the Proteasome (NextTPD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Israel
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2025-POC, 2025)
Start date: 2026-01-01
End date: 2027-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

The ubiquitin-proteasome system (UPS) is crucial for maintaining diverse cellular functions through the selective degradation of proteins. Targeted Protein Degradation (TPD) has emerged as an innovative therapeutic strategy that harnesses the UPS to selectively degrade disease-causing proteins. A major advancement in TPD is the use of proteolysis-targeting chimeras (PROTACs), small molecules that bind both an E3 ligase (E3) and the target protein, to induce ubiquitination and subsequent degradation of the target. While PROTACs have shown promise, their reliance on E3s poses challenges, including tissue-specific expression of E3s, the requirement for accessible ubiquitination sites on target proteins, and potential resistance mechanisms due to E3 mutations. Furthermore, only a small subset of E3s has been successfully utilized for TPD. To address these challenges, this ERC PoC project explores an alternative approach: direct targeting of proteins to the proteasome for degradation, bypassing the need for ubiquitination. This strategy eliminates reliance on specific E3s and provides a broader, universal approach for proteolysis. During our ERC StG project, using cutting-edge proteomics technology, we identified short peptide motifs that when fused to target proteins, can promote their ubiquitin-independent proteasomal degradation (UbInPD). These findings present a novel opportunity to design PROTACs that directly recruit targets to the proteasome, bypassing the traditional limitations of E3-based systems. Here, we aim to develop PROTACs incorporating UbInPD short peptide motifs to enhance TPD of model disease-associated proteins, such as the androgen receptor and BRD proteins, for cancer treatment. This approach could significantly broaden the scope of targetable proteins, opening up new avenues for drug discovery. Successful outcomes could lead to groundbreaking therapeutic applications and establish novel, ubiquitin-independent TPD strategies in precision medicine.
Advancing neuroscience by imaging BRAin Cortical fibErs (BRACE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1499736.0
EU funding (EUR): 1499736.0
Participants: 1
Project status: SIGNED

MRI provides the unique opportunity to investigate the relation between brain structure and function non-invasively, which is key to understand the functioning of the brain and unravel disease processes. An important technique is diffusion MRI (dMRI), which allows to reconstruct the structural connections through which brain structures communicate. Conversely, no technique can reconstruct the internal wiring of brain structures such as the cortex in living humans, where cognitive functions are processed, hindering scientific and societal progress. To achieve this, three challenges must be overcome: a spatial gap of an order of magnitude between (d)MRI and the cortical circuitry; insufficient contrast provided by (d)MRI in the cortex; and a lack of appropriate models to characterize cortical circuits. I aim to bridge the gap between structure and function by mapping the fibers of the brain cortex non-invasively for the first time, which are expected to be affected by neurodegenerative processes, and to be closely related to cognitive decline. To achieve this goal, I will pioneer a synergistic approach combining my expertise (dMRI acquisition and modelling), with unique acquisition hardware designed at our institution. First, I will establish a novel multidimensional acquisition combining dMRI with MR relaxometry, together with a signal model tailored to characterize axonal fibers in the cortex. Next, I will leverage state-of-the-art hardware and super-resolution approaches to push the boundaries of in-vivo MRI by an order of magnitude (to the mesoscale). This will unveil cortical fibers in living humans for the first time, and allow us to explore their properties in patients with Alzheimer’s disease, their changes during ageing, and their relationship with cognitive function. Altogether, we will provide a new asset to understand cognitive dysfunction in neurodegeneration, and generate novel fundamental insights for systems neuroscience.

Keywords: brain structure and function,connectivity,fiber tractography,diffusion mri,brain cortex
Restorative Effects of Haptic and Visual Sensory Supplementation of Nature Sounds in VR of Nature for Deaf people (ReSens-Nature)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Cyprus
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-02
End date: 2026-09-01
Duration (months): 24.0
Total project cost (EUR): 148488.0
EU funding (EUR): 148488.0
Participants: 1
Project status: TERMINATED

Exposure to nature and its sounds can relieve from stress, promote relaxation, and restore cognition. These restorative benefits persist even with exposure to Virtual Reality (VR) of nature and its calming sounds. It is the combination of visual and auditory exposure to these VR environments and their sounds that promotes restorative effects for hearing people. This means that Deaf and Hard-of-Hearing (HoH) people may be excluded from being able to receive the same restorative benefits that hearing people receive. Evidence shows that there can be cross-modal transfer in HoH people, whereby speech and sounds can be perceived and understood through vibrations on the skin or can be localised via visual cues in VR technologies. Through the ‘ReSens-Nature’ project, the Fellow will develop a novel VR experience, through which he will examine the restorative effects of vibrotactile and visual sensory supplementation of nature sounds in VR nature environments for Deaf/ HoH people. The objectives are to (i) Develop and establish the usability of this novel VR nature environment that uses vibrotactile and visual supplementation of nature sounds, (ii) Examine whether this novel VR nature environment is providing restorative benefits to Deaf/ HoH people in comparison to a regular VR nature environment without sensory supplementation and in comparison to hearing people. Understanding the effects of sensory supplementation for Deaf/ HoH in VR nature environments could help make VR and other technologies more inclusive for Deaf/ HoH people and people with other disabilities. The project will be completed at the GET Lab of Cyprus University of Technology, a world-leading lab on VR technology and Wellbeing. The Fellow will bring highly complementary expertise in Deafness, Audiology, and Clinical Trials. The proposed work will advance the Fellow’s research and management skills, expand his research networks, and enhance the development of his career as an independent researcher.

Keywords: deaf wellbeing nature
A network of excellence for distributed, trustworthy, efficient and scalable AI at the Edge (dAIEDGE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: A human-centred and ethical development of digital and industrial technologies
Action type: Research and Innovation actions
Countries involved: Germany,Belgium,France,Bulgaria,Spain,Norway,Italy,Ireland,Sweden,Finland,Netherlands,Switzerland,United Kingdom,Poland,Greece
Call: European Network of AI Excellence Centres: Expanding the European AI lighthouse (RIA) (HORIZON-CL4-2022-HUMAN-02, 2022)
Start date: 2023-09-01
End date: 2026-08-31
Duration (months): 36.0
Total project cost (EUR): 10746872.0
EU funding (EUR): 10746872.0
Participants: 38
Project status: SIGNED

The proposal focuses on the Next Generation AI topic of the call HORIZON-CL4-2022-HUMAN-02-02. The vision of dAIEDGE Network of Excellence (NoE) is to strengthen and support the development of the dynamic European edge and distributed Artificial Intelligence (AI) ecosystem as an essential ingredient in the growth and competitiveness of European industrial sectors. The dAIEDGE Network aims to reinforce the research and innovation value chains to accelerate the digital and green transitions through advanced edge AI technologies, applications, and innovations, building on Europe's existing assets and industrial strengths. In parallel, it will fortify the edge AI research and industrial communities through technological developments beyond state of the art and become a dependable and strategic pillar for the European AI Lighthouse. This will be achieved by mobilising and connecting the European AI and edge AI constituency, the relevant stakeholders, European partnerships, and projects, to provide roadmaps, guidelines and trends supporting the next-generation edge AI technologies. The key aim is to support and ensure rapid development, market uptake and open strategic sovereignty for Europe in the critical technologies for distributed edge AI (hardware, software, frameworks, tools). The dAIEDGE NoE will play a catalyst role in building a solid edge AI virtual network of research facilities and laboratories to benefit the European research and industrial community. The NoE multidisciplinary concept provide an arena for matchmaking, exchanging ideas, tools, and services, by bringing together the leading research centres, AI-on-demand platforms, digital innovation hubs, AI projects and initiatives. The ultimate goal for the dAIEDGE NoE is to support Europe to become a global centre of excellence with unique human-centred edge AI competence addressing the social and economic challenges and the needs of the citizens and society.

Keywords: edge ai,network of excellence centers