Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Sustainable Photovoltaics Integration in buildings and Infrastructure for multiple applications (SPHINX)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: France,Italy,Germany,Netherlands,Belgium,Switzerland,Spain
Call: PV integration in buildings and in infrastructure (HORIZON-CL5-2023-D3-01, 2023)
Start date: 2023-11-01
End date: 2026-10-31
Duration (months): 36.0
Total project cost (EUR): 6221886.75
EU funding (EUR): 5247990.98
Participants: 14
Project status: SIGNED

Europe's ambitious target of reducing greenhouse gas emissions by 55% by 2030 presents a significant challenge, and addressing it requires innovative solutions. The SPHINX project aims to accelerate the adoption of photovoltaics, the cheapest source of energy, by developing new photovoltaic products for integrated construction that are multi-functional, aesthetically pleasing, and have a minimal impact on resources such as land and materials. SPHINX aims to demonstrate solutions for an economic and sustainable integration of five innovative PV products in five respective demonstration sites covering different construction typologies: lightweight modules for installation on rooftops with weight constraints, tiles for heritage buildings, tiles for facades, semi-transparent modules for carports, and noise barriers. Each of these products will be piloted and monitored to demonstrate high energy production, low degradation rates, competitive installation costs, and a low environmental impact. To increase the efficiency of solar modules, SPHINX is leveraging a disruptive European interconnection technology known as matrix shingling. This technology improves the filling of the active area of solar modules, leading to a 3% increase in power output, and make them less sensitive to shading. This translates to up to 3 times more energy yield compared to standard modules under strong partial shading. Furthermore, this technology drastically reduces the use of resources such as lead and copper. To further enhance module performance, SPHINX will add new functionalities to the encapsulant, including UV selective absorption and reemission for power increase, selective reflection of IR light to increase bifacial boost, and reduce temperature behind the panel. New coatings will also be developed to provide anti-glare and anti-fouling capabilities based on a new deposition process that can be reapplied in the field in case of damage.

Keywords: matrix shingle,lighweight,antiglare,antifouling,bipv,pilot line
Metal-containing Radical Enzymes (MetRaZymes)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Netherlands,France,Austria,Italy,Germany,Switzerland,Denmark,United Kingdom
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2022-10-01
End date: 2026-09-30
Duration (months): 48.0
Total project cost (EUR): 2406624.0
EU funding (EUR): 2406624.0
Participants: 26
Project status: SIGNED

The pharmaceutical, chemical and polymer industries are cornerstones of Europe’s economy. A key element for their transition to more sustainable processes and to innovative new compounds is biocatalysis. Of particular interest are metallo-enzymes, i.e. proteins that host a metal cofactor. They catalyze a multitude of redox and radical reactions. To access reactions that are unknown in nature, artificial metallo-enzymes can be created. They combine the new-to-nature catalytic activity of metal complexes with the selectivity-inducing environment of the active protein site. To develop novel biocatalysts, a highly interdisciplinary skill set is needed. MetRaZymes will create a PhD school across leading European universities that will train the next generation of scientists capable of tackling the design, development and implementation of novel enzymatic reactions in a holistic approach. It brings together computational bioscientists, bioinorganic and polymer chemists, and bioprocess engineers. Using artificial and repurposed metalloenzymes as the focal point, the ESRs will develop novel biocatalysts for radical reactions of high synthetic value, such as the late stage modification of pharmaceutical intermediates or the synthesis of polymers from renewable monomers. To train the ESRs in the needs of industrial biotechnology, the consortium includes eight of Europe´s leading pharmaceutical, chemical and enzymology companies. The ESRs will benefit from a vast transferable skills training program delivered by five training partners. Highlights include a Nature Masterclass and Wikipedia workshop. Communication partners such as Wikimedia and the Industrial Biotechnology Innovation Centre will act as muliplicators for the communication of results. Moreover, the ESRs will work with artist that use biology as their way of expression to create an ARTzymes exhibition that will foster the ERS´s creativity and result in a an unique form of science dialogue with the general public.

Keywords: artificial metalloenzymes,non native biotransformations,radical chemistry,radical polymerizations,directed evolution,protein engineering,computational biochemistry,bioprocess engineering
Breaking frontiers of Eddy Current Testing simulations through Discrete De Rham methods (EffECT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

Eddy Current Testing (ECT) is an industrial procedure used to assess the reliability of the most critical facilities of nuclear power plants. Prior to practical usage, ECT requires a delicate phase of calibration and validation via numerical simulations. However, in the current state-of-the-art, they are limited by two critical issues: the poor precision of the results, and the limited geometrical modeling flexibility. This project will use the recently introduced Discrete de Rham (DDR) simulation method to overcome at once both these issues, focusing on three specific aims: laying the mathematical foundations of DDR methods for ECT simulation, building the practical computational tools to implement this method in a simulator, and using the simulator on real-life ECT scenarios. The project has a strong multidisciplinary nature, involving a combination of numerical analysis and engineering, and its originality and innovation lie on this interdisciplinary approach. The mathematical analysis of DDR methods for ECT is a complete novelty and represents a mine of mathematical problems in numerical analysis. The development of the EffECT simulation (open-source) will require both the transfer of the candidate’s engineering knowledge to the host institution and the training of the candidate on the very specific DDR mathematical methods. The project will thus make the candidate able to speak to different communities, improving his career prospects as an independent researcher. The planned communication activities of the project will target people both inside and outside academia, helping the latter to appreciate the effectiveness of the interaction between fundamental mathematical research and engineering in solving real-life problems. The arising results have the potential to increase the safety and efficiency of nuclear power plants and open new horizons in fundamental and applied level of numerical analysis of DDR methods, as well as other cutting-edge simulation methods.

Keywords: discrete de rham methods,finite element methods,polytopal methods,eddy currents,electromagnetism
Diversification: Causes, Consequences, and Welfare Effects (DICACO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-06-01
End date: 2030-05-31
Duration (months): 60.0
Total project cost (EUR): 1740452.0
EU funding (EUR): 1740452.0
Participants: 1
Project status: SIGNED

DICACO analyses causes, consequences, and welfare effects of diversification, once equilibrium effects that affect investor welfare and side effects that affect consumers and taxpayers are considered. The analysis informs the question: Is cheap diversification good for society? Sub-projects investigate (i) Theory: whether benefits of diversification that accrue to individual investors viewed in isolation also benefit investors in equilibrium, once effects on asset prices are considered; (ii) Empirics: to which extent diversification motives drive “common ownership” of product market competitors; (iii) Theory and empirics: whether bidding behavior in government procurement auctions depends on whether bidders are owned by diversified investors, how much taxpayer money is inefficiently transferred to shareholders as a result, and how procurement auctions could be redesigned to re-claim efficiency losses caused by diversified ownership of bidders; (iv) Theory: how predictions on portfolio choice, equilibrium ownership, asset prices, firm behavior, and product prices depend on jointly endogenizing all these variables, and how this equilibrium depends on the implementation of policy proposals that seek to restrict investor diversification. We use tools from general equilibrium theory and numerical computer simulations in (i) & (iv); machine learning and reduced-form econometrics in (ii); auction theory and structural estimation in (iii). The project develops new methods to solve equilibrium asset pricing models and for auction theory. The uniquely comprehensive dataset on corporate ownership will be open sourced for academic research worldwide. Because of the potential to shift beliefs, the provision of new tools for academic research, and because policy makers might erase trillions of Euros of economic gains by enacting the wrong policies, overall, the risks of the project are justified by the high gains for both researchers and policymakers.

Keywords: diversification,competition,governance,common ownership
A molecular atlas of Actin filament IDentities in the cell motility machinery (ActinID)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: B iological  Mechanisms , Structures  and Functions
Panel description: For all organisms : Molecular biology , biochemistry, structural biology, molecular biophysics , synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-04-01
End date: 2028-03-31
Duration (months): 60.0
Total project cost (EUR): 1499531.0
EU funding (EUR): 1499531.0
Participants: 1
Project status: SIGNED

The actin cytoskeleton is essential to cellular function and hence to life. It is regulated not only via a complex synergistic and competitive interplay between actin-binding proteins (ABP), but also by filament biochemistry and filament geometry. Both the biochemical identity of an actin filament as well as the geometrical identity of actin networks are defined by ABP activity, while biochemistry and geometry also regulate ABP recruitment. However, it is still unknown how actin filament biochemistry, geometry and ABP activity jointly define actin cytoskeleton remodelling in a dynamic system such as cell migration. Resolving this critical relationship would enable a better understanding of the multitude of cellular processes that ultimately depend on actin. ActinID will tackle this question by advancing in situ structural biology to generate a molecular atlas of the actin cytoskeleton proteome in migratory cell protrusions. Our overarching aims are to: 1) Develop: cryo-electron tomography workflows to achieve 3D imaging of entire actin networks in cellular protrusions at single-filament resolution, combined with detailed quantitative analysis. This will provide the ground truth on how dynamic filament geometries steer directional cell movement. 2) Solve: high-resolution in situ structures of ABPs and F-actin and describe ABP quantity, ABP distribution and spatial correlation with their potential partners. This visual proteome will reveal how actin filament identities are regulated in an entire system. 3) Study: the reciprocal regulation of ABP activity, filament geometry and biochemistry via (genetic) manipulation of ABPs using integrative cell and structural biology experiments, and relate this to cell migration characteristics. ActinID will be transformative for our understanding of actin cytoskeleton regulation, while also advancing the potential of in situ structural biology to go beyond isolated structural descriptions of biological systems.

Keywords: structural biology,actin cytoskeleton,visual proteomics,cryo electron tomography,image processing,method development
A HOLISTIC APPROACH TOWARDS HIGH QUALITY URBAN WATER THROUGH EFFECTIVE MONITORING AND URBAN WATER MANAGEMENT PLANNING (QleanUP)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Clean Environment and zero pollution
Action type: Innovation actions
Countries involved: Netherlands,Greece,United Kingdom,Spain,Belgium,France,Switzerland
Call: Holistic approaches for effective monitoring of water quality in urban areas (HORIZON-CL6-2024-ZEROPOLLUTION-02, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 5468287.5
EU funding (EUR): 4999998.75
Participants: 16
Project status: SIGNED

Urban water is confronted by global challenges such as climate change and emerging anthropogenic substances. As such, protecting urban water quality requires a proactive approach that increases the urban water system resilience and their surrounding ecosystems. Thus motivated, the overall objective of QleanUP is to deliver a water quality management platform that will incorporate: 1) Stakeholder engagement; 2) sensors and techniques to monitor levels of existing and emerging pollutants, 3) digital tools to estimate difficult to measure pollutants and understand and predict the spread of pollution, 4) risk-based urban water quality management plans and holistic water quality monitoring. The objective will be reached by demonstrating a compendium of modular, complementary innovative solutions, including novel real-time (soft-) sensing and water quality measurements, easy to deploy decision tools that support resilient, evidence-based operational awareness of urban water systems and risk-based interventions. In line with the EU zero pollution action plan, QleanUP aspires to increase the resilience of urban water systems in terms of both increased robustness (against short term stresses) and adaptability (against longer term uncertainties) and ensure high-quality urban water, minimising nutrients, heavy metals, (pathogenic) micro-organisms, including anti-microbial resistance (AMR), organic micropollutants (OMPs), including PFAS, and microplastics. To test and validate the efficacy of the urban water management platform, the developed tools and strategies will be demonstrated across five (5) Demo Cases in Switzerland, Spain, Greece, the Netherlands, and the UK, supported by co-creation activities and stakeholder engagement.

Keywords: integrated management of water,water pollution,digital services
Unlocking the Potential of Dredged Sediments : Towards Sustainable Geopolymers for Green Construction (UP-RISE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Norway,Canada
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-02
End date: 2026-09-01
Duration (months): 24.0
Total project cost (EUR): 226751.04
EU funding (EUR): 226751.04
Participants: 2
Project status: SIGNED

Climate change poses a global challenge, and the production of cement contributes significantly to greenhouse gas emissions (GHG) by 5–8%. This project is, therefore, poised to revolutionize the industry by developing an innovative, eco-friendly cement using dredged materials (DMs) as precursors to produce greener geopolymers. The latter are synthesized by mixing materials rich in aluminosilicates with an alkaline solution. The GHG of geopolymer concrete is ~73% and ~46% less than ordinary Portland cement (OPC) concrete, respectively. Geopolymers exhibit noticeably improved mechanical properties compared to OPC concrete and have been shown to have better resistance to acid attacks, high temperatures, and fire. However, the production of large quantities of geopolymer concrete is limited due to the declining availability of fly ash worldwide. Dredged sediments have been identified as a potential source of silica and alumina. This project sets out to establish the foundational science needed to transform DMs into materials suitable for structural applications, thus pioneering a sustainable path to CO2 reduction. This study will foster the adoption of these by-products in sustainable infrastructure development and create a roadmap for producing DM-based geopolymers. The research, led by me, Dr. Amine el Mahdi Safhi, under the mentorship of Dr. Mahdi Kioumarsi and Dr. Shima Pilehvar at Østfold University College (HiØ) in Norway, will bolster my skills in materials and structural engineering, preparing me for an expansive academic career. The project is an international endeavor, with the collaboration of Dr. Ahmed Soliman from Concordia University (Canada) and industrial partner NETICS (Netherlands). Our vision is to turn an environmental challenge into an opportunity for sustainable development. By harnessing DMs, we will not only transform the cement industry but also positively impact society and the environment.

Keywords: construction materials geopolymers dredged sediments sustainability circular economy
Clocking the conduction velocity of the visual pathway with optically pumped magnetometers (OptiVision)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-01-01
End date: 2026-06-30
Duration (months): 30.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

The human visual pathway carries high volumes of information from the retina to distant regions of visual cortex. The speed of this information transfer, retinocortical conduction time, has been proposed as a diagnostic measure of neurodegeneration. This conduction time has typically been estimated based on relatively slow evoked responses, although we now know that high-frequency activity in both the retina and visual cortex precede slower evoked responses by several tens of milliseconds. In addition, the difference in timing between the onset of high-frequency activity in the retina and cortex is more in line with the expected conduction velocities of the heavily myelinated visual pathway. This project proposes to develop and validate a new sensor technology, optically pumped magnetometers (OPMs), to measure this high-frequency retinocortical conduction time, with a view towards establishing a diagnostic suitable for patients in the neurology and eye clinics to assess disease progression. Impacts to myelination, circulation, and neural connectivity are all expected to reduce the conduction speed of the visual pathway, even before visual symptoms become apparent. The proposed high-frequency conduction time technique should provide a more accurate and sensitive measure to detect these impacts, with high potential for translation into a clinical diagnostic method. We will furthermore streamline the measurement procedure to increase the comfort, duration, and feasibility for potential patient groups.
A TRUSTworthy speech-based AI monitorING system for the prediction of relapse in individuals with schizophrenia (TRUSTING)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Staying Healthy in a rapidly changing society
Action type: Research and Innovation actions
Countries involved: Netherlands,Switzerland,Australia,Spain,Norway,Türkiye,Czechia,Belgium,France,Hungary,Ireland
Call: Trustworthy artificial intelligence (AI) tools to predict the risk of chronic non-communicable diseases and/or their progression (HORIZON-HLTH-2022-STAYHLTH-01-two-stage, 2022)
Start date: 2023-07-01
End date: 2028-12-31
Duration (months): 66.0
Total project cost (EUR): 5999510.0
EU funding (EUR): 5999510.0
Participants: 13
Project status: SIGNED

Schizophrenia affects a staggering 21 million people worldwide, with 80% of these citizens suffering from a relapsing disease, putting their health and safety at enormous risk. Timely detection of these psychotic relapses would require very frequent contact with clinicians, which is neither desirable nor feasible. An accurate online relapse predictor could alert clinicians of subtle deterioration, which enables timely intervention and allow safe discontinuation of long-term medication, which so many affected citizens desire. Our Consortium demonstrated that subtle alterations in speech carry a predictive signal for psychosis onset. This project will develop an AI monitoring system that leverages spoken language processing (SLP) and natural language processing (NLP) of speech recorded at home to calculate the relapse risk. The monitoring tool we develop will be validated retrospectively in a longitudinal cohort, cross-sectionally, across six languages, after which it will be tested prospectively in a multicenter randomized trial, with the end goal of improving functional and clinical outcomes of those affected by schizophrenia. Developing such a system for exceptionally vulnerable people requires ‘buy-in’ from clinicians and mental health care service users, namely trust. A lack of trust is the biggest obstacle to the real-world implementation of a speech-based monitoring system. TRUSTING will develop a framework that systematically ensures addressing all the criteria for trustworthy AI put forward by the EU. This will ensure an empirically based and validated tool that can reliably detect pending relapse. As the core philosophy of trustworthiness is part of every aspect of the project, it will be a system more likely to be welcomed and embraced by service users and their carers. TRUSTING generates the scientific and social foundation for disruptive technology to deliver the unmet promise of an equitable and just form of healthcare for people at risk of relapse.

Keywords: natural language processing,spoken language processing,speech,psychosis,schizophrenia,relapse prevention,human in the loop,ai tool,online monitoring