Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Tracing connectivity via ceramic technology in riverine environment of the Middle Danube Region during the Ottoman period (DANUBE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Serbia
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2025-06-15
End date: 2027-06-14
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 2
Project status: SIGNED

DANUBE aims to study cultural connectivity among potters in riverine environment of the Middle Danube Region during the 16th-17th centuries, which is a phenomenon of central importance for an archaeological interpretation of cultural change in Central Europe initiated with the Ottoman expansion. This interdisciplinary study combines archaeological and scientific analyses of common pottery with an anthropological theory on technology and written sources of the Ottoman period to reconstruct the ceramic production technology and means of knowledge transmission along the Danube-Sava-Drava rivers. Common pottery included in DANUBE is part of six largely unstudied archaeological collections from Serbia and Croatia, and this project aims to highlight existing potentials of the Middle Danube Region for archaeological studies of the post-medieval period. Focusing on pottery consumed in riverine settlements after the Ottoman conquest, the project explores links between ceramic morphology, technology and cultural connectivity. DANUBE is the first study of riverine connectivity in Post-Medieval Archaeology of Central Europe. Although DANUBE deals with a specific region, it can be used as an exemplar for addressing broader cross-cultural and methodological questions regarding the role of rivers for networks of knowledge exchange and connectivity in the context of large-scale migrations, military pressure and cultural change. The project introduces the regional-scale approach to ceramic studies in the Middle Danube Region and goes beyond ceramic morphology to explore human interactions along large rivers of Central Europe. DANUBE benefits from the applicant’s sound research experience crosscutting archaeological and scientific studies of Ottoman ceramics in Southeastern Europe, combined with the access to materials from riverine sites and the prospect for synergies and expertise at the University of Tübingen.

Keywords: post medieval archaeology,cultural connectivity,ceramic analysis,riverine environment,ottoman archaeology,central europe,ceramic petrography,chemical analysis
State-tech relations in the datafied welfare state: Examining the computational transformation of the European social model (STATETECH)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-04-01
End date: 2031-03-31
Duration (months): 60.0
Total project cost (EUR): 2498705.0
EU funding (EUR): 2498705.0
Participants: 1
Project status: SIGNED

Use of data-driven technologies by public bodies is now well-established across central pillars of European welfare states, from predictive benefit fraud in social security to safeguarding apps in schools to algorithmic diagnostics in health. Yet we still lack a proper understanding of what the datafied welfare state entails, and, crucially, what its relationship with the providers of such technologies is, and with what implications. This project investigates the relationship between the welfare state and digital technology providers in the context of data-driven innovation and explores what this means for a European social model. It is premised on two significant assumptions: 1) the relationship between digital technology providers and the welfare state is qualitatively different from previous and other forms of service provision; and 2) the European social model is transitioning towards a socio-technical model that has implications for welfare state functions. STATETECH investigates four lines of enquiry: a) governmentality; b) infrastructure; c) rentierism; and d) political regulation in order to assess a new institutional formation I refer to as the ‘tenant-state’. It explores both pan-European tendencies as well as specificities across different welfare regimes and is groundbreaking in five different respects: i) it situates computational transformations of the European social model in context by testing theories of new forms of state; ii) it connects ongoing debates in critical data studies with political and economic sociology around the future of the welfare state; iii) it addresses an uncharted but rapidly emerging shift in government relations with service provision; iv) it combines archival research with socio-technical modes of investigation to inform analysis of computational transformations; and v) it maps and advances (new) imaginaries and practices of state-tech relations suitable for a transition towards a European socio-technical model.

Keywords: critical data studies
Proteomics of neuroinflammatory signaling: Illuminating cellular mechanisms driving neurodegenerative diseases (NEUROINFLAM-MS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-12-01
End date: 2026-11-30
Duration (months): 24.0
Total project cost (EUR): 230774.4
EU funding (EUR): 230774.4
Participants: 1
Project status: SIGNED

Alzheimer’s (AD) and Parkinson’s disease (PD) are prevalent neurodegenerative diseases, but their underlying mechanisms remain poorly understood. Emerging evidence suggests that neuroinflammation, characterized by the release of pro-inflammatory cytokines like IL-1β, TNF-α, and INF-γ, plays a pivotal role in these diseases, challenging the conventional focus on protein aggregates (Aβ, αSyn). In AD, it has been shown that elevated IL-1β levels induce the translocation of NEDD8 from the nucleus to the cytoplasm, where it co-localizes with the E3-ligase Parkin. Together with the kinase PINK1, Parkin is crucial for the removal of defective mitochondria, with loss-of-function mutations in these genes being the primary cause of early-onset PD. Intriguingly, phosphorylated NEDD8 can activate Parkin, implicating a more complex interconnection between neuroinflammation, NEDD8-and Parkin-regulated phosphorylation-dependent signaling in brain cells. Yet, a mechanistic understanding of cellular processes triggered by neuroinflammation remain elusive. This proposal aims to investigate spatiotemporal (phospho-)proteome changes in response to neuroinflammatory stress elicited by pro-inflammatory cytokines and αSyn fibrils. To achieve this, I will combine spatial-proteomics using subcellular fractionation and hybrid-DIA in combination with the cutting-edge Orbitrap Astral mass spectrometer. Initial analyses of neuronal cell line models will be extended in a second step to hPSC derived neurons, astrocytes, microglia, and co-cultures thereof. This enhances the translational relevance by mimicking neuroinflammation in the complex tissue architecture of the brain. Finally, bioinformatically shortlisted neuroinflammation-regulated proteins and phospho-sites will be validated in cell-based models. With this project, I aspire to unravel the cellular mechanisms underlying neuroinflammation, potentially unlocking new avenues for therapeutic strategies against neurodegenerative diseases.

Keywords: phospho proteomics,nedd8,neuroinflammation,spatial proteomics,hybriddia ms,cellular signaling,kinase signaling,hpscs,co cultured brain cells,il 1,tnf,inf,synuclein
Astaxanthin Metabolism in Salmon: A Cutting-Edge Multi-Omics Exploration (SAXOmics)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-10-31
Duration (months): 30.0
Total project cost (EUR): 314473.2
EU funding (EUR): 314473.2
Participants: 3
Project status: SIGNED

Astaxanthin (Ax) is crucial for achieving the pink-red hue in farmed Atlantic salmon, a key quality factor at sale. Since salmon cannot produce Ax naturally, it is added to their feed. Beyond pigmentation, Ax's antioxidant properties may boost salmon growth and health. However, farming challenges have led to a decline in muscle Ax levels, possibly due to rapid growth, welfare challenges, and low retention rates. Despite Ax's high cost and its importance in fish feed, retention in salmon remains low, under 12%. Improving Ax retention and pigmentation is a key challenge in salmon aquaculture, essential for the industry’s growth and salmon health. The SAXOmics project aims to enhance understanding of Ax metabolism, focusing on its absorption, transport, and retention, to improve Ax retention, feed and fish quality, and address pigmentation challenges. Enhancing Ax absorption and retention is crucial, as dietary lipids and other factors promote Ax retention, though the exact molecular mechanisms are not fully understood. Recent research suggests that gut microbiota affect lipid metabolism, pointing to a possible role in the Ax mechanism. By employing a groundbreaking interdisciplinary approach that integrates multi-omics technologies and advanced bioinformatics tools, this project will delve into the molecular mechanisms of Ax metabolism and develop innovative feed formulations to optimize Ax absorption, transport, and retention. The project will include enterocyte and muscle cell culture and salmon pigmentation trials, complemented by thorough training in omics technology, animal ethics, experimental design, and scientific communication. Joint efforts with Nord University, NTNU, and BioMar will support practical applications and commercialization of the findings. By month 30, I will have advanced expertise in salmon rearing and nutrition, practical omics skills, and a strong network, positioning me as a competitive candidate capable of driving innovation in my field.

Keywords: astaxanthin,salmon,cell culture,gut microbiome,omics techniques
Distributional Effects of Circular Economy Policies: a CGE-based framework for redistribution (DECEP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: France,Switzerland,Netherlands
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-10-31
Duration (months): 26.0
Total project cost (EUR): 300772.96
EU funding (EUR): 300772.96
Participants: 3
Project status: SIGNED

This project aims to analyse how Circular Economy (CE) transitions may affect income distribution and welfare across socio-economic groups. With global material use expected to double in 40 years, reliance on material resources for economic growth raises sustainability concerns. CE offers an alternative by promoting resource efficiency, waste reduction, and material reuse, potentially leading to more sustainable economic growth. Despite the growing importance of CE, there remains a critical gap in understanding its distributional effects, particularly its effects on economic inequality and welfare. While some economic models have been developed to assess the effectiveness of CE policies, they overlook the redistributive dimensions of these transitions. This project seeks to fill this gap by developing a Computable General Equilibrium (CGE) model that integrates both welfare and inequality analysis in the context of CE policies. Building on the work of two string of literature: 1) on CGE modeling which investigate redistributive polices and 2) on CGE modeling of the CE, this project will apply state-of-the-art CGE modeling to assess how CE transitions may affect socio-economic groups. It will explore dynamic scenarios of policy interventions, measuring the effects on income distribution, resource use, and overall welfare. The project's objectives include developing a comprehensive CGE model to analyze CE's effects on redistribution, calibrating the model using relevant economic data, and providing policymakers with actionable insights on how to design equitable and efficient CE policies. Ultimately, this project will provide insights into designing policies that balance socio-economic objectives with environmental sustainability. It will contribute to a deeper understanding of how to ensure that the shift towards a CE is not only resource efficient but also socially equitable, minimizing the risks of increased inequality.

Keywords: computable general equilibrium modeling income inequality welfare analysis resource efficiency circular economy sufficiency
CR-Yamabe problem, Kähler metrics and K-stability (CRYamKmetKstab)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-02
End date: 2026-09-01
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

One of the main questions in Differential Geometry is the existence of special metrics, that is, a way to measure distances, on smooth manifolds. They are the basic objects in Differential Geometry, and can be thought of as geometric objects that can be locally approximated by the usual flat space. The goal of CRYamKmetKstab is to investigate the existence of these special metrics on complex manifolds from the point of view of Complex Differential Geometry, by employing techniques that come from Differential Geometry, Algebraic Geometry and Geometric Analysis. More precisely, we propose a novel way to approach constant scalar curvature Kähler metrics by drawing a connection between the so-called CR-Yamabe problem and K-stability of the manifold.

Keywords: special k hler metrics,einstein hilbert functional,sasaki geometry,k stability,fano varieties
High Energy Density Asymmetric hybrid supercapacitors for applications in consumer goods and electrification (HEDAsupercap)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Portugal,Poland,Sweden,Italy,Ukraine,Belgium
Call: Novel materials for supercapacitor energy storage (RIA) (HORIZON-CL4-2022-RESILIENCE-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 5519470.0
EU funding (EUR): 5519470.0
Participants: 8
Project status: SIGNED

Supercapacitors are considered important energy storage devices that can complement batteries for various applications. While currently the electric double-layer capacitors (EDLCs) still dominate the market, their low energy density cannot satisfy the ever-increasing demand. The HEDAsupercap project aims at developing high energy density asymmetric hybrid supercapacitors consisting of two dissimilar EDLC-type and battery-type electrodes. The improvement of energy density will be accomplished through the asymmetric cell design and developing novel materials and components, including electrode materials, ionic liquid electrolytes and current collectors. Sustainable, environmentally-friendly, and cost-effective synthetic approaches will be employed to ensure the elimination of critical raw materials (CRMs) usage and the minimisation of environmental impact during the components production. Supercapacitor cells and modules comprised of newly developed compoents, along with innovative management system, will be developed and demonstrated in electric scooters for last-mile mobility as well as in hand warming gloves for sport & leisure. Comprehensive techno-economic and value chain analyses will be carried out, and a business case and exploitation strategy will be developed by the end of the project to roadmap future commercialisation of the HEDAsupercap technology. The HEDAsupercap consortium comprises three research & technology organisations, two universities, and three leading companies in the automotive, energy and engineering sectors. This will allow the developed technology to be quickly taken up and adopted in the market. The HEDAsupercap project will promote widespread deployment of high energy density hybrid supercapacitors in mobility and consumer goods sectors. The project results will be disseminated to different stakeholders, raising their awareness of the latest development of this new technology.

Keywords: asymmetric supercapacitors,electrification,high energy density,porous carbon,metal phosphide positive electrode,ionic liquid,management system,life cycle cost analysis,market analysis
Evaluation of lesion network mapping as a technique to identify therapeutic targets for brain disorders (NetworkStim)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy,Finland
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-02
End date: 2026-07-01
Duration (months): 22.0
Total project cost (EUR): 158354.24
EU funding (EUR): 158354.24
Participants: 2
Project status: SIGNED

Disorders of the brain are a major source of disability, and place an enormous burden on society. Currently, many first-line treatments are non-specific, invasive, or cause side-effects. Non-invasive brain stimulation techniques, such as repetitive transcranial magnetic stimulation (rTMS), have been shown to offer a safe treatment alternative, with rTMS first clinically approved for major depression in 2007. Unfortunately since then, translation to other disorders has been slow, mainly due to the lack of reliable methods to identify where in the brain to stimulate. Lesion network mapping (LNM) is a method recently introduced to address this problem. LNM works by mapping the connections of causative brain lesions, converging upon a small number of commonly connected locations in the brain. LNM has localised abnormal networks in over 40 different disorders. However, as yet no study has tested whether these networks respond to treatment. Therefore, the aim of this study is to conduct a clinical trial testing whether rTMS delivered to a specific site in the somatosensory cortex identified in our previously published LNM study (Corp et al., 2019, Brain) results in treatment benefit for cervical dystonia patients. Cervical dystonia is an ideal test case, as changes in abnormal neck movement symptoms are easily measurable, and this somatosensory location is on the surface of the brain, so easily reachable with rTMS. We will employ a randomised, sham-controlled, double-blind, crossover clinical trial, with 30 patients receiving 10 daily sessions of real and sham rTMS. Before and after the brain stimulation, we will collect clinical, behavioural, and physiological data to measure patients’ response to the intervention. Improvement in cervical dystonia symptoms after brain stimulation would serve as proof of the principle that LNM can effectively identify therapeutic targets, potentially unlocking safe and effective treatment protocols for a range of brain disorders.

Keywords: lesion network mapping,brain stimulation,transcranial magnetic stimulation
Strategic Information: New Directions and Applications (SInfoNiA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: France,United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 1152586.25
EU funding (EUR): 1152586.25
Participants: 2
Project status: CLOSED

In a world saturated with data, the role of information as a coordination device for economic activity is more and more central, and impacts phenomena such as financial crises, currency attacks and social stability. Although the importance of information as a driving force is well established, current models of coordination and robustness are limited to the restricted class of binary actions supermodular games. Following recent methodological advances of the PI as a proof of concept, the project offers a model of strategic types that will define the role of information in general strategic situations. Our methodology diverges from the conventional approach by reframing all information in relation to the game under study. Rather than considering information description as a distinct entity separate from the game itself, our approach centers on strategically relevant information within a particular, predetermined game context. SInfoNiA will create new foundations for the analysis of information in economics, and delve into new positive and normative implications of the theory as described in 7 work packages (WP). The first 4 WPs are methodological, they provide a model of strategic types for a wide array of games (WP1), develop new avenues to the measure and value of information (WP2), unify strategic types with global games information structures (WP3), and offer algorithms that will allow for wide applicability and dissemination of the methods (WP4). WP5 utilizes these methods to expand the global games frontier and to analyze new models of financial stability, while WP6 will offer a broad analysis of the robustness of economic outcomes, including in trade and financial networks. WP7 takes a normative approach and provides joint design of information structures and incentives that efficiently implement desirable outcomes. It offers informational interventions to bring on changes in social norms, in particular in gender inequality.

Keywords: information structures,bayesian games,robust economic predictions,information design,global games,higher order beliefs