Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Valorization of CO2 for low carbon cement (CO2Valorize)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Germany,United Kingdom,Denmark,Slovakia
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2022-09-01
End date: 2027-04-30
Duration (months): 56.0
Total project cost (EUR): 2359083.77
EU funding (EUR): 1932297.6
Participants: 11
Project status: SIGNED

Cement production is responsible for 8% of global CO2 emissions, which mainly come from the processing of limestone. CO2Valorize proposes a new approach to drastically reduce these emissions by partly replacing some of the limestone content with supplementary cementitious materials (SCM). Such materials are additionally carbonated using captured CO2, so this part-replacement process utilises captured CO2. Promising, calcium silicates rich SCM can come from waste materials such as mine tailings and recycled concrete, all of which are available in large quantities. The carbonation process of such materials is complex and barely understood to date. Our networks aim to lay the scientific foundations to create fundamental knowledge on the mechanisms, reaction kinetics, the physico-chemical subprocess, and the performance of the modified cement in order to provide a proof-of-concept and show that a CO2 reduction by 50 % per tonne of cement produced is feasible. The project is driven by leading companies that represent important parts of the value chain and ensure a fast uptake of the results with the potential to commercialise new equipment, processes and software during and after the project. The structured approach combines complementary research for each individual project in the academic and industry sector. This is accompanied by a balanced mix of high-level scientific courses and transferable skills delivered by each partner locally and in dedicated training schools and workshops at network level. This way, each doctoral candidate builds up deep scientific expertise and interdisciplinary knowledge to deliver game-changing cleantech innovations during and after the project. CO2Valorize is impact-driven and strives for portfolios of high-class joint publications in leading journals and patents. The transfer of the results into first-of-its-kind engineering solutions contribute to the next generation of cement processes that can mitigate climate change.

Keywords: carbonation,cement industry,carbon dioxide,mining industry,technoeconomic analysis,flow sheet simulation
Oncogenic competence during development – When, Where and Why? (ONCO-COMP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1499943.0
EU funding (EUR): 1499943.0
Participants: 2
Project status: SIGNED

Childhood cancers are believed to be rooted in aberrant development, a notion supported by their (i) generally low mutational burden, (ii) high prevalence of single (often epigenetic) driver events and (iii) occurrence during confined developmental periods. Yet, the exact origins of developmental tumours remain one of the principal enigmas of pediatric oncology. A prime example are malignant rhabdoid tumours (MRTs): they are astoundingly genomically simple but extremely deadly childhood cancers that arise almost exclusively in the first two years of life, and are driven by biallelic inactivation of the SWI/SNF chromatin remodelling complex subunit SMARCB1 (>95% of cases). We still do not know what determines oncogenic competence upon SMARCB1 loss. In particular we wonder: (1) What are the cell(s)-of-origin of rhabdoid tumours and what is their normal differentiation potential? (2) What is the molecular framework that facilitates oncogenic transformation upon SMARCB1 loss? (3) What is the contribution of the niche (local and systemic) to the acquisition of oncogenic competence? And, considering the epigenetic nature of the oncogenic event, (4) is the oncogenic MRT state reversible, and how? To answer these questions, we will combine state-of-the-art lineage-barcoded single-cell genomics, spatial transcriptomics, single-cell resolution wholemount imaging, CRISPR/Cas9 and epigenomic approaches, as well as integrative computational analyses, using transgenic mouse, induced pluripotent stem cell and patient-derived xenograft rhabdoid tumour models. This project will provide fundamental insights into the cell autonomous and non-autonomous determinants of oncogenic competence upon SMARCB1 loss. Based on our findings we hope to unlock targeted treatments for MRT patients. Importantly, the conceptual and experimental framework we establish will open up new investigative opportunities for a multitude of developmental cancers.

Keywords: oncogenic competence,epigenomics,rhabdoid tumours,chromatin,lineage tracing,developmental tumours,prime editing,cell of origin,tumour initiation
SpatioTemporal Reconstruction of Interacting People for pErceiving Systems (STRIPES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer Science and Informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-02-01
End date: 2030-01-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

People constantly interact with objects to perform tasks. To help people accomplish these, computers need to perceive Human-Object Interactions (HOI), and for this, they need to reconstruct HOI from whole-body color images of people interacting with objects or scenes. This is challenging, due to the occlusions between bodies and objects, motion blur, depth ambiguities, and the low image resolution of hands and graspable object parts. There has been significant prior work on estimating 3D humans without considering objects, and estimating 3D objects without considering humans. Little prior work estimates these jointly, but, for tractability, focuses either on interacting hands, ignoring the body, or on interacting bodies, ignoring hands. Only recent work addresses dexterous interaction of whole bodies, but instruments bodies with intrusive markers or sensors, and uses non-standard cameras to capture video of interactions. Moreover, reconstruction lacks hand detail that is crucial for grasping, and videos are captured in constrained settings, consequently, methods trained on these struggle generalizing. My goal is to infer HOI from natural whole-body images/videos. To this end, I present an ambitious 5-year research agenda with novelties in four directions: (1) developing strong generative 3D shape models for objects and humans for a novel HOI representation; (2) developing methods that estimate 3D HOI from a color image with rich contact and proximal awareness; (3) instilling spatiotemporal reasoning into the heart of these for estimating 4D HOI from color video; and (4) extending these methods to also infer their own confidence that will be correlated with the reconstruction quality. The outcome will be novel and robust methods for HOI reconstruction from natural images/videos. This will fill an important gap, enabling future intelligent systems to amplify people’s skills and help them accomplish tasks, e.g. for assistive robots or virtual 3D assistants or trainers.

Keywords: 3d computer vision,3d 4d reconstruction,3d digital humans,3d human object interaction,3d human scene interaction
Redox flow batteries charging tomorrow’s world through the in-depth understanding and enhanced control over battery hydrodynamics (RECHARGE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1498614.0
EU funding (EUR): 1498614.0
Participants: 1
Project status: SIGNED

Electrochemical energy storage is essential if we wish to increase the usage of intermittent energy sources such as windmills and solar panels. With intermittent energy sources it is crucial that energy can be stored to meet demand when production is too low. When targeting stationary storage with large capacity and long storage times, redox flow batteries stand out. However, in order to compete with other energy storage technologies several fundamental challenges remain to be resolved. Mass transport limitations, cell resistivities, pressure losses and slow kinetics still pose major barriers that result in unsatisfactory energy efficiencies and power densities. In RECHARGE, I propose an innovative and disruptive approach. By combining for the first time pulsatile flow with precisely structured 3D electrodes the battery’s performance can be accurately steered towards improved battery hydrodynamics, allowing to surpass state-of-the-art in terms of maximum attainable power density, diminished efficiency losses and enhanced energy capacity. The combination of targeting an in-depth understanding into how reagent, product and electrolyte transport is governed within the redox flow battery by using in operando characterisation and having perfect control over the electrode geometry and flow field design through advanced engineering approaches, will result in unprecedented control over the mass transport and reaction environment. This will yield a significantly improved redox flow battery with a power density of 1000 mW/cm² and a roundtrip efficiency above 85%. RECHARGE will demonstrate the impact of achieving perfect control over the hydrodynamic and electrochemical characteristics of a redox flow battery and can thus be considered as the first step towards a new generation of redox flow batteries that will completely redesign the electrode structure and fluid control strategies towards strongly improved battery efficiencies.

Keywords: redox flow battery electrochemical engineering pulsatile flow 3d electrode
Augmenting and Evaluating the Physical and Digital Infrastructure for CCAM deployment (AUGMENTED CCAM)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Safe, Resilient Transport and Smart Mobility services for passengers and goods
Action type: Innovation actions
Partnership: CCAM (co-programmed)
Countries involved: Belgium,Ireland,Greece,Germany,Sweden,Austria,Czechia,Spain,Slovenia,France,Italy,Latvia,Switzerland
Call: Physical and Digital Infrastructure (PDI), connectivity and cooperation enabling and supporting CCAM (CCAM Partnership) (HORIZON-CL5-2021-D6-01, 2021)
Start date: 2022-09-01
End date: 2026-04-30
Duration (months): 44.0
Total project cost (EUR): 11134645.21
EU funding (EUR): 8999808.13
Participants: 27
Project status: SIGNED

AUGMENTED CCAM aims to understand, harmonise and evaluate in an augmented manner adapted and novel support solutions of Physical, Digital and Communication (PDI) infrastructure, to advance its readiness for large scale deployment of CCAM solutions for all. The project will elaborate, extend and harmonise PDI classification and support levels mapping co-determined PDI priority requirements and adaptations. Based on this and by deploying an open sharing technology agnostic service operational framework and architecture for PDI enabled CCAM, addressing all CCAM actors via multi-cooperation models, the project will develop 11 PDI support solutions (aiming at TLR 6-7) that will apply and evaluate in different configurations in seven (7) test sites across three (3) European Countries (France, Latvia, Spain), encompassing a vast spectrum of physical (living labs, closed areas, open traffic highway, urban and peri-urban/rural environments) and virtual (DT, AV & driving simulators) test beds. AI and Big Data advanced techniques and crowdsourced HD maps will leverage the whole transport system and its users’ situational awareness, prediction and actuation. The different test activities findings, supported by micro and macroscopic traffic simulations, will allow the assessment of different PDI support on functional safety of the whole transport infrastructure, on traffic safety and efficiency, driving behaviour, environmental footprint, service reliability, trust & security, considering the socioeconomic benefits and costs of all actors, and the issue of roadmap and recommendations, proposing risk-aversion decision making tools and methodologies for policy making and CCAM - ready infrastructure investments. AUGMENTED CCAM, coordinated by FEHRL, consists of a multi-stakeholder Consortium of 26 Partners from 12 European countries and one Associated partner from Switzerland. Roughly 50% of them are firms (30% Industries, 50% of which road operators, and 18,5% of them SMEs).

Keywords: physical and digital infrastructure,ccam,digital twins,operational design domain,infrastructure support for automated driving,pdi classification and support schema,service architecture
SUSTAINABLE JET FUELS FROM CO2 BY MICRO-ALGAL CELL FACTORIES IN A ZERO WASTE APPROACH (ALFAFUELS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Sweden,Germany,Denmark,Netherlands,Italy,Spain,Belgium,Greece
Call: Development of algal and renewable fuels of non-biological origin (HORIZON-CL5-2022-D3-03, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 5147500.29
EU funding (EUR): 4757391.33
Participants: 14
Project status: SIGNED

ALFAFUELS proposes a novel Sustainable Aviation Fuels (SAF) production technology that can play a major role in the decarbonisation of the aviation sector by replacing conventional fossil fuels in mid and long-term. ALFAFUELS contributes to climate change mitigation, energy transition, and on the establishment of a circular bio-based economy by providing a direct capture and utilisation of CO2, by developing cost-effective and sustainable technological solutions in all process steps, and by providing integration possibilities with other sectors. The project’s aim is to tackle the key challenges preventing SAF technologies to reach technological maturity and commercialisation such as the high current production cost, sustainability issues associated with their production, technological constraints (yields and efficiencies). To that end, ALFAFUELS includes targeted technological breakthroughs, such as the microbial production of a volatile fuel precursor from CO2, the upgrade to kerosene-type jet fuel molecules in ambient conditions using solar light-driven photochemistry, and the valorisation of all cell components in a biorefinery approach to co-produce starch and H2 (indirectly from CO2) as an important intermediate. The proposed technological novelties are combined with modelling approaches to maximize efficiencies, to optimize the overall process regarding cost and energy consumption and to evaluate the process with combined techno-economic and life cycle assessments. The project lifts the production technologies at TRL5, by including the design of novel cost-efficient bioreactors, pilot scale trials on real, industrially relevant CO2 streams and evaluation of the produced molecules against ASTM standards. To further accelerate the upscaling of ALFAFUELS, we analyse the systemic barriers and opportunities for the implementation of SAF technologies in Europe, using modelling tools and capitalizing from the participation of industrial end-users in the consortium.

Keywords: cyanobacteria photo chemistry micro algae metabolic modelling metabolic engineering isoprene
The evolution of long-necked dinosaurs of Africa before the Cenomanian-Turonian extinction (EvoSaurAf)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United States,Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-06-01
End date: 2025-05-31
Duration (months): 36.0
Total project cost (EUR): 261380.64
EU funding (EUR): 261380.64
Participants: 2
Project status: SIGNED

The overall research goal of this proposal is to develop a multidisciplinary study of the little known long-necked dinosaurs of North Africa using virtual paleontology techniques (developed in my PhD thesis) histological data on the fossil material, pneumatic apparatus reconstruction and phylogenetic analysis to understand the significance of a range of new species. The project will have a major impact in the fields of paleontology and biology, generating critical new data on the large terrestrial vertebrates of a major continent during a period of the Mesozoic that experienced sea level and temperature changes resulting in major extinctions. The fossil material comprises the single largest undescribed fauna from any major continent during the latter half of the Mesozoic. The high-profile scientific results to come from this research over two-years in the Department of Organismal Biology (University of Chicago), under the supervision of Prof. Sereno, will boost my academic profile and experience in the fields of paleontology and evolution, significantly increasing the chance to continue my career by leading a multidisciplinary and diverse research group in the field of paleobiology in Europe.

Keywords: dinosauria,sauropoda,extinction,phylogenetics,
Build and Extend CBRN-E related Hazard-Assessment and Anomaly Detection Capabilities on Urban Environment. (BEHOLDER)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Fighting Crime and Terrorism
Action type: Innovation actions
Countries involved: Netherlands,Hungary,Poland,France,Italy,Belgium,Finland
Call: CBRN-E detection capacities in small architecture (HORIZON-CL3-2024-FCT-01, 2024)
Start date: 2025-06-01
End date: 2028-05-31
Duration (months): 36.0
Total project cost (EUR): 6582498.75
EU funding (EUR): 5877873.75
Participants: 14
Project status: SIGNED

BEHOLDER revolutionises urban security through an integrated and cost efficient platform for real-time detection, assessment, and response to CBRN-E threats. The project addresses the challenges posed by the lack of standards and integration capabilities in current CBRN-E detection systems. Its innovative approach combines IoT-enabled sensors, advanced AI anomaly detection, and seamless integration with smart city infrastructure. The key objectives include the detection of CBRN-E threats in public spaces through IoTisation, the improvement of vulnerability assessments for law enforcement, the enhancement of modelling capabilities for resource planning, and the fostering of market uptake through stakeholder engagement. BEHOLDER utilises cutting-edge technologies such as SmartFurniture, environmental sensor networks, and specialised detectors like IMS+FP, HoloZcan-IoT, RadNano, and BME688 sensors. The project's methodology emphasises a collaborative and capability-driven agile approach, involving stakeholders from the outset. Real-world pilots in urban environments will demonstrate the system's effectiveness, paving the way for wider adoption. By addressing the evolving threat landscape and enhancing urban security, BEHOLDER aims to create safer, more resilient, and better-prepared environments for all. This translates to substantial economic savings, potentially preventing millions of euros in losses from disruptions to critical infrastructure and public services. In a simulated chemical attack scenario in Eindhoven, BEHOLDER could save an estimated €259 million by reducing fatalities, injuries, and healthcare costs. Moreover, the project’s proactive approach fosters a sense of security among citizens, promoting greater public confidence and resilience. By enhancing preparedness and response capabilities, it contributes to safer, more resilient, and economically vibrant urban environments across Europe.

Keywords: chemical,biological,radioactive,nucleair,citizen protection,protection of public space,threat detection,iot,sensoring,smart furniture,security by design,safety by design,cpted