Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Uncovering the roots of harsh parenting (HARSH)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Italy
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 1992656.0
EU funding (EUR): 1992656.0
Participants: 1
Project status: SIGNED

Harsh parenting (HP) is the use of corporal or emotional punishment to discipline children. Despite harming children both physically and psychologically, it is widespread and persistent in certain regions and demographic groups. Why? Existing studies on the causes of HP predominantly focus on individual and family factors, ignoring wider contextual factors influencing childrearing practices. Motivated by an ecological framework, HARSH marks a paradigm shift in understanding HP by explicitly exploring cultural, institutional, and economic causes for the first time. It has four main related objectives: 1) Uncover the ancestral cultural origins explaining long-term HP persistence. 2) Identify the causal impact of economic factors. 3) Assess the influence of institutional structures and policies. 4) Unpack the mechanisms through which these contextual factors shape HP. HARSH reaches its goals in four transformative ways. a) Focusing on Europe and sub-Saharan Africa, leveraging on their differences in socio-economic development, stages of demographic transitions and HP prevalence. b) Utilizing new highly disaggregated data across space and time enabling analysis of HP variations within and between countries, ethnic groups, and cohorts. c) Employing innovative methodologies including spatial analysis, and quantitative economic techniques, which are uncommon in studies on violence against children, but crucial to derive causal pathways. d) Identifying innovative socio-economic mechanisms, as well as the population subgroups most at risk. HARSH pioneers new research avenues by offering unique, hypothesis-driven, empirical insights into the wider factors behind HP needed to fully grasp the reasons why parents adopt it. It offers an interdisciplinary perspective by using novel methods to test hypotheses from demography, psychology, and medicine. It supplies key scientific evidence for devising effective policies to tackle this major yet often hidden public health issue.

Keywords: child health domestic violence family demography parenting style applied econometrics survey methods health economics
Molecular Ecology of Medieval European Landscapes (MEMELAND)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: United Kingdom,Switzerland,Austria,Czechia,Norway
Call: ERC SYNERGY GRANTS (ERC-2024-SyG, 2024)
Start date: 2025-07-01
End date: 2031-06-30
Duration (months): 72.0
Total project cost (EUR): 13537645.0
EU funding (EUR): 13537645.0
Participants: 5
Project status: SIGNED

MEMELAND will pioneer the creation of Europe's first species-level ecological history, spanning the Roman era to the present day. Our research will unveil the persistent medieval influences in contemporary landscapes and biodiversity. This historical insight will inform proactive land management, conservation, and heritage-informed restoration, crucial for climate change mitigation. Our approach involves sedimentary ancient DNA (sedaDNA), lipid biomarkers, multi-method chronologies, and archaeobotanical analysis at 50 strategically selected lake-pairs across northern and central Europe within three archaeological zones. Additionally, we will go deeper in time and investigate medieval landscape-lake interactions in 3 of the lake pairs. We'll reveal species-level biodiversity, for plants, animals (livestock, fish, birds and invertebrates) and plants-animal-soil pathogens (hologenomic level). Additionally, we'll explore sub-species and landraces within critical taxa (e.g. cereals and domestic livestock). The geography of present biodiversity is a testament to medieval and early-modern agronomy, population, elite influence (lordship, ecclesiastical), cultivation systems (open-field system), technology (heavy plough) and natural ideologies. By using pairs of lakes, one associated with a high-status site and a nearby lakes with little archaeology, we'll generate geographically representative biodiversity data. This data will enable us to test hypotheses against archaeological, pollen and climate records, and reveal the geographic reality of the ‘medieval agricultural revolution’. Recent advances in sedaDNA analysis, and molecular preservation in temperate climates make MEMELAND a groundbreaking project in both Archaeology and European ecological history. Our work promises to reshape our understanding of the historical interplay between culture and nature and provide critical insights for sustainable land management and climate change mitigation in Europe.

Keywords: medieval archaeology,human ecodynamics,vegetation history,sedadna,biomarkers,landscape history,biodiversity,palaeolimnology,historical ecology,heritage management
A First of a kind Hub for circularity demonstrator for Attica and peripheral regions (Theseus)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Innovation actions
Partnership: Processes4Planet (co-programmed)
Countries involved: Greece,Germany,Sweden,Belgium,Spain,Norway,Denmark,United Kingdom,Switzerland
Call: Hubs for circularity for industrialised urban peripheral areas (Processes4Planet partnership) (IA) (HORIZON-CL4-2024-TWIN-TRANSITION-01, 2024)
Start date: 2024-12-01
End date: 2029-11-30
Duration (months): 60.0
Total project cost (EUR): 21777067.5
EU funding (EUR): 19994307.0
Participants: 53
Project status: SIGNED

Industrial-Urban symbiosis (I-US) involves municipalities and regions cooperating with industries on the management of resources, waste, energy, water, infrastructures, services, transportation and networks. This inter-disciplinary and cross-sectoral character is implemented by Hubs4Circularity (H4C) in a FOAK approach, as key instruments for delivering territorial I-US solutions in Europe by Processes4Planed partnership. Theseus will establish first-of-a-kind H4C in Greece originating from the capital region of Athens/Attica (incl. Athens metropolitan area -Greek capital, 68 municipalities, 2.928 km, 3,7 million inhabitants 35% of national- several industrial and semi-urban areas) towards the whole country, with overarching aim of closing loops through I-US to become climate neutral by 2050, in line with P4P partnership objectives. Theseus will validate new or existing technologies and develop solutions for water, energy and materials based on regional needs (Innovation Pillar (IP) 2 , 3) and digital/robotic technologies (IP4). The hub will operate under innovative governance and cooperation models of involved stakeholders, to enable pilots, upscale solutions, exploit outcomes, attract further companies and expand existing ecosystem (IP1,5). Water, energy and material flows were targeted selected, being widely spread, having high potential all over Europe and included in EU/P4P strategies. The overall systemic, based on regional science approach and IP1,IP5 activities will ensure strong insights to smoothly replicate Theseus solutions to other EU regions. Several existing innovations from H4C, I-US and Circular Cities and Regions Initiative (CCRI) projects will be used, retrofitted and expanded.. The systemic solution of Theseus is expected to have significant impact on the region, while metaphorically recalling the mythical figure of Theseus, king and great reformer of Athens.

Keywords: i us,is,h4c,digitalization,robotics,collaboration,replication,attica
Data-driven AI-assisted digital framework for enhancing circularity in manufacturing (DATA4CIRC)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Made in Europe (co-programmed)
Countries involved: Spain,Germany,Romania,Italy,Austria,Portugal,Japan,Greece
Call: Technologies/solutions to support circularity for manufacturing (Made in Europe Partnership) (RIA) (HORIZON-CL4-2024-TWIN-TRANSITION-01, 2024)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 5663837.5
EU funding (EUR): 5663836.26
Participants: 14
Project status: SIGNED

The DATA4CIRC project aims to enhance circularity within the manufacturing sector to facilitate decarbonisation whilst improving competitiveness and boosting the adoption of R-strategies. These objectives will be achieved by providing the sector with the proposed DATA4CIRC solution, a human-centred collaborative digital framework that leverages the power of data and cutting-edge digital technologies for assets digitalisation. This framework will comprise (A) Federated Data Spaces, (B) Digital Models of the circular value chains and products; (C) Digital Product Passport (DPP); and (D) an AI-assisted end-to-end LCA tool. The integration of these tools into a single framework will improve data interoperability and accessibility, therefore boosting the collaboration and the establishment of circular value chains. To do so, (E) ontologies and semantic models will be leveraged and proper user-friendly interfaces will be developed. Furthermore, the DATA4CIRC solutions will be based on existing standards and architectures to maximise their adoption and impact. Special focus will be placed on social aspects for the transition to circular business models which prioritise the needs, expectations and experiences of end-users. By embracing the social innovation paradigm, human involvement throughout the project is boosted through co-creation and co-validation activities. Moreover, an upskilling and reskilling training programme will be designed and conducted to facilitate the uptake of digital tools in the manufacturing workforce during the project and beyond its completion. Validation and demonstration of the DATA4CIRC solution will be achieved via three use cases, thereby consolidating successful progress from TRL4 to TRL6. The selected use cases are circular value chains in manufacturing sectors with high impact potential and significant room for improvement regarding the field of circular economy: the electronics, plastics, and automotive sectors.
Computationally driven discovery of organic dyes for photoredox catalysis from physicochemical principles and mechanistic information (ORGhvCAT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium,United States
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2025-09-30
Duration (months): 36.0
Total project cost (EUR): 290444.16
EU funding (EUR): 290444.16
Participants: 2
Project status: CLOSED

Photoredox catalysis has become a quintessential part of organic synthesis and gained wide interest in the chemical industry as a mild and robust synthetic methodology. Acridinium salts are a prominent substitute for transition metal-based photocatalysts (PCs) due to the modularity of the core, which makes them and structurally related dyes an optimal platform for structure-property tuning. However, a limited understanding of how structure influences reactivity prevents rational design, while the synthetically realizable chemical space is far too vast to explore using even high-throughput experimental methods. The objective of the proposed action is to study computationally the elementary mechanistic steps integral to photoredox catalysis to establish how they are each influenced by PC structure. We will develop an automated workflow for high-throughput computational molecular PC construction and analysis, in which known molecular fragments are coupled together by chemically precedented steps. Finally, Bayesian optimization will be used to guide the machine learning model building. This is distinct from conventional approaches in the field as we aim to increase the quality of our model with mechanistic understanding from quantum chemical calculation. My expertise in the fields of synthetic, physical, and computational organic chemistry, provide me the necessary skillset and ability to learn new concepts and successfully execute this project. The gained knowledge and results from the project will be an asset and help to build sustainable processes in the chemical industry in EU. The work will be implemented in the research groups of Prof. Robert Paton and Prof. Jeremy Harvey, with a secondment period in the group of Prof. Abigail Doyle. The investigators’ combined expertise ranges from computational and empirical reaction mechanism study to data sciences, and hence enables the project to incorporate complex mechanistic information to rational PC design.

Keywords: organic dyes,dft,dual nickel photocatalysis,bayesian optimization
Memory dependent PAth Sampling methods for understanding long TIMEscale molecular processes (PASTIME)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Belgium
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Time matters: timescales determine the fate, behavior and functionality of living matter. Especially the interplay between fast and slow molecular processes is omnipresent in biochemistry (protein folding, enzymatic conversions, molecular signaling, etc.). However, in chemistry, models are lacking to properly understand time and its effect on this difficult biological reality. PASTIME will lay the methodological foundations for a correct understanding of time in chemistry by introducing memory dependent transition interface path sampling to chemical modeling. We will tune the memory that is kept in simulations by creating new path ensemble definitions. The problem will be made computationally solvable by cutting molecules' pathways short. Long timescale effects will be studied through pathway statistics. We will achieve higher decorrelation in the sampling by designing new Monte Carlo moves in path space, such as alchemical moves that change the identity of atoms on the fly, and smart use of memory expansion with a replica exchange move. These new time concepts will be challenged and experimentally validated in a context of drug transport kinetics: drug (un)binding to protein binding sites, and permeation of molecules through cell membranes. The modeling principles will be converted to new algorithms that are computationally feasible today and will be shared in open software. With PASTIME we will be able to understand slow time effects in molecular interactions. Appropriate memory reduction and tuning will give us the methods to understand time in an endless range of molecular processes, and this work will contribute to drug design, biochemistry, physiology, catalysis, material and polymer science.

Keywords: molecular modeling,statistical physics,molecular dynamics simulations,sampling of phase space,monte carlo sampling,binding kinetics,binding and unbinding kinetics of protein ligand,binding sites,drug transport,drug delivery,retention time,timescales,mutations,screening,liposomes,phospholipids,membrane permeability,permeation,lipid flipflop,membrane asymmetry
A 3D-printable biomimetic bone regeneration material (PRIOBONE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-01-01
End date: 2025-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Critical-size bone defects do not heal spontaneously over the patient’s lifetime and cause substantial individual, societal and economic burden. Current treatment options are hampered by associated complications, poor functional or aesthetic outcomes, a limited availability of tissue for bone grafts, and high financial costs. Worldwide, more than 4 million surgeries per year require bone grafts or substitute materials. Consequently, there is a significant clinical and economic need for novel treatments for critical-size bone defects. In PRIOBONE, we propose the validation and steps towards exploitation of our newly developed, bone-mimetic 3D-printable material for bone repair. Our PRIOBONE material has the potential to outperform current treatments and alternative solutions on the market due to its biomimetic composition, excellent cytocompatibility, osteoinductive capacity, ideal mechanical properties, and its 3D printability into any desired shape. This allows us to create implants optimized for clinical and individual patient needs. This includes, e.g., the possibility to print the material into foldable and deployable 3D designs that allow a minimally invasive insertion of the material into defect sites, where it can re-expand. The use of well-established components and our “materials-only” approach will enable a faster track to clinical application and regulatory approval in comparison to approaches containing biologicals such as cells or previously unknown components. In PRIOBONE, we will validate our material for bone regeneration, undertake a comprehensive market analysis, explore target leads and transfer pathways, and elaborate our IP strategy towards commercialization. Following successful validation, we expect that PRIOBONE will provide a cost-efficient, individualizable alternative to current treatments with the potential to significantly lower the economic, individual and social burden of critical-size bone defects.
aCtive sEcurity foR connecTed devIces liFecYcles (CERTIFY)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Increased Cybersecurity
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Germany,Ireland,Belgium,Switzerland,France,Greece
Call: Improved security in open-source and open-specification hardware for connected devices (HORIZON-CL3-2021-CS-01, 2021)
Start date: 2022-10-01
End date: 2025-09-30
Duration (months): 36.0
Total project cost (EUR): 3997897.5
EU funding (EUR): 3997897.5
Participants: 13
Project status: SIGNED

Cyber-attacks get more sophisticated every day, thus affecting a large number of IoT-related infrastructures and raising security and privacy concerns of consumers and businesses. Security management of IoT infrastructures encompassing full lifecycle of products and continuous certification are fundamental tools to guarantee a high-level of security, as emphasized by the European Union Agency for Cybersecurity (ENISA) Cybersecurity Act (CSA). CERTIFY defines a methodological, technological, and organizational approach towards IoT security lifecycle management based on (i) security by design support, (ii) continuous security assessment and monitoring (iii) timely detection, mitigation, and reconfiguration, (iv) secure IoT Over-The-Air (OTA) updating, and (v) continuous security information sharing. To ensure the security compliance throughout the lifetime of the device, we propose the design and implementation of a cybersecurity lifecycle management framework for IoT devices. The framework is intended to support the device security management by collecting and sharing relevant security information both internally (via monitoring and self-assessment services) and externally, e.g., by interacting with device manufacturers, threat databases, certification authorities, Information Sharing and Analysis Centres (ISACs), and more. The received information is meant to support the local decision making with respect to the security, monitoring, updating and configuration of the device. Moreover, this information sharing will enable a continuous risk assessment, gathering evidence that could agile future certifications. CERTIFY's provides IoT stakeholders with mechanisms achieving high-level of security. CERTIFY will detect and respond to a wide spectrum of attack, in a collaborative/decentralized fashion. CERTIFY will validate the architecture through cutting-edge use-cases and pave the way towards innovative security in a broad spectrum of IoT environments.

Keywords: certification