Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Genetics of Mental Illness (GMI)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: The Human Mind and its complexity
Countries involved: Netherlands
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-02-01
End date: 2013-10-31
Duration (months): 57.0
Total project cost (EUR): 2466923.0
EU funding (EUR): 2466923.0
Participants: 2
Project status: CLOSED

Mental disorders put a great burden on society and their impact on personal life can be devastating. Most mental disorders begin in childhood or adolescence and co-occur with somatic disease. In children, the most common problems are ADHD and anxious/depression and these problems often co-occur with additional behavioral and emotional problems. In adults, depression is the major mental disorder. It frequently co-occurs with anxiety disorders, substance abuse, migraine, cardiovascular disease and its associated risk factors. Indeed, depression is the largest cause of nonfatal disease burden in Western countries and increasingly in low and middle income countries worldwide as well. This application focuses on the genetics of common mental disorders, co-morbid traits and diseases across the lifespan. Its primary aim is the discovery of developmental paths into risk of depression and co-morbid disorders, using genetic epidemiological, molecular genetic and gene-environment interaction models. The introduction of multivariate and longitudinal models, in particular methods introduced by my group, into these areas will lead to substantial increases in power to unravel the contributions of genotype, environment and their interactions. The project described in this application addresses three interrelated topics: 1. Neuropsychiatric disorders and cognition 2. Depression, anxiety, substance use, abuse and dependence 3. Depression, migraine and cardiovascular risk As a connecting methodological framework it will develop models for the genetic analysis of these complex traits, especially gene-environment interaction and genome-wide association models. My ambition is to discover which genes influence the risk for mental disorder and co-morbid biomedical traits, to identify the causal variants, and to explore their interaction with environmental risk factors.

Keywords: depression,adhd,personality,comorbidity,methodology
Advanced ultrafast electron sources for quantum optics experiment with free electrons (ULTRAFASTELECTRONS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2008-10-01
End date: 2012-09-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

This proposal aims at the development of an electron source that will allow controlling the position of free electrons with extremely high precision in space and time. Such a tool will enable novel quantum optics experiments and might turn into an electron source widely used in time-resolved scanning electron microscopy and electron diffraction, a field in which Europe is currently trailing the US. The proposed experiment will be a complementary effort to the applicant’s research that he is currently setting up with a Max Planck Junior Research Group Grant. After his PhD work in T.W. Hänsch’s group the applicant spent four years as postdoctoral researcher at Stanford University and returned to Europe in November 2007. The proposed experiment will transfer much of the applicant’s experience from the US and is based on the combination of a special field emission tip he developed in the US and a femtosecond laser oscillator. Femtosecond laser pulses hit the tip and so emit electrons from nanometric dimensions within timescales of a femtosecond. The final goal is a deterministic electron source, where one and only one electron is emitted with every laser pulse. Such a source would immediately enable classic quantum optics experiments. Advanced emitters will be used that exhibit quantum behaviour such as single atom tips and carbon nanotubes where emission takes place from a single or few atoms only. The proposed work would ideally augment the experiments that the applicant will perform with the Max Planck funds and will initially go in parallel to these. Proposed experiments will potentially allow highly increased visibility of his research and will help him to take the next step towards a faculty position at a respected research institution in Europe. Furthermore, expected results will strengthen research in Europe in an underrepresented field, will be relevant to the applicant’s former host at Stanford and will lead to continued collaboration on a peer level.

Keywords: quantum optics,femtosecond laser,field emssion,electron microscopy,ultrafast electron imaging,surface physics,novel materials,carbon nanotube
Market Integration and the Welfare of Europeans (INMARWEL)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: The study of the human past
Countries involved: Italy
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-09-01
End date: 2013-08-31
Duration (months): 48.0
Total project cost (EUR): 880800.0
EU funding (EUR): 880800.0
Participants: 1
Project status: CLOSED

The proposal aims at mapping the long-run process of integration of the European and world markets, from the early modern period to present, and at assessing its effects on the welfare and on institutions. To this aim it will collect a comprehensive data-base on prices, which will then be made available on-line to scholars. These data will be then used to estimate the gains from integration (or losses from disintegration). Last but not least, the project will consider some case-studies of political reactions to integration (e.g. after the Napoleonic wars) and of changes in institutions

Keywords: market integration,welfare effects
The Transformation of Global Health Governance: Competing Worldviews and Crises. (GHG)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Institutions, values, beliefs and behaviour
Countries involved: United Kingdom,United Kingdom
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-01-01
End date: 2013-12-31
Duration (months): 60.0
Total project cost (EUR): 2349246.0
EU funding (EUR): 2349246.0
Participants: 2
Project status: CLOSED

Globalisation has changed health conditions worldwide, affecting the lives and livelihoods of hundreds of millions. While historically many health issues have readily crossed borders (e.g. Black Plague), the intensification and extensification of contemporary globalisation processes has required new forms of governance to address changed global health needs. How do we collectively protect and promote health in an increasingly globalised world? This challenge has opened up a contested space known as global health governance (GHG) where the stakes are high but where different perspectives compete and contradict. It is also a poorly understood space. This programme aims to significantly advance our understanding of this space and the competition within it. It builds on a small body of existing literature to which the two applicants have already made important contributions, but represents a step change in two important respects. First, existing analyses have been limited to single approaches or perspectives. This programme represents the first sustained attempt at a comparative analysis incorporating a variety of perspectives and health issues. Given that the space is contested, it is only through such an analysis that we can significantly advance our understanding of GHG. Such an approach would represent a major advance on the current state of the art. Second, analysis to date has focused on disease and especially infectious disease. The applicants have been at the forefront of critiquing this approach as overly narrow (for example McInnes and Lee, 2006). This programme addresses infectious disease as one of the key issues in global health governance, but also incorporates non-communicable disease and non-disease based health issues in an explicit attempt to broaden the analysis to cover more fully the space occupied by global health governance.

Keywords: global health governance,world health organization,international public health,politics of infectious and non-communicable diseases,international relations,international health regulations.
Architectural Freeform Structures from Single-Curved Panels (ARC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria,France,Austria
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-03-01
End date: 2013-02-28
Duration (months): 48.0
Total project cost (EUR): 1128459.0
EU funding (EUR): 1128459.0
Participants: 3
Project status: CLOSED

Complex freeform structures are one of the most striking trends in contemporary architecture. So far, design and manufacturing of such structures are based on digital technologies which have been developed for other industries (automotive, naval, aerospace industry). Architecture differs from these traditional target industries of CAD/CAM technology in many ways including aesthetics, statics, structural aspects, scale and manufacturing technologies. Manufacturing architectural freeform structures requires the segmentation into panels, which may be either flat, single-curved or double curved. In the present proposal, we investigate the problem of building architectural freeform structures from single-curved panels. From the mathematical perspective, this leads to the new semi-discrete surface representations, which constitute a link between smooth and discrete surfaces and can be studied with methods from differential geometry and computational mathematics. To meet the practical requirements, solid knowledge and large experience in architectural design and engineering is essential. Three partners joined to meet the challenges in this field: (1) TUW, an academic institution with deep fundamental knowledge in applied geometry and geometric computing, (2) Evolute, a high-tech research start-up specializing in geometric computing for architecture and manufacturing and (3) RFR, an established engineering office with world wide experience, specialized in non-conventional lightweight structures and with relevant experience in freeform design.

Keywords: computational mathematics,computer-aided design,applied geometry,differential geometry,architectural design
Indigeneity in the Contemporary World: Performance, Politics and Belonging (IPCWPPB)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: ERC Advanced Grant Interdisciplinary Panel
Countries involved: United Kingdom
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-04-01
End date: 2014-11-30
Duration (months): 68.0
Total project cost (EUR): 2363323.0
EU funding (EUR): 2363323.0
Participants: 1
Project status: CLOSED

This project explores how indigeneity is expressed and understood in our complex, globalising world. It asks why indigeneity has accumulated immense symbolic and ideological capital in Western societies when indigenous cultures are among the most disenfranchised in modern times, often still struggling for social justice after centuries of colonisation. Specifically, I ask what indigeneity has come to mean in particular places and at key moments, and what kind of cultural, political, ethical and aesthetic issues are negotiated within its canvass. To address these questions, I will examine performance as a vital mode of cultural representation and a dynamic social practice. Performance is interpreted broadly to include not only the performing arts (theatre, film and dance) but also mixed-media work, site-based heritage projects, applied theatre in health education, Olympic pageantry, festival enactments, political protest and cultural displays within tourism ventures. The recent, rapid development of indigenous performance globally, its enthusiastic reception in national and international contexts, and its local significance and value will be studied in depth. I am especially interested in how evolving concepts of indigeneity may contribute to broader understanding of heritage, belonging, social cohesion and mobility in multicultural societies and how cultural values, knowledges and practices are transmitted, through performance, across place and time. The research will be thoroughly interdisciplinary, engaging with current scholarship in history, postcolonial studies, cultural geography, anthropology, environmental studies and performance theory. While the projected fieldwork focuses on regions settled during the great era of European expansionism, notably Australia, the Pacific Islands, the Americas and South Africa, the project is also centrally concerned with the transnational circulation of indigeneity as a highly marketable commodity, particularly in Europe.

Keywords: interdisciplinary studies,indigenous cultures,globalisation,postcolonial theory,heritage,environmental justice
Evaluation and management of collective long-term risks (LONG-TERM RISKS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Individuals, institutions and markets
Countries involved: France
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-01-01
End date: 2014-12-31
Duration (months): 72.0
Total project cost (EUR): 1400000.0
EU funding (EUR): 1400000.0
Participants: 1
Project status: CLOSED

The aim of this research proposal is to provide a unified framework to evaluate and to manage collective long-term risks, with applications to environmental risks (climate change, genetically modified organisms, nuclear wastes, non-renewable resources, biodiversity, &). What should we be willing to give up to reduce these risks? What is the best timing for action? How should the risk evaluation be adapted to the absence of objective probabilities, the conflicts between and biases in individual beliefs, the heterogeneity of individual preferences towards these risks, the ability to predict future impacts, the limited capability to share risk efficiently, or the changing expectations about long-term economic growth and about the scarcity of environmental resources? To examine these questions, we will combine various approaches from modern decision theory, the theory of finance, environmental economics and behavioural economics. This research is also aimed at helping collective decision making by improving the standard tools of benefit-cost analysis for the specificities of long-term risks: discounting of far distant effects, risk premium for fat tails, ambiguity premium, aggregation rules for heterogeneous beliefs and preferences, and option values. We will translate general concepts as sustainable development , corporate social responsibility and precautionary principle into efficient guidelines for collective decision making.

Keywords: environmental economics,long-term risk,decision theory under uncertainty
IAPP on novel genetic and phenotypic markers of Parkinson's disease and Essential Tremor (MARKMD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Iceland
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-03-01
End date: 2013-02-28
Duration (months): 48.0
Total project cost (EUR): 1173548.0
EU funding (EUR): 1173548.0
Participants: 2
Project status: CLOSED

Copy number variations (CNV) are ubiquitously found throughout in the human genome. Their role in monogenic as well as multifactorial disorders as potential disease modifier is more and more stressed (Abecasis et al., 2007). In order to investigate the role of CNV in Parkinson’s disease (PD) and Essential Tremor (ET), two frequent neurological diseases, MARKMD brings together the unique expertises of deCODE genetics (Iceland) and University of Tübingen (Germany). On the one hand, deCODE genetics will contribute and transfer its unique genetic, epidemiologic and biostatistical expertise. The University of Tübingen, on the other hand, will contribute and transfer neuroimaging and clinical expertise in regard to PD and ET. Co-operation and transfer of knowledge is dedicated to the establishment of new tools for the detection of disease associated CNV and clinical markers in patients as well as healthy at-risk groups. Thus, we anticipate to come up with new neuroimaging/clinical and genetic markers relevant to the etiology and progression of PD and ET. Transfer of knowledge will be implemented through secondments, recruitments, and meetings. There will be a structured exchange of principle investigators from both partners at project milestones facilitating the training of newly recruited team members. All recruited project members will have workpackages at either partner which allows to disseminate project outcomes easily.

Keywords: health sciences,brain research,neurology
Personalized health monitoring (PHM)- Interdisciplinary research to analyse the relationship between ethics, law and psychosocial as well as medical sciences (PHM-ETHICS)

Framework: FP7 — Capacities
Programme: Science in Society
Destination: A more dynamic governance of the science and society relationship
Action type: Collaborative project
Countries involved: Germany,Sweden,United Kingdom,Germany,France,Netherlands,Belgium
Call:  (FP7-SCIENCE-IN-SOCIETY-2008-1, 2008)
Start date: 2009-07-01
End date: 2012-06-30
Duration (months): 36.0
Total project cost (EUR): 1267351.0
EU funding (EUR): 998113.0
Participants: 7
Project status: CLOSED

The aim of PHM-Ethics is to scientifically analyse the dependencies between ethics, law and psychosocial sciences in a dynamic part of IT development, i.e. personalized health monitoring (PHM), from a European perspective. First, the development of PHM will be reviewed to identify core steps that delineate major changes from an ethical, legal and psychosocial point of view. A taxonomy will be elaborated based on research evidence in each of the disciplines, and interrelations will be documented into a map. The project will be situated at the development phase of new technologies, however also at the early application phase. As a major step, the implementation of ethical constraints contained in EU/ international instruments into the national laws or regulations will be analysed, and gaps will be identified. At the end of project phase 1, the taxonomy will be validated in an international expert workshop. The aims of the second project phase are to develop and test an interdisciplinary methodology that allows assessing PHM technologies regarding their ethical, legal and psychosocial consequences. The interdisciplinary methodology will be pilot-tested on a qualitative basis and validated in selected personal health monitoring applications at different stages of the taxonomy. The objective of the study is to gain scientific input from the patient and provider point of view. Results of an empirical study will be analysed in terms of differences between development stages and socio-demographic factors. The third project phase is related to the exploitation of knowledge and research products, with regard to policy-making and implementation of technological innovations. PHM-Ethics will provide a tool that allows studying future PHM applications on different taxonomic levels concerning their consequences to serve both internal and external dissemination purposes within the 7th framework, also projecting the methodology to other technological field (e.g. the security area).

Keywords: information technology and monitoring,personal health monitoring,ethical assessment,interdisciplinary research
A Multi-agent Approach to Digital Business Ecosystems (ECOBUSINESS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Spain
Call:  (FP7-PEOPLE-IAPP-2008, 2008)
Start date: 2009-09-01
End date: 2012-08-31
Duration (months): 36.0
Total project cost (EUR): 404877.0
EU funding (EUR): 404877.0
Participants: 2
Project status: CLOSED

The purpose of EcoBusiness is, on one hand, to increase the productivity and the position in the market of MicroArt (and other similar SMEs) by applying cutting edge techniques and methodologies coming from academia, either from the field of management and economics, through the MSE-UEDIN, as well as from the field of artificial intelligence and information systems, through the collaboration with CISA-UEDIN, while giving the opportunity to the university (UEDIN) to test the products of its research in a real scenario while acquiring all the expertise from a real SMEs market network. On the other hand, this programme pretends to facilitate the acquisition of knowledge by the experts at MicroArt on recent research fields such as interaction-centered knowledge sharing, information ecosystems, and digital business ecosystems, while offering the researchers at UEDIN the necessary knowledge to know how to test and evaluate their research findings and results in real-like scenarios.

Keywords: business,sme,innovation,efficiency,collaborative work environments,competitiveness,digital ecosystems,multi agents,knowledge sharing.