Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Autoxidation of Anthropogenic Volatile Organic Compounds (AVOC) as a Source of Urban Air Pollution (ADAPT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Finland
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-02-01
End date: 2026-01-31
Duration (months): 60.0
Total project cost (EUR): 2689147.0
EU funding (EUR): 2689147.0
Participants: 1
Project status: SIGNED

Previous efforts to raise living standards have been based on relentlessly increasing combustion, causing environmental destruction at all scales. In addition to climate-warming CO2, fossil fuel combustion also produces a large number of organic compounds and particulate matter, which deteriorate air quality. The atmosphere is cleansed from such pollutants by gas-phase oxidation reactions, which are invariably mediated by peroxy radicals (RO2). Oxidation transforms initially volatile and water-insoluble hydrocarbons into water-soluble forms (ultimately CO2), enabling scavenging by liquid droplets. A minor but crucially important alternative oxidation pathway leads to oxidative molecular growth, and formation of atmospheric aerosols. Aerosols impart a huge influence on the atmosphere, from local air quality issues to global climate forcing, yet their formation mechanisms and structures of organic aerosol precursors remains elusive. In a paradigm change, RO2 was recently found to undergo autoxidation, enabling rapid aerosol precursor formation even at sub-second time-scales – in stark contrast to the long processing times (days - weeks) previously assumed to be necessary. We have shown how abundant biogenic hydrocarbons (BVOC) autoxidize, but due to key structural differences, the same pathways are not available for anthropogenic hydrocarbons (AVOC), and thus they were not expected to autoxidize. My preliminary experiments reveal that AVOCs do autoxidize, but the mechanism enabling this remain unknown. Crucially, the co-reactants shown to inhibit BVOC seem to enforce AVOC autoxidation – potentially explaining the recent mysterious discovery of new-particle formation in polluted megacities. In ADAPT, I will use a combination of novel mass spectrometric detection methods fortified by theoretical calculations, to solve the mechanism of AVOC autoxidation. This will directly assist both air quality management, and the design of cleaner fuels and engines.

Keywords: atmospheric pressure chemical ionization,atmospheric and combustion chemistry,gas phase organic oxidation reaction mechanisms,aerosol precursor formation,rapid free radical rearrangements
Search for Higgs bosons decaying to charm quarks (HIGCC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-09-01
End date: 2023-08-31
Duration (months): 72.0
Total project cost (EUR): 1973875.0
EU funding (EUR): 1973875.0
Participants: 1
Project status: SIGNED

In the standard model of particle physics (SM), the Higgs boson explains the existence of mass of the elementary particles. However, the model suffers from severe weaknesses: radiative corrections drive the theoretical mass of the Higgs boson to extremely high, unnatural values, while the observed mass is rather low (the famous hierarchy problem). Unknown mechanisms of physics beyond the standard model (BSM) must exist to avoid this unnatural situation. Such BSM mechanisms modify the predicted properties and decay patterns of the Higgs boson. The experimental collaborations at the LHC are measuring these decay patterns as precisely as possible. The decay of the Higgs boson into bottom quarks is dominant with a predicted decay fraction of 57%. Neither this nor the subdominant decay into charm quarks of 2.9% have ever been observed. The small decay fraction into charm quarks makes it susceptible to BSM modifications, if they exist. A measurement of this charm decay fraction would either unravel new physics that has been sought for more than 60 years, or constrain BSM scenarios to enhance the understanding of the fundamental theory of matter. However, the decay of the Higgs boson into charm quarks has been considered to be experimentally inaccessible at the LHC, because of the difficulties to distinguish charm quarks from other quarks. In this proposal I will show how to overcome these experimental obstacles with new methods for the detection of charm quarks in the CMS detector. The new methods will be based on decay vertex reconstruction algorithms that make use of modern pattern recognition concepts. In combination with new techniques for data analysis and interpretation, this will facilitate the first observation of the Higgs to charm decay, and the measurement of its branching fraction, if it is anomalously enhanced through BSM contributions. With this strategy the first indication for physics beyond the standard model may be found.

Keywords: cms experiment,large hadron collider,cern,higgs boson
Organ on Chip in Development (ORCHID)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Coordination and support actions
Countries involved: Spain,Germany,Belgium,France,Netherlands,Netherlands,Netherlands
Call: FET-Open Coordination and Support Actions (H2020-FETOPEN-3-2017, 2017)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 520472.5
EU funding (EUR): 520472.5
Participants: 7
Project status: CLOSED

Organ-on-chip technology will revolutionize the healthcare domain by offering new and ground breaking solutions to different industries and especially for regenerative medicine and medication. ORgan-on-Chip In Development (ORCHID) will create a roadmap for organ-on-chip technology and the framework to build a network of relevant stakeholders. ORCHID will achieve this through 5 objectives: (i) evaluation of the technology (state of the art and unmet needs), (ii) identification of ethical issues, establishing standards and identifying measures for regulatory implementation, (iii) analysis of economic and societal impact, training and education, (iv) developing a roadmap which will guide the required R&D efforts and (v) raising awareness and building the ecosystem for organ-on-chip technology through a digital reference platform . ORCHID will have a broad impact: it will facilitate drug development, contribute significantly to reducing animal experiments and help in developing personalized medicine. ORCHID will achieve these goals by providing a framework to the main stakeholders, bringing together key players and raising awareness on organ-on-chip technology throughout Europe. The digital platform will gather all information on existing and new initiatives in the field. In this way ORCHID as a whole will secure and reinforce Europe’s leadership on organ-on-chip. The consortium is composed of the main contributors to the field who are all very experienced and who will strongly collaborate with each other. Leiden University Medical Centrum (LUMC) will lead the consortium, the Institute for human Organ and Disease model (hDMT) will focus on the strategy and the roadmap, Fraunhofer IGB on impact assessment, CEA Leti on eco-system development and the digital platform, IMEC on the ethical aspects, regulation and standardization and the University of Zaragoza will lead dissemination. ORCHID will install an Advisory Board composed of complementary specialists in the field.

Keywords: organ on chip,network,digital platform,roadmap,regulation,etchics,standardization,regenerative medicine,medication
Unravelling the molecular mechanisms of monocot embryogenesis (EmBd)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 165598.8
EU funding (EUR): 165598.8
Participants: 1
Project status: CLOSED

One key question in developmental biology is how a single-celled zygote develops into a functional organism consisting of different organs and tissues during embryogenesis. Knowledge about embryogenesis in plants has been tremendously advanced in the last two decades after adopting the dicot plant Arabidopsis thaliana as a model organism. Auxin and WUSCHEL_RELATED_HOMEOBOX transcription factors have been shown to play essential roles in patterning such as apical-basal axis formation and meristems initiation. However, how the embryo of monocot plants develops is still mostly unknown, although monocot grasses encompass the world’s most important food, feed and bioenergy crops. Compared to dicot embryo development, monocot embryogenesis has its own unique features, such as unpredictable cell division, monocotyledon and a root originated from embryo center. While much has been discovered by studying Arabidopsis embryogenesis, it is currently not clear if these concepts can be directly transposed to monocots. Brachypodium distachyon has recently emerged as a new monocot model species because of its clear advantages over crop model species. Thus, I propose to systematically study monocot embryogenesis using Brachypodium distachyon in the Weijers lab. By combining live imaging, modelling of key genetic interactions, transcriptome profiling, and genetics, I will try to understand how the embryo develops. I aim to reveal molecular similarities and divergence in tissue patterning between monocot and dicot embryogenesis by studying the function of auxin and WOX genes in Brachypodium, as well as discover the molecular networks that regulate the unique aspects of monocot embryogenesis. This will increase our knowledge on early patterning events critical to set up the initial body plan in monocots and the biological diversity of plant early development. In addition, this action will greatly assist me to reach scientific maturity and independence.

Keywords: monocot embryogenesis,brachypodium distachyon,live imaging,modelling,transcriptome profiling,genetics,auxin,wuschel related homeobox transcription factors
The multisensory dimension of memory, from single neuron to neural network. A multiscale electrophysiological approach to reveal the mechanism of face-voice association for person identity recognition (MIMe)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-01
End date: 2020-04-30
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

Long-term memory is intrinsically multisensory: after learning, the various sensory inputs related to an event are associated into an abstract representation. Multimodal representations present clear behavioural benefits for adaptation, like facilitating recognition. Nonetheless, while multisensory integration and memory are profoundly nested brain processes, little is known about the neural basis of their reciprocal influence. Is remembering multimodal, by nature? Do multisensory representations influence sensory processes? In the present project, I will elucidate these queries from a neurophysiological standpoint using a unique multiscale approach in human subjects: from the single cell to the brain network level. Specifically, I will combine the use of a micro-meso electrode prototype with surface EEG to characterize underlying neuronal oscillatory mechanisms and macroscopic aftermaths. Lastly, to direct our research I will utilize a key medium for social interaction: face-voice association, core of person identification. This multidisciplinary and innovative project will be carried out at the CerCo laboratory (CNRS, France), where a pioneer platform for intracranial recording inhuman has recently been developed. I will transfer to the host institution my expertise in advanced LFP analysis and precise three-dimensional electrode localization. Conversely, I will learn single-cell techniques, the state-of-the-art from experts in human memory and participate in oral communication trainings. Furthermore, my project action will adhere to a knowledge dissemination plan, from the scientific community for results communication to broader public audiences in order to illustrate research assets to the community. Ultimately, this research program will be a stepping-stone toward my independent line of research and as such will definitively contribute to my career advancement at the host laboratory.

Keywords: multisensory integration,memory,human intra cranial recording,electroencephalography eeg,local field potential lfp,single cell recording
A Gendered History of Emotions in Renaissance and Counter-Reformation Italy (WomenThinkingLove)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2024-10-14
Duration (months): 34.0
Total project cost (EUR): 252573.12
EU funding (EUR): 252573.12
Participants: 2
Project status: SIGNED

WomenThinkingLove will provide the first History of Emotions of Renaissance and Counter-Reformation Italy, with regard to the system love/marriage/adultery, from a gender perspective. As Renaissance and Counter-Reformation Italy are still under-investigated from the perspective of the History of Emotions, the project will start an urgent research, beginning with an emotional field, love, that was central in the cultural debates of the time. Within the theoretical framework of the History of Emotions, it will combine literary studies, history of ideas and women's studies. Based on the comparison between the love theories of the time and a wide range of literary and non-literary texts containing women's voices and cognitive interactions between men and women (taken from printed and archival sources), the research will challenge the idea of women as passive recipients of men's philosophical elaborations about love, and the stereotypical idea of Counter-Reformation as an un-nuanced era of repression for women's agency. It will contribute to the ongoing re-thinking of the traditional historical periodization, highlighting the continuity in the ideas and practices of love between Renaissance and Counter-Reformation. The research is divided in three phases: a secondment at Florence University and State Archive, during which the fellow will be trained in the new methodologies of History of Emotions and archive research; an outgoing phase at NYU, under the supervision of V. Cox, a world-leading expert of Renaissance and Counter-Reformation women's writing; a return phase at Oslo University, with the guide of U. Falkeid, a prominent scholar whose approach is based exactly on the combination of literary studies and intellectual history, focused on early modern women's thinking. Beyond its scholarly value, the new narrative of women's agency provided by the research will hopefully help to counter the sexist attitude still persisting in contemporary society.

Keywords: history of emotions,gendered emotions,renaissance and counter reformation italy,women s writing,love theories and practices,love correspondences,marriage and adultery
Inhabitable Bridges in a Privacy Perspective (IBridge)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-08-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 328968.0
EU funding (EUR): 328968.0
Participants: 1
Project status: SIGNED

The privatization of public land is a global challenge, as public land is for public services. This long-lasting challenge of public policy and consequently of the architecture of public space reminds us the architectural type of inhabitable bridge as traditional walled-off paths and gated communities in Early Modern (EM) Europe, which mediated between public and private territories, as a city on itself, a dualism of connectedness and separation. I shall, therefore, conduct a case study of the inhabitable bridges (IBs), which specifically will reveal the emergence of public privacy (PP) beyond the privatization of public paths in IBs, called "Inhabitable Bridges in a Privacy Perspective" (IBridge), focusing on EM Europe since the public privacy fostered. Utilizing the two important examples in terms of location and size, the demolished Old London Bridge and the Pont de Notre-Dame in Paris, I will analyze how public policy developed these bridges in terms of public and private ownership and what the architectural and social effects of this development were. The remaining challenges in the public realm require a focus on their historical background in EM architecture and policy to find concerns and values. An analysis of the interconnectedness of the IBs' architecture and PP values will help us understand the impact and relations between political agents, spatial organization, PP attitudes in EM Europe. In this way, IBridge recalls the challenges and values of the EM European public realm that cultivated distinct ways of providing PP that strongly linked to both the political and cultural sphere, drawing on earlier lessons for public comfort in urban scenes. The Royal Danish Academy, Schools of Architecture, Design and Conservation (KADK), Center for Privacy Studies (PRIVACY) at Copenhagen University, and Institute for the History and Theory of Architecture (GTA) at ETH Zürich serve as an excellent host to IBridge, as their focus is on architectural and privacy studies of EM European cases led by an interdisciplinary board and scholars.

Keywords: privacy,public realm,inhabitable bridge,early modern europe,architecture,urbanism,old london,bridge,pont de notre dame,interdisciplinary,gender
communicating ERC projects through cOMICS (ERCcOMICS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: ERC other
Action type: Coordination and support actions
Countries involved: France
Call: ERC Support for novel ways to highlight the work funded by the ERC and reach out a wider public. (ERC-2014-SUPPORT-1, 2014)
Start date: 2015-11-01
End date: 2019-10-31
Duration (months): 48.0
Total project cost (EUR): 791146.0
EU funding (EUR): 791146.0
Participants: 3
Project status: CLOSED

ERCcOMICS is a creative and ambitious project which proposes to exploit the power of visual storytelling through webcomics to promote and explain the achievements of ERC funded projects and the benefits of the ERC funding scheme for technological and scientific development, as well as for society as a whole. ERComics will: - produce 16 webcomics about carefully selected ERC funded, drawn by different comic artists; - organise graphic facilitated TED-style lectures jointly held by ERC grantees and comic artists; - organise at least two exhibitions about the project itself; - carry out all needed actions of dissemination to maximise the impact of the project.

Keywords: support actions,communication,dissemination,comics,webcomics,communicating through comics,storytelling,graphic facilitation videos
Scalable European Powertrain Technology Platform for Cost-Efficient Electric Vehicles to Connect Europe (1000kmPLUS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Innovation actions
Partnership: EGVI (cPPP)
Countries involved: Germany,Germany,Austria,Germany,Germany,Germany,Germany,France,France,Czechia
Call: Integrated, brand-independent architectures, components and systems for next generation electrified vehicles optimised for the infrastructure (H2020-LC-GV-2018, 2018)
Start date: 2019-01-01
End date: 2023-06-30
Duration (months): 54.0
Total project cost (EUR): 6736651.38
EU funding (EUR): 5405286.26
Participants: 12
Project status: SIGNED

The need for common, scalable and brand-independent technology platforms for the key elements of EV, like the inverter-motor-transmission/gearbox (powertrain) and the battery, is evident. The project 1000kmPLUS will ensure the superiority of European automotive key technologies in terms of performance, scalability and costs for the 2nd and 3rd generation of EV. The EV powertrain and battery technologies must now start to mature, in order to fulfil existential human mobility needs in terms of affordability and usability: this is the key to enter the early mass market. It assumes ramp-up of series production and affordability by economies of scale. 1000kmPLUS will provide key arguments regarding the usability of the 2nd generation of EV to the Early Majority customers. Further, it will speed up the development and the ramp-up of series production of the 3rd EV generation. To obtain breakthroughs in terms of energy efficiency, driving range, charging and costs, the 1000kmPLUS project develops a Scalable European Powertrain Technology Platform (SEPtop@SiC), which will define automotive powertrains for EV as commodities. It will use 1200 V SiC-MOSFETs to enable a 400 V/800 V cross-compatible inverter-motor-gearbox combo, scalable as a function of the required performance. Furthermore, ultra-fast charging up to 350 kW for everyday use will be demonstrated in an EV providing an initial driving range of 500 km based on its battery energy capacity. The 1000kmPLUS project will enable, demonstrate and set up European mass production capabilities of EV key components (inverter, motor, transmission, SiC-MOSFET power modules, battery cells) by Europe´s leading automotive companies. Further, it will build ECS value chains with focus on quality, safety, efficiency and costs. The 1000kmPLUS project will build up a Mercedes-Benz EQ vehicle to demonstrate the project achievements by performing 3 challenges, representing real use cases for business as well as private travellers.

Keywords: scalable,platform,fast charging,semiconductors,components,energy management,battery,connectivity,electric vehicle