Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Bio-inspired laser functionalization of complex 3D industrial surfaces (BILASURF)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Made in Europe (co-programmed)
Countries involved: Spain,Germany,Austria,France,Lithuania
Call: Products with complex functional surfaces (Made in Europe Partnership) (RIA) (HORIZON-CL4-2022-TWIN-TRANSITION-01, 2022)
Start date: 2023-01-01
End date: 2026-05-31
Duration (months): 41.0
Total project cost (EUR): 5601669.0
EU funding (EUR): 5601668.75
Participants: 10
Project status: SIGNED

Surface functionalisation is present in a wide range of sectors, improving the performance of multiple components and systems in many applications. However, when considering the application of such functionalisation in complex industrial parts, several challenges must be faced. The difficulty of reaching all surfaces of complex 3D parts is significative, especially in those with considerable size and weight. At the same time, uncertainty about the regulatory compliance of functionalised parts in some sectors makes a straightforward integration of this process more difficult. As a result, this limits the potential of some companies in terms of opening up new markets or attaining a competitive edge. Additionally, the creation of functional surfaces has traditionally relied on processes such as chemical reactions and/or the complete coating of the native surfaces (e.g. aerofoils). Due to their very nature, these processes generate unwanted by-products thereby leaving a significant environmental footprint, which go against the “do no significant harm” principle of The European Green Deal. In order to avoid these setbacks, a new functionalising process for complex 3D shaped parts in which the environmental footprint is reduced and where new guidelines are generated to complement the manufacturing standards of target sectors, could be a game changer. BILASURF aims at developing and integrating a process for high-rate laser functionalization of complex 3D surfaces using tailored designed bio inspired riblets to reduce friction and improve the environmental footprint of industrial parts, assuring a high throughput with the help of inline monitoring capabilities. This solution can provide European industry with a key tool to use a more efficient and environmentally friendly manufacturing process.

Keywords: green flexibleanddigitized laser processes highly rotating parts friction reduction energy usage reduction flexibleandversatile functionalization acoustic monitoring enabled positioning control system
The pursuit of non-invasive treatment for intracranial aneurysms to PRevent aneurYSMal subarachnoid hemorrhage (Treat-PRYSM)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-04-01
End date: 2026-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 2
Project status: SIGNED

Rupture of intracranial aneurysms (IA) results in aneurysmal subarachnoid hemorrhage (aSAH), an often fatal type of stroke. Invasive IA treatment to prevent aSAH is a high-risk procedure, limiting its use and leaving most IA patients untreated. Thus, there is an urgent need for non-invasive drugs preventing aSAH, but these are lacking as our understanding of the causal disease pathways is poor. The considerable female predominance in IA and aSAH suggests the existence of sex-specific regulation of these pathways. In the ERC PRYSM StG we identified candidate drugs lisinopril, amlodipine, tamsulosin, simvastatin and metformin associated with a reduced risk of aSAH. These targets have an inhibitory effect on the Transforming Growth Factor-β (TGF-β) pathway, a potent inducer of Endothelial-to-Mesenchymal transition (EndMT), a driver of vascular disease. The Treat-PRYSM team’s main aim is to transition the research from the ERC PRYSM StG into innovation by performing the following activities: 1) Confirm and validate our 5 candidate drugs—lisinopril, amlodipine, tamsulosin, simvastatin and metformin—as effective drugs in reducing aSAH incidence, by employing the principle of drug repurposing and triangulating evidence from epidemiological and genetic data. 2) Find genetic evidence that the EndMT and TGF-β pathways are involved in IA pathogenesis, thereby identifying these pathways as potential therapeutic targets for the candidate drugs, using a large-scale genomics approach. 3) Determine whether the mode of action of the candidate drugs and EndMT/TGF-β pathways is influenced by sex. 4) Evaluate the opportunities for a clinical trial of the most promising candidate drug to assess its ability to inhibit growth of IAs, serving as a surrogate marker for rupture. This approach will ultimately provide a non-invasive, cost-effective drug to prevent aSAH in patients with unruptured IAs and will significantly enhance our understanding of the disease's causal pathways.
Artificial Intelligence Experimentation Facility For the Energy seCTor (AI-EFFECT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Ireland,Portugal,Denmark,Netherlands,France,Germany,Norway,Austria,Italy,Spain
Call: AI Testing and Experimentation Facility (TEF) for the energy sector – bringing technology to the market (HORIZON-CL5-2024-D3-01, 2024)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 5656875.0
EU funding (EUR): 5299661.25
Participants: 20
Project status: SIGNED

AI-EFFECT will establish a European Testing Experimentation Facility (TEF) for developing, testing, and validating AI applications in the energy sector. It will be distributed across nodes, virtually connecting existing European facilities. The solution includes a digital platform leveraging European building blocks for interoperability, flexibility, and scalability. AI-EFFECT aims to be a central hub for testing energy sector AI algorithms, fostering collaboration across utilities, industry, academia, and regulatory authorities. Resilience is ensured through a decentralized design, aligning with the EU Energy Data Spaces framework. The project involves developing 4 use cases/nodes addressing key energy challenges, focusing on district heating, transmission congestion management, DERs integration, and energy communities. The framework involves utilities proposing challenges, vendors developing algorithms, and researchers contributing solutions. Each use case has evaluation criteria, baselines, and benchmarks. AI certification procedures, including interpretability and verification, will be implemented, and the evaluation process will be automated. Benchmarks and certifications are publicly available, encouraging open-source contributions. The project breaks sector barriers, leveraging existing infrastructures and technologies for cross-sectoral collaboration. The platform enforces policies for data quality, integrity, and privacy, promoting controlled data sharing and collaboration. Secure APIs ensure controlled interactions, including risk and security assessments. The consortium explores certification, standardization, and quality requirements in line with the EU AI Act. Governance and business models for the enduring AI-EFFECT will be examined, considering the EU AI Act. The consortium aims to make AI-EFFECT a sustained business beyond initial funding, seeking input from members, other TEFs, and regulatory authorities for the preferred model.

Keywords: tef,artificial intelligence,energy sector,certification,distributed architecture,digital platform,european collaboration network,decentralized design,use cases,data security,eu ai act
MariTech Talent Programme (MariTech Talent)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: A human-centred and ethical development of digital and industrial technologies
Action type: Coordination and support actions
Countries involved: Bulgaria,Greece,Cyprus
Call: Green and digital skills and training needs for a just transition (CSA) (HORIZON-CL4-2023-HUMAN-01, 2023)
Start date: 2023-12-01
End date: 2025-11-30
Duration (months): 24.0
Total project cost (EUR): 614687.5
EU funding (EUR): 499375.0
Participants: 10
Project status: SIGNED

The MariTech Talent will develop a twin transition INTRApreneurship skills development programme, bringing maritime industry professionals and innovative enterprises with concrete digital solutions together in a two-way learning experience. The programme will provide: - Necessary twin skills for the maritime workforce - Support to deep tech solutions providers developing key technologies for unlocking the twin transition in the maritime industry Thе MariTech Talent programme will apply a challenge-based INTRApreneurship model which will nurture learning by working on the most pressing needs identified by the ports and maritime companies themselves. Teams consisting of current workers and deep tech startups, scaleups and SMEs will work together to apply concrete solutions, undergoing the necessary training on the way. On the one hand the programme will secure the required skill set for the maritime workforce related to the green and digital transition. They will acquire operational knowledge in key digital domains enablers of the twin transition in the maritime industry such as machine learning and data analysis for predictive maintenance, energy management systems, system integration, automation, remote operation, cybersecurity and e-navigation through direct collaboration with deep tech solution providers. On the other, it will provide valuable insights and feedback on the relevance and effectiveness of the applied digital solutions. As a final result, maritime companies and ports will gain in-depth insights into the benefits digital solutions can bring to their operations, while at the same time their employees will become skilled and confident in their use.

Keywords: twin skills green and digital transition upskilling maritime industry deep tech talents
Circadian system ageing in cancer: from tumourigenesis to treatment (CircTu-Age)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-06-01
End date: 2031-05-31
Duration (months): 60.0
Total project cost (EUR): 1499300.0
EU funding (EUR): 1499300.0
Participants: 1
Project status: SIGNED

Age is cancer's primary risk factor and a significant determinant of how the resulting disease presents and progresses. Yet the specific contribution of ageing’s diverse hallmarks to this phenomenon is poorly defined. Circadian rhythms are a conserved adaptation that enables organisms to anticipate daily environmental cycles and thus mitigate their harmful effects on the body. However, in recent years, a decay of homeostatic cellular, tissue and systemic circadian rhythms has emerged as a hallmark of mammalian ageing. Concurrently, in the context of cancer, circadian inputs from the host are known to drive daily rhythms in tumour microenvironment composition, metastasis seeding and treatment response, whilst disruption of physiological circadian rhythms is itself an established tumour promoter. When considered together, this raises the intriguing possibility that ageing of the circadian system may reshape cancer circadian biology in a manner pertinent to its prevention or treatment. In particular, three key questions emerge: 1) Does ageing of the body and its circadian rhythm system change the tumourigenic potency of circadian rhythm disruption? 2) Are the circadian rhythms of an established tumour altered by ageing of the host and its circadian system? 3) If cancer circadian biology is rewired by ageing, can we identify where this change originates from? In CircTu-Age, we will combine cutting-edge models of ageing and cancer with targeted circadian rhythm disruption and circadian-omics to define how ageing impinges upon the circadian biology of cancer. This timely project will reveal the as-yet-uncharacterised interaction between an emerging hallmark of ageing, circadian rhythm decay, and the most common of age-related diseases, cancer. The knowledge generated by CircTu-Age will provide a roadmap for identifying interventions that diminish cancer risk later in life, and contribute to refining and expanding the burgeoning field of cancer chronotherapy.

Keywords: ageing,cancer,circadian rhythms,inter tissue communication,colorectal cancer,melanoma,gemm,premature ageing
Passing down Indigenous memory. Mapping innovation crossovers and social transformation in an outermost region of Europe (400K Memories)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-01
End date: 2026-09-30
Duration (months): 36.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

Following the eruption of a major social crisis in an “Outermost region of European Union” (ORs), French Guiana, which gave rise to the “French Guiana political agreement” in 2017, the French government committed to a full retrocession process of 400,000 hectares of land to Indigenous communities (Native Americans). 400,000 ha of land, it’s also 400,000 different memories of the land, and certainly even more. This project aims to strengthen and make visible Indigenous representations in the overall institutional process of land retrocession. This participatory project implements the creation of an original and unpublished double corpus, previously unseen in French Guiana. By associating an artistic and a narrative approach, “sensibility mapping” allows for the visualisation of the intimate aspects of Indigenous stories. Over the last decade its potential to integrate qualitative data such as emotions and sensations into maps has caught the attention of a few geographers. Our first goal is to develop a first series of “sensibility maps” with Indigenous storytellers through an innovative mapping process designed to put the stories about the land memory into full light (O1). Our second goal is to represent the creative process at work when drawing the first series of maps, using the very same sensibility mapping method and drawing a second series of maps (O2). Our last and most ambitious goal is to create a hybrid open-data archive designed to foster a new use of the research material through a cross-mapping innovation between geolocated and sensibility maps (O3). The recent research in history of cartography has highlighted the importance of documenting the mapping process itself. But as of today no visualisation technique has been developed to represent that process. From a methodological perspective this project is thus timely, as it is from a cultural perspective since it will engage a mapping experiment at a crucial political moment in French Guiana history.

Keywords: autochthony,french guiana,outermost region of eu,land retrocession process,collaborative cartography,mapping innovation,life stories,cultural memory,sensibility mapping,social transformation
Unveiling the Shadows: Illuminating Late Pleistocene Human-Carnivore Interactions in Europe (SHADOWS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1499813.0
EU funding (EUR): 1499813.0
Participants: 1
Project status: SIGNED

Caves played a vital role for Pleistocene human and carnivore populations, serving as shelters, scavenging sites, and feeding grounds. They remain the primary context preserving archeological and faunal remains in Europe. Carnivores competed with Pleistocene humans for resources and significantly contributed to cave bone accumulations and modification. Notably, evidence of carnivore behaviors largely derives from anthropogenic contexts, studied through an anthropo-centric lens. However, carnivore remains are often invisible in the archeological register, making it difficult to study them and draw precise conclusions about the level of interaction with humans and their extinction dates. Here, I hypothesize that many species of Pleistocene carnivores are present in Europe for much longer than what the fossil record indicates, that their presence can be assessed by revising the sediments and bones of archeological sites, and that the lasting populations show signs of genetic collapse linked to population contraction. Therefore, I propose to study Pleistocene carnivores in Europe, focusing on Iberia, during and after the Late Glacial Maximum, a period marked by human population decline and climatic refugia. The rich and complex archeological setting in the region will be used to identify, date, and delineate lasting carnivore populations. This information will improve the understanding of human-carnivore interactions. To do this, I have designed an innovative approach, uniting cutting-edge methods like high spatiotemporal precision sampling for sediment DNA and paleoproteomics, which combined with traditional zooarchaeological techniques overcomes the limitations of fossil availability. The research has the potential to: a) Improve the understanding and nature of the cooccurrence between Pleistocene humans and carnivores, and b) characterize the biological process of extinction helping us improve the conservation of current critically endangered fauna.

Keywords: carnivores,paleolithic,sedadna,genomics,zooarcheology
GÉANT Horizon Europe GN5-IC1 (GN5-IC1)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Networks and infrastructures
Action type: Research and Innovation actions
Countries involved: Netherlands,Serbia,Portugal,Italy,Greece,Ireland,Denmark,Spain,United Kingdom
Call: SGA for investments on International connectivity and collaboration (HORIZON-INFRA-2021-NET-01-SGA-2, 2021)
Start date: 2022-12-01
End date: 2026-05-31
Duration (months): 42.0
Total project cost (EUR): 18565826.25
EU funding (EUR): 15000000.0
Participants: 12
Project status: SIGNED

Under the new 72-month GN5 Framework Partnership Agreement in Horizon Europe (GN5-FPA), this proposal responds to Horizon Europe Call HORIZON-INFRA-2021-NET-01-SGA-2 (Work Programme ’21-22 Other Actions: 2. SGA for investments on International connectivity and collaboration), received 1 February 2022. GN5-IC1 sets out a new plan and implementation for the first phase of a new intercontinental connectivity investment programme, meeting the huge growth in network capacity demands and leading the network through a paradigm shift in the digital science and computational infrastructures in the next 10 to 15 years. It builds on the successful and relevant experience in planning and procuring and introducing into operation direct intercontinental links, such as BELLA S1, as well as a number of other existing bilateral and reciprocal arrangements for operational links negotiated with other intercontinental partners. This project will help ensure sufficient capacity is put in place through procurements and implementations of links during the project term or through setting a roadmap for future investments beyond this timeframe. The GÉANT Consortium has a long established and successful track record in securing long-term intercontinental network connectivity, interconnecting with an increasing number of gateways in the network, in co-ordination with global peers. Applying proven skills and expertise, GÉANT is well placed to maximise the value of the links to be procured, with innovative contracts and to secure reciprocal global peering contributions to increase the impact of the resources available in GN5-IC1.

Keywords: connectivity,networks,research networking,multi domain networking,communication networks,secure,trust,innovation,media,digital sovereignty,computer sciences,e infrastructure