Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Ultracold Molecules in Optical Trap Arrays (UMOTA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2020-06-14
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Classical computers quickly hit the brick wall when asked to model the behavior of interacting quantum systems. For example, calculating the time evolution of a quantum system consisting of only 40 interacting spin-½ particles is believed to be fundamentally impossible on a classical computer. Fortunately, the direct investigation of such systems is coming into the reach of today’s most powerful quantum simulators. In this approach, a controllable quantum system is used to model the behavior of other less accessible systems of interest. I plan to make a versatile, reconfigurable array of strongly-polar Calcium Monofluoride (CaF) molecules, and investigate its utility as a scalable quantum simulator. These ultracold molecules have long lifetimes and interact over large distances via their strong electric and magnetic dipole moments. They can thus be used to investigate a wide range of many-body quantum phenomena and are promising candidates for the simulation of lattice spin models, which are omnipresent in condensed matter physics. In the Center for Cold Matter at Imperial College London, CaF has recently been magneto-optically trapped and laser-cooled to a record-breaking temperature of 50µK. As an MSCA fellow I will build upon these results. I will develop techniques to confine a single CaF molecule in an optical tweezer trap, then assemble a controllable array of molecules using multiple tweezer traps, and finally investigate the entangling dipole-dipole interaction between two neighboring molecules by coherent microwave control. These experiments will take place in a complexity regime where results can still be numerically simulated and will thus serve as benchmark tests of a future scalable quantum simulator.

Keywords: ultracold molecules,polar molecules,quantum simulation,optical tweezers,optical dipole traps
Emergence of high-mass stars in complex fiber systems (EMERGE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Austria,Germany
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-09-01
End date: 2025-08-31
Duration (months): 60.0
Total project cost (EUR): 1497805.0
EU funding (EUR): 1497805.0
Participants: 2
Project status: SIGNED

High-mass stars drive the physical and chemical evolution of the Universe. However, the origin of these massive objects is largely controversial. Three key questions remain under debate: a) Which physical processes determine the formation of high-mass stars? b) How do these stars get their large masses? c) Do high-mass stars form in a similar way to their low-mass counterparts? Galactic surveys link the origin of high-mass stars to the initial properties of their gas embryos. Using the Atacama Large Millimeter Array (ALMA), I recently proved the existence of a new and fundamental filamentary organization of the gas within the Orion Nebula, the nearest high-mass star-forming region. After leading this key discovery, I propose to investigate the formation of high-mass stars as an emergent process in complex systems. In this novel scenario massive stars are created naturally by the internal interactions within networks of filaments of increasing density. To fully characterize this ground-breaking approach, this project will carry out the first systematic study of (1) the substructure, (2) internal interactions, and (3) dynamical evolution of these filamentary systems across the Milky Way. EMERGE will survey a homogeneous ALMA sample of >30 massive filamentary networks, the largest of its kind, extracted from the first intensive exploitation of its public archive. These observational results will be tested against state-of-the-art simulations using a new generation of analysis tools. The ultimate goal of this project is to statistically quantify how unique multi-scale phenomena generated in these filamentary systems, such as collisions, mergers, and self-gravity, determine the initial conditions for the formation of high-mass stars. This ERC-StG project will solve a current challenging dichotomy in star-formation theory. In combination with low-mass studies, EMERGE will provide a major step towards a comprehensive model of star-formation under one filamentary paradigm.

Keywords: star formation,filaments,fibers,clusters,high mass,low mass,cores,molecular lines,observations,alma
A NOVEL NON-INVASIVE SOLUTION FOR CONTINUOUS BLOOD PRESSURE MONITORING (ICA-100)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Blood pressure follow-up is essential in managing hemodynamically unstable patients at Intensive Care Units (ICU). Traditionally, mercury sphygmomanometers have been used for this purpose, and are regarded as the gold standard for Blood Pressure measurement. Despite the relative simplicity of the technique, sphygmomanometers have obvious limitations regarding accuracy and tracking capability, especially crucial for hospital patients. In the most critical patients the invasive arterial line catheter must be used, which however poses serious risks for severe complications. Over the past decades, several attempts have been undertaken to develop an effective, accurate and reliable solutions to continuously monitor blood pressure in a non-invasive way. Hitherto, none of the solutions under development have achieved a massive market deployment. Major obstacles for the implementation of state-of-the-art solutions are related to their limited performance, resulting in poor accuracy in hypo/hyper tension episodes, influence of patient movements on the system response, and need for periodic and frequent recalibrations. ICARIA has developed a solution for blood pressure monitoring (ICA-100) based on a novel operating principle that allows obtaining an accurate diastolic and systolic Blood Pressure read-out. The ICA-100 has already been validated in healthy volunteers (TRL5). The technology is protected by two international patents, granting ICARIA freedom-to-operate. In the frame of this Phase 1 Project we aim to further develop our marketing strategy and financial plan. Besides, we aim to assess thoroughly the relevant regulatory and legal framework for the Project. After completing this feasibility study, we plan to develop and commercialise a certified device for Continuous Non-Invasive Blood Pressure monitoring. Having a positive impact in 655m hospital patients and a potential favourable effect on 1.3b hypertensive individuals, from which only 1 in 5 is under control.

Keywords: blood pressure monitoring
PracticAl and Effective tools to moNitor and Assess CommErciAl drivers’ fitness to drive (PANACEA)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Austria,Spain,Italy,Austria,Belgium,Sweden,Greece,Greece,Sweden,Sweden,Greece,Sweden,Netherlands,United Kingdom
Call: Improving road safety by effectively monitoring working patterns and overall fitness of drivers (H2020-MG-2020-TwoStages, 2020)
Start date: 2021-05-01
End date: 2024-04-30
Duration (months): 36.0
Total project cost (EUR): 3498466.25
EU funding (EUR): 3498466.25
Participants: 18
Project status: SIGNED

PANACEA has 17 partners from 8 countries coming from multidisciplinary fields. The project will design, develop and test a holistic driving ability assessment system for commercial drivers to be used pre-driving, during driving and at the roadside, paired with cloud-based countermeasure and coaching solutions. In order to achieve this, PANACEA will create driver-oriented, health-based, touchless, and Use Case (UC) driven health monitoring and assessment solutions capable of detecting alcohol, licit (barbituric), illicit (methadone replacement) drugs, fatigue, stress, and cognitive load. Those drivers detected as unfit by the assessment/monitoring technology will receive personalised, targeted support from the cloud-based countermeasure and coaching system. Commercial Health Toolkits (CHTs), combining assessment/monitoring techniques with countermeasure solutions, will be tailored to fit the specific needs of each UC. The CHTs aim to become an ecosystem of support and knowledge for drivers and operators alike, available before/after/during shifts as well as on site and roadside. The sensitivity, specificity, robustness, ease-of-use, satisfaction and acceptance of these CHTs will be evaluated with over 90 AV shuttle, e-truck, coach and taxi drivers and courier service riders, operators and stakeholders, across 3 UC-driven Pilots (Greece, Spain and Sweden), considering gender specificities. A 4th UC focus on the transferability of the improved knowledge and technologies to other transport modes (i.e. aviation, maritime and rail). The primary outcome of PANACEA is the creation of new assessment technologies and countermeasure strategies which come together as a new fitness to drive paradigm applicable in commercial vehicle operations with vehicles at various automation levels. Finally, with the support of the Advisory Board, policy and legislative recommendations and updates of existing standards for health provision for commercial transportations will be provided.

Keywords: fitness to drive,safety,health,working conditions
Replication of innovative concepts for peri-urban, rural or inner-city mobility (RECIPROCITY)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Coordination and support actions
Countries involved: Austria,Spain,Germany,Belgium,Türkiye,Finland,Hungary,France,France,Czechia
Call: Cities as climate-resilient, connected multimodal nodes for smart and clean mobility: new approaches towards demonstrating and testing innovative solutions (H2020-MG-2020-SingleStage-INEA, 2020)
Start date: 2021-02-01
End date: 2023-09-30
Duration (months): 32.0
Total project cost (EUR): 1498831.25
EU funding (EUR): 1498831.25
Participants: 13
Project status: SIGNED

Mobility is changing. Urbanization, climate change and digitalisation challenge how people and goods move from A to B. To cope with these challenges and to meet global climate targets, urban and inter-urban areas need to become well-connected multimodal and multi-usage nodes for smart and clean mobility. Despite the success of early pilot projects, there is still a gap when it comes to transferring innovations to different contexts, cities or regions. One the one hand, living labs, testbeds, demonstration pilots do not always reflect urban reality as they were designed specifically for testing purposes. On the other hand, these solutions were implemented based on the requirements and needs of one particular city, district or area. City planners and project developers, therefore, face the question how the results of mobility pilot projects can be used in order to implement smart city strategies and community initiatives more efficiently, faster and on a larger geographic scale? RECIPROCITY will provide answers. The project’s goal is to initiate and support replication projects in at least 20 cities and municipalities varying in size, location, degree of urbanization and mobility demand. They will be equipped with the tools, knowledge and contacts to accelerate the process of replicating innovative mobility solutions. The consortium will organize coordination and support actions along the process from idea to implementation to nurture replication. Using a four-staged replication framework, the project will help cities and municipalities to: • IDENTIFY the right innovative mobility solutions together with all relevant mobility stakeholders and citizens; • LEARN about requirements, processes and skills needed to put these innovative mobility solutions into action; • ACCELERATE the implementation of these solutions through guidance and matchmaking for business and finance; • SHARE and build upon lessons learned and best practices to enable fast replication on a wid

Keywords: accelerate mobility solutions
DEVELOPMENT OF SMART AND FLEXIBLE FREIGHT WAGONS AND FACILITIES FOR IMPROVED TRANSPORT OF GRANULAR MULTIMATERIALS. (HERMES) (HERMES)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Spain,Spain,Sweden,Sweden,France,Denmark
Call: Smart Rail Services (H2020-MG-2014_TwoStages, 2014)
Start date: 2015-05-01
End date: 2018-04-30
Duration (months): 36.0
Total project cost (EUR): 6707335.0
EU funding (EUR): 6705209.0
Participants: 13
Project status: CLOSED

Rail freight transportation is a system service where a multitude of players, participants and systems providers bear a high degree of responsibility for its attractiveness and performance. It shows high efficiency as transportation means, in terms of land use and energy consumption and low greenhouse gas emissions. However rail’s market share of freight transportation and its economic efficiency continues to be limited. Aimed at overcoming such uncertainty, this project addresses one of the most important key resources for further developing rail freight transportation: the optimization of the performance of the rail freight wagon. The continuous pressure on environmental issues and energy efficient transport is forcing the rail transportation sector to enhance the rail logistics services and to incorporate innovative solutions to improve load capacity to keep the “best-in-class” position and, therefore, acquiring a much privileged position beyond alternative terrestrial transport source, as truck transportation. Thus, aimed at optimizing rail freight transportation, the main objective of this project is to holistically address the aspects that may improve freight wagon performance: enhanced logistics, improved multimodal operative, higher load capacity, optimized filling/emptying time and flexibility to transport multi-products. This project aims to achieve such optimization by combining industrial expertise on the freight wagon design and construction, advanced materials for lightweight construction and logistics with the research capabilities to incorporate innovation solutions and optimize material performance.

Keywords: lightweight,granular materials,corrosion coatings,high strength steels,composites
Fundamentals of ASymmeTric Organo-CATalysis (FASTO-CAT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-04-01
End date: 2022-09-30
Duration (months): 66.0
Total project cost (EUR): 1892500.0
EU funding (EUR): 1892500.0
Participants: 1
Project status: CLOSED

For most biologically relevant molecules their chirality is decisive for their function. Within the last two decades asymmetric organo-catalysis has emerged as an environmental benign, metal-free alternative for conventional asymmetric transition metal catalysis. The organo-catalysts, which employ catalyst-substrate interaction motifs commonly found for enzymes, yield unprecedented enantiomeric excesses. Despite the success of these organo-chemical routes, remarkably little is known about the molecular details of the interaction between the catalyst and the substrate. Consequently, there is virtually no rationale method to optimize reaction conditions particularly as related to structure-function relationships. Also the exact nature of the intermediates that induce chirality has remained elusive. The aim of this proposal is to experimentally quantify the formation of reaction intermediates and the nature of intermediate induced chirality that lie at the heart of asymmetric control. This will be achieved by using a combination of advanced spectroscopic techniques. With advanced vibrational spectroscopies (ultrafast two-color and two-dimensional infrared spectroscopy), dielectric spectroscopy, and NMR spectroscopy together with quantum chemical calculations we will quantify structure-dependent interactions: binding geometry, strength of attraction, lifetime of binding, reaction intermediates, and the role of steric repulsion, probed on all timescales relevant to catalytic processes ranging from femtoseconds to seconds. Correlation of such information with the enantiomeric excess obtained in catalytic processes will allow isolating the essential ingredients for stereocontrol. Such molecular-level insights will provide fundamental parameters for optimization of reaction conditions and will initiate the transition from a trial and error approach towards a rational design of new catalytic processes.

Keywords: asymmetric catalysis,organo catalysis,stereocontrol,hydrogen bonding,ion pairing,dielectric,spectroscopy,two dimensional infrared spectroscopy,ultrafast spectroscopy,terahertz
Miniaturized System for Screening of Primary Cells based on Droplet Microarray (Droplet Microarray)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2020-02-01
End date: 2023-12-31
Duration (months): 47.0
Total project cost (EUR): 2499750.0
EU funding (EUR): 1749825.0
Participants: 1
Project status: SIGNED

Current cell screening systems based on microtiter plates are mainly used to perform drug discovery experiments. However, performing a larger number of therapeutic tests on patient derived (primary) cells is yet impossible due to the high consumption of reagents and cells when using microplates. In the clinical context, personalized drug screenings for optimal medical treatment are not possible due to the scarcity of precious primary cells. In pre-clinical drug discovery, the extremely high cost of primary cells limits the innovation potential as researchers hardly have access to screening models which are relevant for human physiology. The possibility to use scarce cell types like primary cells or stem cells therefore is the future of basic life science research, drug discovery (replacing animal models) as well as personalized medicine applications (individual precision therapies) and will have significant impact for a healthy society. Further miniaturization of current assays would inevitably allow the wide use of scarce cell types and at the same time reduce costs, increase throughput, and increase biological relevance of screening results. DMA allows researchers and clinicians to perform meaningful experiments with primary cells and circulating tumor cells – alternative technologies hardly work with low cell numbers. EC funding Phase 2 will allow Aquarray to mass produce its offer – the DMA Cartridge and also the disruptive Cell Screening System that integrates the DMA Cartridge with a nanoliter dispenser, an incubator and a read-out apparatus. Aquarray’s disruptive business model will employ a B2B direct sales of the DMA Slides and the Screening System, and at the same time sales can be maximized through partnerships with companies selling liquid nano-dispensers such as Dispendix and Labcyte. We are expected to generate €167M revenues by 2025 capturing 9.37% of the market.

Keywords: droplet microarray,cell screening,drug discovery,personalised medicine,primary cells,stem cells
The transnational mobility of cheap print: British chapbooks in Italy, 1800-1850 (CHAP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Ireland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2017-08-31
Duration (months): 24.0
Total project cost (EUR): 175866.0
EU funding (EUR): 175866.0
Participants: 1
Project status: CLOSED

This action proposes mobility for an Italian researcher living in Britain to work in Ireland on a transnational historico-literary project. Her research focuses on the cross-cultural transfer of cheap print between Britain and Italy in the first half of the nineteenth century. The project advances existing knowledge of popular publishing and reading in two ways. Firstly, it contributes to the European historiography of cheap publications by extending the investigation of their production, distribution and reception to the Italian context. Secondly, and most importantly, it provides a concrete idea of the cross-cultural nature of cheap literature by exploring the mechanisms which regulate its migration from one linguistic and cultural realm to another. The transnational trajectory of cheap print is investigated with a focus on translation and on its potential to establish fruitful negotiations between the literary and cultural repertoires of the source and the target context. The project examines a corpus of chapbooks translated from English into Italian published between 1800 and 1850. The Italian chapbooks and their sources are analysed using an interdisciplinary approach which integrates theories of textuality, the history of the book and of reading, and translation studies. The comparative approach followed in my study will significantly enhance our understanding of popular literature and of the processes which led to the formation of a shared European heritage of popular culture. The multidisciplinary research environment at NUIG provides the ideal conditions for the researcher to develop this project and the skills necessary for her future academic career. The collaboration of Dr Niall Ó Ciosáin and the training that she will undertake in the history of the book will be particularly important to integrate her familiarity with translation and the eighteenth- and nineteenth-century Italian cultural context with new knowledge of popular publishing and reading.

Keywords: cross cultural mobility,cheap print,popular culture,translation,literary heritage