Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Molecular Logic Circuits (MOLOC)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Future and emerging technologies
Action type: Collaborative project
Countries involved: Belgium,Israel,Germany,Germany,Germany,Netherlands,Germany
Call:  (FP7-ICT-2007-1, 2007)
Start date: 2008-02-01
End date: 2011-01-31
Duration (months): 42.0
Total project cost (EUR): 2669186.0
EU funding (EUR): 2040000.0
Participants: 7
Project status: CLOSED

MOLOC – Molecular Logic Circuits seeks to design and provide demonstration of principle, feasibility and significant advantages of logic circuits where the basic element is a single molecule (or assemblies of atoms or molecules) acting in itself as a logic circuit. The functionalities provided by this new post-Boolean approach differ in essential ways from using a molecule as a switch. The approach depends on molecules (or nanostructures, etc) having internal degrees of freedom and multiple (quasi)stationary states by virtue of their confined size. We therefore make an advantage of the nanosize which is imposed by the cardinal technological need to reduce the size of the circuit in order to implement complex logic functions at the hardware level and thereby add new functionalities. Exploratory work has shown that it is possible to address the states of a single molecule either electrically (or electrochemically) or optically and also that it is possible to concatenate the logic operation of two molecules. The partners to MOLOC are cognizant that to go beyond the projected limits of CMOS technology will likely be most productive if it be a surface based approach. All the same, foundational work in the gas or liquid phase is also discussed. MOLOC proposes parallel computing rather than the more familiar sequential model, it proposes to take advantage of inherent internal degrees of freedom of molecules and their dynamics in order to implement finite state machines, machines that can store information to be used later in the computation and to consider circuits where the logic goes beyond Boolean , meaning that variables are not restricted to be either true (=1) or false (=0). Towards its objectives MOLOC proposes to gather a team of European experts in the different and complementary areas of foundational research. The experimental teams can be characterized by the methods used to address (or probe) the molecule. There is also one theoretical work package.

Keywords: molecular circuits,non-boolean logic,parallel computing,finite state machines,electric & optic i/o
Multimodal Immersive Motion Rehabilitation with Interactive Cognitive Systems (MIMICS)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Cognitive systems, interaction, robotics
Action type: Collaborative project
Countries involved: Switzerland,Slovenia,Spain,Germany
Call:  (FP7-ICT-2007-1, 2007)
Start date: 2008-01-01
End date: 2010-12-31
Duration (months): 36.0
Total project cost (EUR): 2227502.0
EU funding (EUR): 1600000.0
Participants: 6
Project status: CLOSED

The main hypothesis of this project is that movement training for neurorehabilitation can be substantially improved through immersive and multimodal sensory feedback. The approach is real-time acquisition of behavioural and physiological data from patients and the use of this to adaptively and dynamically change the displays of an immersive virtual reality system, with the goal of maximising patient motivation. This will result in complex systems that are natural, user-friendly and easy to use. In this project two exemplary systems will be developed for robot-assisted rehabilitation of upper and lower extremities. The systems will be able to record multi-sensory data (motion, forces, voice, muscle activity, heart rate, skin conductance etc.) and process this data in real-time to infer the intention of the patient and the overall psycho-physiological state. The computed information will be used to drive the therapy robots in combination with immersive virtual reality systems including 3D graphics and 3D sound. Several individually adjustable scenarios will be set up and the patient will be immersed into the corresponding virtual environments. Experimental tests on humans will evaluate to which such systems can increase the motivation of the patients and, thus, the therapeutic outcome of the training. New basic insights will be obtained about presence and motivation in humans. Furthermore, MIMICS technology will enter clinical routine so that large patient populations (e.g. stroke, spinal cord injury) can benefit. Motor rehabilitation will become more efficient and may reduce costs of the European health care systems. A multi-national network is required to better compensate regional differences and increase international acceptance. The MIMICS consortium is characterised by an ideal balance of engineers, computer scientists, physicians and one industrial partner, who are all word-leaders in their respective fields.

Keywords: rehabilitation,robotics,virtual reality,immersion,presence,intention,motivation
An integrated study on three novel regulatory hubs in megakaryocytes and platelets, discovered as risk genes for myocardial infarction by a genome-wide association and platelet systems biology study (NETSIM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Netherlands,Germany,Germany,United Kingdom,Germany,Ireland,United Kingdom
Call:  (FP7-PEOPLE-2007-1-1-ITN, 2007)
Start date: 2008-09-01
End date: 2012-08-31
Duration (months): 48.0
Total project cost (EUR): 2851384.0
EU funding (EUR): 2851384.0
Participants: 10
Project status: CLOSED

The overarching objective of the ITN is to offer an intercalated study environment for young and talented researchers in the field of coronary artery disease (CAD) research. 12 PhD fellows operating in a unique training environment will work as a multi-disciplinary team to perform research spanning the full spectrum from basic to translational to bring novel inventions to the bedside. The fellows will be mentored by world-leading experts to shape a new generation of European leaders in biomedical science and overcome current fragmentation in Europe. The research is at the forefront of biomedical science because of the UK genome-wide association study in 2000 myocardial infarction (MI) patients and our EU-FP6 integrated projects Bloodomics and Cardiogenics. We will exploit our knowledge about the genetic architecture of MI to investigate the hypothesis whether sequence variation of genes encoding network hubs poses a greater risk for network destabilisation compared to genes encoding regular nodes. Focusing on three hub genes we postulate that genetic/bio-markers associated with hubs can be integrated in algorithms for MI/CAD risk prediction. Success will critically depend on new developments in computing, machine learning, pattern recognition and advanced data mining and statistical analysis. To have a free development path from basic discovery to health care improvement young scientists must be taught to cross the classic barriers between academic disciplines. We offer a timely and necessary alternative to Europe’s classic PhD programmes by providing a seamlessly integrated multi-disciplinary environment in an academic-private sector partnership free of boundaries. Our aim is a targeted strategy for prevention and treatment based on a better understanding of the genetic and molecular mechanism of disease. This will deliver major advances in public health and patient care, which can only be achieved if a new scientific cadre is developed.

Keywords: risk genes,hubs,biomarkers,pattern recognition,myocardial infarction,computational biology
Exploring and understanding adverse drug reactions by integrative mining of clinical records and biomedical knowledge (EU-ADR)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Towards sustainable and personalised healthcare
Action type: Collaborative project
Countries involved: Netherlands,Spain,Portugal,Italy,France,United Kingdom,Denmark,Sweden,United Kingdom,Italy,Spain,Netherlands
Call:  (FP7-ICT-2007-1, 2007)
Start date: 2008-02-01
End date: 2012-01-31
Duration (months): 48.0
Total project cost (EUR): 5871496.0
EU funding (EUR): 4500000.0
Participants: 15
Project status: CLOSED

Serious adverse effects resulting from the treatment with thalidomide prompted modern drug legislation more than 40 years ago. Post-marketing spontaneous reporting systems for suspected adverse drug reactions (ADRs) have been a cornerstone to detect safety signals in pharmacovigilance. It has become evident that adverse effects of drugs may be detected too late, when millions of persons have already been exposed. In this project, an alternative approach for the detection of ADR signals will be developed. Rather than relying on the physician’s capability and willingness to recognize and report suspected ADRs, the system will systematically calculate the occurrence of disease (potentially ADRs) during specific drug use based on data available in electronic patient records. In this project, electronic health records (EHRs) of over 30 million patients from several European countries will be available. In an environment where rapid signal detection is feasible, rapid signal assessment is equally important. To rapidly assess signals, a number of resources will be used to substantiate the signals: causal reasoning based on information in the EHRs, semantic mining of the biomedical literature, and computational analysis of biological and chemical information (drugs, targets, anti-targets, SNPs, pathways, etc.). The overall objective of this project is the design, development and validation of a computerized system that exploits data from electronic healthcare records and biomedical databases for the early detection of adverse drug reactions. The EU-ADR system will generate signals using data and text mining, epidemiological and other computational techniques, and subsequently substantiate these signals in the light of current knowledge of biological mechanisms and in silico prediction capabilities. The system should be able to detect signals better and faster than spontaneous reporting systems and should allow for identification of subpopulations at higher risk for ADRs.

Keywords: electronic patient records,patient safety,adverse drug event,pharmacovigilance,data mining
Functional liquid Crystalline dendrimers: Synthesis of New Materials, Resource for New Applications (DENDREAMERS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,France,United Kingdom,Greece,Portugal,Germany,Lithuania,Spain,Sweden
Call:  (FP7-PEOPLE-2007-1-1-ITN, 2007)
Start date: 2008-10-01
End date: 2012-09-30
Duration (months): 48.0
Total project cost (EUR): 4219110.0
EU funding (EUR): 4219110.0
Participants: 9
Project status: CLOSED

Dendrimers are new materials obtained with a highly controlled molecular structure in several space orientations. Liquid Crystals (LC) Dendrimers are a part of them that incorporate directional properties to these materials. If we append active molecules into these engineered molecules, we can obtain multifunctional anisotropic molecules that open the possibility of achieving a wide variety of physical properties and new applications. Among the numerous possibilities to be explored within this field, we have chosen two fundamental lines, which are Biomedicine and Advanced Molecular Materials. Training of multidisciplinary personnel in this field of research will contribute to concentrate the knowledge spread in different countries and to accelerate the development within Europe by means of industrial collaboration. This collaboration will provide an up-to-date list of requirements for better planning the research lines that ensure a rapid evolution of the existing ones in Europe, all of which are oriented to the synthesis of compounds easily transferable to industrial use. The aim is to reduce the existing gap between academically developed new materials and their industrial application. Multidisciplinary training will include modelling of new materials, chemical synthesis and controlled chemical orientation, structural functional studies, physical characterization of structural properties, biological modelling, molecular activity analyses, technology oriented samples and product escalation towards industry processes. These training aspects will go parallel to a research career, complementary formation and cooperation key-events.

Keywords: dendrimers,liquid crystals,biomedicine,molecular materials science
Around an inspiring virtual learning world in eighty days (80DAYS)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Digital libraries and content
Action type: Collaborative project
Countries involved: Austria,Switzerland,Ireland,United Kingdom,Germany,Germany,Italy
Call:  (FP7-ICT-2007-1, 2007)
Start date: 2008-04-01
End date: 2010-09-30
Duration (months): 30.0
Total project cost (EUR): 4207281.0
EU funding (EUR): 3263839.0
Participants: 9
Project status: CLOSED

Recreational computer games are overwhelmingly popular. Hence, there is no doubt that educational games, which combine effective learning with fun and pleasure, are a desirable vision. Still, educational games, which can compete with their non-educational counterparts in terms of narrative and gaming quality, have not yet entered the market – especially those for children who are used to the quality of computer games. The main reason is the difficulty in merging both game and educational environments. To cross today’s horizon of educational games, a scientifically sound and valid methodological and technological foundation is required. Grounding on this mission, 80Days is a RTD project concerned with theories, methodologies, and technologies for game-based learning. To accomplish a significant step towards successful and effective educational games, 80Days is addressing the following two main objectives: First, integrating models of adaptive personalised learning with those of adaptive interactive storytelling, and second, merging virtual game environments with existing learning resources, thus reducing development costs and time. These fusions will result in an adaptive and responsive system, enabling the understanding of active learning processes within a virtual learning environment, adapting to individual needs and abilities, and therefore fully exploiting the learners’ capabilities. The quality of this approach will be assured by evaluation activities based on theoretically and empirically sound methods. 80Days entails the smooth integration of interdisciplinary work (learning science, storytelling, game and didactic design, game development, and human-computer interaction). 80Days delivers an innovative and advanced methodological and technological framework for effectively developing successful educational games to be demonstrated by a geography game prototype realising gaming/learning scenarios inspired by Jules Verne’s “Around the world in eighty days”.

Keywords: immersive digital educational games,inspiring learning environments,adaptive and narrative learning environments,micro and macro-adaptive interventions,probabilistic competence assessment
Combined Organic LED Technology for Large Area Transparent and low cost lighting Applications (COMBOLED)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: Germany,France,Germany,Spain,France,Italy,Germany
Call:  (FP7-ICT-2007-1, 2007)
Start date: 2008-01-01
End date: 2011-02-28
Duration (months): 38.0
Total project cost (EUR): 7198323.0
EU funding (EUR): 4187163.0
Participants: 7
Project status: CLOSED

Solid state lighting is a fascinating research field which brought up the revolutionary breakthrough technology of inorganic LEDs during the last decade. These are now migrating into the general lighting field. A new development route is already identified with organic light emitting devices in large area and nm-thin architectures being complementary to inorganic point sources. These organic light-emitting devices (OLEDs) for lighting purposes are expected to have broad market opportunities due to their out-standing properties. They can act as nearly two dimensional diffuse light sources as well as for signage applications. They have the potential to offer transparency and flexibility paving the way for completely new applications. As efficiencies above 50 lm/W are targeted these novel light sources have also the potential to decrease the global energy consumption. Similar efficiencies and lifetime compared to existing solutions is a prerequisite for new lighting technologies. A staircase improvement from today’s level towards 50 lm/W and 5000 h lifetime of large area tiles can be expected which will be sufficient for first niche applications soon. However, an effective market introduction of OLEDs for lighting and signage would become the lighting revolution in the future as soon as: • the cost structure is competitive • a unique selling point like transparency is explored. So one of the major “road block” that is still ahead are manufacturing costs: If no breakthroughs in terms of new low-cost processes are made, OLED technology will not enter the market in large volume, even if the performance would allow competing. The second issue to be addressed in CombOLED takes care about the uniqueness of OLED for lighting: Besides the advanced form factor of OLED lighting panels further unique selling attributes must be develop. Within CombOLED the emphasis is on creating transparent devices which will open a completely new perspectives for lighting and signage.

Keywords: organic leds,lighting,signage,low-cost manufacturing,transparent devices,vacuum and wet-chemical processing
Enhancing Literacy Development in European Languages (ELDEL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,Czechia,Slovakia,France,France,Spain
Call:  (FP7-PEOPLE-2007-1-1-ITN, 2007)
Start date: 2008-09-01
End date: 2012-08-31
Duration (months): 48.0
Total project cost (EUR): 3752311.0
EU funding (EUR): 3752311.0
Participants: 7
Project status: CLOSED

The scientific aims of the ELDEL project are: 1) to produce a model elucidating the relationships among psychological (psycholinguistic, cognitive) and environmental (orthographic, linguistic, educational/instructional, cultural) factors determining the development of literacy skills in European languages, and 2) to uncover the key components of an effective, culture-appropriate intervention program for the prevention and remediation of literacy problems in the languages under study. The research program comprises a number of overlapping cross-linguistic studies that will reveal the language-specific and language-general factors affecting literacy development. This multidisciplinary network includes partners with expertise in developmental, educational, and clinical psychology, experimental psycholinguistics, speech and language therapy, and an industrial partner specialising in the creation of software for the assessment and training of literacy skills. Each partner will also contribute to the network’s training aims, to provide training in generic as well as in state-of-the-art domain-specific research skills. Participants will offer training in one or more of the following specialist areas: (a) specific literacy skills (e.g., phonological skills, spelling, reading comprehension), (b) typical vs. clinical populations (e.g., children with developmental disorders, dyslexia), (c) research methodology (e.g., longitudinal, intervention, experimental psycholinguistic, naturalistic), and (d) use and development of measurement tools (computer-generated, eye tracking, cross-linguistic tests). Additional training in relevant skills will be provided by visiting researchers during workshops and short courses. The projects are conceived to promote mobility within the network and allow young researchers to benefit from the training most relevant to them. This ITN will equip Early Stage and Experienced Researchers for successful careers in cutting-edge literacy research.

Keywords: social sciences,literacy,cross-linguistic,spelling,reading,dyslexia,language disorders,prediction,intervention,phonology,morphology,orthography,alphabetic,development
Autonomous Production of Images based on Distributed Sensing (APIDIS)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Digital libraries and content
Action type: Collaborative project
Countries involved: Belgium,United Kingdom,Switzerland,Spain,Belgium
Call:  (FP7-ICT-2007-1, 2007)
Start date: 2008-01-01
End date: 2010-12-31
Duration (months): 36.0
Total project cost (EUR): 2615541.0
EU funding (EUR): 1925000.0
Participants: 6
Project status: CLOSED

Democratic and personalized production of multimedia content is one of the most exciting challenges that content providers will have to face in the near future. In this proposal, we plan to address this challenge by proposing a framework to automate the collection and distribution of digital content. As a federating objective, APIDIS targets cost-effective autonomous production, so as to make the creation of audiovisual reports profitable, even in case of small- or medium-size audience. First, APIDIS will investigate the automatic extraction of intelligent content from networks of multi-modal sensors. Intelligence refers here to the identification of salient segments within the audiovisual content, using distributed scene analysis algorithms. Second, our project will exploit that knowledge to automate the production of video content for controlled scenarios, e.g. most notably sports events or surveillance. Finally, the APIDIS consortium will consider personalized and potentially interactive content summarization mechanisms, to address heterogeneous user needs and access conditions. The potential applications of the integrated technology and methodologies that will be developed within APIDIS are numerous, ranging from personalized access to digital media related to local sport events through a web portal or a mobile hand-set; cost-effective and fully automated production of content dedicated to small-audience, e.g. souvenirs DVD, university lectures, etc; but also automated summarization for video surveillance.

Keywords: video,automatic creation,scene analysis,omnivision,planing and scheduling