Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
MOdular Eco WAterbus ABLE TO BE DIVIDED INTO TWO IDENTICAL INDIPENDENT HYBRID UNITS ALLOWING OPERATING FLEXIBILITY IN TRANSPORTATION (MOEWA)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Italy
Call: Small business innovation research for Transport (H2020-SMEINST-1-2015, 2015)
Start date: 2015-12-01
End date: 2016-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Econboard is a startup company which introduces a design based on 2 owned patents, able to modify the nautical transport in internal and coastal waterways. A design was perfected of a hybrid catamaran boat thought for transport of persons and things, able to be easily divided in two independent units which can operate on different routes. When they are assembled, the two units are a single boat of double load capacity that can be called modular. A propulsion system, based on azimuth electric thrusters in line allows the boat assembled, but also to the two elementary units, to play their mission with increased safety because they can rotate on site and do maneuvers impossible for conventional units, greatly increasing the safety of navigation above all in the tight spaces of internal waterways. The concepts of modularity, increased maneuverability and a new propulsion system, full electric or hybrid, greatly increase the building standards of the internal waterways boats according to 2006/87/EC that sets high standards in terms of environmental protection and safety. The modularity also allows advantages for all the stakeholders: for the yard, because it meets always different market demands in terms of transport capacity, with the same product, thus simplifying the design and reducing the resources for building; for the owner because in this way he can manage with greater flexibility his business complying in a better way the seasonality of the service and facing without interrupting service the machine downtime. For the community because of its intrinsic eco-sustainability. A preliminary analysis of the market shows excellent prospects for the business because Econboard proved that the cost of the two elementary units is comparable than the cost of one conventional unit of double capacity. This activity requires a careful analysis of the market looking for the correct position of the product in the market and the correct company organization to face it.

Keywords: boat,waterbus,catamaran,azimuth,thrusters,ecological,electrical,transportation,modular,hybrid,low noise,flexibility,modularity
Technologies for Ocean Sensing (TechOceanS)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Cross-cutting marine and maritime research
Action type: Innovation actions
Countries involved: Ireland,Spain,Germany,Germany,Italy,Cyprus,Greece,France,United Kingdom,United Kingdom
Call: The Future of Seas and Oceans Flagship Initiative (H2020-BG-2020-1, 2020)
Start date: 2020-10-01
End date: 2024-09-30
Duration (months): 48.0
Total project cost (EUR): 9252881.76
EU funding (EUR): 8975662.17
Participants: 14
Project status: SIGNED

TechOceanS will produce and demonstrate in multiple underwater vehicles, 9 new technologies enabling a step change in ocean biology, chemistry and plastic observation. The technologies include 5 sensors, two imaging systems, a sampler and a new image processing method using Artificial Intelligence (AI) that enables data compression and transmission of information about key variables from the remote ocean. All the systems are robust and submersible to >2000 m and collectively measure at least 63% (12/19) of priority Biogeochemical and Biology and Ecosystems “Essential Ocean Variables (EOVs)” and at least 53% (39/73) of these EOV’s sub-variables. The systems also measure litter, plastics, biotoxins, parasites, pathogens and organic pollutants of relevance to the Marine Strategy Framework Directive (MSFD) as well as fisheries, aquaculture and offshore industries. The sensors include: i) an in situ analyser for Nucleic Acids (DNA and RNA) including eDNA for quantifying species and genes; Lab on a chip (LOC) sensors that will sense ii) nutrients and the carbonate EOVs; and iii) organic contaminants and toxins detected with recombinant antibodies; iv) a primary productivity sensor using time resolved fluorescence; and v) a micro (LOC) cytometer for microorganisms and microplastics. The imaging systems will demonstrate the new image workflow and target benthic (seabed) and pelagic (water column) biology and plastic. The sampler collects up to 1000 particle samples and can be used for plastics, microorganisms and eDNA for later analysis (e.g. sequencing of nucleic acids.) TechOceanS will demonstrate technologies at two sites (Naples, Gran Canaria) for science, aquaculture, fisheries, regulator and industrial users. The project will both develop and use best practices, and will collaborate and disseminate widely with stakeholders and the international community including by hosting training events on ocean observing technologies. TechOceanS expects to commercialise the technologies resulting from this project.

Keywords: sensors,microfluidics,lab on chip,nucleic acid,sequencing,genomic,recombinant antibody,biotoxin,organic,contaminant,cytometer
Regional Futures: The territorial politics of digitalisation-as-urbanisation in the global south (REGFUT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: India,United Kingdom,Mexico,United Kingdom
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2022-01-01
End date: 2026-12-31
Duration (months): 60.0
Total project cost (EUR): 2499862.0
EU funding (EUR): 2102405.75
Participants: 4
Project status: SIGNED

In the last two decades, an information revolution in the global south has profoundly shaped the urbanisation of metropolitan regions. Global and national initiatives to adopt smart technologies in local governments, with the claim that opportunities presented by digitalisation will resolve the challenges of urbanisation – are now literally automating regional futures. This project will conduct the first comprehensive South-South investigation of the dynamics of digitalisation-as-urbanisation – the transition to automated planning processes in metropolitan regions, and its impacts on regional urbanisation. The project will conduct research in peri-urban municipalities of three rapidly growing metropolitan regions of the global south where municipal digitalisation is directed towards strategic regional planning. These municipalities face major challenges with transforming paper-based colonial and postcolonial bureaucracies into automated planning processes within highly unequal contexts, and therefore represent the wider experience of digitalisation-as-urbanisation in the global south. Through detailed ethnography, interviews and information audit trails in digitalising municipalities, the project will investigate a) the rescaling of governance to the local digitalising state; b) the territorialisation of information infrastructures; and c) territorial politics of digitalisation. It will examine how digitalisation produces new territories for regional urbanisation and how state and non-state actors are assisting, contesting and disrupting these regional futures. It will bring to fruition the applicant’s agenda setting work on postcolonial urban futures, smart cities, digital citizenships and recent work on the governance of small cities in the global south. The project will build new theories and detailed empirical evidence of southern urbanisation as both a product and a producer of the ‘information revolution’ in the global south.

Keywords: digitalising state,regional future,urbanisation,information revolution,municipal governance
Quantum Decision Making (QDM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-10-01
End date: 2018-10-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

This proposal concerns the formal and descriptive foundations of belief updating (BU) in human decision making. What are the principles that guide change in beliefs, as evidence accumulates? The dominant approach in decision making has been classical, Bayesian probability theory (CPT). Yet persistent discrepancies between CPT prescription and human behaviour challenge this dominance. Are there analogous findings in BU? If yes, if CPT cannot provide a satisfactory account of BU, what is a suitable alternative formal framework? We will carefully consider surprising empirical tests of the adequacy of CPT in belief updating, inspired by quantum probability theory (QPT). The recently emerging QPT decision models have been revolutionarizing insight about the formal principles guiding decision making. Prediction insights for BU call for more advanced techniques in QPT, such as open-system dynamics. The Experienced Researcher(ER) has an outstanding track record in quantum foundations and is seeking a career transition to cognitive psychology. The Supervisor is one of the pioneers of the application of QPT in cognitive psychology. This highly inter-disciplinary, innovative proposal will converge QPT technical expertise and deep, unaddressed questions in decision making. CITY is already one of the internationally leading centres for cognitive research based on QPT methods, with experts spanning computer science, economics, physics and cognitive psychology. This is the perfect environment to enable the ER to apply her expertise, flourish, and mature into one of the leading figures in this emerging research area. Finally, formalizing the principles of BU is a key challenge not only for cognitive psychology, but any area where there is a need for rigorous models of belief change, as a result of accumulating evidence (e.g., artificial intelligence). This proposal will be a major step towards a fully comprehensive, technically sophisticated, and empirically accurate theory.

Keywords: decision making,prisoner s dilemma,quantum probability theory,mathematical models of cognition
BRAKE DIsc for AutoMotive - performance enhancement by insertion of diamond particles (BrakeDiam)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Italy
Call: Small business innovation research for Transport (H2020-SMEINST-1-2015, 2015)
Start date: 2015-11-01
End date: 2016-02-29
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Created in Grezzana (Italy) in 2013, our company, Ferdiam S.r.l., is a “startup” company dedicated to the development of innovative technologies and products through the use of the diamond. As a spin-off Dellas S.p.a., world-renowned leader for over 40 years in the manufacturing of diamond-based tools for cutting stone, we have a solid and proven knowledge of the potential of the diamond for industrial applications and its subsequent business exploitation. Diamonds have unsurpassed hardness among minerals on Earth (according to the Mohs scale). Their thermal conductivity is extremely high (5 times higher than 2nd ranked, Copper) that leads to practical 20-times better thermal-dissipation than other industrial materials (e.g. iron, steel). These, together with other properties (broad band optical transparency; extremely chemically inert-not affected by any acid or other chemicals; graphitization only at very high temperatures) make them a very versatile material for industrial purposes. Originally focused on the decorative world thanks to the diamond’s characteristics of brightness and resistance, our business development has evolved as well towards the automotive sector where its thermal conductivity and hardness can address current needs towards higher performances of the disc brakes, crucial systems of the automotive. Using diamonds, BrakeDiam, our innovative brake for automotive industry, means a new push forward in braking technology, improving the complete braking system in standard tourism cars and motorbikes: safer (braking time to stop vehicle is reduced by 15%), optimized gas consumption (braking system 25% lighter), less maintenance (+40% operating life) and environmental friendly (-50% particle emissions of steel/iron dust). This project, which aims at producing and commercializing our BrakeDiam disc brake range, will allow us to grow sustainably through an accumulated profit over 12 million within the first 5 years of exploitation.

Keywords: brake disc,weight diamond,heat dissipation,automotive,motorbike,safety
Micro-RNAs of neutrophils in renal ANCA-associated vasculitis (MINERVA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-04-01
End date: 2018-07-22
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

Activation of neutrophils by ANCA (“Anti-Neutrophil Cytoplasm Antibodies”) and subsequent endothelial cell (EC) damage is the main feature of ANCA-associated vasculitis (AAV). There is no specific treatment for AAV to date and 25% of patients evolve towards end-stage renal disease requiring dialysis and renal transplantation. While accumulating data indicate that miRNAs control major biological responses in various cell types including EC and neutrophils and are involved in the pathophysiology of several diseases, their role in AAV has been virtually unexplored. In addition, recent studies have shown that ANCA-activated neutrophils can induce EC damage through the release of microparticles, but while many studies have revealed a critical role for miRNAs secreted within microparticles in intracellular crosstalks, there is no data so far on the role of miRNAs in this process. Here, we propose to identify miRNAs deregulated in neutrophils exposed to ANCA and released in microparticles that promote EC damage in AAV. These miRNAs will be identified using TaqMan Low Density Arrays in ANCA-stimulated neutrophils in vitro and in the microparticles they release, as well as in neutrophils from patients with AAV. To assess whether these miRNAs could be used as biomarkers, their expression will also be analyzed in plasma and urine samples from AAV patients, and correlated with severity and outcome of the disease. The transfer of neutrophil-secreted miRNAs to EC will be assessed in vitro, and the function of these miRNAs in the regulation of EC responses (activation, angiogenesis) will be studied in various functional assays. While miRNAs are emerging as new therapeutic tools for several diseases, this translational study will provide the first data regarding the expression and function of neutrophil miRNAs in AAV and may therefore pave the way for novel promising miRNA-based therapeutic options in these patients.

Keywords: anca associated vasculitis,mirna,neutrophils,endothelial cells,microparticles
Human gut Microbiome, gene Expression and Colorectal Cancer: Assigning causal roles from a novel Mendelian randomization perspective. (MECoCaM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-09-03
End date: 2020-09-02
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

The contribution of the gut microbial ecosystem to colorectal cancer (CRC) is not well understood. Inflammatory processes and unbalance cell proliferation in the host could be behind observed correlations between a microbe and cancer stages. However, the enrichment of a microbe at a tumour site does not directly assume causation. Rather, this could be the result of a reverse causation or a confounding third factor. Therefore, two major challenges unravelling CRC aetiology are (i) to identify the mechanistic interactions of microbial communities with host intestinal epithelium cells, and (ii) to assign causality to carcinogenesis. These are the aims of this project integrating different “omic” data, and using a Mendelian randomization (MR) approach. In this study we analyse microbiome sequencing data, from up to 500 normal colon mucosa biopsies, to provide a comprehensive description of the gut microbiome. Additionally, we integrate transcriptomic data from these well phenotyped 500 samples to understand the interaction between microbes and the gut epithelial cells. Finally, using the germ-line genetic variation of host cells as a third “omic” layer, the correlations between microbes and (i) environmental exposures, (ii) gene expression, and (iii) CRC can be validated by MR. MR is an analytical approach whereby germ-line genetic markers are used as proxies – or instrumental variables – for putative risk factors. These genetic markers cannot be influenced by reverse causation, and, assuming an absence of pleiotropy, can provide unconfounded estimates of association. Therefore, a MR association between genetic proxies and the outcome of interest would indicate that the exposure being proxied is associated in a causal manner. The identification of the functional relevance and key mediators of gut microbiome to colorectal cancer development is going to increase the development of therapeutic approaches and prevention strategies.

Keywords: colorectal cancer,mendelian randomization,gut microbiome sequencing,gene expression analysis,enviromental life style factors
Carbon coated Silicon Production Scaling Up for Li-ion batteries (DEBIMAX)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-11-01
End date: 2023-01-31
Duration (months): 39.0
Total project cost (EUR): 2509933.75
EU funding (EUR): 1756953.63
Participants: 1
Project status: SIGNED

The booming need for batteries and higher storage capacities are well identified challenges. Increase production capacities can meet the higher demand but improved storage capacities require innovation and new battery materials. The critical application for better capacities is the automotive electric vehicles market for which the vehicle range is a key drag on market growth. Nanomakers’ solution is to supply a new material for batteries anodes. This high-quality material is already available for niche market (portable electronics) and can be used to triple battery anodes capacities. To address automotive mass market, this product has also to be cheap and available at large scale, both of which are the main object of this project. This will be done by increasing nanomakers’ production capacity fourfold per reactor. Nanomakers is a french R&D company, spin-off from cea which is producing and selling at industrial scale Si and Sic nanoparticles made by laser pyrolysis, a patented technology developed at cea. In 2012, the company patented a new product: carbon coated silicon (SiwC) as anode active material for li-ion batteries. This material triples the anodes capacity and will partly replace natural graphite which a critical raw material currently used in batteries. With a compound annual growth rate of around 20%, li-ion battery market will be significant in the years to come. This growth will be first driven by portable electronics and then by automotive industry where battery price must be competitive. Nanomakers has a long experience and feed-back form customers that helped optimizing its product (size, coating, …). Since 2013, nanomakers has been providing most of the battery actors, especially in asia. So, nanomakers want to set up Debimax project to meet the large capacity demand and reduces the production costs for portable electronics and automotive industry.

Keywords: li ion battery,silicon,energy efficiency,scaling up process,anode
Single-Emitter Quantum Optics and Optomechanics (SEQOO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain,United States
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-04-01
End date: 2020-03-30
Duration (months): 36.0
Total project cost (EUR): 257191.2
EU funding (EUR): 257191.2
Participants: 2
Project status: CLOSED

The main goal of SEQOO is to realize hybrid quantum systems based on NV-centers in diamond and nanomechanical oscillators. Hybrid quantum systems combine two or more physical systems (e.g. spins, photons, phonons), with the goal of harnessing the advantages and strengths of the different systems in order to better explore new phenomena and potentially bring about novel quantum technologies. While spins and phonons are ideal candidates to store quantum information, photons are ideal carriers of quantum information over long distances. Additionally, mechanical systems can be influenced by a wide variety of small forces and, therefore, present themselves as natural interconnects to realize hybrid systems. Here we focus two realizations of hybrid systems based on Nitrogen Vacancy color center in diamond (NV-center) coupled to a mechanical resonator. The first system consists of an optomechanical crystal (OMC) structure with co-localized photonic and phononic modes, which is formed around the NV defect in the diamond host material. This hybrid system realizes a Spin-Photon-Interface (SPI) operating in the low loss Telecommunications band (TeSPI), which allows for low loss transmission via optical fibres and thereby for connecting spatially separate quantum systems. This is extremely important to realize large-scale quantum networks. The second system consists of a levitated nanodiamond containing a NV-center in a strong magnetic field gradient. The field gradient renders the NVs electronic spin energy dependent on the nanodiamond position and enables cooling of the nanoresonator or preparation of non-classical mechanical states through spin-dependent forces. The Spin Controlled Levitated nanodiamond (SCoL) opens up exciting routes toward studying quantum mechanical effects in macroscopic objects. The proposed research will be carried out in a concerted effort between myself (Dr. Jan Gieseler), Prof. Mikhail Lukin (Harvard University) and Prof. Romain Quidant (ICFO).

Keywords: optomechanics,diamond,nv center,quantum frequency conversion