Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
METROFOOD-RI Preparatory Phase Project (METROFOOD-PP)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Coordination and support actions
Countries involved: Germany,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Spain,Italy,Moldova, Republic of,North Macedonia,Norway,Greece,Greece,Greece,Greece,Hungary,Slovenia,Türkiye,Belgium,Finland,Romania,Slovenia,Slovenia,Switzerland,France,France,France,Czechia,Netherlands,Netherlands,Portugal
Call: Preparatory Phase of new ESFRI projects and early phase support to ESFRI high strategic potential areas (H2020-INFRADEV-2019-2, 2019)
Start date: 2019-12-01
End date: 2022-05-31
Duration (months): 30.0
Total project cost (EUR): 3999890.0
EU funding (EUR): 3999890.0
Participants: 48
Project status: CLOSED

METROFOOD-RI – Infrastructure for Promoting Metrology in Food and Nutrition - is a pan-European Research Infrastructure (RI) aimed to promote scientific excellence in the field of food quality and safety. It provides high-quality metrology services in food and nutrition, comprising an important cross-section of highly interdisciplinary and interconnected fields throughout the food value chain, including agrifood, sustainable development, food safety, quality, traceability and authenticity, environmental safety, and human health. METROFOOD-RI has been selected to the ESFRI Roadmap2018 as mature enough to be implemented within the next ten years. The Action is aimed to support METROFOOD-RI to grow from its current status (research-based network of facilities and skills) to a mature, centrally-coordinated, integrated RI, with the legal, financial and technical maturity required for implementing it. The main objective is to develop the organizational, operational and strategic framework of METROFOOD-RI. Activities include legal, governance, financial, technical, strategic and administrative aspects carried out in 15 work packages, organised in 3 blocks dedicated respectively to: the organisation of the legal entity that will manage the future RI, i.e. ERIC; define the operation and the operational standards at the level of the whole RI and for the National Nodes, as well as the role of the RI as service-oriented organisation; define the long term activities for the future RI and update the Strategic Research & Innovation Agenda, in response to the actual and future challenges in the agrifood sector and for the Society. The main outcome will be the establishment of legal and financial commitment for the future ERIC, ensuring long-term common commitment, decision-making and funding engagement. Continuous relations with stakeholders and the user community will be kept in order to ensure the addressing of their needs at the best, and to focus strategies and planned services

Keywords: research infrastructure,health and food,metrology in food and nutrition,services to users,legal entity,governance,financial plan,central hub and national nodes,strategic planning
High-throughput combinatorial chemical protein synthesis as a novel research technology platform for chemical and synthetic biology (HiChemSynPro)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: France
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-03-01
End date: 2023-02-28
Duration (months): 72.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 2
Project status: SIGNED

Chemical protein synthesis is an indispensable method in chemical and synthetic biology. However, at the present moment, it is laborious and involves multiple optimization and purification steps. High-throughput approaches for total synthesis of combinatorial libraries of custom-modified protein variants are needed. To change the situation, the work will be carried out in two directions: (1) implementation of microfluidic techniques for automation, miniaturization and multiplexing of experimental steps involved in the total synthesis of proteins, and (2) design and synthesis of novel catalytic proteins for efficient enzyme-assisted peptide ligations under denatured conditions. This innovative research technology will allow robust chemical synthesis of protein libraries with (100–10,000)-compounds with natural and unnatural modifications, bearing variety of post-translational modifications and also protein-like biopolymers. In this project, the new methodology will be validated by chemical synthesis of library of phosphorylated analogues of high mobility group protein A (HMGA), which is involved in gene-transcription and cancer development. Other potential future applications include protein design, biological problems where post-translational modifications play a crucial role (ranging from the ‘histone code’ hypothesis to understanding long-term memory) and functional annotation of newly discovered genes.

Keywords: chemical protein synthesis,microfluidics,enzyme engineering,post translational modifications,combinatorial protein libraries
IN-depth SPatiotemporal dissection of autoimmunity-induced Inflammation in RhEumatoid arthritis (INSPIRE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Germany,Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-07-01
End date: 2026-12-31
Duration (months): 66.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 1923297.0
Participants: 2
Project status: SIGNED

Rheumatoid Arthritis (RA) is a prototypic T cell- and B cell-driven inflammatory autoimmune disease that affects around 1% of the population worldwide and creates a severe burden for patients as well as substantial socioeconomic costs for society. Hallmarks of RA are a destructive inflammation of peripheral joints as well as the presence of autoantibodies such as anti-citrullinated protein antibodies (ACPA). Although ACPA are considered to represent major drivers of RA pathology, they can be also found in otherwise healthy “individuals at risk” where they emerge decades before the eventual onset of RA. Factors and mechanisms that promote onset of tissue inflammation in such autoantibody-positive individuals still remain elusive. Due to this gap of knowledge, current therapies are primarily designed to suppress later stages of joint inflammation, rather than targeting the underlying processes of autoimmunity or the initial onset of inflammatory disease. RA patients thus still lack effective preventive or curative therapeutic concepts. Here we aim to exploit recent technical breakthroughs such as single-cell RNA- and ATAC-sequencing in conjunction with DNA bar-coded MHC dextramers and antigens, spatial transcriptomics and cutting-edge imaging to perform a comprehensive and in-depth spatiotemporal analysis of the molecular events underlying the initial onset of inflammatory disease in autoantibody-positive individuals. We will additionally profit from the access to a large and well-characterized cohort of ACPA-positive “individuals at risk” and ACPA-positive RA patients as well as from corresponding biomaterial. In combination with preclinical animal models of RA, we thereby seek to delineate the sequences of events that promote the early transition from autoimmunity to inflammation. The obtained data will yield key insights into basic mechanisms of inflammatory autoimmune diseases such as RA and provide the basis for novel treatment concepts.
MEETmeTONIGHT (MEET)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Italy,Italy
Call: European Researchers' Night (H2020-MSCA-NIGHT-2018, 2018)
Start date: 2018-05-01
End date: 2019-12-31
Duration (months): 20.0
Total project cost (EUR): 720125.0
EU funding (EUR): 360000.0
Participants: 5
Project status: CLOSED

MEETmeTONIGHT (MEET) – “Face to face with the research” is the proposal for the European Researchers’ Night in 2018/19, happening in the two major Italian cities of Milano and Napoli, complemented by Brescia, Castellanza, Cremona, Edolo, Lecco, Lodi, Mantova, Monza, Pavia Sondrio (Lombardia region), Portici and Procida (Campania region). The goal is to realize a special occasion of meeting and interaction between the public at large and the world of research, where researchers – at the forefront of all the proposed activities – can show themselves and what they do, in a simple, spontaneous, informal and entertaining way, actively involving the public. People, by doing, find themselves learning, getting amused, and becoming aware of how much research is for everyone and all around us. All MEET activities aim at promoting research and its outcomes, researchers and their profession, with a special attention to the youngest generations on one side, and to the recognition of the role of Europe on the other. With five thematic areas and five flagship topics, MEET proposes interactive stands, hands-on experiments and live demos that reconstruct the research environment; conferences, video projections, interactive games; guided visits to scientific museums; meeting occasions with researchers; European Corners; live broadcast moments. A special attention is given to schools’ pupils, for which a number of dedicated activities are foreseen, at the goal of encouraging them to consider research career as a concrete option for their life.

Keywords: responsible research and innovation,public engagement,outreach,interaction,entertainment,citizen science
Improved Resilience and Sustainable Reconstruction of Cultural Heritage Areas to cope with Climate Change and Other Hazards based on Innovative Algorithms and Modelling Tools (YADES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Italy,Cyprus,Greece,Finland,Switzerland,Greece,Lithuania
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2019, 2019)
Start date: 2020-04-01
End date: 2025-03-31
Duration (months): 60.0
Total project cost (EUR): 1909000.0
EU funding (EUR): 1909000.0
Participants: 10
Project status: SIGNED

YADES aims to efficiently train a network of fellows on the field of the resilience of Cultural Heritage (CH) areas and historic cities against Climate Change (CC) and other types of hazards. Towards this direction, YADES aims to introduce a research framework for downscaling the created climate and atmospheric composition as well as associated risk maps down to the 1x1 km (historic area) scale, and specific damage functions for CH materials. Applying atmospheric modelling for specific CC scenarios at such refined spatial and time scales allows for an accurate quantitative and qualitative impact assessment of the estimated micro-climatic and atmospheric stressors. YADES will perform combined structural/geotechnical analysis of the CH sites and damage assessment under normal and changed conditions, based on the climatic zone, the micro-climate conditions, the petrographic and textural features of building materials, historic data for the structures, the effect of previous restoration processes and the environmental/physical characteristics of the surrounding environment. The data coming from installed monitoring system will be coupled with simulated data (under our cultural heritage resilience assessment platform-CHRAP) and will be further analysed through our data management system, while supporting communities’ participation and public awareness. The data from the monitoring system will feed the DSS so as to provide proper adaptation and mitigation strategies. The produced vulnerability map will be used by the local authorities to assess the threats of CC (and other natural hazards), visualize the built heritage and cultural landscape under future climate scenarios, model the effects of different adaptation strategies, and ultimately prioritize any rehabilitation actions to best allocate funds in both pre- and post-event environments. To train the fellows, the project will make use of extensive workshop and training sessions, as well organise summer schools.

Keywords: resilience of cultural heritage areas against climate change and other hazards,modelling tools,decision support system,remote sensing,computer vision,artificial intelligence
Auto-Producing TV Broadcasting System for Sport Events (Keemotion)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Belgium
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Sport event broadcast is too expensive: a single match costs €9,000-€30,000 and requires intensive equipment installation and manual operation in situ. Minority or emerging sports find tremendous difficulties to keep on stage and gain penetration (example: female sports are only 16-20%). Additionally, broadcasting infrastructure produces intrusion in the facilities and cannot be leveraged to be used for other purposes (i.e. replay analysis, coach tactics analysis, etc.) and capital expenditure of broadcasting rights in top-tier leagues and teams is increasing the breach with 2nd-tier and local teams. As a result, there is a need to reduce the cost and infrastructure to broadcast a match, considering younger population preference is moving from TV to social media and online devices, most of the huge amount of data produced during a match is missed when there is no recording mean or can be only interpreted by human analysis Keemotion is a hardware + software solution to produce live online broadcasts of basketball and other indoor matches with unmanned operation and minimum equipment, that is, affordable price for leagues, coaches and broadcasters. It consists of a single device with 3 cameras + Artificial Intelligence for automated virtual camera; a virtual camera that simulates the movement of typical TV broadcasts with human operators; smart tagging feature to provide advanced analytics about the match and players’ performance; instant replay for referee assistance and real-time streaming broadcast for all digital devices (mobile, smart TV, computers) including integration with social media. Our customers (leagues, coaches/teams and broadcasters) will benefit from: - 80% savings Vs. conventional broadcasting - A turnkey solution (zero setup effort) - No transportation and no operators For us, it will represent a SaaS model, recurring revenue from SW licenses, worldwide expansion (EU, USA & Japan first) and valuable IP assets: automated production technology

Keywords: artificial intelligence,virtual camera,tv broadcasts,smart tagging feature,advanced analytics,performance,instant replay,sports
HYdro-POwer-Suite (HYPOS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Innovation actions
Countries involved: Italy,Germany,Norway,Sweden,Switzerland
Call: Copernicus market uptake (H2020-SPACE-2019, 2019)
Start date: 2019-12-01
End date: 2022-11-30
Duration (months): 36.0
Total project cost (EUR): 2397120.0
EU funding (EUR): 1994370.0
Participants: 5
Project status: CLOSED

Hydropower as the world’s largest source of renewable energy still has a high unused potential to be explored in times of a changing global energy policy. The economic and ecological evaluation of new hydropower developments rely on a number of environmental conditions, such as key hydrological parameters. For example, the major drivers of the reservoir storage capacity over time, reservoir life time, and also a major driver of the operations costs are directly related to the sediment regime and sediment trapping. HYPOS is catalyzing innovation with an operational service for appropriate environmental and economic investment planning and monitoring based on Earth Observation (EO) technologies and modelling for the Hydropower industry. The to developed online accessible Decision Support Tool will provide essential assets for hydro power managers, planners and decision makers in their work. The subscription portal brings together high-quality satellite based measurements for historic time periods, actual current monitoring, up-to-date modelled hydrological parameters, with nowcasting on various orderable levels of detail and available in-situ data for integrated baseline and environmental impact assessments. The service significantly contributes on a trans-national as well as a global scale, with the requirement of independent, standardized and consistent information over a wide range of different water bodies and spatial scales. Substantial Blue Footprint analysis are enabled based on sophisticated and state-of-the-art algorithms and methodology featuring sustainable long-term monitoring solutions.
Modular representation theory of reductive algebraic groups and local Geometric Langlands duality (RedLang)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Germany,France
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 1268551.0
EU funding (EUR): 918461.0
Participants: 2
Project status: SIGNED

In the recent years the PI has been involved in several breakthrough results in the representation theory of reductive algebraic groups (in particular related to the computation of character formulas for simple and indecomposable tilting modules), obtained using various techniques (in particular geometry and categorification). The present proposal aims at: 1. exploring the new perspectives offered by these results, which go beyond the computation of characters, and by the techniques we have already developed; 2. developing new geometric tools to support these advances. Our main geometric input will be the development of a modular Local Geometric Langlands duality, in the spirit of work of Bezrukavnikov for characteristic-0 coefficients, and of a modular "ramified" geometric Satake equivalence. We expect in particular applications in the study of tilting modules (e.g. their behaviour under restriction to reductive subgroups, and their multiplicative properties), and to the description of the center of the distribution algebra (with a view towards understanding the "higher linkage" phenomena).

Keywords: representation theory,perverse sheaves
Turning carbon of complex organic urban waste streams into value-added products (CIRCULAR BIOCARBON)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Public-private partnerships
Destination: Bio-based Industries
Action type: Innovation actions
Partnership: BBI (Art-187)
Countries involved: Spain,Spain,Italy,Italy,Italy,Germany,Spain,Spain,France,Denmark
Call: Valorise the organic fraction of municipal solid waste through an integrated biorefinery at commercial level (H2020-BBI-JTI-2020, 2020)
Start date: 2021-06-01
End date: 2026-05-31
Duration (months): 60.0
Total project cost (EUR): 22952297.5
EU funding (EUR): 14999999.75
Participants: 11
Project status: SIGNED

CIRCULAR BIOCARBON is a first-of-its-kind flagship biorefinery conceived to valorise organic fraction of municipal solid waste (OFMSW) into value-added products: diamond-like-carbon coatings, green graphene, tailor-made bio-based fertilisers, or bio-plastic, as well as a variety of intermediate products. In order to maximise replicability and boost potential penetration in the market, the biorefinery will be operated for three years in Spain and Italy, and consistent business and exploitation strategies will be put in place. The CIRCULAR BIOCARBON biorefinery, organised through a pool of cascading technologies, start from anaerobic process steps (after proper pretreatment) of mixed urban waste streams, of which OFMSW is the main one, in order to treat all the biowaste produced by a medium-size city (at the end of the project, a commercial scale biorefinery will be fully operative). The fundamental objective of the CIRCULAR BIOCARBON project is to open up new business frameworks based on a new circular vision of waste treatment in a city towards a sustainable bioeconomy, to which actors leading the territorial waste management schemes and policies will be brought to maximize impact on the market, on policy makers and on society.

Keywords: flagship integrated biorefinery,ofmsw,circular economy,high added value products,replicability,territorial politics integration,market opening,industry and agriculture sector,green europe