Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
pREcise Fluids mEteRing EquipmEnt (REFEREE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Italy
Call: Small business innovation research for Transport (H2020-SMEINST-1-2014, 2014)
Start date: 2015-01-01
End date: 2015-04-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

No one likes to be cheated, neither on purpose, nor accidentally. 2014/32/EU Measuring Instrument Directive (MID), mandatory from April 2016 on, works towards guaranteeing the rights of the end consumer, as well as providing an uniform European Market for all manufacturers of Measurement Instruments (MIs). We are FLEXBIMEC International SRL, an Italian multinational company situated in Albinea (North of Italy) with 26 employees, 8.6M€ turnover, 2,500 customers base and a track record of 40+ years experience successfully providing MIs for fluid/fuel metering and dispensing devices. We lead the Italian market (>35% market quote) and are a relevant European and worldwide player (>55% exports). Passionate about innovation, as we are, we will take this EU directive as an opportunity to commit a deep revision of our current technology and go a step further in the direction of offering our customers the added value they deserve while further protecting end consumer rights. REFEREE is a technology upon which we will build a brand new line of fluids metering & dispensing equipment conforming 2014/32/EU MID Norm, that will comprise an optional proprietary air separation subsystem (to further increase accuracy, equipment lifetime, make the workplace safer and cleaner for workers and lower environmental impact). We will focus on Automotive (our all-time focus), Industrial (mechanical industry of production of cylinders, cranes, gear reducers, vehicles and motors) and will start exploring Maritime (new market!) sectors, and specifically target electric oil and fuel pumps in the garage segment. Results obtained from our on-going development makes us confident in achieving our goal of further increasing our sales up to 60% in the EU and consolidate our international presence.

Keywords: fluids metering,measuring instruments,dispensing,2014
Think!EHR Platform as vendor-neutral, open health data platform, designed for real-time, transactional health data storage enabling to go from idea to application in one hour. (ThinkEHR Platform)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Slovenia
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2014-10-01
End date: 2015-02-28
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Governments, regions and healthcare organizations are beginning to realize that the real value of health IT is not in application but in data. Better data is a key to improving outcomes, managing chronic diseases, managing population health and must be kept and accessed for the lifetime of the patient. Health IT vendors are developing monolithic healthcare applications covering all specialties with wide range of functionalities and proprietary health data models that were not designed for data outliving the application, making care coordination and lifelong health records difficult. Furthermore IT health data market is very competitive business environment, controlled by mega-vendors. Small companies and start-ups are facing severe difficulties when entering the market as these large corporations offer monolithic EHR solutions and lock-in their customers. Personalized IT solutions solving specific needs of health organisations are in these cases practically impossible to implement. Therefore it is not only necessary but critical to provide a vendor-neutral, big-data, high-performance platform designed to store,manage,query, retrieve and exchange structured electronic health record data based on open health data standards. The Think!EHR Platform is based on open, community sourced clinical data models while providing the APIs and tools enabeling app developers to focus on innovation, new solution and easy clinical data management. Vendors relying on the platforms solid foundation, built in clinical data repository and the tools will benefit from reduced time to market and lower development costs. With feasibility study we will verify the technological and economic viability of Think!EHR Platform as a product focusing on discovering technological and marketing bottlenecks and new opportunities. Based on outcomes we will prepare business plan with detailed marketing strategy for selected markets, described target stakeholders and approaches for each specific segment.

Keywords: open ehalth data platform,realt time analytics,jumpstart development,state of the art healthcare apps and applications
high capacity planet BEAring Technology for High Efficiency gearbox (BrEATHE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: France
Call: Gearbox bearing design & testing (H2020-CS2-CFP07-2017-02, 2017)
Start date: 2019-01-01
End date: 2022-04-30
Duration (months): 40.0
Total project cost (EUR): 998918.0
EU funding (EUR): 998918.0
Participants: 2
Project status: SIGNED

The Ultra High By-pass Ratio (UHBR) engine provides environmental benefits through a high power gearbox decoupling fan and turbine speeds. To implement such engine different technological issues raise: the increase of the i) rotational speed, ii) harsh lubrication conditions and iii) power density. The design of the rolling bearing, crucial component, can affect the gearbox and engine efficiency, performance and reliability. The aim of BrEATHE is to develop, design, model and test a rolling bearing to be mounted in a high power gearbox, including investigation for new high loaded materials, development of models to predicts bearing behavior, producing samples and test them in dedicated test bench. Specific project objectives are: - To define the geometry and perform the design of the bearing. To predict heat generation and transfer in the planet bearing through interactions between dynamic and thermal behaviours. - To demonstrate a -30% in power loss & oil flow and a 15% increase in rolling contact stress capability in comparison to the current baseline solutions and without any detrimental effect on reliability. - To assess the benefits of different process technologies and materials in reaching the efficiency and stress capability required by the gearbox and engine architecture. Including design optimization, comparison of different case hardened steel grade coupled with ceramic rolling elements. - To produce a sufficient number of bearings to sustain the test plan based on a dedicated test bench. To demonstrate their enhanced performances, the BrEATHE new bearing technologies will firstly assessed through modelling and then testes in full-scale testing, with full duty cycle representing the real flight spectrum. The gained theoretical knowledge will enable the transfer and exploitation of projects results to the industrial field by providing analysis tools and new design rules.

Keywords: high capacity planet bearing,geabox,test bench,model validation
Development of a business model to commercialise GPU accelerated workstations for European hardware providers (CGACE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: United Kingdom
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2020-01-31
Duration (months): 8.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Company: We (ebb3 Ltd), an accredited specialist systems integrator are developing software in partnership with market leading technology providers (Cisco, Citrix & Nvidia). Our partners have been selected specifically for their interoperability and global market positioning. ebb3 will use our partners existing software and hardware components as the foundation to provide and manage a common GPU (Graphical Processing Unit) accelerated computing platform. Problem: Whilst many organisations are moving their data into the cloud, there are applications and workloads confined to physical workstation computers where the GPU is commonly located and not cloud compatible. As workstation applications become more complex and resource demanding, their data files become even larger. This data transfer to and from the cloud is time consuming and impacts an organisations security data availability policies and risks the value of the data. State-of-the-art: All the current virtual workstation solutions, are either public or private shared cloud solutions, meaning that they are also in a public cloud, with multi-tenant pooling of resources among multiple customers, increasing issues of data privacy and security. In addition, cloud-based solutions often require dedicated resources creating islands of technology that become cumbersome and costly to maintain and support. Most virtual workstation solutions do not manage the set-up, user resource pool usage or provide support services when the workstation is not performing, meaning users experience periods of high latency, poor performance and difficulty accessing resources. Our solution: ebb3 offers customers a fully managed, private cloud dedicated common GPU accelerated computing environment (CGACE) that uses an AI resource management tool for effective resource utilisation, allowing no feeling of latency for the user and freeing up resources in the datacentre for VR, ML and high performance applications.

Keywords: high performance virtual computing,virtual workstation,gpu applications,cloud computing,databases
Organsation of the European Research Community on Nuclear Materials (ORIENT-NM)

Framework: Horizon 2020 — Euratom
Programme: Nuclear fission and radiation protection
Theme: Nuclear safety
Action type: Coordination and support actions
Countries involved: Germany,Italy,Spain,Belgium,Sweden,Romania,Finland,Poland,France,Czechia,Netherlands
Call: Towards joint European effort in area of nuclear materials (NFRP-2019-2020, 2019)
Start date: 2020-10-01
End date: 2023-03-31
Duration (months): 30.0
Total project cost (EUR): 1756380.0
EU funding (EUR): 1099588.75
Participants: 15
Project status: SIGNED

ORIENT-NM answers the Euratom WP 2019-20 call NFRP-08, which requests to explore the possibility of establishing a European Joint Programme (EJP) on nuclear materials. Accordingly, ORIENT-NM will: 1. Produce a convincing strategic research agenda (SRA) for materials for all nuclear fission reactor generations (until 2040), consistent with national programmes and industrial needs, including supply chain constraints, paying attention to standardisation issues and verifying the availability of suitable infrastructures; 2. Elaborate an efficient EJP governance and legal structure, including attention for decision-making processes, intellectual property issues, promotion of innovation and analysis of potentially available resources, as well as an implementation scheme caring among others for quality assurance, SRA updating, knowledge and data management; all this considering different possible scenarios; 3. To identify appropriate ways of interactions between the EJP and other bodies and initiatives that bear connections with nuclear materials (stake-holders), including international organisations, standardisation bodies, technical safety organisations, fusion and non-nuclear energy communities, other associations, while addressing the issue of a coordinated use of nuclear materials infrastructures. All of the above will be done in close dialogue with Member States and European Commission, as well as all other stake-holders, in order to meet their requirements and expectations from an EJP on nuclear materials and raise the interest of identified research owners and research managers, by demonstrating the added value of such EJP. The key outcomes will be: A. Critical assessment of the added value of an EJP on nuclear materials; B. Vision Paper and SRA; C. Possible EJP structure, governance, legal aspects and implementation; D. Set of protocols for the interaction of the EJP with other stake-holders. Documents listed under A, C and D will complement and integrate the SRA.

Keywords: preparation of a european joint programme on nuclear materials
Labelling of engineered nanomaterials for nanosafety tracing (NanoLabels)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-02-01
End date: 2020-02-27
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Major uncertainty still exists on the safety of engineered nanomaterials (ENMs). This is primarily due to difficulties in studying such small-scale objects and especially tracing their fate and behaviour in laboratory experiments and, even more so, the environment. Labelling of ENMs can serve a very important role of tracer in the environment, and ultimately be used as a tool to create unique ENM identities and support the concept of “safer-by-design”. The proposed project will compare different labelling techniques, both conventional (fluorescent labels) and emerging (stable isotopic and chemical labelling) where the host and ER have complementary expertise, and investigate multiple labels. It will consider aspects of industrial synthesis and scaling up and carry out a field experiment involving labelled ENMs. The ER will be hosted by the team who pioneered stable isotope labelling of ENMs and benefit from placements with the JRC and Glantreo, whilst bringing to the project his own unique expertise on ENM synthesis and tracing.

Keywords: nanosafety,nanomaterial libraries,nanotoxicology,safety by design,stable isotope labels,radiolabels,fluorescent labels
Substainable and efficient food processing and cooking sytem (Efficient Cooking)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: Spain
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-1-2014, 2014)
Start date: 2015-05-01
End date: 2015-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Natural Machines is a SME that has created the first 3D food printer that works with sweet and savory ingredients. We are focused on helping people get back to home cooking, back to healthy food, by bringing the food processing plant to the home kitchens, giving an eco-efficient alternative to traditional food processing, reducing food waste to zero and with significant savings in energy and packaging needed with no need to spend time cooking or knowing how to do it. Following the lean startup model, we introduced a model for B2B customers that allow them to create dishes, decorations, customizations, suitable for hospitals, restaurants, bakeries, etc. In order to get our product to the home kitchens, users have requested two main features that go far beyond 3D printing technology. The two systems are a new cooking technology that uses just a fraction of the energy used by traditional ovens and microwave ovens and a prefilled capsule system. Both systems working together will convert our new device in an optimised sustainable mini food processing plant at home. The cooking system provides a very granular control of the temperature of the food being cooked, allowing to preserve the nutritional properties of the ingredients and cook according to the user tastes. This system can work also as a standalone device, which opens also new OEM and licensing opportunities for our company. It provides also a safer operation, as no element in the device will be heated to a point of causing harm, as compared to an oven. From a business perspective, reaching the mass market (home kitchens) will allow us to more tan double current revenue forecasts according to initial interest in USA, Europe and Asia, and to introduce new business models, like capsule licensing that will generate new revenue sources. We expect the feasibility study to provide us with a better market insight and a complete business plan for bringing our device to the market.

Keywords: connected appliance,healthier food,ineternet of things
Metabolic regulation of mitochondrial morphology (Mitomorphosis)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: France
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-04-01
End date: 2022-11-30
Duration (months): 68.0
Total project cost (EUR): 1375000.0
EU funding (EUR): 1375000.0
Participants: 1
Project status: CLOSED

The need for mitochondria in the body is ubiquitous yet the shapes these organelles take vary widely across tissues and change rapidly in response to nutrient availability. How and why this occurs is not well understood. Therefore, we propose an interdisciplinary research program that will investigate the molecular basis and metabolic regulation of mitochondrial morphology. Mitochondrial morphology is defined by opposing events of fission and fusion, which must be tightly controlled. We discovered that accelerated mitochondrial fission impairs cardiac metabolism and causes heart failure in mice, revealing an intriguing link between mitochondrial dynamics and metabolism. Seeking to understand how metabolic signals drive mitochondrial fission, we will characterize the inner membrane protein MTP18, whose fission activity is controlled by the PI3K nutrient-signalling pathway. First, we will define the interactome of MTP18 to discover the molecular components of the inner membrane fission machinery. Second, we will investigate the how mitochondrial fission is regulated by PI3K nutrient-signalling pathway the heart, liver, and kidney. We will determine whether cardiac dysfunction, liver cancer, and kidney failure caused by over-active PI3K signalling in the mouse can be rescued by blunting the downstream activity of MTP18 and re-balancing mitochondrial dynamics. Third, we will determine the disease relevance of mitochondrial fission in humans. For the first time, mitochondrial morphology from patient-derived cells will be evaluated in automated, high content screens to identify human mutations that drive imbalanced mitochondrial dynamics in a truly unbiased manner. Genome-wide RNAi screens in these cells will reveal novel modulators of mitochondrial dynamics. Taken together, this work aims to understand the metabolic pathways that control mitochondrial morphology and to develop a new technology to identify yet unknown modulators of mitochondrial dynamics.

Keywords: mitochondrial dynamics,metabolism
Following Protein Diffusion in Photosynthetic Membranes with Super Resolution (MeaSuRe)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-14
End date: 2017-10-23
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

The regulated diffusion of light-harvesting complexes in photosynthetic membranes is essential for photosynthesis, for instance for the redistribution of light-harvesting complexes between Photosystems I and II. To date, however, little is understood about the mobility of these proteins through the highly crowded membrane environment. In contrast to the huge amount of structural research that has been performed on biomolecules in the past, research on the dynamics is lagging far behind. The major limitation is the fact that the nanometer size regime of biomolecules is not accessible by classical optical techniques owing to the diffraction limit of light. To overcome this problem, we propose to use plasmonic nanoantennas, which are able to confine light at the nanoscale. In combination with Fluorescence Correlation Spectroscopy (FCS) this will allow measuring protein mobility in photosynthetic membranes with high, tens of nanometers, resolution. Directional and functional protein movement will be induced by illumination of the chloroplasts using specific light conditions; simultaneously following the protein movement will give new insights in how plants optimize their light harvesting capacity under fluctuating light conditions. The new nanoantenna-FCS based method, which we will develop to measure the diffusion of membrane proteins with nanometer resolution, has the potential to become widely used for nanobioimaging and ultrasensitive biosensing. This research will be performed by Dr. E Wientjes in the Laboratory of Biophysics of Wageningen University led by photosynthesis expert Prof. H van Amerongen. A long-term collaboration will be started with Wientjes current supervisor Prof. NF van Hulst and Prof. MF Garcia-Parajo from the Institute of Photonic Sciences in Barcelona who are leading scientists in nanophotonics. The outcome of this project will provide biophysicists with a new method to study membrane protein dynamics with super resolution.

Keywords: photosynthesis,membrane,fluorescence correlation spectroscopy,nanoantenna,plasmonics,diffusion