Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Up-scaling, demonstration and first market application of Hydrokemos’ patented technology as the most eco-efficient and cost-effective solution for nitrate polluted water treatment (WATIFY)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Spain
Call: Boosting the potential of small businesses for eco-innovation and a sustainable supply of raw materials (H2020-SMEINST-2-2015, 2015)
Start date: 2015-12-01
End date: 2018-01-31
Duration (months): 26.0
Total project cost (EUR): 1318660.0
EU funding (EUR): 923062.0
Participants: 2
Project status: CLOSED

Hydrokemos, a high tech Spanish SME, aims to demonstrate and commercialise the first fully clean equipment to purify nitrate polluted water. In the EU +20% of groundwater is contaminated by nitrates due to the use of fertilizers that have been and still are extensively applied in agriculture. On the other hand, demand for freshwater is increasing by 64 billion cubic meters every year. Groundwater is essential for meeting this increasing demand and existing solutions to purify it are highly inefficient and/or produce dangerous residues. Electrodenitrification (technology developed and patented by Hydrokemos) is the first fully clean technology that destroys nitrates dissolved in water transforming them into air (no waste is produced) and generates energy that is re-inserted into the system making it extremely energy-efficient. The objective of this project is to demonstrate – at full scale and in real market applications – the technical and commercial excellence of Hydrokemos’ unique technology. During the project, Hydrokemos will up-scale the existing prototypes building 4 full-scale prototypes to demonstrate its economic and technological performance across a range of typical industrial applications. These applications are: - Freshwater supply to food or metal industries; - Water purification for re-injection to public network; - Remediation of high nitrate waste-waters (metal industry and similar); - Prevent eutrophication; Hydrokemos will then operate these full-scale prototypes in real operational conditions demonstrating that electrodenitrification achieves much better performance than any other available solution (at least -50% reduction in investment and +20% in performance). Finally, business success means €38m incomes in year 5 with IRR 93% and NPV 7.523.711 € for Hydrokemos and generating also a very profitable business for its commercial stakeholders (NPV 16.415.453 € in 2022 for commercial distributors).

Keywords: nitrates pollution,water purification,wastewater remediation,fully clean technology,eco efficient
European Training Network to improve materials for high-performance, low-cost next- generation redox-flow batteries (FlowCamp)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Germany,Israel,Germany,Italy,Germany,Switzerland,Switzerland,Hungary,Hungary,France,France,Czechia,Netherlands,Netherlands,United Kingdom,Luxembourg
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2017-09-01
End date: 2022-02-28
Duration (months): 54.0
Total project cost (EUR): 3796578.23
EU funding (EUR): 3796578.23
Participants: 20
Project status: CLOSED

Renewable energy sources like wind turbines require large-scale, stationary energy storage systems to balance out fluctuations in energy generation. FlowCamp will advance the development of one of the most promising storage systems: redox-flow batteries (RFBs). The recruited fellows will develop materials (membranes, electrodes, electrolytes, catalysts, sealing materials) and macrohomogeneous models for three next generation RFBs (hydrogen-bromine, organic and zinc-air systems). They will then upscale the new systems to prototype level (TRL4/5), and validate them using the cutting-edge battery testing facilities available for the prestigious German-funded RedoxWind project at Fraunhofer ICT. The new RFB technologies can be combined in energy storage systems tailored to a wide variety of application scenarios, with lower cost, longer service life and higher efficiency than conventional (e.g. Li-ion) storage devices. Through FlowCamp, 15 ESRs will gain a unique skill-set comprising electrochemistry, material science and cell design/ engineering, as well as an overview of different RFB technologies and their implementation at prototype level. FlowCamp will consequently go far beyond existing electrochemical training, in a field with a high and growing research demand. The employability of the ESRs will be further enhanced by high-quality individualized training in scientific and complementary skills, and a structured network program of training units moving them from theoretical investigations towards industrial application and entrepreneurship. The active involvement of industrial partners, secondments in applied research and industry and a strong research and training emphasis on market requirements will furthermore provide them with the intersectoral experience needed for a career in electrochemical energy storage.

Keywords: redox flow batteries,hydrogen bromine,organic redox flow battery,zinc air battery,energy storage systems,novel membranes,sealing materials for redox flow batteries,modelling,simulation
Novel Release-on-demand micronutrient fertilisers for crops (MicroFert)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-08-01
End date: 2017-07-31
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

In many important agricultural crops successful fertilisation with micronutrients can lead to substantial increases in diseases resistance, marketable yield, and improved nutritional quality of food and feed. However, the plant availability of supplied micronutrients is usually too low due to the high reactivity of fertilisers under unfavourable soil conditions. Recently novel concepts for designing fertilisers have been adopted which try to extend their time of availability in the soil in different ways. This proposal, introduces the release-on-demand concept in which the plants themselves trigger the release of nutrients from nanoparticles at the time in their growth cycle that they need them. Layered Double Hydroxides (LDHs) are currently being developed in the host institution and are interesting candidates for the controlled release of micronutrients. LDHs consist of alternating layers of positively charged metal hydroxides and interlayers of anions so they can include both di and trivalent metal cations and different interlayer anions. The nutrient release is expected to be dependent on rhizosphere acidification via root excretion of protons, low molecular organic acids and CO2. The overall objective is to evaluate the potential of LDHs as release-on-demand micronutrient fertilisers, mainly focusing on Zn, Mn and Cu, and their interactions with N, P or K under a range of soil conditions and growing conditions. Experiments will cover both improving commonly used techniques and novel methods and designs leading to the formulation of patents, the development of novel fertilisers and crop production of increased yield and quality. The applicant has a very strong background in the characterisation of micronutrient fertilisers acquired during her PhD and postdoc experience that, together with the experience and facilities of the host and partners, will lead to the successful completion of the project and to the strengthening the career development of the researcher.

Keywords: micronutrients,fertilisation,release on demand,root activity,soil,chemistry,characterisation,plant
Development of “smart” amplifiers of reactive oxygen species specific to aberrant polymorphonuclear neutrophils for treatment of inflammatory and autoimmune diseases, cancer and myeloablation. (NeutroCure)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Ukraine,Germany,Germany,Spain,Sweden,Sweden,France,France,United Kingdom,United Kingdom
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2019)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 2999998.75
EU funding (EUR): 2999998.75
Participants: 12
Project status: SIGNED

Reactive oxygen species (ROS) have key functions in healthy organism such as redox signaling for regulation of cell growth, triggering formation of neutrophil extracellular traps (NETs), and modulation of inflammation. Since in high concentration ROS are damaging to tissues, nature has evolved precise mechanisms to control their generation at the required time, concentration and space, proximal to their target. Disturbance of these mechanisms leads to aberrant ROS production that causes uncontrolled inflammation, occurs in myeloablation caused by radio- or chemotherapy and is a crucial feature of cancer cell phenotype as well as autoimmunity. Despite the damaging properties of ROS it is a paradox that pharmaceutical ROS amplifiers can reverse (“cure”) many pathologic features. For example, ROS-induced cancer cell killing inhibits cancer growth, ROS-induced deactivation of T-cells and NETs generation contributes to resolution of inflammation, and ROS-induced boosting of haematopoiesis can relieve myeloablation. These exciting possibilities have not been realized in clinical settings yet, since the high level of temporal and spatial control of ROS generation, required to allow for safe patient treatment, has yet not been achieved for any known drug. NeutroCure will be the first attempt to achieve a breakthrough solution to this problem. Using an innovative approach based on the multiple-trigger prodrug activation, this consortium will develop safe ROS amplifiers capable of boosting ROS specifically in abnormal polymorphonuclear neutrophils associated with cancer, uncontrolled inflammation and relevant for myeloablation without affecting normal cells. NeutroCure consists of 6 European academic partners and an SME who will promote commercialization of the new drugs. We expect that this project will have a great positive impact on the Society by providing previously unexplored treatment solutions for severe pathological conditions caused by dysregulated ROS-production.

Keywords: reactive oxygen species,neutrophils,autoimmunity,inflammation,cancer
Molecular Diagnostics Through DNA Modification and Interfacial Engineering (DNASURF)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Action type: Marie Skłodowska-Curie actions
Countries involved: United Kingdom
Call: MSCA Special Needs Allowance (H2020-IBA-MSCA-SNLS-2020, 2020)
Start date: 2020-05-01
End date: 2023-05-31
Duration (months): 37.0
Total project cost (EUR): 22500.0
EU funding (EUR): 22500.0
Participants: 1
Project status: SIGNED

Request for financial support to cover the additional costs that researchers/staff members with disabilities face due to the increased costs of their mobility and/or to ensure necessary assistance by third persons or for adapting their work environment.
Probing our Galaxy from the Center to the outskirts (VEGA_P)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1999827.0
EU funding (EUR): 1999827.0
Participants: 1
Project status: SIGNED

Supermassive black holes — located in galactic nuclei— and dark matter —dominant in galactic halos— are vital ingredients in the cosmological process of galaxy formation, including that of our own Galaxy. However, probing our Galactic Centre (GC) and halo has proven observationally challenging. Hypervelocity stars (HVSs) are unique in that they deliver key information on both. Following interactions with black holes in the vicinity of Sagittarius A*, HVSs are ejected on fast trajectories through the halo. They thus bear testimony not only to the black hole and stellar populations within the hard-to-access innermost parsec, but also to the Galactic mass distribution, imprinted on their orbits. Exploiting HVSs, however, has been limited by the paucity and quality of data. The ESA Gaia mission and new spectroscopic surveys are about to dramatically change this. Their upcoming data releases contain a few hundred HVSs with unprecedented astrometric measurements, but identifying them requires careful analysis of the basic data. This proposal capitalises on my comprehensive theoretical, observational and data mining work on SDSS and previous Gaia data. The proposal unprecedentedly combines three key facets: i) identifying and characterising HVSs; ii) modelling HVS data in a full statistical framework and theoretically interpreting our results for the GC; and iii) performing a joint analysis with complementary Galactic halo probes, never observed so abundantly before Gaia. The project will yield i) ~hundred of GC stars in a complementary mass range and with more robust parameter estimation than from direct GC observations; ii) the population of black holes in the GC and their dynamics; iii) robust ~10% precision measurements of the Galaxy mass distribution. These will allow not only to discriminate between assembly scenarios for both the Milky Way and its GC, but also to uniquely calibrate rate estimates for galactic nuclear phenomena, including gravitational wave sources.

Keywords: galactic nuclei dynamics,tidal disruption events,gravitational wave sources
Augmented Reality Assisted System for Utilities Infrastructure Management (AIM)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Portugal
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-03-01
End date: 2018-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The installation, upgrade and operational maintenance of utility infrastructures protection is a global challenge which is continuously growing. The Augmented Reality Assisted System for Utilities Infrastructure Management(AIM) is a system designed to support utility field workers. The AIM platform integrates different technologies such as: positioning and sensors(GNSS), Augmented Reality(AR), Geographical Information Systems(GIS) and 3D databases. In practise, this system will guide the field workers in underground and building utilities to ‘see’ what is happening under the ground, floor and behind the walls, like an “x-ray image” of the infrastructure. The system is using AR interfaces to render the complex 3D models of the utilities infrastructure such as water, gas, electricity and communications. in an approach that is easily understandable and useful during field work. AIM will provide better, more streamlined on-site utility management; maximize existing investments; reduce operation and management costs; reduce accidents and improve working conditions. AIM’s target customers are all organizations involved in the utilities management sector. This project goal is to develop a technical and commercial feasibility assessment as a milestone step towards the creation of the AIM’s line of products and services and it’s worldwide commercialization. The objectives of this feasibility assessment are to define market niches, consumer needs, evaluate relevant legislation aspects, identify and solve market barriers, determine the AIM’s technical feasibility, as well the economic and social impact of it’s commercialization. The project will create a return on investment of 192% in 5 years of commercialization, grow the company sustainability and generate the conditions to hire 60+ staff. Most importantly it will contribute to improve the European utility infrastructure management while simultaneously reducing it’s financial and societal costs.

Keywords: augmented reality utilities infrastructure management gnss gis
Linking Human Mobility and Marine Megafauna Movement in the Mediterranean Sea for a better integration of Blue Growth (MOVEMED)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-01
End date: 2020-12-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

This proposal will investigate the dynamics and links between human mobility and marine megafauna movement using a computationally intensive data-driven approach. I will analyse the effects of marine environment and cumulative human pressures on marine megafauna using electronic monitoring systems and earth observations, which now allow an unprecedented opportunity to simultaneously monitor marine animal movement, ship-based activities and the marine environment. I will direct the research through a multidisciplinary approach, combining state-of-the-art quantitative methods and computational tools from movement ecology, oceanography and marine spatial planning. I will demonstrate this approach in the Mediterranean Sea, a hotspot for marine megafauna under pressure from multiple human influences. The region can serve as a miniature ocean to investigate climate-driven effects and explore the potential application of dynamic conservation measures in trans-boundary areas. Results will allow the linking of key enabling ocean observation technologies to their application in assessing the potential impacts from anthropogenic activities and promoting the sustainable development of maritime industries. This is a matter of enormous concern for Europe, since our results will provide the scientific basis to establish future conservation actions within the framework of Integrated Maritime Policy. This proposal marries skills and expertise that maximizes the chances of the project’s success. The host lab, supervised by Prof Godley, has a long history of research in marine movement ecology, particularly those associated with marine vertebrates and conservation research. The candidate, Dr March, is an expert in marine spatial ecology and ocean observing systems. The combined skill-set will allow the team to address fundamental, timely and important questions about animal ecology and conservation.

Keywords: marine megafauna,movement ecology,marine spatial planning,cumulative impact mapping,ocean observing systems,mediterranean sea,big data,species distribution modelling
Targeting the cancer stem cell (CSC) metabolism with designed, reactive metal complexes (antiCSC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Spain,Spain
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2021-01-01
End date: 2022-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 130000.0
Participants: 3
Project status: CLOSED

Designed, bulky metal complexes with a labile coordination position react with accessible guanines at G4 DNA quadruplexes, promoting changes in their conformation and function. Importantly, we have found that this selective reactivity leads to very interesting biological effects. In particular, some of these compounds are able to suppress the “stem”-like character of cancer stem cells, apparently by deterring their mitochondrial respiration. Preliminary experiments, including in vivo assays, confirm that these biological effects result in remarkable antitumoral activities. This proposal aims to explore the scope of the approach, confirm that the mechanism of action involves mitochondria, design more selective versions and exploit the potential of the compounds as new type of anticancer agents.

Keywords: synthetic metal complexes,ruthenium,coordination chemistry,anticancer chemotherapy,cancer stem cells,chemical biology,biomedicine