Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
NEw generation MEthods for numerical SImulationS (NEMESIS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: France,Italy
Call: ERC Synergy Grants (ERC-2023-SyG, 2023)
Start date: 2024-01-01
End date: 2029-12-31
Duration (months): 72.0
Total project cost (EUR): 7818782.0
EU funding (EUR): 7818782.0
Participants: 4
Project status: SIGNED

Relevant partial differential equations (PDEs) problems of the 21st century, including those encountered in magnetohydrodynamics and geological flows, involve severe difficulties linked to: the presence of incomplete differential operators related to Hilbert complexes; nonlinear and hybrid-dimensional physical behaviors; embedded/moving interfaces. The goal of the NEMESIS project is to lay the groundwork for a novel generation of numerical simulators tackling all of the above difficulties at once. This will require the combination of skills and knowledge resulting from the synergy of the PIs, covering distinct and extremely technical fields of mathematics: numerical analysis, analysis of nonlinear PDEs, and scientific computing. The research program is structured into four tightly interconnected clusters, whose goals are: the development of Polytopal Exterior Calculus (PEC), a general theory of discrete Hilbert complexes on polytopal meshes; the design of innovative strategies to boost efficiency, embedded into a general abstract Multilevel Solvers Convergence Framework (MSCF); the extension of the above tools to challenging nonlinear and hybrid-dimensional problems through Discrete Functional Analysis (DFA) tools; the demonstration through proof-of-concept applications in magnetohydrodynamics (e.g., nuclear reactor models or aluminum smelting) and geological flows (e.g., flows of gas/liquid mixtures in underground reservoirs with fractures, as occurring in CO2 storage). This project will bring key advances in numerical analysis through the introduction of entirely novel paradigms such as the PEC and DFA, and in scientific computing through MSCF. The novel mathematical tools developed in the project will break long-standing barriers in engineering and applied sciences, and will be implemented in a practitioner-oriented open-source library that will boost design and prediction capabilities in these fields.

Keywords: finite element methods,error analysis,finite element exterior calculus,hilbert complexes,efficient algebraic solvers,nonlinear pdes,magnetohydrodynamics,porous media flows,fluid structure interaction,virtual element methods,hybrid high order methods
The Scale Revolution in Physics: Historical and Philosophical Perspectives (RESCALE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-04-01
End date: 2030-03-31
Duration (months): 60.0
Total project cost (EUR): 1455058.0
EU funding (EUR): 1455058.0
Participants: 1
Project status: SIGNED

The ideal of a final theory has shaped much of modern physics and its philosophical interpretations. Physicists have used it as a blueprint to construct theories of space, time, matter, and motion that apply in principle everywhere and under any circumstances. Philosophers have used it as a guide to interpret existing theories and depict the entire universe in terms of a bedrock of fundamental entities. Although this ideal still plays an important role today in quantum gravity, the situation has considerably changed since the 1950s. Physicists now widely recognize that our best current theories work only at certain scales, and that this may well be the case for any future empirically successful theory. Physicists also spend most of their time studying systems scale by scale and analyzing how physical effects depend on each other across scales, even in the context of quantum gravity. How should philosophers adjust their interpretative practice if they are to take this new way of doing physics seriously? What kind of world picture would result from this? The RESCALE project contends that the ideal of a final theory no longer provides a sensible interpretative guide, leaving us with no better option but to depict the universe one scale at a time. More precisely, the project will show through an in-depth integrated historical and philosophical study that physicists’ new scale-based theoretical practice leads us to draw a partial picture of the world structured in a complex hierarchy of overlapping layers across scales, which is largely independent of what may lie beyond. Besides disclosing a fundamental epistemological transformation in the recent history of science and showing how it forces us to rescale our world picture, this systematic interdisciplinary study at the crossroads of history, philosophy, and physics will have profound implications for our understanding of representation, reduction, realism, and metaphysics at the frontiers of science.

Keywords: history and philosophy of physics effective field theories renormalization group scientific representation reduction and emergence scientific realism metaphysics of science
Oceanic Physics-based Parameterizations of Internal Wave-driven Mixing (OPPIWaM)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-07-01
End date: 2031-06-30
Duration (months): 60.0
Total project cost (EUR): 1480000.0
EU funding (EUR): 1480000.0
Participants: 1
Project status: SIGNED

Oceanic Physics-based Parameterizations of Internal Wave-driven Mixing (OPPIWaM) tackles one of the most pressing open problems in physical oceanography: how energy cascades toward the small scales to fuel turbulent mixing, one of the main drivers of the large-scale overturning circulation with huge impacts on the Earth’s climate. Mixing scales are below the resolution of ocean circulation models, and the current parameterizations are static and empirical, resulting in high uncertainty in model outputs. Internal waves (IWs) represent the crucial conduit of energy from the large-scale forcings, such as winds or tides, down to the mixing scales. A grand challenge to upgrade the models’ quality is to leverage the physical properties of this IW interscale energy hub to reach a quantitative understanding of mixing based on the ocean’s equations instead of on empirical numbers. To do so, OPPIWaM sets up an unprecedented multilevel investigation of the physics of IW-driven mixing, with three main objectives: 1. Develop a first-principle solver for the IW interscale dynamics; 2. Develop reduced-model dynamical approximations to provide interpretation as opposed to a black-box package; 3. Constrain the first-principle and reduced-model dynamics with high-resolution field studies and global observational datasets. Finally, OPPIWaM’s findings will integrate into a dynamical first-principle component ready for implementation in the models. The groundbreaking approach to achieve the objectives hinges upon concurring revolutions in theory (wave turbulence recent breakthroughs), (clustering and equation learning) algorithmic efficiency and availability, and (Argo-led) ocean-observation paradigm change. High stakes for climate and cutting-edge theoretical, numerical and observational challenges make OPPIWaM’s objectives ambitious. Right timing and PI’s key experience and positioning within nonlinear waves and ocean mixing communities make OPPIWaM’s ambitious objectives achievable.

Keywords: ocean mixing,oceanic internal waves,wave wave interactions,wave turbulence,internal tides,finescale parameterization
Future-proofing Heritage Buildings by Optimising Comfort and Energy in Time and Space (HeriTACE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Efficient, sustainable and inclusive energy use
Action type: Research and Innovation actions
Countries involved: Belgium,Estonia,Norway,Italy,France,Finland
Call: Future-proofing historical buildings for the clean energy transition (HORIZON-CL5-2023-D4-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 4499501.25
EU funding (EUR): 4499501.25
Participants: 17
Project status: SIGNED

The HeriTACE project brings together a transdisciplinary team of research institutes, authorities, SMEs, and industry experienced in design, technology, and policymaking in the domains of conservation, buildings and energy. A significant increase in deep renovations of heritage buildings has the potential to lead to effective energy demand reductions and readiness for the transition to R2ES. Based on prior research and field knowledge supported by various EU and national projects, bottlenecks have been identified that prevent the futureproofing of heritage buildings and its replication. To overcome them, HeriTACE proposes innovative technical solutions, integrated into a holistic and multi-scale renovation approach, by developing and validating: (1) A replicable holistic assessment model and standardised processes to create a holistic vision and plan on the renovation requirements for heritage townhouses in historical neighbourhoods, (2) Optimal and integrated design approaches for the deep renovation of heritage townhouses, with well-considered, targeted and minimal invasive renovation measures, (3) Durable insulation and air tightness solutions for the renovation of building envelopes, respecting their heritage values and traditional building technology, (4) Optimised and smart controlled HVAC-concepts adapted to heritage townhouses, optimising comfort, and indoor air quality precisely where and when the building users need it, and (5) Integrated R²ES-based energy supply solutions, maximising the share of local R²ES in heritage buildings within historical neighbourhoods. The project will deliver solutions for authorities and designers to envision and govern a sustainable energy future for heritage townhouses in historical neighbourhoods, thus putting the EU Green Deal and New European Bauhaus into practice. Close collaboration between researchers, SMEs and industry shall increase the availability of high-quality solutions for the building conservation sector.

Keywords: heritage buildings,renewable energy sources,hvac,mpc,insulation systems
SATGENO: Regenerative gene repair therapy for muscular dystrophies (Satgeno)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2025-06-01
End date: 2027-11-30
Duration (months): 30.0
Total project cost (EUR): 3571427.14
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Muscular dystrophies (MDs) are a group of about 50 different monogenic disorders characterized by progressive, irreversible muscle wasting, leading to loss of autonomy and premature death. Patients rely on palliative care; the disease burden is immense. Current gene therapy approaches do not address the underlying genetic causes. The challenges to develop gene therapies for MDs include the genetic variability and the lack of a safe drug delivery methods to muscle. MyoPax is a clinic-ready company focused on restoring muscle function in patients with muscle diseases via targeted regenerative therapies. For genetic MDs we have developed the Satgeno platform: We aim to harness the body’s natural regenerative capabilities to sustainably deliver a gene repair therapy for the first time to muscle. Satgeno leverages our patented stem cell technology to manufacture highly regenerative muscle stem (“satellite”) cells called Primary Human Satellite cells-derived muscle stem cells (PHSats). PHSats rebuild muscle tissue and, very importantly, generate new muscle stem cells in their respective niche. This capability allows us to 1) correct MD-causing mutations ex vivo in PHSats using virus-free, mRNA-mediated, CRISPR-derived gene editing, 2) deliver gene-corrected healthy stem cells to functionally important muscles in MD patients, and 3) sustainably rebuild healthy muscle function. With EIC support, we will conduct the first-in-human DELI550 trial, focusing on a frequent founder mutation. Pending safety and efficacy validation, we expand our approach into a comprehensive platform to treat various MD mutations affecting 400K+ people in the EU and US. This trial will mark a breakthrough. The platform has the potential to transform the patient´s treatment as acknowledged by Nature medicine “11 Clinical Trials that Will Shape Medicine in 2023”. We strive for a future where individuals with MDs experience significantly improved quality of life and functional independence.

Keywords: muscular dystrophy,crispr,orphan drug,limb girdle muscular dystrophy,satellite cells,advanced therapy medicinal products atmps
Intelligent and Sustainable Building Management powered by Cross-Sectoral Lifecycle (DATAWiSE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Efficient, sustainable and inclusive energy use
Action type: Innovation actions
Partnership: B4P (co-programmed)
Countries involved: Greece,Spain,Italy,Austria,Latvia,Netherlands,Serbia
Call: Innovative uses of lifecycle data for the management of buildings and buildings portfolios (Built4People Partnership) (HORIZON-CL5-2023-D4-02, 2023)
Start date: 2024-06-01
End date: 2027-08-31
Duration (months): 39.0
Total project cost (EUR): 5561649.78
EU funding (EUR): 4991148.55
Participants: 16
Project status: SIGNED

DATAWiSE will develop and test building and building portfolio management tools, leveraging cross-sectoral lifecycle data on the basis of an open, secure, interoperable, and scalable framework. Utilizing cutting-edge artificial intelligence and advanced analytics, the methodology will integrate data from a variety of sources to provide a holistic understanding of building operations. DATAWiSE will design and implement a scalable data architecture that ensures data quality, privacy, interoperability, and sharing, and a Data Sharing Platform that will not only ensure interoperability and scalability but will also prioritize data sovereignty to secure data handling and preserve ownership control. DATAWiSE will develop: i) a Data-driven Building Performance Management (DBPM) toolkit which will harness Building Information Modeling (BIM) data in conjunction with advanced data mining techniques through a digital twin. ii) An AI-enhanced Lifecycle Data-driven Decision Support (LD2S) toolkit. This will serve as a versatile solution for well-informed decision-making across planning, renovation, and sustainability domains. Through these tools, the project will offer a suite of added-value services aimed at optimizing building management in various aspects: Electrical and Thermal Flexibility Management; AI-Powered Energy Forecasting and Optimization; Smart Sustainability & Comfort Balancing for Building Occupants; Adaptive Building Risk & Resilience Assessment; Circular Lifecycle Assessment; Predictive Maintenance; Integrated Sustainability Performance Management; Smart Readiness Assessment. Besides technological innovation, the project also incorporates a supportive market and policy framework designed to offer evidence-based pathways for widespread adoption and commercialization.

Keywords: lifecycle data,big data,building management,energy performance,environmental performance,renovation,risk assessment,investment planning,digitalization,monitoring,interoperability
Free Speech Voice-Assisted Arrhythmia Monitoring (FS-VAAM)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 60.0
Total project cost (EUR): 2225000.0
EU funding (EUR): 2225000.0
Participants: 1
Project status: SIGNED

The Cardiokol solution VAAM (Voice-Assisted Arrhythmia Monitoring) is a novel software platform that enables automatic, passive and low-cost monitoring/screening of large populations at-risk for scaling up prevention of strokes and acute events due to AF. Our existing solution is the only clinically proven vocal based indicator for detecting and monitoring AF (Atrial Fibrillation). We offer Revolutionary affordable, scalable, long-term and age-friendly free speech-based monitoring solution. It is applicable for mass at-risk populations, mainly older adults (65+) by utilizing proprietary technology that is implemented in speech platforms such as landlines, smartphones and voice assistants. Our long-term strategic offering is a unique solution which allows for the first time wide scale prevention of multiple conditions, starting with early detection of AF to support prevention of its acute complications (stroke, cardiac complications etc.) and later detection of other Arrhythmias, Heart & Acute Chronic diseases. Cardiokol innovative approach combines free speech signal processing, analytics and AI tools with proprietary algorithms for the analysis of vocal signals. We have developed and validated test protocols for the detection and monitoring of AF (Atrial Fibrillation) including silent burdens. Cardiokol’s technology extracts and identifies vocal parameters associated with AF (extraction of 200 features out of 7,000). We offer significantly improved management of AF for clinicians and healthcare providers improving detection yields and disease management for un-diagnosed and diagnosed patients.

Keywords: voice assisted arrhythmia monitoring,atrial fibrillation remote monitoring,digital services,health related biotechnology,mass screening,atrial fibrillation,vocal biomarkers,stroke prevention
SINGLE-GRAIN RE-ENGINEERED ND-FE-B PERMANENT MAGNETS (GREENE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Slovenia,Germany,Austria,Spain,Netherlands,Italy,Ukraine,France
Call: Advanced materials for magnets in applications for the New Energies Market (RIA) (HORIZON-CL4-2023-RESILIENCE-01-TWO-STAGE, 2023)
Start date: 2024-06-01
End date: 2028-05-31
Duration (months): 48.0
Total project cost (EUR): 7999972.5
EU funding (EUR): 7999972.5
Participants: 15
Project status: SIGNED

GREENE addresses one of the Europe’s Grand Societal Challenges, aligned with the European Green Deal and the recently released Green Deal Industrial Plan for the Net-Zero Age, which alongside the Circular Economy Action Plan, sets the framework for the transformation of the EU’s industry. Rare-earth-element (REE) permanent magnets based on Nd–Fe–B are vital for use in electric vehicles and wind turbines, making then central to Europe’s green-energy future. These magnets have outstanding properties, but they are not without their weaknesses. There is, of course, the well-known dependence on imports from China, on which Europe is presently totally dependent. However, here, in line with the scope of the Resilient valu chains 2023 call, GREENE will focous on a redesign of Nd-Fe-B magnets as an advanced material where the Nd in the grain boundary is replaced. At the same time, we will address the problem of translating the under-used intrinsic properties of the hard-magnetic Nd2Fe14B phase into better extrinsic properties of the magnet. And, since the process will apply equally well to fresh or recycled feedstocks, we will also be impacting on the problem of supply dependence.

Keywords: rare earth based permanent magnets,nd fe b,redesign and engineering in situ,grain boundaries,recycling
Exploring Ephemeral Feminisms on Portuguese Instagram (EPH-FEM-PI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Portugal
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2025-03-31
Duration (months): 31.0
Total project cost (EUR): 172618.56
EU funding (EUR): 172618.56
Participants: 1
Project status: CLOSED

Social media platforms, like Instagram, allow for a wide range of people – including those outside traditional activist circles – to create or engage with feminist content within quotidian social media practices, with political content co-existing with personal, mundane, or aesthetically-oriented content. This project will explore how online feminist practices take shape in increasingly popular yet under-researched practices of ephemeral social media by focusing on Instagram Stories, exploring the new dynamics these carry. This project explores the under-studied local context of Portugal. Portugal is experiencing a moment of political polarisation, which is reflected in its social media landscape. Feminist and political discourses are common on Instagram yet often met with backlash from conservative or right-wing voices. This is a rich and novel site for the analysis of these dynamics, revealing local particularities that are absent from Anglo-Saxon contexts. This project addresses three research objectives: analyse how feminisms are expressed through ephemeral social media affordances; explore what conventions and concerns underly the creation of feminist content; and examine how audiences engage with feminisms on Instagram. This project proposes an innovative ethics-driven, multi-methodological approach. It combines qualitative strategies with the use of digital tools for an exploratory analysis of feminist Instagram Stories; in-depth interviews with feminist content-creators; and focus groups with social media users who engage with feminist content on Instagram.

Keywords: instagram online feminism ephemeral media portugal multi methods