Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Sustainable Data Lakes for Extreme-Scale Analytics (SmartDataLake)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Austria,Germany,Switzerland,Greece,Netherlands
Call: Big Data technologies and extreme-scale analytics (H2020-ICT-2018-2, 2018)
Start date: 2019-01-01
End date: 2021-12-31
Duration (months): 36.0
Total project cost (EUR): 3945450.0
EU funding (EUR): 3945450.0
Participants: 8
Project status: CLOSED

Data lakes are raw data ecosystems, where large amounts of diverse data are retained and coexist. They facilitate self-service analytics for flexible, fast, ad hoc decision making. SmartDataLake enables extreme-scale analytics over sustainable big data lakes. It provides an adaptive, scalable and elastic data lake management system that offers: (a) data virtualization for abstracting and optimizing access and queries over heterogeneous data, (b) data synopses for approximate query answering and analytics to enable interactive response times, and (c) automated placement of data in different storage tiers based on data characteristics and access patterns to reduce costs. The data lake’s contents are modelled and organised as a heterogeneous information network, containing multiple types of entities and relations. Efficient and scalable algorithms are provided for: (a) similarity search and exploration for discovering relevant information, (b) entity resolution and ranking for identifying and selecting important and representative entities across sources, (c) link prediction and clustering for unveiling hidden associations and patterns among entities, and (d) change detection and incremental update of analysis results to enable faster analysis of new data. Finally, interactive and scalable visual analytics are provided to include and empower the data scientist in the knowledge extraction loop. This includes functionalities for: (a) visually exploring and tuning the space of features, models and parameters, and (b) enabling large-scale visualizations of spatial, temporal and network data. The results of the project are evaluated in real-world use cases from the business intelligence domain, including scenarios for portfolio recommendation, production planning and pricing, and investment decision making. SmartDataLake will foster innovation and enable European SMEs to capitalize on the value of their own data lakes.

Keywords: distributed data management,approximate analytics,storage tiering,heterogeneous information networks,entity resolution,link prediction,clustering,visual analytics,business intelligence
Harnessing the power of Digital Social Platforms to shake up makers and manufacturing entrepreneurs towards a European Open Manufacturing ecosystem (OpenMaker)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Spain,Italy,Switzerland,Türkiye,Slovakia,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Collective Awareness Platforms for Sustainability and Social Innovation (H2020-ICT-2015, 2015)
Start date: 2016-06-20
End date: 2018-12-19
Duration (months): 30.0
Total project cost (EUR): 3289406.25
EU funding (EUR): 3156906.25
Participants: 11
Project status: CLOSED

OpenMaker brings together mainstream manufacturers and makers (i.e. tech-savvy craftsmen driven by social innovation and open source principles) in an purposely designed ecosystem built to enable cross-boundary partnerships for innovation. The partnerships will be facilitated by a targeted programme piloted in four locations in Europe and curated by experienced facilitators. Combining skills and expertise across boundaries will benefit all collaborators and stimulate innovation in manufacturing. Specifically, in relation to business models, production processes, products and governance structure and systems. This is intended to contribute to industrial renewal in Europe which will have direct benefits for sustained growth and employment. This bespoke ecosystem will blend on and offline opportunities for collaboration mirroring the multifaceted ways individuals interact in a networked society. Our dedicated digital platform will support communication between all the partners in the four locations and allow stakeholders and partners from other locations to participate. It will also function to map and collect data on social dynamics. Network analysis will be used to harvest data, and generate a deeper understanding of the social dynamics between the partners and across the stakeholders which constitute this community. Such knowledge will help the consortium to improve methods and tools to foster partnerships for innovation in manufacturing. This project will benefit society through generating novel partnerships that combine greater productivity and social impact. Moreover it will provide evidence for business, policymakers and the public that industrial development can serve the common good while still being competitive and sustainable.

Keywords: open manufacturing,business ecosystems,value driven innovation
Growth hormone: an endocrine factor that integrates thermogenic and circadian signals to regulate brown adipose tissue activity. (GRO-BAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-10-01
End date: 2018-09-30
Duration (months): 24.0
Total project cost (EUR): 212194.8
EU funding (EUR): 212194.8
Participants: 1
Project status: CLOSED

The twin pandemic of obesity and diabetes is one of the greatest health challenges we face today. While fat is at the center of the problem, it may also be part of the solution. It has recently been shown that humans have brown or brown-like fat, whose primary function is to burn, rather than store, energy. This energy-consuming capacity of brown and brown-like fat has the potential to be harnessed to treat obesity and diabetes. The host supervisor has recently discovered that brown adipose tissue (BAT) metabolism is not only controlled by classic thermogenic regulation, but also by the circadian rhythm of the body’s molecular clock. During my PhD training, I observed a doubling in the size of interscapular BAT in mice that lack growth hormone receptor (GHR). I found that BAT has some of the highest levels of Ghr out of all tissues in the body. Despite this, the role of GHR in BAT remains unknown. My preliminary data suggests that GHR is a critical mediator of both thermogenic and circadian regulation. We propose to use genetic gain- and loss-of-function studies accompanied by pharmacologic modulation of GHR to determine its role in BAT. Our in vitro and in vivo work will be complemented by human studies to measure the fuel uptake and thermogenic capacity of BAT. The outcome will be highly relevant to human disease given the enormous potential of BAT activation in the treatment of obesity and diabetes.

Keywords: growth hormone,brown adipose tissue,beige adipose,circadian rhythm,thermogenesis,energy expenditure,metabolism,growth hormone receptor,circadian
Human Genetic Basis of Severe Staphylococcal Infections in Childhood (HGB-StIC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands,United States
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-01
End date: 2021-12-31
Duration (months): 36.0
Total project cost (EUR): 260929.8
EU funding (EUR): 260929.8
Participants: 2
Project status: CLOSED

Staphylococcus aureus is one of the most important bacterial pathogens impacting human health. Beta-barrel pore-forming toxins (BB-PFTs) are major virulence factors of S. aureus that destroy phagocytes, key effectors of immunity during staphylococcal infection, in a receptor-specific manner. Acquired immunity to a specific compound of S. aureus, LTA, can rescue an inborn error of the TLR2 pathway (TIRAP deficiency). I hypothesize that severe staphylococcal infections during childhood, at least in some patients, can result from single gene inborn errors of immunity. Some of these disorders may affect immunity to BB-PFTs and the TLR2 pathway. In this project, a cohort of ±70 patients with severe S. aureus infections during childhood will be investigated for mutations responsible for a poor outcome of infection. I will perform whole exome sequencing in these patients and their parents. I will search for mutations in genes encoding BB-PFT-receptors and the TLR2 pathway. I will also search for mutations in a genome-wide approach, testing various genetic models and taking advantage, when appropriate, of genome-wide linkage. I will then functionally characterize the candidate mutations. Depending on the gene identified, a set of experiments will be performed to investigate the functional consequences of the morbid gene on immunity against S. aureus, and I will further characterize the specific host-pathogen interaction. This project will not only shed light on the pathogenesis of S. aureus, but will also provide the basis for new avenues of vaccine and treatment strategies. By investigating human host counterparts in a genome-wide setting, this study is the first unbiased and systematic assessment linking S. aureus virulence factors with host genetic predisposition.

Keywords: staphylococcus aureus,human genetics,genome wide approaches,infectious diseases,pediatrics
DiasporaLink (DiasporaLink)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Spain,Ireland,India,Ethiopia,Sweden,Sweden,Russian Federation,France,Netherlands,United States,Denmark,United Kingdom,United Kingdom,United Kingdom,Portugal,Canada,Chile,Morocco,Nigeria,Brazil,Denmark
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2015-02-01
End date: 2019-01-31
Duration (months): 48.0
Total project cost (EUR): 657000.0
EU funding (EUR): 571500.0
Participants: 27
Project status: CLOSED

DiasporaLink is a 4-year exchange program between 24 universities and research institutes representing EU, the Americas, Africa and Australia and will investigate, evaluate and facilitate transnational diaspora entrepreneurship, TDE as driver of development and wealth creation in countries of origin and residence. • The partners in DiasporaLink have together a unique possibility to have a substantial impact on a global, European and national level targeting different groups and stakeholders: • The international research community • Institutions and policy makers in the social, economic and development field • Diaspora organizations and communities • Media and press This is underlined by the specific network of the partners • GEM Global Entrepreneurship Monitor • IMISCOE International Migration, Integration, Social Cohesion • International Council for Small Businesses • Swedish TDE network Core tasks are: • Structure research on diaspora cross-border entrepreneurship in migration corridors • Create awareness among policy and decision makers of the potential of TDE through publications and a web-site • Build a IT-curricula for transnational entrepreneurship within and outside the universities • Build an ICT-platform for internal communication and for transnational team building The exchange of staff is built around research in common WP’s and around regular and touring workshops both internal and external. The objective is to create a global, extended university network with the mission to monitor the entrepreneurship in migration corridors, define obstacles and support the corridor stakeholders with information and tuition. Essential is close contacts with diaspora entrepreneurs and diaspora organizations are systematically approached through workshops and media, for involving diaspora organizations as active partners.

Keywords: diaspora,entrepreneurship,team building,international trade,trade for development
Hardware Acceleration for Computing on Encrypted Data (BELFORT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Belgium
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2022-03-01
End date: 2027-02-28
Duration (months): 60.0
Total project cost (EUR): 2425875.0
EU funding (EUR): 2425875.0
Participants: 1
Project status: SIGNED

Electronics are part of all aspects of our daily life, at home, at work, while on the road. Smart cities, medical devices, financial transactions, self-driving cars, all rely on electronics. At the same time, these activities generate huge amounts of data, which for privacy and security reasons, are stored encrypted on a possibly untrusted cloud server. Yet, many applications benefit from operations on this data. Statistics or machine learning on medical, financial, automotive or energy data could discover trends or abuse, could be used to monitor pandemics, to tune supply and demand, and much more. Ideally, the calculations on the data should be done without decrypting them first to avoid data leaks. Computing on encrypted data is the new magic in the field of cryptography: it enables calculations on the encrypted data, while data remains encrypted in the cloud and without the need to decrypt it. The result will only be decrypted by the final recipient. Challenging in these novel mathematical concepts is a gigantic blow-up in the size of ciphertext data, in the amount of calculations on the encrypted data, and in the novel lattice based arithmetic used. The core challenge addressed in BELFORT is to make this new technology feasible from a hardware perspective and in realistic scenarios, providing the best performance/energy balance, for it to run on cloud servers and edge devices, within reasonable memory, computation and energy budgets. We propose reconfigurable hardware-based acceleration with domain-specific programmable co-processors, which combine energy efficiency with domain specific programmability and with resistance to attacks from classic and quantum computers. We will develop multiple new ideas as well as bring them together in an end-to-end demonstrator. The PI has the unique expertise and is a pioneer in translating novel cryptographic algorithms into efficient and secure realizations on a wide range of hardware/software platforms.

Keywords: secure electronic circuits,digital hardware,fpga and asic,resistance to attacks,hardware security evaluation
Cultural Expertise in Europe: What is it useful for? (EURO-EXPERT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Italy,France,France,United Kingdom
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-10-01
End date: 2023-03-31
Duration (months): 78.0
Total project cost (EUR): 1562495.13
EU funding (EUR): 97864.88
Participants: 4
Project status: SIGNED

Respect for diversity has been at the forefront of political accession to the European Union since 1993 and socio-legal scholarship has developed articulated reflections on the accommodation of ethnic and religious minorities in Europe. Country-experts have been instructed with increasing frequency in judicial and pre-judicial proceedings involving members of diasporic communities. In some common law countries the role of the expert witness has expanded to systematically assist the judge when litigants or defendants belong to minorities; in most civil law countries, similar roles are played by translators and cultural mediators, including notaries and lawyers. Cultural expertise is sometimes used in order to avoid excessive judicialisation. Notwithstanding, disbelief is developing around cultural expertise; and, excalations of violence and counter-violence signal that European majority and the so-called minorities are drifting apart. Hence our question: Cultural Expertise in Europe: What is it useful for? A comprehensive assessment of cultural expertise was entrenched by its narrow technical definition. This project develops around a new integrated concept of cultural expertise to empirically investigate its use and impact in fourteen European countries. In-context data will be collected through ethnographic fieldwork conducted by a modular team allowing real time analysis and immediate use of results by the stakeholders. The objectives will be to: 1) map the terms, condition, and costs of cultural expertise in private and public law; 2) create a toolkit for measuring the impact of cultural expertise; 3) establish an open access searchable data base for the consultation of cases and solution including cultural expertise; 4) design a teaching and learning module using the cultural expertise impact toolkit; and 5) formulate policy-making guidelines which include tested solutions for a sustainable inclusiveness in Europe.

Keywords: anthropology of law
MILLIKELVIN VISUALISATION OF TOPOLOGICAL ORDER (mVITO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Ireland,United Kingdom
Call: ERC Advanced Grant (ERC-2017-ADG, 2017)
Start date: 2019-01-01
End date: 2024-08-31
Duration (months): 68.0
Total project cost (EUR): 3499176.0
EU funding (EUR): 3431872.25
Participants: 2
Project status: SIGNED

The urgent imperative to discover and understand topological quantum matter (TQM) is based both on the fundamental significance of its rich new physics and on the potential for unprecedented applications e.g. topological quantum computing. Specific topological ordered states, such as topological superconductors, ferromagnetic topological insulators, and topological Kondo insulators, are now the focus of physics research. Their microscopic quantum states have proven very difficult to address experimentally, one reason being the lack of instrumentation designed to deal with their novel measurement challenges, especially in high-resolution visualization of TQM. However, new opportunities for this field, based on discovery of viable new materials and on the development of new visualization techniques, have emerged very recently. Therefore, we propose to develop and utilize a suite of new spectroscopic imaging scanning tunnelling microscope instruments capable of visualizing topological quantum matter at millikelvin temperatures. The objective is to achieve the extremely high energy-resolution required to access the energy gaps and exotic electronic states of TQM. Using these unique instruments, we propose a specific sequence of key experiments on direct visualization and quantitative understanding of topological quantum matter. These include direct measurement of the momentum-space structure of the energy gaps of topological superconductors, ferromagnetic topological insulators, and topological Kondo insulators. We plan atomic scale visualization of the Cooper-pair condensate, the ferromagnetic state, and the heavy-fermion hybridization to explore how the real-space structure of these ordered states influences their topological characteristics. Finally, we propose to visualize scattering interference of topological quasiparticles to detect the spectra of extremely exotic Majorana/Jackiw-Rebbi/Heavy-Dirac states that are predicted for these three topological orders.
NEW MANUFACTURING ROUTES (FOR NiCrSiFeB ALLOYS) TO REPLACE COBALT IN AIRCRAFT COMPONENTS (NEMARCO)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Spain,Spain,Spain,France,France
Call: Replacement of cobalt in Environmental Control System bleed valves (H2020-CS2-CFP11-2020-01, 2020)
Start date: 2021-01-01
End date: 2023-07-31
Duration (months): 31.0
Total project cost (EUR): 749991.25
EU funding (EUR): 749991.25
Participants: 6
Project status: SIGNED

The main objective of NEMARCO is to select the adequate chemical composition(s) and manufacturing process parameters for obtaining sealing rings of nickel self-fluxing alloys that can offer the required performance against high-temperature (HT) wear and overcome the health potential issue regarding wear particles Cobalt alloys (current solution) in cabin air. Two manufacturing routes: Horizontal Centrifugal Casting (CC) and Laser Metal Deposition (LMD), will be studied. The achievement of this objective is based on a well-structured approach that combines (i) a preliminary selection of NiCrSiFeB commercial compositions that can favour manufacturing processability while improving wear behaviour at HT supported by simulation of phase’s formation, segregation, precipitation and diffusion phenomena to predict microstructure formation, as well as process simulation to evaluate specific conditions for solidification. (ii) Robust manufacturing study of both processing routes supported by advanced data analytics of all process and product related variables, allowing to identify those parameters with the highest influence and thus, support in the definition of the optimal manufacturing conditions. (iii) Extensive tribological studies at high temperature. This will support for the selection of the best composition and manufacturing solution of NiCrSiFeB alloys as replacement of the actual Cobalt alloys to produce aeronautic parts. (iv) A rigorous LCA/LCC and a preliminary toxicity analysis, leading to a deeper knowledge of environmental performance and economic impact of the solution. The project will contribute on a reduction of fuel consumption, healthier cabin air and a reduction of costs for a more competitive EU aircraft industry. The implementation is carried out by a multidisciplinary consortium formed by experts in LMD (LORTEK), CC (AZTERLAN), HT behaviour of materials and wear particles characterization (ECL-LTDS and CIDETEC) and LCA/LCC and toxicity analysis (CTME).

Keywords: sealing rings,nickel based self fluxing alloys,nicrsifeb,stellite 6,centrifugal casting,laser metal deposition lmd,hot hardness,reciprocating sliding wear,tribology,toxicity analysis