Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Mathematical Foundations of High-Quality Terrain Models (MFHQTERRAINS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2009-IEF, 2009)
Start date: 2011-07-01
End date: 2013-06-30
Duration (months): 24.0
Total project cost (EUR): 146717.0
EU funding (EUR): 146717.0
Participants: 1
Project status: CLOSED

A digital terrain model is a representation of a real-world terrain in a computer. Terrain models play an important role in geographic information systems, where they are used for numerous purposes, like path planning, visualization, and terrain analysis. One of the main ways to represent a terrain is by a triangulation: some points are sampled from the real terrain, and they are connected by triangles that cover the whole terrain area. This results in a subdivision into triangles. There are many ways to triangulate the points, and choosing the right one is essential to obtain terrain models that represent the real terrain faithfully. In particular, the shape of the triangles is very important: long and skinny triangles should be avoided. However, that is not enough. The current approach to triangulating terrains does not take the elevation of the points into account. This can create artifacts---like spurious pits, interrupted valley lines and artificial dams---, a serious obstacle for performing terrain analysis tasks, especially for hydrology or erosion simulations. This research will study combinatorial and geometric properties of triangulations, in order to design new automated methods to find triangulations with well-shaped triangles and---at the same time---as few artifacts as possible.

Keywords: algorithms,discrete mathematics,computer science
Study of the molecular events induced by specific functional foods with a double targeting to effectively reduce cholesterol levels (CHOLESTENOT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2009-IIF, 2009)
Start date: 2010-09-15
End date: 2012-09-14
Duration (months): 24.0
Total project cost (EUR): 161293.0
EU funding (EUR): 161293.0
Participants: 1
Project status: CLOSED

This proposal is focused on the development of a meat-based functional food (pâté, sausage, snacks etc.) able to effectively reduce cholesterol levels in serum by acting simultaneously at two different levels: (I) reducing endogenous cholesterol synthesis by inhibiting the hydroxymethylglutaryl-CoA reductase (the key enzyme in the cholesterol metabolism) and (II) impairing exogenous cholesterol absorption during digestion by its displacement from the dietary mixed micelles and binding of bile acids during the intestinal digestion to avoid their reabsorption. Edible mushrooms will be submitted to accelerate solvent extraction (ASE) and supercritical fluid extraction (SFE) to obtain (T1) polysaccharides (b-glucans), (T2) statin-like or other metabolites and (T3) ergosterol-derivatives concentrates. These concentrates and their mixtures (T1+T2+T3 in a meat-based food matrix) will be screened for their properties to act as (I) and (II). All samples will be submitted to in vitro digestion and absorption tests (using Caco2 cell models) to study their bioavailability and molecular mechanism of action. Responsible compounds will be identified and quantified by analytical standardized tools (HPLC-, GC-MS etc)

Keywords: nutritional sciences,food technology
Advanced encapsulation technology for sustainable detergency (CAP-IT!)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium,United Kingdom,Italy,Spain,United Kingdom,Germany
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-06-01
End date: 2014-05-31
Duration (months): 48.0
Total project cost (EUR): 1561216.0
EU funding (EUR): 1561216.0
Participants: 7
Project status: CLOSED

The CAP-IT! project aims for developing a deep mechanistic understanding of coating and encapsulation processes to stabilise actives in fluid compacted consumer goods. Seven partners from two companies, three universities, and six European countries will exchange knowledge and personnel to achieve breakthroughs in the field of sustainable detergency. The research programme will involve screening and proof of concept of active-wall materials combinations, process development for particle production, characterisation of particles, and creating an overall holistic model. Innovative aspects of the project include using microfluidic devices, new high throughput screening approaches, new materials to allow the encapsulation of actives for fluid matrices, and novel modelling techniques. The project will combine academic knowledge regarding characterisation, wall materials, theoretical understanding of encapsulation processes, and process modelling with industrial know-how on encapsulation techniques, process up-scaling, and industrial requirements. The project has a balanced mixture of secondments (112 months, 15 people) and new recruitments (108 months, 6 people), and of experience level of the personnel involved. The schedule of secondee visits and a special training and transfer of knowledge scheme were designed to match the work plan and to optimise synergies. Collectively, the consortium has the appropriate combination of analysis and process equipment to perform the work plan. If successful, this project will lead to new insights among the participants in the field of encapsulation for compacted consumer goods. The possibility of further improving prototype capsules and particles after the conclusion of this project offers practical perspectives for long-lasting collaborations, benefiting the knowledge-based economy in Europe.

Keywords: detergency,encapsulation,coating,consumer goods,compaction,membranes,modelling,polymers,films
Using real-time measurements for monitoring and management of power transmission dynamics for the Smart Grid (REAL-SMART)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Switzerland,Norway,Poland,Germany,Austria,Finland
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 1085754.0
EU funding (EUR): 1085754.0
Participants: 10
Project status: CLOSED

Power transmission in Europe is entering a period of significant renewal and technological change because the electrical transmission grids face increases in new and variable energy sources, especially from large scale wind power generators. They therefore face future challenges of operation and control. Changes happening in the process industries will also have an impact on electrical supply because electric motors are taking over from traditional gas turbine drivers for large-scale process equipment such as compressors. On the other hand, new measurement and data acquisition methods such as phasor measurement units are allowing greatly improved observation of the transmission grid. In the light of these changes, there is a need for a new action to give Europe a significant lead in methods for enhanced power transmission system operation using emerging measurement technologies. The REAL-SMART proposal presents a balanced programme of applied R-and-D to address measurement-based monitoring and management of the high voltage transmission grid. It involves electrical transmission system operators, companies that supply technologies and components, and universities. The REAL-SMART consortium is interdisciplinary with experts in electrical power systems, modelling, instrumentation, signal analysis, equipment condition monitoring, and automation of oil &amp; gas processes. The consortium will conduct research and undertake secondments to transfer experience and knowledge both ways between Academia and Industry. The project integrates in-depth understanding of the power system operational issues with analysis of state-of-the-art measurements and first-principles physical knowledge. It will invent and develop state-of-the-art tools that will be deployed by the transmission system operators, and will produce trained and experienced personnel. We aim to take a pivotal role in the creation of technology for intelligent operation of the wide-area transmission grids of the future

Keywords: electrical engineering,power transmission,electricty transmission,phasor measurement unit (pmu),smartgrid,wind power generator,modelling,signal analysis,automation and control
Electrospray-Mediated Delivery of Biological Molecules into Mammalian Cells (TAYLORMED)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ireland,Ireland,United Kingdom
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-08-01
End date: 2015-02-28
Duration (months): 55.0
Total project cost (EUR): 962006.0
EU funding (EUR): 962006.0
Participants: 3
Project status: CLOSED

This partnership has been created to address the critically poor efficacy of existing treatment strategies to treat lung disease, a major health problem in the EU. The project will research and develop a novel process involving electrospray to deliver biomolecule-based drugs into cells. The action requires intersectorial collaboration between partners with complementary expertise in biological drug delivery, mechanical and manufacturing engineering and microfluidics technologies. The problem will be tackled by researching the parameters that influence electrospray generation and its ability to successfully deliver active biomolecules into cells. The term ‘electrospray’ refers to the process where electrical charges are provided to a fluid in order to generate a very fine spray of the fluid. Applications of electrospray technology include mass spectrometry, chemical deposition and colloid thrusters. Recently, the process has been applied to areas of biology such as protein mass spectrometry, depositing biological material during tissue engineering and the production of protein microarrays. However, the fundamental parameters underlying electrospray formation are poorly understood, limiting full exploitation of the potential of this phenomenon. We have developed a novel electrospray system which we have successfully used to demonstrate a novel application of delivering biological molecules into cells such that they remain functional within the cell. This technology holds substantial potential as a novel drug delivery method. In this interdisciplinary action, we aim to increase understanding of the physical processes involved in electrospray generation, to develop the technology and to determine its potential to deliver of a wide range of biological molecules into cells. The project will significantly advance the area of electrospray-mediated drug delivery with major relevance for pharmaceutical/drug delivery/medical device companies, patients and clinicians in the EU.

Keywords: microfluidics,electrospray,aerosols,colloids,taylor cone,drug delivery,gene therapy,therapeutics,lung disease
Unique Nanocarbons from Critically Opalescent Solutions (UNCOS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-07-05
End date: 2014-07-04
Duration (months): 48.0
Total project cost (EUR): 520116.0
EU funding (EUR): 520116.0
Participants: 2
Project status: CLOSED

The principal focus of this project is to synthesise carbon nanomaterials and composites with enhanced mechanical and electrical performance using a novel alternative technology. Carbon nanoparticles and polymer composites are formed from the dissociation of critically opalescent fluids via a UV laser. The aim is to produce such materials in a continuous process where the produced material or composite material is synthesised with its final desirable properties in a single to low number of chemistry steps. The project explores the potential of this novel process for the production of new carbon nanomaterials in close collaboration between an academic partner and an SME with the objectives to produce various carbon nanostructures from critically opalescent fluids, to produce carbon nanomaterials with increased electric conductivity, to produce composite materials with improved mechanical properties, to characterise the properties of the produced carbon nanomaterials, to optimise the process conditions and control the resulting structure of the carbon materials, to develop processes suitable for industrial application, to establish new links between academia and SME, to provide access to academic knowledge and infrastructure to industrial partner and vice versa, and to provide staff in industry and academia with transferable skills. The work programme to achieve these goals includes production of novel carbon nanomaterials from carbon dioxide in batch process (specifically carbon nanotubes, carbon nanofibres, carbon platelets, graphene, carbon layers with controlled dielectric properties, and cross-linked polymer composites), construction of a carbon dioxide reactor system for continuous flow process, production of carbon nanomaterials in continuous flow process, analysis of novel carbon nanomaterials, market analysis, risk assessment, selection and optimization of processes for scale-up, and an intensive knowledge transfer programme.

Keywords: nanotechnology,chemistry,materials science
Quantum Key Distribution Certification (Q-CERT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,Switzerland
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-06-01
End date: 2014-05-31
Duration (months): 48.0
Total project cost (EUR): 771683.0
EU funding (EUR): 771683.0
Participants: 4
Project status: CLOSED

The project Q-CERT intends to gather industrial and academic partners with strong scientific and technical backgrounds in quantum key distribution (QKD) technology, in order to establish research partnerships focused on one common high-level objective: strengthen the security of practical QKD systems by developping techniques and standards (both at the hardware and software level) that will allow cryptographic security evaluation and certification At the hardware level, we will conduct systematic studies of the potential vulnerabilities of QKD systems, by testing experimentally the feasibility of attacks on the optical and electronical layer of the systems. We will in response implement experimentally countermeasures, test their efficiency and develop the theoretical framework allowing to model the entire QKD implementation and prove its security. At the software level, we will push further a formal approach of security proof for an essential part of a practical quantum key distribution protocol : key distillation. We will specify and then develop a software library of key distillation that will present a very high-level of security assurance, validated by the use of formal methods for cryptographic protocol verification. This library will in particular include a state-of-the-art error correction module, based on unidirectional LDPC codes. In order to increase the impact of our work, and to benefit from the fruitful interaction and feedback of the research community, we will publicize parts of our results by integrating them in QKD security standards. The development of such security assurance procedures is expected to greatly strengthen the practical security of quantum key distribution (QKD) systems. We will in particular write security targets for a high-performance QKD system, and for a secure infrastructure relying on a network of QKD links.

Keywords: quantum technology,applied optics,security systems
Identification of Clinically Useful Biomarkers for IGF-I Receptor Signalling n Cancer (BIOMARKERIGF)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ireland,United Kingdom
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 799470.0
EU funding (EUR): 799470.0
Participants: 2
Project status: CLOSED

The Insulin-like Growth Factor I Receptor (IGF-IR) is widely expressed on human tissues and has been shown to promote the growth and invasiveness of cancer cells. It is a potentially important therapeutic target for several major cancers including breast, lung and colon, and has attracted major interest from pharmaceutical companies and clinicians. Currently, at least 70 clinical trials are underway to test several different IGF-IR kinase inhibitors and blocking antibodies. However, unlike some other growth factor receptors the IGF-IR is not amplified or over-expressed in cancer. One of the major challenges to targeting the IGF-IR in cancer is the lack of suitable biomarkers that will a) assess IGF-IR activity in tumours, b) facilitate selection of patients and subsets of tumours that are most likely to respond to inhibitors, and c) monitor responses to IGF-IR inhibition. This programme aims to address this problem by identifying and validating biomarkers for the IGF-IR signalling pathway in cancer. This programme involves a collaboration between researchers at University College Cork who are experts in IGF-I signalling and researchers at Almac Diagnostics who are experts in pharmacogenomic approaches to biomarker discovery in cancer. The research plan will take two complementary approaches: 1) explore the potential of a list of candidate genes that have already been identified in a screen for IGF-IR activity in cancer; and 2) carry out an unbiased genomic screen using a combination of cell models selected as models for IGF-I signalling and proprietary databases that have been collated from different sources, including patient data. The research programme is highly collaborative and includes extensive transfer of knowledge and experience, and exchanges of researchers between the University and Almac. It is anticipated that the results will generate significant interest from scientists, clinicians and the pharmaceutical industry, and have a major impact on an impo

Keywords: igf-i receptor,health sciences,cancer,survival signalling pathways,biomarkers,pharmacogenomics
Strategic partnership for improved basin-scale water quality parameter retrieval from optical signatures (WATERS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Sweden,Finland,Netherlands,Germany,Estonia
Call:  (FP7-PEOPLE-2009-IAPP, 2009)
Start date: 2010-06-01
End date: 2014-05-31
Duration (months): 48.0
Total project cost (EUR): 1954453.0
EU funding (EUR): 1954453.0
Participants: 8
Project status: CLOSED

Europe’s list of achievements in space research and applications have largely delivered through collaboration in ESA and through national efforts. Establishing the GMES programme EU sustains a competitive infrastructure and knowledge to support Earth monitoring. The transfer of these capacities to the public sector and policy makers needs to be realized through active collaboration along the full Research and Technology value chain (research-development-customer/user). As the inland and near-coastal waters are under the strongest anthropogenic impact, there is a need for a better and more efficient way to monitor their ecological status &amp; processes, which is the underlying scientific goal of this proposal. WaterS focuses on creating conditions for strategic dynamic partnerships in the form of long-term cooperation between three excellent research groups with proven high competence and capacity in the field of remote sensing of optically complex waters from Tartu Observatory (Estonia), Stockholm University (Sweden), Finnish Environment Institute (Finland), and three successful and quickly developing enterprises with unique complementary expertise and tools: Water Insight (The Netherlands); Brockmann Consult (Germany); Vattenfall Power Consult (Sweden). The advanced research programme of WaterS consortium will be realized through the following transfer of knowledge programme: • Introduction of the state-of-the-art methods and knowledge in optically complex waters in Nordic waters by researchers of the academia to service developers in the industry; • Supporting the development of new open-service concepts in EO business by exploiting complementary competences and synergy; • Bringing together academic and industry partners in five countries to learn and get familiar with different research and business traditions, cultural aspects and skills requirements.

Keywords: remote sensing,gmes,optical radiometry,gis,optically complex waters,ecological status,inspire