Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
QUANTum mixtures In FLat And Curved geometries (QUANTIFLAC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: SIGNED

Ultracold quantum gases allowed to realize experimentally several paradigmatic models of theoretical physics, such as nonrelativistic bosons and fermions with zero-range interactions. One of the issues driving the last decades of research on quantum gases was understanding how, from these fundamental models, macroscopic structures and quantum phenomena emerge. Along this direction, the most recent advances of the field include the discovery of dilute quantum droplets and supersolidity in gases with long-range interactions. A great deal of experimental and theoretical attention is now directed at identifying novel phases of multi-component Bose or Fermi mixtures with different compositions, different types of interactions, and in various geometries. The QUANTIFLAC project will analyze low-dimensional Bose-Bose and Fermi-Fermi mixtures of ultracold quantum gases, with the goal of engineering minimally-complicated microscopic models displaying exotic many-body effects. We plan to study emergent inhomogeneous structures in bosonic mixtures and self-binding in fermionic mixtures, aiming to determine whether this type of phenomena can be driven exclusively by structureless zero-range interactions. We will also investigate Bose-Bose mixtures confined in various curved geometries, to understand how the interplay of curvature, boundary conditions and topology regulates the macroscopic quantum behavior of the system. This theoretical project has tight connections with various established experimental groups: its results will raise immediate interest and have far-reaching implications for the quantum simulation of matter with ultracold atomic mixtures and for the fundamental understanding of macroscopic quantum aggregates.

Keywords: ultra cold atomic gases,few body physics,two dimensional,one dimensional,quantum gases,curved geometry,superfluid vortices,shell shaped atomic gases
Implementation of Advanced Digital Solutions to increase the circularity of PV panels throughout the full value chain. (SOPHIA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Innovation actions
Countries involved: Spain,Germany,Netherlands,Bulgaria,Türkiye,Lithuania,Belgium,Italy
Call: Increasing the circularity in electronics value chains (HORIZON-CL6-2024-CIRCBIO-02, 2024)
Start date: 2025-06-01
End date: 2028-05-31
Duration (months): 36.0
Total project cost (EUR): 5997302.5
EU funding (EUR): 4896712.75
Participants: 15
Project status: SIGNED

SOPHIA addresses to the problem of photovoltaic panels End of Life, their management and the society awareness on electronic waste management. The project will implement several Advanced Digital Solutions, involving all actors in the value chain, in order to increase the reuse and repair rates of these products. For the evaluation of the State-of-Health and dismantling of PV panels, a robotic prototype based on IA model will be created. In cases where it is not possible to repair and reuse the PV panels , they will recycled by shredding sorting, and specific upcycling processes for each byproduct.", Because of their traceability and information available in the Digital Product Passport (DPP), the panels will be easily identifiable, hence the PV panels will be recycled by type and composition, increasing the quality of the obtained secondary raw materials, thus reducing waste generation. The repaired panels and secondary raw materials will be put up for sale on a marketplace, with the aim that all these products that are marketed have traceability provided by the DPP. Furthermore, in order to achieve goals and high circularity for the panels in the long term, an eco-designed and easy dismantling solar panel will be developed as prototype. It is expected that in the long term, the project will help to increase social and corporate awareness about the panel production impact, aiming towards a full ecodesign practise fully sustainable PV industry. Additionally, SOPHIA will contribute to the generation of new markets around the photovoltaic sector across Europe.

Keywords: pv panel,solar panel,digital product passport,advanced digital solutions,upcycling
Quantum many-body optics in structured low-dimensional systems (QuLowD)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 199440.96
EU funding (EUR): 199440.96
Participants: 1
Project status: SIGNED

Understanding the propagation of light and how it interacts with matter is important in many areas of science and technology. While photons are ideal carriers of information due to their lack of mutual interactions, the ability to induce large optical non-linearities in optical media opens up exciting perspectives for fundamental research and quantum information applications. Interfacing light with individual quantum emitters has made it possible to reach remarkably strong non-linearities on the level of individual photons, which can generate correlated quantum states of light. Structured systems of regularly arranged emitters offer a unique platform with enhanced coherent light-matter coupling and highly suppressed photon losses. However, recent work has so far mostly been limited to the study of linear optics. QuLowD will explore the quantum nonlinear optics of structured emitter arrays in two complementary systems: arrays of ultracold atoms in optical lattices and arrays of long-lived excitons in twisted multi-layer structures of quantum materials. The ambition of QuLowD is to contribute to our theoretical understanding of emergent photon interactions in such novel optical interfaces from the regime of few interacting photons to the many-body physics under strong optical driving. Through close collaborations between two research group led by Thomas Pohl at TU Wien, and associated groups at the Institute for Theoretical Physics (ITP) and the Vienna Center for Quantum Science and Technology (VCQ), QuLowD seek to combine concepts from quantum optics and atomic physics as well as theoretical solid-state physics to advance the understanding of both of these systems. In particular, I will investigate few-body physics of exciton arrays in 2D quantum materials, develop methods to explore the many-body physics of atomic arrays and investigate strongly interacting polaritons in twisted multi-layer structures. Beyond the scope of the fellowship, QuLowD will contribute to the advancement of future quantum information applications based on light-matter interfaces.

Keywords: quantum optics,light matter interaction,open quantum many body systems,ultracold atomic lattices
Carboxylic Esters as Bifunctional Reagents in Decarboxylative Cross-Coupling Reactions and Alkene Functionalizations (DECAF)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-10-01
End date: 2031-09-30
Duration (months): 60.0
Total project cost (EUR): 1499435.0
EU funding (EUR): 1499435.0
Participants: 1
Project status: SIGNED

Transition-metal catalyzed cross-coupling reactions have transformed carbon-carbon bond formation in complex organic molecules, revolutionizing fields like pharmaceutical and agrochemical industries, polymers, and natural product synthesis. Despite their vast applications, these reactions heavily rely on toxic organic halides and organometallic reagents that require multiple preparation steps and often lack stability. Carboxylic esters (RCOOE) offer a promising alternative as they are readily available, potentially bio-sourced, and can serve as bifunctional partners in cross-coupling reactions. The ester’s R and E groups can act as nucleophiles and electrophiles upon carbon dioxide extrusion, forming carbon-carbon bonds (R–E) by recombination in an exergonic transformation. However, unlocking the full potential of esters faces a significant kinetic challenge due to the difficult activation of strong C–O bonds. This challenge has limited applications to reactive substrates like allyl esters (E = allyl). The DECAF project seeks to overcome these barriers by developing groundbreaking multi-catalyst cross-coupling reactions using dialkyl carboxylic esters (RCOOE with R, E = alkyl) as versatile and bifunctional reagents under visible-light irradiation. In the first Strand, DECAF will focus on generating reactive intermediates from the cleavage of ester C–O bonds. Their potential as cross-coupling partners will be demonstrated through the example of Heck-type couplings with alkenes. The second Strand will introduce an electron-borrowing strategy to enable the decarboxylative recombination of esters. This unified mechanistic approach will extend the application of carboxylic esters as bifunctional reagents to catalytic alkene transfer dialkylations and, ultimately, decarboxylative sulfonylations.
Kinetic Pathways to Control Nanocrystal Shapes (kineticSHAPES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-07-01
End date: 2031-06-30
Duration (months): 60.0
Total project cost (EUR): 1492415.0
EU funding (EUR): 1492415.0
Participants: 1
Project status: SIGNED

The shape of nanocrystals is crucial in determining surface area, reactivity, optical properties, mechanical strength, and self-assembly behavior. The current theory on shape formation is based on thermodynamic equilibrium and predicts that each crystal structure should enforce a unique shape, with few morphological variations depending on solution chemistry. Whereas this theory succeeded in explaining crystal habits in mineralogy, it mispredicts many nanocrystals, pointing out the necessity of a non-equilibrium description of shapes. Critical to this project are robust and scalable simulation techniques that capture kinetic effects of ligands and ions in solution at the atomic/molecular scale, while enabling the formation of facets and shapes at mesoscopic scales. Research questions include understanding (i) kinetically trapped shapes in metastable equilibria, (ii) symmetry-breaking from the underlying crystal structure, (iii) the bifurcation of growth pathways leading to synthesis yield, (iv) the emergence of chiral and asymmetric features, and (v) the role of the concentration field in the solution. Central will be the finding of shape diagrams that pinpoint thermodynamic conditions and kinetic factors to tune crystallographic direction and surface area of facets with maximum synthesis yield. Shapes of interest include classic polyhedra, 1D and 2D geometries, multiply twinned particles, concave and high Miller index facets, and branched shapes. This project will allow theory- and computer-aided design and optimization of synthesis protocols of nanocrystals with kinetic shapes.

Keywords: nanocrystal shape,crystal growth,crystallization diffusion,mass transfer limited crystallization,kinetic monte carlo,molecular dynamics,simulation method development,multiscale modeling
Eurasian Network for Collaborative Research on Tree-Root-Mycorrhizal-Pathogen Interactions in Forest Soils (EuAsiaN-ROOT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Czechia,Germany,Italy,Thailand,Kazakhstan,Mongolia
Call: MSCA Staff Exchanges 2023 (HORIZON-MSCA-2023-SE-01, 2023)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 1591600.0
EU funding (EUR): 1591600.0
Participants: 8
Project status: SIGNED

EuAsiaN-ROOT aims to unravel the complex relationships between soil, roots, fungi and pathogens within forest ecosystems. Focusing on forests across the Eurasian climate spectrum, from tropical to highly continental, it will characterise the soil fungal community and mycorrhizal fungi in both roots and soils of these diverse forests. It will also investigate the fine root characteristics of forest trees and key interactions between soils, roots, mycorrhizal fungi and pathogens. It will investigate how mycorrhizal fungi associated with trees in different forest types contribute to ecosystem services such as nutrient acquisition and carbon sequestration and how these contributions are influenced by climate, soil conditions and the unique pressures exerted by soil-borne root pathogens. Through comparative analysis across forest biomes, it aims to identify the respective roles of tree fine roots and mycorrhizal fungi in the provision of ecosystem services. It is essential to identify both abiotic and biotic pressures, particularly soil pathogens, that affect the provision of these services by tree fine roots and other types of mycorrhizal fungi. EuAsiaN-ROOT research will advance scientific understanding and serve as a platform for personal and institutional development and training. EuAsiaN-ROOT's comprehensive training programme, facilitated by secondments, will equip participants with cutting-edge knowledge methodologies, dissemination strategies and insights into policy applications. Recognising the importance of dissemination and communication, we aim to increase soil literacy through practical outreach activities. EuAsiaN-ROOT is interdisciplinary, covering aspects of geology, soil science, forest ecology, forestry and nature conservation. EuAsiaN-ROOT is international, with partners from the Czech Republic, Germany, Italy, Kazakhstan, Mongolia and Thailand. EuAsiaN-ROOT is multisectoral, involving partners from the academic sector and the regional nature park.

Keywords: mycorrhiza,soil pathogens,climate gradient,root traits,asian forests,mineral weathering,soil carbon cycle,soil microbial communities
Vesicular mechanisms of carbon fixation in calcifying cells of marine animals (CarboCell)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental B iology, Ecology  and E volution
Panel description: For all organisms : Ecology, biodiversity, environmental change , evolutionary biology, behavioural ecology, microbial ecology , marine biology, ecophysiology, theoretical developments and mod elling
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-07-01
End date: 2028-06-30
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

The process of biomineralization has profound impacts on the geology of our planet and is an integral part of the global carbon cycle by generating large amounts of CaCO3 bound in coral reefs, chalk mountains and deep sea sediments. Mounting evidence demonstrate that many marine calcifiers generate biominerals by the intracellular formation of CaCO3 from seawater Ca2+ and metabolic CO2. To date, the underlying mechanisms that control the carbonate chemistry in calcifying vesicles are unknown which however will provide ground-breaking insights into a biological process that is capable of transforming a metabolic waste product - CO2 - into a versatile construction material. In the past 5 years my group has developed a unique methodological expertise to study the cellular physiology of calcifying systems. Building on this expertise CarboCell will tackle the important but challenging task to identify and understand the mechanisms of vesicular calcification. The sea urchin larva will serve as a powerful model organism, that represents a prime example for the intracellular formation of CaCO3 and which allows us to employ specifically targeted molecular perturbations in combination with sub-cellular ion and pH recordings. CarboCell will take a stepwise strategy to systematically examine the mechanisms of vesicular calcification on the three main core subjects- carbonate chemistry (WP1), ion/CO2 transport mechanisms (WP2) and vesicular volume regulation and trafficking (WP3). CarboCell will provide a deep mechanistic understanding of the calcification process with strong implications for explaining and predicting responses of marine calcifiers to the global phenomenon of ocean acidification. More importantly, knowledge about the mechanisms that allow organisms to transform CO2 into a construction material will pave the ground for novel, biology-inspired solutions of CO2 capture and utilization – a basic science approach at the core of twenty-first century concerns.

Keywords: biomineralization,sea urchin larva,life cell imaging,physiology,membrane transport,climate change
High-throughput combinatory drugs testing on in vitro 3D cells model platform (SYNEBIO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2023-01-01
End date: 2024-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Drug combinations can lead to the discovery of novel drugs by increasing efficacy or lowering toxicity through synergy. This can boost existing drugs, rescue drug candidates, and accelerate drug discovery for yet poorly addressed diseases. However, predicting synergy is difficult, and finding synergies requires high-throughput screening (HTS) in advanced cell models. Current solutions propose either HTS in 2D cell cultures or low throughput assays in 3D cell cultures, but not both. On the basis of a technology developed in the ERC-funded AbioEvo project, we devised an innovative microfluidic platform for 3D culture and HTS of drug combinations. Miniaturization densifies routine 3D assays, resulting in a throughput increase of 10 to 100 times. Fluidic automation reduces liquid handling 500 times for a 100x100 drug library at a 10-point dose-response combinatorial screening. Furthermore, 3D culture models better predict later physiological responses, thus increasing the success probability of downstream drug development stages. We have shown dose-response measurements of 144 antibiotic combinations on bacteria on a single chip. In this POC, we aim to demonstrate the applicability of our technology to human cells and benchmark it based on existing screens for breast cancer cells. We will adapt the cell culture conditions and data analysis, perform market analysis, and examine industrialization feasibility. This will put us in a position to create a spin-off to reach the preclinical drug screening market and identify the most promising therapeutic areas. Indeed, the technology has the potential to screen for synergistic drug combinations at an earlier stage of the drug discovery process (thanks to miniaturization and automation) while providing a more reliable cellular response for later stages (thanks to 3D culture).
Fast & automated droplet tracking tool for microfluidics (DROPTRACK)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2022-10-01
End date: 2024-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Microfluidics technology targets droplet manipulation by confining fluids to manufacture materials for many industrial applications and life sciences. Data analysis obtained by microfluidic experiments remains a bottleneck to this day due to the lack of a reliable interface converting raw observations to informative data fast enough and at low operating costs. Many computer vision tools exist, which permit to infer useful physical information from video data but they typically target specific physical systems and lack broad applicability. Moreover, the existing tools need intensive development and fine-tuning before they can be useful in a specific scenario. Thus, such a lack of computer vision tools with broad applicability hinders the penetration of this technology for extensive microfluidics applications. This PoC aims to develop a stand-alone, easy-to-use software (DropTrack) that can detect and track individual droplets from experimental videos. Two cutting-edge deep-learning algorithms, YOLO for droplet detection and DeepSORT for droplet tracking, will be at the software's core. DropTrack will provide trajectories of the individual droplets and measure physical quantities of interest, such as the droplet numbers, flow rates, packing fraction, etc., by analyzing videos from experiments. Our preliminary work indicates that DropTrack is capable of analyzing images much faster than the image capture rate of a typical digital camera, thereby opening entirely new prospects for real-time feedback control in experiments. The realization of DropTrack will lead to dramatic time and resources savings in video data analysis of deformable moving objects in microfluidics. Beyond this PoC, the successful demonstration of this technology in microfluidics is expected to attract significant attention as a handy data analysis tool in other relevant fields such as multi-organism biological systems from cell aggregates to animal congregation.