Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
New tools and approaches to control Porcine Reproductive and Respiratory Syndrome (PRRS) in the EU and Asia (PORRSCON)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Collaborative project
Countries involved: Belgium,Spain,Spain,Italy,Switzerland,Denmark,Poland,United Kingdom,United Kingdom,Netherlands,China,Germany,Viet Nam
Call:  (FP7-KBBE-2009-3, 2009)
Start date: 2010-01-01
End date: 2014-06-30
Duration (months): 54.0
Total project cost (EUR): 4092316.53
EU funding (EUR): 2999070.0
Participants: 16
Project status: CLOSED

Porcine reproductive and respiratory syndrome virus (PRRSV) is the major cause of reproductive and respiratory problems in pigs worldwide. Controlling this disease is a top priority in pig producing countries. Due to mutations at a high frequency, new variants of the virus appear that are no longer effectively controlled by the commercial vaccines. In addition, highly virulent variants emerge, leading to high losses. With regard to animal welfare and agricultural economics, there is an urgent need to control PRRS. Furthermore, the abusive use of antibiotics to control PRRSV-associated respiratory problems may lead to resistance that may endanger public health. PoRRSCon is an initiative of 14 partners originating from Europe and Asia with strong expertises in virology and immunology. They are doing frontline research on PRRSV and/or vaccine development. Two of these partners are leading European pharmaceutical companies that will guide the consortium in the direction of exploitable results. By joining their strengths they have an ideal position to be successful in one of the most difficult challenges in pig health, controlling PRRS. To reach this final goal, the following objectives are forwarded:(i) characterize genetically and antigenically current PRRSV isolates in Europe and Asia, (ii) have a better understanding of the complex pathogenesis of PRRSV infections, immune response against PRRSV and immune modulation by PRRSV, (iii) define the genetic base of PRRSV virulence, (iv) identify PRRSV proteins and domains on these viral proteins that are involved in the induction of the immunity against PRRSV and in the immune modulation of PRRSV, (v) develop new generation, efficacious and safe marker vaccines that can be adapted to temporary changes and geographical differences and (vi) develop DIVA assays that allow to differentiate infected from vaccinated animals. At the end, it will be possible to set up a control strategy by combining marker vaccines with DIVA assays

Keywords: prrsv,vaccine,differential elisa,geno/serotyping,pathogenesis,immunity,virulence,t/b epitopes
Improvement of current and development of new vaccines for theileriosis and babesios of small ruminants (PIROVAC)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Collaborative project
Countries involved: Germany,United Kingdom,China,Germany,France,Israel,Switzerland,United Kingdom,Türkiye,United Kingdom,Italy,Portugal,France,Argentina,Netherlands
Call:  (FP7-KBBE-2009-3, 2009)
Start date: 2010-04-01
End date: 2014-09-30
Duration (months): 54.0
Total project cost (EUR): 4059031.4
EU funding (EUR): 2999994.0
Participants: 15
Project status: CLOSED

The proposal deals with the establishment of control measures for two major tick-borne diseases of small ruminants: theileriosis caused by Theileria lestoquardi and T. uilenbergi and babesiosis caused by Babesia ovis. The research programme aims at improving existing and producing new attenuated vaccines, designing subunit vaccines and capability building. To achieve these goals the proposal will assess parasite diversity and identify molecules associated with attenuation of parasite virulence to be included in the development of safe and efficacious live vaccines. For the design of a subunit vaccine parasite molecules will be identified and characterized involved in i) invasion of host cells ii) activation of CD4+ T cells and NK cells for the production of cytokines capable of activating macrophages for killing of the parasites and iii) activation of cytotoxic T-lymphocytes involved in killing of T. lestoquardi-infected leucocytes. For improvement of attenuated vaccines, a combination of vaccine with subunit vaccine will be examined for synergistic effects and reducing the need of a cold chain by improving storage conditions/ shelf life of vaccine will be aimed for. Groups working on Plasmodium are involved with the goal to benefit from the scientific and technological knowledge in this field and to translate it into tools and reagents for small ruminant piroplasms. Industrial expertise regarding vaccine development and delivery systems will be incorporated in the whole project. The impact of the vaccine to be produced against these emerging tick-borne diseases will be enormous, as they pose a great threat to livestock production, and a contribution will be made that will meet critical Millennium development goals: food security, food safety, poverty alleviation, animal welfare and environmental sustainability.

Keywords: malignant theileriosis,ovine babesiosis,theileria lestoquardi,theileria uilenbergi,babesia ovis,attenuated vaccine,subunit vaccine,small ruminant
PLANT food supplements: Levels of Intake, Benefit and Risk Assessment (PLANTLIBRA)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Fork to farm: Food (including seafood), health and well being
Action type: Collaborative project
Countries involved: Italy,Netherlands,South Africa,Finland,Spain,United Kingdom,China,Argentina,United Kingdom,Brazil,Romania,Austria,Netherlands,Belgium,Germany,Switzerland
Call:  (FP7-KBBE-2009-3, 2009)
Start date: 2010-06-01
End date: 2014-05-31
Duration (months): 48.0
Total project cost (EUR): 7818570.67
EU funding (EUR): 5985934.0
Participants: 26
Project status: CLOSED

Plant food supplements, or botanicals, have high acceptance by European consumers. Potentially, they can deliver significant health benefits, safely, and at relatively low costs. New regulations and EFSA guidance are also now in. However, concerns about safety, quality and efficacy of these products remain, and bottle-necks in risk and benefit assessments need to be solved. PlantLIBRA (PLANT food supplements: Levels of Intake, Benefit and Risk Assessment) aims to foster the safe use of food supplements containing plants or herbal extracts, by increasing science-based decision-making by regulators and food chain operators. To make informed decisions, competent authorities and food businesses need more quality-assured and accessible information and better tools (e.g., metadatabanks). PlantLIBRA is structured to develop, validate and disseminate data and methodologies for risk and benefit assessment and implement sustainable international cooperation. International cooperation, on-spot and in-language capacity building are necessary to ensure the quality of the plants imported in the EU. PlantLibra spans 4 continents and 23 partners, comprising leading academics, Small- and Medium-Sized Enterprises, industry and non-profit organizations. Through its partners it exploits the databases and methodologies of two Network of Excellences, EuroFIR and Moniqa. Plantlibra will also fill the gap in intake data by conducting harmonized field surveys in the regions of the EU and apply consumer sciences to botanicals. Existing composition and safety data will be collated into a meta-databank and new analytical data and methods will be generated. The overarching aim is to integrate diverse scientific expertise into a single “science of botanicals”. PlantLIBRA works closely with EFSA since several PlantLIBRA partners or experts are involved in the relevant EFSA Working Groups, and also plans shoulder-to-shoulder cooperation with competent authorities and stakeholders.

Keywords: botanicals,plant food supplements,risk-benefit assessment,safety,science-based decision-making,benefits,health claims,consumer understanding,databanks,adverse events
Molecular Approaches and MetaGenomic Investigations for optimizing Clean-up of PAH contaminated sites (MAGICPAH)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Life sciences, biotechnology and biochemistry for sustainable non-food products and processes
Action type: Collaborative project
Countries involved: Germany,Spain,Italy,United Kingdom,Denmark,France,Germany,Denmark,Canada,Germany,Czechia,Colombia
Call:  (FP7-KBBE-2009-3, 2009)
Start date: 2010-04-01
End date: 2014-03-31
Duration (months): 48.0
Total project cost (EUR): 4515496.0
EU funding (EUR): 2997137.0
Participants: 14
Project status: CLOSED

MAGICPAH aims to explore, understand and exploit the catalytic activities of microbial communities involved in the degradation of persistent PAHs. It will integrate (meta-) genomic studies with in-situ activity assessment based on stable isotope probing particularly in complex matrices of different terrestrial and marine environments. PAH degradation under various conditions of bioavailability will be assessed as to improve rational exploitation of the catalytic properties of bacteria for the treatment and prevention of PAH pollution. We will generate a knowledge base not only on the microbial catabolome for biodegradation of PAHs in various impacted environmental settings based on genome gazing, retrieval and characterization of specific enzymes but also on systems related bioavailability of contaminant mixtures. MAGICPAH takes into account the tremendous undiscovered metagenomic resources by the direct retrieval from genome/metagenome libraries and consequent characterization of enzymes through activity screens. These screens will include a high-end functional small-molecule fluorescence screening platform and will allow us to directly access novel metabolic reactions followed by their rational exploitation for biocatalysis and the re-construction of biodegradation networks. Results from (meta-) genomic approaches will be correlated with microbial in situ activity assessments, specifically dedicated to identifying key players and key reactions involved in anaerobic PAH metabolism. Key processes for PAH metabolism particularly in marine and composting environments and the kinetics of aerobic degradation of PAH under different conditions of bioavailability will be assessed in model systems, the rational manipulation of which will allow us to deduce correlations between system performance and genomic blueprint. The results will be used to improve treatments of PAH-contaminated sites.

Keywords: metagenomics,metablic networks,catabolic diversity,bioavailability
PRessurIzed PEM electrOLYZER (PRIMOLYZER)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Collaborative project
Partnership: FCH (Art-185)
Countries involved: Denmark,Netherlands,Finland,Germany,Spain
Call:  (FCH-JU-2008-1, 2008)
Start date: 2010-01-01
End date: 2012-06-30
Duration (months): 30.0
Total project cost (EUR): 2619754.0
EU funding (EUR): 1154023.0
Participants: 6
Project status: CLOSED

The primary objective of the PrimoLyser project is to develop, construct, and test a cost-minimised highly efficient and durable PEM-electrolyser stack aimed for integrated with domestic µCHPs through a combination of the following activities: 1) Specification done by the end-user(s); 2) Basic material R&D on catalyst & membrane to increase durability & efficiency while reducing cost; 3) Process development to fabricate high performance MEAs; 4) Engineering of a durable, reliable, and robust high pressure PEM stack through CFD modelling and design optimisation; 5) Continuous test for 2,000 hours together with a 1.5 kW µCHP; and 6) An evaluation headed by the end-user(s) The key-targets for the stack are as follows: A) Hydrogen production capacity: 1 Nm3/h; B) Pressure: 10 MPa (100 bar); C) 1.68 V @ 1.2 A/cm2 not only at BoL but also after 2,000 hours of continuous operation; D) Cost: <5,000 € per Nm3 H2 production capacity per hour in series production; and E) Durability: >20,000 hours @ constant load Furthermore, the stack will be liquid cooled to enhance durability and enable easy heat utilisation. This is important as a PEM electrolyser operated with renewable will run when the electricity is cheap and therefore not simultaneous with the µCHP. The PrimoLyser project is scheduled for 2.5 years. The present proposal is phase I in a 2 step development, where phase II will comprise BoP development & full integration of the electrolyser with a µCHP followed by a field test. The Consortium is well balanced, with the following 6 partners complementing one another to achieve the project target goals: i) A PEM FC manufacturing company (IRD Fuel Cells A/S [SME], DK); ii) 3 research centres and universities VTT (FI), Åbo Akademi (FI) & ECN (NL); iii) A leading manufacturer of ion exchange polymers and membranes (Fumatech (DE)); and iv) A subsidiary utility company (Abengoa-Hynergreen [ES])
Jatropha curcas Applied and Technological Research on Plant Traits (JATROPT)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Life sciences, biotechnology and biochemistry for sustainable non-food products and processes
Action type: Collaborative project
Countries involved: Netherlands,Brazil,United Kingdom,France,Guatemala,Madagascar,India,Mexico,Spain,United Kingdom
Call:  (FP7-KBBE-2009-3, 2009)
Start date: 2010-01-01
End date: 2013-12-31
Duration (months): 48.0
Total project cost (EUR): 4156080.2
EU funding (EUR): 2995739.0
Participants: 12
Project status: CLOSED

Jatropha curcas shows a big promise towards sustainable and affordable biofuels. Several groups are working independently towards development of both agrosystems and high quality germplasm of Jatropha, and downstream processing and biodiesel markets. The challenges are to make the big promises come true: high oil yield, low competition with food crops, use in various agrosystems from monoculture plantations, to mixed cropping and use in hedges around agricultural fields. JATROPT aims at linking high quality research groups and companies that are now operating in different continents in order to achieve a large synergy in research and development of jatropha as a biofuel crop. In five Workpackages (Breeding, Genetic tools, Sustainable Agrosystems, Demonstrating and Dissemination), the following aims are pursued: 1) Achieve a world wide germplasm collection of Jatropha curcas, molecularly characterised in order to classify the collection into groups with similar genetic backgrounds; evaluation of elite germplasm of this collection in Asia, Africa and Latin-America; linking segregating population based on parents from different parts of the world and creating a global Jatropha linkage map. 2) Develop genetic information and marker tools (genetics of toxic/low toxic trait, branching patterns; disease resistance) to speed up the breeding process. 3) Develop agrosystems that yield sustainable and affordable biofuels - and interesting uses of the co-products (biomass/protein residues after oil extraction), with a focus on Pro Poor development and on designing systems in which competion for food and fuel can be minimised; 4) Demonstration of the potential of local/regional use of produced biofuels to increase agricultural and general economic productivity will be investigated. 5) Achieve dissemination of knowledge on quality of germplasm, on genetics and sustainable agrosystems setting up distribution of combined packages of agronomic guidelines and germplasm.

Keywords: jatropha,biofuel,breeding,agrosystems,industrial feedstock,sustainability
Next-Generation PEM Electrolyser for Sustainable Hydrogen Production (NEXPEL)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Collaborative project
Partnership: FCH (Art-185)
Countries involved: Norway,United Kingdom,Germany,France,Germany,France
Call:  (FCH-JU-2008-1, 2008)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 3068183.8
EU funding (EUR): 1256286.0
Participants: 7
Project status: CLOSED

The main objective of the NEXPEL project, a successful demonstration of an efficient PEM electrolyser integrated with Renewable Energy Sources, supports the overall vision to establish hydrogen as an energy carrier in a large range of applications in the near future. The very ambitious objectives in the call will be addressed by a top class European consortium which is carefully balanced between leading R&D organisations and major industrial actors from 4 member states. An iterative approach between system, sub systems and components will be applied to define its cost, performance and ecological targets. This will be accompanied by a design to cost exercise as part of the life cycle analysis. Efficiency greater than 75% will be achieved by - developing more effective electrodes - adapting highly conductive new membrane materials - increasing the operating temperature for increased kinetics - lowering the hydrogen cross over using denser membranes - increasing the system pressure to reduce pump losses A stack life time towards 40 000 h will be achieved by - reducing hydrogen cross over reducing chemical degradation by peroxides - developing more stable catalysts, porous current collectors and bipolar plates - designing stack which minimizes temperature and mechanical stress gradients - developing high efficient advanced power electronic minimising load stress for the electrolyser Reducing system costs to EURO 5,000/Nm3 is a major driving force and will be addressed by - replacing/reducing of expensive materials (PFSA membrane, Pt loading, titanium) - increasing the performance of components and sub-systems - simplifying the system - developing components suitable for mass production The consortium is confident that the dissemination and exploitation of the project will create considerable impact especially in terms of Europe’s energy security, reducing greenhouse gas emission and increasing Europe’s competitiveness.

Keywords: pem electrolyser,res integration,sustainable,hydrogen,high pressure
Food And Health Research in Europe (FAHRE)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Fork to farm: Food (including seafood), health and well being
Action type: Coordination and support actions
Countries involved: Portugal,France,United Kingdom,Italy,Germany,Latvia,Sweden
Call:  (FP7-KBBE-2009-3, 2009)
Start date: 2010-01-01
End date: 2012-04-30
Duration (months): 28.0
Total project cost (EUR): 1206369.2
EU funding (EUR): 999218.0
Participants: 7
Project status: CLOSED

FAHRE – Food And Health Research in Europe – aims to increase the structuring of food and health research and support cooperation towards the European Research Area. It will do this by providing a comprehensive map of research funding in the EEA, and identifying the key players and processes involved in research funding and policy at regional, national, and transnational level. Identification of the structures and processes that contribute to determining research funding and policy, and evaluation of their success by analysing the resulting programmes and policies, will direct effort for achieving the ERA goals. The project will also gather information about the current needs of the research environment in this multidisciplinary area, and identify the gaps and overlaps. Strengthening research commissioning in Europe, especially through support of national programmes, will support the Lisbon Agenda of a knowledge-based economy,with better products, better services and better quality of life for European citizens.

Keywords: food,health,era,mapping,research funding and policy structures and processes
Food Refrigeration Innovations for Safety, consumer Benefit, Environmental impact and Energy optimization along cold chain in Europe (FRISBEE)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Fork to farm: Food (including seafood), health and well being
Action type: Collaborative project
Countries involved: France,Belgium,Netherlands,United Kingdom,Belgium,Greece,Norway,Spain,Türkiye,France,France,United Kingdom,Czechia,Hungary,France,Italy,Spain,Netherlands,Netherlands,Belgium
Call:  (FP7-KBBE-2009-3, 2009)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 8165746.2
EU funding (EUR): 5992082.0
Participants: 26
Project status: CLOSED

The objective of the FRISBEE (Food Refrigeration Innovations for Safety, consumers’ Benefit, Environmental impact and Energy optimisation along the cold chain in Europe) project is to provide new tools, concepts and solutions for improving refrigeration technologies along the European food cold chain. At all stages the needs of consumer and European industry will be considered. The project will develop new innovative mathematical modelling tools that combine food quality and safety together with energy, environmental and economic aspects to predict and control food quality and safety in the cold chain. The FRISBEE partners will develop new and emerging refrigeration technologies providing energy efficient and sustainable alternatives to current technologies. The project is constructed around 8 work packages. Management is covered in work package 1. Work package 2 will develop innovative databases of current technologies to enable later comparison between new and current technologies. Work package 3 will develop Quality and Energy/Environment Assessment Tools (QEEAT). In work packages 4 and 5 the team will develop new and emerging refrigeration technologies for representative cold chains selected for applicability to the European food industry. Work from work packages 4 and 5 will be further developed and demonstrated in work packages 6 and 7. Work from the project will be disseminated widely in work package 8. The project involves 26 partners from 12 EU member, associated and candidate countries. Within the consortium, 13 of the partners are companies, 2 are NGOs or represent other companies (mainly SMEs) and the remainder are research based partners. The consortium includes 6 SME partners. The international expertise and synergy of the 26 FRISBEE partners enables the work to be exploited on a European level. Therefore it is expected that the European food industry, related cold chain actors and consumers will all benefit from the FRISBEE project.

Keywords: chilling