Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Improving safety and predictability of complex musculo-skeletal surgery using a patient-specific navigation system (TLEMSAFE)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Towards sustainable and personalised healthcare
Action type: Collaborative project
Countries involved: Netherlands,Netherlands,Germany,Denmark,Belgium,Poland
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-03-01
End date: 2014-08-31
Duration (months): 54.0
Total project cost (EUR): 4315810.0
EU funding (EUR): 3060720.0
Participants: 6
Project status: CLOSED

The burden of Musculo-Skeletal (M-S) diseases and prosthetic revision operations is huge and increasing rapidly with the aging population. For patients that require a major surgical intervention, procedures are unsafe, uncertain in outcome and have a high complication rate. The goal of TLEMsafe is to create an ICT-based patient-specific surgical navigation system that helps the surgeon safely reaching the optimal functional result for the patient and is a user friendly training facility for the surgeons. TLEMsafe is developed by generating automated 3-D image-analyzing tools to parameterize the M-S system. The patient-specific parameters are fed into a recently developed M-S model with which the patient-specific functional outcome can be predicted. This consists of a direct effect (e.g. due to the removal of a muscle in a tumor patient), but has also a secondary effect in the sense that the patient will generate adaptive behavior to the altered M-S system. Implementation of the adaptive capacity will be a unique (but essential) feature which allows valid predictions of the functional effects of surgical interventions. The next step is that the surgeon can virtually operate on the patient-specific model after which the model predicts the functional effects. Once the optimal plan is selected, this is fed into a system that allows the surgeon to reproduce the selected surgical plan during the actual surgery TLEMsafe is a navigation system based on innovative ICT tools for training and pre-operative planning. Extensive, innovative validation techniques including quantitative indicators to improve safety (of surgical operation) and quality (highly predictable effects of complex surgery) are included. The emphasis on the M-S pathologies and the adaptive capabilities of the human M-S system creates a unique system. Co-developing the software of the visual and interactive (surgical) parts with clinicians and companies eases the successful introduction to (future) surgeons.

Keywords: musculo-skeletal surgery navigation model tlem safety functional pre-planning simulation
Mueller cells as regulators of retinal expansion and eye size (MEYEREG)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2009-10-15
End date: 2012-10-14
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

Myopia (or near-sightedness) is a condition where the eye grows larger than normal. It is the fourth most common cause of blindness. There is currently no effective treatment to stop its development, and corrective lenses are used instead to compensate for the excessive eye length. Myopia is a common condition that affects more than one third of the European population, and is anticipated to increase in the future. This project aims to identify the mechanism for malignant eye growth. The retina is a tissue sheet in the eye responsible for photodetection, and Mueller cells are the only cells spanning the entire retinal thickness. During excessive eye growth a signal is transduced from the retina outwards to the hard shell of the eye, the sclera, but the nature of the signal is unknown. We propose that eye size is controlled by alteration of the retinal structure, allowing pressure to act on the underlying tissue as a signal. The contractile tone of Mueller cells can be pharmacologically altered in vitro, by substances implicated in myopia development. We believe that relaxation of Mueller cells either increase the retinal thickness thereby increasing the pressure, or increased retinal elasticity allow the intraocular pressure to act on the pigment epithelium as a signal for eye growth. To reveal the role of retinal and Mueller cell biomechanics in myopia, we will perform rheology measurements on retinae from guinea pig eyes with induced myopia. Comparisons with normal retinae will give a clear understanding if increased retinal elasticity is correlated with myopic development. We will investigate if the retina expands after exposure to drugs causing myopia, and by use of a custom-made device we will study if the retina transduce a mechanical force. To identify new pharmacological targets for intervention we will monitor retinal thickness or elasticity changes after interference with cytoskeletal components, such as microtubules, in Mueller cells.

Keywords: health sciences,ophthalmology,myopia,neurobiology,cell signaling
Cooperative Vehicle Localization for Safe and Susteinable Mobility (COVEL)

Framework: FP7 — Cooperation
Programme: Transport (including Aeronautics)
Destination: Support to the European global satellite navigation system (Galileo) and EGNOS
Action type: Collaborative project
Countries involved: Italy,Germany,France,Italy,Not available,Netherlands
Call:  (FP7-GALILEO-2008-GSA-1, 2008)
Start date: 2010-01-01
End date: 2011-12-31
Duration (months): 24.0
Total project cost (EUR): 3455321.0
EU funding (EUR): 2118525.0
Participants: 6
Project status: CLOSED

The steadily increasing traffic density in Europe is causing enormous negative effects such as accidents or CO2 emissions. Especially in urban areas, traffic jams and other disturbances are daily phenomena. As the capacity of traffic infrastructure can only slowly be further increased, a much more efficient traffic management is necessary to mitigate the negative impacts of road traffic. The aim of the COVEL project is to develop and commercialize the Lane Navigation Assistant (LNA) – an in-vehicle device which will enable lane-level navigation and lane-level traffic management especially in urban areas. The LNA will use satellite positioning as its primary source, whereas these data will be augmented by correction information coming from the EGNOS system. The EGNOS data will be obtained from EDAS and broadcasted to the vehicles using standard Car2Car- / Car2-Infrastructure-communications. Furthermore, the satellite positioning will be enhanced by innovative algorithms for cooperative localization and map matching. The resulting lane-level vehicle positioning will bring navigation and traffic management to a new level of detail and effectiveness. In order to achieve those challenging goals, COVEL will gather partners with outstanding expertise and a wide experience in the field of satellite navigation, communications, and traffic management. The consortium covers the complete value chain and is supported by a traffic management authority and a university. COVEL has a clear intention to commercialize the project outcome and, thus, to provide an innovative end-user product which is based on EGNOS/EDAS. Furthermore, the project will conduct an active dissemination strategy with website and conference contributions and a special focus on live demonstrations. Finally, COVEL will directly contribute to standardization with a special focus on integrating EGNOS data into automotive communications.

Keywords: galileo,edas,cooperative positioning,lane level navigation
Concept for Ionospheric-Scintillation Mitigation for Professional GNSS in Latin America (CIGALA)

Framework: FP7 — Cooperation
Programme: Transport (including Aeronautics)
Destination: Support to the European global satellite navigation system (Galileo) and EGNOS
Action type: Collaborative project
Countries involved: Belgium,Spain,Not available
Call:  (FP7-GALILEO-2008-GSA-1, 2008)
Start date: 2010-02-15
End date: 2012-02-14
Duration (months): 24.0
Total project cost (EUR): 896591.02
EU funding (EUR): 689882.0
Participants: 6
Project status: CLOSED

Ionospheric Scintillation is a major threat to GNSS based applications demanding high levels of accuracy, availability and integrity, including EGNOS-based applications, notably in low latitude areas. The problem is particularly acute in Latin America and will be further amplified with the solar maximum predicted in 2011-2012. The goal of the CIGALA project is to develop ionospheric scintillation mitigation and countermeasures to be implemented and tested in professional multi-frequency multi-constellation GNSS receivers. Therefore, the project will leverage R&D activities coordinated between European and Brazilian experts as well as a wide scale ionospheric measurement and test campaign that will be conducted in Brazil with the support of several local academic and industrial partners.

Keywords: ionospheric scintillation,latin america,measurement,countermeasure,egnos
LASER INDUCED SYNTHESIS OF POLYMERIC NANOCOMPOSITE MATERIALS AND DEVELOPMENT OF MICRO-PATTERNED HYBRID LIGHT EMITTING DIODES (LED) AND TRANSISTORS (LET) (LAMP)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: Italy,Germany,Italy,Lithuania,United Kingdom,Austria
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-06-01
End date: 2013-05-31
Duration (months): 36.0
Total project cost (EUR): 3204770.0
EU funding (EUR): 2300000.0
Participants: 7
Project status: CLOSED

The project described in this proposal aims at developing a new methodology to obtain semiconductor quantum dots (QDs) regioselectively in a polymeric matrix by means of a heating probe (laser). This new method is designed to produce light emitting devices (LED/T) based on semiconductor/polymer nanocomposite emission without using lithographic processes. This type of effect is possible because, after being heated, certain types of molecules produce metal or semiconductor QDs. If this process is carried out in polymeric foil, the resulting nanocomposite can be used for several purposes. It may be particularly appealing for industrial applications since it results in conducting/semiconducting micro/nano-regions in predetermined areas of the polymer without any patterning process. The potential applications of this technology can be utilized in many fields such as memory data storage, labelling of goods and, as proposed in this project, for the construction of displays. Producing a LED/T with this methodology requires selecting several types of polymers, metal-thiolate precursors (both metal and thiol group), lasers and LED/T architectures. To simplify the concept, the whole process sequence involves material synthesis as the first step, then the formation of the polymer/precursor foil, its laser irradiation in specific regions so that only the irradiated region will be enriched with QD, and, finally, testing the LED/T. Combining the electro-optical properties of QDs, the ease of processing of polymers and the use of laser will allow for the construction of a light-emitting device (LED/T) with increased life-time as well as obtaining matrices of LED/Ts (pixels) without any patterning or inkjet processing. The expected results of this project are: i) understanding the mechanism of the nanocomposites formation “in situ” and its optimization and ii) the formation of LED/T with enhanced electro-optical properties (QDs) without the use of any patterning process.

Keywords: laser patterning,led,quantum dots,nanocomposite,polymer
Enhanced Code Galileo Receiver for land management in Brazil (ENCORE)

Framework: FP7 — Cooperation
Programme: Transport (including Aeronautics)
Destination: Support to the European global satellite navigation system (Galileo) and EGNOS
Action type: Collaborative project
Countries involved: Portugal,Spain,Spain,United Kingdom,Brazil,Not available
Call:  (FP7-GALILEO-2008-GSA-1, 2008)
Start date: 2010-02-01
End date: 2012-05-31
Duration (months): 28.0
Total project cost (EUR): 952708.01
EU funding (EUR): 590000.0
Participants: 8
Project status: CLOSED

Taking benefit of the new Galileo ranging signals, the ENCORE project aims to develop a land management application to cover the following needs of the Brazilian market: -Geo-referencing: due to 10267/2001 Federal Law, all the 5 billions properties in Brazil must be linked to the Geocentric Reference System for the Americas (SIRGAS), whose objective is the standardisation of South America geodetic systems. All these properties are subject to surveying. -Urban/rural cadastre: Brazil includes 500 millions of hectares for farming, but one third of them are not properly identified, being occupied informally. This is an important drawback to allow and efficient use of the farmland, an optimised urban planning, and to perform tax collection. The proposed land management application will cover these Brazil’s needs in terms of geo-referencing and cadastre planning, using an Enhanced Galileo Code Receiver as baseline. As an example, it will solve the problem of land regularization at the Legal Amazon area of Brazil. In current GNSS terminals, there is a gap in terms of performances, receiver complexity and price between mass-market and professional devices. Land management applications require precision and accuracy levels from a few to several decimetres that are under-met with current pseudorange-based mass-market receiver and over-met with professional terminals based on phase observables. This situation leads either in a waste of resources (equipment, time, over-qualified staff), or in lack of accuracy. In this project, it is proposed to fill this gap using the new possibilities of the Galileo ranging signals, in particular E5 AltBOC and L1 MBOC. The Enhanced Galileo Code receiver will use them to generate the best possible pseudorange measurements, which are the inputs of the positioning algorithms. This approach reduces the cost of the end-user device, helping the rapid penetration of Galileo technology outside Europe.

Keywords: galileo,land management,brazil,receiver.
Enhanced Road Safety by integrating Egnos-Galileo data with on-board Control system (ERSEC)

Framework: FP7 — Cooperation
Programme: Transport (including Aeronautics)
Destination: Support to the European global satellite navigation system (Galileo) and EGNOS
Action type: Collaborative project
Countries involved: Italy,France,Romania
Call:  (FP7-GALILEO-2008-GSA-1, 2008)
Start date: 2010-01-01
End date: 2011-10-31
Duration (months): 22.0
Total project cost (EUR): 512412.0
EU funding (EUR): 390448.0
Participants: 4
Project status: CLOSED

The general objective of the ERSEC project is concerned with the broadening of the scope of application to road transport of the EGNOS/GNSS (and later Galileo) through an appropriate integration and data fusion with measurement data coming from other measuring instruments. More specifically, the S&T objective of the project is to develop a measuring system - to be used on board of vehicles - able to output the position on the road map of the equipped vehicle and of all the obstacles (such as other vehicles, peoples and any kind of fixed or mobile objects) around it with a measurement accuracy of the order of 0.1 metre at a sampling rate of 100 Hz. The proposed approach is based on an intelligent datafusion of the EGNOS/GNSS sensor positioning measurement, the Road-GIS digital local map data and the measurement data obtained from an instrument set installed on board of the vehicle, including vehicle dynamic sensors and environmental sensors. Beside the hybridization with other sensors, the optimal use of EGNOS (and Galileo in the future) key differentiators (accuracy, integrity) will be a key factor for the success of the project. This challenging target is required to open the possibility to apply the above positioning data to improve the performance of active road safety systems aimed to avoid collision and off road accidents. Furthermore, ERSEC will open new business opportunities for European companies besides collision avoidance applications, resulting an highly accurate and reliable positioning. The scope of the ERSEC project covers the study and development of a prototype of the ERSEC measuring system and two demonstrators. A vehicle will be equipped with the ERSEC prototype measuring system and a set of trials performed. Furthermore, the ERSEC prototype system will be integrated in a vehicle equipped with a Collision Avoidance System and trials will be performed in order to evaluate the positive impacts on road safety of the EGNOS-GNSS data availability.

Keywords: gnss,egnos,galileo,road safety,adas,collision avoidance,data fusion,improved accuracy,integrity,reliability.
Arousal, cortical signal-to-noise, and the ability to sustain attention (ALERT AND FOCUSED)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-05-01
End date: 2013-08-20
Duration (months): 36.0
Total project cost (EUR): 75000.0
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Sustained attention or the ability to maintain an alert, goal-directed focus is critical for many levels of human behavior. Failures of sustained attention occur when there is a transient decrease in endogenous control of behavior leaving one prone to goal-neglect and distraction by irrelevant stimuli. Frequent lapses in sustained attention are a core feature of performance in the elderly, sleep-deprived individuals, and patients with brain injury and mental disorders with attentional components, such as attention-deficit hyperactivity disorder and schizophrenia. Even healthy individuals differ substantially in their ability to sustain attention. Recent studies have linked deficits in sustaining attention to less stable (i.e., more noisy) cortical signals in particular in frontal brain areas. Although recent research has shed light on the neural mechanisms underlying lapses of attention, less is known about how an individual’s ability to sustain attention might be improved. This knowledge is clearly imperative for the development of interventions that can address sustained attention deficits in patients or for individuals who are prone to attentional lapses due to e.g., disturbed sleeping patterns. The aim of this research project is to study the neural and neurochemical mechanisms underlying the ability to maintain an alert, goal-directed focus, and the effects of an alertness training strategy on this ability. We propose to conduct three studies that will test our main hypothesis that increased volitional control of arousal during sustained attention task performance will enhance cortical signal stability, and thereby attentional stability. The third study will examine the effects of the noradrenergic agonist clonidine on the hypothesized interaction between arousal and attention. The proposed research will use a unique multidisciplinary combination of techniques from psychophysiology, neuroscience (EEG and fMRI), psychology, and pharmacology.

Keywords: psychonomics,cognitive science,psychological sciences,experimental psychology
Energy Software Tools for Sustainable Machine Design (ESTOMAD)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: ICT for mobility, environmental sustainability and energy efficiency
Action type: Collaborative project
Countries involved: Belgium,France,Belgium,Italy,Belgium,Italy,Poland
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-02-01
End date: 2012-09-30
Duration (months): 32.0
Total project cost (EUR): 2430498.0
EU funding (EUR): 1599855.0
Participants: 8
Project status: CLOSED

This project addresses all production machine sectors (e.g. machine tools, agricultural machines, textile machines). Design approaches for these machines, which are currently performance and capacity driven, have to evolve to approaches where resource efficiency is optimized. To do so, energy efficiency has to be taken into account as a key parameter in the design process. The main goal of the ESTOMAD project is to develop a methodology and related ICT tools to model, simulate, analyze and optimize energy flows and losses throughout the whole machine. When optimising machine designs, interaction with suppliers is indispensable for getting up-to-date component data. Supporting this interaction is therefore a key aspect of the ESTOMAD goals. To guarantee quick take-up, the methodology will be embedded in an existing, widely used machine design software. Starting from a methodology specification, developments will be made towards multi-domain energy descriptions on different levels. In parallel, a framework will be developed for machine designers to interact with their supplier on energy considerations. Specific tests and measurements will be conducted on a number of benchmarks for verification purposes. Availability of these benchmarks allows for an extended dissemination of project results to the wide machine production sector. After embedding the ESTOMAD methodology on the existing software a number of demonstrators will be realized. The methodology will constitute a useful base for realizing regulations on energy consumption that are under development for many products, including production machinery (EUP directive). Realizing these goals requires a multi-disciplinary team with strong industrial involvement from various applications. The team is composed of two industry-oriented and one basic-research oriented research organization, one SME, three leading manufacturers active in different sectors and a provider of machine design software tools.

Keywords: sustainable machine design,energy efficiency,simulation tools,numerical modelling