Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Evaluating mHealth technology in HIV to improve Empowerment and healthcare utilisation: Research and innovation to Generate Evidence for personalised care (EmERGE)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Spain,Belgium,Croatia,United Kingdom,United Kingdom,Portugal,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Self management of health and disease: citizen engagement and mHealth (H2020-PHC-2014-single-stage, 2014)
Start date: 2015-05-01
End date: 2020-09-30
Duration (months): 65.0
Total project cost (EUR): 5457480.14
EU funding (EUR): 5457480.140000001
Participants: 16
Project status: CLOSED

EmERGE will develop a mHealth platform to enable self-management of HIV in patients with stable disease. The platform will build upon and integrate the existing mHealth solutions operated by pioneering healthcare providers in the UK and Spain and apply a rigorous co-design approach to ensure patient and clinician input to the solution. The platform will provide users with web based and mobile device applications which interface securely with relevant medical data and facilitate remote access to key healthcare providers EATG, the European HIV patient organisation, will provide a direct and deep interaction with representative patients and clinicians from 5 EU countries. The platform and interfaces will be validated in a large study of 3900 patients using a tailored HTA process, MAST, specifically developed for the assessment of mHealth solutions including translatability as a key factor. Based on prior work showing a high uptake rate and use of mHealth in HIV patient populations, EmERGE aims to demonstrate the benefits to patients and simultaneous increases in cost-effectiveness for healthcare providers by reducing face-to-face consultations, estimated at 6000 saved per year within this study alone. Patient reported outcomes will be agreed and used in the assessment and development of the system which also aims to increase adherence and enable frailty to be reported using mHealth technology. Innovation will be given priority from the beginning by developing new business models of care provision, targeting key stakeholders in the EU health provider sector, including policymakers and clinicians, while eliciting demand from patients to highlight and initiate the widespread implementation and compensation of mHealth solutions within the timeframe of the project. Guidelines and policy briefs will be produced to evidence the benefits and disseminate the lessons learned to support the uptake of mHealth for self-management of other chronic diseases.

Keywords: aids,mhealth,health technology assessment,co design,patient empowerment
Talking Hands (Talking Hands)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: SME instrument
Countries involved: Italy
Call: Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-02-01
End date: 2018-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Imagine a device that enables deaf people to talk. Imagine a business that combines profit and social inclusion. Talking Hands is the unique solution with these characteristics. Potential clients effected by deafness (70bl persons worldwide) have not access at devices able to overcome communication barriers. Limix srl developed Talking Hands as two gloves with sensors able to detect hands movements, translate signs in sentences, and play back them through an artificial voice synthesizer. Benefits for potential clients are multiple from an economic, psychological and practical point of view: Talking Hands is low-cost, -high customizable, -it has ecofriendly materials, -it overcomes social exclusion by increasing deaf people communication ability, supporting independence and self-confidence, - It improves deaf employability and access to the labour market. High customization is guaranteed by the high flexibility of Talking Hands supply chain, that will not affect production costs. Customers will be able to take pictures of their hands with a smartphone, create an online 3-D model, order Talking Hands online and receive it at home. With Talking Hands, Limix srl transformed academic results into a real product, and business opportunity. Talking Hands main company objective is to create an innovative, portable, user-friendly and eco-compatible gesture recognition device in order to realize Limix business idea in Europe. The business opportunity stems from the unique characteristics of the solution: - a light, low-cost, innovative, eco-friendly ICT device direct to end-users, - an innovative business model, - a social inclusive device. Beside ICT on Wellbeing sector, Talking Hands innovative H.I.M. Interface has other potential industrial applications by facilitating and safeguarding communications in dangerous environments, also, in the recent fast development of new virtual reality, it will have an important role due to its capacity to increase realistic experiences.

Keywords: deaf communication,sensors,signs language,communication,h m i,industry 4 0,interface,smart factory,social inclusion,wearable,ict glove,eco friendly,innovation,new business model
Dissecting Regulatory Networks That Mediate Dendritic Cell Suppression (CANCER-DC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: Israel
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-01-01
End date: 2023-12-31
Duration (months): 72.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Recent advances have shown that therapeutic manipulations of key cell-cell interactions can have dramatic clinical outcomes. Most notable are several early successes in cancer immunotherapy that target the tumor-T cell interface. However, these successes were only partial. This is likely because the few known interactions are just a few pieces of a much larger puzzle, involving additional signaling molecules and cell types. Dendritic cells (DCs), play critical roles in the induction/suppression of T cells. At early cancer stages, DCs capture tumor antigens and present them to T cells. However, in advanced cancers, the tumor microenvironment (TME) disrupts the crosstalk between DCs and T cells. We will take a multi-step approach to explore how the TME imposes a suppressive effect on DCs and how to reverse this hazardous effect. First, we will use single cell RNA-seq to search for genes in aggressive human and mouse ovarian tumors that are highly expressed in advanced tumors compared to early tumors and that encode molecules that suppress DC activity. Second, we will design a set of CRISPR screens to find genes that are expressed in DCs and regulate the transfer of the suppressive signals. The screens will be performed in the presence of suppressive molecules to mimic the TME and are expected to uncover many key genes in DCs biology. We will develop a new strategy to find synergistic combinations of genes to target (named Perturb-comb), thereby reversing the effect of local tumor immunosuppressive signals. Lastly, we will examine the effect of modified DCs on T cell activation and proliferation in-vivo, and on tumor growth. We expect to find: (1) Signaling molecules in the TME that affect the immune system. (2) New cytokines and cell surface receptors that are expressed in DCs and signal to T cells. (3) New key regulators in DC biology and their mechanisms. (4) Combinations of genes to target in DCs that reverse the TME’s hazardous effects.

Keywords: dendritic cells,ovarian cancer,single cell rna seq,crispr screen,genetic interactions
STRATEGIC PLANNING OF REGIONS AND TERRITORIES IN EUROPE FOR LOW-CARBON ENERGY AND INDUSTRY THROUGH CCUS (STRATEGY CCUS)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Coordination and support actions
Countries involved: Germany,Spain,Croatia,Romania,Norway,Greece,Poland,France,France,United Kingdom,Portugal,Portugal
Call: Strategic planning for CCUS development (H2020-LC-SC3-2018-NZE-CC, 2018)
Start date: 2019-05-01
End date: 2022-07-31
Duration (months): 39.0
Total project cost (EUR): 3069473.75
EU funding (EUR): 2959533.75
Participants: 18
Project status: CLOSED

The STRATEGY CCUS project aims to elaborate strategic plans for CCUS development in Southern and Eastern Europe at short term (up to 3 years), medium term (3-10 years) and long term (more than 10 years). Specific objectives are to develop: •Local CCUS development plans, with local business models, within promising start‐up regions; •Connection plans with transport corridors between local CCUS clusters, and with the North Sea infrastructure, in order to improve performance and reduce costs, thus contributing to build a Europe-wide CCUS infrastructure. As recommended by the SET Plan Action 9, the STRATEGY CCUS project will study options for CCUS clusters in Eastern and Southern Europe, as at present the CCUS clusters being progressed are concentrated in Western Europe around the North Sea. Therefore, the project is timely for the strategic planning for CCUS development in the whole of Europe. Strategic planning will consider 8 promising regions, within 7 countries (ES, FR, GR, HR, PO, PT, RO) representing 45% of the European CO2 emissions from the industry and energy sectors. These regions satisfy CCUS relevant criteria: presence of an industrial cluster, possibilities for CO2 storage and/or utilization, potential for coupling with hydrogen production and use, existing studies, and political will. The methodology starts with a detailed mapping of CCUS technical potential of the regions together with a comprehensive mapping of local stakeholders and a process for their engagement. This will pave the ground for CCUS deployment scenarios including assessment of 'bankable' storage capacity, economic and environmental evaluation. The project strength relies on of a highly skilled consortium with experience on the whole CCUS chain as well as key transverse skills. CCUS development plans will be elaborated in close cooperation with stakeholders, through the Regional Stakeholder Committees and the Industry Club, to ensure plans can be implemented, i.e. socially acceptable.

Keywords: ccus,ccus development scenarios,ccus clusters,co2 utilisation,co2 geological storage,european ccus infrastructure,ccus in southern and eastern europe,business model,climate change mitigation
scalaBle and grEen wireleSs coMmunications for a sustAinable netwoRked socieTy (BESMART)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

The goal of the project is to develop energy-efficient and scalable designs for distributed mobile networks operated by renewable energy sources, and with very limited signaling overhead and computational complexity. The project will design wireless networks, composed by smart nodes, which are able to perform the following tasks: 1) Self-configure, autonomously allocating their own physical layer radio resources through energy-efficient, feedback-aware, and complexity-aware radio resource allocation. 2) Self-sustain by harvesting energy from renewable and intermittent energy sources, such as solar and wind, as well as from dedicated radio frequency signals present over the air. 3) Sharing or trading energy with other network nodes in order to prolong the lifetime of nodes which are low on battery and to obtain a more fair energy distribution across the whole network. The long-term vision of the project is to kick-start a paradigm shift from core-centric, throughput-optimized networks, towards device-centric, energy-optimized networks. The development of autonomous, energy-independent, and self-organizing wireless networks will enable: a) 100% coverage in urban environments in a power efficient manner; b) network coverage in remote/developing areas where currently it is commercially unattractive to do so. These advancements will make the vision of a connected society sustainable, almost zeroing the operational expenses related to power and hence revolutionizing the business models for ICT by radically reducing energy costs. This will also facilitate the rise of new markets and applications in remote areas, which contributes to closing the digital divide between densely populated and scarcely populated or rural areas.

Keywords: energy efficiency,5g networks,stochastic networks,green network design
Industrial Innovation in Transition (IIT)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Research and Innovation actions
Countries involved: Austria,Spain,Finland,Netherlands,United Kingdom
Call: The European growth agenda (H2020-EURO-SOCIETY-2014, 2014)
Start date: 2015-02-01
End date: 2017-07-31
Duration (months): 30.0
Total project cost (EUR): 2377619.0
EU funding (EUR): 2377619.0
Participants: 5
Project status: CLOSED

Industrial innovation has changed fundamentally over the last ten years. Companies have widely adopted new tools such as open innovation, innovation networks and ecosystems, systemic innovations, public/private partnerships, crowd sourcing, social media, and demand based innovations. These new practices have improved the innovation capabilities of companies and brought new challenges to the traditional innovation policy instruments. This project will examine widely companies’ current use of new innovation practices around Europe and the best practice experience of their use. It will also evaluate existing innovation policy portfolios at national and European levels, and analyze the differences between innovation processes and management practices in different industrial sectors. The best practices and other results will be disseminated widely both to the European business community and governments to improve Europe’s innovation potential. International organizations such as the OECD and the ERT, industrial associations and government agencies are actively participating in the study and in the wide dissemination of its results throughout Europe. The study will cover key industrial sectors in 11 EU Member States, with a survey aiming to achieve a response from some 800 companies. Coverage includes countries classified by the EU as Innovation Leaders, Followers and Moderate Innovators. The project will produce a toolbox for use comparative studies in other countries and use the data base created by the study to benchmark their innovation capacity against the best European practice. Some countries have already indicated their interest to conduct comparative national studies. International research has widely shown the crucial contribution of high innovation performance to economic growth and job creation. This project will improve European industry’s innovation capacity and its competitiveness and thereby help to restore economic and social development in Europe.

Keywords: industrial innovation
Next Generation of Cutting Tools Using Additive Manufacturing Technology I, Phase 1 (3DTTool)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Denmark
Call: Accelerating the uptake of nanotechnologies advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-06-01
End date: 2016-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Our goal is to develop the next generation of thread cutting tools by using additive manufacturing technology (3D printing). Thread cutting tools are used to make screw threads – the main building blocks of modern day machinery. However, these tools have developed very little since they were invented over 100 years ago besides alternating materials used or adding new coatings for the tools to make them stronger. The total Tool Cutting industry worldwide is estimated to be about €17.2 b with average annual growth of about 4% . The bulk of the industry operations are within specific segments: offshore, maritime, automotive and mining – and most of these clients require highly customised tools due to the nature of their business. As such, the Tool Cutting industry spans broadly and innovations that spur new products and ways of working will have far-reaching and important consequences. Printing thread cutting tools in 3D will bring about a high level of innovation to this mature and stagnating industry and will bring about clear and much needed benefits compared to the existing solutions: 1. Improved performance: reduced wear-rate to increase cut rates by 30%-50% 2. Disruptive solution to cooling and lubrication issues: current tools are severely lacking in this aspect 3. Short production lead-time: the new tools reduce production time from 4-14 weeks to 1 week 4. Lightweight product for easy handling: 3D printing enables 60% lighter tools 5. Price competitive offering: expected savings of 10%-30% compared to conventional tools 6. Environmentally friendly product: no waste by-product 7. High-level of client driven customisation: designing in 3D offers full flexibility and adaptation Thürmer 3D Tools project is situated at TRL6 as a technology demonstrated in an industrially relevant environment. We therefore propose a Feasibility Study to verify the technical, commercial and financial viability of the 3DTTool concept with a view to continue to a Phase 2 application.

Keywords: thread cutting tools,3d printing,additive manufacturing,maritime,offshore,machine taps,custom,tools,custom design
Embedded Network Services for 5G Experiences (5G ESSENCE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Partnership: 5G PPP (cPPP)
Countries involved: Spain,Spain,Germany,Germany,Spain,Spain,Ireland,Italy,Italy,Germany,Italy,Cyprus,Greece,Greece,Greece,Poland,France,United Kingdom,United Kingdom,United Kingdom
Call: 5G PPP Research and Validation of critical technologies and systems (H2020-ICT-2016-2, 2016)
Start date: 2017-06-01
End date: 2019-11-30
Duration (months): 30.0
Total project cost (EUR): 7982397.5
EU funding (EUR): 7978272.5
Participants: 24
Project status: CLOSED

5G ESSENCE addresses the paradigms of Edge Cloud computing and Small Cell as a Service by fuelling the drivers and removing the barriers in the Small Cell market, forecasted to grow at an impressive pace up to 2020 and beyond and to play a key-role in the 5G ecosystem. 5G ESSENCE provides a highly flexible and scalable platform,able to support new business models and revenue streams by creating a neutral host market and reducing operational costs by providing new opportunities for ownership, deployment,toperation and amortisation. The technical approach exploits the benefits of the centralisation of Small Cell functions as scale grows through an edge cloud environment based on a two-tier architecture: a first distributed tier for providing low latency services and a second centralised tier for providing high processing power for computing-intensive network applications. This allows decoupling the control and user planes of the Radio Access Network (RAN) and achieving the benefits of Cloud-RAN without the enormous fronthaul latency restrictions. The use of end-to-end network slicing mechanisms will allow sharing the 5G ESSENCE infrastructure among multiple operators/vertical industries and customising its capabilities on a per-tenant basis. The versatility of the architecture is enhanced by high-performance virtualisation techniques for data isolation, latency reduction and resource efficiency, and by orchestrating lightweight virtual resources enabling efficient Virtualised Network Function placement and live migration. 5G ESSENCE leverages knowledge, SW modules and prototypes from various 5G-PPP Phase-1 projects,SESAME being particularly relevant. Building on these foundations, very ambitious objectives are targeted, culminating with the prototyping and demonstration of 5G ESSENCE system in three real-life use cases associated to vertical industries, i.e., edge network acceleration in a crowded event, mission critical applications, and in-flight communications.

Keywords: small cells,mobile edge computing,cognitive network management,radio access network ran controllers,lightweight virtual resources,network slicing,multi tenancy,prototyping and demonstration
Dall Energy Biomass System (DEBS)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Denmark
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-08-01
End date: 2016-10-31
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Problem By 2050 the EU aims at reducing its greenhouse gas emissions by 80-95% when compared to 1990 levels, requiring a transition from fossil fuels to renewable energy such as biomass. Both the emissions from and the price of converting biomass to energy must be reduced if biomass is to compete with fossil fuels. Solution – the innovation Dall Energy has developed a new, disruptive biomass furnace, which integrates several independent innovations into a novel concept for conversion of biomass into energy with at least 10% lower investment and 40-60% lower operational expenses, while at the same time reducing emissions to unprecedented low levels. Customers and market Dall Energy targets three market segments, district heating, energy for industry and power production (in go-to-market order) of which the first alone constitutes a market value in EU of €17-19 billion, showing a growing trend. Impacts Customers are offered lower investment and operational costs, minimal emissions, easier operation and high modulation capability. The reduced costs of energy from biomass will reduce or even bring down a critical barrier for EU to bring greenhouse gas emissions down, potentially having a tremendous impact on society. Dall Energy expects a turnover of €83m and 1,810 jobs created by 2020 and EU will see a solution that is able to bring down emissions and increase both economic and technical efficiency as set forward by directive 20165/2193. The project Commercial hypotheses will be tested through premium price models targeted turnkey partners, analyses of the market situation and risk assessments. Technical features of the Dall Energy furnace will be presented to four named potential turnkey partners, and they will give feedback on sales and price models, implementation strategy in production setup, and product application, product features and potential for further application development.

Keywords: biomass furnace