Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Optimising the policy mix by the development of a common methodology for the assessment of (socio-) economic impacts of RTDI public funding (CIA4OPM)

Framework: FP7 — Capacities
Programme: Support for the coherent development of research policies
Destination: Coordination of research policies
Action type: Coordination and support actions
Countries involved: Belgium,Austria,Iceland,Türkiye,Malta,Spain,Sweden,Czechia,Bulgaria,France,Estonia
Call:  (FP7-COH-2007-2.2-OMC-NET, 2007)
Start date: 2009-03-27
End date: 2011-03-26
Duration (months): 24.0
Total project cost (EUR): 1114806.8
EU funding (EUR): 990458.0
Participants: 15
Project status: CLOSED

The project will establish a network of policy actors with the goal of exchanging information and learning from each other on national activities with respect to the assessment of (socio-) economic impacts of public funding (policies and instruments) of Research, Technological Development and Innovation (RTDI) in the areas of (i) enhancement of private R&amp;D investment; (ii) improved cooperation between public research institutes and private enterprises; and (iii) improved management of research institutions and universities. The project will develop better harmonised (amongst Member States/ regions) methodologies (toolbox/manual) for the alignment/coordination of impact assessment of public RTDI funding, and will assess the usefulness of impact assessment tools in the development of an appropriate policy mix.

Keywords: impact assessment - harmonisation - policy mix - private r&d - industry science relations - monitoring universities
Targeted R&D Policy (TARGET)

Framework: FP7 — Capacities
Programme: Support for the coherent development of research policies
Destination: Coordination of research policies
Action type: Coordination and support actions
Countries involved: Slovenia,France,Lithuania,United Kingdom,Israel,Spain
Call:  (FP7-COH-2007-2.2-OMC-NET, 2007)
Start date: 2009-07-01
End date: 2011-09-30
Duration (months): 27.0
Total project cost (EUR): 949130.79
EU funding (EUR): 839950.0
Participants: 8
Project status: CLOSED

Radical changes in the global economy expose business sectors to major threats as well as to various new opportunities. Policy makers are required to target subsequent opportunities by enabling or promoting the business sector to take advantage of them. However, existing horizontal R&amp;D policies focused on promoting R&amp;D activity in individual firms are often lacking in this respect. Current and future scenarios require not only the design of new policies but also the adoption of a whole new type of policy process, namely the formulation of &apos;Targeted R&amp;D&apos; policies. Such policies go beyond market failure approach to identify strategic priorities as well as analysing system failures and imperfections impeding their successful implementation.. The aim of the TARGET project is to design and develop a structured and valorized set of guidelines &amp; recommendations, cumulating into a toolkit, for formulating and implementing targeted R&amp;D policies, with a focus on the life science/biomed sector. The toolkit will address issues such as: the ability to define strategic priorities, to evaluate technological gaps, to identify the elements within the national/regional innovation system responsible of achieving the selected priorities (including the missing elements), to identify potential system failures, to formulate effective policies and to reach coordination among the relevant policy makers/ministries. A consortium consisting of 8 partners from 6 different countries is assembled to implement the project. The consortium brings together public bodies, and research institutes, whose research will provide a sound base for decision-making in science and policy. The TARGET project will stimulate a mutual learning process among the consortium partners for the identification of the proper mix between horizontal R&amp;D policies and targeted ones.

Keywords: targeted r&d,generic r&d,innovation,research policy,innovation policy,toolkit,benchmark study,system failures,strategy,strategic priorities,coordination,learning process
Inter-sectoral mobility of researchers in South-Eastern Europe (I-SEEMOB)

Framework: FP7 — Capacities
Programme: Support for the coherent development of research policies
Destination: Coordination of research policies
Action type: Coordination and support actions
Countries involved: Greece,Türkiye,Bulgaria,Serbia,Croatia,North Macedonia,Bosnia and Herzegovina,Romania
Call:  (FP7-COH-2007-2.2-OMC-NET, 2007)
Start date: 2009-01-01
End date: 2012-06-30
Duration (months): 42.0
Total project cost (EUR): 767744.3
EU funding (EUR): 658160.25
Participants: 9
Project status: CLOSED

The I-SEEMob project is a bottom-up policy coordination initiative undertaken by 8 countries in the region of South-eastern Europe (SEE). The proposal focuses on the specific research policy issue of enhancing the career development and the intersectoral mobility of R&D personnel in SEE. The aim of the project is to develop a set of policy recommendations targeting national governments for the removal of existing legal and policy obstacles hampering the intersectoral mobility of researchers and their career development towards the realization of the Lisbon Strategy goals. The main activities that are foreseen to be carried out are: a mapping exercise on the current state of industrial representation on R&amp;amp;D sector in SEE and its respective needs; a legislation gap analysis; an exploration of synergies with other networks or initiatives in SEE and EU and, finally, the development of a set of policy guidelines for national governments so as to formulate research policies based on the EC reforming processes of Lisbon Strategy and its relevant policy tools. The impact of the project is expected to be the formulation of national research policies that will take under consideration the results of the I-SEEMob project towards the removal of existing intersectoral mobility obstacles in SEE countries, the enhancement of cooperation between industry-academia, and, accordingly, the realization of the ERA goals in the region.

Keywords: career development of researchers,intersectoral mobility,brain drain,policy recommendations,policy formulation,era
Why do plants make (p)ppGpp? (GREENMAGIC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-09-01
End date: 2011-08-31
Duration (months): 24.0
Total project cost (EUR): 173968.74
EU funding (EUR): 173968.74
Participants: 1
Project status: CLOSED

Under stress bacteria accumulate the potent chemical messenger (p)ppGpp, which drives global changes in transcription that allow the bacteria to adapt and persist. Remarkably the ability to synthesise (p)ppGpp is conserved in plant chloroplasts, organelles that are descended from an ancient prokaryotic endosymbiont. However, very little is known about the role (p)ppGpp plays in plants. We propose to (a) artificially manipulate (p)ppGpp levels and analyse the downstream responses of the plant, and (b) examine how (p)ppGpp synthesis is controlled and how these control mechanisms are wired into known stress and developmental signalling pathways. Discovery of the role of (p)ppGpp in plants will allow us to better understand how plants adapt to stress, how chloroplast development and photosynthesis are regulated, and how an ancient endosymbiont became integrated into a eukaryotic cell. This knowledge will be important for improving crops to face the challenges of a changing climate and uncertain energy supplies.

Keywords: molecular biology,plant growth,arabidopsis,signalling,stress
Identities in Transition: Understanding ethnicity and its intersection with gender, religious affiliation and socio-economic position in comparative perspective (TRANSID)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2010-01-20
End date: 2011-01-19
Duration (months): 12.0
Total project cost (EUR): 102518.3
EU funding (EUR): 102518.3
Participants: 1
Project status: CLOSED

This project investigates ethnic identity and its intersection with gender, religious affiliation and socio-economic position in comparative perspective. It will explore how the identity of members of minority ethnic groups is shaped and re-formed over generations, including being reformulated as religious identity. It will examine how identification is mediated by gender. The research will take a comparative approach investigating the role of national context in ethnic and religious identification. The programme of research will comprise the following interlocking and complementary components: 1. an investigation of the ways in which those of migrant background identify in terms of national identity and values, and the intersection between religious and ethnic identification: exploring variation in relation to socio-economic position; 2. a study of children of interethnic unions: their ethnicity and their socio-economic position relative to children from ethnically homogamous unions; 3. consideration of the ways in which ethnic and religious identification vary by gender, of the relevance of gender and gender roles in mediating ethnic and religious identification and of the ways in which this varies with background and socioeconomic context. This quantitative sociological project will be carried out using secondary analysis of survey data for a number of European countries and employing advanced statistical techniques. Its rationale and approach will be founded in sociological theories of identity, ethnicity and social stratification, but will draw on insights from economics and psychology.

Keywords: social sciences,sociology,social changes,socio-economic research,identity,religion,ethnicity,cross-national,comparative
The SRA domain: a connection between DNA methylation and histone modifications within the epigenetic code? The Arabidopsis VIM family. (SRA AND EPIGENETICS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-IOF-2008, 2008)
Start date: 2009-12-01
End date: 2012-11-30
Duration (months): 36.0
Total project cost (EUR): 237283.61
EU funding (EUR): 237283.61
Participants: 1
Project status: CLOSED

Heterochromatin in both mammals and plants is associated with methylation of cytosines within the DNA sequence. While DNA methylation is widespread in plants, fungi, and animals, it has been curiously lost in Saccharomyces cerevisiae, Schizosaccharomyces pombe, Caenorhabditis elegans, and Drosophila. However, the methylation system in Arabidopsis is very similar to that in mammals, showing that DNA methylation is highly conserved, and that Arabidopsis is an excellent model system to study it. DNA methylation is controlled by two different but equally important processes: establishment and maintenance. Two classes of DNA methyltransferases, DNMT3 and DNMT1, respectively, are responsible for them, and are conserved between mammals and plants. Maintenance DNA methyltransferases methylate hemi-methylated sites upon DNA replication, so that the methylated or unmethylated status is inherited on both of the two newly synthesized DNA molecules. Therefore, DNA methylation serves as a marker on genomic DNA that can persist over cell generations. Evidence suggests that methylation DNA is linked to the methylation status of the surrounding histones, a self-reinforcing feedback loop for the maintenance of DNA and histone methylation that may help to explain the remarkable stability of epigenetic silent states. A group of proteins with a methylated DNA-binding domain, the SRA domain, from both Arabidopsis and humans has been recently discovered with a potential role in recognizing hemymethylated DNA and interacting with chromatin remodeling factors. In this proposal, I plan to characterize the role of the Arabidopsis SRA-domain containing proteins family (VIM family) in DNA methylation control, and how this is related with histone acetylation and methylation in a way to regulate gene transcription and the epigenetic code.

Keywords: plant genetics,arabidopsis,epigenetics,dna methylation,histone modification,orth,vim,sra,functional biology
Mechanically Interlocked Actuating Conjugated Polymers (MIA-CP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-IOF-2008, 2008)
Start date: 2009-08-01
End date: 2012-07-31
Duration (months): 36.0
Total project cost (EUR): 237595.46
EU funding (EUR): 237595.46
Participants: 1
Project status: CLOSED

This proposal details the preparation of novel electromechanical polymers based on mechanically interlocked molecules. These synthetic muscle-like fibres would function via entirely new mechanisms of actuation and have potential applications in the medical, engineering and nanotechnology sectors. In general terms the overall project aim is to couple the latest catalytic mechanical bond-forming methodologies with recent advances in conjugated polymer synthesis to formulate a new generation high performance electromechanical materials. This multidisciplinary research programme integrates aspects of organic, supramolecular and physical chemistry together with materials science. The project objectives will be achieved via a three phase research programme that combines realistic project milestones with focused training activities in materials processing and analysis. The research would be carried out by a promising European scientist at MIT, USA under the supervision of Prof. Swager and at the University of Edinburgh, UK in the group of Prof. Leigh. The researcher’s previous experience in organic/supramolecular chemistry and successful academic track record would be exploited during the initial phase of the project and then complemented by intensive training in polymer preparation, processing, analysis and electromechanical device testing. The advanced training provided by the outgoing host would then be applied during the reintegration period through mentoring and collaborative activities. Overall this research programme would facilitate scientific advances at the interface between molecular devices and materials science, foster collaboration between world leading groups in the US and Europe and would effectively bridge the gap between the researchers current position as a skilled research scientist and a position of complete academic independence and professional maturity.

Keywords: carbon chemistry,instrumental techniques,polymer chemistry,homogenous catalysis,nanotechnology,molecular devices,rotaxanes,conjugated polymers,actuating materials
Circadian regulation in the control of insulin and glucagon release and its role in Type 2 diabetes (CIRCADIAN REGULATION)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-05-15
End date: 2011-05-14
Duration (months): 24.0
Total project cost (EUR): 155236.08
EU funding (EUR): 155236.08
Participants: 1
Project status: CLOSED

Diabetes Mellitus is considered a bihormonal disorder that involves insulin resistance and insulin deficiency as well as relative or absolute high levels of glucagon. Recently, a strong association has been found between disturbances in circadian rhythms and metabolic disorders such as Diabetes Mellitus and Obesity. In this proposal we will use in vitro techniques to knockdown several clock genes in mouse pancreatic islets, MIN6 and alpha-TC1-9 cell lines to establish the role of clock genes in insulin and glucagon secretion. We will examine the circadian regulation in type 2 diabetes in db/db mice to determine whether disturbances in insulin and glucagon secretion are due to disregulation of circadian rhythm in the pancreas. We will also examine the effect of nutrients in the expression pattern of clock genes by performing in vivo studies in mice. Thus, the overall aim of this proposal is to determine whether clock genes can regulate the secretion of insulin and glucagon and whether pancreatic circadian clock can be involved in the irregular secretion of these hormones in Diabetes.

Keywords: clock genes,circadian rhythm,glucagon secretion,insulin secretion,diabetes
Unraveling key abiotic and biotic interactions for sustainable anaerobic biotransformation of chlorinated solvents in groundwater (ANDEMIC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-IOF-2008, 2008)
Start date: 2010-03-01
End date: 2013-04-30
Duration (months): 36.0
Total project cost (EUR): 226833.84
EU funding (EUR): 226833.84
Participants: 1
Project status: CLOSED

Chlorinated solvents are potential carcinogens frequently found in groundwater and are classified as priority pollutants. Anaerobic biotransformation of these compounds to non-toxic ethene via reductive dechlorationation is carried out by microorganisms living in consortia. Bioaugmentation – the addition of active microbial cultures to a contaminated site – is a low-cost and potentially highly effective remediation alternative, particularly for chlorinated solvents, where dechlorination is carried out by very specialized microbes not present at every site. However, there remain serious scientific gaps to more widespread adoption of bioremediation and bioaugmentation. Diagnostics and prognostic monitoring approaches are critically needed to improve our ability to sustain high rates of microbial activity and make bioremediation more reliable and more predictable. This project aims at providing new insights into the biogeochemical interactions affecting chlorinated solvent bioremediation in subsurface anaerobic environments. A stable microbial consortium (KB-1) developed in the Edwards’ lab (Univ. of Toronto) and used commercially for bioaugmentation at field sites will be used as a model for lab-based and field experiments. The project will address three major issues: a) unravel contaminant metabolism and important interspecies interactions in mixed microbial communities with the help of metagenome sequences and metabolomic profiling, b) identify biomarkers through molecular screens and isotopic fractionation signatures to monitor biodegradative mechanisms and the key players involved in these processes and c) understand critical abiotic-biotic interactions and physiological influences on microbial activity in the subsurface at contaminated sites. Knowledge gained from this project will help establishing a sound basis for future research to find new consortia capable of biodegrading other priority pollutants and new chemicals entering our soils and waters.

Keywords: anaerobic biodegradation,bioaugmentation,chlorinated solvents,groundwater pollution,environmental technology/monitoring,metagenome,metabolome,molecular biomarker,natural organic matter,stable isotopes
Tracing the History of Isotope Sciences in Europe: Circulation and Uses of Radiocarbon, 1945-1965 (EUROISOTOPES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IEF-2008, 2008)
Start date: 2009-09-14
End date: 2011-09-13
Duration (months): 24.0
Total project cost (EUR): 227984.41
EU funding (EUR): 227984.41
Participants: 1
Project status: CLOSED

First discovered and manufactured in Berkeley Radiation Laboratory in 1940, the isotope carbon-14 (C-14, also called radiocarbon) has since played a fundamental role in the development of biomedical sciences, human sciences and environmental sciences. This project aims to produce an up-to-date history of its first applications in Europe, by exploring the circulation of materials, instruments and techniques based on this isotope after World War 2. In particular, research will focus on three case studies of appropriation of isotopic tracing techniques, which will be approached from a transnational perspective: the use of C-14 techniques by molecular biologists, the use of radiocarbon in archeological dating and the use of carbon-14 in environmental sciences. The study of the use of similar techniques in different disciplines will allow for an analysis on interdisciplinary connections between fields, and also for a comparative study of the transfer and validation of these techniques among different research communities. Besides studying these methodological and epistemological questions, the project will result in a up-to-date chronology and a guide of sources on the history of nuclear sciences in Europe, as well as a repository of oral interviews to key actors in thsi field. The project will also pay attention to the public image of these researches in the public sphere, in relation to the campaign “Atoms for Peace” and the development of nuclear industry in Europe. In doing so, the project will develop new historiographical techniques related to the use of the press as a source in the history of science.

Keywords: history of science,history of technology,social shaping of technology,contemporary history of science,history of science communication,history of biomedical sciences,history of physical sciences
Heterometallic and mixed valence “Chirale magnetic bricks” in assembler of Single Molecule and Single Chain Magnets for nano-dimension magnetic materials. (CHIRALIX)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-IIF-2008, 2008)
Start date: 2010-02-01
End date: 2012-01-31
Duration (months): 24.0
Total project cost (EUR): 234448.33
EU funding (EUR): 234448.33
Participants: 1
Project status: CLOSED

The aim of this project is to develop new molecule based magnetic materials (SMM and SCM) using “chiral magnetic bricks”. The overall purpose of the proposal is to expand the researches toward new compounds with polynuclear and nano-dimensional character as well as with peculiar magneto-chiral properties. The following main research topics will be developed as parts of this project: i) synthesis of new bicompartmental chiral Schiff and Mannich-based ligands; ii) template synthesis of “chiral-magnetic bricks” with SMM behaviour; iii) assembly of “chirale magnetic bricks” by using the free radicals to yield polynuclear heterometallic and mixed valence compounds; iv) understanding the impact of chirality in magnetic properties of building block units and their multidementional networks.

Keywords: structural chemistry,inorganic chemistry,magnetochemistry,heterometallic compounds,molecular chemistry