Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Safe System for radical improvement of road safety in low- and middle-income African countries (AfroSAFE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Safe, Resilient Transport and Smart Mobility services for passengers and goods
Action type: Research and Innovation actions
Countries involved: Sweden,Norway,Ghana,Zambia,Denmark,Tanzania, United Republic of,Netherlands
Call: Radical improvement of road safety in low and medium income countries in Africa (HORIZON-CL5-2021-D6-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 4000000.0
EU funding (EUR): 4000000.0
Participants: 11
Project status: SIGNED

The primary objective of the AfroSAFE project is to make a significant progress in propagation of the Safe System modus operandi within the road safety work context in African countries. This is reached by exposing the local practitioners and decision makers to the state-of-the-art knowledge and practices within road safety management based on Safe System principles, as well as supporting them by sharing necessary knowledge, tools and methods for road safety improvement—adjusted to the African conditions and in tight cooperation with the local actors. More specifically, this is reached through mapping of the existing regulations, procedures, methods and tools within all five pillars of road safety (management, safe infrastructure, safe vehicles, safe road users and post-crash care), development of the recommendations for improvements and running a series of pilots and demonstrations to illustrate these recommendations in action. In these activities, the problems and needs of the vulnerable road users will receive particular attention. Another focus area for the AfroSAFE project is capacity building through education of the local educators in all areas relevant for road safety. Together with them, the current curriculums are revised, new educational programmes created, and an educational platform—a virtual centre of excellence—will be created.

Keywords: africa,traffic safety,safety management,safe system,vision zero
Evolvable and rapidly adaptable monobodies: a broad-spectrum antiviral platform (EvaMobs)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: Portugal,Netherlands,Switzerland,Spain,Ireland,Belgium,Croatia,Germany
Call: Pandemic preparedness and response: Broad spectrum anti-viral therapeutics for infectious diseases with epidemic potential (HORIZON-HLTH-2023-DISEASE-03, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 7999838.75
EU funding (EUR): 7999838.75
Participants: 12
Project status: SIGNED

With progress in globalization, expansion of human populations into natural habitats, and aggravation of climate change comes an increased risk of viral outbreaks. As demonstrated by the COVID-19 pandemic, not being prepared for such events has devastating consequences on public health, society and the economy. EvaMobs will improve preparedness of the European Union (EU) for the next viral outbreak(s) of pandemic potential by developing a platform for the discovery, development, production and validation of evolvable and rapidly adaptable antivirals. These innovative medicines will be based on small human-derived proteins called monobodies (Mobs). As Mobs can be engineered to have high binding affinity for virtually any viral protein, this platform can be easily adapted to a broad range of viruses, including newly emerging viruses and viral variants. To demonstrate the capacity of this platform it will first be applied to four pathogenic viruses with epidemic and/or pandemic potential: Influenza A, SARS-CoV-2, respiratory syncytial virus, and Zika virus. Deep-learning and computational design tools will allow generation of tailor-made Mobs with cryo-EM elucidating the molecular details of their binding interaction. Simple bacterial expression of Mobs, the development of a semi-automated high-throughput screening platform for evaluation of the Mobs’ stability and target affinity and streamlined in vitro and in vivo preclinical validation, will allow rapid development and selection of stable and potently neutralizing candidates. The Mob with the best preclinical indicators will then be tested in a phase I clinical trial after implementing a stable formulation and GMP production. The optimized platform can then be adapted to other viruses. Therefore, EvaMobs provides an innovative, robust and flexible platform for antiviral biologics development as well as a diverse portfolio of validated drugs, strengthening the EU’s pandemic preparedness.

Keywords: biopharmaceutical,monobody,computational design,preclinical validation,
Re-imagining Activism, Communication and Trajectories of Participation in the Global South (REACT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: United Kingdom,Brazil,Mexico,South Africa,Colombia
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 2436327.0
EU funding (EUR): 2436327.0
Participants: 5
Project status: SIGNED

We live in a time of endemic uncertainty and accelerating socio-economic exclusion. The collapse of the extractivist ideology of the neoliberal model of development has led to needs for other worldviews. Young people in the Global South are particularly impacted by the socio-economic consequences, affecting their ability to control their livelihoods. This is indicated by high unemployment, gender and job market inequalities, and the decline of living standards despite general economic growth. REACT emerges as an ambitious, feasible project. The ambition is empirical, methodological and theoretical. REACT uniquely focuses on sourcing everyday activism outside of conventional activist spaces. A qualitative study of 300 youth across 5 cities combined with a survey (12.000) from 20 cities will generate insights on how young people negotiate and act upon their life circumstances. REACT applies a critical-creative pedagogy to foster critical hope via artistic expression, scenario building, urban manifestos, networking and cultural encounters across the Global South. Uncovering individuals’ everyday practices of activism generates insights about the formation of subjectivities in urban contexts, practices of communication in everyday life, perceptions and forms of activism, connects hope with citizenship, and individual action with collective action. These elements are deeply intertwined, hence the need for an interdisciplinary framework. Embedded in communication for social change, and drawing on cultural studies, urban studies, critical pedagogy and critical development studies, REACT will develop a novel interdisciplinary theory for the study of COMmunication, PArticipation and Social Change (COMPAS). REACT’s ambition is also geographical and epistemological; Conducting a study of young people across the geographical Global South can amend the cognitive injustice seen in the imbalance of knowledge production about youth, communication and social change.
International Clinical Validation of Radiomics Artificial Intelligence for Breast Cancer Treatment Planning (RadioVal)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: Spain,Netherlands,Greece,Italy,Portugal,Finland,Sweden,Poland,Croatia,Austria,Türkiye,Argentina,Egypt
Call: Clinical validation of artificial intelligence (AI) solutions for treatment and care (HORIZON-HLTH-2021-DISEASE-04, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 5838576.0
EU funding (EUR): 5838576.0
Participants: 16
Project status: SIGNED

Breast cancer is now the most common cancer worldwide, surpassing lung cancer in 2020 for the first time. It is responsible for almost 30% of all cancers in women and current trends show its increasing incidence. Neoadjuvant chemotherapy (NAC) has shown promise in reducing mortality for advanced cases, but the therapy is associated with a high rate of over-treatment, as well as with significant side effects for the patients. For predicting NAC respondents and improving patient selection, artificial intelligence (AI) approaches based on radiomics have shown promising preclinical evidence, but existing studies have mostly focused on evaluating model accuracy, all-too-often in homogeneous populations. RadioVal is the first multi-centre, multi-continental and multi-faceted clinical validation of radiomics-driven estimation of NAC response in breast cancer. The project builds on the repositories, tools and results of five EU-funded projects from the AI for Health Imaging (AI4HI) Network, including a large multi-centre cancer imaging dataset on NAC treatment in breast cancer. To test applicability as well as transferability, the validation with take place in eight clinical centres from three high-income EU countries (Sweden, Austria, Spain), two emerging EU countries (Poland, Croatia), and three countries from South America (Argentina), North Africa (Egypt) and Eurasia (Turkey). RadioVal will develop a comprehensive and standardised methodological framework for multi-faceted radiomics evaluation based on the FUTURE-AI Guidelines, to assess Fairness, Universality, Traceability, Usability, Robustness and Explainability. Furthermore, the project will introduce new tools to enable transparent and continuous evaluation and monitoring of the radiomics tools over time. The RadioVal study will be implemented through a multi-stakeholder approach, taking into account clinical and healthcare needs, as well as socio-ethical and regulatory requirements from day one.

Keywords: breast cancer,treatment planning,radiomics,artificial intelligence,clinical validation,trustworthiness
Islands in the Stream: Climate-related Disasters and the Rhythms of Caribbean Music (I-STREAM)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-11-01
End date: 2029-10-31
Duration (months): 60.0
Total project cost (EUR): 1302500.0
EU funding (EUR): 1302500.0
Participants: 2
Project status: SIGNED

For decades, Caribbean musics have seen unparalleled global popularity, becoming key to the region’s tourism economy. Yet today, Caribbean live music scenes are in peril, reeling from recurring climate-related disasters. In light of music’s centrality to Caribbean tourism economies and cultural life and the increasing frequency and severity of climate related events, the stakes for understanding the role of live music in recovery processes is particularly high. Focusing on three urban contexts - San Juan (Puerto Rico), Kingston (Jamaica), and Havana (Cuba) - I-STREAM will investigate the impact of climate disaster on the long-term rhythms of musical activity – the location, frequency and content of live music in the Caribbean. Responding to methodological challenges affecting research in disaster contexts – such as the displacement of local population and cultural spaces – I-STREAM will integrate ethnographic research with analysis of online concert videography - videos taken in the course of performance and uploaded to online platforms – to analyze musical and geo-temporal data on processes of change and recovery following the occurrence of climate-related disasters. This will complement participatory on-site research and input from local stakeholders (concert goers, musicians and industry professionals) and will shed new light on the changing frequency and diversity of live music performances, a crucial index of displacement and touristification following major disasters in contexts - such as the Caribbean - where music holds a fundamental role in sustaining the economy and in the lives of local inhabitants.

Keywords: caribbean music,tourism,climate related disaster,long term rhythms,music scenes,climate migration
Improving social competences of virtual agents through artificial consciousness based on the Attention Schema Theory (ASTOUND)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Spain,France,Germany
Call: Awareness Inside (HORIZON-EIC-2021-PATHFINDERCHALLENGES-01, 2021)
Start date: 2022-12-01
End date: 2025-11-30
Duration (months): 36.0
Total project cost (EUR): 3330897.5
EU funding (EUR): 3330897.5
Participants: 5
Project status: SIGNED

In the last decade, deep learning algorithms have enabled AI systems to perform a series of tasks, like speech and image recognition, as well as or better than humans. However, this technology is not going to be enough to deliver human-level intelligence without consciousness. Without understanding the subjective awareness element, it may be impossible to build AI that has a human-like ability to focus its computational resources and intelligently control that focus and interact with people in a socially competent manner. ASTOUND proposes an Integrative Approach For Awareness Engineering to establish consciousness in machines. The approach consists of an AI architecture for Artificial Consciousness based on the Attention Schema Theory (AST), a novel approach to social cognition that reconciles some of the current most debated cognitive neuroscience theories of consciousness. According to the AST, the brain constructs subjective awareness as a schematic model of the process of attention, suggesting that an information-processing machine could attribute consciousness properties to others in a similar way. The AST-based architecture proposed by ASTOUND will combine an Attention Mechanism provided by the attentional layers in a deep neural architecture and a Long Term Memory module allowing interplay between internal and external stimuli (data) with an Attention Schema that will determine empathic and trustworthy decision-making. ASTOUND will first implement this architecture into a virtual conversational agent (i.e. chatbot) to verify the hypothesis that an artificial consciousness based on AST will improve performance in a task of natural language understanding. ASTOUND will provide insights into consciousness that are concrete enough, and mechanistic enough, that engineers can build upon it to facilitate future technologies. The study has the potential to be a toolbox for the construction of an EIC Portfolio in conscious AI.

Keywords: awareness,consciousness,conversational agent,chatbot,attention schema theory,global workspace theory,artificial intelligence,neuroscience,cognitive science,computer science
Quantum Excellence Centre (QUEX)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: European High Performance Computing
Action type: Research and Innovation actions
Partnership: EUROHPC (JU-JTI)
Countries involved: Netherlands,Denmark,Ireland,Germany,Spain
Call: European Quantum Excellence Centres (QECs) in applications for science and industry (HORIZON-EUROHPC-JU-2023-QEC-05, 2023)
Start date: 2025-04-15
End date: 2029-04-14
Duration (months): 48.0
Total project cost (EUR): 9999650.0
EU funding (EUR): 4999824.97
Participants: 11
Project status: SIGNED

In this proposal we will set up the Quantum Excellence Centre (QUEX) as a one-stop-shop for potential end-users of quantum technology. To take full advantage of the emerging EuroHPC quantum computing infrastructure, it is essential that a Centre of Excellence exists, where top researchers within Europe can collaborate on world-changing quantum applications, boost the European quantum ecosystem, create a virtual (and possibly physical) forum for end-users to share experiences, express requests for the eco-system etc., and focus the development on the needs of academic and industrial end-users. To reach the objectives above we will follow two main strategies: 1. Firstly, we focus on the needs of the end-users in the development. We aim to develop a co-creation process where we join various state-of-the-art open-source tools to obtain a high quality ‘modus operandi’ in all steps of the procedure from defining the problem/challenge all the way to test and validation. With QUEX developed software we will use the EOSC-quantum hub to distribute software modules, packages, and libraries. 2. Secondly, the training and skills development shape an important part of the proposal, offering customizable training programs from excellent quantum experts to enhance skills and knowledge transfer within the quantum community. Skills development is an area where the consortium has immense experience – it includes educational modules in the quantum area as well as intensive experience giving summer schools, PhD-courses, conferences etc. This will be expanded with online material of types like videos, slides, notes/reports, exercises, solutions etc. Establishing QUEX will accelerate the adaptation of quantum computing within Europe, allow European industries to be one of the first to reap the benefits of quantum computing, and ensure strategic autonomy for the EU on quantum computing.

Keywords: centre of excellence,customer journey,end users,workflows,software modules,packages and libraries,technology uptake,eosc qcs node,industry,science,hybrid quantum computing,training
Genetic REcombination and MAting in Mamiellophyceae (GREMA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-17
End date: 2024-10-16
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: CLOSED

Phytoplankton is responsible of almost the half of earth’s primary production. Among the different components of the phytoplankton, there is an important group of picosized green algae (between 0.8 and 3um), the Mamiellophyceae, that is ubiquitous in the sunlit ocean and can reach high abundances in coastal environments. The first population genomics study of the Mamiellophycean species Ostreococcus tauri, revealed indirect evidences of recombinant events and the presence of two different mating types (M+ and M-), which led to the description of these two mating types in another three Mamiellophycean species. However we do not know whether this candidate mating-type structure is conserved throughout earlier diverging Mamiellophyceaen lineages. Neither do we know the relative frequency of the two mating types in natural communities and which environmental factors influence mating and recombination. Therefore, the major aim of this proposal is to elucidate the evolution of mating types and the prevalence of recombination across natural populations in ecologically relevant phytoplanktonic species (Mamiellophyceae), including the estimation of environmental effects in mating. To address this, I will use a multidisciplinary approach taking advantage of an original set of genomic datasets (population genomics data, new genomic sequences and metagenomic data from natural communities) and experimental tools, which will allow me to contribute to solving an important knowledge gap in the life cycle of Mamiellophyceae. Specifically, I will focus in identifying the prevalence of recombination in two closely related species of Otreococcus, capture the ecology and evolution of mating types across Mamiellophyceae and detect the abiotic and biotic factors that affect mating in O. tauri. For the latter, I will take advantage of genetic transformation techniques to select recombinant cells.

Keywords: recombination,mating,mamiellophyceae,green algae,marine microbes
The Filmmaker in Brazilian Indigenous Communities: the impacts of a new social and political position (TFBIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-09-01
End date: 2026-07-31
Duration (months): 35.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

This project combines approaches from anthropology and film studies to investigate how the systematic use of audiovisual equipment and techniques has contributed to the creation and consolidation of the position of ‘the filmmaker’ in Brazilian indigenous communities. Designed in collaboration with indigenous filmmakers, it will study three communities from different parts of Brazil, each with different histories and traditions of filmmaking - the Kuikuro, the Maxakali, and the Guajajara. In undertaking these studies, BFIC proposes an expanded and comparative analysis of the filmmaker's consolidation as a new social-political position that holds great prestige alongside traditional roles like the community leader, the health agent, the shaman, and the teacher. Around 90% of Brazilian indigenous communities now have their own filmmaker. They are responsible for transmitting technical audiovisual knowledge to younger generations; for cultural registration; and for disseminating information to mainstream media. However, it is also undeniable that indigenous production has gone beyond the limits of ‘ethnographic film’ and occupies a place in wider cinematographic culture. The filmmaker is therefore central to the exchange of symbolic production, and their work contributes to subverting and decolonising commonly held visual notions of what it is to be indigenous. The open access journal articles and collaborative short film produced by this project will explore the consolidation of the position of ‘filmmaker’ in detail for the first time. Alongside a range of dissemination activities targeted at academics and an interested general public, it will also hold audiovisual workshops in indigenous villages to directly strengthen ties between the Kuikuro, Maxakali and Guajajara communities. In doing so, BFIC will help to reinforce the struggle of indigenous peoples for the right to land, life and the preservation of the environment.

Keywords: indigenous communities visual anthropology film studies