Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Re-designing the value and supply chain of water and minerals: a circular economy approach for the recovery of resources from saline impaired effluent (brine) generated by process industries (ZERO BRINE)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Enabling the transition towards a green economy and society through eco-innovation
Action type: Innovation actions
Countries involved: Italy,Spain,Spain,Spain,Germany,Spain,Belgium,Greece,Poland,Belgium,Türkiye,Sweden,Netherlands,Netherlands,Netherlands,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Systemic, eco-innovative approaches for the circular economy: large-scale demonstration projects (H2020-CIRC-2016TwoStage, 2016)
Start date: 2017-06-01
End date: 2021-11-30
Duration (months): 54.0
Total project cost (EUR): 11033651.34
EU funding (EUR): 9992209.11
Participants: 25
Project status: CLOSED

This project aims to facilitate the implementation of the Circular Economy package and the SPIRE Roadmap in various process industries by developing the necessary concepts, technological solutions and business models to re-design the value and supply chains of minerals (including magnesium) and water, while dealing with present organic compounds in a way that allows their subsequent recovery. This is achieved by demonstrating new configurations to recover these resources from saline impaired effluents (brines) generated by process industry, while eliminating wastewater discharge and minimising environmental impact of industrial operations through brines (ZERO BRINE). The project will bring together and integrate several existing and innovative technologies aiming to recover end-products of high quality and sufficient purity with good market value. It will be carried out by large Process Industries, SMEs with disruptive technologies and a Brine Consortium of technology suppliers across EU, while world-class research centres ensure strong scientific capacity and inter-disciplinary coordination to account for social, economic and environmental considerations, including LCA. A large scale demonstration will be developed in the Energy Port and Petrochemical cluster of Rotterdam Port, involving local large industries. Two demo plants will be able to treat part of the brine effluents generated by one process industry (EVIDES), while the waste heat will be sourced by neighbouring factories. The quality of the recovered end-products will be aimed to meet local market specifications. The involvement of representatives covering the whole supply chain will provide an excellent opportunity to showcase Circular Economy in Rotterdam Port, at large scale. Finally, three large-scale pilot plants will be developed in other process industries, providing the potential for immediate replication and uptake of the project results after its successful completion.

Keywords: brine effluent,water recovery,minerals recovery,salt,magnesium recovery,waste heat,industrial symbiosis,circular economy,closing the loop
Supporting public sector's capacity and leadership in decarbonising Europe's building stock, through the development of a multi-level renovation impact framework (BUILD UPON2)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Germany,Ireland,Italy,Spain,Türkiye,Croatia,Hungary,Poland,Belgium,United Kingdom
Call: Supporting public authorities to implement the Energy Union (H2020-LC-SC3-EE-2018, 2018)
Start date: 2019-06-01
End date: 2021-11-30
Duration (months): 30.0
Total project cost (EUR): 1819655.0
EU funding (EUR): 1731755.0
Participants: 10
Project status: CLOSED

BUILD UPON2 proposes to address one of the main barriers stopping proper public management, and consequent upscaling of Deep Energy Efficiency Renovation: the lack of an adequate, widely shared Impact Framework. Buildings are one of the biggest contributors to climate change in Europe and account for over 40% of the EU’s final energy demand and 36% of CO2 emissions. To meet EU’s energy efficiency targets for 2020 and 2030 and long-term goal under the revised EPBD to decarbonise it’s building stock by 2050, renovation becomes crucial, and its rate needs to increase to at least 2-3% per annum. National Renovation Strategies under the EED aimed to accelerate the rate of renovation, however these have not proved effective. The 2018 recast of the EPBD strengthens the role of these Strategies and obliges MS to set out a roadmap to decarbonised building stock by 2050, supported by a suite of measurable progress indicators and milestones. BUILD UPON2 proposes to work with local, national and European stakeholders to create a Multi-Level Renovation Impact Framework that contains a suite of milestones and measurable progress indicators for building renovation strategies, integrating data and insights from the city level. This Framework will serve as a tool for Cities in delivering the EPBD and ensure that local initiatives are aligned with national and European policies. A methodology will be developed to indicate how the Framework reporting system can be integrated into Sustainable Energy Actions Plans (SECAPs), how to use the Framework and how data to support the indicators will be collected and used. The Framework will be tested with 8 pilot cities and the results of this testing phase will be used to update the Framework and create policy recommendations, ensuring that the Framework can be replicated across Europe and help local, regional and national authorities deliver on European energy efficiency goals. The Project Consortium ascertains a successful delivery.

Keywords: secaps,epbd,multi level renovation impact framework,cities,local authority,capacity building,implementation,energy union,renovation rates,deep renovation
Personalised multimedia digital consultation to revolutionise the doctor-patient consultation process. (Anatomus)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Ireland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-12-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Anatomus is a software platform that enables personalised and recorded doctor-patient consultations, which enhance patient education and increase treatment plan adherence. Seal of Excellence recipient in February 2019, eMedia is an award winning medical multimedia software design company, registered and based in Ireland, specialising in 3D medical education software - most notably, creators of the Pocket Anatomy, the company has developed Anatomus, a software platform that is working on using interactive 3D anatomy to improve the overall doctor-patient communication process. The doctor-patient consultation lasts on average 10 minutes in Europe, resulting, in the patient, remembering only 14% of what was discussed. According to the World Health Organisation (WHO), “in developed countries, adherence among patients suffering chronic diseases averages only 50%”, which leads to higher hospitalisation, higher costs (€125billion/year), higher social impact and premature deaths (200,000/year). Based on these challenges, Anatomus aims to help patients understand and remember what the doctor said by using interactive multimedia visualisations of common illnesses on mobile devices in the doctor's office, which can be shared with patients for improved understanding, recall, and treatment plan adherence.

Keywords: elearning,patient education,patient centred design
Gas Sensors for future Ultra Low NOx Emission Legislation – Euro 7 (SiC-MOSFET)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-09-01
End date: 2020-02-29
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Air pollution remains one of the biggest environmental risks to public health in Europe and causes an estimated 422 000 premature deaths per year. Nevertheless, many European countries are still failing to meet air quality standards. Poor human health, heart and lung diseases, reduced labour productivity are all unnecessary consequences that result in additional expenditures for health, environment and penalty payments for excess emissions. SenSIC attempts to address these challenges by offering its gas sensors for harsh environments. SenSiC’s gas sensor technology has been developed over 20 years of research and is based on the use of Silicon Carbide (SiC) for semiconductors. Unlike existing sensors on the market, the SenSiC sensors offer full functionality in very high temperatures (up to 650C) and harsh environments such as domestic heating systems, process industry, automotive and marine engines etc. Because the sensor semiconductor chip is placed directly in the exhaust gases (in situ), there is no extra cooling delay as with other sensors, and therefore the response is quick. A single sensor unit can detect multiple gases as well as pressure. Our technology has exceptional sensitivity in very low gas concentrations with a proven long term performance. By measuring gas concentrations, e.g. for NH3, NOx, O2 and CO, it is possible to control the combustion and by that reduce harmful emissions. This leads to a cleaner environment and higher quality of the air we all breath. The key objective of our project is to transform an initial business plan into a robust strategy for international commercialization and to prepare for a Phase 2 development. With this objective in mind, our Phase 1 project will focus on a more precise market evaluation and developing a plan for future demonstration activities, including reference user and application selection. Through the market part of the feasibility assessment, we will further optimize our go-to-market strategy

Keywords: gas sensor technology,reduced emissions,energy efficiency,mosfet,silicon carbide
Transforming the limits of resolution by utilizing quantum information (QRES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Israel
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-04-01
End date: 2024-03-31
Duration (months): 72.0
Total project cost (EUR): 1820475.0
EU funding (EUR): 1820475.0
Participants: 1
Project status: SIGNED

Quantum sensing(QS) and metrology exploit physical laws governing individual quantum systems, and correlations between systems, to measure a physical quantity. Recently, an appreciation of the vast potential for a variety of applications, including magnetic and electric fields, pressure and temperature sensors, and imaging at the nanoscale, has positioned QS at the centre of quantum science and technology. QS is a rapidly growing field, with the most common platforms being spin qubits, trapped ions and flux qubits. The main resource for quantum sensing is coherence, the definite phase relation between different states. This phase can only survive until the coherence time, which limits the sensitivity of quantum sensing. For quantum sensing the decay time T1 is believed to be the ultimate limit. QS targets a broad spectrum of physical quantities, of both static and time-dependent types. While the most important characteristic for static quantities is sensitivity, for time-dependent signals it is the resolution, i.e. the ability to resolve two different frequencies. This is the central subject of the proposed research. Quantum computing has been shown to be feasible thanks to the realization that error correction can be applied to quantum operations in a fault-tolerant way. This opens up the possibility to realize quantum operations at very precise levels of accuracy and resolution. In my planned research I will address the issue of whether this extraordinary accuracy, when combined with robust time keeping methods, can be exploited to enhance quantum sensing in general - and resolution in particular. For this purpose, I will design protocols that far surpass the state-of-the-art, with the final goal being to overcome the T1 limit. Besides the insights gained for quantum theory, the research will result in detailed proposals for experiments to be realized by experimental groups investigating Nitrogen-Vacancy color centers in diamond and trapped-ion quantum logic.

Keywords: quantum sensing,nv centres in diamond,trapped ions
Advancing a novel peptide-based therapeutic for pancreatic cancer (FIBROHALT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Netherlands
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Pancreatic cancer is a devastating disease with a median 5-year survival rate of 3-5%. One explanation for the dismal prognosis is the failure of many chemotherapies. Pancreatic tumor cells stimulate neighbouring non-tumor cells (stromal cells) to join and grow around them. This stroma forms a fibrous matrix that promotes 1) aggressive tumor growth, 2) distant metastasis, and 3) form a barrier to chemotherapy and drug delivery. There is a high need to enhance the success of pancreatic cancer treatment by intensively pursuing strategies that target the tumor stroma. We are developing a novel peptide-based drug (AV3), that targets and reduces tumor stroma in pancreatic cancer, and potentially in other fibrosis-associated cancers. We have demonstrated that AV3 reduces fibrosis (>50%) and enhanced the efficacy of chemotherapy in clinically relevant patient-derived xenograft models (achieving up to 80% tumor regression). Thus, our novel peptide has the potential to become a breakthrough add-on to chemotherapy in the treatment of pancreatic cancer. We are a biopharmaceutical company, spun-out in 2016 by the University of Twente. Our mission is to develop novel, targeted, peptide-based drugs to treat pancreatic cancer and other fibrosis-associated cancers and diseases with high unmet medical needs. The management team consists of its pioneering scientific founder and inventor of the technology Prof. Jai Prakash (CEO) and an experienced entrepreneur and drug developer Dr. Bart Metselaar (COO). The FIBROHALT project will (1) create a clear overview of the clinical opportunity for AV3 in pancreatic cancer, 2) develop a strategy to position the drug in the pancreatic cancer market, and (3) create an optimal development strategy, including a de-risk plan for future clinical studies. We will pursue a co-development or licensing deal for AV3 with a pharmaceutical company which will perform late-stage clinical development, obtain EMA/FDA approvals, market and sell AV3.

Keywords: fibrosis stroma pancreatic cancer chemotherapy add on peptide based drug
Clean Energy from Hydrogen-Metal Systems (CleanHME)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Emerging themes and communities
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Italy,Germany,Poland,Sweden,Slovenia,Belgium,Slovakia,France,France,France,France,United States,Canada
Call: FET Proactive: emerging paradigms and communities (H2020-EIC-FETPROACT-2019, 2019)
Start date: 2020-08-01
End date: 2024-07-31
Duration (months): 48.0
Total project cost (EUR): 5678597.5
EU funding (EUR): 5509447.5
Participants: 17
Project status: SIGNED

The main aim of the CleanHME proposal is to develop a new, clean, safe, compact and very efficient energy source based on Hydrogen-Metal and plasma systems, which could be a breakthrough for both private use as well as for industrial applications. The new energy source could be employed both as a small mobile system or alternatively as a stand-alone heat and electricity generator. Hydrogen-Metal Energy (HME) is gained when hydrogen reacts with some metals under slightly increased temperature and pressure. First experiments have shown that the total heat energy produced exceeds by many orders of magnitude the chemical energy and strongly depends on applied active metallic materials and gas conditions in special reactors. Furthermore, accelerator experiments performed at higher energies of hydrogen isotopes have shown that the reaction rates can be enhanced by many orders of magnitude due to so-called electron screening effect if metallic samples with special nanostructures or crystal lattice defects are utilized. Thus, the main objectives of our proposal are to elaborate a comprehensive theory of HME phenomena and optimize the choice of the best materials for energy production in hydrogen-metal systems by combining accelerator and gas-loading experiments and to improve the reactors design leading to higher and stable energy production. We plan to construct a new compact reactor to test the HME technology during the long-term experiments and increase its technology readiness level. The proposed solutions have a potential to be a breakthrough for the power supply industry and present a solution for a carbon-free technology contributing to the climate and natural environment protection. To ensure it, we would like to build a broad multidisciplinary European consortium of scientific institutions, start-ups and commercial companies spread over 9 European countries, collaborating with leading scientists in USA and Canada.

Keywords: hydrogen metal energy sources
SaTEllyte synthetic Aperture radar interferometry to model Dam stabilitY (STEADY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-05-01
End date: 2019-04-30
Duration (months): 24.0
Total project cost (EUR): 175419.6
EU funding (EUR): 175419.6
Participants: 1
Project status: CLOSED

Analyses of surface deformation can help to define the evolution of areas, structures and infrastructures menaced by hazardous phenomena. To this end, space-borne Synthetic Aperture Radar (SAR) data provides direct measures of surface movements. Specific techniques to handle SAR data have been recently applied to monitor not only natural hazardous phenomena, such as earthquakes, subsidence and landslides, but even structural health of buildings and infrastructure. The large spread of these techniques is supported by the non-invasiveness of radar signals, the possibility to cover vast areas and the availability of a large database of data acquired since the ‘90s, despite they do not give any indication about the triggering factors and the strain source or the tensile condition of a structure. STEADY Project (SaTEllyte synthetic Aperture radar interferometry to model Dam stability) is aimed to use SAR data to monitor dam structural health and, even more, to apply an innovative approach, exploiting deformation fields as a starting point to re-create a simplified analytical model, providing preliminary hints about the stress-strain status of the dam in a short time if compared with traditional finite element models. The relevance of this process emerges when environmental or logistic conditions do not allow to monitor dams through traditional geodetic and numerical techniques. In such cases, results obtained from SAR data combined with an analytical model constitute a reliable diagnostic tool of dam structural health to avoid any extraordinary failure that may lead to loss of lives. The method will be tested on an emblematic real case, the Mosul dam, facing the following goals: (i) analysis of satellite SAR data available over the area, (ii) identification of an analytical model to reproduce dam deformation behaviour and tensile condition, (iii) implementation of a semi-automatic tool to perform numerical simulations, applicable to further cases.

Keywords: remote sensing,sar interferometry,dam model,damage assessment
ANGIO-tracer for immuno-PET imaging: a stratification and monitoring tool for anti-angiogenesis treatment (ANGIO-IMAGE)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Netherlands
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-1-2015, 2015)
Start date: 2016-05-01
End date: 2016-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

AngioTarget will introduce an angiogenesis imaging agent (ANGIO-tracer) to stratify patients prior to anti-angiogenic therapy (AAT). This proposal is focussing on colorectal cancer (CRC) and will try to save 45,000 stage II/III CRC patients from undertreatment and 60,000 stage IV patients from unnecessary treatment in Europe each year. CRC is one of the most common cancers world-wide. AAT is a widely used and promising approach to restrict growth and progression of all angiogenesis-dependent malignancies. However, this expensive anti-cancer strategy is challenged by low response rates, inadequate efficacy and resistance2. Currently, there is no tool available to stratify patients prior to AAT or monitor response to therapy. The first approved and commercially most successful anti-angiogenic drug is Avastin (Bevacizumab), accounting for over €7 billion in annual sales. As a first phase towards global acceptance of ANGIO-tracer as a standard for stratification and monitoring in AAT of cancer, AngioTarget will focus on the utility of ANGIO-tracer in determining and monitoring Avastin treatment strategies in CRC. This will ensure that all CRC patients receive optimal care and responders can benefit from AAT while non-responders are spared from ineffective treatment. Commercial introduction in Europe of ANGIO-tracer as a stratification tool in CRC will: - Improve patient outcome by enabling optimal treatment of over 18,700 stage II/III and 14,000 stage IV patients within 5 years, reducing healthcare costs related to ineffective Avastin administration with €1.8 billion in 2024 - Increase growth and competitiveness of AngioTarget, including cumulative sales of over 261,000 units (total revenue €78 million) within 5 years and a cumulative net profit of >€30 million - Open up new markets for ANGIO-tracer (e.g. lung, prostate, breast cancer)

Keywords: angiogenesis,cancer,anti angiogenic therapy,pet tracers,imaging