Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Developing the sustainable market of residential Mediterranean solid biofuels. (Biomasud Plus)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Alternative fuels and mobile energy sources
Action type: Coordination and support actions
Countries involved: Spain,Italy,Austria,Spain,Croatia,Türkiye,Greece,Slovenia,Portugal
Call: Market uptake of existing and emerging sustainable bioenergy (H2020-LCE-2015-3, 2015)
Start date: 2016-01-01
End date: 2018-12-31
Duration (months): 36.0
Total project cost (EUR): 1971610.0
EU funding (EUR): 1971610.0
Participants: 11
Project status: CLOSED

The Biomasud certification system of the quality and sustainability of solid biofuels (http://biomasud.eu/), was created within the BIOMASUD interreg IV project in 2013 with the aim of covering all typical Mediterranean biomass resources used as solid biofuels in small and medium heating installations: domestic, commercial, institutional etc. The label is owned by several partners established in Spain, Portugal and France.Presently, the label includes wood chips and pellets, olive stones and some types of nut shells. Also within Biomasud project, a GIS tool that provides information about sustainable biomass resources and costs available in different Mediterranean countries was updated and upgraded with new information about agroindustrial residues and pellets production and producers Presently, some solid biofuel companies are already producing under the Biomasud quality label in Spain, and others have also shown the interest to adopt it in Spain and Italy, but there is a strong need for development of the label along the whole Mediterranean area where the biomasses and solid biofuels under the label are widely produced and used in the domestic sector market out of any standards. Moreover, there is also a need to extend the label to new biomasses that are used in the Mediterranean area and which are not covered by the label, this making therefore more difficult their appropriate combustion in stoves or small-medium size boilers. Finally, it is also important to mention that, in order to improve the label, a research is needed to develop new and/or review the existing Biomasud label analytical limits and sustainability tools along the value chain, including, the GHG calculation procedure. In the described context, the overall goal of the project is the improvement, dissemination and market development of the Biomasud label in order to promote the sustainable use of the Mediterranean autochthonous solid biofuels in the domestic sector.

Keywords: solid biofuels,sustainability,quality,certification sytem,mediterreanean,olive stones,wood chips,dry fruit shells
Carlo Goldoni and Europe's New Opera Theatre (GoldOpera)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-03-01
End date: 2018-07-31
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

Venetian playwright Carlo Goldoni (1707-1793), famous for his ‘reform’ of comic theatre, was also a prolific librettist. Research has focused largely on Goldoni’s early texts for music, while the libretti written during his mature years have remained overshadowed by his most famous comedies. With growing attention to interdisciplinary studies, the time is now ripe for these later texts for music and the operas drawn from them to be brought to light, because, most importantly, precisely through these libretti Goldoni became a pioneer in the creation of the 'dramma giocoso,' a new genre of opera that would span a long legacy throughout Europe, all the way to the works of W.A. Mozart and Lorenzo Da Ponte. The goal of this project is the recovery and analysis of operatic renditions created from the innovative drammi giocosi by Goldoni, today nearly forgotten, to finally supply a comprehensive picture of the interaction between text, music, and theatre that fueled the radical evolution of Classical opera in the later 18th century. The study of these selected works will also yield a more detailed map of the artistic collaborations and diffusion of this new genre on an international scale. On a broader horizon, this project ultimately aims to create the basis for the restoration, publication, and performance of historical opera scores that have vanished from the traditional repertoire. These operas will become a source of new discoveries in both literary and musical fields, and their restoration through performance with the involvement of young musicians and scholars in conservatories and universities will not only render just merit to Goldoni for his innovations in opera theatre, but most importantly will bring to a larger public new knowledge of a form of art that had a global impact, and therefore a deeper understanding of our shared cultural heritage.

Keywords: multidisciplinary,comparative studies,history of theatre and opera,relationship of music and text
Game of Drones: Multimedia Streaming with Flying Terminals in Next Generation Mobile Networks (GAMODRONE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-07-01
End date: 2019-06-30
Duration (months): 24.0
Total project cost (EUR): 175419.6
EU funding (EUR): 175419.6
Participants: 1
Project status: CLOSED

The use of civilian unmanned aerial vehicles (UAV) that allow capturing and streaming video in real-time is steadily increasing. One of the reasons for such interest is that the use of drones, either single units or in swarms, is currently being considered for reconnaissance missions in emergency situations such as earthquakes, radiation leakage in nuclear power plants or in case of a terrorist attack. More challenging applications such as package delivery services are also being considered, in which data speed, reliability and video quality are of paramount importance. Another promising application for civil UAV’s is to help providing flexibility to beyond-5G networks. The main goal of the project (highest priority) is to study efficient adaptive video compression and streaming solutions for interactive and non-interactive omnidirectional video that allow making an efficient use of the available bandwidth while satisfying target delay and video quality requirements. In order to deal with the limited knowledge of the interference environment at the receiver side (which is a likely scenario for airborne terminals) I will study efficient interference management and multi-user detection techniques. In order to further optimize the bandwidth usage, the correlation between the information of different terminals (e.g., when two or more drones within a swarm are capturing partly overlapping panoramas) will be exploited, so that redundant information is kept at the minimum necessary. The secondary goal (lower priority) of the project is the study of how to efficiently exploit the unique UAV’s mobility characteristics to provide additional coverage in congested network areas. This will be carried out by capitalizing on the results of the main goal. In particular, the channel characterization and the interference management techniques studied in the context of video streaming will be adapted to the use of drones as 3D-mobile gap-fillers.

Keywords: video streaming,omnidirectional video,civil unmanned aerial vehicles,mobile gap fillers,delay limited communication
Blood Biomarker-based Diagnostic Tools for Early Stage Alzheimer’s Disease (BBDiag)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Italy,Spain,Italy,Spain,Germany,China,Denmark,United Kingdom,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2016, 2016)
Start date: 2017-01-01
End date: 2021-12-31
Duration (months): 60.0
Total project cost (EUR): 3434981.39
EU funding (EUR): 3434981.3899999997
Participants: 16
Project status: CLOSED

Alzheimer’s disease (AD) affects more than 7 million people in Europe and this figure is expected to double every 20 years. Despite intensive efforts, no disease-modifying treatments or preventive strategies are available. The lack of specific, sensitive and minimally invasive diagnostics to identify people with early-stage AD to be included in clinical drug intervention trials is among the main reasons for many notable trial failures. The main challenges in developing the required diagnostics are identification of AD biomarkers and development of their detection techniques. The complex and interdisciplinary nature of the research underlines the need for innovative training of a new generation of researchers in the field. BBDiag responds to such a need and establishes a much-needed ETN for blood based early-AD diagnostics to address these challenges. It brings together leading academic and industrial experts from five major consortia in Europe and uses their synergies to build a triple-i research & training platform with the required multidisciplinary expertise and cutting-edge technologies. BBDiag Fellows will be trained under the Vitae Researcher Development Framework innovatively combined with the BBDiag platform for gaining interdisciplinary scientific and transferable skills as well as personal quality, creative thinking and business mind-set. The ETN has a highly innovative research programme for the discovery of AD biomarkers, development of novel biosensing techniques and point of care tools, and for technological exploitation of the diagnostics. These advances will strongly support improved care provision and development of disease-modifying treatments and preventive strategies for AD patients. More importantly, BBDiag will deliver its first generation of 13 highly-skilled, creative and entrepreneurial Fellows, setting them on a path to successful careers in academia or industry to ensure that the medical and societal challenges imposed by AD are met.

Keywords: diagnostics of early stage alzheimer s disease,blood ad biomarkers,biosensors,electronics,preclinical,validation,clinical,trials,machine learning,business
Reconstructing human oral microbiome composition changes over the last 8000 years with proteomics and metagenomics approaches (PROMETEO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-09-01
End date: 2018-08-31
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

This project aims at reconstructing the evolution of human oral health in Northern Europeans, from the late Mesolithic to modern days, by genomics and proteomics investigation of: human ancient microbiota, human immune response proteins, and food remains preserved in mineralised dental plaque (archaeological dental calculus). The human microbiota is essential to maintain health, but capable of eliciting disease. Ecological shifts and imbalances (dysbiosis) of the oral microbiota can significantly impact health and cause severe forms of oral pathologies resulting in systemic disease at different body sites. Taxonomic reconstruction of ancient microbiomes and identification of which genes have been gained or lost in their genomes in connection with major lifestyle changes in human history will contribute to the development of more effective preventive and therapeutic approaches for this disease. The two main research objectives are: • Reconstruction of the evolution of the oral microbiome composition over the last 8000 years, and • Characterisation of the associated human immune responses. Genomic and proteomics biomolecular evidence will be retrieved from archaeological human dental calculus: a rich, but so far mostly neglected, source of ancient oral biomolecules. Ancient DNA and proteins extracted from archaeological dental calculus will be analysed using state-of-the-art proteomics and metagenomics approaches at the Centre for GeoGenetics, by high-resolution mass spectrometry and high-throughput DNA sequencing-by-synthesis methods. CGG recently led a high-profile study demonstrating the potential of this approach and will further develop this concept using approximately 80 Northern European samples from a wide chronological range. The Researcher’s skills in computational proteomics will be beneficial to ancient proteomics analysis, and his skills extended to the field of metagenomics.

Keywords: ancient dna,ancient proteins,ancient metagenomics,oral microbiome,mass spectrometry
BIM and GIS Integration for Archaeology: a new method for documenting field archaeology (BiGAr)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2024-09-30
Duration (months): 36.0
Total project cost (EUR): 269002.56
EU funding (EUR): 269002.56
Participants: 2
Project status: SIGNED

The BIGAr project aims to innovate archaeological research methodology developing a digital application to integrate representation software (Building Informative Model -BIM- and Geographical Information System -GIS-) to document the 4D nature of archaeological evidence as well as their traditional information (i.e. text or photography). This approach can be quicker and more complete than others currently used; it allows a higher degree of collaboration via Web as well as it provides a new frontier for spatial analysis and management of Cultural Landscape. So far, in archaeology, the use of BIM is only applied to architectural analysis and never integrated with GIS. Thus, I will use innovative geospatial environment, developing a new digital workflow of integration GIS and BIM, for managing archaeological data, collected in field works as excavations and surveys. To achieve this target I will develop a dedicated application based on an original programming script, using open source software. Such a research will be possible merging competences and laboratories of the 3 involved Organizations: the University of Michigan (outgoing phase, supervisor Prof. Nicola Terrenato), the University of Minho (secondment, supervisor Prof. Miguel Azenha), and the University of Bologna (return phase, supervisor Prof. Andrea Augenti). The field data will come from two projects active in the area around two ancient capitals, Rome (Gabii Project, University of Michigan) and Ravenna (Ravenna Landscape Archaeological Project, University of Bologna). As part of the MSCA-IF-2020-GF action at the Universities of Michigan and Minho, two world leading institutions in this field, I will receive the necessary high-quality training, which will allow the continuation of a successful career in the field of archaeology and the development at Bologna University of this technology, that will be transferable to any other archaeological project in EU and beyond.

Keywords: digital archaeology
Using cis-regulatory mutations to highlight polygenic adaptation in natural plant systems (AdaptoSCOPE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-09-01
End date: 2021-02-28
Duration (months): 66.0
Total project cost (EUR): 1683120.0
EU funding (EUR): 1683120.0
Participants: 1
Project status: CLOSED

The goal of this project is to demonstrate that novel aspects of the molecular basis of Darwinian adaptation can be discovered if the polygenic basis of adaptation is taken into account. This project will use the genome-wide distribution of cis-regulatory variants to discover the molecular pathways that are optimized during adaptation via accumulation of small effect mutations. Current approaches include scans for outlier genes with strong population genetics signatures of selection, or large effect QTL associating with fitness. They can only reveal a small subset of the molecular changes recruited along adaptive paths. Here, instead, the distribution of small effect mutations will be used to make inferences on the targets of polygenic adaptation across divergent populations in each of the two closely related species, A. thaliana and A. lyrata. These species are both found at diverse latitudes and show sign of local adaptation to climatic differences. Mutations affecting cis-regulation will be identified in leaves of plants exposed to various temperature regimes triggering phenotypic responses of adaptive relevance. Their distribution in clusters of functionally connected genes will be quantified. The phylogeographic differences in the distribution of the mutations will be used to disentangle neutral from adaptive clusters of functionally connected genes in each of the two species. This project will identify the molecular pathways subjected collectively to natural selection and provide a completely novel view on adaptive landscapes. It will further examine whether local adaptation occurs by convergent evolution of molecular systems in plants. This approach has the potential to find broad applications in ecology and agriculture.

Keywords: molecular adaptation,climate perturbations,plants,arabidopsis
NOVEL THERAPEUTIC FOR THE TREATMENT OF PARKINSONS DISEASE (IRL790)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-11-01
End date: 2019-02-28
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

This project’s goal is to develop a successful treatment that combats severe motor and psychotic symptoms in Parkinson’s disease (PD). PD is a debilitating neurodegenerative disorder affecting > 6 million people worldwide. It’s the neurological disorder with the highest increase in death rates, prevalence, and disability-adjusted life-years (DALYs). Levodopa, introduced more than 50 years ago, remains the most prescribed treatment for the symptomatic relief of PD, although its long-term use leads to the development of motor complications, i.e. levodopa-induced dyskinesia (PD-LIDs). IRLAB aims to address the challenge in PD treatment by clinically validating its novel compound, IRL790, aimed at reducing symptoms of PD-LIDs and Parkinson’s disease psychosis. IRLAB’s programme is based on its proprietary drug discovery platform, Integrative Screening Process (ISP), which captures a better understanding of complexities of CNS-related diseases, such as PD, and yields drug candidates with superior chance of success in the clinic. IRLAB’s therapeutic will improve intervention outcomes for PD patients in two indications. Its safety and tolerability have been validated in Phase I clinical trials and its therapeutic efficacy in PD-LIDs is being evaluated in an ongoing Phase II study. Results are expected 2018. Besides medical benefits to patients, IRL790 has also the potential to bring cost-savings to healthcare providers by effectively reducing the Parkinson’s disease burden. Generation of high quality clinical data will improve IRLAB’s opportunities for out-licensing. We plan to apply for SME grant to accelerate clinical developmental and take IRL790 through a Phase II study in PD psychosis. This way, we will out-license and market the drug sooner and for two indications (PD-LIDs and PD psychosis) simultaneously. IRLAB has an established business development contact network and have gained trust of international healthcare investors and national innovation funding bodies.

Keywords: parkinson s disease,pd lids,l dopa induced dyskinesia,parkinson s disease psychosis,small molecule
IoTree, a cutting edge low-cost, low-energy and highly sensitive solution for early detection of pests attacking trees. (IoTree)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-05-01
End date: 2018-09-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Agrint has developed IoTree, the first seismic sensor for electronic detection of the Red Palm Weevil (member of Coleoptera: Curculionidae), by detecting the burrowing activity of larvae inside the tree, in early stages. Agrint’s technology is designed to keep pest management costs to a bare minimum. The sensor’s ability to detect the weevil at a larval stage means the tree can be saved and pesticides are only applied to infested trees. Later on the technology will be applied to detect additional tree borers. Originating in southern Asia and Melanesia, where it is a serious pest of coconuts, this weevil has been advancing westwards very rapidly since the mid-1980s. Damage to palms is produced mainly by the larvae that move towards the interior of the palm making tunnels and large cavities. They can be found in any place within the palm, even in the very base of the trunk where the roots emerge. The palm tree does not show any signs of distress, until a few months later, when it begins to lose its strength. When the first symptoms of the attack appear, they are so serious that they generally result in the death of the tree. At this point, it is too late to save the tree and at the same time dozens of weevils fly off the dying tree, ready to attack new ones. Late detection constitutes a serious problem in the fight against the pest and in any attempt to guarantee pest-free status in adult trees. Overlapping generations with all life stages can be present within the same palm tree. Generally the adult weevils will not move to another palm while they can feed on it. Before IoTree, there were no effective early detection tool against the weevil as it became a worldwide catastrophe. Thus, farmers were forced to use frequent pesticide spraying. However, pesticides only offer short-term protection and must be repeated throughout the year, with a consequently costly management over time. According to the FAO, 2% of new palm tree are infected yearly.

Keywords: sensor,trees,palms,peticides,larvae