Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
FOOD SAFETY CONTROLS FOR ALL (Testforall)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: Spain
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-1-2014, 2014)
Start date: 2015-04-01
End date: 2015-09-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Food Safety controls for all ZEULAB (www.zeulab.com) is a biotechnology company specialized in the development, production and commercialization of food diagnostics tests. Our dynamic and proactive team of 25 people invests annually 25% of its activity in R&D projects. As a result of this work during almost 20 years we have developed a wide range of innovative solutions in the main areas of Food Safety and Quality (residues, pathogens, adulterations, toxins ...). ZEULAB´s test kits are commercialized worldwide through a network of distributors specialized in food diagnostics. Our company has an annual turnover around 3 million Euros and exports 70% of its products in more than 40 countries. The World Health Organization considers antibiotic resistance as one of the three greatest threats to human health for the next decades. Control of antibiotics in the primary sector and food chain is therefore one of main objectives of EU authorities. Unfortunately, there is a lack of suitable analytical systems for the primary sector (farms) and processors (slaughterhouses, dairies) to screen more than 50 authorized antibiotics. Our long experience and good market position in this field has allowed us to identify a great opportunity to develop an innovative system (e-Reader®) that transforms a laboratory assay (lab in-a-box concept) in an easy, fast and economic solution adapted to antibiotics self-controls for all food operators (farmers, dairies, slaughterhouses,…). e-Reader´s prototype complies with the EU legislation and is being validated by 3 reference laboratories in Europe. This project will place ZEULAB in the forefront of a potential market of millions of tests that will allow our company to grow at least 3-5 times (9-15 M€ and 80% of exports) in the next 5 years. This growth is based on the 600.000 EU farmers and 40.000 food plants that should implement self-controls according to EU Commission policy “from farm to fork”.

Keywords: smart device for antibiotics sefl controls for food operations
Left Atrial Appendage Electrical Isolation via Bio-photonic Optical Confirmation to Treat Persistent Atrial Fibrillation (LAA-START)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Ireland,Ireland,Israel,Ireland,Czechia
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2018)
Start date: 2019-01-01
End date: 2022-03-31
Duration (months): 39.0
Total project cost (EUR): 5012590.0
EU funding (EUR): 2999998.0
Participants: 5
Project status: CLOSED

Atrial Fibrillation (AF) is an irregular heartbeat caused by abnormal electrical activity in the heart, that can lead to blood clots with high risk of stroke and heart failure. There are 10.7 million AF patients across Europe and the US, 3.6 million are classified as having Persistent AF (PAF), they are highly symptomatic and medication resistant. Surgical electrical therapy (catheter ablation) destroys heart tissue causing the abnormal electrical pulses. For PAF patients, this works only 30% of the time. Approximately 72% of PAF patients require at least one redo procedure, amounting to €13.5 billion in wasted healthcare costs. Success rates are doubled if electrical activity in a part of the heart “the Left Atrial Appendage” (LAA), is shut down. But this increases stroke risk from blood clots as the LAA is now incapable of muscle contraction to maintain blood flow. LAA implants, “occlusion devices” fit across the opening of the LAA to filter the blood and prevent clots from entering the blood stream. However, fitting an occlusion device during the same procedure as LAA electrical isolation doubles procedure time (to 7 hours) making it non-financially viable for health services and too high risk for patients. AuriGen Medical have developed a unique, minimally invasive cardiac implant which permanently electrically and mechanically isolates the LAA in a one-shot procedure: treating both the stroke and arrhythmia risk associated with PAF with no increase in surgery time. This multi-partner FTI project will complete product development in line with the regulatory development pathway for medical devices for first in human safety and efficacy clinical studies required for CE certification and contributing to FDA clinical data requirements. The total market opportunity is $5bn/yr market opportunity across the EU and US. AuriGen will enter the market directly in the initial target European markets (Germany, France, Italy and UK) during Q3 2020.

Keywords: atrial fibrilliation,left atrial appendage electrical isolation
4-Colours/2-Junctions of III-V semiconductors on Si to use in electronics devices and solar cells (4SUNS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Spain
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-02-01
End date: 2026-09-30
Duration (months): 104.0
Total project cost (EUR): 1499719.0
EU funding (EUR): 1499719.0
Participants: 1
Project status: SIGNED

It was early predicted by M. Green and coeval colleagues that dividing the solar spectrum into narrow ranges of colours is the most efficient manner to convert solar energy into electrical power. Multijunction solar cells are the current solution to this challenge, which have reached over 30% conversion efficiencies by stacking 3 junctions together. However, the large fabrication costs and time hinders their use in everyday life. It has been shown that highly mismatched alloy (HMA) materials provide a powerful playground to achieve at least 3 different colour absorption regions that enable optimised energy conversion with just one junction. Combining HMA-based junctions with standard Silicon solar cells will rocket solar conversion efficiency at a reduced price. To turn this ambition into marketable devices, several efforts are still needed and few challenges must be overcome. 4SUNS is a revolutionary approach for the development of HMA materials on Silicon technology, which will bring highly efficient multi-colour solar cells costs below current multijunction devices. The project will develop the technology of HMA materials on Silicon via material synthesis opening a new technology for the future. The understanding and optimization of highly mismatched alloy materials-using GaAsNP alloy- will provide building blocks for the fabrication of laboratory-size 4-colours/2-junctions solar cells. Using a molecular beam epitaxy system, 4SUNS will grow 4-colours/2-junctions structure as well as it will manufacture the final devices. Structural and optoelectronic characterizations will carry out to determine the quality of the materials and the solar cells characteristic to obtain a competitive product. These new solar cells are competitive products to breakthrough on the solar energy sector solar cells and allowing Europe to take leadership on high efficiency solar cells.

Keywords: highly mismatched alloy materials,diluted nitrogen,multiband solar cells,multijunction solar cells,silicon technology,solar energy
Set theory beyond the first uncountable cardinal (BeyondA1)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Israel
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2018-10-01
End date: 2024-09-30
Duration (months): 72.0
Total project cost (EUR): 1362500.0
EU funding (EUR): 1362500.0
Participants: 1
Project status: SIGNED

We propose to establish a research group that will unveil the combinatorial nature of the second uncountable cardinal. This includes its Ramsey-theoretic, order-theoretic, graph-theoretic and topological features. Among others, we will be directly addressing fundamental problems due to Erdos, Rado, Galvin, and Shelah. While some of these problems are old and well-known, an unexpected series of breakthroughs from the last three years suggest that now is a promising point in time to carry out such a project. Indeed, through a short period, four previously unattainable problems concerning the second uncountable cardinal were successfully tackled: Aspero on a club-guessing problem of Shelah, Krueger on the club-isomorphism problem for Aronszajn trees, Neeman on the isomorphism problem for dense sets of reals, and the PI on the Souslin problem. Each of these results was obtained through the development of a completely new technical framework, and these frameworks could now pave the way for the solution of some major open questions. A goal of the highest risk in this project is the discovery of a consistent (possibly, parameterized) forcing axiom that will (preferably, simultaneously) provide structure theorems for stationary sets, linearly ordered sets, trees, graphs, and partition relations, as well as the refutation of various forms of club-guessing principles, all at the level of the second uncountable cardinal. In comparison, at the level of the first uncountable cardinal, a forcing axiom due to Foreman, Magidor and Shelah achieves exactly that. To approach our goals, the proposed project is divided into four core areas: Uncountable trees, Ramsey theory on ordinals, Club-guessing principles, and Forcing Axioms. There is a rich bilateral interaction between any pair of the four different cores, but the proposed division will allow an efficient allocation of manpower, and will increase the chances of parallel success.

Keywords: msc2010 03e05 combinatorial set theory,03e02 partition relations,03e35 consistency and independence results,03e57 forcing axioms
Tumor-lock: forbid the generation of circulating tumor cells (TUMOR-LOCK)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Switzerland
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-06-01
End date: 2026-05-31
Duration (months): 60.0
Total project cost (EUR): 1999995.0
EU funding (EUR): 1999995.0
Participants: 1
Project status: SIGNED

One woman in eight is destined to develop breast cancer. All women that lose their battle against breast cancer vividly realize that its most deadly feature is not the primary lesion, but its ability to spread to distant sites and become an incurable, metastatic disease. In this proposal, we aim to address what is arguably the most ambitious challenge in the cancer field: metastasis prevention. Metastatic spread of cancer occurs through the generation and hematogenous dissemination of circulating tumor cells (CTCs). We recently discovered that CTCs are heterogeneous, and that CTC clusters – multicellular aggregates of cancer cells and immune cells in circulation – represent the most powerful mediators of disease spread (Szczerba et al., Nature, 2019; Gkountela et al., Cell, 2019). Post-intravasation biological and clinical features of CTCs are extensively interrogated, yet, surprisingly, the mechanisms that dictate their generation from a solid tumor lesion are unknown. Only a minimal fraction of cancer cells is capable to intravasate in functional blood vessels, while the vast majority of tumor cells will always remain in situ. Understanding the fundamental biological principles that govern CTC generation is of paramount importance, as it could lead to the development of new therapeutic agents that lock tumor cells in their primary site, thereby preventing metastasis. Our preliminary data strongly suggest that CTC generation is not occurring in a stochastic fashion, but it is dictated by very precise and previously-unappreciated signals. Based on these very exciting findings, the two predominant goals of this proposal are: first, to gain insights into those fundamental cell-autonomous and non-cell-autonomous mechanisms that govern CTC intravasation in vivo. Second, to identify actionable targets and direct treatment opportunities to lock tumor cells in situ and blunt CTC generation, with the long-term ambition to prevent the metastatic spread of breast cancer.

Keywords: breast cancer,circulating tumor cells,metastasis
OPen WIreless OzoNe SEnsor NEtwoRk for smart environmental monitoring of remote areas: crossing the Alps along the 12th east meridian on the trail Munich Venice (PIONEER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy,Italy,United States
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-11-24
End date: 2024-03-30
Duration (months): 36.0
Total project cost (EUR): 251002.56
EU funding (EUR): 251002.56
Participants: 3
Project status: SIGNED

Atmospheric observatories are currently the primary infrastructure for the state-of-the-art meteorological and climate research. However, the World Meteorological Organization Global Atmosphere Watch (WMO-GAW) states in their 2018 final report that the fate of the next generation of monitoring stations will be dramatically modified by the breakthroughs of new low-cost sensors (LCSs) technologies. The rapid development and continuous improvement of low-cost technology are demonstrating notable applications and today “LCSs are beginning to play a role in areas such as model or emissions validation and spatial variability in pollution” in support the state-of-the-art instrumentations and established networks. New upcoming atmospheric applications, services and support in citizen inclusion in earth monitoring are pushing European Union (EU) in funding scientific communities, companies, governments and international bodies such as the Joint Commercial Advisory Group (JCAG) in developing and assessing low-cost technology, thus making the introduction of basic and applied research addressing quantitative, reproducible measurements, guidelines for best practice, high data quality and accuracy, compatibility of data imperative. Considering these crucial challenges, aim of the project is to establish a low-cost sensors wireless sensor network (LCS-WSN) to assess the effectiveness of low-cost technologies in the study of transboundary transport phenomena. Given its highly relevance for the Earth’s climate, ecosystems, and human health as stated by the International Global Atmospheric Chemistry Project, primary endeavor will be directed towards the study of Ozone. Main target is to develop a highly reliable LCS-WSN to be used by scientists as well as citizen engineers in remote areas and harsh environments, where the needs of reliable spatial data to model the transboundary transport phenomena and climate change effects is ever more decisive.
The Effects Of Climate Change on the Web of Life (ClimateWeb)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-07-01
End date: 2022-10-19
Duration (months): 24.0
Total project cost (EUR): 191149.44
EU funding (EUR): 191149.44
Participants: 1
Project status: CLOSED

Climate change is one of the main drivers of the current biodiversity crisis and results in shifts in species distributions. As an outcome, interactions among species are also affected. Most predictions on species’ vulnerability to climate change, however, have overlooked species interactions (the ‘web of life’), despite the interdependence of species within ecosystems, and the fact that these interactions are the cornerstones of ecosystem services. In this action, I will use a novel and integrative approach to assess the effect of climate change on the web of life (ClimateWeb). Specifically, I will assess: (Q1) Will the effects of climate change be different across interaction types (mutualisms versus antagonisms) and environments (tropical versus temperate)? (Q2) Given climate projections, does current ecological context (i.e., properties of interaction networks) or geographic properties (latitude, and longitude) best predict the fate of a species and its interactions? (Q3) How will the functional and phylogenetic diversity of communities collapse in the face of climate change? This action will use several synergistic approaches to explicitly incorporate species distributions and ecological interactions. In doing so, ClimateWeb will provide a more complete picture of the effect of climate change on the web of life and the ecosystem services those interactions provide. In addition to increasing my international mobility and career development, expected ClimateWeb results include three scientific publications, outreach activities to amplify societal awareness of climate change, and management-focused products that can be used for setting conservation priorities. This high-impact research will provide a comprehensive theoretical and empirical framework, promoting holistic thinking around the ecological problems that climate change poses, and helping to ensure the long-term functioning of the web of life, as well as the ecological services it provides.

Keywords: species interactions,ecossystem services,anthropocene,species distributions
Development of a methodology (test, measurement, analysis) to characterize the BEhaviour of composite structures under DYNamic loading (BEDYN)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Spain,Spain
Call: Development of a methodology (test, measurement, analysis) to characterize the behaviour of composite structures under dynamic loading (H2020-CS2-CFP10-2019-01, 2019)
Start date: 2020-07-01
End date: 2023-06-30
Duration (months): 36.0
Total project cost (EUR): 499537.5
EU funding (EUR): 499537.5
Participants: 3
Project status: SIGNED

The goal of the project is to develop a methodology (including innovative tests, measurements, and analysis methods) to properly characterize the dynamic behaviour up to rupture of composite structures submitted to a dynamic loading. Simulations will be used to prepare and analyse tests and a simulation methodology will be developed to demonstrate prediction capabilities.

Keywords: composite materials,dynamic test,dynamic modeling,industrial methodology,fracture
Metrics for Sustainability Assessment in European Process Industries (MEASURE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Sustainable, resource-efficient and low-carbon technologies in energy-intensive process industries
Action type: Coordination and support actions
Countries involved: Germany,Germany,Germany,Germany,Belgium,Belgium,United Kingdom,United Kingdom
Call: Methodologies, tools and indicators for cross-sectorial sustainability assessment of energy and resource efficient solutions in the process industry (H2020-SPIRE-2014, 2014)
Start date: 2015-01-01
End date: 2016-03-31
Duration (months): 15.0
Total project cost (EUR): 499875.0
EU funding (EUR): 499875.0
Participants: 9
Project status: CLOSED

The aim of the CSA MEASURE is to provide support and guidance, how to reach the H2020 SPIRE Public Private Partnership goals on reduction in fossil energy intensity, non-renewable, primary raw material intensity and greenhouse gas emissions in the most effective way. MEASURE will deliver a roadmap how to evaluate processes in a standardised, comparative way. Benefiting from the strong support of our cross-sectorial Advisory Board, the impact of the MEASURE roadmap shall outreach the H2020 SPIRE programme towards harmonised standards for sustainability assessment in the entire European process industry. MEASURE will bring together leading European process industries in chemistry, consumer goods, steel, automotive, non-ferrous metals, water and waste with well-known research centres, and academic experts with profound complementing expertise on sustainability assessment with regulators and standardisation bodies. Lead users will be innovative companies of all sectors of European process industry and academic partners supporting their maintenance of leadership in enabling technologies and advanced materials & processes as well as public authorities and standardisation bodies. The phases of work will include a detailed, cross-sectorial stakeholder analysis on the use of existing sustainability metrics and decision support tools for different goals, stages and data availabilities; an in-depth dialogue between the MEASURE core team and the Advisory Board during two organised workshops and as final outcome, a harmonised roadmap towards universally accepted and standardised tools for environmental, economic and social assessment in process industries over the whole value chain. Implementation will take place by open access publication of the roadmap as well as its widespread promotion in the existing network of the MEASURE partners including UNEP/SETAC, ISO, DIN, WBCSD, FAO, CEFIC, SusChem, PlasticsEurope, FEFANA, World Steel, RSC, GDCh, IChemE, DECHEMA, JRC ISPRA.

Keywords: sustainability,energy efficinecy,resource efficiency,process industry,assessment rules