Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Carotid-artery-on-a-chip device to model thromboembolisms induced by vascular lesions and perform drug screenings (CAR-OAC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-02-17
End date: 2022-02-16
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

This project will be focused on designing a microfluidic device to visualize haemodynamics within a carotid-artery mimetic device. The system will be designed to evaluate associations especially between fibrinogen, erythrocytes, and platelets when subjected to shear and coagulation-inducing factors. The design will include biologically and mechanically variable properties as may occur in transient ischaemic attacks (TIA). The intended system is to have similar composition and dimensions as the extra-cranial (common to internal) carotid arteries. Physiologically relevant dimensions will be implemented where the common artery will have a lumen diameter of 6.1 mm with variable thickness (0.6 to 0.9 mm), whereas the internal artery will be 4.7 mm in diameter with thickness of 0.7mm. The system will be equipped with pressure and stretch-inducing mechanics which can be modulated to trigger rheological and biological responses. Specifically, stretching will cause exposure of tissue factor and lipids, capable of triggering inflammatory coagulation. The proximal formation of biological or physical occlusions will be assessed using this device. Also, the design will enable visualization of intra-vascular activity as may be illustrated in live high-resolution confocal microscopy. Flow properties of liquids with varied rheological properties similar to blood will be tested. Clinicians and researchers studying the pathology of strokes and TIAs or conducting studies on intravascular thrombosis will be able to engage this device in experiments while pharmaceutical developers will be able to engage the device in testing actions of therapeutic agents. Stroke remains the second leading cause of death globally and through the development of this device, both developers and potential users of the device will be able to explore effective and applicable solutions. Elvesys will avail the researcher an enriching environment to master IP, marketing concepts, patenting and public engagement.

Keywords: vasculature on a chip,microfluidics,elastic modulus,biophysics,cardiovascular,membrane dynamics
Looking for the Impersonal Core -- Impersonal Pronouns across Germanic languages (IPG_CORE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 202158.72
EU funding (EUR): 202158.72
Participants: 1
Project status: CLOSED

IPG_CORE examines the grammatical properties of German, Norwegian, and Swedish impersonal pronouns outside of and inside attitude contexts (i.e., sentential arguments of attitude verbs, like "believe"). The aim is to provide new linguistic data and theoretical results that allow us to settle the question whether the behaviour of impersonal pronouns can be traced back to a single impersonal core meaning. I will conduct this investigation using empirical methodology developed in corpus linguistics (i.e., corpus studies) and linguistic typology (i.e., questionnaire studies). In addition, I will incorporate two lines of theoretical research into the current discussion that have so far been pursued independently of the research on impersonal pronouns: the semantic behavior of (pro)nominal expressions in attitude contexts and results on pronominal typology. The ideal environment to tackle both the empirical and theoretical aspects of IPG_CORE is the Department of Linguistics and Scandinavian Studies at the University of Oslo (UiO). Close collaborations with my supervisor Prof. Patel-Grosz and the colleagues at the department, scientific and practical support, high-level training opportunities, one-of-a-kind resources (e.g., the Oslo Multilingual Corpus), and an overall inspiring working atmosphere distinguish the UiO as the ideal place to bring IPG_CORE to a fruitful conclusion.

Keywords: norwegian,swedish and german impersonal pronouns,cross linguistic comparison,morphosyntactic and semantic analyses,corpus studies and linguistic questionnaires,nominal expressions in attitude contexts
Collaborative Agri-food Chains: Driving Innovation in Territorial Food Systems and Improving Outcomes for Producers and Consumers (COACH)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Coordination and support actions
Countries involved: Austria,Germany,Germany,Spain,Spain,Italy,Germany,Belgium,Romania,Hungary,Georgia,France,France,France,Czechia,United Kingdom,Denmark,United Kingdom
Call: Connecting consumers and producers in innovative agri-food supply chains (H2020-RUR-2020-1, 2020)
Start date: 2020-11-01
End date: 2023-10-31
Duration (months): 36.0
Total project cost (EUR): 3021762.5
EU funding (EUR): 3021762.5
Participants: 20
Project status: SIGNED

Farmers and small operators are often in a weak position in the value chain. They lack bargaining power, face barriers to accessing markets, and struggle to achieve a fair income. At the same time, due to growing public awareness of the environmental crisis, and the rise of diet-related ill-health, many consumers want to conveniently access high quality, healthy and sustainable foods. In response, many innovative consumer-driven opportunities for farmers to access markets are now available. The aim of this project is to facilitate collaboration between farmers, consumers, local governments and other actors to scale up short agri-food chains which rebalance farmers’ position, create win-wins for producers and consumers and drive innovation in territorial food systems. It does this in five key ways. First, it develops a ‘living library’ of 32 emblematic good practice examples from 12 countries which demonstrate how farmers can access consumer-driven opportunities to improve their incomes and rebalance their position in food chains. Second, it delivers a knowledge-based suite of activities to support farmers and small operators to access information on consumer demand and improve their capacity to connect with consumers. Third, it provides new insights and guidance on the costs and margins for each link in the supply chain, demonstrating opportunities for improved incomes for farmers and small operators and reduced costs for intermediaries. Fourth, it designs a ‘farm-to-fork procurement toolkit’ for public authorities in order to improve sharing of experience and help them design appropriate tenders for healthy and fresh food supplied by small-scale producers and also to support farmers to know how to access these opportunities. Fifth, it maximises the impact of all the project’s activities through effective communication and dissemination including policy engagement in order to create a more enabling environment for collaborative agri-food chains.

Keywords: collaborative agri food chains,territorial food systems
Pediatric Avoidant and Restrictive Eating: A biopsychosocial investigation (PAREAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-04-01
End date: 2023-10-29
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: SIGNED

Avoidant Restrictive Food Intake Disorder (ARFID) is a newly defined psychological disorder that is estimated to affect ~5% of children. Children with ARFID eat a limited quantity or range of foods due to sensory sensitivity to the food (i.e., taste, smell, texture, temperature, appearance), low interest/appetite, fear of adverse consequences of eating (e.g., choking, vomiting, pain), or a combination of these reasons. ARFID causes children to have significant nutritional deficiencies, growth impairment and/or significant psychosocial problems. However, little is known about what causes ARFID, particularly in early childhood when symptoms typically begin. A recent attempt to inform the pathophysiology of ARFID has been made through the introduction of the Three-Dimensional Neurobiological Model of ARFID, but this model has yet to be evaluated in early childhood. Given the powerful effect of parent feeding behavior on early childhood eating, it is essential to understand how parent feeding behavior interacts with a child’s biological vulnerabilities for ARFID to develop effective behavioral interventions for ARFID in early childhood. I will extend my research on child anxiety, parenting behavior and psychophysiological assessment, while obtaining essential training in the etiology and biology of feeding and eating disorders and emotional processing of food stimuli to conduct the first evaluation of the interaction of biological risks and parenting behavior on ARFID symptoms in young children. In a sample of 60 children ages 4-7 years (30 with avoidant/restrictive eating and 30 typically developing controls), I will 1) identify biological vulnerabilities for the sensory sensitivity and fear dimensions of avoidant/restrictive eating and 2) test the interaction of parent factors and biological vulnerabilities on the severity of symptoms in the sensory sensitivity and fear of aversive consequences dimensions of avoidant/restrictive eating.

Keywords: avoidant,restrictive eating,etiology,psychopathology,psychophysiology,early childhood,parent behavior,anxiety,sensory sensitivity
Evolutionary origin and impact of germline-restricted chromosomes (GermlineChrom)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Germany,United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-10-01
End date: 2026-09-30
Duration (months): 60.0
Total project cost (EUR): 1994180.0
EU funding (EUR): 1885403.39
Participants: 2
Project status: SIGNED

Many multicellular organisms have a division between germline and soma. It has been long-standing dogma that all these cells have the same genome as they develop from a single cell. However, programmed DNA elimination can remove DNA during germline–soma differentiation and thereby lead to dramatic differences in genome organization between tissues. The evolution and function of programmed DNA elimination remains mysterious due to technological limitations and lack of an evolutionary framework. However, a role of this phenomenon in minimizing germline–soma genetic conflict has been suggested. This conflict arises when developmental gene expression is beneficial for the germline but deleterious for the soma. The aim of this proposal is to test whether programmed DNA elimination allows germline-specific expression of developmental genes to minimize germline–soma conflict. Using the germline-restricted chromosome (GRC) of the zebra finch as a unique study system, I have recently pioneered high-throughput genomics to overcome previous limitations. Combining my novel approach with transcriptomics, proteomics, cytogenetics, and developmental and functional genomics will provide unprecedented insights into the evolution and function of germline–soma genome differences. First, I will establish the so far first GRC study system by generating a zebra finch GRC reference assembly. Second, I will test how the GRC is inherited and maintained in zebra finch populations. Third, I will elucidate the long-term evolutionary history of GRCs across songbirds to reveal genes that are most conserved and thus candidates for GRC function. Fourth, I will trace GRC expression and elimination across zebra finch development, and functionally validate candidate genes. Altogether, I will establish an evolutionary framework which will significantly advance our understanding of programmed DNA elimination during germline–soma differentiation, a phenomenon likely widespread across the Tree of Life.

Keywords: programmed dna elimination,germline soma genome differences,genetic conflict,molecular cytogenetics,single molecule genomics,comparative genomics,population genomics
Silicon Photonics Transceiver and Routing technologies for High-End Multi-Socket Server Blades with Tb/s Throughput interconnect interfaces (ICT-STREAMS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Partnership: Photonics (cPPP)
Countries involved: Italy,Germany,Italy,Switzerland,Belgium,Switzerland,Greece,France
Call: Photonics KET (H2020-ICT-2015, 2015)
Start date: 2016-02-01
End date: 2019-07-31
Duration (months): 42.0
Total project cost (EUR): 4086809.5
EU funding (EUR): 2917134.5
Participants: 10
Project status: CLOSED

The overall objective of STREAMS is to develop the necessary Silicon Photonics Transceiver and Routing technologies towards a new, power efficient, WDM-based, Tb/s, optical on-board interconnection paradigm that enables multiple high bandwidth, point-to-point direct links on the board level, as a step forward to the realization of exa-scale computing systems. Through the migration of successful WDM networking practices to the mid-plane computercom level, STREAMS will develop a distributed routing system based on a passive Si-Pho AWGR routing element to provide simultaneous any-to-any communication between 16 end-points, such as high-end processor sockets. STREAMS will also develop a novel DWDM, software controlled, Si-Pho embedded optical modules to interface each socket CPU with the WDM routing platform, in order to guarantee successful wavelength routing and interconnection of CPUs by correctly correlating the data to the designated transmission wavelengths. STREAMS optical engine will exhibit 1.6 Tb/s throughput with 50 Gb/s line rate over 32 wavelength channels, enabling a massive any-to-any, buffer-less, collision-less and extremely low latency routing platform with 25.6Tb/s aggregate throughput. The proposed STREAMS distributed routing system allows maximum granularity of the network resources and their optimal allocation with energy saving criteria. Finally, STREAMS will develop a single-mode polymer based electro optical-PCB to host the WDM-based optical engine and router modules to form a complete power efficient, cost-effective high-speed Optical Path Interconnect for multiple end-point mid-board systems that will outperform current state-of-the-art multi-socket server blades technology by an order of magnitude in aggregated throughput and link power efficiency.

Keywords: embedded optic module,optical engine,optical transceiver,silicon modulator,sige photodetector,on board optical interconnects,electro optical pcb,polymer waveguide pcb,wdm routing,wdm lasers
Intelligent human diagnostic and therapy platform (Cardiacom IMPLANT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Hungary
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2014-12-01
End date: 2015-02-28
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In OECD countries the most frequent cause of mortality is cardiovascular diseases. Addressing this problem needs a holistic approach, where ICT-based monitoring is in the focus. The disruptive innovation programme sets the target of performing complex mobile invasive monitoring of cardiovascular and associated diseases, of forecasting the state of the patients, supporting the therapy treatments and assessing the effectiveness of drugs on mobile information-technology-base. The devices are miniature holter monitors built into the human body, which with their diagnostic algorithm will regularly or continuously assess and check the physiological condition of the users. Innovation content: 7/24 monitoring, continous data processing, intelligent automated evaluation systems, lifelong mobile crisis management, optimized drug taking protocol, implants with long life. Main ecomic benefits: higher health and life safety, higher economic efficiency as a result of the improvement in people health condition, less patient-doctor appointment, reduced cost of cardiovascular treatment, reduced number of operations. Main target group: patients who have been/will be operated on any cardiovascular disease and people who have high risk factor. The business model is built on the sale of appliances and on the sale of the related subscription-based info-communication service packages. According to the initial financial plan we count with a turnover of 100.000 pieces and an outstanding profit and return by the end of the fifth year after the market launch. We plan the diffusion of the system in three steps with expanding geographical coverage. Before entering the markets we establish dealerships in the regions and develop a regional distributor and technical support system as well. As desired achievements of the phase 1 five main parts of the Feasibility Study will be elaborated: Market Analysis Business Plan, Marketing Plan, Legal and Organisational Plan and Technological Plan.

Keywords: human diagnostic,therapy platform,medical device,invasive monitoring,cardiovascular diseases,implant technology,information system
Training on energy audits as an Energy Efficiency DRIVER for the automotive sector (E2DRIVER)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Germany,Spain,Italy,Italy,Germany,Germany,Germany,Spain,Belgium,Greece,France,France
Call: Capacity building programmes to support implementation of energy audits (H2020-LC-SC3-EE-2018, 2018)
Start date: 2019-06-01
End date: 2022-05-31
Duration (months): 36.0
Total project cost (EUR): 1999997.9
EU funding (EUR): 1999997.5
Participants: 13
Project status: CLOSED

E2DRIVER will develop a collaborative-cooperative training platform boosting the automotive supply industry collective intelligence on energy efficiency. The platform will provide access to training material, online lessons, guidelines, energy and financial tools, virtual reality modules and a community of key actors in the sector for SMEs to undergo energy audits and implement their recommendations. To this end, E2DRIVER training methodology will enable the development of specific training plan itineraries based on the company’s needs and trainees’ role in the company, which will increase the effectiveness of the training sessions and the awareness on energy issues among the staff. The development of E2DRIVER platform will not be a static action resulting from the project execution, but will enable a continuous update of the training material, best practices, benchmarking analysis and guidelines due to the implementation of an ontological flip teaching method, which enables trainees to generate their own knowledge and training materials to be shared through E2DRIVER cooperative networks. E2DRIVER platform will be tested and validated in 40 companies from the automotive supply industry in four countries that represent over 50% of the EU employees in this sector: Spain, France, Italy and Germany. Moreover, a total of 60 trainers will be certified in E2DRIVER training methodology, which will ease the replication of the project results and the business consolidation of E2DRIVER platform. E2DRIVER gender-balanced consortium includes three well-known research institutions with expertise in energy efficiency, social science and decision-making processes. In addition, a partner in charge of training at national level and an association as multiplier organization has been involved in every pilot country. Finally, this competitive consortium is complemented by two research oriented SMEs focussed on exploitation and dissemination issues.

Keywords: energy audits,capacity building programmes,virtual reality,flip teaching,adaptive learning environment,blended learning,behaviour change,automotive supply industry,cooperative networks
Wireless Powered Communication Networks: Architectures, Protocols and Optimized Resource Allocation (WPCN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Wireless powered communication network (WPCN) is a promising networking paradigm for future wireless communication systems, where the batteries of wireless devices (WDs) are remotely replenished by means of microwave wireless power transfer (WPT) technology. Compared to the conventional battery-powered communication networks, WPCN is in general more convenient by eliminating the hassle of connecting cables, more cost-effective by enabling on-demand energy supplies and maintenance-free operations, more environmental-friendly by avoiding tons of battery disposal yearly, and is sometimes essential for scenarios where manual battery replacement/recharging is too dangerous (e.g., in hazardous environment) or even impossible (e.g., for biomedical implants). However, the practical deployment of WPCN is hampered by several critical issues, such as the low end-to-end WPT efficiency over a long distance, the inter-play between power and information transmissions within the same network, and the challenges of scalability in large networks. This project aims to resolve the above issues by paving the way for the practical deployment of WPCN. Towards this end, a comprehensive study on WPCN will be pursued, ranging from the networking architecture and protocol designs to optimized resource allocation. A number of innovative techniques will be proposed and thoroughly investigated in this project, including the new heterogeneous networking architecture for WPCN, the harvest-and-transmit protocol facilitated by the concept of energy-and-information full-duplexing, and the distributed energy beamforming technique with the idea of WD-initiated WPT. The results obtained in this project will find a wide range of applications in the fifth generation (5G) wireless communication system, which involves numerous low-power WDs, including those in wireless sensor networks (WSNs), internet of things (IoT), and massive machine-type communications.

Keywords: wireless communications,wireless power transfer,wireless powered communications,internet of things,resource allocation