Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Apply ligninases to resolve end-of-life issues of thermoset composite plastics (BIZENTE)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Public-private partnerships
Destination: Bio-based Industries
Action type: Research and Innovation actions
Partnership: BBI (Art-187)
Countries involved: Spain,Spain,Spain,Spain,Spain,Spain,Italy,France,Netherlands,Denmark
Call: Apply microorganisms and/or enzymes to resolve end-of-life issues of plastics (H2020-BBI-JTI-2019, 2019)
Start date: 2020-05-01
End date: 2024-04-30
Duration (months): 48.0
Total project cost (EUR): 3185071.25
EU funding (EUR): 2509342.3
Participants: 13
Project status: SIGNED

BIZENTE project presents an innovative solution to resolve the end-of-life of thermoset composites based on the development of a new technology focused on a controlled enzymatic biodegradation. BIZENTE technology will contribute to decrease the amount of non-biodegradable polymers currently discharged to the environment or sent to landfill and incineration in at least a 40%. The solution will imply opening a biocatalytic process to new type of feedstock (3 thermoset resins and composites) not previously approached in the plastics value chain. BIZENTE will determine directed enzyme evolution strategies to improve ligninolytic oxidoreductases which have been selected as the most suited biocatalysts to degrade the three types of thermoset composites addressed in the project (epoxy, polyester and vinylester). Once this new technology has been optimised and scaled-up to a pilot environment, the biodegradation products will be valorised into new building blocks for the chemical industry. BIZENTE project will directly contribute to achieve SIRA’s in KPI1, KPI2 and KPI8. BIZENTE consortium involves 10 partners: 3 RTD (Aitiip, UCA and TuDelft), 5 SME (EvoEnzyme, BSP, SP, PLATA and ECRT), and 2 Large Companies (ACCIONA and AED), accounting to 1 BIC full member (BIOPHERE) and 3 associated (AITIIP, UCA, TUDELFT). It involves partners from 5 EU countries (ES, NL, FR, IT, DK). The 48-months proposed will comprise a total estimated budget of 3,182,571 €; being the 21,2% covered by consortium own contribution (in-kinds) and adding 223,764.5 € in additional activities during the project implementation and 2,350,000 € envisaged to upgrade TRL after the end of the project. Benefits will be significant in terms of EU growth (13,1%) and increasing jobs (16 direct, 1000 indirect) by promoting at least 2 new sector interconnections in the new created “enzymatic circular VC for composite materials”.

Keywords: ligninolytic oxidoreductases ligninases,directed evolution methodologies,thermoset composites,epoxy resins,polyester resins,vynilester resins
Biological Impact of Benzoxazinoid Metabolization by a Specialist Root Herbivore (BISEM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-06-01
End date: 2023-05-31
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: SIGNED

Some herbivores can sequester and use plant secondary metabolites for their own defense. Despite many examples of sequestration, the impact of these compounds on herbivore performance and natural enemy resistance in still not well understood, especially for root herbivores. The objective of this project is to investigate the biological relevance of benzoxazinoid N-glycosylation by the western corn rootworm Diabrotica virgifera virgifera, one of the main pests of maize that sequesters benzoxazinoids from maize roots. To reach this aim, the project will combine mass spectrometry imaging with environmental RNAi and ecological assays to understand how the formation of N-glycosylated benzoxazinoids affects herbivore performance and resistance to entomopathogenic nematodes. This will be the first study to investigate the relevance of secondary metabolite sequestration in a root pest through molecular manipulation. This project will shed light on the importance of plant defense sequestration for root-feeding insects, for plant-insect interactions and for crop protection.

Keywords: plant herbivore interactions,western corn rootworm,maize,sequestration of plant secondary metabolites
Dynamical effects on neutral excitations (DENE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-01
End date: 2017-05-31
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

The aim of the present project is the development of a theoretical tool for the description of neutral excitations that are directly probed in absorption, electron energy loss and inelastic X-Ray scattering experiments. It is focused on the description of dynamical effects beyond the quasi particle picture that are not taken into account in the present theories. The final goal will be the correct description of the spectrum in systems where dynamical effects are not negligible as metals and strongly correlated insulators, the description of multiple excitations that are not included in a quasi particle picture and the understanding of the role played by electronic correlations on the lifetime of neutral excitations. Particular attention will be devoted to the problem of the multiple excitations in strongly correlated transition metal oxides.

Keywords: mbpt,theoretical spectroscopy,dielectric response,qb initio,strongly correlated materials
Developing Protocols to standardize the development and documentation of energy efficiency projects in the built environment and accelerate their financing. (ICPEU)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Market uptake of energy innovation
Action type: Coordination and support actions
Countries involved: Germany,Austria,Belgium,Bulgaria,Netherlands,United Kingdom,United Kingdom,Luxembourg,United Kingdom,Portugal,United Kingdom
Call: Improving the financeability and attractiveness of sustainable energy investments (H2020-EE-2014-3-MarketUptake, 2014)
Start date: 2015-02-01
End date: 2018-01-31
Duration (months): 36.0
Total project cost (EUR): 1912187.5
EU funding (EUR): 1912187.5
Participants: 11
Project status: CLOSED

The importance of increasing investor confidence in energy efficiency as an asset class was stressed in a recent EU chartered Energy Efficiency Financial Institutions Group report which also highlighted the US based Investor Confidence Project as “a relevant model” and recommended “an EU Investor Confidence Project”. This project will deliver that Investor Confidence Project (ICP) to the EU. Several studies document the potential energy savings for efficiency investments as well as the scale of the investment needed. BPIE estimated EUR937bn investment would be necessary in their Deep Scenario to achieve 78% energy savings and 90% CO2 savings. Despite evidence of the potential attractiveness of investments, the flow of finance into energy efficiency remains much lower than required. Analysis reveals several barriers that hold private capital back but especially a lack of standardised processes and documentation, analogous to those used in the oil & gas and renewables industries. All financial markets are enabled by buyers and sellers agreeing standards. Scaling up investment in efficiency will require standardisation and greatly increased capacity in the financing market – ICP Europe addresses these issues. The project will work with key stakeholders to develop open source Protocols and apply them to real projects. The project has measurable KPIs but the real aim is to get commitment from investors that they will specify the use of the Protocols by project developers seeking finance – making them standards. The advantages of standardization, the adoption of the ICP in the US, and the high level of interest from EU investors that this pan-European multi-disciplinary consortium has already demonstrated lead us to believe that this is realisable objective within the 36 month project. A few key early financial adopters in each market will lead to wider adoption. We have already identified and engaged with a significant number of potential early adopters.

Keywords: standardisation,transaction costs,investment,financing
Simultaneous transformation of ambient heat and undesired vibrations into electricity via nanotriboelectrification during non-wetting liquid intrusion-extrusion into-from nanopores (Electro-Intrusion)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Emerging themes and communities
Action type: Research and Innovation actions
Countries involved: Ukraine,Italy,Spain,Poland,Belgium,United Kingdom
Call: FET Proactive: emerging paradigms and communities (H2020-FETPROACT-2020-2, 2020)
Start date: 2021-01-01
End date: 2025-12-31
Duration (months): 60.0
Total project cost (EUR): 3651381.25
EU funding (EUR): 3651381.25
Participants: 6
Project status: SIGNED

Greenhouse gas emissions, pollution and rational energy use are civilization-scale challenges which need to be resolved urgently, in particular by the conversion of abundant waste heat and undesired vibrations into useful electricity. However, the low efficiency of existing conversion methods does not provide an attractive solution. Here we propose a new and highly efficient method and apparatuses for the simultaneous transformation of mechanical and thermal energies into electricity by using zero-emission nanotriboelectrification during non-wetting liquid intrusion-extrusion into-from nanoporous solids. To tackle these phenomena, we bring together a consortium of multidisciplinary teams specializing in physics, chemistry, material science and engineering to address the project by the state-of-the-art methods of MD simulations, high-pressure calorimetry and dielectric spectroscopy, materials synthesis and characterization, and prototype development. The FET-PROACTIVE call is a key solution to bring this early stage multidisciplinary concept to higher TRLs, fill in the large knowledge gaps in the solid-liquid contact electrification and heat generation during intrusion-extrusion as well as enable its full impact on EU innovation leadership, competitive market and energy sector security. The proposed method can be used for energy scavenging within a wide range of technologies, where vibrations and heat are available in excess (train, aviation, domestic devices, drilling, etc.). In particular, using European Environment Agency data we estimate that the use of the proposed approach only within the automobile sector can reduce the overall EU electricity consumption by 1-4% in 2050. With this regard, the final stage of the project implies regenerative shock-absorber development and field-testing for a drastic maximization of the maximum range of hybrid / electric vehicles.

Keywords: triboelectrification,contact electrification,energy conversion,solid liquid interface,wetting,porous materials,regenerative shock absorber,heat pump,energy scavenging,energy dissipation
Cross-evolutionary dissection of the functional plasticity of the ribosomal epitranscriptome (EpiRibo)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Israel
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2022-05-01
End date: 2027-04-30
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

A remarkable diversity of post-transcriptional modifications adorn the ribosomal RNA (rRNA) throughout all domains of life. While initially conceptualized as a constitutive component of the ribosome, recent evidence demonstrates that some modifications are only present on a fraction of cellular ribosomes, and our lab recently revealed unprecedented environmentally-mediated dynamics of an rRNA modification. This suggests that some rRNA modification may serve as a tunable layer for regulation of ribosome properties, facilitating adaptation to a new environment, stress or pathological state. Here we aim to systematically explore the extent to which rRNA modifications are tunable across evolution and highly diverse growth conditions, and to understand the consequences thereof. We seek to understand which rRNA modifications are subject to regulation, to uncover the contexts in which such regulation occurs, and to unravel the underlying mechanisms. Dissecting these questions requires an approach allowing systematic measurement of diverse rRNA modifications. We propose to establish a streamlined workflow, allowing multiplexed, precise, robust and cost-efficient systematic profiling of 19 distinct rRNA modifications in dozens of samples in a single experiment (Aim 1). In Aim 2, we will systematically measure rRNA modifications across the three domains of life, focusing on species that can thrive across two widely different physical/chemical gradients, where the potential for tunable rRNA modifications is particularly high. In Aim 3, we will combine gain- and loss-of-function approaches to systematically explore the functions RNA modifications can bestow on ribosomes. Collectively, EpiRibo addresses a fundamental open question regarding the extent of plasticity and regulatory potential present within the ribosome itself and encoded via its epitranscriptome, setting the stage for investigations in other RNA species, and in more complex and disease-related contexts.

Keywords: epitranscriptome,rna modifications,post transcriptional regulation,rrna modifications
Industrialization of software and libraries for crack propagation in material and structures using the Thick Level Set method (MATCRACK)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2017-09-01
End date: 2019-02-28
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The understanding and the reliable prediction of material degradation, crack initiation and propagation is of vital importance in engineering. It allows the evaluation of product lifecycle and the criticality of exceptional loads. Also, it enables maintenance optimization in a wide range of industries (automotive, aircraft, nuclear…). Thanks to the ERC “XLS” grant, a new approach coined TLS (“Thick Level Set”) was developed to simulate crack propagation from sane material to critical rupture. The main advantage of this approach is that it takes into account both crack initiation and crack propagation without mesh size or mesh orientation dependency. This combination is not currently available in the industry. The TLS software sources (coined TTK for TLS Tool Kit) has been produced mostly during the ERC project. They were recently registered in the software protection agency. The POC goal is to transform the TTK software to industry usable software and to reach a win-win agreement with a well-established service company who will perform paid studies.

Keywords: fracture,damage,crack,simulation,software
Deep Decarbonisation: The Democratic Challenge of Navigating Governance Traps (DeepDCarb)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Germany,United Kingdom
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2021-03-01
End date: 2026-02-28
Duration (months): 60.0
Total project cost (EUR): 2395525.0
EU funding (EUR): 1864275.0
Participants: 2
Project status: SIGNED

The standard advice to politicians confronting long-term challenges such as decarbonisation is to adopt time-consistent commitment devices such as binding policies. Yet politicians appear unable to do this, greatly imperilling the achievement of the 1.5 and 2oC limits in the landmark Paris Agreement. The state-of-the art struggles to explain the causes, and hence the solutions, to this impasse. Political scientists argue that politicians fear retribution at the next election; psychologists claim that citizens understand what is at stake, but expect politicians to lead. The untested assumption is that both are locked into a ‘governance trap’ which greatly reduces the political feasibility of rapid change. DeepDCarb seeks to significantly advance the academic state-of-the-art by directly interrogating the relationship between politicians, citizens/voters and other actors in a uniquely detailed and comparative manner, drawing on an unconventional combination of methods and unrivalled new data sets. It will establish a new subfield of interdisciplinary research that: • Explores the commitment devices that all states in the world have adopted, via a nested array of 13 new datasets and time-sensitive statistical techniques; • Opens up the ‘black box’ of societal commitment formation in a sample of large emitters (including the EU-28) to explore the relationship between politicians and citizens (1990-2020); • Investigates the scope for unlocking traps by bringing actors together in deliberative fora such as citizens’ assemblies, thus confronting the uncomfortable question of how far societal commitment is more effectively engendered by depoliticising or politicising contentious issues. The findings, to be widely disseminated through a programme of publication and public engagement, will contribute significantly to understanding the scope for unlocking the profound impasse in society’s struggle to deliver deep decarbonisation.

Keywords: climate change,decarbonisation,policy,politicians,publics
Justinmind XR: The First Code-Free Rapid Prototyping Platform for eXtended Reality (VR/AR/MR) and Spatial Computing (JUSTINMIND-XR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-09-01
End date: 2021-10-31
Duration (months): 26.0
Total project cost (EUR): 1581096.25
EU funding (EUR): 1106767.38
Participants: 1
Project status: CLOSED

We live and think in a 3D world, not on a flat screen, and Justinmind XR wants to become the first Rapid Prototyping Platform (RPP) for designing Spatial Computing Software Applications, overcoming outdated conventions of point and click interfaces, delivering a more natural and intuitive way to design and create applications for immersive 3D environments, in the space of eXtended Reality (XR), XR including Virtual, Augmented and Mixed Reality (VR, AR, MR). Justinmind XR will be the first SaaS Cloud Platform to design XR applications without writing a single line of code. This cross-cutting approach will therefore speed up many fields such as EdTech applications for the classroom, eHealth and Assistive technologies, XR applications for treatment of mental health disorders, surgery AR/VR applications, Human-Robot Interaction Interfaces and industry 4.0 manufacturing technologies, Cyber-Physical Systems, Real-Time collaboration platforms, Aerospace simulators, Data visualization, e-Government and many more. Developing XR applications is still very difficult, with long project set ups and high failure rates. We overcome the problem thanks to our Zero-Code Technology (ZCT), 100% ‘Code Free’, powered by BigData Analytics, Deep Learning and a full Drag&Drop and ‘zero code’ IDE, enabling participation and collaboration to not only Developers but also professionals without any coding skills: like User Experience (UX) Designers or Business Analysts... that can be now involved in any XR project from the beginning. +2 million users worldwide already use www.justinmind.com to design applications for Web, Mobile, Desktop and IoT. We are ready to extend our knowledge to the new XR/3D/Spatial Computing paradigm and disrupt the $94.4B VR/AR industry, achieving an estimated $30M - $40M annual turnover in 4-5 years and generating +80 VR/AR High-Skilled hires in the process. Justinmind XR project has been awarded in previous submissions with two Seals of Excellence.

Keywords: user interface,user experience,extended reality,augmented reality,virtual,reality,mixed reality,prototyping,wireframing,simulation,user testing,usability,testing