Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
EXTREME Dynamic Loading - Pushing the Boundaries of Aerospace Composite Material Structures (EXTREME)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Israel,Italy,Germany,Belgium,Greece,Belgium,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Competitiveness of European Aviation through cost efficiency and innovation (H2020-MG-2014_TwoStages, 2014)
Start date: 2015-09-01
End date: 2019-08-31
Duration (months): 48.0
Total project cost (EUR): 5277597.5
EU funding (EUR): 5277597.5
Participants: 14
Project status: CLOSED

The European industry is currently a world leader in aviation and to maintain its leading position and competitiveness in the dynamic global market, Europe’s industry must develop quickly and efficiently high quality products by meeting time-critical market demands and customers’ needs. Industrial competition is becoming fiercer not only from established regions, such as the USA, but from new emerging challengers, such as Brazil, Canada, etc. Technological leadership and innovation is becoming the major competitive differentiator, most notably in terms of costs, and environmental performance. The market demands shorter cycles of new technology integration and, on the other hand, competitors enter the market with aggressive prices. It is forecasted that in 2050, innovative products and services demanded by the market will be based on state of the art design, manufacturing and certification processes with a significant reduction of the environmental impact. Recent studies have shown that the development and deployment of new structural technologies will have the greatest impact in the reduction of weight and operational costs compared to other technologies. Against this background, composite materials technology is of fundamental importance to current and future aircraft structures where high specific properties and integration of multiple functionalities are essential to improve weight, fuel efficiency, reduce CO2 emissions, and certification costs. The vulnerability of composite structures to localised, dynamic, sudden, and unexpected loads, may result in unpredictable complex localized damage and a loss of post-impact residual strength. The aim of the EXTREME project is to develop novel material characterisation methods and in-situ measurement techniques, material models and simulation methods for the design and manufacture aerospace composite structures under EXTREME dynamic loadings leading to a significant reduction of weight, design and certification cost.

Keywords: extreme dynamic loading,impact,modelling
Defining the role of FBXW7 in intestinal epithelium regeneration (FBXW7-InReg)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2025-02-11
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: SIGNED

Inflammatory bowel disease (IBD) is a severe disorder affecting millions of people in Europe, characterised by chronic flares of intestinal inflammation and causing tissue loss or malfunction. Currently, the available treatments can only reduce symptoms. New regenerative therapies promoting epithelial functionality are highly needed. Several studies report how upon damage, progenitors or more committed cells re-acquire stemness properties and foetal-like signatures to restore intestinal homeostasis. However, it is still unclear how such regenerative response is modulated and how cells revert to their adult state. Preliminary data from the host lab indicate that loss of expression of FBXW7 protein, member of a E3 ubiquitin ligase complex, reinforces cells in the foetal-like state. Interestingly, FBXW7 mutations are under positive selection in IBD patients. Thus, I propose that upon injury, cells lacking FBXW7 maintain a foetal-like state, where they are refractory to terminal differentiation, increasing the risk of aberrant tissue restoration. To test my hypothesis, I will exploit state-of-the-art in vivo and in vitro models of intestinal regeneration and make use of forefront technologies, such as CRISPR, high-content imaging, mass spectrometry and single cell RNA sequencing. This will allow me to 1. characterise FBXW7 impact on intestinal regeneration, 2. define FBXW7 mode of action in human intestinal cells, and 3. identify FBXW7 substrates as potential targets to restore tissue homeostasis. By addressing these points, it will be possible to obtain key insights into the mechanism of intestinal regeneration and identify ways to efficiently induce and control tissue repair in IBD patients, avoiding the expansion of unrestrained proliferating foetal-like cells. Importantly, leading this action, I will acquire a new set of technical and transferrable skills and reach a deep scientific maturity that will grant me a successful career as future group leader.

Keywords: intestinal epithelium,regeneration
RE-assembly and COMpetition during Biotic INterchangEs: consequences of old invasions on the evolutionary and ecological history of biotas (RECOMBINE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Australia,France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-02-01
End date: 2024-04-10
Duration (months): 36.0
Total project cost (EUR): 263827.2
EU funding (EUR): 263827.2
Participants: 2
Project status: SIGNED

Biotic interchanges are invasions of species from one biota to another. During the Cenozoic, tectonic and glacial dynamics led to subsequent large-scale biotic interchanges that are considered key events for shaping the current global biodiversity. Here I propose to study the migration, speciation and extinction of terrestrial vertebrates at global scale to understand the reassembly of communities as landmass connectivity changed. I will use recently available data (such as comprehensive phylogenies calibrated with the fossil record and tectonic reconstructions) with new methods in macroevolutionary analysis. I propose this MSCA as a 3-year GF. One of the most cited research groups in the study of biogeography and evolution of vertebrate diversity (ANU, Australia) will host me during the outgoing phase, where data preparation, analyses and training in macroecology will be conducted. A secondment at the beginning of the outgoing phase, and the third year of return to the host organisation (ENS, France), with a leading group in macroevolution, will be devoted to training me in phylogenetic inference methods. I will gain expertise in macroecology and macroevolution, complementing my background in community ecology, ecophysiology and phylogeography, opening up the best career possibilities for me in the fields of biodiversity research and providing new collaboration opportunities for the host organisations. As my proposed approach is novel and the questions addressed are of high concern, the MSCA is expected to provide important advances in our understanding of biodiversity patterns as well as to promote new scientific pathways in the fields of macroecology, macroevolution and historical biogeography. A series of outreach activities will also contribute to public education and awareness of the unique biodiversity that we have in every continent and how historical invasions contributed to it.

Keywords: macroevolution,phylogenetics,invasion ecology
NON-WESTERN MILITARY INTERVENTIONS AND THE CHARACTER OF WARFARE IN THE EUROPEAN PERIPHERY (NWICWEP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

While Western countries regularly intervene militarily abroad, recent years have seen increasing levels of military intervention by non-Western authoritarian and weakly-democratic states in the EU periphery. Non-Western interventions profoundly impact the security dynamics of an increasingly fragile EU neighbourhood. Despite this, the patterns and character of resulting conflicts are ill-understood, especially compared to recent conflicts involving Western states (on which much of the recent conflict literature is based). This project will conduct a highly original comparative analysis of three EU-periphery conflicts (Ukraine, Yemen and the West African Sahel) that have seen the involvement of four of the most militarily active non-Western states in the wider EU neighbourhood (Russia, Saudi Arabia, and Nigeria/Chad respectively). The fellowship will advance knowledge of: 1) how the character of conflict involving non-Western military powers differs from general conceptualizations of contemporary warfare (and each other); and, 2) how the character of these conflicts is comprehended strategically both by key state actors involved, and by Western security actors (EU and NATO). Such a project is timely given rising levels of conflict in the EU periphery and necessary given the absence of comparative enquiry into the evolving character of armed conflict across the wider EU neighbourhood. Through a mixed-methods analysis of three conflicts of critical importance to the EU, this project will offer innovative research findings on the causes, politico-military strategic logics, military practice and potential resolution of contemporary non-Western war that will support the EU’s recently-developed 2016 ‘Global Strategy’ for the EU Foreign and Security Policy.

Keywords: military intervention,character of war,warfare,conventional,unconventional,non west,authoritarian,asymmetry,connectedness,utility of force,democracy
Quantifying atmospheric ice nucleating particle (INP) concentrations via advances in measurement techniques and field studies of ice nucleation (ATM-METFIN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-05-01
End date: 2019-04-30
Duration (months): 24.0
Total project cost (EUR): 175419.6
EU funding (EUR): 175419.6
Participants: 1
Project status: CLOSED

The focal point of the research proposal is to combine the current technological advancement and scientific questions regarding the unknowns of atmospheric ice nucleation. Ice nucleation is an important pathway for cloud formation and initiation of precipitation, therefore playing a significant role in the Earth’s hydrological cycle and energy and radiative balance. Several questions pertinent to ice nucleation remain unanswered, partially due to gaps in instrumental technology and lack of ambient measurements. The proposed work primarily focuses on the mechanisms of ice nucleation in the atmosphere, more specifically the number, physics and chemistry of biogenic and anthropogenic aerosol particles able to act as ice nucleating particles (INP). Field measurements with technological improvements to the existing Portable Ice Nucleation Chamber (PINC) are planned. One of the goals is to continue the time series measurements of INP parameters at the Izaña Observatory in Tenerife, where measurements have been ongoing since 2013 by the host institution. Since the INP concentration exponentially decreases with increasing temperature, and it is the warmer sub-zero temperatures that are more relevant for the initial ice formation in mixed-phase, the goal is to extend the measurements of INP parameters at the Izaña Observatory in Tenerife to temperatures above −30°C. Using additional instrumentation in the field, the role of mineral dust, particles of anthropogenic origin and marine primary biogenic particles as potential INP will be investigated in more detail. From a technical perspective, the work will concentrate on lowering the detection limits of PINC and on improving its ability to differentiate between water droplets and ice crystals. These improvements will allow measuring INP at warmer sub-zero temperatures and in immersion/condensation mode, both of which are more relevant for the first ice formation in supercooled clouds than our current measurements.

Keywords: ice nucleation,atmosphere,mineral dust,field measurements
Airbag bicycle helmet based on One Piece Woven technology (The Invisible Helmet)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Sweden
Call: Small business innovation research for Transport (H2020-SMEINST-2-2015, 2015)
Start date: 2016-04-01
End date: 2018-03-31
Duration (months): 24.0
Total project cost (EUR): 1967770.0
EU funding (EUR): 1377439.0
Participants: 1
Project status: CLOSED

Cycling is a crucial mode of transport in the common European challenge of making transport sustainable: cycling is energy efficient, environmentally friendly and very suitable for short distances. The use of helmet is not widely accepted by urban cyclists due to practical reasons, they are uncomfortable, cumbersome to carry around, look hideous, make sweat and ruin personal style. Hövding represents a head protection for cyclists unlike any other product on the market – an airbag for cyclists. Compared with traditional helmets, Hövding is more than three times better shock absorbance, can withstand multiple mpacts in one accident, reduce head rotation, provides much larger protection area and stabilizes head and neck in the accident. Hövding is easy to fold and bring in bag, discrete, works with a hat. Hövding has been sold during around 3 years. Now we focus on expanding from initial test sales in Sweden to successive rollout across Europe. However some limitations such as our quite manual manufacturing process impede us to scale up our product and meet our growth ambitions. The overall objective of our business innovation project is to automatize the manufacturing process of our airbag for cyclists called Hövding with the aim of scale-up and reduce production costs. To this end, airbag will be designed and manufactured in one piece with woven seams eliminating the need of conventional sewing. We also want increase the add-value of our airbag add Bluetooth Low Energy connectivity and developing an outer shell based on nanotechnology textiles to obtain superior lightweight, good water and stain repellent properties. Hövding addresses a market of an estimated 150 million adult cyclists in Europe alone and clearly contributes to EC policies intended to improve road safety offering a more safety solution to traditional helmets. With this business innovation project we want to establish Hövding as a novel product category – The No.1 head protection for cyclist

Keywords: vulnerable road users,urban transport,road transport injuries,airbag,one piece woven,technology,bluetooth low energy
SparCity: An Optimization and Co-design Framework for Sparse Computation (SPARCITY)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Public-private partnerships
Destination: European High Performance Computing
Action type: Research and Innovation actions
Partnership: EuroHPC (Art-187)
Countries involved: Germany,Türkiye,Norway,Portugal
Call: Extreme scale computing and data driven technologies (H2020-JTI-EuroHPC-2019-1, 2019)
Start date: 2021-04-01
End date: 2024-03-31
Duration (months): 36.0
Total project cost (EUR): 2605472.5
EU funding (EUR): 1302736.25
Participants: 6
Project status: SIGNED

Perfectly aligned with the vision of the EuroHPC Joint Undertaking, the SparCity project aims at creating a supercomputing framework that will provide efficient algorithms and coherent tools specifically designed for maximising the performance and energy efficiency of sparse computations on emerging HPC systems, while also opening up new usage areas for sparse computations in data analytics and deep learning. The framework enables comprehensive application characterization and modeling, performing synergistic node-level and system-level software optimizations. By creating a digital SuperTwin, the framework is also capable of evaluating existing hardware components and addressing what-if scenarios on emerging architectures and systems in a co-design perspective. To demonstrate the effectiveness, societal impact, and usability of the framework, the SparCity project will enhance the computing scale and energy efficiency of four challenging real-life applications that come from drastically different domains, namely, computational cardiology, social networks, bioinformatics and autonomous driving. By targeting this collection of challenging applications, SparCity will develop world-class, extreme scale and energy-efficient HPC technologies, and contribute to building a sustainable exascale ecosystem and increasing Europe’s competitiveness.

Keywords: sparse computation,graph algorithms,performance modeling,co design,performance tuning,sparse linear algebra,exascale computing,hardware accelerators,ipus,gpus
Immigrant's integration in several EU and non-EU countries: a time-use approach (TIMEUSE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-02-01
End date: 2023-01-31
Duration (months): 24.0
Total project cost (EUR): 178320.0
EU funding (EUR): 178320.0
Participants: 1
Project status: CLOSED

TIMEUSE aims to study the integration of immigrants for a wide range of EU and non-EU countries, by applying a new approach based on the time immigrants and natives allocate to daily activities. This objective will be achieved by: 1) investigating the differences between immigrants and natives in participation and in the time spent in integrating activities using parametric methods. In particular, the analysis will focus on differences between sub-groups of immigrants based on gender and other characteristics; 2) developing new metrics that analyse the relationships between integrating activities and how individuals distribute the time across activities. The analysis of the relationships between activities allows us to better understand deviations from desirable behaviour and inform policy actions aimed at removing constraints. The research will be based upon the use of highly detailed data on the time-use of a large sample of immigrants and natives residing in several EU countries, USA and Canada. In order to achieve this objective, I will be based at CESSMIR, an excellent centre in migration studies that is part of the Ghent University; an internationally renowned institution ranking among the 100 best universities in the world. Here, I will be trained in innovative and interdisciplinary methods applied to migration studies under the supervision of Prof. Glenn Rayp. Additional training on data management techniques will be provided by my secondment at CTUR, a world-leading centre that manages the data I will use in the analysis. The successful completion of training and research under TIMEUSE will greatly benefit my future career prospects in academia.

Keywords: immigration,time use,integration of migrants,network analysis
Biped and Autonomous: Bone microarchitecture of the Youngest, PAthological and Cultural Effects (BABY PACE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2023-09-30
Duration (months): 36.0
Total project cost (EUR): 251002.56
EU funding (EUR): 251002.56
Participants: 2
Project status: CLOSED

In this prosperous period in analyzing cultural impacts on human biology thanks to cutting-edge technologies, BABY PACE postulates bone microstructures as a way to approach human cultures. It aims to find how different cultural environments, in both normal and pathological contexts, have an impact on bone development during bipedal walking acquisition of the infants of the past. Bone microstructures, useful for human evolution issues, can also respond to the urgent need to understand development in living infants, impossible to get with micro-computed tomography. Cultures imply various definitions of important social steps. They influence as well the place of children in their society as their locomotor development. This milestone leads to variations in body use and so in bone biomechanics to which bone microstructures respond by adapting to them. The two BABY PACE’s phases (24 months, USA - 12 months, Italy) will for the first time allow developing a controlled model of the normal development of bone microstructures during the biped acquisition, based on the Certosa collection of identified non-adult skeletons. Comparisons between cultures, normal and pathological developments, and during a cultural transition will be performed against this model. Bone properties variations will highlight different developmental trajectories according to groups. BABY PACE is a strong base for projects could answer to society or public health issues related to desired or endured cultural changes. This international interdisciplinary project part of medical, life and past sciences will give to the Researcher the full background and maturity to be a recognized anthropologist, specialized in bone ontogeny. It responds to EU research priorities through the transfer of gained knowledge and partnerships development with leading experts in bone microstructures research. Not only is it improving employability and career prospects, but also contributes to the EU's competitiveness and growth.

Keywords: micro computed tomography,biomechanics,ontogeny,trabecular bone,cortical bone,microarchitecture,locomotor behaviors