Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Clean and low costs paper-based batteries for powering single use disposable diagnostic devices. (CLEANFUEL)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-12-01
End date: 2018-04-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Fuelium is one of the few companies worldwide involved in the emerging field of paper-based batteries. The company was born upon the opportunity identified in our patented technology, as an eco-friendly power source for disposable single-use electronic analytical devices. In the CLEANFUEL project we seek completing all the activities required for the successful market implementation of our paper batteries in disposable in-vitro diagnostic devices (also known as disposable Point-of- Care or PoC tests). We have selected this niche as the first market application of our patented battery technology because of a synergistic confluence of the next factors: a) the medical devices market is the segment where disposable electronics are gaining the highest market share and b) our technology is perfectly suited to provide its breakthrough advantages in these specific applications. Hence, we consider the CLEANFUEL project as the one that will boost our company´s growth in the shortest time period. Fuelium technology has been designed to power electronic single use devices, such as portable in-vitro diagnostics (IVD), with the breakthrough advantage that they that can be safely disposed without removing them from the product they are powering. Compared with button batteries where, in general, the amount of energy stored is over-dimensioned for the PoC device necessities, our batteries only generate the indispensable amount of energy. In addition, no toxic waste is generated, so the requirements for complex and expensive recycling processes are avoided. Our batteries’ materials and fabrication processes are fully compatible with those employed in most of the single use PoC diagnostic devices. This fact will reduce manufacturing and integration costs of our batteries in stand-alone, self-powered devices.

Keywords: batteries,point of care,mobile energy sources
SolarGaps - Energy generating solar smart window blinds (SolarGaps)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Ukraine
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-11-01
End date: 2018-02-28
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

With the constant growth of population in the world, the demand for electricity is rising. The biggest electricity consumers are buildings. In EU heating and cooling in the buildings and industry accounts for 50% of the EU’s total energy consumption. However, generating electricity from conventional sources of energy increases the greenhouse effect and escalate the environmental problems on Earth. One of the existing solutions to these problems are alternative sources of energy, in particular, solar. However, the existing solar solutions have several problems: solar panels are too expensive and can be mounted only on the roof or flat surfaces, and billions of city residents don't have access to roofs, or private land. Energy generation from vertical surfaces (such as solar window technology) is still on prototyping stage and has low efficiency. SolarGaps came up with the innovative solution – the company developed first in the world solar smart window blinds – a device that combines a shading appliance (venetian blinds) with solar panels, which allows generating electricity for further storage or use, as well as protecting the room from overheating, and the windows from poor weather conditions. The electricity, generated with SolarGaps, will allow to reduce external electricity consumption by up to 70% To ensure successful commercialization, in Phase 1 of SME Instrument, SolarGaps intends to develop an elaborate feasibility study for SolarGaps blinds commercialization that would include a thorough market research, dealership network development, a business plan with an extensive financial, pricing, and IPR strategy. This will help the company to have a more detailed vision of the target markets, improve the design and features of the product to meet the users’ needs, build quality business partnerships, and tailor pricing & sales strategies to capture the biggest market share possible.

Keywords: smart blinds,solar blinds,renewable energy,solar energy,solar panel,energy efficiency,energy generation,smart home,home automation,energy management,blinds and shades
Theory for A Unified descRiption of nUclear Structure (TAURUS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-12-02
End date: 2021-12-01
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: CLOSED

Ordinary matter is made of atoms and atoms are made of electrons surrounding a very tiny and fascinating object, the atomic nucleus. At the same time, the atomic nucleus is a physical system composed of two types of particles, protons and neutrons, that are interacting through intricate nuclear interactions, and, in the case of protons, through the electromagnetic interaction. Typical energies and sizes of this system require for its study the use of quantum many-body techniques. The main scientific goal of the present action is to provide a microscopic, universal and reliable theoretical description of the atomic nucleus. This ambitious objective will be achieved by developing: 1. Theoretical tools that combine state-of-the-art first- principles (ab-initio) nuclear interactions with the two most widely used quantum many-body techniques in Nuclear Physics, namely, the interacting shell model and the self-consistent mean-field and beyond-mean-field approximations. 2. State-of-the-art software and high performance computing to implement and use these techniques to produce valuable theoretical data that can be useful to nuclear experimentalists and astrophysicists. Pursuing this objective, the experienced researcher (ER) will acquire new scientific, managerial, dissemination, mentoring and cultural skills through advanced training that will boost his career possibilities both in academia and industry. Furthermore, this action is mutually beneficial because it opens a new line of research within the host group devoted to nuclear ab-initio methods. These topics are considered as the most important challenges to Nuclear Theory for the next decade. Therefore, this action will foster the international visibility and attractiveness of both the ER and the host group.

Keywords: energy density functionals,ab initio,large scale shell model,effective field theory,collective and single particle excitations,gamma and beta decays
Evaluation of 22 nm Fully-depleted Silicon-on-insulator technology for Space (EFESOS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling European competitiveness, non-dependence and innovation of the European space sector
Action type: Research and Innovation actions
Countries involved: Austria,Spain,Italy,Belgium
Call: Technologies for European non-dependence and competitiveness (H2020-SPACE-2018, 2018)
Start date: 2019-12-01
End date: 2022-11-30
Duration (months): 36.0
Total project cost (EUR): 3384448.75
EU funding (EUR): 3384448.75
Participants: 5
Project status: SIGNED

The EFESOS project aims to develop and evaluate a cutting-edge ASIC technology for space applications. More specifically, departing from the characterization of the commercial technology, a radiation-hardened-by-design digital library and a set of complex analog IP cores (ADC, DAC, SERDES and PLL) will be implemented using the 22FDX process from Global Foundries, available at their production facility in Dresden (Germany). A complete electrical, environmental (radiation) and reliability validation of the technology will be performed, and the resulting fully-European design flow will be evaluated according to the ESCC standards with a representative sample chip. The 22FDX is a 22nm Fully-Depleted SOI technology providing up to 40% die scaling relative to the standard 28nm node, nearly 70% lower power than 28nm and similar power efficiency to FinFET technology. EFESOS responds to the increasing demand of the European space industry of more integrated ASICs at higher performance, and greatly contributes to the strategic goal of achieving non-dependence on critical technologies. The project will provide Europe with a technical capability beyond the current state-of-the-art, thus becoming a global reference in space microelectronics.

Keywords: 22 nm fd soi process,dare,asic,rad hard by design,asic rh design platform,design kit,design library,hssl,serdes
Highly efficient protein rich biofertilizer, 100% spirulina based, for agricultural yield increase and crop quality traits enhancement (agroCYAN ECO)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for sustainable and competitive agriculture, forestry, agri-food and bio-based sectors (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-12-01
End date: 2018-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

A doubling in global food demand projected for 2050 due to rising poses huge challenges for the sustainability of food production systems. To satisfy the growing demand, the only feasible solution is to increase productivity on existing agricultural land. Traditionally, growers have made use of synthetic fertilizers for production increase but these products pose serious risks on ecosystems, living animals and human health. In this context, biofertilizers emerge as an efficient alternative to traditional fertilizers, able to boost crops yields and maximize the quality traits of fruits and vegetables but without the harmful effects. In this proposal, the Spanish agro-biotechnology Jaro Innovaciones presents agroCYAN ECO, a liquid biofertilizer, phosphate-free, obtained by enzymatic hydrolysis of the spirulina biomass, a cyanobacteria highly rich in L-amino acids of easy absorption, phytohormones and other nutritive substances. When our biofertilizer is applied to plants, crop yields are increased up to 33% and the quality traits of the harvested products are significantly improved since agroCYAN ECO favours roots’ development, stomata’s opening and nutrients’ acquisition. agroCYAN ECO is the cheapest solution among its competitors and can be applied to any horticultural product and to vines, citrus trees, olive trees, etc. agroCYAN ECO has been especially formulated for its use in organic agriculture, having been certified to this end. Its application can be done as a foliar spray, in fertigation or for the preparation of nutritive solutions, reducing the doses of the other treatment products up to 20%. The main risk for agroCYAN ECO commercialization in the European market is the lack of a harmonized regulation, although the current fertilizer regulation is being revised now. Thus, in the Feasibility Study we will pay special attention to regulatory issues since they will be decisive for our commercialization strategy.

Keywords: spirulina,cyanobacteria,microalgae,biofertilizer,amino acids,phytohormones,enzymatic hydrolysis,protein hydrolysates,horticultural crops
Conques in the Global World. Transferring Knowledge: from Material to Immaterial Heritage (CONQUES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Germany,Italy,France,France,Czechia,United States
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2020, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 943000.0
EU funding (EUR): 855600.0
Participants: 8
Project status: SIGNED

Conques is visited annually by thousands of tourists and walking pilgrims. It is a unique site of cultural heritage preserving outstanding visual, material, and ritual cultures from the 9th to the 21st c. Regretfully, its cultural significance contrasts with the lack of comprehensive scholarly attention. Its date, level of reconstruction, and place in the story of the history of art have all been disputed. This is alarming, since a complex understanding of this unique site is indispensable for both the effective research of scientific communities and the expansion of interest among public audiences. The CONQUES project emerges from an ongoing story of exchanges and interactions between scholars, institutions, and fields of research. The overall goal of CONQUES is to promote the first interdisciplinary integrative research on the site, combining the expertise from five different fields, and thus to increase its currently marginal role in public discourse. Our aim is to reconstruct crucial elements in the development of European culture through investigating major stages in the medieval construction of Conques, but also to reimagine and tell the story of the 19th and 20th century “re-invention” of the European Middle Ages. We will break new ground in different disciplines by employing both classic and experimental methods. The key outcomes of this integrative analysis will include: a) a long overdue scientific monograph; b) the creation of a sustainable collaborative research platform working at the crossroads of different disciplines; c) an integrative protocol of research, which will be transferable and exploitable on other sites of the shared medieval European culture; d) the creation of a sustainable public outreach program sharing the results of this multidisciplinary research with a wide audience through exhibitions, and public lectures, and widely disseminated didactic books for the public and tourists.

Keywords: conques,sacred space,medieval art,architecture,material culture,rituals,liturgy,pilgrimage,cultural heritage,global middle ages,archaeometry,history of scholarship,auralization,embodiment
Psychiatric Ratings using Intermediate Stratified Markers 2 (PRISM 2)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Public-private partnerships
Destination: Innovative Medicines Initiative 2
Action type: Research and Innovation actions
Partnership: IMI2 (Art-187)
Countries involved: Italy,Germany,Spain,Germany,France,Netherlands,Netherlands,Netherlands,Netherlands,United States,Netherlands,United Kingdom
Call: Restricted Call to maximise impact of IMI2 JU objectives and scientific priorities (H2020-JTI-IMI2-2020-22-single-stage, 2020)
Start date: 2021-06-01
End date: 2024-05-31
Duration (months): 36.0
Total project cost (EUR): 7894553.69
EU funding (EUR): 3980906.25
Participants: 18
Project status: SIGNED

The current nosology of neuropsychiatric disorders provides a pragmatic approach to diagnosis and treatment choice but lacks reference to quantitative biological underpinnings of disease. This weakness impedes innovative drug development. To test whether a quantitative biological approach to the understanding and classification of neuropsychiatric disorders is both feasible and useful the PRISM 1 consortium was formed by academics, SMEs, patient organizations, regulators, ECNP, and EFPIA partners. PRISM 1 has now successfully identified quantitative biological parameters related to diagnosis (Schizophrenia (SZ) and Alzheimer Disease (AD)) as well as to social functioning irrespective of diagnosis. From the relationships between social function, neuroimaging, and cognitive endpoints a new neurobiological framework has emerged now needing further validation. Genetic studies of social functioning outcomes revealed known and novel loci for this phenotype. In addition, a preclinical test battery was developed, based on homologs of the clinical paradigms, to allow effective back-translation and a deepening of our neurobiological knowledge. Finally, a novel digital tool for assessing social function provided a novel, objective characterization that transcended the initial diagnostic classification and the digital readouts were associated with other study parameters. To build on outcomes of PRISM 1, PRISM 2 has three objectives. First, to determine the reproducibility of the transdiagnostic and pathophysiological relationship between DMN integrity and social dysfunction in SZ and AD that emerged from PRISM 1 and determine its potential to generalise to Major Depressive Disorders. Second, to test the causality between the quantitative variation in DMN integrity and social dysfunction. Third, to translate and communicate project results to the benefit of stakeholders, such as regulators, patients and their families, and health care providers.

Keywords: alzheimer disease,schizophrenia,major depression,transdiagnostic,translational neuroscience,digital biomarkers,quantitative biology
DEEP BRAIN PHOTONIC TOOLS FOR CELL-TYPE SPECIFIC TARGETING OF NEURAL DISEASES (DEEPER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Partnership: Photonics (cPPP)
Countries involved: Germany,Germany,Israel,Spain,Italy,Italy,Switzerland,Switzerland,Belgium,France,Czechia,United Kingdom
Call: Disruptive photonics technologies (H2020-ICT-2020-2, 2020)
Start date: 2021-01-01
End date: 2025-04-30
Duration (months): 52.0
Total project cost (EUR): 5797506.25
EU funding (EUR): 5797506.25
Participants: 12
Project status: SIGNED

While brain disorders have different etiology and stem from distinct molecular and cellular dysfunctions, due to limitation in current technology they all share an incomplete understanding of the anatomical and functional alterations occurring in hard-to-access deep regions of the brain. DEEPER aims at tackling this fundamental challenge by developing an entire new class of photonic tools for imaging and manipulating neuronal activity in the deep brain with unprecedented penetration depth, resolution, sensitivity, specificity and depth of focus. Technology development in DEEPER will be driven by medical expertise and market requirements and it will be organized in three pillars focusing on: i) novel high-efficiency molecular sensors and actuators; ii) minimally invasive probes for monitoring and perturbing large populations of cells; iii) next generation multiphoton microscopes and microendoscopes. In a fourth pillar, this technological platform will enable a number of clinically relevant experiments which will contribute to reveal the molecular and cellular dysfunctions underlying the pathogenesis of specific neurological (addiction, chronic pain, Alzheimer’s disease) and psychiatric disorders (depression, schizophrenia, and autism). By shedding new light on the pathogenesis of disorders, which dramatically touch the lives of millions, DEEPER has the potential to profoundly impact our society. Moreover, in DEEPER technologists, neuroscientists, clinical and pre-clinical experts will bring the results from laboratory research to market supported by the SMEs in the consortium and by the companies and experts in the advisory board. This will make the translation and exploitation of the DEEPER technologies fast and effective, building a value chain with strong translational appeal that will strengthen Europe’s industrial position in the biophotonics market for optical neural interfaces, microscopy, and microendoscopy.

Keywords: neurophotonics,optogenetics,photoswitchable neurotransmitters,fluorescent neural activity indicators,optical neural interfaces,fiber photometry,optrodes,multiphoton microscopy,microendoscopy
Innovations in Neural Conceptual Representation: Exploring Aspects of Semantics (INCREASE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-10-15
End date: 2018-10-14
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Semantic representation –the knowledge that we have of the world– is an essential component of our mind whose nature can be inferred from similarity measures, which we use every day to compare entities on the basis of their meaning. Many research efforts have been made to understand our knowledge, proposing that it could be based upon data deriving from our sensorimotor experience or from any sort of regularity in spoken and/or written language. Recently, models combining these two data sources obtained semantic representations that are more informative and similar to human ones. However, 1) what information is used to represent meaning and 2) the way our brains organize semantic representations still remain hot topics of debate in the field. The project aims to address these queries, by investigating, for the first time, the relation between semantic representations at three different levels: behaviour, models and brain activity. We will derive similarity measures and combined similarity models using different data sources (text corpora, semantic feature norms, ratings studies). Next, in an fMRI study, adult English speakers will perform implicit (lexical decision) and explicit (categorization) tasks. We will use (1) a state-of-the-art technique (Representational Similarity Analysis) that has heralded a new research era in the study of semantics since it allows one-to-one mappings between patterns of brain-activity measurement, behavioural and computational models, and (2) dimensionality-reduction approaches. Results will provide new knowledge on the nature of semantic structure: they will allow a better characterization of different similarity measures, adjudicating between the different similarity models and behavioural data as well as identifying differences between similarity models linked to differences in neural activity. This will reveal the different neural contributions to different aspects of meaning, opening up new research agendas.

Keywords: concepts,semantic representation,similarity,experiential view,distributional view,combined models,fmri,neural underpinnings,representational similarity analysis,categorization