Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The advanced eco-technology manufacturing of materials as a way of competitiveness for Europe's industrial business (FELTWOOD)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

EU furniture industry is facing enormous competition from countries having low production costs. China is now the largest furniture exporter to the EU, accounting already for over half of total furniture imports to the EU and growing rapidly. To avoid this, and keep added value, turnover, earnings and employment in Europe, production costs must be more competitive to continue producing high-quality furniture at competitive prices. Access to sourced raw materials, the cost and complications of harvesting wood in the EU affect all segments of the value chain of the furniture sector. Fluctuations in raw material prices and problems relating to availability of products respecting environmental, sustainability and technical standards and regulations are factors upstream the value chain that negatively impact furniture production. An innovative ecological materials and industrial company, Feltwood Ecomateriales, S.L., has developed the world´s first production technology able to get 100% vegetal fibre industrial raw material from agricultural organic waste and use it to produce panels for furniture industry. This novel material is a real alternative for wood-based panels used by furniture manufacturers nowadays. It is cheaper than wood, not subject to EU wood related directives and does not use any adhesive like wood-based panels. Feltwood´s initial commercialisation plan is based on four pillars: product, price, promotion and target countries (Spain, Portugal, France, Germany and Italy). The amount of European furniture companies belonging to our target markets are 67,000 Italian, 14,000 Spanish, 52,000 German, 38,000 French and 2,072 Portuguese. This planning will be executed in collaboration with our key-stakeholders, knowing that Feltwood has protected it through an industrial patent proposal(nº. IRTA_R-12-00-01).

Keywords: wood,agricultural organic waste,industrial process,cellulose molecules,ecological material
A European standardization framework for data integration and data-driven in silico models for personalized medicine (EU-STANDS4PM)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Health care provision and integrated care
Action type: Coordination and support actions
Countries involved: Germany,Germany,Germany,Germany,Italy,Germany,Germany,Germany,Germany,Lithuania,Sweden,Belgium,Netherlands,Denmark,United Kingdom,United Kingdom
Call: Data integration and data-driven in-silico models for enabling personalised medicine - a European standardization framework (H2020-SC1-2018-Single-Stage-RTD, 2018)
Start date: 2019-01-01
End date: 2022-12-31
Duration (months): 48.0
Total project cost (EUR): 2042411.25
EU funding (EUR): 2042411.25
Participants: 17
Project status: SIGNED

The capacity to generate data in Life Sciences and health research with modern omics and imaging technologies has increased many orders of magnitude in the last decade. In combination with patient/personal derived data such as electronic health records, patient registries and -databases, as well as life style information this Big Data holds an immense potential for clinical applications, especially for in silico personalized medicine approaches. However, and despite the ever progressing technological advances in producing data, the exploitation of Big Data information to generate new knowledge for medical benefits, while guaranteeing data privacy and security, is lacking behind its full potential. A reason for this obstacle is the inherent heterogeneity of Big Data and the lack of broadly accepted standards that allow interoperable integration of heterogeneous health data to perform analysis and interpretation for predictive in silico modelling approaches in health research such as personalized medicine. Further obstacles are legal issues surrounding the use of personal data. To overcome these obstacles, we will establish a pan-European Expert forum with two main objectives: (i) to assess and evaluate national standardization strategies for interoperable health data integration (such as omics-, disease-focused-, clinical-/treatment- or healthcare- and socioeconomic-/lifestyle-data) as well as data-driven in silico modelling approaches and (ii) to harmonize and develop universal (cross-border) standards as well as recommendations for in silico methodologies applied in personalized medicine approaches. This pan-European Expert Forum —the EU-STANDS4PM consortium— has the overarching aim to bundle transnational standardization guidelines for in silico methodologies in transnational and clinical research to unfold the potential of personalized medicine.

Keywords: standards,data integration,in silico modelling,personalized medicine,european framework
Marine robotics research infrastructure network (EUMarineRobots)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Integrating activities and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Ireland,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Italy,Spain,Ireland,Italy,Norway,Croatia,Belgium,France,United Kingdom,United Kingdom,United Kingdom,Portugal,Portugal
Call: Integrating Activities for Starting Communities (H2020-INFRAIA-2017-1-two-stage, 2017)
Start date: 2018-03-01
End date: 2021-11-30
Duration (months): 45.0
Total project cost (EUR): 4998736.75
EU funding (EUR): 4998736.75
Participants: 28
Project status: CLOSED

Our oceans are the least-explored region of planet Earth. Protection and sustainable development of ocean resources presents formidable challenges. Robots will play an increasingly key role in the near future and this role will expand and become more challenging as we extend into deeper, remote and hostile marine environments. Europe leads in many aspects of maritime, but lacks well integrated and coordinated oceanic robotic infrastructure or presence. The marine-robotics industry is growing rapidly. It is a crucial high-value/high-cost sector with considerable entry-barriers to R&D. The full growth potential of this industry will be greatly enhanced with access to shared robotic research infrastructure. EUMarineRobots (EUMR) proposes an access-infrastructure for the deployment of a full-range of aerial, surface and sub-surface marine robotic assets, the combined value of which is far greater than the sum of their parts. EUMR will open transnational access to significant national marine robotics R&D assets across Europe. The EUMR consortium comprises 15 partners from 10 countries who, collectively, can deploy a comprehensive portfolio of marine robotic assets with required associated support assets and expertise. The network is a strong and balanced grouping of globally distinguished key players with diverse, track-record of excellence across marine / robotic sectors. Partners are members of a wide variety of existing networks, and research infrastructure collaborations both formal and informal across Europe and the world. EUMR is a first stage in aggregating these networks and assets as world-leading for support and growth of a strong community of practice in marine robotics and marine.

Keywords: marine robotics,autonomous underwater,surface and air vehicles,remotely piloted vehicles,command and control,virtual facilities,big data,sensors and communications,and systems of systems ri
High performance laser micro drilling machine for large Hybrid Laminar Flow Control suction panels (HyperDrill)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Germany,Spain
Call: High throughput micro drilling (HTMD) system (H2020-CS2-CFP04-2016-02, 2016)
Start date: 2017-06-01
End date: 2020-12-31
Duration (months): 43.0
Total project cost (EUR): 1968832.5
EU funding (EUR): 1968832.5
Participants: 2
Project status: CLOSED

The main goal of the Hyper-Drill project is the development of a laser micro-drilling machine prototype for the manufacture of Hybrid Laminar Flow Control (HLFC) titanium suction panels with dimensions up to 5 m x 2 m and able to fulfil the requirement of a production rate ≥ 300 holes/s. This includes the creation of knowhow in producing such kind of structures as a basis for the industrial manufacturing of HLFC leading edges. For this purpose, firstly an optimization of the most suitable laser based technologies and processing parameters for the micro-drilling process will be carried out. The single pulse micro-drilling (SPMD) and the percussion micro-drilling (PMD) techniques are the covered technologies in this proposal for the micro-drilling of titanium sheets. In contrast to other approaches, both techniques have been widely investigated and are able to provide the requested results described in the Call by demonstrating at the same time feasibility on large Ti panels. Obtained production rates with these methods are above 400 holes per second. Several technical as well as economical aspects will be analysed in order to determine the most suitable technique for different specifications and conditions. A machine prototype equipped with both micro-drilling techniques will be designed, assembled and tested for production of 5 x 2 m Ti panels. A tentative design of the prototype based on the Consortium previous experiences and expertise is provided. The proposed design allows future upgrades for further increasing production rates beyond those requested in the Call for proposals. Several features for quality inspection of the micro-holes such as machine vision systems as well as quality control by in-situ monitoring the laser working distance have been included. Finally, the prototype will be optimized and commissioned at the Topic Manager facilities.

Keywords: hybrid laminar flow control,laser micro drilling,micro drilled ti sheets,high throughput micro drilling,micro holes
Magnetic Resonance Shimming Applications with Near-magnet Equipment (mrSANE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-10-01
End date: 2019-03-31
Duration (months): 18.0
Total project cost (EUR): 149937.0
EU funding (EUR): 149937.0
Participants: 1
Project status: CLOSED

Magnetic resonance (MR) imaging and spectroscopy critically relies on the homogeneity of the main field. Despite of the best technological efforts magnetic field in MR examinations cannot be made homogeneous due to the presence of the object of investigation – the human or an animal – in the magnet. Heterogeneous and unique distribution of tissues with their characteristic magnetic susceptibilities requires the process of field homogenization, termed shimming, to be performed on a subject-by-subject basis. Shimming subsystems of the clinical MRI devices often show insufficient, leading to sub-optimal image quality and even failing diagnosis. Furthermore, numerous emerging methods, while showing their great potential in research settings, require even better shim fidelity. We therefore identify improved shimming as a current unmet need in MRI. Add-on hardware for more reliable shimming will greatly aid MRI research especially in the field of ultra-high imaging, such as 7T and above. A wider availability of improved shimming capabilities in the clinical machines will accelerate the transition of a multitude of current promising scientific applications of MRI to the clinical practise, allowing for a more precise diagnosis and improved patient outcomes. The current project will aid a wider spread of the emerging shimming techniques, not based on spherical harmonics. As these techniques require a higher number of electrically controlled driving channels, the project addresses the scalability problem of the current shim amplifier technology by bringing the equipment closer to the magnet and eliminating a substantial number of expensive and error-prone components. It is therefore to expect that the novel system topology will make future MRI devices cheaper and more reliable, reducing the production, citing and maintenance costs. Collaboration with a European power amplifier manufacturer will ensure market-driven developments and a rapid dissemination of the results.

Keywords: magnetic resonance,shimming,magnetic resonance imaging,magnetic resonance spectroscopy,high stability power supply
Mise en oeuvre des activités Enterprise Europe Network H2020 (KAM/EIMC) en Ile-de-France, en région Centre-Val de Loire, en région Normandie, en Nouvelle Calédonie et en Polynésie française. (TOPIC2INNO 2020-2021)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: France,France,France,France,France,France
Call: H2020 ENTREPRISE EUROPE NETWORK SGA4 2020-2021 (H2020-EEN-SGA4-2020-2021, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 907143.0
EU funding (EUR): 907143.0
Participants: 9
Project status: CLOSED

Implementation of the H2020 EEN activities in the geographical area covered by the the EEN TOPIC Consortium.

Keywords: h2020 een innovation europe companies
Mapping migration and adaptation in genomes (MAPGenome)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 148635.6
EU funding (EUR): 148635.6
Participants: 1
Project status: CLOSED

There is increasing evidence that gene flow between populations adapted to different environments is widespread in nature. Understanding this interplay of adaptation and migration at the genomic level is a fundamental goal of evolutionary biology, with wide applications in situations where these two forces operate, e.g. pesticide resistance or species invasion. Yet, this goal remains largely elusive, mainly because genetic signatures of local adaptation are confounded by other evolutionary processes, such as past demography, the removal of deleterious mutations and recombination. I will address this by integrating new computational methods with new data from experimental evolution and field populations. First, I will develop a method to map gene flow along the genome to find regions under divergent selection, taking the challenging step of modelling recombination and background selection. I will then apply it to characterize the spread of pesticide resistance in field populations of a major crop pest, Tetranychus urticae (spider mite). Due to their small genome (90Mb) and haplodidploidy, we have the unique opportunity to get phased genomes from haploid males. Third, by training-through-research, I will follow mites (and their genomes) evolving under controlled selection regimes in the laboratory (with vs without pesticide), varying migration rates. Combining my background on population genomics with the PI’s knowledge in spider-mite evolutionary ecology and the excellent conditions for experimental evolution at the host institute, we will move the field towards a comprehensive characterization of the genomics of adaptation in face of gene flow. The new method will be of general application to address fundamental questions on speciation and ecology, while providing a transferable framework to tackle societal challenges, from agriculture to human health and global change (e.g. find genes responsible for human disease and crop response to increasing temperatures).

Keywords: pesticide resistance,tetranychus urticae,molecular ecology,inference of demographic history,adaptation,gene flow
Integrated Services for Infectious Disease Outbreak Research (ISIDORe)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Other destinations
Action type: Research and Innovation actions
Countries involved: Belgium,France,United Kingdom,Finland,Germany,Netherlands,Austria,Sweden,Portugal,Hungary,Slovenia,Slovakia,Switzerland,Italy,Poland,Denmark,Latvia,Czechia,Norway,Greece,Ireland,Spain,New Caledonia,Serbia,Senegal,Mali,Burkina Faso,South Africa,Bangladesh,Israel,Bulgaria
Call: Research infrastructure services for rapid research responses to COVID-19 and other infectious disease epidemics (HORIZON-INFRA-2021-EMERGENCY-02, 2021)
Start date: 2022-02-01
End date: 2025-07-31
Duration (months): 42.0
Total project cost (EUR): 20998624.0
EU funding (EUR): 20998624.0
Participants: 162
Project status: SIGNED

The ISIDORe consortium, made of the capacities of European ESFRI infrastructures and coordinated networks, proposes to assemble the largest and most diverse research and service providing instrument to study infectious diseases in Europe, from structural biology to clinical trials. Giving scientists access to the whole extent of our state of the art facilities, cutting edge services, advanced equipment and expertise, in an integrated way and with a common goal, will enable or accelerate the generation of new knowledge and intervention tools to ultimately help control SARS CoV 2 in particular, and epidemic prone pathogens in general, while avoiding fragmentation and duplication among European initiatives. Such a global and interdisciplinary approach is meant to allow the implementation of user projects that are larger, more ambitious and more impactful than the EU supported transnational activities that the consortium is used to run. Our proposition is ambitious but achievable in a timely fashion due to the relevance and previous experience of the partners that we have gathered and that have complementary fields of expertise, which addresses the need for an interdisciplinary effort. Leveraging all these existing strengths to develop synergies will create an additional value and enhance Europe capacity for controlling emerging or re emerging and epidemic infectious diseases, starting with the COVID 19 pandemic. Such a global and coordinated approach is consistent with the recommendations of the One Health concept and necessary to make significant contributions to solving complex societal problems like epidemics and pandemics.

Keywords: responsiveness,preparedness,epidemic prone pathogens
Delivery of Small RNAs by Functional Hydrogel Nanoparticles to Improve Osmotic strEss Tolerance in Plants (DAFNE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy,Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-01
End date: 2025-09-30
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 2
Project status: CLOSED

RNA interference is a potent technology largely employed to trigger gene silencing and control specific biological processes. The delivery of small RNA is one of the most intriguing challenges in RNAi technology. Smart nanomaterials for safe and effective RNA delivery have been successfully exploited in animals, while a limited number of applications have been proposed in plants so far. The present project aims to develop and to validate smart hydrogel for small RNA (siRNA and miRNA) delivery able to knock down the expression of selected genes and ultimately promote osmotic stress tolerance in plants. To achieve these objectives, natural hydrogels such as dextran, poly(ethylene glycol), chitosan and alginate will be synthesised and functionalised with small RNAs in order to obtain nanomaterials with unique properties. Hydrogels will be applied to plant leaves and roots, both in vitro and in vivo. As proof of concept, DAFNE will target control genes such as phytoene desaturase (PDS) and green fluorescent protein (GFP) in the model species Arabidopis thaliana, whose knockdown phenotypes are well-known and easily detected. Subsequently, functional hydrogels will deliver stress-related miRNAs in order to develop drought tolerant plants in A. thaliana and in a representative food crop Solanum tuberosum. Merging distinct expertise, DAFNE will offer the candidate researcher multidisciplinary training in the field of plant biology and genetics, as well as in molecular and cell biology, which will expand her skills, currently based on chemical engineering.

Keywords: rnai,plant genetics,climate changes
NGI0 Review (NGI0 Review)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: A human-centred and ethical development of digital and industrial technologies
Action type: Coordination and support actions
Countries involved: Netherlands,Spain,Germany,Ireland
Call: NGI Tech Review (CSA) (HORIZON-CL4-2021-HUMAN-01, 2021)
Start date: 2022-08-01
End date: 2026-07-31
Duration (months): 48.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 9
Project status: SIGNED

NGI0 Review is a unique technical review and support hub for the Next Generation Internet initiative. Open source projects funded by NGI can apply for concrete technical assessments, audits and scans by experts in an open, collaborative environment. NGI0 Review levers the proven successful NGI Zero 'greenhouse environment' where selected open source projects are supported by world class domain experts in various fields such as security, accessibility, license compliance, standardization, internationalisation, etcetera. The experts participating in NGI0 Review provide reviews, guidance and mentoring so selected NGI projects can meet important requirements and needs of internet scale. Using a hybrid model of paid professional services and volunteer activity, the open collaborative environment allows anyone to contribute, including our extensive network of open source developers, data scientists, cybersecurity experts, standards experts, user interface designers and many more. Organized outreach and ecosystem engagement through ICT inclusivity experts like the Association for Progressive Communication and the oldest European internet charity NLnet foundation will disseminate the output of NGI0 Review to civil society, human rights and consumer organisations as well as mainstream media and educational environments. Finally, technology of selected projects can become part of the largest open source software collection currently available through the Nix community which packages software to be reproducible, reliable and verifiable.

Keywords: technical assessment,review,open source software