Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Development of a mobile device for the quick on-site measurement of soil nutrients (MobiLab)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: SME instrument
Countries involved: Austria
Call: Stimulating the innovation potential of SMEs for sustainable and competitive agriculture, forestry, agri-food and bio-based sectors (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2017-06-01
End date: 2020-02-29
Duration (months): 33.0
Total project cost (EUR): 1302812.5
EU funding (EUR): 911968.75
Participants: 1
Project status: CLOSED

Today the application of fertilisers to agricultural crops is mainly based on calculations, estimations and recommendations and not on analyses of the actual demand of soil and plants. The resulting over-fertilisation has substantial disadvantages: Farmers suffer from reduced yields and unnecessary expenses for fertilisers, groundwater is polluted, surface water bodies are eutrophicated, greenhouse gas is emitted from soils and finite natural fertiliser resources are depleted. It is estimated that up to 35 % of the applied fertiliser could be saved if a method for the quick and simple determination of the fertiliser demand existed. Pessl GmbH, an Austrian SME specialised in the development of innovative products in the field of agricultural monitoring and precision farming, has developed MobiLab, a lab-on-a-chip sensor for the quick on-site determination of the concentrations of the most important plant nutrients (ammonia, nitrate, phosphate and potassium) in the soil, based on the outcomes of the award-winning EU project OPTIFERT. MobiLab will enable farmers to determine the fertiliser requirements of their fields within just a few minutes and without the need for any special knowledge. The proper functioning and the great potentials of the technology have been proven, but further technological developments as well as the finalisation of a commercialisation concept are necessary to achieve the market breakthrough. Based on the outcomes of phase 1 of the project, all necessary steps for a successful market introduction of the MobiLab system will be taken. The MobiLab nutrient sensor will help European farmers to save up to 35 % of their applied fertiliser, leading to total potential annual savings of up to 6 billion € on the EU level. At the same time, Pessl Instruments GmbH will be able to significantly grow in terms of turnover, profit and employees and to further expand its leading position on the world market for precision farming products.

Keywords: fertilisation,precision farming,lab on a chip
Sulfur-Aluminium Battery with Advanced Polymeric Gel Electrolytes (SALBAGE)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Austria,Spain,Denmark,United Kingdom,United Kingdom,United Kingdom
Call: FET-Open research and innovation actions (H2020-FETOPEN-1-2016-2017, 2017)
Start date: 2017-11-01
End date: 2021-04-30
Duration (months): 42.0
Total project cost (EUR): 2998130.0
EU funding (EUR): 2998130.0
Participants: 7
Project status: CLOSED

Sulfur-Aluminium Battery with Advanced Polymeric Gel Electrolytes (SALBAGE) In SALBAGE Project, a new secondary Aluminium Sulfur Battery will be developed. The focus will be put in the synthesis of solid-like electrolytes based on polymerizable ionic liquids and Deep Eutectic Solvents in order to obtain polymer-gel electrolytes with an overall ionic conductivity in the range of 1-10 mS/cm at room temperature. At the same time, the aluminium negative electrode will be combined with a sulfur positive electrode including the unprecedented use of redox mediators, to facilitate sulfur reaction kinetics and boost performance. The new battery is expected to have a high energy density (1000Wh/kg) and low price compared with the actual Li-ion technology (-60%). Moreover, we will take advantage of the special features of the resulting battery (flexibility, adaptability, shapeability) to design a new device with the focus put on strategic applications such as transport, aircraft industry or ITs, for which the SALBAGE battery will be specially designed and tested in relevant conditions. To achieve the objectives a strong consortium has been gathered, with reputed experts in all the relevant fields, such as development of ILs and DES (University of Leicester, and Scionix Ltd.), polymerization (ICTP- CSIC), synthesis and characterization of materials for aluminium anode (TU Graz) and sulfur-cathode (Univ. of Southampton) and computational modelling (TU Denmark). This consortium is leaded by a European SME’s, Albufera Energy Storage, expert in the development and testing of batteries, with great interest in the future market exploitation.

Keywords: battery,sulfur,aluminium,sulphur,aluminum,energy storage,ionic liquids,polymer electrolyte,solid electrolyte,deep eutectic solvent,flexible shapeable battery,redox mediators
Innovative Stirring Blade Technology to increase profitability in the industry of algae culture based on CFD techniques (SBTech) (SBTech)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Microalgae have gained recent attention as sustainable and valuable inputs in many industries: biodiesel, human food, feed, pharmaceutical industry, cosmetics. Paradoxically, European microalgae production is not catching up with this growth, and USA and China are the global leaders. This negative trade balance implies that various European industries depend on international algae suppliers. Current prevailing technique for algae cultivation are the open raceways (RW) ponds, which still present a high improvement potential to improve their productivity, and hence thire profitability. Technological advances are needed to attract new entrepreneurs to this emerging industry. Our SBTech project aims at improving the RW system by applying a solution based on Computational Fluid Dynamics (CFD) technology, which will decrease energy consumption while increasing algae growth rate. Our solution reduces the production cost per kg of dried algae by 40%. At this cost level, microalgae become a promising raw material for many industries. In a second stage, SBTech will also be applicable to Photobioreactors, the second cultivation technique in importance. In Europe, algae industry is concentrated on a large number of small producers. Due to the rapid growth (7%) in three years there will be over 200 farms in Europe, mainly located in France, Netherlands, Portugal and Spain. However, forecasts are more optimistic, if we also consider the forthcoming boosting of microalgae for wastewater treatment (WWT): thousands of small WWT plants will be built to comply with current regulations. Our target customers are promoters/constructors of microalgae farms and algae-related industrial equipment manufacturers. There are not large international competitors in Europe, only local companies, and our system largely overcomes the alternative solutions. Based on our preliminary data, by the 3rd year from market launch, cumulative turnover will reach €11.33M, with a cumulative profit of €4.24M.

Keywords: microalgae,microalgae culture,wastewater treatment,mixing,fluid mechanics,numerical,simulations,open pond,raceway,agitation,blade,propeller,paddle wheel,energy efficiency
Self-disinfecting Photodynamic Catheters to Prevent Nosocomial Infections (PHOTOCATH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: CLOSED

Catheter-associated urinary infections (CAUTIs) are among the most common nosocomial infections, leading to substantial morbidity and mortality. They prolong hospital stays and significantly increase the economic cost of the disease. Despite the many techniques that have been developed to prevent them, spanning from the training of health professionals to the intraluminal use of antibiotics or "classical" microbicide coatings, the problem is still largely unsolved. A smart strategy to address the problem would be the development of a universal microbicide coating that only exercises its effect on the indwelling catheter when activated with visible light travelling through the catheter itself, the latter playing as a hollow optical fibre if made of transparent polymer. In this context, we aim to prepare self-disinfecting photoactive (urinary) catheters using the advanced components that modern chemistry and technology provide us, namely, (i) low-power super-bright cheap LEDs and laser diodes, (ii) highly transparent biocompatible polymers (silicones), (iii) versatile surface functionalisation techniques (plasma, silanisation) and (iv) tailored photosensitising dyes capable of generating large amounts of singlet oxygen upon illumination. This reactive oxygen species leads to the destruction of the microorganisms and, therefore, the incipient biofilm (antimicrobial photodynamic inactivation, aPDI), leaving unharmed any cell not contacting the catheter. The combination of the researcher knowledge (photochemistry, dye derivatisation and photodynamic effect), and some of the strongest areas of expertise within the host groups and collaborators (applied photonics, silicones and microbiology), provides all the necessary tools to tackle this challenging interdisciplinary proposal. The project success will benefit both the researchers involved and the entire society, as it contributes to overcome the problem of CAUTIs occurring in hospitals and long-term care facilities.

Keywords: photochemistry,singlet oxygen,photosensitiser dyes,photodynamic effect,catheter,microorganisms inactivation,disinfection,silicone
Maternal immune response to allogeneic embryos (Alloem)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-07-01
End date: 2022-06-30
Duration (months): 24.0
Total project cost (EUR): 191852.16
EU funding (EUR): 191852.16
Participants: 1
Project status: CLOSED

High embryonic mortality at the peri-implantation period (70%) is accounted after pig embryo transfer (ET), which is almost double than that of natural breeding or artificial insemination (AI). Since pregnancy is an interesting immunological paradox, our starting hypothesis is that the mechanisms regulating the maternal immune response to the embryos may be less efficient in the case of ET pregnancies, where the transferred embryos are allogeneic (e.g. contain paternal and maternal material unrelated to the recipient mother) than after natural breeding or AI, where only paternal material is unrelated to the mother (semi-allogeneic). This difference could be behind the increased embryonic death. The project will study transcriptomic and cytokine changes of porcine endometrial tissue in the presence of semi-allogeneic and allogeneic embryos during the peri-implantation period and also in the placenta of healthy and arrested fetuses. The results of the project will unveil mechanisms behind embryo-maternal dialogue. This fact is relevant in view of the necessary implementation of emergent breeding technologies, as embryo transfer (ET), for supporting sustainability and competitiveness of the European pig sector. EU is currently second biggest pig producer in the world and the largest exporter of antibiotic- and residue-free pig products derived from animals raised on highest welfare standards and with the highest genetic value. The understanding of embryo-maternal dialogue under allogeneic environments might be determinant to implement new strategies to increase the reproductive performance after ET not only in pigs but also, comparatively, in other livestock species and even in humans, where the use of donor oocytes for IVF is currently increasing. This project, with a focus on pregnancy immunological regulation, is of utmost interest for the EU goals, contributing to determine which factors still jeopardize full fertility and prolificacy when applying ET technology.

Keywords: embryo transfer,porcine,cytokines,gene expression,endometriun,pregnancy
Immune modulation by lymph node stromal cell-derived extracellular vesicles (IMSTREV)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-07-01
End date: 2017-06-30
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

Regulatory T cells (Tregs) are essential for maintenance of immune homeostasis and peripheral tolerance. The unique challenge to discriminate between pathogens and commensals requires the dynamic adaptation of Tregs to the microenvironment, particularly in the intestinal mucosa. Accordingly, although Tregs are primarily generated in the thymus, they can be also generated in the periphery, and gut-draining mesenteric lymph nodes (mLN) were shown to display a higher Treg-inducing capacity compared to skin-draining peripheral LNs (pLN). Our previous data suggest that these site-specific functional differences of LNs can be attributed to fibroblastic reticular stromal cells (FRCs), and the high Treg-inducing capacity of mLN can be imprinted in LN stromal cells by commensal microbiota. To decipher the molecular details of these site-specific immune-modulatory differences we generated immortalized FRCs, and preliminary data suggest that soluble factors secreted by mLN-derived FRCs mediate the high Treg-inducing capacity of mLN. The present proposal aims to identify molecules secreted from mLN-FRCs that modulate the differentiation of naïve T cells into Tregs. Special emphasis will be laid on the novel field of intercellular communication by extracellular vesicles (EVs), and both RNA-Seq and mass spectrometry approaches will be applied to identify the critical factors on a molecular level. To formally proof the functional importance of the newly identified candidate molecules, immortalized FRCs will be genome-edited using CRISPR-Cas9 technology and tested for their Treg-inducing capacity. Gaining insight into the cellular-subcellular interactions and major molecular mechanisms of peripheral tolerance and Treg generation anticipates promising tools for future vaccine development and therapeutic applications to treat chronic inflammatory and autoimmune diseases.

Keywords: fibroblastic reticular cells,extracellular vesicles,tolerance,lymph node,regulatory t cells
Polarity and Central-Symmetry in Asymptotic Geometric Analysis (PolSymAGA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Israel
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-09-01
End date: 2024-08-31
Duration (months): 72.0
Total project cost (EUR): 1514125.0
EU funding (EUR): 1514125.0
Participants: 1
Project status: SIGNED

Asymptotic Geometric Analysis is a relatively new field, the young finite dimensional cousin of Banach Space theory, functional analysis and classical convexity. It concerns the {\em geometric} study of high, but finite, dimensional objects, where the disorder of many parameters and many dimensions is ``regularized'' by convexity assumptions. The proposed research is composed of several connected innovative studies in the frontier of Asymptotic Geometric Analysis, pertaining to the deeper understanding of two fundamental notions: Polarity and Central-Symmetry. While the main drive comes from Asymptotic Convex Geometry, the applications extend throughout many mathematical fields from analysis, probability and symplectic geometry to combinatorics and computer science. The project will concern: The polarity map for functions, functional covering numbers, measures of Symmetry, Godbersen's conjecture, Mahler's conjecture, Minkowski billiard dynamics and caustics. My research objectives are twofold. First, to progress towards a solution of the open research questions described in the proposal, which I consider to be pivotal in the field, including Mahler's conjecture, Viterbo's conjecture and Godberesen's conjecture. Some of these questions have already been studied intensively, and the solution is yet to found; progress toward solving them would be of high significance. Secondly, as the studies in this proposal lie at the meeting point of several mathematical fields, and use Asymptotic Geometric Analysis in order to address major questions in other fields, such as Symplectic Geometry and Optimal transport theory, my second goal is to deepen these connections, creating a powerful framework that will lead to a deeper understanding, and the formulation, and resolution, of interesting questions currently unattainable.

Keywords: convex geometry,asymptotic geometric analysis,convex billiards,covering numbers,mahler conjecture,asymmetry measures
Environmental Urban Monitoring System (EnvironmetrY)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Italy
Call: Boosting the potential of small businesses in the areas of climate action, environment, resource efficiency and raw materials (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-02-01
End date: 2018-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Environmental monitoring serves a vital industrial and scientific role by revealing long-term trends, leading to new knowledge and understanding; monitoring is also essential for evaluating environmental planning and policy since without monitoring, they cannot prove their success or identify areas for improvement. Monitoring activities have acquired an increased relevance also when considering the Industry 4.0 paradigm. W2W intends to introduce in the market Environ&metrY, as an integrated, homogeneous, scalable and modular air and environmental monitoring system, for urban and sub-urban areas, deployed through a scalable cloud-based platform for the IoT, developed and owned by the applicant, COIOTE (www.coiote.io), and the new technology for wireless data transmission SigFox, LoRaWAN GPRS as well as NB-IoT or and indoor environments, on the basis of specific users requirements. The innovation is meant to be used in outdoor contexts, but providing also an indoor applicability, since it can be used within close public space environments, such as school, offices, universities, banks, etc. The aim of the project is to develop a complete feasibility study so for: Business strategy definition and validation; defining market issues; setting technological and organization requirements; developing a multiannual financial overview; defining IPR related issues.

Keywords: monitoring,environment,pollution,industry 4 0,compliance
European Market for Climate Services (EU-MACS)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Fighting and adapting to climate change
Action type: Research and Innovation actions
Countries involved: Germany,Austria,Germany,Italy,Italy,Belgium,Finland,Netherlands,United Kingdom
Call: Climate services market research (H2020-SC5-2016-OneStageB, 2016)
Start date: 2016-11-01
End date: 2018-12-31
Duration (months): 26.0
Total project cost (EUR): 1499621.25
EU funding (EUR): 1499621.25
Participants: 9
Project status: CLOSED

The project analyses the market structures and drivers, obstacles and opportunities from scientific, technical, legal, ethical, governance and socioeconomic vantage points. The analysis is grounded in economic and political science theories on how service markets with public and private features can develop, and how innovations may succeed. The consortium offers a good cross-section of representation from various vantage points in the climate services market, complemented by expert knowledge on market research and innovation policy. The consortium has excellent connections to many climate service user types and other stakeholders. The study will engage a large diversity of stakeholders in many ways, especially through the explorative market development exercises employing different co-design approaches. Next to reporting based analysis of market functioning and solutions, the protocols developed in the explorative market development exercises are meant for replication at large scale.

Keywords: matching supply and demand,innovation uptake,removing barriers,market failures,awareness raising,collaborative market development,living labs,climate services value chain