Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Near Earth Object Modelling and Payloads for Protection (NEO-MAPP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling European competitiveness, non-dependence and innovation of the European space sector
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Germany,Germany,Germany,Spain,Switzerland,Greece,Belgium,France,France,France,Luxembourg,Portugal
Call: Advanced research in Near Earth Objects (NEOs) and new payload technologies for planetary defence (H2020-SPACE-2019, 2019)
Start date: 2020-02-01
End date: 2023-05-31
Duration (months): 40.0
Total project cost (EUR): 3998591.5
EU funding (EUR): 3998591.0
Participants: 17
Project status: SIGNED

Planetary defence, science or resource missions to asteroids require new advances in numerical modelling, payload development, data processing technology, and operational capabilities. The NEO-MAPP consortium includes scientific and industrial experts with a solid expertise in asteroid science and space missions and is, therefore, ideally placed to further advance NEO scientific research and technologies. In a multi-disciplinary and synergetic approach, NEO-MAPP incorporates two activities: numerical modelling, and technology and data processing developments. NEO-MAPP will bring modelling capabilities well beyond the state-of-the-art, producing major advancements in our understanding of the response of NEOs to a kinetic impact or an Earth encounter, and of their physical and dynamical properties. NEO-MAPP will also increase the maturity of five innovative payloads specifically optimized for NEO space missions and devoted to the surface, sub-surface and internal properties of a NEO; parameters that are currently poorly constrained yet of high importance to planetary defence. In parallel, the NEO-MAPP team will define innovative measurement and data processing strategies, combining multiple payloads, in order to maximize the exploitation of scientific and technical data. These objectives will be addressed by adopting a framework of two “Reference Missions”. The team will ensure that the mission scenarios are both highly relevant to the current international and European programmatic context while remaining generic enough to be transposable to any alternative scenarios. NEO-MAPP will thus provide significant advances in our understanding of NEOs while ensuring the future leadership of European scientists and engineers in both planetary defence and small-body exploration. The project outcome, especially regarding impact mitigation (but also asteroid mining), responds to a public demand and, therefore, will have a high social and environmental impact.

Keywords: asteroids,planetary defence,kinetic impactor,near earth objects,numerical modelling,payload development,data processing
A unique cost-effective and point of care (PoC) kit for the non-invasive rapid in vitro diagnosis of meningococcal disease (MeningoSpeed)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-03-01
End date: 2019-06-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Meningococcal disease (MD), caused by Neisseria meningitidis serogroups (mainly ABCXWY), annually affects 1.2 million people worldwide (mainly children and young). Due to its high lethality (8-15% treated patients), permanent sequelae and epidemic potential, MD represents a major public health problem. Despite the societal burden, there is a lack of rapid and accurate diagnostic tools for timely and early treatment that results very costly for healthcare systems (e.g. direct costs valued in € 68 m/hospital/year). In response to the unmet need, BioSpeedia (spin-off from the Institute Pasteur, France) has vast experience in infectious diseases management and is developing the first-ever gold nanoparticle-based immunochromatographic test with demonstrated diagnostic capability for the six Nm serogroups. MeningoSpeed is a non-invasive, accurate (sensitivity and specificity >93%), rapid (<15 min vs PCR: 3h) and cost-competitive in vitro diagnostic test (€45 sample, at least 25 % cheaper than latex agglutination tests and PCR alternatives) for MD diagnosis. Our one-step solution will result on added value for patients, physicians and healthcare purchasers by improving disease monitoring in an accurate and timely fashion way, reducing deaths and sequelae. MeningoSpeed will provide healthcare systems with limited resources with a reliable and cost-effective diagnostic tool, leading to significant cost-savings. MeningoSpeed´s high accuracy and performance under a faster and cheaper cost make it a disruptive solution with great potential for commercial success in the growing point-of-care market (€33 B by 2022, CAGR 10%). Thus, MeningoSpeed is projected to be a profitable business opportunity and a core source of growth for the company (ca. €33 M of accumulated net profit during 2022-2026). A next feasibility study covering the technological, commercial and financial issues will enable us to finalize our business plan and secure our steps towards the successful market launch.

Keywords: bacterial meningitis,meningococos,neisseria meningiditis,in vitro diagnostic,rapid diagnostic test,saepticaemia
Strong single-photon radiation-pressure coupling for quantum optomechanics (STRONG-Q)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-03-01
End date: 2021-02-28
Duration (months): 60.0
Total project cost (EUR): 1499970.0
EU funding (EUR): 1499970.0
Participants: 1
Project status: CLOSED

While quantum physics is one of the most successful theories in modern science, it remains a puzzle why we do not observe quantum effects in our macroscopic every-day life. Quantum theory in fact does not pose an inherent limit on the size and mass of a quantum system. The field of optomechanics has been established with the explicit goal of testing massive, macroscopic quantum states. Here, the radiation-pressure force is used to bring a mechanical oscillator into a quantum state by coupling it to light. Most current experiments are however limited by either the optical or mechanical quality of the mechanical system, which so far have prevented a true breakthrough. I will use two-dimensional photonic crystals on silicon nitride membranes to build a new generation of optomechanical systems, consisting of arrays of mechanical oscillators with high reflectivity and unprecedented mechanical quality. This will allow me to finally enter the single-photon strong coupling (SPSC) regime. This regime, which to date is far beyond experimental reach of any state-of-the-art system, will open up the possibility of true quantum experiments involving macroscopic mechanical objects. Preliminary experiments reveal that we can fabricate membranes of unparalleled optical and mechanical quality necessary for realizing STRONG-Q. A fundamentally new approach combined with our novel devices will allow me to access the SPSC regime. I will be able to study superradiance, single-photon blockade and non-Gaussian states, explore avenues for phonon lasing, and perform quantum experiments that were up to now impossible. As enabling technologies I will build an entangled-photon source and highly efficient photodetectors. With my expertise in (single-photon) quantum optics and optomechanics, and with TU Delft’s infrastructure as a leading institute in quantum technologies and microfabrication, the ultimate goal of this project to bring quantum physics into the macroscopic world is within reach.

Keywords: optomechanics,strong coupling,photonics,macroscopic quantum states,single photons,decoherence,microfabrication,photonic crystals,foundations of quantum physics
Novel selective mTORC1 inhibitors (inhibiTOR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Switzerland
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Hepatocellular carcinoma (HCC) is the predominant form of liver cancer and the fourth leading cause of cancer-related deaths worldwide. The multikinase inhibitor sorafenib is the only approved drug to treat HCC and on average enhances survival by three months. Thus, the efficacy of current HCC treatment options is very limited. Studies in the context of our ERC-Synergy grant revealed that sorafenib resistance correlates with upregulation of mammalian target of rapamycin complex 1 (mTORC1) signaling. The central role of mTORC1 in conferring therapy resistance suggests that effective therapy against HCC may require combination of a primary inhibitor (e.g., sorafenib) and an mTORC1 inhibitor. The mTORC1 inhibitor rapamycin and its derivatives (rapalogs) are approved for a few advanced cancers, but not for HCC. Their clinical applicability is limited by their effectiveness and safety. Rapalogs fail to completely inhibit mTORC1 as they have little effect on inhibiting phosphorylation of 4E-BP, one of the two main targets of mTORC1. Moreover, rapamycin and rapalogs also inhibit mTORC2 when chronically administered, leading to undesirable effects such as hyperglycemia, hyperlipidemia, and insulin resistance. We have established a biophysical assay to identify selective mTORC1 inhibitors with a novel, rapalog-unrelated, mechanism of action. We predict these inhibitors to be more selective, more effective, and potentially safer than mTORC1 inhibitors currently used in the clinic. In this Proof of Concept project, we aim to study the pharmacological potential of selective and efficient mTORC1 inhibition alone or in combination therapy with sorafenib to treat HCC.

Keywords: mtor signaling,hepatocellular carcinoma,mtorc1 inhibition,drug development,biophysical screening
Statistical modeling for Optimization Mobility (SOM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-10-01
End date: 2018-03-31
Duration (months): 18.0
Total project cost (EUR): 149109.0
EU funding (EUR): 149109.0
Participants: 1
Project status: CLOSED

This project will commercialize software and internet services for improving mobility-related online services such a ride sharing, navigation systems and crowdsourcing. In particular, we will commercialize an app for mobile devices which makes predictions on the future travel intentions of the user based on the rich data available on the device through the use of highly efficient predictive modeling techniques. Based on these predictions, the mobile device can communicate in the background on ride sharing, crowdsourcing and congestion avoidance. Three key competitive advantages are (1) the privacy one gets in contrast with most cloud-based platforms where all data is centrally collected, (2) the saving of computational costs by distributing computations to devices having much more detailed information than what one can centrally collect, and (3) the fact that most services work with current traffic information, while we work with future travel intentions, allowing for planning better ahead. The commercialization of this technology will be realized by improving the existing network of potential industrial partners and end-users, demonstrating the technology for key services, exploring alternative commercialization strategies, and preparing a team to carry on the exploitation. When successful, this project will have lead to significant economic and societal benefits in improving the efficiency of crowdsourcing and ride sharing, increasing the popularity of ride sharing and reducing congestions.

Keywords: data mining,machine learning,mobility,mobile device computing,ride sharing,crowdsourcing
Drone Critical Communications (DroC2om)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Germany,France,Denmark,Denmark
Call: Datalink (H2020-SESAR-2016-1, 2016)
Start date: 2017-09-01
End date: 2019-08-31
Duration (months): 24.0
Total project cost (EUR): 1270542.5
EU funding (EUR): 1270542.5
Participants: 4
Project status: CLOSED

The key objective of the DroC2om project is to contribute to the definition of integrated cellular-satellite data link specifications for UASs. Major focus will be on the design and evaluation of data links based on experimental radio investigations and system simulations. The primary goal is to design a cellular-satellite system architecture concept, which ensures reliable and safe operation for remote controlled, semi-autonomous and fully autonomous small UAS. The DroC2om project will design and evaluate an integrated cellular-satellite system architecture concept for data links in order to support reliable and safe operation of UAS based on real drone measurements and modelling. The diversity of the project partners ensures a balanced and high quality expertise in all relevant technological areas. • Thales Alenia Space is a key player in aerospace air/ground communications. • Nokia is one of the major mobile service and infrastructure providers worldwide. • atesio provides solutions for automatic planning and optimization algorithms of multi-layer multi-service cellular telecommunication networks. • Aalborg University has a well-established research centre for mobile communications systems. To meet its objectives, the approach of DroC2om is to structure the work around four main building blocks that will be communicating with each other along the execution of the project following a continuous delivery approach: 1. Definition of scenarios and requirements 2. Software-based evaluation environment for aerial drone communication 3. Aerial communication system architecture 4. Drone flight and measurements All these four building blocks will be structured by a tight and rigorous management action from the project manager (PM) and the technical manager (TM), and complemented with a particular action devoted to ensure the proper dissemination of all activities, results, and outcomes of the project to maximize impact and visibility of the actions carried out.

Keywords: drone data link,reliability,cellular networks
SEcure Network Coding for Reduced Energy nexT generation Mobile Small cells (SECRET)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Germany,Greece,Finland,United Kingdom,Portugal,United Kingdom,Portugal
Call: Innovative Training Networks (H2020-MSCA-ITN-2016, 2016)
Start date: 2017-01-01
End date: 2020-12-31
Duration (months): 48.0
Total project cost (EUR): 3274857.72
EU funding (EUR): 3274857.7199999997
Participants: 8
Project status: CLOSED

SECRET is a collaborative European Training Network (ETN) committed to create an “excellent” educational training platform; that is multi-disciplinary and intersectoral in nature, for Early Stage Researchers (ESRs) in the field of wireless communications and networking. In this dynamic field, the challenges are always evolving and more stringent in line with market expectation, and socio-economical requirements. The chapter of 4G (4th Generation) of mobile systems is finally coming to an end, with waves of 4G systems deployed over Europe and worldwide. 4G systems provide a universal platform for broadband mobile services at any time, any place and anywhere. However, mobile traffic is still growing at an unprecedented rate and the need for more sophisticated broadband services is still further pushing the limits on current standards to provide even tighter integration between wireless technologies and higher speeds. The increase in number of mobile devices and traffic, the change in the nature of service and device, along with the pressure on operation and capital costs, and energy efficiency are all continuously putting stringent limits on the requirement of the design of mobile networks. It is widely accepted that incremental enhancements of current networking paradigm will not achieve or come close to meeting the requirements of networking by 2020 . This has led to the need of a new generation of mobile communications: the so-called 5G. The interests of stakeholders and academic researchers are now focused on 5G paradigm. Although 5G systems are not expected to penetrate the market till 2020, the evolution towards 5G is widely accepted to be the convergence of internet services with existing mobile networking standards leading to the commonly used term “mobile internet” over heterogeneous networks (HetNets), with very high connectivity speeds. This proposal aims to narrow the gap between current networking technologies and the foreseen requirements of future 2

Keywords: mobile small cells,cooperation,network coding,antennas,power amplifiers,femto,security
Certification of quantum technologies (CERQUTE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Spain
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 1735043.75
EU funding (EUR): 1735043.75
Participants: 1
Project status: SIGNED

Given a quantum system, how can one ensure that it (i) is entangled? (ii) random? (iii) secure? (iv) performs a computation correctly? The concept of quantum certification embraces all these questions and CERQUTE’s main goal is to provide the tools to achieve such certification. The need of a new paradigm for quantum certification has emerged as a consequence of the impressive advances on the control of quantum systems. On the one hand, complex many-body quantum systems are prepared in many labs worldwide. On the other hand, quantum information technologies are making the transition to real applications. Quantum certification is a highly transversal concept that covers a broad range of scenarios –from many-body systems to protocols employing few devices– and questions –from theoretical results and experimental demonstrations to commercial products–. CERQUTE is organized along three research lines that reflect this broadness and inter-disciplinary character: (A) many-body quantum systems: the objective is to provide the tools to identify quantum properties of many-body quantum systems; (B) quantum networks: the objective is to characterize networks in the quantum regime; (C) quantum cryptographic protocols: the objective is to construct cryptography protocols offering certified security. Crucial to achieve these objectives is the development of radically new methods to deal with quantum systems in an efficient way. Expected outcomes are: (i) new methods to detect quantum phenomena in the many-body regime, (ii) new protocols to benchmark quantum simulators and annealers, (iii) first methods to characterize quantum causality, (iv) new protocols exploiting simple network geometries (v) experimentally-friendly cryptographic protocols offering certified security. CERQUTE goes at the heart of the fundamental question of what distinguishes quantum from classical physics and will provide the concepts and protocols for the certification of quantum phenomena and technologies.

Keywords: quantum information theory,many body physics,quantum foundations,quantum certification,entanglement,bell s theorem,quantum cryptography,quantum networks,randomness,numerical algorithms
Women Leaving Religion in the UK and the Netherlands (WOMENEXREL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-11-01
End date: 2024-03-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

Women are often thought to be more religious then men. At the same time, a number of women disaffiliate from their religious tradition and/or community. This research explores the lived realities of women from Jewish, Christian and Islamic religious backgrounds in the UK and the Netherlands, who self-identify as having left religion. It is expected that different former faiths, the community one belongs/belonged to, and aspects such as age, education and sexuality all inform women’s experiences of leaving religion. This project will contextualise these women’s trajectories in relation to the different religious and secular dynamics and circumstantial differences of the UK and the Netherlands. Using a new and innovative life history approach , the project contributes to the study of non-religion and leaving religion, the interdisciplinary study of religion and gender, and the empirical comparative study of Judaism, Christianity and Islam. Bringing women of different religious backgrounds (Judaism, Christianity and Islam) together in the same research will lead to new and original insights into the dynamics of current Western European secularising and diversifying societies. This research will investigate: a) how and why women leave their Jewish, Christian or Islamic faith and/or community; b) how aspects such as gender, generation, education, sexuality and race/ethnicity contribute to women’s experience of leaving religion; c) and their post-exit relations with family and community. This project combines a life history approach with participant observation at events organised by and for formerly religiously observant individuals, as well as interviews with organisers, activists and therapists dealing with formerly observant women. The results will be used to theoretically rethink the connections between (non-)religion, leaving religion, gender and race/ethnicity.

Keywords: women,non religion,leaving religion,life history,the united kingdom,the netherlands,judaism,christianity,islam,comparative analysis