Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Enantioselectivity at surfaces: covalent grafting as new tool for chiral surface modifications (EnSurf)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 160800.0
EU funding (EUR): 160800.0
Participants: 1
Project status: CLOSED

Chiral surfaces have received considerable attention in the recent past since they play an important role as substrates for chiral separations and enantioselective heterogeneous catalysis. One of the most frequently used approaches to design and fabricate chiral surfaces is the adsorption and self-assembly of chiral or prochiral molecules on surfaces, which can be studied with sub-molecular resolution by scanning tunneling microscopy (STM). Thereby, the fabrication of homochiral surfaces is of particular interest. However, a major drawback of this approach is, in particular in view of potential applications, the lack of stability of physisorbed molecules. Therefore, EnSurf aims to use covalent surface modifications as chiral surface modifiers and new experimental approach for the creation of homochirality and enantioselectivity in self-assembling molecular structures at the solid/liquid interface. This interdisciplinary project takes place in the field of surface and interface science and involves aspects of supramolecular chemistry, synthetic chemistry, analytical chemistry and theoretical chemistry. Ultimately, this project will allow the fellow to attain professional independence and a position at the frontier of future academic or industrial research by a combination of hands-on experience in diverse research areas and training in complementary skills.

Keywords: chirality,scanning probe microscopy,enantioselectivity
City Campus meets Illuminale 2016 / 2017 (Brainwaves)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Germany
Call: European Researchers' Night (H2020-MSCA-NIGHT-2016, 2016)
Start date: 2016-04-01
End date: 2017-11-30
Duration (months): 20.0
Total project cost (EUR): 386750.0
EU funding (EUR): 171000.0
Participants: 1
Project status: CLOSED

With the slogan “Brainwaves” the Researchers’ Night in Trier – City Campus meets Illuminale– will be showing that science is for everyone. There is a researcher in all of us. You only need a clever mind and a lot of curiosity. Our aim is to organize a public event showing on the one hand the exciting, interesting side of science and on the other hand how science can improve the citizens' everyday life. Another main target is to enhance public recognition of researchers and their role in society. Practical results of research will be delivered in a comprehensive and illustrative form, showing that science is all around us. To simulate everyday life situations the City Campus is grouped into seven Science Sceneries in the heart of the City. In these Sceneries different research presentation formats will be organized, using new formats of knowledge transfer. To bring science and researchers into peoples’ everyday life, the Sceneries will take place in unusual settings representing peoples’ normal life, e.g. the Science market place with Stage and European Corner, the Scientific Theatre and the area “Science goes to school”. The City Campus program includes hands on experiments and demonstrations, shows, contests, quizzes, exhibitions and much more. A significant number of researchers will participate in public events to interact face-to-face with the public. The visitors – mobilized through an extensive awareness campaign – will be given the chance to touch, feel and smell science. To increase the attractiveness the effective event Illuminale will be integrated in the European Researchers’ Night. Artistic illuminations of buildings and places will be combined with interesting spotlights on several areas of research. These spotlights are a metaphor for science and knowledge. Partners are the Trier University of Applied Sciences, the ttm trier Tourismus & Marketing GmbH and the Municipality of Trier.

Keywords: researchers night,city campus,research,innovation,science sceneries,research career,knowledge transfer,experiment
Supporting the Promotion of Equality in Research and Academia (SUPERA)

Framework: Horizon 2020 — Science with and for Society
Programme: Promote gender equality in particular by supporting structural change in the organisation of research institutions and in the content and design of research activities
Action type: Coordination and support actions
Countries involved: Austria,Italy,Spain,Hungary,Belgium,France,Portugal
Call: Support to research organisations to implement gender equality plans (H2020-SwafS-2017-1, 2017)
Start date: 2018-06-01
End date: 2022-05-31
Duration (months): 48.0
Total project cost (EUR): 2029981.25
EU funding (EUR): 2029980.25
Participants: 10
Project status: CLOSED

The main aim of the SUPERA project is to implement 6 fully-fledged Gender Equality Plans to articulate a structural understanding of gender inequalities, stereotypes and biases in research as a cross-cutting issue to tackle in their complex, multi-layered dimensions and the inclusion of a gender perspective in research and academia, with a holistic set of measures addressing the above-mentioned objectives of the European Commission’s strategy: - Building gender sensitive career management and workplaces; -Transforming decision-making towards accountability, transparency and inclusiveness; and - achieving excellence through strengthening the gender dimension in research and knowledge transfer. Any devised solution to be operationalized through the GEPs should take into account contextual features to reach effectiveness, and that innovative measures or initiatives designed by SUPERA should be brought to the knowledge of relevant stakeholders to feed their own expertise regarding SUPERA’s key areas. Partners within SUPERA’s consortium reflect the ambition of this project: maintaining a dual approach, RPOs are characterized by their size and impact potential, and their multidisciplinarity and vast academic offer (UCM, UNICA, CEU, UC-CES), while RFOs (MINECO, RAS) from the same partner countries as UCM and UNICA, respectively, are integral in maximising outreach and comitment as relevant public entities on a national level. This fact, while adding a complexity layer to GEP implementation, expands the scope of the project and the potential long-term impacts regarding sustainability and institutionalisation. SUPERA will be designed based on four core principles that will tackle the main barriers of implementing GEPs in research organizations: cumulativeness; innovation; inclusiveness and sustainability.

Keywords: gender equality,institutional change,gender in research,research performing organisations,research funding organisations,gender equality plan
Advanced Load Sensing technology for Aerospace Application (TecALSens)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Germany
Call: Advanced Load Sensing technology for aerospace applications (H2020-CS2-CFP07-2017-02, 2017)
Start date: 2018-11-01
End date: 2021-10-31
Duration (months): 36.0
Total project cost (EUR): 865157.5
EU funding (EUR): 605610.25
Participants: 1
Project status: CLOSED

The objective of the TecALSens project is the provision of an advanced and validated load sensor for integration in the Smart Integrated Wind Demonstrator and validation in an industrially relevant environment. The project covers the whole process chain taking into consideration specific requirements: from designing of all sensor components through manufacturing of load cell, electronics and sensor body up to validation and verification of its properties and operational behavior. Electronics will be designed and manufactured considering DO-254 specifications; The complete systems will be tested according to DO-160 requirements. In TecALSens a two-step approach will be pursued. After manufacturing, the load sensor will be tested for TRL 4 and TRL 5 compliance. The design phase will support the experimental validation by taking into consideration the environmental conditions. On the basis of these results a critical review and improvement of all steps will be performed. The improved sensor will be tested again following the same procedures. The project will provide a robust and reliable solution based on innovative sensor principle for further application in primary, secondary flight controls and landing gear systems. With this solution their functional safety can be enhanced. An industrialization path will be defined and verified at each step for further production.

Keywords: load sensor,force measurement,strain gauge,electronic amplifier,industrialisation
Development of a bifunctional hierarchically structured zeolite based nano-catalyst using 3D-technology for direct conversion of methane into aromatic hydrocarbons via methane dehydroaromatization (ZEOCAT-3D)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Research and Innovation actions
Countries involved: Iran, Islamic Republic of,Spain,Austria,Spain,Spain,Spain,Greece,Belgium,Greece,Greece,France,France,France,France,Netherlands,Netherlands
Call: Catalytic transformation of hydrocarbons (RIA) (H2020-NMBP-ST-IND-2018, 2018)
Start date: 2019-04-01
End date: 2023-03-31
Duration (months): 48.0
Total project cost (EUR): 6764020.0
EU funding (EUR): 6764020.0
Participants: 21
Project status: SIGNED

The goal of the project ZEOCAT-3D is the development of a new bi-functional (two types of active centers) structured catalysts, achieving for the first time a tetramodal pore size distribution (micro-, meso1-, meso2-, macro-porous) and high dispersion of metal active sites for the conversion of methane, coming from different sources as natural gas and biogas, into high value chemicals such as aromatics (benzene, naphthalene, among others) via methane dehydroaromatization (MDA). The main drawbacks associated with this process are: Low methane conversion, low selectivity towards the desired products and the quickly deactivation due to carbon deposition onto catalyst. These problems will be overcome by the use of hierarchical zeolites structures synthetized by 3D-printing and loaded with doped molybdenum nano-oxides. The methodology of the project will go from laboratory to pilot scale demonstration in a real environment. Catalyst design and operation conditions will be optimized for different methane feedstock at lab-scale and then upscaling and construction of a final prototype will be carried out. The optimisation of these catalytic processes will bring enormous advantages for increasing the exploitation of natural gas and biogas, since ZEOCAT-3D is very well in accordance with the programme topic NMBP-24, regarding development industrial process to obtain high value chemicals at the same time that the dependence from the current fossil fuel is reduced.

Keywords: catalyst,zeolite,nano oxides,3d printing
Wireless Optogenetics to elucidate the function of corticostriatal neurons in biRDsong (WORD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-02-01
End date: 2024-04-30
Duration (months): 24.0
Total project cost (EUR): 191149.44
EU funding (EUR): 191149.44
Participants: 1
Project status: TERMINATED

Corticostriatal neurons are vital components of brain circuits that connect cortical areas to the striatum, and are known to play essential roles in the control of cognitive and motor functions. The contribution of these projection neurons in shaping vocal behaviors in the healthy brain and their implications in disease are nonetheless still not well understood. I will use songbirds as a model system to investigate the functional roles of a corticostriatal neuron population during the production of vocal sequences and in reinforcement learning of vocal features. Songbirds are the prime model system to study the neural basis of speech development and complex motor skill acquisition, due to the many parallels between birdsong and human speech and their respective neural correlates. I will investigate corticostriatal neurons in nucleus HVC (proper name), the songbird vocal premotor cortex analog. Neural activity in HVC has been thoroughly studied in the past, but the roles of individual HVC neuron types in mediating vocal sequences and the stereotypy and flexibility of song features remain poorly understood. I will be using optogenetics to manipulate activity in HVC’s corticostriatal neurons during the production of song sequences, and while birds are adapting song features in response to an externally applied aversive auditory stimulus. I will first develop novel tools to enable such investigations in songbirds, including new viral constructs to target specific projection neuron populations and wireless sensor nodes for performing vocal output-triggered optogenetic manipulations without movement restrictions for experimental animals. I will then apply the developed tools to conduct optogenetic manipulations of corticostriatal neurons in freely moving, vocalizing birds in social groups. These experiments will shine new light into the role of corticostriatal neurons in shaping complex vocal behaviors.

Keywords: corticostriatal neurons,optogenetics,birdsong,vocal learning,reinforcement learning,songbird,vocal behavior
Environmental changes and global recovery of primary producers after the Cretaceous/Paleogene boundary (KPgB): A molecular fossil approach (EPROAMA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-01
End date: 2023-12-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

The mass extinction marking the Cretaceous/Palaeogene boundary (KPgB), 66.02 million years ago. It was one of the most devastating events in the history of life, as well as the most recent and best studied of the ‘big five’ mass extinctions that occurred during the Phanerozoic. After decades of research, one of the most critical lines of inquiry is understanding the short- to long-term effects of this impact on the global environmental system, including the re-establishment of pre-impact environmental conditions and marine biological productivity. After characterizing how the recovery of palaeoenvironmental conditions were by the analysis of inorganic geochemical proxies, critical questions were raised about the nature of and recovery after the event. how did primary productivity and the biological pump change and how did that impact the source and character of organic matter reaching the seafloor? And crucially, how did these interlinked processes recover after the impact event? The Caravaca section is amongst the most continuous, well-preserved, and well-studied KPgB distal sections in the world. This allows these questions to be explored using molecular fossils (or biomarkers) – for the first time in this section and consequently at unprecedented stratigraphic resolution. The approach will broadly encompass several methods, all of which will be carried out in the OGU (Organic Geochemistry Unit) at Bristol University. These will include but are not limited to, the determination of total organic carbon (TOC) contents; the extract and analysis of the biomarkers from ground samples; the determination of key biomarker abundances and distributions by GC and GC-MS in order to ascertain changes in organic matter (OM) source, algal assemblages, terrestrial biomarkers, redox state (pristane/phytane ratio; homohopane index) and microbial inputs (hopanes); and finally, to explore changes in ‘apparent thermal maturity’ which could reflect changes in reoworked OM input.

Keywords: cretaceous,paleogene boundary,biomarkers,organic matter sources,phytoplankton community,paleoenvironmental reconstruction
The Politics of Cultural Exchange: Anna of Denmark and the Uses of European Identity (Mapping Anna)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-01-16
End date: 2019-01-15
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

"The Politics of Cultural Exchange: Anna of Denmark and the Uses of European Identity" investigates how cultural exchange operates across the confessional and geographic divides of pre-modern Europe through a transnational case study of Anna of Denmark (1574-1619), Queen of Scotland and England. This synoptic study combines her vernacular patronage with new evidence of her European connections manifested in her Latin diplomatic correspondence and her material artefacts and commissions. Analysis of new archival, visual, and material sources in Denmark, England, Scotland, and Sweden illuminates Anna’s networks and agendas. Her Latin correspondence offers insights into how she negotiated linguistic and political barriers; her commissions of artists, architects, garden designers, musicians, and scholars demonstrate her pan-European cultural connections. Reformulating theories of agency, analysing interactions between physical and intangible cultural artefacts, and examining the strategic use of 'national' labels as tools of political communication, this project raises academic and public awareness about women’s role in history, redefining how European culture spanned national borders. Located between the fields of material and visual history, theatre, and literary criticism, it reshapes interpretations of national identity, female agency, and spatial politics. Thus, it opens up neglected areas of European gender and culture histories, responding to concerns articulated by the ESF (among others) over sustaining the cultural literacy of the next generation. "Mapping Anna" innovates by using performance as research and as an effective dissemination tool. Alongside generating a major monograph, the project re-stages "Cupid’s Banishment" (performed for Anna in 1617), bringing together undergraduate actors, academics, heritage workers, and members of the public to generate broad interest in Anna and female patronage, giving new significance to European women’s heritage.

Keywords: early modern,art history,literary studies,performance,patronage,material culture,female agency,european cultural exchange,national identity,cultural translation,court society,rituals
HyperCube: Gram scale production of ferrite nanocubes and thermo-responsive polymer coated nanocubes for medical applications and further exploitation in other hyperthermia fields (HyperCube)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Italy
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2020-07-01
End date: 2021-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

This project aims at the scale up production, characterization, future commercialization and clinical translation of magnetic iron oxides nanocubes of high magnetic and structural quality and the design and production of an in-flow set up for the further functionalization of the nanocubes with a thermo-responsive (TR) polymer shell. The nanocubes and TR-nanocubes are aimed to be used primarily as heat mediators in magnetic hyperthermia (MH) and as heat-mediated drug agents for the delivery of chemotherapeutic drugs in a heat triggered-mediated chemotherapy for the treatment of tumors. Their use as contrast agents in magnetic resonance imaging (MRI) and magnetic particle imaging (MPI) stands as secondary applications and it will also be relevant in this project. Indeed, given the control over the materials, the scale up synthesis of nanocubes and the in-flow production of TR-nanocubes, we will deliver an unprecedented benchmark scaled product of nanocubes with optimal magneto-heat properties that shall ensure the transition of such materials towards the market and the clinics. In comparison to the standardly used and commercially available magnetic nanoparticles, the high magneto-heat performances at clinically safe magnetic radiofrequency, of such nanocubes will impact the treatment of tumor by MH, by multiple aspects: i) requiring less dose of magnetic materials to be injected intratumorally; ii) unique actuation of dual combination therapy of MH and local heat-triggered drug release, which also will favor a more efficacious therapy at reduced dose of magnetic materials; iii) further degradation and clearance of the heat-mediator nanocubes thus enabling the further investigation of tumour progression by MRI, overcoming the current limitation of iron oxide nanoparticles now employed in MH for the treatment of Glioblastoma Multiforme. Instead, their magnetic response at frequency range of 20-40 kHz will make them appealing as contrast agents in MPI.

Keywords: magnetic hyperthermia,magnetic nanoparticles,drug delivery,thermo responsive polymers,tumor treatment,hyperthermia