Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Baeyer Villiger Monooxygenases as Biocatalytic Parts for Monomers of New Lactone-based Polymeric Materials (Monopoly)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-07-15
End date: 2021-10-09
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

Recent advances in the development of both experimental and computational protein engineering tools have enabled a number of further successes in the development of biocatalysts ready for large-scale applications.The production of monomers from cheap, readily available components (e.g. terpenoids) for sustainable biopolymer synthesis is a growing area of interest. Biomaterials composed of lactone monomers have been used to produce polyurethanes.The present research proposal is focused on the deep understanding of catalysis by newly identified BVMO enzymes, realized through detailed structural and functional analysis of enzyme mechanisms and substrate/coenzyme recognition. This project will involve multidisciplinary training, with clear objectives in the technical areas of synthetic biology, proteomics, structural biology and biophysical chemistry. This project will allow me to work on structure/function relationship of proteins and to extend my knowledge in metabolic pathway engineering especially in understanding of monooxygenases.The objective will be to identify new Baeyer Villiger monooxygenases biocatalysts that have the appropriate biocatalytic and stability characteristics to enable lactone monomer synthesis. The methods would generate novel structural and biocatalytic data to provide a comprehensive toolkit of flavin-dependent BayerVilliger monooxygenases that are suitable for exploitation in lactone monomer synthesis. These new biocatalysts will be used to construct new strains of E. coli that are capable of producing the target lactone monomers in high yield. The immediate outcomes will be new structural information (native and variant forms of the enzymes); new biocatalytic parameters (reactivity profiles with target substrates; stereoselectivity; conversion; stability; coenzyme specificities) and new lactone producing strains generated from existing monoterpene producing E. coli strains.

Keywords: baeyervilliger monooxygenases,lactone monomer,crystallography
Novel water splitting catalysts for efficient alkaline electrolyzers (ELECTROCAT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Switzerland
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-05-01
End date: 2018-10-31
Duration (months): 18.0
Total project cost (EUR): 149959.0
EU funding (EUR): 149959.0
Participants: 1
Project status: CLOSED

Renewable energies such as solar and wind are intermittent and require efficient storage methods. One of the most promising methods for renewable energy storage is water splitting, which converts these energies into hydrogen fuel. Solar or wind-driven water splitting can be done using electrolyzers, and alkaline electrolyzers are potentially scalable because they do not use precious metal catalysts. However, current alkaline electrolyzers employ catalysts that have low efficiencies and are prone to corrosion. This project aims to apply several novel classes of water splitting catalysts developed in our ERC Starting Grant project in alkaline electrolyzers. The catalysts are inexpensive and have higher energy efficiencies than those employed in commercial alkaline electrolyzers. They are potentially more stable as well. The goal of the project is to provide technology demonstrators for the use of these catalysts in alkaline electrolyzers, which is expected to result in higher efficiencies and stability at a similar cost.

Keywords: energy storage,electrolyzers,catalysts,water splitting,hydrogen evolution,oxygen evolution
A portable MicroNanoBioSystem and Instrument for ultra-fast analysis of pathogens in food: Innovation from LOVE-FOOD lab prototype to a pre-commercial instrument (LoveFood2Market)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Germany,Greece,Greece,Greece,France,France,Czechia
Call: Cross-cutting ICT KETs (H2020-ICT-2015, 2015)
Start date: 2016-02-01
End date: 2019-04-30
Duration (months): 39.0
Total project cost (EUR): 3474732.5
EU funding (EUR): 3151750.0
Participants: 7
Project status: CLOSED

The development of new methodologies advancing the state of the art in foodborne pathogen detection is a challenge for scientists and technologists as well as food industry and consumers. This project aims to meet the challenge by providing a reliable and versatile solution thanks to the convergence of micro-nano-bio systems. The work capitalizes on several innovative concepts which have already been proven to meet the required criteria for fast, low cost and highly sensitive analysis of pathogens in food samples in a previous research project entitled LoveFood. These concepts are gathered on a credit-card size Lab-on-Chip platform, where all necessary steps for bacteria detection are performed on several chips. Specifically, bacteria capture and lysis (one chip), DNA extraction (second chip) and amplification (third chip) and finally pathogenic-DNA detection (fourth chip) can be performed in less than 8 hours and without the need for skilled personnel or large, lab-based dedicated equipment. To proceed for a higher Technology Readiness Level towards the successful commercialization of the current prototype and produce a portable, and rapid platform (targeting total pathogen analysis time 4 hours including a 3 hour pre-enrichment step), we propose to further develop it by integrating the bacteria lysis, DNA purification and amplification modules, as well as the biochip detection platform on a single cartridge, able to perform multi-pathogen analysis (i.e. Salmonella, Listeria, Escherichia coli and Bacillus cereus) in multiple samples. The system will be developed for dairy products and meat analysis, with a strong commitment to produce a pre-industrial prototype by the end of the project.

Keywords: micronanobio system for food pathogen analysis,molecular diagnostics,lab on chip,surface acoustic wave saw biosensors,plasma processing
A Complimentary Inspection Technique based on Computer Tomography and Plenoptic Camera for MEMS Components (CITCOM)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Technologies for Factories of the Future
Action type: Innovation actions
Countries involved: Spain,Germany,Germany,Finland,Sweden,Switzerland,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: In-line measurement and control for micro-/nano-enabled high-volume manufacturing for enhanced reliability (H2020-FOF-2017, 2017)
Start date: 2017-10-01
End date: 2020-12-31
Duration (months): 39.0
Total project cost (EUR): 5641186.2
EU funding (EUR): 4763035.64
Participants: 12
Project status: CLOSED

For the latest generation of micro-fabricated devices that are currently being developed, no suitable in-line production inspection equipment is available, simply because current inspection equipment expects planar processing while most of the devices are often highly 3D in nature e.g. medical. This lack of automated processing feedback makes it difficult to steer process development towards higher yields in micro-components and MEMS production. Another visible problem is the need to document and record process data, even on the individual device level, with the degree of traceability as is required for example, for medical devices fabricated under ISO13485. Both factors in the end limit the possibility of reliable and cost effective manufacturing of MEMS and micro-components. Thus, CITCOM has been proposed to address the industrial needs of MEMS and micro-manufacturing which will offer an in-line production inspection and measurement system for micro-components. The system will be developed and demonstrated at TRL7. The system will be based on optical and X-ray techniques combined with computer tomography and advance robotic system capable of analyzing defects that occur in production of micro components e.g. stains, debris, fracture, abnormal displacements, chemical composition of surface coatings, surface traces etc. enabling 98% yield and 100% reliability. Ultimately, CITCOM will cut such costs by 60% as it will offer a system with automated knowledge and inspection data based process feedback that will allow the detection and traceability of faults that may occur in MEMS production, especially for critical applications like aerospace, space and healthcare. CITCOM will give Europe a technological and competitive advantage in the growing manufacturing and production industry. The consortium behind this action is strongly driven by industrial need and problem having Philips and Microsemi as end users and validators of the technology.

Keywords: plenoptic camera,nano focus x ray system,mems,inspection,measurement,robotic manipulation
FAil-Safe Electro-mechanical actuation for LAnding Gear (FASE-LAG)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Italy,Spain,Italy,Italy
Call: Electromechanical actuation for landing gear (H2020-CS2-CFP04-2016-02, 2016)
Start date: 2017-07-01
End date: 2022-06-30
Duration (months): 60.0
Total project cost (EUR): 997273.75
EU funding (EUR): 997273.75
Participants: 5
Project status: SIGNED

The adoption of electrical equipment for flight-critical applications in future aircrafts is motivated by a number of economic and environmental considerations. Also thank to several research programs, EMA systems are now viewed as the best candidate for the aircraft of the future because they are: less complex because of the absence of a hydraulic system; better suited to long term storage since there is no leak potential; more energy efficient compared with hydraulic systems; easier to install and maintain (no filtration, no bleeding); less complex to control from a power-distribution and power-management perspective (power is transmitted without mass transfer). The aim of the FASE-LAG project is the development of an electromechanical actuation system (EMAS) for extension-retraction of main and nose landing gears for future SMALL A/C. The EMAS will be characterized by reduced spatial envelope and weight, improved reliability, increased safety margins and testability of the redundant components. In particular, the proposed solution will include key enabling innovative technologies such as: 1) optimized electromechanical actuator (EMA) fail-safe architectures; 2) advanced and reliable electronics; 3) advanced health monitoring system that do not require adding new sensors in the EMA; 4) highly reliable electrical machine with an intrinsic reliable architecture, high performance materials and a fault tolerant design; 5) advanced control algorithms focused on efficiency optimization. The achievement of the targeted TRL5 (technology validated in relevant simulated environment) will be verified at the end of the project according to a validation plan.

Keywords: landing gear
Windshield with improved bird-strike, erosion, de-fogging, de-icing and IR performance (Wimper)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Germany,Germany,Germany
Call: Bird strike - Erosion resistant and fast maintainable windshields (H2020-CS2-CFP04-2016-02, 2016)
Start date: 2017-06-01
End date: 2021-07-31
Duration (months): 50.0
Total project cost (EUR): 733710.0
EU funding (EUR): 600000.0
Participants: 3
Project status: CLOSED

Objective of this project is the development upto the production of a prototype of a new pilot windshield and other windows with the focus on using state of the art technologies and coatings. This includes the complex interface between the airframe and the windshields. Especially, the capabilities versus improved bird-strike, anti-icing, anti-fogging and IR performance are taken into consideration. The consortium consists of 3 partners, all centred in the aeronautic industry with the expertise to develop and manufacture structural lightweight designs. Everyone is an expert on its main field. KRD Sicherheitstechnik GmbH (KRD) is a leading manufacturer of windshields and windows, so far mainly for ground transports (e.g. forestry harvesters, vessels, sport cars) but has contributed with prototypes for helicopter applications as well. Within their product portfolio you can find coated laminated car windshields with heating systems, usable for aeronautic applications for de-icing or de-fogging, too. The coating development for these applications as well as for scratch resistance is done at KRD premises. The Deutsches Zentrum für Luft- und Raumfahrt (DLR), Institute of Structures and Design has the excellence in the design of structural parts as well as the ability to perform simulations and tests to optimize the engineered parts concerning the structural behaviour, particularly under crash and impact loading. The institute will assist in the definition of testing methods and will perform testing sequences and bird-strike tests to evaluate the solutions. The DLR has developed a dummy bird, which will be evaluated during this project compared to real bird. The University of Stuttgart, Institut für Flugzeugbau (USTUTT) is the third partner and specialized in the production and development of structural fibre reinforced parts and their testing against specifications and life cycle analysis. The USTUTT has capacities and expertise in finding accurate coating solutions.

Keywords: windshields,coating,noise reduction,bird strike,polycarbonate
Revealing fair and actionable knowledge from data to support women’s inclusion in transport systems (DIAMOND)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Ireland,Italy,Italy,Spain,Spain,Serbia,Poland,Türkiye,France,France,United Kingdom,United Kingdom
Call: Demographic change and participation of women in transport (H2020-MG-2018-SingleStage-INEA, 2018)
Start date: 2018-11-01
End date: 2022-01-31
Duration (months): 39.0
Total project cost (EUR): 2628408.75
EU funding (EUR): 2628406.0
Participants: 17
Project status: CLOSED

Current transport systems do not sufficiently take into account physical and social characteristics of women in the design of products and services, and in fostering women’s employability in the industry. Technologies such as data mining and analytics, together with the use of elicitation techniques to gather and analyse information from different stakeholders, allow the generation of actionable knowledge for addressing gender-specific needs for transport decision-making, planning tools and methods. DIAMOND will exploit such technological advances and innovations, to (i) analyse real-world scenarios where these open issues exist, and (ii) take concrete action, to create a fair and inclusive transport system. DIAMOND’s main goal is to turn data into actionable knowledge with notions of fairness, in order to progress towards an inclusive and efficient transport system. This objective will be achieved by the development of a methodology based on the collection and analysis of disaggregated data, including new sources, analytics and management techniques. Thus this allows to identify, design and evaluate specific measures for fulfilling the needs and expectations of women as users of different transport modes and as jobholders in the sector. The knowledge gathered in the data analysis will then be fed into a toolbox that will provide recommendations on how to achieve fair inclusiveness for women in each of the identified use-cases. Interdisciplinary analysis combining methods from social sciences and computer science will contribute to fairness of the model and its results (i.e. condition of being free from bias or injustice). To proof actionability, this project will make concrete advances in four real-world scenarios (use-cases) where inclusiveness is currently a central issue: 1.- railways and public multimodal transport, 2.- Vehicle Dynamics control towards autonomous driving, 3.- vehicle sharing and 4.- corporate social responsibility and employment.

Keywords: fair transport,woman in transport,woman talent,notions of fairness,decision support tools,understanding women needs
Development of an Electronic Wireless Safety System for Power Tools (DSES)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Injuries caused by power tools are a major cause of concern. Facial injuries as a result of power tools are very common. There are around 340 million occupational accidents world-wide. Most of these accidents are caused by inattention through repetition, an unexpected event, and inexperience or over confidence. An automatic safety system is a major factor in reducing these accidents. Our company, INFACO SAS, is developing an innovative solution to these challenges - the DSES Wireless safety system. INFACO has been in the power tools industry since 1984 and currently has a turnover of €37.6 million with 60% of that from exports. INFACO has 100 employees. DSES is an automatic safety system, which offers a wireless electronic system giving the user freedom of movement. Our value proposition is, an electronic wireless safety system that can be adapted to different power tools, offering a safety system that is unmatched in the power tools industry. Our target users are Vineyards, Arboriculture, Parks and landscaping market. The current global power tools market is estimated at €25.84 billion in 2016 and is expected to reach €40.29 billion by 2023 growing at a CAGR of 6.5%. Our entry point for our innovation will be the European market, where we already have significant market share in France. Our distribution network covers more than 45 countries and will provide the logistics for market penetration. Our innovation is currently at prototype stage with a compact functional machine. Further validation and tests remain to be done to bring it to market. The purpose of the phase 1 is to carry out feasibility studies before commercialisation. This will allow us to come up with a detailed business plan covering a projected five-year period. This innovation will grow our market share by 5% and increase our turnover to €36.5 million by 2023. It will also create 17 new jobs.

Keywords: dses,electronic wireless safety system,power tools safety system,chainsaw safety system,pruning shears safety system,chain saw rebound safety,compact safety system,skin sensing safety system
Constructing AcTive CitizensHip with European Youth: Policies, Practices, Challenges and Solutions (CATCH-EyoU)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Estonia,Italy,Greece,Sweden,Czechia,United Kingdom,Portugal
Call: Societal and political engagement of young people and their perspectives on Europe (H2020-YOUNG-SOCIETY-2014, 2014)
Start date: 2015-09-01
End date: 2018-09-30
Duration (months): 37.0
Total project cost (EUR): 2498786.0
EU funding (EUR): 2498786.0
Participants: 9
Project status: CLOSED

The proposal will investigate young people’s views of the EU and of their role in building the EU through their participatory practices at EU, national, regional and local levels. These issues will be examined from an interdisciplinary perspective (Political Sciences, Sociology, History, Media and Communications, Education, Psychology) as building blocks for a new and groundbreaking conceptualization and theoretical model of youth active citizenship in the EU, including “psychological” citizenship and practices of social and political engagement. To achieve this aim, the proposal will adopt an innovative approach combining traditional theoretical hypothesis testing with empirical-phenomenological analysis and allowing to integrate the perspectives of young people, as co-producers of knowledge, with those of researchers and other stakeholders. A wide range of research methods will be used including documentary and media analysis, interviews and focus groups, a cross-national longitudinal study, ethnographic case studies of participatory practices and a socially innovative intervention. These quantitative and qualitative methods will allow to develop a new, robust and cutting-edge conceptualization of youth active citizenship in the EU and new evidence-based multilevel integrated theoretical model. This approach will offer a multifaceted understanding of the different factors influencing the perspectives of “native EU citizens” and the ways in which they engage in society, leading to groundbreaking changes in the ways in which youth engagement, participation and active citizenship are understood. Moreover, the project will provide policy makers with a set of evidence-based ideas, recommendations and instruments to integrate young people’s perspectives into various areas of policy-making. The findings of the project will thus fully cover the challenges, scope and impact of bringing the EU closer to its young citizens and boosting their participation.

Keywords: active citizenship,civic development,european identity,participatory approaches