Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
PROBE.LY - Web Application Vulnerability Scanning Suite for Agile Teams (Probe.ly)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Portugal
Call: Engaging SMEs in security research and development (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-04-01
End date: 2018-09-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The number of publicly reported breaches with sensitive and business data exposed, has been increasing significantly year after year. Web application attacks are the most common attack pattern, with 40% of all breaches. These attacks exploit vulnerabilities that were introduced in the applications inadvertently by their developers. The most popular solution companies use to find vulnerabilities is to hire penetration testing services. However, these services are a) costly because they are performed manually and b) to manage all of the findings is very time consuming. Due to these two reasons, companies don’t test the security of their applications as frequently as they should. Probe.ly automates web vulnerability scanning. Our customers can cost effectively scan web applications and efficiently manage the lifecycle of the vulnerabilities found in an intuitive web interface. As opposed to Web Application Penetration testing, Probe.ly, since it is automated, can offer a very competitive price and address a new market of small companies that do not have the budget for penetration testing services. The objective of our proposal is to enhance R&D to create a viable solution that helps companies to identify vulnerabilities in their web applications, contributing to safer applications and a safer Internet. We believe that, as opposed to the majority of our competitors, targeting Developers is the right way, since they are the ones that introduced the vulnerabilities, but also because we can take a more educational role by explaining to them why the vulnerability exists, its impact and how to avoid future problems. Our market is worldwide and is targeted at companies that have a development team and build online services. Our pricing is based on a subscription model (SaaS) with self-onboarding for smaller companies and through a network of resellers to larger companies.

Keywords: application security,penetration testing,vulnerability scanner,saas,vulnerability manager,devops
'Multisensory Ecology': Understanding adaptive trade-offs between vision and olfaction (MUSE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-08-29
End date: 2018-08-28
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Sensory systems enable animals to perceive their worlds and make adaptive decisions for survival. However, finding out about the world outside is energetically expensive: it involves complex sensory systems to collect the information, and dedicated neural systems to process it. Therefore, the benefits of acquiring information need to be balanced against the costs of receiving and processing it. Consequently, evolution has equipped animals with sensory systems that fit their lifestyle and environment, to give them the information they need to enhance their survival and reproduction. However, most, if not all, animals have multiple sensory systems: how should investment in different sensory systems be balanced, and what factors affect the trade-off between investment in different sensory modalities? When environmental constraints limit the usefulness of specific sensory modalities (e.g. living in the dark), shifts in investment in different sensory modalities can occur. What is not known is how trade-offs occur between sensory modalities that are still useful to an animal, but perhaps their relative importance changes according to lifestyle or environmental factors. This project aims to investigate the trade-off that occurs in diurnal species between the visual and olfactory systems, and explain why it occurs. I will use insects as a model system, since their neural structures, ecologies and sensory systems are well studied, and can be easily measured. I will measure the relative size of olfactory and visual systems within insect species, and test if predatory species or those that fly (i.e. species that need to rapidly assess changes in their environment) invest more in vision than olfaction. I will also test if the sizes of neural structures associated with each modality correlate with sensory ability. The project will provide the first concrete evidence that sensory capabilities are traded-off against one another, and identify the reasons why.

Keywords: sensory ecology,animal behaviour,insect neuroethology
integrated Smart GRID Cross-Functional Solutions for Optimized Synergetic Energy Distribution, Utilization Storage Technologies (inteGRIDy)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: A single, smart European electricity grid
Action type: Innovation actions
Countries involved: Italy,Italy,Spain,Spain,Italy,Italy,Italy,Italy,Cyprus,Greece,Romania,Greece,Greece,France,United Kingdom,United Kingdom,Portugal,United Kingdom,United Kingdom,United Kingdom,United Kingdom,Portugal,Portugal
Call: Demonstration of smart grid, storage and system integration technologies with increasing share of renewables: distribution system (H2020-LCE-2016-SGS, 2016)
Start date: 2017-01-01
End date: 2021-06-30
Duration (months): 54.0
Total project cost (EUR): 15644559.19
EU funding (EUR): 12329013.0
Participants: 37
Project status: CLOSED

inteGRIDy aims to integrate cutting-edge technologies, solutions and mechanisms in a scalable Cross-Functional Platform connecting energy networks with diverse stakeholders, facilitating optimal and dynamic operation of the Distribution Grid (DG), fostering the stability and coordination of distributed energy resources and enabling collaborative storage schemes within an increasing share of renewables. inteGRIDy will: a) Integrate innovative smart grid technologies, enabling optimal and dynamic operation of the distribution system’s assets within high grid reliability and stability standards b) Validate innovative Demand Response technologies and relevant business models c) Utilize storage technologies and their capabilities to relieve the DG and enable significant avoidance of RES curtailment, enhancing self-consumption and net metering d) Enable interconnection with transport and heat networks, forming Virtual Energy Network synergies ensuring energy security e) Provide modelling & profiling extraction for network topology representation, innovative DR mechanisms and Storage characterization, facilitating decision making in DG’s operations f) Provide predictive, forecasting tools & scenario-based simulation, facilitating an innovative Operation Analysis Framework g) Develop new business and services to create value for distribution domain stakeholders and end users/prosumers in an emerging electricity market. inteGRIDy will impact on: a) operations by reconfigurable topology control & supervision b) market by providing new services c) customer by enhanced engagement through DR mechanisms d) transmission by novel forecasting scenarios for the MV/LV areas e) part of the production incorporating innovative storage targeting the optimum use of RES f) environment by CO2 reduction inteGRIDy approach will be deployed and validated in 6 large-scale and 4 small-scale real-life demonstration covering different climatic zones and markets with different maturity.

Keywords: smart grid integration,demand response optimization,enhanced automation,cross functional platform,visual analytics,predictive control,network modelling and profiling,distribution grid
Clinical development of oral oleylphosphocholine as a new drug for the treatment of Old World Cutaneous Leishmaniasis (TT4CL)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Germany,Iran, Islamic Republic of,Belgium,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: New anti-infective agents for prevention and/or treatment of neglected infectious diseases (NID) (H2020-SC1-2018-Two-Stage-RTD, 2018)
Start date: 2019-05-01
End date: 2023-10-31
Duration (months): 54.0
Total project cost (EUR): 4163942.7
EU funding (EUR): 3753135.56
Participants: 8
Project status: SIGNED

Cutaneous leishmaniasis (CL) is a poverty related, neglected tropical disease, which is without an effective and cheap systemic treatment. The aim of TT4CL is to develop a new orally available drug for treatment of CL aimed towards registration with stringent regulatory authorities. Oleylphosphocholine (OlPC), regarded as a new drug by the FDA, is structurally related to the anti-leishmanial miltefosine. It is being developed as an immediate-release tablet for the treatment of CL and, currently, is the only systemically delivered drug specifically being developed for this indication. OlPC is active in vitro and in vivo against different CL-causing Leishmania parasite species and shows curative advantage over miltefosine in rodent models of leishmaniasis. The primary objective of this study is to complete the pre-clinical package that is essential for the subsequent clinical development of OlPC. The project will aim to optimize the synthesis and formulation of OlPC, including stability testing that is appropriate for tropical climates. It will include in vitro drug sensitivity analyses in parasites causing CL (Leishmania tropica and L. major) in the Islamic Republic of Iran, with our endemic-country partner. Comparative studies in animal models with existing anti-leishmanial compounds will establish efficacy advantages and determine pharmacokinetic-pharmacodynamic relationships for OlPC. Phase 1 studies will confirm tolerability and pharmacokinetics of single doses and multiple dosing regimens. Results will be used to guide decisions by future partners on the clinical development of OlPC. This proposal directly addresses the priorities highlighted in this H2020 call. To our knowledge, we are the only consortium that is implementing this type of approach, and there is no other interest in the pharmaceutical sector to carry out a development programme for the oral treatment of CL.

Keywords: leishmaniasis,drug development,preclinical,phase i
How does surprise influence cognition and behavior? (SURPRISE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-08-01
End date: 2026-07-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Humans, like many other species, build models of themselves and their environment, to understand the past and predict the future. These models are constantly evaluated and updated based on new, surprising input. Surprise (i.e., the distance between one’s prior and current beliefs) appears an essential ingredient in various cognitive faculties such as perception, learning, motivation and action and it strongly drives brain activity in both sub-cortical and cortical networks underlying goal-directed behavior. Yet, we currently lack a good understanding of the form and function of surprise signals in the brain. The overall aim of this research proposal is to elucidate how surprise is computed within sensory circuits and how it influences information seeking behavior. To achieve this, I will: 1) test the theoretical proposition that surprise signals emerge from the discrepancy between prediction signals and input signals that are represented in distinct layers of the neocortex, using ultra-high field neuroimaging in human volunteers; 2) investigate how sensory surprise signals may be communicated to downstream areas to update the brain’s attentional sampling policies; and 3) investigate the relationship between sensory surprise and the explicit drive for information that we call curiosity. This proposal bridges several levels of analysis (from laminar circuit models that calculate sensory surprise to systems neuroscience and computational models of behavior) and several cognitive domains (perception, attention, motivation and curiosity). This multi-scale and multi-method investigation of surprise signals is critical for a more complete and integrated understanding of what may be one of the most important drivers of cognition and behavior.

Keywords: prediction,surprise,curiosity,information seeking
Hyper/Hypo Coagulability Assessment Photonic Integrated Chip based Point of Care (C-POC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2015, 2015)
Start date: 2015-07-01
End date: 2015-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

DAS Photonics (http://www.dasphotonics.com/) is a young SME company with about 37 employees and 3M€ total income in 2014. Since 2008 the company works in the field of nanophotonic biosensors, field where we propose the following opportunity: “Bleeding and thrombosis kill together more people than any other causes. The coagulation system, through the formation of thrombin is pivotal in these pathologies. Therefore, the main objective of the overall innovation project is to develop, validate, and commercialise a new diagnostic tool (C-POC) based on the assessment of thrombin generation and simultaneously measurement of several biomarkers of hyper/hypo coagulability using a Photonic Integrated Chip (PIC). The thrombin generation assay is completed with two different sets of measurements, natural coagulation/anticoagulation factor assays and measurement of antiThrombin/antiFactor Xa drug levels. Consequently, a common test for anticoagulants monitoring including heparins and direct oral anticoagulants will be available. PIC based solution will provide an accurate diagnostic and/or patient evaluation with capacity for cost-effective, high sample throughput screening and point-of-care diagnosis. The proposed approach will reduce the occurrence of clinical events in stroke and systemic embolism providing gains in survival and quality of life. The incremental cost-effectiveness ratio is about a 20% per quality-adjusted life year gained when compared to current prescribing pattern. As a consequence, the social costs will be also reduced by providing extensively the C-POC solution to the First Point of Healthcare reducing in this way the risk of both thrombotic events and haemorrhages.

Keywords: develop,validate,commercialise,diagnostic tool,thrombin generation,simultaneously measurement of several biomarkers of hyper,hypo coagulability,photonic integrated chip pic
Nano Voltage Sensors (NVS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany,Israel,France,United States
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2016-01-01
End date: 2021-06-30
Duration (months): 66.0
Total project cost (EUR): 3497553.0
EU funding (EUR): 2772553.0
Participants: 5
Project status: CLOSED

To understand how the brain works, tools need to be developed that will allow neuroscientists to investigate how interactions between individual neurons lead to emergent networks. Towards this goal, we will develop targetable voltage sensing nanorods that self-insert into the cell membrane and optically and non-invasively record action potentials at the single particle and nanoscale level, at multiple sites and across a large field-of-view. In semiconductors, absorption and emission band edges are modulated by an external electric field, even more so when optically excited electron-hole pairs are confined, giving rise to the quantum confined Stark effect. The physical origin of this effect is in the separation of photoexcited charges, creating a dipole that opposes the external field. The proposed sensors will optically record action potential with unique advantages not offered by other methods: much larger voltage sensitivity, high brightness, and hence single-particle voltage sensitivity, large spectral shift (affording noise-immune ratiometric measurements), fast temporal response, minimal photobleaching, large Stokes shifts, large two-photon excitation cross sections, excellent performance in the NIR, and compatibility with lifetime imaging. The proposed sensors could afford, for example, the recording of pre- and post-synaptic membrane potentials, sub-threshold events, ultrafast spiking, individual ion channel activity, or a release of ions from single Ca+2 stores. In addition, deep tissue imaging could be afforded by two photon microscopy and far-field non-linear temporal focusing combined with lifetime imaging. Here we seek to optimize all aspects of the sensors’ synthesis, functionalization, delivery, targeting and detection, in order to provide neuroscientists and physiologists a viable and user-friendly technology that will be generally useful for the study of action potential signals in the brain and in healthy or diseased heart and muscle tissues.

Keywords: biophysics,electrophysiology,neurobiology,single molecule spectroscopy,physical chemistry,analytical chemistry,method development in chemistry,physical chemistry of biological systems
Archaeological Automatic Interpretation and Documentation of cEramics (ArchAIDE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Reflective societies - cultural heritage and European identity
Action type: Innovation actions
Countries involved: Germany,Spain,Israel,Italy,Spain,Spain,Italy,United Kingdom
Call: Innovation ecosystems of digital cultural assets (H2020-REFLECTIVE-6-2015, 2015)
Start date: 2016-06-01
End date: 2019-05-31
Duration (months): 36.0
Total project cost (EUR): 2635266.99
EU funding (EUR): 2460376.75
Participants: 9
Project status: CLOSED

The objectives of ArchAIDE are to support the classification and interpretation work of archaeologists with innovative computer-based tools, able to provide the user with features for the semi-automatic description and matching of potsherds over the huge existing ceramic catalogues. Pottery classification is of fundamental importance for the comprehension and dating of the archaeological contexts, and for understanding production, trade flows and social interactions, but it requires complex skills and it is a very time consuming activity, both for researchers and professionals. This tool would revolutionise archaeologists habits, behaviours and expectations, would meet real user needs and generate economic benefits, reducing time and costs, would create societal benefits from cultural heritage, improving access, re-use and exploitation of the digital cultural heritage in a sustainable way. These objectives will be achieved through the development of: - an as-automatic-as-possible procedure to transform the paper catalogues in a digital description, to be used as a data pool for search and retrieval process; - a tool (mainly designed for mobile devices) that will support archaeologists in recognising and classifying potsherds during excavation and post-excavation analysis, through an easy-to-use interface and efficient algorithms for characterization, search and retrieval of the visual/geometrical correspondences; - an automatic procedure to derive a complete potsherd’s identity card by transforming the data collected into a formatted electronic document, printable or visual; - a web-based real-time data visualization to improve access to archaeological heritage and generate new understanding; - an open archive to allow the archival and re-use of archaeological data, transforming them into common heritage and permitting economic sustainability. Those instruments will be tested and assessed on real-cases scenarios, paving the way to future exploitation.

Keywords: archaeology,classification,documentation,multimedia,shape based recognition,search and retrieval,social benefits,sustainability,sharing,open data,open access,cross lingual,collaboration
Strategic U-Turns between the EU and Russia: Explanatory Prospects of Prospect Theory (EUEaPRU)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The project attempts to test the potential of prospect theory in explaining the strategic choices of countries located in the common neighbourhood between the European Union (EU) and Russia. Under what conditions ruling elites in Eastern Partnership (EaP) countries select EU or Eurasian Economic Union (EaEU) as integration projects? The theoretical expectation is that different values of gains and losses, judged against a given "reference point", are associated with one or another integration project and may be at work in the selection of strategic choices of EaP countries. Prospect theory, a Nobel Prize-winning theoretical construct, has roots in cognitive psychology, but it has uncovered its extraordinary potential to explain decisions under conditions of uncertainly and risk in behavioural economics. The attempts of importing the insights of prospect theory into political science are slowly growing, but there is yet a long way ahead until political science will fully integrate them into its ontological agenda. The proposed project is going to be a pioneering application of prospect theory to the strategic alternatives faced by countries located in the common neighbourhood between the EU and Russia.

Keywords: eastern partnership,strategic choices,russia,prospect theory