Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Amygdala Circuits for Appetitive Conditioning (Amygdala Circuits)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2016-01-01
End date: 2020-12-31
Duration (months): 60.0
Total project cost (EUR): 2497200.0
EU funding (EUR): 2497200.0
Participants: 1
Project status: CLOSED

The project outlined here addresses the fundamental question how the brain encodes and controls behavior. While we have a reasonable understanding of the role of entire brain areas in such processes, and of mechanisms at the molecular and synaptic levels, there is a big gap in our knowledge of how behavior is controlled at the level of defined neuronal circuits. In natural environments, chances for survival depend on learning about possible aversive and appetitive outcomes and on the appropriate behavioral responses. Most studies addressing the underlying mechanisms at the level of neuronal circuits have focused on aversive learning, such as in Pavlovian fear conditioning. Understanding how activity in defined neuronal circuits mediates appetitive learning, as well as how these circuitries are shared and interact with aversive learning circuits, is a central question in the neuroscience of learning and memory and the focus of this grant application. Using a multidisciplinary approach in mice, combining behavioral, in vivo and in vitro electrophysiological, imaging, optogenetic and state-of-the-art viral circuit tracing techniques, we aim at dissecting the neuronal circuitry of appetitive Pavlovian conditioning with a focus on the amygdala, a key brain region important for both aversive and appetitive learning. Ultimately, elucidating these mechanisms at the level of defined neurons and circuits is fundamental not only for an understanding of memory processes in the brain in general, but also to inform a mechanistic approach to psychiatric conditions associated with amygdala dysfunction and dysregulated emotional responses including anxiety and mood disorders.

Keywords: amygdala,neuronal circuits,conditioning,mice,plasticity,learning
Establishment of a Center of Plant Systems Biology and Biotechnology for the translation of fundamental research into sustainable bio-based technologies in Bulgaria (PlantaSYST)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Framework Partnership Agreement
Countries involved: Germany,Germany,Bulgaria,Bulgaria
Call: Teaming (H2020-WIDESPREAD-2014-1, 2014)
Start date: 2015-04-28
End date: 2020-04-27
Duration (months): 60.0
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 6
Project status: CLOSED

Despite the adoption of several reform programs Bulgaria still has the lowest research and innovation index of all EU Member states. Key reasons for Bulgaria’s comparatively poor record of innovation are the insufficient investment in R&D, fluctuating labour force, the almost non-existent linkages between research and the needs of the productive sector and a lack of high-tech science and business parks. With the newly released Smart Specialization Strategy (S3) Bulgaria has an unparalleled opportunity to transform itself into a knowledge-based and R&D-led economy and to turn its research system into an engine of innovation and smart specialization. Plant systems biology, biotechnology, and healthy life have been set in the S3 as top priorities and represent research topics, which are highly addressed in Plovdiv, the biggest academic center in Southern Bulgaria and the most important agricultural region within the country. Most local research units are very productive and competitive at international level harbouring a huge academic and business potential. The goal of the project is to establish a Center of Plant Systems Biology and Biotechnology (CPSBB) in Plovdiv, which will stand at the forefront of plant sciences in Bulgaria. Building on the excellence in plant sciences and biotechnology research of Potsdam, Germany, the CPSBB will implement cutting-edge genetics, functional genomics, metabolomics and bioinformatics technologies to unravel the plant biochemical machinery and translate the scientific knowledge into the food market and industrial applications for development of value-added products with potential markets in medicine, pharmacy and cosmetics. The CPSBB will provide the missing links between academia and industry in the region and will take a leading role in educating next-generation researchers in the fields of plant systems biology and biotechnology. Thus, the CPSBB will fill the scientific and technological gaps identified in the S3 of Bulgaria.

Keywords: plant systems biology
HYbridization via Parallelization based on NOvel Topologies for Innovative Converters (HYPNOTIC)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Italy,Spain,France
Call: Innovative DC/DC converter for HVDC power sources hybridization (H2020-CS2-CFP10-2019-01, 2019)
Start date: 2020-05-01
End date: 2023-03-31
Duration (months): 35.0
Total project cost (EUR): 1044943.75
EU funding (EUR): 822962.5
Participants: 4
Project status: SIGNED

The main objective of HYPNOTIC project is the development of a set of bidirectional converters (at least 5), acting together as only one equipment. Specifically the equipment, composed by several DC/DC bidirectional converters (i.e., the “modules”) plus a supervisor, must be able to reconfigure itself as a consequence of load/source variations, referring to their characteristics and priority, and as a reaction to a fault or to other undesirable events, hence contributing to the maturity of any HVDC distribution Network. This modular architecture will support the design of a scalable converter (30 to 60KW) which could be used to support the integration of new HVDC sources. The HYPNOTIC converter will be connected to HVDC network of the aircraft on one side and to a HVDC battery on the other side which will provide an energy storage source. The converter will implement relevant control techniques to ensure the stability of the network and the battery, and to allow a smooth energy transfer in both directions. Hence, the scope of the project can be summarized as the design and development of a modular bi-directional converter, composed by hardware and software acting together in order to solve the Power Transfer problem of additional DC sources in any HVDC network. Objectives of HYPNOTIC project include: - Development of DC/DC converter cells with enhanced performances, including power density and reconfiguration capabilities. - Development of accurate simulation models, at both “behavioural” and “functional” levels, potentially also integrated with external environments for the aims of the energy management functionalities verification. - Implementation of reliable control laws to allow the parallelization of several HVDC sources - Demonstration of the operation of such converter inside any HVDC network

Keywords: power electronics,converter,aerospace,hvdc,modular,network
An Archimedes-inspired sit-to-stand desk to tackle workplace sedentarism (Archimede)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Recent evidence has shown that a sedentary lifestyle is associated with muscoskeletal disorders, obesity, increased risk of cardiovascular and kidney disease, and cancer. In Europe, 24.5% of the adult population is not physically active, and this is partly caused by sedentary occupations in which workers sit for many hours every day. Around 3 million deaths/year are due to physical inactivity worldwide, and the global cost of sedentary lifestyles is estimated at €43.7 billion in direct health care and €11.3 billion in lost productivity. Height adjustable desks allow the user to work, write and read on the same desk while sitting or standing. Many studies have shown that these tables are effective at reducing whole body discomfort, plus back and neck pain; they improve productivity and the mood, and also increase blood levels of HDL, while decreasing glucose and triglycerides levels, waist circumference, body mass index, and the risk of heart disease. Mara is the only European company offering height adjustable desks with a spring mechanism. These tables are based on four key innovations: a bespoke Archimedes spring, micro-regulation mechanisms paired with a hexagonal torsion bar, a unique application of linear rails with ball bearings, and a tilting countertop mechanism. These technical solutions guarantee silent, smooth, and fast movements, imperceptible micro-regulations, and a totally safe use. The exclusive tilting mechanism allows the rotation of the desks’ countertop to a vertical position for easier storage, transport, and repositioning. Mara’s sit-to-stand desks improve the health and wellbeing of its users, thus reducing the costs and burden of prolonged sitting-related health issues for national health systems, businesses, and society. The company has been on the furniture market since 1960. Since 2010, Mara has focused on the production of a limited number of chairs and tables of very high quality, foldable, and with specialized mechanical part

Keywords: furniture,sit to stand table,sedentarism,adjustable height,archimedean spiral spring,body discomfort,micro regulation mechanisms,ball bearings,tilting countertop mechanism
volumetric medical x-ray imaging at extremely low dose (VOXEL)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Spain,Italy,France,France,Netherlands,Portugal
Call: FET-Open research projects (H2020-FETOPEN-2014-2015-RIA, 2014)
Start date: 2015-06-01
End date: 2019-05-31
Duration (months): 48.0
Total project cost (EUR): 3996875.0
EU funding (EUR): 3996875.0
Participants: 9
Project status: CLOSED

Computerized Tomography (CT) has been one of the greatest achievements in medical imaging, but at the cost of a high, potentially harmful, X-ray irradiation dose. The ultimate goal of VOXEL is to provide an alternative to tomography with a disruptive technology enabling 3D X-ray imaging at very low dose. VOXEL aims at prototyping new cameras that will combine the X-ray penetration and nanometre spatial resolution, easiness to use, afforded by avoiding the rotation of the source or the sample, and extremely low dose for maximum impact on medicine and biology. VOXEL relies on the integration of trans-disciplinary fields in medical imaging, optics, X-ray physics, applied mathematics and value to society through foreseeable commercialization. VOXEL aims at prototyping in parallel a soft X-ray “water window” microscope and a hard X-ray 3D camera for medical applications. While both cameras need groundbreaking development in the underlying physics, only hard X-ray camera has high technological risk (and high societal impact). VOXEL will benefit from the soft X-ray camera thanks to its Biological applications in nano-tomography but also as a test platform for our physical and mathematical models.. The VOXEL team members are leaders in X-ray metrology, wavefront sensing, atomic physic, mathematical computing and 3D medical imaging; with VOXEL we are uniquely positioned to succeed, and to raise the competitiveness of Europe. Doing so by basing the research lead in Portugal with a woman coordinator will be exemplary: beyond the scientific and technological success, thanks to our focus in science and its valorisation, VOXEL will be transformative for scientifically emerging countries.

Keywords: 3d x ray imaging
THE ARCHAEOLOGY OF SOUND OF THE CULTIC THEATRE IN A GREEK CITY IN SICILY (STESICHOROS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-01
End date: 2020-04-30
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

Through this project I aim to assess and recover the lost intangible heritage of cultic theatre acoustics through the acoustic reconstruction of spaces of the past. The acoustics of linear and non-circular theatra in the Greek world have never before been analysed in terms of how and why these spaces were chosen for performance. The project will establish a new line of research at the crossroads of archaeomusicology, architecture, acoustics, and digital technologies to complete a study on these buildings, and will include a specific case study in Sicily. The acoustic reconstruction will also include audio material based on auralisations of ancient instruments. Through this project I will be able to expand my skills in the use of post-processing software and acoustic techniques based on computerised models. This application for the RI fellowship stresses my aspiration to develop new skills in digital heritage. The skills will be extremely useful for my return and reintegration into a longer-term research position in Italy, a nation that is well established in the fields of cultural and digital heritage studies. Securing the RI fellowship will be an important step in my career as an expert researcher with an original profile that blends archaeomusicology and digital heritage. I will be hosted at the Institute for Archaeological and Monumental Heritage of the National Research Council, a centre of excellence for the innovative development of relations between science and technology and different sectors of cultural heritage: the project will provide an opportunity for me to collaborate closely with experts in 3D reconstruction and modelling, augmented reality and applied acoustics. The host will benefit from the intensive collaborations I have built in the USA, and from my research and work in archaeomusicology, as well as in Greek art and archaeology. The project is organised into six work packages that will take place during the two-year duration of the project.

Keywords: cultic theatres,digital heritage,archaeoacoustics
Fostering a Next Generation of European Photovoltaic Society through Open Science (GRECO)

Framework: Horizon 2020 — Science with and for Society
Programme: Integrate society in science and innovation issues, policies and activities in order to integrate citizens' interests and values and to increase the quality, relevance, social acceptability and sustainability of research and innovation outcomes in various fields of activity from social innovation to areas such as biotechnology and nanotechnology
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Spain,Spain,Germany,Bulgaria,Switzerland,Portugal,Brazil
Call: Putting Open Science into action (H2020-SwafS-2017-1, 2017)
Start date: 2018-06-01
End date: 2021-05-31
Duration (months): 36.0
Total project cost (EUR): 3116595.0
EU funding (EUR): 2973220.0
Participants: 11
Project status: CLOSED

GRECO proposal faces the specific challenge of putting Open Science into action in a research project concerning Photovoltaic (PV) Energy Research. Photovoltaics is a realistic R&D area in which to set up and operationalize an Open Science demonstrator. By adopting the model of RRI, definitively we will demonstrate how increased endorsement of PV technology will increase utilization and integration of PV technology into the electric energy supply system. GRECO proposes RRI solutions to increase PV technology useful life, reduce its cost through increased performance and, demonstrate novel competitive solutions in agriculture and buildings. These targets will be met by providing 6 responsible and innovative solutions. The project brings together several expertise from many areas of knowledge in a coalition among all stakeholders of the quadruple helix representing three continents in a research project with research lines at different Technology Readiness Levels (TRLs). The project duration is of 3 years. GRECO is a double OPEN proposal: on one hand this proposal will be open after the evaluation process in order to facilitate Cross-Fertilization with the project in Swafs-10-2017 call that is finally granted, and on the other, it is open to the engagement of citizens, civil society and stakeholders, embedding an MML plan and two Open Innovation actions. How are we going to put into practice OPEN and RRI in GRECO proposal? Our scheme implies Open Science in all its dimensions including Citizen Science. Basically it includes Open Science and RRI approaches in all stages of a research project -planning, evaluation, action and closing- by considering different actions that will ensure an active participation from all relevant stakeholders included the civil society and citizens, to guide in the development of innovative solutions, and to guarantee the future acceptance of the research results.

Keywords: responsible research and innovation,open science pilot,quadruple helix,citizen scientists,mobilizations and mutual learning action plans,eu international cooperation,photovoltaics
Boosting Energy Efficiency Trough Social Smart Grid Network (Socialsmartgrid)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Italy,Italy
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 1750097.5
EU funding (EUR): 1225068.26
Participants: 4
Project status: CLOSED

Since 1995 Fractalgarden has successfully introduced in the Italian market products in the energy monitoring field. ASCOEL is an established SME with more than 20 years of experience in the design and manufacturing of microprocessor-based products. Our companies have been partners in the last years for the development of the ERMES 3.0 datalogger. With the ambition to gain visibility on the market and increase our turnover, we have decided to join capacities again to upgrade this system to a more extended solution: SocialSmartGrid. Recent studies states that the market for home energy management products and services as SocialSmartGrid is gathering momentum and its revenue is expected to grow from 528 € million in 2013 to over 3.000 M€ in 2020 at a compound annual growth rate of 15.2%. SocialSmartGrid is a ground-breaking approach to connect energy providers to their customers through internet to the Smart grids and social networks to boost their energy efficiency up to 20%. The solution is a holistic system based on an energy monitoring unit with internet router integrated which connects to an energy management cloud platform with unique additional features such as social networking, community building and e-commerce marketplace to acquire energy efficient appliances and services. SocialSmartGrid is specially oriented to households and Small and medium business. With only one gadget, our partners from energy and telecommunication utilities will have the possibility to offer to their customer an integrated service of energy management and internet connection. Furthermore, E.ON Energia will support us on the pre-commercial stage through developing a pilot in 100 of its customers, and will be our first sales channel to start our international expansion. We foresee to reach a realistic market share of 0, 6% of the whole European Potential Market, what will imply a cumulative revenue of 38 M€ after 5 years of commercialisation and 22 new direct jobs.

Keywords: energy monitoring,energy efficiency,customer engagement platform,social network,smart,grid
Synthetic Optical Holography (SYNTOH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain,United States
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-01-11
End date: 2019-01-10
Duration (months): 36.0
Total project cost (EUR): 257191.2
EU funding (EUR): 257191.2
Participants: 2
Project status: CLOSED

Holography has paved the way for phase imaging in a variety of wide-field techniques such as optical microscopy. In scanning optical microscopy, however, the serial fashion of image acquisition seems to challenge a direct implementation of traditional holography. Recently, the applicant and supervisors have jointly invented synthetic optical holography (SOH), which is a new holographic modality for fast scanning phase imaging. SOH has already been implemented in scanning near-field microscopy (s-SNOM) (improving imaging speed by a factor of 50 in comparison to standard technology) and in confocal microscopy (enabling optical surface profiling based on the measurement of the optical phase). SOH has great potential for a widespread implementation in diverse scanning microscopy methods, however, the full potential of the method has not been discovered yet. During the outgoing phase at UIUC, we will develop a totally new imaging modality in Stimulated Raman Scattering (SRS). Namely, we will apply SOH to holographically detect the Raman signal to increase speed and sensitivity of current SRS technology. We will furthermore develop novel holographic schemes for spectroscopic phase imaging. Having tested these novel holographic schemes with existing confocal microscopes during the outgoing phase, we will implement them in near-field microscopes at CIC nanoGUNE during the return phase. The goal is to achieve a technological milestone in near-field microscopy, which is the rapid recording of a near-field image where each pixel contains the local amplitude, phase AND spectral information. This new technology, called rapid hyperspectral nanoimaging, is expected to greatly extend the applicability of near-field microscopy for the chemical and structural identification of biological and nanocomposite samples. Results produced by this work could be directly implemented in near-field microscopes, as well as lead to new commercialization of the SOH method in confocal microscopy.

Keywords: holography,scanning microscopy,confocal microscopy,near field microscopy,hyperspectral imaging,synthetic reference wave,phase imaging,spectroscopic imaging