Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
International Political Ecologies of Land in Southeast Europe: Policymaking, everyday experiences, and alternative political imaginaries (IPELSEE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria,Croatia
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 199440.96
EU funding (EUR): 199440.96
Participants: 2
Project status: SIGNED

IPELSEE studies the transformations of land use and land ownership in South East Europe (SEE) in processes of post-socialist transformation, different stages and paths of EU integration, and the restructuring of global capital flows. To do so, it approaches land as differently assembled human-soil relations: as a policy object, an everyday experience, and a site of alternative political imaginaries. It has two aims: (1) to develop an international political-ecology framework capable of studying human–soil relations across multiple scales, and (2) to use that framework to better understand transformations in rural and agricultural land use in Bosnia and Herzegovina, Croatia, and Serbia. While political science and international relations have focused on issues of power, sovereignty, and territory, they have habitually ignored the human-soil relations that make the land they talk about and the rural areas where those relations are grounded. IPELSEE is based in three case studies: a disputed large-scale investment in agricultural land in Serbia, and two projects that reimagine land use in line with alternative political, ecological, social, and economic ideas: a cooperative producing autochthonous grains in BiH, and an EU funded project for conservation and restoration of dry grasslands in Croatia. It uses well-trodden methods (interviews, participatory observation, document analysis) and innovative methodologies (participatory mapping) to investigate human-soil relations and their transformations. Beyond academic contributions to international political ecology within IR, interpretive methods in IR and PolSci, and SEE area studies, communication activities will focus on researched countries to counter the stigmatisation of rural areas and shed light on practices of land use and land ownership that are not only used traditionally but can also contribute to more sustainable and just land use in the future.

Keywords: political ecology,participatory mapping,globalising provincializing social sciences,interpretive methods
Development of a biomimetic prototype to reduce microplastics emissions (SuspensionFlow)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-06-01
End date: 2025-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Within ERC Starting Grant “Mech-Evo-Insect”, we have identified a new principle to filter small particles such as microplastics from water. This filtration principle is used in a variety of organisms but one particular example, the filtration used by suspension feeding fish, is promising to filter diverse waste waters. The idea of the PoC “SuspensionFlow” is to transfer this principle to a filtration unit which can be used in all household washing machines to reduce global microplastics emissions. SuspensionFlow will also serve to further patent relevant discoveries based on the filtration used by suspension feeding fish.
Protein function regulation through inserts for response to biological, chemical and physical signals (PROFI)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Biotechnology and Biosystems E ngineering
Panel description: Biotechnology using all organisms , biotechnology for environment  and food applications, applied plant and animal sciences , bioengineering and synthetic biology , biomass and biofuels , biohazards
Countries involved: Slovenia
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2024-11-01
End date: 2029-10-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

We live in an era of profound excitement for synthetic biology, which is providing insights into the underlying mechanisms of living systems and powerful tools to modify biological and biomimetic systems using innovative design principles. Regulation of protein function based on the recognition of other molecules or environmental conditions is fundamental to all living systems. My vision and the strategic objectives of the project are to develop a modular platform that imparts proteins with the ability to sense diverse signals, thus enabling the regulation of their function and the introduction of novel properties into biological systems. This project aims to explore unique opportunities for regulating protein function through insertions, leveraging modular building blocks with well-known and tunable properties. By combining these building blocks in innovative ways, proteins and biological systems will be engineered to respond to biological, chemical, and physical signals. The specific objectives of the project encompass: 1) design protein responsiveness to pH and RNA molecules, generating RNA sensors and regulating protein function based on cell type- or state-specific RNA molecules; 2) enable proteins to sense the concentration of other proteins, creating concentration-dependent regulatory circuits with a demonstration of biomedical application; 3) construct de novo mechano-responsive proteins, to prepare genetically encoded mechanosensors tolerant to high forces and mechanoresponsive designs of CAR for cancer immunotherapy and 4), design new protein regulators with favorable in vivo properties and regulators of natural proteins. Through several compelling examples in mammalian cells, this project aims to demonstrate the transformative potential of endowing proteins with unique and previously unknown properties, advancing the engineering of biological systems and paving the way for potential therapeutic applications in the field of biomedicine.

Keywords: engineered responsive proteins,rna sensing proteins,mechanoresponsive proteins,cancer immunotherapy,mammalian cells,synthetic biology,therapeutic molecular devices
Cradle-to-Cradle Design of Photovoltaic Modules (C2C-PV)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1962404.0
EU funding (EUR): 1962404.0
Participants: 1
Project status: SIGNED

The project cradle-to-cradle design of photovoltaic modules (C2C-PV) will design and build the first photovoltaic module with full cradle-to-cradle (C2C) recyclability. Achieving this goal requires a radically new design framework. Today’s photovoltaic modules were not designed for recycling, resulting in a recycling process that is slow and delivers materials of inferior quality. In contrast, C2C-PV will apply the principles of green engineering and techno-economics to create a photovoltaic module with minimal environmental impact over multiple generations and economic viability. Unique to this project is the design of a complex opto-electronic device from scratch according to these principles. The scientific challenge of this proposal is to reconcile durability and separability. Current photovoltaic modules follow a “design for immortality” approach, monolithically integrating solar cells in a module to minimize exposure to the environment. This approach pits durability against separability and is the root cause of all challenges in current photovoltaic module recycling. Highly adhesive interfaces make a clean separation of components slow and challenging at best, and often infeasible. Yet, high throughput and retention of material quality are essential for the economic viability of recycling. The key to resolving this challenge lies in the choice of materials and the design of interfaces. Following the design principles of C2C, the project C2C-PV will only use materials that can be produced and processed in a close-loop manner, avoid toxicity and scarcity, and are material- energy- and capital efficient. Interface design will focus on eliminating unnecessary adhesion and equip all necessary sealing with a mechanism for separation. Perovskite solar cells and photovoltaic modules will serve as a vehicle for demonstrating multigenerational close-loop recyclability. Tracking material-, energy- and capital flow over multiple generations will allow quantifying and op

Keywords: recycling,photovoltaic energy,cradle to cralde
Nanocarbon-Ionic Liquid-Interfaces for Catalytic Activation of Nitrogen (CILCat)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 1498590.0
EU funding (EUR): 1498590.0
Participants: 1
Project status: SIGNED

Ammonia is one of the most important chemicals in the world. Electrocatalytic reduction of nitrogen (NRR) at ambient conditions is a sustainable alternative for its production to the established energy consuming Haber-Bosch process, relying on hydrogen from fossil sources. The triple bond in dinitrogen is one of the most stable covalent chemical bonds. Conversely, the dissociation of dinitrogen and its chemical conversion is highly demanding. NRR is a carbon-neutral and decentral process that can be carried out wherever renewable electricity, water, and air are available. However, current research on NRR and other electrocatalytic reactions has reached an impasse as improvements based on catalyst design are getting more and more incremental. At this tipping point, CILCat tackles a foreseeable stagnation by constituting a disruptive principle that holds holistic perspectives for the activation of small molecules. The novel concept will go beyond established principles of isolated catalytically active sites. By confining ionic liquid (IL) electrolytes into charged porous carbon materials, an interface will be created, that as a whole serves as catalytic surface. CILCat will contribute to a fundamental understanding of the physicochemical principles of sorption into ILs upon confinement in pores. Targeted catalyst development will follow and the possibility of using the principle for catalytic activation of nitrogen and other molecules will be explored. This innovative approach will then be combined with advanced electrode design. CILCat aims for more than a step towards a future carbon-free nitrogen economy. It is a pioneering attempt to heterogenize homogenous catalysts by rather converting the energy principles of small molecule activation than chemical structures from solution to surfaces. The methodology is transferable to other obstacles in the field of catalysis and the project will lead to a more objective general understanding of reactivity in confined spaces.

Keywords: electrocatalysis porous carbon materials nanoconfinement ionic liquids activation of small molecules
Studying the Microenvironment And Related Targets in Non-Hodgkin's Lymphoma (SMART-NHL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: SIGNED

The tumor microenvironment (TME) plays an essential role in tumor evolution and response to therapy. Understanding the complex network comprising tumor and immune cells is critical for the success of cancer immunotherapy. CLL and MCL are two non-Hodgkin’s lymphomas characterized by accumulating CD5+ small and mature B lymphocytes in peripheral blood, bone marrow, lymph nodes, and extranodal sites. Despite having distinct basic pathogenic mechanisms, they share the cell of origin and molecular alterations, clinical features, and epidemiological characteristics. However, the influence of the crosstalk between tumor cells and the TME on the disease progression and treatment resistance remains poorly understood, hindering the development of novel therapeutic possibilities. This study aims to uncover the intricate interplay between the TME and neoplastic cells in CLL and MCL and exploit its therapeutic use. To achieve this, I will use single-cell RNA sequencing and spatial transcriptomics to analyze the composition of non-tumoral cells in tumor-involved tissues and at different time points of the disease. Next, I will use correlative analyses to identify the molecular and cellular interactions between the tumor cell (epi)genomic configuration and the TME, determining tumor evolution and response to therapy. Finally, I will validate the identified drivers of disease evolution and treatment resistance and examine their potential as a target for treatment using a 3D LN-derived culture system. The findings have the potential to provide a solid basis for establishing new models of patient risk stratification and identify potential therapeutic opportunities targeting interactions between tumor cells and their microenvironment. Conducting this project at the Molecular Pathology of Lymphoid Neoplasms group of Prof. Dr. Elias Campo will provide me an opportunity to acquire essential technical and soft skills vital for advancing my career in research.

Keywords: preclinical medicine,oncology,leukemia,lymphoma,immunotherapy,tumor microenvironment
Neural representation of space: From individual to social place learning in bees (BeeSpace)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1499988.0
EU funding (EUR): 1499988.0
Participants: 1
Project status: SIGNED

With ease, we daily navigate through our places of residence. From any familiar place, we can compute the shortest route to our workplace or to our favorite coffee shop. Additionally, we can flexibly adjust our route, if a road is suddenly blocked. This flexibility in route planning is based on a topological representation of different places in our brain (cognitive map). While place cells, a neuronal substrate of cognitive maps, have been identified in diverse species across the vertebrate lineage, a cognitive map is highly contentious in insects. Among insects, bees, especially, demonstrate remarkable navigational feats including taking novel shortcuts, which requires a highly sophisticated spatial memory. Given their limited neural bandwidth, it is likely that insects use computationally less demanding navigational strategies compared to a cognitive map. Such strategies have been implicated in the ‘insect base model’ which is centered on remembering vectors bound to views of the terrestrial landscape. Although this model can explain many behavioral findings in navigating insects, the underlying neural mechanisms are not entirely understood. Due to technical constraints of monitoring brain activity in freely moving insects, it is unclear how space is represented in the insect brain. With neural recordings from freely foraging bees, I recently identified cells exhibiting a spatial tuning that strikingly resembles the one of vertebrate place cells. These ground-breaking findings represent the foundation for my proposal to study the neural basis of insect navigation. The cutting-edge recording techniques, which I recently developed, will enable me to gain unprecedented insights into how the insect solves navigational tasks. Understanding how insects navigate through their home terrain with numerically simpler neural circuits, will help us to reveal innovative ways to design autonomously navigating vehicles.

Keywords: neuroethology,spatial memory,insects
Colour4CRAFTS - Colour for Combining, Re-engineering, Applying, Futuring, Transforming, Stretching (Colour4CRAFTS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Finland,Estonia,Belgium,France,United Kingdom
Call: Traditional crafts for the future: a new approach (HORIZON-CL2-2022-HERITAGE-01, 2022)
Start date: 2023-07-01
End date: 2026-06-30
Duration (months): 36.0
Total project cost (EUR): 3004000.0
EU funding (EUR): 3004000.0
Participants: 6
Project status: SIGNED

Colour4CRAFTS proposal combines a multidisciplinary team of experts from research institutes and R&D companies to carry out studies of bio-based textile colouration in traditional historic perspective and in combination with cutting-edge technologies of colourants biosynthesis and waterless applications techniques. The researchers are top experts in archaeology and history, textiles and colouration, biotechnology and chemistry, art, craft and education. Research combines methodologies of history, artefact research and cultural studies, art and craft research, natural sciences and futures studies. This creates a manifold basis to understand colouration practices in history and craft context profoundly and create innovative state-of-the-art solutions for the futures’ bio-based practices. Multidisciplinary methodologies enable the development of new research methodological openings. Education and communication have important roles as they create and enable interventions for traditions transformation into futures green industries. This research proposal supports and fosters European cultural heritage and the European cultural and creative industries, and it initiates new high quality biocolourant and colouration businesses in Europe. Research aims to foster craft skills in textile colouration, and transform the traditional processes into sustainable cutting-edge processes, which support futures’ green deal objectives; through research provide new profound knowledge of traditional craft colouration practices in Europe and especially in the North Eastern Baltic area, and by combining this knowledge with novel technologies create innovative colourants and colouration practices. This helps increasing sustainability in craft scale colouration and more broadly in industrial scale textile production; through futures research methodologies project provides futures visions and the path to the most desirable colouration and textile production practices in Europe.

Keywords: craft,textile heritage,dyeing,natural dye,biocolourant,sustainability,waterless dyeing,supercritical carbon dioxide,textile printing,colour chemistry,archaeolgy,futures research
Relativistic Framework for Attosecond Pump-Probe Induced Dynamics (RAPPID)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Slovakia,Norway
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-08-01
End date: 2026-07-31
Duration (months): 24.0
Total project cost (EUR): 165059.52
EU funding (EUR): 165059.52
Participants: 2
Project status: SIGNED

Within RAPPID, I will develop a relativistic real-time time-dependent density functional theory (RT-TDDFT) based approach for simulating out-of-equilibrium processes observed in modern attosecond pump−probe spectroscopies. Their theoretical description presents a formidable task owing to the intricate interplay of electronic and nuclear motions, ionization processes and relativistic effects hallmarked for high energy x-ray photons. Our objective is to address all these challenges through the formulation and implementation of mixed quantum-classical electron-nuclear dynamics based on Ehrenfest approach embedded with adaptive scheme with flexible Gaussians to solve the time-dependent electronic equation-of-motion for capturing ionization processes. The backbone of these developments will be the state-of-the-art relativistic atomic mean-field exact two-component (amfX2C) Hamiltonian within the context of RT-TDDFT. These goals will be achieved by combining my expertise on ab-initio theory of ionization processes with the expertise of Dr. Repisky in development and implementation of novel relativistic approaches. In summary, RAPPID will deliver an advanced relativistic framework which is capable of describing ultrafast electron-nuclear processes including valence and core states for elements across the periodic table, and aligns synergistically with ongoing experimental endeavours performed for instance in European-XFEL or ELI-ALPS.

Keywords: attosecond dynamics,electron nuclear coupling,real time,relativistic hamiltonian,charge transfer,ultrafast processes,beyond born oppenheimer approximation