Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Twisted Perovskites - Control of Spin and Chirality in Highly-luminescent Metal-halide Perovskites (TWIST)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany,Germany
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-04-01
End date: 2025-03-31
Duration (months): 60.0
Total project cost (EUR): 1734713.0
EU funding (EUR): 1047863.56
Participants: 2
Project status: SIGNED

The translation of chirality from molecular to bulk inorganic systems opens many possibilities for new phenomena. The properties of chiral electronic states are interesting scientifically and attractive for applications. While optoelectronic properties of semiconductors are controlled by charge, magnetic materials function by spin. If a material can combine these functionalities, powerful novel applications and large gains in performance are possible in opto-spintronics. Yet, existing magnetic semiconductors often show lower optoelectronic quality or work at low temperature. Development of new systems is a scientific challenge due to the required coordination of spins and control of physical properties of excited states, while minimizing defects. TWIST will demonstrate novel highly-luminescent semiconductors for spin-control and chiral emission that show combined properties of ferromagnets and excellent semiconductors for efficient spin-LEDs at room temperature. To achieve this, TWIST will develop new approaches to control spin and chirality in doped metal-halide perovskites (MHPs) with magnetic elements and molecules, also in chiral superstructures. In 2014, I reported that MHPs are exceptionally bright emitters, which underpins their tolerance to defects and chemical variation, and which recently enabled remarkable doping with transition-metals. Optical spin-control and chiral emission are possible from spin-orbit coupling and Rashba effects, which will enhance spin-order for Curie temperatures towards room temperature. These exceptional properties of MHPs, which have already produced efficient solar cells and LEDs, provide now a unique opportunity for my project. TWIST will use state-of-the art optical and electronic techniques to unravel the fundamental mechanisms how magnetic moments, light and chiral states order and interact in MHPs. The results of TWIST will instigate opto-spintronic applications with novel functionality and lower energy consumption.

Keywords: dilute magnetic semiconductors,sustainable materials,chirality,magnetism,optoelectronics,high resolution ultrafast spectroscopy
Processes and Outcomes of Educational Evaluation from a Cross-Cultural Perspective (POEECCP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-02-01
End date: 2020-04-22
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

The full complexity of educational evaluation at various levels (i.e., system, school, classroom, and student) in different countries has hardly been recognized. It constitutes a tremendous barrier to consolidate theories on evaluation, and for countries to draw on successful experience and implement targeted educational policies for better quality and effectiveness. Important barriers include the insufficient methodology to soundly compare multiple countries and a cultural insensitive approach to unfolding evaluation processes and outcomes. This project aims to provide a comprehensive framework for the dynamics of evaluation with a solid cross-cultural research methodology. Using self-report data in 70 countries/economies in the 2015 Programme for International Student Assessment (PISA), this project delineates the pathways in processes and outcomes of educational evaluation in 70 educational systems by integrating policies at system level, practices in schools and classrooms, and student assessment outcomes with demonstrated comparability of data. Study 1 has a methodological focus to analyze scalable measures and their cross-cultural comparability. It tests whether self-report multiple-item measures from school principals, teachers, and students across countries reach approximate measurement invariance to ensure proper comparisons. Study 2 tests the effects of accountability policy, country affluence at country-level, and various evaluation practices including the feedback mechanisms at school and teacher levels, and the cross-level interactions on a broad range of student outcomes such as achievement, motivation, wellbeing, and test anxiety. This project contributes to theory building on educational evaluation from a cross-cultural perspective and identify effective measures for more targeted educational interventions.

Keywords: education evaluation,data comparability,large scale survey
Enhanced PLB, EGNSS receiver, and MEOLUT, according but beyond the standard, significantly improving the localization in difficult conditions, paving the way to a mass market SAR/Galileo service (SINSIN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Innovation actions
Countries involved: Italy,Israel,Switzerland,France
Call: EGNSS mass market applications (H2020-GALILEO-GSA-2017-1, 2017)
Start date: 2017-11-01
End date: 2021-10-31
Duration (months): 48.0
Total project cost (EUR): 1875500.0
EU funding (EUR): 1312850.0
Participants: 4
Project status: CLOSED

Enhanced Personal Locator Beacon (PLB), embedded EGNSS receiver, and MEOLUT, implementing innovative technologies complying with the Cospas-Sarsat standards yet significantly improving the localization of slow-moving beacons and on-land activated beacons with restricted sky visibility, paving the way to effective mass market terrestrial Search and Rescue services based on SAR/Galileo.

Keywords: cospas sarsat,search and rescue,beacon,meolut,meosar,localization,location determination
Deconstructing Early Christian Metanarratives: Fourth-Century Egyptian Christianity in the Light of Material Evidence (DEChriM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Norway
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-09-01
End date: 2025-08-31
Duration (months): 72.0
Total project cost (EUR): 1718980.0
EU funding (EUR): 1718980.0
Participants: 1
Project status: SIGNED

A massive corpus of unedited archaeological sources collected over the last two decades from the deserts of Egypt, by far the richest available for the fourth century, sheds a radically new light on Christianity in Egypt. Building on this new dataset, DEChriM reassesses phenomena and developments that are defining for Egypt's Christianisation, such as the chronology and dynamics of the evangelisation, the role played in this process by imperial legislation and institutions, the balance between rural and urban Christian communities, the social and cultural profile of the conveyors of Christianity, strategies for negotiating Christian identity, etc. Grounded in the archaeological record, DEChriM addresses also key issues relating to material culture through, among others, producing a catalogue of fourth-century Christian archaeological material (monuments and artefacts), providing absolute dates and occupation sequences for the most significant monuments, systematising chrono-typologically fourth-century Christian architecture, producing a long overdue catalogue of the ceramic production of the fourth century in Egypt or drafting. As suggested already by the pre-treatment of the corpus, the picture of fourth-century Egyptian Christianity emerging from this mass of data shifts the paradigm with which operates the historiography of late antique Egypt. Whilst deconstructing the prevailing metanarratives on fourth-century Christian Egypt, the project aims for hypercontextualised regional micro-narratives valid for some regions of Egypt, but potentially relevant for or extrapolable to other provinces of the Late Roman Empire. An inter- and trans-disciplinary collective endeavour calling upon a variety of disciplines, methods and techniques, DEChriM constitutes the first in-depth regional study in fourth-century Christian archaeology.

Keywords: early christianity,conversion,western desert of egypt,late roman empire,roman army,early christian art,papyrology and ostracology,coptic epigraphy,absolute dating,saharan trade
Tissue-engineering the tumour microenvironment to improve treatment of pancreatic cancer (CHIPIN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2021-04-01
End date: 2026-03-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

My vision is to address a clinical problem with a novel and transformative approach. Using my unique expertise in cell biology, tissue engineering and translational research I will design technology platforms to test new treatments for human pancreatic cancer. Pancreatic tumours are cancers of unmet medical need with 85% of patients dying within 9 months of diagnosis. To find better therapies, we need patient-specific models that mimic the biology of tumour tissues and target interactions between malignant and non-malignant cells. Biomimetic tissue engineering is a powerful approach to generate 3D cancer models, however, only a few scientists use these technologies. Most 3D cultures of human cells include reconstituted matrices that originate from murine tumours containing undefined amounts of extracellular matrix and growth factors. There is no tissue-engineered 3D model that allows control over patient-specific and biomechanical characteristics of the pancreatic tumour microenvironment. I hypothesise that 3D approaches that replicate the native tissue composition and biomechanical properties will behave like real tumours to provide clinically predictive platforms and to test novel treatments that target both malignant and non-malignant cells. To test my hypothesis, I will: •3D-print matrix and cellular elements of the microenvironment of human pancreatic tumours •Develop a cancer-on-a-chip model of liver metastasis •Compare the crosstalk of malignant and other microenvironment components with the human disease •Validate my new platforms with treatments in clinical trials and test novel combination treatments that slow down or reduce tumour growth. In a multidisciplinary project, I will use: •3D printing to build platforms composed of hydrogels, fibrous scaffolds and patient-derived cells •Extracellular matrix molecules for chemical crosslinking into hydrogels •Cancer-on-a-chip models to study tumour metastasis •Imaging, biomechanical and multi-omics analyses.

Keywords: tumour microenvironment,pancreatic cancer,biomaterials,microfluidics,hydrogel,scaffold,patient derived cells
Putting regions on track for carbon neutrality by 2050 (C-Track 50)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Spain,Germany,Austria,Belgium,Hungary,Romania,Croatia,Poland,Greece,Greece,Latvia,France,Portugal
Call: Engaging and activating public authorities (H2020-EE-2017-CSA-PPI, 2017)
Start date: 2018-03-01
End date: 2021-08-31
Duration (months): 42.0
Total project cost (EUR): 1983823.75
EU funding (EUR): 1983823.75
Participants: 13
Project status: CLOSED

The project aims to mobilize and guide public authorities in defining long-term energy policy priorities, promote multi-level governance and support regional and local authorities in developing, financing and implementing ambitious integrated sustainable energy and climate policy action plans in order to achieve climate resilience and carbon neutrality by 2050. This will be achieved through: - Facilitation of the vertical and horizontal multi-level governance cooperation in eleven (11) European countries. - Identification of strategic policy priorities at a national level, fostering multi-level governance to capitalise on synergies and economies of scale for implementing energy efficiency and renewable energy actions. - Capacity building at local/regional level. - Development of at least 116 sustainable energy and climate policy action plans for 2050 at the local and regional level. - Development of at least 105 funding proposals for implementing sustainable energy and climate actions/projects. - Targeted promotion of the concept of carbon neutrality to at least 50,000 relevant stakeholders across Europe. - Support EU policies and initiatives, such as the Global Covenant of Mayors on Energy and Climate. C-TRACK 50 is expected to contribute considerably towards achieving the 2030 and 2050 EU energy and climate targets. C-TRACK 50 relates to the topic EE–09–2017: Engaging and activating public authorities, as it will empower local and regional authorities to develop, finance and implement ambitious sustainable energy and climate resilient plans and actions. C-TRACK 50 addresses the following two actions that are part of the topic’s scope: - Supporting public authorities to foster local integrated energy, transport mobility and land-use planning. - Supporting public authorities to foster multi-level governance, linking up national and sub-national levels for delivering integrated sustainable energy planning and projects to achieve synergies and economies of scale

Keywords: multi governance,capacity building,regional,local authorities,integrated sustainable energy and,climate policy planning
Time, Technology, and Globalization. A study of the role of technology in processes of modernization and globalization using the Press, Big Data, and Computational Research Methodologies (GLOTECH) (GLOTECH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 191149.44
EU funding (EUR): 191149.44
Participants: 1
Project status: SIGNED

Time, Technology, and Globalization. A study of the role of technology in processes of modernization and globalization using the Press, Big Data, and Computational Research Methodologies (GLOTECH), will explore the role of technology as a factor of time standardizations in Western, industrialized societies, as well as a booster of cultural homogenization, and as a consequence, an agent of modernization and globalization. The object of analysis will be the press of different countries. France: Le Figaro, Le Monde, Spain: ABC, Italy: Corriere della Sera, Portugal: Diario de Noticias de Madeira; Switzerland: Neue Zürcher Zeitung, United Kingdom: The Times; The United States: The New York Times, being all of them digitally accessible since their different starting dates of publication around the second half of the nineteenth century. The selected time frame will be 1840-2019, and the methodology will include different computational research methods (Quantitative Narrative Analysis, Semantic Networks, NER, Topic Modelling, Word Embeddings, Sentiment Analysis). GLOTECH is a highly innovative research project that will push the state of the art in Digital Humanities and Computational Social Sciences. It will as well propose computational methodologies that other researchers interested about information behaviour historically can adapt to their own research agendas, therefore being of high value for the research community. It will grant me, the researcher, the possibility of acquiring new competences in computation and transferable skills, that, together with my secondmet at the Competence Centre on Text Mining and Analysis, part of the Joint Research Center of the European Union, will allow me to become a driver of excellence in the European Digital Economy, as well as to actively contribute to advance the European Knowledge Society.

Keywords: computational linguistics,natural language processing,data science,intellectual history,cultural studies,globalization studies,media and communication studies,technology in society
DECIPHERING THE MEMORY OF gd T CELLS: DOES IT HAVE A ROLE IN CROSS-PROTECTION OF BACILLE CALMETTE-GUERIN VACCINATION? (GammaDelta)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-03
End date: 2020-05-02
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

Infectious diseases are one of main global health threats in the 21st century, with antibiotic resistance and specific threats such as Human Immunodeficiency Virus (HIV) and tuberculosis (TB) being of biggest concern to Europe. Vaccination is the most efficient approach to prevent infections. The efficiency of vaccines relies on the memory of the immune system. For decades the ability of an immune cell to “remember” a primary infection and subsequently to respond more effectively to the reinfection was solely attributed to adaptive immune cells. Recent findings showed that innate cells can also develop immune memory. In contrast to adaptive immune cells, the secondary response of innate cells is not pathogen-specific. In both cases the development of memory phenotype is accompanied by epigenetic changes in chromatin structure. These findings raise important questions: what decides about the ability of innate immune cells to mount memory phenotype and which factors trigger the secondary response? Does it lie in the type of receptors involved in the pathogen recognition or in chromatin modifications? “GammaDelta” project aims to answer these questions by studying gamma delta (gd) T cells which share characteristics of both innate and adaptive immune cells. Bacille Calmette-Guerin (BCG) vaccine developed to protect against TB induces memory gd T cells and it has been also shown to have a cross-protective effect. The role of memory gd T cells in this process has not been addressed. By applying traditional immunology techniques and newest high throughput sequencing based methodology I will examine the potential of BCG-induced memory gd T cells for the protective effects of the vaccine and which epigenetic mechanisms underlie this process. This will help to understand the interaction between immunological pathways and epigenetic modifications in innate immune memory, a knowledge necessary for the design of a new generation of more effective vaccines.

Keywords: gamma delta t cells,innate immune memory,transcriptomics of gd t cells,chromatin accessibility in gd t cells,epigenetics,bcg induced cross protection,bcg vaccination
Photon Cross Correlation Spectroscopy (PHOCCS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-05-01
End date: 2016-10-31
Duration (months): 18.0
Total project cost (EUR): 149984.0
EU funding (EUR): 149984.0
Participants: 1
Project status: CLOSED

Across Europe, nearly 250,000 people die every year of sepsis, a severe bloodstream infection. Detecting molecular biomarkers indicative of bacterial infection within a limited time is vital to enable targeted antibiotics therapy, limit the risk of antimicrobial resistance and reduce hospitalization costs. The key to success to fight sepsis is a fast detection technology that avoids the need for nucleic acid amplification processes and circumvents the limitations of fluorescence labelling. The PHOCCS project aims at exploiting novel concepts based on PHOton Cross Correlation Spectroscopy to develop a breakthrough platform for ultra-sensitive detection of DNA biomolecules and assess its transferability into the large molecular diagnostics market. With its unique technology based on dynamic light scattering of noble metal nanoparticles, PHOCCS has several key advantages to enable commercial success: it is fast, quantitative, sensitive, specific and simple to operate. Based upon original and patented intellectual property, PHOCCS is fully targeted to the development of a disruptive technology fundamental in strategic applications of molecular diagnostics to fulfil the industrial market needs. The PHOCCS project will bring the technology to a pre-demonstration stage for DNA sensing to strengthen the commercialization and licensing opportunities.

Keywords: biosensing,nanoparticles,light scattering,biophotonics