Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Disposable well-plate inserts and perfusion chambers for easy-to-use and generic microchannel creation in 3D tissue culture (Design2Flow)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Germany
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2020-03-01
End date: 2021-12-31
Duration (months): 22.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Functional 3D tissue models could replace animal experiments and significantly reduce the cost of over 100 million € that pharmaceutical companies spend on failed drug development every year. The main bottleneck in the in vitro creation of 3D tissues is the need for perfusable vascularization in tissues bigger than 1 mm. So far, no generally applicable product exists for that purpose. This hampers advances in drug development as well as in research. Design2Flow will develop products, which overcome this limitation and enable the individualized on-demand creation of perfusable and therefore larger and more complex tissues. This will fundamentally reform research in life sciences by offering easy-to-use, customizable, perfusable 3D cell culture products of interest to the pharmaceutical industry and research labs. To achieve this goal melt electrowriting will be utilized to fabricate sacrificial scaffolds, which resemble the native microvasculature. The fabricated scaffolds will be combined with insert clips as easy-to-use designs for multiwell plates, which will allow a passive perfusion of the construct to keep the tissue alive without the need for a special pump – a beginner friendly way to start advanced 3D cell culture with basic laboratory equipment, without the need for expensive devices or experienced personal. For customers working with perfusion pumps, the proposed solution will be adapted to perfusion chambers for an active and controllable perfusion of the tissue by flow reactors, mimicking the in vivo blood flow even more accurately. This will provide an advanced and customizable way to create tissues as accurate as possible for physiological cultivation in bioreactors.

Keywords: tissue engineering,microchannel creation,perfusion chamber,well plate insert,vascularization,3d cell culture
Minuscule Texts: Marginalized Voices in Early Medieval Latin Culture (c. 700–c. 1000) (MINiTEXTS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Norway
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2022-01-01
End date: 2026-12-31
Duration (months): 60.0
Total project cost (EUR): 2492450.0
EU funding (EUR): 2492450.0
Participants: 1
Project status: SIGNED

MINiTEXTS seeks to systematically study early medieval minuscule texts, i.e. short texts of which large numbers were added to blank spaces of Latin manuscripts from c. 700 to c. 1000 and which manuscript scholars refer to as “microtexts,” “guest texts,” or “additions.” Unlike such manuscripts’ main texts, minuscule texts are seldom characterized by identifiable authors or easily traceable histories of textual transmission. As a result, textual and cultural historians tended to either neglect them or compartmentalize them within highly specialized disciplines. By contrast, MINiTEXTS examines minuscule texts across commonly accepted disciplinary boundaries, as a unique corpus of practical knowledge deeply embedded in the social praxis of early medieval society. By establishing the first taxonomy of such texts, MINiTEXTS will fill a significant gap in knowledge of their production, use, and functions. Further, MINiTEXTS aspires to understand the “social logic” of minuscule texts as well as the social, religious, and cultural practices that they signify by developing a transferable methodology inspired by theoretical insights and methods of cultural history, material philology, material codicology, performative theory, and digital humanities. By analyzing historical, textual, codicological, and performative contexts of individual minuscule texts and setting the resulting microhistories within a longue durée perspective, MINiTEXTS promises significant gain in the understanding of early medieval heterogenous culture. MINiTEXTS will thus allow the hitherto marginalized voices of early medieval manuscript culture to be articulated in the current debates over several intertwined issues of medieval cultural history, such as the correlation between the norm and diversity in liturgical practices, the interplay among orthodoxy, heterodoxy, and deviance in religious practices, and the relationships among religion, magic, and medicine in medieval culture.

Keywords: early medieval culture,minuscule texts,practical knowledge,knowledge transmission,social practices,religious practices,early medieval liturgy,early medieval magic,early medieval cultures of healing
High Integration of Research Monographs in the European Open Science infrastructure (HIRMEOS)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: e-Infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Germany,Greece,France,France,France,Netherlands,United Kingdom,United Kingdom
Call: User-driven e-infrastructure innovation (H2020-EINFRA-2016-1, 2016)
Start date: 2017-01-01
End date: 2019-06-30
Duration (months): 30.0
Total project cost (EUR): 1988876.88
EU funding (EUR): 1988876.88
Participants: 11
Project status: CLOSED

HIRMEOS will improve five important publishing platforms for the open access monographs in the SSH and enhance their technical capacities and services, rendering technologies and content interoperable and embedding them fully into the European Open Science Cloud. The project focuses on the monograph as a significant mode of scholarly communication in the SSH and tackles the main obstacles of the full integration of important platforms supporting open access monographs and their contents. HIRMEOS will prototype innovative services for monographs in view of full integration in the European Open Science Cloud by providing additional data, links and interactions to the documents, paving the way to new potential tools for research assessment, which is still a major challenge in the SSH. The platforms participating (OpenEdition Books, OAPEN Library, EKT Open Book Press, Ubiquity Press and Göttingen University Press ) will be enriched with tools that enable identification, authentication and interoperability (DOI, ORCID, Fundref), and tools that enrich information and entity extraction (INRIA (N)ERD), the ability to annotate monographs (Hypothes.is), and gather usage and alternative metric data. HIRMEOS will also enrich the technical capacities of the Directory of Open Access Books (DOAB), a most significant indexing service for open access monographs globally, to receive automated information for ingestion, while it will also develop a structured certification system to document monograph peer-review. Partners will develop shared minimum standards for their monograph publications, such that allow the full embedding of technologies and content in the European Science Cloud. Finally, the project will have a catalyst effect in including more disciplines into the Open Science paradigm, widening its boundaries towards the SSH.

Keywords: open access,monographs,social sciences and humanities,digital humanities,open science,digital publishing
Positive City ExChange (CityxChange)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Innovation actions
Countries involved: Germany,Ireland,Spain,Ireland,Italy,Estonia,Ireland,Spain,Spain,Ireland,Ireland,Italy,Norway,Norway,Bulgaria,Romania,Bulgaria,Czechia,Netherlands,United Kingdom
Call: Smart Cities and Communities (H2020-LC-SC3-2018-ES-SCC, 2018)
Start date: 2018-11-01
End date: 2023-10-31
Duration (months): 60.0
Total project cost (EUR): 23939383.5
EU funding (EUR): 19999996.38
Participants: 34
Project status: SIGNED

Trondheim, Limerick, Alba Iulia, Pisek, Sestao, Smolyan and Voru and their industry and research partners are joining forces to co-create the future we want to live in. As aspiring Lighthouse and Follower Cities, respectively, they have detailed out their ambitions into the +CityxChange proposal, which describes a structured approach on how to develop and deploy Positive Energy Blocks and Districts and scale these out as part of the Clean Energy Transition. The approach combines: Prototyping the Future through Integrated Planning and Design; Enabling the Future through Creation of a Common Energy Market; and Accelerating the Future through CommunityxChange with all stakeholders of the city. New forms of integrated spatial, social, political, economic, regulatory, legal, and technological innovations will deliver citizen observatories, innovation playgrounds, regulatory sandboxes, and Bold City Visions to engage civil society, local authorities, industry, and RTOs to scale up from PEBs to PEBs to Positive Energy Cities, supported by a distributed and modular energy system architecture that goes beyond nZEB. On top of this, the consortium will create a new energy market design coupled to consumer-driven innovation, developed in close working cooperation with national regulators, DSOs/CSOs, property developers, and local energy communities. Flexibility will be put at the core of the distributed energy system by creating new micro-grid operation, prosumer-driven Community System Operators, and new markets for peak shaving/RES trading to reduce grid investment needs and curtailment. Their aim is to realize Europe-wide deployment of Positive Energy Districts by 2050 and prepare the way for fully Positive Energy Cities.

Keywords: positive energy districts,smart cities,energy market,energy transition,emaas,community engagement
VoLTE device management platform: enabler for the transition to full-LTE mobile networks and more efficient use of the scarce radio spectrum (VoLTE-DM)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Finland
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-12-01
End date: 2018-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Voice over LTE (VoLTE) technology allows a voice call to be placed over an LTE/4G network. VoLTE is aimed at removing the shortcomings related to LTE networks: (1) it aims to eliminate the need to have voice on one network (2G/3G) and data on another (LTE), thus losing the need for parallel infrastructure (operational costs reduced by 30%) (2) a VoLTE call utilises 50-75% less radio spectrum, meaning that more of the scarce spectrum can be freed up for providing new innovative services. However, delivering VoLTE services has proved to be more difficult than anticipated. Deployment of VoLTE currently increases operators’ operational costs at an alarming rate, largely because it is difficult and expensive to configure and manage service parameters for different phone models and phone firmware versions. As a result, large-scale deployment of VoLTE is hindered and the challenges related to the operation of parallel networks and inefficient use of radio spectrum remain unsolved. Trivore’s VoLTE device management (DM) platform is an enabler for faster and more cost-efficient roll-out of VoLTE over LTE networks. The main task of VoLTE DM server is to configure the correct VoLTE settings on devices attached to the network. Our solution provides 75-90% cost savings in VoLTE deployment and operations, faster service roll-out, more efficient use of radio spectrum and investment payback time of 6-12 months. The core product (client, server, user interfaces, and standard protocols) is ready and was piloted/ certified by mobile network provider and device manufacturer ZTE in 2016 (TRL6). Now we need to start preparing pilots with mobile operators. We have commercial contacts with more than 100 mobile network operators (28 of which are using our other product). We could meet our sales objectives by serving these potential customers alone. We aim to deploy our solution at 100 mobile network operators, generate cumulative revenues of €78 million and create 58 jobs by 2023.

Keywords: mobile operators,volte,device management
Eco-friendly Frame Clips and System Brackets for a fuselage demonstrator (ECO-CLIP)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Spain,Spain
Call: Development of short fibre reinforced thermoplastic airframe clips and brackets using factory waste (H2020-CS2-CFP10-2019-01, 2019)
Start date: 2020-05-01
End date: 2022-10-31
Duration (months): 30.0
Total project cost (EUR): 500000.0
EU funding (EUR): 500000.0
Participants: 2
Project status: SIGNED

ECO-CLIP project aims to demonstrate the technical, environmental and economic feasibility of manufacturing structural parts of aircrafts, specifically frame clips and system brackets, using recycled CF/LMPAEK obtained from factory waste. The overall approach of ECO-CLIP is to develop a short fibre recycled composite based on CF/LMPAEK, the manufacturing process for fabricating structural parts of aircraft (clips and brackets) and the welding technology for a success joining in a fuselage demonstrator avoiding fasteners. The whole product development process and manufacture technology will be validated by LCA/LCC studies. As final result, the new manufacturing processing route will be demonstrated as cost-effective and environmentally favorable by LCA and LCC studies. This can be understood in different stages: • Designing of recycling route to re-use material from factory waste • Material development: exploring different mixtures of %wt recycled %wt virgin CF/LMPAEK to accomplish the structural and mechanical requirements. • Design of manufacturing processes fulfilling the use case scenarios (clips and brackets) • Selected the joining technology for a MFFD • Assessment of developed technology through a study of ecological and economical impact The innovation results from ECO-CLIP project will comprise: development of a new composite material based on short fibre recycled CF/LMPAEK, optimised for injection moulding and 3D-printing, and methodology to redesign structural parts to be installed on a MFFD. These solutions will enable to validate the assessment of the technology, and the viability of the environmental and economical impact.

Keywords: short fibre reinforced thermoplastic,redesign,injection moulding,3d printing,welding
Medical First Responder Training using a Mixed Reality Approach featuring haptic feedback for enhanced realism (MED1stMR)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Increase Europe's resilience to crises and disasters
Action type: Research and Innovation actions
Countries involved: Austria,Spain,Germany,Austria,Spain,Austria,Austria,Belgium,Switzerland,Sweden,Belgium,Sweden,Greece,Switzerland,Netherlands,Portugal
Call: Technologies for first responders (H2020-SU-SEC-2020, 2020)
Start date: 2021-06-01
End date: 2024-05-31
Duration (months): 36.0
Total project cost (EUR): 7832663.75
EU funding (EUR): 7832663.75
Participants: 20
Project status: SIGNED

Mass-casualty incidents with injured persons caused by human-made or by natural disasters are increasing globally. In such situations, medical first responders (MFR) need to perform basic life support and first aid to help stabilize victims until arrival of further support. Proper evaluation of situations, checking and monitoring the vital states, and choosing the most appropriate strategy for proceeding with treatments are challenges. However, current training abilities for such scenarios are limited. The MED1stMR consortium has identified Mixed Reality (MR) training as opportunity to better train and prepare MFRs for disasters. Thus, MED1stMR will develop a new generation of MR training providing haptic feedback through the integration of high-fidelity patient simulation manikins into MR. Thereby, MED1stMR offers a much richer sensory experience bringing MR training closer to reality. To enhance the effectiveness of MR training a physiological signal and trainee behavior feedback loop will be integrated for scenario control. In this respect, wearable technologies with body sensors will be developed allowing to monitor states and behaviour of MFR during training. Together with a model for effective performance in medical emergencies (EPME) this data will enable adapting training to trainee needs, manually or by artificial intelligence driven smart scenarios. Partnering MFR will be included in the project developments by an Agile End User Centred Research Methodology. To this end, MED1stMR will pursue the following pioneering objectives: a) Developing a pioneering MR training approach for enhanced realism, b) Developing effective training scenarios and a training curriculum through user-centred design with cross-sectoral MFR, c) Realisation of a physiological signal and trainee behaviour feedback loop and EPME model for smart scenario control thereby enhancing effectiveness of MR training and d) To position the pioneering MR training approach across Europe

Keywords: mixed reality training,smart wearables,resilience,first responder
Women’s imprisonment, social control and the carceral state – an interdisciplinary study of the experiences of detention (WISCA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2026-10-10
Duration (months): 24.0
Total project cost (EUR): 174806.4
EU funding (EUR): 174806.4
Participants: 1
Project status: SIGNED

Women’s imprisonment, social control and the carceral state – an interdisciplinary study of the experiences of detention Prison research in Germany is largely of a quantitative nature and overwhelmingly based on male prisoners who make up the vast majority of the prison estate. The fact that women are far fewer in number can pose a variety of challenges for prison administrations, often resulting in less favourable treatment as compared to imprisoned men. WISCA responds to the Council of Europe’s call for more research and gender-sensitive monitoring which is attuned to the potential compounding of problems women face in prison. Prison research is mainly based on generalisations from mainstream male prisoners (Howe 1994; Loeber et al 2007) and women have remained largely absent from studies into key penological issues such as legitimacy and order (Bosworth 1996; Liebling 2009). Female prisoners are particularly interesting, however, precisely because many reform agendas are trialled on this relatively small and seemingly more manageable group (Kubiak et al. 2017). While attention has been directed towards the Nordic countries in search for penal reform ideas (Pratt & Eriksson 2015), central European countries have been overlooked despite low imprisonment rates; and little is known about prisoners’ experiences in Germany due to a lack of qualitative research. Further, carceral geography as a newly emerging discipline has so far seen no German data, so this project will provide an expansion of carceral geography and qualitative criminology into the German-speaking interdisciplinary field. Using mainly qualitative research methods with some quantitative elements, WISCA will address these gaps in scholarship by focussing on the experiences of female prisoners in order to expose the dynamics of the penal state, the texture of imprisonment as lived and experienced, and wider networks of social control beyond release.

Keywords: carceral geography,women,prison,post release,social control
OLISSIPO – Fostering Computational Biology Research and Innovation in Lisbon (OLISSIPO)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Germany,Switzerland,France,France,Portugal
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2021-01-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 900000.0
EU funding (EUR): 900000.0
Participants: 5
Project status: SIGNED

The OLISSIPO project aims at enhancing the competences in Computational Biology at INESC-ID and developing it into an international pole of excellence. The objectives are: 1) Enhance INESC-ID research profile and innovation competence in Computational Biology; 2) Provide training to staff and Early Stage Researchers to build a critical mass at the interface of computer science and health research; 3) Establish a leading pole of excellence in Computational Biology in Europe; 4) Support regional initiatives under the SMART specialization strategy for Lisbon and Portugal; and 5) Strengthen and expand the collaborative network between the Twinning partners. The project will reinforce the expertise of the Twinning partners in four interconnected Strategic Areas, strongly rooted in computer sciences and statistical learning and with direct impact on biology and health applications: 1) Single-cell data analysis, modeling and simulation; 2) Mathematical modeling of inter-cell and communities’ interactions; 3) Bayesian and combinatorial phylogenetic inference of cells and communities; and 4) Translational bioinformatics, data management and software development. The consortium is designed to meet the methodological challenges of analysing whole organisms and how they interact within communities and with the environment. Besides the proponent institution, INESC-ID (Lead: Susana Vinga), it involves three leading institutions and Principal Investigators in Computational Biology: INRIA (Marie-France Sagot), ETH Zurich (Niko Beerenwinkel) and EMBL (Wolfgang Huber). OLISSIPO will have a decisive impact by: 1) Enhancing the scientific and technological capacity of INESC-ID and the scientific profile of its staff; 2) Contributing to the Portuguese SMART specialisation strategy and the UN Sustainable Development Goals; and 3) Reinforcing the international collaborative networks, visibility and attractiveness of INESC-ID.

Keywords: algorithms,statistical learning,omics data,multi scale,multi level,coevolution,inter disciplinarity,software engineering,education,collaboration in complementarity