Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
'Farming God's Way': Cultivation and religious practice in contemporary South Africa (FarGo)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-08-01
End date: 2023-02-23
Duration (months): 36.0
Total project cost (EUR): 328968.0
EU funding (EUR): 328968.0
Participants: 1
Project status: CLOSED

With this project, I will to study how religious agents engage with every-day challenges connected to food security, environmental decline and climate change. Via ethnographic methods, I will examine religious attitudes to environmental concerns through the case of Pentecostal Christian farming in South Africa. By investigating Pentecostal Christians’ methods of combining biblical principles and secular management approaches, I aim to provide a unique analysis of how Christian farming shapes religious practices that strive for social and ecological sustainability. Situated against a dichotomy between man and nature in Christians traditions historically, the proposed project will generate novel theoretical insights into how religious agents’ relationship to materiality today is manifested. Moreover, the project will demonstrate how the interplay between Christianity and farming produce novel social relationships in the intersection of religion, gender and race. As a religious scholar in the intersection of theology and social science, I understand how religious ideas and practices relate to identity-making, culture and social interactions. I have studied Pentecostal Christianity in Eastern Africa, so I have a robust and field-tested methodological and theoretical framework for investigation of Christian farming in South Africa. The Centre of African Studies at UCPH will be the perfect setting for this project due to its expertise on the material aspects of religion as well as climate and environmental changes. At this centre, I will have the opportunity to improve both my professional maturity and interdisciplinary skills. In addition, the fellowship will allow me to develop transferable skills in relation to project management, administration and teaching—skills that will enhance my career prospects within, as well as outside, academia.

Keywords: south africa,pentecostal,charismatic christianity,religion in africa,faith based farming
TWISTING THE BOUNDARIES: ROLE OF TOPOISOMERASE 1 AT THE NUCLEAR LAMINA (TorsionAtLamina)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 175572.48
EU funding (EUR): 175572.48
Participants: 1
Project status: CLOSED

When DNA is transcribed or replicated, torsional stress accumulates on the double helix. This tension must be dissipated by spreading it along the DNA fiber, or it must be removed altogether. One of the main factors responsible for the removal of such stress is DNA Topoisomerase I (Top1), an important target of cancer chemotherapy. When Top1 activity is lost, torsional stress accumulates on transcriptionally active genes and can lead to the formation of non-canonical DNA/RNA hybrid structures called R loops. These structures are emerging as important regulators of genome function and stability. By genome-wide mapping of R loops in human cells, I recently found that depletion of Top1 leads to a marked R loop stabilization, specifically on genes that are anchored to the nuclear lamina. This strongly suggests that attachment of DNA to the nuclear lamina may prevent dissipation of torsional stress, but how this works is still largely unclear. I propose to investigate the causal relationships between torsonal stress, Top1, R-loops and nuclear lamina attachment, taking advantage of a suite of unique genomics techniques developed in the host lab. Specifically, I will: 1) Develop two novel reporter assays to probe the effects of chromatin context (in particular lamina associated chromatin) and Top1 on torsional stress and R loop formation, at thousands of locations in the human genome. 2) Investigate if and how Top1 regulates DNA/nuclear lamina contacts by by means of a novel version of the powerful genome-wide DamID mapping method with much-improved time resolution. My expertise in Top1, R-loops and DNA topology combined with the unique genomics methodologies in the host lab, as well as their expertise in lamina-associated DNA, will lead to a unique synergy that should result in new insights into the relationship between nuclear organization, torsional stress and R loop formation. Moreover, it will yield new methods that will boost scientific progress in this field.

Keywords: nuclear lamina,dna topoisomerase 1,r loop,torsional stress,dna topology,3d genome,lamina associated domain,genome instability
POLE EUROPE ENTREPRISE INNOVATION (MARTINIQUE ET ILES DE GUADELOUPE) (PEEI)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: France,France
Call: INNOVATION-02 for SGA EEN (H2020-EEN-SGA-2015-01-1, 2015)
Start date: 2015-07-01
End date: 2016-12-31
Duration (months): 18.0
Total project cost (EUR): 81523.75
EU funding (EUR): 60968.0
Participants: 3
Project status: CLOSED

Since 2008, Chambers of Commerce and Industry (CCI) of Martinique and Guadeloupe Islands have been involved in the EEN (Enterprise Europe Network). Along with EEN, to foster CCI Martinique and CCI Guadeloupe Islands have been developing a set of services customized for the specific needs of the local enterprises to support their creation, development, sustainable development, international development or the enhancement of their competiveness with ICT and innovation. Over this period, the French Antilles territory has also been strongly developing the innovation support services mainly carried by the dedicated structure Technopole Martinique. Today, to pursue and reinforce this momentum for Antilles’ growth, these players decided to meet within the PEEI (Pôle Europe Entreprise Innovation Antilles) consortium to carry out the EEN missions over the 2015 -2020 period in the French Antilles. Initiated and led by CCI Martinique largely involved in this new dynamic to foster the development of local SMEs, PEEI gathers and capitalises the unique competences of the CCI Martinique and Guadeloupe Islands, which are the best interlocutors to relay EU policies and programmes and provide one-stop shop for all the business needs of the local enterprises, and the expertise of the Technopole Martinique in innovation support services. Over the 2015 -2020 period, PEEI will provide growth-oriented, integrated business and innovation support services, promote EU policies and programmes and provide a communication channel between local SMEs and EU policy making. It will also facilitate access to European and international markets for local SMEs and improve the environment for entrepreneurial activities. The enclosed strategy implementation plan and work plan detail the PEEI proposed activities over the 2015 -2020 period, and more specifically over 2015-2016 period. With the Technopole Martinique competences, PEEI will also provide innovation support activities in the H2020 framework.

Keywords: network,innovation,international development,partnership,network activities promotion,coaching,mentoring,advice,information,sme feedback,eu single information desk,dedicated support
A platform for the generation of human gametes in vitro (germcells)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

According to the World Health Organization, infertility is a medical condition that affects up to 14% of couples under reproductive age. The increase in infertility has led to the exponential rise in the use of assisted reproduction as a route for conceiving a baby, currently representing 1.5% of children born in Europe. Although multiple factors may contribute to infertility, the limited availability of human gametes for its study restricts the capacity of researchers in establishing the causes of this decline. To address this limitation, a talented Fellow with background in physiology of reproduction will join a leading laboratory in developmental biology to conduct multidisciplinary research aimed at developing a platform for the generation of human gametes in the laboratory. A combination of state-of-the-art tools in genomics and cell biology will be used to gain new understanding of how gamete precursors form in vivo, and this knowledge will be used to develop culture systems to generate gametes in vitro. These approaches will equip the Fellow with comprehensive new skills essential for fulfilling these objectives. The transfer of knowledge builds on the host’s expertise in animal biotechnology, the provision of interdisciplinary training in human stem cell differentiation by collaborators, and on the Fellow’s knowledge of reproductive biology. The output of the project will address key societal challenges for the EU in the areas of Health, demographic change and well-being and will contribute to the expansion of the network of experts in biotechnology.

Keywords: germ cells differentiation
Biocompatible and Interactive Artificial Micro- and Nanoswimmers and Their Applications (ComplexSwimmers)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Türkiye,Sweden
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-09-01
End date: 2021-08-31
Duration (months): 60.0
Total project cost (EUR): 1497500.0
EU funding (EUR): 1497500.0
Participants: 2
Project status: CLOSED

Microswimmers, i.e., biological and artificial microscopic objects capable of self-propulsion, have been attracting a growing interest from the biological and physical communities. From the fundamental side, their study can shed light on the far-from-equilibrium physics underlying the adaptive and collective behavior of biological entities such as chemotactic bacteria and eukaryotic cells. From the more applied side, they provide tantalizing options to perform tasks not easily achievable with other available techniques, such as the targeted localization, pick-up and delivery of microscopic and nanoscopic cargoes, e.g., in drug delivery, bioremediation and chemical sensing. However, there are still several open challenges that need to be tackled in order to achieve the full scientific and technological potential of microswimmers in real-life settings. The main challenges are: (1) to identify a biocompatible propulstion mechanism and energy supply capable of lasting for the whole particle life-cycle; (2) to understand their behavior in complex and crowded environments; (3) to learn how to engineer emergent behaviors; and (4) to scale down their dimensions towards the nanoscale. This project aims at tackling these challenges by developing biocompatible microswimmers capable of elaborate behaviors, by engineering their performance when interacting with other particles and with a complex environment, and by developing working nanoswimmers. To achieve these goals, we have laid out a roadmap that will lead us to push the frontiers of the current understanding of active matter both at the mesoscopic and at the nanoscopic scale, and will permit us to develop some technologically disruptive techniques, namely, targeted delivery of cargoes within complex environments, which is of interest for drug delivery and bioremediation, and efficient sorting of chiral nanoparticles, which is of interest for biomedical and pharmaceutical applications.

Keywords: microswimmers,active brownian motion,far from equilibrium physics
Sqetch – easily connecting fashion brands with apparel manufacturers (sqetch)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: SME instrument
Countries involved: Netherlands
Call: SME business model innovation (H2020-SMEINST-1-2015, 2015)
Start date: 2016-03-01
End date: 2016-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Today`s world is constantly speeding the way we live (learn, communicate, entertain or do business). With over 3 billion searches on Google, “to buy” characterises today`s society. People are looking to be always fashion-conscious therefore they go shopping. This puts an important amount of pressure on brands interested to become more and more effective in order to satisfy customer’s expectations – high quality, fair price, short delivery time. Achieving this requires a paradigm shift in the way companies are conducting their business processes. And the fashion industry is no exception! Both fashion brands and apparel manufacturers are facing significant challenges: How to easily find suitable and trustful apparel manufacturers? Are those delivering the expected quality for a fair price? How to turn more fashion brands into new customers? How to confirm a good quality level of manufacturing? Our Sqetch project will offer a concrete solution by providing an innovative online platform which will help more than 170.000 European textile and clothing companies to connect. Our Sqetch project is driving a major change in how a traditional industry adopts actual business models, responding to the EC initiative for this sector: encouraging innovation and maintaining competitiveness. Sqetch positions as an online service to support a sector which employs 1, 6 million people and plays a crucial role in the economy and social well-being in many regions of Europe. The technical innovation resides in the matching algorithm which uses many weighted criteria to find the best matching manufacturer for a brand. The algorithm weighs, 10 times faster than existing solutions, all these criteria against their importance and finds which manufacturer in the database has the greatest match with that project. The result: faster match, easier usability, lower costs for brand and manufacturers. This translates into more innovative and competitive companies, the foundation of growth.

Keywords: fashion brands,manufactures,business models
New generation of chimeric TLR2-NOD agonist compounds for vaccine adjuvants (FusionPAMPs)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-05-01
End date: 2019-04-30
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

New vaccine modalities need to be developed that can activate more potently the immune system, in this regard, adjuvants augment adaptive immune responses and can improve vaccine performance. Aluminium salt (alum) is the most commonly used adjuvant for human vaccination. However, it drives primarily TH2-effector responses and is not effective for vaccines that target mucosal surfaces. Thus, safe and potent adjuvants need to be developed that can increase and direct vaccine-specific immunity. Recent advances in our understanding of innate immune responses are providing opportunities to design better adjuvants. The innate immune system senses microbes through pattern-recognition receptors (PPRs), which include the Toll-like receptors (TLRs), and intracellular NOD-like receptors (NLRs) and C-type lectin-like (CTLs) receptors that are expressed by immune cells. Activation of these receptors leads to the production of cytokines that provide early defences during infection. Cytokines also regulate adaptive immunity by controlling the quantity and quality of B and T cell activation, which in turn results in protective immune responses to pathogens. Pathogen-associated molecular patterns (PAMPs) such as lipopolysaccharides, lipopeptides, and peptidoglycan fragments can activate PPRs and are attractive compounds for the development of new adjuvant. Although during microbial infection many different PRRs are activated, almost all adjuvants that are being developed rely on the stimulation of a single PRR. In this project, we propose that compound adjuvants derived by the covalent linking of two PAMPs (fusion PAMPs), for example, TLR2 and NOD agonists, will ensure that immune cells are being exposed to both, resulting in efficient cross talk of signal transduction pathways and in synergistic immune activation. If so, chimeric immune modulators (fusion PAMPs) can be employed at lower adjuvant concentrations, thereby minimizing unwanted side effects.

Keywords: vaccine adjuvants,tlr2,nod1,nod2,pamps,carbohydrates,immune response,immunization,muropeptides,lipopeptides,listeria monocytogenes,cytokines,chemokines
Farmers’ Adaptation Sustainability in Tunisia through Excellence in Research: FASTER (FASTER)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Spain,Sweden,Tunisia,United Kingdom
Call: Twinning (H2020-WIDESPREAD-05-2017-Twinning, 2017)
Start date: 2018-11-01
End date: 2021-10-31
Duration (months): 36.0
Total project cost (EUR): 998250.0
EU funding (EUR): 998250.0
Participants: 8
Project status: CLOSED

FASTER will reinforce research and knowledge transfer capacity of INRGREF related to innovative land and water management in view of climate change and its implementation through the use of Farm Advisory Systems (FAS). To achieve this, we will develop a sustainable framework for research capacity building, international networking and FAS practice. Strengthening of researchers and technicians of INRGREF and associated centres (IRESA) will be developed by EU partners of established scientific excellence in the topic (CREAF, LU) and demonstrated experience in economic impact and awareness raising (EFB, Vision), and integration into national policies (AVFA). The proposal is structured into 5 work packages, during 3 years and amounting 1million €, including: coordination; capacity building through training and staff exchanges; living lab stablishing through summer schools, e-learning and stakeholder involvement; project sustainability by monitoring, networking and governmental support; and communication through awareness raising and knowledge co-creation. Expected impacts to INRGREF and Tunisian partners are increased number of publications in peer review journals, mobility and international co-funding, increased international reputation, awareness and engagement, new skills and competencies, new services and employment related to FAS, and new research avenues.

Keywords: climate change,land and water management,forest planning,innovation,research capacity building,fas practice,networking
Nanophotonics by Nanocrystals, from integration to single photon operation (Phonsi)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany,Israel,Switzerland,Belgium,Belgium,Belgium,France,France,Netherlands,Netherlands,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 3056430.24
EU funding (EUR): 3056430.2399999998
Participants: 13
Project status: CLOSED

Phonsi is a research and training program on the development of nanophotonic devices by means of colloidal nanocrystals. Working at the cross-roads of nanomaterials and nanophotonics, it brings together multinational and start-up companies with universities and research institutes around a research programme combining the synthesis and analysis of quantum dots (QDs) with the formation of QD-based nanophotonic devices for emitting and detecting light down to the single photon level. The consortium contains complementary, world-leading expertise that crosses research disciplines, attitudes and methodologies such as chemistry/physics/engineering, synthesis/analysis/simulation, lab-scale/industrial scale and scientific discoveries/research valorization. At each level, the project is driven by highly challenging and timely research goals, which are translated into well-defined, collaborative training-through-research projects. These train ESRs in different disciplines, give them the opportunity to work with high end scientific instrumentation and expose them to both academic and non-academic research environments. The research projects are complemented by a varied set of network-wide training events that rely on the active involvement of the trainees and stimulate their self-learning capabilities. Local specialist training addresses complementary skills, which trainees will put into practice by contributing to the training events and dedicated public engagement activities. The deep involvement of non-academic partners, including two recently established spin-offs, creates a vibrant research and training environment that fosters a spirit of research valorization. In this way, the program will enable Europe to train ESRs with the multidisciplinary skills in nanomaterials, nanotechnology and photonics the innovation union needs and to raise public interest in these fields of science and technology that are key to make our future way of living sustainable and comfortable.

Keywords: colloidal quantum dots,bottom up processing,top down processing,excitons,single photon emission,photodetectors,integrated photonics,nanolasers,single photon detectors