Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
REflection Matrix ImagiNg In wave SCiENCE (REMINISCENCE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: France
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-06-01
End date: 2024-11-30
Duration (months): 66.0
Total project cost (EUR): 1999705.0
EU funding (EUR): 1999705.0
Participants: 1
Project status: SIGNED

In wave imaging, we aim at characterizing an unknown environment by actively probing it and then recording the waves reflected by the medium. It is, for example, the principle of ultrasound imaging, optical coherence tomography for light or reflection seismology in geophysics. However, wave propagation from the sensors to the focal plane is often degraded by the heterogeneities of the medium itself. They can induce wave-front distortions (aberrations) and multiple scattering events that can strongly degrade the resolution and the contrast of the image. Aberration and multiple scattering thus constitute the most fundamental limits for imaging in all domains of wave physics. However, the emergence of large-scale sensors array and recent advances in data science pave the way towards a next revolution in wave imaging. In that context, I want to develop a universal matrix approach of wave imaging in heterogeneous media. Such a formalism is actually the perfect tool to capture the input-output correlations of the wave-field with a large network of sensors. This matrix approach will allow to overcome aberrations over large imaging volumes, thus breaking the field-of-view limitations of conventional adaptive focusing methods. It will also lead to the following paradigm shift in wave imaging: Whereas multiple scattering is generally seen as a nightmare for imaging, the matrix approach will take advantage of it for ultra-deep imaging. Besides direct imaging applications, this project will also provide a high-resolution tomography of the wave velocity and a promising characterization tool based on multiple scattering quantification. Based on all these advances, the ultimate goal of this project will be to develop an information theory of wave imaging. Throughout this project, I will apply all these concepts both in optics (for in-depth imaging of biological tissues), ultrasound imaging (for medical diagnosis) and seismology (for monitoring of volcanoes and fault zones).

Keywords: wave propagation,complex media,aberrations,multiple scattering,matrix formalism,information theory,ultrasound imaging,optical coherence tomography,seismology
Innovative tool for personalized treatment of patients with neovascular age-macular degeneration: dosage optimization for long term efficacy treatment (EyeTREAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Action type: Marie Skłodowska-Curie actions
Countries involved: United Kingdom
Call: MSCA Special Needs Allowance (H2020-IBA-MSCA-SNLS-2019, 2019)
Start date: 2019-10-01
End date: 2019-11-30
Duration (months): 2.0
Total project cost (EUR): 956.25
EU funding (EUR): 956.25
Participants: 1
Project status: CLOSED

The Marie Skłodowska-Curie actions pay particular attention to physical accessibility and inclusion and foresee financial support for the additional costs entailed by recruited or seconded researchers with disabilities.

Keywords: dyslexia,learning disability
Role of Aβ Specific Regulatory T cells in harnessing cerebral Aβ clearance in Alzheimer’s Disease (TREGinAD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-04-01
End date: 2020-09-27
Duration (months): 24.0
Total project cost (EUR): 187866.0
EU funding (EUR): 187866.0
Participants: 1
Project status: CLOSED

With populations ageing, Alzheimer’s disease (AD), for which there is still no cure, has become a major public health problem in Europe. This is partly due to the neglect of the role of the immune responses to the build-up of cerebral Aβ-the pathogenic agent triggering AD. Clinical trials for vaccines aimed at reducing cerebral Aβ were accompanied by severe side effects due to improper neuroinflammation. While the input of microglia, the brain resident innate immune sentinels, is becoming clearer, the impact of the adaptive immune system, specifically T cells is still unknown. A promising therapeutic strategy, would be to strengthen Aβ-induced regulatory T cells (Treg), to alter the effector T cell mediated inflammatory response, while promoting clearance of Aβ by microglia. My interdisciplinary project hosted by Trinity College Dublin and supervised by Prof Lynch will draw together both Neuroscience and Immunology. I propose to assess the effect of Aβ-specific Treg on the pathoethiology of AD. To this aim, I will amplify a population of Aβ-specific Treg in the APP/PS1 mouse model of AD and will 1) assess if Aβ-specific Treg can regulate instruction of microglia to clear cerebral Aβ, while keeping inflammation under control, 2) determine if this regulatory effect occurs via paracrine mechanisms from the periphery or if Treg physically enter the CNS and 3) identify other Aβ-specific T cell populations involved in response to cerebral Aβ build-up and in alteration of microglial phagocytic activity. Completion of this project will make a critical contribution to the understanding of the immune response in AD and will pave the way towards safer therapeutic tools. The proposed action will allow the dissemination of my work to both neuroscientists, immunologists, and the general public. I will reinforce my multidisciplinary and inter-sectoral skills, improve my management and teaching experience to establish myself among the leaders of research at ERC level.

Keywords: neuroinflammation,microglia,regulatory t cells,cerebral amyloidosis,transgenic mouse model
The Developing Communicator: Pragmatics, Sense Conventions and Non-Literal Uses of Language (DEVCOM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Spain,Norway
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-09-01
End date: 2025-08-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1485511.0
Participants: 2
Project status: SIGNED

Children are born communicators. A growing body of developmental evidence suggests that the cognitive abilities enabling the expression and comprehension of communicative intentions – so-called pragmatic abilities – which underlie language use and understanding, develop early. However, a puzzling feature of pragmatic development is young children’s difficulties with non-literal uses of language (e.g., “I love you so much I could eat you up!”). How can children be early experts at a range of pragmatically complex tasks requiring attention to speakers’ intentions, but act like ‘literal listeners’ in other contexts? The objective of DEVCOM is to provide an account of the stages and factors involved in children’s developing competence with non-literal uses of language. The project will investigate the novel hypothesis that children’s growing sensitivity to sense conventions, which determine the publicly accepted meaning of words in their language, impedes children’s pragmatic reasoning with non-literal uses in the pre-school years. The empirical data will be gleaned from experimental studies with typically developing children aged 2-7 years, focusing on lexical innovation, lexical modulation, and figurative language, each highlighting the interaction of pragmatic reasoning with sensitivity to sense conventions in a distinct way. Further, the project will investigate whether the persistent difficulties with non-literal uses faced by children with Autism Spectrum Disorder may be linked to the same source. The project will use a set of novel methodologies combining explicit and implicit measures, assuming that while children’s performance on explicit measures is liable to be affected by a growing sensitivity to sense conventions, implicit measures may be more revealing of their actual pragmatic abilities. The empirical results will provide input to a novel theoretical account of pragmatic development that resolves the developmental puzzle of non-literal uses of language.

Keywords: pragmatic development,lexical pragmatics,developmental psychology,sense conventions,non literal uses of language,philosophy of language,atypical pragmatic development,language acquisition
The Algorithmic Security Politics of Computer Vision (SECURITY VISION)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Netherlands
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2021-01-01
End date: 2025-12-31
Duration (months): 60.0
Total project cost (EUR): 1998320.0
EU funding (EUR): 1998320.0
Participants: 1
Project status: SIGNED

How do technologies of computer vision, which promise to replace humans in the understanding of images, work in practice in the field of security, and what are their ethical and political implications? Vision, understood as the capacity not only to see but also to make sense of what is seen, is increasingly being delegated to autonomous computer systems which influence how human operators determine suspicious behaviour. We currently lack an understanding of how these technologies impact governmental and private sector actors, their decision-making, and their accountability as well as the fundamental rights of those who are targeted. This project address these challenges through an innovative theoretical and methodological framework which investigates the theoretical, empirical and political implications of the development of computer vision in the field of security. In order to carry out this task, the project builds on and advances debates at the intersection of critical security studies, science and technology studies, and visual ethnographic practices. Theoretically, the project advances the debates in International Relations and critical security studies by offering a synthetic framework of analysis of socially embedded technical devices. Methodologically, the experimental use of visual ethnography not only as a method of data collection and dissemination, but also of data analysis within a multi-modal research design will advance, through visual practices, debates in International Relations about the status of non-propositional knowledge as well as alternatives modalities of presentation of research. Empirically it will bring a new understanding of the workings of computer vision technologies in the fields of social media content moderation of extremist content, “smart” Closed Circuit Television Vision (CCTV) cameras and “lie detectors” deployed at the border, participating thus to the ethical and political debates in the public sphere.

Keywords: critical security studies,science and technology studies,social practices,computer vision,visual ethnography
Transformative Impact Of BlocKchain tEchnologies iN Public Services (TOKEN)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Innovative societies
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Spain,Italy,Greece,Belgium,Finland,Greece,Belgium,Poland,Luxembourg,Denmark
Call: Transformative impact of disruptive technologies in public services (H2020-SC6-TRANSFORMATIONS-2019, 2019)
Start date: 2020-01-01
End date: 2023-03-31
Duration (months): 39.0
Total project cost (EUR): 3774363.75
EU funding (EUR): 3774363.75
Participants: 18
Project status: SIGNED

'TOKEN' aims at developing an experimental ecosystem to enable the adoption of Distributed Ledger Technologies (DLT) as a driver for the transformation of public services towards an open and collaborative government approach. During 32 months, a multidisciplinary consortium of 11 partners comprising (a) IT developers/RTOs with experience in development of blockchain components/IoT & Big data platforms (FBA, IMEC, VIL, CERTH, FIWARE), (b) blockchain associations (INF), (c) public administrations (AYTOSAN, KATERINI); (d) SSH experts in public management (UC) and (e) think tanks specialised in digital transformation & policy-making (DEMOS) and Open Commons business models (FBR) will develop a Blockchain Platform as a Service Solution (BCPaaS) to be tested in 4 highly replicable application areas that are common to many Public Governments across Europe: public funding distribution; management of public accounts; urban logistics; valorisation of data. BCPaaS implementation will be assessed from a multidimensional perspective (technological, cultural, socio-economic and legal impacts), paying special attention to attitudes shown by public servants, as key individuals in public service provision. BCPaaS architecture will endorse the Next Generation Internet values of trustworthiness, resilience and sustainability and keep the compliance of the privacy-by-design regulation principles as core driver. It will maximise interoperability potential with IoT & Big Data platforms as well as other blockchains. A specific business model, based on Open Commons principles and Distributed Governance, will be elaborated during the second half of the project, and project dissemination will pay specific attention to meaningfully engagement of +30 early adopters, firstly as members of TOKEN Observatory contributing to TOKEN policy learning co-creation, and, secondly, to be invited to join BCPaaS platform after the project ends, and launch roadmaps to bring DLT to other public services.

Keywords: blockchain
RECONFIGURABLE LIGHT ELECTRIC VEHICLE (REFLECTIVE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Innovation actions
Partnership: EGVI (cPPP)
Countries involved: Italy,Austria,Germany,Spain,Italy,Estonia,Cyprus,Slovenia,Finland
Call: Next generation electrified vehicles for urban and suburban use (H2020-LC-GV-2020, 2020)
Start date: 2021-02-01
End date: 2024-01-31
Duration (months): 36.0
Total project cost (EUR): 7576812.5
EU funding (EUR): 5981056.25
Participants: 10
Project status: SIGNED

Transport related emissions and urbanisation are creating an unparalleled demand for less polluting and efficient means of moving. Tackling the challenge is imperative and it calls for comprehensive understanding of the landscape, its every aspect and innovative mindset. It is a well-known fact that electric vehicles are a big part of the solution (combined with renewable energy production). We aim at developing and demonstrating an innovative, modular vehicle concept that is just perfect for the urban needs: zero emission, compact, safe and rightsized for the mission. Furthermore, we aim at intensifying the utilisation of the vehicles through versatile designing to promote, e.g., multipurpose usage and shared concepts. The key technical innovations of our RECONFIGURABLE LIGHT ELECTRIC VEHICLE, REFLECTIVE, vehicle are: 1) modular, scalable, electric powertrain and reconfigurable interiors fit from L7 quadricycles to M1/A vehicles; 2) supreme structural and active safety proven in Euro NCAP crash test and real life experiments of our L7 demonstrator vehicles; 3) added usability and comfortability through adaptable charging solution combining conductive and wireless charging and limited automated features. To conclude, we aim at introducing a L7 demonstration vehicle that meets the highest quality and safety standards with an affordable price making it an irresistible choice for any urban environment and use case. No such solution exists at the market and our primary aim is to bridge this gap.

Keywords: modular powertrain,conductive charging,wireless charging,advanced driver assistance system,structural safety,active safety,automated features,reconfigurable interiors
Enhancing the innovation management capacity of Finnish SMEs by the Enterprise Europe Network in 2015-2016 (FINKAMIE2016)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Finland,Finland
Call: Enhancing the innovation management capacity of SMEs (H2020-Adhoc-2014-20, 2014)
Start date: 2015-01-01
End date: 2016-12-31
Duration (months): 24.0
Total project cost (EUR): 228388.75
EU funding (EUR): 228388.75
Participants: 4
Project status: CLOSED

Lack of innovation management capacity is recognised as an important barrier to creating economic impact (competitiveness, growth and jobs) from innovation activities in SMEs. The general objective of the proposal is to achieve overall long term capacity building in (Finnish) SME’s, particularly to make the innovation system in the companies more efficient and effective and to increase and accelerate the economic returns from innovation in the SMEs. In proposal actions will be identified weaknesses in the innovation capacities of the SME that hinder the realisation of growth opportunities and of the full commercial potential. Hence, the improvement of this innovation management capacity upgrades the economic performance of the most promising SMEs. First specific objective of the project is to provide Key account management services to beneficiaries of the SME instrument. These services aim to identify bottlenecks to the creation of economic impact in companies benefitting from grants by Horizon2020's SME instrument. Based on the needs analysis the Key account management services identify suitable coaches to address the identified bottlenecks and also facilitates the coach-client relationship during the coaching project. Second specific objective is to provide services, which enhance the innovation management capacity of SMEs. This service will increase the efficiency and effectiveness of innovation processes in small and medium sized enterprises with significant innovation activities that could potentially become beneficiaries of European support to research and innovation but would not have effective access to consulting services for innovation management. The service includes an assessment of innovation management capacity and development actions based on the assessment.

Keywords: smes,innovation management,key account management
Mars Phosphorus and LifE (MaPLE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2024-01-20
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: SIGNED

How did life first emerge on Earth? What type of environments did gather all the ingredients for life to occur? Did Mars ever host life? These challenging questions are the base of the Mars Phosphorus and LifE (MaPLE) project, outlined in this proposal. It emerges from the exciting idea that carbonate-rich lakes might have been terrestrial cradles of life, as very recently proposed, with strong implications for the inception of life on Mars. The MaPLE project is an interdisciplinary research that will be carried out at the Spanish Centre for Astrobiology (CAB), in Madrid. Field work, lab simulations, geochemical modelling and space missions data analysis will be combined to study dissolved phosphorus (P), the key element in all forms of life, in a terrestrial carbonate-rich lake, to approach the environmental conditions required for life on Earth and its applicability on early Mars. Results will be compared to data from the recently launched NASA Mars2020 mission, which will land at the Jezero crater in February 2021, one of the few places on Mars where carbonates have been identified. This makes the MaPLE project extremely timely and novel as it will be the first time that both Martian and terrestrial rocks, where life could have arisen, may be evaluated simultaneously. Results may open a new exciting line of investigation that sets carbonate-rich environments as preferential targets in future planetary missions to other planets or moons. This project will be carried out by F. Cañadas, who bets on a return strategy to Spain after a MSc and PhD in UK. It will bring her an exceptional opportunity to thrive in an exciting scientific environment, ideal to expand her solid geochemical background with complementary methodologies and personal skills. Altogether, the MaPLE project will place her in an extraordinary position to become an independent scientist of high international visibility in the very promising and rapidly growing field of Astrobiology.

Keywords: mars,life,phosphorous,archean lakes,carbonate rocks