Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Capture and Reuse Of biogenic gases for Negative-emission - sustainable biofUelS (CRONUS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Greece,Denmark,Italy,France,Spain,Slovenia,Cyprus,United Kingdom
Call: Carbon-negative sustainable biofuel production (HORIZON-CL5-2021-D3-03, 2021)
Start date: 2022-12-01
End date: 2026-08-31
Duration (months): 45.0
Total project cost (EUR): 4390895.0
EU funding (EUR): 4390894.5
Participants: 13
Project status: SIGNED

CRONUS aims to accelerate on the path to sustainable bioenergy and play an important and constructive role in achieving the UN SDGs by incorporating in the biofuels value chain carbon capture, utilisation and storage (CUS) techniques promoting the decarbonisation of the EU economy in accordance to European Green Deal goals. A wide spectrum of biogenic gases CUS technologies (enzymatic capture of CO2, autotrophic algae cultivation, biological CO2 hydrogenation, syngas biomethanation, in-situ biomethanation, biogenic carbon storage by biochar production and soil application) will be validated in lab-scale (TRL4). The proposed technologies will be upscaled to 5 functional prototypes that will operate in relevant environments of biofuels production plants (TRL5). Evaluation of the technical, economic, environmental and social sustainability of the project solutions and services will be performed by exploitation of the latest up-to-date tools, with special emphasis on the sustainability and circularity of the project. A roadmap to market the technologies and services with a strategy to address market segmentation, penetration barriers and opportunities will be drawn. Public and scientific awareness of the project will be raised and all relevant stakeholders will be actively involved in the co-design, co-development and co-implementation of the possible pathways for biogenic effluent gases capture and utilization within the biofuels value chain. CRONUS’ impactful exploitation plan will facilitate the strategic planning of net-negative biofuel production supply chains considering the integration of CRONUS technologies and the results of the sustainability assessment, emphasizing the CO2 footprint, cost-efficiency, and scalability.

Keywords: biogenic gases carbon capture,utilisation and storage,sustainable biofuels
Turning recycled carbon into valuable fuels for all transport sectors by marrying selective plasma and bio-/chemo-catalysis at mild conditions (C2FUe-LS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Spain,France,Belgium,Germany
Call: Development of next generation synthetic renewable fuel technologies (HORIZON-CL5-2024-D3-02, 2024)
Start date: 2025-10-01
End date: 2029-09-30
Duration (months): 48.0
Total project cost (EUR): 4028302.5
EU funding (EUR): 4028302.0
Participants: 7
Project status: SIGNED

+C2Fue-LS aims to develop a direct cold plasma-catalysis pathway, combined with hybrid bio-/nano-catalysis, to efficiently produce alcohols from CO2 recycling, green hydrogen, and renewable electricity. The project focuses on the challenging CO2 plasma-hydrogenation to formaldehyde, followed by its selective conversion to alcohols of precise lengths using a novel formate carboxylase paired with advanced bimetallic nanocatalysts. These catalysts are encapsulated within porous Metal-Organic Frameworks (MOFs) and manufactured as digitally structured modules with hierarchical porous structures, enhancing plasma formation and facilitating substrate and product migration during the CO2-to-alcohol conversion. +C2Fue-LS targets high-efficient and selective production of aviation and shipping fuels operating under mild conditions (≤100 ºC, ambient pressure). By leveraging plasma effects—pioneering in room temperature catalysis—and encapsulating hybrid bio-, chemo-, and nano-catalysts within MOFs and digitally structured modules, the project will significantly reduce the energy barriers and boosts process efficiency and selectivity, producing alcohols as fuels and chemicals without the need of additional purification steps. The project’s modular approach allows for the selective synthesis of various alcohols, including ethanol, under sustainable and energy-efficient conditions. +C2Fue-LS encompasses several key objectives, as (I) Development of innovative plasma-, bio-, nano-, and chemo-catalysts, (II) the design of advanced catalyst carriers with controlled active site distribution, (III) advanced characterization by ex- and in- situ/operando techniques for mechanistic understanding, (IV) lab-scale validation of the technology, including safety assessments, (VI) comprehensive environmental, techno-economic, and socio-economic evaluations. All in all, +C2Fue-LS represents a breakthrough technology in CO2 conversion into valuable alcohols as fuels and added value chemicals.
2D GRAphene-Based devices for BiosensING cancer biomarkers (GraBBIng)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,Australia
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 283433.76
EU funding (EUR): 283433.76
Participants: 2
Project status: TERMINATED

The key research goal of the MSCA PF (Project Acronym - GraBBIng) is to enhance the leadership and research capability of the Marie Curie Fellow Dr.Vanesa Quintano via implementing a highly challenging and innovative research project focused on the development of highly sensitive and selective clinical biosensors based on two-dimensional (2D)-nanomaterial (graphene oxide, GO) to address European Union (EU) and World Health Organization (WHO) raised issues in public health care. Graphene will be used and duly functionalized to work as a sensor for the direct and accurate detection of novel biomarkers for the early diagnosis of lung cancer. 2D nanomaterial research and development will be performed under the supervision of Prof. Rakesh Joshi, Associate Professor at the School of Materials Science and Engineering and leading the Graphene Research Group-UNSW Team Graphene, Australia. Additionally, a one-year return phase especially dedicated to the biosensor optimization and clinical validation will take place under the supervision of Prof. Laura Lechuga, Head of the Nanobiosensors and Bioanalytical Applications Group at the Catalan Institute of Nanoscience and Nanotechnology (ICN2) in Barcelona, Spain. Researcher Dr Vanesa Quintano is expert in nanotechnology and graphene-based biosensors for biomedical applications, Prof. Rakesh is a nanotechnology expert in graphene-based materials and Prof. Lechuga is expert in biosensors and analytical applications. The project implements a set of coordinated actions among its different partners that maximize international collaboration between universities, research centers and industry in different European and worldwide countries. The European competitiveness will be potentiated throughout the project with the exploitation of the research results, ultimately giving high-level EU employment and maintaining the European status quo of high‐level‐knowledge countries.

Keywords: graphene,biosensor,lung cancer,mirna,surface chemistry,device,2d materials,graphene oxide,biomarker,nanomaterials,nanotechnology,nanoscience
A EUROPEAN MULTI-DISCIPLINARY CLINICAL PROJECT MEANT TO IMPROVE THE MANAGEMENT OF PATIENTS WITH POOR PROGNOSTIC OVARIAN CANCER AFTER NEOADJUVANT CHEMOTHERAPY: RESTORING HOPE, SALVAGING LIVES (SALVOVAR)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Cancer
Destination: Cancer
Action type: Research and Innovation actions
Countries involved: France,Spain,Belgium
Call: Pragmatic clinical trials to optimise treatments for patients with refractory cancers (HORIZON-MISS-2022-CANCER-01, 2022)
Start date: 2023-05-01
End date: 2028-04-30
Duration (months): 60.0
Total project cost (EUR): 6823071.75
EU funding (EUR): 6823071.25
Participants: 12
Project status: SIGNED

The standard medical-and-surgical treatment of ovarian carcinoma patients relies on a systemic chemotherapy (carboplatin-paclitaxel), a tumor debulking surgery meant to be complete (no post-operative residual lesion), and a subsequent maintenance treatment with modern targeted agents. Recent studies identified a patient population (~14,000 patients / year in Europe), whose prognostic is poor (5 year-overall survival (OS) <20%) due to a refractory cancer, characterized by a poor chemosensitivity (assessable online with the numeric CA-125 KELIMTM score <1.0), and by a disease found non-resectable disease after 3-4 cycles of chemotherapy. In these patients, there is a high uncertainty about the best treatment adjustments to apply. SALVOVAR is a European project led by HCL, meant 1) to raise the physician awareness, and propose practical and affordable diagnostic tools for identifying these patients, and 2) to assess the utility (OS benefit), acceptability (quality-of-life; patient perception) and affordability (cost-effectiveness, including country coverage policies) of solutions based on adjustments of their medical-and-surgical treatment. These solutions implementable in routine may improve their prognosis, according to recent literature data. The project will be based on a large pragmatic randomized phase III trial, sponsored by ARCAGY-GINECO group, and activated in 6 countries (ENGOT network; ~100 recruiting centers), with the objective of demonstrating an OS benefit with the chemotherapy densification (weekly carboplatine-paclitaxel dose-dense regimen) compared to the continuation of the standard 3-weekly regimen. Total 685 patients treated with the standard neo-adjuvant chemotherapy will be pre-screened to randomize 240 patients. Dissemination, and communication will be carried-on to ensure the quality of the project, and inform the stakeholders, patients, public, health authorities/ payers of the project outcomes, mean to change the practices. This action is part of the Cancer Mission cluster of projects on ‘Diagnosis and treatment’.

Keywords: ovarian cancer chemotherapy debulking surgery survival prognosis ca 125 therapeutic strategy numeric tool patient perception coverage policy
Learning the Universe in the era of Precision Cosmology (LUPCOS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Netherlands,Switzerland
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 187624.32
EU funding (EUR): 187624.32
Participants: 2
Project status: SIGNED

I propose the project LUPCOS (Learning the Universe in the era of Precision COSmology) to be carried out at the Kapteyn Astronomical Institute, University of Groningen, under the mentorship of Prof. Pratika Dayal. The main scientific goal of LUPCOS is to fully capitalize on the upcoming sky-surveys by developing very accurate and highly efficient analytical and semi-numerical models of the Cosmic dawn and the Epoch of Reionization and, finally, employing the latest Machine Learning techniques to obtain the tightest constraints on different cosmological and astrophysical parameters. The workflow of the project is a combination of machine learning techniques and seminumerical/analytical modelling of the early epochs of the Universe, thereby bridging the gap between these fields to maximise scientific output. The objectives will be addressed via three work packages (WPs): First (WP1): improve the state-of-the-art analytical model CosmoReionMC by incorporating more observational data and more detailed Physics related to different complex astrophysical processes during CD and EoR. Second (WP2): Coupling the latest parameter estimation technique with the state-of-the-art semi-numerical galaxy formation model DELPHI to make it suitable for parameter estimation study. Third (WP3): Employ the most recent machine learning technique on the state-of-the-art cosmological N-body simulation data to extract the maximum information; this will work as a precursor project on parameter inference techniques for the upcoming sky surveys. My expertise in analytical modelling of the early Universe and skills in ML techniques, along with the expertise of my proposed supervisor, Prof. P. Dayal, at the Kapteyn, put us in a favourable position for the successful execution of this project. Furthermore, with the training from this fellowship, I will be competent to lead future research groups of my own, paving the way for ground-breaking scientific results with upcoming surveys.

Keywords: epoch of reionization,machine learning techniques
Testing nuclear coalescence with nuclei-antinucleon / antinuclei-nucleon balance measurements at the Large Hadron Collider (Nuclei Balance)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-03-01
End date: 2027-02-28
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 1
Project status: SIGNED

A hot topic at the Large Hadron Collider (LHC) is the production of anti-nuclei. In ultra high-energy collisions at the LHC, nuclei with very low binding energies are not expected to survive the dense and hot final state environment. This project aims to investigate the nuclei and anti-nuclei production in relativistic hadronic collisions at the LHC to test the microscopic mechanism of their production, which is still under debate. In particular, this project would focus on the first experimental measurement of how quantum numbers (in particular baryon number) of produced deuterons are balanced by other hadrons in proton-proton (pp) collisions. One can in this way experimentally test the coalescence hypothesis of nuclei production, directly by measuring if the proton in the deuteron is balanced by an antiproton exactly the same way as for a free proton. If this is the case, then it indicates that the proton in the deuteron is formed in the same way as a free proton. The idea to perform these measurements is presented in this proposal for the first time and has never been performed before. The same measurements can also be compared with the predictions from the famous PYTHIA8 model whose development and maintenance are centered around the Lund University Theory group. The balance is expected to depend on transverse momentum and could depend on multiplicity as this controls the number of final state interactions. To make the highest precision differential measurements, the analysis will use 13.6 TeV pp collision datasets to be taken in Run 3 (2022-2025) with the recently upgraded ALICE detector that can handle rates that are 10-100 times larger than before the upgrade. The ability to perform the measurements takes advantage of the expertise of the fellow and the supervisor who both have a long association with ALICE collaboration at the LHC and has the necessary expertise and network to carry out the measurements.

Keywords: relativistic hadronic collisions,nuclei and anti nuclei production,deuteron production,coalescence,balance of quantum numbers,large hadron collider
Engineered Particles for Chemical Communication (EDISON)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Spain
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 2499193.0
EU funding (EUR): 2499193.0
Participants: 2
Project status: SIGNED

This project aims to the development of communication at the nanoscale and to advance in the understanding of how abiotic micro/nanoparticles can communicate between them and how micro/nanoparticles can communicate with living systems. In this context, an approach for establishing communication at the nanometric level is to mimic how nature communicates. Chemical or molecular communication, based on transmitting and receiving information by means of molecules (chemical messengers) is one of the communication forms used by living organisms. Moreover, many swarm systems found in nature communicate by modifying the environment using a concept called stigmergy. The advantages of nanoparticles that communicate each to another are immediately obvious; they constitute the basis of a dynamically interacting network eventually resulting in certain autonomy of the system. If we would be able to raise the bases for communication between micro/nanoparticles and between micro/nanoparticles and cells, the potential future applications in the biomedical field, environmental research and industry technology are almost unlimited. The project will establish firm handholds for the use of nanoparticles able to communicate from one to another and with cells in different applications. The project will trace, optimise and adapt all single steps from the idea to its implementation into applicable final systems with the aim of targeting issues that are difficult to address with conventional single particles. The project is divided into three WPs. The first work package (WP1) will create the basic elements for chemical communication. In a more complex situation, WP2 will use the tools of WP1 to develop systems able to establish communication between nanoparticles and living systems. Finally, WP3 will generate nano-systems integrating gated nanoparticles and up-to-date electronics to develop new communication structures.
Engineering Photoenzymes for New-to-Nature Asymmetric Radical Processes (PHOTO-BIO-ENG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 193643.28
EU funding (EUR): 193643.28
Participants: 1
Project status: SIGNED

PHOTO-BIO-ENG aims to develop entirely new strategies for the stereoselective synthesis of complex chiral molecules. We will achieve this by combining biocatalysis and photocatalysis to generate photoenzymes for visible-light-driven radical processes. Utilizing directed evolution and high-throughput experimentation, we will create highly efficient and stereoselective photoenzymes capable of catalyzing transformations that are currently inaccessible to small-molecule catalysts and unachievable via ground-state thermal pathways. Our approach will use enzymes as green catalysts and visible light as a renewable energy source, with environmentally benign reaction conditions (ambient temperatures, aqueous solvents). By merging photochemical methodology with enzyme catalysis, we aim to demonstrate novel chemical transformations that produce chiral products with multiple stereocenters and excellent stereocontrol. This project will establish a highly effective and sustainable synthetic methodology, contributing to the advancement of green chemistry practices. Collaboration with Johnson & Johnson will facilitate the development of photoenzymatic processes to yield chiral molecules with biologically relevant scaffolds. PHOTO-BIO-ENG combines the fellow’s experience in enzymatic catalysis and directed evolution with the host’s expertise in photo-triggered asymmetric radical processes. The interdisciplinary nature of the project will significantly enhance the fellow's expertise, providing comprehensive training and positioning them strongly for future career advancements.

Keywords: biocatalysis asymmetric catalysis iminium ions radical chemistry organocatalysis photochemistry protein engineering
Authoritarian Smart City (e-Authopia)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands,Canada
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 263880.0
EU funding (EUR): 263880.0
Participants: 2
Project status: TERMINATED

The smart city fulfils a utopian picture of a future where data-driven, citizen-centred, and just cities thrive. What if this vision of the smart city is combined with the prospect of smart control? What about the sociotechnical imaginaries of authoritarian smart cities? Research on smart cities in authoritarian regimes, for example, in both Saudi Arabia and China, has rarely been critical and has almost never discussed this urban form as authoritarian or surveillant. Even when calls for a comparative global agenda have been issued, authoritarianism has not been a significant component. E-Authopia explores the formation of authoritarian smart cities through the interplay between global smart city trends and domestic policymaking in authoritarian contexts. Through three instrumental case studies of authoritarian smart cities in Turkey, Thailand, and Gabon, I will investigate how the smart city idea is appropriated and localised, how it is positioned within a political system, and how it is translated into governance initiatives. I use semiotic and discursive analysis to study the authoritarian sociotechnical imaginaries of desirable urban futures at the symbolic and language level. Additionally, policy process tracing will be conducted through global pathways of influence and multiple streams framework to illustrate how these imaginaries and visions are localised, concretised, and translated to agenda-setting in policy adoption and development.

Keywords: authoritarian surveillance,smart city,digital governance