Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Numerical Analysis for Stable AI (NumAStAI)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 2498941.0
EU funding (EUR): 2498941.0
Participants: 1
Project status: SIGNED

From a numerical analysis perspective I will identify, quantify and mitigate vulnerabilities in current artificial intelligence (AI) algorithms. Novel mathematical research will emerge along six overlapping axes: Inevitability: rigorously understand the inescapable endgame of the attack-versus-defence paradigm. Under what conditions is it inevitable that adversaries will succeed? Formalizing such conditions will allow us to understand and, where possible, overcome current AI instabilities. Editability: study algorithms that stealthily change a small number of parameters. This scenario is highly pertitent when new AI is built on top of third-party, foundation models. It also opens up the possibility of fixing errors on-the-fly without the need to re-train. Targetability: examine whether under-represented categories in the training data are more susceptible to adversarial attacks. This topic raises a key, and currently overlooked, issue in the ethical use of AI. Universality: develop linear, sparse, low rank mappings that create adversarial attacks. These new functions will expose novel, low-cost, threat mechanisms, but will also give insights into the decision boundary landscape. Roundability: use state-of-the art probabilistic rounding error analysis to justify large-scale, low precision computations. I will study (a) why current AI technologies appear to defy traditional worst-case floating point error bounds, and (b) whether low precision can be exploited by an adversary. Legislatability: devise easy-to-interpret results and practical case studies that can inform public opinion and impact the design of appropriate AI legislation. The project identifies high-profile open questions requiring tools from matrix analysis, optimization, backward error analysis, condition number theory and stochastic computation. Some of the proposed work is highly speculative and challenging, but will significantly advance our understanding of AI vulnerabilities.

Keywords: mathematical aspects of artificial intelligence
Unravelling the Effects of Music on Sleep through Musicology, Neuroscience, Psychology and Computer Science (Lullabyte)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands,Germany,Denmark,France,Spain,Sweden,Switzerland
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2022-11-01
End date: 2026-10-31
Duration (months): 48.0
Total project cost (EUR): 2580503.66
EU funding (EUR): 2468844.0
Participants: 22
Project status: SIGNED

Music exerts strong effects on the human brain, as evidenced by both subjective emotional reactions and overt changes in neurophysiology: lullabies are known in all cultures and times as an effective sleep aid for children and adults. Musicology focuses traditionally on musical structures and cultural practice, a mutual interaction with empirical neuroscience is yet missing. The Lullabyte project will for the first time bring leading researchers from musicology, sleep research, neuroscience and computer science together to fill this gap. Within the project, ten Doctoral Candidates will be trained in a radically interdisciplinary research field, and acquire profound skills relevant for industry and the cultural sector. Leveraging state-of-the-art neuroscience laboratories, big sleep datasets gathered with wearable technology, and data science strategies, the Doctoral Candidates will investigate the effects of music on the brain’s transition from wakefulness to sleep, from neurophysiological details of auditory processing in the thalamico-cortical system over changes in sleep structure induced by different kinds of music, to psychological and musicological analyses. Moreover, machine-learning strategies will help to algorithmically generate novel, neuroscience-deduced music with particularly strong somnogenic effects. Beyond hands-on training in these research projects with multiple secondments between the ten consortium partners, summer schools and satellite events with active participation of trainers from innovative industry partners and artists will teach Doctoral Candidates complementary skills in technology transfer, entrepreneurship, medical device regulation and public outreach. As a whole, Lullabyte will train a new generation of interdisciplinary researchers, and thus provide the fast growing market of personalized, algorithmically generated music with both a firm scientific basis and the personnel to strengthen Europe’s position in such technologies.

Keywords: sleep,lullabies,wearables,eeg,generative music,sonification
Single Atoms Immobilization on MXene-Metal-Organic Polyhedra Assemblies for Selective Reduction of CO2 to Formic Acid (SA-MXene-MOP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-12-01
End date: 2026-11-30
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

The EU has set a goal of achieving climate neutrality by 2050 and has implemented an ambitious plan to reduce greenhouse gas emissions, including CO2. The most eco-friendly solutions to tackle global energy and sustainability challenges are electrocatalytic (ECR) and photocatalytic (PCR) CO2 reduction into valuable products. Among the CO2 reduction products, formic acid (HCOOH) has diverse applications as a chemical feedstock, hydrogen storage material, methanol intermediate and fuel cell component. Despite advances in the field, there are still unresolved challenges related to slow electron kinetics, unfavourable product selectivity, and high operating cost. In this respect, single-atom catalysts (SACs) have unique performance due to maximum atom efficiency, unsaturated metal coordination, and the confinement effect, making them a promising solution. However, the efficiency and selectivity of SACs for ECR and PCR to HCOOH are still experimentally scarce. Therefore, tuning the electronic structure of SAC through their immobilization on 2D nanosheets is crucial for designing new catalysts. Accordingly, I plan to prepare novel non-noble metal SA-functionalized MXene-metal-organic polyhedral (MOP) assemblies to replace the state-of-the-art catalysts for efficient CO2 reduction to HCOOH. SA-MXenes can improve electron transport and CO2 capture during ECR and PCR. However, self-stacking of SA-MXene can limit electrolyte access and reduce active site utilization. MOP acts as a spacer to increase porosity and prevent restacking. SA-MXene-MOP, with ligands coordinated SA center will act as a photocatalyst. To ensure the successful implementation of project goals, I will conduct research at IEMN (CNRS & University of Lille) under Dr. Boukherroub's guidance. I expect the research findings will elicit noteworthy attention from academic laboratories across Europe and worldwide. This project will help me to enhance my academic profile, and establish a research group.

Keywords: single atom catalyst,mxene,metal organic polyhedra,electrocatalysis,photocatalysis,co2 reduction
Deconstructing Cell-Extracellular Matrix Co-Adaptive Mechanisms by Hydrogel Mechano-Actuation in Pathological Microenvironments (ECMAP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-02-01
End date: 2028-01-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Fibrosis, characterized by tissue stiffening and altered FAK signaling patterns, is highly prevalent in Europe and places a significant financial burden on our healthcare system. However effective treatments are hampered by the lack of accurate disease models. While most of our disease understanding comes from studying cells under static conditions, in vivo cell interactions are far from static, leading to inconsistencies between lab models, suggesting that tissue stiffness alone drives fibrosis, and clinical observations, indicating otherwise. The ECMAP project aims to bridge this gap in our knowledge by introducing a novel approach that replicates the dynamic processes driving fibrosis. Professor Fernandez's lab has recently discovered a molecular link between mechanical forces and FAK signaling at individual focal adhesions (IFAs), crucial in functional tissue-scale processes. This project will elucidate the role of increased FAK activity at IFAs during force transmission and mechanosensing in fibrosis progression. This will be achieved by combining molecular devices, light-activated ligands, and cutting-edge microscopy tools to monitor (fibrotic and healthy) FAK signaling in real-time while applying controlled forces at IFAs. This innovative platform for studying fibrosis progression at an unprecedented molecular resolution aims to facilitate drug discovery, enhance early diagnosis, and develop new tools for monitoring fibrosis and other tissue mechanics diseases. Our work represents a paradigm shift in treating mechano-diseases, aligning with urgent healthcare needs and offering hope for more targeted and effective solutions.

Keywords: mechanotransdunction,mechano actuating hydrogels,fibrosis,fak,focal adhesions,pnipam
Law, Economy and Seeing Woman’s Work: Knowledge Production and the ILO’s Domestic Workers Convention in Global Migration Governance (KnowingDOM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 1
Project status: CLOSED

This project will investigate how knowledge production takes place within the context of an international organization (IO) – the International Labour Organization (ILO). It will look into how what we know about domestic work has developed in the context of the establishment of the ILO’s Convention on Domestic Work (C189). The latter is a landmark global treaty that seeks to set employment standards and norms, for domestic workers. To date, C189 has only been ratified by 33 countries. The low ratification rate belies the demand for this kind of worker worldwide. This is an indicator of a ‘global care deficit’ and ‘crisis of social reproduction.’ This demand will not only increase in volume but also scope as the global population continues to age. The increasing complexity of these mobilities demand collective action and provision of global public goods. This project will examine how various actors engage with an international institution in making knowledge claims about domestic work. It will illustrate the contingency of these claims, to show that the process by which knowledge about domestic work is created is highly contentious - as actors compete over definition of terms, scope, jurisdiction, etc. By investigating how ‘science’, or the authoritative production of knowledge claims, informs politics and vice versa, this project aims to illustrate what Sheila Jasanoff calls civic epistemology: “the institutionalized practices by which members of a given society test and deploy knowledge claims used as a basis for making collective choices.” This project draws from the sociality of knowledge production in feminist interventions in science and technology studies that attend to different sources of epistemic authority, including voices ‘from below.’ The project will proceed in two stages: an analysis of the run-up to C189’s adoption and an investigation of how the ILO’s norm-setting activities diffuse to and from a regional organisation – the European Union.

Keywords: domestic work,international labour organization,domestic worker convention,feminist science studies
Bipyridines as Mediating Artificial Cofactors to replace NAD(P)H (BPYMAC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: SIGNED

In the quest for a sustainable and eco-friendly future, enzymatic catalysis has emerged as a pivotal platform, steering chemical synthesis towards environmentally benign pathways. The use of natural cofactors such as NADH (nicotinamide adenine dinucleotide, reduced) and NADPH (nicotinamide adenine dinucleotide phosphate, reduced) has been instrumental in these processes, providing essential reducing equivalents for numerous enzymatic transformations. In the production of valuable chemicals and pharmaceuticals via biocatalysis, NAD(P)H is utilized by various enzymes.NAD(P)H-dependent processes play a key role in pharmaceutical industry and the environment (reducing CO2 emissions), in the production of valuable fuels and chiral active pharmaceutical ingredients (APIs).While NAD(P)H is effective as a cofactor, it presents several issues that limit its practicality and sustainability – mainly due to high cost of cofactor, high process costs due to lack of recyclability and complex downstream processing. The central idea of BPYMAC is to leverage the advantages of bipyridines as ideal mediating artificial cofactors (MACs) to replace NAD(P)H due to their synthetic versatility, recyclability, tunability and stability. Synthetic strategies enable their conversion to redox polymer enabling their application as polymer films on electrodes, allowing their use in reactors with facile product separation. This will be the end goal of BPYMAC, meeting significant gaps in the state of the art. BPYMAC's research outcomes will help revolutionise bioelectrocatalyis by targeting synthesis of valuable products from CO2 reduction and production of chiral APIs in a reactor consisting of polymeric MAC and enzyme, optimised to produce products in high yield and with high stereoselectivity. These reactions will provide proof-of-concept for the potential of BPYMAC's tailored MACs as NAD(P)H replacements for reactions of interest for industry, society and the scientific community.

Keywords: nad p h replacements,enzyme catalysed reactions,bioelectrocatalysis,co2 reduction,chiral api synthesis
Bridging Organizations and marginalized communities for Local Sustainablity Transitions in EuRope (BOLSTER)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Cross-sectoral solutions for the climate transition
Action type: Research and Innovation actions
Countries involved: Netherlands,Spain,Poland,Portugal,Ireland,Bulgaria,Croatia,Belgium,Romania,Germany,Czechia,Australia
Call: Fostering a just transition in Europe (HORIZON-CL5-2021-D2-01, 2021)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 3792955.0
EU funding (EUR): 3792955.0
Participants: 13
Project status: SIGNED

No European should be put at a disadvantaged because of the European Green Deal (EGD). BOLSTER will deliver new scientific evidence on decarbonization transition strategies and how they intersect with various dimensions of inequality, such as gender, race, age and class. It will conceptualize the principle of leaving no one behind by developing participatory governance models and transition guidelines based on climate justice and gender equality. BOLSTER will launch action research in ten European regions. Seven of those regions are at high risk of being affected by the EGD, as they have a high concentration of carbon-intensive industries. The other three regions have already undergone an economic transition and will be studied in order to learn from the past. Research shows that transition policies predominantly benefit already privileged citizens and often tend to reproduce social inequalities. Moreover, there is a growing polarization vis-à-vis transition plans. The overall aim of this project is to understand how marginalized communities are affected by EGD-related policies and to see whether involving them in decision-making processes increases the support for transition plans. To achieve this goal, BOLSTER will use novel qualitative research methods with participatory approaches to improve the understanding of the experiences and needs of marginalized communities. Next, it will organize multi-actor forums with key actors in the regions. In order to enable balanced participation from all social groups, special attention will be paid to enhancing the capacities of organizations that represent marginalized groups. Moreover, BOLSTER will actively contribute to addressing procedural justice aspects in the transition process. The goal of the multi-actor forums is to increase support for the transition plans by better accommodating the needs of marginalized groups. We believe that BOLSTER’s activities will foster a more just transition.

Keywords: transition strategies participation marginalized communities climate justice qualitative research multi actor fora
Halophyte Biorefinery Process for Sustainable Production of Textiles, Composites, and High-Value Biochemicals (HALO-TEX)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Research and Innovation actions
Countries involved: Denmark,Netherlands,Belgium,Italy,Spain,Türkiye
Call: Circular design of bio-based processes and products (HORIZON-CL6-2024-CIRCBIO-02, 2024)
Start date: 2025-05-01
End date: 2029-04-30
Duration (months): 48.0
Total project cost (EUR): 3999685.0
EU funding (EUR): 3999685.0
Participants: 10
Project status: SIGNED

HALO-TEX demonstrates a novel, sustainable, and circular bioproduct manufacturing system based on the biorefinery of salt-tolerant plant biomass. Cellulose-based yarns and fabrics with improved recyclability, bio-based additives, and composites are targeted towards high-pressure textile and biochemical industries. It addresses the European Green Deal objectives, the EU Circular Economy Action Plan, and the EU strategies regarding bioeconomy and circular textiles, amongst other policies and initiatives. HALO-TEX goes beyond the state-of-the-art by using underexploited feedstock in an innovative extraction, pretreatment, and separation process cascade for maximum resource valorization, and sustainable cost-effective manufacturing of multiple products. Consumer acceptance studies and comprehensive product information systems will be developed to overcome the social barriers related to the uptake of bioproducts. The textile industry has a tremendous negative environmental impact regarding primary raw material, freshwater and land use, emissions and pollution, and waste generation. HALO-TEX addresses these issues by using novel, secondary feedstocks grown in marginal land, developing circular biorefinery system with low energy and chemical input, and enhancing the sorting and recycling of materials and bioproducts. It will provide an innovative value chain and a sustainable model for bioproduct manufacturing to advance transitions towards a circular bioeconomy, increase the uptake of novel products, and foster socio-economic opportunities, especially in rural, vulnerable regions. The partners are skilled experts within their respective fields, and the project builds on previous Horizon projects. Located across Europe, the consortium provides a broad perspective on the related research areas and target industries while ensuring that the results and project’s benefits are widespread, reaching consumers and stakeholders across the value chains and beyond sector borders.

Keywords: circular bioeconomy,biorefinery,secondary feedstocks,sustainable textiles,biomaterials,bioproducts
Artificial Neural Networks for the Prediction of Contrails and Aviation Induced Cloudiness (E-CONTRAIL)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (JU-JTI)
Countries involved: Spain,Belgium,Sweden
Call: Fundamental Science and Outreach for Aviation Green Deal (HORIZON-SESAR-2022-DES-ER-01, 2022)
Start date: 2023-06-01
End date: 2025-11-30
Duration (months): 30.0
Total project cost (EUR): 997500.0
EU funding (EUR): 997500.0
Participants: 4
Project status: SIGNED

Contrails and aviation-induced cloudiness effects on climate change show large uncertainties since they are subject to meteorological, regional, and seasonal variations. Indeed, under some specific circumstances, aircraft can generate anthropogenic cirrus with cooling. Thus, the need for research into contrails and aviation-induced cloudiness and its associated uncertainties to be considered in aviation climate mitigation actions becomes unquestionable. We will blend cutting-edge AI techniques (deep learning) and climate science with application to the aviation domain, aiming at closing (at least partially) de existing gap in terms of understanding aviation-induced climate impact. The overall purpose of E-CONTRAIL project is to develop artificial neural networks (leveraging remote sensing detection methods) for the prediction of the climate impact derived from contrails and aviation-induced cloudiness, contributing, thus, to a better understanding of the non-CO2 impact of aviation on global warming and reducing their associated uncertainties as essential steps towards green aviation. Specifically, the objectives of E-CONTRAIL are: O-1 to develop remote sensing algorithms for the detection of contrails and aviation-induced cloudiness. O-2 to quantify the radiative forcing of ice clouds based on remote sensing and radiative transfer methods. O-3 to use of deep learning architectures to generate AI models capable of predicting the radiative forcing of contrails based on data-archive numerical weather forecasts and historical traffic O-4 to assess the climate impact and develop a visualization tool in a dashboard Upon successful achievement of the objectives described above, we ambition to provide aviation stakeholders with an early and accurate (thus, reducing the associated uncertainty) prediction of those volumes of airspace with the conditions for large global warming impact due to contrails and aviation-induced cloudiness.

Keywords: climate change artificial intelligence remote sensing deep learning