Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
BOOSTER PACKAGING FOR EUROPE (Pack4EU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Coordination and support actions
Partnership: CHIPS (JU-JTI)
Countries involved: France,Germany,Netherlands,Portugal,Austria,Romania,Italy,Denmark,Spain,Finland,Belgium,United States,Hungary
Call: Pan-European network for Advanced Packaging made in Europe (CSA) (HORIZON-KDT-JU-2023-3-CSA-IA, 2023)
Start date: 2023-07-01
End date: 2024-06-30
Duration (months): 12.0
Total project cost (EUR): 999905.0
EU funding (EUR): 999030.0
Participants: 50
Project status: CLOSED

Pack4EU’s objectives are (1) the creation of the “Pan European network on advanced semiconductor packaging”, and (2) give guidance and deliver the awaited urgent results through policy recommendations, the “Advanced Semiconductor Packaging Master Plan for Europe”, addressing investments, pilot lines, competence centers and further coordination actions dedicated to semiconductor packaging and the EU green deal. This will be worked on by a consortium gathering all the industry associations including the scientific ones supported by 40 associated partners all along the value chain. This group will first create a European definition of advanced semiconductor packaging illustrated by visuals and glossary. The tasks are: build the “who’s who” of advanced semiconductor packaging, involve SMEs, Start-ups and Scale-ups, RTOs; map the entire supply chain from design, materials, equipment, fabs, and all the way to test and reliability; engage with MS, Regions and the specific agencies to consolidate the policies; study the other Chips Acts deployed in non-member countries and assess the existing European position in the global packaging world, for the most pertinent European needs and applications; aggregate the recent past similar actions at national or regional clusters level; engage with world leading OSATs and European stakeholders to reconsider manufacturing in Europe; assess the gaps in education and skills required for human resources geared towards advanced packaging and citizen’s awareness. Objectives for guidance also include the Chips-packaging diplomacy, autonomy but no isolation, partnering with competencies from all over the world, vulnerability and sovereignty issues, for a decade long vision and a resilient European industrial infrastructure, making it possible to create local economic strengths, to create local jobs and to maintain and reinforce local advanced know-how and expertise in the long run while reinforcing European leadership in the race to

Keywords: the advanced packaging master plan for europe
Attractive Research Ecosystem in the Adria Region in the Field of Personalised Preventive Healthcare (AttractAdria)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Reforming and enhancing the European R&I System
Destination: Reforming and enhancing the European R&I System
Action type: Coordination and support actions
Countries involved: Bosnia and Herzegovina,Ireland,Norway,Croatia
Call: Talent ecosystems for attractive early research careers – pilot (HORIZON-WIDERA-2024-ERA-02, 2024)
Start date: 2025-09-01
End date: 2028-08-31
Duration (months): 36.0
Total project cost (EUR): 2192727.5
EU funding (EUR): 2192727.5
Participants: 15
Project status: SIGNED

AttractAdria will create an attractive ecosystem to improve access to excellence at the universities in BiH by raising the research profile of the institution and its staff in the field of personalised healthcare via targeted networking and mentoring and training activities with internationally leading research institutions. By networking activities with global leaders, the potential of the BiH universities will be developed to become European-wide known centres with increasing R&I contributions and achievements. During the AttractAdria, Ministry of Civil Affairs, Ministry of Science and Higher Education of Kanton Sarajevo, HNK Government and SERDA in BiH and the National Science Foundation in Croatia will pilot some novel measures for R&D. The AttractAdria project will help to increase the scientific level, research quality, international visibility, and competitiveness of the BiH universities through targeted activities aimed at career development, transfer of knowledge, institutional development, exchange of best practices and networking. Cumulatively, this will improve integration of researchers from Croatia and BiH in the European Research Area and increase their participation in international projects.

Keywords: attractive research,personalised preventive healthcare,adria region
3-dimensional Organization and Functions of Translation in Organelle Proximity (3DTOP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cell Biology, Development, Stem Cells and R egeneration
Panel description: For all organisms : Structure and function of the cell, cell -cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1999838.0
EU funding (EUR): 1999838.0
Participants: 1
Project status: SIGNED

In eukaryotic cells, many proteins are produced next to the organelles where they function, demonstrating a link between translation and protein targeting. The mechanisms of this connection are mostly unknown. In this proposal, I bring together the fields of translation regulation and organelle biogenesis to find this out. I approach the problem with a powerful combination of functional genomics and cryogenic electron tomography (cryo-ET). First, I want to create a quantitative map of proximal translation next to all the organelles and their sub-domains. Using high-throughput imaging, I will determine localizations of all the mRNAs and their dependence on translation. I will also map the positions and orientations of ribosomes next to all the membranes using proximity labelling and direct quantification of native ribosomes with cryo-ET. Beyond mapping, I want to understand how this local translation map is adapted to different conditions. Using high-throughput screening, I will determine what global and local factors establish and regulate proximal translation at each organelle. Finally, I will investigate the role proximal translation plays in essential organelle functions and get mechanistic insights into how local regulators help to carry it out. When completed, the project will overturn the binary view of either Sec61-coupled translation on the ER surface vs. free cytosolic translation of all the other organellar proteins. Instead, I will uncover a holistic picture of multiple proximal translation locales with distinct regulation. I aim to discover new connections between the two fundamental processes of protein synthesis and organelle biogenesis and thus make a ground-breaking advance in the understanding of how cells coordinate their architecture and functions.

Keywords: protein targeting,protein translocation,mitochondria,endoplasmic reticulum,peroxisomes,ribosome,ribosome quality control,regulation of translation,local translation,yeast genetics,high content screening,cryogenic electron tomography,subtomogram averaging
CANCER PREVENTION AMONG INDIVIDUALS WITH MENTAL ILL-HEALTH: CO-ADAPTING AND IMPLEMENTING PATIENT NAVIGATION FOR PRIMARY CANCER PREVENTION (CO-CAPTAIN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Cancer
Destination: Cancer
Action type: Research and Innovation actions
Countries involved: Austria,Greece,Spain,Netherlands,Poland,Belgium
Call: Improving and upscaling primary prevention of cancer through implementation research (HORIZON-MISS-2022-CANCER-01, 2022)
Start date: 2023-06-01
End date: 2026-05-31
Duration (months): 36.0
Total project cost (EUR): 2576493.75
EU funding (EUR): 2526618.75
Participants: 14
Project status: SIGNED

Cancer and mental ill-health constitute leading public health problems in Europe, with more than 80 million people reporting mental health issues in Europe and around 4 million new cases of cancer diagnosed per year. People with mental ill-health, have higher cancer incidence and reported mortality, an excess linked to risky health behaviours as well as significant barriers experienced when accessing the often highly fragmented health care systems. Timely and evidence-based preventive strategies including optimizing health care pathways provide a solution to the high cancer morbidity and could improve overall health outcomes in this disadvantaged population. The aim of the Co-CAPTAIN project is to deliver an innovative solution based on the Patient Navigation Model. The Patient Navigation Model is an evidence-based patient-centred intervention which supports patient empowerment through removal of systemic barriers, providing social support and promoting timely access to primary prevention services. Co-CAPTAIN includes partner organizations with long-standing experience in the field of health and social care for people with mental ill-health in the south, east, northwest and central Europe, as well as academic institutions and local governments. Based on implementation science know-how and using the Consolidated Framework for Implementation as well as the Research and the Reach, Effectiveness, Adoption, Implementation and Maintenance frameworks, the Co-CAPTAIN project aims to reduce the gap in health inequalities for people with mental ill-health by reducing cancer burden and improving overall health, which will, in turn, reduce associated costs across health and social care systems in Europe. Moreover, the Co-CAPTAIN project aims to harness the transformative potential of the integrated care pathways in cancer as well as provide health and social care policy recommendations for the adoption and implementation of the Patient Navigation Model across Europe. This action is part of the Cancer Mission cluster of projects on ‘Prevention and early detection’.

Keywords: cancer prevention health inequalities mental health physical activity nutritional
Unlocking the full potential of renewable energy with the Ocean Battery (OCEANBATTERY)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2023-07-01
End date: 2025-06-30
Duration (months): 24.0
Total project cost (EUR): 4434373.75
EU funding (EUR): 2499999.0
Participants: 3
Project status: SIGNED

The Ocean Battery is a CES Best-of-Innovation Award winning breakthrough solution based on proprietary Key Enabling Technology to solve the huge challenge of balancing supply & demand for the global offshore e-Power industry due to intermittent production of wind power. Our patented and sustainably produced Ocean Battery system substantially lowers the CAPEX for the massively expensive offshore power grid, generating a very high ROI for the unique Ocean Battery. Soon, weather conditions dictate the timing of renewable energy production, causing large fluctuations. Oversupply, resulting in negative energy prices and even blackouts create a market in excess of € 200 bn for energy storage. This project demonstrates the Ocean Battery in a lake: a full-scale operational system to show and validate the operation, installation, and maintenance processes. After that, the solution is ready to scale offshore and support the energy transition by providing GWh-scale ecofriendly energy storage.

Keywords: scalable energy storage,utility scale energy storage,renewable energy sources,offshore energy storage,offshore wind energy,floating solar energy,marine energy
Comprehensive Technology to Improve Energy Efficiency and Operation Safety of High-speed Freight Trains (TEESFtrain)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-16
End date: 2027-01-15
Duration (months): 18.0
Total project cost (EUR): 157112.46
EU funding (EUR): 157112.46
Participants: 1
Project status: SIGNED

For increasing the amount of freight transported by railway, freight trains have become longer and faster in recent years. The rising speed brings large motion resistances, including wheel-rail contact forces, suspension forces, and wind forces. On one hand, larger motion resistances consume more energy, producing more carbon emissions. On the other hand, violent wheel-rail forces and wind forces lead to high risks of derailment and overturning for high-speed freight trains (HSFTs). To save energy consumed by motion resistances (ECMR), some scholars reduced wind drag forces on HSFT by adjusting the train composition, and some scholars regarded HSFT as a mass point to optimize switching points of accelerating, cruising, coast, and braking based on empirical equations of ECMR. Previous studies did not evaluate the complete ECMR of the wind-vehicle-track coupled system precisely, not to mention juggling ECMR and operation safety of HSFT. Thus, this project adjusts motion resistances of HSFT by optimizing its structural parameters and control strategy to simultaneously decrease ECMR and improve operation safety, thereby reducing induced carbon emissions safely. This project will establish the ECMR model for trains under wind actions. On this base, the train configuration and cargo loading position will be optimized for energy efficiency and operation safety. The operation condition of HSFT will be adjusted according to track conditions to reduce ECMR. Finally, a semi-active control strategy of suspension dampers will be proposed to decrease ECMR and carbody vibration. This project can provide an effective tool to evaluate ECMR and take comprehensive measures to realize multi-objective optimization for energy efficiency and operation safety. If widely applied within the EU, the research outcomes can save €1.3 billion and decrease 0.3 million metric tons of carbon emissions annually. This project will greatly support the EU’s blueprint for climate neutrality by 2050.

Keywords: vehicle system dynamics railway engineering train aerodynamics multi objective optimization energy efficiency multibody dynamics simulation
Investigating lipid-associated macrophage (LAM) biology and functions in chronic fibrosis (LAMs4LIFE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 216240.0
EU funding (EUR): 216240.0
Participants: 1
Project status: SIGNED

Macrophages are innate immune cells present in almost every organ of the body. While previously considered to be a homogenous population, thanks to recent advances in single cell technologies, it is clear that each tissue harbours multiple distinct populations of macrophages especially in the context of tissue injury and inflammation. One subset of macrophages that has gained attention recently are the lipid-associated macrophages (LAMs). Originally described in obese adipose tissue, macrophages with very similar phenotypes have since been described across a range of diseased tissues in both the mouse and human. The widespread presence of LAMs across many important human diseases, makes them an attractive target for future therapeutic strategies with the potential to improve patient health. However, despite this potential, our understanding of the biology and functionality of LAMs remains in its infancy. Therefore, I hypothesize that gaining a more in-depth understanding of LAMs will enable the design of novel therapeutic approaches which could benefit numerous patients. Thus, this project aims to further our understanding of LAM biology and functionality. We will focus this project on the context of chronic fibrosis of the liver and lung, as fibrosis is a common feature of many diseases and LAMs have been identified in this setting both in the mouse and human.

Keywords: liver,lung,lipid associated macrophages,fibrosis
Science from the large scale cosmic microwave background polarization structure (SCIPOL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: France
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 1998750.0
EU funding (EUR): 1998750.0
Participants: 1
Project status: SIGNED

Observational cosmology is moving towards its next major milestone: high-precision measurements of the cosmic microwave background polarization with the goal of detecting and characterizing the primordial B-modes. These polarization patterns would provide a unique picture of the early Universe, shedding the light on the conditions at that time, be it cosmic inflation, gauge fields, or more exotic possibilities. In a regime of energy where standard models are expected to break, such observations could revolutionize our current picture of cosmology and high energy physics. Characterizing such signal requires (1) reaching extremely low instrumental sensitivity levels and (2) controlling instrumental and astrophysical systematic effects with unprecedented fidelity. While (1) is about to be reached with the planned deployment of funded, cutting-edge observatories such as the Simons Array/Observatory, CMB-S4 and LiteBIRD, (2) is already limiting the current constraints and will be studied and uniquely mitigated by SciPol. My project is an opportunity to claim a leadership role for Europe in one of the most active and impactful research areas in physics, complementing the hardware efforts led by the US and Japan. I will: - construct accurate, open-source and versatile models for the instrumental, astrophysical signals and noise properties; - develop and exploit new, general algorithms adjusting previous models from observations, and producing a unique set of instrument- and foreground-corrected maps; - make a statistically robust cosmological inference of these, especially on the large scale, implementing a gravitational lensing correction. I have been at the forefront of this research for the last 10 years, made key contributions to the analysis and scientific exploitation of the POLARBEAR data sets, and to preparations and scientific optimization of the forthcoming efforts. I am consequently uniquely positioned to deliver the objectives of the proposed work.

Keywords: cosmic microwave background,inflation,early universe
Holistic Approach towards Empowerment of the DiGitalization of the Energy Ecosystem through adoption of IoT solutions (HEDGE-IoT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Luxembourg,Germany,Greece,Portugal,Netherlands,Finland,France,Belgium,Croatia,Romania,Ireland,Italy,Slovenia
Call: Supporting the green and digital transformation of the energy ecosystem and enhancing its resilience through the development and piloting of AI-IoT Edge-cloud and platform solutions (HORIZON-CL5-2023-D3-01, 2023)
Start date: 2024-01-01
End date: 2027-06-30
Duration (months): 42.0
Total project cost (EUR): 21859157.91
EU funding (EUR): 17999755.0
Participants: 47
Project status: SIGNED

HEDGE-IoT proposes a novel Digital Framework which aims to deploy IoT assets at different levels of the energy system (from behind-the-meter, up to the TSO level), to add intelligence to the edge and cloud layers through advanced AI/ML tools and to bridge the cloud/edge continuum introducing federated applications governed by advanced computational orchestration solutions. The HEDGE-IoT Framework will upgrade the RES-hosting capacity of the energy systems and will unleash a previously untapped flexibility potential. It will increase the resilience of the grid, create new market opportunities and promote advances in IoT standardization, by introducing and managing a plethora of diversified, interoperable energy services over scalable and highly distributed data platforms and infrastructure. The multi-dimensional framework of HEDGE-IoT comprises the following pillars: (a) the Technology Facilitator Pillar will exploit the computational sharing by offloading applications on the grid edge, towards providing a set AI/ML federated learning and swarm computing applications; (b) the Interoperability Pillar, which leverages on leading-edge interoperable architectures, such as the Data Space architectures; (c) the Standardisation Pillar will enable all involved platforms, systems, tools and actors to seamlessly communicate and exchange data in standardized formats using widely used standards, such as SAREF, etc.; (d) the Digital Energy Ecosystem Enabling Pillar will ensure the creation of an ecosystem facilitating the increased integration of RES and characterised by resilience. Liaisons with EU initiatives for IoT and digitalisation will be established (e.g., the AIOTI) and the engagement of stakeholders will be ensured by addressing IoT ethics and cultivating trust among end-users, thus promoting inclusivity. Scalability and replicability studies will be performed and connections with innovators and SMEs will be established through the Open Call mechanism of the project.

Keywords: ai ml,internet of things,saref,data space,edge processing,digitalization of power system