Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Maltese-European Linkages for Internationalisation, Innovation and Technology Transfer 2 [Innovation services] (MELIITA 2)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Malta
Call: H2020 2D CONSULTATION EEN (H2020-EEN-SGA2-2017-2018, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 33312.5
EU funding (EUR): 33312.5
Participants: 5
Project status: CLOSED

This proposal addresses the growth-oriented business support services that will result in improved competitiveness and access to markets for EU enterprise. These services are as stipulated by the H2020 Consultation call for EEN H2020 services recently issued by the European Commission and will be implemented throughout 2017-2018 by the Network's consortium in Malta, in full synergy and complementarity with the other work packages supported by the relevant and concurrent COSME call for Enterprise Europe Network services. The objective behind the MELIITA 2 proposal is to support the smart growth of the Maltese SMEs by increasing the efficiency and effectiveness of investments in research, development and innovation and to contribute to a better and more efficient connection of stakeholders and players along the innovation chain. By combining the actions under this H2020 programme with the support being offered under COSME, the Network will be best positioned to offer both business and innovation support along the entire value chain. Services are thus being provided to clients in the wider contest of, and in line with, the Europe 2020 strategy. The MELIITA 2 proposal namely aims to: • Enhance innovation management capacity, thus rendering more efficient the full innovation process of Micro and SMEs, irrelevant of benefitting from the SME Instrument, and to help potentially good ideas effectively reach the market. • Strengthen innovation capacity and to ensure Maltese beneficiaries of the SME Instrument receive the most appropriate support services based on identified weaknesses in their innovation capacities and so encourage the successful exploitation of their innovation project and to induce sustainable growth beyond the programme period, and most importantly, • Create a more innovative, competitive business community.

Keywords: innovation management,smei,growth
Comprehensive allergen detection using synthetic DNA libraries (AllergenDetect)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Israel
Call: ERC Proof of Concept Grant (ERC-2018-PoC, 2018)
Start date: 2019-05-01
End date: 2020-10-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Over the last 50 years, allergies have become a major health issue affecting approximately 20% of adults and more than 30% of children in developed countries. Allergies impair the life quality of affected individuals and diagnosis/treatment is costly for health care systems. In the EU, the avoidable indirect costs of patients insufficiently treated for allergy is estimated to range between 55 and 151 billion Euro per year. A key issue towards fighting this allergy epidemic lies in the diagnosis of allergies, which is still limited by expensive, low throughput methods allowing to test only a few dozens of allergens at once. Yet, several thousands of allergens have been reported in the literature and cost effective methods for testing hundreds or even thousands of allergens are highly sought after. Here, we propose a novel high throughput method (AllergenDetect) enabling to test more than 3000 protein allergens in parallel within a single test, relying on our ERC-funded technology. Instead of cumbersomely purifying protein allergens from natural sources, we will apply synthetic DNA libraries to produce allergens using expression systems commonly applied in biotechnology. Our method greatly expands the throughput of allergen testing compared to state of the art methods and allows for the first time to systematically test all known protein allergens at a fraction of today’s cost and within a single assay. In the first phase, we plan to market this technology as diagnostic kits to hospitals and analytic laboratories that have the required infrastructure already in place. For patient samples from private practitioners, specialized allergists, and individuals seeking allergy testing on their own, we are planning to launch a spin-off laboratory directly performing these AllergenDetect tests.

Keywords: allergies,allergy epidemic,allergens,molecular diagnostics,synthetic dna library,high throughput assay,phage display,antibodies,antibody detection,machine learning
Next generation precision antibody profiling - from science fiction to reality (TopSpec)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Germany,Switzerland,Greece,Sweden,France,Netherlands,United Kingdom
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2018)
Start date: 2019-01-01
End date: 2022-12-31
Duration (months): 48.0
Total project cost (EUR): 3991500.0
EU funding (EUR): 3991500.0
Participants: 8
Project status: CLOSED

One of the major challenges of modern medicine is to understand how the human organism defends itself against invasions and diseases. The biggest mystery is the human immune system, and understanding this ultimately requires knowledge of the sequence repertoire of human antibodies and their respective antigens. The purpose of the TopSpec project is to be the first in the world to solve this challenge, opening up opportunities in medical research and drug development that are today only dreamt about. We will create a breakthrough technology that will revolutionize academic, clinical and industrial proteomics and dramatically advance the development of new generation antibody- and protein-based therapeutics. Antibodies represent the most sophisticated line of natural defense against disease. Knowing exactly which antibodies are produced in response to a particular disease enables us not only to better understand the cause of the disease but also to provide new-generation cures in the form of personalized therapeutic antibodies. The limiting factor for this to truly be achieved is to find a way to analyze and sequence large molecules in the gas phase, and this represents a formidable challenge. The TopSpec project will develop ground-breaking TOP-down tandem mass SPECtrometry (MS/MS) approaches based on novel radical gas-phase ion-electron and ion-atom reactions, and implement them on a unique, hyphenated, ultrahigh-resolution MS platform. Another “killer innovation” is the ability to greatly simplify MS/MS spectra of large molecules by adding another dimension of separation – collisional cross-sections of fragment ions using two parallel approaches. TopSpec will be the first project to implement de-convolution of massively overlapping isotopic clusters, solving one of the greatest challenges in top-down MS of large molecules.

Keywords: antibody profiling,immunotherapeutics,mass spectrometry,tandem mass spectrometry
Alpine Community Economies Lab: Bringing together multi-level stakeholders to co-produce sustainable alpine futures in the light of economic globalisation and climate change (ACElab)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-04-01
End date: 2021-12-10
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

Alpine Community Economies Lab (ACElab) uses participatory design methods to support alpine communities in addressing cross-cutting concerns of sustainable socio-economic development outlined in the EU Strategy for the Alpine Region and the Alpine Convention. Via a gender-sensitive community-based research space, I will engage a diversity of civic actors and policy makers in the collaborative investigation of (trans)local economies (e.g. forestry, tourism, crafts) sustaining their valley district. Together we will envision developments that have both people and the environment at their core. To do so, I mobilise my expertise in design-led civic participation and feminist economic geography and my Host and Secondment institutions’ expertise in regional development and participatory governance. Together we will prototype, test and refine a multifaceted community economies toolkit to be released via open-access. ACElab will enhance my expertise in leading participatory research projects with a gender-sensitive approach that work across the public and private sector. Through collaborations with the Host, the Secondment institution and the partnering policy makers (from local to European level), I will gain significant skills in research governance, public engagement and impact creation. I will gain expertise on alpine regional development and build research networks for follow-on grants. Thus, the fellowship will support my intended career of leading a participatory research lab in the alpine region. Beyond myself, ACElab offers significant value in the context of Horizon 2020 by addressing areas of special focus (e.g. economic growth & innovation, inclusive & reflective societies) and key objectives (e.g. build an effective research and innovation system, increase the economic potential of strategic areas) in collaboration with policy makers. Its value is significant for the Host as it premiers a community-based research lab and working with design-led methods.

Keywords: participatory design,community based research lab,feminist economic geography,co produced regional development,gender sensitive methods
Photonics sensing platform for process optimisation in the oil industry (Hydroptics)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Partnership: Photonics (cPPP)
Countries involved: Austria,Austria,Greece,Türkiye,Belgium,Switzerland,Greece,Switzerland
Call: Application driven Photonics components (H2020-ICT-2019-2, 2019)
Start date: 2019-12-01
End date: 2023-11-30
Duration (months): 48.0
Total project cost (EUR): 7740043.75
EU funding (EUR): 6222456.25
Participants: 11
Project status: SIGNED

HYDROPTICS will develop a set of integrated sensors, making use of advanced photonics subsystems, aimed at optimising the processes of the oil industry. The device will be validated in real industrial settings, for oil extraction and oil refining processes. The HYDROPTICS platform will perform: 1) oil in water measurements, 2) corrosion inhibitor concentration measurements, 3) oil droplets and suspended solids in water measurements, 4) industrial process optimisation, based on simulation of processes through digital twins, as well as data assimilation from the readings coming from the sensors. HYDROPTICS makes use of cutting edge photonics in order to perform the above tasks: a) Quantum Cascade Laser Frequency Combs spectroscopy, for ultra fast and sensing of oil in water concentration. b) Quantum Cascade Laser ATR spectroscopy, using MCM surface ATR crystals, for ultra-sensitive sensing of corrosion inhibitors in water. c) High resolution spectral and spatial resolution hyperspectral imaging, for particle classification in aqueous suspensions. The final HYDROPTICS platform will be tested in both upstream (oil extraction) and downstream (oil processing) industrial processes, in order to validate the sensors, and fine-tune the algorithms that regard process optimisation of said industrial processes.

Keywords: mid infrared,frequency combs,oil industry
The Invention of Cultural Diplomacy: cooperation and transnational competition in European and transatlantic international relations 1870-1940 (INVCULTURALDIPLO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-03-01
End date: 2024-06-21
Duration (months): 24.0
Total project cost (EUR): 184707.84
EU funding (EUR): 184707.84
Participants: 1
Project status: SIGNED

Cultural diplomacy has gained extraordinary significance in European international relations since the end of the nineteenth century as countries faced challenges in their Empire and as military force on foreign soil became increasingly contested. This project examines the making of this new aspect of foreign policy from the late nineteenth century until the beginning of the Second World War, with a focus on three case studies: Britain, France and Germany. The US will also be analysed as a battled ground for the cultural diplomacies of these western European countries. Employing an interdisciplinary approach – drawing on diplomatic and political history, cultural studies, transnationalism and textual analysis, the project will examine a broad range of private and diplomatic documents, as well as published pamphlets and media sources. The project’s first objective is to evaluate why European countries turned to foreign cultural policies as a new element of their diplomacy. Secondly it aims to reassess the chronology of the rise of cultural diplomacy, which the historiography conventionally sets to the 1920s (when cultural diplomatic bureaux opened in European foreign offices). Thirdly the project aims to renew our understanding of the policy making practices in this domain. These objectives will be met by transcending bi-national approaches that dominate the historiography of cultural diplomacy to assess the influence of entangled national competitions and asymmetric ways in which France, Germany and Britain conceptualised the significance of culture for their European and transatlantic diplomacies. Building upon theories of new diplomatic history that have stressed the significance of non-state actors, this research also goes beyond Foreign Office-centred approaches to examine the role of civil society individuals (including emigrants and transnational networks of private citizens), in shaping this area of diplomacy.

Keywords: history of international relations,european history,history of soft power,transnationalism
PORTable Innovation Open Network for Efficiency and Emissions Reduction Solutions (PIONEERS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Innovation actions
Countries involved: Italy,Germany,Germany,Spain,Germany,Germany,Spain,Belgium,Belgium,China,Switzerland,Belgium,Belgium,Belgium,Romania,Romania,Belgium,Belgium,Greece,France,Netherlands,Netherlands,Netherlands,Netherlands,Netherlands,Netherlands,Netherlands,Netherlands,Portugal,Canada,United Kingdom
Call: Green airports and ports as multimodal hubs for sustainable and smart mobility (H2020-LC-GD-2020-1, 2020)
Start date: 2021-10-01
End date: 2026-09-30
Duration (months): 60.0
Total project cost (EUR): 33465726.63
EU funding (EUR): 24999997.259999998
Participants: 57
Project status: SIGNED

PIONEERS brings together four ports with different characteristics, but shared commitments towards meeting the Green Deal goals and Blue Growth socio-economic aims, in order to address the challenge for European ports of reducing GHG emissions while remaining competitive. In order to achieve these ambitions, the Ports of Antwerp, Barcelona, Venlo and Constanta will implement green port innovation demonstrations across four main pillars: clean energy production and supply, sustainable port design, modal shift and flows optimization, and digital transformation. Actions include: renewable energy generation and deployment of electric, hydrogen and methanol vehicles; building and heating networks retrofit for energy efficiency and implementation of circular economy approaches in infrastructure works; together with deployment of digital platforms (utilising AI and 5G technologies) to promote modal shift of passengers and freight, ensure optimised vehicle, vessel and container movements and allocations, and facilitate vehicle automation. These demonstrations form integrated packages aligned with other linked activities of the ports and their neighbouring city communities. Forming an Open Innovation Network for exchange, the ports, technology and support partners will progress through project phases of innovation demonstration, scale-up and co-transferability. Rigorous innovation and transfer processes will address technology evaluation and business case development for exploitation, as well as creating the institutional, regulatory and financial frameworks for green ports to flourish from technical innovation pilots to widespread solutions. These processes will inform and be undertaken in parallel with masterplan development and refinement, providing a Master Plan and roadmap for energy transition at the PIONEERS ports, and handbook to guide green port planning and implementation for different typologies of ports across Europe.
Exploring Matter with Precision Charm and Beauty Production Measurements in Heavy Nuclei Collisions at LHCb (EXPLORINGMATTER)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Italy,France
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-04-01
End date: 2021-12-31
Duration (months): 81.0
Total project cost (EUR): 1849957.0
EU funding (EUR): 967006.04
Participants: 2
Project status: CLOSED

Collisions of ultra relativistic nuclei are a tool to reach huge energy densities and to form a new state of matter called Quark-Gluon Plasma (QGP), where quarks and gluons can move freely. A number of experiments have studied the possible formation of QGP, but the behaviour of heavy particles such as charm (c) and beauty (b) quarks when they traverse this medium is largely unknown and is the most powerful tool to prove the creation of the QGP and to characterise it. I will perform novel measurements using the LHCb detector at CERN, which covers an unique kinematic region, essential for a full understanding of QGP and nuclear matter in general. LHCb has been optimised to perform c and b quark physics measurements in proton-proton collisions. In EXPLORINGMATTER I propose to extend the LHCb programme to collect for the first time data in heavy ion collisions. Three experimental scenarios are foreseen: (1) Collisions of protons, benchmark to understand the behaviour of the c and b particles in other more complicated environments, as well as providing the final answers to the mechanism of heavy quarkonium production;(2) Collisions of protons with heavy nuclei, where cold nuclear matter effects in high-energy collisions can be studied in detail to understand lead nuclei collisions, where QGP is expected to be formed. (3) Collisions of heavy nuclei, pursued (a) by analysing heavy nuclei interactions through a dedicated setup in which gas will be injected in the LHCb interaction region, reaching energy densities typical of dedicated fixed target experiments; (b) by collecting heavy ion collision data at the LHC. This second setup, which has not been envisaged by LHCb up to now will revolutionise the measurements in this area thanks to the LHCb coverage and precision not achievable by any other experiment. My measurements will furthermore indicate the route to new experiments that could be designed on the basis of these findings.

Keywords: heavy nuclei,quark gluon plasma,quarkonia
Critical Transitions in Complex Systems (CRITICS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: Germany,Germany,Spain,Ireland,Netherlands,Netherlands,Denmark,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-04-01
End date: 2019-03-31
Duration (months): 48.0
Total project cost (EUR): 3896688.1
EU funding (EUR): 3896688.1
Participants: 10
Project status: CLOSED

Complex systems research has been on the forefront of scientific priorities of many national research councils and the EU for more than a decade. Many very interesting phenomena have been identified and explored, but the development of the underpinning mathematical theory has been lagging behind. The proposed training network builds on an emerging development in applied mathematics to provide proper mathematical theory for the existence of early-warning signals for sudden changes in dynamical behaviour, so-called critical transitions, which have been reported by applied scientists in various contexts. Practical implications for the existence of such early-warning signals are far reaching, since these would enable the development of better control strategies to avoid or diminish the effect of catastrophes. Topical examples include epileptic seizures, stock market collapses, earthquakes, and climate. Attending to the mathematical underpinning for critical transitions in complex systems, it is apparent that the relevant mathematical discipline of bifurcation theory, that has been developed to great acclaim and use for primarily low-dimensional deterministic autonomous (i.e. intrinsically time-independent) dynamical systems, and (in the context of phase transitions) for material science, does not apply without nontrivial modification to most of the complex systems contexts. The training network is a response to the needs of applied scientists (including many in the private sector) for a proper mathematical underpinning of early-warning signals. After their training, the trained researchers will be at the very forefront of this rapidly developing field, with many practical skills and crucial theoretical insights into the possibilities (and impossibilities) of early-warning signals for critical transitions in a wide range of contexts.

Keywords: complex systems,critical transitions,early warning signals,tipping points,bifurcations,networks