Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
CIVICITI: THE CITIZEN PARTICIPATION PLATFORM (civiciti)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-09-01
End date: 2019-02-28
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Plataforma Civiciti, S.L. (from now on Plataforma Civiciti) is an ICT company specialized in participatory democracy tools whose aim is to globally commercialise its main product: CIVICITI. CIVICITI is a neutral and independent participation platform created to help public administrations, organisations, businesses and the overall citizenship to discover, discuss and take decisions about their issues of concern. It is therefore a two-way interaction platform between various actors interested in a common issue. The company’s main mission is to reinforce participatory digital democracy, enriching the relationship between the citizenship and the public administration. Its vision is to be the global standard for digital participatory democracy. Based on a SaaS environment and using patented e-voting technology , CIVICITI is able to provide disruptive solutions to public institutions regardless of their size. At it is stated in the reflection paper on the social dimension of Europe : “Building confidence and trust is essential for progress, modernisation and openness to change”. CIVICITI responds to the global need and concern of building trust and promoting engagement between the citizenship and the public sector. The platform aims to close the existing and increasing gap between these two actors. For this reason, CIVICITI offers an affordable, scalable, customizable, user-friendly and ready to use platform, thus allowing citizens to easily participate in the decision-making processes and helping the public administrations to take better decisions for all’s profit. Therefore, thanks to CIVICITI, public authorities and other actors are able to better communicate about their policies and/or concrete projects, receive feedback and carry out secure and binding voting processes.

Keywords: e participation,democracy,platform
A novel muscle disorders 3D in vitro system for drug screening and validation. (MUSCLEGUY)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Portugal
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-10-01
End date: 2018-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

MUSCLEGUY represents a unique opportunity to commercialize a novel 3D in vitro system for screening and validation of drug candidates to treat muscle disorders. Although skeletal muscle disorders are relatively rare they pose a huge socioeconomic burden. Currently there is a lack of therapeutic options for the majority of patients. This is, for an important part, due to the lack of reliable, reproducible, and physiological relevant in vitro models of muscle disorders that accurately reflect the in vivo reality on which novel therapeutic strategies may be developed. We generated a novel 3D in vitro system of highly matured myofibers, the relevant functional unit of the muscle affected in most muscle disorders and used it to identify novel therapeutic targets of muscle disorders. During MUSCLEGUY, we will further technically optimise our in vitro system to generate human relevant disease models for muscle disorder. Such systems can be used for drug screening and validation. In addition, we will further investigate the commercial feasibility of our product by conducting an elaborate market analysis and establishing a strong IP portfolio. The ultimate aim of MUSCLEGUY is to develop a business plan to convince the relevant stakeholders. Our novel 3D in vitro system for muscle disorder has the potential to meet the requirements for pharmaceutical drug discovery research (HTS format, reproducible and robust) and drastically reduce the associated costs and the number of animals used, in order to further increase the interest of the pharmaceutical industry for muscle disorders.

Keywords: 3d in vitro system,patient derived ipscs,muscle disorders,drug screening and drug validation
The role of macroPARAsite COinfection in Rodent-borne microparasite Transmission (PARACORT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-22
End date: 2016-08-21
Duration (months): 15.0
Total project cost (EUR): 112673.25
EU funding (EUR): 112673.25
Participants: 1
Project status: CLOSED

Rodent-borne microparasitic infectious diseases (e.g. LCMv), including those transmitted by the rodents’ ectoparasites (e.g. TBE), are of increasing concern for public health. Rodents themselves are also a threat to food security because they damage agricultural crops and food stores. Effective control of these emerging and re-emerging diseases (and the rodent hosts themselves) requires a full understanding of the parasite-host dynamic. This dynamic is likely to be altered where hosts are coinfected with prevalent endemic macroparasite species (e.g. helminths), which change host demography and may interact directly with microparasites via the host’s immune system. Using empirical data from a typical European temperate forest in the Autonomous Province of Trent (PAT), Northern Italy, this project will: i) first assesses which macro- and microparasites interactions exist among the common parasite community in this region (using advanced statistical methods), ii) develop a mathematical modelling framework to assess the long term dynamics of the rodent and parasite community and to simulate the outcome of a range of different parasite and host control strategies and iii) use this model to develop a co-ordinated ‘OneHealth’ plan for both rodent and parasite control in PAT .

Keywords: co infection,rodent borne disease,mathematical modelling,statistical modelling,pathogen control,disease transmission
CAPTURING THE PHYSICS OF LIFE ON 3D-TRAFFICKING SUBCELLULAR NANOSYSTEMS (CAPTUR3D)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Italy
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2021-03-01
End date: 2026-02-28
Duration (months): 60.0
Total project cost (EUR): 1985750.0
EU funding (EUR): 1860750.0
Participants: 2
Project status: SIGNED

Which physical principles govern life regulation at the level of subcellular, membrane-enclosed nanosystems, such as transport vesicles and organelles? How do they achieve controlled movements across the crowded intracellular world? Which is the structural and functional organization of their surface and their lumen? This is only a small subset of key open questions that the biophysical approach envisaged here will allow to answer directly within living matter, for the first time. Thus far, state-of-the-art optical microscopy tools for delivering quantitative information in living matter failed to subtract the natural 3D movement of subcellular nanosystems while preserving the spatial and temporal resolution required to probe their structure and function at the molecular level. CAPTUR3D will tackle this bottleneck. An excitation light-beam will be focused in a periodic orbit around the nanosystem of interest and used to localize its position with unprecedented spatial (~10 nm) and temporal (~1000 Hz frequency response) resolution. Such privileged observation point will push biophysical investigations to a new level. For the first time, state-of-the-art imaging technologies and analytical tools (e.g. fluorescence correlation spectroscopy), will be used to perform molecular investigations on a moving, nanoscopic reference system. The insulin secretory granule (ISG) is selected as a paradigmatic case study. Key open issues at the ISG level are selected, namely: (i) ISG-environment interactions and their role in directing ISG trafficking, (ii) ISG-membrane spatiotemporal organization, (iii) ISG-lumen structural and functional organization, (iv) ISG alterations in type-2 diabetes (T2D). These issues will be tackled directly within human-derived Langherans islets. CAPTUR3D is envisioned not only to foster our knowledge on T2D physiopathology but also to concomitantly drive an unprecedented revolution in the way we address living matter at the subcellular scale.
NESCIO: NEtherlands Science Conference on Inclusive Open science (Open Science)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Coordination and support actions
Countries involved: Netherlands
Call: Europe (H2020-Adhoc-2014-20, 2016)
Start date: 2016-04-01
End date: 2016-09-30
Duration (months): 6.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The Project is a two-day Open Science Presidency Conference, which is to be held on 4-5 April 2016 and organised in the Netherlands. Its core theme is ‘Open Science: from Vision to Action’. On day one, the focus will be on: 1. Creating Awareness for the need to make a transition towards an open science system. 2. Raising Political Support for Open Science, the Open Science Agenda and the start of the EC Open Science Policy Platform. On day two, the focus will be on: 3. Presenting a European Action Agenda on Open Science The key objective of this Conference is to bring together stakeholders (universities incl. libraries, researchers, funding organisations, publishers) and member states and EC to agree upon a joint perspective and view on realizing open access to scholarly publications by 2020 and to set up a platforms and infrastructure to make optimal (re-)use of research data possible. At the conference there will be the announcement of an Open Science Policy Platform (by EC) and an Action Agenda on Open Science (with focus on open access and open data) that addresses short/medium/long term goals for stakeholders, member states and European Commission. - Science is about curiosity, understanding, discoveries, new knowledge and maximum transfer of knowledge, not only within science but also to transfer knowledge to society and innovative businesses. - We should invest in science and increase its returns (which is more than going for maximum impact factor scores in a ‘publish or perish’ culture), because research is at the basis of innovation, growth and welfare. The results of the Conference will be used as input for the Council Conclusions of the Competitiveness Council in May 2016, and as input for the Open Science Policy Platform. These Conclusions will be the start of concerted action in Europe on Open Science, raising the impact of science on science itself, on economy and on society by defining concerted actions to change the science system in Eur

Keywords: open science,presidency conference,data management,open access,action agenda
Digitalization of outdoor advertising (WOW)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: SME instrument
Countries involved: Lithuania
Call: New business models for inclusive, innovative and reflective societies (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-02-01
End date: 2017-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

SMEs and non-profits are currently at a disadvantage due to high barriers to using outdoor advertising, which in principle could be one of the most effective advertising channel for small businesses: (1) running outdoor advertising campaigns currently requires significant investment (>€1000) and commitment and (2) outdoor advertising has limited targeting options and therefore low efficiency for local businesses having few physical locations and niche target groups. Intenova addresses this challenge in a scalable way and uses strategy which aims to maximise the impact on the competitiveness of SMEs and non-profits. Intenova develops an outdoor advertising platform based on digital displays attached to cars. The content of the display is changing in real-time based on targeting preferences (car's location, time, audience, and budget limits) set by the advertiser through a bidding platform. The platform creates flexibility and opportunities for business model innovation for SMEs and non-profits who are now able to (1) deliver messages to exactly those communities that are relevant for their business and (2) organize outdoor advertising campaigns even with very limited budgets thanks to more precise targeting and low setup costs. Field testing has shown that compared to other outdoor advertising channels, SMEs were able to increase the number of received quotes by up to 150% and sales by up to 50% for the same budget. Intenova has validated the business concept, run pilot projects using printed stickers, and is expecting revenues of €150 000 in 2016. The proprietary digital display technology was demonstrated in summer 2016 together with the first version of the software platform. For full-scale commercialization, Intenova needs to prepare for mass-production of the display, refine software modules and algorithms. Intenova’s ambition to become one of the leading providers of digital outdoor solutions has potential to generate in excess of €1 billion annually.

Keywords: business model innovation,outdoor advertising
EU Training Network for Resource Recovery through Enhanced Landfill Mining (NEW-MINE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Austria,Germany,Italy,Austria,Germany,Italy,Switzerland,Belgium,Belgium,Sweden,Sweden,Belgium,Sweden,Belgium,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2016, 2016)
Start date: 2016-09-01
End date: 2020-08-31
Duration (months): 48.0
Total project cost (EUR): 3836165.55
EU funding (EUR): 3836165.55
Participants: 17
Project status: CLOSED

Europe has somewhere between 150,000 and 500,000 landfill sites, with an estimated 90% of them being “non-sanitary” landfills, predating the EU Landfill Directive of 1999. These older landfills tend to be filled with municipal solid waste and often lack any environmental protection technology. In order to avoid future environmental and health problems, many of these landfills will soon require expensive remediation measures. This situation might appear bleak, but it does present us with an exciting opportunity for a combined resource-recovery and remediation strategy, which will drastically reduce future remediation costs, reclaim valuable land, while at the same time unlocking billions of tonnes of valuable resources contained within these landfills. However, the widespread adoption of Enhanced Landfill Mining (ELFM) in the EU, as envisaged by NEW-MINE, urgently requires skilled scientists, engineers, economists and policy makers who can develop cost-effective, environmentally friendly ELFM practices and regulatory frameworks. All this demands a European commitment to concerted, inter- and transdisciplinary research and innovation. The NEW-MINE project trains 15 early-stage researchers (ESRs) in all the aspects of landfill mining, in terms of both technological innovation and multi-criteria assessments for ELFM. The technological innovation follows a value-chain approach, from advanced landfill exploration, mechanical processing, plasma/solar/hybrid thermochemical conversion and upcycling, while the multi-criteria assessment methods allow the ESRs to compare combined resource-recovery/remediation ELFM methods with the “Do-Nothing”, “Classic remediation” and “Classic landfill mining with (co-)incineration” scenarios. By training the ESRs in scientific, technical and a range of soft skills, all based on a collaboration involving EU-leading institutes, they become highly sought-after scientists and engineers for the rapidly emerging ELFM and recycling industries.

Keywords: circular economy,recycling,raw materials,landfill mining,thermochemical conversion,low carbon building materials,syngas,multi criteria assessment,remediation,exploration
A novel shrouded vertical axis wind turbine for power generation in buildings (WindiBox)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Cyprus
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-06-01
End date: 2018-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The reasoning which emerges the need for creating WindiBox is to effectively tackle the existence of limited wind turbine applicability for wind energy generation in buildings on a global scale. There is an obvious technological gap in the market, covering the exploitation of low speed air flows, especially in urban environments and areas where the dynamics of air are low and do not allow the installation of common wind turbines. According to the requirements imposed by the Energy Performance of Buildings Directive all new buildings must be nearly zero-energy by the end of 2020. All new public buildings must be nearly zero-energy by 2018. The WindiBox device is comprised of a vertical axis wind turbine, enclosed inside a box-shaped, convergent-divergent casing (diffusers). This casing has been proven to augment the rotational speed of the wind turbine by a factor of at least 2.5, compared to a stand-alone turbine and additionally, enhancing its power output by at least 3 times. WindiBox size of 1m height – 2.5m width – 4m length offers power outputs ranging from 2700-3400kWh annually for wind speed 5m/s. The casing is also utilized to act as an environmental shield for minimal noise and vibration emissions since its extended surface area can be exploited for the addition of insulation. WindiBox overcomes the technological limitations of existing solutions in the market as well as the targeted milestones for CO2 emissions imposed by the European Union. What differentiates WindiBox from the competition is that it offers an unparalleled cost-effective solution of ROI less than 4.5 years for 5m/s with exceptional performance characteristics, disrupting the existing market of renewables. Our goal is to bring the WindiBox solution to market, after preparing an elaborate business plan. According to our initial plan, within 5 years from WindiBox commercialization, revenues will reach an annual total of approximately 19.2 million euros and net profits estimated at 30%.

Keywords: wind energy,renewable energy,smart city,building aesthetic,environment sustainability
Bacterial, cellular and epigenetic factors that control enteropathogenicity (BacCellEpi)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: France
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2015-10-01
End date: 2019-09-30
Duration (months): 48.0
Total project cost (EUR): 1147500.0
EU funding (EUR): 1147500.0
Participants: 1
Project status: CLOSED

Understanding the establishment and persistence of bacterial infections in the gut requires integrating an ensemble of factors including bacterial and host components and the presence of other microorganisms. We will capitalize on 25 years of studies on the bacterium Listeria monocytogenes used as a model, to focus on three objectives which will significantly increase our knowledge of the bacterium, of the cell biology of infection and of the epigenetic reprogramming upon infection. Our aims are: - at the bacterial level : to describe for the first time, the proteomic landscape of a bacterium during switch from saprophytism to virulence. We will use a proteogenomic approach together with ribosome profiling, to analyze the translation of the whole transcriptome after bacterial growth in several conditions, including in vivo, in order to barcode all the proteins which play a role in infection. This will open the way to assess the role of 1) small proteins; 2) internal translation initiation sites ; 3) the coupling of transcription and translation. - at the host cell level : To decipher the molecular mechanisms underlying the dynamics and role in infection of host intracellular organelles, starting with mitochondria. - At the host epigenetic level : To explore how the microbe reprograms host transcription and how tolerance to a commensal such as Akkermansia muciniphila differs from responsiveness to a pathogen insult, at the level of histones and mRNA modifications by studying 1) chromatin remodeling, in particular histones modifications during infection ; 2) modifications of the epitranscriptome during Listeria infection and colonization with Akkermansia ; 3) whether there is an epigenetic memory of infection and colonization. This ambitious multidisciplinary project will not only generate new concepts in infection biology but also will unravel fundamental mechanisms in microbiology, cell biology, and epigenetics opening new avenues for further research.

Keywords: epigenetics and infection
Expanding Agency: Women, Race and the Global Dissemination of Modern Architecture (Expanding Agency)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Ireland
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2022-01-01
End date: 2026-12-31
Duration (months): 60.0
Total project cost (EUR): 2082906.0
EU funding (EUR): 2082906.0
Participants: 1
Project status: SIGNED

Expanding Agency will explore the role that women and members of ethnic minorities, primarily African-Americans, played in transmitting modern architecture and design internationally, including within Europe, between 1920 and 1970. Strands devoted to patronage, journalism, entrepreneurship, and institution building will offer alternatives to accounts that focus primarily on architects. This will expand our understanding of who had agency in this important story and more generally in the shaping of the built environment. Taking a global approach that stresses comparisons across continents will also help build a more nuanced understanding of how architecture, landscape architecture, interior decoration, and the design of furnishing are transformed by new ideas that emanate from a multiplicity of sources. This in turn can help support a more diverse profession that, in the wake of #metoo and Black Lives Matter, is better prepared to engage with a broad public, including to address such social challenges as the integration of migrants and sustainability.

Keywords: history of architecture,design history,modernism,gender,race,african american,global histories,print culture