Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
SARIDAS: Saratoga Integrated Dental Simulation Platform (SARIDAS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Dental departments are losing clinical faculty to private practice as it is a more lucrative option. The effect of the loss of dental faculty requires dental institutes to find ways to meet the student needs during practicals. Saratoga S.p.A is a company that was established in 1973 that manufactures dental equipment, furniture as well as dental educational tools and systems. Saratoga has developed SARIDAS which is a computerised, dental artificial intelligence-based platform that responds to the challenges faced by dental students and clinical faculty. SARIDAS consists of four components. It contains a smart dental simulator that has a phantom head in which oral diseases are replicated for the student to practice treatment procedures. It also possesses an interactive tool that transmits images, videos and audio between workstations allowing for communication between a student and the instructor. The third component is an augmented reality unit which tracks the handpiece in the mannequin’s oral cavity and provides highly accurate assessment of student’s work. The last component is an artificial intelligence software ‘brain’ that interconnects the above 3 components and also contains a database in which clinical data about different oral conditions and the methods of treatment can be stored for use by the students. The smart brain component provides predictive technology and offers guidance to students on how to treat diseases that they have not yet encountered in the classroom. Our system provides unlimited practice from multiple pre-recorded dental exercises and the database provides students with access to international pathology data. SARIDAS offers instant feedback for correction where students would otherwise only be able to practice when the instructor is available. Our system allows for self-determined learning which is key for student success.

Keywords: smart dental simulator,artificial intelligence,multi sensorial learning,augmented reality component
Metabolic regulation of reciprocal signalling between skeletal muscle cell types (MUSIC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 184707.84
EU funding (EUR): 184707.84
Participants: 1
Project status: CLOSED

Maintenance of skeletal muscle quantity and quality is crucial for healthy aging, and is facilitated by a remarkable tissue plasticity. Muscle-resident stem cells (MuSC) provide an important contribution to this plasticity by differentiation and subsequent fusion with the myofiber – a process called myonuclear accretion. The progression of this process is characterised by distinct MuSC metabolic requirements, and seems to depend on the myofiber metabolic state. We therefore anticipate a role of metabolism – and specifically, the metabolic regulator AMPKalpha2 – in myofiber to the MuSC signalling, directing MuSC fate towards myonuclear accretion. We explore this in three aims, that constitute ‘proof of principle’, ‘target identification’, and ‘target validation’. To achieve these aims, we ensure a two-way transfer of knowledge by combining my Cre/LoxP-based cell system, with the host lab’s primary MuSC isolation. These combined technologies also provide a platform to study myonuclear accretion in the context of other molecular targets and diseases. Furthermore, we will initiate an interdisciplinary collaboration to perform integrative phosphoproteomics and metabolomics, and get a unique insight in the myofiber to MuSC signalling. This will provide AMPKalpha2-targets that will be validated using advanced mouse models established at the host lab, and provides leads for research after the fellowship. Results will be communicated to a scientific and non-scientific audience by publication in scientific journals, conference presentations, via Twitter, workshops and open days. Since the host lab is at the forefront of myogenesis research, it will provide me with an ideal environment to improve my scientific network, and receive the relevant technical and personal training. Together with the innovative nature and interdisciplinarity of the project, this will give me the unique opportunity to reach professional maturity both during and after the fellowship.

Keywords: skeletal muscle regeneration,plasticity,cellular cross talk,myogenesis,myonuclear accretion,satellite cells
Inkjet Printed Ultrafast Batteries and Large Integrated Capacitors (iPUBLIC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Sweden
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2014-12-01
End date: 2016-05-31
Duration (months): 18.0
Total project cost (EUR): 150721.25
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Energy storage has become a global concern in modern society. With his ERC Advanced grant, Prof. Östling, an expert in solid state electronics from the KTH Royal Institute of Technology in Sweden, is trying to develop emerging devices based on silicon technology but with other materials than silicon, such as graphene and its analogue MoS2. These unique materials offer opportunities to novel applications, especially those related to energy storage. Prof. Östling and his team have recently developed an efficient inkjet printing technique to reliably deposit these materials at high resolution. They have been able to directly print graphene-based supercapacitors with good performance. In the new PoC project, they will employ the inkjet printing techniques to demonstrate a novel type of energy storage devices which are expected to possess both high energy density and high power density, and establish initial commercialisation steps. Although the novel devices have complicated structure, the full-printing solution will not evidently increase the production cost. Considering the improved performance, the effective cost is actually reduced. Furthermore, the printing solution facilitates scaling up during commercialisation. These printed ultrafast batteries have great potential to meet the urgent and increasing demands from the rapid growth of portable electronic devices and electric vehicles.

Keywords: inkjet printing,graphene,supercapacitors,lithium ion batteries
Blended Learning Course for Police Students: Death Notification with Responsibility (DNR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-06-01
End date: 2018-11-30
Duration (months): 18.0
Total project cost (EUR): 147000.0
EU funding (EUR): 147000.0
Participants: 1
Project status: CLOSED

The aim of the proposed transfer project is to develop the blended learning course „Death Notification with Responsibility“ (DNR) for police officers. In situations of unnatural death (accidents, suicides, terror attacks or other forms of violence), police officers have to deliver a death notification to the family members of the deceased. Unnatural death is the worst possible message to be delivered. It will change the lives of those informed decisively and will remain in their memories forever. The core findings of the ERC project „Narratives of Terror and Disappearance“ (NoT-240984) established the devastating social effects of uncertainty caused by non-information and the material absence of bodies in confrontation with violent death. Police officers have a big impact on the way the bereaved can cope with this event. Psychological disorders like depressions are among the long-lasting effects on victims, if communication in this situation fails. At present, no sufficient training is offered at police academies that would ensure the systematic implementation of victims’ right to information as protected by EU Directive 2012/29. DNR will enable police officers to prepare for death notification delivery through a multi-layered approach, integrating classroom education and group-work as well as interactive e-learning components on a range of topics related to death and communication in highly sensitive situations. DNR will be produced with the IT department of Stuttgart police headquarters. Asides from the technological production the collaboration with police is crucial for developing the content of DNR modules. The prototype will be tested and evaluated in the police academy of Duisburg/Germany where it will be integrated into a semester-based course on ethics and social skills. In case of success, DNR markets will be expanded to other professional groups and prepared for use in other countries.

Keywords: victims protection,death notification,police professionalization,blended learning,unnatural death,mourning cultures,stress prevention,communication skills
Minirhizotron: Phenology And Root TraitS (Mr.PARTS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-06-01
End date: 2019-05-31
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

Mr.PARTS investigates plant belowground carbon investment and the timing of root development . Root turnover is an important part of global carbon (C) cycles and plants may alter investment into root systems due to nutrient imbalances or droughts as well as under anthropogenic global change. However, soils are difficult to study and root biomass is highly spatially and temporally variable, especially as seasonal timing (phenology) of aboveground plant events may affect resource investment and growth periods belowground. I focus on advancing specially designed camera systems for belowground observatories (minirhizotrons; MR) for non-destructive root/soil system observation and repeatable quantification of root biomass, life/death status and traits, using frequent automated data collection and automatic data processing. I will develop new MR instruments and deploy them first in a greenhouse-based mesocosm at the host institution in a controlled and well monitored setting, then a transfer to the field in a thoroughly instrumented (e.g. multiple height eddy covariance CO2, above-ground phenology cameras, soil lysimeters) study site as part of an ecosystem-scale experiment manipulating nutrient stoichiometry in a seasonally dry savanna in Spain. Data streams from the MR instruments will be processed by machine learning techniques and compared and calibrated against manual measurements of root biomass and root traits made via conventional destructive soil coring as well as whole system above-ground phenology, water and carbon budgets, to identify links between above- and belowground phenology as well as root control over ecosystem C fluxes. In addition, a paired 13C isotope labelling experiment will investigate C partitioning to non- root biomass building pools (e.g. root exudates, mycorrhizal fungi, maintenance respiration) to produce an integrated budget of plant belowground C investment and the controls on root production.

Keywords: minirhizotron,roots,carbon cycle,nitrogen cycle,phosphorus cycle,stoichometry,soil science,mediterranean tree grass ecosystem
A social based online survey platform (Charity 24-7)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: SME instrument
Countries involved: Denmark
Call: New business models for inclusive, innovative and reflective societies (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-12-01
End date: 2018-02-28
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The Danish SME CSR Research aims to pursue a major opportunity through the maturation of a social based online platform – CHARITY 24-7 – that promotes simultaneously the online consumers’ surveys and charity donations. CHARITY 24-7 approach is based on a shared value business model that joins (i) the need for consumer’s data by consumer goods retailers/manufacturers/service companies from different sectors, (ii) the engagement of surveys participants and (iii) the need for donations by NGOs and charity organisations. Our plan with the current Phase 1 project is to validate the segments and geographic areas that will bring more value to CHARITY 24-7 at this stage – i.e. the ones with larger potential to trigger a chain-reaction, leading us faster to the critical mass goal. Other objectives include the business model validation and establishment of pricing strategy. Moreover, the end-user’s requirements and preferences will be established and the platform extra features defined. The implementation of the innovation project will place CSR Research ApS in a strong position to exploit a market potential over five years exceeding €15M aggregated revenues. The total donations are expected to reach €4.7M and the tendency is to increase as CHARITY 24-7 is deployed.

Keywords: online surveys platform,consumers analysis,charity,collaborative and social economy
Archaeology on the Edge: Northern Europe and the Circumpolar World (ArchSci2020)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Joint Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Taiwan, Province of China,Sweden,Sweden,Latvia,France,Netherlands,Netherlands,United Kingdom,United Kingdom,Denmark,Japan,Greenland,Denmark
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) (H2020-MSCA-ITN-2015, 2015)
Start date: 2016-04-01
End date: 2021-03-31
Duration (months): 60.0
Total project cost (EUR): 4074239.16
EU funding (EUR): 4074239.16
Participants: 20
Project status: CLOSED

ArchSci2020 will provide structured state-of-the-art doctoral training to the next generation of archaeologists and biomolecular scientists forging a new generation of biomolecular archaeologists. Few other academic disciplines have been so transformed in the last decade as Archaeology. ArchSci2020 meet the need of a new generation of researchers. International, intersectoral and interdisciplinary training will equip its early-stage researchers (ESRs) with specific research-related and transferable skills, in order to provide enhanced career prospects across academia, industry and the third sector. The proposed ArchSci2020 network will bring together four leading research clusters each with complementary expertise to deliver an integrated, flexible training package that will provide a sound basis for academic independence and preparation for vocations in the archaeology, heritage and beyond. ArchSci2020 will combine (i) a common purpose, (ii) an unconditional commitment to the student experience, (iii) a pro-active stance towards international, inter-institutional research support and interdisciplinary study, (iv) a simple but effective management structure provided by a Management Team, Supervisory Committee and the Work Package leaders, (v) and an established academic infrastructure and reputation. Key features of ArchSci2020: 1. ArchSci2020 will create a multidisciplinary training environment that brings together archaeologists, biologists, mathematicians, analytical chemists, and policy experts around an archaeological hub. 2. ArchSci2020 priorities and cross-cutting training themes align closely with ‘Grand Challenges’ across its themes of Health, Diet, and Environment and incorporates the important current skills and future training needs in archaeological science. 3. Each participating institution will make a unique and distinct contribution to the experience of Early Stage Researchers (ESRs) in a partnership formed from existing strong environments.

Keywords: biomolecular archaeology,palaeodiet,ancient health,technology,innovation,dispersal,human environment interaction
Deciphering the Metabolism of Haematological Cancers (HaemMetabolome)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Joint Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Spain,Germany,Netherlands,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-EJD) (H2020-MSCA-ITN-2015, 2015)
Start date: 2015-10-01
End date: 2019-09-30
Duration (months): 48.0
Total project cost (EUR): 2572664.04
EU funding (EUR): 2572664.04
Participants: 7
Project status: CLOSED

It has long been realised that metabolism is central to cellular development, proliferation and homeostasis. Collectively, aberrations in metabolism are now recognised as a major hallmark of cancer, opening new avenues for personalised medicine. As haematological malignancies are multi-factorial diseases, our main emphasis will be on the integration of biomedical multi-omics data and computational systems modelling with the ultimate aim to understand metabolic regulation in haematological cancers. HaemMetabolism is design to unravel the regulatory mechanisms that link cell cycle control and metabolism. For this we will screen a panel of haematological cancer cell lines for the metabolic phenotypes and against a library of inhibitors. Gene-function analyses will be performed using shRNA libraries directed against key metabolome regulators. Validation will occur in primary patient samples in vitro and in vivo in preclinical humanized niche xenograft mouse models. A systems biomedicine approach will be integrated build genome-scale transcriptional models that explain deregulated metabolic pathways relevant for the development of haematological malignancies. This work will not only open new avenues for drug discovery but will also provide a multi-disciplinary framework for student training in biomedical technologies.

Keywords: metabolism of haematological cancers
Grounding RRI practices in research performing organisations (GRRIP)

Framework: Horizon 2020 — Science with and for Society
Programme: Develop the governance for the advancement of responsible research and innovation by all stakeholders, which is sensitive to society needs and demands and promote an ethics framework for research and innovation
Action type: Coordination and support actions
Countries involved: Ireland,Germany,Ireland,Italy,Spain,France,France,Netherlands,United Kingdom,United Kingdom,Portugal
Call: Grounding RRI practices in research and innovation funding and performing organisations (H2020-SwafS-2018-1, 2018)
Start date: 2019-01-01
End date: 2022-12-31
Duration (months): 48.0
Total project cost (EUR): 1527718.75
EU funding (EUR): 1496468.75
Participants: 13
Project status: CLOSED

GRRIP will embed sustainable RRI practices in 4 research performing organisations (RPO) and 1 dual function RPO and research funding organisation (RPO/RFO) (total 5 RPO&RFO) in the Marine and Maritime (M&M) sectors through Action Plans (AP) for institutional and cultural change. This will be accompanied by establishing a platform for engagement with the Quadruple Helix (QH) for each RPO&RFO, and a platform for mutual learning between the 5 RPO&RFOs and QHs. M&M is a high priority for the EU. However, the M&M is seriously exposed to the non RRI alignment between Research and Innovation (R&I), societal actors and the environment, affecting its performance and competitiveness. Objective 1: Co-develop, implement and evaluate self-tailored RRI APs to enable sustainable institutional and cultural change for the 5 M&M RPO&RFOs to embed RRI in their governance frameworks, structures and cultures. The APs will be based on a detailed audit of the RPO&RFO current RRI maturity level and the barriers identified. RRI dimensions will be incorporated into R&I. Objective 2: Establish structures to facilitate, promote and maximise real sustainable engagement with, and input from, the QH (industry, societal actors, policy and other RPO&RFOs). Objective 3: Establish indicators and methodology for impartial Monitoring, Reflection and Evaluation cycles, to ensure provision of evidence of societal, democratic, economic and scientific impacts of institutional changes. Objective 4: Develop a sustainable Mutual Learning process across the M&M RPO&RFOs both during the institutional and cultural change project and thereafter. Objective 5: Legacy: To enable more M&M RPO&RFOs to ground RRI practices through institutional and cultural changes by a) creating a practical user-friendly RRI AP framework template & guidelines, and b) launching a M&M RRI community. Objective 6: Examine how an RFO can positively influence and encourage an RPO towards RRI via its funding policy and interaction.

Keywords: citizens,stem,gender equality,ethics,integrity,open access,institutional changes,interventions,marine and maritime,quadruple helix,industry,government,mutual learning,evaluation,morri