Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Art and Ethics: Restarting and Advancing a Stalled Debate (Art and Ethics)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

This project is a work of philosophy that investigates how intrinsic ethical properties are realized in artworks and other aesthetic and creative objects and practices, and in what respects their aesthetic values are determined by these properties. The project innovates in three principal ways. First, it identifies and articulates novel ways by which artworks and similar objects and practices come to exhibit ethical properties, where the existing literature in this area relies exclusively on just one way this can occur. Second, it diagnoses why the literature on the question of ethico-aesthetic value interaction has stagnated for almost a decade, by revealing the vague and inconsistent conceptual tools on which its theorists have relied until now, and which have inhibited its progress. Finally, it uses the preceding two innovations to articulate a new and satisfactory theory about how ethical properties determine aesthetic values. The project promises to radically transform a live, if currently inert, philosophical literature while offering a comprehensive strategy to share its interdisciplinary and public interest benefits with stakeholders beyond philosophy and indeed the academy.

Keywords: ethics,aesthetics,normativity,moralism,immoralism,metaphysics,oppression,gender,race
Smart and reliable solid biofuel quality control solution (OPTIFUEL)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain,Finland
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-10-01
End date: 2018-12-31
Duration (months): 27.0
Total project cost (EUR): 1699055.0
EU funding (EUR): 1189338.5
Participants: 2
Project status: CLOSED

The goal is to realize the global market opportunity related to a disruptive real-time solid biofuels quality control and optimization solution created, tested and proven by INRAY Ltd in cooperation with industrial anchor customers since 2009. The innovation enables biomass power plants to replace the current manual sampling method by real-time assessment and optimization of fuel handling and combustion, producing concrete value and savings both to a vast body of industrial customers and the society at large. For the entire EU’s bioenergy production, the OPTIFUEL solution could produce 1.5 Billion Euros in annual savings and decrease greenhouse gas emissions by 0,5-3,0 Million tons. OPTIFUEL also enables more effective use of local low quality biofuels, which would increase EU’s self-sufficiency in biofuels. For a mid-size biomass power plant, OPTIFUEL produces up-to 1 Million Euros in annual savings.

Keywords: solid biofuels,bioenergy production,process optimization,fuel quality control
Women’s Plague Writing in Early Modern England (Womenswriting)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom,Canada
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-01
End date: 2022-09-14
Duration (months): 36.0
Total project cost (EUR): 255349.8
EU funding (EUR): 255349.8
Participants: 2
Project status: CLOSED

In a time when high-profile outbreaks such as zika and ebola frequently make news headlines, the proposed research project, ‘Women’s Plague Writing in Early Modern England’, provides an opportunity to interrogate how we interpret medical writing, who talks about medical problems and how gender becomes entangled in outbreaks by looking to the past. ‘Women’s Plague Writing in Early Modern England’ will undertake a survey and analysis of women’s plague writing in England from 1550 to 1700. A three-year Global Fellowship project with a two-year outgoing phase at the University of Toronto (UofT) and incoming phase at Queen’s University Belfast (QUB), the research action takes an interdisciplinary approach to women’s plague writing across the early modern period in England. The research programme explores the medical humanities through the lens of literature in its historical context. This project will change the canon of plague writing, which has hitherto focused on male-authored texts. Moving from the single outbreak focus seen in my first monograph, The Literary Culture of Plague in Early Modern England (forthcoming with Palgrave Macmillan), the outcome of the project makes the significant leap to studying a period of plague writing, a bigger-scale picture, with a broad chronology that captures major plague outbreaks in 1592, 1603, 1625, 1630, 1636 and 1665. The project encapsulates a full-period picture of women’s interactions with plague and medicine and the corresponding gendering of plague writing. It will examine how women discuss the disease and how this differs from male-authored texts. It will ask how the medium chosen for publishing a text, print or manuscript, impacted how women discussed the disease. It will investigate how women’s understanding of plague was gendered and, more broadly, how the textual construction of pestilence was gendered in early modern England.

Keywords: early modern literature,women s writing,cultural history,medical humanities,medical history,plague writing,life writing,history of science,religious writing,recipe books,manuscript and print
The Swift GRB Host Galaxy Legacy Survey: Understanding the Link between GRBs and Star Formation from the Nearby to the Early Universe (SHOALS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-15
End date: 2017-05-14
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

I propose to carry out the Swift Gamma-Ray Burst Host Galaxy Legacy Survey (SHOALS), a multi-national, multi-facility, multi-wavelength eﬀort to characterize the gamma-ray burst host galaxy population and how it connects to other star-forming galaxy populations at high redshift. Gamma-ray bursts represent invaluable tracers of the conditions in distant galaxies and provide a unique means of measuring the contribution of the faintest and highest-redshift galaxies to stellar mass assembly, yet we still do not understand what their progenitor system is or what environmental inﬂuences cause GRBs to explode more frequently in certain types of galaxies than others. By intensively charactering a large population of uniformly-selected GRB hosts across cosmic history, I will disentangle the various factors that may inﬂuence GRB production (chemical composition, starburst intensity, population age) and apply these results to better understanding how these violent explosions are produced and how we can use them to better understand the earliest phases of galaxy evolution.

Keywords: star formation,gamma ray bursts,galaxies,early universe
Mechanisms of Regeneration Initiation (IniReg)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cellular, Developmental and Regenerative Biology
Panel description: Structure and function of the cell, cell-cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Germany,Netherlands
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-04-01
End date: 2022-03-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1307544.21
Participants: 2
Project status: CLOSED

Injury poses a key threat to all multicellular organisms. However, while some animals can fully restore lost body parts, others can only prevent further damage by mere wound healing. Which molecular mechanisms determine whether regeneration is induced or not is an unsettled fundamental question. I will use whole body regeneration, one of the most fascinating biological processes, as an experimental paradigm to identify the mechanisms of regeneration initiation. As a model organism I will employ planarians, flatworms with extraordinary plasticity that regenerate every piece of their body within a few days. I will mechanistically dissect how these animals rapidly induce an efficient regeneration program in response to tissue loss and define the key switches that determine whether a wound regenerates. Combining the astonishing regenerative abilities of planarians with new technologies I will first comprehensively describe the molecular changes occurring during the amputation response. Second, with a powerful novel assay developed in my lab - dormant fragments - that allows for the first time the separation of wounding from tissue loss in a single planarian, I will analyze the dynamics of the earliest regenerative events. Third, I will functionally characterize the regeneration-initiating signals and their target pathways combining in vivo RNAi and phenotypic assays. Fourth, with a regeneration-deficient planarian species, I will test whether the identified key regulators act as network nodes that can be utilized to rescue regeneration. Importantly, using vertebrate paradigms, such as the regenerating zebrafish fin, I will investigate conserved roles of these network nodes and validate general principles of regeneration initiation. This project will not only uncover conserved mechanisms of regeneration initiation but will also identify the switches that must be levered to induce regeneration in non-regenerating animals.

Keywords: tissue regeneration,animal models
Why does Clostridium botulinum kill? – In search for botulinum neurotoxin regulators (whyBOTher)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Finland
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2017-01-01
End date: 2023-12-31
Duration (months): 84.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Bacterial toxins cause devastating diseases in humans and animals, ranging from necrotic enteritis to gas gangrene and tetraplegia. While toxin synthesis probably endows these bacteria with a selective advantage in their natural habitats, toxigenesis is likely to represent a fitness cost. It is thus plausible that mild environments encourage bacteria to give up toxin production, or reduce the number of toxigenic cells in populations. The cellular strategies bacteria use to silence toxin production and to establish stably non-toxigenic subpopulations represent targets for innovative antitoxin and vaccine strategies that can be utilized by the food, feed, medical, and agricultural sectors. I have found the first repressor that blocks the production of the most poisonous substance known to mankind, botulinum neurotoxin (BOT). This toxin, also known as “botox”, kills in nanogram quantities and is produced by the notorious food pathogen, Clostridium botulinum. In whyBOTher, I will extend the knowledge from this single regulator to comprehensive understanding of how C. botulinum cultures coordinate BOT production between single cells and cell subpopulations in response to their physical and social environment, and which genetic and plastic cellular strategies the cells take to attenuate BOT production in short and long term. I will experimentally force evolution of BOT-producing and non-producing cell lines, and explore the genetic, epigenetic, and cellular factors that explain the emergence of the two cell lines. To achieve this goal, I will extend the research on C. botulinum biology in two dimensions: from population level to fluorescent single-cell biology, and from genomic information to functional analysis of regulatory and metabolic networks controlling BOT production. whyBOTher represents an unprecedented research effort into regulation of bacterial toxins, and introduces a shift in paradigm from population-level observations to the life of single bacterial cells.

Keywords: food safety,food poisoning,clostridium botulinum,clostridium,botulinum neurotoxin,clostridial toxin
digital iNtegrAteD system for the socIal support of migraNts and refugEes (NADINE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Innovation actions
Countries involved: Spain,Italy,Greece,Greece,Belgium,France,Luxembourg,United Kingdom
Call: Addressing the challenge of migrant integration through ICT-enabled solutions (H2020-SC6-MIGRATION-2018, 2018)
Start date: 2018-11-01
End date: 2021-10-31
Duration (months): 36.0
Total project cost (EUR): 4953131.25
EU funding (EUR): 3970576.5
Participants: 13
Project status: CLOSED

NADINE project aim is to develop a novel way of integrating migrants and refugees through ICT-enabled solutions that will automatically adapt to the specificities of each person. The consortium agrees that one of the main enablers of migrants/refugees inclusion, in the host societies, is their ability to work. Hence NADINE's motto is "Give migrants and refugees their dignity back by giving them a decent job with a decent salary". Taking into account this important factor, NADINE will create an adaptable platform able to: 1) Provide functionalities for skill assessment, 2) dynamically create tailored suited training programs to adapt existing skills into host societies needed skills, 3) provide a digital companion that will suggest and assist the end-users through administrative tasks and 4) create a data lake available to public administration bodies for better organisation of migration flows. NADINE will innovate in several directions from novel training tools, adaptable to different learning setups, to novel ways of information flow handling for public administrations to work efficiently in both business as usual contexts and migration bursts ones. NADINE platform will create potential new markets in different market areas and also will provide novel open tools that will foster new innovation capacity to the EU area.
Lossy Preprocessing (LOPRE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Norway
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-05-01
End date: 2025-04-30
Duration (months): 72.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

A critical component of computational processing of data sets is the `preprocessing' or `compression' step which is the computation of a \emph{succinct, sufficiently accurate} representation of the given data. Preprocessing is ubiquitous and a rigorous mathematical understanding of preprocessing algorithms is crucial in order to reason about and understand the limits of preprocessing. Unfortunately, there is no mathematical framework to analyze and objectively compare two preprocessing routines while simultaneously taking into account `all three dimensions' -- -- the efficiency of computing the succinct representation, -- the space required to store this representation, and -- the accuracy with which the original data is captured in the succinct representation. ``The overarching goal of this proposal is the development of a mathematical framework for the rigorous analysis of preprocessing algorithms. '' We will achieve the goal by designing new algorithmic techniques for preprocessing, developing a framework of analysis to make qualitative comparisons between various preprocessing routines based on the criteria above and by developing lower bound tools required to understand the limitations of preprocessing for concrete problems. This project will lift our understanding of algorithmic preprocessing to new heights and lead to a groundbreaking shift in the set of basic research questions attached to the study of preprocessing for specific problems. It will significantly advance the analysis of preprocessing and yield substantial technology transfer between adjacent subfields of computer science such as dynamic algorithms, streaming algorithms, property testing and graph theory.

Keywords: kernelization,parameterized complexity,approximate kernelization
Smart Online Searching To Increase Patient Safety (SOS TIPS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-08-01
End date: 2024-07-31
Duration (months): 36.0
Total project cost (EUR): 253052.16
EU funding (EUR): 253052.16
Participants: 2
Project status: SIGNED

The spread of misinformation has been attributed to an increasingly digitalized and fractionalized information landscape. In such a milieu, relevance-based online environments can create “alternative epistemologies”, spawning distinct ways of consuming information that can be shared by millions in so-called “epistemic communities”. Information consumption and digital health literacy (ability to seek, understand, and appraise online health information) have a prominent effect on health outcomes and doctor-patient communication. Our initiative aims to increase digital health literacy via the development of guidelines for “Smart Searching”: how to conduct well-rounded searches, judge the reliability of online content, warning signs of questionable trustworthiness, and practical techniques aiding informed decision-making. These guidelines, primarily implemented in a browser extension scaffolding critical thinking, will be based on an empirical study examining how particular epistemic communities (anti-vax; users of alternative medicine) interact with online content and determine trustworthiness. The study will be conducted with a methodological innovation that enables the integration of eye-movement, human-computer interaction, and qualitative data in order to triangulate data types and thus better understand cognitive processes in online behavior. Our open source tool will comprise part of a larger kit: a unified qualitative-quantitative framework for integrating all three data types, a standard with which the tool can be implemented, and an open data depositing system. The initiative’s pivotal objective is to increase digital health literacy among the general public and to create a reproducible and sustainable system for future research aimed at understanding online information-seeking behavior. Gaining a deeper insight into information consumption within epistemic communities is essential in ensuring health equity and patient safety in a digitalized world.

Keywords: health and illness behavior,information seeking,decision making,epistemology,misinformation,vaccine hesitancy,patient safety,digital health literacy,software development,open science
Energy Smart Livestock Farming towards Zero Fossil Fuel Consumption (RES4LIVE)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Innovation actions
Countries involved: Italy,Italy,Germany,Germany,Italy,Cyprus,Belgium,Belgium,Greece,Belgium,Greece,Greece,Sweden,Greece,France,Denmark
Call: Defossilising agriculture – solutions and pathways for fossil-energy-free farming (H2020-FNR-2020-1, 2020)
Start date: 2020-10-01
End date: 2024-09-30
Duration (months): 48.0
Total project cost (EUR): 5815206.88
EU funding (EUR): 4998554.95
Participants: 17
Project status: SIGNED

The adaptation of RES technologies and machinery and their demonstration at a large-scale on farm level, require supporting measures with respect to spatial planning, infrastructure, different business models and market organisation, trends that are not all under control from a farmers’ perspective. RES4LIVE project will fill these gaps ensuring a wider adoption of RES and energy efficiency technologies, machinery and techniques in livestock farms towards a zero-fossil fuel consumption. A great part of RES4LIVE technical work deals with the adaptation of specific technologies for both renewable energy and biofuels so that to perfectly fit livestock farming and becoming attractive in terms of cost effectiveness, operational flexibility and with low maintenance. The key technologies include PVT systems, modular heat pumps, biogas upgrading to biomethane, and tractors retrofitting to be fuelled by biomethane. Except these technologies, standard RES and other solutions are included in the integrated energy system, such as the use of PV panels, geothermal energy, and electrification of on-farm machinery. The RES4LIVE project emphasises on the demonstration of the selected technologies in 4 pilot farms in Belgium, Italy, Germany and Greece, for a duration of at least 12 months, to serve as the means of de-fossilising evidence and impact generation. The aim is to totally replace the fossil fuel consumption of certain needs in the pilot farms, proving that fossil-free-energy farming is possible to be achieved with a sustainable way. At the same time, the replicability potential is another key activity so that to prepare the commercialization process of the solutions. The overall objective is to provide advanced and cost-effective technologies to the livestock sector that ensure the sustainability of the farms’ operation, and the superior thermal comfort of the animals for increased productivity with minimum climate change impact.

Keywords: heat pump,biomethane,biogas upgrading,smart control,energy management,pvt system,biomethane fuelled tractor,pilot testing,livestock thermal comfort,energy efficiency,geothermal energy