Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Decorative Applications for Self-Organized Molecular Electrochromic Systems (DecoChrom)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Innovation actions
Countries involved: Austria,Germany,Germany,Spain,Italy,Poland,Finland,Sweden,Finland,France,France,Czechia,Denmark,United Kingdom,Portugal,Portugal,Portugal,Portugal
Call: Advanced materials and innovative design for improved functionality and aesthetics in high added value consumer goods (H2020-NMBP-2017-two-stage, 2017)
Start date: 2018-01-01
End date: 2022-06-30
Duration (months): 54.0
Total project cost (EUR): 7333457.96
EU funding (EUR): 6640599.13
Participants: 18
Project status: CLOSED

The DecoChrom project elevates printed graphics products to the age of interactivity, and empowers the creative industries with the tools and innovative advanced material sets to design and build aesthetically pleasing practical human interfaces to smart consumer goods and environments. The DecoChrom consortium develops printed electrochromics (EC) as the mass producible, print industry compatible, ultra low-power interactive graphics solution for ambient intelligence. DecoChrom will scale-up the production of advanced composite materials into 3 innovative ink EC colours, manufacturing process on different materials (plastic foil, paper, high-pressure laminates and 3D durable plastic parts), wide dissemination and creation of EC toolkits to introduce electrochromics to designers, makers and the printing industry, and finally the co-creation of more than 20 creative industry lead end-user prototypes and pilots for architecture, interior design, lifestyle and sports. The project brings together a strong interdisciplinary consortium of 15 partners, industry and research balanced, with state-of-the-art backgrounds in design, chemistry, printing, coatings and laminates, electronics system integration, and complete electrochromics solutions. This is complemented with the commitment of a multidisciplinary Industrial Advisory Board with representation of key industry end-users such as Ikea (furniture), Lego (toys), BMW (automotive), Fiskars (domestic tools), Hoffmann + Krippner (printed electronics, industrial printing) and GSB Wahl (ink production).

Keywords: creative industries,electrochromic materials,printed electronics,interactive surfaces,high pressure laminates,industrial printing
Cost-efficient, 35 seconds, comprehensive mastitis management system for dairy farmers and veterinarians (MastCloud)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: Bulgaria
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-1-2015, 2015)
Start date: 2016-03-01
End date: 2016-06-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

On dairy farms, mastitis or udder inflammation often is the most common disease and the major reason for antibiotics use. Annual losses in the milk supply chain due to mastitis are estimated to be over 1 billion euro in Europe, with similar figures in other parts of the world. In order to reduce these losses, we propose an innovative Cloud-connected mastitis management system composed of an instrument and a modular software suite. Our solution will significantly improve resource efficiency and energy efficiency in the milk production industry. For the instrument, we use a widely accepted mastitis indicator: somatic cell count. We digitize and automate a famous test method: CMT (California Mastitis Test). The average measurement duration of the system will be 35 seconds for typical farm mastitis incidence rates and the operating cost will be less than 0.02 euro per test. The instrument comes with guaranteed high correlation with official lab results. We adopt recent evolutions in mobile devices and IT technologies in order to enable affordable smart farming and tele-vet services through automated analysis, dashboards and remote diagnosis modules. Through our embedded algorithms, we are putting into practice research from universities in Belgium and other countries around milk quality and animal health. Our solution will respond to the current tendency with less frequent official milk quality recordings by dairy herd improvement (DHI) associations, while instead enabling efficient on-farm measurements. The existing on-farm mastitis management systems on the market suffer from high operating costs, are too complex or unreliable hence are no solution for the majority of the 1.5 million dairy farms and their veterinarians in Europe. During Phase 1, we want to perform a feasibility study, to refine our cost and profit estimations with detailed figures and perform a design study. Finally we will create a detailed business plan.

Keywords: dairy supply chain,sustainable farming,antibiotics use,milk quality,animal health,tele vet services,remote diagnosis,mastitis,subclinical mastitis,udder infection,somatic cell count
Inaudible SMART CROWDS SECURITY through existing loudspeakers” (Zoovel-UC)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Spain
Call: Engaging SMEs in security research and development (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-10-01
End date: 2017-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Zoovel Ultrasound Connectivity (Zoovel-UC) project is a D2D connectivity to raise the safety and security in crowded areas such as sports stadiums, concert halls, open space events, subway, etc. providing real-time crowd management. Zoovel-UC technology performs direct and selective communication to the spectators and utilizes geospatial intelligence to shift the flow of fans and minimize crowds in real-time, improving the efficiency of current security protocols. Since the attack on the Twin Towers in 2001, terrorism has been on our collective unconscious as the main threat to security. The recently attacks happened in Paris and Brussels again reminded the vulnerability of the international security system and the difficulty to deal effectively with this type of unconventional threat. Crowd events provide a potential target for terrorist activity, besides they are susceptible to other various threats, such as natural disasters, crowding and fan violence. With the uncertainty of terrorist actions and fan behaviour, it is impossible to ensure a risk-free environment at crowd venues. It is therefore a matter of how event organizers prepare, respond, and recover to mitigate the consequences of emergencies. Good countermeasures and contingency planning can protect crowd areas from disruption and ultimately enhance spectator confidence.

Keywords: security,communication,telecommunications,smart stadium,ultrasound,data over audio,crowd magnament,inaudible z tones
Estimating the Prevalence of AntiMicrobial Resistance (EstAMR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-04-01
End date: 2022-07-31
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: CLOSED

Antimicrobial resistance (AMR) is the ability of an infection to stop antimicrobials, such as antibiotics, antivirals and antimalarials, from working against it. In the EU, every year AMR is responsible for thousands of deaths and costs millions of euros. Yet forecasting the prevalence of AMR remains an open challenge. This project meets this challenge by developing cutting-edge Hierarchical Bayesian models (HBMs). As a case study, the models will focus on the malaria parasite Plasmodium falciparum that has developed resistance to sulfadoxine/pyrimethamine between 1994 and 2016. This ensures that the goals are realistic, with immediate insight and impact, whilst also remaining methodologically relevant for all AMR. Within the field of ecology, regression models are being replaced so as to incorporate more complex non-linear relationships between abundance and the environment. Unlike traditional methods, HBMs are spatiotemporal models that (i) account for varying geography (ii) separate underlying processes and (iii) include uncertainty in the data and model parameters. This thorough package has proven to yield more insight and accuracy. By using partial differential equations, HBMs separate occurrence due to spread and occurrence due to emergence. Despite its relevance, differentiating between these two process is currently unexplored in epidemiology. Furthermore, when modelling AMR, infections competing for hosts is a process which is currently unexplored in HBMs. Thus, the two long term contributions of this project are: Bringing HBMs to epidemiology to gain a better understanding of underlying processes, and advancing the field of HBMs to include more complex dynamics. And more immediately, the two key contributions are: Quantifying the dynamics and influencers of the spread of drug resistant malaria, and forecasting the frequency of partially drug resistant malaria, and fully drug resistant malaria, at different locations and at different times.

Keywords: mathematical model,malaria,resistance,hierarchical bayesian model,spatiotemporal
Modified Vacuum Rankine Cycle (MOVARC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-06-01
End date: 2018-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

MOVARC is a new thermodynamic cycle (inspired in both Rankine and Stirling cycles) coupled to an innovative transmission design working to generate energy from industrial waste-heat and other mid-level renewable eat sources such as biogas. The new thermodynamic cycle is patent protected and its innovation lies in the use of a closed-system vacuum chamber that increases the overall efficiency of the system. MOVARC does not require a turbine for energy generation, instead it relies on a transmission system and lineal work outputs. Mathematical models and experimental tests on the TRL6 prototype indicate an increase of efficiency of η=8-9% over competing solutions. In other words, MOVARC cycles transform mid & low-heat resources (industrial waste-heat or biogas) into energy at higher efficiency than current technologies including organic Rankine cycles, Kalina cycles, and Supercritical CO2 cycles. The lineal work generated by MOVARC is translated into rotational energy (via the patented transmission gear) and captured by a commercial electromagnetic generator to produce electricity. The transmission system that delivers the required linear-to-rotational exchange is also patented and was engineered for-purpose. The mechanical losses in the transmission are controlled using a novel bevel gear design with proven efficiencies in industry settings of η=98-99% for low RPM and near constant speed; both characteristics of MOVARC. We estimated that turnover related to MOVARC will reach €7.00 million by 2024, generating profits of €1.75M cumulatively. It is equally foreseen that the consortium we will grow in employees (9 new hires planned), specifically, in the manufacturing and business development and the research team at Cobertrans. Improved efficiencies (up to 9%) and lower €/KWh generation allows MOVARC to have a remarkedly inelastic pricing.

Keywords: thermodynamics,waste heat to power,biogas,landfill,waste,incineration,anaerobic digestion,rankine,kalina,supercritical co2,industrial and domestic waste,repurposing of waste
Multi-functional DUAL PHOSphorus-based organoCATalysts for stereoselective ring-opening polymerisation (DUAL-PHOSCAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-08-01
End date: 2019-07-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 2
Project status: CLOSED

The stereocontrolled ring-opening polymerisation (ROP) of chiral cyclic esters for the preparation of biodegradable polymers with precise and finely-tuned properties remains a research challenge. Only Few catalysts/initiators have been reported to produce stereoregular high molecular weight polymers; most of them being highly sensitive and/or toxic organometallic species. Organocatalysed ROP produces polymers that are free of residual metal contaminates but to date, does not allow high productivities with high levels of stereocontrol. In this context, the multi-disciplinary proposal DUAL-PHOSCAT proposes to develop chiral tunable dual phosphorus-based organocatalysts to overcome these challenges. For this, a stepwise-synthesis strategy to tailor the organocatalyst architectures and an inventive combinatorial approach using self-assembled oganocatalysts will be investigated. The stepwise synthesis will bind together using chiral linkers, chiral phosphorus-based molecules and chiral thioureas molecules.The self-assembled dual organocatalysts will be obtained combining chiral amine-thioureas and chiral phosphoric acids. These systems will be investigated for the ROP of rac-lactide and rac-beta-butyrolactone. The proposed catalysts enable great advances in the preparation of isotactic polylactide (PLA) stereocomplex and highly tactic poly-3-hydroxybutyrate (PHB) in terms of catalyst stability, productivity, activity and stereoselectivity, in turn making these catalysts efficient green alternative to sensitive and /or toxic organometallic initiators for the synthesis of metal-free highly stereoregular polyesters under industrially-relevant conditions. The PLA and PHB obtained will find potential applications in packaging and fibers (as green alternative to petroleum-based plastics) or as biomedical devices that is in line with the H2020 programme (e.g. Climate action, environment, resource efficiency and raw materials and Health, Demographic and well-being).

Keywords: ring opening polymerisation,organocatalysis,biodegradable polymers,asymmetric catalysis,self assembled catalysts
SMART BONE REGENERATION (SBR)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Germany,Switzerland,Switzerland,Greece,France,France,United Kingdom
Call: Regenerative medicine: from new insights to new applications (H2020-SC1-2019-Single-Stage-RTD, 2019)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 6379337.5
EU funding (EUR): 6379337.5
Participants: 11
Project status: SIGNED

The management and reconstruction of bone defects is a significant global healthcare challenge. While autografts offer ideal compatibility, they are often not suitable for large bone defects, and allografts suffer from potential immunorejection.The limited efficacy of conventional treatment strategies for large bone defects and the increasing aged population, has inspired the consortium to propose a SMART RESORBABLE BONE (SRB) IMPLANT embedding stem cells and bioactive agents with the aim of a controllable and fast restoration. The proposed solution includes 3D printed medical grade polymers enriched with electrospun fibers (for increased mechanical properties) that can be customized for patient physiology, pathology, and gender. The scaffold design will ensure easy and minimal Injury placement, and will embed different sensors for monitoring e.g. pressure, pH value and temperature based on biocompatible conductive inks. The smart implant will thus be able to provide vital information of implant performance in terms of bone growth and infection/inflammation. The proposed method is unique because it includes a customized smart implant (3D printed parts with adjustable sensors and communication electronic system), together with tissue engineering methods i.e. in-vitro programming of stem cells for embedding into the smart implant. The proposed solution introduces an innovative regenerative chain, from early testing and characterization (identification/adjustement of the proper specifications) and embedding regenerative stem cells and particulate bioactive agents into the smart implant in preclinical research (in-vitro). The in vivo proof of concept of SBR solution will be tested in (large animal model) preclinical studies within the scope of the project. Finally the regulatory and commercialization strategy on how to further explore the proposed concept and deliver it for clinical testing will be elaborated.

Keywords: bone defect,implant,fracture,regeneration,stem cells,3d printing,sensors,wireless,biocompatible conductive inks,bioactive agents,in vitro testing,in vivo testing
Re-engineering of fungal sulphur metabolism to limit mould viability and virulence. (Sulphirulence)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-02-01
End date: 2018-01-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Aspergillus fumigatus, the major mould pathogen of human lungs, is responsible for > 2 million illnesses per annum in Europe . I have discovered that sulphur is an essential host-derived element during A. fumigatus infection . This finding is novel, and highly exploitable as a) Synthesis of the sulphur-containing molecule methionine appears to be essential for viability of A. fumigatus b) Regulation of sulphur assimilation is essential for A. fumigatus virulence and c) The foremost candidate sulphur source in mammalian lungs (H2S) is gaseous, and recently identified as a novel signalling molecule in eukaryotic cells . I now wish to harness world-class clinical and scientific expertise in the field of fungal pathogenicity to identify the precise molecular source of sulphur exploited by A. fumigatus during experimental and clinical infection, with a view to designing novel antifungal therapies. OBJECTIVES 1. To define the role of methionine synthase in A. fumigatus viability I will enforce a mutational blockade upon biosynthesis of the sole methionine precursor, homocysteine, while leaving methionine synthase intact. This will decipher between essentiality of methionine biosynthesis, and essentiality of a secondary function of the methionine synthase enzyme. 2. I have eliminated cysteine and oxidized inorganic-S sources as in-host sources of sulphur. I will now address, via mutational analysis in the fungus, in-host transcriptome and transgenic mice whether methionine or H2S are exploited in the host. Having defined the S-source exploited in vivo, I will seek correlates with human disease by scrutinizing human and fungal genome sequences for SNPs associated, respectively, with human H2S production and fungal sulphur assimilation. 3. I will use A. fumigatus mutants deficient in production and assimilation of H2S to address the occurrence of, and requirement for, sulfhydration of fungal proteins during mammalian infection.

Keywords: fungal pathogen,sulphur metabolism
Nonlinear Rock and Roll - Modelling and Control of Parametric Resonance in Wave Energy Converters (ParaResWEC)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Other Widening
Action type: Marie Skłodowska-Curie actions
Countries involved: Hungary
Call: Widening Fellowships (H2020-WF-01-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 151850.88
EU funding (EUR): 151850.88
Participants: 1
Project status: CLOSED

The title of this project is ‘Nonlinear Rock and Roll – Modelling and Control of Parametric Resonance in Wave Energy Converters’. The over-arching aim is to catalyse increased research into parametric resonance (PR) within wave energy and other offshore renewable energy fields. The concept of resonance is well known in the study of wave energy converters (WECs). In comparison, PR has received virtually no attention, and is often unexpected since it is a nonlinear phenomenon not predicted by the linear/frequency domain models traditionally favoured in WEC research and analysis. Whereas normal resonance causes the oscillations of a system to grow linearly with time, PR causes an exponential increase in oscillation amplitude, and therefore has great potential to be either detrimental or beneficial to a WEC performance. For certain classes of WECs, PR can lead WEC instability and decreased performance, by transferring energy from the primary mode of motion into other modes. Alternatively, for other types of WECs designed to extract power from the parametrically resonating modes of motion, triggering PR could result in increased energy capture and represent a game-changing approach to improving WEC performance. To achieve the over-arching goal, the project focuses on the following specific objectives: 1) Demonstrate novel control techniques to either mitigate or harness PR for different classes of WECs. 2) Provide opensource tools for modelling and analysing PR in WECs, to aide the wave energy community in overcoming the barriers surrounding the advanced nonlinear methods required to investigate PR. 3) Strong communication, dissemination and exploitation activities. Providing information to the wave energy community and connections with researchers from other disciplines with relevant knowledge and experience, such as Nonlinear Dynamics, Shipping and other Offshore Engineering fields.

Keywords: wave energy conversion,nonlinear dynamics,parametric resonance,hydrodynamics,computational fluid dynamics