Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
MeAsurement of Gravitational effects on photonIc QUantum systEm (MAGIQUE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-06-01
End date: 2024-05-31
Duration (months): 24.0
Total project cost (EUR): 183600.96
EU funding (EUR): 183600.96
Participants: 1
Project status: CLOSED

The interplay between the two main pillars of physics ─ quantum mechanics (QM) and general relativity (GR) ─ has never been understood or tested by scientists, and this has become one of the most important, interesting and challenging research areas over the past decades. So far there is no experiment demonstrating how gravity affects unique quantum features, e.g. superposition and entanglement. This project is aimed to combine quantum interference and GR in a single table-top experiment using Mach-Zehnder fiber interferometry. Single photons and entanglement states will be employed to investigate how gravity alters quantum correlations and superposition of massless particles. It would be a great scientific breakthrough to demonstrate gravitational-induced effects on single photons and quantum states, paving the way for quantum gravitational lab-scale experiments. This project will push large-scale high-precision single photon interferometry to a new level, leading to the development of cutting-edge techniques from various disciplines ─ quantum photonics, precision interferometry, frequency metrology, etc. This study is timely and highly relevant to the current EU research trends, going in line with the prioritized research directions of Horizon Europe: quantum technologies and time & frequency services. This project will be implemented in the group of Prof. Philip Walther at the University of Vienna. The host group expertise in quantum control and their state-of-the-art single photon facilities perfectly complements to the Researcher Dr. Yu’s background in interferometric gravitational wave detection and macroscopic QM phenomena. This Fellowship will enable the two parties to combine their skills and achieve the major scientific goals. Furthermore, this Fellowship will greatly improve Dr. Yu’s leadership skills, strongly diversify her knowledge, establish new academic links and boost her track record that would have a significant impact on her academic career.

Keywords: precision optical interferometry,quantum photonics,gravitational physics,single photon metrology,quantum mechanics,quantum precision measurement,general relativity,fiber optics
Understanding the mechanisms of neuronal secretory autophagy (NEURO-SECRET)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 232916.16
EU funding (EUR): 232916.16
Participants: 1
Project status: TERMINATED

Neurons transmit information by connecting with other neurons over long distances through their dendrites and axons. Repeated stimulation places a high metabolic demand on these cells, leading to the accumulation of defective organelles and protein aggregates. To maintain protein homeostasis, neurons rely on constitutive autophagy to remove these damaged proteins and organelles from their dendrites and axons, targeting them for degradation. However, it is becoming increasingly clear that neurons also secrete a part of this autophagic cargo into the extracellular space. The mechanisms governing neuronal secretory autophagy are still poorly understood. The factors that determine whether autophagic cargo is degraded or secreted, as well as the precise neuronal location from which secretory autophagy occurs, remain unknown. Understanding these mechanisms is highly relevant in neurodegenerative diseases, such as Alzheimer’s disease, where the balance between degradative and secretory autophagy is disrupted. In this interdisciplinary project, I will use human iPSC-derived neurons and develop novel molecular tools to elucidate the mechanisms underlying neuronal secretory autophagy. I will employ state-of-the-art bioluminescent and fluorescent reporters to characterize this process with high spatiotemporal resolution, leveraging my experience in studying exosome release during my PhD. Furthermore, I will apply the host lab’s expertise in proximity labeling and chemogenetic relocalization to identify key regulators of neuronal secretory autophagy and explore the potential of modulating secretory autophagy in a cell model for Alzheimer’s disease. Ultimately, this project aims to provide fundamental insights into the mechanisms driving neuronal secretory autophagy and the potential for modulating this process in neurodegenerative diseases.

Keywords: secretory autophagy,amphisomes,exosomes,neurons,neurodegenerative disease
Understanding pesticide-Pollinator interactions to support EU Environmental Risk Assessment and policy (PollinERA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Research and Innovation actions
Countries involved: Denmark,Poland,Sweden,Italy,Germany,Belgium,Bulgaria,Slovenia
Call: Better understanding of routes of exposure and toxicological and ecological impacts of chemical pollution on terrestrial biodiversity (HORIZON-CL6-2023-BIODIV-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 5499473.25
EU funding (EUR): 5499473.25
Participants: 12
Project status: SIGNED

PollinERA aims to reverse pollinator population declines and reduce the harmful impacts of pesticides. It addresses the call through four objectives: SO1 filling ecotoxicological data gaps to enable realistic prediction of the source and routes of exposure and impact of pesticides on pollinators and their sensitivity to individual pesticides and mixtures. SO2 developing and testing a co-monitoring scheme for pesticides and pollinators across European cropping systems and landscapes, developing risk indicators and mixture exposure information. SO3 developing models for predicting pesticide toxicological effects on pollinators for chemicals and organisms, environmental fate, toxicokinetic/toxicodynamic, and population models. SO4 developing a population-level systems-based approach to risk and policy assessment considering multiple stressors and long-term spatiotemporal dynamics at the landscape scale and generating an open database for pollinator/pesticide data and tools. This will be achieved through developing knowledge and protocols for a broad range of toxicological testing, feeding to in silico models (QSARS, toxicokinetic/toxicodynamic, and population). Using a strong stakeholder co-development approach, these models will be combined in a One System framework taking a systems view on risk assessment and policy evaluation, including an international monitoring program. The One System framework is based on EFSA’s system ERA view, expanding on the tools used for bees to include butterflies, moths and hoverflies. The consortium partners are experts in the field needed for this development and are well-placed to facilitate the uptake of tools by European bodies to guarantee the project's future impact. Expected impacts target Destination impacts of better understanding and addressing drivers of biodiversity decline, interconnected biodiversity research using digital technologies, and understanding the biodiversity and health nexus at the ecosystem level.

Keywords: pollinators pesticides sensitivity exposure mixture toxicity toxic load monitoring risk indicators in silico model tktd population model landscape simulation policy impact systems based
Inclusion of skilled spouses in the labour market (INSKILLS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway,Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 226751.04
EU funding (EUR): 226751.04
Participants: 2
Project status: SIGNED

The rapidly changing demographic composition in Europe, characterised by an aging population and a decrease in birth rates, poses significant social and economic challenges for European states (e.g. not having a younger population in the labour force, and increased pressure on health services by the older population). Attracting highly skilled migrants (HSM) has become an essential means of addressing these challenges, and a number of countries have adopted strategies specifically targeted at attracting and retaining HSM. The project investigates the facilitators and impediments to the labour market inclusion of highly-skilled migrant spouses (HSS) through a comparative perspective of Italy and Norway. At the macro level, I ask (RQ1): What are the policies, practices, and programmes that focus on including HSS in the labour market and how well tailored are they to the needs of HSS? At the meso level, (RQ2): What is the role of employers, employment agencies and rights-based organisations in addressing the challenges that HSS encounter? Finally, at the micro level (RQ3): What career adaptability strategies do HSS develop to overcome the difficulties in finding and retaining jobs? The methods employed include semi-structured interviews with HSS, employers, employment agencies, employee associations, practitioners and political decision-makers, combined and triangulated with policy document analysis. The research findings will lead to policy recommendations as to how HSS can be better included in the labour market in Italy, Norway and Europe at large.

Keywords: skilled migration,spatial mobility,third country nationals,italy,norway,labour market
Carboxylic acids as REAcTIVE refrigerants to make heat pumps efficient (CREATIVE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-06-01
End date: 2026-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 2
Project status: SIGNED

Aiming to contribute to a substantial increase in the sustainability of thermal power plants, heat pumps, and climatization systems, the ERC-StG-REACHER is introducing new working fluids for the thermodynamic cycle underlying these systems. These new fluids are mixtures of dimers “A2” and monomers “A” undergoing a reversible dimerization reaction, A2 ⇄ 2 A, evolving instantaneously and spontaneously in the unit operations of the machine. REACHER has introduced about 200 of these reactive fluids. Among them, the family of carboxylic acids (e.g., formic, acetic, propionic acid) seems very promising as working fluids for residential heat pumps: other than owing excellent environmental properties, their use promises an outstanding 17-43% relative efficiency improvement compared to state-of-the-art heat pumps. In this context, the main objective of the ERC-PoC-CREATIVE is to perform the first step towards the realisation of a residential heat pump prototype operating with formic acid, enabling the validation of the -theoretically observed- positive chemical reaction effects. This step consists of preliminary verifying the feasible compression of formic acid with a finely controlled series of available compression technologies, using air as working fluid in the sub-atmospheric pressure conditions characterising operation with formic acid. Within CREATIVE, these results will further allow the design of a pilot operating with formic acid to test, in a future PoC, the compressors preliminarily selected and pre-tested with air, in CREATIVE. The realisation and design of the experimental setups for the formic acid compression feasibility assessment are supported by thermodynamic calculations carried out in CREATIVE, using tools developed in REACHER. This PoC is supported by the expertise of two industrial partners, and involves the Host Institution’s Technology Transfer Office which will handle IP management and explore valorisation pathways for the key exploitable results.

Keywords: reactive working fluid carboxylic acids heat pump high efficiency compressor test
Fundaments of Black Hole Spectroscopy (FundBHspec)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Denmark,United States
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-08-01
End date: 2026-07-31
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 2
Project status: SIGNED

Gravitational Wave (GW) astronomy has emerged as a fundamental field, allowing us to probe gravity in its strongest regime. Black hole (BH) spectroscopy is a highly effective method for extracting spacetime information from observed GW signals. The late-time radiation of newly formed black holes is characterized by an exponentially damped, oscillating signal. Measuring the decaying scales and oscillating frequencies — the so-called quasinormal modes (QNMs) — offers insightful information about the black hole's background. Therefore, QNMs and BH spectroscopy are crucial in astrophysics, gravitational physics, and mathematical relativity. The goal of this project is to combine mathematical relativity, numerical relativity, and astrophysics to advance the fundamental theory of BH spectroscopy. Theoretical predictions indicate that small perturbations around a black hole can drastically change its QNM spectra. Thus, in dirty environments, QNMs may deviate from the values expected for isolated BHs. Modern tools from differential geometry and high-accuracy numerical methods allow us to understand this QNM instability. This project will provide a solid theoretical foundation, which integrated into the efforts to measure QNMs, will optimise the scientific gains from BH spectroscopy in the upcoming era of high-accuracy GW astronomy. The applicant has solid expertise in the mathematical fundaments of general relativity. With the MSCA fellowship, the applicant will enhance her knowledge of fundamental aspects of BH spectroscopy thanks to the expertise of the Niels Bohr Institute (NBI), University of Copenhagen. The Strong group at NBI is composed of leading researchers in the area, providing the perfect environment for this multidisciplinary project. An academic secondment at the University of Texas at Austin will consolidate the acquired knowledge and ensure the project’s impact on key stakeholders, such as the Ligo-Virgo-Kagra collaboration and the Lisa Mission.

Keywords: black holes,gravitational waves,general relativity,conformal methods,black hole spectroscopy,gravity,quasinormal modes
Interplay of charge and energy transfer in single molecules (CATNIp)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-04-01
End date: 2025-03-31
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: CLOSED

In the pursuit to mimic highly efficient natural processes like photosynthesis in optoelectronic devices, molecule-based architectures are becoming increasingly important in reducing costs and improving energy efficiency. In these processes, intermolecular charge and energy transfer are intimately linked, however, how exactly intramolecular charge distribution, charge transfer and excited state dynamics interrelate is not fully understood, yet. Studying these fundamental processes requires tools that can control and probe both the charge state and the excited state of individual and interacting molecules simultaneously with sub-molecular spatial resolution. So far, the only way to achieve sub-nanometric spatial resolution in optical spectroscopy is to combine it with scanning tunneling microscopy, but this approach does not allow deliberately controlling the charge state of an individual molecule. CATNIp aims at combining tip-enhanced optical spectroscopy with atomic force microscopy on single molecules as well as multi-molecular complexes adsorbed on multilayer insulating films. This approach will facilitate studying the interplay of charges and excited states within such systems with atomic resolution and single-electron sensitivity. In collaboration with organic chemistry as well as theory groups, this will allow addressing fundamental questions such as how excess charges influence molecular excitons, or whether and how it is possible to tailor energy transfer between molecules by introducing localized charges within or nearby the molecular complex. In addition, CATNIp will provide me with extensive training opportunities related to gaining expertise in the field of scanning probe-based optical spectroscopy, managing my own research project, and improving my teaching skills, laying the foundation for a successful career in research.

Keywords: non contact atomic force microscopy,tip enhanced photoluminescence,tip enhanced raman spectroscopy,single molecules,charge and energy transfer,thick insulating films,electrofluorochromism
REGEN3TIQ FOR TOTAL LIFECYCLE ECOLOGICAL FOOTPRINT MANAGEMENT AND PROCUREMENT (REGEN3TIQ)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EU prize
Destination: European Innovation Procurement Awards
Action type: Recognition Prize
Countries involved: France
Call: EUIPA cat 2 (HORIZON-EIC-2023-EUIPA-PRIZES-03, 2023)
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 1
Project status: SIGNED

In Public Procurement of Innovation (PPI) public demand triggers innovation. REGEN3TIQ represents a step change in PPI process, as well as a new technology solution for fast-tracking the ecological transformation within any industry, starting with the construction sector. It is the result/product of radical innovation, triggered by successful public-private collaboration, between French SME BEAM3 and the Centre d’Expertise des Techniques de l’Infrastructure de la Défense (CETID) of the Ministry of Armed Forces of France. It has been already purchased and operationalised three times through three full blown, large-scale PPIs. Currently, it is being applied to renovation works on the entire campus of the École Polytechnique (22,000 hectares, 200,000m2 of buildings), and it will manage the total 300M (million) euro procurement budget in multiple lots. REGEN3TIQ ensures that construction and exploitation processes are aligned with quantifiable ESG (Environmental Social Governance) KPIs, with focus on green transformation, EU policy objectives, as the Green Deal, including Greenhouse Gas (GHG) emissions, resources (i.e., water) and all relevant nature-related indicators. It includes social and financial KPIs, as well as their interdependencies. It allows public buyers to improve the ability of private companies, including SMEs, to respond to calls for tenders. The application follows the 2021 EU Commission Notice on Innovation Procurement. See: https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:52021XC0706(03)&rid=6

Keywords: full blown ppis green deal digital twin open innovation taxonomy industry transformation construction built asset management decarbonisation climate neutrality renovation wave competitive
Universal interoperative sustainable agri-water management platform (UNIVERSWATER)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Clean Environment and zero pollution
Action type: Research and Innovation actions
Countries involved: Ireland,Italy,Greece,Belgium,Switzerland,Spain
Call: Knowledge and innovative solutions in agriculture for water availability and quality (HORIZON-CL6-2023-ZEROPOLLUTION-01, 2023)
Start date: 2024-06-01
End date: 2027-11-30
Duration (months): 42.0
Total project cost (EUR): 5996597.75
EU funding (EUR): 5996597.75
Participants: 15
Project status: SIGNED

Water quality and quantity are under arising pressure from agricultural activities that may cause overexploitation of natural waters and pollutants runoffs (e.g., nutrients, pesticides). These stresses are also compounded by climate change effects. To address the complex challenges of agri-water management, the UNIVERSWATER consortium will adopt a ‘system of systems’ approach by developing and improving technologies designed to optimise water resources uses in a fully integrated way. A dedicated interdisciplinary and intersectoral consortium of 15 partners from six European countries will: a) develop innovative portable and in-situ sensors for a number of parameters and pollutants (salinity, nutrients, CEC, microbiological indicators) and b) couple them with earth observation imaging and advanced explainable and robust artificial intelligence techniques, as well as c) develop cost-effective, sustainable methods based on nature-based and technology-based solutions for water remediation at the point of need and d) promote the adoption of the developed methods through pricing incentive provision. These technologies will be integrated into decision support systems (DSSs) that will be tested at three case studies tackling on-farm treatment of dairy soiled water, mitigation of soil salination through water reuse, and optimisation of fertiliser/pesticide application for freshwater preservation. Going beyond, UNIVERSWATER will upscale these local DSSs into a common platform where a suite of DSS tools can be adapted to different situations after being tailored to the local factors, thereby developing a modular, extensible and holistic universal DSS.