Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Development of an automatic process of in-house collection, storage and application of adaptive bacteria culture for fish farms. (ADAPOND)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Denmark,Estonia,Norway,Estonia,Switzerland,United Kingdom,United Kingdom,Estonia,Italy,Germany
Call:  (FP7-SME-2007-1, 2007)
Start date: 2008-09-01
End date: 2011-02-28
Duration (months): 30.0
Total project cost (EUR): 1419716.0
EU funding (EUR): 1052810.0
Participants: 13
Project status: CLOSED

Evidence from recirculation systems shows that new starters experience 30-80% loss in sales almost unavoidably in the first year during the adaption period of a biofilter, accompanied by the failure losses from fish medication and seasonal depressions counting summingly for more than €70-90M annually in Europe. Low reliability of biofilter systems are considered the main reason why people avoid entering fish farming business. Our idea is to reduce the bio-filter recovery time after failure by developing an Intelligent Biofilter Control (IBC) system. Real-time monitoring system will detect the viability and metabolic activity of the bacteria culture. At healthy period excess bacteria are extracted, prepared for storage and stored by automatic collection system. In case of biofilter failure, the stored culture will be cultivated for rapid recovery of the biofilter thereby providing increased productivity of the farm. The major barriers to overcome are: (a) Biofilter start-up and recovery processes in fish farm are slow, taking 3-6 weeks. (b) Methods of bacteria extraction and storage are designed for usage in laboratory and not providing the efficiency required for industrial applications; (c) Limited knowledge about how is the recovery performance of recultivated bacteria related to the health before collection; (d) Existing methods to assess the viability and metabolic activity of bacteria are complicated and time consuming. We intend to overcome these barriers by speeding up the recovery of a bio-filter by recultivating the stored adapted bacteria. Farm productivity will increase up to 15%; Farm supply security will improve, increasing the sales price about 5%, there is less environmental risks, and less hazard to fish health. Process for automatic extraction of the bacteria from the bio-filter, preparation for storage, and storage in industrial scale.

Keywords: lyophilization,bacteria viability,bacteria conservation,fish farm
Hydrocolloids as functional food ingredients for gut health (HYFFI)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: United Kingdom,United Kingdom,Ireland,Spain,United Kingdom
Call:  (FP7-SME-2007-1, 2007)
Start date: 2008-12-01
End date: 2011-05-31
Duration (months): 30.0
Total project cost (EUR): 1208359.4
EU funding (EUR): 936575.0
Participants: 6
Project status: CLOSED

The overall aim of the project is to realize a commercial opportunity to produce low molecular weight polysaccharides (LMWP) from alginate- and agar-bearing seaweeds for applications in food &amp; health, and wellness products by a group of SMEs. The aim will be addressed by an integrated workplan comprising 1 management activity 5 interlinked RTD workpackages, and a dissemination and exploitation activity. In the RTD programme, Cybercolloids (CC) will produce and characterize 8 novel, LMWPs from alginate and agar raw materials provided by 2 SMEs - ROKO (RO) and Hebridean Seaweed (HS). The LMWPs will be screened using batch culture fermentations with human faecal bacteria, for prebiotic activity (i.e. ability to modulate beneficially the gut microflora) by University of Reading (UREAD). The 2 most effective agar and alginate LMWPs will be selected and bulk produced by CC for validation of prebiotic activity in a feeding trial in human volunteers (University of Ulster)). The end points to be assessed will be stimulation of beneficial bacteria (bifidogenic effects), increased short chain fatty acid production, beneficial effects on stool formation, and improvements in gut barrier function (assessed by an in vitro method). Additionally, benefits of the LMWPs towards plasma lipid profiles and blood glucose levels will be assessed. Alongside the human study, a detailed investigation of the effects of the selected LMWPs in an in vitro model of the human colon will be conducted by UREAD to provide supporting evidence for beneficial effects on bacterial types and activities in the colon. RO and HS in conjunction with CC will implement LMWP technology transfer and scale-up to facilitate production at an industrial scale. Subsequently, another SME Marigot Ltd, will provide a route to market and in conjunction with RO, HS and CC will exploit, with respect to the health and wellness sector, the relevant knowledge provided on the efficacy of novel LMWPs from alginate and agar.

Keywords: functional foods,agar,alginates,health benefits,gut health,prebiotics
ENRICHMENT OF AQUACULTURE IMPLANTS BY INTRODUCTION OF NEW MARINE SPECIES FROM THE WILD TO BREEDING. (ENRICH)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Italy,United Kingdom,Israel,Italy,Croatia
Call:  (FP7-SME-2007-1, 2007)
Start date: 2008-12-01
End date: 2011-05-31
Duration (months): 30.0
Total project cost (EUR): 1560171.5
EU funding (EUR): 1188880.0
Participants: 11
Project status: CLOSED

We propose a two years work, aiming at optimising sea urchin Paracentrotus lividus rearing, in order to enrich pre-existing aquaculture farms (based on sea bass, bream, and/or different bivalves) . Sea urchin breeding will be performed starting from adult specimens obtained from capture. Sea urchin roe (gonads) are first class food and are worldwide commercialised. This project arises from the increasing demand of sea urchin roes and is addressed to the feasibility of sea urchin aquaculture, broodstock and gonad improvement. In the last fifteen years, the aquaculture of sea urchin has been carried out by non-European factories, mainly in Japan, USA and Canada. Unsexed whole sea urchins or their processed gonads are shipped primarily to Japanese markets and to markets in France, Belgium, Greece, Italy and Turkey. The demand in these European Countries is at present partially fulfilled by a high fishing pressure on wild sea urchins, that in some areas (France, Greece) are at risk and protected species. A number of European and ICPC SMEs, dealing with aquaculture, are strongly interested to carry on a research focused at 2 main objectives: 1-to insert sea urchin aquaculture in their activities, in order to enrich and diversify their production, that is already going on with different marine species. 2- to obtain an environmentally friendly expansion of their activity, in order to increase sustainability and prevent environmental impact. The involved SMEs aim at obtaining know how and possibly patents to be invested in their activity, and need RTD activities and training of operators for overcoming problems and enhance competitivity.

Keywords: breeding,roe improvement,broodstock improvement,waste recycling,environemntally friendly
Development of novel sintered sphere filtering technique for moulding opaper pulp to reduce energy consumption and environmental effects of plastic (SINFILTRATE)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: United Kingdom,France,United Kingdom,United Kingdom,Spain,Germany,Sweden,United Kingdom
Call:  (FP7-SME-2007-1, 2007)
Start date: 2008-07-15
End date: 2010-10-14
Duration (months): 27.0
Total project cost (EUR): 1279463.96
EU funding (EUR): 994046.0
Participants: 9
Project status: CLOSED

China poses a major competitive threat to the European market for the manufacture of products for packaging. Moulded Paper Products (MPP) from China are up 20% cheaper than the equivalent EU products. Due to continued increase in prices there is a need for the EU industry to reduce cost affiliated with low energy efficiencies. A major portion of recovered fibre is sourced from local SMEs such as waste paper merchants, waste management companies and corrugated case manufacturers. The recovered paper market will be directly impacted through potentially higher demand. Demand from China for recovered fibre has pushed prices high. Exports globally estimated at over 13 million tonnes per annum (expected to increase by around 18 million by 2009) are used mainly for MPP manufacturing, which are subsequently exported back to Europe. Estimated growth volumes for existing and new markets, show that increasing usage of recovered fibre will be restrained, unless the industry can move forward on the following key issues: • Improvement in the ability to produce cost competitive products • Step change in the aesthetic characteristics of products, at competitive prices • Migration towards utilisation of post- consumer recovered fibre The Solution. The proposed project aims to develop a novel process for producing moulded paper products more energy efficiently with better complexity in design. This developed technology will open the way for more applications of MPP across further industries, such as to replace plastic packaging used for consumables, ‘non critical’ parts in automotive and plastic bottles.

Keywords: energy reduction,environmental impact,paper,plastic
Metagenomics for bioexploration - Tools and application (METAEXPLORE)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Life sciences, biotechnology and biochemistry for sustainable non-food products and processes
Action type: Collaborative project
Countries involved: Netherlands,Denmark,Sweden,United Kingdom,Netherlands,France,Germany,Germany,Belgium,Finland,Belgium,Italy,Slovenia,Argentina,Netherlands,France,United Kingdom
Call:  (FP7-KBBE-2007-2A, 2007)
Start date: 2009-05-01
End date: 2014-04-30
Duration (months): 60.0
Total project cost (EUR): 8065047.0
EU funding (EUR): 5999991.0
Participants: 18
Project status: CLOSED

This proposal will (further) develop and apply metagenomics tools to access the enzymatic potential borne in the cryptic biota of selected natural habitats, in particular target soil-related and aquatic ones. In the light of the environmental relevance of chitins and lignins (as natural compounds recalcitrant to degradation) and halogenated aliphatic and aromatic compounds (anthropogenic recalcitrant compounds), the enzymatic activities that we will target are functions able to degrade these compounds. A database of gene functions will be established and maintained. Next to its great relevance to environmental biotechnology including bioremediation, a spin-off of the work will be the discovery of novel biocatalytic functions of industrial relevance. We will in particular address the catabolic potential that is encoded by the mobilome, the collective pool of mobile genetic elements in the microbiota. We will further apply high-throughput (454-based) sequencing to rapidly unravel the metabolic complement in this mobile gene pool. The project brings together a suite of 15 contractors across Europe, encompassing 21 laboratories spread over 11 copuntries and including 4 SMEs. Most of the partners are renowned laboratories which have vast experience in metagenomics of environmental samples, biotechnology, enzymology, bioinformatics, the mobilome, waste management and bioremediation and enzyme production.

Keywords: environmental metagenomics - mobilome - enzymes for waste and pollutant mitigation - biocatalysis - protein engineering
Novel Technologies for Surveillance of Emerging and Re-emerging Infections of Wildlife (WILDTECH)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Collaborative project
Countries involved: United Kingdom,United Kingdom,Germany,Netherlands,Germany,Greece,Sweden,Croatia,United Kingdom,Canada,France,United Kingdom
Call:  (FP7-KBBE-2007-2A, 2007)
Start date: 2009-07-01
End date: 2013-12-31
Duration (months): 54.0
Total project cost (EUR): 8961377.33
EU funding (EUR): 5996822.0
Participants: 14
Project status: CLOSED

With the increasing impact of mankind’s activities on the natural environment, disease naturally harboured by wild animals, both within the geographical limits of the EU and elsewhere, are becoming increasingly significant both for public health and health of livestock, in addition to having direct concerns for wild animal species. We are proposing a project which will combine (i) technological development to enable high through-put array-based screening of samples from a wide variety of wild animals with (ii) surveillance of terrestrial, aerial and marine wild animal species within Europe and from countries which act as portals of disease entry into the EU, (iii) epidemiological analysis and risk assessment using data generated during the project and from other sources, and (iv) development and proposal of a model framework for disease surveillance within Europe developed in parallel with the burgeoning systems in North America. The proposal will place the EU at the centre of wildlife disease surveillance and also enable the translation of high throughput array-based technologies into human and veterinary medicine.

Keywords: wildlife,infectious disease,surveillance,monitoring,microarray,serology
Design and development of REAlistic food Models with well-characterised micro- and macro-structure and composition (DREAM)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Fork to farm: Food (including seafood), health and well being
Action type: Collaborative project
Countries involved: France,France,United Kingdom,Hungary,Italy,Spain,France,United Kingdom,Hungary,Ireland,France,Slovenia,Finland,Netherlands
Call:  (FP7-KBBE-2007-2A, 2007)
Start date: 2009-05-01
End date: 2013-10-31
Duration (months): 54.0
Total project cost (EUR): 8521333.2
EU funding (EUR): 5995786.0
Participants: 21
Project status: CLOSED

DREAM a trans-disciplinary partnership involving two multinationals and nine countries will develop realistic, physical and mathematical, food models for use as standards to be exploited across all major food categories to facilitate development of common approaches to risk/benefit assessment and nutritional quality in food research and industry. These models will enhance knowledge on process-structure-property relationships from the molecular to macroscopic level and facilitate creation of generic food matrices with functional and nutritional properties based on tailored microstructure. To address as wide a range of food products as possible, 4 generic structure groups will be used representing plant-based foods; meat; dairy and bakery products; for each, the most relevant types of products will be selected using criteria including structural characteristics and industrial and societal needs, ensuring that benefits/risks, economic importance and sustainability are taken into consideration. The model development will be conducted in close collaboration with food manufacturers through a specification-based approach. The objective of the mathematical approach is to realise a complete dynamic description of food processing using an innovative strategy exploiting most recent advances in cognitive and complex system sciences to allow the generalised methodologies to be extended to other food products. Models and protocols developed within DREAM will be disseminated by expert partners via existing channels (EFFoST, ETP and national platforms, CIAA and national federations, EFSA, national regulatory bodies) to be used by scientists, SMEs and multinationals to improve nutritional quality and benefit-risk management of the food chain. The involvement of ETP Food for Life will ensure the approach is extended to all foods by 2015. Training for young members of DREAM will equip them with scientific and other complementary skills necessary for career development within the ERA.

Keywords: realistic food models,mathematical knowledge integration,generic approaches,industrial know-how,structure,function,process,safety and nutrition,standardisation,risk/benefit assesment
From Sequence to Consequence - Tools for the Exploitation of Livestock Genomes (QUANTOMICS)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Collaborative project
Countries involved: Denmark,Norway,Germany,United Kingdom,Spain,Italy,Finland,Germany,Israel,Greece,Denmark,Australia,United Kingdom,United Kingdom
Call:  (FP7-KBBE-2007-2A, 2007)
Start date: 2009-06-01
End date: 2013-11-30
Duration (months): 54.0
Total project cost (EUR): 8179086.7
EU funding (EUR): 5999671.0
Participants: 18
Project status: CLOSED

QUANTOMICS will deliver a step-change in the availability of cutting edge technologies and tools for the economic exploitation of livestock genomes. We will provide the tools to identify rapidly the causative DNA variation underpinning sustainability in livestock and for industry to exploit high-density genomic information. Our adaptable quantitative and genomic tools each based on cutting-edge technologies and valuable in itself, will together form a powerful integrated pipeline with wide application. To deliver these outcomes we will; i) use comparative genomics to annotate putatively functional features of the genomes of the EU’s key farmed animal livestock species; ii) enhance existing molecular genetic tools (to include copy number variation, CNV); iii) deliver computationally optimised tools for genome-wide selection (GWS) to include CNV; iv) apply these tools to important health and welfare traits in commercial populations of dairy cattle and broiler chickens, determining the benefits and constraints; v) use hyper-parallel resequencing of DNA within identified genomic features underlying loci of large effect in significant numbers of animals to catalogue variation; vi) develop new visualisation tools to make this variation publicly available via the Ensembl genome-browser; vii) develop tools to prioritise the likely functionality of identified polymorphisms; viii) validate the utility of the putative causative haplotypes within commercial populations; ix) test the potential advances from combined GWS and gene assisted selection in breeding programmes; x) explore new methods to manage molecular biodiversity; xi) assess the implications of these new tools for breeding programme design, and xii) disseminate results of the project achieving major competitive, animal health and welfare impacts across the EU livestock industry and ultimately consumers. QUANTOMICS will have wide application in all farmed species and leave a legacy of resources for future research.

Keywords: genomics,cattle,chicken,pig,sheep,breeding,health,welfare,selection
Novel high-performance enzymes and micro-organisms for conversion of lignocellulosic biomass to bioethanol (NEMO)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Life sciences, biotechnology and biochemistry for sustainable non-food products and processes
Action type: Collaborative project
Countries involved: Finland,Sweden,Netherlands,Belgium,Sweden,Germany,Switzerland,France,Italy,Netherlands,Slovenia,Italy,Netherlands,Sweden,Germany,Germany
Call:  (FP7-KBBE-2007-2A, 2007)
Start date: 2009-05-01
End date: 2013-04-30
Duration (months): 48.0
Total project cost (EUR): 8098596.0
EU funding (EUR): 5898000.0
Participants: 21
Project status: CLOSED

The NEMO project provides novel efficient enzymes and microbes for 2nd generation bioethanol production. It generates through metabolic engineering and mutagenesis & screening approaches robust yeast strains that have a broad substrate range and can (co-)ferment C6 and C5 sugars to ethanol with high productivity (rate and yield), and that are significantly more stress tolerant, i.e. inhibitor, ethanol and thermotolerant than the current S.cerevisiae strains used in ethanol production. The NEMO project also identifies and improves enzymes for hydrolysis of biomasses relevant for Europe. Novel enzymes are identified and improved through various approaches, based on screening, broad comparative genomics analyses, and protein engineering. These efforts will generate more thermostable enzymes for high temperature hydrolysis, more efficient enzymes for hydrolysis of the resistant structures in lignocellulose such as crystalline cellulose and lignin-hemicellulose complexes, enzymes with reduced affinity on lignin, and efficient thermo and mesophilic enzyme mixtures that are optimised and tailor-made for the relevant biomasses for Europe and European industry. These novel biocatalysts are tested in an iterative manner in process relevant conditions, including also pilot-scale operations, which ensure that the novel enzymes and microbes will be superior in real process conditions. Furthermore, optimal enzyme, microbe and process regime combinations are identified, providing basis for the development of the most economic and ecoefficient overall processes. The impact of the NEMO project on 2nd generation bioethanol production is significant because it provides most realistic but widely applicable technologies that could be exploited broadly by European industry. Its impact goes also much beyond bioethanol because NEMO provides technology improvements that are directly applicable and crucial for efficient and economic production of also other biofuels and bulk chemicals.

Keywords: bioethanol,lignocellulose,enzymatic hydrolysis,thermophilic enzymes,pentose fermentation,stress-tolerant microbes,s.cerevisiae,agrowaste,energy crops,wood,sugar cane bagasse