Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Signpost - the world’s first scalable model for adaptable community-driven information services helping people amidst life-threatening crises sustainably. (SIGNPOST)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EU prize
Destination: European Prize for Humanitarian Innovation
Action type: Recognition Prize
Countries involved: Germany
Call: The EU Prize for Humanitarian Innovation (HORIZON-EIC-2023-HUMANITARIAN-PRIZES-05, 2023)
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 1
Project status: SIGNED

Signpost is the world’s first scalable model for community-driven information services — deployed digitally in over 20 countries on five continents in 13 languages. Signpost’s mission is to help asylum seekers, displaced people, neglected communities and victims of violence access the information they need. Signpost focuses on the agency and dignity of communities by providing access to the full breadth of options amidst life-threatening crises. Signpost is pioneering a revolutionary standard for information — one that is up-to-date, cross-cutting, interagency, and multi-sectoral. It delivers the information that communities say they need on the platforms they use in languages they understand, maintaining two-way dialogue. Signpost is operating at a global scale and continues to grow. Signpost has reached 73M people with community-driven content through social media and has over 11M unique users — registering over 500,000 new users a month. Signpost is expanding into 10 new countries by the end of Q1 2024. Signpost is best understood as the confluence of three elements: 1) an innovative project that reaches scale and delivers the best results, 2) an inclusive consortium of leading international and local NGOs and private sector companies, partnering for deep contextual knowledge and local empowerment, and 3) an evidence-based model for community-driven information programs, with a suite of materials to carry out quality programs at the global scale. Signpost is led by the International Rescue Committee in collaboration with Internews, Mercy Corps and technology partners Google.org, Cisco and Zendesk. Signpost has proven concept, sustainability, impact, efficiency and scalability — and is now poised to change the architecture of humanitarian information programming worldwide.

Keywords: humanitarian innovation,community driven,crisis communication,information standard,social media,humanitarian,localisation,digital,data driven,safety
Abstraction. Unlocking meaning from experience, through language. (ABSTRACTION)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-06-01
End date: 2027-05-31
Duration (months): 60.0
Total project cost (EUR): 1392265.0
EU funding (EUR): 1392265.0
Participants: 1
Project status: SIGNED

Words, language's building blocks, are labels that define different types of categories. Some words define categories of concrete entities (cats, tables) while others define abstract entities (legacy, empathy). Some words define generic categories that encompass many different entities (vehicles, art) while others define more specific ones (sport cars, Impressionism). To unlock meaning from experience, we construct different types of categories through mechanisms of abstraction. Concreteness and specificity are the two variables that support abstractions. However, when investigating the mechanisms and effects of abstraction, scholars from different fields typically focus only on specificity or only on concreteness. Relying on different and partial definitions of abstraction, the debate across scientific communities is impaired and the theoretical development is jeopardized. This is also due to the fact that human-generated resources to measure specificity do not exist. The ABSTRACTION team will collect specificity data for thousands of words in 2 languages (English and Italian) through an innovative gamification technique. Using this data and other lexical resources, we will run extensive statistical analyses aimed at explaining how specificity interacts with concreteness in: - Thought, to explain contrasting findings that have been previously attributed to concreteness alone - Language, to construct texts that are optimally clear and informative for the target readerships - Creativity, to construct effective metaphors in different contexts ABSTRACTION will explain how word specificity and concreteness enable us to unlock meaning from experience and achieve the higher-order generalizations on which much of our thinking and talking relies. This is a hot topic in cognitive science, where the grounding of abstract concepts is an open question, and in AI research, where it is still unknown how machines may construct and use concepts in the way humans do.

Keywords: word meaning semantic categorization concreteness effect corpus linguistics language use communicative effects metaphors linguistic creativity
Novel photocatalysts based on ferroelectric high entropy oxide-metal nanoparticle composites (FHEOAG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Slovenia
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-11-01
End date: 2026-10-31
Duration (months): 24.0
Total project cost (EUR): 155559.36
EU funding (EUR): 155559.36
Participants: 1
Project status: SIGNED

Ferroelectric high entropy oxides (FHEOs) are a novel type of ferroelectric material with the simultaneous existence of configurational entropy and internal ferroelectric polarisation. These effects combined with intrinsic lattice distortion and uneven electron-cloud distribution of high entropy oxides can lead to the generation of multiple active sites with improved separation of charge carriers, significantly impacting different photocatalytic reactions, such as pollutants degradation and water splitting. Furthermore, the visible-light-driven photocatalytic activity of FHEOs can be secured by the decoration with plasmonic metal nanoparticles (MNPs), efficiently harvesting visible light due to their localised surface plasmon resonance (LSPR). Thus, our strategy is to synthesize an entirely new FHEO and decorate it with plasmonic MNPs to produce a novel material with improved charge separation and visible light absorption, which will contribute to a major step forward in the catalysis field. The produced materials will be fully characterised and the photocatalytic efficiency will be evaluated over the degradation of pollutants present in wastewater and in the water splitting process.

Keywords: high entropy materials,nanostructures,photocatalysts,ferroelectric materials,plasmonic metal nanoparticles
Thermal management enabling longevities in (electric) Energy Transformative Technologies (ThermEnTrans)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom,Poland,Greece,Norway,Ireland,Netherlands,France,United States,Canada,Brazil,India,Japan,Switzerland,South Africa
Call: MSCA Staff Exchanges 2024 (HORIZON-MSCA-2024-SE-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 1796442.86
EU funding (EUR): 1753500.0
Participants: 20
Project status: SIGNED

Modern devices require energy transition technologies to power them. These include electric vehicles, photovoltaic panels, and high-speed microprocessors. However, our insatiable demand for speed and power means that energy storage devices are becoming larger with higher capacity. Such unregulated scale-up of devices, comes with increased risks of over-heating and fires. Therefore, ensuring system longevities requires further understanding of the effect of scale-up on heat dissipated. This will help us design systems to remove this heat, which enables longevities improving energy utilisation and minimising waste. Liquid-gas or solid-liquid phase-change thermal management offers an alternative to single-phase cooling/heating. This work builds on our previous RISE project (EC-H2020-RISE-ThermaSMART-778104) that upskilled over 50 students to obtain doctoral and masters degrees, and led to over 75 publications. ThermEnTrans will focus on understanding and developing the necessary multiscale frameworks to scale-up phase-change thermal management systems enabling immediate take-up by industry. This is via collaboration between 16 top universities from Europe, Asia, Africa, North America and South America, and 4 EU industries with expertise in precision experiments, micro-fabrication, theoretical modelling, numerical simulations, batteries and cooling systems design. Our collaboration will enable knowledge transfer, access to exclusive facilities (at MIT, Georgia Tech, York Toronto, TIFR Bangalore, Kyushu) and training of around 50 doctoral researchers in latest experimental, modelling, design and scale-up methods. Besides regular meetings, we will have annual workshops (Thessaloniki, London, Fukuoka and Atlanta) and training schools (Edinburgh, MIT, Warsaw, Bangalore and Pretoria). This will consolidate the EU’s position at the forefront of cutting-edge research in this crucial area and promote long-sustaining collaboration between academia and industry.

Keywords: energy transition,phase change,thermal management,cryogenics,manufacturing,environment,sustainability
Dissecting the body-wide spatio-temporal organisation of human resident T helper cells (ORGANise-T)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and I mmunotherapy
Panel description: The immune system , related disorders  and their mechanisms , biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases , innovative imm unological tools and approaches , including  therapies
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 1997943.0
EU funding (EUR): 1997943.0
Participants: 1
Project status: SIGNED

T helper cells represent a heterogeneous population of immune cells that are critical for host defense and, if dysregulated, for pathologies such as autoimmunity and allergy. T cell responses take place in peripheral tissues. Yet, insights into their identity and regulation stem almost exclusively from investigations of circulating blood, which comprises only 2% of the total human T cell population. Accordingly, current immunomodulatory drugs act systemically, but lack tissue specificity. Despite progress in the temporary suppression of chronic inflammatory diseases, they still fail to be curative. This project aims to address this unmet medical need by generating fundamental insights into the dynamic compartmentalisation of human tissue resident T helper cells across space and time. I have established a surgical patient cohort for the collection of multi-organ tissue samples and a cohort of patients after allogeneic hematopoietic stem cell transplantation (allo-HSCT) that enables tracking T cell tissue entry and exit over time in matched organs by single-cell chimerism analysis. Using multimodal state-of-the-art technologies and specialised high-throughput cell culture methodologies in these two unique patient cohorts, the project will dissect 1) the phenotypic, functional and transcriptional identity and molecular regulation of human resident T helper cells across tissues, 2) the compartmentalisation of their antigen specificities across tissues, 3) the dynamics of tissue entry, persistence and exit for distinct T helper cell types in space and time, and will then 4) exploit chimeric host/donor T cell-tracking to gain novel insights into the cellular and molecular pathways underlying graft-versus-host disease. Overall, ORGANise-T will establish first-of-its-kind insights into the spatio-temporal dynamic organisation of human T cell immunity in tissues. This will bring the next generation of immunotherapies to the level of tissue specificity.

Keywords: t helper cells,tissue resident t cells
Stroke Alert (S-Alert)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499999.0
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Stroke-Alert's (S-Alert) vision is to change the standard of care, shifting from care to cure. Our mission is to develop the first medical device that can alert an impending stroke based on biological mimicry. Stroke is the leading cause of disability, with a billion people at risk. Treatment is effective if given in time. Unfortunately, most people arrive too late. S-Alert intends to provide timely stroke detection to enable early intervention and prevent disability. S-Alert’s innovative breakthrough system can monitor flow, detect a change, and alert in time for responsive care (within the golden hour). Our entry point is hospital intensive care units (€14B TAM). S-Alert has scalable markets such as: 1) Hospitals: Once penetrating the ICU, the hospitals will use the device for high-risk patients in the emergency room, departments, and operating theatres. 2) Hospital at home (assisted living): S-Alert can be used for patient monitoring at home, such as home hospice for oncology patients with a high stroke risk. Avertto’s team has the capability and is highly motivated to implement S-Alert and bring it to the market. The management and the team have the technological and marketing experience to face the risks. The team has prepared precaution and mitigation plans for the project’s foreseen risks. Avertto currently enjoys close relationships with the relevant stakeholders to implement the action, including KOL (Marc Ribo Val d’Hebron), strategic partners (Medtronic), and consumers (nursing homes in France). There is currently a large unmet need for early Stroke detection: Stroke is the leading cause of disability worldwide and a main cause of death. Over six million people die annually from a stroke. Avertto's engagement with Deep-Tech is supported by its employees and management team representing the medical, algorithms/AI, and hardware knowledge.

Keywords: continuous telemonitoring for stroke,telemedicine,early intervention,reducing stroke morbidity and mortality,automated alert system for stroke for at risk individuals
Wildfire Intelligent Large-scale Drone for Hazard Observation, Prevention, Protection, and Efficient Response (WILDHOPPER)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 5400000.0
EU funding (EUR): 5400000.0
Participants: 1
Project status: SIGNED

The WILD HOPPER project represents a transformative leap in wildfire management technology, addressing the urgent need for enhanced firefighting capabilities across Europe. This pioneering initiative utilizes heavy-duty multirotor drones with a proprietary water mist jet system, designed to revolutionize wildfire response. The WILD HOPPER can operate continuously, including during night-time and adverse weather conditions, overcoming the limitations of traditional manned aircraft which are restricted to daylight operations. Featuring a payload capacity of 600 liters, the drone employs advanced thermal engines and a patented water mist technology to deliver precise, high-penetration water dispersion, optimizing fire suppression efficiency. Significantly, WILD HOPPER eliminates risks to human lives by allowing platform management from a secure ground base, thus safeguarding personnel. Compared to conventional aerial firefighting methods, WILD HOPPER is notably more cost-effective, making it feasible for small and medium regional bodies to deploy their own rapid-response resources. The simplicity of its design translates to reduced ownership costs, while its capacity for swarm operation enables coordinated deployment of multiple units to enhance overall effectiveness. This innovation aligns with the European Union's strategic objectives as outlined in Horizon Europe, particularly under the EU Civil Protection Mechanism (Article 10 of Regulation (EU) 2019/420), which advocates for advanced technologies that improve disaster response and resilience. By addressing these priorities, the WILD HOPPER project promises substantial benefits for Europe, including improved wildfire management, reduced economic impacts, and enhanced safety for communities and ecosystems.

Keywords: firefighting,uav,drones,swarming
New physics from a precision concordance model of the radio sky (UnifySky)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2025-COG, 2025)
Start date: 2026-12-01
End date: 2031-11-30
Duration (months): 60.0
Total project cost (EUR): 2250330.0
EU funding (EUR): 2250330.0
Participants: 1
Project status: SIGNED

My proposal is to build an unprecedentedly accurate and complete model of the radio sky, and then use it to solve several important problems in astrophysics and cosmology. The model will incorporate improved analyses of existing data, plus new, precisely-calibrated observations from a novel horn antenna telescope that I will build. Using advanced statistical techniques capable of handling millions of parameters – implemented in my world-leading Hydra code – I will disentangle the many physical components of the sky, along with troublesome instrumental effects that have clouded our view until now. This will transform radio cosmology by removing some of the most important limitations of experiments like the Hydrogen Epoch of Reionization Array (HERA) and Square Kilometre Array (SKAO), which seek to observe signals from neutral hydrogen (the 21cm line) around the first stars and galaxies. It will also directly address two major observational anomalies – the ARCADE-2 excess and EDGES absorption feature – that may be the first signs of new physics. The result will be a unique “concordance” model of the radio sky that connects our understanding of radio emission all the way from the early Universe to the present day. This groundbreaking model will include new data from HERA and the MeerKAT Large Area Synoptic Survey, which are the most sensitive surveys of their kind. It will also include detailed corrective modelling of instrumental effects in widely-used datasets such as the Haslam 408 MHz map. My novel horn antenna will provide a new and much-needed “absolute” calibration reference, as well as directly observing the sky-averaged 21cm signal, a crucial ingredient in understanding early galaxy formation. The major outcomes will be best-ever measurements of Galactic synchrotron physics, the cosmic radio background, and the sky-averaged 21cm line, plus vital new constraints on Cosmic Dawn and dark energy from 21cm fluctuations at high and low redshift respectively.

Keywords: cosmic dawn,radio background,21cm global signal,diffuse radio emission
Mechanisms of proliferation-independent mutation (CLOCK)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-05-01
End date: 2027-04-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

DNA damage contributes to the ageing of tissues and causes mutations that drive cancer. However, the molecular mechanisms underlying many mutational processes are not understood, and neither is how much they contribute to disease. With a powerful new technology, I propose to close these major gaps for common ?clock? mutations of unknown origin. The recent genome sequencing revolution has revealed unexpected diversity in mutational patterns. One pattern in particular is intriguing as it behaves as a molecular ?clock?: the number of mutations increases over time and correlates with age. Although the textbook view of mutagenesis is that cell division is required to convert DNA damage into point mutations, surprisingly, non-dividing cells like neurons also accumulate ?clock? mutations as a function of time, indicating that ?clock? mutations arise without genome replication. Understanding how cells mutate independently of proliferation?and thus challenging the current paradigm of mutagenesis?is a fundamental question that has been hindered because assays to measure mutation require cell division. Excitingly, I have overcome this major obstacle by establishing a powerful strategy to sensitively detect mutations in single cells, genome-wide. My group will combine this approach with targeted genetic manipulations in cells and mice to answer two central questions. (1) How do cells mutate independently of proliferation? (2) What drives these mutations in tissues? My novel insights into endogenous DNA damage from mouse genetics and genomics, combined with the innovative sequencing strategy that I have established, uniquely position me to answer these long-standing questions. Together, the work proposed here will reveal the molecular mechanism(s) underlying the most common mutational process in humans: ?clock? mutation. The methods, data, and insights from these groundbreaking studies will directly impact cancer research and uncover novel sources of DNA damage during aging

Keywords: mutagenesis,endogenous dna damage,dna repair,sbs5