Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Human serum albumin nanoparticles for synergistic chemotherapy and oligonucleotide therapy against oncogenic lncRNAs in lung cancer (syRNAlb)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-08-01
End date: 2028-07-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Lung cancer remains the most frequently diagnosed and most lethal cancer, making this disease a huge socio-economic challenge. Therefore, new effective therapeutic approaches are urgently needed. Long non-coding RNAs (lncRNAs) are versatile molecules that influence crucial pathways in cancer progression. RP3-340N1.2 is a poorly investigated but highly overexpressed lncRNA in lung cancer, suggesting it plays a pivotal role in its progression. The fellow will investigate the role of RP3-340N1.2 in lung cancer and its application in targeted therapy. SyRNAlb aims to overcome the existing limitations of lung cancer therapy by developing clinically translatable human serum albumin-based nanoparticles (HSA NPs). HSA NPs will release therapeutic oligonucleotides and chemotherapeutics in cells to synergistically reduce the lung cancer burden whilst avoiding the development of drug resistance and detrimental side effects. SyRNAlb will support Horizon Europe's mission on cancer by increasing the knowledge in lung cancer biology, specifically by characterising the role of the oncogenic lncRNA RP3-340N1.2. Additionally, the fellow will address the Translational European Challenge by developing a cutting-edge therapy based on a novel, stable and scalable albumin nanoformulation that co-delivery chemotherapeutics and oligonucleotides against RP3-340N1.2. The knowledge generated in syRNAlb will expand our limited understanding of the role of RP3-340N1.2 in lung cancer progression and promote the development of an effective treatment. Furthermore, the expertise and tools generated can be customized for other diseases and other target lncRNAs. This ambitious multidisciplinary project will promote the candidate's career as a future leader by learning not only novel molecular and cellular biology techniques (in 2D and 3D cultures), nano-bioengineering and bioinformatic techniques, but also training in leadership and clinical transfer.

Keywords: nanomedicine,albumin nanoparticles,long non coding rna,non coding rna,lung cancer,combination therapy,oligonucleotide therapy
SUPERCONDUCTING EUROPEAN QUANTUM PILOT LINE (SUPREME)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Framework Partnership Agreement
Partnership: CHIPS (JU-JTI)
Countries involved: Finland,Netherlands,Germany,France,Czechia,Italy,Spain,Austria
Call: Quantum Chip Technology for stability Pilots (HORIZON-JU-Chips-FPA-QAC-1, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 23
Project status: SIGNED

SUPREME will bring superconducting quantum fabrication technologies to a yet unforeseen level in Europe, by developing key superconducting processes to become stable, repeatable, and with high yield. SUPREME will implement a superconducting stability pilot line to address the need for superconducting components and systems for quantum computing, quantum communication, and quantum sensing. Significant increases in both technology and manufacturing readiness levels will be achieved thanks to systematic quality assurance procedures and complementary expertise of leading European innovators in SUPREME consortium. The technologies will be available for European users, including start-ups, scale-ups, SMEs, large companies, RTOs and academia through PDKs and a centralized service office. A European pilot line enables European companies to innovate and develop IP in Europe, building a basis for long term economic growth, and to secure European sovereignty and autonomy in superconducting quantum technology. SUPREME will actively participate in the development of the European innovation network and of a European business model for piloting services by collaboration with the Design platform and the other quantum pilot lines. With increased global regulations and export control restrictions, it is of outermost importance that Europe has capabilities and know-how and IP within Europe to develop and fabricate critical quantum technologies. SUPREME stability pilot line will prepare for technology transfer of the developed technology and processing IP to volume foundries to enable wide industrialization of the developed technologies within Europe.

Keywords: superconducting technology,quantum chips,stability pilot line
Interindividual variability in the structural and functional organization of human visual cortex (INVISION)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-11-18
End date: 2026-11-17
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: SIGNED

Our brains are equipped with extraordinary degrees of structure, typically found in similar cortical locations and with similar topography across individuals, indicating a common architectural design of sensory information representation. Despite the striking similarity of this topographic organization across people, recent investigations have revealed compelling evidence of interindividual differences in the topography of early visual areas’ retinotopic maps as well as the size and spatial location of higher-order visual areas, challenging the notion of consistent mapping even at the earliest cortical processing stages. Revealing what factors determine interindividual differences in retinotopic maps and functionally selective clusters promises a pathway toward understanding why our visual system is organized the way it is. Through INVISION, I will determine the biological basis and experiential processes underlying interindividual variability in the functional organization of the human visual cortex and their functional significance for visual behavior. I will achieve these goals by expanding my skill set to cover varied magnetic resonance imaging modalities and behavioral data analyses under the supervision of Prof. Martin Hebart, a renowned researcher in vision sciences and particularly well-known for developing and utilizing large-scale functional datasets for understanding human visual perception, with additional support from Dr. Evgeniya Kirilina, with expertise in the analysis of diffusion-weighted imaging data. By expanding my theoretical knowledge in vision sciences through one-on-one training with Prof. Hebart, I aim to become an independent vision scientist with deep knowledge of human vision at the structural, functional, computational, and behavioral levels.

Keywords: vision retinotopic mapping interindividual variability mri
Loneliness, Emotions, and Regulation: Understanding Institutions through Privacy (LONERS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Austria
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-06-01
End date: 2031-05-31
Duration (months): 60.0
Total project cost (EUR): 2499987.0
EU funding (EUR): 2499987.0
Participants: 1
Project status: SIGNED

LONERS addresses the growing public health and security concern of loneliness, which often leads to feelings of isolation, anxiety and despair. As loneliness becomes more prevalent in modern society, its social and political implications expand. However, loneliness can also evoke positive emotions such as calm, self-reliance and empathy, highlighting the complexity of this emotional landscape. Understanding this spectrum of emotions is crucial for addressing loneliness effectively in both individual and societal contexts. LONERS examines the interplay between loneliness, privacy and emotion, with the goal of reconceptualizing how institutions recognize and meet the emotional needs of citizens. The project goes beyond traditional approaches to privacy in data protection and surveillance, identifying key moments where institutions can intervene to support individuals while respecting their privacy. By systematically exploring how personal emotional experiences of loneliness intersect with societal values, norms and expertise, LONERS aims to provide a conceptual framework to better follow the balance between regulating citizens’ well-being and respecting their privacy. Through an innovative, multi-method analysis—including life-story interviews, a discourse analysis of personal blogs and text-as-data-supported reviews of expert debates and policy discussions—LONERS will bring unique empirical insights about the diverse emotions associated with loneliness. By reframing the scholarly discourse, LONERS will conceptualise the critical role of emotions in shaping institutions. This work will contribute to broader debates about how public institutions navigate the balance between understanding and acting upon intimate information. This research will significantly advance our understanding of loneliness and privacy, while paving the way for future explorations into social cohesion and welfare, opening new avenues for research.

Keywords: context,discourse,emotions,loneliness,public policy
Shape Memory Alloy based elastocaloric Cooling system (SMACool)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Germany,Italy,Slovenia,Ireland
Call: EIC Pathfinder Challenge: Clean and efficient cooling (HORIZON-EIC-2023-PATHFINDERCHALLENGES-01, 2023)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 3976608.75
EU funding (EUR): 3976608.75
Participants: 4
Project status: SIGNED

The project SMACool will develop a functional air-conditioning device for residential buildings, based on the emerging technology of elastocalorics, which uses (shape memory) alloys as solid-state refrigerants for efficient and sustainable cold (and heat) generation. Elastocalorics (also thermo-elastic or thermoelastics) is an innovative, disruptive heating and cooling technology with the potential of reaching outstanding energy efficiency and zero global warming potential, using metals as solid-state refrigerant material instead of the harmful fluids used in cooling systems today. The interdisciplinary project consortium consisting of three European Universities from Germany, Italy and Slovenia and one emerging high-tech Company from Ireland, will cover several project objectives, including the construction and validation of an application-specific elastocaloric cooling system device, the creation of a versatile validation environment for quantitative validation of future elastocaloric devices, the realization of a multi-physical numerical simulation platform for simulative assistance in elastocaloric device development, the development and characterization of elastocaloric-specific optimized materials, and the development of an efficient electric drive unit suited for the specific needs of elastocaloric system devices. The resulting SMACool system is targeting an efficiency increase by a factor of two to three compared to state-of-the-art HVAC (Heat, Ventilation, and Air-Conditioning) systems and will have high impact on potentially cutting down global energy consumption in the residential building sector and also other cold generation fields.

Keywords: elastocalorics,thermoelastic,cooling,air conditioning,shape memory alloys,hvac
3D Printed, Bioinspired, Soft-Matter Electronics based on Liquid Metal Composites: Eco-Friendly, Resilient, Recyclable, and Repairable (Liquid3D)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Portugal
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2781215.0
EU funding (EUR): 2781215.0
Participants: 2
Project status: SIGNED

Liquid3D proposes bioinspired electronics and machines that are soft, resilient, self-healing, shape-morphing, and fully recyclable. Functional sensing/acting/processing/energy cells will be 3D printed using a series of game changer Liquid Metal based composites. As a result, we will print futuristic soft electronics that sense and interact with humans or the environment. This provides an excellent design freedom to scientists for manufacturing complex “living” electronics, while guaranteeing that any possible product coming from these inventions will be Resilient, Repairable, and Recyclable. I expect that over 80% of microchips, and metals in the printed circuits, can be recovered. Liquid3D redefines the electronics, by rethinking the materials, fabrications, and design architectures. These objectives are feasible, thanks to the recent breakthroughs that I made to the field: First; discovery of the biphasic (liquid-solid) composite based on Gallium-Indium Liquid Metal (LM), that allowed the first ever method for room temperature printing of stretchable circuits; and second, a method for inclusion of microelectronics into ultra-stretchable circuits through self-soldering, self-healing, and self-encapsulating of LM-Polymer composites. With Liquid3D I will develop fundamental understanding, and mathematical modelling of biphasic systems, and develops novel room temperature printable composites with sensing/acting/energy storage properties, and methods for recycling them. I will investigate novel forms of implementing truly 3D electronics, with distributed functional cells. Liquid3D intends to fundamentally rethink, the concept of electronics, as we know today. From rigid and brittle to soft, resilient and repairable; From polluting to recyclable; from battery dependent to self-powered; from 2D to truly 3D; It proposes a radically new way of making “greener” electronics. With Liquid3D I aim to establish the world leading centre on recyclable, and green electronics.

Keywords: additive manufacturing,recyclable electronics,bioinspiration,liquid metal,stretchable electronics,robotics,graphene,printed electronics
Proximity Network Assay: driving the future of high-resolution 3D proteomics for precision medicine, drug discovery and molecular diagnostics (PNA)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Pixelgen Technologies, a deep-tech Swedish life sciences company, pioneers innovation in spatial proteomics, critical for precision medicine, cancer research, and drug discovery. Building on the success of its Molecular Pixelation (MPX) technology, Pixelgen introduces the Proximity Network Assay (PNA), enabling high-resolution, high-throughput protein mapping at the nanoscale. The PNA technology addresses current limitations in spatial proteomics, including low resolution, scalability challenges, and high costs of traditional microscopy-dependent methods. PNA technology employs a unique DNA-based approach, achieving an unprecedented 30 nm resolution and multiplexing over 160 customizable protein markers in a single assay. This will allow researchers to visualise intricate protein interactions at both cellular and subcellular levels (including cell-to-cell interactions and FFPE tissues), unlocking insights into immune responses, drug mechanisms, and disease pathology. Unlike conventional methods, PNA eliminates the need for expensive and low content optical imaging systems, providing a cost-effective and accessible solution for academic and industrial applications. PNA is currently at TRL6, with proof-of-concept data generated for key use cases. The EIC Accelerator project aims to develop PNA to TRL9 by advancing reagent development, creating optimised sample preparation protocols for FFPE tissues and cell-to-cell interaction studies, and enhancing data processing software for seamless integration with multi-omics platforms. In 24 months, Pixelgen will validate the PNA technology through pilot tests, targeting commercial launch by 2027. PNA technology will redefine spatial proteomics, enabling groundbreaking research and fostering Europe’s leadership in the biotechnology sector. The project aligns with the EU’s priorities in healthcare and digital transformation, contributing to the European Health Union’s goals of advancing diagnostics and personalised treatment.

Keywords: spatial proteomics,intracellular protein mapping,high resolution proteomics,optics free 3d protein localisation,dna based spatial mapping,protein interaction networks,sequencing enabled workflow
Energink - Boosting Batteries and Capacitors with High-Performance, Sustainable Conductive Inks (Energink)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

n-ink is developing high-performance, environmentally safe conductive polymer inks designed to boost battery range and enable heat-resistant polymer capacitors. The transition to an electrified society necessitates advancements in energy storage materials. Current solutions, like PVDF binders and carbon black additives, are inefficient, environmentally damaging, and hard to recycle. n-ink offers cost-efficient, high-performance, eco-friendly conductive inks manufactured in a scalable one-step process. Their clever molecular design ensures ultra-high conductivity (up to 3000 S/cm) and thermal stability (up to 225°C), outperforming existing materials. Our aim is to replace PEDOT:PSS in polymer capacitors, enabling advanced applications. In batteries, our inks combine the binder and conductive agent qualities, offering a fluorine-free alternative that eliminates harmful solvents. Moreover, our inks are fully compatible with existing battery production processes. Initial tests have demonstrated superior properties of our inks in polymer capacitors and batteries. We have shown production scale-up potential, reaching a capacity of 200 L/week. We have also secured a joint development agreement with reference users, highlighting the product's market potential. To reach TRL9, several development steps are planned in the EIC Accelerator project, including ink optimization, pilot tests for capacitors and batteries, demonstrating recyclability, and production scale-up. With EIC Accelerator support, n-ink aims to capture a significant share of the global conductive binder market and redefine energy storage materials. The project is set to position Europe at the forefront of advanced energy storage solutions, showcasing the EU's commitment to innovation and environmental sustainability.

Keywords: battery materials,conductive polymers,polymer capacitors,conductive binders,sustainable materials
Fail-operational safety – making autonomous vehicles a reality (TrueSbW)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-05-01
End date: 2025-04-30
Duration (months): 24.0
Total project cost (EUR): 3567578.75
EU funding (EUR): 2497305.0
Participants: 1
Project status: CLOSED

We have seen a revolution in autonomous driving technology. Today, more than 75% of newly registered vehicles have some level of driver assistance. However, despite vast strides in new AI and sensing technology, fully autonomous vehicles are yet to be realized because the actuator technology for the safety-critical steering and braking systems are not mature enough to guarantee fail-operational capability. Chassis Autonomy has developed the first fail-operational steer-by-wire system, which is suitable for fully autonomous vehicles. It is the final step toward fully driverless vehicles (i.e., no steering wheel) and will unlock the next wave of automotive driving. We have completed a series of early prototyping and validation activities and we are now seeking the support of the EIC to finalize our technology and go to market in two years to meet the roadmaps of the leading autonomous mobility developers.

Keywords: autonomous driving
Building the Global Data Access Layer for AI: Scalable, Secure, and Energy-Efficient AI Model Development (tracebloc)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Germany
Call: Human Centric Generative AI made in Europe (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 3354701.01
EU funding (EUR): 2348290.71
Participants: 1
Project status: SIGNED

tracebloc is a pioneering technology startup at the intersection of artificial intelligence (AI) and IT procurement, addressing a critical need for enterprises: the lack of in-house AI expertise to develop and fine-tune advanced AI models. As businesses across sectors increasingly adopt AI, they are often forced to rely on external AI experts to build custom models, a process hindered by lengthy onboarding, data privacy concerns, and the risks of intellectual property (IP) leakage. tracebloc provides a solution to these challenges with its secure, on-premises AI collaboration platform. Our platform enables enterprises to collaborate with AI partners—researchers, startups, consultants—while retaining full control over proprietary data. AI models are uploaded and fine-tuned directly on enterprise servers, ensuring privacy, IP protection, and regulatory compliance, including with the forthcoming EU AI Act. The platform also benchmarks AI models based on key performance indicators such as accuracy, compliance, and energy efficiency, promoting sustainable AI practices in line with global environmental goals.

Keywords: call horizon eic 2024 accelerator 02