Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Sleep genes and Circadian rhythm in dementia prevention (CLOCKED)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-10-01
End date: 2026-09-30
Duration (months): 24.0
Total project cost (EUR): 206887.68
EU funding (EUR): 206887.68
Participants: 1
Project status: SIGNED

Changes in sleep patterns are common among people with dementia, however why short (≤6hrs) or long sleep (≥9hrs) duration is less favorable for dementia, remains unknown. Given that approximately 46% & 44% of variability in sleep duration is explained by genetics, it is pertinent to consider genetic influences when understanding the mechanisms contributing to sleep-related risk for dementia. In addition to sleep, there is growing interest in the relationship between circadian rhythms, the 24-hour cycles of body & dementia. Links between Alzheimer’s’ dementia and the circadian system are suggested by common observations that an early symptom of Alzheimer’s’ dementia is fragmented sleep/wake patterns with increasing night\time activity and daytime naps. Even among individuals who are cognitively intact, altered circadian rhythms of motor activity have been linked to amyloid pathology; the hallmark of Alzheimer’s’ dementia. There is some evidence linking weakening circadian rhythm to dementia, yet it is not clear whether disruption of clock contributes to incidence dementia. In CLOCKED, I will use data from the Swedish Twin Registry with over 20 years of follow-up, the largest twin registry in the world to assess if sleep polygenic risk score influences the risk of incident dementia (overall, Alzheimer’s’, vascular) & examine whether differences in dementia risk are influenced by a genetically predicted sleep or sleep driven mainly by non-genetic factors, i.e., environmental lifestyle factors. Using accelerometry data on around 100,000 participants from the UK Biobank data, I will assess the relation of accelerometer-assessed circadian rhythmicity with incident dementia & quantify dementia risk stratified by sex, ethnicity, socioeconomic status, shift work, lifestyle factors, & metabolic status; and determine whether a risk score consisting of circadian factors (i.e., circadian syndrome) is a more accurate predictor for dementia than existing risk scores.

Keywords: dementia,sleep,polygenic risk score,circadian rhythm,accelerometer
TOPOFORM – ROBOTIC PRINTING OF LARGE-SCALE TOPOLOGY OPTIMISED COMPOSITE CONSTRUCTION FORMWORK (TopoForm)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator Challenge: New European Bauhaus and Architecture, Engineering and Construction digitalisation for decarbonisation (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2024-01-02
End date: 2026-01-01
Duration (months): 24.0
Total project cost (EUR): 3366062.5
EU funding (EUR): 2356243.75
Participants: 1
Project status: TERMINATED

Concrete is a key enabler for creating an affordable, inclusive and climate-resilient built environment. However, the use of concrete contributes a massive 8% of global GHG emissions. Topology Optimisation offers a pathway to reduce emissions now, by using up to 70% less concrete to achieve the same structural performance, while unlocking design innovation. Yet, contractors typically opt for more affordable and predictable rectangular designs that require only standard formwork (i.e. moulds) panels, resulting in a massive overuse of concrete. The challenge to adopting Topology Optimisation is 3-fold: (1) typical timber-based specialty formworks are heavy and difficult to connect to standard formwork panels, resulting in excessive and hazardous manual work to assemble/disassemble, (2) plywood tends to deform in moist conditions requiring costly onsite repair, (3) formwork may be reused 7-20 times before being incinerated or landfilled. In Europe alone, this generates +180M tons of unnecessary waste that emits +756K tons of CO2e annually. Our TopoForm system is revolutionising global concrete construction by delivering specialty formwork at a radically lower price, much faster to assemble/disassemble on-site and upcyclable/recyclable through our proprietary take-back service. TopoForm leverages our patented technology for robotic 3D-printing of lightweight composite formwork that is 52% cheaper, 5x lighter and 30% to 60% lower embodied GHG footprint. We have validated TopoForm’s superior performance and customers’ willingness to pay with our first 2 lead-customer projects in Denmark. Since founding in 2012, Odico A/S is an established pioneer in construction robotics. We now aim to scale up our TopoForm formwork technology that will accelerate the New European Bauhaus and EU Green Deal targets. By 2028, Odico will bring TopoForm specialty formwork to construction projects across Europe and beyond, reaching dedicated revenues of €82.5M and 80 total new employees.

Keywords: topology optimisation,robotic formwork production system,digital construction,sustainable construction,hybrid additive and subtractive manufacturing with thermoset composite,multi modal machining
Surfing radio Waves to detect liquId water in the solar systeM (SWIM)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Italy
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 3176790.0
EU funding (EUR): 3176790.0
Participants: 1
Project status: SIGNED

In the near future a number of space missions will aim to study the icy Galilean satellites of Jupiter to detect subglacial liquid water, using radar sounders. To properly interpret the radar data, it is necessary to understand the dielectric properties of the icy shells of these bodies, as they control radar signal penetration and anomaly (i.e., water) detection. The current knowledge of these properties for the types of water ices believed to be present is limited, which would potentially produce incorrect interpretations of the radar data, thus risking the scientific goals of these missions. Based on extensive experience in characterizing the dielectric properties of planetary analogues, which led me and my group to discover the first extraterrestrial subglacial stable body of liquid water on Mars, we intend to develop new methodologies and protocols to create a groundbreaking knowledgebase that fills this critical gap. We will apply the first of its kind methodology for conducting dielectric measurements across a wide range of frequencies (including the challenging interval used by these radar systems) and temperatures representative of the different ice-forming environments, produce groundbreaking studies on the structural and chemical behavior of different ice types using CT microtomography and molecular dynamic modelling, and will create a wide-ranging dataset of the dielectric properties of non-terrestrial ices. Such pioneering and high gain research will allow to obtain the maximum benefit from missions such as JUICE and Europa CLIPPER. By the end of the project significant and fundamental progress will be made to properly perform dielectric measurements on icy planetary analogues, in the comprehension of the physics behind the dielectric behavior of water ice and icy materials, and in radar data modelling and interpretation. Moreover, the project’s results will serve as a critical knowledge base for present and future radar sounder planetary missions.

Keywords: dielectric properties,ice penetrating radar,ice shells
SwingBots: Nonlinear Resonance for Sustainable Automation (SwingBots)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-07-01
End date: 2026-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 2
Project status: SIGNED

The SwingBots project is about constructing energy-efficient industrial robots. In our ongoing ERC-funded project, M-Runners, we developed new theoretical foundations and technological solutions for realizing repetitive robot motions mechanically, by nonlinear resonance. We now want to leverage this knowledge to build a robot where most robot motions are generated by a tuned interplay between moving masses of the robot links and elastic elements instead of purely relying on electric motors. This concept is especially beneficial for repetitive or close-to-repetitive motions as often encountered in engineering and industry. As a prominent example, we look at pick-and-place applications. By focusing on use-case identification, market research, and building a prototype with commercial viability, the SwingBots project aims to take the first steps towards commercialization, which is bolstered by the protection of several granted patents. The better the mechanical resonance matches the motions required for the applications, the less the actuators need to do - and the higher the energy efficiency. Besides efficiency, the approach promises to increase safety in human-robot interaction and more silent, robust, and cheaper robots.
RECYCLABLE MATERIALS DEVELOPMENT at ANALYTICAL RESEARCH INFRASTRUCTURES (ReMade-at-ARI)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Services and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,France,Czechia,Italy,Belgium,Greece,Spain,Netherlands,Hungary,Austria,Croatia,Sweden,Portugal,Slovenia,Finland,Switzerland,United Kingdom,Denmark,Romania,Poland
Call: Research infrastructures services enabling the development of materials for a circular economy (HORIZON-INFRA-2021-SERV-01, 2021)
Start date: 2022-09-01
End date: 2027-02-28
Duration (months): 54.0
Total project cost (EUR): 13728333.0
EU funding (EUR): 13679983.0
Participants: 51
Project status: SIGNED

A radical shift to the Circular Economy is urgently needed to cope with the challenge of finite resources decreasing at a frightening pace while the quantity of waste increases alarmingly. The European Commission`s (EC) Circular Economy Action Plan (CEAP) adopted in March 2020 has identified seven key product value chains that must rapidly become circular, given their environmental impacts and circularity potentials. This requires substantial research on materials with a very high recycling capability while exhibiting competitive functionalities. In ReMade@ARI, the most significant European analytical research infrastructures join forces to pioneer a support hub for materials research facilitating a step change to the Circular Economy. ReMade@ARI offers coordinated access to more than 50 European analytical research infrastructures, comprising the majority of the facilities that constitute the Analytical Research Infrastructures in Europe (ARIE) network. ReMade@ARI offers comprehensive services suiting any research focusing on the development of new materials for the Circular Economy in the key areas highlighted in the CEAP and plays an important role in the preparation of the common technology roadmap for circular industries. Senior scientist, facility experts and highly trained young researchers contribute scientific knowledge and extensive support to realise a user service of unprecedented quality, making each promising idea a success. Particular attention is attributed to the implementation of attractive formats to support researchers and developers from industry. The comprehensive service catalogue is complemented by an extensive training programme. Communication and dissemination activities are underpinned by a continuous impact assessment, which also enables evidence-based decision-making in the context of the proposal selection. Routes to sustainability of the platform will be explored towards the end of the project.

Keywords: research infrastructures,circular economy,sustainability challenge,materials analysis,trans national acess,ultra high resolution materials analysis,
MODULAR MANUFACTURING AND DISTRIBUTED CONTROL VIA INTEROPERABLE DIGITAL TWINS (MODAPTO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Made in Europe (co-programmed)
Countries involved: Greece,Germany,France,Austria,Lithuania,Italy
Call: Excellence in distributed control and modular manufacturing (Made in Europe Partnership) (RIA) (HORIZON-CL4-2022-TWIN-TRANSITION-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 5491685.0
EU funding (EUR): 5491685.0
Participants: 13
Project status: SIGNED

MODAPTO envisions flexible industrial systems composed of modules enhanced by distributed intelligence via interoperable Digital Twins (DTs) based on industrial standards. Moreover, it materializes enables collective intelligence within modular production schemes for effective module and production line design, reconfiguration and decision support. Motivated by the six principles of Reconfigurable Manufacturing Systems, MODAPTO aims at materializing reconfigurability through the joint use of all principles and not by considering it as an isolated vision of each one. To that end, MODAPTO focuses on two technological pillars: 1. Distributed Intelligence & Control via Interoperable Digital Twins 2. Modular Production Framework & Toolkit Within MODAPTO, each production module is augmented by a DT offering additional distributed intelligence functionalities. MODAPTO standardizes the module’s interface via AAS to enable coordination with other modules and systems. MODAPTO also proposes a framework for production design and reconfiguration supported by collective intelligence tools. MODAPTO will be implemented in 3 industrial UCs involving 4 manufacturers at 3 different levels to showcase its versatility and applicability. UC1 targets the development of production modules (robots) with novel sustainability capabilities, while UC2 production reconfiguration and optimization even for single lots. UC3 targets the timely set up of press shop lines and coordination with robots and AGVs to handle supply chain disruptions in collaboration with the producer of semi-finished product kits. MODAPTO aims at substantial KPI improvements related to efficiency, cost, quality, energy and sustainability. Moreover, MODAPTO will develop business models facilitating its transferability to other sectors and the adoption of its industrial strategies, especially by SMEs, while supporting knowledge transfer via workforce and trainers’ training activities.

Keywords: interoperable digital twin aas distributed intelligence collective intelligence reconfigurable manufacturing system sustainability new production module single lot supply chain disruptions
Feynman Graph Expansions for high Precision (FGEHP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-10-01
End date: 2030-09-30
Duration (months): 60.0
Total project cost (EUR): 1999448.0
EU funding (EUR): 1999448.0
Participants: 1
Project status: SIGNED

To an astonishing degree the laws of physics are described by the Standard Model of particle physics. Having discovered its final miTo an astonishing degree the laws of physics are described by the Standard Model of particle physics. Having discovered its final missing piece, the Higgs boson, CERN’s Large Hadron Collider has now entered its high-precision phase challenging not only the SM but also our abilities to draw sufficiently precise predictions from it. A formidable challenge will be to bring the accuracy of theoretical calculations to the percent level and, if possible, beyond. There are various bottlenecks associated to the different ingredients entering these predictions. An enormous challenge will be to improve the accuracy of partonic cross sections, which describe the scattering of the proton's constituent quarks and gluons, in perturbative quantum chromo dynamics. To reach the required precision we already now desire next-to-next-to-leading order (NNLO) predictions for 2-to-3 processes, next-to-NNLO (N3LO) predictions for 2-to-2 processes and even N4LO predictions for 2-to-1 processes. At the same time further improvements to N4LO will be required for the splitting functions which are needed for a systematic treatment of parton density functions. With the high luminosity phase of the LHC commencing in 2029 we can expect, however, that predictions of even more complicated final states will be required. It is clear that our current methods are not be up to the task. This project aspires to fill this gap through a new methodology based on very recent advances I made in Feynman graph Theory and its applications to asymptotic expansions and infrared subtraction schemes. This methodology will allow for the efficient automation of expansions around kinematic limits, leading to new pathways to obtain reliable and systematically improvable approximations for scattering amplitudes and the cross sections to which they contribute, which are currently out of reach.

Keywords: lhc phenomenology,perturbative qcd,method of regions,nlo,nnlo
Potential impact of sea level rise related salinization on lowland tropical coastal peatlands (SaLtedPeat)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1966888.0
EU funding (EUR): 1966888.0
Participants: 1
Project status: SIGNED

Sea level rise (SLR) poses risks of flooding and salinization to coastal ecosystems. At present, research on SLR impacts still heavily focuses on saline ecosystems (e.g., mangroves, saltmarshes), despite the impact of salinization being particularly dire for freshwater ecosystems. Southeast (SE) Asian coastal peatlands are freshwater wetlands playing important role in tackling the triple planetary crisis: climate change, biodiversity loss and pollution. Mainly located in low-lying coastal plains, SE Asian peatlands are highly vulnerable to the impacts of SLR. My recent research indicates that SLR-induced salinization could lead to catastrophic fires by promoting mass peat swamp forest mortality, thus increasing dead fuel availability. However, SLR impacts on SE Asian peatland ecosystem structure and functioning remain severely understudied to date. The SaLtedPeat project aims to pioneer the timely exploration of the impacts of SLR, particularly salinization, on coastal forested peatlands of SE Asia. Within this project, my team and I will explore the historical relation between SLR and severe fire occurrences in SE Asian coastal peatlands using long-term ecological studies as well as analyse the contemporary land-sea gradients in peatlands through field observations. We will mimic the impact of SLR-related salinization on peatland vegetation and peat physicochemical properties by performing a salt-addition experiment, and model changes in peatland properties and C stocks following SLR and projected precipitation changes. The SaLtedPeat project will unravel the potential (hidden) impacts of SLR on SE Asian peatlands, provide the first assessments of salinity (in)tolerance of peat swamp forests, advance knowledge on the ecosystems’ spatiotemporal variability, and estimate potential C loss following SLR. The project outputs will also assist in developing solutions to overcome the triple planetary crisis, i.e., (i) keep or grow C stocks, (ii) maintain habitat for biodiversity and (iii) avoid fire-induced air pollution.

Keywords: forested freshwater coastal wetlands,ghost forest,coastal habitat loss,fire risks,carbon stocks,triple planetary crisis
CHIP-SCALE ATOMIC OPTICAL CLOCK-HOP ON (CSOC-HopOn)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Research and Innovation actions
Countries involved: Belgium,Poland
Call: Hop on Facility (HORIZON-WIDERA-2023-ACCESS-06, 2023)
Duration (months): 18.0
Total project cost (EUR): 535137.5
EU funding (EUR): 535137.5
Participants: 2
Project status: SIGNED

The primary objective of the original project is to develop a Chip-Scale Optical Atomic Clock (CSOC) using 1310nm and 1556nm light sources combined with 85Rb atomic transitions. With the addition of a new Widening Partner (WP) to the CSOC consortium, the project's scope gains a new dimension. The consortium now gains access to Gallium Nitride (GaN) based visible light emitters adding additional wavelength range from 390nm to 520nm, with a specific focus on integrating a 461nm laser diode into the CSOC photonic circuits. The introduction of the 461nm laser is significant as it aligns with the requirements of the 87Sr optical atomic clock, potentially enabling cross-utilization of technologies between different atomic clock platforms. Exploring the blue spectrum with a 461nm wavelength holds great promise for future optical atomic clocks, enhancing precision and advancing chip-scale optical components and photonics. Successful integration of GaN-based emitters and SiN waveguides into the CSOC project could also spark interest in various other applications, including telecommunications, optical sensing, and quantum technologies. The methodology involves two routes: hybrid-integration of separate GaN and SiN chips and hetero-integration of GaN chip onto SiN structure using transfer printing. By pursuing both integration pathways for GaN emitters and SiN chips in parallel, the project aims to maximize success within a tight timeframe while comprehensively assessing each approach's strengths and weaknesses. The impact of adding the WP includes enhanced expertise in GaN research, expanded capabilities for GaN-based device development, and access to valuable market insights. This collaboration also benefits students and researchers, strengthening the workforce in semiconductor and optoelectronic fields.

Keywords: photonic chip,iii nitride integration