Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
MOLECULAR EVOLUTION ACROSS THE SOLANACEAE: MICRO- AND MACROEVOLUTIONARY PROCESSES LINKED TO DOMESTICATION (SOLUTION)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2012-11-01
End date: 2016-10-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The project is related to evolutionary biology and aims to investigate the variation in evolutionary patterns of polymorphism induced by domestication, at the genome scale, using NGS, in 3 horticultural crop species, of the Solanaceae family (tomato, pepper and eggplant) both at (1) the intra specific level and (2) the interspecific level. Surprisingly, few studies have investigated such patterns in nuclear genes in plants. Within Solanaceae these species are of both economical and scientific interest and have undergone different domestication history. We are targeting the transcriptome of domestic and wild accessions in each species while using (1) methodological approaches in evolutionary biology to reveal genes under positive or stabilizing selection to compare evolutionary history and (2) use the latest statistical developments to investigate domestication scenarios. To explore the potential contribution of evolutionary parameters to the total variance in evolutionary rate among genes, factors such as GC content will be analyzed. The project will be one of the first projects investigating molecular signatures of evolutionary changes at the genome scale induced by domestication in three major horticultural crops. It will allow the release of a large amount of data produced using NGS and associated statistics. This CIG will benefit to my career by offering the opportunity to accumulate valuable research experience in the emerging field of large-scale comparative evolutionary genomics. The host organisation, UR GAFL INRA benefits from a rare combination of scientific experience, research facilities, leadership in the field of genomics in plants, and large collections of varieties of these crops. The project will offer me (1) a unique combination of conditions to pursue a first plan scientific research career and (2) an international visibility in evolutionary biology to create a network of scientific partners leading to news collaborations.

Keywords: natural sciences,evolutionary biology
Competition between bottom-up and top-down mechanisms of auditory attention: neurophysiological and physiopathological mechanisms of distractibility. (DISTRACTIBILITY)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2012-03-01
End date: 2016-02-29
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Attention is the brain function by which we, voluntarily or not, improve the processing of specific information in our environment while other information is disregarded. In principle, the entry of information to the limited-capacity system is controlled by two types of processes: top-down (TD) and bottom-up (BU) processes. TD attention enables the good performance of an on-going task by selecting the relevant information. One’s attention can also be involuntarily captured by an unexpected salient stimulus and thus diverted from the previously on-going task. This BU form of attention is necessary to be aware of potentially important events that are nonetheless irrelevant to the on-going task (e.g. fire alarm), and is commonly referred as distractibility. A good balance between BU and TD mechanisms is thus crucial to be task-efficient while being aware of our surrounding environment. This precarious balance is often affected in neurological and psychiatric disorders (e.g. attention-deficit hyperactivity or bipolar disorder, autism). Lack of distractibility points to the dominance of TD attention, whereas enhanced distractibility could be due to either reduced efficiency of TD mechanisms, or enhanced triggering of BU attentional capture. Despite the obvious importance of distractibility in assessing the patients’ neurological status, no generally accepted index of it has emerged in clinical practice. Currently available tests of attention focus on top-down mechanisms of attention and fail to provide an indication of any alteration in BU attentional capture. Therefore, this project aims at proposing a new paradigm to assess both BU and TD attention mechanisms, at the same time. At a basic level, this paradigm will provide crucial information on how these mechanisms compete in the healthy brain. On the clinical side, the better understanding of the physiopathological mechanisms of BU and TD attention will permit the optimization of a new distractibility test.

Keywords: neurophysiology,neuropsychology,electrophysiology,preparatory attention,anticipation,distractibility,attentional capture,prefrontal cortex,bipolar disease
Mitochondrial deficiency and cardiomyopathy. Role of Reactive Oxygen Species (ROLROS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2012-04-02
End date: 2016-04-01
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Mitochondrial diseases are now considered to be among the most common forms of genetic disorders, with a minimum prevalence of 1 in 5000 individuals. They can be caused by mutations in either the nuclear or the mitochondrial DNA (mtDNA). One of the most well characterized clinical presentations is neuromuscular dysfunction, followed by cardiomyopathy, generally in the form of hypertrophic cardiomyopathy. Nowadays there are several clinical treatments approved for mitochondrial diseases. However true treatment is, with some exception, unavailable due to the complexity of the disease and the side effects observed. Several mutations involving mt-tRNA genes (mainly Leu1, Lys and Ile), mt-encoded protein and nuclear encoded protein genes have been associated with cardiomyopathy. Some of these mutations have been deeply studied in a cybrid cell culture model at the biochemistry level. However, very little is known about the signalling pathways that could lead to the development of cardiomyopathy. Mitochondrial physiology and biogenesis are deeply involved in the initiation and progression of the disease, through reactive oxygen species (ROS) production, energy deficiency and decrease in mitochondrial respirasome formation, as initial steps in the formation of the plaques. Recently, it as been demonstrated the role of some mitochondrial biogenesis-related genes, such as PGC1a, in mitochondrial fusion, pointing to the importance of the balance between mitochondrial fusion-fission in the progression of the disease. Interestingly, some of the mutations described in cardiomyopathy are very ROSgenic, strongly pointing to ROS and mitochondrial deficiency as an initial step in the onset of the cardiomyopathy. The aim of this project is to better understand the involvement of mitochondria in cardiomyopathies using different models of mitochondrial diseases that curse with increase ROS production.

Keywords: cardiomyopathy,mitochondria,cardiovascular disease,reactive oxygen species,signalling
3D Circuit Quantum Electrodynamincs with Flux Qubits (CQ3D)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2012-02-01
End date: 2016-01-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

cQ3D proposes a 48-month program to improve the quantum coherence of superconducting flux qubits using cutting-edge developments in circuit quantum electrodynamics (QED). Beyond the immediate benefit to quantum computing with superconducting circuits, this effort will enable fundamental physics, such as the investigation of non-equilibrium quasiparticles in superconductors. Finally, it will pave the way for hybrid quantum computing with superconducting flux qubits coupled to electronic spins. cQ3D will first focus on achieving strong coupling of flux qubits to three-dimensional (3D) superconducting resonators. The evolution from 2D to 3D circuit QED reduces the contribution of lossy metal and dielectric surfaces and interfaces to qubit energy decay by storing this energy primarily in vacuum. By providing a means to control, couple and measure flux qubits in a near-perfect electromagnetic environment with minimal additional circuitry, we aim to surpass and elucidate current limits to coherence in flux qubits. In particular, this pursuit may uncover a contribution from non-thermal distributions of quasiparticles, as predicted by recent theory. The developed architecture will finally be used to couple small ensembles of electronic spins to flux qubits and/or to resonators using flux qubits as a quantum interconnect. A CIG grant will facilitate the local and international integration of my new group at TU Delft by creating opportunities for collaboration and discussion with several faculty in the Kavli Institute of Nanoscience, and facilitating research complementing that of my international collaborators. Simultaneously, this grant will enable key infrastructure developments in fabrication and simulation that will impact my group beyond the tenure-track race.

Keywords: physical sciences,superconducting quantum circuits,quantum information processing,quantum coherence,hybrid quantum systems
Understanding Iran‘s Resumption of its Nuclear Program: The Role of Govermental Politics (NUCBURPOLITICS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Türkiye
Call:  (FP7-PEOPLE-2011-CIG, 2011)
Start date: 2013-01-01
End date: 2015-12-31
Duration (months): 36.0
Total project cost (EUR): 75000.0
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Iran’s nuclear program continues to concern scholars and policy-makers alike. In particular, the relative changes over time in the behavior of the Iranian regime over its nuclear program are further puzzling. Whereas during some periods Iran seems cooperative toward the international community, at other times Iran displays a defiant status. This change and continuity deserves specific attention from an international relations perspective. Theoretical perspectives on foreign policy argue that one must either look at either strategic/security concerns or cultural/normative issues. However, these approaches come short of explaining the internal governmental changes in the regime that may explain the shifts in foreign policy. This is especially the case with respect to Iran; although strategic and cultural variables are fairly constant, the divergence in foreign policy must be accounted for by a perspective that looks at the internal dynamics of the regime. The hypothesis is that a governmental politics perspective can shed light on the changes in Iran’s nuclear and foreign policy by analyzing the shifts in the relative distributions of power within the regime. By analyzing the regime’s key cooperative periods such as the 2004 Paris agreement with the European Union, and Tehran’s defiant periods such as during 2006, the project seeks to identify the key internal causal mechanisms that shape the nuclear and foreign policy of Iran. Beyond the academic value of explaining Iranian nuclear policy, the project will shed light on an extremely important issue for the European Union—namely EU’s ability to produce desirable outcomes in its neighborhood. In other words, the project will analyze the extent to which European sanctions and incentives have an effect on a target country. By focusing on the governmental politics of Iran, one can understand how European incentives and sanctions are received and played out in a domestic political setting. Accordingly, the project offers European policy-makers a better understanding of the implications of their policies in their external relations.

Keywords: international politics,international relations,international studies
Reduction in Maintenance Costs of Wind Turbine Renewable Electricity Generation through Online Condition Monitoring (MONITUR)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: United Kingdom,Finland,United Kingdom,Türkiye,United Kingdom,Poland
Call:  (FP7-SME-2012, 2012)
Start date: 2013-01-01
End date: 2014-12-31
Duration (months): 24.0
Total project cost (EUR): 1377763.39
EU funding (EUR): 1062000.0
Participants: 7
Project status: CLOSED

To achieve the EC binding targets of 20% electricity generation from renewables by 2020 will require between 600 and 833 TWh to be produced by wind power which will require between 119,000 to 165,000 new turbines. According to the European Wind Energy Technology Platform publication “O&M strategies are based on periodic inspection; fault statistics from existing stock is either unavailable or insufficient; maintenance needs to be minimised through preventative strategies and tools like conditional monitoring; performance of offshore farms is severely impacted by poor reliability leading to major production losses.” Turbines are not achieving a design life of 20 years with failure rates of >1/turbine/year, remote tall structures mean that maintenance and inspection is costly and difficult. Replacing a €3000 bearing can turn into a major €165,000 cost involving cranes, crews etc. For on-shore turbines operation and maintenance costs 10-15% of income over 20 years, rising for offshore to 20-25%. Intermittency of wind power also requires standby generation by open cycle gas turbines (aero-derivative units) in order to attain rapid start-up and load following capability. These units have markedly lower MTBF compared with steam and gas turbines. This consortium wish to develop a means to perform prognosis, diagnosis and root cause analysis of rotating machines via new time-frequency analysis techniques (based on higher order spectra) to the machine vibration signature during transient operation. This differs from classic techniques which have been applied to stationary signals. Thus we overcome the problems that components cannot be excited during steady state operation and precise resonance frequencies are not known. Our project will enable the prediction of component life based on measurements, not calculation even with the problematic nature of wind loads and through preventative maintenance dramatically reduce the maintenance costs within the industries mentioned.

Keywords: non-destructive testing,time-frequency analysis,machine vibration signature
One component waterborne barrier coatings (BARRIER PLUS)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SME associations
Action type: Research for the benefit of specific groups
Countries involved: France,United Kingdom,Norway,Belgium,Greece,Portugal,Spain
Call:  (FP7-SME-2012, 2012)
Start date: 2014-01-01
End date: 2017-06-30
Duration (months): 42.0
Total project cost (EUR): 2541683.46
EU funding (EUR): 1914207.37
Participants: 11
Project status: CLOSED

Steel is the most used metal in construction and the costs of protecting Europe’s structural steel installations and assets from corrosion is thought to be 3% of GDP (or about €375BN). However, there are two factors that will increasingly affect future protective coatings developments: VOC emissions and health/safety issues. Firstly there is a strong mandate to apply VOC emissions legislation to protective coatings (and in particular extend the Paint Products Directive to include them). Secondly REACH, together with increasing effects of chemicals on humans supported through medical literature, may prevent the use of some coating materials. Our vision for BARRIER-PLUS is to develop one component waterborne barrier coatings that are competitive in performance to two component coatings. One component waterborne coatings have a number of advantages over two component coatings and solventborne systems: low VOC emissions; low fire risk; lower insurance issues; no exposure to isocyanates, epoxy resins or amines; no waste or poor film performance arising from pot life problems. Our approach is to build upon recent research in the organic/inorganic nanocomposites field to create enhanced film barrier properties. Although this project is focused on the protection of steel, the technology developed will have application in the protection of other substrates, eg concrete, brickwork and stonework.

Keywords: anti-corrosion,barrier,waterborne,coating,steel
Development of a novel Industrial Fish Drying and Maturing Process to secure Seafood Safety, Traceability, and Quality (SAFETRACKFOOD)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Estonia,Germany,Norway,United Kingdom,Netherlands,Italy
Call:  (FP7-SME-2012, 2012)
Start date: 2012-12-01
End date: 2015-04-30
Duration (months): 29.0
Total project cost (EUR): 1473444.0
EU funding (EUR): 1134000.0
Participants: 7
Project status: CLOSED

The European Union (EU-27) is a net importer of seafood with an overall negative trading balance of 3.9 million tonnes worth €13.7 billion, while importing 6.2 million tonnes worth €17.3 billion and exporting 2.3 million tonnes worth €3.5 billion. The total world trade of seafood has reached in 2004 a record export value of almost €54 billion, representing a 23% growth relative to 2000. Analysis of trends in the seafood industry shows new business opportunities in new innovative value added products in terms of convenience and health. Ready-to cook or ready-to-eat products, coated products and other value-added items constitue a fast-growing industry. The European stockfish industry - producing matured and dried gutted whole fish (round fish) from lean fish, mainly cod, but also ling, tusk, haddock and saithe - is facing several problems to follow the new market trend and to be competitive. Today, the stockfish production is still performed outdoors, where the fish is hanging unprotected on wooden rack using the sun and wind to dry. The stockfish product quality varies greatly with varying weather conditions. Today, up to 40% of the stockfish product is lost due to poor process quality. Our idea is to develop an innovative indoor process line for the maturing and drying of stockfish equipped with an Automated Bioprocess Control System to assure seafood safety and quality and will be of use for quality drying of gutted and de-headed round fish in general. We propose to use innovative Microsystem Technology (MST) and developing a miniaturised low-cost sensing platform. An automated bioprocess control system will be developed to monitor and control the maturing and drying processes. This allows reducing the production time by a factor of 4, from 4 months down to 30 days by accelerating the maturing and drying process through optimising production parameters.

Keywords: fish sensoric,odour,sensing of volatile compounds,microsystem technology (mst)
Ash Ingestion Detection Apparatus for aircraft (AIDA)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Cyprus,United Kingdom,United Kingdom,Türkiye,United Kingdom,Greece,Romania
Call:  (FP7-SME-2012, 2012)
Start date: 2013-01-01
End date: 2014-12-31
Duration (months): 24.0
Total project cost (EUR): 1208911.8
EU funding (EUR): 930968.0
Participants: 7
Project status: CLOSED

Aircraft frequently encounter volcanic ash when airborne. In the aftermath of these encounters, virtually the entire fuselage of an aircraft can be contaminated with ash, necessitating a thorough cleaning of the cockpit, instrument panel, circuit breaker panels, passenger and baggage compartments. The electrical and avionics units can be so heavily contaminated that complete replacement is necessary, mainly due to the possibility that all the units could have suffered from overheating. The ash also contaminates the cargo-hold fire-warning system and can generate nuisance fire warnings which are due to the volcanic ash in the air rather than smoke from a fire. The present proposal aims to provide an advanced airborne volcanic ash detection apparatus which will make use of special machine vision interrogation of volcanic ash (tephra) and novel image analysis software. The integrated retrofittable system will examine air in the aircraft’s ventilation ducts. By interrogating foreign bodies in the fresh air entering the cabin and identifying the type, size and number of particles per unit time and inferring the presence of low level ash particles in the possible presence of other solids in the air e.g. sand etc an early warning may be conveyed to the crew whence appropriate action may be taken to reduce the exposure of the aircraft, thus making possible enormous savings on maintenance costs.

Keywords: machine vision,image analysis