Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Landscapes of Mediterranean Celts: palaeoecological and geoarchaeological perspectives of Iron Age transmediterranean contact and interaction (CELTMED). (CELTMED)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-10-01
End date: 2026-09-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 2
Project status: TERMINATED

In Western Europe, the onset of the Iron Age implied a series of critical cultural and technological changes that were to a large degree connected with the development of contact and exchange networks with the Mediterranean World. New cultural influences, involving different traditions of land and resources management, spread especially from Greek colonies into the sphere of the rising Celtic civilization, where they merged with autochthonous dynamics and promoted changes in social structures, economic and productive systems and land use. However, very few studies have openly addressed the environmental and landscape consequences of the Greek colonization in the Celtic world, and thus its impact and role in the shaping of Western European cultural landscapes remains largely overlooked. To fill in this gap, CELTMED will employ an integrated multidisciplinary approach merging palaeoecology and geoarchaeology in three selected sites subject to different degrees of Greek influence: Abdera, an Aegean colony representing the genuine landscapes of the Greek World; Corent, a Gallic oppidum in central France exemplifying genuine Celtic landscapes; and Lattara, an hybrid Celtic site with a harbour under important Greek influence, located in the contact area of both civilizations in the coastal wetlands of SE France. CELTMED will use high-resolution, multi-proxy palaeoecological and geoarchaeological analyses of sedimentary archives, combined with archaeological data, to reconstruct and compare socio-environmental dynamics and landscape change across this transmediterranean geographic and cultural transect from coastal Greek to Continental Celtic worlds. This will allow to explore how the interplay between both cultures from the early Iron Age changed the way Celtic societies interacted with their environments and contributed to the shaping of cultural landscapes in the Celtic area, providing a new and more comprehensive knowledge of the history of Western European landscapes.

Keywords: palaeoenvironment,geoarchaeology,landscape evolution,socio environmental interaction,human impacts,fire history,non pollen palynomorphs,malacology,mediterranean,greeks,celts,iron age
Developmental Crosstalks between Microglia, Blood-Brain Barrier and Maternal Microbiota (MicroBBB)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 1499964.0
EU funding (EUR): 1499964.0
Participants: 1
Project status: SIGNED

Brain functioning can be influenced by body ecosystem signals conveyed through the vasculature and regulated by the blood-brain barrier (BBB), a selective and modulable barrier that controls which substances and cells enter the brain. Structural or functional BBB deficits are found in many brain diseases, from neurodevelopment to neurodegeneration, thus understanding how the BBB develops holds critical significance for both biologists and clinicians. Yet, we still lack fundamental knowledge on how interactions between different cellular populations in coordination with environmental signals contribute to BBB construction during early development. To tackle this issue, we will focus on the core components of the BBB -pericytes and endothelial cells- and microglia, the brain resident macrophages. Microglia play key roles in circuit assembly and we have shown that prenatal microglia, which are in close apposition to the vasculature, respond in a sex-specific manner to signals derived from the maternal microbiota. Here, we will study the developmental crosstalk between microglia and BBB in both male and female embryos by investigating (i) how pericytes influence prenatal microglia; (ii) the spatiotemporal heterogeneity of BBB closure and implication of microglia; and (iii) the impact of maternal microbiota on BBB formation and crosstalk with microglia. Our approach leverages multidisciplinary and state-of-the-art techniques in newly developed murine models of microglia depletion and in utero antibiotic treatment, including two-photon live imaging, single-cell and spatial transcriptomics, in vitro BBB model and comparison to human embryos. Ultimately, we will establish an integrated framework of BBB formation and BBB-microglia interplay, shedding light on how signals from maternal microbiota shape brain development. Our findings will provide key insights into normal and pathological brain wiring, paving the way for the identification of potential therapeutic targets.

Keywords: microglia,blood brain barrier,blood vessels,pericytes,microbiota,embryogenesis
When security spills over: Negotiating LGBTI+ security through the regulation of disinformation (SECURE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom,Belgium
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 2
Project status: SIGNED

In recent years, promoting LGBTI+ rights and countering disinformation have become pressing priorities for several Western governments. Due to the potential for disinformation to fuel discrimination, hostility, and violence against vulnerable groups, these two objectives are increasingly intersecting in local, regional, and international political processes. To regulate disinformation, particularly on social media, state actors worldwide have primarily resorted to a security rhetoric, presenting the issue as an existential threat to security, human rights, democracy, and the rule of law. While many scholars have explored how disinformation campaigns are impacting the advancement of LGBTI+ rights, we still know very little about how this specific agenda has been incorporated to justify the securitisation of disinformation. Even less is known about the role LGBTI+ civil society has played in this process—a sector that is highly affected by the spread of false narratives but is also increasingly reliant on the services provided by these platforms to connect with the community, launch awareness campaigns, and raise funds. How they position themselves vis à vis the state, private sector and other actors in the regulation process? And how is the engagement in this field shaping the claims of LGBTI+ organisations for “protection”? SECURE will analyse how the security discourses and practices from the anti-disinformation field are spilling over into LGBTI+ rights. Through a comparative study between Poland and Brazil, two countries that have recently experienced intense polarisation around LGBTI+ rights related to the spread of disinformation, the project will develop a transferable theoretical framework to analyse multilevel security spillover processes and theorise about the current shift from “equality” to “protection” in “LGBTI+ governance”—the ways in which LGBTI+ people and ideas are incorporated into state, state-like, and state-affiliated power.

Keywords: disinformation securitisation lgbti rights lgbti civil society lgbti governance internet governance international relations political sociology
Autonomous Multi-Format In-Situ Observation Platform for Atmospheric Carbon Dioxide and Methane Monitoring in Permafrost & Wetlands (MISO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Innovation actions
Countries involved: Norway,Sweden,Denmark,Germany,France,Italy,United Kingdom
Call: New technologies for acquiring in-situ observation datasets to address climate change effects (HORIZON-CL6-2022-GOVERNANCE-01, 2022)
Start date: 2023-01-01
End date: 2026-06-30
Duration (months): 42.0
Total project cost (EUR): 3062162.5
EU funding (EUR): 2644357.0
Participants: 8
Project status: SIGNED

Climate warming is driven by increased concentrations of greenhouse gasses (GHGs) e.g., CO2 and CH4, in the atmosphere. Existing observatories are able to capture GHG information for large-scale global assessments, but short-term natural variability and climate-driven changes in atmospheric CO2 and CH4 remain less known. There is also currently a lack of sufficiently precise, autonomous, and cost-efficient GHG sensors for GHG monitoring at sufficient spatial scale, and in hard-to-reach areas. MISO will develop and demonstrate an autonomous in-situ observation platform for use in hard to reach areas (Arctic, wetlands), for detecting and quantifying carbon dioxide and methane gasses, using a combination of stationary and mobile (drone) solutions and requiring minimum on-site intervention when deployed. To achieve this objective, MISO will improve detection limit and accuracy of a NDIR GHG sensor, which will then be used in three observing platforms (a static tower, a static chamber and a UAV-mounted sensor) operated with the help of a central base unit. All elements will be designed for operation in harsh environments and with minimum human intervention. The static observatories will be powered by a unique geothermal device. Communication between the three observatories and a data cloud will use a combination of P2P, G4/G5/LTE, LORAWAN and wifi technologies. The specifications of the platform will be co-developed with stakeholders from academia, monitoring and measurement systems, industry and policy. A clear DCE strategy and focus on short-term impact management and medium and long-term commercialization will target several user groups including industries and representatives of main monitoring systems and infrastructures (e.g., ICOS). This will support innovative governance models and science-based policy design, implementation and monitoring. Sustainability performance and competitiveness in the domains covered by HE Cluster 6 will be enhanced.

Keywords: in situ observation,new cost effective ghg monitoring solutions,ndir sensor,autonomous system,uav based measurement,automated gas chamber,arctic,wetlands,ch4 co2 monitoring
The Impact of Cultural Stereotypes in European Multi-Level Policy Enforcement (EUROTYPES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Cultural stereotypes are often present in the political and media discourse on European Union (EU) governance: e.g., the lazy Greeks, the tax-dodging Italians, the stingy Dutch, and so forth. Especially when stereotypes are negative, they create conflict between national governments, fuel Euroscepticism among voters, and can lead to the discrimination of citizens or Member States. Yet while stereotypes have been studied in political rhetoric and media coverage, we know little about their impact on the behaviour of national and EU officials. To address this gap, EUROTYPES sets out to investigate how cultural stereotypes impact cooperation and effectiveness in contemporary EU governance. The project is the first of its kind because it studies stereotypes among civil servants as opposed to political elites in the EU, who often use stereotypes strategically for electoral gains. The focus is on multi-level policy enforcement, a new phenomenon in European integration which captures the participation of national and EU civil servants in joint ‘on-the-ground’ operations in border control, law enforcement cooperation, financial supervision, etc. Since they are not socialized in Brussels or running for office, such officials are much more likely to (genuinely) display cultural stereotypes. EUROTYPES pushes the frontiers of knowledge in several directions. First, it applies an original version of qualitative content analysis to identify stereotypes relevant for multi-level policy enforcement. Second, it uses recent developments in experimental research to capture the role of stereotypes among civil servants. Theoretically, the project constructs an innovative account of stereotypes as habits and positions them vis-à-vis other explanations of political behaviour (interests, norms, ideas). The goal is to show whether and how stereotypes hinder EU cooperation and, in the long run, establish a comprehensive research agenda on cultural stereotypes in transnational bureaucracies.

Keywords: cultural stereotypes european union multi level governance eu policy implementation bureaucratic behaviour eu agencies migration police cooperation banking supervision
Biological nitrification inhibition (BNI) of the root exudates under drought stress in wheat and maize (ExuRoots)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-06-01
End date: 2026-05-31
Duration (months): 24.0
Total project cost (EUR): 183600.96
EU funding (EUR): 183600.96
Participants: 1
Project status: SIGNED

Globally, the use of nitrogen (N) fertilizer for agricultural purposes is tremendous, with an estimated total of 120 million t/year. Due to high nitrification activity in the soil, much of the N applied to farmland (about 70%) is not absorbed by the crops and gets washed out, resulting in water pollution and the emission of nitrous oxide (N2O), a powerful greenhouse gas (298 times CO2 global warming effect). Suppressing the nitrification rate of agricultural soil could be a sustainable solution. Plant roots can exudate natural compounds that prevent nitrification, a process known as biological nitrification inhibition (BNI). Wheat and maize are staple cereals that require excess fertilizers, and their efficiency has not increased to meet future food demand since 1980. The main aim of this study is to screen root exudates secondary metabolites of diverse wheat and maize genotypes for their BNI compounds and also evaluate the BNI potential under drought stress. Even though wheat and maize are major cereals covering the largest area among food crops, the study of its root exudates and the potential presence of BNI compounds and related BNI capacity have scarcely been studied. Consequently, the discovery possibility of new BNI compounds remains minimally explored in these crops, and root exudate plasticity in response to environmental changes is still extremely limited. The evaluation and selection of crop varieties lowers the nitrogen fertilizer dependency and is suitability for sustainable agriculture translates into specific key activities; 1) biochemical characterization of agronomic and environmental traits of the germplasm collection, 2) measurement of secondary metabolites in root exudates of germplasm lines in glasshouse under drought stress conditions to explore the full diversity of natural metabolic variation and BNI activity, and 3) potential isolation of new BNI compounds, and understand how plant traits and phylogeny are associated to this capacity.

Keywords: plant metabolomics root exudates bni abiotic stress crop improvement
Broadening the coverage of metabolites in faeces through advanced analytical strategies (FaecMet)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-02-01
End date: 2024-02-29
Duration (months): 13.0
Total project cost (EUR): 82656.48
EU funding (EUR): 82656.48
Participants: 1
Project status: CLOSED

The analysis of human faecal metabolites can provide an insight into metabolic interactions between gut microbiota and the host organism; furthermore, it can be instrumental to not only treat, but also intercept or even prevent diseases. The present project proposes the development, validation and application of two complementary chromatographic platforms (GC/MS and LC-IM-QTOF-MS) in combination with solid phase microextraction (SPME) as a greener, high throughput sample preparation method for faecal metabolites study, more specifically, volatile organic compounds (VOCs) and bile acids (BAs). As a proof-of-concept, faeces from patients with anorexia nervosa (AN) will be analyzed and compared to that obtained from health individuals (controls) aiming to identify possible biomarkers and/or associations between metabolites. Furthermore, patients with AN display nutritional, metabolic, hypothalamic, and endocrine abnormalities, which can lead to them presenting modified microbiota. Interestingly, eventhough AN patients often avoid cholesterol-rich food, hypercholesterolemia is commonly diagnosed in AN patients. In this context, the current project also aims to investigate possible correlations between short chain fatty acids and bile acids levels, BMI, and blood lipidic profile (cholesterol) for patients with anorexia nervosa (AN) and healthy individuals (controls) individuals that could shed light into the gut health, development of hypercholesterolemia, and establish the microbiota role in the evolution of the disease. Moreover, this project aims to develop simple to execute, greener, automated sample preparation for faecal samples that could be easily implemented in clinical settings.

Keywords: solid phase microextraction faeces metabolites biomarkers volatile organic compounds vocs short chain fatty acids bile acids sample treatment biocompatible anorexia microbiota
Nanoscale Phovoltaics Laboratory On a Tip (NanoPLOT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 2976479.0
EU funding (EUR): 2976479.0
Participants: 1
Project status: SIGNED

Next generation solar cells based on metal halide perovskite (MHP) materials promise cheaper and more energy-efficient photovoltaic and optoelectronic devices compared to current silicon-based technologies. To further advance MHP technology, however, will require fundamental understanding of processes leading to energy losses, unstable operation conditions and premature aging. The macroscopic properties of optoelectronic MHP devices are the result of the complicated interplay between structure and function. Thus, the key to understanding MHP materials is to look at the many nano- and microscale structures, from sub-granular twin domains, over grain boundaries and interfaces to lateral variations in crystal orientations and facets. The aim of this project is to reveal fundamental nanoscale processes and explore the connections to the macroscopic properties of MHP materials. Therefore, we will develop NanoPLOT, an innovative microscopy platform combining the lateral resolution of state-of-the-art atomic force microscopy (AFM) with the high temporal and spectral resolution of ultrafast optical spectroscopy. NanoPLOT will not only allow spatially correlated mapping of, e.g., the local electron dynamics or photoemission spectra together with the nanoscale surface photovoltage, photocurrent or ion dynamics. The most exciting possibilities will come from entirely new imaging methods based on combinations of the available scanning probe and optical methods. Using the 2-10 nm wide AFM tip, we will address and excite individual nanostructures, enabling the characterization of optoelectronic properties at unprecedented spatial and temporal resolution. The new experimental capabilities will enable addressing some key challenges of MHP research, such as phase segregation and degradation effects, interface heterogeneity and strain effects, enabling a deeper understanding of loss mechanisms and intrinsic instabilities that will enable more efficient and stable MHP solar cells.

Keywords: metal halide perovskites,perovskite solar cells,scanning probe microscopy,kelvin probe force microscopy,optical spectroscopy,time resolved photoluminescence