Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Avantis STructural Rod Adjustment SYstem (ASTRASY)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: France,France,France
Call: Adjustable high loaded rod (H2020-CS2-CFP06-2017-01, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 534301.25
EU funding (EUR): 399490.25
Participants: 3
Project status: CLOSED

The aim of the project is to design, define, realize and test one prototype of adjustable length structural rods that can withstand high loads encountered in the aeronautical field. Two overall concepts will be studied and one of them will be retained for the prototype. First solution consist to reinforce existing adjustable rods locally by welding titanium threaded inserts in order to support high loads and avoid fatigue problems. The second solution consists to invent a welded assembly method and the associated tool in order to complete the manufacture of rods on the aircraft during integration phase. During this project, the AVANTIS Company, specialized in innovative aeronautical design and ARMINES laboratory will take the required measures to evolve from first ideas to the final demonstrator and to upgrade the technology readiness level (TRL) from 2 to 4.

Keywords: adjustable length rod,high loads,magnetic pulse welding,friction stir welding,threaded inserts,manufacturing cost optimization,on aircraft completion tool
ClearPlasma is an innovative medical device that enhances coagulation properties for improved treatment of excessive bleeding. (ClearPlasma)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-11-01
End date: 2020-02-29
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Each year, almost 2 million people die from haemorrhaging, or blood loss. Massive blood loss can occur upon: Trauma, Surgery, Childbirth, Disseminated Intravascular Coagulation (DIC), Gastrointestinal Bleeding, etc. In all of these cases, there is an urgent need for efficient plasma transfusion to halt the bleeding. However, recent studies have shown that regular plasma fails to stop massive bleeding, while other treatments show low efficacy and increased mortality risk. ClearPlasma is an innovative filtration system that modifies human plasma to improve the treatment of massive bleeding and bleeding disorders. By extracting plasminogen, an important protein responsible for dissolving blood clots, ClearPlasma enhances coagulation and favours haemostasis, thus reducing bleeding of 55%. This translates into the opportunity to reduce up to 45% the units of plasma needed during transfusion, hence reducing treatment costs. ClearPlasma is a disposable filter that can be incorporated in current Apheresis systems thus not affecting common clinical practices. ClearPlasma addresses the Global Blood Transfusion Diagnostics Market, which was valued at approximately € 3.2bn in 2017, and is expected to reach around € 4.7bn by 2024, growing at a CAGR of 6.2% between 2018 and 2024. The proposed work in Phase 1 of the SME instrument fits into our overall plan to reach the market by contributing the financial resources needed to plan a fast sound wider deployment of ClearPlasma and its market uptake.

Keywords: blood filter,plasminogen,blood transfusion,hemorrhage,surgery
Unmanned Aerial Vehicle Vertical Applications' Trials Leveraging Advanced 5G Facilities (5G!Drones)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Austria,Estonia,Estonia,Finland,Greece,Poland,Slovakia,Greece,Switzerland,Finland,Greece,Finland,France,France,France,France,United Kingdom,United Kingdom
Call: Advanced 5G validation trials across multiple vertical industries (H2020-ICT-2018-3, 2018)
Start date: 2019-06-01
End date: 2022-11-30
Duration (months): 42.0
Total project cost (EUR): 12870578.75
EU funding (EUR): 12870578.75
Participants: 24
Project status: CLOSED

5G!Drones aim is to trial several UAV use-cases covering eMBB, URLLC, and mMTC 5G services, and to validate 5G KPIs for supporting such challenging use-cases. The project will drive the UAV verticals and 5G networks to a win-win position, on one hand by showing that 5G is able to guarantee UAV vertical KPIs, and on the other hand by demonstrating that 5G can support challenging use-cases that put pressure on network resources, such as low-latency and reliable communication, massive number of connections and high bandwidth requirements, simultaneously. 5G!Drones will build on top of the 5G facilities provided by the ICT-17 projects and a number of support sites, while identifying and developing the missing components to trial UAV use-cases. The project will feature Network Slicing as the key component to simultaneously run the three types of UAV services on the same 5G infrastructure (including the RAN, back/fronthaul, Core), demonstrating that each UAV application runs independently and does not affect the performance of other UAV applications, while covering different 5G services. While considering verticals will be the main users of 5G!Drones, the project will build a software layer to automate the run of trials that exposes a high level API to request the execution of a trial according to the scenario defined by the vertical, while enforcing the trial’s scenario using the API exposed by the 5G facility, as well as the 5G!Drones enablers API deployed at the facility. Thus, 5G!Drones will enable abstracting all the low-level details to run the trials for a vertical and aims at validating 5G KPIs to support several UAV use-cases via trials using a 5G shared infrastructure, showing that 5G supports the performance requirements of UAVs with several simultaneous UAV applications with different characteristics (eMBB, uRLLC and mMTC). Using the obtained results, 5G!Drones will allow the UAV association to make recommendations for further improvements on 5G.

Keywords: unmanned aerial vehicle uav,unmanned aerial system uas,uas traffic management utm,network slicing,vertical trials,drone,multi access edge computing mec
A GLOBAL MOVEMENT FOR ENVIRONMENTAL JUSTICE: The EJAtlas (EnvJustice)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Spain
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-06-01
End date: 2021-10-31
Duration (months): 65.0
Total project cost (EUR): 1910811.0
EU funding (EUR): 1910811.0
Participants: 1
Project status: CLOSED

The Environmental Justice Atlas (www.ejatlas.org) is a global database built by us, drawing on activist and academic knowledge. It maps 1500 conflicts. To improve geographical and thematic coverage it will grow to 3000 by 2019. It systematizes conflicts across 100+ fields documenting the commodities at stake, the actors involved, impacts, forms of mobilizations and outcomes allowing analyses that will lead to a general theory of ecological distribution conflicts. We shall research the links between changes in social metabolism and resource extraction conflicts at the “commodity frontiers”. Also other questions in political ecology and social movement theory such as the effectiveness of direct action by grassroots protesters compared to institutional forms of contention. Does the involvement of different actors, e.g. indigenous groups, relate to different conflict outcomes? How often does the IUCN ally itself to "the environmentalism of the poor"? Do mobilizations and outcomes vary across sectors (mining, hydroelectric dams, waste incinerators) according to project differences in economic and biophysical dimensions, environmental and health risks? Are conflicts on point resources (mining, oil extraction) regularly different from conflicts in agriculture? Can we track networked resistances against Western companies, compared to those from China or other countries? Resistance to environmental damage has brought into being many local and some international EJOs pushing for alternative social transformations. We shall study the Vocabulary of Environmental Justice they deploy: climate justice, water justice, food sovereignty, biopiracy, sacrifice zones, and other terms specific to countries: Chinese “cancer villages”, Indian “sand mafias”, Brazilian “green deserts” (eucalyptus plantations). Finally, are there signs of an alliance between the Global Environmental Justice Movement and the small European movement for “prosperity without growth”, décroissance, Post-Wachstum?

Keywords: social metabolism,ecological economics,ecological distribution conflicts,ejatlas,collaborative research,social movement theory,statistical political ecology
The unity of scattering amplitudes: gauge theory, gravity, strings and number theory (UNISCAMP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Sweden
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-01-01
End date: 2023-12-31
Duration (months): 60.0
Total project cost (EUR): 1425000.0
EU funding (EUR): 1425000.0
Participants: 1
Project status: SIGNED

Scattering amplitudes are central observables in quantum field theory and provide essential information about the quantum consistency of perturbative gravity. Precise control of the physical and mathematical properties of scattering amplitudes holds the key to long-standing questions on fundamental interactions and the structure of space and time. As a concrete leap in this direction, UNISCAMP addresses predictions in gauge theories, gravity and effective theories through - the efficient computation and compact representation of scattering amplitudes and, - decoding their hidden structures & symmetries and their rich web of connections. String-theory methods will complement conventional approaches to scattering amplitudes, and I will combine the insights from - the point-particle limit of superstrings & heterotic strings and, - the recent ambitwistor strings which directly compute field-theory amplitudes. Both of them naturally incorporate the double-copy relation between gauge-theory & gravity amplitudes and extend the framework to effective field theories describing pions and other low-energy states. It is a primary goal of UNISCAMP to pinpoint the unifying principles connecting a wide range of field and string theories. My expertise in both flavours of string theories will allow to optimally exploit their fruitful synergies and to depart from mainstream approaches. Moreover, field- and string-theory amplitudes exhibit an intriguing mathematical structure: Their Feynman- and moduli-space integrals yield special functions such as polylogarithms which became a vibrant common theme of high-energy physics and number theory. As an interdisciplinary goal of UNISCAMP, I will - investigate the low-energy expansion of multiloop string amplitudes and, - extract an organizing scheme for iterated integrals on higher-genus Riemann surfaces. These research objectives should benefit from my experience in collaborations with mathematicians.

Keywords: number theory
Genetic and epigenetic resistance to oncogenic transformation of an epithelium (OncoResist)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-01-01
End date: 2022-12-31
Duration (months): 24.0
Total project cost (EUR): 159815.04
EU funding (EUR): 159815.04
Participants: 1
Project status: CLOSED

Oncogenesis is a complex multi-step process that involves the combination of genetic and epigenetic alterations for normal cells to turn into cancerous cells. Remarkably, while some strong oncogenic signals can promote transformation in some cell states, they are completely innocuous to other cell types. My aim is to study this poorly understood phenomena, being my current hypothesis, that intrinsic cell state transformation protection mechanisms are likely to exist. I will use the Drosophila eye primordium epithelium, as I have previously observed that whereas committed epithelial cells over-proliferate in response to abnormal Hippo signalling, undifferentiated progenitor cells are resistant to this transformation. To molecularly define such resilience to oncogenesis, the gene expression and chromatin accessibility profile of these two cell populations were compared. My preliminary results showed that the chromatin accessibility profile differed significantly and suggested that some pioneer transcription factors primed cells to respond to Hippo signalling. Moreover, I observed that non-coding RNAs were differentially expressed between these two cell populations. In particular, some long non-coding RNAs (lncRNAs), a class of molecules that were recently described as regulators of oncogenic signals, were particularly enriched in the progenitor cell population. More specifically, I aim to address two main questions: 1 - Is the nuclear landscape (chromatin accessibility and TFs combinations) important to control the response to high oncogenic signals? And how much of this response relies on the activity of pioneer transcription factors? 2 - What is the role of the lncRNAs in controlling cellular response to Hippo signalling? A better understanding of the intrinsic cell state protective mechanisms against transformation is likely to open important new therapeutic approaches for cancer.

Keywords: oncogenesis,cell state,resistance to transformation,netseq,chromatin landscape,pioneer factors,hippo signalling,lncrnas,transcription factors,progenitors,epithelium,differentiation
Greenhouse Robotic Worker - The first high-performance robotic system for automated harvesting of vegetables in greenhouses (GRoW)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-11-01
End date: 2022-04-30
Duration (months): 30.0
Total project cost (EUR): 2953343.75
EU funding (EUR): 2067340.63
Participants: 1
Project status: CLOSED

The goal of current project is to realize the technological scale-up of the first ever efficient and cost-effective robotic harvesting system applied to greenhouse farming of tomatoes. In fact, to date, no commercial product for automated operations on tomatoes is available because of several technological constraints linked with the unstable environment of the indoor farming, as well as with the difficulty to grasp malleable and easily damageable fruits. Metomotion has found solutions to all the challenging technical steps, thereby enabling profitable harvesting of tomatoes and making it possible to growers to harvest the fruits throughout the year and not being exposed to the labor shortage. By doing so, the harvesting costs are halved and labor reduced by 80%. In the context of thePrecision Farming approach, automation in the agricultural sector is particularly solicited and Metomotion is offering a product capable to satisfy the most compelling needs of the growers. The core innovations brought by Metomotion consist of: - Advanced 3D vision system to clearly identify ripe fruits among leaves and stems - Extensible multiple robotic arms to increase harvest speed - Touch sensitive terminals to avoid damage and loos of fruits - Fully autonomous vehicle embedding boxing system for the automated packing of collected fruits. The activities of the Phase 2 projects are related with the enhancement of the prototype performance through optimization of both hardware parts like robotic arm and AGV, as wells as related SW and User Interface. Interactions with users occurred during Phase 1 project have shown immense interest toward GRoW product from all over the world (about 100 expressions of interest collected), thus paving the basis for the successful commercialization of the product. A detailed commercialization strategy will be developed in the course of this project to allow global sales.

Keywords: robotic harvesting,machine vision,automated greenhouse management,precision farming
Reversing Controlled Radical Polymerisation: Towards Complete Depolymerisation (DEPO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Switzerland
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2020-09-01
End date: 2025-08-31
Duration (months): 60.0
Total project cost (EUR): 1491260.0
EU funding (EUR): 1491260.0
Participants: 1
Project status: SIGNED

Controlled radical polymerisation has revolutionised the field of polymer chemistry by allowing access to the synthesis of a wide range of materials with controlled molecular weight, dispersity, architecture and end-group fidelity. Although thousands of papers have reported on optimising the polymerisation parameters, very few reports have focused on reversing controlled radical polymerisation. This is a significant oversight, as controlled depolymerisation has the potential not only to reveal intriguing avenues of research, but also to pave the way for promising applications including innovative polymer characterisation methodologies. The overall vision of DEPO is to develop a universal, quantitative and controlled depolymerisation of polymers (i.e. converting polymers back to the corresponding monomers) synthesised mainly by controlled radical polymerisation. Although this strategy will initially be developed for atom transfer radical polymerisation (ATRP) systems, it will be expanded to include reversible addition-fragmentation chain-transfer (RAFT) and nitroxide-mediated polymerisation (NMP) protocols. Widely-used polymers synthesised by other methods such as polystyrene will also be modified to permit for depolymerisation. Importantly, this approach will operate at room temperature and will be applicable to a range of polymer classes and architectures (block copolymers, stars, etc.). The fundamental outcomes of this research will inform depolymerisation design strategies and will pave the way for additional opportunities such as advanced polymer characterisation.

Keywords: atom transfer radical polymerisation,reversible addition,fragmentation chain transfer,controlled radical polymerisation
Opticon RadioNet Pilot (ORP)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Integrating activities and infrastructures
Action type: Research and Innovation actions
Countries involved: Spain,South Africa,Australia,Germany,Germany,Spain,Spain,Spain,Italy,Belgium,Finland,Poland,Poland,Sweden,Greece,Greece,Hungary,Latvia,France,France,France,France,United States,Netherlands,Netherlands,Netherlands,Denmark,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom,Portugal,United Kingdom,United Kingdom
Call: Pilot for a new model of Integrating Activities (H2020-INFRAIA-2020-1, 2020)
Start date: 2021-03-01
End date: 2025-02-28
Duration (months): 48.0
Total project cost (EUR): 15024638.0
EU funding (EUR): 15000000.0
Participants: 40
Project status: SIGNED

For more than two decades, the EU has been supporting free transnational access (TA) to existing national research infrastructures (RI). In particular, the optical/infrared and the advanced radio astronomy communities are now recognised as TA flagship communities. Their telescopes and instrumentation complement each other with respect to wavelength coverage, as well as spectral, spatial and time resolution, and therefore together form a cohesive suite of RIs that made ground breaking discoveries possible and thus strengthened Europe's leading role in international science. While scientists more and more rely on multi-wavelength and multi-disciplinary access to the best RIs, there is a quest by the RI providers for a sustainable funding scheme for TA, since establishing and maintaining outstanding RIs requires considerable resources. In this pilot, the best research institutions from both communities will combine their efforts to further improve and harmonize their services and to make best use of their RIs, allowing mutual and TA to telescopes, telescope networks, and data archives. This will facilitate multi-wavelengths and time-domain studies. TA shall be simplified by the development of a common proposal submission tool. Improved instruments, adaptive optics, and software to deliver science ready data products will boost the performance of our RIs. This pilot will address imminent threats to astronomical research from satellite mega constellations and commercial radio emitters, and finally, it will develop plans for a long-term mutual relationship and for a continued funding of TA beyond this pilot.

Keywords: optical astronomy,radio astronomy,astrophysics,physics,research infrastructures,ground based telescopes