Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Repetition and Seriality in the Age of Television Studies 3.0 (REPEAT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2011-IOF, 2011)
Start date: 2012-06-01
End date: 2015-05-31
Duration (months): 36.0
Total project cost (EUR): 266289.0
EU funding (EUR): 266289.0
Participants: 1
Project status: CLOSED

Researches in Media and Television Studies until today focus either on media industry, content, audiences or media technology. Recent developments regarding the globalization of television formats and the intermedial distribution and reception of television content via the internet and mobile media have been analyzed merely with regard to audience reception and participation. The research project ‘Repetition and Seriality in the Age of Television Studies 3.0’ will integrate all four dimensions of television to give an example of television in times of current global and intermedial transformations and will explore how these challenges effects European media landscape. This research objective should be achieved by the analysis of the recent phenomenon of transnational adaptations of television series in the US and Germany. REPEAT will analyze for which reasons television series are adapted by national channels or distributed globally, how the content and format of the series are transformed by transnational and intermedial adaptations and the series reception by audiences and critics. In comparison to preceding researches REPEAT will account for the multidimensional aspects of television productions by developing and extending the new interdisciplinary research methodology ‘Television Studies 3.0’ that is able to explain major current global challenges in media technology and its influence on society.

Keywords: social sciences,humanities
Human-Information Interaction in 3D Virtual Environments (HII3D)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Hungary
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-06-01
End date: 2013-08-31
Duration (months): 15.0
Total project cost (EUR): 122327.75
EU funding (EUR): 122327.75
Participants: 1
Project status: CLOSED

The proposed research would allow the Fellow to bring her expertise in Human-Information Interaction (HII) to a unique joint project of the Department of Ergonomics and Psychology (DEP) at the Budapest University of Technology and Economics (BUTE) in Hungary and the 3DICC Laboratory of the Computer and Automation Research Institute of the Hungarian Academy of Sciences (CARI - HAS) and the BUTE. In the innovative proposed project, the Fellow will study HII in novel 3D virtual environments. Two related research subprojects are proposed: 1) the study of collaboration and information sharing in geographically dispersed, networked 3D immersive environments 2) the development and evaluation of 3D information displays and visualizations. The research will take advantage of the unique hardware and software infrastructure and expertise of the 3DICC and the DEP BUTE. The outcomes will include: 1) significant and high quality research results relevant for the EU Future Internet priorities and disseminated through joint publications by the Fellow and the European hosts, 2) the potential for developing marketable solutions by the 3DICC’s Hungarian industry partners, 3) the development of strong, sustainable collaboration between the two Hungarian institutions and the Fellow’s United States-based home institution, 4) significant and applicable knowledge transfer to the European host institutions and Europe.

Keywords: human-computer interaction,virtual reality,human-information interaction,collaborative information seeking,information displays
Art and Death in Neolithic Europe (ADINE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-09-01
End date: 2014-08-31
Duration (months): 24.0
Total project cost (EUR): 209033.4
EU funding (EUR): 209033.4
Participants: 1
Project status: CLOSED

In Neolithic Western Europe, monumental tombs were frequently decorated with engraved and painted art. Archaeologists have rarely asked why there is such an association between art and death. How was art used to create spaces appropriate for the performance of deathways? Since the 1960s research on this art has stagnated both theoretically and methodologically, leaving this important question unanswered and unanswerable. The ADINE project proposes a comprehensive study of how art was created and used in the Neolithic tombs of Sardinia, which are by far the largest group of decorated tombs in Europe but also the least studied. The project has three research objectives. The first is to document unpublished decorated tombs. We will use both standard techniques and several innovative photographic techniques for revealing poorly visible art and analysing the technique and sequence of the art’s manufacture; we will also analyse the spatial organisation of art inside tombs and the regional distribution of decorated tombs using statistics and GIS. The second objective is to place Sardinian art into its larger historical context within the major tomb art traditions of Neolithic Western Europe. These two goals are aimed at answering the research question posed above. The third objective is to build up a new generation “total recording” methodology for rock art sites by testing and developing together a suite of complementary methods (the photographic techniques noted above, portable digital microscopy, and non-destructive, portable XRF spectroscopy to identify painted areas and pigments). The project, hosted at Cambridge University, includes a strong training programme for the coordinator, and will help maintain Europe’s pre-eminence in rock art research and theoretical archaeology. Its impact may extend beyond academia to the large worldwide public interested in rock art and to organisations responsible for cultural heritage development and management of rock art sites.

Keywords: neolithic europe,sardinia,hypogea,rock art,death,spatial analysis,gis,multivariate statistics,digital microscopy,xrf spectroscopy.,humanities
Identification and characterization of factors involved in chromosome organization and septum positioning in bacteria (COSP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2013-02-01
End date: 2015-01-31
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 1
Project status: CLOSED

The cell cycle is one of the most pivotal and fundamental processes in biology and encompasses a set of inter-related events, most prominently, chromosome replication, chromosome segregation and cell division. Each of these steps is highly complex, and bacterial cells offer the opportunity to study cell cycle processes in a simplified, relatively tractable context. Investigation of the bacterial cell cycle would not only be of benefit to basic understanding of this process in living organisms in general, it is also highly relevant to pathogenesis and antibacterial drug development. Bacillus subtilis is a particularly good model for studying the bacterial cell cycle for several reasons. First, it is highly tractable as an experimental system. Second, the asymmetric cell division used during the early stages of sporulation, provides certain important experimental opportunities. Third, research on the cell cycle of B. subtilis is at the frontiers of our knowledge about this process. By setting up genetic screens based on asymmetric cell division during sporulation in B. subtilis, this project aims to discover novel factors involved in proper chromosome organization and septum positioning, two important elements of the cell cycle. In addition, chromosome condensation will be studied in more detail using methods based on chromosome conformation capture (3C) technology. By exploiting the wide array of molecular and cell biology tools and techniques available in the host lab, the function of the identified factors will be further investigated. Overall, this project is expected to yield novel insights into the bacterial cell cycle, especially with regard to chromosome structure and placement of the septum during cell division. Also, the project and research environment offer the researcher an excellent opportunity to develop scientifically and prepare for a leading independent position.

Keywords: bacteria,bacillus subtilis,cell cycle,cell division,sporulation,chromosome organization,septum placement.
Hybrid Photonic Metamaterials at the Multiscale (HYPHONE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-10-01
End date: 2014-12-04
Duration (months): 24.0
Total project cost (EUR): 228082.2
EU funding (EUR): 228082.2
Participants: 1
Project status: CLOSED

In recent modern optics, two rapidly developing branches can be identified: (i) photonics, which studies materials structured on a mesoscopic (micrometer or wavelength) scale, and (ii) optics of metamaterials, which are structured on a nanometer (deeply subwavelength) scales. In both these branches, revolutionary degree of control over light propagation and light-matter interaction has been achieved. However, they still remain relatively isolated fields of study. This project is aimed at developing a unified theoretical paradigm of hybrid multiscale photonics by combining the knowledge of photonics, plasmonics, and optics of metamaterials. It is expected that synergies between photonic band gap phenomena and exotic plasmonic excitations present in metamaterials will significantly enhance the possibilities for controlling the flow of light and tailoring light-matter interaction at the nanoscale. Central to the project are hybrid photonic/metamaterial systems where the elements (e.g., layers) are arranged in a periodic or aperiodic “superstructure” and themselves contain metamaterials “substructured” on a deeply subwavelength scale. The studies will start with simple geometries such as metal-dielectric multilayers with micrometer-scale superstructure and nanometer-scale substructures, moving on to more complicated 2D/3D systems based on nanowires and nanoparticle clusters. The resulting theoretical concept, applied to hybrid photonic/plasmonic/active systems (such as metal nanoparticle arrays embedded in polymer matrices doped with dye molecules), will be used to design novel plasmonic materials with low loss and/or optical gain. It will also lead to novel physical concepts such as random spasers or deterministically aperiodic photonic/plasmonic nanolasers, with applications in efficient on-chip frequency/polarization filtering, on-chip label-free sensing, and on-chip device-enhanced light-matter interactions.

Keywords: optics,photonics,plasmonics,metamaterials,multilayers,nanoparticles,multiscale analysis,light-matter interaction
The Molecular Genetics of Heroin Dependence (HEROGEN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-10-01
End date: 2014-09-30
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 1
Project status: CLOSED

The use of illicit psychoactive drugs such as opioids, cocaine, amphetamines, ecstasy and cannabis remains at high levels. Globally around 15 million people use heroin and the societal cost is high due to lost productivity, criminal activity and medical care. Although there are established risk factors for drug abuse, including urban poverty, mental illness, parental alcohol and drug abuse, there is a strong familial aspect to drug abuse. Family, twin and adoption studies have demonstrated that genetics factors play a major role in the etiology of addictive disorders. Studies in large twin samples suggest that a large contribution to liability of risk of becoming dependent on heroin is due to genetic effects. So far, most of the genetic studies on heroin abuse have tested candidate genes which have been selected on the basis of perceived functional relevance to heroin abuse. Thus, most candidate genes have been those encoding neurotransmitters and neuroreceptors, particularly neuronal systems thought to be critical to heroin addiction, for example, systems modulating the euphoric and dysphoric symptoms. In general, the search for risk genes has produced inconclusive results due to sample issues and the limited number of variants tested. The aim of this proposal it to conduct a focused study of heroin dependence and related phenotypes by overcoming the limitations of previous studies. This will be done in the following ways: 1) Utilize a large, ethnically homogeneous sample to identify risk variant through a cost-effective and efficient Genome-wise Association Study using pooled DNA. 2) Conduct association analysis with heroin dependence as well as related phenotypes 3) Perform allele specific functional studies on the top risk genes identified 4) Use bioinformatics to identify risk pathways This is the first comprehensive study of heroin dependence and related traits and results from this study will be vital for future studies.

Keywords: heroin molecular genetics pooled genome-wide association study allele specific expression risk genes risk pathways
Evolutionary Determinants of Influenza Virus Pathogenesis and Tissue Tropism (INFLUENZA TROPISM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-11-01
End date: 2014-10-31
Duration (months): 24.0
Total project cost (EUR): 183805.8
EU funding (EUR): 183805.8
Participants: 1
Project status: CLOSED

Influenza A virus bears high morbidity and mortality burdens in humans following yearly seasonal epidemics and occasional yet potentially devastating pandemics. These burdens are a result of disease severity following infection in individual hosts, and the size of influenza epidemics/pandemics at the population level. The relationships and feedbacks between influenza virus pathogenesis at the individual host level and influenza virus epidemiology at the population level are ill understood. Influenza virus tissue tropism contributes to determining which regions of the respiratory tract (from nasal cavity to deep lungs) are infected. The spatial location of influenza virus infection along the human respiratory tract is a determinant of the virus’ pathogenicity and transmissibility. While disease severity increases deeper down the respiratory tract, transmissibility appears favoured higher up. Both pathogenicity and transmissibility, associated with tissue tropism, contribute to the virus reproductive fitness, defining the size of the epidemic or pandemic. Therefore, strong selective pressures acting within hosts and at the population level likely shape tissue tropism to maximize influenza virus reproductive fitness. The aim of the project is to characterize these selective pressures and their interplay at the interface of within- and between-host dynamics, by combining experimental work and mathematical modelling. Key objectives are to determine the selective pressures associated with transmission and pre-existing immunity on influenza virus tissue tropism in an experimental setting; and determine the mutual interactions of these selective pressures by use of combined within- and between-host mathematical models. Modelling skills and knowledge will be transferred by the candidate to the European host. This project intends to clarify the cross-scale dynamics of influenza virus to better characterize and predict influenza morbidity and mortality burdens.

Keywords: infections,zoonesis,virology,evolutionary biology
Modelling and geochemical implications of intra-arc melting: consequences for the composition of the continental crust (MELTARC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-10-01
End date: 2014-03-31
Duration (months): 18.0
Total project cost (EUR): 144466.65
EU funding (EUR): 144466.65
Participants: 1
Project status: CLOSED

Arcs are expected to be the fundamental brick of the Continental Crust (CC). The main problem with this hypothesis is that the bulk CC has an andesitic composition while most arcs are formed by successive inputs of basaltic magmas. If island arcs accretion is indeed the main mechanism of crustal growth, one must explain how arcs can reach an intermediate composition and if these processes are effective in the nature. Intra-arc differentiation takes place in their lower crustal section. Removal of magmatic cumulates is not a sufficient process to drive the bulk composition of island arcs towards intermediate ones. Because melting and dehydration lead to the production of dense iron-rich melting and/or dehydration residues, it could causes delamination of mafic-ultramafic rocks into the mantle due to gravitational instability in the lowermost arc crust. Melting at the basis of arcs is most probably a necessary conditions to evolve towards andesitic bulk composition. The mechanisms of arc differentiation and their consequences are still poorly understood; this is due to the scarcity of exhumed section of arcs that have preserved evidences for lower crustal melting and/or dehydration. This project will focus on selected samples from well-constrained Precambrian and Phanerozoic exhumed arc sections. The main objectives are to: (i) quantify the geochemical differentiation induced during partial melting by directly analysing and modelling the composition of melts and residues sampled in exhumed arc roots; (ii) model the P-T-X conditions of intra-arc differentiation and to establish the mechanisms responsible for such a process; (iii) evaluate the causes and consequences of melting on the bulk structure, composition and stability of arcs by numerical modelling. The results of this study will be used to evaluate if delamination and foundering of dense residues at the base of arcs is a viable mechanism to change their bulk composition towards the one of continental crust.

Keywords: petrology,geochemistry,continental crust composition and growth,island arcs,modeling,partial melting,planetary differentiation
Development of a fully automated, integrated solution that can support a wide range of complex sample preparation protocols (SPCARD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2013-01-01
End date: 2014-12-31
Duration (months): 24.0
Total project cost (EUR): 235000.0
EU funding (EUR): 235000.0
Participants: 1
Project status: CLOSED

A growing number of molecular diagnostics (MDx) tests help identify risk factors for disease, characterise disease status and subtype, and determine when and which therapeutic intervention is needed. However, MDx tests are labour intensive, require specialised infrastructure and require highly trained personnel. Only a limited number of MDx systems offer sample preparation but often require manual intervention or are targeted at high-throughput analysis. Integrated cartridges for point-of-care solutions today cannot support a wide range of complex sample preparation protocols. The aim of this project is to develop for the first time a fully automated, integrated solution that can support a wide range of complex sample preparation protocols. The integrated cartridge will be developed so that it incorporates all necessary functionalities for the typical biochemical steps of such sample preparation protocols. Biocartis, a biotech company, is engaged in the development of novel diagnostic technology platforms for low to highly multiplexed detection of molecular-based biomarkers. This fellowship will provide Dr Penterman with the opportunity to experience and learn more about the development phases i.e. implementing a rapid prototyping protocol for the introduction of different functionalities to support different biochemical steps, prototype design, production and assembly. An understanding of the functional testing that will be required to validate the prototype for a first application (Pathogen DNA enrichment) will be necessary to develop the cartridge to meet the needs of the complex protocol. His geographic transfer from The Netherlands to Belgium and from a large multinational company to a start-up SME reflects genuine mobility. The training offered will allow Dr Penterman to evolve from a pure research scientist, with the longer term potential to evolve into a position of management, with the necessary expertise to identify strategically important projects.

Keywords: microfluidics,lab-on-chip,sample preparation,molecular diagnostics