Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A self-esteem process framework of the transition to work (Self-EsteemProcesses)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-01-01
End date: 2022-09-26
Duration (months): 24.0
Total project cost (EUR): 175572.48
EU funding (EUR): 175572.48
Participants: 1
Project status: CLOSED

The transition into the workforce is a major developmental milestone in young adulthood that brings tremendous life changes and sets the course for future development. This project aims to examine the impact of the work transition on self-esteem, a key personality characteristic responsive to experiences of success and failure. Self-esteem is among the strongest predictors of major life outcomes, including mental and physical health, economic prospects and longevity. Long considered to be highly stable across the lifespan, new evidence shows that self-esteem can change in response to life events. Yet, knowledge about the processes that elicit change is scarce as research relies on few assessments and theories mute on mechanisms. The central aim of this project is to advance the understanding of the mechanisms underlying self-esteem change by closely dissecting the macro- and micro-level processes. I have developed a framework that integrates different theoretical approaches to understand self-esteem processes. It has three aims: (1) To study the macro-level contextual changes, (2) To examine the micro-level processes of thoughts, feelings, and behavior evoked through the individuals’ daily interaction with the environment and (3) to examine how the resulting changes in state self-esteem (short-term changes) get manifested in trait self-esteem (long-term changes). A comprehensive multi-method approach will be used that combines high-density in-situ assessments of daily life using a novel smartphone technology and physiological assessments (to illuminate the short-term processes) with multi-wave self- and observer-reports over a longer time scale (to examine developmental change). This ambitious, innovative project will provide novel insights into the mechanisms of self-esteem development in a major life transition. It will have a strong impact on the field and has the potential to inform policy allowing for tailoring interventions to promote successful development.

Keywords: personality development,self esteem development,lifespan development,life transitions and the transition to work,daily diary longitudinal data and experience sampling method
Cross-Coupling (C-X): Pioneering Mild Aqueous Cross-Coupling Methodologies to Enable Selective Functionalisation and Diversification of Halogenated Natural Products (C-Xaq)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-01
End date: 2017-04-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Natural Products (NPs) are key to medicine, yet the generation of analogues of these important compounds can often be challenging. I propose to investigate an exciting new approach to NP analogues pioneered by the Goss lab. By developing new, mild, aqueous and selective cross-coupling chemistries I will enable the selective diversification of organic molecules, and in particular NPs, containing carbon-halogen bonds. With my expertise in organometallic chemistry and computational chemistry and in collaboration with the Goss lab, we are poised to bring significant advance to this new field of research. Over 5000 halogenated NPs have been isolated and identified to date, presenting a series of attractive test-beds for this proposed research. Additionally, with the advent of synthetic biology, it has recently been possible for the Goss group and others to engineer new to nature NPs containing halogen handles. The Goss group demonstrated selective functionalization of these NPs developing and using mild and aqueous Suzuki Miyaura cross-coupling conditions. Building upon this success, I will develop methodology to enable, under mild aqueous conditions, a greater diversity of cross-coupling reactions of aryl halide containing small molecules and then NPs to be employed. I will then embrace the challenge of the selective functionalization of the less reactive vinyl and alkyl halides, first in the presence of small molecules and then in the context of NPs. My reaction design, in this challenging area, will be informed by recent literature precedent, and my own DFT calculations. Success will both enable access to libraries of previously inaccessible NP analogues and provide the first steps toward being able to carry out these chemical reactions in tissues and perhaps even in live organisms in a bioorthogonal manner.

Keywords: natural product analogue generation through developing and utilizing cross coupling chemistry,underpinned by dft and pca
Multi-Potent Polymer Precursor approach for novel conjugated polymers (MP3)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-02-01
End date: 2023-01-31
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: CLOSED

In this proposal, I introduce a new approach for the synthesis of conjugated polymers comprising anthraquinone and anthracene units in the molecular backbone and their use in ultra-thin film organic electronics. The preparation of these materials is possible via a common multi-potent precursor polymer obtained easily from anthraquinone via nucleophilic attack of an acetylide on the 9,10 position (yielding in a propargyl alcohol fragment) and subsequent polymerization via classic aromatic polymerization routes. Such precursor – whose chemical and processability properties can be tuned by modification of the propargyl alcohol moiety – yields both the final fully-conjugated anthraquinone and anthracene polymers by loss of acetylene or reduction respectively. In this way it is possible to overcome the limitation often fund in the synthesis of high-molecular weight fully-conjugated polymers. Moreover, one can introduce responsive functionalities to trigger the last step using diverse chemical, thermal, and photo stimuli, therefore allowing the realization of fine patterns and architectures via ink-printing, laser writing, and lithographic approaches. I propose to apply this methodology for the realization of ultra-thin inherently-conformable organic electronics devices that can find use in sensing, healthcare, and as electrode materials. Thanks to the orthogonality of the transformations introduced above, the approach described herein allows the preparation of up to three different phases from a single processable material, thus increasing the level of complexity achievable in thin-layer devices.

Keywords: conjugated polymers,precursor chemistry,organic electronics,organic semiconductors,thin layer devices,responsive materials,anthraquinone,acenes
Twinning in Research and Education to improve survival in Childhood Solid Tumours in Lithuania (TREL)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Germany,Italy,Austria,Italy,Belgium,Lithuania,France,Netherlands,Denmark
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2021-01-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 898927.5
EU funding (EUR): 898927.5
Participants: 10
Project status: SIGNED

Vilnius University Hospital Santaros Klinikos (VULSK) acts as a coordinator of the TREL (Twinning in Research and Education to improve survival in Childhood Solid Tumours in Lithuania) project that aims to enhance translational, clinical and late-effect research in paediatric solid tumours (ST). The project concept is based on the existing shortcomings in paediatric oncology at VULSK and Lithuania – scarce research indicators and inferior survival rates in children with ST. TREL has a goal to increase scientific excellence in the most common paediatric ST (brain tumours, neuroblastoma and renal tumours). VULSK and 8 leading research intensive institutions each covering different areas of the project activities according to their expertise form the TREL consortium. TREL will be delivered in 7 working packages addressing training in tumour specific laboratory research and clinical trials, cross-cutting education on genome-wide sequencing and treatment innovations, enhancing skills in observational studies on the quality of survivorship including fertility preservation and research methodology as well as project and innovation management. Training exercise will focus on the implementation of secondments of VULSK staff to the partner premises, organisation of multidisciplinary transfer-of-knowledge meetings, and participation in strategic scientific meetings corresponging objectives of each working package. As a consequence of the twinning activities with internationally-leading research active counterparts VULSK will improve its research profile and reputation, enhance international, regional and national visibility and competitiveness. Fostering of existing and establishment of new networking channels will facilitate incorporation of VULSK professionals to the ongoing collaborative projects that will improve research indicators of individual researchers and VULSK as well as will increase survival rate of children with ST in Lithuania in a long-term perspective.

Keywords: training,oncology,genetics,clinical trials,widening countries
Reducing networking gaps between Rīga Stradiņš University (RSU) and internationally - leading counterparts in viral infection-induced autoimmunity research (VirA)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Germany,Italy,Israel,Latvia
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2020-12-01
End date: 2023-11-30
Duration (months): 36.0
Total project cost (EUR): 899992.5
EU funding (EUR): 899992.5
Participants: 4
Project status: SIGNED

The specific challenge of VirA Twinning project is to enhance networking activities between the Riga Stradins University (RSU) located in Latvia as a Widening country and internationally-leading counterparts at EU level, in the field of autoimmunity research. RSU is an institution that has proven itself over several decades on a local and regional level as an important island of research excellence in viral infection-induced autoimmunity research. Further raising the research excellence requires widening the network and establishing closer cooperation with global leaders in science, sharpening the institutional profile of RSU. Project aims at strengthening the close scientific cooperation with counterparts: in Italy - University of Ferrara, in Germany - Ulm University, and in Israel - Tel-Aviv University. The partner universities are the excellence centres (world leaders) that are forerunners in immunology, virology, morphology and clinical data management and modelling, and are capable of inspiring positive change in the research field and significantly influence future developments at RSU via joint activities. Systemic autoimmune diseases (SAD) are a significant cause of morbidity and mortality worldwide, creating a challenge for researchers and clinicians to find evidence-based solutions for SAD diagnostics, treatment and prevention. Due to the complexity of autoimmune disease research, which requires multidisciplinary approaches, a problem is insufficient research capacity at low-performing EU Member State research institutions. Research capacity, able to deliver precise and early diagnostic is of high importance to move towards the development of methods for personalized medicine and better understanding of triggers and mechanisms in autoimmunity, leading to better understanding of chronic diseases and comorbidities and searching for therapy options. VirA project will optimally address the challenges and strengthen the ERA in autoimmunity.

Keywords: rheumatoid arthritis,autoimmune thyroiditis,persistent viral infections,autoinfectome,multiplex technologies,diagnostic algorithm
A Network Science Approach to Social Cohesion in European Societies (PATCHWORK)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Spain
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2021-10-01
End date: 2026-09-30
Duration (months): 60.0
Total project cost (EUR): 2447501.0
EU funding (EUR): 2447501.0
Participants: 1
Project status: SIGNED

As European societies are becoming increasingly unequal, diverse, and polarised, concerns about their cohesion are growing. In this light, it is surprising that social cohesion research has almost entirely ignored one of its core dimensions: relationships. Broad acquaintanceship networks, which connect each individual to hundreds of others through both intimate and superficial relationships, have long been assumed to bind societies together and provide a sense of community and solidarity. Nonetheless, they have hardly been studied empirically due to the technical complexity that the comprehensive study of society-wide networks involves. This project will develop a ground-breaking, network-scientific approach to social cohesion. After designing a theoretical framework for the structural cohesion of societies, it develops a new methodology to study structural cohesion empirically, hybridising two strands of network research in an unprecedented way. The methodology will be implemented in a large-scale, cross-national European survey administered to representative samples of the populations. The survey estimates are used to simulate society-wide networks, to explore resulting macro-level structures. These macro-level structures are then used to specify agent-based models to study in more depth how broad acquaintanceship networks influence subjective manifestations of cohesion. For the first time, we will know how cohesive broad acquaintanceship networks are across categorical fault lines of citizenship, social class, religion and political orientation for five societies, how real-life inter- and intragroup relationships cluster to form network constellations that expose individuals in unique ways to other social groups, and how these constellations shape subjective manifestations of cohesion such as tolerance, trust, and acceptance of diversity.

Keywords: analytical sociology,social networks,social cohesion,social integration,social influence,personal networks
Highly stable glasses applied for lithium ion battery electrolytes (HS-GLASSion)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-08-01
End date: 2017-07-31
Duration (months): 24.0
Total project cost (EUR): 172800.0
EU funding (EUR): 172800.0
Participants: 1
Project status: CLOSED

Lithium ion batteries (LIB) with a solid-state electrolyte component is one of the much desired goals for rechargeable energy sources since they provide with high safety, high reliability and high energy density. Inorganic glass-based electrolytes are very promising materials due to their higher ionic conductivity when compared to crystalline alternatives. Nevertheless, important concerns still have to be resolved and optimized. For instance, ionic conductivity in glass-based electrolytes continues to be poor compared to liquid electrolytes and their stability still lacks of long lifetime capability. In general, necessary innovative scenarios are needed as the next step forward in current thin film battery research. In order to improve performance and solve these issues in LIB's we propose, as the main purpose within HS-GLASS+ion, the addition of a new class of materials, the so called highly stable glasses (HSG). These glasses can achieve remarkable properties when prepared through vacuum deposition processes when tuning several parameters during film growth. This new discovery is well considered as an important development in glasses and supercooled liquids but still unknown in the area of energy storage. HSG’s have higher densities which can help to easily create large homogeneous areas without any performance threatening artefacts. They are more resistant to temperature and vapor uptake which will increase chemical and structural stability of electrolytes. The lack of grain boundaries but the coinciding existence of short-range order will modify Li+ ion mobility achieving properties that have not yet been explored in battery research. The ability of tuning stability on HSG’s will help boost interface engineering through gradient compositions between the electrodes and electrolyte. The outstanding properties of HSG's will help fulfill thin film technology needs and battery research current requirements.

Keywords: lithium ion batteries,stable glasses,solid state,electrolyte,thin films,ionic conductivity
Asymmetric Catalysis with Chiral Silylium Cations (SILYCAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-02-01
End date: 2019-01-31
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

In the frame of this research program, carried out at the Institute of Molecular Sciences (ISM) within the University of Bordeaux (UB), we propose the development of new powerful Lewis acid catalysts for asymmetric synthesis. The activation of small molecules (H2, CO2) and less-reactive compounds in catalytic processes is one of the central tasks of modern synthetic chemistry. This task is of fundamental and practical interest as well as of environmental significance, a central issue for our society. Purpose of the suggested research proposal is the synthesis of tailor-made chiral silyl cationic compounds with exceptional but controlled reactivity. Various molecular test systems are suggested to identify the parameters that allow efficient control over the reactivity of these silyl cations. These model systems will be applied as catalysts in organic model reactions including Diels-Alder, Mukaiyama and hydrogenation processes. The major objective of this proposal is the generation and studies of chiral silyl cations and their weakly coordinating anions in an effort to combine their inherent high reactivity with enantioselective processes. The use of chiral silyl cations as efficient Lewis acid catalysts in organic transformations should have significant impact on enantioselective organic synthesis. Key objectives of this research program are the development of new strong activators for an efficient synthesis of chiral molecules and the training of future leading experts in the field of catalysis, a domain in which Europe must remain competitive in the 21st century as the demand for new chiral molecules and materials is increasing in domains ranging from health to energy.

Keywords: silylium ions chemical bond activation,organocatalysis enantioselective processes
Healthy crop, Healthy environment, Healthy finances ... through Optimization (H3O)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: Spain
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-2-2014, 2014)
Start date: 2015-06-01
End date: 2017-05-31
Duration (months): 24.0
Total project cost (EUR): 1307569.7
EU funding (EUR): 915298.79
Participants: 1
Project status: CLOSED

Pulverizadores Fede is a technology leader in the production of agricultural machinery for vertical crops found, for example, in orchards and vineyards. As such, we are well positioned to contribute to resource-efficient eco-innovative food production, which is not only good for the environment but is also key for the agricultural sector’s competitiveness with a clear European dimension. Cropland covers almost 25% of the EU (4.4 million of Km2) and most of that area is subject to phytosanitary treatment. With the two year H3O project, we bring a completely new generation of plant protection product application devices (sprayers) to market, reducing the amount of product that is released into the environment by 50%. Further, the fine grain adaptation allows to save 38.5% diesel. For a small farmer with 10 hectare of vertical crop this results in product and fuel savings worth 4630 Euros annually. Moreover, the project is meeting key requirements of the EU Directive 2009/128/EC on sustainable use of pesticides and is in line with the food chain industry standard GLOBAL G.A.P.

Keywords: reduction of pesticide use,food chain traceability,low drift spraying equipment,farmers profitability,sales triplication,human health,environment protection,farm management