Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Analog Polariton Simulators (ANAPOLIS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: France
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Many physical systems in nature must be described using a huge number of coupled degrees of freedom. Treating these problems on a classical computer leads to computation times growing exponentially with the system size. Analog simulators are well-controlled systems to which a complex problem can be mapped, and from which the physics can be experimentally readout. Here, we want to develop powerful analog simulators based on semiconductor cavity polaritons, light-matter quasi-particles that have appeared as a versatile platform to explore the physics of bosonic open systems. Using the fine control we now have in polariton lattices, ANAPOLIS opens the door to the simulation of a large class of systems subject to external drive and dissipation, a regime hardly explored in other platforms. Out-of-equilibrium condensation, giant Kerr non-linearity, optical driving of steady-states are the ingredients we will use in ANAPOLIS to explore three scientific objectives: 1.We will study phase fluctuations in polariton condensates and map the system to the Kardar-Parisi-Zhang equation, which describes many dynamical nonlinear systems. In 2D, solving this equation is a challenge raising open questions that no experimental platform has addressed so far. 2.We will resonantly drive polariton lattices with elaborate phase patterns to simulate the physics of charged particles in a magnetic field. Optically inducing complex valued hoppings, we will tailor topological properties for the Bogoliubov excitations, and explore non-linear physics on top of a topological superfluid. 3.We will use cavity lattices under quadratic drive to emulate the physics of the quantum transverse Ising model in a driven-dissipative context. We will use this simulator to find the steady state of the system and explore quantum magnetism and dissipative phase transitions. ANAPOLIS will provide unique opportunities to address stochastic phenomena, nonlinear and many body physics in a driven-dissipative context.

Keywords: exciton polaritons,kpz physics,topology
Energy Transitions and the Rise and Fall of Great Financial Centers (ENFIN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-07-01
End date: 2028-06-30
Duration (months): 60.0
Total project cost (EUR): 1499749.0
EU funding (EUR): 1499749.0
Participants: 1
Project status: SIGNED

For all their differences, modern nation-states are both the energy transition leaders and financial leaders of their time. They are also home to our great financial centers (GFCs), and the question of the rise and fall of GFCs is a matter of longstanding debate. Existing explanations struggle to explain the timing and forecasting of the rise and fall of GFCs in a systematic manner. No researcher has connected the dots between energy transitions, financial transitions, the role of financial systems, and the rise and fall of great financial centers. My nontraditional hypothesis is that energy transitions drive financial transitions and GFCs. The core aims of ENFIN are: Create a new field of research integrating elements from comparative institutionalist literature, socio-technological transition research, and research on financial centers. a) Integrate the role of energy transitions in the literature on financial centers. I will use cross-national and cross-temporal comparisons to establish the sequences and relationship between energy transitions and financial transitions. b) Lift the analytical power of socio-technological transition research with regard to the reciprocal logic of low-carbon energy and green finance transitions. I will examine causal mechanisms through inductive process tracing on evidence about the pressures arising from energy transitions on existing financial structures and socio-economic actors’ responses. c) Investigate the role of institutions in the relationship between green-energy transition and future financial leadership. I will conduct σ-convergence analysis to develop a global database to compare green financial standards by countries and a multigroup latent growth curve (LGC) model to compare and predict growth trajectories of multiple groups (e.g., coordinated market economies, capital market economies, and state driven economies) in financial systems over time.

Keywords: energy transitions,infrastructure investments,path dependency,financial transitions,innovation,market capitalization,financial systems,great financial centers,green financial centers,green financial standards
Optimized huMan iN vItro vascularized 3D Brain tissUe model for Studying neurodegeneration (OMNIBUS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 202125.12
EU funding (EUR): 202125.12
Participants: 1
Project status: SIGNED

Neurodegeneration is a major health concern affecting millions of individuals in Europe, with this number constantly increasing as population ages. A cure for this spectrum of conditions is still missing, in part due to differences between available experimental models and human pathophysiology. My aim is to develop an in vitro 3D brain tissue model that combine the major brain cell types (obtained from human induced pluripotent stem cells - iPSCs) also including vascular cells, for better resembling the human brain. Currently, the available in vitro 3D brain tissue models lack a functional vasculature with brain-specific features, thus limiting the possibility to study (vascular-related) pathophysiology. Transplantation is still the only strategy leading to an extensive and functional vascularization of 3D brain models. I will combine -omics technologies for optimizing the vascularization of 3D brain tissue models. First, I will investigate whether factors released by iPSC-derived neurons and their precursor cells can promote vessel formation by the endothelium. Second, I will determine which changes occur in 3D brain tissue models upon transplantation compared with in vitro culture. I will then reproduce the identified drivers of this process for obtaining a fully in vitro vascularized 3D brain tissue model, without the need for transplantation. Finally, I will show that the manipulation of this vascularized 3D models allows for studying the vascular contribution to mechanisms of neurodegeneration and for evaluating possible intervention strategies. The optimization of in vitro vascularized 3D brain tissue models will facilitate reducing costs and number of experimental animals. Also, their ease of manipulation and high-throughput will facilitate mechanism investigation and drug screening. Altogether, the MSCA fellowship will allow me to work on a relevant project while building critical skills for continuing my career as an independent researcher.

Keywords: vascularization,3d in vitro models,human induced pluripotent stem cells
Impact of exposure to chemicals to the onset and progression of Lewy Body Dementia (FRANKIE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Czechia
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-04, 2022)
Start date: 2023-07-01
End date: 2025-06-30
Duration (months): 24.0
Total project cost (EUR): 150438.72
EU funding (EUR): 150438.72
Participants: 1
Project status: CLOSED

With aging, the incidence of neurodegenerative diseases is increasing. Clinical manifestations of neurodegenerative disease often result in dementia, a group of symptoms including loss of memory and impaired cognitive functions that have serious consequences for the wellbeing of aging individuals and society. Dementia is a syndrome of many diseases, including Lewy body dementia (LBD). Whilst the genetic factors contributing to the development of LBD have been investigated, links between exposure to chemicals and LBD have not been sufficiently studied. The FRANKIE project aims to comprehensively investigate the chemical exposome of patients with LBD and elucidate underlying mechanisms of exposure-related neurotoxicity. Blood-based chemical exposure agents and metabolites of LBD patients will be measured via a unique dual liquid chromatography coupled to high-resolution mass spectrometry platform. Advanced statistical and data mining methods will be employed to associate chemical exposures with dysregulated metabolic pathways to identify biomarkers of effect. Furthermore, by comparison of metabolic profiles of healthy people, people with early LBD and LBD patients, novel prodromal and clinical blood biomarkers will be identified. The proposed interdisciplinary, data-driven study is a big step towards understanding the influence of everyday chemical exposure on the onset and progression of neurodegenerative disease. The FRANKIE project will produce mechanistic insights of chemical exposure-related neurotoxicity, providing the opportunity to identify prevention measures and potentially reduce the incidence of neurodegenerative diseases to improve the quality of life of the elderly and aging populations and contribute towards a healthier society.

Keywords: exposome,exposure,dementia,biomarker,metabolite
Real-time biomarker detection systems for rapid medical decision-making in cancer and cardiac diseases (RealCare)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Unlocking the full potential of new tools, technologies and digital solutions for a healthy society
Action type: Innovation actions
Countries involved: Netherlands,Cyprus,Switzerland,Germany,France,Belgium,Romania
Call: Harnessing the potential of real-time data analysis and secure Point-of-Care computing for the benefit of person-centred health and care delivery (HORIZON-HLTH-2023-TOOL-05, 2023)
Start date: 2023-12-01
End date: 2028-11-30
Duration (months): 60.0
Total project cost (EUR): 8604850.5
EU funding (EUR): 8370156.75
Participants: 11
Project status: SIGNED

RealCare is a cutting-edge research initiative focused on developing and validating next-generation point-of-care (PoC) systems that detect essential biomarkers in human biofluids in real-time. These systems are designed to be compact, energy-efficient, and integrated with extended reality interfaces, with a specific emphasis on cancer and cardiac diseases in demanding clinical settings. RealCare's approach includes advanced biomarker detection technologies, such as microfluidics and new generations of microneedles, label-free electrochemical biosensors using 2D materials, optical sensors utilizing CRISPR, biological amplifiers combined with fluorescent microscopy, and scalable SPR with energy-efficient electronic readouts, AI data processing, and wireless communication units. Additionally, RealCare will design portable, interoperable, and adaptable PoC systems that integrate the biomarker detection technology with vital sign monitoring, including advanced data analytics and AI methods. The initiative also focuses on developing intuitive extended reality interfaces, such as augmented and virtual reality, to visualize biomarker data in real-time and facilitate rapid medical decision-making in integrated in-care environments and workflows. Rigorous clinical validation studies will be conducted in relevant clinical settings, including the surgery room, ICU, and patient's home, to ensure accuracy, reliability, usability, and impact on patient outcomes. RealCare places special attention on including a diverse patient population in their studies to validate the effectiveness of the developed systems. Data quality, interoperability, and medical data protection are key considerations in RealCare's strategy. Based on our unique PoC technological platform and our strong, multidisciplinary consortium partnership, we propose promising lab-to-market paths with the potential for significant societal impact.

Keywords: point of care system,real time monitoring of essential biomarkers,energy efficient,biosensing,lung cancer,cardiac diseases,clinical validation,ai data processing,intuitive extended reality
Hydrogen Production from Waste (HYWAY)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Luxembourg,China,Japan,Australia,Malaysia,Italy,United Kingdom
Call: MSCA Staff Exchanges 2022 (HORIZON-MSCA-2022-SE-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 387714.29
EU funding (EUR): 368000.0
Participants: 15
Project status: SIGNED

HyWay aims to synthesise hydrogen rich syngas from low cost carbon source, and eliminate the environmental issues from conventional waste management (e.g., landfill or incineration). HyWay advances the state-of-the-art in carbonaceous waste management especially plastic waste, waste tires, waste biomass and crude glycerol for hydrogen production. The overall aim of the HyWay is to establish long-term consolidated research collaborations between the participating institutions with complementary expertise and knowledge to design and develop carbon-neutral, scalable, and socially acceptable pathways to sort and convert waste to hydrogen-rich syngas as part of next generation sustainable fuels. Through secondments, workshops, training, webinar series, and industry-focused events, HyWay produces multiple avenues for career development, cross-sectoral experiences, and academic training in a multi-cultural and interdisciplinary environment. Research results are translated into training materials, including formal academic and industry courses on waste sorting, chemical recycling technologies, process modelling, machine learning, techno-economic analysis and life cycle analysis for postgraduate students, early-stage and experienced researchers and industry; training tutorials for industrial and technical staffs; and creating the basis for developing academic textbooks for the wider research community and possibly in undergraduate module delivery. There is also a focus on transferable skills, with dedicated training activities specially designed to facilitate personal development, technological and communication skills. HyWay delivers through the effective collaboration of 7 member state/associate country universities and companies, and eight third country universities and companies from China, Japan and Australia.

Keywords: hydrogen,pyrolysis,gasification,reforming,catalysis,waste,plastics,tires,crude glycerol,biomass,x ray ct,quartz crystal microbalance,digital twin,life cycle and techno economic assessment
ELIXIR-STEERS (ELIXIR-STEERS)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Belgium,Cyprus,Czechia,Estonia,Spain,Finland,France,Greece,Croatia,Hungary,Ireland,Israel,Italy,Luxembourg,Netherlands,Norway,Portugal,Sweden,Slovenia,Denmark,Switzerland,United Kingdom,Austria,Romania
Call: Consolidation of the RI landscape – Individual support for evolution and long-term sustainability of pan-European research infrastructures (HORIZON-INFRA-2023-DEV-01, 2023)
Start date: 2024-02-01
End date: 2027-01-31
Duration (months): 36.0
Total project cost (EUR): 4000000.01
EU funding (EUR): 3200000.0
Participants: 39
Project status: SIGNED

ELIXIR unites Europe’s leading life science organisations in managing and safeguarding the increasing volume of data being generated by publicly funded research. It coordinates, integrates and sustains bioinformatics resources across its 23 Nodes. ELIXIR enables users in academia and industry to access services (databases, software, training, standards, compute) provided through national Nodes. ELIXIR is the ESFRI Landmark for life science data and plays a unique role in the landscape, with millions of users globally, supporting the digital-needs of other ESFRIs and Horizon Europe research projects. Increasingly, life-science data is held at national and institutional centres. Thus, large-scale data analytics requires that researchers can find and analyse data distributed across Europe. The purpose of ELIXIR-STEERS is to build capacity for large-scale, cross-border data analysis and for this capacity to be embedded across member states. ELIXIR-STEERS directly benefit Europe’s life scientists by allowing software and workflows to meet requirements of those using them in national centres. A ‘robust, reproducible and green’ approach to software and workflow provision will ensure that scientists have access to high quality, energy-efficient analysis tools. The project will also develop the crediting and recognition systems for software, supporting improvements to research assessment frameworks. Further, ELIXIR-STEERS supports ELIXIR’s long-term operations by addressing the recommendations of the European Commission and ESFRI on the long-term sustainability of research infrastructures. It will strengthen the operational excellence of ELIXIR’s Nodes; support the training and development of professional and scientific staff in ELIXIR Nodes; expand the membership of ELIXIR to new countries, especially widening countries; enable international collaborations in particular with Latin America and Africa; and stimulate innovation and industry engagement.

Keywords: sustainability,impact,innovation,software,workflows,coordination,user support,european research area,training,capacity building,open science,partnerships,membership expansion
Sociology of Authoritarian Law: Insights from Central Asia (SOCIAL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Sweden,United Kingdom,Türkiye,Estonia,Germany,Uzbekistan,Tajikistan,Turkmenistan,Kyrgyzstan,Kazakhstan,Japan,Canada,Latvia,Czechia,Lithuania,Switzerland,Netherlands
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 4579286.4
EU funding (EUR): 4579286.4
Participants: 34
Project status: SIGNED

The overarching objective of the SOCIAL is to contribute to global and national efforts in understanding and addressing the challenges associated with promoting democratization and good governance in authoritarian contexts. More specifically, SOCIAL is built around three interconnected goals: 1. To collect original empirical data and produce new theoretical and empirical insights on the interplay between law, society and governance in authoritarian regimes in the Central Asian context. The empirical findings will enable us to engage with and advance theoretical debates within (comparative) political regimes literature and authoritarian law/legality scholarship. 2. To create, develop and enhance the sustainability of doctoral training programmes focused on the study of authoritarian regimes. Our proposed programme will involve a variety of disciplines, sectors, fields and geographical regions. By doing this, we will equip doctoral candidates with a comprehensive understanding of the interplay between law, society, and governance in authoritarian regimes, which will be embedded in the novel theoretical and methodological approaches. 3. To engage with and contribute to the global democratization and good governance agenda by translating research findings into policy-relevant ways and providing strategic intelligence and policy insights for international organisations, development agencies, decision-makers, researchers and practitioners inside and outside the EU on ways to promote democratization and good governance in authoritarian contexts. These goals will be accomplished by designing and conducting interdisciplinary and multisectoral doctoral networks programme on the “sociology of authoritarian law” involving 17 doctoral candidates, each completing a PhD at one of the 14 leading universities in Europe and Canada that are part of the SOCIAL consortium.

Keywords: sociology of authoritarian law law and society central asian studies authoritarian law and legality hybrid legal regimes