Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Transformation of existing urban district heating and cooling systems from fossil to renewable energy sources (RES-DHC)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Coordination and support actions
Countries involved: Austria,Italy,Italy,Austria,Germany,Italy,Germany,Germany,Switzerland,Poland,Belgium,Switzerland,France,France,Denmark
Call: Market Uptake support (H2020-LC-SC3-2020-RES-IA-CSA, 2020)
Start date: 2020-09-01
End date: 2023-08-31
Duration (months): 36.0
Total project cost (EUR): 2582946.25
EU funding (EUR): 2582946.25
Participants: 17
Project status: SIGNED

RES-DHC stands for a wider introduction of Renewable Energy Sources (RES) in the District Heating and Cooling (DHC) sector. The RES-DHC project addresses the manifold market uptake challenges related to the transformation of DHC systems to higher shares of RES. In particular it aims at the development of solutions and instruments which support policy and sector stakeholders in (over-)fulfilling Art. 24 of the Renewable Energy Directive II (directive 2018/2001), requiring a yearly increase of RES in DHC by 1%. The main objective of the RES-DHC project is to support the transformation of existing urban DHC systems to RES in six participating regions and thereby to derive - from these practical cases - technical and organizational solutions for such transformation processes. This is reached with two key approaches: A vertical pillar of the project is a close-to-market implementation process of concrete actions and measures by regional stakeholder consortia in the six regions (in DE, AT, IT, PL, FR and CH). The phases of this implementation process are 1) strategy and action planning based on local stakeholder consultation 2) an implementation phase starting already at an early stage of the project including capacity building, legal framework improvements, market support, and triggering investments in RES DHC. Technical enablers are, beside RES, also sector coupling and the use of low grade heat sources. A key horizontal beam of the project is to organize and give transnational support to the regional stakeholder consortia. This support is provided by an international team of expert partners with specific and complementary competences and coordinated by Danish experts. The specific actions of the RES-DHC project meet the market uptake challenges of this call to a great extent, e.g.: Introduction of RES at large scale, stakeholder engagement, assessment of legal and political frameworks and of the environmental, economic and social impact of RES DHC solutions.

Keywords: renewable energy sources,district heating and cooling,energy transition,sector coupling,market uptake,capacity building,business models,financing,region,investor,consumer,policy,secap
Technology Diffusion Model (TeDiMo)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Germany
Call: TE Technology diffusion model (H2020-CS2-CFP07-2017-02, 2017)
Start date: 2018-12-03
End date: 2020-12-02
Duration (months): 24.0
Total project cost (EUR): 199413.75
EU funding (EUR): 199413.75
Participants: 1
Project status: CLOSED

The composition of a future aircraft fleet is, among others, dependent on new available technologies contributing to improved aircraft eco-efficiency. Thus, it is essential to know whether and to which extent new technologies find their way on the aircraft (either as a new configuration or as retrofit). The main objective of the project TeDiMo (“Technology Diffusion Model”) therefore is to establish a sophisticated technology diffusion model in the context of the Technology Evaluator (TE) that facilitates the investigation of the propagation of new technologies developed in Clean Sky 2. By applying the diffusion model to CS2-technology bricks a more comprehensive response of the contribution of the developed CS2-technologies towards the Flightpath 2050 goals is obtained. At this stage, technologies are assessed in specific concept vehicles which, however, do not cover the whole range of aircraft categories of the operated world fleet. Hence, for the categories not populated with CS2 concept vehicles additional representative aircraft have to be defined. Ecological, economic and social drivers that have a significant influence on the air transportation system must be then identified in order to derive changing requirements and the motivation for developing and installing new technologies into air vehicles. Applying the diffusion model by taking both current technological requirements and the motivation into consideration helps to understand the time-dependent propagation steps of new technologies (within and across the particular aircraft categories) and therefore to assess future aircraft fleet compositions. The project outcome comprises the prediction of future aircraft fleet due to the implementation of new technologies including the demonstration of technological diffusion models in the aviation sector.

Keywords: technology assessment,technology impact,technology diffusion,diffusion model,aircraft fleet composition
An-Iconology: History, Theory, and Practices of Environmental Images (AN-ICON)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Italy
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-09-01
End date: 2025-02-28
Duration (months): 66.0
Total project cost (EUR): 2328736.0
EU funding (EUR): 2328736.0
Participants: 1
Project status: SIGNED

Recent developments in image-making techniques have resulted in a drastic blurring of the threshold between the world of the image and the real world. Immersive and interactive virtual environments have enabled the production of pictures that elicit in the perceiver a strong feeling of being incorporated in a quasi-real world. In doing so such pictures conceal their mediateness (their being based on a material support), their referentiality (their pointing to an extra-iconic dimension), and their separateness (normally assured by framing devices), paradoxically challenging their status as images, as icons: they are veritable “an-icons”. This kind of pictures undermines the mainstream paradigm of Western image theories, shared by major models such as the doctrine of mimesis, the phenomenological account of image-consciousness, the analytic theories of depiction, the semiotic and iconological methods. These approaches miss the key counter-properties regarding an-icons as "environmental" images: their immediateness, unframedness, and presentness. Subjects relating to an-icons are no longer visual observers of images; they are experiencers living in a quasi-real environment that allows multisensory affordances and embodied agencies. AN-ICON aims to develop “an-iconology” as a new methodological approach able to address this challenging iconoscape. Such an approach needs to be articulated in a transdisciplinary and transmedial way: 1) HISTORY – a media-archaeological reconstruction will provide a taxonomy of the manifold an-iconic strategies (e.g. illusionistic painting, pre-cinematic dispositifs, 3D films, video games, head mounted displays); 2) THEORY – an experiential account (drawing on phenomenology, visual culture and media studies) will identify the an-iconic key concepts; 3) PRACTICES – a socio-cultural section will explore the multifaceted impact of an-iconic images, environments and technologies on contemporary professional domains as well as on everyday life.

Keywords: image theory,visual culture studies,media archaeology,phenomenology,technoaesthetics,immediateness,unframedness,presentness,illusion,transparency,immersivity,interactivity,participation,embodiment,avatar,multisensoriality,hyper realism
Future Toxicology: Better predicting Toxicant-induced cell fate. (TOXIFATE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain,Ireland
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2020-10-01
End date: 2024-09-30
Duration (months): 48.0
Total project cost (EUR): 525589.2
EU funding (EUR): 525589.2
Participants: 2
Project status: SIGNED

TOXIFATE will help change the paradigm of chemical safety assessment and give the next generation of toxicologists the fundamental knowledge and experimental skills that are required to bring about this change. The safe use of chemicals is essential for global prosperity and human health and this is entirely dependent upon robust toxicology. For practical, scientific and ethical reasons, modern toxicology is moving to computational approaches in which large datasets describing chemical structures and toxicological outcomes are used to predict toxicity. The promise of this approach was recently demonstrated when computational approaches for the first-time outperformed animal testing in predicting human toxicity. Nonetheless, our ability to predict toxicity is poor because our understanding of how chemicals affect cells is still rudimentary. TOXIFATE will provide intersectoral training to 2 researchers who will build new assays to detect toxicant-induced changes in cells. Multi-disciplinary training will generate unique high-content and transcriptomic data describing cell stress and cell death responses. This multidimensional dataset will be used to develop novel computational approaches to improve toxicity prediction. TOXIFATE will focus on chemical-induced myotoxicity, a severe and sometimes life-threatening toxicity that is characterized by skeletal muscle breakdown. Although at least 200 drugs and chemicals cause myotoxicity, it is relatively under-investigated and what is learnt here to improve prediction of myotoxicity will also be used to improve prediction of other types of toxicity. TOXIFATE researchers will bridge the gap between state-of-the-art science and chemical hazard and risk assessment and be equipped for career paths in the emerging computational toxicology sectors. TOXIFATE will also aid the EU and the global community by quickly, ethically and economically addressing the societal challenge of better identifying chemical hazards to human health.

Keywords: cell stress,cell death,cell differentiation,myotoxicity,muscle toxicity
Feasibility study for registration of medicine RIGVIR with the European Medicine Agency (RIGVIR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Biotechnology
Action type: SME instrument
Countries involved: Latvia
Call: Dedicated support to biotechnology SMEs closing the gap from lab to market (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-08-01
End date: 2017-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Cancer is one of the most dangerous life-threatening disorders for humanity of which melanoma is considered to be one of the most dangerous and aggressive. There are a number of therapies available to treat melanoma. However, these treatments are generally marginally effective and very expensive. Latima SIA develops and produces Rigvir® for virotherapy. Rigvir® is a unique anti-cancer medicine using non-pathogenic virus. It has been demonstrated to be very effective in treating various cancers, and has a promising medical future . RIGVIR is commercialised in Latvia, Georgia and Armenia. Rigvir® was approved and registered in Latvia in 2004 and has since been a front-line treatment for melanoma in Latvia. However,further use and commercialisation in the EU is prevented as EU regulations require cancer medicines to be registered centrally through the European Medicine Agency (EMA). National registrations are not considered. Therefore, the process for European Union registration must be started de novo. Registration of a medicinal product requires significant costs and resources. The purpose of this H2020-SMEInst-2016-2017 application is to secure the financial support for an initial feasibility study that would provide the basis for subsequent clinical trials necessary for the registration of Rigvir® with the EMA. It is expected that after feasibility study we would continue with next phase of H2020-SMEInst-2016-2017 and perform the clinical trials necessary for registration in EMA.

Keywords: research of registration requirements at ema,development of protocols for cynical trials,selection of,partners for registration and clinical trials
Physical Activity and Nutrition INfluences In ageing (PANINI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy,Italy,Italy,Finland,Finland,Netherlands,Netherlands,Netherlands,Netherlands,United Kingdom,Portugal,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2015, 2015)
Start date: 2016-01-01
End date: 2019-12-31
Duration (months): 48.0
Total project cost (EUR): 2865980.32
EU funding (EUR): 2865980.3200000003
Participants: 17
Project status: CLOSED

Life expectancy is increasing dramatically, but the period of good health (healthspan) enjoyed by most is not keeping pace, with implications for health, social care, and pensions resulting in estimated costs more than doubling by 2050. Thus, understanding the many factors that contribute to healthy ageing versus frailty, and validating interventions and influencing policy to promote healthy ageing is a cross-cutting research priority in Europe. Given the considerable impact of lifestyle factors on healthy ageing and disease, there is a surprising lack of innovative multi-disciplinary training and research examining the influence of physical activity and nutrition on age-related changes at gene to societal level. PANINI will address this gap by coordinating research laboratories across Europe to focus on cutting-edge ageing and health research through training 11 ESRs across scientific disciplines to create a holistic approach to the challenge of ageing in the 21st Century. PANINI is a European Training Network with 8 world-leading beneficiaries working on Healthy Ageing and 10 non-academic partners carefully selected for quality and range of sectors. These vary in size including 1 large nutrition company, 5 SMEs, 2 charities, 1 healthcare partnership and 1 EU Joint Research Centre. PANINI’s vision is to implement multidisciplinary cross-sectoral research and training of a new cohort of researchers taking a radically innovative approach to overcome the challenge of unhealthy ageing. The main goals of PANINI are to: integrate expertise from basic biomedical science and technology to applied clinical practice; standardise measurements across the network to create a toolkit and shared dataset; provide multidisciplinary training secondments to expose ESRs to healthcare and industry research settings and other laboratories; disseminate widely the shared and individual project findings; and use these to develop a policy document to promote healthy ageing in Europe.

Keywords: physical activity,nutrition
Copernicus for environmental law enforcement support (EnviroLENS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Innovation actions
Countries involved: Austria,Austria,Greece,Switzerland,Slovenia
Call: Copernicus market uptake (H2020-SPACE-2018, 2018)
Start date: 2018-12-01
End date: 2021-05-31
Duration (months): 30.0
Total project cost (EUR): 2523918.75
EU funding (EUR): 1998923.0
Participants: 6
Project status: CLOSED

The proposed project: “Copernicus for environmental law enforcement support” (hereafter: EnviroLENS) aims to widely open the doors towards regular usage of EO technologies in legal sector. The goal of EnviroLENS is to deliver specific environmental governance and enforcement services that will enable immediate and EFFECTIVE environmental MONITORING and ENFORCEMENT → providing legal precedents thus, establishing a confidence base amongst user community → providing a motivation for policy/contract designers to construct statutory/legal solutions that clearly foresee the usage of EO data/services → boosting the employment of EO services in legal sector. EnviroLENS delivers three types of innovations: 1. TECHNOLOGICAL INNOVATIONS Earth observation technology + Semantic data mining technology will be used to merge two seemingly unrelated domains (EO and legal domain) into a joint environmental enforcement eco-system. 2. CONCEPTUAL INNOVATIONS; EnviroLENS is delivering a cross-domain solution = not constrained by usage domain nor constrained by the type of EO service. The uniqueness of the EnviroLENS arises from its front-office capabilities; EnviroLENS can embrace any EO service and transform it by enriching it with new (LEGAL) added value. 3. COMMERCIAL INNOVATIONS are based on EnviroLENS open value chain strategy, the main idea being that anybody can contribute and receive commercial benefit out of his contribution. The project is dedicated into the promotion of EO data as admissible court evidence, not just to change the ruling procedures, but to provide tenets for policy makers and lawyers to seriously consider usage of EO data as regular means of environmental control (making it part of regulations: laws and contracts). EnviroLENS will create completely new market niche addressing LEGAL domain in areas of: Contractual management and Environmental governance. Project exibits high market potential with 30.000.000 EUR NPV and 35% IRR.

Keywords: domain fusion,legal domain
Utilizing diversity to decipher the role of autophagy in plant-microbe interactions (DIVERSIPHAGY)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Germany,Germany
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-03-01
End date: 2026-02-28
Duration (months): 60.0
Total project cost (EUR): 1499462.0
EU funding (EUR): 1070774.5
Participants: 2
Project status: SIGNED

During the course of evolution, plants have been exposed to a plethora of beneficial and pathogenic microbes. While symbionts are beneficial for the host plant by improving nutrient supply and health, pathogens are reprogramming their host only for their own benefit. At the interface of this interaction proteomes at both sides are highly flexible and require regulated protein turnover. In line with this, our previous work revealed that regulated protein degradation by autophagy is an essential player in plant immunity. Consequently, plant pathogens hijack autophagy during binary interactions though in contrasting manners. However, in a more complete scenario, plants are constantly exposed to different microbes and hence it is crucial to include the microbial diversity into this equation to obtain a holistic picture of the role of autophagy in plant-microbe interactions. The picture is getting even more complex if we look at the cellular diversity on the host side. Thus, DIVERSIPHAGY approaches the role of autophagy through bacterial and cellular diversity on the host side. We aim to address following questions: • Identifying how the bacterial diversity impacts autophagy and vice versa • Determining new bacteria and/or bacterial communities hijacking autophagy • Revealing the autophagy degradome and novel autophagy factors by utilizing autophagy-modulating bacteria • Identifying tissue and cell-type specific modulation of autophagy by diverse bacteria. With DIVERSIPHAGY we will reveal the holistic picture of the role of autophagy in plant-microbe interactions using a mixture of state-of-the-art approaches including metabolomics, proteomics, single-cell transcriptomics and cell-type specific reverse genetic screens. As such DIVERSIPHAGY is the next generation approach to understand the role of plant autophagy in plant-microbe interactions and by translating our results into crop plants we will be able to develop more durable resistances toward destructive pathogens.

Keywords: autophagy,plant microbe interactions,plant immunity,microbiome,effectors
Low-powered microwave quantum-enhanced communication: conceptualisation and preliminary design (Green-MIQUEC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Finland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-03-01
End date: 2022-02-28
Duration (months): 24.0
Total project cost (EUR): 190680.96
EU funding (EUR): 190680.96
Participants: 1
Project status: CLOSED

This proposal is a contribution of quantum technologies to the communications engineering field, with a potentially high societal impact. Its aim is to theoretical study low-powered microwave quantum communication protocols in realistic scenarios, via developing a quantum-enhanced version of Ambient Backscatter Communication (AmBC). This is a high-innovative paradigm that makes use of signals already present in the environment - e.g. generated by a TV-tower - in order to implement low-powered communication between devices, with applications in healthcare and wireless communication. The quantum-enhanced version will gain largely in energy-efficiency with respect to the current quantum BC and quantum radar designs, keeping the same quantum advantage. The proposal will approach the problem at different levels of knowledge: from the fundamental level to the final engineering design. I will build a rigorous framework based on resource theory for how to use open-air quantum microwaves to perform a quantum-enhanced backscatter communication in a very lossy scenario. This will be used to introduce a novel microwave quantum illumination protocol based on Schrödinger's cat states instead of Gaussian states. My approach will need only passive devices and no photodetection, solving major issues for a microwave implementation and allowing to extend the paradigm to the low-powered AmBC case. This is a multidisciplinary project, touching aspects of quantum information, low-temperature physics and communications engineering, for which there will be a double transfer-of-knowledge with the Aalto staff members. The research training will be complemented by a set of transferable skills including Self- and Team-Leadership, Pedagogy, Communication, which will make me more employable both inside and outside academia. The host has been chosen as the only EU place with both experts in AmBC and superconducting circuits in the staff.

Keywords: quantum metrology,quantum illumination,quantum communication,quantum microwaves,superconducting circuits,quantum information,ambient backscatter communication