Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Innovative and ultra-low power neuromorphic unit for advanced signal processing in wearable medical devices (DynapIP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Nowadays, ~220M of the worldwide population of which over 50M only in EU, currently live with more than one chronic condition. Early and accurate detection of adverse events are fundamental for proper clinical management. To meet this need, the healthcare system is becoming increasingly personalized with the help of self-health monitoring systems and in particular medical wearable devices. However, constant monitoring generates large amounts of raw data which must be stored and processed to extract pathological biomarkers. Normally, this is done using microprocessors commonly found in computers as central processing units (CPUs) or graphic processing units (GPUs), or on specialized microprocessors such as digital signal processors (DSPs) that have some limitations as implying high power consumption (>100W) and no real time signal processing. aiCTX offers DynapIP, a neuromorphic chip with extremely long battery life (3 months) and low-power consumption (<100uW) able to perform sophisticated signal processing and react to sensory input in real-time enabling continuous monitoring and real time analysis of biological signals captured by wearable medical devices. The hardware can be fully customized based on client needs and these approaches can be applied to a wide variety of biosensors, such as ECG, EOG, EMG and EEG. Wearable devices using DynapIP automatically identify in real-time (less than 100ms) pathological events with high accuracy facilitating faster and immediate diagnosis for healthcare personnel. During the feasibility assessment, a go-to-market strategy will be established, as well as further development plan will be drafted. During the innovation project, aiCTX will optimize the existing neuron/synapses hardware modules for different biosensors and the software integration to support the new hardware modules of the DynapIP. Pilot study for validation of biosignal analysis and functionality of the technology will be conducted together with secured partners

Keywords: neuromorphic,real time computing,ultra low power,physiological signals processing,medical wearable devices
Search for an experimental test of the mean-field theory of simple glasses (EXPMFSG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-07-16
End date: 2017-11-04
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

The goal of this project is to contribute to the design and execution of a precise experimental test of a theory for the glass and jamming transitions. Indeed, the last few years have witnessed a considerable advance in the microscopic description of glassy systems: an intrinsic relation between these two transitions has been uncovered. The phase diagram was obtained, finding that the jamming transition is located inside the glass phase and corresponds to a transition from entropic rigidity to mechanical rigidity. This last year has brought new breakthroughs: the jamming critical exponents can be computed with the theory, which suggests a precise test in a lab. The testing of these new progresses in theory requires an integrated research program joining theory and experiment, an opportunity that is emerging in Paris, by the collaboration of the group of F. Zamponi (supervisor of this action and one of the co-authors of the main last theoretical results) with the nearby experimental group leaded by O. Dauchot. Hereby, I present this project with the aim of being part of this exciting opportunity.

Keywords: glass transition,jamming transition
Social Systems in Transition: The Meaning of Collective Identity and the Interpretation and Translation of the Greek Term Sarx in Paul’s Letters (MaSarx)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-08-17
End date: 2022-12-30
Duration (months): 24.0
Total project cost (EUR): 214158.72
EU funding (EUR): 214158.72
Participants: 1
Project status: CLOSED

The aim of the project is to explore community differentiation implications arising from the Greek term sarx in Paul’s letters. The choice of primary material is based on the observation that this term recurs in settings where collective identity is established, and where the salvific capacity of collective identity is polemically engaged and negotiated (see Rom 7–9; Gal 5). The earliest group of Christ-believers gathered together in social systems which were in transition toward a higher level of diversity, which is an underinvestigated aspect of these texts. The primary objective is to investigate Paul’s views of differentiation and the constructs of collective identity in the settings where he uses the term sarx, and to consider the options for the translation of the relevant passages. Hence, the approach of the action is interdisciplinary (social-scientific criticism in Biblical studies) and intersectoral (the theory and practices of translation). Bowen’s social systems theory offers the terminology to describe the character, reactions, and development in social systems with regard to their level of differentiation and their capacity to handle psychological stress and to find solutions to new problems. The action comprises theological, linguistic and philological analysis, comparative literature, social-scientific hermeneutics, and the creative investigation of translation options. As described in social systems theory, an openness to individual variation in the social system is central to the development of societal resilience. In this context, religious communities act both as significant resources, as well as potential threats, to cooperation in diversity. The investigation of translation options will make the results of the action accessible to anyone interested in these texts, in their interpretation, and in social systems in transition.

Keywords: new testament studies,psychological hermeneutics,biblical studies,pauline studies,translation,family systems theory
Corrector equations and random operators (COR-RAND)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Belgium,France
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-09-01
End date: 2025-08-31
Duration (months): 60.0
Total project cost (EUR): 1540000.0
EU funding (EUR): 1207500.0
Participants: 2
Project status: SIGNED

Consider a partial differential equation (PDE) with random coefficients as in engineering or applied physics: When combined with a spatial scale separation, the randomness and the differential operator interact to give rise to some effective behavior. The recent growing mathematical activity in this domain has led to a ``seemingly'' complete theory of stochastic homogenization of linear elliptic operators. Central to this theory is the so-called corrector equation, a degenerate elliptic equation posed on the (infinite-dimensional) probability space. The context of linear elliptic operators yields the simplest such equation. Time-dependent and/or nonlinear PDEs also involve corrector equations (or a family thereof), albeit with a significantly more complex structure. Their study and use to characterize the large-scale/time behavior of solutions of PDEs with random coefficients are at the heart of this project. Whereas the relevance of corrector equations is clear in problems such as diffusion in random media, sedimentation of randomly placed particles in a fluid, or water waves on a rough bottom, it is less obvious for the long-time behavior of waves in disordered media. The latter is related to the spectrum of the associated random elliptic operator, the characterization of which still remains a largely open question today. We propose to relate the long-time behavior of waves to the properties of a family of corrector equations. These corrector equations are widely unstudied and offer many analytical challenges. They constitute the first half of the project. Even in the ``well-understood'' setting of linear elliptic operators, this requires to revisit the corrector equation in the light of much weaker topologies than considered before. The second half of the project aims at using correctors to establish the large-scale behavior of solutions as random objects. This may involve surprising quantities such as the recently introduced ``homogenization commutator".

Keywords: pdes with random coefficients,homogenization,effective behavior,fluctuations,waves
European Hydrogen Train the Trainer Programme for Responders (HyResponder)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Coordination and support actions
Partnership: FCH2 (Art-187)
Countries involved: Italy,Austria,Spain,Germany,Norway,Belgium,Switzerland,France,France,France,Czechia,United Kingdom,United Kingdom
Call: Training of Responders (H2020-JTI-FCH-2019-1, 2019)
Start date: 2020-01-01
End date: 2023-05-31
Duration (months): 41.0
Total project cost (EUR): 1000000.0
EU funding (EUR): 1000000.0
Participants: 17
Project status: SIGNED

The aim of the HyResponder project is to develop and implement a sustainable trainer the trainer programme in hydrogen safety for responders throughout Europe, supporting the commercialisation of hydrogen and fuel cell technologies by informing responders involved in the permitting process, improving resilience and preparedness, and ensuring appropriate accident management and recovery. The specific objectives of the project include the development of clear and updated operational, virtual reality, and educational training for trainers of responders to reflect the state-of-the-art in hydrogen safety. The European Emergency Response Guide for responders will be revised to reflect advancements. The materials will incorporate identified intervention strategies and tactics for liquefied hydrogen applications. A Pan-European Network of responder trainers will be established and trainers from at least 10 European countries will attend a bespoke course in hydrogen safety pertinent to responders. Using feedback from the network on national specificities, educational training materials will be adapted where required to reflect regional peculiarities. The materials for responders will be translated and made available in 8 languages via an e-Platform. The translated materials will be utilised by the newly trained trainers to deliver workshops in 10 countries across Europe enhancing the reach and impact of the programme. National Training Clusters will be developed to consolidate links between the hydrogen safety and responder communities and to support the delivery of workshops at a national level. Through the establishment of an International e-forum for responders, and the integration of the translated materials in the e-Platform, it is anticipated that a sustainable pan-European training programme in hydrogen safety for responders will be developed, which will be recognised as the standard in hydrogen safety training across Europe.

Keywords: responders,hydrogen safety,european network,train the trainer,operational training,european emergency response guide,virtual reality
SEIMED services to enhance innovation management capacity of SME's KAM services (SEIMED INNOSUP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Spain,Spain,Spain
Call: Enhancing the innovation management capacity of SMEs (H2020-Adhoc-2014-20, 2014)
Start date: 2015-01-01
End date: 2016-12-31
Duration (months): 24.0
Total project cost (EUR): 230322.5
EU funding (EUR): 230322.5
Participants: 10
Project status: CLOSED

Innovation support by the Enterprise Europe Network - SEIMED to enhance the innovation management capacity of SMEs & services as key account managers for the SME Instrument beneficiaries in the regions of Comunidad Valenciana y Murcia. In order to enhance SME innovation management capacity, we will support SME´s to implement truly effective processes in order to become more competitive and have a pro-active attitude towards the changing business environment. The traditional approach to innovation is insufficient to make a qualitative leap in competitiveness and facilitate the renewal of the company. Our purpose within this programme is to accompany the enterprise in the process of diagnostic audit, definition of an action plan and the implementation of an innovation management system. It is necessary to create a system that could continuously generate innovation and not only erratic and sporadic progress. This service will be implemented as comprehensive seven-day service packages following the processes and guidelines that are laid down for this purpose. It will be delivered by suitably qualified senior innovation experts and be linked to the other support services of the Enterprise Europe Network SEIMED.

Keywords: sme instrument,coach,innovation assessment,gaps,choaching plan,diagnostic audit,innovation management system,imp3rove,innovation strategy,culture and creativity
Low Coordinate Transition Metal Single Molecule Magnets (LoCo)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-02-13
End date: 2019-08-27
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

The Fellow, Maialen Espinal (MEV) from the University of Bath, outlines a case for support to work alongside the Host, Prof Mike Whittlesey (MKW: University of Bath, UK), on the design of novel two-coordinate complexes of Ni, Co and Fe as single molecule magnets (SMMs).The rationale for the work is the 2013 report by the MKWs group of a cationic Ni(I) N-heterocyclic carbene complex that exhibited the first example of SMM behavior observed in a mononuclear Ni complex. SMMs are the focus of considerable multidisciplinary investigations because of their potential for high-density information storage and quantum computing. Most work until now has focussed on lanthanides, but there has been an increasing realisation that organotransition metal derived SMMs may offer significant benefits in terms of their ability to stabilise different electronic environments as a result of being able to adopt unique coordination geometries. MEVs approach will be to use large ring NHC ligands and probe the influence of ring size, substituents, coordination mode and resulting molecular geometry on magnetic behaviour. The project will utilise the research experience of the applicant in synthetic chemistry to make new compounds in Bath, but most importantly, provide her a unique opportunity to develop new skills for progression of her career by exposure to new techniques and methodologies through periods of secondment to internationally leading laboratories for studies of magnetism (Prof Annie Powell (AKP), Karlsruhe, Germany), paramagnetism via Electron Paramagnetic Resonance (Prof Damien Murphy (DMM), Cardiff, UK) and computational chemistry (Prof Stuart Macgregor (SAM), Heriot-Watt, UK).

Keywords: single molecule magnets,magnetism,transition metals,low coordinate complexes,carbenes
ONCOgenic Receptor Network of Excellence and Training 2.0 (ONCORNET2.0)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Spain,Germany,Switzerland,France,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2019, 2019)
Start date: 2020-02-01
End date: 2024-01-31
Duration (months): 48.0
Total project cost (EUR): 4099781.52
EU funding (EUR): 4099781.5199999996
Participants: 10
Project status: SIGNED

Cancer is a major health burden responsible for 20% of European deaths. There is a critical need to understand its fundamental biological mechanisms. G protein-coupled receptors (GPCRs) are cell surface proteins which play an important role in regulating cellular functions integral to cancer biology and, as highly druggable proteins, oncogenic GPCRs are important therapeutic targets. ONCORNET2.0 builds on the success of ONCORNET (Oncogenic GPCR Network of Excellence and Training), a first-in-kind ETN in GPCR drug discovery that has successfully delivered scientific advance and training to talented early stage researchers (ESRs). ONCORNET2.0 will incorporate recent scientific and technological advances to understand and target two oncogenic GPCRs; the chemokine receptors CXCR4 and ACKR3. These are highly expressed in multiple tumours but their role in cancer progression remains poorly understood. We will develop new strategies for CXCR4/ACKR3 modulation (photochemistry, nanobodies) and investigate their effects on oncogenic responses, to yield key new knowledge and potential leads for drug development and commercialisation. ONCORNET2.0 will bring together the leading GPCR research groups in Europe and 15 ESRs. By leveraging on the success and experience of ONCORNET and recent ground-breaking advances in the field of GPCRs (e.g. cryo-EM, CRISPR-Cas, advanced microscopy), ONCORNET2.0 brings a young, gender-balanced team of PIs to target oncogenic GPCRs. The consortium will offer an extensive multidisciplinary training programme for ESRs ensuring their successful incorporation in today’s fast-moving drug development programmes. This programme integrates both research and transferable skill sets through blended learning. Our aim is that, through training these ESRs with interdisciplinary and intersectoral exposure, we will develop the next generation of scientists with skills that are in high demand by the drug development industries but rarely offered academically.

Keywords: g protein coupled receptor,chemokine,oncogenesis,beta arrestin,drug discovery
Radically innovative bacterial treatment for recalcitrant industrial wastewater (RIBATI)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2019)
Start date: 2020-05-01
End date: 2022-04-30
Duration (months): 24.0
Total project cost (EUR): 1025505.71
EU funding (EUR): 717854.0
Participants: 1
Project status: CLOSED

Manufacturing industries are responsible for large loads of contaminants discharged in water. As each wastewater has different composition, each of them requires specific treatment in order to remove the contaminants. Treatments are expensive (€40-121,4/m3) and usually their efficiency is low – as little as 20% in some sectors. Moreover, EU environmental regulations are becoming stricter. These facts are putting the industry at serious risk: factories may be forced to closure because of the high costs and the non-compliance with regulations, which involves heavy sanctions. Amapex has developed RIBATI, an integral industrial wastewater treatment service based on 3 key elements: i) Active Product, composed by a blend of a specific registered bacterial strain and a selected variety of 12 oligoelements; ii) Smart Doser Unit, an exclusive automatic device that adjusts dose, time, temperature and life cycle of the active product, and iii) an integral service including a landing study, installation, maintenance, supply of active product and recurrent analysis of treated wastewaters. Our invention has been tested with more than 30 potential clients with promising results: leading up to 59% savings and allowing for water reuse in some water-intensive industries like the textile sector. Our solution is adapted to the industry’s needs and it also adapts to the needs of every individual client. Our revenue model will be based on subscriptions, what we call RIBATI PAY PER FLOW. Our target are SMEs from the textile, tanning, metals processing, chemical and car wash sectors, which represent 30% of the EU manufacturing sector (around € 1,85 bn in Europe). Our target countries are Spain, Italy, France, Belgium, Netherlands and Germany. By year 5, we expect to treat about 500.000 m3 of wastewater and to generate around €12,3M revenues, an EBITDA of €8,3M, an IRR of 80% and an NPV of €7M (discount rate of 15%). We also expect to create 15 new jobs.

Keywords: biological treatment,industrial wastewater,energy efficiency,environment,water consumption,contaminants,chemical oxygen demand