Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Assessing early social complexity in the Late Prehistory of Southern Iberia: Spatial technologies applied to the study of chalcolithic walled and ditched enclosures. (IBERENCLOGIS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-09-01
End date: 2015-08-31
Duration (months): 24.0
Total project cost (EUR): 221606.4
EU funding (EUR): 221606.4
Participants: 1
Project status: CLOSED

Some of the most impressive prehistoric archaeological sites in the European continent, some exceeding 100ha in size, have been discovered in recent decades in southern Iberia. Referred to as 'ditched enclosures', these date to the Chalcolithic/Copper Age (4th-3rd millennia BC) and generally consist of a sub-circular or oval flat area, usually surrounded by a series of ditches. Partially contemporary with Iberian ditched sites are 'walled enclosures', smaller areas surrounded by one or more lines of stone based walls with adjacent 'bastions' and 'towers'. Most Iberian archaeologists have considered walled and ditched enclosures as the earliest evidence for fortified, permanently occupied settlements, inhabited by sedentary farming communities. Additionally, Iberian chalcolithic enclosures are the empirical basis of hypotheses which defend that southern Iberia saw the emergence of the earliest 'state societies' in prehistoric Europe during the III millennium BC. In the last ten years, however, by questioning whether walled and ditched enclosures were indeed 'fortified settlements', several authors have challenged these claims, making this one of the most controversial topics in the archaeology of Iberia and of profound relevance to the whole continent. The proposed project, with a duration of 24 months, will make use of spatial approaches and GIS to analyse Iberian walled and ditched enclosures and compare them with contemporary European sites. This will give us a clearer idea of the nature of Iberian enclosures, as well as the social processes responsible for the construction of such monumental structures, shedding some light on the beginnings of social complexity in Western Europe. In order to achieve the project's objectives, the fellow will first complete postgraduate taught modules in Archaeological GIS and Social Archaeology at the University of Southampton.

Keywords: s101 social structure - inequalities - social mobility,s401 archaeology - archaeometry - landscape archaeology,s402 prehistory and protohistory,v104 geographical information systems - cartography
The roots of plant productivity: how the rhizosphere interact with the aboveground armament for indirect and direct defense against abiotic stressors (ROOTS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-04-01
End date: 2015-03-31
Duration (months): 24.0
Total project cost (EUR): 187414.8
EU funding (EUR): 187414.8
Participants: 1
Project status: CLOSED

The roots represent at least half, by mass, of the body of a plant; through this hidden part, water and nutrients are assimilated, and together with atmospheric CO2, constitute the basis of the entire reserve food of the planet. Moreover, the roots affect plant growth through many other processes in addition to their role in water and nutrients uptake: located at the interface between soil and above-ground part, the root system plays a crucial role in anchoring and reacting to biotic and abiotic stresses. Furthermore, stress events at the root level induce the synthesis of signalling molecules (biologically or chemically active volatile compounds: BVOC or VOC) that allow the communication between plants and other organisms. These compounds are also essential for the indirect defence of plants since they are perceived as "cry for help" from beneficial organisms in the trophic chain, plant-herbivore-carnivore. Despite its crucial importance for the development of the whole plant, the root system has not yet been adequately investigated. In particular, very few information can be found in the literature, on the interaction between the underground and aboveground part of the plant. How do roots and shoots communicate? how do they exchange the essential information to adapt and survive stress situations? The multidisciplinary approach of the proposal provides the possibility, unexplored so far, of facing such topic. This proposal is based on the solid evidences that roots affect the overall plant growth by processes beyond the functions of supplying water and nutrients. Critical experiments indicate that root system signals modulate shoot growth and activity. We relate these findings to a postulated role of root tips as determinants of root architecture and subsequent function. Breakthroughs are targeted by this proposal focusing on the role of roots.

Keywords: root,signalling,bvoc,voc,stress,v403 agriculture related to crop production
Normative Interaction and Law-Making: Regulating Migration in the Maghreb (MIGRINTERACT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-08-01
End date: 2015-07-31
Duration (months): 24.0
Total project cost (EUR): 269743.8
EU funding (EUR): 269743.8
Participants: 1
Project status: CLOSED

This project explores law-making in the domain of migration in the Maghreb as a result of interaction between diverse exogenous and endogenous normative factors. It builds and tests an innovative approach to reforms undertaken since 2003 in three countries, namely Tunisia, Morocco and Mauritania, to improve the knowledge and understanding of legal development in the Maghreb. It unfolds the plurality of interactions that result in the law being reformed in these countries and the country-specificity of law-making in a field where law is being globalised. Drawing on comparative law, international law, sociology of law, human geography and political science, the project examines how recent regulations affecting migration (entry and stay in a territory, exit from the territory, citizenship and asylum) have been thought, elaborated and adopted in each of the three Maghreb countries covered by the project. It therefore goes into the details and mechanisms of law-making and leads to designing a comparative model of normative interactions in national law-making. This project provides an unprecedented analysis of legal development in the Maghreb and a valuable contribution to the understanding of normative interactions in the field of migration. Innovative from theoretical, empirical and methodological perspectives, it develops a coherent analytical framework of law-making, aimed to be replicable across policy and geographical areas. It is hosted in a research centre at Aix-Marseille University, France, which combines excellence in legal research and a unique multidisciplinary academic pool rooted in the Mediterranean. It resorts to field research in Morocco, Tunisia and Mauritania and a network of partners in these countries to benefit from local input and favour knowledge-sharing. This project provides supportive policy tools to strengthen the external dimension of EU’s immigration and asylum policy and a renewed partnership between the EU and its Southern Neighbourhood.

Keywords: migration,mobility,asylum,foreign national,maghreb,law,legal development,law-making,tunisia,morocco,mauritania,refugee
Neural mechanisms underlying rapid modulation of spatial attention in cortex and superior colliculus (SPATIAL ATTENTION)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Portugal
Call:  (FP7-PEOPLE-2012-IIF, 2012)
Start date: 2014-01-01
End date: 2015-12-31
Duration (months): 24.0
Total project cost (EUR): 147210.0
EU funding (EUR): 147210.0
Participants: 1
Project status: CLOSED

We are constantly inundated with a barrage of sensory information. At any given instant, however, only a small key fraction of this sensory world is relevant for taking action. Our brains must select out the critical input and use it to guide behavioral response. We often call this selection process attention. A field mouse, for example, scurrying through the grass scanning for delicious morsels attends to the ground below. The moment, however, the shadow of a hawk flashes by the mouse freezes in an instant attention was shifted from below to the imminent danger in the sky above. Attention is central to sensory processing and critical to survival. It is dynamically moved around to select the key sensory input. These changes in information selection occur extremely rapidly in the brain. This proposal aims to understand the cellular mechanisms driving this selection process. I develop a interdisciplinary approach using a novel spatial attention task in mice, and leverage this genetically tractable animal model, state-of-the art in vivo sub-cellular 2-photon imaging, optogenetics, & patch-clamp recordings to dissect the microcircuits & synaptic mechanisms that mediate these rapid changes in sensory processing. I will be hosted by Dr. Mainen at Portugal’s newly established Champalimaud Neuroscience Program. The systems neuroscience focus of the CNP, my past research experience, scientific interest & career goals makes this proposal the perfect match for both the host and I. This project will not only provide data on fundamental open questions regarding sensation & cognition, it will also allow me to develop a multidisciplinary approach to systems neuroscience. Combining sophisticated behavioral assays with next-gen techniques in optogenetics & imaging, this project puts the host lab and I at the bleeding-edge of systems neuroscience research. By funding this study, the Marie Curie Work Programme will secure its long-held leading role in supporting innovative research.

Keywords: systems neuroscience,electrophysiology,mouse behavior,optogenetics,superior colliculus,attention,prefrontal cortex
The role of dynamic microtubule in the structure and function of dendritic spines (DYNAMICMTINSPINES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2014-04-01
End date: 2016-03-31
Duration (months): 24.0
Total project cost (EUR): 175974.6
EU funding (EUR): 175974.6
Participants: 1
Project status: CLOSED

Synaptic connections within the adult brain are not fixed and stable but remarkably flexible. This reorganisation of synaptic connectivity is a basic principle of neuronal plasticity and believed to represent the cellular basis for learning and memory function. Dendritic spines form the dynamic postsynaptic component of most excitatory synapses in the brain. Recent studies from the host laboratory revealed the invasion of microtubules (MT) into dendritic spines. Several lines of evidence indicate that synaptic activation increases MT entry in spines. However, it remains unclear how synaptic signals trigger intraspinal MTs and what is the effect of MT invasion for spine structure and function. The proposed project is aimed to investigate the functional consequences of dynamic microtubules in spine plasticity. We will combine molecular biology, organotypic slice cultures, quantitative/high resolution microscopy, and electrophysiology to investigate the role of MT based mechanisms in synaptic plasticity. In this application we propose to: Objective 1. Characterise synaptic signals that control MT spine entry. We will analysis different neuronal activation patterns as potential triggers of MT spine invasions. Objective 2. Determine the role of MT spine entry for structural spine plasticity. Functionally, dynamic MTs can contribute to dendritic spine plasticity by regulating intraspinal actin dynamics or cargo transport into spines. We will test whether MT entry stabilize/modify the invaded spine in slice cultures and analyse the role of dynamic MT in the development of immature dendritic protrusions. Objective 3. Examine the role of dynamic MT for cargo trafficking into spines. The role of dynamic MT for transport of cargo into spines will be studied by analysing kinesin/dynein motor dynamics during spine invasion of MTs. The results of this project will contribute to the fundamental understanding of spine and synapse plasticity.

Keywords: synaptic plasticity,hippocampus,cytoskeleton,structural spine dynamics,actin,microtubules,eb3,live cell imaging,dendritic spines,synaptic cargo trafficking
DEEP BRAIN TISSUE IMAGING OF GLUTAMATE NMDAR (DEEPNMDAR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-07-01
End date: 2015-06-30
Duration (months): 24.0
Total project cost (EUR): 194046.6
EU funding (EUR): 194046.6
Participants: 1
Project status: CLOSED

Unrevealing the rules that govern the surface trafficking and membrane stabilization of neurotransmitter receptors, in particular the NMDAR is crucial for our understanding of several physiopathological brain processes. Over the past few years, scientists have shown that neurotransmitter receptors diffuse inside and out of synapses in cultured neurons using single molecule approaches. These findings drastically changed the way we understand synaptic transmission and adaptation. The proposed project aims to study the surface diffusion of NMDAR in intact hippocampal slices, providing the first functional map of such key receptors in native neuronal networks. Due to the difficulties of imaging single molecules in high background noise tissue, a multidisciplinary approach will be adopted using quantum dots and single walled nanotubes to track single NMDAR neurotransmitters. The success of the project will be a real breakthrough in neurobiology of synapses and in single molecule imaging techniques, conjugating state of the art knowledge in neurosciences and nanophotonics.

Keywords: neuroscience,nmda receptor,biophysics,single molecule tracking,quantum dots,single walled nanotubes
Guiding Light through Disorder in Adaptive Photonic Resonator Arrays (PHAROS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Condensed matter physics
Countries involved: Netherlands,France
Call:  (ERC-2011-StG_20101014, 2011)
Start date: 2011-10-01
End date: 2017-01-31
Duration (months): 64.0
Total project cost (EUR): 1496400.0
EU funding (EUR): 1496400.0
Participants: 3
Project status: CLOSED

Planar photonic crystals are dielectric nanostructures that are pursued worldwide as a platform for integrated nanophotonic circuits. Such circuits will process signals coded in light and will consist of thousands of basic components such as resonant nanocavities. At present, unavoidable nanometer-scale disorder makes such large-scale integration impossible. Disorder causes the resonances of the nanocavities to shift randomly, resulting in Anderson localization, an interference effect that blocks the propagation of light. Anderson localization – predicted in 1958 by Nobel Prize winner Philip Anderson – is an intriguing scientific phenomenon as well as a serious threat to applications. I propose to create adaptive nanophotonic systems. In these systems, I will use a spatially modulated light beam to modify the resonance frequency of each individual nanocavity. After adaptive tuning, the spatially structured light exactly counteracts the disorder and guides signals safely through the nanophotonic circuit. Effectively the signals will propagate in a perfect nanophotonic structure. As a second main innovation, I will employ an ultrafast structured light beam to write new, ordered and functional patterns into the circuit. This transformational technology will enable applications wherein optical circuits become fully programmable. The circuit will be modified dynamically in less time than that needed for a photon to pass through it. Spatial light modulators will enable us to address and control thousands of individual nanophotonic components. Our dynamic and adaptive nanophotonic system will enable new technology, such as dynamically tunable delay lines, and open up new regimes of light propagation: the crossover regime of Anderson localization, ultraslow light that propagates scarcely faster than sound, and dynamic light propagation where the time dependence of the nanostructure drastically influences the flow of light.

Keywords: photonic crystals,slow light,nanophotonics,metamaterials,photons,anderson localization,light scattering,metal-insulator transitions
All Glass Mid Temperature Direct Flow Thermal Solar Vacuum Tube (SOLEGLASS)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SME associations
Action type: Research for the benefit of specific groups
Countries involved: Croatia,Italy,Spain,Switzerland,United Kingdom,Spain,Austria,North Macedonia,Croatia
Call:  (FP7-SME-2011, 2011)
Start date: 2011-09-01
End date: 2014-08-31
Duration (months): 36.0
Total project cost (EUR): 2817325.6
EU funding (EUR): 2130423.0
Participants: 12
Project status: CLOSED

The strategic overall objective of this project is to produce the highly innovative product in the Solar Thermal market segment, the All Glass Mid Temperature Direct Flow Thermal Solar Vacuum Tube (SOLEGLASS in the future text). That will be achieved by combining the latest cutting edge technology developments in Solar Thermal and Glass industries and the comprehensive and focused research activities to be performed within this project backed with technological integration activities. The SOLEGLASS will enable further development of the innovative types of solar collectors within this project what will ultimately stimulate implementation of enhanced and more efficient Solar Thermal applications for the heat production. Thermal solar market is rapidly growing today in the world at all levels, indifferently whether it is related to the application field or temperature levels. Different application or temperature levels are meeting different complexity issues in product or technology implementation. In this project we are particularly targeting the mid temperature range of thermal solar applications from 100 deg C up to 300 deg C. Mid temperature solar thermal heat generation is combinable with a whole series of power generation, industrial and home applications as: o Industry processes heat o Solar Cooling and Heating, residential and service o Solar power plants Products that we are proposing to develop are designated to the wide population of users which are among others members of the partnering SME-AGs (Croatian Chamber of Economy – CCE, Milan Chamber of Commerce – CCIAAMI and the Asociación Nacional de Fabricantes de Bienes de Equipo – SERCOBE), their national complementary associations and the EU umbrella Solar Thermal associations that are supporting this project.

Keywords: borosilicate glass,glass bellow,mid temperature,antireflective coating,absorptive coating
Development of microRNA Medicines for Cardiac Metabolic Diseases; A Targeted European Exchange Programme (CARDIOMIR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Industry-Academia Partnerships and Pathways
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands,Belgium,Germany,Denmark
Call:  (FP7-PEOPLE-2011-IAPP, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 1667076.0
EU funding (EUR): 1667076.0
Participants: 4
Project status: CLOSED

An urgent need exists for more specific treatment options to target the metabolic changes and the related inflammatory pathways during HF. Targeting microRNAs (miRNAs)-small RNAs implicated in protein regulation- represents a unique possibility to make novel medicines against HF. In view of the central role of inflammatory pathways in the metabolic syndrome, they expect inflammation miRNAs to be excellent targets to treat HF. Three partners will form a focused and natural industry-academy partnership where essential expertise in clinical and experimental miRNA biology, systems biology and drug development is exchanged. The common goal of the partners is to discover novel miRNAs implicated in the cardiac metabolic disease, to develop medicines targeting these miRNAs, and finally test these innovative miRNA medicines in the metabolic risk induced HF. The project team proposes to support 10 experienced and 1 early stage researchers under the current IAPP Programme. Two of the experience researchers will be recruited for the project. All the researchers will undergo intersectorial movement, either from academia to industry or vice versa. The CardiomiR project aims: • To identify miRNAs that are implicated in adverse cardiac inflammation and metabolic changes resulting in HF, and treat HF using LNA-antimiR therapeutics targeting these miRNAs. • To exchange researchers to be able to productively combine the skills and know-how of antimiR-drug discovery and development, cardiac disease biology as well as systems biology and omics data analysis. • To achieve this, a concerted collaborative effort, exchange and training is proposed here between two academic and one industrial partner University Maastricht (UM, partner 1) , University of Liège (ULG, partner 2) and SANTARIS Pharma (SANTARIS, partner 3) This project consists of 3 RTD work package, a secondment/recruitment workpackage and will concentrate on dissemination (IPR-related) and management.

Keywords: health sciences,microrna,cardiology