Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Deep understanding and modelling of the hierarchical structure of Prosody (ProsoDeep)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-18
End date: 2019-01-17
Duration (months): 16.0
Total project cost (EUR): 123384.0
EU funding (EUR): 123384.0
Participants: 1
Project status: CLOSED

The prime objective of the ProsoDeep project is to gain a deeper understanding of the language of prosody through the analysis of all the levels in the production hierarchy of prosody. In particular, it will exploit the benefits of the top-down and bottom-up approaches through their incorporation within a Deep Prosody Model (DPM). The DPM will facilitate the advancement of speech technologies that rely both on the synthesis of prosody, e.g. text-to-speech (TTS) systems, and its analysis, e.g. speech emotion recognition (SER). To reach this objective the project will draw on a variety of scientific fields, including signal processing, physiology of prosody production and biomechanics, linguistics, and machine learning, and will also be augmented with respiratory measurements.

Keywords: prosody,speech,speech synthesis,intonation
States, Nationalism, and the Relationship between Ethnic Diversity and Public Goods Provision (ETHNICGOODS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Spain
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-10-01
End date: 2025-09-30
Duration (months): 60.0
Total project cost (EUR): 1985088.0
EU funding (EUR): 1985088.0
Participants: 1
Project status: SIGNED

Around the world, nationalist politicians see migrants and ethnic minorities as undeserved receivers of public goods. What underpins these exclusionary claims is the thesis that ethnic diversity impedes the prospects of economic progress and social welfare. Does this thesis withstand systematic inquiry? At a first glance, there are plenty of studies that link ethnic heterogeneity to the underprovision of public goods. An influential literature in political economy asserts a strong association between high levels of diversity and low levels of public service provision such as schooling or health care. States, Nationalism, and the Relationship between Ethnic Diversity and Public Goods Provision [ETHNICGOODS] aims to revisit and challenge this conventional wisdom, and the doggedly ahistorical perspective it implies. Instead of treating ethnic diversity as exogenous, the project explores the role of historical patterns of nation-building and state institutional development. I expect different nation-building modes—that is, whether states seek to assimilate, accommodate, or exclude minorities—to have distinct consequences for contemporary levels of diversity and collective goods provision. I further expect historical variations in the capacity of states to provide public goods to affect contemporary levels of heterogeneity and public goods provision. To develop and test this theoretical argument on a global scale, ETHNICGOODS will create two new, publicly available datasets and combine comparative-historical case studies and statistical analysis. With this ambitious focus the project aims to make a major contribution to our understanding of ethnic diversity, injecting a historical perspective into debates around the political and developmental consequences of heterogeneity. Finally, by connecting with a range of academic and non-academic audiences, ETHNICGOODS will influence public debates about ethnic diversity and its effects.

Keywords: comparative politics,political sociology,comparative historical sociology,race and ethnicity,nationalism,state formation,mixed methods,public goods provision
Climate Variability and Security Threats (CLIMSEC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Norway
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-09-01
End date: 2021-06-30
Duration (months): 70.0
Total project cost (EUR): 1996945.0
EU funding (EUR): 1996945.0
Participants: 1
Project status: CLOSED

Recent uprisings across the world have accentuated claims that food insecurity is an important trigger of political violence. Is the Arab Spring representative of a general climate-conflict pattern, where severe droughts and other climate anomalies are a key driving force? Research to date has failed to conclude on a robust relationship but several notable theoretical and methodological shortcomings limit inference. CLIMSEC will address these research gaps. It asks: How does climate variability affect dynamics of political violence? This overarching research question will be addressed through the accomplishment of four key objectives: (1) Investigate how food security impacts of climate variability affect political violence; (2) Investigate how economic impacts of climate variability affect political violence; (3) Conduct short-term forecasts of political violence in response to food and economic shocks; and (4) Develop a comprehensive, testable theoretical model of security implications of climate variability. To achieve these objectives, CLIMSEC will advance the research frontier on theoretical as well as analytical accounts. Central in this endeavor is conceptual and empirical disaggregation. Instead of assuming states and calendar years as unitary and fixed entities, the project proposes causal processes that act at multiple temporal and spatial scales, involve various types of actors, and lead to very different forms of outcomes depending on the context. The empirical component will make innovative use of new geo - referenced data and methods; focus on a broad range of insecurity outcomes, including non-violent resistance; and combine rigorous statistical models with out-of-sample simulations and qualitative case studies for theorizing and validation of key findings. Based at PRIO, the project will be led by Research Professor Halvard Buhaug, a leading scholar on climate change and security with strong publication record and project management experience.
European Rare dIsease research Coordination and support Action (ERICA)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Health care provision and integrated care
Action type: Coordination and support actions
Countries involved: Spain,Germany,Germany,Germany,Germany,Germany,Italy,Austria,Spain,Italy,Italy,France,France,France,France,Netherlands,Netherlands,Netherlands,Netherlands,Netherlands
Call: Coordination of clinical research activities of the European Reference Networks (H2020-SC1-2020-Single-Stage-RTD, 2020)
Start date: 2021-03-01
End date: 2025-02-28
Duration (months): 48.0
Total project cost (EUR): 2313808.75
EU funding (EUR): 2313808.75
Participants: 27
Project status: SIGNED

Rare diseases are defined as diseases that affect not more than 1 person per 2000 in the European population. While individual rare diseases affect only a small percentage of the population, they collectively affect up to 30 million people in the EU. To facilitate access to high quality cross-border healthcare and promote and foster cooperation on rare disease healthcare between member states, 24 European Reference Networks (ERN) are currently active. The aim of the ERICA consortium, in which all 24 ERNs take part, is to build on the strength of the individual ERNs and create a platform that integrates all ERN’s research and innovation capacity. Through knowledge sharing, engagement with stakeholders in the rare disease domain and assembly of transdisciplinary research groups working across the global health spectrum ERICA strives to reach the following goals: • new intra- and inter-ERN rare disease competitive networks; • effective data collection strategies; • better patient involvement; • enhanced quality and impact of clinical trials; • increased awareness of ERN’s innovation potential; Through integration of ERN research activities, outreach to European research infrastructures to synergistically increase impact and innovation ERICA will strengthen the research and innovation capacity of the ERNs. This will result in safe, accessible and efficient access of therapies for the benefit of patients suffering from rare diseases and conditions.

Keywords: european research networks,rare disease,research,innovation,irdirc goals
Trace Amine-Associated Receptor 1 (TAAR1) agonists in a chemogenetic/molecular imaging model of increased dopamine synthesis capacity (Ki) (TACtIK)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: SIGNED

My research plan aims at generating an innovative chemogenetic/positron emission tomography (PET) imaging translational model of striatal dopamine (DA) over-reactivity, the most well-established pathophysiological mechanism underlying schizophrenia. I will use this platform to test the therapeutic efficacy of antipsychotic compounds with a totally new mechanism of action, i.e. targeting the trace amine-associated receptor 1 (TAAR1). Pre-clinical findings will have immediate translation to humans. I envisage a two-fold utility of this platform for the scientific community: 1) development of innovative therapeutic strategies for psychotic disorders; 2) ask fundamental questions about the pathophysiology of schizophrenia. A substantial share of patients treated with available antipsychotics do not respond and/or experience undesirable side effects. Available antipsychotics do not target the neurobiological mechanisms underlying schizophrenia symptoms, i.e., increased pre-synaptic DA synthesis capacity (Ki) in the striatum. They rather rely on blockade of DA receptors post-synaptically, possibly causing iatrogenic DA super-sensitivity. Therefore, there is a quest for improved therapeutic strategies, addressing DA over-reactivity. A novel target is represented by TAAR1, a G protein-coupled receptor that has been found to crosstalk with the DAergic system. Based on these premises, the objectives of this project are: -Work package 1. To develop a chemogenetic translational mouse model of increased striatal Ki. We will use [18F]-FDOPA PET imaging to determine if selective manipulation of midbrain neuron firing increases Ki. -Work package 2. To determine if TAAR1 agonists (TAAR1 toolbox) decrease striatal Ki in the model from WP1. We will ascertain whether TAAR1 is necessary for the effect on Ki, using TAAR1 knock-out (KO) mice. -Work package 3. To determine whether TAAR1 toolbox modulate Ki in patients with a diagnosis of schizophrenia, applying [18F]-FDOPA PET imaging.

Keywords: dopamine synthesis capacity,chemogenetics,positron emission tomography,antipsychotic drugs,trace amine associated receptors
Robots learning about objects from externalized knowledge sources (RoboExNovo)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Italy,Italy
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-06-01
End date: 2021-05-31
Duration (months): 72.0
Total project cost (EUR): 1496277.0
EU funding (EUR): 1084873.0
Participants: 2
Project status: CLOSED

While today’s robots are able to perform sophisticated tasks, they can only act on objects they have been trained to recognize. This is a severe limitation: any robot will inevitably face novel situations in unconstrained settings, and thus will always have knowledge gaps. This calls for robots able to learn continuously about objects by themselves. The learning paradigm of state-of-the-art robots is the sensorimotor toil, i.e. the process of acquiring knowledge by generalization over observed stimuli. This is in line with cognitive theories that claim that cognition is embodied and situated, so that all knowledge acquired by a robot is specific to its sensorimotor capabilities and to the situation in which it has been acquired. Still, humans are also capable of learning from externalized sources – like books, illustrations, etc – containing knowledge that is necessarily unembodied and unsituated. To overcome this gap, RoboExNovo proposes a paradigm shift. I will develop a new generation of robots able to acquire perceptual and semantic knowledge about object from externalized, unembodied resources, to be used in situated settings. As the largest existing body of externalized knowledge, I will consider the Web as the source from which to learn from. To achieve this, I propose to build a translation framework between the representations used by robots in their situated experience and those used on the Web, based on relational structures establishing links between related percepts and between percepts and the semantics they support. My leading expertise in machine learning applied to multi modal data and robot vision puts me in a strong position to realize this project. By enabling robots to use knowledge resources on the Web that were not explicitly designed to be accessed for this purpose, RoboExNovo will pave the way for ground-breaking technological advances in home and service robotics, driver assistant systems, and in general any Web-connected situated device.

Keywords: life long learning,autonomous robot systems,visual and multi modal learning
Flexible Heat and Power, Connecting heat and power networks by harnessing the complexity in distributed thermal flexibility. (FHP)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: A single, smart European electricity grid
Action type: Research and Innovation actions
Countries involved: Spain,Belgium,Sweden,Sweden,Belgium,Czechia,Netherlands,Netherlands,Netherlands
Call: Next generation innovative technologies enabling smart grids, storage and energy system integration with increasing share of renewables: distribution network (H2020-LCE-2016-SGS, 2016)
Start date: 2016-11-01
End date: 2019-10-31
Duration (months): 36.0
Total project cost (EUR): 3823606.25
EU funding (EUR): 3801997.75
Participants: 10
Project status: CLOSED

The annual space heating and cooling energy consumption in Europe is almost 3,500TWh. In 2012, in EU28 the electricity consumption ratio was around the 20% of the total energy consumption, from which 30% was consumed in the residential and 30% in the services sectors. From these proportions, air conditioning represents 17% of the total electricity consumption in the EU27 residential buildings. In the EU tertiary sector the electric space and water heating system represent 19.22%, the ventilation 12.47%, the commercial refrigeration 8.57% and the air conditioning 2.86% of the buildings electricity consumption. Heating, ventilation and air conditioning system’s electricity consumption of a building can represent between the 30% and 40% of the total energy consumption. The inertia of these power to heat solutions constitute an enormous potential for electric flexibility usable for absorbing the excess of renewable generation and avoiding curtailment while managing local power congestion, voltage stability in the grid and avoiding reversal power flows, as well as minimizing RES production imbalance. That is, DER with thermal inertia can provide services to RES owners, grid operators, aggregators and actors on the power market, while saving energy in the buildings. In fact, flexibility harnessing using heat to power solutions enables to deploy large-scale renewable throughout Europe successfully. The Flexible Heat and Power (FHP) project will develop a Power-to-Heat (and Cooling) solution package that manages this complexity through an easily accessible interface aimed at buildings and power grid actors. A practical prototype will be developed and deployed in two different demonstration scenarios in The Netherlands and Sweden representing diverse parts of the European power grid. FHP has the potential to provide total thermal flexibility with the aim of increasing the share of renewables by 22% over the total electric consumption from current technical limits (40%).

Keywords: power to heat,renewable curtailment mitigation,increase res penetration,synergies between energy networks,cost effective conversion of excess electricity,products on the market in 5 10 years
A study of the roles of the immune and inflammatory systems in hypertension. (InflammaTENSION)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: United Kingdom,United Kingdom
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-05-01
End date: 2024-04-30
Duration (months): 84.0
Total project cost (EUR): 1957573.75
EU funding (EUR): 165243.75
Participants: 2
Project status: SIGNED

Hypertension is a common disease impacting 1 billion people worldwide, which leads to catastrophic cardiovascular complications. The cause of primary hypertension is unknown and the disease remains uncontrolled in many patients. By interrogating the key hypothesis that inflammatory dysregulation fundamentally controls development of hypertension and vascular remodelling, InflammaTENSION provides a new paradigm for the management of the disease, with the potential to lead to identification of novel therapeutic targets to control hypertension. InflammaTENSION will result in the discovery of novel biomarkers, capable of identifying patients who could benefit from such immune targeted therapies. Importantly, we already made the seminal observation that the immune system not only mediates target organ damage, but is essential for the development of hypertension. This finding has initiated numerous studies, that defined the roles of pro-inflammatory T cells, monocytes and anti-inflammatory T regulatory cells. However, our current knowledge remains very fragmented and so far has not been applied to human pathology. InflammaTENSION will for the first time advance the knowledge procured in rodent models into human studies. By combining clinical translational and model mechanistic studies it will identify novel inflammatory factors that can control immune mechanisms of hypertension. We will: (1) characterize the immunophenotypic signature of human hypertension; (2) define key concepts in cytokine biology of hypertension with TNF-α and IL-6 as key exemplars; (3) understand how chronic cytokines regulate the T cell dependent mechanisms of hypertension. InflammaTENSION will go beyond current state-of-the-art through comprehensive combination of immunology and cardiovascular medicine to create a new understanding of how the immune system may lead to human hypertension and will have major impact on the field, enabling translation of these exciting findings to clinical practice.

Keywords: hypertension,blood pressure,endothelium,inflammation,vascular,perivascular
Eschatological time as women’s time? Gendered temporality and female holiness in Early Christianity and Byzantium (Gentime)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: CLOSED

This proposal investigates the nexus between time and the construction of the feminine in Late Antique and Byzantine hagiographical discourses. By looking both at ways time is experienced through the body and construed by society and religion, GenTime engages with a highly debated problem in Byzantine studies: why did female saints progressively disappear over the Byzantine millennium? GenTime argues that this trajectory has to be understood against the eschatological expectations shaping early Christian ideals of female holiness. In the 2nd and 3rd century the impending end of times subsumed any other temporality and led to the subversion of traditionally construed “women’s time”. Once the Roman Empire became Christian, the eschatological horizon was reinforced in Byzantium by the widespread circulation of apocalyptic motives, adopted by the Imperial power for political and moral purposes. Eschatologically-motivated narrative patterns about women saints became entrenched and their ongoing success made it hard to accommodate new experiences of holiness when other models of lay temporality eventually emerged during the Middle Byzantine era. GenTime looks at stories about women saints produced between the 2nd and the 13th century CE by adopting a longue durée perspective and using narratology to analyze how patterns of temporalities are inscribed in the text. It builds on feminist phenomenology to highlight the persistence of strategies used to control women’s time within patriarchal social orders. GenTime works with medieval sources and it reflects on the dialectics between integration/assimilation, minority/majority cultures, gender/societal values, all of them of major concern in modern societies. In doing so, it raises awareness about the ways gendered discourses of time have historically been used to promote lifestyles that, ultimately, have less to do with women’s empowerment and more with power struggles between competing social groups.

Keywords: byzantine studies,gender studies,religious studies