Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
the unseen spaces of extended urbanization in the North Sea (OCEANURB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-01
End date: 2019-02-28
Duration (months): 18.0
Total project cost (EUR): 133199.1
EU funding (EUR): 133199.1
Participants: 1
Project status: CLOSED

This proposal investigates the ocean as a spatial realm and the site of unfolding urbanization processes- a challenging new field within urban studies. The project aims to, 1. promote a holistic, inter-disciplinary view of the ocean which connects its geo-physical, biological and socio-economic dimensions through spatial means. Rather than a peripheral realm, or a void, the ocean is placed at the geographical and epistemological centre of current territorial developments, which represents a paradigm sift in perspective and is beyond the state of the art. The project proposes methods of spatial analysis that enable the invisible urbanization processes in ocean space to be represented, evaluated and shared as data to a range of stakeholders and academics- a new contribution to urban theory. 2. Support theoretical reflections by producing a case-study on current urbanization processes in the North Sea, in collaboration with a territorial study of North Sea settlement led by the supervisor’s chair. The two-way transfer of knowledge takes place across the land-sea threshold, demonstrating how the greater sea-space has influenced urban development. The North Sea project achieves a continuity of analysis across the interlocking land- and sea-sides – something that has never been achieved at the scale of the Sea as a whole and therefore stands to rewrite understandings of regional urbanization. 3. Critically examine and theorize the contradictory spatial dimensions of maritime transport as a sub-topic- although the backbone of globalization, consuming increasing on- and offshore areas, carrying increased loads, shipping’s spatial typologies are elusive, lacking architectural quality and interaction with urban contexts. Through the project the researcher will profit from first-hand experience and exchange with the European hub of maritime trade and an excellent research environment, gaining new specialist knowledge in the field which is applied to enrich urban research.

Keywords: territory,seascape,maritime trade,globalization,infrastructure,transboundary,marine spatial planning,ocean space,planetary urbanization
Solitude: Alone but Resilient (SOAR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: United Kingdom,United Kingdom
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 1482391.0
EU funding (EUR): 1429700.84
Participants: 2
Project status: SIGNED

It is undeniable that social connections and interactions are key to the human experience. Perhaps for this reason, laypeople and scientists alike have assumed that being alone is aversive, a state inexorably tied to lonely emotions and sense of isolation. Yet solitude is experienced daily by nearly everyone, and though it can be negative it can also be a constructive and rewarding time. What makes some more psychologically resilient to solitude and why do some experience fewer of the negative and more of the positive emotions associated with this potentially challenging state? The SOAR project will integrate fragmented literatures and model contributions of predictors at event, individual, and cultural levels. This ambitious three-part project consists of complementing qualitative and quantitative approaches and will be the first to build a conceptual model through open science methods, offering intrinsic value to research conducted outside of the field of solitude. WP1 explores what solitude, and psychological resilience within it, means to people in different circumstances through semi-structured interviews, imagery, and written narratives. WP2 tests predictors of psychological resilience within solitude to develop a conceptual model, first with a novel diary study approach to capture solitude as it occurs, then with a large-scale multi-nation assessment, and finally with older adults. Finally, WP3 develops a resilience in solitude intervention as an experimental test of the model, and conducts a field experiment with older adults. The radical shift in theory, and use of novel, multifaceted approaches, will guide our understanding of how humans respond in the immediate absence of social connections, and pave the way for further understanding self-processes, the role of the self in relation to interpersonal interactions and society, and psychological resilience more broadly.

Keywords: well being,flourishing,solitude,aging,culture
Revealing Allele-level Regulation and Dynamics using Single-cell Gene Expression Analyses (Allelic Regulation)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Sweden
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-07-01
End date: 2020-12-31
Duration (months): 66.0
Total project cost (EUR): 1923060.0
EU funding (EUR): 1923060.0
Participants: 1
Project status: CLOSED

As diploid organisms inherit one gene copy from each parent, a gene can be expressed from both alleles (biallelic) or from only one allele (monoallelic). Although transcription from both alleles is detected for most genes in cell population experiments, little is known about allele-specific expression in single cells and its phenotypic consequences. To answer fundamental questions about allelic transcription heterogeneity in single cells, this research program will focus on single-cell transcriptome analyses with allelic-origin resolution. To this end, we will investigate both clonally stable and dynamic random monoallelic expression across a large number of cell types, including cells from embryonic and adult stages. This research program will be accomplished with the novel single-cell RNA-seq method developed within my lab to obtain quantitative, genome-wide gene expression measurement. To distinguish between mitotically stable and dynamic patterns of allelic expression, we will analyze large numbers a clonally related cells per cell type, from both primary cultures (in vitro) and using transgenic models to obtain clonally related cells in vivo. The biological significance of the research program is first an understanding of allelic transcription, including the nature and extent of random monoallelic expression across in vivo tissues and cell types. These novel insights into allelic transcription will be important for an improved understanding of how variable phenotypes (e.g. incomplete penetrance and variable expressivity) can arise in genetically identical individuals. Additionally, the single-cell transcriptome analyses of clonally related cells in vivo will provide unique insights into the clonality of gene expression per se.
Policies and tools for mainstreaming 1.5° Lifestyles (EU 1.5 Lifestyles)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Fighting and adapting to climate change
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Germany,Sweden,Hungary,Finland,Latvia,Netherlands
Call: Scientific support to designing mitigation pathways and policies (H2020-LC-CLA-2020-2, 2020)
Start date: 2021-05-01
End date: 2025-04-30
Duration (months): 48.0
Total project cost (EUR): 4945241.25
EU funding (EUR): 4945241.25
Participants: 10
Project status: SIGNED

The IPCC concludeThe IPCC concludes in their Special Report on Global Warming that limiting global temperature increase needs demand-side actions and lifestyle changes. Previous attempts to realise demand-side changes have been hampered by several factors: First, there is very limited quantitative data showing how much a proposed change in lifestyle would contribute to climate change mitigation. Thus, policy makers and citizens lack guidance to make informed choices. Second, there is still limited evidence of public acceptance of drastic changes. This has led to internationally uncoordinated policies and to policies that will very likely fall short on having sufficient impact. Third, policies have usually promoted changes of individual behaviour without addressing structural constraints or structural drivers of unsustainable lifestyles. This has led to policies that remain ineffective and frustrate citizens who wish to make positive lifestyle choices. We aim to address all three of the above issues, by connecting an analysis of individual lifestyle perspectives, on household level, with policies and socio-economic structures, on all levels from international to local. The analysis will be structured according to the emerging 1.5-degree lifestyles approach, which members of the consortium have helped to define. The advantage of a lifestyle-oriented approach is to link concrete transformations of lifestyle by individuals to transformations of the structural context by policies, economic, and societal institutions. This inclusive approach is original in terms of a research strategy. In practical terms, it is very promising as it offers concrete guidance and as it can be scaled to political, social, and economic capacities on regional to (supra-) national levels. We pursue our aims using quantitative and qualitative methods, country-level assessments and sector-based case studies, as well as innovative participatory formats and a broad range of communication methods.

Keywords: households,structural barriers,rebound,economic impacts,citizen labs,multi stakeholder labs,footprint,stock taking,communication strategies,structural reforms,practical tools
Integration of Capacitor, Thermoelectric and PhotoVoltaic thin films for efficient energy conversion and storage (CapTherPV)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Portugal
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-07-01
End date: 2022-07-31
Duration (months): 85.0
Total project cost (EUR): 1999375.0
EU funding (EUR): 1999375.0
Participants: 1
Project status: SIGNED

The possibility of having a unique device that converts thermal and photonics energy into electrical energy and simultaneously stores it, is something dreamed by the PI since the beginning of her research career. To achieve that goal, this project aims to gather, in a single substrate, solar cells with up-conversion nanoparticles, thermoelectrics and graphene super-capacitor, all made of thin films. These three main components will be developed separately and integrated sequentially. The innovation proposed is not limited to the integration of components, but rely in ground-breaking concepts: 1) thermoelectric elements based on thin film (TE-TF) oxides; 2) plasmonic nanoparticles for up conversion of near infrared radiation to visible emission in solar cells; 3) graphene super-capacitors; 4) integration and optimization of all components in a single CapTherPV device. This ambitious project will bring new insights at large area, low cost and flexible energy harvesting and comes from an old idea of combining energy conversion and storage that has been pursued by the PI. She started her career in amorphous silicon thin film solar cells, later she started the development of thin film batteries and more recently started a research line in thermoelectric films. If approved, this project will give financial support to consolidate the research being carried out and will give independence to the PI in terms of resources and creative think. More importantly, will facilitate the concretization of the dream that has been pursued with hard work.
Deciphering and targeting the molecular mechanisms that drive the mechanically-induced cancer metastasis to bones. (MECHANiCM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-12-06
End date: 2024-08-30
Duration (months): 24.0
Total project cost (EUR): 203852.16
EU funding (EUR): 203852.16
Participants: 1
Project status: CLOSED

Mechanical abnormalities of the tumor microenvironment (TME) have gained much attention over the last decades as potent drivers of tumor progression. These abnormalities include compressive forces that generate the so-called solid stress. Solid stress is suggested to affect the metastatic potential of several tumor types, including breast cancer, however the exact molecular mechanisms involved remain to be explored. Once cancer cells have left the primary tumor site and entered into the blood stream are also exposed to shear stress exerted by blood flow. Shear stress is considered to be lower during flow, and higher during intravascular arrest. The arrested cancer cells must develop mechanisms of adhesion to efficiently resist such forces for successful extravasation, however the involved mechanisms are elusive. In particular, the third most common secondary tumor site for breast cancer is bone. There, cancer cells interact with bone-specific cells, that are also exposed to shear forces due to blood flow in the bone environment. To this end, the applicant proposes to test the hypothesis that the presence of solid stress in TME, and shear stress in the blood stream are important physical parameters that could trigger cancer cell metastasis. Therefore, it is highly value to identify the molecular mechanisms involved to target and reverse the metastatic process. The proposed research combines knowledge in the fields of bone and cancer biology and mechano-pathology, bioengineering and biophysics, and cutting-edge techniques. A pharmaceutical screening will be also performed in vitro and in vivo to suggest possible therapeutic interventions to prevent breast cancer metastasis. In the proposed project, the fellow will acquire scientific and complementary skills according to her personalized career development plan, while through advanced training and inter-sectoral mobility she will reach a position of professional maturity in research.

Keywords: cancer biology,bone biology,bone metastasis,tumor microenvironment,tumor mechano pathology,bone mechanics,solid stress,shear stress,mechano transduction,cancer bone cell crosstalk
Investigating Proxies for Understanding Trajectories: Heritage Language Maintenance and Child Second Language Acquisition in Refugee Contexts (INPUT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-03-01
End date: 2023-08-28
Duration (months): 24.0
Total project cost (EUR): 214158.72
EU funding (EUR): 214158.72
Participants: 1
Project status: SIGNED

Investigating Proxies for Understanding Trajectories: Heritage Language Maintenance and Child Second Language Acquisition in Refugee Contexts (INPUT) will examine heritage language and child second language development in the European refugee context. INPUT will significantly add to a sub-field of bilingualism studies, Heritage Language Bilingualism (HLB), by studying refugee heritage speakers in Europe, an understudied subset of HLB. This empirical study will investigate linguistic and extra-linguistic variables affecting the development of both the societal majority language and the heritage language with the goal of impacting education policy development. Heritage language Syrian Arabic in Germany and second language German will be investigated with a focus on 6- to 12-year-old children to examine developmental trajectories. The overall research objective is to understand the extent to which increased or reduced heritage language exposure affects heritage language and child second language trajectories and outcomes. For Europe, supporting refugee youth can have significant impact towards the publicly stated goal of integrating this population into their newly adopted countries. One major impediment to this integration is their successful acquisition of the societal majority language while maintaining and developing the first language. Our hypothesis is that support for continued development in the heritage language will improve second language development with knock-on effects for the academic achievement of refugees. At present, heritage language support and training varies tremendously all over Europe. Project findings will be relevant especially for policy makers, teachers, school principals and HLB communities in European countries that have seen a notable increase of Syrian Arabic heritage speakers. To date, most heritage language studies have focused exclusively on the minority language, INPUT helps to fill an important gap by focusing on both languages.

Keywords: bilingualism,heritage language speakers,child second language development,input,literacy
High Accuracy, Cost-Effective and Eco-Friendly Dredging Solution (Toolbot)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-09-01
End date: 2020-02-29
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Dredging is an essential part of economy, allowing waterways and relevant infrastructure to operate at optimal capacity in favour of global distribution of goods. It involves the removal of particles of sand, clay, silt and other substances deposited in the bottoms of coastal areas, ports and estuaries, navigable river beds... and is necessary to maintain the draft of the ports and fill their extensions, eliminate contaminated sediments or mitigate the effects of storms, creation of land and beaches, fishing and aquaculture, etc. Impacts includes turbidity at the point of dredging and at the point of discharge, and mobilisation, dissolution and dispersion of pollutants retained in the sediments. Actually, dredging activities are being reoriented due to environmental awareness and legal restrictions. Toolbot offers a solution for the last mile dredging operations where spots are hard to reach, where underneath infrastructures must be maintained or when conventional methods are oversized to actuate with precision. We make possible recurrent maintenance dredging in ports and marinas even in water dams due to an easy mobilisation by road truck using an underwater dredger vehicle. Our high accuracy Dredging ROV (Remote Operated Vehicle) prototype was developed through the Spanish CDTI in the e-Corydora project, finished in 2018, and it is currently in a TRL 7 and in the patent process in the EPO. Aiming at having a cost-effective and ecological integral dredging system, we have also developed a complementary discharge buoy that redirects the dredged sediments to the seabed avoiding the water column contamination. In this way, the idea is disruptive and breaks the market.

Keywords: rov dredging,autonomous dredging,high resolution and last mile dredging
The Spot Demetallizing Film - a unique, environment and health-friendly technology for effective food packaging. (SD4Food)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Poland
Call: Accelerating the uptake of nanotechnologies advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-12-01
End date: 2017-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Each year ca. 89m tonnes of food in EU is irrecoverably wasted (i.e. 179 kg per capita) and the projection for 2020 – if no action will be taken – is 126m tonnes (i.e. a 40% increase). At the same time ca.79m EU citizens live beneath the poverty line and ca.16m strongly depend on food aid from the charitable organizations. A lot of food is thrown into the garbage just because the expiry date does not provide an accurate indication of the food`s freshness, instead reflecting the worst case scenario of how long a product should be safe to eat. The SDF is a novel technology enabling local removing of metallized layer on the foil (film) in a needful spot, allowing consumers to decide if to eat or dispose the product, based on the real freshness status of the food (the film becomes fully transparent for the human eye exactly at the point where it is required). Currently, no technology with such potential exists on the market. Packaging made of the metallized film is used for keeping the food product fresh and in good sanitary conditions. The metallized film has similar barrier properties as aluminium film (level of steam and oxygen permeability, high protection against light and bacterial microflora), but does not fracture or rip. Production of metallized film requires 130x less aluminium and production costs are 5x lower than in case of the aluminium film. That`s why the metallized film is used for packaging of candy-bars, candies, biscuits, ice cream, coffee, tea, cereals, fish, meat, and even gifts. The SDF tackles existing market needs, enables food producers to keep the product in good storage conditions and simultaneously show how does it really look like. It is aligned with food industry needs - 4 of our business partner are interested in buying the SDF to implement into production of metallized packaging and process at their production plants. Feedback from the packaging and label market suggests the SDF will revolutionize packaging and label industry in Europe.

Keywords: packaging technologies,metallized film,demetallization,aluminum film,production of packaging and labels,packaging and labels proccessing,food safety,business plan,food waste,healthy food