Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Centre of ExcelleNce for nanophotonicS, advancEd Materials and novel crystal growth-Based technoLogiEs (ENSEMBLE3)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Germany,Italy,Spain,Poland,Poland
Call: Teaming Phase 2 (H2020-WIDESPREAD-2018-01, 2018)
Start date: 2019-10-01
End date: 2026-09-30
Duration (months): 84.0
Total project cost (EUR): 14999828.75
EU funding (EUR): 14999828.75
Participants: 10
Project status: SIGNED

The grand objective of the project is to create an autonomous Centre of Excellence ENSEMBLE3 with excellence in research and great innovation potential in the area of crystal growth-based technologies, novel functional materials with innovative electromagnetic properties, and applications in nanophotonics, optoelectronics, telecommunication, medicine and photovoltaics. The ENSEMBLE3 CoE will build on the best of (i) nanophotonics and medicine-oriented research of the University of Warsaw (UW); (ii) research and development in the area of crystal growth and innovation practices at the Institute of Electronic Materials Technology (ITME); and (iii) the technology transfers via existing companies and new spin-offs. ENSEMBLE3 will be a not-for-profit limited liability company acting as a scientific unit created in strong partnership with leading institutions in the field with complementary expertise: (i) the outstanding Karlsruhe Institute of Technology, Germany with its research excellence in controlling the flow of light at an unprecedented level utilizing three-dimensional structured materials; (ii) the Sapienza University of Rome, Italy with its research excellence in theory and experiment of linear and nonlinear optics, especially of complex materials; and (iii) the Cooperative Research Center nanoGUNE Consolider, Spain with its excellence in optical near-field nanospectroscopy and nanoscopy, nanomaterials and nanofabrication. The increase of scientific capabilities gained through the Teaming partnerships will enable ENSEMBLE3 to be successful in receiving competitive funding in international forums; achieving a measurable and significant improvement in terms of research and innovation culture; self-sustainability and sustained excellence provided by stable long-term agreements with the advanced partners; and help the Mazovian region and Poland to attain a competitive position in the global value chain. ENSEMBLE3 perfectly fits the goals outlined in Teaming Phase 2.

Keywords: crystal growth,advanced materials,functional materials,plasmonic materials,nanophotonics,metamaterials,special electromagnetic properties,structured materials,bottom up
AUTONOMOUS MULTI-ELECTRIC RECYCLING PROCESS LINE (MRP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-07-01
End date: 2021-06-30
Duration (months): 24.0
Total project cost (EUR): 2723904.5
EU funding (EUR): 1906733.15
Participants: 1
Project status: CLOSED

Metal recycling has not experienced any significant progress since blade-based systems were implemented. This system involves downtimes every 8 hours to sharpen the blades and blade´s replacement every 24 working hours, high maintenance costs and, in many cases, metal recovery rates that barely reach 70%. Guidetti is an Italian company with more than 30 years of experience providing solutions to the metal recycling sector. Thanks to the continuous feedback from our customers and the understanding of their needs, we have developed MRP: a new concept of metal recycling technology, that dispenses with the inefficient blades by high-durability hammers and centrifugal drums, that disintegrate the waste by collisions between waste particles, reaching recycling rates of 99 % with minimal wear on its components. MRP has been designed in the form of modules that overlap one another in tower-shape, decreasing the space requirements in the recycling facilities and also decreasing the energy consumption. MRP also incorporates a dust extraction system which avoids obstructions in the modules and reduces abrasion inside the drums and pipes. MRP, is not only a greater efficiency in terms of metal recovery but also in terms of maintenance (up to 10 times less maintenance costs), space requirements (MRP is a compact tower of 10x10x16(h)m), in personnel thanks to its fully automated process; saving in investment, being up to one third more economical requirement (only 2 operators need instead of 6-10). MRP points to be the benchmark of a market valued at more than € 220bn with a CAGR of 22%. The total investment needed to complete the project would be € 2.7million, which will be fast compensated according to our sales expectations. We have scheduled a start of MRP sales in 2021 and we have forecasted a 4-year ROI of 3.65 with € 15million of revenue and a total profit of € 5million.

Keywords: metal recycling,energy saving
Entailing Perpetuity: Family, Power, Identity. The Social Agency of a Corporate Body (Southern Europe, 14th-17th Centuries) (VINCULUM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Portugal
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-06-01
End date: 2024-11-30
Duration (months): 66.0
Total project cost (EUR): 1591450.0
EU funding (EUR): 1591450.0
Participants: 1
Project status: SIGNED

Few legal phenomena have been so relevant to premodern southern Europe societies as entails, a specific strategy that evolved to protect family inheritances, thus enabling the reproduction of elite social status. The VINCULUM project aims to explain how entailment became possible, how it functioned, and why it lasted for so many centuries. The project rests on the innovative theoretical claim that entails, as corporate bodies, functioned as a key social agent, created and acting within societies for which non-personal legal subjects were normal. Building on the Portuguese-Iberian case, and on the extensive research already carried out by me and my team, I propose to study 'entailment' as a diverse but pivotal practice, one embedded in law, aristocratic discourse, and kinship-based organization, and to carry out comprehensive analysis that explores this global nature. The research approach systematically breaks with traditional research frontiers: cases will extend from the 14th to 17th century in both continental and Atlantic spaces, and include both comparative perspectives and the study of later social reconfigurations. VINCULUM will be anchored in extended research in public archives and on unprecedented access to extensive private family archives, which have been opened to research by the ARQFAM program I have led since 2008. Data collection will allow for the construction of a large database, gathering all documents relating to each entail, under a theoretical model that seeks to reconstruct past information systems, thus testing a novel methodology developed in my previous research. The database that will gather c.7000 thousand entails, enabling systematic inquiries organized around the new conceptual definitions proposed by the project. The research will be strongly interdisciplinary, engaging with historical anthropology and archival science in order to construct a proper theoretical model for understanding this crucial legal and social phenomenon.

Keywords: history of premodern european institutions,history of the family,history of archives and sources epistemology,anthropological history
Quantum Optics with single flying electrons (FLYELEC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-04-01
End date: 2017-03-31
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

In quantum optics, a single photon source as well as a single photon detector is the elementary building block for the manipulation of information coded into a quantum state, a qubit. When combined with beam splitters, polarizers etc., photonic qubits can be manipulated to process quantum information. A well-known example is quantum cryptography, a secure way to transmit information. In analogy with photons, similar experiments should be possible with single flying electrons in a solid-state device. The advantage of performing quantum optics experiments with flying electrons is the existing Coulomb interactions between the electrons. Photons are basically non-interacting quantum particles and they therefore have a longer coherence time than electrons. However, due to the absence of interactions it is more difficult to construct a two-qubit gate, which operates at the single photon level. This represents a fundamental limitation to the development of quantum computation with photons. Recent experiments have now demonstrated that quantum optics with single flying electrons is in reach. Indeed, it has been shown that a single electron can be transferred on-demand between distant quantum dots. In these experiments, flying electrons have been transported by a sound wave and high fidelity for single electron emission as well as single electron detection has been demonstrated. This opens the possibility to perform quantum optics experiments with electrons in solid-state devices, which we aim to realize with this proposal. Due to the fact that electrons in solids are strongly interacting particles, new quantum entanglement schemes can be envisioned, not possible with photons.

Keywords: mesoscopic physics,quantum dots,nanoelectronics,single electron physics
Model-independent angular analysis of semileptonic B meson decays involving tau leptons (B2DTauNu)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2022-09-30
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: CLOSED

The project will characterise the physics of semileptonic b -> c tau nu quark transitions, by studying the angular properties of B -> D(*) tau nu meson decays. The branching fractions of B -> D(*) tau nu decays are measured to be larger than expected relative to their B -> D(*) mu nu counterparts, offering an intriguing hint of beyond the Standard Model (SM) physics in the form of lepton universality violation. Due to the spin structure of B -> D(*) tau nu decays, the full decay rate is described by a sum of twelve angular terms each with a corresponding coefficient. The values of these coefficients can be altered by New Physics (NP) operators such as charged Higgs bosons, Z' bosons, or leptoquarks, and measuring their values thus provides a powerful probe to search for deviations from the SM. The project will use LHCb Run 1 and 2 data to measure the B -> D(*) tau nu angular coefficients and signal yields in a model-independent manner, making use of novel binned template fit methods that fully account for resolution effects caused by the missing neutrino information. The measurements made will be a ground-breaking proof-of-principal, paving the way for high-precision angular coefficient measurements in future.

Keywords: angular analysis,flavour,leptoquark,r d,hadronic,model independent,new physics,standard model
The biofilm matrix and its functional role in the ecology of bacterial communities (BioMatrix)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Denmark
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 1978602.0
EU funding (EUR): 1978602.0
Participants: 1
Project status: SIGNED

Complex microbial communities are comprised of diverse, interacting species. Often, such interactions result in outcomes that cannot be predicted from studies of their individual components in isolation. However, the underlying mechanisms resulting in such community intrinsic properties remain unidentified. The overarching aim of BioMatrix is to identify the molecular mechanisms underpinning community intrinsic properties of bacterial communities. In nature, bacterial communities are predominantly organized as biofilms in which the cells are encased in a self-produced polymeric matrix. I hypothesize that the altered matrix composition of multispecies biofilms is the primary cause of community intrinsic properties defining bacterial communities. BioMatrix will test this hypothesis using expression studies of genes encoding matrix components and functional assessments of gene deletions leading to loss of specific matrix components. These will be addressed in settings of increasing environmental and community complexity, thus ensuring ecological relevance. High-resolution methodologies for single-cell detection will be combined with advanced image analysis to enable crucial micro-scale studies of bacterial communities. New approaches, such as printing 3D leaves suitable for manipulation and microscopy analysis, will be developed and applied to expand exploration to in situ conditions. BioMatrix will close a primary knowledge gap in microbial ecology, by identifying fundamental mechanisms shaping bacterial communities. The impact of these mechanisms for community function and protection will be validated in settings of high community and environmental complexity. This will theoretically and experimentally advance biofilm research, addressing a severe bias towards in vitro studies of model organisms. The fundamental findings of BioMatrix will be directly applicable in a variety of biotechnological industries depending on community activity, interaction and resilience.

Keywords: biofilm,multispecies biofilm,bacterial interactions,emergent behavior,microbial communities,soil,ecology,enzymatic activity,matrix formation,extracellular polymers,3d printing,metaproteomics
Exploiting the full integration potential of fluctuating renewable energies in power grid operation by new predictive technologies (FuturePowerFlow)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2019)
Start date: 2020-03-01
End date: 2022-02-28
Duration (months): 24.0
Total project cost (EUR): 2403750.0
EU funding (EUR): 1682625.0
Participants: 2
Project status: CLOSED

Over the past years, a lot of (political) initiatives led to rising numbers of decentralized renewable energy generators like wind parks and solar plants, even on rooftops of private households. Although this tendency is very positive concerning the targeted energy transition and for reaching the EU’s valuable 2030 climate and energy goals, the thousands of different decentralized power supply units connected in different parts of the grid, at different voltage levels and under different grid code standards challenge grid operators. The volatility of renewable energy generation (caused by weather conditions) and the need to balance power generation and demand within grids head to an oxymoron: although wind blows and sun shines, grid operators have to reactively curtail these plants from the grid to guarantee grid safety. Current control room systems are not made for a proactive and exact management and control of single assets – limiting the share of renewable energies in our power mix to a lower level than it’s possible. To fully exploit the potential of clean and green energy by 100%, energy & meteo systems developed FuturePowerFlow, an algorithm-based, modular system which uses weather forecasts, locations of renewable energy plants, data on grid infrastructure, historic demand data and even operating status of plants (iced, under maintenance, etc) to predict power flows in the grid based on generation and consumption for the next 48h in very high time-resolution. Instead of reacting just demand driven, FuturePowerFlow enables grid operators for the first time ever to proactively plan and manage the integration of decentralized renewable assets into their grid and execute precise actions within one system. FuturePowerFlow targets on a EUR 2.6bn energy market and is the perfect solution for transmission system operators and distribution system operators to manage their grids efficiently, directly targeting at and fulfilling their user needs.

Keywords: renewable energies,clean energy,green energy,energy transition,grid,power grid,software,platform
Predictive modelling of GPCR druggable allosteric sites (MIDAS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-11-01
End date: 2019-10-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

G protein coupled-receptors (GPCRs) are the most successful class of druggable targets in the human genome with an estimated 30 to 60 % of prescription drugs in European Union. GPCRs biological state can be modulated by small molecule ligands acting on spatially distinct allosteric binding sites (ABSs) that result more selective and less toxic than drugs binding to orthosteric sites. The discovery of lead compounds targeting ABSs is challenging and to date has largely been achieved through cost-intensive and time-consuming high-throughput screening. The recent release of X-ray structures of GPCRs in the complex with allosteric modulators opens new opportunities to develop structure-based computer aided methodologies to identify ABSs. MIDAS will aim to develop a computational methodology for the search of GPCR ABSs that will include cutting-edge enhanced sampling molecular dynamics simulation methods in cosolvent mapping. The action will solve several current limitations in cosolvent mapping: probe non-specific binding, protein denaturation, low probe sampling, and membrane distortion. MIDAS firstly develop the methodology in retrospective studies, aiming to identify ABSs in the M2, CRF1, P2Y and GCGR receptors for whom crystal structures complexed with allosteric modulators are available. The computational procedures will be developed for identification of extracellular and intracellular ABSs and ABSs at the interface between GPCR helices and lipids. Next, MIDAS will explore the developed protocols in prospective studies using the M3, µ-opipid and CCR5 receptors with available X-ray structures and known ligands. The action envisions the collaboration with experts from both academia and industry and is set to expand scientific, transferable and collaborative skills of the Experience Researcher. The outcome of the action will foster the development of novel health technologies for the discovery of safer drugs targeting membrane proteins.

Keywords: gpcr,molecular dynamics simulations,allosteric sites,probe mapping,cosolvent,drug design
Combatting Antimicrobial Resistance Training Network (CARTNET)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain,Italy,Belgium,Latvia,France,Netherlands,Netherlands,United Kingdom,Denmark,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-01-01
End date: 2021-12-31
Duration (months): 48.0
Total project cost (EUR): 3445596.72
EU funding (EUR): 3445596.7199999997
Participants: 12
Project status: CLOSED

CARTNET trains young researchers in Europe to address serious and global problems of antibiotic resistance. Disease-causing bacteria are becoming resistant even to last resort antibiotics and transmission of resistance genes and resistant pathogens is widespread between human, animal and environmental reservoirs. Therefore, CARTNET will focus on alternative approaches to handle antibiotic resistance and treating resistant infections in both humans and animals. It will provide competences to young researchers and future policymakers that will allow them to use knowledge at all relevant scientific levels and in collaboration with stakeholders in both human and veterinary medicine as well as in chemistry, structural biology and natural product chemistry to develop new antimicrobial solutions. CARTNET comprises researchers who are leading experts on antibiotic resistance and antimicrobial drug discovery. They will in cooperation with the recruited early stage research (ESR) trainees use structural biology to synthesize new antimicrobials, screen environmental microorganisms and microbiota for new active compounds and limit spread of resistance through knowledge of dissemination of mobile genetic elements. The research training is hosted by universities with a strong track record of graduate training and is composed of an ambitious scientific program flanked by essential generic training courses and with ample opportunity for networking at network meetings, conferences and shared secondments. In addition to training young researchers for the challenges of tomorrow CARTNET will from day one provide excellent research with impressive scientific and societal impact.

Keywords: antibiotic resistance,one health,antimicrobials,therapy,phage,plasmid