Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Database Analysis for Evaluation of Seismic Performance Assessment Tools (DatA ESPerT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-06-16
End date: 2019-06-30
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

In highly industrialised regions, earthquakes severely affect societies in terms of economic, social and environmental consequences due to the complex integrated and highly sensitive industries - even in areas of medium to low seismicity like Europe. Whereas the seismic behaviour of typical building structures is broadly understood and reflected in technical guidelines and damage prognosis tools worldwide, event reports and even assessment tools for industrial facilities are scarce, mainly because affected facilities are usually not generally accessible and are, thus, not covered by reconnaissance teams. After the 2012 Earthquake in the Italian Regione Emilia-Romagna (RE-R), however, the regional government gathered very detailed data on seismic damages to more than 3000 industrial / business facilities in order to distribute financial compensations. The data was collected in an extremely comprehensive database including – besides many other aspects – type, size and location of the business as well as damage to structures, components and stored goods and costs of reconstruction. Within the proposed DatA ESPerT project, the researcher will exploit this globally unique SFINGE-database in a rigorous way, in order to develop mathematical tools to assess the seismic performance of industrial facilities and to give damage prognoses for future earthquakes. Due to the comparable socio-economic context and similar seismic hazard levels, the research results will be valid for many regions in Southern Europe. Additional aspects of the project consider the development of cost/performance curves for seismic mitigation measures and the investigation of the geographical damage distribution in relation to the seismological circumstances in the Emilia-Romagna. The work is strongly supported by RWTH Aachen, by Munich RE reinsurance company and by RE-R who assured to the researcher within an official agreement access to the confidential SFINGE-database in the project's framework.

Keywords: earthquake engineering,probabilistic seismic performance assessment,consequence,functions for industrial facilities,earthquake database analysis,seismic retrofitting,cost,performance analysis
Cortical circuits underlying visual decision-making behaviors in mice (CORVISDEC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-08-01
End date: 2020-07-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

An important part of successfully navigating the world is the ability to make and act upon choices. In the brains of humans and other mammals, the cerebral cortex is considered an important structure for accumulating sensory evidence and executing actions, but the neural relationship between evidence and action is still unclear. A serial information processing hypothesis posits that cortical areas work in sequence to transform sensory evidence into behavioral choices, while an alternative parallel processing hypothesis argues that multiple, competing sensorimotor signals are combined at the earliest instance. Though there have been many studies of single-cell recordings offering support for one or the other hypothesis, the key to truly understand these complex behaviors will require recording from many hundreds of neurons over many different regions of the brain. In this proposal, I present a plan for a high-throughput assay of decision-making activity in the mouse brain. To compare these hypotheses, I will use two-photon calcium imaging to record simultaneously from thousands of neurons across many areas of cerebral cortex while mice perform a visually guided task that parses the perceptual, cognitive, and motor aspects of decision-making behavior. In analyzing the activity of these very large neural populations, I will be able to identify and distinguish how each cortical region contributes to aspects of the task and overall animal performance. I will further probe the structure of decision-making activity in cortex by introducing an adaptation paradigm to the same task, comparing how perceptual correlates for adaptation are linked to neural correlates, and observing how these effects manifest across different cortical areas. I will perform these experiments in the Cortical Processing Laboratory at University College London, led by Drs. Kenneth Harris and Matteo Carandini.

Keywords: vision,decision making,adaptation,cerebral cortex,cortical dynamics,two photon microscopy
Development and pilot production of SUStainable bio BINDer systems for wood based panels (SusBind)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Public-private partnerships
Destination: Bio-based Industries
Action type: Research and Innovation actions
Partnership: BBI (Art-187)
Countries involved: Germany,Austria,Germany,Austria,Germany,Spain,Germany,Austria,Sweden,Netherlands,Portugal
Call: Novel bio-based chemical precursors to improve the performance of mass consumption products (H2020-BBI-JTI-2017, 2017)
Start date: 2018-05-01
End date: 2022-08-31
Duration (months): 52.0
Total project cost (EUR): 5480220.0
EU funding (EUR): 4414418.75
Participants: 11
Project status: CLOSED

The overall objective of the SusBind project is to produce and test, in an industrially relevant environment (TRL5), bio-based binders as alternative to formaldehyde based binder currently used in the production of wood-based panel board (abbreviated as wood board). A lot has been done on this subject, but so far a bio-based binder able to compete at industrial scale with incumbent chemicals, does not exist. The reason to believe on the success of this project is backed: on the selection of the partners, which involves actors across the whole supply chain, and their extensive technological background developed during the last years. The SusBind project intends to build on these success factors by: i. Selecting more adequate feedstocks from existing European Bio-refineries; ii. Applying new and greener conversion technologies for the production of binders and intermediates, including novel epoxidizing enzymes (peroxygenases) developed in the project IndOx (FP7-KBBE; www.indoxproject.eu ); iii. Producing and validating these new bio-based binders with leading wood board manufacturers for two product types: P2 Particle Board (PB) and Medium Density Fibreboard (MDF) and; iv. Involving the world leading brand owner, producer and retailer of mass market furniture. The SusBind resulting binder system will prove better performance in PB and MDF in terms of 50 - 75% reduction of formaldehyde emissions than current fossil- and formaldehyde-based wood boards. The active participation of industry and a consumer brand owner secures post-project scale up into existing plants. On the basis of cost analyses performed, an economically viable and better performing precursor will increase the marketability of bio-based furniture products concerned. The results of SusBind will not only benefit consumer health and help mitigate climate change, but also strengthen the European furniture industry by providing a cost efficient, bio-based alternative to formaldehyde-based binders.

Keywords: bio precursor,bio based resins and binders,wood based panel boards,furniture
Hypothalamic mechanisms of thermal homeostasis and adaptation (Acclimatize)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-09-01
End date: 2025-02-28
Duration (months): 78.0
Total project cost (EUR): 1902500.0
EU funding (EUR): 1902500.0
Participants: 1
Project status: SIGNED

Mammalian organisms possess the remarkable ability to maintain internal body temperature (Tcore) within a narrow range close to 37°C despite wide environmental temperature variations. The brain’s neural “thermostat” is made up by central circuits in the hypothalamic preoptic area (POA), which orchestrate peripheral thermoregulatory responses to maintain Tcore. Thermogenesis requires metabolic fuel, suggesting intricate connections between the thermoregulatory centre and hypothalamic circuits controlling energy balance. How the POA detects and integrates temperature and metabolic information to achieve thermal balance is largely unknown. A major question is whether this circuitry could be harnessed therapeutically to treat obesity. We have recently identified the first known molecular temperature sensor in thermoregulatory neurons of the POA, transient receptor potential melastatin 2 (TRPM2), a thermo-sensitive ion channel. I aim to use TRPM2 as a molecular marker to gain access to and probe the function of thermoregulatory neurons in vivo. I propose a multidisciplinary approach, combining local, in vivo POA temperature stimulation with optogenetic circuit-mapping to uncover the molecular and cellular logic of the hypothalamic thermoregulatory centre and to assess its medical potential to counteract metabolic syndrome. Acclimation is a beneficial adaptive process that fortifies thermal responses upon environmental temperature challenges. Thermoregulatory neuron plasticity is thought to mediate acclimation. Conversely, maladaptive thermoregulatory changes affect obesity. The cell-type-specific neuronal plasticity mechanisms underlying these changes within the POA, however, are unknown. Using ex-vivo slice electrophysiology and in vivo imaging, I propose to characterize acclimation- and obesity-induced plasticity of thermoregulatory neurons. Ultimately, I aim to manipulate thermoregulatory neuron plasticity to test its potential counter-balancing effect on obesity.

Keywords: trp ion channels,hypothalamus,thermoregulation,neuronal circuit,neuronal plasticity,temperature detection,core body temperature,energy expenditure,metabolic syndrome,obesity,leptin
Returning to a Better Place: The (Re)assessment of the ‘Good Life’ in Times of Crisis (BETLIV)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Switzerland
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-02-01
End date: 2023-07-31
Duration (months): 66.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

What makes for a valuable and good life is a question that many people in the contemporary world ask themselves, yet it is one that social science research has seldom addressed. Only recently have scholars started undertaking inductive comparative research on different notions of the ‘good life’, highlighting socio-cultural variations and calling for a better understanding of the different imaginaries, aspirations and values that guide people in their quest for better living conditions. Research is still lacking, however, on how people themselves evaluate, compare, and put into perspective different visions of good living and their socio-cultural anchorage. This project addresses such questions from an anthropological perspective, proposing an innovative study of how ideals of the good life are articulated, (re)assessed, and related to specific places and contexts as a result of the experience of crisis and migration. The case studies chosen to operationalize these lines of enquiry focus on the phenomenon of return migration, and consist in an analysis of the imaginaries and experience of return by Ecuadorian and Cuban men and women who migrated to Spain, are dissatisfied with their life there, and envisage/carry out the project of going back to their countries of origin (Ecuador and Cuba respectively). The project’s ambition is to bring together and contribute to three main scholarly areas of enquiry: 1) the study of morality, ethics and what counts as ‘good life’, 2) the study of the field of economic practice, its definition, value regimes, and ‘crises’, and 3) the study of migratory aspirations, projects, and trajectories. A multi-sited endeavour, the research is designed in three subprojects carried out in Spain (PhD student), Ecuador (Post-Doc), and Cuba (PI), in which ethnographic methods will be used to provide the first empirically grounded study of the links between notions and experiences of crisis, return migration, and the (re)assessment of good living.
Eating patterns in pregnancy: unraveling the underlying neurocircuits and its deleterious metabolic consequences (NEUROPREG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-03-01
End date: 2023-02-28
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 2
Project status: CLOSED

Pregnancy entails remarkable whole-body biological adaptations. Extensive evidence in humans shows significant alterations in taste perception and nutrient preference throughout pregnancy, resulting in frequent food cravings with a recurrent search for high-caloric, high-palatable foods. However, the underlying neurocircuits implicated in specific pregnancy-related eating disturbances are still unknown. In line with that, the project hypothesizes that pregnancy modifies the neuroconnectome of critical brain regions implicated in taste and ingestive behavior, altering maternal dietary preferences and habits favoring the consumption of high-palatable food. The persistence of abnormal dietary patterns, in the prevailing western life-style, may underlie serious detrimental metabolic and neuropsychological outcomes in both mothers and offspring that often lead to eating disorders and obesity vulnerability. The project aims to use a combination of cutting-edge methodologies in the mouse, including behavioral, whole-brain imaging, chemogenetics, and fiber photometry to establish the genetic and neurocircuits underlying pregnancy-related eating behaviors and its effects on offspring's metabolic health. The present proposal will provide novel insights on the link between specific physiological conditions (gestation), feeding neurocircuits and behavior as well as transgenerational metabolic and neuropsychological impact, unraveling new preventive strategies (nutritional and healthier lifestyle) to control the rising incidences of “food addiction”, disturbed eating patterns, and obesity predisposition. Ultimately, the knowledge generated by NEUROPREG can reduce overall costs in obesity and related disorders, that consumes more than $1.2 trillion of the global health system every year. My outstanding scientific experience in neuroscience and maternal influences on offspring metabolic outcomes make me the ideal candidate to develop this MSCA.

Keywords: eating patterns,pregnancy,neuroscience,metabolism,programming,offspring,obesity
Narrowband IoT for Waste Collection in Rural Areas (NB4WASTE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Spain
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-08-01
End date: 2017-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The NB4WASTE Project, developed by SYLTEC, will put on the market an integral IoT solution for municipal waste collection management in rural areas using the new NB-IoT communication standard, for the first time in this type of market, including a specific developed low cost unit ultrasonic sensor technology with low energy consumption and 10 years battery life. Thanks to NB4WASTE solution municipalities will increase yield and profit per service (30%) and will save on fuel costs (25%). Additionally waste bin companies business will increase by 40% offering the NB4WASTE solution. Exploitation of Big Data obtained by means of the NB4WASTE in order to decrease operating costs will be one of the main objectives. Thus, by route optimization and predictive operations thanks to Big Data exploiting will result in 25-50% costs and 25% CO2 savings. The main alternatives to NB-IoT as competitive solutions available on the market of Low Power Wide Area technologies are LoRa and SigFox but both of them are worse considering market flexibility implementation and coverage. Only NB-IoT ensures business scalability expansion and reliable service. If we add market flexibility (open standards) and coverage (spectrum efficiency) to the main properties scored by experts (low power, bandwidth, supplier breadth, security and deployments) it is the most competitive alternative. NB4WASTE will contribute to Circular Economy by increasing recycling targets due to more optimized selective collection implementation for smart waste management in rural areas. It will also promote competitive rural business and help European Members for digital inclusion ensuring that everybody can contribute to and benefit from the digital economy and society. Financial 5 years forecast demonstrates NB4WASTE profitability. With a margin of 20% and a total of 418 units sold during 2019-2023 period (20% market penetration: France, Italy, Spain, UK and Chile) the Return of Investment for SYLTEC will be around 3,84

Keywords: waste collection,waste management,waste bin,waste container,municipal waste,rural areas,nb iot,lpwan,smart cities,smart bin,ultrasonic sensor,circular economy,rural development
Many-Body Physics with Driven Open Quantum Systems of Atoms, Light and Solids (DOQS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2016-02-01
End date: 2022-07-31
Duration (months): 78.0
Total project cost (EUR): 1676423.75
EU funding (EUR): 1676423.75
Participants: 1
Project status: CLOSED

Understanding the quantum many-particle problem is one of the grand challenges of modern physics. While tremendous progresses have been made over the past decades in thermodynamic equilibrium, nonequilibrium many-body quantum physics is still in its infancy. Strong motivation for addressing this challenge comes from recent experimental developments in diverse areas, ranging from cold atomic gases over light-driven semiconductors to microcavity arrays. This moves systems into the focus, which are located on the interface of quantum optics, many-body physics and statistical mechanics. They share in common that coherent and driven-dissipative quantum dynamics occur on an equal footing, creating scenarios without immediate counterpart in traditional condensed matter systems. This project has the goal of pushing forward the understanding of such driven open quantum systems. To this end, we follow a combined approach structured around three key challenges. (i) We aim to identify novel macroscopic phenomena, which manifestly witness microscopic non-equilibrium conditions. This concerns non-thermal stationary states, where we will shape an understanding of non-equilibrium phase diagrams and the associated phase transitions, in particular constructing a notion of driven quantum criticality. But it also encompasses the identification of new universal regimes in open system time evolution. Finally, we will extend the concept of topological order to a broader non-equilibrium context, motivated by quantum information applications. (ii) We will create new theoretical tools, in particular advancing a flexible Keldysh dynamical quantum field theory for driven open quantum systems. (iii) We will address a broad spectrum of cutting edge experimental platforms in view of exploring our theoretical scenarios, and to foster mutual cross-fertilization. With an emphasis on cold atomic gases, this program also comprises exciton-polariton condensates and coupled circuit QED architectures.

Keywords: non equilibrium many body physics,macroscopic quantum phenomena,phase transitions