Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
an Innovative Negative Ion TIme projection chamber for Underground dark Matter searches (INITIUM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Italy,Italy
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-03-01
End date: 2025-02-28
Duration (months): 72.0
Total project cost (EUR): 1995719.0
EU funding (EUR): 1109705.0
Participants: 2
Project status: SIGNED

INITIUM: an Innovative Negative Ion TIme projection chamber for Underground dark Matter searches. INITIUM goal is to boost the advancement of gaseous Time Projection Chamber detectors in the Dark Matter (DM) searches field, one of the most compelling issues of todays fundamental physics. I believe this approach to be superior because of its active neutron/electron discrimination, directional and fiducialization capability down to low energies and versatility in terms of target material. Thanks to recent advances in Micro Pattern Gas Detectors amplification and improved readout techniques, TPCs are nowadays mature detectors to aim at developing a ton-scale experiment. INITIUM focuses on the development and operation of the first 1 m3 Negative Ion TPC with Gas Electron Multipliers amplification and optical readout with CMOS-based cameras and PMTs for directional DM searches at Laboratori Nazionali del Gran Sasso (LNGS). INITIUM will put new significant constraints in a DM WIMP-nucleon scattering parameter space still unexplored to these days, with a remarkable sensitivity down to 10-42-10-43 cm2 for Spin Independent coupling in the 1-10 GeV WIMP mass region. As a by-product, INITIUM will also precisely and simultaneously measure environmental fast and thermal neutron flux at LNGS, supplying crucial information for any present and future experiment in this location. Consequently, I will demonstrate the proof-of-principle and scalability of INITIUM approach towards the development of a ton-scale detector in the context of CYGNUS, an international collaboration (of which I am one of the Spokespersons and PIs) recently gathered together with the aim to establish a Galactic Directional Recoil Observatory, that can test the DM hypothesis beyond the Neutrino Floor and measure the coherent scatter of galactic neutrinos, generating a significant long-term impact on detection techniques for rare events searches.

Keywords: directional dark matter searches,time projection chamber,negative ion drift,gas electron multipliers gems,cmos based camera
VIrus and BacteRia In Oral Disease: the EBV model in periodontitis (VIBRiOD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-05-01
End date: 2022-04-30
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

Periodontal disease, conditions that affect the structures surrounding the teeth, is the most common disease of mankind (listed #1 in 2001 Guinness World Records). The total economic impact of periodontal disease represents the major component of the $442 billion direct and indirect expenditures of oral diseases incurred worldwide in 2010. Periodontal disease can lead to tooth loss, causing aesthetic effect as well as affecting chewing and speech. Beyond oral health, it is associated with systemic diseases and even with cancer risk. Obviously, periodontitis represents a major global health problem with significant social and economic impact. Development of effective therapies, therefore, requires deeper insights into the etiopathogenesis of the periodontal disease. The focus has traditionally been that pathogenesis occurs when the balance between the oral microbial biofilm and the host is lost, owing to dysbiosis and immune overreaction of the host to microbial presence. However, bacterial-host interaction alone does not adequately explain the clinical features of the disease. Recently, a new paradigm was proposed in pathogenesis involving a viral and bacterial combination to promote long-term chronic inflammatory disease. The project VIBRiOD will be focused on the etiopathogenesis of periodontitis based on Epstein-Barr virus (EBV)–pathogenic bacterial biofilm–human immunity response synergies. Specifically, the VIBRiOD aims to understand 1) EBV behaviour during periodontitis and relationship to dysbiosis, 2) bidirectional interaction of dysbiosis and EBV activation, 3) tridirectional relationship of dysbiosis, EBV activation and host immune response. The multidisciplinary nature of the project is strong, involving a combination of classic to modern approaches of microbiology, molecular biology, immunology and virology. The results have the potential to contribute to the advancement of periodontitis research and ultimate control of the disease.

Keywords: epstein barr virus ebv,bacterial pathogens,periodontitis,ebv bacteria synergy
RESEARCH ON EFFICIENT INTEGRATED SYSTEMS FOR THE MANUFACTURING OF COMPLEX PARTS BASED ON UNIDIRECTIONAL TAPES FOR THE AUTOMOTIVE AND AERONAUTICAL (FORTAPE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Technologies for Factories of the Future
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Spain,Germany,Italy,Spain,Poland,France,France,France
Call: Manufacturing processes for complex structures and geometries with efficient use of material (H2020-FoF-2014, 2014)
Start date: 2015-02-01
End date: 2018-01-31
Duration (months): 36.0
Total project cost (EUR): 5030003.96
EU funding (EUR): 5030003.96
Participants: 11
Project status: CLOSED

More and more industrial sectors are demanding high performance composite materials to face new challenges demanded by the transport sector. Carbon and glass fibre unidirectional continuous tape reinforced composites are one of the most promising options. It would be reasonable to expect that the manufacturing methods to obtain composite parts made of this hybrid material will be capable to tailor-made and optimize even more the advantageous properties given by the tapes nature. However, at the moment, these technologies are not mature enough for a full industrial implementation. Main existing barriers are related to the high consumption of resources, lower rates of automation, high production of defective and the subsequent growth of the manufacturing costs. FORTAPE aims to solve these drawbacks through the development of an efficient and optimized integrated system for the manufacturing of complex parts based on unidirectional fibre tapes for its application in the automotive and aeronautical industry, with the minimum use of materials and energy. To achieve this objective, three main routes for fibre impregnation will be researched to manufacture the unidirectional carbon and glass fibre tapes: novel heating up technologies, melted supercritical fluid-aided thermoplastic polymers and fluidized bed of powders. Novel combination of process-machine approaches will be applied in overmoulding and in-situ consolidation to manufacture the composite parts for the targeted sectors. Novel mathematical modelling and computational simulation concepts will be developed to support the structural optimization and the failure prevention and new instrumentation strategies for process control will be implemented for the selection of the best process. The FORTAPE consortium, led by CTAG, gathers 10 partners from 5 different European countries, and covers the whole value chain needed to develop new composite technologies with efficient use of materials and energy.

Keywords: composite manufacturing,automotive,aeronautic,energy and material efficiency,ud tapes,carbon fibre,glass fibre,overmoulding,in situ consolidation,mathematical modelling,computational simulat
Arqus Research and Innovation (Arqus R.I.)

Framework: Horizon 2020 — Science with and for Society
Action type: Coordination and support actions
Countries involved: Austria,Germany,Italy,Spain,Norway,Lithuania,France
Call: Support for the Research and Innovation Dimension of European Universities (Part I) (H2020-IBA-SwafS-Support-1-2020, 2020)
Start date: 2021-01-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 8
Project status: SIGNED

The Arqus European University Alliance brings together seven longstanding prestigious comprehensive research-intensive universities who share extensive experience in joint projects and a similar profile as internationalized institutions with deep regional engagement. Through this project, Arqus aims to enhance the research and innovation dimension of the Alliance’s activities and to address current global societal challenges through intensified joint research characterised by the pursuit of excellence, openness, transparency and effective engagement with society. Based on analysis of existing strengths, prior cooperation and shared strategic research interests, the Alliance will focus on the fields of Artificial Intelligence/Digital Transformation and Green Deal/Climate Change as transversal priority areas for enhanced research collaboration, characterised by their interdisciplinarity. The project is organised around three major challenges, all intended to foster a context to nurture sustainable strengthened collaboration. The first addresses Joint Science and Innovation, through building an Arqus research community, and designing a roadmap for transformation(al) excellence. The second centres on New Perspectives on Research, seeking to strengthen human capital through alternative approaches to assessment and recognition, and to re-thinking transfer, with special reference to the Social Sciences, Humanities and the Arts. The third, Open to Society, focusses on the culture change brought by Open and Citizen Science. Arqus Research & Innovation aims to complement and build on efforts already underway to foster scientific cooperation within the European University consortium, and to seek synergies between the education, research and innovation dimensions of Arqus.

Keywords: european universities,pilot,transformation agenda,research and innovation
FruitWatcher: Monitoring traceability assessment for fresh products transport conditionsWatcher: Monitoring traceability assessment for fresh products transport conditions (FruitWatcher)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: Spain
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-1-2015, 2015)
Start date: 2016-02-01
End date: 2016-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Currently, fruits and fresh vegetables production and stores are under severe control conditions, including expensive installations of controlled atmosphere environments with ozone injectors, gases stratification control and other devices for ensuring best conditions. Nevertheless, there is a lack of control from stores until distributors' facilities (or other stores), and products use to suffer undesired ripeness, resulting on monetary and resources losses. Moreover, far locations customers apply major discounts by affirming that excessive spoilage or ripeness took place along transport, leaving producers in a defenceless state. Our device provides all transport conditions data in order to ensure the traceability of the whole transport of fruit and fresh vegetables in transport linking them to GPS positioning. We take advantage of our expertise in monitoring devices related to energy efficiency, transport and industrial processes in order to fulfill fruit producers' needs of vehicles positioning linked data, providing best conditions monitoring along transport and assessing whole life cycle control, even detecting possible recurrent undesired events. The most important stage for us to realize that the project may be feasible was the contact with potential customers and the changes (pivots) we designed in our business model. So, we decided to go for it, launching initial testing with customers and reaching first sales and investors/commercial partners interest Main pivots included setting monthly subscription as main revenue, leaving gases measurement as optional feature and pointing not only at fruit distributors but also at transport companies as our potential customers. All required tasks for project adequate management have been analyzed, as well as their requirements in terms of resources (human or economic), duration, overlappings, risks, etc. We count on GEEZAR current staff and we foresee the recruitment of up to four people for design and commercial tasks.

Keywords: internet of things,fiware,traceability,transparency
Beyond Static Molecules: Modeling Quantum Fluctuations in Complex Molecular Environments (BeStMo)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Luxembourg
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-03-01
End date: 2022-08-31
Duration (months): 66.0
Total project cost (EUR): 1811650.0
EU funding (EUR): 1811650.0
Participants: 1
Project status: CLOSED

We propose focused theory developments and applications, which aim to substantially advance our ability to model and understand the behavior of molecules in complex environments. From a large repertoire of possible environments, we have chosen to concentrate on experimentally-relevant situations, including molecular fluctuations in electric and optical fields, disordered molecular crystals, solvated (bio)molecules, and molecular interactions at/through low-dimensional nanostructures. A challenging aspect of modeling such realistic environments is that both molecular electronic and nuclear fluctuations have to be treated efficiently at a robust quantum-mechanical level of theory for systems with 1000s of atoms. In contrast, the current state of the art in the modeling of complex molecular systems typically consists of Newtonian molecular dynamics employing classical force fields. We will develop radically new approaches for electronic and nuclear fluctuations that unify concepts and merge techniques from quantum-mechanical many-body Hamiltonians, statistical mechanics, density-functional theory, and machine learning. Our developments will be benchmarked using experimental measurements with terahertz (THz) spectroscopy, atomic-force and scanning tunneling microscopy (AFM/STM), time-of-flight (TOF) measurements, and molecular interferometry. Our final goal is to bridge the accuracy of quantum mechanics with the efficiency of force fields, enabling large-scale predictive quantum molecular dynamics simulations for complex systems containing 1000s of atoms, and leading to novel conceptual insights into quantum-mechanical fluctuations in large molecular systems. The project goes well beyond the presently possible applications and once successful will pave the road towards having a suite of first-principles-based modeling tools for a wide range of realistic materials, such as biomolecules, nanostructures, disordered solids, and organic/inorganic interfaces.

Keywords: quantum fluctuations,molecular environments,complex systems
Characterizing the Occipital Oscillatory Activity in Blindness (COcOAB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-04-01
End date: 2018-03-31
Duration (months): 24.0
Total project cost (EUR): 168277.2
EU funding (EUR): 168277.2
Participants: 1
Project status: CLOSED

The massive reorganization of the occipital regions as a consequence of lack of vision represents one of the most remarkable examples of the plastic potentialities of the human brain. Despite the large amount of neuroimaging evidence proving the involvement of occipital areas of blind individuals in non‐visual input processing, the functional role of this sensory reorganized region is still matter of intense debate. In COcOAB, we will use an underexploited neuroimaging technique in this field, magnetoencephalography (MEG), in order to study the oscillatory profile of ensembles of occipital neurons and their brain‐wide functional interaction patterns in blind individuals. This will allow us to gather unprecedented information about the functional relevance of non‐visual activity in the occipital cortex of blind individuals. Moreover, COcOAB will assess the impact of age onset and duration of visual deprivation on the occipital oscillatory activity, thus providing insights into the relationship between blindness and sensitive periods of maturation in the visual system. The groundbreaking potentials of COcOAB reside in the application of the MEG technique to the study of two experimental domains — sensory illusions and stimulation at threshold — that has been so far neglected in the field of sensory deprivation. COcOAB represents a unique testing ground to address how specific regions support perception in a mechanistic fashion in visually deprived individuals, thus challenging the current knowledge on the functionality of these reorganized regions via a highly innovative approach.

Keywords: crossmodal plasticity,blindness,multisensory integration,magnetoencephalography
pREVention and management tools for rEducing antibiotic Resistance in high prevalence Settings (REVERSE)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Preventing disease
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Spain,Spain,Spain,Spain,Israel,Switzerland,Greece,Romania,Switzerland,Netherlands,United Kingdom,United Kingdom
Call: New approaches for clinical management and prevention of resistant bacterial infections in high prevalence settings (H2020-SC1-2020-Single-Stage-RTD, 2020)
Start date: 2021-07-01
End date: 2026-06-30
Duration (months): 60.0
Total project cost (EUR): 13953194.98
EU funding (EUR): 13953194.98
Participants: 16
Project status: SIGNED

Emerging antibiotic resistance has become an endemic problem, slowly increasing under the radar and depriving future generations of effective therapies. The goal of REVERSE is to develop and implement cost-effective strategies and tools for the prevention and clinical management of healthcare-associated infections due to multidrug-resistant pathogens, and to reduce the burden of antimicrobial resistance in high prevalence healthcare settings. To achieve these goals, REVERSE will use a mixed-methods approach combining quantitative research with implementation science and economic analysis. The aim is to produce results that go beyond the evidence-base we have today. REVERSE will answer the question about real-life effectiveness of infection prevention and control programmes in combination with antibiotic stewardship on healthcare-associated infections due to multidrug-resistant microorganisms. It will offer implementation strategies to the participating hospitals but also study the effectiveness of external implementation support in a hybrid implementation-effectiveness trial. REVERSE will develop a novel health-economic framework that allows for incorporating of effect of changes in the use of a range of antibiotics on antibiotic resistant infections, and estimating long-term population effects, to integrate both into cost-effectiveness analyses. It will be able to conclude on effectiveness and applicability of prevention strategies in lower-resource settings by cross-checking its programmes with activities in low-and-middle income countries. Four European countries will have a platform of highly experienced hospitals to build on and expand a national network for combatting antibiotic resistance. REVERSE will produce tools and bundles on infection prevention and control, antibiotic stewardship and implementation support. Massive online open courses and other dissemination strategies will make the findings of REVERSE accessible to a wide range of stakeholders.

Keywords: antimicrobial resistance,infection prevention and control,antibiotic stewardship,cost effectiveness,healthcare associated infections
DEmonstration of concentrated SOLar power coupled wIth advaNced desAlinaTion system in the gulf regION. (DESOLINATION)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Innovation actions
Countries involved: Oman,Italy,Saudi Arabia,Spain,Italy,Germany,Spain,Germany,Italy,Finland,Slovenia,Sweden,Sweden,France,France,Netherlands,United Kingdom,United Kingdom,United Kingdom,Bahrain,Denmark
Call: Efficient combination of Concentrated Solar Power and desalination (with particular focus on the Gulf Cooperation Council (GCC) region) (H2020-LC-SC3-2020-NZE-RES-CC, 2020)
Start date: 2021-06-01
End date: 2026-09-30
Duration (months): 64.0
Total project cost (EUR): 13826780.07
EU funding (EUR): 9995214.75
Participants: 22
Project status: SIGNED

The DESOLINATION project aims to couple efficiently the low grade wasted heat of two different CSP cycles to an innovative desalination system based on forward osmosis. Indeed, the demonstration in Saudi Arabia already hosts a 100kWe air Bryton cycle that will be coupled with the innovative forward osmosis desalination system developed in DESOLINATION. Moreover, to take into account the future and most efficient cycles, a 1MWe CO2 blends power cycle will be installed on site and demonstrated alongside the existing power plant. More than 2300 hours of testing are planed on site to assess the CSP and desalination technologies and optimise their efficiencies. DESOLINATION will thus provide solutions to be integrated in existing CSP plants across the region as well as an innovative more efficient coupling with a tailored made power cycle for more efficient and cost effective new CSP plants based on CO2 blends. Gathering 10 EU research centres or academic profiles, 6 EU companies with a deep knowledge of the market, and 4 academic partners from the GCC countries, DESOLINATION offers a balanced and high international level consortium, with excellent research capacities and a strong market uptake potential. DESOLINATION indeed aims to have market competitive solutions showing the potential for high wasted-heat-to-freshwater conversion efficiency as well as high CSP power efficiency (>42% at 550°C) leading to an LCOE below 90€/MWh and LCOW below 0.9€/m3 when scaled-up at 100MW scale. The reduction of CO2 emissions per cubic meter of water desalinated would be up to 70% compared to existing desalination systems. Moreover, brine rejection being a key environmental issue, DESOLINATION will also focus on developing solutions to decrease brine rejection by up to 80%. Through the developments of the CSP+D system and its demonstration in a real environment, DESOLINATION will foster the use of solar energy for desalination in the EU, in the GCC countries, and the rest of the world.

Keywords: desalination,supercritical co2,co2 blends,forward osmosis,membrane distillation,draw solution