Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Untapping the potential for improved female reproductive healthcare: diagnosing and reinforcing the status of UTERINE-associated fertility (TULIP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden,Netherlands,Ireland,Estonia,Spain,Greece
Call: MSCA Staff Exchanges 2024 (HORIZON-MSCA-2024-SE-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 1945311.43
EU funding (EUR): 1803600.0
Participants: 12
Project status: SIGNED

Conception and pregnancy are both complex processes, with approximately 1 in 6 women worldwide experiencing infertility, often due to compromised uterine function, the organ designed solely for sustaining life. However, these dysfunctional uterine mechanisms remain not fully understood. Moreover, assisted reproduction technologies (ART) are employed to address infertility, with 5% of newborns in Europe conceived through ART. Nevertheless, the use of ART still results in low pregnancy success rates, with uterine dysfunction being a significant factor. This underscores the importance of the uterus in medical research, which has previously received little attention for its pivotal role in the journey towards motherhood. The TULIP consortium focuses on emerging topics, including the interplay between glycosylation and the microbiota within the uterus in relation to fertility. This interdisciplinary consortium comprises experts from six European countries, representing eight academic and four industry partners, and uniquely combines specialists in female reproductive medicine with researchers in glycobiology, microbiota studies, genomics, and data science. We aim to achieve a breakthrough in understanding the core biological aspects of conception, thereby fostering accurate and less invasive diagnostic methods that lead to more effective and personalised implementation of ART through pioneering tools designed to overcome poor reproductive outcomes. This breakthrough will be achieved by engaging 33 early-stage researchers in a collaborative interdisciplinary training and research programme. The programme seeks to emphasise scientific knowledge while fostering entrepreneurial and transferable skills over the 48-month project period. Collectively, these efforts enhance diagnostic and therapeutic tools to improve reproductive success in both natural and assisted conception while reinforcing inter-sectoral and interdisciplinary collaborative networks and the R&I capacity.

Keywords: female reproduction,infertility,assisted reproduction,uterus,endometriosis
Self-assembled 2D Chiral Plasmene Nanosheets for Biomarker Detection Based on Surface-Enhanced Raman Scattering (ChirPlasBiosensing)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-11-01
End date: 2025-10-31
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 3
Project status: SIGNED

In this project, I will develop chemical methods to synthesize colloidal chiral plasmonic nanoparticles and assemble them into 2D plasmene nanosheets. Chiral components on the surface of metal nanocrystals enantioselectively interact with chiral growth-directing molecules, such as amino acids and peptides, leading to the asymmetric evolution of chiral plasmonic metal nanoparticles. The chirality transfer from soft chiral molecules to inorganic metal surfaces derive from the highly twisted surface features on the nanoparticles induced by the chiral molecules during overgrowth. I will synthesize chiral plasmonic nanoparticles with different morphologies, finely tune the twisted surface elements, adjust their interparticle spacings and orientation, and optimize their chiroptical responses. Highly chiral 2D graphene-like plasmonic superlattices, or “plasmene nanosheets”, will then be fabricated on flexible substrates to serve as all-hot-spot practical chiral sensing platforms via control over interparticle spacing and orientation. A novel functional chiral plasmonic biosensing platform will be constructed by the self-assembled 2D chiral plasmene nanosheets, based on surface-enhanced Raman scattering, for ultrasensitive biomarker detection and chirality discrimination.

Keywords: chiral plasmonics,circular dichroism,surface enhanced raman scattering,biomarker detection
Improve Interconnected innovation ecosystems supporting Actions for Citizen awareness and Twin Transition in the entire cosmetic value chain (ACTT4Cosmetics)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Interconnected Innovation Ecosystems
Destination: Interconnected Innovation Ecosystems
Action type: COFUND actions
Countries involved: France,Italy,Portugal,Poland,Ukraine,Romania
Call: Implementing co-funded action plans for interconnection of innovation ecosystems (HORIZON-EIE-2022-CONNECT-02, 2022)
Start date: 2023-05-01
End date: 2028-04-30
Duration (months): 60.0
Total project cost (EUR): 3611272.24
EU funding (EUR): 1805636.14
Participants: 10
Project status: SIGNED

ACTT4Cosmetics aims at fostering the creation of a more efficient, open, inclusive, and interconnected innovation ecosystem in the field of cosmetics across Europe by drawing on the strengths of existing ecosystems and by pulling in new, less well-represented stakeholders and less advanced innovation territories. By implementing joint activities (between R&I actors, public authorities, and the private sector) towards innovation deployment, ACTT4Cosmetics aims to integrate the entire value chain of the cosmetic industry to implement structural changes such as digital and ecological transitions, but also innovation as a lever for sustainable growth to respond to the main local and EU challenges in the field of cosmetics for the benefit of the society. To improve the digital and sustainability maturity and to find innovative sustainable solutions, the consortium will use ACTT4Cosmetics to inform the stakeholders, train the entire ecosystem through capacity building actions, boost sectorial and cross sectorial collaborations and share funding opportunities. ACTT4Cosmetics has 3 ambitious general objectives in line with the HORIZON-EIE-2022-CONNECT-02 call expectations: (i) Innovation deployment through digital transition in the Cosmetic sector, (ii) Reinforcing Green Transition in the cosmetic sector in order to fight climate change, (iii) Create consumer/citizen awareness of, implication in, and sensibilization on cosmetic industry. ACTT4Cosmetics gathers 8 partners and 2 associated partners from 6 countries. The partners are very complementary as they have both common assets and separate key competences. An implementation plan is presented in the form of 7 work packages. Synergy in communication and dissemination by the partners and stakeholders will permit to maximize the ACTT4Cosmetics project impact. Solutions to overcome the fundamental barriers by creating an open, inclusive, efficient cosmetic ecosystem to go towards Digital, Green and Societal Transition all over Europe.

Keywords: cosmetics,digital transition,green transition
Medical Electricity, Embodied Experiences, and Knowledge Construction in Europe and the Atlantic World, c.1740-1840 (ELBOW)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Finland
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1499775.0
EU funding (EUR): 1499775.0
Participants: 1
Project status: SIGNED

Scientific knowledge has long been understood to be subjective and situated. ELBOW examines this situatedness from a previously unexplored historical viewpoint by investigating the role of lay embodied experiences in eighteenth-century scientific knowledge construction. The project starts from the premise that knowledge is necessarily filtered through individuals’ embodied cognition and therefore tactile, sensory, and experiential. Using eighteenth-century medical electricity as an empirical case study, the project analyses how patients’ embodied and experiential knowledge influenced the medical knowledge emerging from electrotherapies, as well as whose experiences and ways of knowing ended up contributing to scientific knowledge. As a novel experimental therapy, medical electricity provides an exceptional window into practices of knowledge construction, authorisation, and marginalisation. Since electrical treatments and the bodily sensations they created were meticulously recorded by doctors and patients alike, these descriptions can be analysed as repositories of experiences and understandings of embodiment as well as epistemological beliefs regarding body, life, and matter. Medical electricity offers the perfect vantage point for examining popular epistemological understandings, their interaction with scientific epistemologies, and the way they manifested themselves in electrotherapeutic practices. ELBOW devises an innovative methodological approach to tease out patients’ embodied experiences and epistemological beliefs from a variety of sources, including scientific treatises, doctors’ casebooks, advertisements, fiction, and ego-documents. Combining phenomenology and cognitive science with history of medicine methods, the project proposes a new, theoretically sophisticated approach to analysing historical everyday experiences and embodied knowledge—and thereby a turn towards a new experiential paradigm in history of knowledge.

Keywords: medical electricity,history of knowledge,gender and embodiment,eighteenth century europe and atlantic world
Solar-Driven Photocatalytic CO2 Reduction by Layered Double Hydroxide Coated Biomass-Derived Carbon: Materials to Reactor Scale up (SOLCORL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Carbon dioxide (CO2), the principal greenhouse gas, exacerbates global warming and climate change, presenting significant challenges to human health, economic stability, and environmental sustainability. In response to the urgent 2030 climate goals, the "SOLCORL" project aims to halt the relentless rise in global temperatures by advancing low-carbon solutions and catalyzing new markets for carbon-neutral technologies. This project focuses on the catalytic conversion of CO2 into valuable fuels and chemicals through an innovative photocatalysis process that mimics natural photosynthesis using sunlight and semiconductors. "SOLCORL" proposes a multifaceted strategy encompassing the development of advanced photocatalytic materials and reactors essential for large-scale CO2 conversion. The project will exploit two-dimensional layered hydroxides (LDHs) coated onto bio-derived carbon substrates from brewery and distillery waste—an estimated 300 million tons are produced globally each year. These materials will be integrated into a solar concentrator system designed to enhance sunlight concentration, significantly boosting the photocatalytic conversion rates of CO2. The project's key deliverables include synthesising and characterising innovative photocatalysts, developing a scalable photocatalytic reactor, and disseminating results through peer-reviewed publications and international conferences. Additionally, the project offers extensive intersectoral and multidisciplinary training opportunities, equipping researchers with the skills to innovate and lead in the fields of materials science, renewable energy, and environmental sustainability. These training modules foster expertise in advanced photocatalytic processes and their application in industrial settings, enhancing the Researcher's career prospects. Through these efforts, "SOLCORL" aims to provide scalable, sustainable solutions to CO2 emissions, contributing to global net-zero goals.

Keywords: layered double hydroxide co2 capture and utilization biomass derived carbon waste to wealth reactor scale up solar energy utilization circular economy
DisruptivE Electrical Propulsion - Power Processing Unit (DEEP-PPU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Space
Destination: Open Strategic Autonomy in Developing, Deploying and Using Global Space-Based Infrastructures, Services, Applications and Data
Action type: Innovation actions
Countries involved: Spain,France,Slovenia,Latvia
Call: Technologies and generic building blocks for Electrical Propulsion (HORIZON-CL4-2022-SPACE-01, 2022)
Start date: 2022-10-01
End date: 2025-11-30
Duration (months): 38.0
Total project cost (EUR): 2464145.75
EU funding (EUR): 1798888.28
Participants: 6
Project status: SIGNED

The objective of DEEP-PPU project is to develop and introduce to the market a disruptive Power Processing Unit (PPU) for Electrical Propulsion Gridded Ion Thrusters. This solution will stand out with its outstanding 40% mass and 35% volume reduction compared to the existing solutions on the market, while reducing the cost of the unit by a factor of two. The DEEP PPU project will strengthen the EU's space sector competitiveness in the international market, while securing the autonomy of supply for critical technologies and equipment. The target PPU will be achieved through the use ground-breaking technologies in space, namely Gallium Nitride semiconductors and Commercial Off-The-Shelf components, together with the implementation of custom design of power magnetics, the integration of the Radio Frequency Generation module and the synergies with previous developments in the frame of GIESEPP (Gridded Ion Engine Standardised Electric Propulsion Platforms). A multidisciplinary team of entities across Europe has been set, providing the right background and expertise to perform the required activities. The proposed PPU product fits the HORIZON-CL4-2022-SPACE-01-12 topic (Technologies and generic building blocks for Electrical Propulsion), specifically addressing the second area of this topic “R&I on electrical power architecture and related components (Power Processing Unit, direct drive, etc.)”.

Keywords: electrical propulsion,power processing unit,git gridded ion thruster,rfg radio frequency generator,gan gallium nitride,cots commercial off the shelf
Acoustic Black Holes for Silent SYstemS (ABHSSYS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France,Spain,Czechia,Denmark,Belgium,Canada
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-03-01
End date: 2030-02-28
Duration (months): 48.0
Total project cost (EUR): 3604102.25
EU funding (EUR): 3345584.04
Participants: 14
Project status: SIGNED

The ABHSSYS project ambitions to disrupt noise reduction technologies while addressing the need for industrial decarbonization through a ground-breaking approach: Acoustic Black Holes (ABH). Unlike conventional noise reduction solutions, which often increase mass and carbon footprint, ABH offer significant noise reduction without adding weight. Across EU, 40% of the population is exposed to noise levels exceeding 55 dB(A), leading to health and social costs reaching 40 B€. Reducing noise pollution is therefore a central issue for the EU citizens well-being, and is associated with strong technological challenges in the field of vibroacoustics, particularly in the mechanical industry, one of the main source of noise pollution. ABH is a radically new technology and has strong scientific and industrial potentials, as it is intrinsically i) parsimonious and environmentally friendly: its use reduces the mass and volume of acoustic treatments by around 20%; ii) tunable: ABH enable considerable noise and vibration reduction with only minor or local modifications of the structuring, and are compatible with usual industrial processes; iii) multifunctional: ABH can be applied to many industrial fields without requiring new designs. Moreover, on top of all that, ABHSSYS is a green transition catalyst in terms of noise and vibration reduction. ABHSSYS's ambition is to train a new generation of 11 expert researchers in the field of vibro-acoustic engineering through an innovative interdisciplinary training programme. The consortium of ABHSSYS includes 7 academics, all specialists of ABH, building an exceptional team and 6 companies representing a wide range of fields of activity concerned with noise reduction under environmental constraint: Aeronautics (AIRBUS, BOMBARDIER), Aerospace industry (ORUP MORSBOL I/S), Pump industry (GRUNFOS), Acoustic services (SIEMENS), Innovative materials design (METACOUSTIC).

Keywords: acoustic black hole,acoustic performance,vibration damping,sound aborption
Personalized prognosis in smoldering myeloma through automated analysis of mutational signatures (MYELOMA-RISK)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy,Cyprus
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2023-07-01
End date: 2024-12-31
Duration (months): 18.0
Total project cost (EUR): 182142.86
EU funding (EUR): 150000.0
Participants: 2
Project status: CLOSED

Multiple myeloma (MM) is the second most common haematological cancer which is symptomless until the later stages, with few treatment options and poor long-term prognoses. Next-generation DNA sequencing (NGS) has been used to identify and characterise the process of clonal evolution and disease progression in asymptomatic MM, however, there remains no viable prognostic NGS method which can be used by clinicians to leverage different mutations to predict progression. The scientific literature indicates the methods under research utilise large genomic regions and significant coverage in sequencing that would result in prohibitively high costs of testing if applied to the clinical domain. The aim of this PoC project is to develop a complete, low-cost prognostic bioinformatics tool able to characterise the driver mutation signatures of MM in order to allow early diagnosis, monitor progression and potentially identify at risk patients that may benefit from early treatment to improve outcomes.
A Multi-fidelity Approach Enabling Automated High Precision in Cold Spray Repair (Core)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-01-01
End date: 2026-06-30
Duration (months): 18.0
Total project cost (EUR): 162857.14
EU funding (EUR): 150000.0
Participants: 2
Project status: SIGNED

The EU's manufacturing sector is facing a crucial challenge to achieve ambitious sustainability goals in the transition towards a circular economy. While repair and remanufacturing are key solutions to this issue, current techniques fall short due to limitations in handling complex (geometry and material-wise) parts, heat damage and a lack of automation. This results in a staggering amount of waste – over 167 million tons generated annually by the EU manufacturing industry alone. CoRe offers a solution based on Cold Spray (CS), a solid state (no melting) deposition technique, with significant potential to revolutionize the repair sector. Currently, the widespread establishment of CS in the repair realm is hindered by the limited geometrical accuracy and the lack of automation in deposit shape control. CoRe will pair the physics-based analytical concept developed within the originating ERC project, with computational models, ad-hoc experiments and artificial intelligence to develop a disruptively robust, unprecedentedly accurate and computationally efficient CS repair planning tool. This fully automated tool will be made interoperable with commercial robots to readily offer customized nozzle trajectory to minimize post-processing, material waste and lead time in repair. The accomplishment of CoRe objectives will set out a unique synergy between CS performance metrics (material flexibility, high deposition efficiency, unlimited build volume) and automation with geometrical accuracy, advancing the repair sector towards an extremely flexible, unprecedentedly scalable and remarkably customizable and sustainable level; this will open the door to the coveted "freedom and accessibility in repair" to a wide range of applications. CoRe will also explore target applications, production impact, and marketability of its output. This future-focused approach positions CoRe to lead a sustainable repair revolution.

Keywords: solid state deposition,toolpath planning,cold spay,repair