Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
New technologies in VAT reporting, collection and auditing: legal opportunities and challenges” (VATTECH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2023-12-24
Duration (months): 24.0
Total project cost (EUR): 219312.0
EU funding (EUR): 219312.0
Participants: 1
Project status: SIGNED

Billions of euros are being lost yearly by EU Member States (MS) due to fraud related to Value Added Tax (VAT) . VAT fraud erodes budgets of both MS and the EU and leads to distortions of competition. It affects honest businesses and consumers and violates the very fundaments of the Internal Market. The loss of tax revenue impedes the fulfilment of redistributive tasks of the MS and thus their role in protection of basic economic and social rights of individuals. The advancement of new technologies – including big data analysis and ever more complex algorithms – has the potential to significantly reducing VAT fraud across the EU. The overall aim of the project on “New technologies in VAT reporting, collection and auditing: legal opportunities and challenges” (VATTECH) is to investigate – from a legal perspective - the opportunities and challenges in the use of new technologies in reporting, collection and auditing of VAT. I will do this by: a) Mapping the new technologies used within the VAT area, identify the most efficient ones along with the legal base and background related to these technologies; b) Evaluating the identified technologies based on functionality and consistency with taxpayer’s rights, and the existing EU’s legal framework; c) Based on a) and b), assessing the potential (functional as well as legal) for extension and harmonization of the evaluated technologies to the whole of EU. My ambition is to provide important, new insights into the EU VAT system, and through that, to make a significant contribution to the improvement of the tools to combat VAT fraud, administrative cooperation and exchange of information on VAT between and across EU MS.

Keywords: value added tax,european vat,tax avoidance,tax fraud,new technologies,tax administration,human rights,fundamental freedoms
Automata in Number Theory (ANT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: France
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-10-01
End date: 2022-03-31
Duration (months): 78.0
Total project cost (EUR): 1438745.0
EU funding (EUR): 1438745.0
Participants: 1
Project status: CLOSED

Finite automata are fundamental objects in Computer Science, of great importance on one hand for theoretical aspects (formal language theory, decidability, complexity) and on the other for practical applications (parsing). In number theory, finite automata are mainly used as simple devices for generating sequences of symbols over a finite set (e.g., digital representations of real numbers), and for recognizing some sets of integers or more generally of finitely generated abelian groups or monoids. One of the main features of these automatic structures comes from the fact that they are highly ordered without necessarily being trivial (i.e., periodic). With their rich fractal nature, they lie somewhere between order and chaos, even if, in most respects, their rigidity prevails. Over the last few years, several ground-breaking results have lead to a great renewed interest in the study of automatic structures in arithmetics. A primary objective of the ANT project is to exploit this opportunity by developing new directions and interactions between automata and number theory. In this proposal, we outline three lines of research concerning fundamental number theoretical problems that have baffled mathematicians for decades. They include the study of integer base expansions of classical constants, of arithmetical linear differential equations and their link with enumerative combinatorics, and of arithmetics in positive characteristic. At first glance, these topics may seem unrelated, but, surprisingly enough, the theory of finite automata will serve as a natural guideline. We stress that this new point of view on classical questions is a key part of our methodology: we aim at creating a powerful synergy between the different approaches we propose to develop, placing automata theory and related methods at the heart of the subject. This project provides a unique opportunity to create the first international team focusing on these different problems as a whole.

Keywords: automata theory,transcendence,algebraic independence,mahler s method,subspace theorem,diophantine geometry,arithmetics in characteristic p,g functions,enumerative combinatorics,decidability
Global Glass Adornments Event Horizon in the Late Iron Age and Roman Period Frontiers (100 BC - AD 250) (GLOBALGLASS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-05
End date: 2017-10-04
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The project is multidisciplinary comparative research on the cross-cultural consumption of personal adornments, known as glass annulars, i.e. rigid, ring-shaped objects composed of coloured glass, used by the inhabitants of the European northwest borderland regions during the transition from the Late Iron Age to Roman period, c. 100 B.C. – A.D. 250. This project introduces the pan-European ‘glass adornments event horizon’, which signals the existence of an active multicultural community with its own forms of decorative identification in the borderland regions. It will assess the evidence for this phenomenon, firstly, in four north-western European countries: Germany, the Netherlands, Belgium, and United Kingdom, and, secondly, explore its regional ramifications, by concentrating on one area, United Kingdom, in order to understand the manifestation of this inter-cultural event in a local setting. The project combines thorough literary and museum research with scientific and hands-on experiments, and pays particular attention to engaging and disseminating the results to the wider public. It challenges long-standing perceptions related to the function and gender nature of glass adornments. It investigates the mobility of materials, artefacts and craftspeople, and reconstructs the networks of interethnic craft interaction in borderland zones. It analyses the transformative role these annulars played in the formation of inter-European and regional identities in a transitional period when new cultural forms and practices emerged in the European Northwest.

Keywords: archaeology,late iron age and roman northwestern europe,glass adornments,interethnic craft,production technology,identity,frontiers
New corrugated cardboard for active packaging to extend shelf-life of fresh fruits and vegetables (FRESHTRAY)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Spain
Call: Accelerating the uptake of nanotechnologies advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-02-01
End date: 2017-06-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

SAECO is a Spanish SME founded in 1979 in Murcia. We have more than 30 years of experience in corrugated cardboard manufacturing and nowadays we sell more than 100 million square meters of corrugated cardboard (equivalent to the size of Paris) and more than 70,000 tonnes of recycled paper and fibre per year. One of our strategic markets is the agricultural sector, particularly the fruits and vegetables (F&V) market, to which we supply more than 24 million square meters of corrugated cardboard, used to manufacture trays and boxes in different sizes and formats. Despite the high post-harvesting standards in the EU horticultural sector, almost half of the fruits and vegetables produced in the EU are thrown away before reaching the plate. We want to contribute to face this challenge by proposing an innovative solution to extend shelf-life of fresh fruits and vegetables, since the existing ones are either ineffective or too costly to be implemented. Through collaboration with experiences researchers, we have developed an active corrugated cardboard that, thanks to a coating based on nano-encapsulated natural antimicrobial compounds (formulation & application patented), protects fresh fruits and vegetables from microorganisms’ assault. This means that safety, quality and freshness of fruits and vegetables are enhanced, resulting in less food waste. By significantly extending shelf-life of the products (+70%), FreshTray can help F&V growers and retailers to reach longer markets and supply high quality and safe fresh products to the consumers. Less food losses result in higher revenues. Consumers will equally benefit from acquiring fresher, with less preservatives and safer fruits and vegetables. Market projections suggest that FreshTray will reach 2 million square meters the first year of commercialisation, and will rise until 15 million the fifth year. Net profit is estimated to be around 2.5 M€, with a ROI of 3.5 creating 13 FTE jobs.

Keywords: nanotechnology,shelf life,active packaging,cardboard,food waste,fruit and vegetables
A new paradigm for centromere biology: Evolution and mechanism of CenH3-independent chromosome segregation in holocentric insects (CENEVO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: France
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-04-01
End date: 2024-11-30
Duration (months): 80.0
Total project cost (EUR): 1497500.0
EU funding (EUR): 1497500.0
Participants: 2
Project status: SIGNED

Faithful chromosome segregation in all eukaryotes relies on centromeres, the chromosomal sites that recruit kinetochore proteins and mediate spindle attachment during cell division. Fundamental to centromere function is a histone H3 variant, CenH3, that initiates kinetochore assembly on centromeric DNA. CenH3 is conserved throughout most eukaryotes; its deletion is lethal in all organisms tested. These findings established the paradigm that CenH3 is an absolute requirement for centromere function. My recent findings undermined this paradigm of CenH3 essentiality. I showed that CenH3 was lost independently in four lineages of insects. These losses are concomitant with dramatic changes in their centromeric architecture, in which each lineage independently transitioned from monocentromeres (where microtubules attach to a single chromosomal region) to holocentromeres (where microtubules attach along the entire length of the chromosome). Here, I aim to characterize this unique CenH3-deficient chromosome segregation pathway. Using proteomic and genomic approaches in lepidopteran cell lines, I will determine the mechanism of CenH3-independent kinetochore assembly that led to the establishment of their holocentric architecture. Using comparative genomic approaches, I will determine whether this kinetochore assembly pathway has recurrently evolved over the course of 400 million years of evolution and its impact on the chromosome segregation machinery. My discovery of CenH3 loss in holocentric insects establishes a new class of centromeres. My research will reveal how CenH3 that is essential in most other eukaryotes, could have become dispensable in holocentric insects. Since the evolution of this CenH3-independent chromosome segregation pathway is associated with the independent rises of holocentric architectures, my research will also provide the first insights into the transition from a monocentromere to a holocentromere.

Keywords: centromere evolution,chromatin,cenh3,cenp a,cenp t,kinetochore
Mixotrophy in marine microalgae for renewable biomass production (MMM-REBIO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-11-04
End date: 2021-11-03
Duration (months): 24.0
Total project cost (EUR): 191852.16
EU funding (EUR): 191852.16
Participants: 1
Project status: CLOSED

Diatoms are unicellular eukaryotic algae (microalgae) and one of the most common and diverse type of marine phytoplankton. Thanks to a flexible cell metabolism, they dominate in environmental conditions normally unfavorable for photosynthesis, i.e. freezing seawater, low light intensity and short photoperiod. Moreover, diatoms are able to synthesize storage lipids (20-50% of cell dry weight) that can be used for production of renewable biomass and high-value fatty acids. However, the success of these microalgae as feedstock depends on lowering the production cost. The proposed project aims to develop mixotrophic cultivation (i.e. the simultaneous use of light and carbon dioxide for photosynthesis and organic carbon for respiration) to maximize growth and outdoor productivity for selected strains from the Swedish west coast. The focus will be on the bloom-forming coastal diatom Skeletonema marinoi (S. marinoi) whose sequence annotation is ongoing, and the recent knowledge on mixotrophic growth of the model diatom Phaeodactylum tricornutum will be employed. The main objectives will be: i) using the bloom-forming S. marinoi to better understand mixotrophic metabolism in diatoms; ii) exploring the optimal mixotrophic conditions for enhanced productivity of S. marinoi; iii) investigating the potential industrial applications of S. marinoi when cultivated under mixotrophy. To achieve these objectives, an interdisciplinary approach including computational, biophysical, analytical, biotechnological and biological methods will be employed. A mixotrophic outdoor cultivation of marine microalgae in the dynamic climate of the Swedish west coast could provide a higher total production of renewable biomass for industry.

Keywords: diatoms,mixotrophic growth,photosynthesis,respiration,fatty acids
Oscar: The first device for managing a warehouse of articles able to visually recognise any label without the need of a barcode. (Oscar)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

VH Technology srl invented and designed a device able to automatically identify products by recognising their label when the product passes in front of the device camera. It recognises the product by looking at the label as a human would do. Allowing automatic warehouse management without the need of a barcode, RFID or other types of specially designed labels. This device uses sophisticated machine vision technology developed by VH Technology and is the first worldwide. A patent application has been filled. PCT application: PCT/EP2016/062247. The idea was initially born to answer a specific need: Cellar management. Today it is mostly performed in a manual way since wine bottles do not necessarily have a barcode (or may have same barcode for different vintages) and applying RFID tag on each bottle is expensive and time consuming. Manual inventory is more prone to errors, therefore frequent cellar inventory is necessary which is tedious and time consuming. Moreover manual inventory is very ineffective in preventing frequent losses of valuable bottles. Since our solution is well suited for cellar management VH Technology decided that the first device using this technology to be developed and launched on the market would target cellar management. At the same time VH Technology intends to apply this technology in multiple other fields. VH Technology developed 4 prototypes which have been extensively tested and have demonstrated technical feasibility, ease of use as well as significant efficiency increase compared to cellar management. Initial target: Restaurants, hotels, wine bars, wine shops, private wine collectors. To be extended to other labelled products. Market: Worldwide. Objectives phase 1: Detailed marked analysis to improve Oscar. Examine other applications/markets for our device. Objectives phase 2: From Oscar prototype to final product development (design to manufacture).

Keywords: image recognition,simpler warehouse management,automatic recognition of any product label,restaurants,hotels,small shops,cellar management,innovation
Bringing to market the world’s first integrated medical cooling system for minimizing brain damage in stroke patients. (CUCUMBER)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Germany,Germany,Finland,Sweden
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2020)
Start date: 2020-12-01
End date: 2025-05-31
Duration (months): 54.0
Total project cost (EUR): 3759322.5
EU funding (EUR): 2936494.0
Participants: 4
Project status: SIGNED

Stroke-related disabilities remains a major challenge faced by patients, their families and healthcare systems worldwide and is estimated to cost healthcare systems over €45B/year. In Europe, there are over 1.1M new incidences of stroke per year, a third of which will result in permanent disabilities such as limited mobility and affected cognitive function. These handicaps are a result of the brain damage caused by blocked blood flow to the brain, as well as further damage following the recanalization of an arterial blockage. Targeted temperature management (TTM), also known as 'brain cooling', is a method that has proven effective in reducing brain injury in sudden cardiac arrest patients. Extrapolation of TTM to stroke will have a tremendous impact on patient outcomes, however, the limited functionalities of current cooling technologies prevent this realization. The CUCUMBER consortium, whose expertise range from engineering, manufacturing, clinical neurology and stroke, are working to change this paradigm by developing CoolConnect, the world's first cooling device that accommodates the needs of stroke treatment to improve patient’s outcome, survival, and neurological outcome. CoolConnect is an integrated device composed of 3 components (RhinoChill, BrainCool, and BrainTemp sensor), which come together to address the 3 critical phases of brain cooling, 1)Early cooling, 2)Cooling during reperfusion and 3)maintenance cooling. CoolConnect is the only solution in development designed for this purpose. FTI grant is requested to fast-track the market launch of CoolConnect by 2024, to ensure broad and sustainable uptake in the following years. Our main aim is to validate CoolConnect in a large, multicenter trial, and to implement all market access and communication activities critical for broad market adoption. There are >288,000 eligible patients for CoolCoonect per year in EU/US, and yearly revenues of €56M can be anticipated following 5 years of commercialization.

Keywords: therapeutic hypothermia,medical cooling,targeted temperature management,stroke,ischemic,thrombectomy,brain damage,brain injury,reperfusion,reperfusion injury
Relative Role of Reproductive Isolating Barriers During Speciation (IsoBar)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-03-11
End date: 2019-07-12
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Understanding the appearance of reproductive isolation is essential for understanding mechanisms underlying the origin of species. This project aims at understanding the relative importance of different isolating barriers during adaptive speciation by looking at patterns of genomic divergence. I will use numerical modelling, analysis of RNAseq data from several biotypes (incipient species) of a model organism (pea aphid), and will perform mating experiments to address four research questions: (1) Which patterns of genomic divergence arise when different isolation barriers apply? (2) Which patterns of genomic divergence do pea aphids show? (3) Do pea aphids biotypes have behavioural mate choice? (4) Which reproductive barriers are needed for the completion of speciation in hybridizing biotypes? Successful implementation of this project will improve my career perspectives, because it's training objectives were chosen to guarantee addressing skills gaps, diversifying experience and strengthening existing skills. European Research and Society will also benefit from results of this project, both though academic and economic pathways.