Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Train-to-NZEB: The Building Knowledge Hubs (Train-to-NZEB)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Market uptake of energy innovation
Action type: Coordination and support actions
Countries involved: Ireland,Ukraine,Germany,Ireland,Romania,Türkiye,Romania,Bulgaria,Bulgaria,Czechia
Call: Construction skills (H2020-EE-2014-3-MarketUptake, 2014)
Start date: 2015-06-01
End date: 2018-11-30
Duration (months): 42.0
Total project cost (EUR): 1426333.75
EU funding (EUR): 1426333.75
Participants: 13
Project status: CLOSED

The Train-to-NZEB project is designed to establish a functioning network of training and consultation centres (Building Knowledge Hubs, BKHs), providing practical trainings, demonstrations and complex consulting services for the implementation of nearly-zero energy buildings (NZEB). Using the improved training facilities, the BKHs will provide enhanced capacity for conduction of trainings on curricula developed on BUILD UP Skills II, thus reaching a significant number of workers not covered by the initiative. Additionally, BKHs will offer trainings for highly-qualified building professionals and demonstrations for non-specialists with decision-making authority, which, combined with administrative and financial consultancy service, will result in increased capacity for implementation of NZEB projects in the involved countries. In order to reach this goal, the following objectives are set: 1. Development of publicly available Terms of Reference for the setting up of the BKHs; 2. Adaptation of existing and development of new training programs; 3. Actual setting up of 4 training and consultation centres (BKHs) according to the Terms of Reference; 4. Building of internal capacity through train-the-trainer activities, targeting at least 90 qualified trainers; 5. Actual training courses according to annual training plans, resulting in: (a) 120 training courses for construction workers, targeting additional qualification of 2400 trainees; (b) 24 training courses for highly-qualified building specialists, targeting additional qualification of 480 trainees; (c) 36 training courses for non-specialists, targeting additional qualification of 720 trainees; 6. Strict monitoring and evaluation for constant improvement of the offered services. 7. Setting up of a web-based networking platform providing facilities for knowledge sharing and exchange between the BKHs; 8. Conduction of a targeted dissemination and communication campaign to increase the market demand for NZEB projects.

Keywords: nzeb,building knowledge hubs bkhs,construction workers,highly qualified building specialists,non specialists with decision making authority,demonstrations,consulting services,networking
Understanding the diversity of galaxy morphology in the era of large spectroscopic surveys (GMGalaxies)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-10-01
End date: 2025-09-30
Duration (months): 72.0
Total project cost (EUR): 1741230.0
EU funding (EUR): 1741230.0
Participants: 1
Project status: SIGNED

Galaxies are the building blocks of structure in the Universe; this proposal seeks to understand how their shapes, colours and dynamics are determined. For example, what happened in the history of some galaxies to transform them into passive ellipticals while others, seemingly of the same mass and in the same environment, are star-forming spirals? Even such a basic question about the link between morphology and star formation has not yet been answered, revealing our theories of galaxy formation are inadequate. This is a major concern in an era where understanding the shapes of galaxies and how they relate to the underlying dark matter is essential for progress in precision cosmology. This project will build the missing link between the history of a galaxy and its observational properties (i.e. between cause and effect) by using numerical simulations. Current research in this area rightly gives significant attention to the crucial problem of how feedback – energy input from supernovae, active galactic nuclei, and more – affect observable properties. But as well as investigating this avenue, GM Galaxies will uniquely make use of my new technique (“genetic modification”) to systematically investigate the role of the galaxy’s merging and accretion history at high resolution. To distinguish the fingerprints of history from the effects of feedback, we will compare to rich new data from integral field unit surveys; these reveal, for example, galactic metallicity and velocity maps. My pilot study for this project shows that such measures of a galaxy disambiguate between alternative formation routes to galaxies which would appear similar by photometric measures alone. Similarly, we will make predictions for the observable properties of the gas reservoir surrounding galaxies and for integral field observations at high redshift. In this way we will make a predictive account of how galactic structure is determined by the interaction of the accretion history with feedback.

Keywords: galaxy,morphology,feedback,accretion,spectroscopy,kinematics,metallicities
Barbara is an Operating System Software Platform which enables IoT device manufacturers to boost their level of security, reduce time-to-market, and reduce costs. (Barbara-IoT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-06-01
End date: 2018-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Internet of Things (IoT) has the potential to greatly influence the European economy. It was forecasted that IoT would bring revenue of approximately 2,133 billion U.S. dollars in Western Europe by 2020. Strong pressure by keen investors and managers wanting to unlock the value of Industrial Internet of Things (IIoT) is leading to exponential growth, but the growth is happening too fast given inherent complexity of implementations. In this sense, with IoT there are appearing solutions for very critical sectors, where security is a must. Health solutions, Banking, etc.. cannot fail, and IoT solutions should be ready for this level of service. With the available tools, IT managers have no option but to take a patch-work approach that is costly, time consuming, causing fragmentation and interoperability issues, while exposing major security vulnerabilities that are left at the mercy of cyber attackers. In fact, many companies lack the skills required to handle the complexity and are burdened by heavy costs of security consultants or software needed to ‘fix’ the vulnerabilities after installation, if and when detected. In the emerging fast-growing market, Barbara project is an IoT Open Source Operating System and Management Platform focused on enhancing security for connected IoT devices. The market for IIoT devices itself is huge, worth 457 US Billions in 2020. TipTap Labs has developed Barbara, a solution that directly addresses the user pains and challenges of IIoT deployment, delivering a new operating system and management platform specially designed for connected devices, with a core focus on security designed into the system. The team has years of experience in security and IIoT implementations, understanding real user needs and industry trends. Barbara has the potential to completely disrupt the market, generating enormous value for industries and the company itself.

Keywords: operating system,industry 4 0,industrial iot,cloud platform,connected devices,machine to machine,cybersecurity
Validation of a novel class of cyclophilin inhibitors for the treatment of non-alcoholic steatohepatitis (CYPNASH)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: United Kingdom
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2019-10-01
End date: 2021-12-31
Duration (months): 27.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Non-alcoholic steatohepatitis (NASH) is an increasingly prevalent chronic liver disease (3-4% of the US population) for which there is currently no approved drug therapy. In the absence of innovative treatments healthcare costs associated with this disease are set to triple over the next decade. To address this unmet medical need, the pharmaceutical industry is currently pursuing a range of liver fibrosis drug discovery programs based on different mode of actions. A compelling mechanism for treating liver damage is pharmacological modulation of the mitochondrial permeability transition pore in liver cells via inhibition of the protein cyclophilin D. However existing cyclophilin inhibitors based on peptidic macrocyclic scaffolds are challenging to optimize into sub-type selective orally bioavailable agents suitable for clinical trials of liver fibrosis. As part of basic research activities undertaken during ERC StG EBDD to validate a computational-biophysical drug discovery platform, we have discovered a structurally novel family of small molecules that inhibit cyclophilins by targeting a previously unexplored binding pocket. The objective of this POC is to identify a lead compound in this family with potential for development towards a NASH clinical candidate. Such a candidate will form the basis of follow-on lead optimisation programs pursued via partnering or out-licensing with a pharmaceutical partner. The activities of this POC will focus on assembling a data package of in vitro DMPK, in vivo PK, in vitro sub-type selectivity and in vitro and in vivo efficacy measurements in relevant cellular and animal models of liver fibrosis. This POC has been designed in consultation with a major pharmaceutical company and assembles a team of physical and biological scientists and business development executives to maximize the likelihood of delivering a valuable preclinical NASH asset.

Keywords: drug discovery,medicinal chemistry,liver fibrosis,cyclophilin
Resilient forest value chains – enhancing resilience through natural and socio-economic responses (RESONATE)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Research and Innovation actions
Countries involved: Austria,Austria,Germany,Germany,Spain,Ireland,Austria,Spain,Spain,Belgium,Finland,Croatia,Finland,France,Czechia,Netherlands,Denmark,United Kingdom
Call: Sustainable wood value chains (H2020-RUR-2020-2, 2020)
Start date: 2021-04-01
End date: 2025-03-31
Duration (months): 48.0
Total project cost (EUR): 4994062.5
EU funding (EUR): 4994062.5
Participants: 20
Project status: SIGNED

Climate change poses a major challenge for European forests, demonstrated by recent extreme events and forest disturbances of unprecedented intensity. As climate change continues, adverse impacts on the stability and production capacity of European forests could undermine the role of forests and the forest-based sector as a central pillar of the European Green Deal. To mitigate increasing disturbance risks, more effort is needed in prevention, particularly by improving the resilience of European forests and associated value chains. Forest owners need better guidance in adapting the management of their forests to coping with climate-induced forest disturbances and changes in functioning. Similarly, the forest-based sector will require substantial innovation capacity to respond to changes in profitability, unpredictable wood flows, and a gradual change in tree species. There is an urgent need to improve the scientific understanding on how resilience of Europe’s forests and forest value chains can be improved. RESONATE aims to guide decision-making towards enhancing resilience of forests and forest value chains in response to four resilience challenges: i) changing suitability of tree species due to climate change; ii) increased risks of forest disturbances; iii) changing societal demand on forest products and ecosystem services; iv) biodiversity decline. With an integrated resilience and vulnerability assessment, RESONATE investigates how past and current site factors and management affect forest system resilience in different forest types and management systems across Europe. Based on scenario analysis, foresight studies with active stakeholder engagement, and policy analysis, future-oriented response strategies to enhance forest and forest value chain resilience will be elaborated. RESONATE further highlights and balances trade-offs in decision making and delivers user-oriented recommendations and decision support with tools including, e.g., a Resilience Dashboard.

Keywords: climate change adaptation,forest value chain,drought,disturbances,changes in social demand,safeguarding biodiversity
Pathway to a Competitive European FC mCHP market (PACE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Innovation actions
Partnership: FCH2 (Art-187)
Countries involved: Germany,Germany,Germany,Germany,Germany,Germany,Germany,Germany,Germany,Germany,Germany,Italy,Switzerland,Belgium,Switzerland,Belgium,France,Netherlands,Denmark,United Kingdom
Call: Large scale demonstration of µCHP fuel cells (H2020-JTI-FCH-2015-1, 2015)
Start date: 2016-06-01
End date: 2023-04-30
Duration (months): 83.0
Total project cost (EUR): 91681934.33
EU funding (EUR): 33932752.75
Participants: 28
Project status: SIGNED

PACE is a major initiative aimed at ensuring the European mCHP sector makes the next move to mass market commercialisation. The project will deploy a total of 2,650 new fuel cell microCHP units with real customers and monitor them for an extended period. This will: - Enable fuel cell mCHP manufacturers to scale up production, using new series techniques, and increased automation. By 2018, four leading European manufacturers (Bosch, SOLIDpower, Vaillant and Viessmann) will have installed capacity for production of over 1,000 units/year (each will install over 500 units in PACE). These production lines will test the manufacturing techniques which will allow for mass market scale up and the reductions in unit cost which will come from associated economies of scale. - Allow the deployment of new innovations in fuel cell microCHP products, which reduce unit cost by over 30%, increase stack lifetime to over 10 years (by end of the project) and improve the electrical efficiency of all units. - Create a large dataset of the performance of the units, which will demonstrate the readiness of fuel cell mCHP as a mass market product. This will prove that fuel cell mCHP can be a leading contributor to reducing primary energy consumption and GHG emissions across Europe. - Allow the units in the trial to be pooled in a large scale test of the concept of aggregating and controlling the output from mCHP to act as a virtual power plant. This will be achieved in a project run by EWE on a section of the German grid earmarked for smart grid trials. - Act as the basis for an effort to standardise mCHP products in Europe, helping create a more efficient market for both installers and component suppliers. The project will provide an evidence base which will be used in a dissemination campaign targeting policy makers (who can provide supportive policies for the next wave of mCHP roll-out) and increasing awareness of the technology within the domestic heating sector (main route to market).

Keywords: commercialisation,demonstration,fuel cell micro chp,fuel cell mchp,large scale,deployment,combined heat and power,supply chain,support networks
Fast tracking market adoption of a novel immune-based diagnostic for improving antibiotic stewardship: automation, piloting and health economics (AutoPilot-Dx)

Framework: Horizon 2020 — Societal Challenges
Action type: Innovation actions
Countries involved: Germany,Italy,Italy,Germany,Israel,Sweden
Call: Fast Track to Innovation Pilot (H2020-FTIPilot-2015-1, 2015)
Start date: 2016-09-01
End date: 2019-08-31
Duration (months): 36.0
Total project cost (EUR): 2923250.0
EU funding (EUR): 2293900.0
Participants: 6
Project status: CLOSED

MeMed has completed development of ImmunoXpert™, an in vitro diagnostic test that leverages the body’s immune system to accurately differentiate between bacterial and viral infections. A breakthrough in infectious disease diagnosis, ImmunoXpert™ overcomes limitations of traditional diagnostics, outperforming standard of care. ImmunoXpert™ recently received regulatory European clearance (CE-IVD) and represents a close-to-market innovation. Market entry points include emergency department and hospitalized pediatric patients with respiratory tract infections (RTI) and fever without source (FWS), for which ImmunoXpert™ is uniquely positioned to improve patient management and health economics. In children, RTIs account for 50% of doctor visits and hospitalization. Fever accounts for 10-25% of pediatric ED visits, with as many as 20% without identifiable source. The global market for ImmunoXpert™ diagnosis of pediatric RTI/FWS is €2.8B (EU is €560M). To fast track market adoption across Europe we propose: •To transition ImmunoXpert™ from a hands-on laboratory assay to Tecan’s hands-free, rapid automated laboratory platform to increase clinical utility and economic benefit •To roll-out ImmunoXpert™ to EU pilot hospitals with the goal of managing 1200 pediatric patients to evaluate performance and clinical utility in real working conditions •To perform health economics analysis and establish reimbursement strategy AutoPilot-Dx is a cross sector effort (industry, KOLs, outcome researchers) highly aligned with H2020-FTIPilot’s goals and Societal Challenges: it will reduce ImmunoXpert™’s time to market and provide a road-map for sustainable market uptake; a H2020 first-time applicant is involved; the project will enable MeMed and Tecan to scale-up in line with their business strategies; the immune-based diagnostics will improve antibiotic stewardship, providing better, personalized, care for children with RTI/FWS and help fight antibiotic resistance – a global health threat

Keywords: diagnostics,infectious disease,antibiotic stewardship,biomarkers,antibiotic resistance,host response,health economics,clinical utility
ONO - THE URBAN UTILITY VEHICLE FOR TODAY AND TOMORROW’S DRIVING (ONO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-01-01
End date: 2019-04-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In Europe alone, there are over 500.000 delivery trucks roaming our streets and producing 6 million tons of CO2 each year. They are also a primary cause for traffic jams in most major cities. These vehicles are extremely harmful, not only to the environment, but also to the quality of life in cities. Air and noise pollution, road congestion and lack of space are problems seriously affecting big cities. Tretbox GmbH is introducing a new category of electric vehicle – called ONO - which is not only better for cities, but also offers reduced operational costs for logistics operators and is designed for demand growth in today’s and tomorrow's cities: we replace the gasoline trucks with a combination of city depots and a new type of electric cargo bicycle. We allow operators flexibility in the capacity of the vehicle according to changing workloads. For the drivers, we offer the ergonomics, the comfort and safety they would hope for. ONO offers logistics market customers the option to switch from their existing combustion engine trucks to modern electric cargo bicycles. By doing so, they save money, time and gain flexibility while enhancing their brand perception. The logistics market is growing exponentially, yet still employing antiquated delivery methods not adapted to their needs. Tretbox GmbH, a German company founded in 2016 and based in Berlin, is solving the aforementioned problems thanks to a talented team of designers and engineers, led by our co-founder, former Head of Design for the Volkswagen Group.

Keywords: last mile delivery,electric vehicle,co2 emissions,zero emissions,vehicle as a service,safety
Pilot line production of functionalized CNTs as thermal interface material for heat dissipation in electronics applications (SMARTHERM)

Framework: Horizon 2020 — Societal Challenges
Action type: Innovation actions
Countries involved: Germany,Sweden,France,France
Call: Fast Track to Innovation Pilot (H2020-FTIPilot-2015-1, 2015)
Start date: 2016-01-01
End date: 2019-09-30
Duration (months): 45.0
Total project cost (EUR): 3968145.0
EU funding (EUR): 2942701.0
Participants: 5
Project status: CLOSED

The global economy is benefiting from the fast evolution of the semiconductor industry. The primary driving force of the semiconductor industry is the increasing integration density, which has lead not only to higher transistor density but also to increasing power density. Power density is expected to increase up to 135 W/cm2 in 2024 for single chip packages. This puts significant stress on thermal management technology. Obviously, there is a need for improved thermal management within the field, and innovative TIMs constitutes a key component in reaching this goal. TIMs with dispersion of CNTs in polymer matrices for improved thermal conductivity have been reported. However, the thermal conductivity in these composites is insufficient and fundamental limitations stem from the huge interfacial contact resistance between the CNTs and the contact resistance between the CNT ends and target surfaces. Therefore, SMARTHERM project is initiated aiming to build up a pilot production line for high-performance TIMs based on functionalized CNTs. The utilization of vertically aligned CNT structure eliminated the CNT-CNT contacts along the heat transfer path and the functionalization at the CNT ends dramatically decreased the contact resistance. The main outcomes of the SMARTHERM project are two types of CNT based TIMs manufactured in a roll-to-roll manner which allows large scale production at industrial level. The TIMs will be demonstrated by two demonstrators proposed by TRT. The consortium consists of 5 partners from 3 European countries and integrates competence from 2 big companies, 2 SMEs and 1 university. TRT and SHT have been funded by the FP7 framework programme NANOPACK and SMARTPOWER, in which SHT and TRT have obtained great amount of knowledge on CNT based TIMs. Therefore, SMARTHERM project will make use of the previous research results and push the material a big leap forward to the market.

Keywords: roll to roll,carbon nanotube,thermal interface material,thermal management,electronics,large scale production