Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Networking Ecologically Smart Territories (NesT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Ecuador,Ireland,Poland,Poland,France,France,France,France,United States
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2020, 2020)
Start date: 2021-09-01
End date: 2025-02-28
Duration (months): 42.0
Total project cost (EUR): 989000.0
EU funding (EUR): 989000.0
Participants: 12
Project status: SIGNED

The principal aim of Networking Ecologically Smart Territories (NEST) will be to test the hypothesis that digital diversification, which will be explored as noodiversification and technodiversification as the conditions of resilience of human societies, holds the key to a reinvention of contemporary, proletarianising, industrial economics. For this purpose, a large transdisciplinary research mobility project is necessary in order to articulate local territorial situations with international concerns in the context of the Anthropocene. The aims will be achieved through an international and intersectorial exchange of researchers and staff across the academic and non-academic partners of NEST. The NEST consortium is made of 11 partners, 5 EU academic partners TU Dublin (IRL), IRI (FR), Paris Lumières (FR), USLK (PL) and UGE (FR), 2 Third Country academic Partners Uartes (EC), Berkeley (US) and 4 non-academic partners, DCC (IRL), CSSD( FR), Factory of the Living (PL), and Disnovation (FR) . There are 3 academic WPs.By extending the critique of digital technology already undertaken by the Digital Studies Network to reconsider the foundations of computer theory in relation to the concepts of locality, negentropy, anti-entropy, data economy and networked AI by developing the concepts of technodiversity and cosmothenchics (WP1). To experiment and introduce new forms of collective responsibility through Territorial experimentation, enabling new forms of citizen participation in local governance through contributory research (WP2). To experiment and develop a network of territorial laboratories of digital contributory research in order to study the constraints acting on life and the archipelagos of ecological niches by species inhabiting the same territoires, with a view to generating local understandings of living singularities and functional cooperations between territorial-laboratories and academics in view of the planetary threat. (WP3)
Disruptive green membrane for sustainable chemical and energy industries (GREENMEM)

Framework: Horizon 2020 — Societal Challenges
Action type: SME instrument
Countries involved: Switzerland
Call: H2020-EIC Accelerator pilot –SME Instrument - Green Deal (H2020-EIC-SMEInst-2018-2020-4, 2020)
Start date: 2020-12-01
End date: 2022-11-30
Duration (months): 24.0
Total project cost (EUR): 3422312.5
EU funding (EUR): 2395618.75
Participants: 1
Project status: CLOSED

UniSieve is a Switzerland-based cleantech company originating from ETH Zurich. We provide advanced molecular separation solutions for a wide range of applications of different scales, ranging from propylene or hydrogen purification to biogas upgrading. Our priority is to supply customers with a unique separation solution that is well compatible with its existing infrastructure, while effectively contribute to sustainable economic and environmental benefits. Our platform technology enables a unique combination of various “molecular sieving” particles into polymeric membranes, yielding reliable separation solutions. This innovative membrane technology has been developed since 2013 at the Institute of Chemical and Bioengineering of ETH Zurich. We provide an opportunity for customers to increase product recovery by up to 90% of currently lost resources. As our membrane production process is scalable and compatible with standard roll coating devices, we are able to fabricate membranes at a price point that has never achieved in the industry before. This competitive advantage allows UniSieve to produce at scale. UniSieve is now ready to deliver demonstrators in our customers’ facilities and prepare ramp up for scaled-up production. UniSieve aims to achieve a 16% share of the chemical and energy industries for its technology in the next 10 years. The GreenMem project will yield a total >€86.3M in additional revenue by 2026. The project is expected to create >290 jobs by the same time. We are fully aligned with Green Deal objectives, contributing to savings of more than 8.15 million tons in CO2 emissions and 5 million tons + of propylene resources recycled per year until 2050.

Keywords: mof materials,chemical,biogas,nanotechnology,membranes,gas separation,propylene upgrading,hydrogen upgrading,product recovery,energy savings,separation technologies
Short linear interaction motifs as specificity determinants in the ubiquitin system – discovery, mechanisms and therapeutic opportunities (UBIMOTIF)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Estonia,Italy,Israel,Germany,Switzerland,Sweden,United Kingdom,United Kingdom,United Kingdom,Denmark
Call: Innovative Training Networks (H2020-MSCA-ITN-2019, 2019)
Start date: 2019-12-01
End date: 2024-05-31
Duration (months): 54.0
Total project cost (EUR): 4143173.11
EU funding (EUR): 4143173.11
Participants: 11
Project status: SIGNED

A major challenge is the lack of therapeutic approaches for numerous human diseases, which poses a societal challenge. The ubiquitin system is a major promising source for novel therapeutic approaches but its potential has not been fully exploited due to limited insight and lack of researchers trained in understanding and identifying avenues to target the ubiquitin system. Ubiquitin ligases and deubiquitinating enzymes (DUBs) comprises enzymes that actively add or remove ubiquitin from proteins to regulate cell physiology. How these enzymes selectively recognize their substrates is largely unknown but an emerging theme is that a globular domain in the enzyme binds a short linear interaction motif (SLiM) in the substrate. SLiMs are short peptide motifs that constitute ideal entry points for understanding the ubiquitin system as they provide detailed insight into substrate selection and how this regulates the underlying biology. Further, SLiMs provide direct routes to therapeutic exploitation as they serve as peptide scaffolds for drug development and tools to highjack the ubiquitin system. The potential of SLiMs has not been capitalized upon because a method for efficient identification was missing, interactions between relevant partners were lacking and this has hampered training of young researchers. UBIMOTIF overcomes these barriers by exploiting novel technological advances to identify SLiMs and uniting outstanding complementary researchers and industrial partners with a common vision to provide outstanding training of early career scientist in SLiMs and the ubiquitin system. The UBIMOTIF topic provides ideal training of young researchers, as it requires a multidisciplinary and intersectorial approach providing training in multiple cutting-edge technologies. The impact of UBIMOTIF will be unprecedented insight into the ubiquitin system, novel therapeutic opportunities and a skilled workforce that can fill the exhausted pipelines of European companies.

Keywords: ubiquitin,ubiquitin ligases,dubs,peptides,proteins,slims,protacs
Establishing services to “Enhancing the innovation management capacity of SMEs that are members of the EEN Tunisia. (APII-H2020-GA4-20-21)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Tunisia
Call: H2020 ENTREPRISE EUROPE NETWORK GA4 2020-2021 (H2020-EEN-GA4, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 85000.0
EU funding (EUR): 85000.0
Participants: 1
Project status: SIGNED

The general objective of this action is establishing services, which help SMEs to optimize this innovation value chain by enhancing their capacity of innovation management. It is make the EEN Tunisia network the main support instrument for innovation in Tunisian SMEs. The services described below are intended to contribute to a balanced development of the business and technology of the companies consulted leading to their growth and the improvement of their competitiveness, which be impactful positively on the economy.

Keywords: innovation,eimc,apii
A SECURE HEALTHCARE ENVIRONMENT FOR INFORMATICS RESILIENCE (HEIR)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Improve cyber security
Action type: Research and Innovation actions
Countries involved: Israel,Germany,Germany,Cyprus,Norway,Switzerland,Greece,Romania,Greece,Norway,France,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Digital security, privacy, data protection and accountability in critical sectors (H2020-SU-DS-2019, 2019)
Start date: 2020-09-01
End date: 2023-08-31
Duration (months): 36.0
Total project cost (EUR): 4999975.0
EU funding (EUR): 4999975.0
Participants: 19
Project status: SIGNED

The health sector is steadily becoming the de facto target for cyberattacks. Based on the most recent ENISA report at the end of 2018, cybersecurity incidents have shown that the healthcare sector is one of the most vulnerable. Focusing specifically on Electronic Medical Devices (EMD), they suffer from numerous and multi-layered vulnerabilities . Default, weak or no password authentication for remote connections, unencrypted traffic or obsolete and insecure cryptographic algorithms, unsupported operating systems, outdated, unmanaged and vulnerable software are among the most serious problems that jeopardise both their smooth operation and the data aggregated and stored. The vision of HEIR is to provide a thorough threat identification and cybersecurity knowledge base system addressing both local (in the hospital / medical centre) and global (including different stakeholders) levels, that comprises the following pillars: (i) Real time threat hunting services, facilitated by advanced machine learning technologies, supporting the identification of the most common threats in electronic medical systems based on widely accepted methodologies such as the OWASP Top 10 Security Risks and the ENISA Top 15 Threats; (ii) Sensitive data trustworthiness sharing facilitated by the HEIR privacy aware framework; (iii) Innovative Benchmarking based on the calculation of the Risk Assessment of Medical Applications (RAMA) score, that will measure the security status of every medical device and provide thorough vulnerability assessment of hospitals and medical centres; (iv) The delivery of an Observatory for the Security of Electronic Medical Devices; an intelligent knowledge base accessible by different stakeholders, providing advanced visualisations for each threat identified in RAMA and facilitating global awareness on EMD-related threats. Last, HEIR will set up a broad European network for establishing good security practice in all regulatory frameworks to reduce market access.

Keywords: real time threat hunting,global benchmarking,secure data management
Advanced integrated obstacle and track intrusion detection system for smart automation of rail transport (SMART2)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: European rail initiative
Action type: Innovation actions
Partnership: Shift2Rail (Art-187)
Countries involved: Germany,Serbia,Romania,Slovenia,United Kingdom
Call: Advanced obstacle detection and track intrusion system for autonomous freight train (H2020-S2RJU-OC-2019, 2019)
Start date: 2019-12-01
End date: 2022-11-30
Duration (months): 36.0
Total project cost (EUR): 1708737.5
EU funding (EUR): 1499528.75
Participants: 7
Project status: CLOSED

SMART2 project will build on the results achieved in project SMART by advancement, innovation and implementation of SMART2 on-board long-range all-weather obstacle detection (OD) and track intrusion detection (TID) system. 2 new systems will be also researched, innovate and developed: advanced SMART2 trackside (TS) /airborne OD&TID systems. All 3 systems will be integrated into a holistic OD&TDI system via interfaces to central Decision Support System (DSS). A holistic approach to autonomous obstacle detection for railways would enable increased detection area including areas behind a curve, slope, tunnels and other elements blocking the train’s view on the rail tracks, in addition to a long-range straight rail-tracks OD. SMART2 platform will be flexible and open for interfacing additional OD&TDI modules based on future technologies. SMART2 project aims at developing a working prototype of the foreseen holistic OD&TDI that will be evaluated in different real-world railway use-case scenarios (TRL 6/7). The SMART2 will review and assess the relevant requirements, including existing ones (in regulation or related to current technologies), as well as those relating to emerging technologies (as being defined in past and ongoing R&D projects). Based on this analysis, a new set of lower complexity requirements will be proposed for a harmonised approach concerning all systems involved in the implementation of ATO GoA 3/4, in general, and, particularly for the OD&TID System.

Keywords: autonomous obstacle detection,track intrusion detection,autonomous freight train
Chronic inflammation and cardiovascular risk (INF-CVD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-16
End date: 2021-11-04
Duration (months): 24.0
Total project cost (EUR): 178320.0
EU funding (EUR): 178320.0
Participants: 1
Project status: CLOSED

Cardiovascular disease is the leading cause of death and illness globally. Preventive therapies can avoid or delay the occurrence of cardiovascular events, provided that one can identify individuals at risk and intervene before problems manifest. Recent scientific developments have established that inflammation has a prominent role in the development of cardiovascular diseases; but routine screening of inflammatory markers to assess cardiovascular risk in the general population is currently unfeasible. It is known however that certain diseases cause high and chronic inflammation, and patients affected by these conditions may be at increased risk of cardiovascular events. Yet, studies so far have been limited by the relatively modest absolute numbers of patients affected, so that for many of these conditions evidence is insufficient to guide clinical decisions. The aim of this research proposal is to investigate the associations between a range of chronic inflammatory conditions and different types of cardiovascular disorders, by using one of the largest longitudinal healthcare datasets available for research purposes in the world. The study design leverages the potential of ‘big data’ to explore complex disease associations through a unique combination of skills – my own knowledge of epidemiology and experience with the studied data set; my host supervisor’s expertise in statistical models best suited for the analysis of longitudinal data; and interdisciplinary clinical expertise through an international network of collaborations. A better understanding of cardiovascular risks associated with chronic inflammatory conditions may help guidelines and clinicians to focus on patients for which screening and treatments are more likely to have an effect, and improve the prevention of cardiovascular diseases. Differences between conditions may further point towards biological functions underlying these complications and inform the design of future research.

Keywords: cardiology,inflammation,epidemiology
Climatic and temporal control on microbial diversity-ecosystem functioning: insights from a novel conceptual model (CLIMIFUN). (CLIMIFUN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,United States
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-08-01
End date: 2019-07-31
Duration (months): 36.0
Total project cost (EUR): 239191.2
EU funding (EUR): 239191.2
Participants: 2
Project status: CLOSED

Despite the importance of soil microbial communities for ecosystem functioning and human welfare, little is known about the mechanisms controlling the composition and diversity of these communities, and the role of their attributes in providing multiple ecosystem functions and services such as nutrient cycling and decomposition (i.e. multifunctionality). Many studies have identified climate, stage of ecosystem development and soil characteristics as main drivers of plant and animal diversity. However, much less is known about the interactive effects of climate, soil properties and time in controlling microbial diversity and multifunctionality during ecosystem succession. This lack of knowledge hampers our ability to predict microbial community shifts and their consequences for ecosystem functioning under climate change, and limits the inclusion of soil microbes in global biogeochemical models. The main research objective of this action is to gain a deeper insight into the patterns and mechanisms that drive soil microbial diversity and multifunctionality under changing environments. We will use a novel conceptual framework combining long-term chronosequences, climate change experiments and structural equation modelling to quantitatively evaluate the role of time, climate and multiple soil drivers in controlling microbial diversity and multifunctionality. The research outlined in this proposal includes a range of state-of-the-art biochemical, molecular and genomic methods for the analysis of microbial communities and multifunctionality that ensure the maximum utility and impact of our results. Altogether, CLIMIFUN will reveal the factors that control soil microbial diversity and multiple functions linked to plant production and nutrient cycling under a changing environment. This work will thus address a key knowledge gap relevant to supporting increases in global demand for food and fibre over the next decades, and a research priority for H2020.

Keywords: pedogenesis,microbial diversity,ecosystem functioning,climate change,nutrient cycling long term chronosequences
Getting Ready for EST (GREST)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Spain,Italy,Spain,Sweden,Switzerland,United Kingdom,United Kingdom
Call: Design studies (H2020-INFRADEV-1-2014-1, 2014)
Start date: 2015-06-01
End date: 2018-05-31
Duration (months): 36.0
Total project cost (EUR): 3956730.0
EU funding (EUR): 2977273.0
Participants: 13
Project status: CLOSED

The present project is intended to take the European Solar Telescope (EST) to the next level of development by undertaking crucial activities to improve the performance of current state-of-the-art instrumentation. Legal, industrial and socio-economic issues will also be addressed, as key questions for the attainment of EST. The particular developments and strategic tasks proposed here can be summarised in the following specific objectives: (i) Boosting new generation detectors, with the development of two prototype sensors, one for large-format imaging and a the other for high-precision polarimetry, the evaluation of an existing large format wavefront sensing camera is also addressed; (ii) Development of a capacitance-stabilised Fabry-Perot prototype for a high quality control of the parallelism of the etalon plates; (iii) new techniques for 2D solar spectro-polarimetry; with integral field units based on multi-slit image slicers or a microlens-fed spectrograph; (iv) development of large format liquid-crystal modulators, required for the large-format sensors that will be needed for the new generation large aperture telescopes ; (v) evaluation of the performance of the EST-MCAO deformable mirrors to improve the design and performance of this system; and (vi) strategic work to covering industrial, financial and legal issues related the future construction and operation of EST. The following issues will be addressed: • Elaboration of a census of the European solar physics community • Analysis of the technological expertise of European companies in the different countries and their potential expertise related with the construction needs of EST • Revision and update of the construction budget of EST • Stimulation of a discussion of all these aspects within the consortium EAST With all these elements in hand, the project will be in the condition to present a definite proposal for detailed design, construction, managing and operation of EST.

Keywords: solar telescopes advanced detectors narrow band tunable etalons 2d spectro polarimetry liquid crystal variable retarders multi conjugate adaptive optics strategic works