Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Understanding fire, weather and land cover interactions from long-term terrestrial observations and satellite data in a north to south transect in Europe and North Africa (GRADIENT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Switzerland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-07-01
End date: 2017-09-30
Duration (months): 15.0
Total project cost (EUR): 117137.25
EU funding (EUR): 117137.25
Participants: 1
Project status: CLOSED

Long-term historical fire records extending back to the late 1800s are very rare worldwide. Three such long-term historical fire data have been found for this research proposal; (i) Switzerland, central Europe (1900-2014), (ii) Greece, south Europe (1897-2014), and (iii) Algeria, north Africa (1870-2014) which together with the spatial-explicit reconstruction of recent fire history from Landsat satellite images (1984-2016), give a unique and excellent opportunity to understand fire, weather and land use/land cover (LULC) interactions in a north to south transect. Differences in bio-geographical characteristics provided by the three study areas, located on a large geographical gradient covering two continents give the opportunity to document the role of fires in different biomes, to explore cross-scale issues and assess how fire-weather-LULC relationships vary across different scales, especially under a climate change context. This research proposal consists of three topics that correspond mainly to three different scales. The specific objectives are: (i) the identification of trends, patterns and relationships between forest fires, weather, LULC and socio-economic parameters from long-term observations, (ii) the reconstruction of recent fire history and the assessment of burning patterns and fire selectivity on an annual basis from satellite images, and (iii) the exploration of post-fire vegetation dynamics and recovery patterns for selected large fire events using time series satellite images. Those objectives will contribute to the better understanding of fire, weather and land cover interactions, and will therefore provide knowledge for fire and land cover management practices, especially under a climate change context. Understanding of post-fire vegetation dynamics and recovery will help the mitigation of short and long-term consequences of fire occurrence. The knowledge acquired from the past will help to understand current processes and project them to future.

Keywords: wildland fires,burning patterns,weather,fire selectivity,land cover changes,fire history reconstruction,climate change,time series landsat and modis images,post fire vegetation dynamics
The EUropean TRAnsplantation and INnovation (EU-TRAIN) consortium for improving diagnosis and risk stratification in kidney transplant patients (EU-TRAIN)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Understanding health, wellbeing and disease
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Germany,Switzerland,France,France,France,France,Netherlands,United Kingdom
Call: New concepts in patient stratification (H2020-SC1-2017-Two-Stage-RTD, 2017)
Start date: 2018-01-01
End date: 2024-06-30
Duration (months): 78.0
Total project cost (EUR): 6641546.0
EU funding (EUR): 6641546.0
Participants: 16
Project status: SIGNED

Rejection is the major cause of allograft failure with dramatic consequences in terms of mortality, morbidity and increased cost for the society. The field of transplantation lacks a robust assessment of risk stratification. Thus, it impairs the development of relevant clinical trials to address graft and patient outcomes. We formed the EU-TRAIN project by gathering reference kidney transplant centres in a fully operating European network including 12 partners. Our ambitious but realistic goals are: to provide clinicians with innovative and accessible tools for early prediction of individual risk of allograft rejection and transplant loss; to personalise clinical management and treatment and; to improve allograft outcomes. This project will engineer a risk stratification system applied to kidney transplant patients by analysing the integration of several layers of data (clinical, histological, immunological data as well as gene expression and novel biomarkers) - the TRAnsplant Comprehensive Evaluator of Risk (EU-TRACER). EU-TRACER will be generated and validated in 2 dedicated studies including a randomised control trial. Translation to patients will be achieved by delivering: 1) A multiplex non-invasive biomarker system for the stratification and immune monitoring of low and high risk kidney recipients; 2) A prognostic system for individual risk stratification for allograft rejection and failure that will assist decision making via an interactive web interface. The EU-TRACER, developed with our 3 industrial partners, will define a new standard of care in transplantation. The EU-TRACER will have the potential for a large implementation and diffusion in other centres in Europe and will be suitable for industrial collaboration.

Keywords: kidney allograft rejection,risk prediction,precision diagnosis,biomarkers,gene expression,integrative epidemiology,smart data,multidimensional analysis
Capacity with a pOsitive enviRonmEntal and societAL footprInt: portS in the future era (COREALIS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Italy,Italy,Spain,Spain,Cyprus,Belgium,Belgium,Switzerland,Finland,Greece,Finland,Greece,Poland,Netherlands,Netherlands
Call: The Port of the future (H2020-MG-2017-Two-Stages, 2017)
Start date: 2018-05-01
End date: 2021-04-30
Duration (months): 36.0
Total project cost (EUR): 5150540.0
EU funding (EUR): 5150540.0
Participants: 22
Project status: CLOSED

Ports are essential for the European economy; 74% of goods exported or imported to the EU are transported via its seaports. At the same time, the challenges they face are only getting greater: Volumes of cargo increase while they also arrive in a shrinking number of vessels: Post-Panamax vessels have a capacity of more than 18k containers. Port operators need to comply with increasingly stricter environmental regulations and societal views for sustainability. A sustainable land-use strategy in and around the port and a strategic transition to new, service-based, management models that improve capacity and efficiency are paramount. They are key enablers for ports that want to keep pace with the ocean carriers needs and establish themselves as trans-shipment hubs with a ‘societal license to operate’; for ports whose land strategy, hinterland accessibility and operations are underpinned by circular economy principles. COREALIS proposes a strategic, innovative framework, supported by disruptive technologies, including IoT, data analytics, next generation traffic management and 5G,for modern ports to handle future capacity, traffic, efficiency and environmental challenges. It respects their limitations regarding the port land, intermodal infrastructure and terminal operation. It proposes beyond state of the art innovations to increase efficiency and optimize land-use, while being financially viable, respecting circular economy and being of service to the city. Through COREALIS, the port will minimize its environmental footprint to the city, it will decrease disturbance to local population through a reduction in the congestion around the port. It will be a pillar of business innovation, promoting local startups in disruptive technologies of mutual interest. COREALIS innovations are key both for the major deep sea European ports in view of the new mega-vessel era, but also relevant for medium sized ports with limited investment funds for infrastructure and automation.

Keywords: ports of the future,capacity,operational efficiency,circular economy,mega vessels,societal innovation,predictive analytics,traffic management,strategic roadmap,serious games
Development and mechanistic investigations of efficient Fe-catalysed asymmetric C–H activation (AsymFeCH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2022-09-30
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: CLOSED

The importance of chirality in bioactive molecules is well established with only one enantiomer exhibiting the desired biological activity. To date, more than 90% of chiral drugs on the market are supplied as racemates potentially causing side-effects or of uncertain bioactivity. The enantioselective synthesis of chemicals has risen to address such issues with enantioselective catalytic C–H activation standing out due to its atom economy, step efficiency, and avoidance of substrate pre-functionalization. So far, metal-catalysed enantioselective inner sphere C–H activation relies mainly on precious and/or toxic metals, such as Pd and Ru, limiting the reaction’s applicability. Therefore, efforts are currently being made to replace such metals with more benign 3rd row transition metals. Nevertheless, only one report of such transformation has been reported with Fe despite Fe being extremely desirable due to its low cost, toxicity and high natural abundance. The AsymFeCH project will address this issue through the development of non-toxic, sustainable and inexpensive Fe-catalysed enantioselective C–H activation reactions. For this purpose, low valent Fe complexes with chiral phosphines will be used as precatalysts in the catalytic hydroarylation of allenes or alkenes with aromatic ketones. The mechanism and origin of enantioselectivity of the developed reactions will then be delineated through a unique combination of spectroscopies and kinetic studies. Subsequently, the acquired mechanistic understanding will be used for further reaction development with more challenging substrates (imines and 1,1-diphenylketone derivatives) setting the foundations for the scientific and industrial communities to advance the field of asymmetric Fe-catalysed C-H activation. This will not only lead to the sustainable and greener synthesis of pure chiral products affecting the pharmaceutical and materials sectors but will also make Europe less dependent on Pd, an imported precious metal.

Keywords: catalysis,iron,c h activation,asymmetric,mechanism
Heavy Duty Gas Engines integrated into Vehicles (HDGAS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Innovation actions
Partnership: EGVI (cPPP)
Countries involved: Austria,Germany,Italy,Austria,Germany,Germany,Germany,Germany,Spain,Spain,Italy,Finland,Finland,Sweden,France,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Future alternative fuel powertrains and components for heavy duty vehicles (H2020-GV-2014, 2014)
Start date: 2015-05-01
End date: 2018-04-30
Duration (months): 36.0
Total project cost (EUR): 27791129.36
EU funding (EUR): 19890587.5
Participants: 25
Project status: CLOSED

The overall objective of HDGAS is to provide breakthroughs in LNG vehicle fuel systems, natural gas and dual fuel engine technologies as well as aftertreatment systems. The developed components and technologies will be integrated in up to three demonstration vehicles that are representative for long haul heavy duty vehicles in the 40 ton ranges. The demonstration vehicles will: a) comply with the Euro VI emission regulations b) meet at minimum 10% CO2 reduction compared to state of the art technology c) show a range before fueling of at least 800 km on natural gas; d) be competitive in terms of performance, engine life, cost of ownership, safety and comfort to 2013 best in class vehicles. Three HDGAS engine concepts/technology routes will be developed: - A low pressure direct injection spark ignited engine with a highly efficient EGR system, variable valve timing comprising a corona ignition system. With this engine a stoichiometric as well as a lean burn combustion approach will be developed. Target is to achieve ≥ 10% higher fuel-efficiency compared with state of the art technology - A low pressure port injected dual fuel engine, a combination of diffusive and Partially Premixed Compression Ignition (PPCI) combustion, variable lambda close loop control and active catalyst management. Target is to achieve > 10% GHG emissions reduction compared with state of the art technology at a Euro VI emission level, with peak substitution rates that are > 80%; - A high pressure gas direct injection diesel pilot ignition gas engine, that is based on a novel injector technology with a substitution rate > 90% of the diesel fuel. Target is to achieve same equivalent fuel consumption (< 215g/kWh) and 20% lower GHG emissions than the corresponding diesel engine. HDGAS will develop all key technologies up to TRL6 and TRL7 and HDGAS will also prepare a plan for a credible path to deliver the innovations to the market.

Keywords: lng vehicle fuel system,natural gas,dual fuel,engine,heavy duty,euro vi,emissions targets,direct injection,gas injection,exhaust aftertreatment system,demonstration vehicle
Impact of Neuromedin U in type 2 immunity and mucosal defence (INIMUD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-07-01
End date: 2019-11-08
Duration (months): 24.0
Total project cost (EUR): 148635.6
EU funding (EUR): 148635.6
Participants: 1
Project status: CLOSED

Group 2 innate lymphoid cells (ILC2) are critical players in mucosal defense, tissue homeostasis and inflammation. ILC2 development and function have been widely perceived to be programmed. Nevertheless, how ILC2 perceive, integrate and respond to environmental cues remains mostly unexplored. Here we hypothesize that ILC2 sense their environment and exert their function as part of a novel neuronal-ILC2 unit orchestrated by neuromedin U (NmU) signaling. We propose to employ genetic, cellular and molecular approaches to decipher how NmU and its receptor Neuromedin Receptor 1 (Nmu-R1) set ILC2 function and preserve tissue homeostasis at mucosal barriers. To this end, ILC2-specific loss and gain of function mutant mice for Nmu-R1 will be used. Strikingly, preliminary data demonstrate that NmU is a major regulator driving ILC2 cytokine production. Under this Marie-Curie fellowship, we aim to establish a novel molecular interplay between neuron derived peptides and ILC2 function in mucosal homeostasis. Finally, this proposal will reveal new pathways with potential therapeutic value in mucosal disorders that are major public health concerns.

Keywords: neuromedin u,neurons,type 2 innate lymphoid cells,mucosal immunity
One Way , Your Link! (WayLink)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-06-01
End date: 2018-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Abitat SIT has 20 years of experience on Geographic Information System (GIS) and geo-coding services (geo-coding converts addresses into geographic coordinates to be placed on a map): with a turnover of more than 2 million Euro is one of the leader in the Italian market and has created the product Way!Link. GPS devices help them get their way easily and Location Based Sercives (LBS) give them useful information by knowing where they are; nevertheless, tell to these systems to go is not so easy: they need either GPS coordinates or an address, that requires several details. Therefore, this situation is not user friendly and it is time consuming. Furthermore, 1/3 of on-line address is wrong, making sometimes difficult for the users reaching the targeted location. In the past internet had the same problems too: websites had IP coordinates which they turn to be domain name (e.g. 74.125.53.100 = google.com). Way!Link is a similar solution for physical location: a short, unique, address tag links with the users wherever they are, like a domain name for the WWW. Our tag is called GeoLink: the users put it into the system the way they want (they create the GeoLink) and the system associates the coordinates to the venue they want to reach. Our initial business strategy is based on our strong relationship with clients and suppliers: Abitat Sit is closely collaborating with several international company, especially with Autodesk France and AECOM International Development. In addition, we are distributor of one of the biggest Romanian IT company, Syneto, which guaranteed us support for the project. Therefore, our project is highly scalable at worldwide level, also considering the growing importance of the GIS systems and the market trends: through Way!Link we aimed to become partner of major multinational companies (e.g. Google, TomTom, etc.), and we are targeting the 0,01% (1,8 M Euro) of the market by 2023 and the 0,1% by 2030 (18 M Euro).

Keywords: geolocation
Interfacing Levitated Optomechanics with Superconducting Qubits (ELOTEQ)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2020-04-30
Duration (months): 12.0
Total project cost (EUR): 112466.88
EU funding (EUR): 112466.88
Participants: 1
Project status: CLOSED

The aim of this project is to establish how the quantum state of an aspherical nanoparticle can be coherently interfaced with a superconducting circuit. Its main efforts can be summarized by two goals: (i) We will develop the theoretical tools required to manipulate the ro-translational quantum state of a levitated nanoparticle possessing a monopole and higher multipole moments by connecting it to a superconducting qubit. (ii) We will investigate how entanglement between the nanoparticle and the circuit can be exploited for earth-based macroscopic interference experiments and for coherence-enhanced force and torque sensing. Networking levitated nanoscale objects with quantized electrical circuits and qubits combines the high Q-factors and isolation of the former with the scalability and control of the latter. This project will point the way towards new fundamental tests of quantum physics and towards quantum technology.

Keywords: levitated optomechanics,matter wave interferometry,foundations of quantum physics
A neuro-computational account of success and failure in acquiring communication skills (NeuroCompSkill)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Israel
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-08-01
End date: 2025-07-31
Duration (months): 72.0
Total project cost (EUR): 2499888.0
EU funding (EUR): 2499888.0
Participants: 1
Project status: SIGNED

Why do most people acquire expertise with practice whereas others fail to master the same tasks? NeuroCompSkill offers a neuro-computational framework that explains failure in acquiring verbal and non-verbal communication skills. It focuses on individual ability of using task-relevant regularities, postulating that efficient use of such regularities is crucial for acquiring expertise. Specifically, it proposes that using stable temporal regularities, acquired across long time windows (> 3 sec to days) is crucial for the formation of linguistic (phonological, morphological and orthographic) skills. In contrast, fast updating of recent events (within ~ .3- 3 sec), is crucial for the formation of predictions in interactive, social communication. Based on this, I propose that individuals with difficulties in retaining regularities will have difficulties in verbal communication, whereas individuals with difficulties in fast updating will have difficulties in social non-verbal communications. Five inter-related work packages (WP) will test the predictions that: (WP1) behaviourally – individuals with language and reading difficulties will have impoverished categorical representations, whereas individuals with non-verbal difficulties will be slow in adapting to changed statistics. (WP2) developmentally – poor detection of relevant regularities will be an early marker of related difficulties. (WP3) computationally – profiles of impaired inference will match the predicted time window. (WP4) neuronally – dynamics of neural adaptation will match the dynamics of behavioural inference. (WP5) structurally – different brain structures will be associated with the different time windows of inference. NeuroCompSkill is ground-breaking in proposing a unifying, theory based, testable principle, which explains core difficulties in two prevalent developmental communication disorders. Its 5 WPs will lay the foundations of a comprehensive approach to failure in skill acquisition.

Keywords: perceptual learning,statistical learning,reverse hierarchy theory,experts,sensori motor skills,bayesian,inference,prediction error,reading disability,language,social skills