Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
New Handles for String Scattering Amplitudes (StringScat)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 1449500.0
EU funding (EUR): 1449500.0
Participants: 1
Project status: SIGNED

String Theory is currently the only known theoretical framework that unifies the concepts of quantum mechanics and gravity in a consistent way. As such, it makes concrete quantitative predictions for the interaction of gravitons in the form of scattering amplitudes. Unfortunately, the technical complexity of the theory is staggering, and most attempts to directly compute such scattering amplitudes beyond the leading orders have been stifled by technical difficulties. This project aims to overcome these difficulties by applying three new and unconventional tools to the problem. StringScats's three-pronged strategy leverages numerical techniques, saddle-point approximation, and exact evaluation techniques such as the Hardy-Littlewood circle method. It seeks to crack the necessary hard computations in string perturbation theory and obtain a long-sought glimpse into the quantum properties of gravity. Among the numerous potential rewards we would, for example, for the first time ever get a direct handle on the analytic structure of a quantum gravity amplitude and understand the very high energy behaviour of String Theory and how it interacts with the UV-finiteness of the theory. StringScat will also have ramifications in neighboring fields such as black hole physics, S-matrix bootstrap, number theory and the geometry of the moduli space of Riemann surfaces that features prominently in the calculation. Scattering amplitudes represent one of the handful of accessible windows into quantum gravity and hence offer great potential for tangible progress in the subject. Despite the enormous importance of this topic in physics, it has received far too little attention. Recent advances in the understanding of formal aspects of the string perturbation theory, developments of numerical methods, and the increasing synthesis of the subject with mathematics, now permit us to attack the problem in earnest.

Keywords: scattering amplitudes,string theory,quantum gravity
Flexible energy systems Leveraging the Optimal integration of EVs deployment Wave (FLOW)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Clean and competitive solutions for all transport modes
Action type: Research and Innovation actions
Partnership: 2ZERO (co-programmed)
Countries involved: Spain,Denmark,Netherlands,Italy,Germany,Ireland,Czechia,Belgium
Call: System approach to achieve optimised Smart EV Charging and V2G flexibility in mass-deployment conditions (2ZERO) (HORIZON-CL5-2021-D5-01, 2021)
Start date: 2022-07-01
End date: 2026-06-30
Duration (months): 48.0
Total project cost (EUR): 9873630.0
EU funding (EUR): 9873628.0
Participants: 32
Project status: SIGNED

FLOW boosts and demonstrates multifaceted EV smart charging and V2X integration into energy systems thanks to a range of comprehensive solutions providing answers to the needs of all actors involved. These solutions include highly replicable user-centric products, concepts, configurations and mechanisms to optimise operation. Cross-sector harmonisation and standardisation is delivered to facilitate activities of stakeholders and EV users. Advanced interoperable solutions enhance planning, operation and assessment of EV charging for seamless integration into the energy system and identification of the most appropriate scenario based on a multi-criteria model, leveraging appropriate business models and tailored services. FLOW also delivers multi-actor orchestration to ensure data exchange and synchronisation across actors for VGI and EV flexibility services. These solutions are deployed in 5 demonstrations (including 2 testbeds and 3 large-scale demos) in CZ, IE, IT, DK, and ES covering a wide range of applications (e.g., V1G/V2B/V2H/V2G, public/private/semi-public, urban/rural/touristic, car/small- & medium commercial) to validate and quantify the benefits associated with enabling and valorising EV flexibility, alleviating grid challenges, and fostering mobility and energy decarbonization. Expected impacts include GHG emission reduction of 0.6MtCO2/y, grid reinforcement saving up to 1.3B€/country, increase local RES by 14% and avoid RES curtailment by 4TWh. The consortium includes 26 partners from 9 European countries covering the entire value chain, including OEM, technology providers, CPOs, aggregators, DSOs, TSO, ICT developers, RTOs experts in users, mobility, harmonisation, optimisation tools, energy integration and leveraging the networks of umbrella associations from the electromobility and the DSOs. These ensure replicability and scalability to foster the EV penetration trends, thanks also to comprehensive communication, dissemination and exploitation actions

Keywords: vehicle to grid,v2x,electrical vehicles,evs,ev chargers,smart charging,user participation,multi actor orchestration,flexibility,grid decarbonization,res,der,ai digital tools,optimization
Remote NMR (R-NMR): Moving NMR infrastructures to remote access capabilities (R-NMR)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Coordination and support actions
Countries involved: Germany,Italy,Spain,France,Croatia,Latvia,Netherlands,Norway,Poland,Portugal,Sweden,Slovenia,Austria,United Kingdom,Hungary,Greece,Czechia,Denmark
Call: Transition to digital/remote research infrastructure service provision: lessons learnt, needs and best practices (HORIZON-INFRA-2021-DEV-01, 2021)
Start date: 2022-07-01
End date: 2025-06-30
Duration (months): 36.0
Total project cost (EUR): 1350000.0
EU funding (EUR): 1350000.0
Participants: 27
Project status: CLOSED

Nuclear magnetic resonance spectroscopy (NMR) is one of the major analytical methods applied in all chemical, physical, biological, and medical sciences. NMR's leading role stems from its analytical power in terms of molecular resolution, quantification, reproducibility, and broad application envelope. It requires sophisticated and expensive equipment, operated by scientists with diverse background ranging from service-oriented researchers to highly trained experts. The aggregated capital investment in European NMR facilities, operating at local, national, and European level, exceeds 500 Million Euro. The NMR community maintains excellent networking between sites and serves a broad community within the focal points of European research interests. With the application Remote-NMR (R-NMR), we wish to establish remote access for all NMR users throughout Europe. While routine NMR applications are routine in every university and in industry, more specialized applications are performed in dedicated research infrastructures offering access and help to local and outside users. During the pandemic, NMR infrastructures slowed down their operations to variable degrees, and particularly access by remote users dropped significantly, raising the need to establish standardized procedures for remote access to improve their resilience to adverse external factors. In this proposal an inclusive network of NMR-infrastructures throughout Europe will be established, surveying if and how remote access can be made possible according to the needs of the community, and implementing GDPR at facilities and sample shipment procedures. Routines for remote NMR-usage will be established, including dissemination of research and teaching protocols, archiving of data, and sample shipment. The overall CO2 footprint of the operation of the consortium will be evaluated, as well as its reduction due to the reduction of travels.

Keywords: nmr,remote acces,sample shipment,co2 monitoring,data archiving,remote teaching
Phase Separation and Oscillations in DNA Damage Response (PHOSCIL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed Matter Physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Denmark
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 1497672.0
EU funding (EUR): 1497672.0
Participants: 1
Project status: SIGNED

DNA damage response is a crucial function in living organisms, essential for maintaining genomic integrity. Two key processes prevent damage from propagating through generations: 1) DNA repair and 2) regulation of the cell cycle. Recent discoveries reveal that following DNA double-strand breaks, cells form biomolecular condensates at the site of damage through liquid-liquid phase separation. Another hallmark of the response is the initiation of oscillatory p53 concentration leading to cell cycle arrest. Despite being one of the most basic responses in cells, the physical mechanisms underlying this remains poorly understood as does the interplay between repair and regulation. I aim to derive the basic principles for condensates interacting with dynamical and oscillatory concentration fields. Here I will uncover how cells use fundamental mechanisms of physics to control formation and maintenance of condensates and how the emergence of oscillations can facilitate this task. The main highlights of PHOSCIL are the following: Revealing the physical mechanisms and inferring observables of condensate formation, by creating new methods for analysis, guided by theoretical models applied to novel experiments. Discovery of out-of-equillibrium phenomena of oscillatory and dynamic fields and their interactions with phase separation, generating conceptual advances in our understanding of biophysical systems. Uncovering the functional roles of phase sparation and oscillation on both repair and cell cycle regulation, advancing our fundamental understanding of, and ability to influence, cell fate decisions. To succesfully take these ambitious steps, I will combine theory and experiments that, taken together, will uncover novel concepts in the physics of phase separating systems and define a new chapter in our understanding of the DNA damage response.

Keywords: phase separations,dynamical systems,oscillations,cell regulation
Mediterranean Coral Performance under Warming and Iron enrichment conditions (MedCorP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark,Monaco,Switzerland
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-01-01
End date: 2025-01-31
Duration (months): 25.0
Total project cost (EUR): 230774.4
EU funding (EUR): 230774.4
Participants: 3
Project status: CLOSED

Mediterranean corals live in habitats with naturally high fluctuations of temperature and salinity, which could enable their survival under future extreme climatic scenarios. The nutritional status of corals is linked to the uptake of several micronutrients, which support cellular metabolism and growth. Among these, iron is a fundamental micronutrient for respiratory and photosynthetic processes. Although the iron concentration in seawater can be extremely low, Mediterranean coastal waters are subject to large quantities of nutrients, including iron, via runoff discharge from land. Most corals require a certain amount of iron to support their metabolic processes, but the assimilation rate, critical thresholds, and the allocation of iron in different spatial compartments of corals remain to be studied. This project aims to describe the effects of elevated temperature and iron enrichment on the microenvironment and ecophysiology of corals from the Mediterranean Sea through a novel combination of high-resolution microsensing technologies, bioimaging, and nanoscale spectrometry to explore coral metabolism at the microscale level. By measuring their metabolic responses during elevated temperature and iron availability, I will quantify the role of inorganic iron for coral cellular metabolism, develop a new coral health index for coral metabolic performance, and share this knowledge openly to target specific actions for stakeholders (e.g., government departments, environmental agencies, scientists). With this valuable fellowship, I aim to expand my scientific experience to assess coral health comprehensively at the microscale, which I strongly believe will be a novel way to observe and predict changes in the natural environment. The outcome will serve as a new tool to precisely understand the extent of environmental changes, in particular, the effects of ocean warming and iron concentration, predicting the consequences on the Mediterranean Sea in the short and long term.

Keywords: coral physiology ecophysiology metabolism performance health index micronutrients iron labeling microsensing multi stress experiment ocean warming nanoscale spectrometry
breakthrough technologies for an implantable artificial kidney (KIDNEW)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands,Belgium,France,Estonia,Poland
Call: EIC Pathfinder Open 2022 (HORIZON-EIC-2022-PATHFINDEROPEN-01, 2022)
Start date: 2023-05-01
End date: 2027-04-30
Duration (months): 48.0
Total project cost (EUR): 3375728.25
EU funding (EUR): 3293227.5
Participants: 7
Project status: SIGNED

Chronic kidney disease is a worldwide and ever-growing health crisis in which end-stage patients largely depend on intramural dialysis, placing a heavy burden on their life and on European health care systems. KIDNEW develops groundbreaking and modular technology to enable an implantable artificial kidney with better functional kidney replacement therapy (KRT) than currently available, without need for immunosuppressive drugs and at reduced costs. It provides proof of concept on three breakthrough technologies: 1. Solid-state miniature ultra-high flux silicon (Si)-based filter with a high-density of uniform nanopores through novel block copolymer self-assembly, and with novel hemocompatible biomimetic polymer polymer brush coating connected to a photonic clotting monitoring sensor and (thrombolytic) cleansing tool; 2. Solid-state bioreactor-grown kidney tubule cell monolayers on novel biomimetic Si-wafer based membrane with bioimpedance-based monolayer integrity monitoring and monolayer repair functionality using growth-factors; 3. Solid-state integrated functional biohybrid filter and tubule exchange units stacked in parallel in a multichip to demonstrate functional implantable KRT in goats. An implantable bioartificial kidney will provide more effective, more physiological, and economical sustainable KRT than dialysis. Eco-friendliness of proposed technologies, in line with the EU Green Deal, has recently been highlighted by the European Kidney Health Alliance. On the short to mid-term, the filter and/or tubule unit may enter niche-markets for extracorporeal use, in complementing rather than replacing current dialysis solutions. KIDNEW brings together scientists from the fields of clinical and regenerative nephrology (UMC Utrecht, NL), regenerative pharmacology (University Utrecht, NL), chip technology (Imec NL and Imec BE), optical sensing (Optofluid Technologies OÜ, EE), blood compatible coatings (CNRS, FR), and membrane technology (Me-Sep, PL).

Keywords: dialysis,kidney replacement therapy,krt,implantable,silicium,glomerulus,tubule,sensor,cleansing,repair
Quantum Materials: Harnessing Helicates and Radicals in Synergy (QuMaHHARIS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,Canada,United States
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-03-01
End date: 2028-02-29
Duration (months): 36.0
Total project cost (EUR): 252724.32
EU funding (EUR): 252724.32
Participants: 3
Project status: SIGNED

This is a multidisciplinary project that combines original organic and inorganic chemical synthesis with advanced electronic resonance spectroscopy to produce the next generation of multifunctional molecular quantum processor prototypes. Quantum technologies will embody the second quantum revolution, bound to change dramatically the landscape of information processing, communications and nanotechnology, thereby bringing profound changes to society. This could be realized through the coherent manipulation of the electronic or nuclear spin degrees of freedom. In this context, the growing importance of spin-bearing molecules as the potential physical platform to realize quantum technologies demands the design and precise characterization of the required molecular components with the appropriate functions. The objective of this proposal is to generate molecular qubits bearing functional components for their implementation. These components will be, a) single ion magnets (SIMs) to engender a local magnetic field for individual qubit operation, b) spin crossover (SCO) centers to provide a mechanism for tuning the qubit quantum coherence using light, c) molecular units exhibiting magnetocaloric effect (MCE) to generate a local mechanism for qubit refrigeration, or d) ancillary qubits to realize multiqubit quantum gates within molecules. A first period at Windsor University (Canada) will be dedicated to the synthesis of hybrid main group radical/coordination chemistry compounds. A six-month secondment at the National High Magnetic Laboratory in Florida (USA) will allow deep characterization of the compounds prepared and quality training in pulsed EPR. The final part at the University of Barcelona (Spain) will consist in incorporating the radical systems produced at Windsor as components of supramolecular assemblies. The last part will allow also advanced characterization with the local pulsed EPR infrastructurQuantum Materials: Harnessing Helicates and Radicals in Synergy

Keywords: epr spectroscopy
Intracellular Carrier Against Resistant microOrganisms (ICARO) (ICARO)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain,Belgium,France
Call: EIC Pathfinder Open 2021 (HORIZON-EIC-2021-PATHFINDEROPEN-01, 2021)
Start date: 2022-04-01
End date: 2026-03-31
Duration (months): 48.0
Total project cost (EUR): 2997047.0
EU funding (EUR): 2997047.0
Participants: 4
Project status: SIGNED

Intracellular pathogens and viruses elicit immune responses by presenting their antigens to T cells. At the same time, they have evolved immune evasion mechanisms which essentially reduce the antigenic repertoire that is presented to the immune system. To overcome this problem, the EIC-funded ICARO project proposes to use silicon-based microchips that carry pathogen antigens and can be internalised by immune cells to aid antigen presentation. These biochips are retained within cells for a long time and will provide the foundation for a novel vaccination strategy that can boost specific and long-lasting T cell responses. The consortium aims to develop standardized methods for ICARO manufacturing and functionalisation to be easily applicable to different pathogens, thus accelerating the generation of new vaccines in the future

Keywords: mems,vaccines,cd8,intracellular pathogens,
Novel long-term electricity storage technologies for flexible hydropower (STORE2HYDRO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Sweden,Norway,United Kingdom,Denmark,Italy,Austria
Call: Development of novel long-term electricity storage technologies (HORIZON-CL5-2023-D3-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 4315796.25
EU funding (EUR): 4315796.25
Participants: 11
Project status: SIGNED

The overarching aim of STORE2HYDRO is to introduce a new mindset for storage of electricity in connection with existing hydropower. Relatively small adjustments to existing hydropower facilities by retrofitting reversible pump turbine technology would allow the European electricity storage capacity to increase by 22TWh/y or more. The aim will be achieved by: i) Validated innovative mechanical solutions to TRL4-5 for larger-scale pumped, longer-duration storage of electricity in existing high head Reservoir-to-Reservoir (RtR) and low head Run-of-River (RoR) hydropower facilities. ii) Mapping untapped hydropower sources for long term electricity storage in Europe increasing the availability, robustness and safety of energy storage solutions. The novel technologies will enable the operators to run hydropower stations in a more efficient, cost effective and flexible manner than today also adapting to the energy system. This is without changing the regulating heights or volume of the reservoir/river reaches following the European Green Deal priorities. Also, turbine manufacturers can introduce new components for cost-effective retrofitting of pumped storage. The technology will be validated with detailed LCA and by consideration of CAPEX and OPEX of potential future plant. The 1st innovation is based on unique design solutions for a retrofittable reversible pump turbine technology enabling a cost-effective solution free of cavitation, enhanced flexibility, and reduced losses. The 2nd innovation is enabled by digital twins including hydraulic and sediment dynamics for pumped-storage. These tools give detailed information about the status of the current storage increasing the availability and robustness of the mechanical storage of electricity in existing RoR and RtR systems adapting to, for example, predictions of generation of intermittent electricity from wind and solar. Practically this will imply new storage of electricity in existing reservoirs and river stretches.

Keywords: storage of electricity,hydropower,pumped storage,innovation,retrofittable pump turbine,digital twin,lca,capex,opex,untapped hydropower,public acceptance,environment,eneegy system