Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Investigation into the Biological Cost and Adaptation of the Host to Antibiotic Resistance on mobile Genetic Elements in Enterococcus species (BIOCHARGE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2012-06-06
End date: 2014-06-05
Duration (months): 24.0
Total project cost (EUR): 210092.8
EU funding (EUR): 210092.8
Participants: 1
Project status: CLOSED

Conjugative transposons (cTns) are mobile genetic elements that mediate the transfer of antibiotic resistance to a wide range of bacteria including enterococci. Preliminary data revealed that the cTns, Tn6000, confer negligible burden or biological cost on enterococcal hosts. Our hypothesis is therefore: cTns have evolved regulatory mechanisms that can minimize their transcription. This leads to minimal biological cost to the host cell and stability of the mobile element within the population, explaining why they persist in bacteria from environments without selective pressure. In addition, we hypothesize that when two or more elements are in the same cell they may recombine to form a single element, again reducing their biological cost and ensuring their propagation. The aims of the project are: to determine if the cTns isolated from E. faecalis affect the fitness of their host and to test the hypothesis that the transcriptional regulation of these mobile elements determines their stability and persistence. Additionally, to determine if different elements can recombine in vivo, potentially forming new, more fit mobile elements and contributing to the evolution of antibiotic resistance development in pathogens. Experimental approach: The stability of the cTns and their recombination potential in enterococci will be assessed in the presence and absence of selective pressure (antibiotics). The absolute and relative fitness of the cTn containing strains will be evaluated and any compensatory mutations in the host will be determined by high throughput sequencing technologies and whole transcriptome shotgun sequencing. Mutagenesis of the regulatory region within the cTns will be carried out to understand the impact on stability of the element and fitness upon the host and to determine if this influences intracellular recombination and the evolution of the mobile elements.

Keywords: antibiotic resistance,bacteriology,molecular evolution,molecular biology
Biocontrol and Bioremediation agents and their role in Agriculture and Forest health (BIOREGENT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,Italy,Portugal,Sweden
Call:  (FP7-PEOPLE-2009-IRSES, 2009)
Start date: 2011-03-01
End date: 2014-02-28
Duration (months): 36.0
Total project cost (EUR): 57600.0
EU funding (EUR): 57600.0
Participants: 4
Project status: CLOSED

BioReGent brings together six centres and universities specialised in the area of improvement of forest and agro ecosystems by means of bioremediation and biological control agents. This network covers a unique set of competencies, expertises, infrastructures and training possibilities. The overall objective of this proposal is the establishment of a small network of specialised scientists from both the EU and Canada. This network will be focused on developing a more detailed fundamental understanding of how certain beneficial soil bacteria and fungi can facilitate the growth and development of plants. Concomitant with understanding the mechanisms involved in the microbial promotion of plant and tree growth, members of the network will develop and test schemes that are of practical (and possibly also commercial) interest in agriculture, horticultural, silviculture and environmental cleanup (i.e., phytoremediation). In our experience, effective collaboration which includes a true synergism, exchange of ideas and learning from one another is generally dependent upon good personal relationships between the collaborators – many members of the consortium have cooperated with each other with each other successfully in the past. We hope that the planned exchanges will foster a long term collaborative relationship between our groups, and teach our students a variety of new skills, approaches and ways of thinking. The ultimate goal of BioReGent is to deliver more effective treatments to diseases and pollution of forest and agro ecosystems, according to the actual philosophy in the European context of preservation of the ecosystems. The dynamic research program in an area of great demand offers outstanding training opportunities for future careers of the young researchers.

Keywords: agro-forestry,sylviculture,soil ecology,mycology,plant growth,plant nutrition,soil remediation,soil fertility,soil biodiversity
Stellar Astrophysics, Helioseismology, Asteroseismology and Nucleosynthesis (SAHA-NUC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-09-01
End date: 2013-08-31
Duration (months): 36.0
Total project cost (EUR): 75000.0
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Observational stellar astronomy has developed very quickly over the last decade, thanks to increased quality and quantity of observations, and also to the generalization of observational techniques such as interferometry and asteroseismology. While stellar astronomy has entered this “precision era”, theoretical models lag behind in their development and are not able to provide answers to questions raised by the new generation of observations, e.g. the “solar abundance problem”, mixing processes in stellar interiors, abundance patterns in metal poor stars, transport of angular momentum in stars, fundamental parameters of low-mass stars to mention some. Furthermore, neutrino experiments (e.g. Borexino at Gran Sasso) and asteroseismology with the recently launched Kepler mission will soon provide new observational probes of stellar interiors. Improved and more precise theoretical stellar models are therefore of high priority for advancing our understanding of stellar astrophysics and influenced areas, from galactic chemical evolution to formation of planetary systems. We propose to develop a new generation of stellar models by improving both the physics in the models and the modeling techniques. The proposal focuses on three targets: solar structure, stellar structure and asteroseismology, and structure and nucleosynthesis of low- and intermediate-mass stars. Development of models will be guided by existing and oncoming observational data, including solar neutrinos and asteroseismology (Kepler). The present proposal reinforces other European efforts related to solar and stellar physics, like the solar neutrino experiment Borexino, the Kepler Asteroseismic Scientific Consortium (hosted by Aarhus University), and HELAS initiative, funded as a “Co-ordination Action” under FP6. The grant will allow an internationally recognized scientist to establish himself as an independent researcher in Spain, bringing new expertise and network of collaborators to the European Union.

Keywords: physical sciences. sun: solar structure,neutrinos,composition,helioseismology,stars: structure,oscillations,asteroseismology,stars: late phases of evolution,nucleosynthesis
Quantum Repeaters for Long Distance Fibre-Based Quantum Communication (QUREP)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: Switzerland,Sweden,France,Germany
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2013-06-30
Duration (months): 42.0
Total project cost (EUR): 2481878.0
EU funding (EUR): 1900000.0
Participants: 5
Project status: CLOSED

The goal of QuRep is to develop a Quantum Repeater - the elementary building block required to overcome current distance limitations for long-distance quantum communication. Quantum Repeaters are the analogue of classical optical amplifiers that permit the cascading of successive fibre optic communication links. Quantum Repeater technology is centred around quantum light-matter interactions at the quantum level in ensembles of rare earth ions frozen in a crystal that store quantum information by coherent control of the quantum degrees of freedom. A clear and well-defined architecture and protocol for a complete Quantum Repeater can be realised with entangled photon pair sources that couple the Quantum memories to fibre optic communication systems. The proof of principle has been shown for all aspects of this approach and QuRep now aims to bridge the gap between fundamental research and industrial projects. The main technological result of the QuRep project will be a quantum repeater. The outcome of the QuREP project will serve as the basis for an industrial initiative, developing the first quantum repeater products. Considering the state of the art, potential difficulties and the chosen development approach, it is reasonable to assume that this technology could be translated into products in the next 10 years with spin-off technologies emerging in the interim period. We bring together the leading European groups in quantum communication, quantum memories, photonic sources and rare-earth-ion spectroscopy and materials as well as a leading quantum communication technology SME to move what has been fundamental research towards commercial feasibility. There are already niche markets for quantum repeaters, should they exist, and the market is expected to grow significantly in the next 10 years.

Keywords: quantum repeaters,quantum memories,quantum communication,qkd,quantum cryptography
NoE FlexNet - Network of Excellence for building up Knowledge for improved Systems Integration for Flexible Organic and Large Area Electronics (FOLAE) and its exploitation (FLEXNET)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Network of Excellence
Countries involved: Germany,France,Finland,Poland,Italy,Greece,Portugal,Italy,Spain,Romania,Poland,Czechia,Switzerland,Spain,Germany
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 4706043.0
EU funding (EUR): 4000000.0
Participants: 17
Project status: CLOSED

In the NoE FlexNet, 17 participants from eleven European countries work together in order to support Europe in becoming a world leader in Flexible, Organic and Large Area Electronics (FOLAE). FlexNet aims at interlinking Europe's FOLAE-expertise in the domains of science, technology development, components, devices and systems integration technologies. A special emphasis will be set on the subsequent commercial exploitation of FOLAE-based systems knowledge especially through SMEs, in order to enable a wide spread of FOLAE-based future business in Europe. The NoE FlexNet will support the integration process of the scientific excellence of FOLAE-oriented European research on Materials, Devices and Systems. This part is complementary to the NoE PolyNet efforts. In addition, FlexNet will integrate excellent scientific capacities from Southern and Eastern Europe. FlexNet partners have identified the organic transistor as the most crucial building block in order to realised integrated organic systems. Therefore, the scientific focus of the NoE FlexNet will be set on the application of FOLAE-specific organic semiconductors as well as supporting materials for OTFTs including research on interface properties, barrier materials, characterisation, and OTFT device integration into systems. Further topics of dedicated attention and activity will be devices characterisation, systems integration, modelling and design of systems, and manufacturing processes for systems. Accordingly, NoE FlexNet will be structured in three platforms: - A platform FOLAE Materials and Devices Integration, - A platform Systems Integration and - A platform Knowledge, Dissemination and Transfer to industry The knowledge associated to these topics will actively be made available to European stakeholders from research and industry, especially SMEs, in Southern and Eastern Europe. This will make FlexNet a bidirectional catalyst for information transfer in the FOLAE area between West-Central- and South-Eastern Europe. FlexNet will work in close contact with existing coordination actions in the FOLAE area like the Quadriga projects. This will ensure additional support in unifying and streamlining the fragmented FOLAE R&D arena in Europe.

Keywords: flexible,organic and large area electronics,printed electronics,eooe
Energy-conscious 3D Server-on-Chip for Green Cloud Services (EUROCLOUD)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: United Kingdom,Finland,Belgium,Switzerland,Cyprus,United Kingdom
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2013-06-30
Duration (months): 42.0
Total project cost (EUR): 5174086.0
EU funding (EUR): 3292000.0
Participants: 6
Project status: CLOSED

“Cloud Computing” refers to the emerging environment providing software and hardware services over the Internet or Cloud on demand. These services are provided to millions of Cloud users, in particular Mobile users, by thousands of servers in the data centres. Server power consumption and costs are becoming a great concern in the data centres in which the servers are built with high end, expensive and power-hungry CPUs. We are now reaching the limit of voltage scaling preventing further power reductions. In the absence of voltage scaling, chips in the future may have hundreds of cores, but to maintain a power envelope, these cores have to be embedded cores having orders of magnitude lower power consumption. Server applications are rich with client-request and memory-level parallelism. Each client is primarily served by a simple core with high-bandwidth/low-latency access to memory. 3D-stacking of on-chip DRAM on many embedded cores will provide high memory bandwidth with less power consumption while enabling scalability for green future servers. We propose EuroCloud - 3D “Server-on-Chip” built using many ARM cores and integrating 3D DRAM to provide a very dense low power server, and targeting the Cloud workloads. EuroCloud targets 10x improvement in cost- and energy-efficiency compared to current state-of-the-art servers. This will scale to hundreds of cores in a single server, and make a 1M core data centre feasible in the future. Thus, designing the 3D Server-on-Chip will provide us with capabilities to build super-efficient, environmentally clean and compact data centres in Europe aiming at green Cloud services. Thus, pioneering the green data centres will further strengthen the European leadership and excellence in green computing.

Keywords: cloud computing
Electrowetting Dynamics (EWETDYNAM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2009-11-01
End date: 2012-10-31
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

This proposal is concerned with electrowetting, which is a surface wetting phenomenon resulting from the electrical control of the surface tension properties on application of an electric potential. In recent years, the control of aqueous droplets on dielectrically insulated has become a hot topic. On the one hand, there are applications of electrowetting in electrical displays, auto-focus liquid lenses for mobile phones and video-speed smart paper. On the other hand, it offers many exciting applications for microfluidic systems for lab-on-a-chip devices to move, split, merge, and mix liquid droplets. The objective of the proposed research is to improve the performance of electrowetting in microfluidic systems for application to the pipe based bioreactor system that has been developed at the host institute. This improved performance is to be achieved by improved material choice for insulating and hydrophobic layers and a deeper study of how the interfacial properties of various materials affect the electrowetting dynamics.

Keywords: electrowetting,materials engineering,lab-on-a-chip systems,physical chemistry
Structural and Functional Analysis of Photosystem 2 from Nicotiana tabacum (SFAP2)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-05-03
End date: 2013-05-02
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

Water-splitting photosynthesis also known as oxygenic photosynthesis is a process whereby light energy is converted to chemical energy in membrane-bound pigment protein complexes located in the thylakoid membranes of higher plants and algae. Photosystem II (PSII) is one of the membrane protein complex involved in the photosynthetic process and it is characterized by a dual function: the capture of the light and the splitting of the water molecule. More in detail, PSII uses the electrons delivered during the water splitting for storing in a form of chemical energy the light energy absorbed from the protein complexes associated pigments. As a secondary product the atomic oxygen, produced from the splitting of the water, is converted to molecular oxygen and delivered to the atmosphere. Several structural and functional features of this pigment protein complex from higher plants are not completely understood. In order to address several questions, related with the function and the structure of PSII from higher plants, a fast and stable protocol of purification was developed and also a protocol of crystallization of PSII has been created. At moment the quality of the crystals needs to be improved in order to get them suitable for definitive structural and functional studies.

Keywords: photosynthesis,photosystem ii,x-ray crystallography,oxygen evolving complex,tobacco
Towards Electronic Product Coding with RFID tags based on hybrid organic-oxide complementary thin-film technology (ORICLA)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Components, systems, engineering
Action type: Collaborative project
Countries involved: Belgium,Germany,Netherlands,Germany
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 4699101.0
EU funding (EUR): 3015000.0
Participants: 5
Project status: CLOSED

ORICLA will be the world’s benchmark for RFID performance with Organic and Large Area Electronics, OLAE. RFID is an important technology e.g. in logistics, to transmit an identification code by radio waves (at high frequency (HF) or ultra-high frequency (UHF) between a transponder and a reader. The Electronic Product Code (EPC) protocol has been developed for use in high volume RFID logistic applications. EPC tags are widely used today on pallet level, and will later be used for packages and ultimately on item level. Such tags could also capture and transmit information on the environment (e.g. temperature) of the object of which they carry the identification. Thus, they will enable the vision of creating smart objects. OLAE technologies have key assets to capture large markets in this business: they allow to strongly reduce cost compared to Si chips, and simultaneously offer true mechanical flexibility, required for integration of tags onto items. Today OLAE RFID tags are limited in performance. The ORICLA partners will realize new OLAE chip technologies, based on complementary logic with organic and oxide semiconductors and on self-aligned imprint lithography as upscaleable patterning technology that can provide suitable dimensions. This unique combination will lead to demonstration of OLAE chips and tags with EPC-like performance, in particular showing: (i) bi-directional communication (i.e. the tag can understand and talk to the reader); (ii) EPC-compatible bit rates of 25 kbit/s; (iii) the first UHF (867 MHz) OLAE tags. The partners of the project are uniquely placed to realize these ambitious challenges. POLYIC is the first company, which demonstrated RFID tags produced by roll to roll printing. EVONIK develops unique oxide semiconductor materials. IMEC and TNO recently made the OLAE chip with the largest memory (128 bits) and a rectifier working at ultrahigh frequency.

Keywords: organic electronics,large area electronics,transponder,rfid,oxide semiconductor,self-aligned imprint lithography,electronic product code,thin-film transistor technology
The Medical Ecosystem - Personalized Event-based Surveillance (M-ECO)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Towards sustainable and personalised healthcare
Action type: Collaborative project
Countries involved: Germany,Denmark,Czechia,Austria,Germany,European organisations area
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2012-08-31
Duration (months): 32.0
Total project cost (EUR): 2591967.0
EU funding (EUR): 1999999.0
Participants: 7
Project status: CLOSED

Many factors in today’s changing societies contribute towards the continuous emergence of infectious diseases. Demographic change, globalization, bioterrorism, compounded with the resilient nature of viruses and diseases such as SARS and avian influenza have raised awareness for European society’s increasing vulnerability. Traditional Epidemic Intelligence systems are designed to identify potential health threats, and rely upon data transmissions from laboratories or hospitals. They can be used to recognise long-term trends, but are limited in several ways. Threats, such as SARS, can go unrecognised since the signals indicating its existence may originate from sources other than the traditional ones. Second, a critical strategy for circumventing devastating public health events is early detection and early response. Conflictingly, the time with which information propagates through the traditional channels, can undermine time-sensitive strategies. Finally, traditional systems are well suited for recognising indicators for known diseases, but are not well designed for detecting those that are emerging. Faced with these limitations, traditional systems need to be complemented with additional approaches which are better targeted for the early detection of emerging threats. The Medical EcoSystem (M-Eco) project, will address these limitations by using Open Access Media and User Generated Content, as unofficial information sources for Epidemic Intelligence. This type of content has transformed the manner in which information propagates across the globe. Based on this, M-Eco will develop an Event-Based Epidemic Intelligence System which integrates unofficial and traditional sources for the early detection of emerging health threats. M-Eco will emphasize adaptivity and personalized filtering so that relevant signals can be detected for targeting the needs of public health officials who have to synthesize facts, assess risks and react to public health threats.

Keywords: public health event detection,personalization,user generated content