Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A decision support system for self-management of low back pain (selfBACK)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: Research and Innovation actions
Countries involved: Norway,France,Netherlands,Denmark,United Kingdom,United Kingdom,Denmark
Call: Self management of health and disease and decision support systems based on predictive computer modelling used by the patient him or herself (H2020-PHC-2015-single-stage, 2015)
Start date: 2016-01-01
End date: 2021-03-31
Duration (months): 63.0
Total project cost (EUR): 4920872.5
EU funding (EUR): 4920872.5
Participants: 8
Project status: CLOSED

The recent global burden of disease study showed that low back pain (LBP) is the most significant contributor to disability in Europe. Most patients seen in primary care with LBP have non-specific LBP (≥85%), i.e., pain that cannot reliably be attributed to a specific disease/pathology. LBP is the fourth most common diagnosis seen in primary care (after upper respiratory infection, hypertension, and coughing). Self-management in the form of physical activity and strength/stretching exercises constitutes the core component in the management of non-specific LBP; however, adherence to self-management challenging due to lack of feedback and reinforcement. This project aims to develop a decision support system - SELFBACK - that will be used by the patient him/herself to facilitate, improve and reinforce self-management of LBP. Specifically, SELFBACK will be designed to assist the patient in deciding and reinforcing the appropriate actions to manage own LBP after consulting a health care professional in primary care. The decision support will be conveyed to the patient via a smartphone app in the form of advice for self-management. The advice will be tailored to each patient based on the symptom state, symptom progression, the patients goal-setting, and a range of patient characteristics including information from a physical activity-detecting wristband worn by the patient. The second part of the project will evaluate the effectiveness of SELFBACK in a randomized controlled trial using pain-related disability as primary outcome. We envisage that patients who use SELFBACK will have 20% reduction in pain-related disability at 9 months follow-up compared to patients receiving treatment as usual. Process evaluation will be carried out as an integrated part of the trial to document the implementation and map the patients’ satisfaction with SELFBACK. A business plan with a targeted commercialisation strategy will be developed to transfer the SELFBACK technology into the market.

Keywords: prevention,low back pain,self management,decision support system,physical activity
A Global Approach to Paid Domestic Work and Social Inequalities (DomEQUAL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Italy
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-09-01
End date: 2021-05-31
Duration (months): 57.0
Total project cost (EUR): 1199976.0
EU funding (EUR): 1199976.0
Participants: 1
Project status: CLOSED

How does globalisation impact the construction of social inequality? DomEQUAL tackles this question through a study on paid domestic work (PDW). Of the 52.6 million PDWs in the world today, 43 million are women and 7 million are children. The multidimensional transformations brought about by globalisation with the intensification of international migration, the urbanisation of rural and indigenous populations, and changes in household organisation and welfare regimes have a massive impact on PDWs at the global level. New research possibilities are open since PDW has become an object of global governance. The ILO Convention 189 is the most evident sign of this. For researchers, this has the important effect of making new data and tools for analysis available. DomEQUAL profits from this opportunity to provide a global comparison of PDWs’ social positions, especially in the socio-economic and legal fields. It also provides the opportunity to experiment an ‘intersectionality’ approach to PDW on a large scale. Finally, it analyses which type of global/local actor is more effective in improving the legal framework for PDWs. In so doing, it aims at a theoretical and methodological contribution that goes beyond PDW and addresses the construction of social inequalities within globalisation more generally. This is done through a diachronic comparison (1950s-now) of the changing situation of PDWs in the following countries: Spain, Italy and Germany in Europe; Colombia, Ecuador and Brazil in South America; and India, the Philippines and Taiwan in Asia. These nine countries are interesting cases for comparison because of their different positions within the process of globalisation, the specificities of their socio-cultural contexts, and also because they have all experienced mobilisations for PDWs’ rights. The project will be carried out by the PI and two senior post-doc researchers based in Italy, with the support of nine experts in the selected countries.

Keywords: domestic work,intersectionality,gender studies
Research Social platform On Migration and Asylum (ReSOMA)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Coordination and support actions
Countries involved: Italy,Belgium,Netherlands
Call: Research Social Platform on Migration and Asylum (H2020-SC6-REV-INEQUAL-2017, 2017)
Start date: 2018-02-01
End date: 2020-03-31
Duration (months): 26.0
Total project cost (EUR): 1999621.25
EU funding (EUR): 1999621.25
Participants: 9
Project status: CLOSED

This project will achieve regular collaboration between Europe’s well-developed networks of migration researchers and stakeholders for the purpose of evidence-based policymaking. As a result, European coordination on migration will be better informed of and more responsive to the recent migration dynamics and their diverse consequences. ReSOMA aims • for sustainable and mutually beneficial relationships for researchers and stakeholders to consult and work with each other more regularly in their ongoing work to inform EU public debates • to make the EU’s platforms for policy dialogue and consultation more evidence-based • to raise new evidence-based top priorities for the EU’s policy agenda A clear collaborative structure and toolbox will enable inter-disciplinary and multi-stakeholder analysis and policy dialogue with some of the most influential EU policymakers at EU and national level. Researchers will be able to put forward their robust scientific evidence and recognised authority in their field, while stakeholders will provide their complementary expertise with on-the-ground know-how and front-line experience. They are also well-positioned to secure attention from policymakers and allies from diverse sectors of society. In this collaboration, EU think-tanks will play a bridging role to combine the academic and practical expertise. They will also work alongside them to translate their evidence into ready-to-use policy briefs, recommendations and convincing messages and framings. In the end, the project will produce activities and deliverables that are both amplifying the voice of researchers and stakeholders in EU policymaking and tailored to the needs and constraints of EU and national policymakers. With the newly created tools and relationships, the project’s partners are exceptionally well-placed to enhance the role of the migration sector and research community in EU policymaking.

Keywords: asylum,integration,policy recommendation,coordination between research,stakeholders and policy makers
Transforming Intangible Folkloric Performing Arts into Tangible Choreographic Digital Objects (Terpsichore)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria,Germany,Cyprus,Greece,Greece,Lithuania,France,Czechia,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2015, 2015)
Start date: 2016-04-01
End date: 2020-03-31
Duration (months): 48.0
Total project cost (EUR): 1845000.0
EU funding (EUR): 1845000.0
Participants: 12
Project status: CLOSED

Intangible Cultural Heritage (ICH) content means "the practices, representations, expressions, knowledge, skills – as well as the instruments, objects, artefacts and cultural spaces associated therewith". Although, ICH content, especially traditional folklore performing arts, is commonly deemed worthy of preservation by UNESCO (Convention for the Safeguarding of ICH) and the EU Treaty, most of the current research efforts are on the focus is on tangible cultural assets, while the ICH content has been overlooked. The primary difficulty stems by the complex structure of ICH, its dynamic nature, the interaction among the objects and the environment, as well as emotional elements (e.g., the way of expression and dancers' style). TERPSICHORE aims to study, analyse, design, research, train, implement and validate an innovative framework for affordable digitization, modelling, archiving, e-preservation and presentation of ICH content related to folk dances, in a wide range of users (dance professionals, dance teachers, creative industries and general public) . The project targets at integrating the latest innovative results of photogrammetry, computer vision, semantic technologies, time evolved modeling, combined with the story telling and folklore choreography. An important output of the project will be a Web based cultural server/viewer with the purpose to allow user’s interaction, visualization, interface with existing cultural libraries (EUROPEANA) and enrichment functionalities to result in virtual surrogates and media application scenarios that release the potential economic impact of the ICH. The final product will support a set of services such as virtual/augmented reality, social media, interactive maps, presentation and learning of European Folk dances with tremendous impact on the European society, culture and tourism

Keywords: intangible cultural content,dances,digitalization,3d modeling,reconstruction,semantic information
Stakeholder community for once-only principle: Reducing administrative burden for citizens (SCOOP4C)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Innovative societies
Action type: Coordination and support actions
Countries involved: Estonia,Germany,Austria,Germany,Greece
Call: Co-creation between public administrations: once-only principle (H2020-SC6-CO-CREATION-2016-2, 2016)
Start date: 2016-11-01
End date: 2019-04-30
Duration (months): 30.0
Total project cost (EUR): 992480.0
EU funding (EUR): 992480.0
Participants: 5
Project status: CLOSED

Emerging challenges of demographic change and of digitisation of societies call for new innovative models of public governance. Citizens and other civil and private sector actors take a more active and responsive role in ensuring prosperity, a secure living environment and economic growth. Involving citizens in co-creation of public services while reducing administrative burden has become an important social and economic asset in innovative public governance. To significantly reduce administrative burdens, the once-only principle (OOP) demands public administrations to request key data of citizens and businesses only once, and to internally share these data, while respecting data protection and privacy regulations. However, this principle also bears a number of organisational, legal, socio-economic and technical challenges to finally harvest the full benefits and to reach the digital by default status. SCOOP4C will investigate, discuss and disseminate how the OOP can be implemented in public service provisioning in order to significantly reduce administrative burden and simplify administrative procedures for citizens while reusing data among public administration with the control and consent of citizens. In particular, SCOOP4C will (1) build up and sustain a stakeholder community; (2) identify, collect and share existing good practices of once-only implementations for citizens and establish a body of knowledge; (3) discuss challenges, needs and benefits of the OOP in co-creation and public service provisioning contexts involving citizens; (4) develop policy recommendations towards a necessary paradigm change to build trust in the once-only implementations; (5) identify relevant stakeholders and develop a strategic stakeholder engagement plan to ensure sustainable implementations of the OOP achieving wide outreach; and (6) develop a tangible roadmap of areas of actions for R&I to implement, diffuse and sustain implementations of the OOP.

Keywords: administrative burden reduction,stakeholder community for once only principle,stakeholder engagement plan,roadmap of areas of actions,policy recommendations for oop implementations
Validation of a personalised medicine tool for Multiple Myeloma that predicts treatment effectiveness in patients (MMpredict)

Framework: Horizon 2020 — Societal Challenges
Action type: Innovation actions
Countries involved: Italy,Belgium,Netherlands
Call: Fast Track to Innovation Pilot (H2020-FTIPilot-2015-1, 2015)
Start date: 2016-11-01
End date: 2020-10-31
Duration (months): 48.0
Total project cost (EUR): 3755802.5
EU funding (EUR): 2949027.5
Participants: 5
Project status: CLOSED

The consortium aims to commercialise the MMpredictor as a personalised medicine tool that predicts the most effective treatment strategy for individual Multiple Myeloma (MM) patients. MM is the second most common form of blood cancer contributing to 15% of all blood cancers and ~1,5% and 2% of all cancer deaths annually in the EU and US, respectively. Patients show a large variability in treatment response and side effects due to tumour heterogeneity and the patient’s intrinsic characteristics. Therefore, not every treatment will be suitable for each patient, and treatment strategies are often based on trial-and-error. The availability of multiple (>20) treatment options complicates treatment decision-making even more. With the current development of many more promising treatments, there is an urgent unmet clinical need for a diagnostic assay that supports personalised cancer treatment in order to improve patient health outcomes, prevent side effects and reduce healthcare costs. SkylineDx has previously developed the MMprofiler, a microarray-based diagnostic test that can subtype MM patients and reliably predict MM patient survival (prognosis). In this project, the test’s clinical value will be expanded to include the prediction of treatment effectiveness in individual patients based on Gene Expression Profiling. An addendum for new intended use will be filed to the current in vitro diagnostic (IVD) registration, while renaming the test to MMpredictor. The project will also focus on positioning the test as a cost-effective IVD test for personalised medicine, that will increase health outcome and quality of life of patients and reduce healthcare costs. The consortium consists of a life science SME specialised in molecular diagnostics, clinical centres with world renowned KOLs, a leading health economic institute, and a European MM patient advocacy organisation combining all the required complementary expertise to successfully bring the MMpredictor to market.

Keywords: personalised medicine,in vitro diagnostic test,multiple myeloma,biomarkers,prediction of treatment response
The world's first purpose-built professional all-terrain passenger Vehicle (ISAR)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Iceland
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-08-01
End date: 2017-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Tour operators and rescue services, operating in difficult conditions worldwide, need efficient passenger vehicles for their operations. However, today, no purpose-built on/off-road passenger vehicle is available that provides a combination of high performance, energy efficiency, passenger comfort and cost optimization. Current vehicles used for 7-21 passenger transportation and rescue in difficult, off-road conditions are highly-modified vans, SUVs and lorries. Modifying these vehicles with the necessary large tyres, extra fuel tanks, gear boxes and suspension systems is a time-consuming, costly and specialist task, and even the best of these modifications have significant drawbacks. We are Jakar, an all-terrain passenger vehicle manufacturer based in Iceland and our objective is to combine four decades of unique local knowledge into a pioneering modular vehicle solution. After years of close collaboration with tour operators and rescue teams, we have systematically identified and eradicated the design flaws of modified vehicles. Our new vehicle concept, Ísar, will be the world’s first purpose-built, EU-regulation-compliant, multi-passenger, high-performance vehicle for all terrain. We estimate the total global market opportunity for these vehicles is 10,000 units per year for use in tourism, Search and Rescue (SAR), and utilities. Ísar is a purpose-built vehicle that is made-to-order in modular sizes to carry up to 21 passengers. It will reduce operator seat-mile cost by up to 40%, yet is uniquely designed to deliver world-leading passenger comfort in any condition. Operators worldwide will have a purpose-made alternative to costly, compromised modifications. We already have 30 companies interested in purchasing our vehicle, and by 2025 we expect to have sold 102 Ísar vehicles globally, resulting in a combined revenue of €40.8 million.

Keywords: all terrain vehicle,off road,passenger vehicle,rescue,tourism,performance,road regulations
The Interstellar Medium of High Redshift Galaxies (INTERSTELLAR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Italy
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-10-01
End date: 2024-03-31
Duration (months): 78.0
Total project cost (EUR): 2151875.0
EU funding (EUR): 2151875.0
Participants: 1
Project status: SIGNED

When and how did the first galaxies form across cosmic history? Were they different from present-day ones? This is only a small subset of key cosmological questions that the combination of deep galaxy observations, theoretical modeling, and powerful simulations envisaged here will allow us to answer for the first time. Deep galaxy surveys have provided a first valuable characterization of early galaxies in the Epoch of Reionization (redshift z > 6), mostly in terms of their stellar content. However, almost nothing is known about their internal structure and Interstellar Medium (ISM). This is in striking contrast with galaxies at z < 2, for which ISM observations have enabled a much more complete physical description. Hence, a substantial progress in the study of early galaxies must be based on techniques able to probe their ISM. Conversely, ISM studies will help completing the “stellar” picture. Interstellar will bridge this gap. Its main aim is to understand the internal structure and interstellar medium of galaxies in the Epoch of Reionization by performing theoretical modeling and high fidelity simulations. By post-processing the simulations and calibrating them with local analogs, we will produce mock images/spectra used to (i) interpret available high-redshift observations, and (ii) plan breakthrough experiments with ALMA, JWST and E-ELT. The advent of ALMA, JWST, E-ELT and advances in computational cosmology make the study of high-z ISM one of the most promising areas of development in cosmology. The aim will be achieved through 5 objectives distributed among 3 Work Packages (WPs). WP1 is concerned with theoretical work, a preparatory phase for the cosmological simulations performed in WP2. WP2 represents the production phase of the project and will deliver cutting-edge zoom simulations of a sample of high-z galaxies and their ISM. Finally, WP3 is concerned with the exploitation of the numerical results and their integration with observations.

Keywords: high redshift galaxies,alma observations,jwst observations,cosmic reionization
A novel online service to support self-care and responsible self-medication (MEDimprove)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: SME instrument
Countries involved: Portugal
Call: Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-11-01
End date: 2017-04-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

People often use over-the-counter (OTC) medicines to treat minor health problems and see these medicines as safe. Yet, like any other, OTC medicines present risks and can cause significant morbidity and mortality. To minimize these problems, the decision to self-medicate must take into account all patient's characteristics and relevant medicine information. Despite the risks, self-medication is an increasing practice worldwide and OTC medicines are easily available in stores and for online sale, without counselling from a healthcare provider, in EU and USA. In this global context, we created MEDimprove, a web platform for patients that supports responsible self-care and self-medication. The software is a clinical decision support system based on a complex algorithm that integrates all relevant patient and medicine variables and suggests the adequate safe treatment for each patient. It provides health information and personalized health counselling in a convenient, user-friendly and confidential environment. By integrating with online medicine stores, MEDimprove also gives the possibility to buy OTC medicines and other health products. For these stores, MEDimprove will increase sales by providing users with a professional and personalized counselling. Patients have free access to MEDimprove. Revenues come from: sales fees from pharmacies/medicine stores and advertising from pharmaceutical companies. We expect revenues of nearly 1.9 million euros in 3 years in a growing market of online OTC and dermocosmetics sales (which represent 15% of all online shopping and annual CAGR of the EU Market above 8%). We founded serFarma in 2014, providing innovative pharmaceutical services aiming to increase patients’ quality of life by using technology to promote the adequate use of medicines. We have invested over 150.000€ of own funds, and have started having revenues in March 2016.

Keywords: self care,self medication,minor health problems,otc medicines,health products,clinical decision support system,online sales