Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Quasiconformal Methods in Analysis and Applications (QUAMAP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Spain,Finland
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-09-01
End date: 2025-08-31
Duration (months): 72.0
Total project cost (EUR): 2280350.0
EU funding (EUR): 1107138.75
Participants: 4
Project status: SIGNED

The use of delicate quasiconformal methods, in conjunction with convex integration and/or nonlinear Fourier analysis, will be the common theme of the proposal. A number of important outstanding problems are susceptible to attack via these methods. First and foremost, Morrey's fundamental question in two dimensional vectorial calculus of variations will be considered as well as the related conjecture of Iwaniec regarding the sharp $L^p$ bounds for the Beurling transform. Understanding the geometry of conformally invariant random structures will be one of the central goals of the proposal. Uhlmann's conjecture regarding the optimal regularity for uniqueness in Calder\'on's inverse conductivity problem will also be considered, as well as the applications to imaging. Further goals are to be found in fluid mechanics and scattering, as well as the fundamental properties of quasiconformal mappings, interesting in their own right, such as the outstanding deformation problem for chord-arc curves.

Keywords: vectorial calculus of variations,quasiconformal geometry,holomorphic motions,nonlinear fourier analysis,calder n s inverse problem,convex integration,chord arc curves,conformal invariance,dimer models
Imaging-XChem: A computational package for ultrafast electronic control in chemistry (Imaging-XChem)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2017-11-01
End date: 2019-04-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Commercial quantum-chemistry computational packages are widely used in science and chemical industry to predict the properties and reactivity of molecules and to design new compounds and drugs that can eventually be synthesized in the laboratory. The software developed in the framework of the ERC AdG project XCHEM is aimed at providing a full quantum mechanical description of a large variety of chemical processes that cannot be addressed by standard quantum chemistry packages, namely those processes in which molecular ionization takes place. An accurate description of molecular ionization is crucial to develop new applications and make reliable predictions in emerging scientific disciplines, such as attochemistry, single-molecule imaging, and coherent attosecond control of chemical reactions. As it happened with traditional quantum chemistry packages, there is now the need to produce a documented and friendly version of this newly developed software in order to facilitate its widespread use by other scientists, either theoreticians or experimentalists working at huge European infrastructures, and by private sector companies and other stakeholders. This project aims at providing a powerful tool to describe molecular ionization by attosecond laser pulses by transforming the outputs of the ERC AdG XCHEM project in a service-oriented software system. Main efforts will be directed to (i) document, optimize and test the codes under different architectures, (ii) implement a user interface in order to simplify its future use, (iii) explore different itineraries to ensure a proper exploitation of the product, and (iv) prepare training sessions and material to facilitate the incorporation of this new technology to less expert users.

Keywords: service oriented software,x ray free electron lasers,attosecond chemistry,time imaging of molecular changes,attosecond control of chemical reactions,radiation induced damage
Resonant Nuclear Gamma Decay and the Heavy-Element Nucleosynthesis (gRESONANT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Norway
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-03-01
End date: 2020-02-29
Duration (months): 60.0
Total project cost (EUR): 1443472.0
EU funding (EUR): 1443472.0
Participants: 1
Project status: CLOSED

THE GRAND CHALLENGE: The “Holy Grail” of nuclear astrophysics is to understand the astrophysical processes responsible for the formation of the elements. A particularly challenging part is the description of the heavy-element nucleosynthesis. The only way to build the majority of these heavy nuclides is via neutron-capture processes. Unaccounted-for nuclear structure effects may drastically change these rates. MAIN HYPOTHESIS: Nuclear low-energy gamma-decay resonances at high excitation energies will enhance the astrophysical neutron-capture reaction rates. NOVEL APPROACH: This proposal is, for the first time, addressing the M1 scissors resonance in deformed, neutron-rich nuclei and superheavy elements. A new experimental technique will be developed to determine the electromagnetic nature of the unexpected upbend enhancement. Further, s-process branch points for the Re-Os cosmochronology will be studied for the first time with the Oslo method. OBJECTIVES: 1) Measure s-process branch point nuclei with the Oslo method 2) Radioactive-beam experiments for neutron-rich nuclei searching for the low-energy upbend and the M1 scissors resonance 3) Develop new experimental technique to identify the upbend’s electromagnetic nature 4) Superheavy-element experiments looking for the M1 scissors resonance POTENTIAL IMPACT IN THE RESEARCH FIELD: This proposal will trigger a new direction of research, as there are no data on the low-energy gamma resonances neither on neutron-rich nor superheavy nuclei. Their presence may have profound implications for the astrophysical neutron-capture rates. Developing a new experimental technique to determine the electromagnetic character of the upbend is crucial to distinguish between two competing explanations of this phenomenon. Unknown neutron-capture cross sections will be estimated with a much better precision than prior to this project, and lead to a major leap forward in the field of nuclear astrophysics.

Keywords: nuclear gamma decay resonances,gamma ray strength function,nuclear experiments,stable beam,radioactive beam experiments,neutron capture reactions,astrophysical reaction rates
European Research Infrastructure for Science, technology and Innovation policy Studies 2 (RISIS 2)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Integrating activities and infrastructures
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Austria,Austria,Germany,Germany,Spain,Israel,Switzerland,Norway,Greece,France,France,Czechia,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: Integrating Activities for Advanced Communities (H2020-INFRAIA-2018-1, 2018)
Start date: 2019-01-01
End date: 2023-12-31
Duration (months): 60.0
Total project cost (EUR): 8492625.0
EU funding (EUR): 8492625.0
Participants: 22
Project status: SIGNED

The European Research infrastructure for science, technology and innovation policy studies (RISIS2) aims at building a data and services infrastructure supporting the development of a new generation of analyses and indicators. To develop a deeper understanding of knowledge dynamics and policy relevant evidence, the project goes beyond established quantitative indicators, developing positioning indicators, which take into account critical features of knowledge dynamics i.e. the importance of asymmetries in producers, in places and in themes. RISIS datasets are built keeping information on these three dimensions. To exploit them, new services dealing with actor identification, geographical information and thematic foci are developed, as well as semantic analytical capabilities. This project builds on RISIS1 (2014-18), which has demonstrated the relevance of such an approach and opened access to a first set of databases and services. RISIS2 gathers 19 partners aiming to transform the field of STI studies into an advanced research community. This step change is achieved by: (i) developing an e-infrastructure that supports full virtual transnational access by researchers, (ii) providing a vastly enlarged set of services tailored to field-specific needs (for problem-based integration of datasets, for exploring open data, and for supporting analytical capabilities of researchers), (iii) maintaining datasets dealing with firm innovation capacities, public research developments, R&I outputs and projects, and policy learning, (iv) developing new datasets on 4 key issues for research and policy (social innovation, non technological innovation, the role of PhDs in society, portfolios of public funding instruments). As reflected in the strong role of OpenAire in RISIS2, the infrastructure is fully inscribed into the open science movement. It is accompanied by a strong training, dissemination and communication effort to support the important widening of the community we aim at.

Keywords: science and technology,innovation,sti indicators,research and innovation policies,knowledge dynamics,public research,firm innovation capabilities
Understanding microbiomes of the ruminant holobiont (HoloRuminant)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Ireland,Ireland,Israel,Spain,Spain,Australia,Norway,Belgium,Lithuania,Finland,New Zealand,France,France,Netherlands,United States,Netherlands,Denmark,United Kingdom,United Kingdom,Canada
Call: Healthy terrestrial livestock microbial ecosystems for sustainable production (H2020-SFS-2020-2, 2020)
Start date: 2021-10-01
End date: 2026-09-30
Duration (months): 60.0
Total project cost (EUR): 10895021.0
EU funding (EUR): 9724763.75
Participants: 25
Project status: SIGNED

Sustainability of ruminant production is of concern to society because of its implications for the environment, the economy and food security. Microbiomes associated with the host play a key role in health, welfare and environmental efficiency in ruminant production systems. However, despite the information already available, we lack the insights to precisely link the causes and mechanisms of microbial influence on ruminant phenotypes. This is because the interconnection and communication between the animal and its different microbiomes have never been studied in a deep, integrated way. The goal of the project is to elucidate the role of ruminant-associated microbiomes and their interplay with the host in early life and throughout fundamental life events. HoloRuminant will use a holistic multi-omics approach to characterise the acquisition and evolution of microbiomes from different body sites, their inheritability and their influence on the host’s resistance to disease and environmental efficiency of production. Specifically we will: determine microbiomes’ functions by combining multi-level information for microbes, host and their interaction; define microbiomes’ roles during challenging life periods such as perinatal, weaning, and after exposure to pathogens; and evaluate the effect of ruminant microbiomes on critical phenotypes for sustainable production, health and welfare. This will allow the identification of novel microbial markers for monitoring, predicting and selecting phenotypes of interest. By engaging actors from the livestock value chain, we will evaluate the socio-economic impact and acceptability of the innovations proposed among stakeholders and the public. HoloRuminant will provide highly innovative, standardized methodologies that will radically advance our understanding of the ruminant holobiont. This knowledge and the tools created will allow the use of microbiome-based diagnostics and solutions for improving ruminant sustainabilty.

Keywords: cattle,small ruminant,microbiome,early life colonisation,performance indicators,sustainability,carbon footprint,microbial ecology
Automatic non-destructive recognition of used printing techniques on substrates (Andrupos)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Germany,Germany,Netherlands
Call: Critical infrastructure protection topic 7: SME instrument topic: “Protection of Urban soft targets and urban critical infrastructures” (H2020-SMEINST-1-2014, 2014)
Start date: 2015-04-01
End date: 2015-09-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 3
Project status: CLOSED

Identifying the source printer and the knowledge of distinctive printer and printing details of a document are a important steps in fighting crime like forgery or threathening letters. The evidence obtained from such printed documents analysis will provide useful forensic information to law enforcement, security and intelligence agencies. In this context, the objectives of our overall innovation project are to develop technologies for a software based, automated and non-destructive analysis of printed documents in terms of the identification of the utilised printing technology (like offset-, intaglio-, ink jet-, laser-, solid Ink- und thermal print, xerographie, magnetographie, liquid toner and other), for digital printing technlogies also the print engine and the printer brand and model or even serial number/specific printer. Documents in question will be banknotes, ID cards, stamps, tickets, contracts, tickets, bills, financial documents, threathening letters. With the knowledge of printing information of a single printed document different analysis use cases can be set up comprising also examinations of a set of documents like determining if all pages are printed with the same printer. With the help of the Andrupos system it will also be possible to link questioned documents to a single printer item and therefore it is the first system that has a tool to also link organized crime (they often use counterfeit id-documents, printed on the same source) in an earlier stage. This developed analysis software shall be integrated into a web based server system. Client applications on different types of devices (desktop pcs, mobile devices) then can post scanned (magnified) images sections of the documents in question via internet to the server. The server application receives the data, analyses the image and matches the extracted features with the database entries (printing technologies, printer brands, printer models, ..).

Keywords: automatic non destructive recognition of used printing techniques on substrates
MEFISTO - Meniscal functionalised scaffold to prevent knee Osteoarthritis onset after meniscectomy (MEFISTO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Italy,Germany,Israel,Italy,Italy,Germany,Belgium,Switzerland,Switzerland,France,Netherlands,Netherlands,United Kingdom
Call: Osteoarticular tissues regeneration (RIA) (H2020-NMBP-TR-IND-2018, 2018)
Start date: 2019-04-01
End date: 2024-05-31
Duration (months): 62.0
Total project cost (EUR): 5996590.0
EU funding (EUR): 5996590.0
Participants: 15
Project status: SIGNED

MEFISTO will develop two novel solutions to treat meniscus loss as a strategy for preventing the onset of an epidemic of post-meniscectomy knee osteoarthritis (OA) in Europe. Morphological profiling will identify the population of patients who, after meniscal resection, are at higher risk of early compartment degeneration, providing a personalized approach for the patient. The two different reconstructive strategies are: i) a controlled vascularized bioactive biodegradable meniscal scaffold, which will regenerate the native meniscus. This strategy will address younger patients with early osteoarthritic changes. ii) a bioactive non-biodegradable meniscal prosthesis, which will act as a mechanical unloading device and a drug delivery system, with the capacity to modulate the inflammatory environment. This strategy will address patients with advanced OA. A socio-economic analysis of the efficacy of existing meniscal substitutes will complete the project. This analysis is of vital importance for the European healthcare system, as it will provide a clear understanding of the costs and benefits of current clinical practice and predict the impact of the two new interventions. The technological innovation lies in the development of biologically active functionalized nanobiomaterials that can interact with the surrounding articular tissues. The biodegradable scaffold will promote revascularization in the peripheral zone, while leaving the inner zone avascular, reflecting the native meniscal tissue and functionalization with drug delivery micro/nanoparticles of the non-biodegradable device will provide modulation of inflammation. The impact is expected to be significant as so many patients have undergone or will undergo meniscectomy. The interventions developed in MEFISTO will prevent these patients from receiving joint-sacrificing procedures such as metal prosthesis whilst reducing the social burden, associated costs and high levels of morbidity resulting from OA.

Keywords: 3d biofunctionalisation,meniscus regeneration,personalized treatment algorithm,cost efficiency
GaN densily integrated with Si-CMOS for reliable, cost effective high frequency power delivery systems (GaNonCMOS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Research and Innovation actions
Countries involved: Ireland,Austria,Austria,Germany,Germany,Germany,Germany,Germany,Switzerland,Belgium,Belgium,Belgium,Netherlands
Call: Advanced Materials for Power Electronics based on wide bandgap semiconductor devices technology (H2020-NMBP-2016-two-stage, 2016)
Start date: 2017-01-01
End date: 2021-06-30
Duration (months): 54.0
Total project cost (EUR): 7428885.75
EU funding (EUR): 6246064.5
Participants: 15
Project status: CLOSED

Power electronics is the key technology to control the flow of electrical energy between source and load for a wide variety of applications from the GWs in energy transmission lines, the MWs in datacenters that power the internet to the mWs in mobile phones. Wide band gap semiconductors such as GaN use their capability to operate at higher voltages, temperatures, and switching frequencies with greater efficiencies. The GaNonCMOS project aims to bring GaN power electronic materials, devices and systems to the next level of maturity by providing the most densely integrated materials to date. This development will drive a new generation of densely integrated power electronics and pave the way toward low cost, highly reliable systems for energy intensive applications. This will be realized by integrating GaN power switches with CMOS drivers densely together using different integration schemes from the package level up to the chip level including wafer bonding between GaN on Si(111) and CMOS on Si (100) wafers. This requires the optimization of the GaN materials stack and device layout to enable fabrication of normally-off devices for such low temperature integration processes (max 400oC). In addition, new soft magnetic core materials reaching switching frequencies up to 200 Mhz with ultralow power losses will be developed. This will be assembled with new materials and methods for miniaturised packages to allow GaN devices, modules and systems to operate under maximum speed and energy efficiency. A special focus is on the long term reliability improvements over the full value chain of materials, devices, modules and systems. This is enabled by the choice of consortium partners that cover the entire value chain from universities, research centers, SME’s, large industries and vendors that incorporate the developed technology into practical systems such as datacenters, automotive, aviation and e-mobility bikes

Keywords: power electronics
An Automatic Microfluidic Device Assembly System (uDAS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Israel
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-04-01
End date: 2016-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Microfluidic systems, in general, have proven important platforms for biomedical assays. These systems benefit from reduced requirements for expensive reagents, short analysis times, and portability. Although microfluidic systems are convenient platforms, their use in the life sciences is still limited mainly due to the high-level fabrication expertise required for construction. Integrated microfluidics is one of the most sophisticated three-dimensional (multi layer) solution. It requires soft lithography (PDMS based chips), for production of high complexity microfluidic systems (multiple serial or parallel processes). Integrated microfluidics in particular is almost non-existent in the industry due to the low yield and uncontrolled production process. My ERC project (MUDLOC-2012) is to develop a microfluidic platform for multidimensional protein array analysis. It uses complex multilayer microfluidic devices that consist of 2 PDMS layers and a glass microarray. The integrated microfluidics system contains thousands of micromechanical valves in micrometer dimensions, controlling thousands of parallel reactions. Our research demands production of hundreds of such devices. We, as all others who produce integrated microfluidics, suffered from frustrating low yield (15%). In order to improve fabrication yield and to fabricate devices with increased density, we designed and manufactured, a first of its kind, full production process sequence, semi automatic Microfluidic Device Assembly System (µDAS). This resulted in a direct increase of device complexity and yield (85%) over the last half year. The 2nd generation automated µDAS prototype will become a generic assembly tool for soft lithography. µDAS will enable a critical production standard and process control, which will pave the road for significant penetration of complex integrated microfluidics technology into both academia and industry.

Keywords: integrated microfluidics,lab on chip,production process control