Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
CO2 - Loop for Energy storage and conversion to Organic chemistry Processes through advanced catalytic Systems (CEOPS)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: France,Portugal,Spain,France,Italy,Romania,Germany
Call:  (FP7-NMP-2012-SMALL-6, 2012)
Start date: 2013-02-01
End date: 2016-01-31
Duration (months): 36.0
Total project cost (EUR): 3508268.26
EU funding (EUR): 2662586.0
Participants: 10
Project status: CLOSED

CEOPS project will focus on a sustainable approach for the production of methanol from CO2, which is a precursor for fine chemicals products. The approach will reinforce the link between large CO2 emitters and fine chemical industries at the European level. The concept relies on two chemical pathways, CO2 to CH4 and CH4 to CH3OH with the intermediate carbon vector: methane. Methane benefits from the extended and existing natural gas network infrastructure. Its distribution will prevent additional CO2 emissions (rail & road transportation). This approach will favour the emergence of small and flexible production units of fine chemicals from methanol. The technological work is based on advanced catalysts and electro-catalytic processes. CEOPS will develop advanced catalysts for application in three promising electro-catalytic processes (Dielectric barrier discharge plasma catalysis, Photo-activated catalysis and Electro-catalytic reduction) to increase their efficiency overtime for both pathways. The performances of the studied catalyst and process schemes will be benchmarked and the most efficient one, for each pathway, will be selected for a prototype. This prototype will be realised at a scale of 3m3.h-1 of methane, it will validate the concept and generate the required data for the techno-economic assessment. The consortium merges the skills of 2 research organisations, 3 universities, 1 SME, 1 non profit organisation, 2 industries and 1 cluster. The project is led by CEA-LITEN. Italcementi, GSER and CCB will bring respectively their expertise in CO2 emissions, CH4 injection and transportation and on methanol use for the fine chemical industry. They also contribute to the techno-economic and environmental assessments. IST, IREC, OMNIDEA will develop advanced catalysts. UPMC, CEA, IREC, NOVA will develop electro-catalytic processes. CEA assisted by the consortium will implement the prototype. EMSR and CCB will ensure the dissemination of the CEOPS concept and results.

Keywords: valorisation,methane,methanol,catalysis,dbb,photocatalytic,photo-electro-catalytic processes,greenhouse gases,fien chemicals
Wind Blade Using Cost-Effective Advanced Composite Lightweight Design (WALID)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: Germany,United Kingdom,Netherlands,Netherlands,Norway,France,France,Cyprus,Denmark,Germany
Call:  (FP7-NMP-2012-SMALL-6, 2012)
Start date: 2013-02-01
End date: 2017-01-31
Duration (months): 48.0
Total project cost (EUR): 5499110.65
EU funding (EUR): 3964797.0
Participants: 15
Project status: CLOSED

WALiD will combine design, material and process developments using thermoplastic materials to create cost-efficient, lightweight and recyclable blades which will be demonstrated by industrial end-users. The power generated by off-shore wind turbines is proportional to the rotor plane area of the blade. However, the weight of large blades puts the materials used under considerable strain, leading to shorter operational life. Off-shore wind turbines operate under harsh conditions e.g. extreme temperatures, humidity & salt conditions. Despite these critical technical requirements for strength and stability, the materials must be cost-efficient and recyclable. The key innovation in WALiD is the introduction of thermoplastic composite materials and processing into wind blade applications. These materials can replace thermoset-based materials in the root, tip and shear web, leading to the following advantages: 1. Improved design of blade root, connection concept and tip: strain analysis on the blade will enable high-performance thermoplastic composites to replace thermosetting components, saving costs and weight. 2. Replacement of the shell core with thermoplastic foam materials: the density of the core material can be modified to the specific load, optimizing the weight/stability profile. Further cost and weight savings will result from processing (elimination of cutting process, no infiltration of resin into empty spaces). 3. Improved modular concept of shear web design: replacement of thermosets by thermoplastic composite structures to ensure lightweight, load-optimized design. 4. Development of fibre-reinforced thermoplastic coating, improving environmental resistance, anti-icing properties and durability against abrasion combined with a new predictive simulation model. Strong industrial participation (74% of the project budget) with an accompanying unfunded Industrial Exploitation Board will ensure the commercial relevance and exploitation of these developments.

Keywords: material,process developments,thermoplastic,lightweight,recyclable,wind turbines,offshore,cost-efficient
Integrated photonics for breath analysis (INBREATHE)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: Belgium
Call:  (ERC-2011-PoC, 2011)
Start date: 2012-09-01
End date: 2013-08-31
Duration (months): 12.0
Total project cost (EUR): 163700.0
EU funding (EUR): 149757.0
Participants: 1
Project status: CLOSED

We have developed an optical sensor platform that might fulfil the requirements of the ideal breath analysing device. Breath analysis is emerging as a valuable noninvasive clinical diagnostic tool. As an example, the detection of an elevated concentration of ammonia in human breath has the potential to probe kidney and liver malfunctions. The ideal breath monitoring device is one that is sensitive to the specific gas and capable of accurately detecting it at physiologically relevant concentrations in the ppb range, insensitive to interferences, can simultaneously measure multiple VOCs at different concentration levels, is portable and easy to use for point-of-care, displays real-time data and is low cost. The innovation of our idea is that we combine silicon photonics with a high surface area chemically selective coating to enable these requirements. Silicon photonics integrates optical components. Extreme miniaturisation, dense integration and high accuracy at low cost for optical applications are the key features of this technology. By coating miniature optical silicon photonics resonators with a microporous chemically selective silica film, we paved the way for sensitive, compact and inexpensive gas sensors. We have elaborated this idea for ammonia gas detection and have demonstrated that the detection is sensitive, selective, real-time and reversible. Here, we'll develop the essential conditions to start the early commercial stage to market a breath analyser.

Keywords: 267853
The Structure and Assembly of Membrane Proteins in Native Membranes studied by AFM (MEM-STRUCT-AFM)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Molecular and Structural Biology and Biochemistry
Countries involved: France
Call:  (ERC-2012-StG_20111109, 2012)
Start date: 2013-01-01
End date: 2017-12-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: CLOSED

One of the key characteristics of life is the existence of boundaries that delineate the organism from its environment. The boundary membrane structure that defines all cells is called the plasma membrane. Membranes are constituted of a large variety of lipids and membrane proteins, key molecules for plenty vital cellular functions such as transport, energy transduction, signaling, and communication, to name a few. Despite the importance of membrane processes, little is known about the structure of its constituents and less about their supramolecular arrangement. In this project the focus is set on the analysis of membrane proteins, their supramolecular complexes, their structural assembly and mechanism of cooperative function, and thus an integral view of the native membrane. To achieve this goal, we are performing membrane biochemistry and develop 3 axes of research, all Atomic Force Microscopy (AFM) –based, comprising technical developments of high-resolution and high-speed AFM, AFM-hybrid techniques, but also target-focused application research, all, to gain information about the structure and assembly of membrane proteins in native membranes at unprecedented resolution. 1) Technical developments: In this project subaxis, we are performing two major technical developments, a hybrid atomic force microscope (AFM) - tip enhanced raman spectroscopy (AFM-TERS), and a high-speed AFM - Optical Microscopy setup. 2) AFM imaging: Analysis of the supramolecular assembly of membrane complexes in native membranes ex cellula and in cellula, with a particular focus on alterations of membrane structure and membrane protein assembly and conformation due to pathology or addition of drugs. 3) AFM force spectroscopy: Analysis of forces and affinities within and in between membrane complexes on molecules and cells, with a particular focus on the development of small-cantilever HS-AFM -based force spectroscopy (dynamic force spectroscopy and force clamp modes).

Keywords: atomic force microscopy membrane protein membrane structure supramolecular assembly
Mapping canine genes and pathways to leverage personalized treatment options (K9GENES)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Genetics,Genomics,Bioinformatics and Systems Biology
Countries involved: Sweden
Call:  (ERC-2012-StG_20111109, 2012)
Start date: 2012-12-01
End date: 2017-11-30
Duration (months): 60.0
Total project cost (EUR): 1499365.0
EU funding (EUR): 1499365.0
Participants: 1
Project status: CLOSED

The domestic dog encompasses hundreds of genetically isolated breeds, many of which show an increased risk for certain diseases. With the canine genome sequence, an understanding of the haplotype structure and availability of disease gene mapping tools, we are now in a unique position to map canine disease genes to inform human biology and medicine. So far we have mapped monogenic traits as well as >40 loci for >10 complex traits. We now propose to map genes for key diseases using many breeds to dissect a larger number of genes underlying the specific disease. We further plan to evaluate the functional consequences of mutations and pilot personalized treatment strategies based on genetic risk. The specific aims are: 1.Characterization of disease phenotypes, breed predisposition and sample acquisition. We are currently collecting samples from >20 diseases and will expand our phenotypic classification and sample collection to a larger number of breeds for some key diseases such as osteosarcoma, breast cancer, behavior and atopy or lymphocytic thyroiditis. 2.Identification and functional characterization of canine disease genes and pathways. We will perform genomewide association mapping followed by targeted resequencing for mutation detection. Pathway analysis will be performed to understand the disease mechanisms mostly contributing to the disease. For select mutations, we will use state of the art molecular biology to provide detailed functional characterization of selected genes revealed by our gene discovery platform. 3.Piloting canine personalized treatment strategies based on inherited risk factors. For a few diseases we will pilot personalized treatment strategies based on inherited risk factors, utilizing the genetic information gathered in aim 2. Available or novel drugs acting on the identified pathways will be tested in dogs with specific risk factors using a veterinary network for clinical trials. Knowledge gained should inform human personalized medicine.

Keywords: genetics,genomics,behaviour,animal models,personalized medicine,genetic mapping,cancer
Indoor Dye Sensitized Solar Cells (IDSC)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: Switzerland
Call:  (ERC-2011-PoC, 2011)
Start date: 2012-07-01
End date: 2013-06-30
Duration (months): 12.0
Total project cost (EUR): 160400.0
EU funding (EUR): 148440.0
Participants: 1
Project status: CLOSED

Low power electronic devices are growing ever more omnipresent in the home and work environments. From digital music players, to cell phones, wireless keyboards, and hearing aids, the operation of all such devices requires available electrical power. Batteries are presently the dominant power source for these applications, however the fixed capacity requires periodic replacement or recharging. On the other hand, photovoltaic power sources continuously provide electrical power in lit environments. High power conversion efficiencies are key to enabling design flexibility by lowering the required surface coverage of devices. The tunable nature of dye sensitized solar cells (DSC) make them uniquely well fit to efficiently harvest indoor light. With this project we aim to demonstrate that DSCs are a competitive power source for the indoor environment. The unique ability to align the harvesting with the incident spectrum provides significant innovation potential for indoor DSCs. Demonstration of superior power conversion efficiency along with the requisite durability metrics will form a persuasive package to motivate additional investment. Drawing from concepts developed under the MESOLIGHT project (ERC grant 247404), the latest advancements in DSC designs will be employed to gain further advantages over competing technologies. Particularly, dye molecules and the corresponding electrolyte compounds designed and synthesized as part of MESOLIGHT task 1 will be utilized in the construction of DSCs for testing under indoor lighting conditions. These new cells are expected to demonstrate unprecedented power conversion efficiencies exceeding 20% under simulated indoor lighting. Beyond laboratory scale DSCs, we will further demonstrate enhanced indoor performance with an industrial DSC architecture based on flexible substrates.

Keywords: 247404
Rare Earth Magnet Recovery for Environmental and Resource Protection (REMANENCE)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Integration
Action type: Collaborative project
Countries involved: United Kingdom,Sweden,United Kingdom,Spain,Sweden,Germany,Slovenia
Call:  (FP7-NMP-2012-SME-6, 2012)
Start date: 2013-01-01
End date: 2016-06-30
Duration (months): 42.0
Total project cost (EUR): 4965983.65
EU funding (EUR): 3722000.0
Participants: 11
Project status: CLOSED

The REMANENCE concept is to develop new and innovative processes for the recovery and recycling of rare earth (RE) containing neodymium iron boron magnets (NdFeB) from a range of waste electronic and electrical equipment (WEEE). Advanced sensing and mechanical separation techniques combined with innovative processes based on hydrogen decrepitation will recover the rare earth magnets in the WEEE. Significantly with the REMANENCE concept, the aim will be to recover material in a form that can easily re-enter the primary magnet manufacturing production route, so providing large energy savings and production costs. There is no existing process for the recovery of NdFeB magnets from waste streams and this highly valuable material is lost to land fill with no prospect of commercial recovery. The material recovered in the REMANENCE concept will have a substantial economic value, which considering current virgin material costs, is estimated to be €80-120 per kg. If fully implemented REMANENCE will provide a secondary source of materials for the EU, large enough to supply the entire EU bonded magnet manufacturing industry and a significant proportion of the EU’s high value sintered magnet production. REMANENCE brings together Europe’s leading experts in; sensing, disassembly, recycling technology and materials processing with a group of innovative SMEs in a multi-disciplinary project able to deliver significant technical advances. The key technical roles of the SMEs as either equipment manufacturers (CTECH, OPTI, ABI) or direct end users of the recovered materials (MAG) will focus the project towards commercial outputs that will result in excellent exploitation opportunities for the developed processes.

Keywords: rare earth element recovery,recycling,sustainable technology,resource efficient technology,ndfeb magnet reprocessing,hydrogen decrepitation
Targeting the biological imaging market with multifunctional fluorescent nanoparticles (BIONLIGHT)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: Netherlands
Call:  (ERC-2011-PoC, 2011)
Start date: 2012-08-01
End date: 2013-07-31
Duration (months): 12.0
Total project cost (EUR): 149990.0
EU funding (EUR): 149990.0
Participants: 1
Project status: CLOSED

BioNLight has been designed to investigate the prospective of commercially exploiting our multimodal nanoparticle technology in the biological imaging market. The introduction of this technology will open up an entirely-new window of molecular imaging possibilities, thereby supporting advances in biology, drug discovery & development and diagnostics. Funded by ERC, Prof. Brunsveld and colleagues have developed modular nanoparticles that exactly address the needs of the molecular imaging field. These nanoparticles of organic nature can be produced in a reproducible one-step method by self-assembly in water. The result is a highly-robust and biocompatible nanoparticle that can be modulated to emit any desirable colour frequency with long-term emission and high photostability. Moreover, they can be functionalised with multiple ligands thanks to great control over surface functionality and can be prepared not only for fluorescent studies, but also for other imaging technologies. In practise this implies that the technology platform can be used to advance a wide range of in-vitro and in-vivo assays and to visualise yet-uncovered processes. It is the objective of BioNLight to select the most interesting applications for commercialisation and to build up a prospectus that can be used to convince future customers of the practicability and the imaging power of our technology platform. Besides, we aim to construct a sound business model and strategy for commercialisation. This will be done by external validation of the nanoparticles by industry followed by final optimisation, by means of an extensive market study, by building a strong IP position and by setting up a business plan with detailed financial feasibility projections. The ERC Proof of Concept Grant will enable us to take the ERC Starting Grant results to a sound business proposition.

Keywords: 204554
Uncovering metabolic cycles in mammals and dissecting their interplay with circadian clocks (METACYCLES)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Molecular and Structural Biology and Biochemistry
Countries involved: Israel
Call:  (ERC-2012-StG_20111109, 2012)
Start date: 2012-11-01
End date: 2017-10-31
Duration (months): 60.0
Total project cost (EUR): 1499980.0
EU funding (EUR): 1499980.0
Participants: 1
Project status: CLOSED

The physiology and behavior of mammals are subject to daily oscillations that are driven by an endogenous circadian clock. The mammalian circadian timing system is composed of a central pacemaker in the brain that is entrained by daily light-dark cycles and in turn synchronizes subsidiary oscillators in virtually all cells of the body. The core clock molecular circuitry is based on interlocked negative transcription-translation feedback loops that generate daily oscillations of gene expression in cultured cells and living animals. Circadian clocks play a major role in orchestrating daily metabolism and their disruption can lead to metabolic diseases such as diabetes and obesity. Concomitantly, circadian clocks are tightly coupled to cellular metabolism and respond to feeding cycles. The molecular mechanisms through which metabolism regulates clocks’ function are just starting to emerge. Recent work of ours and others revealed that NAD+/NADH are implicated in the function of circadian clocks, yet the molecular mechanisms involved are largely unknown. We propose to intensively study the role of NAD+/NADH in the function of circadian clocks and to reveal the underlying mechanisms. The functional interplay between circadian clocks and metabolism raises the question whether there are daily cycles in cellular metabolism and intracellular metabolites. Hitherto, direct measurements of daily changes in cellular metabolism and intracellular metabolite levels are still in their infancy. Our overarching goal is to identify metabolic cycles in mammals and mechanistically address their interplay with circadian clocks. We will monitor metabolic outputs in intact cells and living animals and systemically measure daily changes in intracellular metabolites. Our findings are expected to push forward a paradigm shift in the circadian field from the current “transcriptional-translational clocks” to “metabolic clocks”.

Keywords: circadian rhythms,clock,nad/nadh,metabolism