Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Polar Regions in the Earth System (PolarRES)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Fighting and adapting to climate change
Action type: Research and Innovation actions
Countries involved: Ukraine,Germany,Belgium,Finland,Finland,Sweden,China,Norway,Russian Federation,Belgium,Norway,Netherlands,United Kingdom,Denmark,United Kingdom
Call: Polar climate: understanding the polar processes in a global context in the Arctic and Antarctic Regions (H2020-LC-CLA-2020-2, 2020)
Start date: 2021-09-01
End date: 2025-08-31
Duration (months): 48.0
Total project cost (EUR): 8133841.25
EU funding (EUR): 7996321.25
Participants: 17
Project status: SIGNED

The overall objective of PolarRES is to provide new insights into key local-regional scale physical and chemical processes for atmosphere-ocean-ice interactions in the Arctic and Antarctic, their responses to, and influence on, projected changes in the global circulation and their implications for society and the environment. PolarRES will zoom into the climate of both Polar regions with state-of-the-art regional climate models (RCMs), run at unprecedented resolutions, to investigate the influence of projected changes in the global circulation on the climate of the Arctic and Antarctic. Polar climates in a global context remains poorly understood and thus climate change projections in Polar regions have large uncertainties and this hampers mitigation and adaptation efforts. PolarRES proposes an innovative ‘storyline’ approach and novel analysis methods to address these challenges. We will accomplish this by exploiting the recent CMIP6 global climate model (GCM) projections and novel developments in GCMs such as variable resolution grids. High-resolution regional projections will be co-designed with and exploited by impact modellers to produce impact-relevant projections of future climate change for both Polar regions. PolarRES will combine these high-resolution simulations from state-of-the-art RCMs and next generation fully coupled RCMs with a comprehensive range of existing and novel observations (e.g. YOPP and MOSAiC) including satellite products from relevant projects funded by the ESA Earth Observation Programme. The consortium consists of leading European groups in the areas of polar-lower latitude teleconnections, polar oceanography, meteorology, climatology, biogeochemistry, global climate modelling, and regional climate modelling in the Arctic and Antarctic. PolarRES will contribute to the EU Strategy on Climate Action and EU strategy for international cooperation in R&I.
The fate and therapeutic potential of human neoantigen-specific T cells (Tumour T cells)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-09-01
End date: 2024-03-08
Duration (months): 24.0
Total project cost (EUR): 174806.4
EU funding (EUR): 174806.4
Participants: 1
Project status: SIGNED

Cancer is a global health burden and the second leading cause of death worldwide. In recent years, the development of immunotherapy has revolutionised the approach to cancer therapy. A significant limitation, however, is that it is only effective in a subset of patients and the biggest challenges remain the identification of immunogenic targets on human cancers and overcoming immunosuppression. Neoantigens, which are newly formed antigens that arise from mutated tumour proteins, are promising targets in immunotherapy. With the proposed project, we aim to investigate the immune response against human neoantigens which will be induced in a novel humanised tumour mouse model. This unique mouse model harbours the entire human CD8 TCR repertoire and expresses human HLA-2. We will test whether human neoantigens can elicit spontaneous anti-tumour T cell responses in acute inflammatory versus resting conditions, ultimately leading to tumour rejection. We hypothesise that T cells are not able to reject tumours in absence of acute inflammation, similar to the development of most human cancers. To investigate why neoantigen-specific T cells become dysfunctional and fail to reject tumours, we will characterise the functional state and metabolic phenotype of neoantigen-specific T cells by flow cytometry, metabolomics and TCR sequencing. In addition, we will characterise the TCR repertoire of T cells that cause tumour rejection under acute inflammatory conditions. Lastly, we will compare the therapeutic efficacy of adoptively transferred T cells transduced with newly identified TCRs with neoantigen-based vaccines against large established tumours. Overall, this project will contribute to the understanding of immunosurveillance and establish novel techniques to test predicted neoantigens. The identification of human immunogenic targets has the potential to make a global impact on cancer intervention.

Keywords: neoantigens,cancer,immunology,t cells,immunometabolism,humanised mouse model,tumour microenvironment,cancer immunotherapy,adoptive cell transfer
The League of Nations and the development of international law: from promotion strategies to giving shape to international legal instruments (LONintLAW)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-08-01
End date: 2023-07-31
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: SIGNED

This postdoc project provides the first historical account of how the predecessor of today’s United Nations, the League of Nations, fundamentally contributed to the development of international law in the early Twentieth Century. With the help of an innovative methodology, the project will lay bare how: firstly, the League forged diplomatic strategies to convince member states to accept the regulation of their actions through the signature of over one hundred international treaties and conventions; secondly, it developed techniques to draft and implement multilateral legal instruments, which still prevail today. Thus, the project will make a pathbreaking contribution to both the history of international law and the history of international organizations, and it will be of interest for historians, legal scholars and political scientists. It will be carried out in an environment which currently represents Europe’s most thriving research hub in the history of international law. Moreover, it is specifically designed to provide the scientific and non-scientific training activities that I need at this stage to take my career to the next level.

Keywords: 20th century history,interwar period,history of the league of nations,history of international law,juridification of international relations in the 1920s and 1930s
Reinforcing research potential in the Laboratory for Chemical Contaminants at the Faculty of Technology towards the establishment of the Centar of Excellence in Food Safety and Emerging Risks (CEFSER)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Serbia
Call:  (FP7-REGPOT-2008-1, 2008)
Start date: 2009-02-01
End date: 2012-07-31
Duration (months): 42.0
Total project cost (EUR): 1007652.0
EU funding (EUR): 897650.0
Participants: 1
Project status: CLOSED

Strategic objectives of the project is to reinforce the research capacities of the Laboratory for Chemical Contaminants (LabCHEMCONT) at the Faculty of Technology/University of Novi Sad, in order to establish a Centre of Excellence in Food Safety and Emerging Risks (CEFSER), strengthening its leading role in the regional research community. Food safety is currently one of the most important global issues that cannot be dealt with by individual but rather joint efforts, which means that harmonized approach to all food safety issues across scientific community, including the issue of emerging pollutants, is necessary. LabCHEMCONT is an already internationally well-recognized research lab focused on detecting chemical contaminants in food. However, the existing equipment at LabCHEMCONT could not satisfy increasing stringent regulatory standards that require methods capable for highly sensitive and multi-residues sample analysis. In order to establish CEFSER, the first key issue is purchasing of two Ultra Performance Liquid Chromatographs with triple qudrupole and also with high resolution mass spectrometers, which are the latest breakthrough food safety system. Reinforcement of human potential will concomitantly accompany the equipment upgrade and it will be performed through trainings, exchange visits, workshops. Developing strategic partnerships by networking with the researchers in EU Member States that have long term experience in the food safety and emerging pollutants analysis will support the CEFSER establishment as a modern laboratory capable to contribute to ERA significantly. Knowledge gained within the project will be disseminate at national, regional and European level (workshops, conferences, web site, training materials, etc). Forming a database on main issues in food safety and emerging pollutants will be a part of the project in order to facilitate communication between Balkan region and the rest of the Europe, contributing to the dissemination of scientific information and results of the past and ongoing research.

Keywords: exchange know-how,trainings,dissemination,database
Labor Markets, Economic Fluctuations, and Monetary Policy (LABPOL)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Individuals, institutions and markets
Countries involved: Spain
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-01-01
End date: 2011-12-31
Duration (months): 36.0
Total project cost (EUR): 600000.0
EU funding (EUR): 600000.0
Participants: 1
Project status: CLOSED

The New Keynesian (NK) model has emerged in recent years as the workhorse for monetary policy analysis. The first part of the proposed project is motivated by two shortcomings of that framework: (i) the lack of an explicit analysis of unemployment and its potential role in the design of policy, (ii) the limited empirical support for the model s wage-setting block. One of the objectives of the proposed project is the assessment of the empirical relevance of the specification of the wage-setting bock found in standard versions of the NK model, with a special focus on their implied wage-unemployment dynamics. As part of my project, I will show how the standard NK model with staggered wage setting implies a relationship between wage inflation and unemployment that fails to capture important features of the data. I also plan to develop and study an extension of the NK model that incorporates in a tractable way real wage rigidities (coexisting with nominal rigidities), with the objective of (i) assessing their relative role in explaining the observed patterns of wages and unemployment, (ii) analyzing their implications for the design of monetary policy. The second part of the project is motivated by the significant changes in the co-movements among some key macro variables that have accompanied the recent period of low macroeconomic volatility (the so-called Great Moderation). One objective of the proposed research is to understand the role that structural change in the labor market may have played as a source of those changes. In particular, I plan to analyze the causes of the vanishing pro-cyclicality of labor productivity and their potential causes, including a more subdued use of labor hoarding by firms, possibly as a result of lower hiring/firing costs. In addition, I plan to study the consequences that such structural changes may have had on wage setting, and their ability to account for the apparent increase in wage flexibility during the recent period.

Keywords: new keynesian model,optimal monetary policy design,nominal rigidities,great moderation,labor market frictions,real wage rigidities.
CEI Research Fellowship Programme (CERES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy,Italy,France
Call:  (FP7-PEOPLE-2007-2-3-COFUND, 2007)
Start date: 2009-04-01
End date: 2014-03-31
Duration (months): 60.0
Total project cost (EUR): 1008000.0
EU funding (EUR): 403200.0
Participants: 4
Project status: CLOSED

The Central European Initiative intends to strengthen its CEI Research Fellowship Programme both in terms of quantity and quality, i.e. increasing the number of fellowship-years while improving the fellows’ employment conditions. The CEI Research Fellowship Programme was established in 2005 under the aegis of the CEI Science & Technology Network, promoted by the CEI along with six Trieste-based centres of excellence with the purpose of enhancing scientific cooperation across its region. This proposal aims at reinforcing the CEI Research Fellowship Programme: it will cover a period of 44 months and envisage 30 incoming fellowships (12 months each) to be awarded to experienced researchers from CEI countries. Annual calls will be advertised through the CEI networks of experts and communication tools, disseminated on the occasion of CEI sponsored events and during both institutional and technical meetings. Researchers will be selected by an ad hoc Committee, whose composition will follow the “European Charter for Researchers and Code of Conduct for their Recruitment”; fellows will be given the opportunity to carry out research in one of the 5 partner institutions (International Centre for Theoretical Physics - ICTP; International Centre for Genetic Engineering and Biotechnology - ICGEB; Cluster in Biomedicine - CBM; International School for Advanced Studies – SISSA; Synchrotron – ELETTRA), which altogether cover a large spectrum of highly relevant scientific research such as physics, maths, genetics, biotechnology, neuroscience, nano-science, bioinformatics. This will allow a considerable freedom of choice as to research topics, in line with the bottom-up approach pursued by all “Marie Curie Actions”. By exploiting synergies between the Community action and the regional impact of its Research Fellowship Programme, the CEI will be able to strengthen trans-national mobility of researchers and to offer them excellent conditions for the development of their careers.

Keywords: neurosciences,physics,mathematics,molecular biology,genetics,bioinformatics,biotechnology,nanotechnology
Fostering trans-national mobility in the Life Sciences - Co-funding of the EMBO Long-term Fellowship Programme (EMBOCOFUNDFP7)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2007-2-3-COFUND, 2007)
Start date: 2009-10-01
End date: 2012-09-30
Duration (months): 36.0
Total project cost (EUR): 4338400.0
EU funding (EUR): 4338400.0
Participants: 1
Project status: CLOSED

The EMBO Fellowship Programme supports international mobility and exchange in the molecular life sciences. Renowned for its attention to scientific excellence, the programme has funded thousands of talented young scientists since its establishment in the 1960s. EMBO Long-term Fellowships support advanced research and training, awarding funds to postdoctoral scientists for research visits between European countries or when justified worldwide. Since 2001, the demand for EMBO Fellowships more than doubled, illustrating the increasing high demand for trans-national mobility and postdoctoral training in the life sciences. This proposal will outline how co-funding of EMBO Long-term Fellowships will positively contribute to the further development of the ERA.

Keywords: natural sciences,molecular life sciences,fellowships,international mobility
Enhancing the Research Potential of the NCSR “Demokritos” Environmental Research Laboratory in the European, National and Regional Research Areas (PERL)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Greece
Call:  (FP7-REGPOT-2008-1, 2008)
Start date: 2009-01-01
End date: 2011-12-31
Duration (months): 36.0
Total project cost (EUR): 1135000.0
EU funding (EUR): 797000.0
Participants: 1
Project status: CLOSED

PERL addresses the FP7-REGPOT-1 call to improve the research potential of the Environmental Research Laboratory (EREL) of the National Centre for Scientific Research “Demokritos”, Region of Attica, Greece, in the fields of air pollution and hydrogen technologies. The Laboratory has achieved over the last years significant progress and growth but needs further support to undertake the required leap forward and evolve to a major R&D center. The present proposal consists of a set of coherent activities, which arise from the implementation of the EREL Action Plan, directly aiming at strengthening the research capacity of the Laboratory for successful participation in research activities at European, National and Regional level. The proposed action will be built on three solid pillars: • Research infrastructures, which includes the recruitment of expert scientific personnel, modernization of existing unique facilities and acquisition of new equipment • Strategic partnership and collaboration between EREL, renowned research entities and the industry, in key thematic priorities of the ERA and National Research Activities • Outreaching of the EREL scientific achievements and research capacities as a means of increasing visibility of the work and expanding R&D collaboration. The proposal embraces networking activities with regard to research, innovation and technology with other “excellent” research institutions in EU. Emphasis is placed on achieving strategic partnerships and establishing research staff mobility with entities from regions facing similar R&D challenges thus enhancing the European, National and regional impact of EREL activities. The successful outcome of PERL will contribute essentially towards integrating the R&D activities of EREL in the general framework of European scientific and technological cooperation in key thematic priorities. This would allow the EREL members to participate effectively in European S&T cooperation initiatives and networks.

Keywords: research potential,regional capacity,infrastructures,strategic partnership,outreaching,era,hydrogen energy,air quality
Unlocking the Croatian Textile Research Potentials (T-POT)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Croatia
Call:  (FP7-REGPOT-2008-1, 2008)
Start date: 2009-03-01
End date: 2012-02-29
Duration (months): 36.0
Total project cost (EUR): 1068585.05
EU funding (EUR): 959300.0
Participants: 1
Project status: CLOSED

T-Pot aims to reinforce research potentials of Faculty of Textile Technology (TTF) in order to strengthen university sector to become one of the components of national innovation. The goals are to develop the capacity for breakthrough research leading to innovative textile and textile related products contributing in this way to local industry. Top scientists will be attracted to the country for exchange of know-how and guidance of Croatian textile manufacturers. Prerequisite for these objectives is an active participation in research projects and successful competing for funds in the European Research Area. For that reason T-Pot will reinforce human and material potential, so as research infrastructure. Three strategic partnerships with well established research institutions will be developed and further communication with other textile centres with similar scientific interest will be facilitated. Employment of 3 new PhD students, their training at 3 prestigious research institutions, so as acquisition of selected equipment will be significant contributions to the project goals. Dissemination activities such as organization of workshops, trainings, forums, round table and 2 conferences will contribute to spreading excellence and exploiting of project results and knowledge in particular within the industry. All stated activities will sustain the progress of real integration and cohesion of Croatian textile/clothing (T/C) sector into European Union Framework Programmes.

Keywords: reinforcement of s&t,strategic partnerships,mobilisation of human & material resources,dissemination of scientific information and research results