Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Entropy for Quantum Information Science (QEntropy)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Germany,United Kingdom
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2022-11-01
End date: 2027-10-31
Duration (months): 60.0
Total project cost (EUR): 1499835.0
EU funding (EUR): 1499835.0
Participants: 2
Project status: SIGNED

Entropy for quantum systems is the fundamental, interdisciplinary concept to quantify the advantage of quantum technologies for processing of information. It is well-established that the quantum advantage originates from the strong correlations found in the entanglement spectrum of multipartite quantum states, as exactly characterised by the information-theoretic tool quantum entropy. Contrary to the case of classical systems, however, our knowledge about the mathematics of quantum entropy is much more limited. Nonetheless, special entropy inequalities that are known to hold in the quantum case, such as the strong sub-additivity of quantum entropy, give crucial insights into the entanglement structure of multipartite quantum states. In this project, I will focus on understanding multipartite entropic constraints, which will lead to tight characterisations of the ultimate, physical limits of quantum information processing. My recent mathematical works in quantum information led to operational extensions of the concept of strong sub-additivity from the seventies. Starting from that, I propose a research program that will lead to an understanding of quantum entropy that is on the same level as for the classical, commutative case. In the first part of my project, I will establish techniques in matrix analysis and optimisation theory to understand the interplay of arbitrarily many non-commuting operators. This mathematical framework will allow to prove novel quantum entropy inequalities that lead to refined approximations on the entanglement structure of multipartite quantum states. Second, I will employ the newly obtained entropic constraints to derive approximation algorithms for a plethora of fundamental problems in quantum information science. This includes schemes for achieving the physical limits of cryptography, resolving entropic additivity questions in information theory, and providing algorithms for the description of strongly interacting many body systems.

Keywords: entropy inequalities,multipartite entanglement,multivariate trace inequalities,approximation algorithms,quantum communication,quantum device independent cryptography,quantum many body systems
Christian-Muslim families dealing with religious pluralism in everyday family life Religious reconstruction in religiously mixed marriages (ReMix)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-02-12
End date: 2020-02-21
Duration (months): 24.0
Total project cost (EUR): 160800.0
EU funding (EUR): 160800.0
Participants: 1
Project status: CLOSED

Mixed families are both the index and agent of social change: they exemplify the increase in migration flows and provide us with an opportunity to analyse the everyday processes related to Europe’s growing pluralism. Quantitative studies demonstrate that interfaith marriages lead to higher divorce rates, suggesting that the latter are due to communication difficulties and disagreements caused by cultural differences between partners, as well as to hostility from families of origin, religious institutions and society at large. However, rather than being firmly and empirically established, these concepts remain mere assumptions and, as such, also conceal the ways in which those involved actively and reflexively deal with these dynamics to prevent damage to their relationship. Much scholarly attention has focused on couples defined as Islamic-Catholic or Muslim-Christian, which represent a paradigmatic case study of “mixedness” that typically incorporates differences pertaining to ethnicity, class and faith. The challenge of this project gives an empirically adequate exploration of a pattern firmly established in quantitative studies, i.e., that interfaith marriages give rise to high divorce rates. This project thus aims to understand, through an in-depth qualitative study, the daily life of such families: what differences are responsible for tension between spouses, how they deal with this in order to avoid damage to their relationship, and how gender interferes with these problems. Mixed marriages will be a key to examine the whole of society facing new family changes, Islam and religious diversity in everyday life. The research project addresses the EU lines of Horizon 2020, studying one of the major challenges for an “inclusive and multicultural” Europe. The fellowship will provide me with wider competence, publications and connections necessary to apply for an ERC Grant in 2019.

Keywords: mixed marriages,christian muslim families,islam,muslims in europe,sociology of culture and religion,cultural processes
The role of cultural heritage in socio-economic development and preservation of democratic values (HERItage)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Reflective societies - cultural heritage and European identity
Action type: Coordination and support actions
Countries involved: Croatia
Call: Presidency events- Croatia (H2020-IBA-SC6-Croatia-Presidency-2019, 2019)
Start date: 2019-11-21
End date: 2020-09-20
Duration (months): 10.0
Total project cost (EUR): 249500.0
EU funding (EUR): 249500.0
Participants: 1
Project status: CLOSED

The proposal’s main aim consists in organizing an international conference entitled “The role of cultural heritage in socio-economic development and preservation of democratic values – HERItage". The conference was originally planned to be organised in Opatija by the University of Rijeka, as part of the Croatian Presidency of the Council of the European Union in March 2020, but due to the outbreak of the COVID-19 pandemic the conference is organised as a virtual one from June 15 to June 18, 2020. The original three-day conference with more than 300 speakers has been turned into four video sessions. The main objective of the conference is to identify priorities for an agenda to safeguard and develop cultural heritage as one of Europe’s most defining features – a sense of belonging and of our economic driver. The HERItage conference is intrinsically related to the European Capital of Culture 2020 (ECOC2020), which takes place in Rijeka in 2020. The conference hence aims to maintain and develop the quality and continuity of scholarly debates and to encourage international and cross-border cooperation. Particularly the conference aims to discuss: - The role of universities in promoting and preserving cultural heritage: education, research and social responsibility - The role of scientific research in strengthening the preservation of industrial heritage - Challenges and opportunities of digital transformations: the role of digital tools in preserving cultural and industrial heritage Focus will also include public policies: cultural heritage and democratic values and cooperation and innovation: cultural heritage and social transformation. The conference builds on the provisions of the Horizon 2020 Work Programme 2018-2020, SC 6 as well as on the “Orientations towards the first Strategic Plan implementing the research and innovation framework programme Horizon Europe”. It also relies on the synergistic and collaborative efforts of the Joint Programming Initiative Cultural Heritage and Global Change and its perspective ties to digitisation and computing facilities. The HERItage conference will gather stakeholders from academia, governmental organizations, industries, SMEs and end users of research results.

Keywords: cultural heritage,croatia,rijeka,digital tools,industrial heritage
New Diagnostics for Infectious Diseases: “ND4ID” (ND4ID)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Israel,Spain,Germany,Switzerland,Switzerland,Belgium,Belgium,Sweden,Belgium,Belgium,France,Netherlands,Denmark,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2015, 2015)
Start date: 2016-03-01
End date: 2020-02-29
Duration (months): 48.0
Total project cost (EUR): 3860507.52
EU funding (EUR): 3860507.52
Participants: 23
Project status: CLOSED

Infectious diseases are a major burden to public health and the global economy, not in the least due to antimicrobial resistance. Rapid point of care (POC) in vitro diagnostics (IVD) are key tools in the effective clinical management of patients with infectious diseases. Yet there is still a large unmet clinical need for more rapid POC IVDs generating more clinically relevant, actionable information. Effectively addressing this need requires a change in the current approach in training researchers on IVDs, generating a new ‘breed’ of IVD researchers capable of closing the gap between the clinical and technological perspective. ND4ID takes up this challenge by offering 15 ESRs a world-class first of its kind training programme where they will be exposed to the full breadth of disciplines spanning clinical, technological and market-oriented viewpoints, from both the academic and non-academic sector. Through a set of synergistic research projects on novel POC assays, targeting the most important and urgent clinical needs at world leading academic or private sector research groups, the ESRs are offered a holistic training program, preparing them to be lead players in the future IVD field. This training through research is augmented by a unique comprehensive network-wide training programme covering clinical, technical and translational knowledge and skills of relevance to IVD research, development and exploitation. As such, ND4ID will deliver ESRs that will be in high demand serving as an example for other academic and non-academic actors active in training IVD researchers and further strengthening Europe’s position in the internally competitive arena of IVD technology.

Keywords: infectious diseases,antimicrobial resistance,in vitro diagnostics
Dynamics of dense nanosuspensions: a pathway to novel functional materials (nanoPaInt)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Spain,Israel,Germany,Germany,Italy,Germany,Belgium,Bulgaria,Poland,Netherlands,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 3818430.72
EU funding (EUR): 3818430.72
Participants: 13
Project status: SIGNED

Nanoparticles serve as additives for controlling the liquid properties. They are extensively applied in food industry and home care products, they are the essential part of ink and paint formulations and of coatings, they are used for manufacturing of functional materials and are very promising drug carriers. The presence of nanoparticles in air or in water can influence the Earth ecology and human health. Although dilute suspensions of nanoparticles which are close to equilibrium have been extensively studied, in many important applications, such as food industry and printing, the suspensions are dense, or strongly interacting, they experience significant external stress and are far from equilibrium. A fundamental understanding of interaction between nanoparticles in liquid bulk and at interfaces, allowing to effectively use particulate systems in these applications, has not yet been achieved. The aim of the NanoPaInt network is understanding, predictive modelling and application of the strongly interacting nanoparticle-laden systems out of equilibrium. The specific objectives are: understanding strong interactions between the nanoparticles and their effect on the rheological properties of suspensions; understanding the behavior of nanoparticles in complex interfacial flows under strong external forces and with wetting and dewetting; design and applications of smart capillary nanosuspensions; drying of nanosuspensions towards assembly and fabrication of functional superparticulate systems. The training aim of NanoPaInt network is to support the career development of young researchers both in academic and non-academic sectors and to train a new generation of creative, mobile, entrepreneurial and innovative early-stage researchers (ESRs) through the experience of independent and interdisciplinary research, participation at local and network-wide training activities and intersectorial and international secondments.

Keywords: nanoparticles,rheology,3d printing,capillary suspension
Astrophysics with Stored Highy Charged Radionuclides (ASTRUm)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-04-01
End date: 2021-09-30
Duration (months): 66.0
Total project cost (EUR): 1874750.0
EU funding (EUR): 1874750.0
Participants: 1
Project status: CLOSED

The main goal of ASTRUm is to employ stored and cooled radioactive ions for forefront nuclear astrophysics research. Four key experiments are proposed to be conducted at GSI in Darmstadt, which holds the only facility to date capable of storing highly charged radionuclides in the required element and energy range. The proposed experiments can hardly be conducted by any other technique or method. The weak decay matrix element for the transition between the 2.3 keV state in 205Pb and the ground state of 205Tl will be measured via the bound state beta decay measurement of fully ionized 205Tl81+. This will provide the required data to determine the solar pp-neutrino flux integrated over the last 5 million years and will allow us to unveil the astrophysical conditions prior to the formation of the solar system. The measurements of the alpha-decay width of the 4.033 MeV excited state in 19Ne will allow us to constrain the conditions for the ignition of the rp-process in X-ray bursters. ASTRUm will open a new field by enabling for the first time measurements of proton- and alpha-capture reaction cross-sections on radioactive nuclei of interest for the p-process of nucleosynthesis. Last but not least, broad band mass and half-life measurements in a ring is the only technique to precisely determine these key nuclear properties for nuclei with half-lives as short as a millisecond and production rates of below one ion per day. To accomplish these measurements with highest efficiency, sensitivity and precision, improved detector systems will be developed within ASTRUm. Possible applications of these systems go beyond ASTRUm objectives and will be used in particular in accelerator physics. The instrumentation and experience gained within ASTRUm will be indispensable for planning the future, next generation storage ring projects, which are launched or proposed at several radioactive ion beam facilities.

Keywords: heavy ion storage rings,highly charged radioactive ions
Biochemically modified messenger RNA encoding nucleases for in vivo gene correction of severe inherited lung diseases (BREATHE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Germany
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-04-01
End date: 2020-03-31
Duration (months): 60.0
Total project cost (EUR): 1497125.0
EU funding (EUR): 1497125.0
Participants: 1
Project status: CLOSED

Surfactant Protein B (SP-B) deficiency and Cystic Fibrosis (CF) are severe, fatal inherited diseases affecting the lungs of ten thousands of people, for which there is currently no available cure. Although gene therapy is a promising therapeutic approach, various technical problems, including numerous physical and immune-mediated barriers, have prevented successful application to date. My recent studies were the first to demonstrate the life-saving efficacy of repeated pulmonary delivery of chemically modified messenger RNA (mRNA) in a mouse model of congenital SP-B deficiency. By incorporating balanced amounts of modified nucleotides to mimic endogenous transcripts, I developed a safe and therapeutically efficient vehicle for lung transfection that eliminates the risk of genomic integration commonly associated with DNA-based vectors. I also assessed the delivery of mRNA-encoded site-specific nucleases to the lung to facilitate targeted gene correction of the underlying disease-causing mutations. In comprehensive studies, we show that a single application of nucleases encoded by nucleotide-modified RNA (nec-mRNA) can generate in vivo correction of terminally differentiated alveolar type II cells, which more than quadrupled the life span of SP-B deficient mice. Together with my working group, I aim to further develop this technology to enhance the efficiency and safety of nec-mRNA-mediated in vivo lung stem cell targeting, providing an ultimate cure by permanent correction. Specifically, we will test this approach in humanized mouse models of SP-B deficiency and CF. Developing and genetically engineering humanized models in vivo will be a critical step towards the safe translation of mRNA based nuclease technology to the clinic. With my competitive edge in lung-transfection technology and strong data, I feel that my group is uniquely suited to achieve these goals and to make a highly valuable contribution to the development of an efficient treatment.

Keywords: modified messenger rna,in vivo gene correction
Reading Descartes: A Reassessment of the Shaping and Transmission of Knowledge in the Seventeenth Century (READESCARTES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-03-01
End date: 2023-02-28
Duration (months): 24.0
Total project cost (EUR): 183473.28
EU funding (EUR): 183473.28
Participants: 1
Project status: CLOSED

The objective of this project is to provide the first in-depth study of the handwritten commentaries on the treatises of René Descartes. This study is important because such sources were crucial in shaping the intellectual revolution occurring in Europe during the 17th century, in which Descartes played a foremost role. However, we still do not have a complete grasp of why his ideas were so important to this revolution, because we do not know how his texts were closely read. The key to understand this process of reading and knowledge-building is the analysis of this kind of sources, up to now neglected by historians. Andrea Strazzoni has preliminarily ascertained their crucial role for the reception of Cartesianism while working on two monographs in the history of philosophy and science, making him the ideal researcher for this project. He has assessed the existence of 109 not retrieved items, plus 38 already retrieved ones. These commentaries constitute a body of literature whose complete analysis will be made possible by this project, focused on those authored by the first teachers of Cartesian ideas: Johannes de Raey and Johannes Clauberg. This study is now timely, because it benefits from new directions of investigation: (a) the study of reading and note-taking practices, (b) a transnational approach to the history of thought, (c) the application of digital mapping tools to large amounts of texts. Such approaches are now at the centre of new researches, led at Venice Ca’ Foscari by the applicant’s supervisor, Marco Sgarbi, and by Dirk van Miert at Utrecht, destination of a secondment. The project integrates these approaches in order to pursue its objective along three lines of investigation: (1) the search for uncatalogued handwritten sources, (2) their textual reconstruction and mapping, (3) the analysis of their use and dissemination. This project will enable Strazzoni to become a leading scholar in early modern philosophy, and to apply for a tenured position.

Keywords: history of early modern philosophy,ren descartes,manuscripts,reading,note taking