Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Transgender and Intersex protection from gender-based violence: exploring new directions (TRANS-END)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Argentina,Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-01
End date: 2021-04-30
Duration (months): 36.0
Total project cost (EUR): 215285.4
EU funding (EUR): 215285.4
Participants: 2
Project status: CLOSED

This project addresses a pressing issue: violence against individuals who challenge traditional gender norms and expectations. Recently, violence against transgender individuals -whose gender identity differs from their assigned gender at birth– and intersex individuals – whose bodies differ from the average male or female standards- has gained special attention. Such violence is labeled as 'hate crimes', 'transphobia' or 'anti-transgender violence,' rarely addressing its gender-based nature. This may prevent T/I from accessing the protection offered by the gender-based violence (GBV) framework, which is perhaps the most sophisticated system of protection within international human rights law (IHRL) today. Tensions among disciplines and interest groups may account for this. Recently, Sexual Orientation and Gender Identity (SOGI) rights has become the preferred concept to include T/I under the protection of IHRL. In addition, expanding the scope of the concept of gender in GBV beyond women seems resisted. In fact, human rights documents on GBV tend to focus on cis women -born as women and comfortable with such classification- and exclude T/I from such protection unless they "fit" such category, forcing their self-identification as male or female. The ‘visibility’ of violence against T/I questions legal conceptualizations of 'men' or 'women', offering a perfect opportunity to explore the potentially exclusionary effects of the m/f binary that exists in IHRL. Revisiting the conceptualizations of gender with this in mind could transform the scope of protection of the current GBV framework by including T/I and also improve the protection of women. This research takes a comprehensive approach to GBV and SOGI issues, exploring the formal and practical potential of the GBV framework to protect T/I individuals from violence. It entails a socio-legal analysis and incorporates a case study on Argentina, which promotes T/I rights but shows high levels of violence against TG/I.

Keywords: human rights,gender based violence,gender,cisgender,transgender,intersectionality,male,female binary
Scaling biological e-methanation as a Green Deal building block (Echaea)

Framework: Horizon 2020 — Societal Challenges
Action type: SME instrument
Countries involved: Germany,Denmark
Call: H2020-EIC Accelerator pilot –SME Instrument - Green Deal (H2020-EIC-SMEInst-2018-2020-4, 2020)
Start date: 2020-11-01
End date: 2023-09-30
Duration (months): 35.0
Total project cost (EUR): 3550000.0
EU funding (EUR): 2485000.0
Participants: 2
Project status: SIGNED

The decarbonisation of natural gas – the biggest energy import product into the EU today – through the production of renewable methane from bio-e-methanation (“e-methane”), a natural gas equivalent, is one of the cornerstones of the European energy transition. Our highly productive microorganism strain and pressure bioreactor design carry the potential to solve the challenge of providing cost-effective large-scale energy storage and a multi-purpose e-fuel. Echaea are the only company worldwide to have validated a biological methanation technology in industrial prototypes that turn CO2 into e-methane, using curtailed renewable power, and storing it in existing gas grids. The fully biogenic e-fuel can be used across sectors, for transportation, power generation or industrial heating. Our technology has shown to produce grid-quality e-methane in a continuous process at a 1MW scale (Biofos, DK Solothurn, CH) and now needs to be scaled up to commercial size. The EIC grant funded project will de-risk Echaea’s Power-to-Methane solution to market-readiness. Subsequently we will build a full 10MWe commercial demonstration plant at Roslev, Denmark, funded by the EIC equity facility. Once industrial operations have been demonstrated, the technology is ready for international roll-out. Expressions of interest for 12 10MWe plants have already been received. We have assessed a market potential today of around 500 biological methanation plants and of 5,000 in the EU, more around the world, by 2050. Green Deal impact: One 10MW plant will convert 5,700 mt of CO2 a year and produce 2,8m Nm3 e-methane, sufficient to heat 2,400 homes. By 2050, this technology could convert 0.8% of annual CO2 released in the EU. Echaea is a venture-backed company and co-led by a female executive, Doris Hafenbradl. A multi-disciplinary team of 33 employees is pursuing the mission of becoming the global leader for renewable methane production at scale.

Keywords: methane,renewable power,carbon,biogas,hydrogen,e methane,methanation,achaea
Sleep and episodic memory consolidation: ‘No-report’ paradigms, brain mechanisms, and dementia (SleepEpisMemory)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Israel
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-10-01
End date: 2025-09-30
Duration (months): 60.0
Total project cost (EUR): 2745000.0
EU funding (EUR): 2566250.0
Participants: 2
Project status: SIGNED

Episodic memory is a core element of the human mind, but how experiencing an episode consolidates into long-term memory remains a central unsolved question in cognitive science. We will test the hypothesis that hippocampal-cortical dialogue (HCD) during sleep promotes memory consolidation, a hypothesis that has been largely beyond direct testing in humans to date. Moreover, transcending report is essential, since it remains unclear if sleep improves memory per-se, or the ability to access and report memories. Conventional paradigms do not facilitate sleep and memory research in dementia, where it is vital. Based on my expertise, ongoing studies, and preliminary results, I propose a unique approach to address these gaps by combining novel approaches to recording and stimulating brain activity in human sleep with novel ‘no-report’ memory paradigms. We will go beyond the state-of-the-art in three synergistic domains: (1) Develop an ecological ‘no-report’ paradigm to study episodic memory, and its consolidation during sleep. (2) Test the role of sleep HCD in mediating human memory consolidation. (3) In dementia and aging, we will investigate to what extent disrupted HCD during sleep impairs memory consolidation, and whether noninvasive neuromodulation can improve memory in dementia. The proposed research has the potential to elucidate fundamental principles and transform conceptual insights of how sleep promotes episodic memory consolidation.
Assessing the feasibility of MT-011, a first-in-class drug to treat glaucoma and other neurodegenerative diseases via a breakthrough mechanism-of-action (SA-VOIR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Glaucoma is the world's leading cause of irreverisble blindness, affecting 20 million people in Europe and the US. Known as the Alzheimer’s of the eye, glaucoma is a neurodegenerative disorder that causes deterioration in peripheral vision. Affected patients report ‘seeing through a black tunnel’. Treatments to halt vision loss are available however, they are only applicable for the ‘high tension glaucoma’ subtype. For those diagnosed with ‘normal tension', which comprises over 30% of glaucoma patients, no treatments are available, and vision loss is imminent. New drugs that inhibit VASH, a newly elucidated enzyme that is hyperactivated in many neurogenerative diseases, have potential to address this need. We at MT-act are a biotechnological start-up who have identified a family of VASH-inhibiting small molecule drugs. Using an in-house proprietary biochemical assay followed by lead optimization, we have identified MT-011, which inhibits VASH with nanomolar affinity, as our lead candidate. Aside from glaucoma, VASH dysregulation is also implicated in other prominent neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Our assets therefore have an inherently broad applicability. We aim to develop MT-011 up to the stage of Phase 1 clinical trials, upon which we aim to commercialize the drug via a licensing deal with a pharmaceutical partner. We will then receive upfront and milestone payments with a estimated total deal size of €40M. We are currently in discussion with world-leading pharmaceutical companies Pfizer and Santen Pharmaceuticals, who have already indicated interest in our drugs. In SA-VOIR, we aim to strengthen the business case for MT-011 and to outline a detailed technical plan for its continued development. These documents will not only guide us in developing MT-011 towards Phase 1 trials in an effective and de-risked manner, it will also form critical components of a business plan that we will use to attract further investment.

Keywords: glaucoma,microtubulin,alzheimer s,neuroprotectant,neurodegenerative
Development of Fast Timing tools for Event Reconstruction at the high luminosity frontier (FasTER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Italy
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-05-01
End date: 2018-04-30
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

High luminosities at future particles colliders, such as the High Luminosity Large Hadron Collider (HL-LHC), will come at the price of a dramatic increase in the number of concurrent interactions of beam particles (referred to as pileup) per crossing in the experiments, implying serious challenges to the reconstruction of events. Due to the spread of the proton bunches along the beamline, collisions vertices at the HL-LHC are spread out over about 5 cm along the beam direction and about 160 ps in time. At the vertex densities foreseen at the HL-LHC, some vertices and the associated particles are so close to be merged by the track reconstruction forming fake jets of high transverse momentum. Moreover, the random overlap of energy deposits from neutral particles (mainly photons), that cannot be tied via a track to any vertex, will deteriorate the calorimeter performance in terms of energy measurement and particle identification, as particles appear to be less isolated. A promising tool advocated to mitigate the effects of pileup consists in complementing the high transverse (spatial) granularity of the detectors with extreme time resolution (of the order of 10 ps), that would allow energy deposits coming from different interaction vertices to be resolved in time. The goal of this project is the definition of a viable way to exploit precision timing in event reconstruction at HL-LHC and integrate and/or complement the calorimeter system of the Compact Muon Solenoid (CMS) with ultimate timing capabilities. The project will address both software aspects, with the development of innovative and dedicated algorithms for event reconstruction in 5 dimensions (space-time and energy), and hardware aspects, with the study of microchannel plates as candidate sensitive detector for a dedicated fast timing layer, eventually embedded in a preshower, to assist the calorimeters in single particle and photon timing.

Keywords: fast timing detector,micro channel plates,hl lhc
Binaural Tools for the Creative Industries (BINCI)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Germany,Germany,Spain,France,France,United Kingdom
Call: Support technology transfer to the creative industries (H2020-ICT-2016-1, 2016)
Start date: 2017-01-01
End date: 2018-06-30
Duration (months): 18.0
Total project cost (EUR): 1251112.5
EU funding (EUR): 993603.5
Participants: 7
Project status: CLOSED

BINCI’s main objective is to develop an integrated software and hardware solution to ease the production, post-production and distribution of 3D audio content meant to be experienced by consumers through headphones. BINCI tools for binaural 3D audio production will be fully suitable to develop professional applications in the creative industries (e.g. music, video games, virtual and augmented reality, etc). BINCI will deliver market ready solutions proven in real production environments. This goal will be attained by filling the gap between the common practices and tools used by the actors of the audio and music production industry and the playback tools/devices widely used by the end listeners. BINCI will set up an adhoc User Group in the centre of its innovations. This User Group consists of renowned European audio production companies and recording labels, musicians and professional audiovisual content creators. The User Group will be involved in the requirement gathering and in the testing of the BINCI solutions. They will also pioneer binaural 3D audio production. To stimulate the binaural 3D audio content demand at consumer level, BINCI will create audioguide experimental productions for three emblematic cultural and touristic sites: Sagrada Familia (Spain), Opera Garnier (France) and and Bayerische Staatsgemäldesammlungen – Pinakotheken (Germany). Altogether, these productions will be showcased to more than 500 real site visitors BINCI integrated approach to exploitation, dissemination and communication tasks will secure an increase of 25% to 40% in yearly revenues to BINCI participating companies¸ as a result of BINCI-derived products and services. For the creative industries, BINCI will generate yearly 10 to 20 million Euro worth in direct and indirect business in binaural 3D contents contracts for audioguides productions in international cultural and touristic sites. BINCI will permit European SMEs in the audio and music production to respond to that market demand.

Keywords: binaural audio,3d sound,headphones,audio producers,3d music,hrtf measurements,immersive experience
Implement a European-wide coordination of research and innovation programs on raw materials to strengthen the industry competitiveness and the shift to a circular economy (ERA-MIN 2)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Ensuring the sustainable supply of non-energy and non-agricultural raw materials
Action type: ERA-NET Cofund
Partnership: ERA-MIN 2 (ERA-NET)
Countries involved: Spain,Spain,Ireland,Italy,Argentina,South Africa,Germany,Belgium,Finland,Poland,Slovenia,Sweden,Türkiye,Romania,France,France,Brazil,Chile,Portugal
Call: ERA-NET Cofund on Raw materials (H2020-SC5-2016-OneStageB, 2016)
Start date: 2016-12-01
End date: 2022-11-30
Duration (months): 72.0
Total project cost (EUR): 16058787.31
EU funding (EUR): 4999890.01
Participants: 26
Project status: SIGNED

Building on the experience of ERA-MIN FP7 funded project, the objective of the ERA-NET Cofund on Raw Materials (ERA-MIN 2) is to strengthen the coordination of national and regional research programmes in the field of non-energy non-agricultural raw materials by implementing one joint call for proposals resulting in grants to third parties with EU co-funding. In line with the integrated strategy proposed in the EU Raw Materials Initiative and the Strategic Implementation Plan of the European Innovation Partnership on Raw Materials, the ERA-MIN 2 Call topics will address the three segments of the non‐energy non-agricultural raw materials: metallic, industrial and construction minerals and will cover the whole value chain: exploration, extraction, processing/refining, as well as recycling and substitution of critical raw materials. ERA-MIN 2 supports the objectives of the EIP on Raw Materials, particularly in the area of research and innovation co-ordination; improve synergy, co-ordination and coherence between regional, national and EU funding in the relevant research fields through international collaboration; reduce fragmentation of raw materials research and innovation efforts across Europe; improve use of human and financial resources in the area of raw materials research and innovation. As measures to maximise impact, ERA-MIN 2 will cooperate with the existing initiatives, projects and associations, by establishing an effective communication aiming to assure that all dissemination activities, including the promotion and follow up of project results, will reach out to a wider audience of stakeholders, therefore strengthening the raw material community. To further increase its impact and to better fulfil the overarching objectives, ERA-MIN-2 will develop and implement at least two additional joint calls without EU co-funding, in topics of common interest and based on the updated Roadmap provided by CSA VERAM.

Keywords: raw materials,metallic,industrial and construction minerals,recycling,substitution of critical raw materials,circular economy,coordination of funding programmes,international cooperation
BITNET INNOSUP (BITNET INNOSUP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Bosnia and Herzegovina
Call: H2020 ENTREPRISE EUROPE NETWORK SGA4 2020-2021 (H2020-EEN-SGA4-2020-2021, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 27478.75
EU funding (EUR): 27478.0
Participants: 7
Project status: CLOSED

BITNET Consortium (Business, Innovation and Technology Network-BITNET) as a single network of excellence, will build on the results of the BITIN and BITNET Network, offering integrated services in support to business, digitalisation and innovation. The BITNET partners agreed to work together within the Enterprise Europe Network, covering whole territory of Federation of Bosnia and Herzegovina (hereinafter FB&H). BITNET consortium will provide a variety of the Network services and continue to provide support to their clients in internationalisation, digitalisation, innovation and Single Market. BITNET Consortium will implement fundamental principles of the Network (client-centric approach, network effect and quality management) and combine a continued “no-wrong door” concept with the Network principles. The network of competent and proficient partners will implement the project. Consortium partners are: The Foreign Trade Chamber of Bosnia and Herzegovina (FTC), Sarajevo Economic Region Development Agency (SERDA), University of Sarajevo (UNSA), INTERA Technology Park (INTERA), Zenica Economic Development Agency (ZEDA), BIT Centre (BIT) and Development Agency of the Una-Sana Canton (DAUSC). The Consortium partners UNSA, INTERA and BIT will be acting as a special Consortium within the Project (BITNET INNOSUPP) that will be delivering Key Account Management (KAM) services and services to enhance the innovation management capacity of SMEs. All these activities will support SMEs on their way of becoming more competitive internationally.

Keywords: technology development,innovation management,internationalization,coaching for smes,client centric approach,services to enhance the innovation management capacity of smes
Genetic basis of emergent social behaviour from genotype-phenotype mapping (SocBehGenoPheno)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-07-01
End date: 2021-06-30
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

Social behaviour plays an important role in the survival and development of many species with the most conspicuous and ubiquitous form being collective behaviour – the coordinated action of two or more individuals of the same species. Despite immense interest in collective behaviour in biology, the dynamic relationship between genotypes and phenotypes characterising this phenomenon remains opaque. Understanding this link, however, is crucial to elucidating the mechanisms of collective behaviour and emergence of social structures, and, most importantly, the genetic origins of social behaviour. In this project, I aim to quantify the genotype-phenotype mapping in the social behaviour of the nematode worm Caenorhabditis elegans using quantitative phenotyping and computational modelling. Due to its unique amenability to exhaustive genetic analyses, trackability and rich collective properties (so-called collective feeding), C. elegans is a perfect system to address this question. My project will use high-throughput imaging data of social feeding in hundreds of different C. elegans strains. I will develop a novel dynamic multi-state model based on worm postures and spatial positions, allowing to quantitatively describe nematode social behaviour in a worm density-dependent manner. My research programme will, for the first time, rigorously examine the phenotypic behavioural space in C. elegans and test its tolerance to mutations in a social context, hereby providing insights into the genetic basis of emergent social behaviour. Such a study is extremely timely as it will build on the brand-new nematode data collected at my host university using cutting-edge imaging and tracking techniques. This interdisciplinary project will provide significant amounts of training in modern quantitative and systems biology, including data analysis and modelling, as well as in research project management and networking, and thus be an ideal stepping stone to an independent scientific career.

Keywords: social behaviour,collective behaviour,computational modelling,genotype phenotype mapping,c elegans,quantitative biology