Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Filter-less air pollution abatement system able to clean a wide range of pollutants at ground level for a healthier workplace and more sustainable environment. (APA)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Italy,Italy,Italy
Call: Boosting the potential of small businesses for eco-innovation and a sustainable supply of raw materials (H2020-SMEINST-1-2014, 2014)
Start date: 2015-05-01
End date: 2015-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 3
Project status: CLOSED

APA is a filter-less air pollution abatement system working with a wide array of emission produced during industrial processes. Through its efficient method of cleaning and purifying air, APA directly lowers emissions after industrial processes thereby reducing adverse health issues for employees and the overall pollutants produced contributing to climate change. APA cleans air with a radius of 25m and is a scalable system that can be customised for its application, either working alone or in a network. Pollutants that APA removes from the air include: particulate matter; heavy metals; hydrocarbons; pollen; spores; NOx; Sox; CO₂. The system utilises Is Tech’s patented state-of-the-art water-based, chemical-free, centrifugal force process instead of disposable filters, producing a water-based waste. In comparison to other systems, APA is innovative as its filter-less technology greatly reduces manufacturing and maintenance costs. Along with this, APA is unique in that it can be positioned in working environments rather than on the discharge points of industrial processing machines, this means workers benefit from a more direct impact of the air purification gaining a healthier working environment. The technology has reached a TRL of 7 and has been tested in various operational environments demonstrating proof of concept and significant air pollution reductions (until 99.99% on PM 10). The Phase 1 project aims at establishing a robust industrialisation and operational plan, at identifying all stakeholders in the value chain and securing appropriate suppliers, sale channels and strategic partnerships, at contacting potential early adopters that can ensure a quick market test and at strengthening the business model with an in-depth market analysis, sound marketing strategy and reliable financial projections. APA project is proposed by 2 Italian SMEs, Is TECH and Witech, who have strictly cooperated on the design, prototype development and test since the beginning.

Keywords: air purification,industrial emissions reduction,green economy,employee,health benefits,innovative technology
Life in Arsenic rich environments: a challenge or an opportunity? (AsLife)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-05-01
End date: 2018-04-30
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

Arsenic is a notorious toxin, and as such may have exerted a strong selective pressure on the distribution and evolution of life on Earth. Despite evidence supporting the high levels and prominent role of As on the primitive Earth, the essentiality and toxicity of As, and its impact on evolutionary processes remains unexplored. AsLife aims at taking a novel approach to assessing microbial As cycling by exploiting two linked «environments». The first are the microbial mats from High-Altitude Andean Lakes, where it is known that As concentrations are far above background levels. Specifically, living and diagenetically-modified microbial mats will be investigated using scanning hard X-ray nanoprobes emerging at synchrotron facilities. This non-invasive and non-destructive technique provides data on a sub-micrometer scale by which to tie physiological inference from trace metal(loid)s distribution and speciation patterns directly to the microfossil biomass. Thus, providing a means to understand the interplay between microbial metabolisms and bio-availability of trace metal(loid)s in living and fossil ecosystems. The second environment comprises laboratory cultures, using the sampling power of «adaptive laboratory evolution» to explore how microbes adapt and enhance As detoxification facing the extreme As levels present in Andean Lakes. These results will be discussed in light of genomic studies of As-rich microbiota performed by Argentinian colleagues. During this project I will contact colleagues of the Jet Propulsion Laboratory in charge of the 2020 Mars Science Rover Mission and linked objective of returning samples for future analysis on Earth. I believe that my expertise in imaging and analyzing bio-geochemical proxies at multiple scales on a encapsulated geological sample can be relevant for contributing to the «Seek Signs of Life» Exploration Strategy of the 2020 Mission, thus establishing a strong and effective collaboration between EU and USA.

Keywords: arsenic,primordial life,early earth,stromatolites,biogeochemical cycles,calcium carbonate,biosignature and synchrotron based x ray imaging
Aptamer nanostructures dual-targeted to the HER receptor family for cancer therapy (ADHERE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

The proposed research programme deals with the development of aptamer nanostructures for targeted cancer therapy. Immunotherapy encompasses a growing field of anti-cancer therapeutics that target cancer cells expressing specific antigens, such as members of the HER receptor. Currently, immunoglobulins directed to HER1, better known as EGFR, and HER2 are used in the clinical management of several types of cancer. There are, however, several disadvantages associated with the production and application of immunoglobulins. Moreover, there is evidence that dual-targeting of multiple receptors at the same time is advantageous for improving clinical outcome and reducing drug resistance. Aptamers, which are short single-stranded oligonucleotides that can bind a target molecule in a similar fashion as immunoglobulins, may form, due to their physicochemical properties, a superior alternative strategy for targeted cancer therapy. In ADHERE, I will design (WP1) and investigate in vitro (WP2) and in vivo (WP3) the use of aptamer nanostructures with bispecific (against both EGFR and HER2) and multivalent (up to 4 binding ligands) targeting properties for cancer cell targeting. The 24-month research project will be executed at the department of Polymer Chemistry and Bioengineering at the Zernike Institute for Advanced Materials, University of Groningen, The Netherlands. The aim of this MSCA IF fellowship is to integrate my extensive background in targeted drug delivery and cellular therapeutics within the host institute, which is highly experienced with DNA nanomaterials and is positioned among the top 10 institutes of the world in the field of material science. Importantly, this fellowship will strengthen my career perspectives, by allowing me to gain valuable new transferable skills and receive additional high-level training. This will enable me to position myself as a leading young scientist in the field of clinical nanomaterials.

Keywords: nanomedicine,drug targeting,targeted therapeutics,cancer therapy,aptamer,dna nanotechnology,her2,egfr
ERA-NET Cofund Promoting Gender Equality in H2020 and the ERA (GENDER NET Plus)

Framework: Horizon 2020 — Science with and for Society
Programme: Promote gender equality in particular by supporting structural change in the organisation of research institutions and in the content and design of research activities
Action type: ERA-NET Cofund
Partnership: GENDER NET Plus (ERA-NET)
Countries involved: Spain,Estonia,Austria,Spain,Ireland,Italy,Israel,Cyprus,Norway,Sweden,Belgium,France,Czechia,Canada
Call: ERA-NET Cofund – Promoting Gender equality in H2020 and the ERA (H2020-SwafS-2016-1, 2016)
Start date: 2017-09-15
End date: 2023-09-14
Duration (months): 72.0
Total project cost (EUR): 13554127.0
EU funding (EUR): 3768310.24
Participants: 18
Project status: SIGNED

Despite efforts to reduce fragmentation across the European Research Area, the European scientific system is still facing challenges in achieving gender equality and gender mainstreaming in research and innovation. In this context, and in line with ERA policy goals and national contexts, the GENDER-NET Plus ERA-NET Cofund aims to strengthen transnational collaborations between research programme owners and managers, provide support to the promotion of gender equality through institutional change and instigate the integration of sex and gender analysis into research and funding programmes. To do so, project partners – a consortium of 16 committed organisations – will join forces to 1) Implement a joint co-funded call for proposals, 2) Design and implement transnational actions on the promotion of gender equality through institutional change and the integration of sex and gender analysis into research, 3) Update and enlarge the mappings and analyses carried out in GENDER-NET on the promotion of gender equality in research and innovation, 4) Carry out a joint assessment of gender differences and bias in access to research grants and define and develop appropriate conditions for promoting equal opportunities in research funding, 5) Promote and disseminate key findings. GENDER-NET will address these goals through 7 work packages and relies on a strong transnational cooperation between partner EU Member States, Associated Countries, and Third Countries, to contribute to the advancement of gender equality in the ERA.

Keywords: gender equality,gender dimension,sex and gender analysis,research funding,transnational activities
Analysis of the performance of innovative nanowire arrays with offset nanoholes Si solar cells for enhanced performance (SolArray)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-06-01
End date: 2023-06-30
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

This proposed project directly address one of the priority areas outlines in EC's Green Deal programme. The usage of textured solar cells to reduce the reflection from the air-solar cell interface, which ultimately enhances absorption, has been widely reported. There is a large number of texturing patterns available such as: pyramids, micropillars, nanowires, nanoholes, plasmonic, etc. The most commonly used patterns have been widely studied and have reached very high levels of optimisations. Nevertheless, these regular patterns have some degree of frequency dependence and hence only a narrow wavelength range optimisation, and thus limits the overall performance. Our preliminary study suggest that absorption efficiency can be further increased by at least 20%, by simply optimising the shape and periodicity of the nanowires. This proposal introduces an innovative combination of the patterns, both circular and noncircular nanowires, additionally including air-holes which increases the solar cell efficiency. Preliminary result also shows that by introducing an offset in the air-hole position, and thus breaking the symmetry, achieves an even higher conversion efficiency, but without increasing the fabrication cost, as simple single-stage mask can be used. By doing this, the improvement on the performance is expected to affect over the whole solar wavelength spectrum. Solar cells with a higher efficiency, but without increased fabrication cost can be a game changer, in supporting UN SDG7, affordable and clean energy. Through hands-on research, the Researcher of this project will enhance his knowledge and skills so can contribute to the European Research Area agenda.

Keywords: nanowire arrays
Sustainable food packaging technology as an alternative to plastic (FRAMTID)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Today’s society has embarked on a non-negotiable path: global sustainability. Every day we want to be better. We research, innovate, change what we do and how we do it. We seek to minimise our footprint in the environment. We want to be active, clean and committed to an environment that is kindly sheltering us. And we do it every day incorporating new customs, new gestures and different ways of being in life. At PackBenefit we always go one step further in what we do and succeed in shaping them with the best eco-friendly packaging in the world. Our containers are designed to transport food and must remain fresh and healthy throughout the supply chain, regardless of their final use. At PackBenefit we have developed this aspect by offering a solution that guarantees the safety of the materials, i.e. the absence of toxicity and the preservation of the organoleptic properties of the food. Today a third of all food produced worldwide is wasted, approximately 1300 million tons. At PackBenefit we know that resources are limited and should be used more responsibly, so we have developed comprehensive packaging solutions that enable the reduction of food waste by ensuring conservation and safety in the production chain through greater integrity in the supply chain and storage of them. FRAMTID trays are natural. They offer the broadest range of working temperatures on the market, without migrating harmful substances to the food or altering its organoleptic properties and the tray does not lose rigidity when heated. On the other hand, they are the best solution among food packaging regarding ecological impact; FRAMTID is 100% compostable.

Keywords: packaging,food waste,compostable,biodegradable materials
Deciphering creativity: A neuro-computational approach to the investigation of creative abilities. (CreHack)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-01
End date: 2023-12-31
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 2
Project status: SIGNED

Creativity is an impressive cognitive ability that makes humans an extraordinary species. To face the timely challenges of our society, creativity is a critical and necessary skill that plays a game-changer role in innovation. Yet, the cognitive and neural mechanisms of creativity are still poorly understood. Formally, creativity is defined as the ability to produce an object/idea that is both original and efficient. Then, creativity should involve an evaluative process of efficiency and originality, interacting with a generative process that generates candidate ideas. Today, a unitary modelling approach is still lacking in the field of creative cognition, and the evaluative process has been poorly explored. Through computational modelling, this proposal aims at investigating the specific role of the evaluative component in the creativity mechanisms. This will allow untangling the different steps of the creative process. The project will use a novel experimental design to develop this model and investigate its neural validity through neuroimaging (fMRI). We expect the main output of this research program to be a neurocomputational model of creativity. We foresee two major impacts: to establish empirical foundations for a general theory of how humans produce creative ideas and to provide open tools to assess creativity in individuals. This proposal is in the position to make a major breakthrough in creativity research by providing a new framework for the investigation of creativity mechanisms. It combines the expertise of the experienced researcher on computational approaches linked to value-based decision-making with the host lab's strength on Neuroscience of Creativity, located in the Paris Brain Institute (ICM), the largest research institute for neuroscience in France.

Keywords: creativity,value system,computational modelling,cognitive profiling,brain imaging
Integrating conspecific odors into tilapia reproductive behaviour (FISHODOR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Portugal
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-06-01
End date: 2019-05-31
Duration (months): 24.0
Total project cost (EUR): 160635.6
EU funding (EUR): 160635.6
Participants: 1
Project status: CLOSED

The aim of FISHODOR is to establish the identity of neural network components of the recently discovered tilapia reproductive pheromone. It will identify pheromone olfactory receptor(s) and their intracellular transduction pathways thereby increasing our understanding of olfactory perception and signal integration of fish pheromones. The project will determine the neuronal cell type (i.e. ciliated, microvillous or crypt-type olfactory receptor neurons) detecting the pheromone, it will establish the transduction pathways (i.e. AC/cAMP or PLC/IP3) involved in its olfactory detection and will identify the olfactory receptor(s) that binds the pheromone. If enough time is available it will attempt to map the neuronal network involved in the neuroendocrine response. The combination of electrophysiology, transcriptomics and molecular biology will bring high degree of novelty to explain the mechanism of action of olfactory receptor and neuronal signal integration.

Keywords: olfactory neurons,transduction pathways,transcriptomics,olfactory receptors,reproductive pheromones,fish
Predicting Response to Depression Treatment (PReDicT)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: United Kingdom
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-2-2015, 2015)
Start date: 2015-10-01
End date: 2019-11-30
Duration (months): 50.0
Total project cost (EUR): 4092630.25
EU funding (EUR): 4092630.25
Participants: 2
Project status: CLOSED

The objective of the Predicting Response to Depression Treatment (PReDicT) project is to conduct clinical, health economic and commercial research to validate the clinical performance and to complete the pre-commercial development of the P1vital PReDicT Test (formerly the eHealth P1vital® Oxford Emotional Test Battery (eH-ETB)), a novel medical device to improve the treatment and management of depression in clinical practice. On completion of the PReDicT project, the P1vital PReDicT Test will be ready for market launch. Depression is a common, serious and in some cases life‐threatening condition, affecting around 350 million people in the world and 11% of EU citizens suffer from depression at some point in their life. It takes 4-6 weeks after starting antidepressant treatment before a physician can detect whether the treatment is working, the majority of patients with depression do not respond to the first treatment they are prescribed and it can take several months before an effective treatment is identified. During this time a patients’ ability to work and function socially is severely impaired, and they can spend many weeks or months absent from work placing a substantial burden on the economy and healthcare resources. The P1vital PReDicT Test addresses this problem by identifying within 1 week of starting treatment whether an antidepressant is working or not which can significantly reduce the time required to identify an effective treatment. Patients benefit from this by returning to good mental health sooner. The aggregated economic cost of depression in the EU is €92 billion, amounting to 1% of the total European gross domestic product. It is estimated that the P1vital PReDicT Test has the potential to reduce these healthcare and economic costs by more than 10%. Thus the PReDicT project focuses on a patient-centric, enabling technology that not only improves efficiency and outcomes for patients but also significantly reduces socio-economic costs.

Keywords: predicting early response to antidepressant treatment for depression