Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Understanding (dis)abilities: considerations on the body and the ethical consequences involved-Undicobatec (UNDICOBATEC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-04-01
End date: 2026-04-01
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: CLOSED

“Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less”. This famous quotation attributed to the scientist Maria Skłodowska-Curie emphasises the importance of «understanding» the realities of life and of understanding them «more and more», and we would add «better and better». In this sense, fear is contrary to science. It hinders its good development and its correct expansion. Regarding human relationships, fear is equally contrary to ethics, because it creates moral attitudes which are usually contrary to the values of respect, integration and inclusion promoted by the different Declarations and Charters of fundamental human rights (the WHO, Europe, Switzerland...). Discrimination, indifference and unfortunately maybe abuse are usually the results of fear and of the misunderstanding of a situation or a condition. Those are the barriers which disabled people have to face, particularly those who have several disabilities. That is the reason why the project «Understanding (dis)abilities», together with the different European policies and strategies implemented in favour of people with disability, wants to reflect on abilities rather than on disabilities. In order to do that, our reflection will start from the abilities linked to the body (the body understood as a global phenomenal reality) as they have been analysed by the different phenomenological ethical, or even under the approach of an interdisciplinary research, pedagogical tendencies of our time. All this with the purpose of arriving at the ethical consequences that such a vision implies in practice, that is to say, in the relationship, support, attention and care of people with disabilities”.

Keywords: real life experience,living body,merleau ponty,phenomenology of disability,ethics answers,attitudes,empathy,abilities
New twin floating platform for offshore wind turbines (SATH)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-02-01
End date: 2017-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Wind power has established itself in recent years as a clean alternative to conventional sources of electrical generation.Reduced costs and wider deployment, especially in the European market, have led over the past decade to its use at sea. Here, the wind resource is larger and more constant, allowing higher unitary power turbines. However, the marine environment itself also imposes a number of restrictions and challenges. The technology that is being deployed now is fixed to the seabed, using different types of foundations, but a large amount of wind resources is in deeper waters, where floating solutions are needed. Because of their initial higher costs, these solutions are still under development, with only three prototypes installed worldwide. The challenge nowadays is to reduce the costs of floating wind turbine structures that will ease the access to a much larger energy potential than available in land, more easily manageable and with lower visual impact. The aim of the SATH project is the demonstration in real conditions of a floating structure for offshore wind which will allow a reduction in LCOE (Levelized Cost Of Energy) over the current floating technology. To achieve this, it is proposed as a first objective the validation and qualifying for this technology, of a 1:3 scaled prototype not only from a technical point of view but also from economic and necessary logistics. The SATH solution is a platform that consists of two cylindrical floats (of prestressed reinforced concrete) which can be manufactured onshore and transported and positioned at the final location in a single mooring point allowing the rotation of the platform around, self-aligning with the wind direction.

Keywords: wind energy,offshore,floating platform,lcoe
Water and Drug Mobility at Silica Surfaces probed with DOSY NMR (MOSUDO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-04-01
End date: 2017-03-31
Duration (months): 24.0
Total project cost (EUR): 185076.0
EU funding (EUR): 185076.0
Participants: 1
Project status: CLOSED

Europe’s pharmaceutical industry is faced with the multitude of lead compounds that are discarded during their development phase. One of the hurdles of most promising drugs is that they have difficulties reaching their site of action in the human body. This insufficient bioavailability results from the complex, poorly understood interplay between drug molecules, water and the surfaces of drug delivery materials and cell membranes. To tackle this challenge, a paradigm shift that recognizes water as headline act is proposed. The physical properties of water drastically change when approaching solid surfaces or cell membranes. Nobel Prize winner Albert Szent-Györgyi even described life itself as “water dancing on the tune of solids”. This research proposal aims to gain understanding of water and drug molecule mobility near silica surfaces. Silica materials in recent years popped up as most promising materials for drug delivery. Unravelling the complex interplay between drug, water and silica surfaces will equip pharmaceutical scientists with a generic toolbox to enhance the bioavailability of newly developed drug candidates. MOSUDO research focuses on probing the mobility of water, amino acids with varying hydrophilicity and a peptide drug in contact with silica. Diffusion-Ordered Nuclear Magnetic Resonance spectroscopy (DOSY NMR) is living spectacular developments and revolutionary sensitivity improvement. This project will take advantage of this development of DOSY NMR to investigate the complex molecule-water-surface interplay with new eyes. Fellowship applicant Dr. Randy Mellaerts can rely on a strong interdisciplinary background in surface chemistry and pharmacy. Acquiring in-depth technical expertise in DOSY NMR and its direct application in pharmaceutical industry will complement his current research profile and allow him to embark at the highest scientific level in a for society very important research area.

Keywords: water,silica,drug delivery,dosy nmr,surface,peptide
Diamond-based nanomaterials and nanostructures for advanced electronic and photonic applications (D-SPA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland,Spain,China,United States,United Kingdom,United Kingdom,United Kingdom
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2016, 2016)
Start date: 2017-04-01
End date: 2023-01-31
Duration (months): 70.0
Total project cost (EUR): 1057500.0
EU funding (EUR): 720000.0
Participants: 10
Project status: SIGNED

We are proposing a 4-year program of knowledge transfer and networking between Aston University, UK (Aston), Cork Institute of Technology, Ireland (CIT), Institute of Nanoscience and Nanotechnology, Spain (ICN2), University of Birmingham, UK (UoB), Zhejiang University of Technology, China (ZJUT), Nanotechplamsa Ltd, Bulgaria (NPL), B&T composites, Greece (B&T), National Institute for Research and Development in Electrical Engineering, Romania (ICPESA), and Teer Coatings Ltd, UK (TCL). The objective of the proposed joint exchange programme is to establish long-term stable research cooperation between the partners with complimentary expertise and knowledge. The project objectives and challenges present a balanced mix between industrial application focused knowledge transfer and development and more far-looking studies for potentially ground-breaking applications of using diamond-based nanomaterials and nanostructures for advanced electronic and photonic applications (D-SPA), including fabrication of diamond nanostructures using 3D printing technology, development of diamond-plasmon hybrid photonic devices and development of biophotonic imaging technology for sensing applications. No one group in Europe can accomplish each work package alone. We have to collaborate with each other in order to gain their skills and expertise in these specific areas.

Keywords: diamond,devices,carbon,sensors
No stress with pArg: Mechanisms of a distinct phospho-mark to coordinate stress response and protein quality control (pArg_deg_signal)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Austria
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-10-01
End date: 2022-09-30
Duration (months): 72.0
Total project cost (EUR): 2499299.0
EU funding (EUR): 2499299.0
Participants: 1
Project status: CLOSED

Cellular proteins are prone to misfolding and aggregation, particularly under harsh environmental conditions. To counteract this danger, all organisms from bacteria to humans evolved sophisticated protein quality control networks. The mechanisms employed in them tend to represent some of the most exciting biochemistry occurring in living cells. In Gram-positive bacteria, the key factors combating protein damage include a specialized protein kinase phosphorylating arginine residues (McsB), the central housekeeping protease (ClpP), as well as a AAA chaperone targeting aggregated proteins (ClpC). We find this quality-control system, organized around a distinct protein phospho mark (phosphoarginine, pArg), a fascinating model to investigate novel principles of dealing with proteotoxic stress. Using an integrative approach, we will delineate the precise role of protein arginine phosphorylation in the bacterial stress response. We will first analyze how this unique modification influences the stability and function of targeted proteins in vitro and in vivo. We are particularly interested in the possibility of pArg serving as a bacterial, ubiquitin-like degradation signal. We will then address the mechanism and regulation of the protein arginine kinase McsB. This analysis will uncover the specificity of the pArg tagging system. Additionally, these studies will reveal enzymatic innovations connected with the pArg chemistry that, due to the dependence of bacterial virulence on McsB, are of pharmaceutical interest. To address the further processing of pArg-modified proteins, we will perform an in-depth structural characterization of ClpC and related AAA disaggregases. A better understanding of the mechanism and regulation of these HSP100 molecular machines is also highly relevant to uncover general principles of how cells deal with toxic protein aggregates and, in parallel, keep control over their potentially dangerous shredding devices.
Transnational Cooperation among ICT NCPs (Idealist2018)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Coordination and support actions
Countries involved: Austria,Estonia,Armenia,Iceland,Spain,Israel,Argentina,Italy,Cyprus,Switzerland,Belgium,Belgium,Bulgaria,Norway,Croatia,Hungary,Slovakia,Moldova, Republic of,Greece,Poland,Romania,Belarus,Georgia,Latvia,France,Czechia,Luxembourg,Guatemala,Mexico,Portugal,Portugal,United Kingdom,United Kingdom
Call: Trans-national co-operation among National Contact Points (H2020-ICT-2014-1, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 4240570.56
EU funding (EUR): 3999995.31
Participants: 37
Project status: CLOSED

The main objective of Idealist2018 is reinforcing the network of National Contact Points (NCP) for LEIT ICT under Horizon2020, by promoting further trans-national cooperation within this network. This cooperation will also include collaboration and networking with similar networks in parallel themes (Security, ENV, Transport, Energy, Health,…etc) especially in the context of joint/coordinated or PPP calls. Special focus is put on helping less experienced NCPs from Member States (MS) and Associated Countries (AC) to access the know-how accumulated in other countries and to apply it in a locally relevant and efficient manner. Furthermore Idealist2018 aims to address national and cross-border audiences, relying on the NCP network mainly established in the MS and AC at national and regional level, to stimulate, encourage and facilitate the participation of current and future ICT research stakeholders in ERA. Special focus is put on newcomers and SMEs, including organisations from MS, AC and third Countries. The activities of Idealist2014 are incremental to the formal NCP responsibilities as they address the international aspects not covered by the nationally funded NCP role. It is built upon: -Experience gained over more than 15 years from the 8 preceding projects covering FP4 to FP7 and now the transition to H2020 -Strengthening NCP cooperation with support for MS, AC and third Countries -Provision of Training and Twinning for less experienced NCPs -Provision of partner search, pre- and full proposal quality support -Focused support for SMEs in the ICT sector and for organisations new to H2020 -Provision of NCP support for countries with S&T international agreements -Promotion of opportunities and Idealist services ensuring a higher NCP visibility

Keywords: national contact points,idealist,leit ict
Tracing Evolution of Auxin Transport and Polarity in Plants (ETAP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Cellular, Developmental and Regenerative Biology
Panel description: Structure and function of the cell, cell-cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Austria
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2018-01-01
End date: 2022-12-31
Duration (months): 60.0
Total project cost (EUR): 2410292.0
EU funding (EUR): 2410292.0
Participants: 1
Project status: CLOSED

Multicellularity in plants evolved independently from other eukaryotes and presents a unique, alternative way how to deal with challenges of life. A major plant developmental module is the directional transport for the plant hormone auxin. The crucial components are PIN auxin transporters, whose polar, subcellular localization determines directionality of auxin flow through tissues. PIN-dependent auxin transport represents a unique model for studying the functional link between basic cellular processes, such as vesicle trafficking and cell polarity, and their developmental outcome at the level of the multicellular organism. Despite decades of intensive research, the classical approaches in the established models are approaching their limits and many crucial questions remain unsolved, in particular related to PIN structure, regulatory motifs and evolutionary origin I propose to start a new direction in my research using an evolutionary perspective. This promises to overcome current limitations and provides not only (i) interesting insights into PIN evolution and diversification, but also (ii) a unique opportunity to study how evolutionary conserved cellular mechanisms of e.g. endocytic trafficking evolved specific plug-ins to make them subject to plant-specific regulations. The characterization of (iii) prokaryotic PIN origin will provide a so urgently needed (iv) entry into PIN structural studies. To achieve these goals, we will also establish novel (v) genetic and cell biological models in the ancestral lineage of the land plants that will be of a great use for any plant evolutionary studies. The intellectual and methodological challenges of such interdisciplinary strategy combining several lower and higher plant models are obvious, but our preliminary results at several fronts promise its feasibility and success to gain deeper understanding of exciting questions on evolution and mechanisms behind the coordination and specification of developmental programs.

Keywords: plant evolution,auxin transport,pin auxin transporters,adaptive development,cell polarity,subcellular trafficking,tissue patterning,growth responses,signalling molecules
Knowledge on International Relations in Russia (RuKNOW)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Russian Federation,United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-01
End date: 2019-08-31
Duration (months): 36.0
Total project cost (EUR): 287825.4
EU funding (EUR): 287825.4
Participants: 2
Project status: CLOSED

Against the backdrop of EU-Russia relations reaching the lowest point since the end of the Cold War, this project is dedicated to understanding what representations and principles underscore Russian policies vis-à-vis the EU, by specifically exploring the relations between Russian academic knowledge of world politics and Russian foreign policymaking. This entails examining the interface between the academy and the world of policymaking, i.e. common and intermediary structures between the two worlds enabling people, training and knowledge to travel between them. None of these areas has been subject to detailed study with regard to Russia. The objectives of the project therefore are: (1) to identify the major concepts, theoretical frameworks and empirical concerns that characterize the Russian study of Russia-EU relations; (2) to pinpoint the dominant narratives on Russia-EU relations produced by the policy world; (3) to identify the structures and frameworks of exchange, homology and mimetism between the academic and policy-making fields in Russia; (4) to identify the content and form of the actual exchange of knowledge and expertise between the academy and the field of policymaking. This close focus on Russia makes it essential for this study to be carried out under the Global Fellowship framework. The meeting of research objectives and the achievement of training goals require the development of ties and collaboration with the Russian academia and continued exposure to Russian policy-making environment. The innovative nature of this cross-disciplinary project consists in proposing an alternative approach to examining Russian foreign policy and in the application of a rich methodological framework to capture the different dimensions - institutional, cultural, ideological - of the knowledge-policy interface. The carrying out of this research at academic institutions in Russia and the EU will enhance scholarly collaboration across the current political divide.

Keywords: international relations,russia,sociology of knowledge,eu russia relations,foreign policy
Harvesting airborne wind energy using rigid kites. (NextWind)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Norway
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-06-01
End date: 2017-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Airborne wind energy (AWE) is a renewable energy source with a huge potential, but remains yet to be harnessed at a commercial scale. Commercialization of AWE will contribute in reaching the committed share of 27% renewables in Europe by 2030. The wind energy is stronger and more steady at higher altitudes, which means that AWE can be installed in locations where wind turbines are not viable. AWE can also be used in locations where conventional wind turbines have a negative impact on the visual environment. Contrary to conventional wind turbines, kite turbines have a very small footprint on the ground and are hardly visible up in the air. A complete construction of a kite turbine requires only 10% the mass of a conventional wind turbine and yearly operational hours can double due to high altitude operation. The Norwegian based AWE producer, Kitemill has demonstrated autonomous operation of their 30-kW kite turbine in operational environment at their test site. Their unique features for succeeding in commercialization of kite turbines: • The first airborne wind energy supplier to feature vertical take-off and landing (VTOL) solution. The advantage with a VTOL system is a minimized landing platform since it only need to be as wide as the wingspan of the kite. • Customer secured for a demo park consisting of five 30-kW kite turbines. • The first company to have obtained permanent operating license in designated areas issued by National Aviation Authorities. • Commercialization strategy will start with the 30-kW kite turbine to obtain a high number of operational hours at a smaller scale, which will reduce risk for the customers when introducing a new energy technology. Full scale levelized cost of energy is calculated to 2,8 c€/kWh, which is much cheaper than current wind turbines.

Keywords: kite turbine,airborne wind energy awe,wind energy