Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Pathogen-informed Resistance to Oomycete diseases in Ecosystems, Agriculture and Aquaculture (PROTECTA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy,Norway,Sweden,Sweden,France,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-08-01
End date: 2023-01-31
Duration (months): 54.0
Total project cost (EUR): 3992284.44
EU funding (EUR): 3992284.44
Participants: 9
Project status: CLOSED

The oomycetes are a distinct lineage of Eukaryotic microbes that resemble fungi, but are genetically related to the heterokont (brown) algae. Oomycetes have a worldwide distribution and are destructive and highly adaptable pathogens, infecting vascular plants, fish, insects fungi and occasionally humans. Notorious crop damaging pathogens such as the potato late blight pathogen Phytophthora infestans, vegetable root rots and (re)-emerging diseases such as fish saprolegniosis and Sudden Oak Death are global threats to food security and natural ecosystems. Comparative genomics in the oomycetes reveals major classes of effector proteins used by pathogens to manipulate hosts that can also be recognised by host immune systems. The major challenges in oomycete research are to identify the precise biochemical functions of major pathogenicity determinants (such as effector proteins) and host immune responses (such as plant resistance genes) and translate this research into durable disease control in agriculture, ecosystems and aquaculture. We have assembled a multidisciplinary, inter-sectoral team including some of Europe’s leading researchers in the field, SMEs, multinational companies and government agencies, to train the next generation of European researchers to address these challenges. PROTECTA aims for a large-scale quantification of effector gene expression and protein abundance during the infection process of oomycetes that infect diverse crop, tree, and fish hosts. We will advance our fundamental understanding of the genetics and biochemistry of host-oomycete interactions on an unprecedented scale. We will exploit this data to identify new mechanisms of host resistance and work directly with plant breeding and aquaculture companies to translate our results into new crop varieties with durable resistance, new ways to protect fish in aquaculture, and new biological control methods to protect agricultural systems and reduce European dependence on chemical pesticides.

Keywords: comparative proteomics,omics,oomycetes,molecular host microbe interactions,effectors,plant pathology,resistance genes,disease control,biological control,forest health
Towards Demonstration of Photonic Payload For Telecom Satellites (OPTIMA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling European competitiveness, non-dependence and innovation of the European space sector
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Spain,Belgium,France,France,United Kingdom,United Kingdom
Call: Maturing satellite communication technologies (H2020-COMPET-2016, 2016)
Start date: 2016-11-01
End date: 2019-10-31
Duration (months): 36.0
Total project cost (EUR): 2836225.0
EU funding (EUR): 2819913.75
Participants: 8
Project status: CLOSED

OPTIMA aims at demonstrating photonic payloads for telecommunication satellites by joining the efforts of industrial and academic European actors from both the worlds of space and terrestrial communications. In the near future, a major increase in telecoms satellites capacity is required to address the challenges of the Digital Agenda for Europe, and to remain in line with the skyrocketing evolution of terrestrial communications, in a globally connected world. A major technological breakthrough is needed to meet the capacity increase objectives within the mass, size and power envelope allowed by the foreseen evolution of launchers and satellite platforms. Photonics has largely contributed to the revolution of Information Technology for ground applications and is the most promising technology to overcome the issues faced by Satcoms, thanks to the compact, lightweight and low-power nature of optical-fibre based equipment. However, great efforts are required to bring these benefits to the world of telecoms payloads as all the photonics equipment used on ground need to be adapted for space. In OPTIMA, Airbus Defence and Space (UK, FR), a world-leading satellite prime manufacturer, will define, assemble and a test photonic payload demonstrator based on building blocks developed, adapted for space and provided by other members of the consortium: DAS Photonics (ES), Linkra (IT), SODERN (FR), IMEC (BE) and Polatis (UK). By gathering all these actors around a concrete project, in a real-world industrial environment, OPTIMA will provide a strong initial impulse to make photonics technology available to the Satcom industry and pave the way towards an in-orbit demonstration as early as 2020. This will not only allow the European space industry to address the challenges of the DAE 2020, but also strengthen its position in a very competitive, worldwide market and create new opportunities for each of the members of the consortium (new applications, products and markets).

Keywords: high speed broadband delivered via satellite is key to complete the coverage of european citizens unserved or underserved by high speed terrestrial network
Structure-activity relationships of an emerging family of fungal lytic polysaccharide monooxygenases (ARTFUL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-04-01
End date: 2019-03-31
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

During the past century, fossil-based hydrocarbons have been the main source of energy and chemicals, but in addition to be an unsustainable resource, they have led to important environmental concerns such as rising CO2 emissions. The great challenge for our societies is to develop alternative approaches for the sustainable production of energy and materials; the bioconversion of lignocellulosic biomass is one of them. Nevertheless, the physical and chemical recalcitrance of the biomass is the main obstacle to its cost-effective conversion as huge amounts of degrading enzymes are still required. Therefore, a significant improvement in enzymatic degradation is necessary, which involves enlarging the catalytic toolbox. By doing a large scale screening of the secretomes of a substantial fungal collection, the host organisation has shed light on the first member of a new family of lytic polysaccharide mono-oxygenases (LPMOs). LPMOs have been shown to boost the efficiency of cellulases industrial cocktails, thereby greatly reducing the financial and environmental penalties associated with the use of recalcitrant polysaccharides as a feedstock and, moreover, placing LPMOs at the center of considerable research interest. The objective of the ARTFUL project is the functional and structural characterization of the representative members of the new fungal LPMO family. The 6 years’ experience of the French fellow in the glycobiology field (biochemistry, enzymology, structural biology) combined with the expertise of Aix-Marseille University (France) in fungal omics form a solid basis that will be reinforce by the collaborations of experts. The quality of the hosting arrangements will maximise the training opportunities of the fellow and is suited for the two way transfer of knowledge. Acquired generated knowledge will provide a robust functional context to bioinformatic-based predictive biology as well as new enzymatic tools for subsequent industrial applications.

Keywords: filamentous fungi,plant cell wall,plant biomass,carbohydrates,oxydative enzymes
FIELDTECH: Technology for next-generation characterization of optical fields (FIELDTECH)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Coordination and support actions
Countries involved: Germany
Call: FET Innovation Launchpad (H2020-FETOPEN-2018-2019-2020-4, 2020)
Start date: 2021-04-01
End date: 2022-03-31
Duration (months): 12.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The proposed project is dedicated to bringing technology for next generation characterization of optical fields to a market level. The technology, based on recent innovations at LMU, will facilitate simple optoelectronic devices, for e.g. carrier-envelope-phase (CEP) measurements, enabling the characterization of few-cycle pulses at a single laser shot level. Contemporary CEP-meter techniques, i.e. the f-2f interferometer and Sterero-ATI technique, have limitations, including they do not easily offer extension of single-shot measurements towards increasing repetition rates (beyond 100 kHz), have limited operation wavelengths, or involve a sophisticated apparatus, which is bulky and expensive. Based on our recent innovation, the realization of a simple phase meter that consists of only a few components and can even work in ambient air, we propose to explore bringing this and also its related field-metrology technology to the market to overcome such limitations. We aim to improve the long-term stability of the device, to enhance the signal sensitivity, and to decrease the temporal response time for high-repetition single-shot CEP detection and retrieval. These include a new design of the device structure, a proper encapsulation of the core device including electromagnetic shielding, the incorporation of fast electronics components, and the development of a user-friendly software. The newly developed device will undergo a series of tests with different ultrafast laser sources both in the near and mid-infrared wavelength range and at repetition rate up to at least 100 kHz. In parallel to the S&T development, we will carry out the ‘go-to-market’ activities, which include securing the IP, standardization and modulation of the product, the analysis of worldwide potential market, discovery of supply and distribution channels, and formulation of sales strategies.

Keywords: characterization of ultrafast laser fields,carrier envelope phase,petahertz electronics
LightSense's Breakthrough medical device for aesthetic healthcare (CLEAN SLATE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel,United Kingdom
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-06-15
End date: 2021-06-14
Duration (months): 24.0
Total project cost (EUR): 3017625.0
EU funding (EUR): 2112337.5
Participants: 2
Project status: SIGNED

Founded by a world-leading physicist and a track-record technology entrepreneur, LightSense has developed and patented a breakthrough technology that dramatically improves non-invasive dermatological healthcare. We plan to bring this technology to market through skincare clinics. We will initially offer aesthetic dermatology services focused on exogenous and endogenous pigments because (1) there is large and growing market, over 100 million people - and growing - are looking for a solution; (2) current treatment offerings are ineffective, painful, damaging to skin tissue, and very lengthy; (3) our technology breakthrough positions us to offer a significantly better treatment experience; (4) we already have significant intellectual property protection that enables successful go to market. With success in treating pigmentation disorders, we intend to quickly expand our offer, establishing industry-wide and academically-recognised solutions for many laser dermatology procedures. This project focuses on finalising product development and testing, and gaining regulatory approval through clinical studies, and final commercialisation of the innovation.

Keywords: pigmentation disorders,aesthetic healthcare,dermatology
Unaccompanied Minors Automatic Forensic Age Estimation (UMAFAE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-03-01
End date: 2024-02-29
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: SIGNED

In recent years, the European Union is facing an unprecedented wave of mass migration and governments and institutions are struggling to keep up. One particular difficult topic is the age estimation of unaccompanied minors: in 2017 there were more than 20.000. Around 90% of them were between 15 and 17 years old and most of them were undocumented. Several scientific publications are addressing the issue of age estimation. The focus is usually a specific anatomical region or a set of them. Regions are then analyzed within different medical image modalities to provide an age estimation. However, the limitations of state-of-the-art methods are as follows: i) subjectivity and lack of sound validation tests; ii) the majority is error-prone and time-consuming; iii) limited sample size; iv) vast population-specific differences in the patterns of maturation, and v) lack of reliability and reproducibility. UMAFAE’s goal is to develop AI-based algorithms that determine the age of a person. This challenging proposal is achievable due to the ER (Dr. De Luca) and supervisor (Dr. Ibáñez) profiles. The ER is one of the most recognized European experts for age estimation, with a vast experience in forensic practice. Dr. Ibáñez is a world pioneer in the application of Artificial Intelligence techniques to Forensic Anthropology, with the largest number of publications and patents in this multidisciplinary field. The know-how of Panacea’s research team in different fields (from forensic and medical imaging to deep learning and computer vision), the equipment and facilities of the University of Granada (UMAFAE’s partner), together with a large list of data providers (agreements with six Universities) and the support of the main leading international experts in the field (Drs. Cameriere, Schmeling, Viner, Márquez-Grant and Garamendi) compose a unique environment to accomplish these ambitious and groundbreaking objectives. The project includes a clear plan for technology transfer.

Keywords: legal medicine,forensic anthropology,forensic radiology,artificial intelligence,machine learning,biological profile,medical engineering and technology
Flows Unveiled: Multimodal Measurement in Opaque Two-Phase Flows (OpaqueFlows)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Netherlands
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-05-01
End date: 2022-10-31
Duration (months): 66.0
Total project cost (EUR): 1955112.5
EU funding (EUR): 1955112.5
Participants: 1
Project status: CLOSED

Dispersed multiphase flows are encountered in nearly every process in nature and industry; examples include sediment in rivers, catalysts in reactors and blood flow. Despite their relevance, it is currently difficult to accurately and efficiently model these flows. The opacity of the flows, even at moderate volume fractions, renders the common optical flow measurement tools useless. As a result, very little high-quality data is currently available to develop (numerical) models. In this project, I lift the veil that covers multiphase flows. I do this by bringing together four flow measurement modalities, based on ultrasound, magnetic resonance, X-ray and advanced optical imaging. These are each applied to three benchmark flows, impenetrable to common (optical) techniques. This project will be the first focused effort to systematically apply these techniques to the same three benchmark flows. These benchmarks are: (1) a turbulent flow with heavy particles, (2) a laminar flow with relatively large particles and (3) a laminar flow with small particles showing non-Newtonian behaviour. These three flows represent archetypical flows from nature and industry, each pertaining to particular open questions in the field of fluid mechanics. The combined velocity and concentration field data resulting from this set of experiments will be vital in assessing and improving each of the techniques: direct comparison will allow evaluation of the performance and show the effect of acquisition and processing parameters on the accuracy. Detailed simulations using the exact same conditions will serve as further reference. Combined with the multi-modal experimental data, this will give breakthrough insight in the underlying physics of each of the benchmark flows. This in turn will lead to better multiphase flow models, which are demanded by a wide range of application areas (e.g. process technology, dredging, food and cosmetics industry, and hemodynamics research).
Integrated Photonics for the next generation of autonomous Vehicles using InP technologies (DRIVE-In)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Spain
Call: Innovative Training Networks (H2020-MSCA-ITN-2019, 2019)
Start date: 2019-10-01
End date: 2023-09-30
Duration (months): 48.0
Total project cost (EUR): 1005503.04
EU funding (EUR): 1005503.04
Participants: 2
Project status: SIGNED

Photonic integration is emerging as a new standard for providing high-performance, miniaturised optical systems for a wide range of applications, among others in the thriving sector of vehicle autonomy. However, the potential of the sector is currently hampered by the availability of accurate simulation and validation tools for optoelectronic Photonic Integrated Circuit (PIC) design, which is why an exceptional improvement of PIC software tools and better modelling procedures and simulation tools for Process Design Kits (PDKs) are of the utmost importance. To foster the adoption of photonic based solutions in the automotive industry, the academic and industrial partners of DRIVE-In will work synergistically to generate a cohort of four young scientists with advanced inter-disciplinary skills in hybrid optoelectronic circuit designs and software simulation and modelling of Indium Phosphide-(InP)-based PICs. DRIVE-In will train four ESRs at two leading European academic institutions and three industrial companies, thus forming a strong interdisciplinary network between industry and technical sciences to overcome specific barriers in the intersection of the integrated photonics sector and the automotive industry. With combined skills in e.g. hybrid optoelectronic circuit designs and software simulation and modelling of InP-PICs, the DRIVE-In ESRs will contribute to overcoming the challenges related to hybridisation of integrated photonics and microelectronics, increasing PIC complexity, needs for high-performance FSO links and for software simulation and fast-generation layout models. The availability of professionals combining the DRIVE-In skills will directly fuel emerging optoelectronic PIC-based innovation and ensure its exploitation by the photonic industry in the automotive sector. Additionally, unique career opportunities will arise for the professionals involved in this technological step change in advanced InP-PIC design and simulation.

Keywords: photonic integrated circuits,indium phosphide,process design kits,hybrid systems,optoelectronic,photonics simulation and modelling tools,automotive,advanced driver assistance systems,lidar
Repurposing manufacturing lines for providing medical and other products and services in case of spiking demand times (RESERVIST)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced manufacturing and processing
Action type: Innovation actions
Countries involved: Spain,Italy,Italy,Spain,Belgium,Belgium,Belgium,Finland,Greece,Finland,France,Netherlands
Call: Repurposing of manufacturing for vital medical supplies and equipment. (H2020-SC1-PHE-CORONAVIRUS-2020-2-NMBP, 2020)
Start date: 2020-12-01
End date: 2023-05-31
Duration (months): 30.0
Total project cost (EUR): 6186787.5
EU funding (EUR): 5044851.75
Participants: 17
Project status: SIGNED

RESERVIST aims to establish ‘reservist cells’ that in times of crises can be activated within 48hrs to switch to manufacturing medical products and services that are spiking in demand. Such a ‘reservist cell’ will consist of (i) a backbone network of core companies for manufacturing and testing; (ii) an extended network for further capacities (eg local provision, packaging, distribution, customization,…); (iii) a digital coordination platform and (iv) a pool of experts from the companies of the network. These cells will become operational in case of an emergency/pandemic but to make economic sense, the same approach of rapid flexibility and adaptability will be used to deal with surging demand in ‘normal circumstances’. To realise this concept, we will first work on three levels individually: network level, connected manufacturing/digital manufacturing level and technical level, the latter referring to tweaking manufacturing lines, developing required materials and establishing links with testing/certification. Next, we will demonstrate the repurposing of 5 existing manufacturing lines within 48hrs towards manufacturing of ‘textile PPE’ (surgical and respiratory face masks, medical aprons) and ‘respiratory ventilators’ (invasive and non invasive) that comply with necessary testing and certification and proceed with the embedment of the reservist cells at the partners in the network. We will develop blueprints for further take-up and replication of the concept to other sectors. Within the project we will develop two replication demos: ‘disinfection equipment’ and ‘emergency medical equipement’. To support the Cells we will tap into the worldwide maker community and into relevant OITBs and networks. The consortium is strongly industry-driven, including 4 LE and 7 SMEs coming from 7 EU countries. To maximise impact, we will extend our partner network and our Impact Support Group (18 Support Letters provided at proposal stage).

Keywords: respiratory ventilators,medical face masks,respiratory face masks,digital manufacturing