Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
At the fringes of the Republic of Scientists: the East-West routes of scientific communication in Europe in the age of experiment (1650-1680) (EASTWAYS OF SCIENCE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2007-2-2-ERG, 2007)
Start date: 2008-04-01
End date: 2011-03-31
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

Eastways of Science aims to carry on and to improve Highways of Science, the project the researcher worked at thanks to a Marie Curie Intra-European Fellowship at the Centre A. Koyré in Paris from July 2005 to June 2007. Highways of Science meant to construct a prototype of a multitask data-base user-friendly, that takes into account evidence gathered from scientific and learned correspondences (personal biographies, scientific institutions, instruments, natural specimina and objects, places related to scientific practices) so as to define and highlight the contents, the networks and the ways of transmission of cultural and scientific information in early modern Europe. Eastways of Science aims to extend Highways of Science in two different respects. As to space, because it takes into account the so called «fringes» of the «Republic of letters»: the Mitteleuropa areas, especially Poland and the Habsburg Empire’s «periphery» (Bohemia, Moravia, Hungary and Rumania). As to time, because it looks further at the second half of the 17th century, the age when the experiment became the knowledge basis of modern natural philosophy. Most of all, Eastways of Science project means to climb over Highways of Science limits and difficulties by creating an electronic platform, an on-line interactive environment XML-based, that for the first time applies the Web2 system resources to an electronic archive of scientific-historical interest. In this case too, information will be arranged and available in a spatial and geographical fashion, so as to construct a map of the information fluxes in the western European cultural space, following the model of a traffic stream visualized on a luminous screen. The researcher and the University of Rome La Sapienza purpose to cooperate with the project academies and research institutes in Poland, Hungary, Czech Republic, Slovack Republic and Romany who are working on electronic editions of national sources of historical interest.

Keywords: history of science,social history,modern history,data management,archivistic
Constructive and Disruptive Effects of Noise in Nonlinear Systems with Hysteresis (CONDISHYST)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Romania
Call:  (FP7-PEOPLE-2007-4-3-IRG, 2007)
Start date: 2008-05-01
End date: 2012-04-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

This project is aimed at providing a comprehensive analysis for stochastically driven hysteretic systems from various areas of science. While the quasi-static analysis of hysteretic systems has reached some degree of maturity, the stochastic and dynamic analysis is currently under major developments. Although the precise meaning of hysteresis might be different from one area to another, its origin is commonly due to the multiplicity of metastable states exhibited by that system. The physical systems are usually affected by internal or external noise, leading to a stochastic behavior of the system's output. The main objectives of this project are to develop methods for the stochastic analysis of hysteretic systems, to provide a comprehensive and unitary study of them, and to apply the results of this analysis in various areas of science and technology, such as magnetic data storage, photonic devices, shape-memory alloys, and computational neuroscience. The analysis and the control of the disruptive effects of noise in nonlinear systems with memory play a major role in the further development of the data storage technology. This project is expected to provide pertinent solutions to the current challenges related to the thermal stability of the recorded data and to help designing future memory devices. While it is mostly experienced as a disruptive effect, noise can also have a constructive role in hysteretic systems, activating a resonance response. Recent studies on nonlinear systems proved that such phenomena are quite common and their applications range from signal processing to climate models. This phenomenon is generally known as coherence resonance, when is solely induced by noise, and stochastic resonance, when an external oscillatory signal is present. Our analysis is also aimed at exploring the coherence and stochastic resonances in nonlinear systems with hysteresis and at deriving the rigorous conditions under which such resonance phenomena are possible.

Keywords: noise,coherence resonance,stochastice resonance,magnetic storage,optical storage,nonlinear dynamics,hysteresis,multiscale modeling,spintronics,thermal relaxation,graphs,stochastic analysis
The elucidation of the nuclear receptor gene regulatory network in mouse microglia (MNRGN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2007-4-3-IRG, 2007)
Start date: 2008-04-01
End date: 2012-03-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Nuclear receptors (NR) constitute a large transcription factor (TF) family with ~50 NRs identified in human or mouse. NRs have crucial roles in multiple tissues and biological processes. Consequently, misregulation of NR gene expression has been linked to several severe pathologies including cancer and neurodegenerative diseases. Despite their pathological importance, the core NR gene regulatory network (i.e. the protein-DNA interactions or PDIs controlling the expression of NR genes) has been very poorly studied. We will initiate the elucidation of the NR gene regulatory network by focusing on primary microglial cells as a non-transformed, and homogeneous model system. Microglia are poorly characterized macrophage-like brain immune cells, which may have both neurotoxic and neuroprotective properties. The majority of NRs exhibit a very dynamic expression profile in activated macrophages. Together with our preliminary data, this suggests that NRs may play a central role in microglial gene regulatory networks as well. The biological question of this proposal is to understand “which, when, and how NRs are expressed in microglia in response to neurotoxic stimuli”. We will (1) identify the temporal gene expression profiles of NRs in activated microglia; (2) identify the TFs controlling differentially expressed microglial NRs by uniquely combining two novel technologies (chromosome conformation capture and high-throughput PDI screening), whose respective co-inventors will both be involved in the project; and (3) experimentally validate the detected PDIs in microglia using siRNA and ChIP. The resulting list of high-confidence PDIs will be used to generate a first microglial NR gene regulatory network. The latter can be used for future modeling efforts to predict how the network will behave under distinct physiological conditions, or how to manipulate the network such that the neuroprotective properties of microglia are stimulated and its neurotoxic properties suppressed.

Keywords: molecular genetics,genomics,genetic engineering,modelling networks
Polyelectrolyte nanocomplexes (PE-NANOCOMPLEXES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Hungary
Call:  (FP7-PEOPLE-2007-2-2-ERG, 2007)
Start date: 2009-02-15
End date: 2012-02-14
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

The major goal of the proposed project is to facilitate the applicant’s reintegration to his home institute after a successful Marie Curie training period at the Surface Chemistry, Dept. of Chemistry, KTH, Stockholm. To reach this goal the host (Eötvös Lorand University, Budapest) offers a permanent position for him and provides the infrastructure necessary to implement the proposed research project. The proposed research project consists of two independent work packages. The first work package aims at developing and applying a nanoprobe technique to determine the optimal structure of DNA-polyelectrolyte complexes, which is an important step required to increase the efficiency of current non-viral gene delivery systems. The second work package will map the effect of multivalent ions on the interaction of a flexible polyelectrolyte and an oppositely charged surfactant, which will provide information how the strong ion-ion correlations, introduced by the multivalent ions, affect surfactant/polyelectrolyte self-assembly. Finally, the reintegration grant will allow the researcher to transfer his new competences (related to modern surface characterization techniques, e.g. DPI, AFM, QCM-D, ellipsometry) to the host institution of the reintegration period and to the wider audience of its students.

Keywords: surface chemistry,polyelectrolyte/surfactant interaction,gene delivery
The Millimeter Wave Circular Dichroism Spectroscopy as a Powerful Tool for the Exploration of Molecules (PRAMICIDIS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Czechia
Call:  (FP7-PEOPLE-2007-2-2-ERG, 2007)
Start date: 2009-01-01
End date: 2011-12-31
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

By one of very important key for understanding biological processes is knowledge of structure of bio-macromolecules. These molecules have optical activity asymmetry which is connected with macromolecule structure and they absorb across the millimeter wave part of the spectrum due to collective vibrational modes. It is supposed that there will also be significant circular dichroism - differential absorption of left- and right-handed circularly polarized light. Since the biological material is chiral, this millimeter wave circular dichroism (MCD) spectroscopy would be a powerful tool for exploration of biomolecules. The very first millimeter wave spectrometer will be built. In addition, a packet of programs for driving the whole spectrometer and for analyzing obtained spectra will be developed. The last scientific objective will be measurements on interesting chiral molecules. The obtained MCD spectra will be proof that the constructed MCD spectrometer is sensitive biospecific tool. The experimental MCD spectra will also be compared with the simulated MCD spectra for determination of absolute configuration of molecules.

Keywords: millimeter wave,spectroscopy,biomolecules,circular dichroism,chirality,vibrational modes
Wireless Sensor Networks for the Protection of Critical Infrastructures (WSAN4CIP)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Pervasive and Trustworthy network and service infrastructures
Action type: Collaborative project
Countries involved: Germany,Germany,United Kingdom,Portugal,Hungary,France,Sweden,Spain,Spain,Germany,Germany
Call:  (FP7-ICT-SEC-2007-1, 2007)
Start date: 2009-01-01
End date: 2011-12-31
Duration (months): 36.0
Total project cost (EUR): 4020996.0
EU funding (EUR): 2775000.0
Participants: 12
Project status: CLOSED

The goal of WSAN4CIP is to substantially advance the technology of Wireless Sensor and Actuator Networks (WSANs) beyond the current state of the art and to apply this technology to the Protection of Critical Infrastructures. In particular, the WSAN4CIP project will apply these advanced wireless and sensor network developments to the management of power generation and distribution infrastructure management systems, which is one of the most demanding applications for wireless infrastructure, to demonstrate the appropriateness and effectiveness of the WSAN4CIP project results. The project will contribute to making networked information and process control systems much more secure and resilient. The highly distributed nature of Wireless Sensor and Actuator Networks (WSANs) boosts their ability to survive malicious attacks as well as accidental and operational failures. It makes them dependable in critical situations, when information is needed to prevent further damage to Critical Infrastructures (CIs). As WSANs are inexpensive to deploy and self-organizing it is both practical and efficient to consider an emergency extension of the WSAN as a first reaction to CI problems. The WSAN4CIP project will show how exploiting these features make WSAN an ideal mechanism to improve situation awareness of managing tools for critical infrastructures. A main challenge of the WSAN4CIP project is that the current state-of-the-art technology for WSANs is not sufficiently dependable for CI use. The WSAN4CIP project will: * Design new sensor node protection mechanisms to improve their dependability * Develop innovative dependable networking approaches for WSANs * Create dependable services to run on top of WSANs that ensure a controlled degradation of information in case of failures rather than total management system failure. The project will also develop design methodologies, and define an open interface to ensure interoperability with existing CI management applications.

Keywords: critical infrastructure protection,power plants,wireless sensor networks
Protection And tRuSt In FinanciAL infrastrcutures (PARSIFAL)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Pervasive and Trustworthy network and service infrastructures
Action type: Coordination and support actions
Countries involved: Spain,Ireland,United Kingdom,Germany,Netherlands,Switzerland
Call:  (FP7-ICT-SEC-2007-1, 2007)
Start date: 2008-09-01
End date: 2010-02-28
Duration (months): 18.0
Total project cost (EUR): 688848.0
EU funding (EUR): 600000.0
Participants: 6
Project status: CLOSED

The European Programme for Critical Infrastructure Protection underlines that &quot;since various sectors possess particular experience, expertise and requirements with CIP, EPCIP will be developed on a sector-by-sector basis and implemented following an agreed list of CIP sectors&quot;. The European Critical Infrastructure Directive puts forward in Annex 1 a list of 11 critical infrastructure sectors that include Financial CI sector. Protection And tRuSt In FinanciAL infrastructures (PARSIFAL) proposal is targeting this ambitious objective concerning how to better protect FCI and information infrastructure that link FCI with other Critical Infrastrucutre in Europe. PARSIFAL has the following objectives: 1) Bringing together CFI and TSD research stakeholders;2)Contributing to the understanding of CFI challenges;3)Developing longer term visions, research roadmaps, CFI scenarios and best practice guides;4)Co-ordinating the relevant research work, knowledge and experiences. The need to create forums at EU level is specifically mentioned in order to facilitate exchanges of views on general and sector specific CIP issues. PARSIFAL is aiming to bring together all financial critical infrastructure stakeholders in the public and private sphere which would provide the MS, Commission and the industry with an important platform through which to communicate on whichever new CIP issue arise. Furthermore, PARSIFAL Forum would asses a possibility of the creation of EU FCI related industry/business associations. The success of PARSIFAL will be largely based on its ability to build a large consensus in the financial, security industrial and scientific community. This will require the ability to contact and involve a large number of SME’s that are working in this field, as well as Academia and Research Organisation all over Europe and bring them together with all the relevant national or regional CIP and Financial sector actors.

Keywords: critical infrastructure protection,privacy,trust,financial infrastructures,critical information infrastructures,ict
Tool for sistemic risk analysis and secure mediation of data exchanged across linked CI information infrastructures (MICIE)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Pervasive and Trustworthy network and service infrastructures
Action type: Collaborative project
Countries involved: Italy,Luxembourg,Poland,Israel,Belgium,Portugal,United Kingdom
Call:  (FP7-ICT-SEC-2007-1, 2007)
Start date: 2008-09-01
End date: 2011-02-28
Duration (months): 30.0
Total project cost (EUR): 3496456.0
EU funding (EUR): 2448164.0
Participants: 12
Project status: CLOSED

MICIE project, being in line with EU initiative to establish a Critical Infrastructure Warning Information Network (CIWIN), will design and implement a so-called "MICIE alerting system" that identifies, in real time, the level of possible threats induced on a given CI by "undesired" events happened in such CI and/or other interdependent CIs. Whenever such events occur, the MICIE alerting system will support the CI operators providing them with a real time risk level (e.g. expressed in a chromatic scale such as green, yellow, red). The alarm conditions will be evaluated by means of an on-line prediction tool making use of properly designed abstract CI models. The CI model will make use of hierarchical modelling in order to evaluate the "level of interdependency" existing among the different CIs, which will be characterized through proper “thresholds” values. The MICIE alerting system will also include a proper discovery, communication infrastructure able to operate in a heterogeneous CI framework, aiming at discovering the "sensible" data in the different CIs, at translating them in CI-independent metadata and transporting them via a communication network. Key activities of MICIE project will be: 1. Design and analysis of qualitative and quantitative interdependency metrics and indicators accounting the service continuity and data integrity of the ICT infrastructure of the CIs 2. Design and analysis of a hierarchical modelling framework for interdependency analysis based on the integration of heterogeneous modelling techniques 3. Development of an on-line (real-time) “cascade failure induced” alarm level predictor able to provide a qualitative indication of the actual level of exposure to cascade failure 4. Design of a suitable commutation network able to assure availability, authenticity, integrity, of metadata exchanged 5. Validation of the interdependency alarm -predictor system on the infrastructure of an Electric Company, Israel Electric Corp, partner.

Keywords: critical infrastructure,vulnerability,risk analysis,modelling,bayesian network,resilient,cascading effects,interdependency
Scanning for Emerging Science and Technology Issues (SESTI)

Framework: FP7 — Cooperation
Programme: Socio-economic sciences and Humanities
Destination: Foresight activities
Action type: Collaborative project
Countries involved: Netherlands,United Kingdom,Austria,European organisations area,Netherlands,Malta
Call:  (FP7-SSH-2007-1, 2007)
Start date: 2008-10-01
End date: 2011-06-30
Duration (months): 33.0
Total project cost (EUR): 733733.2
EU funding (EUR): 628978.0
Participants: 6
Project status: CLOSED

Today’s societal developments are often influenced by improbable events with high impact. Recent examples are the “cartoon quarrel” and developments impacting energy security. These events are preceded by “weak signals” which are only partially discussed in policy, if at all, and rarely acted upon. The increasing complexity and uncertainty is reflected in the growing demand for tools for anticipatory intelligence, such as scenario analyses, Delphis and modelling and simulation tools. Several countries, Finland, UK and the Netherlands, have initiated horizon scanning projects to identify disruptive events that are not on the RADAR of policy yet. The overall goal of the project is to contribute to the development of an effective system for the early identification of weak signals of emerging issues. For that a weak signals pool, integrating several scanning tools in a wiki to collect and disseminate the information, will be set-up. Additional to its European focus, potential links with national actors and platforms are planned, making use of existing networks such as ForSociety (several of the project members are ForSociety members), to feed the project outputs into European and national policy processes. Beneath this overriding goal is the desire to initiate momentum at national and European level to pro-actively address emerging issues. Next to its practical goals, this project also aims at developing and improving new tools and methods for weak signals of emerging issues to improve detection and the operationalisation of methods using a case oriented approach to contribute to the overall Bluesky call issues. To exploit resources most effectively, this project builds on existing structures and competencies in foresight and horizon scanning in place at national level (above examples), and intends to add value by by improving existing resources, providing new strategic information and creating synergies exploiting complementarities between initiatives.

Keywords: weak signals,horizon scanning,emerging issues,science & technology,policy support