Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
6G Non Terrestrial Networks (6G-NTN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Smart Networks and Services
Action type: Research and Innovation actions
Partnership: SNS (JU-JTI)
Countries involved: Italy,France,Luxembourg,Switzerland,Sweden,Spain,Germany
Call: Communication Infrastructure Technologies and Devices (HORIZON-JU-SNS-2022, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 5195871.26
EU funding (EUR): 4797967.64
Participants: 16
Project status: SIGNED

The 6G-NTN project aims at researching and developing innovative technical, business, regulatory, and standardization enablers to achieve full and seamless integration of the Non-Terrestrial Network (NTN) component into the 6G system and establish the European leadership in this domain. The vision is to extend coverage, resilience, and sustainability of next generation mobile networks, meeting needs and expectations of both vertical and consumer market segments, while unleashing new value chains and creating broad societal impact. The proposed concept of full-fledged integration of the NTN component into 6G leverages multiple key project outcomes that will pave the way for a service roll-out in the 2030-35 time frame: - a sustainable and resilient 3D multi-layered (GSO, NGSO, HAPS, drones) network architecture. - a software defined payload adapted to all flying platforms and all frequency bands - a very low Earth orbiting space segment - a flexible waveform supporting terrestrial and non-terrestrial deployments. - the support of smart phones and vehicle/drone mounted terminals - the use of new spectrum (i.e. C and Q/V bands) in coexistence with the terrestrial network component - high accuracy and reliable positioning solutions. The newly designed NTN component will deliver: i.e. uRLLC (latency < 10 ms) and advanced eMBB (data rate up to several hundred of Mbps) services to vehicle, drone mounted ultra-small size devices, and battery activated nomadic terminals; ii. improved eMBB services to smartphones; iii. short emergency messaging services to smartphones in light indoor/in-vehicle environments; and iv. high accuracy (<10 cm) and reliable location service to both devices categories. By pulling together leading players across all involved industrial, research and innovation areas, the 6G-NTN ambition is to become the flagship R&I project to define the 6G NTN component and to drive its standardization in 3GPP.

Keywords: 6g,ntn,vleo,satcom,multilayered architectures,standardization
Biosensor-Based Diagnostic Platform Enabling Real-Time Monitoring of Existing and Emerging Pollutants (BIOSENSEI)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Clean Environment and zero pollution
Action type: Research and Innovation actions
Countries involved: Ireland,Netherlands,France,Spain,Switzerland
Call: Biosensors and user-friendly diagnostic tools for environmental services (HORIZON-CL6-2023-ZEROPOLLUTION-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 3998191.99
EU funding (EUR): 3998191.49
Participants: 9
Project status: SIGNED

BIOSENSEI develops a real-time, multiplexed, end-to-end, tailored and reliable biosensor platform, using cellular responses, for detection of abiotic pollutants - Nutrients, Estrogenic endocrine-disrupting chemicals, and PFAS (Perfluoroalkyl and Polyfluoroalkyl Substances); and biotic pollutants - Microcystins. Cellular biosensors from bacterial variants will be genetically engineered using, RNA-RNA interactive and type III CRISPR-Cas-mediated transduction cascades. These biosensors are encapsulated and immobilised at bi-modal transducers (nanoelectrochemical and optical) to provide highly reliable, tuneable and sensitive detection of the target pollutants. Bespoke ultra-low power analog front ends and autonomous IoT end-nodes will enable operation and data acquisition from biosensors and facilitate easy integration in existing LoRa networks enabling real-time data feeds. Neural computing algorithms are embedded on the edge to correct for sensor aging and interferents in the (bio)chemical transduction and improve sensor data accuracy. An online dashboard will be developed to allow end users to visualize data. BIOSENSEI will embed the whole R&D process within a safe-and-sustainable-by-design framework to guarantee environmental safety related to risks of potential release into the open environment. Biosensors will be scalable, adaptable to different applications in water & soil and will be deployed in four different use-cases. The consortium is vertically integrated bringing expertise in cellular biology, surface chemistry, nanoelectronics fabrication, hardware integration, regulatory and industrial sampling and artificial intelligence. BIOSENSEI directly addresses HORIZON-CL6-2023-ZEROPOLLUTION-01-6 Biosensors and user-friendly diagnostic tools for environmental services and will allow cellular biosensors to be deployed outside laboratory settings for the first time the project and has the potential to considerably contribute to fulfil EU vision on zero-pollution.

Keywords: whole cell biosensors,pollutants,optical and electrochemical transducers,iot,artificial intelligence
Quantum INteracting Topological Optics (QUINTO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-06-01
End date: 2026-05-31
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: SIGNED

Atom-light interfaces are vital for a range of potential applications in the coming “second quantum revolution”, from secure communication to ultra-precise sensors to quantum computers. A new exciting possibility is to arrange atoms in dense, regular arrays, where wave interference leads to strong collective emission. This property has been shown to polynomially or even exponentially improve the efficiency of single-photon-level applications. A frontier still awaiting a breakthrough is in the many-body regime, in particular, to expand the realm of atom arrays interacting with light toward realizing and studying exotic strongly correlated behavior. In QUINTO (Quantum INteracting Topological Optics), we will propose routes by which such systems can realize many-body states featuring topological order (TO). TOs have attracted significant interest due to wide-ranging implications ranging from possible fault-tolerant quantum computing to surprising fundamental properties such as the emergence of “anyonic quasi-particles” (being neither bosons nor fermions) and emergent lattice gauge theories. We will use the known physics of TOs within condensed matter physics as a “window” to developing the concept of many-body quantum optics, and show that, in turn, the arrays provide new ways of creating, understanding and measuring TOs. We will employ innovative, condensed-matter-inspired theoretical and numerical techniques, breaking state-of-the-art limitations (e. g. on system size), to study two routes towards quantum-optical TOs: arrays in optical cavities and “topological bands” in free-space arrays. We aim to: (i) demonstrate that long-range interactions, induced by emission and re-absorption of photons, provides a new paradigm for inducing TOs, (ii) elucidate the influence of such interactions on fundamental TO physics, and (iii) show that the output light carries information sufficient to detect a TO (including signatures of anyons).

Keywords: quantum optics with atom arrays,cavity qed,subradiance,spin liquid
Well-Defined Silica-Supported Titanium Catalysts for Introducing Nitrogen Functional Groups (SiTi-CAT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France,Canada
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-11-14
End date: 2025-11-13
Duration (months): 36.0
Total project cost (EUR): 291785.28
EU funding (EUR): 291785.28
Participants: 2
Project status: CLOSED

Amines are commercially valuable compounds used in a wide range of products including pharmaceuticals, agrochemicals and polymers (global market USD 16.6 billion), but their industrial synthesis is inefficient and expensive. Alternatively, nitrogen functional groups can be synthesised by green, 100% atom efficient reactions (hydroamination and hydroaminoalkylation) that are catalysed by earth-abundant homogeneous Ti complexes. These reactions are not yet industrially viable due to high costs of catalyst recovery and product purification. We need to develop catalysts for these processes that exhibit the high activity and selectivity of homogeneous Ti catalysts but are industrially viable. This project will develop new heterogeneous catalysts for introducing nitrogen functional groups by immobilising Ti complexes based on homogeneous catalysts for hydroamination and hydroaminoalkylation onto silica surfaces. It will blend the disciplines of chemical synthesis, homogeneous catalysis, and surface organometallic chemistry by using the expertise of researchers and specialist facilities in Canada and France. I will: synthesise novel catalysts featuring well-defined Ti metal centres supported by ligands immobilised on silica surfaces, optimise their activity for hydroamination and hydroaminoalkylation on industrially important substrates, and investigate the mechanism of the reactions to optimise and enhance industrial applicability. This project will transform green processes to manufacture nitrogen-containing chemicals from academic research into industrial routes. Knowledge and key skills in chemical synthesis, catalyst development and surface organometallic chemistry will be shared between European and Canadian researchers, resulting in a synergic partnership impacting academic and industrial fields. I will apply my previous experience and learn new technical and transferable skills, which will advance me to my goal of becoming an independent academic researcher.

Keywords: surface organometallic chemistry,green chemistry
Hybrid polymer nanoparticles as gene vectors (HyPlex)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Ireland
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 215534.4
EU funding (EUR): 215534.4
Participants: 1
Project status: SIGNED

Gene therapy has long been seen as a promising solution to unmet clinical needs and the licencing of gene therapy SARS-CoV-2 vaccines has provided a flavour of the technology’s potential. However, gene therapy still faces significant challenges in clinical and commercial translation including the need for effective and safe delivery vectors. Polymeric nanoparticles offer great flexibility in gene vectors design, improved stability and easier scale-up of production compared to lipid nanoparticles but often suffer from cytotoxicity and underperformance in vivo. The goal of HyPlex is to develop the next generation polymeric nanovectors which can easily be functionalised to further improve delivery efficacy. The project will develop novel chemistry to achieve polylysine/polyacrylate hybrid nanogels. Functionalisation of nanogels will be demonstrated by the introduction of mannose, a common cell binding motive as well as diethylene glycol ethyl ether arylate to optimise the hydrophilic/hydrophobic balance. In an interdisciplinary approach gene loading and cell transfection will be studied up to in vitro level. The project results will be exploited as part of an ongoing commercialisation initiative at RCSI, which will provide the applicant with a unique experience in research translation and commercialisation. The high-level science is complemented by bespoke training activities, which will significantly advance the career opportunities of the applicant. Project results will be communicated to peers as well as the public with specific focus on encouraging female secondary school pupils to take up scientific careers.

Keywords: nanogels,polypeptides,polyacrylates,gene delivery,soft nanomaterials
Clinical validation of GLIX1: a small molecule that targets epigenetic changes in cancer cells to treat glioblastoma multiforme (GBM), the highest global unmet need in oncology. (CureGLIO)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Norway
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 19356125.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Glioblastoma Multiform (GBM) patients usually die 12-18 months after diagnosis, with a 5-year survival rate of 6.8%. There are only 5 therapies approved to treat GBM and all of them provide marginal improvements of <9 months to patients’ survival. With a clinical pipeline that is constantly failing (last approval in 2004) and the lack of effective therapies, GBM remains the highest unmet need in oncology. After years of research, we discovered the GLIX family, which targets a newly discovered mechanism that is deregulated in cancer cells. GLIX1 was more effective than the current standard of care at killing several GBM cell lines. In vivo studies showed tumour regression in 100% of mice, with a tumour growth inhibition of 94%. With such promising results and an experienced team, GLIX1 is now ready for clinical validation. The support from the EIC will help us to prove the clinical safety and efficacy of GLIX1 and make it globally available through licensing to a large pharma company.

Keywords: brain cancer,rare disease,orphan drug,clinical validation,glioblastoma,epigenetics
Understanding the Consequences of Major Health Crises for Education: Learning from the COVID-19 Pandemic (LEARN) (LEARN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 1499853.0
EU funding (EUR): 1499853.0
Participants: 1
Project status: SIGNED

Health crises, natural disasters, and violent conflicts pose global threats to children’s educational development. The frequency and severity of such disruptive events is intensifying due to climate change and the growing instability of the global security architecture. Yet, we lack a systematic understanding of how major disruptive events affect children’s educational development, largely because such events tend to also disrupt the collection of high-quality data on children’s education. Due to the global scale of the COVID-19 pandemic and extensive data collection efforts as it unfolded, the COVID-19 pandemic offers a unique opportunity to advance our understanding of the consequences of major health crises for children’s educational development. LEARN will leverage this opportunity to reveal the principal pathways through which the pandemic has affected the educational development of children in different world regions, as well as the key factors that reduce or exacerbate its adverse consequences. LEARN will generate and apply high-quality, cross-national data and advanced quantitative and meta-analytical techniques to achieve five core objectives: (1) Trace children’s recovery of COVID-19 learning deficits using a living meta-dataset and online tracker (2) Assess COVID-19 effects on children’s early-life trajectories (3) Map the processes through which the pandemic affected children’s educational development (4) Reveal the factors that reduce or exacerbate COVID-19 effects (5) Identify the most effective remedial education interventions to promote children’s learning recovery This ambitious and innovative research programme will substantially advance our understanding of how major health crises affect children’s educational development, generate several new data resources, and provide a basis for policy makers to future-proof education systems to meet the growing threats posed by major disruptive events.

Keywords: covid 19 pandemic,health crises,educational development,educational inequality
A Multidimensional Analysis of Racism and Social Immobility at the Societal Level (MARIS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Belgium
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-05-01
End date: 2030-04-30
Duration (months): 60.0
Total project cost (EUR): 1968787.5
EU funding (EUR): 1968787.5
Participants: 1
Project status: SIGNED

Two of the most profound sources of exclusion in current-day societies are people’s ethnic and social origins. The main goal of MARIS is to examine the interlinked patterns of different dimensions of racism and intergenerational social immobility at the level of societies. Racism refers to the historically grown beliefs and practices that systematically disadvantage some ethno-racial groups. It has been conceptualized and measured by different research traditions, which each focuses on another aspect of racism. Intergenerational social immobility refers to the transmission of parents’ socioeconomic positions to those of their children. Also here, there are different traditions to examine these positions. What both racism and social mobility research have in common, is that there is little interdisciplinary integration of their dimensions. This is a serious gap, because each approach only covers a specific aspect and often yields different answers to basic research questions. Therefore, MARIS starts with a theoretical and empirical integration of four dimensions of racism at the macro-level: discriminatory behaviour, perceived discrimination, explicit attitudes and implicit bias. The macro-approach will consolidate the recent macro-social turn in racism research and opens a new paradigm of research questions. In the same vein, I also integrate four dimensions of social mobility: social class, status, income and education. In the next step, MARIS examines the interlinked patterns of racism and social mobility at the macro-level. While racism and immobility are intertwined in people’s lives and I can theoretically expect four possible combinations of both sources of exclusion, previous studies tend to examine them separately. By combining both, this project bridges two long-standing research fields within the social and economic sciences. Lastly, I analyse varying levels in racism and mobility across countries and time by their links with macro-policies and recessions.

Keywords: discrimination implicit bias prejudices intergenerational social mobility social class income education
Climate just housing: Towards more sustainable urban environments for all (CLIMATEJUSTHOME)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-01-15
End date: 2025-01-14
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 3
Project status: CLOSED

Climate change is profoundly impacting cities and their inhabitants, leading to increased infrastructure failure, food and resource shortages and death. Research has shown that vulnerable households are not only the most exposed to these effects, but also experience displacement when cities implement green, climate-adaptive interventions that change housing markets and their affordability. In Europe, the carbon neutrality goals set by the European Green Deal will trigger unprecedented transformations that might exacerbate these vulnerabilities. In a context where new climate-adapted housing is reaching largely middle- and high-income groups, more research is needed to understand how housing access can be ensured for all residents in green, climate adapted cities. CLIMATEJUSTHOME fills this gap through an innovative mixed methods approach that builds from an in-depth understanding of vulnerable households’ lived experiences and the unique insights they offer to advance just urban climate adaptation, housing planning and policy-making. Using a case study strategy focusing on Spain’s greenest city Vitoria-Gasteiz, I will deploy policy analysis, spatial analysis, ethnography and ethno-spatial mapping workshops to generate data housing and climate (in)justices towards building new theory and knowledge on climate just housing. With the support of my supervisor (Prof Lancione) and his cutting-edge European Research Council (ERC) Beyond Inhabitation Lab at the Politecnico di Torino, as well as the award-winning Basque Centre for Climate Change BC3, the Fellowship will train me in ethnography, intersectional analysis and ethno-spatial mapping and act as a pilot for my own ERC Starting Grant on climate just housing. Ultimately, the project seeks to expand theoretical and practical knowledge about how cities embracing climate change adaptation strategies can develop just housing and urban interventions towards carbon neutrality.

Keywords: urban climate change adaptation,housing struggle,intersectionality,eviction,displacement