Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A lightweight, fast charging, EV platform to be utilised on Car Share and Urban Mobility Systems (NedraEV)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: United Kingdom
Call: Small business innovation research for Transport (H2020-SMEINST-1-2015, 2015)
Start date: 2016-04-01
End date: 2016-08-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The concept is to create a family of novel, lightweight EVs, through an EU based organisation co-ordinating design, manufacture, supply and support service infrastructure, targeted at producing zero emission city mobility for co-ordinated hire schemes, transportation networks, taxi or private individual transport. EC policy demands sustainable urban mobility, specifically within the growing carshare and city hire market. Nedra has been formed specifically to capitalise on these emerging opportunities through an Electric Vehicle (EV) platform where Product Specification and New Product Development processes are optimised to match exactly the market needs and the mantra “just enough” is applied. The Nedra product range features a combination of lightweight, low cost, longer range and rapid charge platform that is not currently met by any single existing product. This will be key to realising the company’s growth strategy of sales turnover of €36milion p.a. by 2020. In addition to the product range we have identified that, we can create an EU-based network which co-ordinates manufacture, supply and service for this family of EVs worldwide. The purpose of this feasibility study is to confirm some of the assumptions regarding the market, identify further key suppliers and partners, and establish the product legislative and compliance needs.

Keywords: electric vehicle,lightweight,fast charge,high performance,efficient transport,low cost,zero emissions
Support to the SciPost initiative (2020-2021) (ERC-SciPost-2019)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Low value grant
Action type: ERC actions
Countries involved: Netherlands
Call: Support to the SciPost initiative (H2020-IBA-ERC-SCIPOST-2019, 2019)
Start date: 2020-05-01
End date: 2022-04-30
Duration (months): 24.0
Total project cost (EUR): 60000.0
EU funding (EUR): 60000.0
Participants: 1
Project status: CLOSED

This project will enable SciPost to enhance its metadata handling facilities. In accordance with the goals stated in the Work Programme, we hope to develop the "backend" of our metadata-related publishing services, enabling us by extension to offer new tools for different classes of academic users. Overall objective: To enhance our already industry-leading extended metadata handling facilities for all facets of our scientific publishing activities, to extend their content coverage, and to enlarge their user base by providing tools targeted at authors, funders and the broader community. Specific objectives: • To enhance our existing metadata schema and handling infrastructure for researcher profiles, publications, organizations and funder-related data (funder instances, grant instruments, funding rounds, grant instances); • To widen the coverage of this data, and make it as universal as possible; • To interlink this data and provide open online facilities for using it, thereby creating a set of useful tools for the community (curated researcher disambiguator; publication listing; affiliations; coauthorships/conflict of interest checker; referee finder; grant reporting); • To promote these tools as useful additions to scientific and administrative workflows in general, and facilitate the implementation of our business model in particular.

Keywords: open access publishing,metadata,publishing business models
Commercialisation of Advanced Extrusion Technologies Delivering Disruptive Innovation for the Next Generation of Catheter Based Medical Devices. (ExtruLub)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Ireland
Call: Accelerating the uptake of nanotechnologies, advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2015, 2015)
Start date: 2015-07-01
End date: 2015-11-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

ExtruLub is an innovative, disruptive extrusion technology applicable across a range of medical polymer resins, which has the ability to change the surface of a catheter without affecting core device properties. The technology sits in the component sub-supply global market with an initial value of €564mn applicable across all catheter markets (combined value of $42.5bn globally by 2020). From a functional perspective, ExtruLub has the ability to reduce surface friction, generate protective antimicrobial & anti-thrombogenic surfaces & deliver site specific drugs all whilst reducing catheter profile. This enhancement of catheter function assists in safeguarding patient safety & will command genuine product differentiation for the original equipment manufacturer (OEM) of the end device, enabling them to gain market share.From an economic perspective it facilitates a change from lean to batch manufacturing realising cost containment for the target customer.Taking the cardiology sector as an example, an independent study demonstrated ExtruLub would reduce costs for the OEM (eg Boston Scientific, Medtronic etc.) by 51% realising savings of ca. €3mn p.a in one product. In the urology sector, the measured impact showed increased gross margins of ca.13% on one product line alone enabling €21.5 mn p.a. savings for potential customers like Hollister, Coloplast etc. DiaNia Technologies ambition is to grow into a world leading, international technology company, realising market share through disruptive technologies.Our initial goal is to replace current ExtruLub alternatives attaining a 30% market share with the friction product, equating to €170mn in full production.Harnessing advanced polymer chemistry through materials science and engineering has the potential to realise €23.3mn in revenue & 15 new, highly skilled jobs within the first 4 years through a business model preferred by OEMs.This disruptive technology is the key to advancing the next generation of medical devices.

Keywords: medical device coatings,extrulub technology,inbuilt surface modification,disposable catheter market,antimicrobial catheter,medical devices dehp plasticised pvc,www zeusinc com ptfe
Contact lens embedded sensor for ocular hypertension and glaucoma monitoring (Savesight)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Türkiye
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2020-01-01
End date: 2020-06-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Glaucoma affects over 70 million people worldwide (>12 million in Europe), and this number is expected to grow steadily to reach 111 million by 2040. Glaucoma is a chronic condition with no permanent cure and is the second leading cause of blindness. It significantly reduces the quality of life and presents a heavy burden on healthcare systems. Its most prominent and stealthy form, namely open-angle glaucoma, is mainly caused by chronic ocular hypertension (high intraocular pressure [IOP]). Conventional methods used to diagnose elevated IOP, monitor the progression of glaucoma and create treatment algorithms rely on a single IOP measurement conducted at the clinic. Due to the diurnal cycle of IOP, conventional methods do not provide sufficient and reliable information to evaluate the condition of the patients accurately. GlakoLens has been developing a non-invasive contact lens embedded sensor system that will aid medical professionals to overcome this issue by continuous 24-hour monitorization of the IOP changes. GlakoLens' proprietary technology (1 granted and 3 pending international patents) based on years of cutting-edge scientific research enables superior features for the patient (better comfort, electrical and mechanical safety, and full field-of-view) at a fraction of the cost of the only direct competitor in the market while providing better measurement accuracy and reliability. Four more indirect competitors have recognised the need in the market and are developing products using different technologies to address this need. According to a report by Marketscope, IOP monitoring market is expected to reach €1.5 billion by 2021. Glakolens plans to enter the market by the end of 2022, with estimated revenues equal to about €294.6 million in 2026.

Keywords: digital health,biosensor,medical device,intraocular pressure measurement,glaucoma,ocular hypertension,personalized health
Extending fresh food shelf-life through novel plant-derived biofungicides for post-harvest treatments (AgroShelf)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Today up to a third of all food produced—and almost the 50% of fruits and vegetables (F&V)—perishes before being used with a consequent economic and environmental cost of $1.7 trillion. Somewhere between the 20% and 40% of F&V are lost at postharvest stages, during handling, storage and distribution. Among causes, food spoilage due to fungal pathogens such as molds leads to substantial food waste and an estimated $100 billion of economic losses for producers, retailers and consumers. Traditional control of fungal infection relies on preharvest (field) application of synthetic fungicides, but their use is being progressively banned and efficient natural alternatives are lacking on the market. Moving from this scenario, AgroSustain has identified and patented more than 60 antifungal plant-derived compounds, getting to the formula of a new generation of highly-efficient and cost-effective natural fungicides. Our first product, AgroShelf+, shows an unprecedented fungitoxic efficacy against a wide range of mainly spread fungi, thus preventing postharvest fruit spoilage and extending the F&V shelf-life by a minimum of 7 days. This will allow food retailers and distributors using AgroShelf+ to greatly reduce their food loss costs and improving food quality for consumers. Starting with Switzerland in 2020, AgroSustain plans to expand sales to other EU countries (France, UK and Germany). During this Ph1 project we will optimize the product formulation in order to stress the AgroShelf+ performances targeting specific crops. We will also go through the first round of toxicity tests requested for the certification and regulative approval pathway. A cost-benefit analysis and a deeper market research will also consolidate our pricing strategy and business model. This will pave the way for the pilot test with large retailers in the Phase 2 project.

Keywords: food waste,shel life extension,fruit and vegetable spoilage,natural fungicides
Solid Immersion Lens Microscopy to Study Cilia Assembly (SILIA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Czechia
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-04
End date: 2021-12-21
Duration (months): 24.0
Total project cost (EUR): 156980.64
EU funding (EUR): 156980.64
Participants: 1
Project status: CLOSED

Cilia and flagella are evolutionary conserved organelles indispensable for vital processes in eukaryotic organisms, such as environment sensing, cell motility, signaling and development. Broad spectrum of ciliary functions, together with omnipresence of the cilium throughout human body, explains the range of symptoms associated with congenital ciliary disorders called ciliopathies. On the other hand, cilia are essential for survival of parasites, such as trypanosomatids, in the host. Therefore, cilia are of great interest as a potential therapeutic target. The ciliary tip is an essential ciliary domain; it provides capping and mechanical stabilization of the ciliary cytoskeleton, it is a turning point of the intraflagellar transport trains, a sole place of cilium growth and a place of budding of signaling vesicles. Yet the tip is the most enigmatic of all ciliary domains, with structures constituting the ciliary tip largely unknown. This hampers our understanding of how are the tip-related processes brought about and orchestrated. To gain insight into the dynamic ultrastructure od the ciliary tip, I will develop a novel technique for cryogenic correlative light and electron microscopy based on solid immersion lens (SIL) optics. I will integrate the resulting imaging data with the tip proteome project project carried out by the host lab and provide mechanistic understanding of the resulting tip model by employing top-down synthetic biology and in vitro reconstitution approaches. Key achievements of this project will include: (i) development of the cryo-SIL technique and (ii) unraveling the functions of the the ciliary tip domain, which will broaden our knowledge of the principles of self-organization of biological systems.

Keywords: cilia,flagella,axoneme,microscopy
In-time TReatment of acUte ischaemic STroke (iTrust)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Denmark
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-05-01
End date: 2021-10-31
Duration (months): 30.0
Total project cost (EUR): 2616250.0
EU funding (EUR): 1831375.0
Participants: 1
Project status: CLOSED

The problem: Today the complex and time-critical therapeutic decision in Acute Ischaemic Stroke (AIS) relies on the availability of expert stroke radiologists. However, only 5% of hospitals have facilities meeting the standards of comprehensive stroke centres. Thus, for 95% of hospitals, optimal treatment cannot be quickly identified and safely commenced. Consequently, only about 30% of AIS patients receive specialized stroke unit care across Europe. The solution: iTrust is a clinical decision support (CDS) software that uses Convolutional Neural Networks to predict the outcome of treatment strategies in AIS, based on the patient’s biomarkers as well as clinical information, including brain scan images. The prediction shown as high-resolution images of probable brain tissue outcomes in function of each treatment available. The market: Revenue from the iTrust software will come as annual licences fees: a model clearly preferred according to the surveyed KOLs. Initially, the distribution of the software will be carried out through strategic partnerships (formal agreements already signed) with the major medical scanner (CT, MRI) vendors, which will allow us to exploit their global sale channels and large installed base. The total addresable market for iTrust is over EUR 430 million per year in OECD countries. Given the high incidence of AIS, low volume (5%) of hospitals prepared to initiate the treatment and the high importance of quickly allocating the appropriate therapeutic intervention, we estimate an accumulated turnover exceeding EUR 41 million of the iTrust solution, five years post-project.

Keywords: acute ischaemic stroke,clinical decision support software,treatment decision
Moduli, Algebraic Cycles, and Invariants (MACI)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2017-ADG, 2017)
Start date: 2018-09-01
End date: 2023-08-31
Duration (months): 60.0
Total project cost (EUR): 2496055.0
EU funding (EUR): 2496055.0
Participants: 1
Project status: SIGNED

Algebraic geometry is the study of varieties -- the zero sets of polynomial equations in several variables. The subject has a central role in mathematics with connections to number theory, representation theory, and topology. Moduli questions in algebraic geometry concern the behavior of varieties as the coefficients of the defining polynomials vary. At the end of the 20th century, several basic links between the algebraic geometry of moduli spaces and path integrals in quantum field theory were made. The virtual fundamental class plays an essential role in these connections. I propose to study the algebraic cycle theory of basic moduli spaces. The guiding questions are: What are the most important cycles? What is the structure of the algebra of cycles? How can the classes of geometric loci be expressed? The virtual fundamental class and the associated invariants often control the answers. A combination of virtual localization, degeneration, and R-matrix methods together with new ideas from log geometry will be used in the study. Most of the basic moduli spaces in algebraic geometry related to varieties of dimension at most 3 -- including the moduli of curves, the moduli of maps, the moduli of surfaces, and the moduli of sheaves on 3-folds -- will be considered. The current state of the study of the algebraic cycle theory in these cases varies from rather advanced (for the moduli of curves) to much less so (for the moduli of surfaces). There is a range of rich open questions which I will attack: Pixton's conjectures for the moduli of curves, the structure of the ring of Noether-Lefschetz loci for the moduli of K3 surfaces, the holomorphic anomaly equation in Gromov-Witten theory, and conjectures governing descendents for the moduli of sheaves. The dimension 3 restriction is often necessary for a good deformation theory and the existence of a virtual fundamental class.

Keywords: moduli spaces,curves,sheaves,surfaces,gromov witten,tautological classes,donaldson thomas,givental teleman
Water column profiler for quantification of photosynthesis and biomass of phytoplankton in natural and man made water bodies (Watecco)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Israel
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2014-11-01
End date: 2016-04-30
Duration (months): 18.0
Total project cost (EUR): 149775.0
EU funding (EUR): 149775.0
Participants: 1
Project status: CLOSED

Watecco is a unique, photoacoustics based profiler, designed to determine the depth distribution of natural phytoplankton assemblages and of algal cells in mass cultures and of their photosynthetic efficiency. It can report the stratification of the light absorbing photosynthetic pigments and is unique in its sensitivity to document changes in the quantum yield of phototrophic plankters. The profiler is of great importance in following the health and photosynthetic light utilization efficiency of natural and manmade water bodies, freshwater and marine. Since increase in photosynthetic efficiency and the related proliferation of algal biomass of phytoplankton in lakes, rivers and in the sea occurs mainly as a result of nutrient enrichment, or anthropogenic eutrophication, as well as due to Global Climate Change related water acidification, Watecco can provide an early warning alert call to environmental pollution by urban or farm sewage, compromising the safety of water supplies and coastal fisheries. Furthermore, the capability of Watecco to provide fast, real time data on the efficiency of photobioreactors and algal mass cultures makes it a unique tool in the optimization of these devices for attaining high yields of their target products. Commercialization activities of Watecco include market analysis, financial and business planning, legal workup, IPR protection and contracting with manufacturers and investors. The project also covers the finalization of the development of a submersible prototype, a user friendly interface, and its field testing and data validation. This innovative technology will yield reliable and robust data for coastal authorities responsible for evaluation of the proliferation and collapse of algal populations, marine labs and nature reserves, water supply authorities, industries involved in the mass culture of algae for the production of biodiesel and fine chemicals, and installations based on high-rate-algal sewage treatment systems.

Keywords: water quality,drinking water,water warming and acidification,biomass,quantum yield of photosynhtesis,profiler,biofuel
ENVISAGE (Development of Environmentally-friendly Innovative Solutions for Affected Grounds and Ecosystems) (Envisage)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Germany
Call: European SME innovation Associate - pilot (H2020-INNOSUP-02-2016, 2016)
Start date: 2017-09-01
End date: 2018-08-31
Duration (months): 12.0
Total project cost (EUR): 91250.0
EU funding (EUR): 91250.0
Participants: 1
Project status: CLOSED

In line with our growth strategy, INOQ is looking for an innovation associate to lead our business expansion project into the soil remediation market in Europe. With more than 20 years of experience, our company INOQ is a leading developer of mycorrhiza products used as microbial biostimulants for reforestation, food production, horticulture and others. With ENVISAGE we will provide mycorrhizal fungi to soil remediation companies as a complement and/or alternative to current remediation techniques for contaminated or affected grounds During the last decades, governments and private institutions have stressed their interest towards substitution of ecologically unfriendly and expensive remediation techniques with new forms of bioremediation. Given its relevance to our life, the governments and private actors from the EU member states have incurred in large amounts of soil remediation related expenses during the last years (more than €31 Billion from 2000 to 2010). To date there are many laboratory applications of mycorrhizal fungi on soil remediation, but no commercial applications in Europe. Therefore we identify our competitive advantage given our technical and commercial experience with similar applications. Based on our preliminary market analysis and based on advisory from industry experts, this market would represent for INOQ a business with an annual revenue value of at least €5 Million during the first 3 to 5 years. The envisaged profile has been considered to combine complementary skills and expertise. The innovation associate will use her/his research and qualitative/quantitative data analysis skills, as well as her/his bioscience and technical background to connect the market and industry related knowledge to our biotechnology. The incumbent will have a strategic role in INOQ, occupying the position of Business Innovation Manager. She/He will contribute to drive our company to become a reliable biotechnological partner in European soil remediation market.

Keywords: mycorrhiza fungi,microbial biostimulants,soil remediation,polluted grounds