Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Glaucoma – Advanced, LAbel-free High resolution Automated OCT Diagnostics (GALAHAD)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Partnership: Photonics (cPPP)
Countries involved: Germany,Spain,Denmark,Denmark,United Kingdom,United Kingdom,United Kingdom
Call: Photonics KET 2016 (H2020-ICT-2016-1, 2016)
Start date: 2016-12-01
End date: 2019-11-30
Duration (months): 36.0
Total project cost (EUR): 3996783.75
EU funding (EUR): 3996780.0
Participants: 10
Project status: CLOSED

The project GALAHAD targets the critical need for better glaucoma diagnostic systems. Glaucoma is an age-related major cause of blindness. The eye disease is characterized by an irreversible damage to the optic nerve head caused by increased intra-ocular pressure. The current screening and basic diagnostics for the disease involve intra-ocular pressure measurement, visual field tests and detection of structural damage to the optic nerve head and retinal nerve fibre layer. The present methods have high rates of false positive or false negative results since the in depth analysis of optical nerve head damage is not possible due to the poor resolution of available optical technologies. A leading candidate is optical coherence tomography (OCT), but the required axial resolution is ~1 μm, well beyond the 3-5 μm resolution of commercial systems. GALAHAD aims to develop a label free, compact and easy to operate high resolution diagnostic OCT system. The multiband and multimodal system will use submicron ultra-high resolution polarisation sensitive OCT (UHR PS OCT). The key breakthrough elements are: (i) A revolutionary low cost multiband supercontinuum light source. (ii.) Ground-breaking ultra-broadband photonic components required to exploit such a source. (iii.) Automated glaucoma screening algorithms: using end user evaluation of cell and animal models and tissue samples, automated algorithms will be developed, trained and tested so that non-expert operators will be able to perform glaucoma screening. The GALAHAD in depth glaucoma diagnostics after a positive screening with conventional methods will dramatically reduce false positive and false negative screening results and decrease the number of patients suffering from glaucoma-related disability. The project is driven by world leading companies and manufacturers of OCT systems and guided by requirement specifications and validated by high ranking clinical and experimental ophthalmologists in their clinical settings.

Keywords: glaucoma,ultra high resolution,polarisation sensitive,optical coherence tomography,supercontinuum,spectrometer
Platform Discourses: A Critical Humanities Approach to the Texts, Images, and Moving Images Produced by Tech Companies (PLATFORM DISCOURSES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Netherlands,Netherlands
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2019-12-01
End date: 2024-11-30
Duration (months): 60.0
Total project cost (EUR): 1223750.0
EU funding (EUR): 265000.0
Participants: 2
Project status: SIGNED

This project aims to develop a critical humanities perspective on the platform society, in which the online platforms owned by major tech companies—from Google to Facebook, from Apple to Airbnb—are integrated into all domains of life. In recent years, scholars across the humanities and the social sciences have analysed the functioning of platforms and their social impact. However, there has not yet been a systematic scholarly analysis of the discourses through which tech companies seek to generate trust around their products, addressing people not only as consumers, but increasingly also as a general “public.” This angle is crucial, because tech discourses are not mere by-products of platforms themselves, but form an integrated part of the development in which tech companies present their market-driven services as neutral spaces for social interaction. Platform Discourses offers this angle on tech companies as discourse producers by employing methods of narrative, image, and discourse analysis in order to analyse the texts, images, and moving images generated by tech companies: from books to corporate blogs (e.g., Airbnb’s Citizen blog), from product presentations to billboard campaigns (e.g., Apple’s World Gallery), from manifestos to public statements (e.g., Microsoft’s call for a digital Geneva convention). The project identifies the ideological underpinnings of those materials. What are the dominant visions of individual and collective human existence tech companies develop in their discourses? How have these visions evolved over the decades? And what conceptual understandings of humanity inspire Google’s mission to “do no evil” or Facebook’s ideal of a “global community”? Answering these questions, Platform Discourses presents a critical framework to understand how tech companies not only disrupt traditional markets and transform people’s practices, but also seek to reconfigure the stories through which people relate to themselves, others, and their ecosystems.

Keywords: platform society,online platforms,theories of everyday life,attention and attention studies,critiques of humanism,critical humanities,narrative analysis,image analysis,moving image analysis,digital age
Living on the Edge: Tunable Electronics from Edge Structures in 1D Layered Materials (TESLA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-01-01
End date: 2024-06-30
Duration (months): 66.0
Total project cost (EUR): 1499475.0
EU funding (EUR): 1499475.0
Participants: 1
Project status: SIGNED

One of the driving forces of the ongoing nanotechnology revolution is the ever-improving ability to understand and control the properties of quantum matter even down to the atomic scale. Key drivers of this revolution are layered materials like transition metal dichalcogenides (TMD). The realisation of novel TMD-based electronic devices relies heavily on understanding the relation between structural and electrical properties at the nanoscale. Crucially, one-dimensional (1D) TMDs have been predicted to exhibit striking functionalities including metallic edge states, ferromagnetic behaviour, and mobilities that are not suppressed as compared to their 2D counterparts. Indeed, in the 1D nanoscale limit, the lateral edges of TMDs become dominant, opening novel opportunities to tune edge-induced electrical properties leading to i.e. enhanced charge carrier mobility. However, these predictions for novel phenomena in 1D TMDs lack experimental verification, due to the challenge in accessing the relevant information at the nanoscale. I propose to unravel the interplay between structural and electrical edge-induced properties by exploiting recent breakthroughs in electron microscopy (EM) allowing simultaneous unprecedented spatial and spectral resolution. I will focus on MoS2 nanoribbons, and use electron-energy loss spectroscopy to map the electronic properties at the nanometer-scale. Beyond the optimization of EM for 1D TMD characterization, I will investigate semiconducting-to-metal and ferromagnetic transitions by realising controllable edge structures. I have an extensive track record in pushing the frontier of EM characterization and growing nanostructures. I recently demonstrated the feasibility of pinning down the interplay between structure and electronic properties at the edges of 2D MoS2. This proposal will provide input towards novel quantum technologies for developing low-energy-consumption tunable electronics, efficient signal processing and quantum computation.
Cultural production, social movements and virtuous spirals; Using cultural production to influence social transformation. An ethnographic case study of a transmedia and translocal experiment. (IMAGINACTIVISM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United States,United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-12-01
End date: 2018-11-30
Duration (months): 36.0
Total project cost (EUR): 251857.8
EU funding (EUR): 251857.8
Participants: 2
Project status: CLOSED

In this action I will track the people and processes involved in adapting the novel The Fifth Sacred Thing as a transmedia phenomenon, whose stated goal is: “to help nurture and support the movements that are already growing to put our world on a path of peace, justice and ecological harmony”. I will focus on the producers’ intentions to “be faithful to the book’s artistic vision … but also … to the values of earth-care and social justice the book represents”. I will explore the ways that they work to “set new standards for environmental accountability in the film industry … bring resources into the inner city by networking with community organizations … put up a website with extensive resources and develop many ways that the people who are inspired by the vision can learn the skills they need to create it and connect with others who share it.” Together, the book’s artistic vision and the producers’ plans provide a rich case study in inventive approaches to creating, inclusive, innovative and secure societies. I will use this empirical case study to develop and test the concept of ‘imaginactivism’ as a way of thinking through the influences fictional or artistic cultural productions exert on social and political activism, and vice versa. I will pursue research skills training in new media research and production, as well as videoethnography, so that my research methods, dissemination, and public engagement mirror and extend the phenomenon I am investigating. This will enable me to meet the objectives of: producing articles and a monograph about the transmedia phenomenon of The Fifth Sacred Thing; articulating the methods to ground conceptual work on ‘imaginactivism’ through an empirical case study; disseminating the methods to academic audiences pursuing research on cultural production and social activism; disseminating a road map for linking cultural production and social and political action to cultural producers, activists and potential activist publics.

Keywords: imaginactivism,utopian fiction,grassroots activism
Emotions as Practice in the early modern Jesuit missions in the Asia-Pacific (EMOPractices)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Australia,Italy
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2024-09-30
Duration (months): 36.0
Total project cost (EUR): 257209.92
EU funding (EUR): 257209.92
Participants: 2
Project status: SIGNED

The project “Emotions as Practice in the early modern Jesuit missions in the Asia-Pacific” (EMOPractices) approaches the XVI-XVIII-century Asian enterprises of the Society of Jesus through the lens of emotions. Introducing the concept of the “emotional Other” (the emotional dimension of the construct of the Other), it reveals the previously disregarded role of Jesuit emotional practices and their impact on the creation of stereotypes of peoples of the Asia-Pacific region. EMOPractices thus analyses the emotional typologies used by the Jesuits to classify different Asian people; it identifies the emotional practices the missionaries used to bridge cultural divides and, at the same time, establish the domination of Asian people; and it exposes the mechanisms of the discursive creation of the emotional Other, as part of the changes in early modern European understanding of the world and humankind. In this way, EMOPractices addresses the less visible historical roots of racial and ethnic stereotyping connected to discrimination, working within the H2020 Societal Challenge “Europe in a changing world.” Supported by my experience with the early modern history of the Society of Jesus in Asia and in Europe, and with their manuscript, multi-language, ethnographical literature, EMOPractices operates at the junction of history and anthropology and addresses a gap in the historiography of early modern East-West contacts. Its expected outputs consist of two journal articles, a monograph, and a website. It will also support my career, towards a tenured position at a European university, as the MSCA training will increase both my research and my transferable skills, allowing me to engage with wider areas of research and making my profile more competitive. EMOPractices will also create new networks connecting the host and secondment universities (UNIVE, ACU, Tübingen), facilitating the circulation and growth of knowledge on the history of emotions both within Europe and globally.

Keywords: early modern history,jesuit missions,catholic missions in asia,history of emotions
Multimodal glycoconjugates: a molecular Lego approach for antitumoral immunotherapy (LEGO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: France,France
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-09-01
End date: 2021-02-28
Duration (months): 66.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 4
Project status: CLOSED

Despite significant progress in cancer therapy, current treatments are still controversial due to intolerable side effects. Targeted immunotherapy has recently emerged as an ideal alternative to improve treatment modalities for cancers patients. However, very limited approaches are available today and major issues remain to be addressed. The ERC grant offers a unique opportunity to propose a new paradigm for treating cancer. Through a ground-breaking interdisciplinary program, at the crossroad of supramolecular chemistry, synthetic chemistry, molecular engineering, biophysics, biochemistry, immunochemistry and glycoscience, it is my ambition to design, synthesize and study smart biomolecular structures with unprecedented combinations, complexity and immunological properties against cancers. To achieve this purpose, I will develop a “molecular LEGO” approach to construct synthetic molecules capable of redirecting endogenous antibodies present in the human bloodstream against tumors without preliminary immunization. Efficient tumoral killing by immune effectors will be provided by molecules combining innovative antibody and tumor binding modules that will be selected in vitro beforehand. To be successful, I will address fundamental questions that are still unresolved in chemical and biological sciences. The expected breakthroughs will represent a landmark achievement in these fields and will open promising horizons in cancer immunotherapy. Beyond this, it can be expected that our findings will pave the way to future development of synthetic molecules embedded with recognition, labeling, and/or therapeutic functions. They will thus find wider medicinal, diagnostic and even theranostic applications for which the development of more effective and selective biomolecular systems is of the utmost importance.

Keywords: immunochemistry,chemical ligation,bioorganic chemistry,combinatorial chemistry,multivalency,glycoscience
Enabling mass access to the social phenomenon of e-sports tournaments by integrating In-Game Platform in world’s leading video games (Toor-IG-ICT37-2014)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: France
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2014-10-01
End date: 2015-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

A new universe of video game tournament (called e-sports) has transformed dramatically the video game industry over the last two years. However, organising and participating in e-sports tournaments remain complicated for players and publishers. OXENT wants to support and amplify this massive growth of e-sports by integrating an e-sports platform directly in top selling video games (so-called in-game approach). The current state-of-the-art reveals that no in-game tournament solution exists. With its innovation, OXENT wants to change the way video games are played, with a massive shift towards tournaments among the average player. OXENT aims to become the world leader of e-sports tournament technology with € 34 million income in 2017 and 20 employees. Our BtoBtoC solution meets the needs of both players and of publishers. Direct integration into video games democratises the use for players, by giving access to the platform automatically and intuitively. Publishers will easily shift from single sales business model to subscription. Therefore, client retention will increase, and the games life cycle will be extended. In addition, new sources of revenue will be created through tournament fees. The feasibility study will assess three key levels: 1. Technical: Test in-game performance and improve design and ergonomics. 2. Economic: Define the business model through meetings with global publishers and potential business partners 3. Legal: Identify data collection legal issues and the opportunity to protect our knowledge. For global commercialisation of our innovation, total funding requirement during 2 years for Phase 2 is estimated at € 2 800 000. The dissemination of the innovation will be global. For cultural and market size reasons, target geographies for video game players include the major European markets in France, Germany, UK and the Scandinavian countries, as well as in North America. These countries, combined, comprise 60% of the global market.

Keywords: video games,e sports,in game
IMplementation of Powertrain Control for Economic and Clean Real driving emIssion and fuel ConsUMption (IMPERIUM)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Innovation actions
Partnership: EGVI (cPPP)
Countries involved: Germany,Italy,Italy,Austria,Germany,Germany,Germany,Germany,Italy,Austria,Sweden,Switzerland,Romania,Czechia,Czechia,Netherlands,United Kingdom
Call: Powertrain control for heavy-duty vehicles with optimised emission (H2020-GV-2015, 2015)
Start date: 2016-09-01
End date: 2019-08-31
Duration (months): 36.0
Total project cost (EUR): 9915291.94
EU funding (EUR): 6625977.14
Participants: 25
Project status: CLOSED

Fuel economy is a key aspect to reduce operating costs and improve efficiency of freight traffic, thus increasing truck competitiveness. The main objective of the IMPERIUM project (IMplementation of Powertrain Control for Economic and Clean Real driving EmIssion and ConsUMption) is to achieve fuel consumption reduction by 20% (diesel and urea) whilst keeping the vehicle within the legal limits for pollutant emissions. The approach relies on three stages targeting the improvement of the control strategy: * Direct optimisation of the control of the main components (engine, exhaust after-treatment, transmission, waste heat recovery, e-drive) to maximize their performances. * Global powertrain energy manager to coordinate the different energy sources and optimize their use depending on the current driving situation. * Providing a more comprehensive understanding of the mission (eHorizon, mission-based learning) such that the different energy sources can be planned and optimized on a long term. The IMPERIUM consortium consist of major European actors and is able to provide a 100% European value chain for the development of future powertrain control strategies for trucks.

Keywords: powertrain control,ehorizon,heavy duty vehicles,optimised emission
Bottom-up hybrid control and planning synthesis with application to multi-robot multi-human coordination (BUCOPHSYS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Sweden
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-03-01
End date: 2020-08-31
Duration (months): 66.0
Total project cost (EUR): 1498729.0
EU funding (EUR): 1498729.0
Participants: 1
Project status: CLOSED

Current control applications necessitate the treatment of systems with multiple interconnected components, rather than the traditional single component paradigm that has been studied extensively. The individual subsystems may need to fulfil different and possibly conflicting specifications in a real-time manner. At the same time, they may need to fulfill coupled constraints that are defined as relations between their states. Towards this end, the need for methods for decentralized control at the continuous level and planning at the task level becomes apparent. We aim here towards unification of these two complementary approaches. Existing solutions rely on a top down centralized approach. We instead consider here a decentralized, bottom-up solution to the problem. The approach relies on three layers of interaction. In the first layer, agents aim at coordinating in order to fulfil their coupled constraints with limited communication exchange of their state information and design of appropriate feedback controllers; in the second layer, agents coordinate in order to mutually satisfy their discrete tasks through exchange of the corresponding plans in the form of automata; in the third and most challenging layer, the communication exchange for coordination now includes both continuous state and discrete plan/abstraction information. The results will be demonstrated in a scenario involving multiple (possibly human) users and multiple robots. The unification will yield a completely decentralized system, in which the bottom up approach to define tasks, the consideration of coupled constraints and their combination towards distributed hybrid control and planning in a coordinated fashion require for new ways of thinking and approaches to analysis and constitute the proposal a beyond the SoA and groundbreaking approach to the fields of control and computer science.

Keywords: temporal logic based planning and control,hybrid control systems,multi agent control,distributed task planning using formal verification,formal methods for control and planning