Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Semantic-Aware Intelligent Localization and Sensing towards 6G (SAILS-6G)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 1
Project status: SIGNED

The rise of applications like smart cities and augmented reality has emphasized the critical importance of precise, low-latency localization and sensing (L&S) in the context of 6G communications. Meeting L&S demands involves inundating transceivers with extensive data from sources like pilot signals and sensors, creating redundancy that overwhelms communication networks. Addressing this redundancy is a key aspect of semantic communications, aiming to enhance energy efficiency and support 6G technology. Semantic communications prioritize transmitting useful information over mere data transmission. SAILS-6G's goal is to improve the energy efficiency of L&S without compromising utility by leveraging the principles of semantic communications. Historically, L&S optimization has focused on primary KPIs, such as accuracy, neglecting energy efficiency. SAILS-6G bridges this gap by integrating energy efficiency into L&S optimization through three WPs: WP1 addresses energy-constrained optimization issues using optimization theory tools. WP2 tackles complex nonlinear optimization challenges from WP1, employing learning structures. WP3 extends energy-efficient L&S algorithms from WP1 and WP2, considering distributed processing and privacy constraints. The applicant's expertise in information theory, optimization theory, and privacy-preserving learning, along with the supervisor's localization knowledge, supports these WPs. The outcome is optimized transceivers, reducing energy consumption while meeting L&S requirements. Their performance is evaluated against traditional methods and theoretical bounds. The ultimate aim is to introduce a groundbreaking framework for semantic L&S widely accepted in the scientific community, marking a significant field advancement. Building this framework boosts the applicant's scientific impact and strengthens his managerial, educational, and research skills, facilitated by the supervisor's network, advancing his journey towards a professorship.

Keywords: 6g localization and sensing semantic communications energy efficiency statistical learning theory non linear optimization estimation theory privacy distributed processing
Evolution of shape-defined macromolecules into functional systems (SHAPE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Poland
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-10-01
End date: 2029-09-30
Duration (months): 60.0
Total project cost (EUR): 1499750.0
EU funding (EUR): 1499750.0
Participants: 1
Project status: SIGNED

Functionalities of enzymes are encoded in amino acid sequences and directed by their SHAPEs with complementary binding pockets for specific substrates. Natural enzymes are remarkable catalysts, however, they are typically optimized by evolution to operate under the constraints of the physiological environment of a living system, which strongly limits the scope of their applications in organic synthesis. Here, I propose to develop abiotic enzymes to selectively catalyze chemical transformations in non-physiological environments. The main objective of the project is to use monomer sequence control to fine-tune the SHAPE of abiotic macromolecules to obtain the desired catalytic functionality. This goal will be realised via four work packages: (I) Primary structure control to input information into macromolecules – development of synthetic methods yielding high molar mass, sequence-defined polymers, to deliver abiotic proteins at high scales and numbers. (II) SHAPE control by single chain folding and topology – secondary and tertiary structure evolution by varying the monomer sequence and stereochemistry to tune intramolecular interactions, leading to controlled engineering of globularly folded polymers. (III) Introducing catalytic activity into abiotic polymers – enhancing selectivity and efficiency of catalytic reactions by advancing an outer sphere that surrounds the metal cofactor. (IV) Sequence-function studies using machine learning – delivery of models able to interpret multivariate data that will guide the development of complex catalytic systems to find and predict dependencies inaccessible by conventional methods. Our approach proposes an unexplored method for obtaining abiotic, sequence-defined polymers operating in a non-biological environment whose functions can rival those of natural macromolecules. The study will reveal valuable information on sequence-dependent properties of polymers, to open a field of abiotic enzymes for organic transformations.

Keywords: macromolecules,sequence defined polymers,single chain folding,molecular topology,catalytic functions
dialoguing@rts – Advancing Cultural Literacy for Social Inclusion through Dialogical Arts Education (d@rts)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Norway,Belgium,Germany,Finland,Italy,Serbia,New Zealand,Uganda,Portugal
Call: Promoting cultural literacy through arts education to foster social inclusion (HORIZON-CL2-2023-HERITAGE-01, 2023)
Start date: 2024-01-01
End date: 2027-06-30
Duration (months): 42.0
Total project cost (EUR): 2999968.75
EU funding (EUR): 2999968.75
Participants: 27
Project status: SIGNED

d@rts is a catalyst for increasing social cohesion and inclusion, using embodied performing arts activities to develop cognitive and affective cultural literacy. We recognise that the performing arts encompass mass-market consumer goods, as well as non-linguistic, embodied and social activities, providing massive opportunities for inclusive participation. Our target groups comprise actors of all ages and social positions, especially in the school system and in community arts initiatives. We will empower these groups to be artistically active, dialogically related and culturally literate, giving them tools and motivation to improve their own situations and those of others within the overall frame of a cohesive European society, informed by global perspectives. Using the post-colonial insight that culture is necessarily heterogeneous, d@rts has four related objectives: 1. Understand how performing arts activities relate to cultural literacy in official discourse and documents across partner countries 2. Use this understanding to build dialogues and co-create physical and digital actions with heterogeneous groups within our target audience 3. Develop assessment tools for these actions, enabling measurable growth in cultural literacy 4. Use our findings in recommendations for cultural and educational policies that build long-term social cohesion and inclusion Based on these objectives, the overall outputs comprise: 1. Documentary, survey and participatory research findings 2. Performative DIALOGART actions for cultural literacy 3. Policy and practice recommendations to increase social cohesion via cultural literacy actions inspired by the performing arts d@rts imagines new futures and creates hope and social cohesion through performing arts education. By creating participatory spaces and facilitating dialogues, we empower voices seldom heard. d@rts thus advances cultural literacy, and enhances social cohesion and resilience, to build an inclusive future for Europe.

Keywords: arts education music education dance education drama education
A EUROPEAN CYBER RESILIENCE FRAMEWORK WITH ARTIFICIAL INTELLIGENCE -ASSISTED ORCHESTRATION & AUTOMATION FOR BUSINESS CONTINUITY, INCIDENT RESPONSE & INFORMATION EXCHANGE (PHOENI2X)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Increased Cybersecurity
Action type: Research and Innovation actions
Countries involved: Greece,Cyprus,Spain,Germany,Ireland,Norway
Call: Dynamic business continuity and recovery methodologies based on models and prediction for multi-level Cybersecurity (HORIZON-CL3-2021-CS-01, 2021)
Start date: 2022-07-01
End date: 2025-06-30
Duration (months): 36.0
Total project cost (EUR): 4820000.0
EU funding (EUR): 4820000.0
Participants: 18
Project status: SIGNED

PHOENi²X aims to design, develop, and deliver a Cyber Resilience Framework providing Artificial Intelligence (AI) - assisted orchestration, automation & response capabilities for business continuity and recovery, incident response, and information exchange, tailored to the needs of Operators of Essential Services (OES) and of the EU Member State (MS) National Authorities entrusted with cybersecurity. Through the deployment PHOENi²X Cyber Resilience Centres (PHOENi²X CRCs), OES will gain: (i) enhanced Situational Awareness with AI-assisted Prediction, Prevention, Detection & Response capabilities, and business risk impact assessment-based prioritisation; (ii) proactive and reactive Resilience Automation, Orchestration, and Response (ROAR) mechanisms, providing Business Continuity, Recover and Cyber & Physical Incident Response; (iii) Increased Preparedness through relevant Serious Games and realistic Resilience Cyber Range (RCR) Assessment & Training; (iv) timely and actionable Information Exchange between OES, National Authorities and EU actors, leveraging interoperable and standardised alerting and reporting mechanisms and processes.

Keywords: incident response,soar,playbooks,cti,situational awareness,cyber range,training and awareness,attack prediction
Astrocytes in Reward and their Bidirectional Relationship with the Dopaminergic System (ASTROCYTES-REWARD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Israel
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-11-01
End date: 2028-10-31
Duration (months): 60.0
Total project cost (EUR): 2340575.0
EU funding (EUR): 2340575.0
Participants: 1
Project status: SIGNED

Astrocytes are currently investigated in a range of questions extending far beyond their traditional 'housekeeping' functions. We have contributed to expanding the horizon of functions attributable to astrocytes, and have recently identified a novel and unexpected role for hippocampal astrocytes in signaling the location of reward. This pioneering ERC project, will drive considerable progress in an important and completely unknown facet of reward-related information processing: the roles of hippocampal astrocytes in signaling reward, and their interaction with dopamine, the main player in the reward system. In Aim 1 we will define the role of hippocampal astrocytes in the perception of reward. We will test whether astrocytes can encode the presences of reward irrespective of its location, based on non-spatial (auditory) cues. By simultaneously imaging both astrocytes and neurons, we will delineate the spatio-temporal interplay between them in reward representation, and examine the projection-specific effect of astrocytes in rewarded behavior. Work on Aim 2 will delineate the effects of the dopaminergic system on astrocytes. We will comprehensively analyse the distribution of dopamine receptors on astrocytes and the astrocytic response to tonic vs. phasic dopaminergic signals. We will also perform simultaneous imaging of dopamine levels and astrocyte Ca2+ dynamics in different behavioral states. Aim 3 will determine how astrocytes mediate the effects of the dopaminergic system. We will do that by manipulating astrocytic activity measure pre-synaptic dopamine axonal release in the hippocampus and its influence on the poorly understood phenomenon of over-representation of reward locations by neuronal place cells. Our published work and our new (unpublished) results generate the conceptual basis for this proposal and demonstrate its technical feasibility. Achieving our goals will provide fundamental insights into the roles of astrocytes in information processing.
Dark matter and neutrino experiment with monolithic arrays of cryogenic detectors (DANAE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Italy,France
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-10-01
End date: 2028-09-30
Duration (months): 60.0
Total project cost (EUR): 2587500.0
EU funding (EUR): 2587500.0
Participants: 3
Project status: SIGNED

In Particle Physics the research on neutrinos is continuously producing new results and further discoveries might just be around the corner. They could provide answers to crucial questions on how matter was created in the Universe or reveal the existence of new types of fundamental interactions between elementary particles. Possibly even more intriguing is the search for Dark Matter, an unknown form of matter that, according to astrophysical observations, outweighs the ordinary matter in our Universe by more than 5 times. Dark Matter particles have been searched for since 30 years, and invariably eluded discovery. DANAE intends to enable unprecedented sensitivities in the study low energy neutrinos and in the search for Dark Matter, by measuring the tiny nuclear recoils that these particles induce in their passage through matter. The goal is to create a pilot experiment by introducing for the first time monolithic, and at the same time highly segmented, arrays of thousands multiplexed superconducting detectors. If successful, precision measurements of a recently discovered process, the coherent and elastic neutrino scattering off nuclei, could be made. In the Dark Matter field new hypothesized particles could be sensed, lighter than those searched and never found so far.

Keywords: neutrinos,dark matter,cryogenic detectors,kinetic inductance detectors
Development of Environmental and Socio-economic Methodology for Island Economy Energy Metabolism. Construction Scenarios for Resilient Hydrogen Economy for Cuba (M4IEMA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Finland
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 242116.8
EU funding (EUR): 242116.8
Participants: 1
Project status: SIGNED

Islands are hotspots of biocultural diversity. The SIDS Lighthouses Initiative provides a global framework for energy transition on islands and the Smart Islands Initiative was developed by the European Union to encourage innovative island solutions that support sustainable economic growth. This challenge has been underlined in various IPCC and UN reports because island economies are vulnerable to global climate changes. The research project is highly relevant and actual. Worldwide, more than 700 million people live on islands which are frequently considered ideal environments for the transition to 100% renewable energy systems. Furthermore, island economies need to be energy resilient for instance, to invest in energy diversity, infrastructure, research and development, and governance. A foresight methodological framework development to integrate the political, economic, socio, technical, environmental, cultural and managerial systems (PESTECM) is a critical phase to go beyond island energy metabolism and foster the development of synergetic resilience. This project aims to create a methodology for island’s synergetic resilience assessment considering the synergies and trade-offs between different energy resource-use patterns and sectoral development paths. In addition, this project will implement the novel validated and developed methods in previous research projects by the research team, and evaluate the potential dynamizer role of hydrogen in island developing countries from PESTECM approach and its fostering impact. Last but not least, it will be constructing synergetic resilience scenarios for future development paths for Cuba, as a study case, in the interlinked PESTECM approach for the multisectoral planning to achieve sustainable island metabolism.

Keywords: sustainability assessment methodology foresight studies renewable energy sources island s energy metabolism
Endothelial metabolism dictates the bone marrow niche and the plaque microenvironment (ENDOMET-STEER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-11-01
End date: 2028-10-31
Duration (months): 60.0
Total project cost (EUR): 1528006.25
EU funding (EUR): 1528006.25
Participants: 2
Project status: SIGNED

Inflammation is an important driver of atherosclerosis, the primary cause of global morbidity and mortality in emerging and developed countries. New strategies to reduce atherosclerotic cardiovascular disease (CVD) risk are therefore eagerly needed. I recently found that atherogenic inflammatory stimuli rewire cellular metabolism in endothelial cells (ECs) and thereby contribute to atherosclerosis progression. Defining the intricate link between EC inflammation, metabolic rewiring and functional consequences for the vasculature will open new avenues for therapeutic strategies in CVD. My recent work shows that CVD-associated metabolic changes in ECs can affect their secretome. In turn, the endothelial secretome disrupts both stem cell function in the bone marrow niche and macrophage activation in the plaque microenvironment, two highly vascularized tissue compartments that drive atherosclerosis progression. Based on these findings, I hypothesize that CVD-associated EC metabolic changes impact the micromilieu in both tissue compartments, propagating the proinflammatory state in CVD patients. With this ERC project I aim to define (1) how EC metabolism is affected in atherosclerosis, (2, 3) what the impact of altered EC metabolism is for stem cell function in the bone marrow niche and for macrophage activation in the plaque, and ultimately (4) to define how interventions in EC metabolism improve tissue function and halt CVD development. I will apply innovative 3D organ-on-chip models that accurately reflects the human bone marrow and plaque microenvironment. By combining this with a unique collection of human ex-vivo atherosclerotic plaques, human bone marrow cells and novel transgenic in-vivo models, I will generate essential new insights that help to understand the development of atherosclerotic CVD. Hereby, this ERC will yield important insights that the field urgently awaits to develop novel therapeutic strategies for the reduction of the burden of CVD.

Keywords: atherosclerosis,endothelium,inflammation,metabolism,bone marrow,macrophages
Engineering metal halide PEROvskites by VAPour deposition (PEROVAP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2024-04-01
End date: 2029-03-31
Duration (months): 60.0
Total project cost (EUR): 1999843.75
EU funding (EUR): 1999843.75
Participants: 1
Project status: SIGNED

Metal halide perovskites (MHPs) have been in the spotlight of scientific research for over a decade due to their remarkable properties and performance in solar cells. Their future relies on a deeper understanding of their fundamental properties, better control of their structure, and implementation by scalable deposition methods. While most research efforts are dedicated to the solution processing of MHPs, vapour deposition holds many benefits. It is a solvent-free, scalable method of high industrial relevance offering high throughput, homogeneity, material economy, safety, yield and controllability. Despite these clear advantages, the development of engineering approaches to precisely control the properties of MHPs by vapour deposition remains in its infancy. In PEROVAP, I will develop novel routes for engineering MHPs by vapour deposition and the fundamental understanding of their growth and crystallisation, thus enabling new material structures with tailor-made properties. I will establish structural control over the phase, orientation and microstructure of MHPs by additive engineering, and develop a new class of perovskite-organic hybrid semiconducting composites. I will also demonstrate efficient, controllable n- and p- electrical doping of vapour deposited MHPs and create graded MHP layers with tailored optoelectronic properties and energetic landscape. To realise this, I propose a unique combinatorial fabrication-characterisation methodology for their in-situ spectroscopic characterisation. This approach will allow to efficiently explore the multi-dimensional parameter space required to engineer the MHP properties, and enable the development of the fundamental understanding of the film formation processes. Finally, to reveal the structure-property relations, the engineered MHPs will be integrated in novel solar cell architectures. The approaches developed in PEROVAP will open a new path for MHP electronics and optoelectronics far beyond state-of-the-art.

Keywords: metal halide perovskites vapour deposition engineering composites doping spectroscopy electronics optoelectronics photovoltaics