Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Neuropsychiatric disorders are a heterogeneous group of mental pathologies that demand prolonged and treatments that are frequently ineffective. Elucidating the cellular and molecular mechanisms under (NanoPSYCH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-06-01
End date: 2021-09-30
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

Neuropsychiatric disorders are a heterogeneous group of mental pathologies that demand prolonged and treatments that are frequently ineffective. Elucidating the cellular and molecular mechanisms underlying these diseases is paramount for a precise classification of subgroups of patient and application of appropriate therapeutic strategies. The role of the immune system in the pathophysiology of neuropsychiatric disorders has been the subject of debate for many decades. However, recent recognition of antibody-mediated central nervous system (CNS) disorders has fueled the search for a subgroup of patients with an antibody-mediated psychiatric illness. CNS autoantibodies have demonstrated to be pathogenic by disrupting the functional or structural integrity of synapses and their study has become an exciting research topic. Several aspects about the mode of action of these pathogenic autoantibodies remain unsolved, such as their accumulation in specific brain regions. An important factor for this preferential retention could be the influence of brain extracellular space (ECS), a component of the brain that has remained largely inaccessible for exploration due to its complex organization and technical limitations for its examination in living tissue. Recent advances in Nanotechnology and Biotechnology have given rise to unique tools to tackle the study of complex biological systems, thus we are now in a privileged position to explore the architecture of the ECS and the dynamics of CNS autoantibodies into brain tissue. The aim of this project is to define how the dynamics of CNS autoantibodies is affected by the ECS architecture in specific brain regions. This goal will be accomplished by using an original strategy combining classical imaging approaches to map the distribution of CNS autoantibodies between different brain structures and nanoparticle monitoring techniques to visualize at the nanoscopic scale the dynamics of CNS autoantibodies and the ECS architecture.

Keywords: psychosis,autoimmunity,brain extracellular space
Beyond Colours and Flavours on Supercomputers (BCFS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2022-09-30
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: CLOSED

We propose precision lattice QCD computations aiding the search for new physics beyond the Standard Model. In particular, we will address currently observed anomalies such as those displayed in the anomalous magnetic moment of the muon and lepton flavour universality tests in semi-leptonic B meson decays. We will further supplement searches for new physics through the computation of hadronic inputs, which combined with experimental results allow the determination of elements of the Cabibbo-Kobayashi-Maskawa matrix, thereby providing precision tests of the standard model. We will compute a large set of hadronic form factors of semi-leptonic B(s) and D(s) meson decays including pseudo-scalar and vector final states. State-of-the-art computations of these have two major shortcomings: the use of effective theories for the b-quark, and the treatment of vector final states as QCD-stable particles. We will eliminate the former of these by utilising very fine lattices which allow for the direct simulation of the b-quark near its physical mass. The latter will be addressed by merging specialist expertise in the computation of such form factors with that of hadronic scattering processes. This will result in the first calculation that takes the unstable nature of the vector final states in QCD into account. This is of paramount importance in order to address the observed anomalies in the B to D* and B to K* decays. We will compute the full basis of possible currents thereby providing standard model predictions as well as inputs for tests of beyond the standard model theories. Further, we will use the approach of massive QED in lattice QCD computations to provide an independent cross check of the electromagnetic corrections to the hadronic vacuum polarisation. This work will provide vital inputs in searches for physics beyond the standard model which are needed to fully exploit large ongoing experiments at the Large Hadron Collider and at facilities in Japan and the US.

Keywords: quark flavour physics,anomalous magnetic moment,lattice quantum field theory,supercomputing
Shared Access Terrestrial-Satellite Backhaul Network enabled by Smart Antennas (SANSA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Future Internet: Software, hardware, Infrastructures, technologies and services
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Spain,Switzerland,Greece,Greece,Luxembourg,United Kingdom
Call: Smart optical and wireless network technologies (H2020-ICT-2014-1, 2014)
Start date: 2015-02-01
End date: 2018-01-31
Duration (months): 36.0
Total project cost (EUR): 3557680.0
EU funding (EUR): 2983930.0
Participants: 8
Project status: CLOSED

The aim of SANSA project is to boost the performance of mobile wireless backhaul networks in terms of capacity and resilience while assuring an efficient use of the spectrum. Recently, a global mobile traffic increase of 11-fold between 2013 and 2018 was predicted, so novel solutions are required to avoid backhaul becoming the bottle neck of future mobile networks. The solution envisaged in SANSA is a spectrum efficient self-reconfigurable hybrid terrestrial-satellite backhaul network based on three key principles: (i) a seamless integration of the satellite segment into terrestrial backhaul networks; (ii) a terrestrial wireless network capable of reconfiguring its topology according to traffic demands; (iii) a shared spectrum between satellite and terrestrial segments. This combination will result in a flexible solution capable of efficiently routing the mobile traffic in terms of capacity and energy efficiency, while providing resilience against link failures or congestion and easy deployment in rural areas. Therefore, we will develop novel smart antennas, dynamic radio resource management and data-based shared access techniques for enabling the spectrum sharing among both segments, as well as efficient management and routing solutions for the hybrid network. These studies will yield to the implementation and demonstration of the two key components proof of concepts: (i) low-cost smart antennas (to be deployed in terrestrial nodes) with beam and null-steering capabilities for interference mitigation between satellite and terrestrial transceivers and network topology reconfiguration; (ii) hybrid network manager capable of controlling the resources of the hybrid network. Besides indirectly allowing the traffic increase to the mobile users, the SANSA project will set the path for a win-win collaboration between satellite and terrestrial operators that will strengthen both European sectors and also their related industries such as equipment manufacturers.

Keywords: backhaul network technologies,satellite comunications
Business Plan for a commercial space telescope (Public Telescope)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: SME instrument
Countries involved: Germany
Call: SME Instrument (H2020-SMEINST-1-2015, 2015)
Start date: 2015-07-01
End date: 2015-10-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The Hubble Space Telescope (HST) is a masterpiece for astronomy and astrophysics and also for public outreach and education, serving as an inspiration for all mankind. However, the HST is coming to age and will have to be retired soon. Unfortunately, the James Webb Space Telescope cannot be considered a follow-on telescope to the HST as its observing spectrum will be mostly in the infrared spectrum only while the HST can observe in the ultraviolet (UV) and the visual spectrum too. Consequently the UV-community will be left behind or even blind. Acknowledging that professional UV-astronomers are mostly interested in observing celestial objects eof the milky way and nearby galaxies and that the hobby astronomer community as well as the general public's interest in astronomy is centered on bright objects offers an interesting opportunity to establish a follow-on telescope to the HST, which can be extremely cost-effective. This is due to two reasons: a) a telescope focusing on bright objects is not required to work with a huge aperture and b) recent advances in electronics, sensors, light-weight structures etc. have enabled the rise of small satellite systems. By combining these aspects an interesting concept arises, which is the aim of the project "Public Telescope": • Sub-meter space telescope for UV/VIS/NIR spectroscopy and imaging • Internet-based service-platform for order and configuration • Combination of huge scientific need with a sustainable commercial potential The opportunity is now! PlanetLabs and similar initiatives in the US showcase that the time is right to launch such endeavors - if the Europeans do not act now, then it will be the US that will be the first and likely there is no early market for two or more systems. We need the feasibility study for: • Concretion of user requirements • Development of a functional mission concept • Estimate of the overall project cost • Development of product, price and quantity structures

Keywords: commercial satellite based services,astronomy,space telescope,ultra violet
ALMA – The key to the Sun’s coronal heating problem. (SolarALMA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Norway
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-09-01
End date: 2021-08-31
Duration (months): 60.0
Total project cost (EUR): 1995963.75
EU funding (EUR): 1995963.75
Participants: 1
Project status: CLOSED

How are the outer layers of the Sun heated to temperatures in excess of a million kelvin? A large number of heating mechanisms have been proposed to explain this so-called coronal heating problem, one of the fundamental questions in contemporary solar physics. It is clear that the required energy is transported from the solar interior through the chromosphere into the outer layers but it remains open by which physical mechanisms and how the provided energy is eventually dissipated. The key to solving the chromospheric/coronal heating problem lies in accurate observations at high spatial, temporal and spectral resolution, facilitating the identification of the mechanisms responsible for the transport and dissipation of energy. This has so far been impeded by the small number of accessible diagnostics and the challenges with their interpretation. The interferometric Atacama Large Millimeter/submillimeter Array (ALMA) now offers impressive capabilities. Due to the properties of the solar radiation at millimeter wavelengths, ALMA serves as a linear thermometer, mapping narrow layers at different heights. It can measure the thermal structure and dynamics of the solar chromosphere and thus sources and sinks of atmospheric heating. Radio recombination and molecular lines (e.g., CO) potentially provide complementary kinetic and thermal diagnostics, while the polarisation of the continuum intensity and the Zeeman effect can be exploited for valuable chromospheric magnetic field measurements. I will develop the necessary diagnostic tools and use them for solar observations with ALMA. The preparation, optimisation and interpretation of these observations will be supported by state-of-the-art numerical simulations. A key objective is the identification of the dominant physical processes and their contributions to the transport and dissipation of energy. The results will be a major step towards solving the coronal heating problem with general implications for stellar activity.
In Video Veritas – Verification of Social Media Video Content for the News Industry (InVID)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Austria,Spain,Germany,Germany,Greece,France
Call: Technologies for creative industries, social media and convergence (H2020-ICT-2015, 2015)
Start date: 2016-01-01
End date: 2018-12-31
Duration (months): 36.0
Total project cost (EUR): 3765706.25
EU funding (EUR): 3115737.5
Participants: 9
Project status: CLOSED

In video veritas, if we divert the old Latin saying: In video, there is truth! The digital media revolution and the convergence of social media with broadband wired and wireless connectivity are bringing breaking news to online video platforms; and, news organisations delivering information by Web streams and TV broadcast often rely on user-generated recordings of breaking and developing news events shared by social media to illustrate the story. However, in video there is also deception. Access to increasingly sophisticated editing and content management tools, and the ease in which fake information spreads in electronic networks requires reputable news outlets to carefully verify third-party content before publishing it, reducing their ability to break news quickly while increasing costs in times of tight budgets. InVID will build a platform providing services to detect, authenticate and check the reliability and accuracy of newsworthy video files and video content spread via social media. This platform will enable novel newsroom applications for broadcasters, news agencies, web pure-players, newspapers and publishers to integrate social media content into their news output without struggling to know if they can trust the material or how they can reach the user to ask permission for re-use. It will ensure that verified and rights-cleared video content is readily available for integration into breaking and developing news reports. Validated by real customer pilots, InVID will help protecting the news industry from distributing fakes, falsehoods, lost reputation and ... lawsuits. The InVID platform and applications will be validated and qualified through several development and validation cycles. They will be pilot-tested by three leading institutions in the European news industry ecosystem: AFP (the French News Agency), DW (Deutsche Welle), and APA (the Austria Press Agency), and will create new exploitation possibilities for all consortium members.

Keywords: video verification,rights management,user generated content,news and media industries
Ancient Saharan Art – Decoding Art through Theoretically-sounded Archive (ASArt-DATA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-01
End date: 2021-12-31
Duration (months): 36.0
Total project cost (EUR): 244269.0
EU funding (EUR): 244269.0
Participants: 2
Project status: CLOSED

Rock art is one of the most fascinating and widespread cultural manifestations of humankind: it offers a unique and significant visual archive into the social and symbolic worlds of past human societies. Yet, the integration of rock art studies within the archaeological and anthropological domain faces crucial challenges. The complexity of documentation and publication, as well as of dating, have hampered its immense potential as archaeological source. The lack of a theoretically sound interpretive perspective, linking local peculiarities with general overviews has reduced its powerful capacity of transmitting human thoughts and emotions. This is particularly true for the Sahara, where outstanding paintings and engravings are now inaccessible for security reasons, at risk of destruction, ASArt-DATA aims to provide a flexible tool for the in-depth analysis of the corpus of the Saharan rock art, produced by the pastoral communities ca. 6300-850 BCE. Relying on the complete archive of Acacus and Messak (SW Libya), and on other sets of data, for the first time this Rock Art will be investigated with an original multidisciplinary and systematic approach combining Archaeology, Anthropology, Visual Studies, and Digital Humanities. A cornerstone of ASArt-DATA will be the building of the open access webAtlas of Saharan rock art , properly customized for scientific research, CRM, dissemination and communication. Through the intensive theoretical training in Art iconography, a sound and innovative method of exploration of the artworks will be applied, and codes of representation will be reconnected with their geographical, environmental and archaeological context. The analysis will follow a bottom-up approach, with a main focus on human representation. The actions of ASArt-DATA aspire to strengthen the connection between archaeological and anthropological studies and between academy and society, thanks to the deployment of the underdeveloped potential of Rock Art.

Keywords: rock art,holocene,sahara,pastoralism,human representation,anthropology,visual studies,digital humanities,cultural heritage,webatlas,gender,interdisciplinary,intersectoral,er career
Securing water for food and safety with the world's most advanced soil moisture information derived from satellites (WATER4AGRI)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: SME instrument
Countries involved: Netherlands
Call: Engaging SMEs in space research and development (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2017-10-01
End date: 2019-03-31
Duration (months): 18.0
Total project cost (EUR): 1914375.0
EU funding (EUR): 1340062.5
Participants: 1
Project status: CLOSED

European agriculture is facing important challenges in the coming decades linked to our changing climate. Periods of droughts and floods will further increase which threaten production and require a smart usage of our vulnerable water resources. Climate change also stimulates crop disease, which causes farmers to use more pesticides and in turn endangers water quality and impacts people's health and the environment. Satellite Remote Sensing has a crucial role to play in tackling these challenges. At VanderSat we have developed a method to provide accurate high-resolution images of soil moisture, at any place on Earth 24/7 a year. Soil moisture is a key indicator for the physical status of a plant, and has a strong predictive value with respect to crop yield and weather conditions including flooding and droughts. By combining microwave data obtained from different satellites – including the ones in the Copernicus Sentinel constellation – we are revealing a revolutionary data set that can be used to retrieve key information about the water availability for crops at field level. This data is crucial for improving the accuracy of Agricultural (Ag.) models that are the backbone of modern agribusiness. Through the WATER4AGRI project we want to lift the technology to TRL9 by: (1) scaling VanderSat soil moisture for implementation in Ag. models and, (2) demonstrating the effectiveness of VanderSat in the two most widespread Ag. models. With VanderSat our customers will be able to accurately predict crop yield, pesticide requirements, droughts and flooding and, most important, reduce climate related risks for their businesses. VanderSat is creating business opportunities that were unimaginable before, like reducing crop risks through smart re-insurance strategies and integrated pest management. In doing this VanderSat impacts agribusiness in the most important dimension: improving yield and the overall profit or loss of the operation.

Keywords: global soil moisture data,satellite remote sensing,esa sentinel constellation,near real time,high spatio temporal resolution,precision agriculture
Gastrointestinal Tract on Chip - An automated microfluidics-based modular device for complete simulation of the processes of digestion and absorption of orally ingested bioactive compounds (GASTRIC)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Other Widening
Action type: Marie Skłodowska-Curie actions
Countries involved: Portugal
Call: Widening Fellowships (H2020-WF-02-2019, 2019)
Start date: 2020-10-16
End date: 2022-10-15
Duration (months): 24.0
Total project cost (EUR): 159815.04
EU funding (EUR): 159815.04
Participants: 1
Project status: CLOSED

People can only ingest food through the oral cavity, and oral administration remains the preferred route for the delivery of drugs or dietary supplements. However, orally ingested compounds must first survive digestion and then be absorbed at the small intestine to reach the systemic circulation. This proposal aims to develop and fabricate the first automated microfluidics-based device for complete simulation of the processes of digestion and intestinal absorption of orally ingested bioactive compounds. The innovation lies on the capacity to simulate the process in full and, on the introduction of integrated sensors for online, real-time monitoring of the pH, barrier integrity, intestinal permeation and cellular responses. In addition, the use of primary cells will allow to create disease models and patient-specific tissues for personalised medicine. Co-cultures with the gut microbiome will allow to assess the effect of the ingested compounds on commensal bacteria and of the latter in nutrient digestion. The work will be conducted at the International Iberian Nanotechnology Laboratory in Portugal, with two secondments projected at the University of Southampton for 4 months, and intersectorally at GlaxoSmithKline, in Stevenage, UK for 2 months. The device will offer the possibility to study minute sample amounts, with high resolution and with the potential for high-throughput analysis, which is key for its adoption by large pharmaceutical and food industries with high economic and social impact. The proposal aligns with the societal challenges 1 (Health, demographic change and wellbeing) and 2 (Food security) of the current Horizon 2020 work programme. The work is multidisciplinary and the combination of learning through research and a comprehensive training plan will strongly improve the applicant's researcher profile and career prospects.

Keywords: microfluidics,organ on chip,in vitro models