Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The Economics of the Intelligent Transportation Services (ECOINTELS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-12-01
End date: 2020-11-30
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

Technological advancements have enabled new flexible and demand-responsive transportation services, whose significance on both urban and rural transportation systems have been increased rapidly due to the successful transport network companies such as Uber and Lyft and due to innovative public transportation operators developing automated demand-responsive services with public-private-partnerships. At the same time, there has been also increasing interest in these services in several academic disciplines like operations research, transportation economics and computer science. Recently, research has focused on modelling these services and related pricing policies, and on developing algorithms for optimal vehicle routing and demand management. During the fellowship period, the object is to achieve deeper understanding on the economics of the intelligent transportation services by extending the economic models of the automated demand responsive transportation and by adopting recently developed simulation models of the Max-Planck Institute, which utilize trip origin-destination data collected in Germany, South-Africa and elsewhere.

Keywords: transportation economics,intelligent transportation services,public transportation,demand responsive transportation,shared taxis,discrete choice,real time traffic data
Heterogeneity in fimbrial length and abundance as a generic regulator of E. coli surface colonization (FIMBUG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-01-01
End date: 2019-12-31
Duration (months): 24.0
Total project cost (EUR): 185857.2
EU funding (EUR): 185857.2
Participants: 1
Project status: CLOSED

The aim of my research is to identify generic and physical mechanisms that regulate bacterial colonization and subsequent biofilm formation on biomaterial surfaces. This is an emerging problem in modern health care since biofilm implant-related infections are very difficult to eradicate and thus a main contributor to the development and spreading of antibiotic resistance. A key player is fimbriae; these hair-like surface organelles found on many bacteria are known to strongly promote biofilm formation, which is commonly attributed to fimbriae forming strong surface bonds. By recording in 3D the binding of single bacteria to nanopatterned surfaces we observed that this is not necessarily true; We found that fimbriae due to their heterogeneous distribution in length, rather then forming strong bonds provide bacteria a mean to adjust their surface adhesion, shifting between monovalent, loose and mobile binding to firm multivalent immobile binding modes in response to different flow conditions. This suggests a so far unexplored, regulatory role of fimbriae in the surface colonization process. My overarching aim is therefore to understand the influence of this mechanism on bacterial surface colonization. Specifically, I will test the hypothesis that physical and chemical/colloidal interactions are reflected in these structures and their biological function, providing bacteria evolved roles; In this case, that bacteria with certain fimbrial expression are fitter to be colonizers of certain environmental niches. To investigate this I will introduce new methods, allowing simultaneous read-out of a single-bacterium fimbrial expression and tracking of its movement in 3D. I foresee that this project and the training actions described herein will be the basis for a future scientific career focused on unraveling the intricate interplay between bacteria and their host surfaces.

Keywords: e coli,fimbriae,bacterial biofilm formation,surface colonization,physical regulation of biological systems
Prediction of AF incidence using PR interval measurements, echocardiographic data and biomarker profiles: Analyses within epidemiological Framingham Heart Study and LIFE Health Care Study cohorts (SAECG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,United States
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2022-12-01
Duration (months): 36.0
Total project cost (EUR): 264669.12
EU funding (EUR): 264669.12
Participants: 2
Project status: CLOSED

Atrial fibrillation (AF) may be categorized as an epidemic disease associated with an increased risk for heart failure, thromboembolism, dementia and mortality. The underlying mechanisms behind AF describe multiple pathological states leading to various remodeling processes. One of the easiest available diagnostical tools is an electrocardiogram (ECG). Numerous P wave indices have been identified, demonstrating associations with increased risk for adverse cardiovascular outcomes and mortality. Prolonged signal-averaged P wave duration (SAPWD) measured from the non-invasive signal averaged electrocardiogram (SAECG) using a vector composite of filtered orthogonal leads accurately measures cardiac activation times. In comparison with analysis of a standard 12-lead ECG, the SAECG is superior in detection of P wave prolongation as a risk marker for AF. However, there are only limited data analyzing this issue. Current project is aimed to perform P wave SAECGs in Framingham Heart Study (Boston, US) and LIFE Health Care Study (Leipzig, Germany) and to investigate their role in AF incidence. Furthermore, estimation of corresponding lifetime risk will be performed using multistate modeling phenomapping of AF, e.g. classification of AF patients based on a broad range of data (clinical, laboratory, ECG, echocardiography, biomarkers) predicting adverse clinical outcomes. The current project represents an innovative and authentic multidisciplinary research in AF and includes different future perspectives. It paves the way for fruitful international cooperation with Framingham cohort - the one the most renowned epidemiological studies, intensive exchange of experience and researcher mobility as well as academical and practical implementation of cardiovascular epidemiology and prevention at European institution.

Keywords: atrial fibrillation,electrocardiography ecg,pr interval,p wave indices,risk stratification,endophenotype,epidemiology,prevention,biomarkers
Urban Logistics as an on Demand Service (ULaaDS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Italy,Austria,Germany,Germany,Germany,Belgium,Norway,Belgium,Romania,Norway,Belgium,Netherlands,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Logistics solutions that deal with requirements of the 'on demand economy' and for shared-connected and low-emission logistics operations (H2020-MG-2019-TwoStages, 2019)
Start date: 2020-09-01
End date: 2024-02-29
Duration (months): 42.0
Total project cost (EUR): 3150390.0
EU funding (EUR): 3149515.0
Participants: 27
Project status: SIGNED

A consortium led by 3 municipalities (pilot cities) committed to zero emissions city logistics (Bremen, Mechelen, Groningen) has joined forces with logistics stakeholders, both established (e.g. UPS) and new comers (e.g. ViaVan) as well as leading academic institutions in EU to accelerate the deployment of novel, feasible, shared and ZE solutions addressing major upcoming challenges generated by the rising on-demand economy in future urban logistics. To do so, the ULaaDS project will work on 3 key focus pillars: i) co-creation process to model future on-demand scenarios for urban logistics and definition of relevant ULaaDS delivery solutions through novel toolkit; ii) deployment of 2 ULaaDS solutions co-created (combining new delivery vehicles and novel horizontal collaboration models) through a total of 6 multistakeholder research trials in the 3 pilot cities; iii) assessment of feasible value cases towards urban planning integration (SUMP/SULP). The ULaaDS solutions will be designed complying with a framework of requirements highly aligned with the call topic and ETP ALICE research priorities. The 3 pilot cities propose 2 preliminary ULaaDS solutions building upon their SotA activities solutions to be further concretised through first project pillar: 1) modular innovative cargobikes operated by crowdsourced couriers to enhance logistics efficiency and multimodality in city centres; 2) integration of urban dual transport services (high on-demand distribution requirements of small goods with on-demand shared personal transport - eVans offering pooling for cargo, semiAGVs, public transport) Finally, ULaaDS also involves 4 other satellite cities (Rome, Edinburgh, L’Hospitalet, Bergen) which will also apply the novel toolkit created in ULaaDS as well as the overall project methodology to co-create additional ULaaDS solutions relevant to their cities as well as outlines for potential research trials. ULaaaDS is a project proposal part of ETP ALICE Liaison program.

Keywords: city logistics,urban freight solutions,zero emissions,on demand economy
Next generation of superhard non-CRM materials and solutions in tooling (Flintstone2020)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Ensuring the sustainable supply of non-energy and non-agricultural raw materials
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Austria,Ireland,Ukraine,Sweden,Sweden,Sweden,France,Netherlands,United Kingdom
Call: Materials under extreme conditions (H2020-SC5-2015-one-stage, 2015)
Start date: 2016-02-01
End date: 2020-01-31
Duration (months): 48.0
Total project cost (EUR): 4996180.0
EU funding (EUR): 4996180.0
Participants: 11
Project status: CLOSED

Flintstone2020 aims to provide a perspective for the replacement of two important CRMs – tungsten (W) and cobalt (Co) – which are the main constituents for two important classes of hard materials (cemented carbides/WC-Co, and PCD/diamond-Co), by developing innovative alternative solutions for tooling operating under extreme conditions. Fundamental knowledge on mechanical properties and wear of different tools, gained in machining tests and dedicated experiments from WP1 is passed onto the respective WPs. WP2 will experiment on small samples with 3-9 mm Ø for testing the fundamental behavior of new B-X phases and particularly as a feedback for binder matrix improvement. In WP3 samples (12 mm Ø) will be investigated from individual HPHT runs for characterization and testing to guide high pressure sintering process optimization. The HPHT process and the samples produced are then upscaled to the industrial mass production level in WP4. In WP5, demonstrator cutting tools from full size HPHT synthesis test runs will be prepared via laser cutting and consecutive macro- and microshaping of tool geometry within WP5. In WP6 aspects of environmental benefits in the total life cycle of the superhard materials will be investigated, including health and safety aspects. WP7 will focus on exploitation and dissemination.

Keywords: tungsten,superhard materials,cemented carbides
Toolless Manufacturing of Complex Structures (ToMax)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Technologies for Factories of the Future
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Germany,Austria,Austria,Italy,Finland,France,United Kingdom
Call: Manufacturing processes for complex structures and geometries with efficient use of material (H2020-FoF-2014, 2014)
Start date: 2015-01-01
End date: 2017-12-31
Duration (months): 36.0
Total project cost (EUR): 3157986.0
EU funding (EUR): 3157986.0
Participants: 10
Project status: CLOSED

Lithography based additive manufacturing technologies (L-AMT) are capable of fabricating parts with excellent surface quality, good feature resolution and precision. ToMax aims at developing integrated lithography-based additive manufacturing systems for the fabrication of ceramic parts with high shape complexity. The focus of the project is to unite industrial know-how in the field of software development, photopolymers and ceramics, high-performance light-sources, system integration, life cycle analysis, industrial exploitation and rewarding end-user cases. The consortium will provide 3D-printers with high throughput and outstanding materials and energy efficiency. The project is clearly industrially driven, with 8 out of 10 partner being SMEs or industry. Targeted end-use applications include ceramics for aerospace engineering, medical devices and energy efficient lighting applications. The consortium is aiming to exploit disruptive applications of L-AMT by developing process chains beyond the current state of the art, with the dedicated goal to provide manufacturing technologies for European Factories of the Future. By relying on L-AMT, ToMax the following objectives are targeted: (1) ToMax will provide methods which are 75% more material efficient with respect to traditional manufacturing (2) Are 25% more material efficient with respect to current AMT approaches by using computational modelling to optimize geometries and by providing recyclable wash-away supports. (3) ToMax will provide methods which are 35% more energy efficient that current AMT approaches by developing 50% faster thermal processing procedures. (4) Incorporate recycling for the first time in L-AMT of engineering ceramics Overall, the consortium will provide innovative, resource efficient manufacturing processes. ToMax will develop energy-efficient machinery and processes, with a focus on manufacturing of alumina, silicon nitride and cermet parts with high shape complexity.

Keywords: additive manufacturing,ceramics,recycling
Metal Microstructures in Four Dimensions (M4D)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Denmark
Call: ERC Advanced Grant (ERC-2017-ADG, 2017)
Start date: 2018-10-01
End date: 2023-09-30
Duration (months): 60.0
Total project cost (EUR): 2496519.0
EU funding (EUR): 2496519.0
Participants: 1
Project status: SIGNED

The goals are: 1) to develop a universal laboratory-based 4D X-ray microscope with potentials in the broad field of materials science and beyond; 2) to advance metal research by quantifying local microstructural variations using the new 4D tool and by including the effects hereof in the understanding and modelling of industrially relevant metals. Today, high resolution 4D (x,y,z,time) crystallographic characterization of materials is possible only at large international facilities. This is a serious limitation preventing the common use. The new technique will allow such 4D characterization to be carried out at home laboratories, thereby wide spreading this powerful tool. Whereas current metal research mainly focuses on average properties, local microstructural variations are present in all metals on several length scales, and are often of critical importance for the properties and performance of the metal. In this project, the new technique will be the cornerstone in studies of such variations in three types of metallic materials: 3D printed, multilayered and micrometre-scale metals. Effects of local variations on the subsequent microstructural evolution will be followed during deformation and annealing, i.e. during processes typical for manufacturing, and occurring during in-service operation. Current models largely ignore the presence of local microstructural variations and lack predictive power. Based on the new experimental data, three models operating on different length scales will be improved and combined, namely crystal plasticity finite element, phase field and molecular dynamics models. The main novelty here relates to the full 4D validation of the models, which has not been possible hitherto because of lack of sufficient experimental data. The resulting fundamental understanding of the inherent microstructural variations and the new models are foreseen to be an integral part of the future design of metallic materials for high performance applications.

Keywords: laboratory x ray microscope,local microstructural variations,3d printed metals,multilayered metals,micrometre scale metals,cpfem,md modelling,multiscale modelling
Water Works 2018-2022 in Support of the Water JPI (WaterWorks2017) and of the EC Call SC5-33-2017: Closing the water cycle gap (WaterWorks2017)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Protection of the environment, sustainable management of natural resources, water , biodiversity and ecosystems
Action type: ERA-NET Cofund
Partnership: WaterWorks2017 (ERA-NET)
Countries involved: Estonia,Egypt,Spain,Italy,Israel,South Africa,Ireland,Cyprus,Norway,Tunisia,Finland,Poland,Sweden,Moldova, Republic of,Belgium,Romania,France,Netherlands,Brazil
Call: Closing the water gap (H2020-SC5-2017-OneStageB, 2017)
Start date: 2018-01-01
End date: 2023-12-31
Duration (months): 72.0
Total project cost (EUR): 18949876.01
EU funding (EUR): 6237289.1
Participants: 26
Project status: SIGNED

The WaterWorks2017 project is pooling resources from the 23 participating research programme owners / managers of 19 countries to implement a joint call for proposals, with EU co-funding in the area of closing the water cycle gap. It will support delivery of priorities identified in the Water Joint Programming Initiative (Water JPI) Strategic Research and Innovation Agenda (SRIA) in order to reconcile water supply and demand, both in terms of quantity and quality, and also in terms of space and time. It covers the following sub-themes: • Enabling Sustainable Management of Water Resources; • Strengthening Socio-economic Approaches to Water Management. WaterWorks2017 includes 8 organisations from associated and third countries in an effort to reinforce international cooperation. Additional Activities will also be carried out to further support the implementation and strategy of the Water JPI. The overall aims include: • Supporting the implementation and development of the Water JPI on priorities identified in its SRIA; • Pooling financial resources from participating national and regional research programmes and implementing a co-funded transnational and multi-disciplinary call for research and innovation proposals; • Pooling additional financial resources to implement a joint call for proposals resulting in grants to third parties without EU co-funding (through a Thematic Annual Programming action - TAP); • Overcoming the fragmentation of European water related research, development and innovation (RDI) activities while avoiding overlaps with ongoing actions co-funded by the European Commission and/or the Member States; • Improving the implementation of research and innovation programmes in these fields through exchange of good practices; • Contributing to the implementation of EU Water policies, the UN Sustainable Development Goals (SDGs), in particular SDG 6 and SDG 13, as well as the conclusions of the COP21 Agreement; and • Seeking synergies with international research programmes beyond Europe.

Keywords: resource efficiency,socio economic approach,water reuse
Local hyperthermia cancer treatment studies using a new temperature-imaging-hyperthermia-microscopy instrument (HYPTEMPCELL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-09-01
End date: 2020-11-01
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

The scientific aim of the project is to explore a new concept of magnetic hyperthermia treatment for cancer that gets closer to the ideal non-invasiveness & no-secondary-effects kind of treatment to become a primary choice for cancer therapy. Instead of the typical approach of massive tumor heating, this project takes the alternative route of local intracellular heating inducing cell apoptosis. For this purpose, the project will develop a new instrument for temperature_imaging-magnetic_induction_heating&microscopy. The temperature imaging system is a complete novelty and it is based on the use of molecular luminescent temperature probes embedded in magnetic and non-magnetic nanoparticles. The probe’s emission microscope image is transformed into high-resolution temperature images. This will be used to model the heat transfer processes inside a cell. Then, the effect of local magnetic heating on cell apoptosis processes will be studied, and the potential of this technique in cancer therapy will be evaluated. The researcher will contribute to the hosting group with his previous experience on synthesis, characterization and physical properties of luminescent, plasmonic and magnetic nanoparticles, and he will benefit with a more application-oriented research experience in the biomedical field, and will develop skills in new scientific areas, especially high-resolution luminescence thermometry, that will help him to set his personal research interests and career. He will also get clinical experience from contact with hospital oncologists. The researcher will be included in an interdisciplinary group with international connections that will widen his knowledge and contacts scope of his scientific career. He will also gain experience in other transversal skills, as he will be directly involved in the managing the project, student supervision, networking, dissemination and communication activities.

Keywords: nanobiomedicine,magnetic hyperthermia therapy,cancer therapy