Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
New light on the gamma-ray sky: unveiling cosmic-ray accelerators in the Milky Way and their relation to pulsar wind nebulae (P-WIND)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Universe sciences
Countries involved: France
Call:  (ERC-2010-StG_20091028, 2010)
Start date: 2011-01-01
End date: 2013-12-31
Duration (months): 36.0
Total project cost (EUR): 592680.0
EU funding (EUR): 592680.0
Participants: 1
Project status: CLOSED

Gamma-ray Astronomy pinpoints celestial high energy particle accelerators and may reveal the origin of the cosmic-rays, a century after their discovery. Now is a time of extraordinary opportunity. Cherenkov telescopes have opened up a new domain and more than 70 very-high energy gamma-ray sources have been detected above 100 GeV, especially by the European experiments H.E.S.S. and MAGIC. NASA's Fermi Large Area Telescope, devoted to the study of the gamma-ray sky between 20 MeV and 300 GeV, was launched in June 2008 and has published the positions of 1500 previously unknown gamma-ray sources spread across the sky. However, among all the sources detected by satellite and Cherenkov telescopes, hundreds of Galactic gamma-ray sources have no obvious counterpart at optical, radio, or X-ray wavelengths. What are these sources ? What role do they play in the Galaxy's energy budget ? Many of them must be pulsars or nebulae powered by pulsars. In this project, I propose to use my expertise in both TeV and GeV gamma-ray analysis together with the excellent links of our team with radio observatories to identify the nature of these sources, focusing on pulsars and pulsar wind nebulae as primary candidates. I further propose to use the theoretical models of these cosmic accelerators that I have developed in the past both to enhance the search, and to interpret the results. The range of competences required for the proposed research project is very large and difficult to gather in one single team: pulsar timing, experience with data analysis of extended sources and theoretical know-how in pulsar wind nebulae and high energy phenomena. The P-WIND team would therefore be unique in gamma-ray Astronomy.

Keywords: cosmic-rays,gamma-rays,fermi,hess,pulsar wind nebulae
Cryptography and Complexity (CAC)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Computer science and informatics
Countries involved: Israel
Call:  (ERC-2010-StG_20091028, 2010)
Start date: 2010-12-01
End date: 2015-11-30
Duration (months): 60.0
Total project cost (EUR): 1459703.0
EU funding (EUR): 1459703.0
Participants: 1
Project status: CLOSED

Modern cryptography has deeply rooted connections with computational complexity theory and other areas of computer science. This proposal suggests to explore several {\em new connections} between questions in cryptography and questions from other domains, including computational complexity, coding theory, and even the natural sciences. The project is expected to broaden the impact of ideas from cryptography on other domains, and on the other hand to benefit cryptography by applying tools from other domains towards better solutions for central problems in cryptography.

Keywords: theory of cryptography,complexity theory
Games and Automata for Logic Extensions (GALE)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Computer science and informatics
Countries involved: France
Call:  (ERC-2010-StG_20091028, 2010)
Start date: 2011-01-01
End date: 2015-12-31
Duration (months): 60.0
Total project cost (EUR): 931760.0
EU funding (EUR): 931760.0
Participants: 1
Project status: CLOSED

This proposal aims at generalising the central decidability results of Büchi and Rabin to more general settings, and understanding the consequences of those extensions both at theoretical and applicative levels. The original results of Büchi and Rabin state the decidability of monadic second-order logic (monadic logic for short) over infinite words and trees respectively. Those results are of such importance that Rabin's theorem is also called the `Mother of all decidability results'. The primary goal of this project is to demonstrate that it is possible to go significantly beyond the expressiveness of monadic logic, while retaining similar decidability results. We are considering extensions in two distinct directions. The first consists of enriching the logic with the ability to speak in a weak form about set cardinality. The second direction is an extension of monadic logic by topological capabilities. Those two branches form the core of the proposal. The second aspect of this proposal is the study of the `applicability' of this theory. Three tasks are devoted to this. The first task is to precisely determine the cost of using the more complex techniques we will be developing rather than using the classical theory. The second task will be devoted to the description and the study of weaker formalisms allowing better complexities, namely corresponding temporal logics. Finally, the last task will be devoted to the study of related model checking problems. The result of the completion of this program would be twofold. At a theoretical level, new deep results would be obtained, and new techniques in automata, logic and games would be developed for solving them. At a more applicative level, this program would define and validate new directions of research in the domain of the verification of open systems and related problems.

Keywords: automata,logic,games,infinite words,infinite trees,temporal logics
Controlled quantum effects and spin technology - from non-equilibrium physics to functional magnetics (CONQUEST)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Condensed matter physics
Countries involved: Switzerland
Call:  (ERC-2010-StG_20091028, 2010)
Start date: 2011-04-01
End date: 2016-03-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: CLOSED

The technology of the 20th century was dominated by a single material class: The semiconductors, whose properties can be tuned between those of metals and insulators all of which describable by single-electron effects. In contrast, quantum magnets and strongly correlated electron systems offer a full palette of quantum mechanical many-electron states. CONQUEST aim to discover, understand and demonstrate control over such quantum states. A new experimental approach, building on established powerful laboratory and neutron scattering techniques combined with dynamical control-perturbations, will be developed to study correlated quantum effects in magnetic materials. The immediate goal is to open a new field of non-equilibrium and time dependent studies in solid state physics. The long-term vision is that the approach might nurture the materials of the 21st century.

Keywords: quantum physics,quantum phase transitions,pump-probe
Solar cells at the nanoscale: imaging active photoelectrodes in the transmission electron microscope. (PHOTO-EM)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Physical and Analytical Chemical sciences
Countries involved: United Kingdom
Call:  (ERC-2010-StG_20091028, 2010)
Start date: 2010-12-01
End date: 2015-11-30
Duration (months): 60.0
Total project cost (EUR): 1381541.0
EU funding (EUR): 1381541.0
Participants: 1
Project status: CLOSED

The exploitation of renewable sources of energy is one of the biggest challenges of our time, with wide ranging implications in both Science and Society. The new generation of dye-sensitized solar cells and hybrid polymer-inorganic solar cells represents one of the most exciting developments in this field. These promising devices based on photoactive nanomaterials can be produced at low cost, but they have an overall power conversion efficiency of 10-12%, attributed to short charge carrier recombination times and diffusion lengths. If we hope to improve this performance we must learn how the solar cells behave at the nanoscale, under realistic working conditions. To achieve this I propose to study photovoltaic materials in the transmission electron microscope, under photon irradiation. The three main areas to pursue are: a) In situ illumination technique development, b) Study of physical properties of solar cells, c) Theoretical interpretation of the spectroscopy results. The work plan of this ERC project will follow different strands in parallel, so that we can explore this novel field more efficiently. Our in situ illumination technique will be exported to a new monochromated and aberration corrected transmission electron microscope with very high spatial and energy resolution. The ultimate challenge is to provide maps of the electronic properties and photovoltaic behaviour of a solar cell, in particular to evaluate –on the atomic level- the effect of grain boundaries and surfaces on the performance of the device. We will study both dye-sensitized and bulk heterojunction solar cells, starting from the individual nanostructured components, with the aim of producing working cross-section devices to be mounted and operated inside the electron microscope. Efficient data processing and theoretical interpretation of the microscopy results will be essential to the success of this process, so we will build capabilities in these areas to support and guide the experimental work. The team I want to lead in this scientific mission is ideally composed of a postdoctoral research assistant and two PhD students. The postdoc will take care of technique development and theoretical aspects, while the students will concentrate on the study of materials and devices.

Keywords: pe4_18 photochemistry
Innovative anti-influenza drugs excluding viral escape (ANTIFLU)

Framework: FP7 — Cooperation
Programme: Health
Destination: Translating research for human health
Action type: Collaborative project
Countries involved: Germany,Hungary,Denmark,Germany,France,Czechia,United Kingdom,Israel,Germany,Denmark
Call:  (FP7-INFLUENZA-2010, 2010)
Start date: 2011-06-01
End date: 2016-11-30
Duration (months): 66.0
Total project cost (EUR): 7821685.4
EU funding (EUR): 5999998.0
Participants: 11
Project status: CLOSED

ANTIFLU is to develop innovative drugs against influenza virus infections based on a novel concept that precludes the development of viral resistance and ensures efficacy against upcoming pandemic influenza strains. Viral replication is known to depend on multiple host factors. Whilst traditional anti-influenza treatments usually target viral factors, ANTIFLU will aim at drugs interfering with host-response pathways. The concept of drugs targeting human factors, established in treatment of other diseases, has yet not been sufficiently explored for treatment of viral infections, although it bears compelling advantages over conventional antiviral therapies: (i) the avoidance of viral escape mutants and (ii) the broad coverage against unprecedented viral variants. ANTIFLU aims to fully exploit this potent approach to fill critical gaps in our current treatment and prevention options against seasonal and pandemic influenza virus infections. By building upon an existing panel of potent human targets and firm knowledge derived from FP6 project RIGHT, an interdisciplinary consortium will pursue the identification and validation of small molecule ligands and inhibitory RNA molecules effective against influenza infection. Promising modulators will form the basis to generate lead molecules that will be further refined to yield clinically applicable therapeutics. Initial preclinical studies will aim at providing proof of concept in animal models, safety and toxicology profiles. They will allow initiating complete clinical trials immediately after the phase of FP7 support, thanks to the commitment already taken by investors from the private sector. The consortium includes several SMEs, internationally renowned research groups and clinical institutions with extensive experience in anti-influenza treatment and clinical trials. An already agreed common exploitation model will provide a smooth route to market and optimal use of the project results.

Keywords: influenza therapy,host factors,virus replication,small molecule inhibitors,sirna,clinical trial
European Surveillance Network for Influenza in Pigs 3 (ESNIP 3)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Coordination and support actions
Countries involved: United Kingdom,Belgium,France,Italy,Denmark,Poland,Germany,Finland,Hungary,Netherlands,Greece,United Kingdom,United Kingdom,Germany,Italy,United States,China,France,United Kingdom,Spain,Israel,Spain,United Kingdom
Call:  (FP7-INFLUENZA-2010, 2010)
Start date: 2010-11-01
End date: 2013-10-31
Duration (months): 36.0
Total project cost (EUR): 1205843.9
EU funding (EUR): 999500.0
Participants: 24
Project status: CLOSED

This “European surveillance network for influenza in pigs (ESNIP) 3” will maintain and expand surveillance networks established during previous EC concerted actions (ESNIP 1, QLK2-CT-2000-01636; ESNIP 2, SSPE-022749). Three work packages (WP 2, 3, 4) aim to increase the knowledge of the epidemiology and evolution of swine influenza (SI) virus (SIV) in European pigs through organised field surveillance programmes (WP2). Virus strains detected in these programmes will be subjected to detailed characterisation both antigenically (WP3) and genetically (WP4) using standardised methodology. Specifically this will involve timely information on genomic data and generation of antigenic maps using the latest technology. These analyses will provide significant and timely added value to knowledge of SIV. A strong focus will be monitoring spread and independent evolution of pandemic H1N1 2009 virus in pigs. All these data will in turn be used to improve the diagnosis of SI by updating the reagents used in the recommended techniques (WP2). The virus bank and electronic database that were established during ESNIPs 1 and 2 will also be expanded and formally curated with relevant SIV isolates and information for global dissemination within and outwith the consortium (WP5). ESNIP 3 represents the only organised surveillance network for influenza in pigs and seeks to strengthen formal interactions with human and avian surveillance networks previously established in ESNIP 2. A timely and transparent interaction with these networks will be a key output. These approaches are entirely consistent with improved pandemic preparedness and planning for human influenza whilst providing an evidence base for decisions in relation to veterinary health. The project consortium consists of 24 participants, which contribute a blend of different specialism’s and skills ensuring multi-disciplinary cutting-edge outputs. The vast majority of the partners are actively working with SIV including in a field setting. Twenty-one participants are from 11 EU member states, seven of which were actively involved in ESNIP 2. Co-operation with partners in China and North America will continue to promote a greater understanding of the epidemiology of SIVs at a global level.

Keywords: influenza network swine surveillance
Development of novel antiviral drugs against Influenza (FLUCURE)

Framework: FP7 — Cooperation
Programme: Health
Destination: Translating research for human health
Action type: Collaborative project
Countries involved: Sweden,Germany,Bulgaria,Netherlands,Lithuania,Italy,Sweden,Switzerland,Germany
Call:  (FP7-INFLUENZA-2010, 2010)
Start date: 2010-10-01
End date: 2014-09-30
Duration (months): 48.0
Total project cost (EUR): 7822101.0
EU funding (EUR): 5982600.0
Participants: 10
Project status: CLOSED

Influenza viruses cause a highly contagious respiratory disease in both humans and animals. Typically, influenza spreads worldwide in seasonal epidemics resulting in an estimated 3 to 5 million cases of severe illness and 250,000 to 500,000 deaths annually. In addition to these seasonal epidemics there have been several pandemics since the early 1900’s, where highly virulent strains emerged, the most devastating being the ‘Spanish Flu’ of 1918, which caused 20-40 million deaths globally. Vaccination is currently the primary means of controlling the spread of influenza virus infections but due to the virus’s notorious ability to mutate, new vaccines must be developed each year. There are a few antiviral drugs that are currently on the market; however, their therapeutic potential is restricted through rapid appearance of drug-resistant viruses during treatment. Thus, the need for novel effective drugs against influenza is evident. The FLUCURE project aims at developing innovative, first-in-class therapeutics against influenza by targeting the viral ribonucleoprotein complex, which is replication core of the virion and a major contributor to viral virulence. The high level of conservation combined with slow mutation rates of the ribonucleoprotein complex should result in therapeutics with broad viral strain specificity associated with a reduced risk for developing resistance. FLUCURE builds further on two successful EU-FP7 drug discovery projects, FLUINHIBIT and FluDrugStrategy, both targeting specific but different protein-protein interactions of the viral ribonucleoprotein complex with small molecule inhibitors. A consortium of 10 partners with the required complementary skills will progress the lead candidates from these two projects synergistically through lead optimization and preclinical development phases, with the final objective to deliver one or more drug candidates suitable for entering clinical development within 4 years.

Keywords: influenza,antiviral,drug development
Hierarchical and Adaptive smaRt COmponents for precision production systems application (HARCO)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: New production
Action type: Collaborative project
Countries involved: Italy,Italy,Spain,Germany,Belgium,United Kingdom,Israel
Call:  (FP7-2010-NMP-ICT-FoF, 2010)
Start date: 2010-07-01
End date: 2013-06-30
Duration (months): 36.0
Total project cost (EUR): 5406108.0
EU funding (EUR): 3899996.0
Participants: 10
Project status: CLOSED

The primary goal of HARCO project is to achieve cost-effective structural solutions consisting of a new class of Smart Components (belonging to machine tools applications) based on plug-and-produce “Modular Adaptronic devices” which integrate smart and multifunctional actuators/sensors capable of performing a wide array of multiple functions, ranging from high and adaptable damping and stiffness characteristics to more demanding new requirements, such as active structural measurement and control function to achieve extremely high dynamic/thermal stability required in fast and precision machining. The approach followed by HARCO is the hierarchical combination of lower level units (named here “Functional Bricks” to generate higher level modules (named here “Adaptronic Modules”) which in turn are used and integrated into machine parts to generate the master component (named “Adaptive Smart Components”). Then the basic idea is to design and develop a sort of “fractal” and “hierarchical” elements (not only mechanical hardware but also controllers and software) that can be easily put together (plugged-in) to form/produce higher level modules/components (modules that build modules!) for active vibration control, thermal compensation and adaptive fixturing in precision machine tools applications.

Keywords: adaptive control,plug and produce modules and components,hierarchical control,active damping,vibration suppression,energy harvesting
Model-based Analysis & Engineering of Novel Architectures for Dependable Electric Vehicles (MAENAD)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Contribution of the ICT Theme to Public-Private Partnerships for R&D in the European Economic Recovery Plan
Action type: Collaborative project
Countries involved: Sweden,Italy,Germany,France,Sweden,Germany,United Kingdom,Finland
Call:  (FP7-2010-ICT-GC, 2010)
Start date: 2010-09-01
End date: 2014-02-28
Duration (months): 42.0
Total project cost (EUR): 4022326.0
EU funding (EUR): 2467593.0
Participants: 13
Project status: CLOSED

Fully Electric Vehicles (FEV) promise clear benefits to society. At the same time, the engineering of FEV introduces significant new challenges. FEV will be highly integrated and increasingly dependent on software and electronics. FEV systems will have more authority, share common components and rely less on mechanical backups. New complex power management and optimization algorithms are needed to ensure high performance, range of travel and low energy consumption. We argue that the challenges faced in the engineering of FEV are already partly met by EAST-ADL, an emerging automotive architecture description language (ADL) compliant with AUTOSAR, and that EAST-ADL is the appropriate vehicle for fully meeting these challenges. MAENAD will extend EAST-ADL with advanced capabilities to facilitate development of dependable, efficient and affordable FEV. The project will achieve language and tool support for: - Support for the ISO 26262 automotive safety standard, including a novel approach for automatic allocation of safety requirements to components of an evolving architecture - Effective model-based prediction of quality attributes of FEV such as the dependability and performance, via use of advanced, scalable, automated techniques. -Automated exploration of potentially huge design spaces to achieve better or optimal trade-offs among dependability, performance and cost. The scope of the modeling language and analysis focuses on the system structure and dynamics, in terms of physical, computational and communication components, their composition and interactions. To achieve those objectives, MAENAD will exploit and further develop the present state of the art in model-based design, assessment and optimization technologies. In addition, MAENAD will propose an overall design methodology for FEV and evaluate its application via a realistic case study on an innovative FEV system which represents a current design challenge.

Keywords: model based development,safety assessment,embedded architecture,electrical vehicles