Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Dynamic Activatable Fluorophores (DYNAFLUORS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-06-01
End date: 2024-12-31
Duration (months): 79.0
Total project cost (EUR): 1986650.0
EU funding (EUR): 1986650.0
Participants: 1
Project status: SIGNED

In DYNAFLUORS I will develop the first chemical toolbox for imaging in real time the activity of immune cells in tumours. Although the management of cancer has improved over the years, the cure rates for patients with metastasis and advanced tumours remain low due to lack of appropriate therapies. Recent studies suggest that drugs empowering host immune cells (i.e. immunotherapies) are promising approaches for intractable tumours. However, there are no tools to visualise and understand how host immune cells stop cancer progression in vivo. This important unmet challenge drives the ambitious targets of this proposal. Over the past 10 years, I have pioneered the development of chemical fluorophores that allow unparalleled analysis of biological systems. In this project, I will implement an innovative approach to unify cutting-edge methodologies in chemistry and biology and develop Dynamic Activatable Fluorophores (DYNAFLUORS) as a chemical toolbox with enhanced imaging capabilities over current technologies. The cross-disciplinary and ambitious nature of this project will open multiple avenues for broad impact in many areas of chemistry as well as in basic biology, imaging and medicine. DYNAFLUORS will allow us to image, from the molecular level to human tissue, the activity of immune cells in tumours and the response to therapy in real time. This ground-breaking chemical platform will represent a step forward in the forefront of chemical imaging and will create new opportunities in the personalised management of cancer. In the long term, DYNAFLUORS will become a transformative toolbox for monitoring disease in humans. The integration of functional fluorophores into imaging technologies to perform ‘optical biopsies’ in vivo and to create patient-specific drug-response assays has the potential to revolutionise the diagnosis, stratification and personalised treatment of disease.

Keywords: fluorescent probes,optical imaging,peptide chemistry,cancer immunology
Ku-Band Satellite Receiver (KuRx)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: SME instrument
Countries involved: United Kingdom
Call: Engaging SMEs in space research and development (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-06-01
End date: 2017-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The objective of the feasibility study is to explore and assess the technical feasibility, and the commercial potential of the company's, award-winning and highly-disruptive invention: a novel Ku-band receiver for space applications. For the first time, the innovation will allow satellites to directly process signals up to 18 GHz completely removing the need for any traditional, analogue, RF down-conversion. This represents a profound advance for electronic engineering and satellite communications! The expected outcome is that the company will have elaborated a commercial strategy for formally productising and bringing to market its innovation, e.g. assembly, test, branding, sales and marketing. The proposed innovation solves the following problems: Today, the satellite industry is handicapped by the inflexibility, complexity, power consumption and cost of traditional, analogue RF down-conversion, with each stage costing €160k. For key European suppliers of satellites, conventional receiver designs are adding over €8M to the cost of each European payload. The current approach to satellite design requires the design of existing receiver technology to be changed for almost every new mission adding unnecessary, non-recurring re-design and re-qualification costs and effort to key European programs. These disadvantages severely handicap European space companies when competing for global satellite tenders. Today, the majority of satellite communication occurs at L/S & C-band, however, these frequencies have become congested and both the space industry, European governments and European space agencies are looking to Ku-band to provide operators the bandwidths needed to deliver tomorrow's, space-enabled economy for everyone. Spacecraft operators are constantly complaining that the cost to develop satellites is prohibitively expensive, delivery takes too long and never right-first-time.

Keywords: ku band,satellite transponder,satellite receiver
RObotics for MIcrofarms (ROMI)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Spain,France,France,France,France,Netherlands
Call: Robotics Advances for Precision Farming (H2020-SFS-2017-1, 2017)
Start date: 2017-11-01
End date: 2022-07-31
Duration (months): 57.0
Total project cost (EUR): 3868186.25
EU funding (EUR): 3868186.25
Participants: 11
Project status: SIGNED

All over Europe, young farmers are starting small market farms. These farms can be found both in rural, peri-urban and urban areas. They grow a large variety of crops (up to 100 different varieties of vegetables per year) on small surfaces (0.01 to 5 ha) using organic farming practices. These farms have proven to be highly productive, sustainable and economically viable. But, a lot of work is done manually, resulting in physically challenging work conditions. ROMI will develop an open and lightweight robotics platform for these microfarms. We will assist these farms in weed reduction and crop monitoring. This will reduce manual labour and increase the productivity. Thanks to ROMI’s weeding robot, farmers will save 25% of their time. This land robot will also acquire detailed information on sample plants and will be coupled with a drone that acquires more global information at crop level. Together, they will produce an integrated, multi-scale picture of the crop development that will help the farmer monitor the crops to increase efficient harvesting. For this, ROMI will have to adapt and extend state-of-the-art land-based and air-borne monitoring tools to handle small fields with complex layouts and mixed crops. To achieve this, we will: (i) develop and bring to the market an affordable, multi-purpose, land-based robot, (ii) develop a weeding app for this robot that is adapted for organic microfarms, (iii) apply advanced 3D plant analysis and modelling techniques to in-field data acquisition, (iv) integrate these analysis techniques in the robot for detailed plant monitoring, (iv) integrate these techniques also in the aerial drone N-E-R-O for multi-scale crop monitoring, (v) extend the robot with novel, adaptive learning techniques to improve sensorimotor control of the plant monitoring app, and (vii) test the effectiveness of our solution in real-world field conditions. A spin-off will be created to bring the robot and the drone to the market of micro-farms.

Keywords: agroecology,microfarm,precision weeding,phenotyping,crop monitoring,plant modelling,adaptive systems,drone,photogrammetry,3d imaging,computer vision,field studies
WArm Climate Stability of the West Antarctic ice sheet in the last INterglacial (WACSWAIN) (WACSWAIN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: United Kingdom,United Kingdom
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-08-01
End date: 2023-01-31
Duration (months): 66.0
Total project cost (EUR): 2817554.0
EU funding (EUR): 1302035.25
Participants: 3
Project status: CLOSED

Recent papers predict the loss of most of the West Antarctic Ice Sheet (WAIS) by 2500 if CO2 emissions and rising global temperatures are not controlled. It is critical to test whether the models making such worrying predictions are realistic. I will do this by obtaining new data from the last interglacial (LIG, 130,000-115,000 years ago) to assess the response of the WAIS to comparable warmth. During the LIG, sea level reached 6-9 m higher than today. It is inferred that Antarctic ice sheets contributed several metres of sea level rise, under a climate similar to the one we could be committing ourselves to in the next few centuries. Most authors assume that the lost ice came mainly from the WAIS. Models that predict large ice loss in the future also produce a very significant retreat of the WAIS and loss of the Ross and Ronne ice shelves under LIG conditions. Were the WAIS and Ronne Ice Shelf significantly smaller in the LIG? If so, what was the time course of their retreat and regrowth? This project will remedy the surprising lack of direct evidence about these questions. I will examine data from ice cores that reach the LIG, drilled on the periphery of the WAIS. I will include retrieval of one new strategically-placed bedrock core, and obtain an isotope profile that will test the potential of another site. The loss of much of the WAIS would have several effects on peripheral ice caps: glacio-isostatic (GI) uplift and a change in atmospheric circulation would cause a recognisable spatial and temporal pattern of symptoms. The retreat of the Ronne Ice Shelf would leave a clear signature in marine aerosol concentrations in the ice. By examining changes in water isotopes, sea salt, air content and other proxies in all the cores, in comparison with different model outputs, I will estimate the timing and extent of WAIS retreat and regrowth during the LIG. This will support or question the use of sensitive models to predict future change in the WAIS.

Keywords: ice cores,antarctica
Social Innovation Matched Crowdfunding (SIM Crowd) (SIM Crowd)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Austria
Call: Supporting experimentation in innovation agencies (H2020-INNOSUP-2018-06-two-stage, 2018)
Start date: 2019-09-02
End date: 2022-01-01
Duration (months): 28.0
Total project cost (EUR): 287500.0
EU funding (EUR): 287500.0
Participants: 1
Project status: CLOSED

The main objective of the proposed project is to conduct an experiment and test the effects of a “seal” (“funded by FFG”) and information about matched funding provided by a public funding organisation (FFG) on the funding decision of the audience on crowdfunding platforms. A randomised controlled trial (RCT) will be conducted within the existing funding scheme “Impact Innovation” of the Austrian Research Promotion Agency/FFG. FFG first launched a pilot scheme for a new programme called “Impact Innovation” in 2017. A second call with improvements in communication and evaluation criteria was carried out until autumn 2018. About 30% of proposals in these two pilot schemes addressed problems or solutions that were classified as “social innovation”. A recurring pattern in these proposals was lack of or failure to provide sufficient funding to cover the total cost of the project (FFG funds up to 50% of total project cost). In addition to this FFG received feedback from the community of social innovators that a significant number of ideas was not even submitted because the potential applicants could not generate or demonstrate the necessary funds to completely fund the project (100%). FFG therefore wants to test whether and how providing information on available public funding for social innovation projects will increase (or decrease) the chances to attract funding for the remaining 50% of project cost. This test will be run on a crowdfunding plattform for selected projects and – if the results are positive - increase the total amount of funding for successful social innovation projects and provide evidence for leverage effects of matched crowdfunding.

Keywords: crowdfunding,social innovation,experimentation,randomised controlled trial rct
LaserTrain (LT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Netherlands
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-12-01
End date: 2020-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Anyone who travels by train is familiar with delays. Track contamination such as rust, oil and most notoriously autumn leaves cause the tracks to become slippery. Research shows that this leads to 75% lower traction and as a result to severe safety issues from the reduced braking ability. Low traction also leads to slipping and sliding wheels creating ‘flat spots’ and damages wheel and track. Launching customer MTA Long Island Rail Road estimates the cost of wheel repairs at €3.000 each and that for a total of 3.307 wheels in 2017. As for safety issues, in 2017 in the UK 295 trains failed to stop at stations or red lights. The UK infrastructure manager Network Rail shows that slippery tracks cost them an annual €320 million, showing that there is need for a working solution. Laser Tribology B.V. (LPS) has developed the solution: the LaserTrain. Using high-powered laser pulses the slippery contamination layer is vaporized from the track, without heating up or damaging the track. The LaserTrain is a separate wagon that can be pulled by locomotives in any operator’s network. A few dedicated cleaning LaserTrains clean the network between September and March when the contamination layers hinder operations. After three years of R&D, a full in-house simulation and a prototype on live track the system is now ready for a debut in Europe. The system is fully standalone, requires only energy and cleans at 80 km/h, so it blows away the competition in every aspect. In Europe there is a long list of prospects following our development closely, such as Network Rail (UK), Banedanmark (DK), Dutch Railways (NL), Deutsche Bahn (DE) and PKP (PL). To meet their demand, engineering on an 80 km/h LaserTrain has finished. Now it’s time to protect the most vital parts of the IP and make it a huge commercial success in Europe. This feasibility study helps do just that. Firstly we look at how bank funding allows us to pre-finance multiple orders. Secondly we improve our knowledge protect

Keywords: train,laser,optics,software,slippery track problem,tribology,physics
Smart Mattress for Babies (SensoDream)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Sleeping, the worry that is even greater than baby feeding and recovery from birth. Frequently, new parents have to wake up during the night and go to the cradle reducing drastically their necessary sleep time. This is not an anxious behaviour and is fully justified since i.e. a good sleep is essential for a proper brain development and babies with more efficient night time sleep had higher cognitive scores. Besides, babies that sleep better have an “easier” temperament, being more sociable and approachable. Moreover, several studies have shown that babies that get less sleep gain more fat as infants and are at higher risk of being overweight. On the other hand, sleep is also fundamental for parents. When infants don’t sleep, their parents do not either and mothers of babies with sleep problems are at higher risk of postpartum depression. New technologies are required to both provide a comprehensive online monitoring of the baby including warning and alerts and perform a deep and reliable analysis of his/her sleep data aiming to find if there is a poor baby sleep and find the real causes for it. These technologies are needed to guarantee babies and parents’ health, set up healthy sleeping routines and provide peace of mind to parents. SensoDream is an Ecus® mattress specially designed for the baby comfort and health that also incorporates numerous different types of sensors (humidity, pressure, temperature, etc.) and a data processing unit (electronic hub). It also includes a smart app for baby sleep monitoring and analysis. SensoDream monitors the baby sleep, presents warnings and alarms (i.e., the child is excessively wrapped, wet diaper etc.), performs data analysis and detects poor sleep and its causes providing recommendations.

Keywords: mattress,baby,sleep,sleep quality,new parents,sensors,sleep patterns,sleep monitoring and analysis
Demonstration of innovative integrated biomass logistics centres for the Agro-industry sector in Europe (AGROinLOG)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable and competitive bio-based industries and supporting the development of a European bio-economy
Action type: Innovation actions
Countries involved: Ukraine,Spain,Italy,Spain,Serbia,Belgium,Greece,Sweden,Greece,Greece,Sweden,Sweden,Sweden,Netherlands
Call: Demonstration of integrated logistics centres for food and non-food applications (H2020-RUR-2016-1, 2016)
Start date: 2016-11-01
End date: 2020-07-31
Duration (months): 45.0
Total project cost (EUR): 6385661.25
EU funding (EUR): 5935714.89
Participants: 17
Project status: CLOSED

The main goal of AGROinLOG is the demonstration of Integrated Biomass Logistic Centres (IBLC) for food and non-food products, evaluating their technical, environmental and economic feasibility. The project is based on three agro-industries in the fodder (Spain), olive oil production (Greece) and cereal processing (Sweden) sectors that are willing to deploy new business lines in their facilities to open new markets in bio-commodities (energy, transport and manufacturing purposes) and intermediate bio-products (transport and biochemicals). These sectors represent over 10% turnover of agro-food industries and 30% of those with inherent synergies to integrate food and non-food business taking advantage of their existing equipment, seasonality and established food logistics. The synergies of applying IBLCs business in existing agro-industries can have a positive impact over 18% in final product price, giving a clear competitive strength to a wide segment of agro-industries, which can exploit this privileged situation compared to a new biomass supply business built from scratch. The project is built on these agro-industries that will achieve a TRL7-8 in their facilities, guaranteeing operation under real conditions and with big amounts of production compared to the current activity, ensuring proximity to real market at the end of the project. Main challenges are based on being able to integrate logistics, harvesting and equipment in food and non-food applications, where the project is focused; ensuring marketability of the final bio-commodities. Besides, AGROinLOG will apply a multi-actor approach to attain experiences and knowledge of the sectors and agro-industries, enhancing the accuracy of the business models and developing effective and friendly guidelines of best practices to replicate and spread IBLC concept in Europe. This project will contribute towards employment stability –seasonality avoidance-, rural development and bio-economy goals.

Keywords: logistic centre,bio commodity,food and non food,agricultural,multi actor approach,bioproduct,rural development
The Dawn of Organic Chemistry (DOC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: France,France
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-10-01
End date: 2022-09-30
Duration (months): 60.0
Total project cost (EUR): 2454367.5
EU funding (EUR): 2454367.5
Participants: 3
Project status: CLOSED

Terrestrial life is based on organic chemistry, on the complex combination of relatively small molecules containing less than 50 atoms of carbon and other elements in smaller quantities. Some of these bricks, notably amino acids, are found in meteoritic and cometary material, a fact (among others) which led the Nobel laureate C. de Duve to conclude that “the seeds of life are universal” and “life is an obligatory manifestation of matter, written into the fabric of the Universe”. The objective of the DOC project is to understand the dawn of organic chemistry, namely the start of organic chemistry in systems similar to the progenitor of the Solar System, with the ultimate goal to understand how organic chemistry builds up and evolves in these systems and, consequently, to understand how universal the chemical seeds of life are. To achieve this objective, I propose to build a reliable theory for the organic chemistry in nascent Solar type systems, by combining in a tightly coordinated way new ground-breaking astronomical observations, quantum chemistry computations, astrochemical/chemi-physical models and sophisticated analysis tools. The DOC project is based on (i) a mine of first-class data from already awarded Large Programs at IRAM and from a plethora of smaller proposals at IRAM, ALMA and APEX, (ii) new state-of-the-art quantum chemistry computations to understand astrochemistry reactions at the molecular level, and (iii) models and tools to fully exploit the new data and computations. My ambition is to provide a reliable theory not only for the astrochemical and the star and planet formation communities, but also for the extragalactic one. Indeed, the new highly sensitive spectral observations from facilities like IRAM, ALMA and, in the future, SKA will inevitably contain lines from many organic molecules. DOC ambition is to ultimately allow us to understand how organic chemistry unfolds in the Universe.