Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
IP4OS Unpacking the possibilities of Intellectual Properties for Open Science (IP4OS)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Reforming and enhancing the European R&I System
Destination: Reforming and enhancing the European R&I System
Action type: Coordination and support actions
Countries involved: Germany,Sweden,Netherlands,Spain,Bulgaria,Croatia
Call: Capacity building on Intellectual Property (IP) management to support open science (HORIZON-WIDERA-2024-ERA-01, 2024)
Start date: 2025-01-01
End date: 2026-12-31
Duration (months): 24.0
Total project cost (EUR): 1920891.25
EU funding (EUR): 1920891.25
Participants: 8
Project status: SIGNED

The main aim of IP4OS is social innovation: to empower multi-professional teams and their organisations in each of the 27 European countries with knowledge, skills, awareness and advocacy to boost the valorisation of scientific knowledge in the ERA to a new level by promoting a concerted approach to agile IP management and OS practices. IP4OS will (1) describe a concerted IP-OS approach in the Synergy Framework with best practices on agile IP management to support OS practices, (2) inform the Community of practice about the Synergy Framework with a Role-Model Campaign using advocates, facts and figures, (3) train multi-professionals in agile IP Management with the Synergy Core Curriculum (4) empower multi-professional teams in HEIs and RPOs to use agile IP management to support OS. IP4OS will publish and disseminate an open-access and sound Synergy Framework, providing recommendations for best practices. The project raises 50% more awareness in the Community of Practice by informing about advocates, facts and figures on IP tools that support OS practices. Furthermore, IP4OS will reach 300 trained professionals and additionally (at least) 27 multipliers for multi-professional teams from all European countries via several easy-to-use and sustainable educational resources using the Synergy Framework and the Synergy Core Curriculum. Furthermore, IP4OS will build a Community of Practice by interacting with the different stakeholders in IP and OS. In particular, training and empowerment tasks target 15 professions divided into (A) IP experts and intermediaries, (B) experts performing research, and (C) trainers teaching IP in/and research. With the consortium's extensive IP and OS knowledge, established training and campaign infrastructure, and exceptional expertise, IP4OS can achieve its ambitious objectives in 24 months.

Keywords: open science,intellectual property,intellectual assets,research,multiprofessional learning
Astro Dark Large & Small (AstroDarkLS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Switzerland,Italy
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-11-01
End date: 2029-10-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 2
Project status: SIGNED

The Standard Model (SM) of particle physics is a successful, extremely well-verified theory. Nevertheless, the SMappears far from being complete. There are still many theoretical and experimental open questions: the strong-CP problem, the origin of neutrino masses, the nature of dark energy and dark matter. The need for physics beyond the Standard Model (BSM) is undeniable, but the question The Standard Model (SM) of particle physics is a successful, extremely well-verified theory. Nevertheless, the SM appears far from being complete. There are still many theoretical and experimental open questions: the strong-CP problem, the origin of neutrino masses, the nature of dark energy and dark matter. The need for physics beyond the Standard Model (BSM) is undeniable, but the question is: how and where will we find it? The aim of the AstroDarkLS project is to try to discover or falsify important theoretical models of light particles, such as axions and dark photons, considering their impact in astrophysical and cosmological systems which were never considered in depth by the particle physics community. The project is organised around three main themes, spanning various length scales in the universe: the use of stars and astrophysical objects to look for new physics; the impact of motivated BSM models on star formation; the investigation of electromagnetic signals both from galaxies and the interstellar medium between them. For each theme groundbreaking objectives are identified, such as the first simulation of Supernovae radiative transport including axions, the first public code for star formation in the presence of light physics, the innovative use of line intensity mapping (LIM) to detect dark matter decay or annihilation into photons. All the objectives are located at the interface between particle physics, astrophysics and cosmology, building on the unique experience of the PI in these various disciplines and in perfect alignment with the European Commission vision.

Keywords: dark matter,axions,dark photons,stars and new physics,astroparticle physics
Using seed functional traits to understand and predict alpine plant responses to global climate change (SEEDTRAITS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Norway,United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 251578.56
EU funding (EUR): 251578.56
Participants: 2
Project status: SIGNED

To improve predictions of how plants may persist or disappear from ecosystems, we urgently need improved understanding of how climate change affects a critical and vulnerable plant life-history stage and transition–seeds and seed recruitment. Seed ecology is a growing discipline, yet it lacks some of the recent standardised methods and centralised resources of other plant sciences, such as the core databases and methodological handbooks that have spurred plant functional trait innovation since the early 2000s. Alpine areas can provide a glimpse of our future under climate change because they are warming faster than global averages and because alpine ecosystems are temperature-limited and hence more vulnerable to warming. Long-term warming experiments demonstrate that this vulnerability can alter vegetation structure, which in turn may change vegetation function, particularly carbon cycling. To predict which plants will persist, we need better data and frameworks for understanding how seeds and seed recruitment in the alpine respond to warmer climates. I will (1) publish a standardised handbook of core seed trait measurements, (2) collect new trait data from seed collections and harmonise existing datasets to form a publicly accessible alpine seed trait database, (3) establish a functional trait-based framework of seed ecology, and (4) experimentally test how seeds respond to warming as a demonstration of how these new resources can rapidly expand our understanding of climate change effects on seed ecology.

Keywords: functional traits,seeds,open science,database,methodology,climate change,alpine ecology,plant life history
SKILL PARTNERSHIPS FOR SUSTAINABLE AND JUST MIGRATION PATTERNS (SKILLS4JUSTICE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Social and Economic Transformations
Action type: Research and Innovation actions
Countries involved: Lithuania,Germany,Italy,Türkiye,Norway,Ethiopia,France,North Macedonia,Poland,Ukraine,United Kingdom
Call: Global Shortages and Skill Partnerships (HORIZON-CL2-2023-TRANSFORMATIONS-01, 2023)
Start date: 2023-11-01
End date: 2026-11-30
Duration (months): 37.0
Total project cost (EUR): 3047146.25
EU funding (EUR): 3047146.25
Participants: 13
Project status: SIGNED

This project aims to develop systemic analysis of skills shortages in the 5 EU countries (France, Germany, Italy, Poland, Lithuania) and 6 non- EU countries (Turkiye, UK, Norway, Noth Macedonia, Ukraine, Ethiopia) in the context of the global workforce migration by providing research-based evidence on the nature and development of skill shortages as well as on the potential of different skills partnerships to tackle these shortages in the countries of origin and destination of migrants. There are four main objectives of research (serving as a basis for the corresponding work-packages) which contain different sets of research questions and activities: 1. Designing of the shortage model for recruitment of skilled workers in the countries of destination (1st group), transition countries (2nd group) by referring to the agency of existing skill partnerships in these countries. 2. Evaluation of the labour market in analysing matching needs and shortages of skilled workforce in the countries of origin compared to the countries of destination and transition countries. 3. Surveying skilled migrant workers in the countries of destination and origin (returned migrants). This survey seeks to provide the perspective of migrants to the above discussed questions of research. 4. Analysis of conditions which influence positively or negatively local development processes vis-à-vis foreign upskilling and recruitment in the destination countries, as well as the conditions which lead to domestic institutions of the origin countries to capitalize on the positive effects of migration for skill development of their population. 5. Preparing a toolkit for implementation and development fo skill partnerships between the countries of origin and destination in order to enable and facilitate sustainable and fair investments in skills and dealing with the challenges of skill shortages and migration by preventing skill losses and brain drain.

Keywords: skill matching,skill mismatches,skill partnerships
Targeting tumour-host interactions in paediatric malignant gliomas to reinvigorate immunity and improve radio- and immunotherapy efficacy (HIT-GLIO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Cancer
Destination: Cancer
Action type: Research and Innovation actions
Countries involved: Poland,France,Netherlands,Germany,Israel,United Kingdom,Italy,Canada
Call: Addressing poorly-understood tumour-host interactions to enhance immune system-centred treatment and care interventions in childhood, adolescent, adult and elderly cancer patients. (HORIZON-MISS-2023-CANCER-01, 2023)
Start date: 2023-12-01
End date: 2027-11-30
Duration (months): 48.0
Total project cost (EUR): 9650975.0
EU funding (EUR): 9650975.0
Participants: 11
Project status: SIGNED

Paediatric high-grade gliomas (pHGGs) are malignant, deadly tumours developing in infants and children. Mutations in histone coding genes disturb epigenetic regulation and in cooperation with other oncogenes promote tumour initiation and progression. pHGGs are fast-growing and diffusive which makes them hard to remove or treat. Surgery (unattainable in midline brain regions) and radiotherapy (RT) remain the only option with transient benefits as median survival is 9-15 months. Those tumours are immunosuppressed, thus immunotherapy is ineffective. We propose that knowledge of tumour-host interactions in the tumour microenvironment (TME) would reveal novel targets allowing to find new ways to eradicate mutated tumour cells, improve efficacy of RT, and reinvigorate anti-tumour immunity. To achieve these ambitious goals we built up the international, multidisciplinary consortium HIT-GLIO. We will i) use latest single-cell technologies and multimodal imaging to characterise tumour-immune cell interactions in a large spectrum of pHGG patient samples; ii) create cellular and animal models of increasing complexity: human glioma-microglia co-cultures, DIPG-derived organoids complemented with iPSC-derived immune cells and syngeneic pHGG mouse models which would be platforms for mechanistic studies and drug screening; iii) evaluate hypoxia-inducible epigenetic inhibitors and blockers of tumour-host interactions to improve RT and immunotherapy responses; iv) generate nanocarriers functionalised to target immune cells and deliver drugs to the brain; v) develop more effective CAR-T cells that together with TME reprogramming and RT would boost anti-tumour immunity; vi) assess neurodevelopmental alterations and psychological consequences of disease and foster psychological approaches to increase quality-of-life of patients and caregivers. The expected outcomes of HIT-GLIO would ultimately pave ways to new clinical trials to improve the way pHGGs are treated. This action is part of the Cancer Mission cluster of projects on “Understanding (tumour-host interactions).

Keywords: paediatric high grade gliomas dipg immunotherapy immunosuppression car t cells hypoxia radiotherapy
AI-informed Holistic EVs integration Approaches for Distribution grids (AHEAD)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Italy,Denmark,Portugal,Norway,Finland,Albania,Austria,Slovenia,Belgium,United Kingdom
Call: System approach for grid planning and upgrade in support of a dominant electric mobility (vehicles and vessels) using AI tools (HORIZON-CL5-2023-D3-03, 2023)
Start date: 2024-06-01
End date: 2028-05-31
Duration (months): 48.0
Total project cost (EUR): 12845000.0
EU funding (EUR): 10997750.0
Participants: 28
Project status: SIGNED

The AHEAD (AI-informed Holistic Electric Vehicles Integration Approaches for Distribution Grids) project will create a simulation environment capable of predicting the most convenient location to place the electric vehicle (EV) charging stations and optimise both the usage of the power grid resources, and the charging stations located in urban and rural areas. This simulation environment will exploit the unique features of currently available AI models and include two layers: the spatial mapping one (placing the chargers where the people need them to be), and the power grid one (placing the chargers where the grid can support them). Innovative smart charging algorithms will be designed and tested in the model, to minimise the impact of EV charging pools on the network, and ensure the consumers have economic benefits. Moreover, these smart charging algorithms will be tested in three demonstration sites, dedicated to assessing the technical and economic feasibility of smart charging light and heavy-duty EVs, and boats. To this end, AHEAD gathered relevant partners from all the EV value-chain: technology providers who want to test their equipment in the real world, grid operators, who want to optimise the usage of the grid resources and mitigate the EV charging impact, and research institutions, who aim at advancing the knowledge on the topic and producing value for society. Particular attention is going to be placed on the user experience and cybersecurity part of the demonstrators, with specific partners who focus their efforts on understanding how to minimize the impact of smart charging on the user experience and on creating a model to represent cyber-attacks on the chargers to suggest efficient defensive mechanisms for system protection.

Keywords: planning of distribution grids,artificial intelligence,flexibility services,spatial mapping models,threat modelling
Premotor visual perception in the fovea and foveola (ActiveFovea)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,United States
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2029-08-31
Duration (months): 36.0
Total project cost (EUR): 401232.0
EU funding (EUR): 401232.0
Participants: 2
Project status: SIGNED

Human vision is sharpest in the central 5.5 degrees of the visual field (the fovea) and becomes increasingly blurry towards the periphery. In everyday situations, we frequently execute large-scale eye movements called saccades to inspect objects of interest with high-acuity foveal vision. Despite its crucial importance for human perception, foveal vision is surprisingly understudied, particularly in the actively moving observer. Perhaps most detrimental to its study is the simple assumption that foveal vision is saturated and uninfluenced by ongoing motor processes; much like the lens of a microscope, visual perception in the center of gaze is presumed to reflect the ground truth of our environment. Nonetheless, I have previously demonstrated that right before a saccadic eye movement, defining features of the eye movement target (such as its orientation content) are predictively enhanced in foveal vision, resulting in substantial modulations of visual perception in the area of highest acuity. ActiveFovea builds on these findings by combining several cutting-edge methodologies, namely human psychophysics, high-precision Dual-Purkinje-eyetracking, primate electrophysiology and eye-head-tracking in a 360° display environment, under a common aim: transforming our understanding of foveal vision from a passive recipient of high-acuity input to a dynamic and predictive component of active perception. In four work packages, and with the involvement of leading experts in the field, ActiveFovea will investigate the spatiotemporal and featural properties of premotor foveal perception in different species and across different body movement types. Ultimately, we hope to establish foveal vision as a research area well worth investigating and aim to provide a seminal knowledge base that will guide future studies for years to come.

Keywords: visual perception,active vision,eye movements,saccades,psychophysics,foveal vision,pre saccadic attention,predictive remapping
Delivering justice on a transnational scale in Europe. The Roman Rota and the enforcement of a legal culture of negotiation (c. 1560-1700). (ROTAROM17)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: France,Italy,Italy
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1808750.0
EU funding (EUR): 1808750.0
Participants: 3
Project status: SIGNED

ROTAROM17 aims to understand the Roman Rota as one of the essential tools of the Catholic Church’s transnational governance in early modern Europe. How did this Rome-based court of appeal, which judged in the pope’s name important civil disputes involving the clergy and members of the social elites, succeed in having its authority respected outside the pontifical state? Why did men and women from Spain, Portugal, or Poland expect to find in Rome a better justice, in spite of the long, cautious and costly Rotal procedure? On which grounds did challenges and criticisms of Rota’s jurisdiction have political significance? Our aim is to study this institution which remains poorly known for this period, but also to see law in action in the settling of disputes, as well as the way in which the court’s jurisprudence, used as a reference by legal experts and disseminated in libraries, contributed to the making of a legal culture founded on negotiation. The project’s second objective is to open a new research field on Europe’s oldest still-active tribunal and facilitate access to its massive and under-used documentation by producing essential research tolls and reference works, thus laying strong foundations for future developments of scholarship. ROTAROM17 brings together an international and multidisciplinary team (social, diplomatic, cultural and intellectual history, legal history) and foregrounds primary research, connecting the Rota’s archival funds with a large set of archival funds and libraries in Europe. By renewing approaches to the Roman Rota, its environment, personal, litigants, and jurisprudence, and by opening up access to hitherto untapped documentation, ROTAROM17 will make a major and original contribution to rethinking the structuring role of the law in European culture and offer new opportunities for historians to explore their local or national fields of research from multiple perspectives in a large set of countries.

Keywords: justice,rome,family,nobility,catholic church
Carbanions as Functional Groups and Building Blocks for Novel Reagents, Catalysts and Materials (CarbFunction)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-07-01
End date: 2028-06-30
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Carbanionic compounds such as organolithium or Grignard reagents are important organometallic reagents and commonly used in organic synthesis for difficult deprotonation or C-C bond formation reactions. Due to the strongly polarized metal carbon bond these reagents are usually highly reactive and sensitive towards air and moisture and thus must be handled under strictly anhydrous conditions. Owing to this intrinsic reactivity, carbanionic compounds are usually only prepared in situ and scarcely applied beyond their classical use as strong bases or alkylation reagents. Free carbanions without stabilizing metal-carbon inter¬action are usually even more reactive but can be isolated when being stabilized by electron withdrawing groups. These naked carbanions are isoelectronic to simple amines. Yet, whereas amines are applied in various fields of chemistry not only as bases but also as versatile building blocks and functional groups, applications of free carbanions are very limited. This project will change the perspective on carbanionic compounds. By careful molecular design the reactivity of carbanions will be controlled to enable their use as broadly applicable building blocks and functional groups. Experimental and computational methods will provide a fundamental understanding of the electronic structure and its influencing factors, thus allowing for a systematic use of the anionic nature and donor capacity of carbanions to reach properties and reactivities, which are not accessible via conventional strategies. Thus, we will provide a new toolbox for the design of smart anionic reagents and catalysts. The power of this concept will be demonstrated by applying carbanions in different research directions ranging from the stabilization of main group species with unusual electronic properties, to designing new bifunctional catalysts with abundant s- and p-block elements and the generation of versatile weakly coordinating anions.

Keywords: main group chemistry,organometallic chemistry,carbanions,ligand design