Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
NANOStructure Photochemistry via Hot Electron driven REactions (NANOSPHERE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-03-15
End date: 2017-03-14
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

The current research proposal aims utilise the unique macrocyclic host guest chemistry of cucurbiturils in conjunction with metal nanoparticles to demonstrate a novel and malleable approach to nanoparticle self-assembly, resulting in structures that will be used in light driven chemical reactions and advanced molecular sensing. This represents an important area of research, for whilst nanoparticles and assembled nanostructures show promise in a wide variety of applications, their uptake into current technologies has stalled due to the difficulty of their production, post-assembly manipulation and chemical loading. This project will demonstrate a new paradigm of functionality and versatility in nanoarchitectures. This will be achieved by assembling nanoparticle structures with a unique group of rigid macrocycle assembly agents, cucurbiturils. Cucurbiturils, with their versatile host-guest complexation chemistry, will allow for post assembly control of nanostructures via multiple external stimuli, while also giving flexibility in terms of application, with many kinds of molecules able to be loaded into the inner cavity of the cucurbiturils, yielding chemical sensing and reactor constructs on the nanoscale. Fundamental insights will be gained into the assembly and manipulation of nanoparticle superstructures, with an eye for application. To this end, Dr. Steven Barrow, the applicant, will work with Dr. Oren Scherman, in collaboration with Prof. Jeremy Baumberg. This linkage represents a unique opportunity to explore nanoscale systems at the University of Cambridge. This project will be highly supported in both the Chemistry department with Dr. Scherman, as well as the Physics department with Prof. Baumberg, at the University of Cambridge. The University of Cambridge is world renowned for its high impact research in the fields of chemistry and physics and this project represents a unique opportunity for collaboration between the two departments.
An advanced online anti-fraud software equipped with deep learning Artificial Intelligence that can face and detect, current fraudulent techniques and their continued evolution in a cost effective man (UNFRAUD)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Italy
Call: Engaging SMEs in security research and development (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-06-01
End date: 2017-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The impact of cybercrime is a growing concern in a society that increasingly interacts online. In the EU the cost of cybercrime has reached €871 billion a year and fraudulent card transactions amounted to €1.27 billion. The high number of online frauds coupled with the low level of cybersecurity deters businesses, and in particular SMEs who may not be able to afford comprehensive anti-fraud services, from fully exploiting the potential of e-commerce. UNFRAUD is a software product that prevents potential online fraud scenarios by analysing previous and current fraudulent invents through deep learning artificial intelligence to tackle the new challenges that fraudsters devise. UNFRAUD’s algorithms are similar to one’s used by Google for self driving cars and facial recognition (i.e. deep AI that recognizes human errors, behaviours and surroundings) and through this deep learning it is able to detect "fraudulent" behaviour. This makes UNFRAUD much more reliable as well as greatly reducing the cost of anti-fraud services, allowing companies to operate and grow safely. During the Phase 1 feasibility study the project will focus on identifying and securing the key partners required for commercialisation, establishing a sound business model and commercialization strategy, and planning a pilot test with a bank, big e-commerce, enterprise, telecommunication company and public administration in order to fully demonstrate and assess the products capabilities.

Keywords: anti fraud,cybersecurity,ecommerce,deep learning,artificial intelligence
Induced pluripotent stem cell-based therapy for spinal regeneration (iPSpine)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Ireland,Italy,Germany,Germany,Hong Kong,Switzerland,Switzerland,France,France,France,Netherlands,Netherlands,Netherlands,Netherlands,United States,United Kingdom
Call: Innovation platforms for advanced therapies of the future (H2020-SC1-2018-Single-Stage-RTD, 2018)
Start date: 2019-01-01
End date: 2024-06-30
Duration (months): 66.0
Total project cost (EUR): 15396031.25
EU funding (EUR): 14959781.25
Participants: 27
Project status: SIGNED

Low back pain (LBP) is a leading cause of disability and morbidity worldwide. It is widely accepted that a major contributor to LBP is intervertebral disc degeneration (IDD). IDD account for at least 40% (~280 million) of all LBP cases, leading to an EU-economic burden of ~€240 billion. These patients receive conservative treatment (e.g. pain relief medication and physiotherapy). When the latter is unsatisfactory, the only option left are invasive and costly surgical intervention. To date, no treatments halt or reverse IDD. Despite the profound socioeconomic burden and impact of IDD, decreasing the quality of life of millions of people, a game-changing treatment strategy for IDD-induced LBP is almost non-existent. The iPSpine consortium was formed to initiate a European-led research effort to identify a future advanced therapeutic strategy that results into a radical new treatment of IDD-induced LBP. With their multi-disciplinary expertise in the development of advanced therapies and their translation from bench to bedside, the aim of the iPSpine team is to investigate and develop a new advanced therapy medicinal product (ATMP) of the future, based on a novel developmental biology-based therapeutic strategy employing pluripotent stem cells (iPSC) and smart biomaterials. The iPSpine consortium will develop and demonstrate Proof-of-concept with the aid of novel and extended knowledge, tools and technology platforms. Hereby, iPSpine has the ambition to make a significant contribution by reducing translational bottlenecks through open innovation and take European leadership in the development of ATMPs. The iPSpine impact: iPSpine seeks to offer novel technologies and ATMPs for the advanced therapy research and development community. IDD will be the showcase, offering improved quality of life for millions of patients with IDD-induced LBP, through long-lasting reduction of LBP, reduced LBP-related premature retirement, and improved socio-economic contribution.

Keywords: induced pluripotent stem cells,biomaterials,intraventricular disc degeneration,regenerative medicine
High Phytosterol variants towards improved feedstocks and biofortification of crops (HiPhy)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

Phytosterols (PS) are valuable biomolecules used as nutrients and as feedstock material for the pharmaceutical and cosmetic industries. The challenge biologists and breeders are faced with is to develop bioengineering programs and valuable crops dedicated to the large-scale production of PS, which are currently extracted from agricultural waste materials. The goal of the proposal is to identify master regulators of PS biosynthesis and accumulation in plants. In fact, PS have essential cellular functions in plant growth and development, acting as key membrane components and membrane reinforcers, as signals in development and as precursors of brassinosteroids, a class of growth regulators. As such, the concentration of PS is highly regulated in order to comply with cellular homeostasis. To reach the goal, we will carry out a functional molecular characterization of a tobacco variant carrying a yet unknown semi-dominant mutation responsible for PS overproduction and Arabidopsis thaliana mutants exhibiting a suppressor phenotype of a defect in the production of precursors of isoprenoid lipids, such as PS. The work plan is to apply advanced genomics for next-generation mapping, leading to the elucidation of mutations in genes of interest (GOI) that regulate PS accumulation. The validation of candidate GOI will be done by genome editing and the role of novel alleles in PS metabolism will be performed by various functional and metabolomic studies. Finally, the combined expression of selected GOI with steroidogenic enzymes will be assessed by implementing in folia expression assays in Nicotiana benthamiana.

Keywords: phytosterols,metabolism,biosynthesis,regulation,sterol esters,genetics,genomics,crops,phytosterol market
Circular High-performance Aza-Michael Polymers as Innovative materials Originating from Nature (CHAMPION)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Public-private partnerships
Destination: Bio-based Industries
Action type: Research and Innovation actions
Partnership: BBI (Art-187)
Countries involved: Germany,Belgium,Finland,Switzerland,Belgium,Netherlands,Netherlands,Netherlands,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: Develop bio-based high-performance materials for various and demanding applications (H2020-BBI-JTI-2019, 2019)
Start date: 2020-06-01
End date: 2024-05-31
Duration (months): 48.0
Total project cost (EUR): 5724698.44
EU funding (EUR): 4847078.75
Participants: 16
Project status: SIGNED

The objective of CHAMPION is to develop and demonstrate that novel bio-based polymers can be efficiently synthesised and applied in high-performance applications, beyond plastics, where the current petrochemical-derived materials are not fully fit for purpose. Technologies to be developed in CHAMPION include the reductive amination of bio-based chemicals to create novel sustainable diamine monomers, application of aza-Michael chemistry onto fully bio-derivable polymers, and bio-based unsaturated polyesters from secondary alcohol diols on a kilogram scale. The new materials will be specifically circular by design and assessed as such, thus making them superior to current materials by ensuring that (chemical) recyclability or biodegradability are possible. Applications will be tested by four relevant industry end-users in the coatings, textiles, home care formulation, and structural adhesives sectors. Up to 12 bio-based materials will be subject to advanced performance testing after preliminary screenings of many more candidates. The toxicity of materials, their precursors, and break-down products (e.g. during biodegradation) will be evaluated, as well as the environmental, economic, and social impact of the new bio-based value chains these materials create (safe by design). A cradle-to-grave sustainability assessment will use the benchmarks set by commercial products to quantify performance, resource efficiency, and reduced greenhouse gas emissions. The producers of two bio-based chemical intermediates in the consortium will form new cross-sector interconnections with the four end-users creating increased business and job opportunities. Dissemination and exploitation of results will be conducted to establish the basis of new value chains and inform Standards fit for describing new applications of bio-based products. At least two bio-based materials are targeted to reach TRL 5, with others in the pipeline for further development as part of the legacy of the project.

Keywords: aza michael addition,bio based diamines,bio based thermosets,water soluble polymers
A look inside the proton: polarized transverse momentum dependent parton distributions for modern collider experiments (ProtonSpin)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Duration (months): 24.0
Total project cost (EUR): 178320.0
EU funding (EUR): 178320.0
Participants: 1
Project status: CLOSED

One of the big open challenges in contemporary particle physics is the quest for the three-dimensional structure of the proton, a principal building block of all visible matter. According to the theory of Quantum Chromodynamics, which is well-established since the mid-seventies, the proton is a composite particle built from elementary point-like particles known as quarks and gluons, or collectively 'partons'. A simple picture in which these quarks and gluons are quasi-free and move alongside their parent proton, is often very successful in describing experiments at particle colliders. However, this so-called 'collinear' framework is challenged in many experiments that are sensitive to the internal motion of the partons or to the spin degrees of freedom. Moreover, being strictly one-dimensional, it cannot account for some of the proton's main properties such as its spin, a long-standing and still unresolved problem known as the proton spin puzzle. Hence, in order to formulate an answer to such fundamental questions, it is necessary to explore the full three-dimensional structure of the proton. This structure needs to be extracted from experimental data, and can be encoded into so-called transverse momentum dependent parton distribution functions (TMDs). In this research project, I will study polarized TMDs, which are nowadays still very poorly known but are key to solve the aforementioned puzzles. For my study, I will capitalize on a new approach to TMD phenomenology, the Parton Branching method, as well as recent data from COMPASS at CERN, HERMES at DESY, and Hall A at JLab. This project is extremely timely, since the study of TMDs is a driving force behind several proposed new experiments in the US and in Europe, such as the recently approved Electron-Ion Collider.

Keywords: spin physics,hadron physics
Demonstration of Innovative Technologies towards a more Efficient and Sustainable Plastic Recycling (POLYNSPIRE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Sustainable, resource-efficient and low-carbon technologies in energy-intensive process industries
Action type: Innovation actions
Countries involved: Spain,Spain,Spain,Italy,Italy,Italy,Germany,Spain,Türkiye,Türkiye,Slovenia,Belgium,Slovenia,France,France,Czechia,Netherlands,United Kingdom,Denmark
Call: Efficient recycling processes for plastic containing materials (IA) (H2020-NMBP-SPIRE-2018, 2018)
Start date: 2018-09-01
End date: 2023-02-28
Duration (months): 54.0
Total project cost (EUR): 9811952.5
EU funding (EUR): 7944009.27
Participants: 28
Project status: SIGNED

The main objective of POLYNSPIRE is to demonstrate a set of innovative, cost-effective and sustainable solutions, aiming at improving the energy and resource efficiency of post-consumer and post-industrial plastic recycling processes, targeting 100% waste streams containing at least 80% of plastic materials. To this end, three innovation pillars are addressed at TRL7: A) Chemical recycling assisted by microwaves and smart magnetic catalysts as a path to recover plastic monomers and valuable fillers (carbon or glass fibres), B) Advanced additivation and high energy irradiation to enhance recycled plastics quality and C) Valorisation of plastic waste as carbon source in steel industry. Innovations A and B can lead up to 34% of fossil fuel direct reduction for PA and 32% for PU. Approach C can lead to reductions of around 80% of fossil carbon sources in electric arc furnaces. The demonstration is completed by the performance of a rigorous holistic environmental and economic analysis (LCA and LCC) to ensure the industrial feasibility and the accomplishment of environmental restrictions. Efforts are dedicated to analyse non-technological barriers (legislative or standardization) that could hinder the proper innovations deployment. POLYNSPIRE also implies the development of a comprehensive business plan, gathering 7 business models and establishing a cross-linked relation between plastic, chemical and steel manufacturing industries. Its consortium, coordinated by CIRCE, ensures POLYNSPIRE success through the involvement of 4 RTOs, 1 university, 9 large companies, 6 SMEs and 2 multiplier associations. To that end, chemical companies (REPSOL QUIMICA, ARKEMA, NOVAMONT, NUREL and KOR), plastic compounders (BADA) and converters (MAIER), waste managers (IDS), technology developers (CIRCE, NIC, ION, AITIIP, TUe, CSM), equipment and steel manufacturers (FM, CPPE, HTT, FENO), exploitation (VTG), standardisation (DS) and dissemination (EUPC and IKMIB) entities are involved in the consortium.

Keywords: polymer,spire,chemical industry,steel industry,vitrimers,automotive,polyamide,polyurethane,polyolefin,microwave,magnetic catalyst,recyling
Platform Universal Self Hosting, a hybrid-cloud Platform as a Service reducing web application development cost by 40% for SMEs (PLUSH)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: France
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-2-2014, 2014)
Start date: 2015-05-01
End date: 2017-04-30
Duration (months): 24.0
Total project cost (EUR): 2800000.0
EU funding (EUR): 1960000.0
Participants: 1
Project status: CLOSED

The PLUSH project is meant to create a next generation PaaS (Platform as a Service) – that can run multiple applications in multiple computing languages using multiple data backends on a Hybrid-Cloud infrastructure. PLUSH will be the first self-hosted PaaS (able to deploy itself on any private or public cloud) which thus will generate different deployment modes for client applications (public cloud, private cloud, as a hybrid-cloud, on multiple clouds). PLUSH will be a distributed and decentralized system powered by a high-availability grid of micro-services. There has been a recent strong trend to unify software development and operations in order to reduce release cycle times and gain in quality and velocity. Following this trend, PLUSH project addresses the web development market on these two converging segments, the web application development tools market and the web application hosting market. Within the two year period of the project, three pilots will be respectively conducted respectively within a web agency, a high-growth SaaS SME and a public sector entity to validate the PLUSH platform and the productivity gains on the key targeted markets. With PLUSH, Commerce Guys an open source start-up, will maintain its current technological advance thanks to the evolution of its existing PaaS “platform.sh”, that has already been deployed by 200+ clients since its launch, 5 months ago. This advance stems from its mature container based micro-services architecture, technology which has been recently adopted by leaders such as Amazon, Google and Microsoft. Commerce Guys business ambition is to reach 5% of the PaaS market segment in Europe and in the US within the next 5 years, with a 9M€ revenue milestone for the full year of 2017. Our business plan relies on three sales channels, the major one consisting in leveraging existing partnerships with more than 550 integration partners (web agencies), inbound sales and online self-service.

Keywords: cloud computing,hybrid cloud,platform as a service,agile software development
Culture Aware Robots and Environmental Sensor Systems for Elderly Support (CARESSES)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: Research and Innovation actions
Countries involved: Italy,Sweden,France,United Kingdom,United Kingdom,United Kingdom
Call: EU-Japan cooperation on Novel ICT Robotics based solutions for active and healthy ageing at home or in care facilities (H2020-SC1-2016-CNECT-EUJ, 2016)
Start date: 2017-01-01
End date: 2020-01-31
Duration (months): 37.0
Total project cost (EUR): 2084248.75
EU funding (EUR): 2084248.75
Participants: 6
Project status: CLOSED

The groundbreaking objective of CARESSES is to build culturally competent care robots, able to autonomously re-configure their way of acting and speaking, when offering a service, to match the culture, customs and etiquette of the person they are assisting. By designing robots that are more sensitive to the user’s needs, CARESSES’ innovative solution will offer elderly clients a safe, reliable and intuitive system to foster their independence and autonomy, with a greater impact on quality of life, a reduced caregiver burden, and an improved efficiency and efficacy. The need for cultural competence has been deeply investigated in the Nursing literature. However, it has been totally neglected in Robotics. CARESSES stems from the consideration that cultural competence is crucial for care robots as it is for human caregivers. From the user’s perspective, a culturally appropriate behavior is key to improve acceptability; from the commercial perspective, it will open new avenues for marketing robots across different countries. CARESSES will adopt the following approach. First, we will study how to represent cultural models, how to use these models in sensing, planning and acting, and how to acquire them. Second, we will consider three (physically identical) replicas of a commercial robot on the market and integrate cultural models into them, by making them culturally competent. Third, we will test the three robots, customized for three different cultures, in the EU (two cultural groups) and Japan (one cultural group), on a number of elderly volunteers and their informal caregivers. Evaluation will be conducted through quantitative and qualitative investigation. To achieve its groundbreaking objective, CARESSES will involve a multidisciplinary team of EU and Japanese researchers with a background in Transcultural Nursing, AI, Robotics, Testing and evaluations of health-care technology, a worldwide leading company in Robotics and a network of Nursing care homes.

Keywords: transcultural nursing,culturally competent robots,cultural knowledge representation,culturally sensitive planning and execution,culture aware human interaction,smart ict environments