Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Fourier Interpolation and Extremal Problems (FourIntExP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-05-01
End date: 2028-04-30
Duration (months): 60.0
Total project cost (EUR): 1158000.0
EU funding (EUR): 1158000.0
Participants: 1
Project status: SIGNED

In 2006 Cohn and Kumar have conjectured that the A2 lattice is universally optimal, meaning that it has the lowest potential energy among all configurations of the same density for all completely monotone potentials. This conjecture has several very important corollaries. Among other consequences, it is known that it implies a positive solution to the 2D crystallization problem, a major unsolved problem coming from materials science, and it also implies a conjecture on the emergence of the triangular lattice of Abrikosov vortices in the Landau-Ginzburg theory of superconductivity. Recently, the 8 and 24-dimensional cases of the Cohn-Kumar conjecture have been positively resolved using novel interpolation formulas for radial Schwartz functions. This formula recovers a radial function from the data of it and its Fourier transform on a discrete set of radii, and its construction uses classical modular and quasi-modular forms. In this project we will prove a significant generalization of these interpolation formulas with a view towards applications in extremal problems in Fourier analysis. To prove these formulas we will develop new analytic and numerical techniques for solving certain types of functional equations in one complex variable. Finally, based on these proposed interpolation formulas we will give a refinement of the Cohn-Kumar conjecture in dimension 2 and use it to attack the full conjecture in this case.
Furniture Renewal and Alternative New Circular Efficiency Strategies through Creative Approaches (FRANCESCA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Innovation actions
Countries involved: Spain,Finland,Sweden,Poland,Belgium,Portugal,Italy
Call: Innovative circular solutions for furniture (HORIZON-CL6-2024-CIRCBIO-01, 2024)
Start date: 2025-11-01
End date: 2028-10-31
Duration (months): 36.0
Total project cost (EUR): 5389955.0
EU funding (EUR): 4755967.25
Participants: 15
Project status: SIGNED

FRANCESCA aims to provide crucial support to the EU furniture industry as it moves towards greater circularity. The project's primary objective is to pioneer innovative circular solutions for furniture, encompassing the whole funiture life cycle, including pre-use (from design to delivery), use (maintain, reuse, repair), and post-use (refurbish, repurpose, re-manufacture, re-distribute, and recycle). FRANCESCA will develop and use enabling supporting solutions that address key design, materials, and business model challenges. Concretely, the project develops, tests and disseminates a circular furniture design decision support tool, bridging circular principles with market-based instruments (environmental certifications and standards); it investigates, scopes, and tests alternative biobased materials to accelerate closed-loop strategies by implementing a dedicated industrial symbiosis platform; it designs, prototypes and implements a set of complementary circular business models; develops circular ecosystem management guidance and integrate circular value creation mechanisms enabled by Digital Product Passports. These enabling tools feed a set of three Circular Demonstrators, each focusing on a key circular strategy (design, material innovation, and service business model). Sustainability assessements and environmental technology validation of the novel solutions demonstrate their sustainability potential at scale. Finally, learnings from the project are cristallised in a capacity building toolkit for life-long learning strategies and a set of policy recommendations that are disseminated at EU level. The pragmatic, holistic and hand-on approach, steered by sectoral needs (manufacturers, retailers, CSOs) and supported by a complementary set of design, materials, business and sustainablity experts breaks down the systemic barriers to circular transition and reduces the circularity gap faced by the sector, thus creating long lasting sustainable impact.

Keywords: furniture,industrial symbiosis,marketplace,dpp,etv
NEW TECHNOLOGIES FOR AFRICAN SWINE FEVER VACCINES (VAX4ASF)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Spain,Hungary,United States,United Kingdom,Germany,Poland,Kenya,Sweden,Italy,Netherlands,Romania
Call: Advancing vaccine development for African swine fever (HORIZON-CL6-2023-FARM2FORK-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 5234950.0
EU funding (EUR): 5234950.0
Participants: 19
Project status: SIGNED

VAX4ASF aims to develop a state-of-the-art platform to produce highly effective and safe vaccines against ASFV targeted for both domestic pigs and wild boars. These vaccine candidates will be designed based on an innovative and robust vaccine platform that will guarantee immune protection against the different circulating ASFV variants in Europe, while avoiding the safety concerns arisen with the use of traditional live attenuated vaccine platforms. Vaccine candidates will effectively induce innate immune response with the adequate adaptive immunity. Moreover, the immunity induced will allow discrimination between vaccinated and infected animals, which will be monitored by complementary DIVA tests developed under the scope of the project. Given the complexity of ASFV genome and the still incomplete knowledge of the mechanisms involved in immune response to ASFV, VAX4ASF aims to further understand the molecular mechanisms of the virus and how it interacts with the host. The developed platform can be used to introduce new mutations based in this new generated knowledge which will allow to improve the efficacy and cross-protection of the vaccine prototypes. VAX4ASF will provide new virus epidemiology models and control strategies using different mathematical models, leading to a better understanding of the ASFV transmission at the wild-domestic interface. In this way, innovative policies and strategies for ASFV control and management will be generated to ensure an outstanding impact through the continuous involvement of key stakeholders as project partners (farmers, wild board managers, veterinaries, hunters, policy makers...), leading to a profound effect in animal health and worldwide economy. The project relies on a solid collaboration trajectory between leading developers of innovative Animal Health vaccines and the highest experts in ASF field at international level, including partners from Europe, USA, and Kenya for the achievement of this challenge.

Keywords: asf,asf virus,pilot vaccines,diva test,genetics,immune response,surveillance,control strategies,epidemiology,veterinary,farmers,hunters
The possibility of artificial life at subzero temperatures: the role of water in cell-mimicking compartments (ArtWater)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1749375.0
EU funding (EUR): 1749375.0
Participants: 1
Project status: CLOSED

In the last few decades, researchers have come to believe that where there is liquid water, there is life, regardless of the physical conditions of the surroundings. Indeed, living organisms have been discovered in environments with extreme temperatures, radiation, or high salinity. In terms of temperature, the lowest limit to sustain the metabolic activities of bacteria is reported to be -20 ºC in permafrost. Yet, the survival mechanism of life below the freezing point of water is still not fully understood, though it has important implications for origin of life studies and the search for life in the universe. The prerequisite of life at subzero temperatures is the existence of liquid water. Intracellular liquid water not only serves as solution medium, but also plays a crucial role in biological processes such as metabolisms in cells. Therefore, understanding the physical state of intracellular water at subzero temperatures is important. In ArtWater, we will employ synthetic compartments as model system to investigate the physical state of compartmentalized water at subzero temperatures. The project will be conducted through a bottom-up approach: from pure water in compartments to crowded compartmentalized solutions that mimic cytoplasm in natural cells. The crystallization, diffusion, and dynamics of water will be studied by differential scanning calorimetry, nuclear magnetic resonance, and broadband dielectric spectroscopy, respectively. Several types of state-of-the-art synthetic compartments will be employed including polymersomes, liposomes, and complex coacervates. Furthermore, we will develop artificial cells equipped with liquid water enabling biological activities at subzero temperatures. The ArtWater project will not only open the window for understanding the survival mechanisms at extremely low temperatures but also provide a new platform for tunable bioengineering processes such as cryopreservation and cryo-enzymology and shed light to astrobiology.

Keywords: origin of life,astrobiology
Advanced AI for Optimised Knowledge Capitalization (BABEL)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Ask for the Moon (Ask) is developing a software solution, based on artificial intelligence (AI), that will perpetuate French and European industrial know-how and contribute to the reindustrialisation as it moves towards Industry 5.0, while preserving and improving its industrial sovereignty. The solution we have developed consists of software for business that makes it easy for business teams to ask the right questions to the right colleagues in a highly secure, intelligent platform. The aim is to provide a new and disruptive solution which, using AI-based models, connects an employee with a question to a colleague identified as being able to answer it. Achieving this objective would confirm Ask's mission: To create the quickest way to the knowledge the industry needs, we build the shortest route to the people who know. Therefore, our ambition is to become the leading generative AI knowledge management system. We aim to finalise the synergies between the three main components — ontology, large language model (LLM), and vector database — creating new industrial standards. Our developments will adapt LLM to organisational contexts through structured knowledge maps and Retrieval Augmented Generation (RAG). Initial implementations at Framatome and Airbus will refine our models and advance our solution from TRL 5 to 8 over 24 months with a budget of €3.5 million. Our go-to-market strategy targets key stakeholders, aiming for significant market share and projected turnover growth to 600 million in 10 years. We foresee a disruptive impact by transforming ways of working all over Europe, fostering innovation, empowering employees, making them save time, improving professional / personal life balance and bringing a solution to the tremendous challenge the demographic situation and forecast is representing. Additionally, this will directly result in the creation of 100 full-time jobs and a cumulative turnover of more than 234 M€ within the next 6 years.

Keywords: human centric generative ai knowledge management
Miniaturized Array of Gas Integrated Circuit Sensors (MAGICS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Belgium
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

VOCSens, founded in 2019 as a spin-off from the Université catholique de Louvain (UCL) in Belgium, aims to meet the global demand for precise and cost-effective gas sensors. These sensors facilitate accurate monitoring of gas emissions and indoor air quality across various industrial sectors, ensuring ambient air quality and safety, tracking the effectiveness of interventions, and enabling compliant impact reporting. The widespread adoption of accurate emission and air quality monitoring is currently limited by existing sensing technologies that fail to provide the necessary miniaturization, durability, and versatility for effective pollutant and hazardous gas detection. VOCSens addresses these challenges by developing and marketing highly selective and affordable multi-gas sensing technology, utilizing its patented CMOSEnvi™ technology. This technology, based on nanomaterials integrated on a semiconductor chip, allows for up to 16 multi-gas measurements with high selectivity and exceptional durability. VOCSens stands out as the only company offering multi-gas detection on a single sensor while ensuring miniaturization, selectivity, and a low total cost of ownership. While our sensors can be used in various industries, our initial market focus is on the agricultural sector, particularly livestock farming, and the smart building industry. With support from the EIC, we aim to complete crucial development steps to achieve TRL 8, capitalize on market opportunities, and successfully enter the market, thereby creating significant economic and environmental impacts.

Keywords: multi gas sensors,semiconductor based sensors,ammonia sensor,
LuSeed DOME™ A novel device for effective treatment of brain aneurysms (LuSeed DOME)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Cerebral aneurysms affect approximately 3% of the global population, with a rupture risk of 2-10%. Rupture leads to fatal cerebral hemorrhage in 50% of cases, resulting in around 500,000 deaths annually. Alarmingly, half of these deaths occur in individuals under 50. Survivors of ruptured aneurysms face a grim prognosis: about 66% suffer permanent neurological deficits, and 15% die before reaching the hospital due to rapid, massive brain injury. While medical interventions exist, they come with significant limitations and a high risk of complications. LuSeed DOME™, the world's first intrasaccular device, offers a groundbreaking solution for treating both bifurcation and sidewall aneurysms. Its novel mesh design ensures easy delivery and intuitive implantation, irrespective of the aneurysm's angle. Its suitability for ruptured cases simplifies treatment compared to complex endovascular surgeries, and its geometry enhances long-term occlusion rates. To date, Luseed has completed their first-in-human phase study with positive results. With the EIC project, LuSeed intends to complete clinical validation, achieve regulatory approvals including the CE Mark for commercialisation in Europe, and finally launch their product on the market.

Keywords: cerebral aneurysms,wide neck aneurysms,interventional treatments,nitinol micro braided mesh and vascular tissue growth
Acceleration Towards LEO Automatic Space Safety (ATLAS2)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator Challenge: Customer-driven, innovative space technologies and services (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 3444985.0
EU funding (EUR): 2411489.5
Participants: 1
Project status: SIGNED

The ATLAS² project aims at developing the first service of Space Safety. Based on a network of 7 radars deployed around the world with a new design for scanning and tracking, capable to detect debris down to centimetric size, and through fusing data from its network and other sources, Look Up Space aims at extending the lifetime of satellites through collision avoidance and decreased number of collision avoidance manoeuvres of satellites. This service will be applicable to small satellite fleets as well as to whole satellite constellations. This will provide the EU with the first sovereign solution for space safety, dedicated to coordinating all stakeholders and automatising processes.

Keywords: space safety,satellites,collision avoidance,space situationnal awareness,space traffic management
Cellevat3d™ Microcarriers - the 1st nanofiber-based microcarriers designed for gene therapy biomanufacturing (Cellevat3d)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 4000000.0
EU funding (EUR): 4000000.0
Participants: 1
Project status: SIGNED

Biological products (biologics) like vaccines, therapeutic proteins, monoclonal antibodies, and cell- and gene therapy products represent a new medical paradigm, offering remarkable patient outcomes and revolutionizing disease treatment. However, manufacturing biologics is more challenging than small-molecule drugs, with low product yields, high costs, and limited cell viability. Even minor process changes can affect biologic safety and efficacy, complicating the scale-up from research to clinical production. This complexity limits many promising therapies from reaching the market. A key issue is the technological limitations of microcarriers used to cultivate cells in bioreactors. Current microcarriers have Specific Surface Areas (SSAs) of 0.5 - 1.1 m²/g, insufficient for high cell densities. Additionally, reproducing complex cellular 3D micro-environments in existing carriers is difficult, which is crucial for optimal cell growth and function in vitro. Cellevate addresses these challenges with its innovative Cellevat3d™ microcarriers. These nanofibrous microcarriers are highly customizable, replicate the human extracellular environment, and offer up to 60 times more cell growth area compared to current solutions. Their unique properties stem from a patent-pending nanofiber scaffold production technology that creates polymer nanofiber networks, allowing cells to proliferate, migrate, and interact in 3D while maintaining an in-vivo-like morphology. Cellevate received EIC Accelerator blended funding in summer 2022. As a result, Cellevate will launch Cellevat3d™ nanofiber microcarriers for upstream bioprocessing in gene therapy by Q4 2024. To date, the EIC Fund has invested 2.6 MEUR in the company. Having met all commercial readiness milestones, Cellevate now seeks additional EIC equity of 4 MEUR for the A-round planned for the summer 2025. This capital will expand production, complete bulk product development, and scale up operations for commercial success.

Keywords: equity only,microcarriers,biomanufacturing productivity,biological products biologics,nanofiber
Innovative Solutions to Eliminate Domestic Abuse (ISEDA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Fighting Crime and Terrorism
Action type: Innovation actions
Countries involved: Germany,Greece,Bulgaria,France,Spain,United Kingdom,Cyprus,Finland,Italy
Call: Domestic and sexual violence are prevented and combated (HORIZON-CL3-2021-FCT-01, 2021)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 2947827.5
EU funding (EUR): 2678523.88
Participants: 15
Project status: SIGNED

The ISEDA project (Innovative Solutions to Eliminate Domestic Abuse) aims to combat and eliminate DV by employing an enriched European approach, utilizing modern technological tools and practices and improved multi-sectoral expertise in its activities. One of them is developing a chatbot, which will employ empathetic language and inform victims on ways to get help and assistance, as well as refer them to hotline numbers, police or other first responders to de-escalate violent situations. The chatbot will also familiarize citizens with the different types of DV, how to prevent, detect and investigate it. With victims’ consent, an integrated data platform will gather court-proof evidence to be used to build a legal case, and record trends on the nature, frequency and circumstances of the DV. A key activity of the ISEDA project will be providing training to primarily PAs through interactive learning. Participants will develop the necessary skills to better assess DV situations, respond accordingly and provide better assistance to victims and a just treatment to their cases. Awareness on DV will be further improved through campaigns integrating victims' input, via informational guides, posters and videos. Education Programs will focus on sensitizing and engaging students, fostering know-how on deconstructing toxic gender stereotypes and GBV and promoting healthy relationships and zero tolerance to violence. The ISEDA project will also promote and implement perpetrator programs as an alternative to imprisonment and a chance for positive change, as such programs have the potential to significantly increase the quality of life of both victims and perpetrators. Overall, the ISEDA project, employing multidisciplinary expertise and addressing the different aspects of DV, has the potential to significantly enhance the fight against DV on a European level and contribute to the establishment of the necessary robust long-lasting structures to eliminate it.