Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Spatio-Temporal Analysis of Ritual and Ancient Greek Experience of Sacred Spaces (STAR-AGESS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2024-02-29
Duration (months): 18.0
Total project cost (EUR): 120699.36
EU funding (EUR): 120699.36
Participants: 1
Project status: SIGNED

The experience of religious ritual played a key role in ancient societies, as it negotiated ideas of cosmology and identity. By addressing the cosmos, participation in rituals forged ideas of belonging, which increased social cohesion and negotiated power permeating all aspects of society. Despite its importance, ancient Greek ritual experience has only been studied from static temporal and spatial viewpoints. Religious processions, open-air ritual re-enactments and performances operated in three-dimensional spaces, linked to the movement of the participants and affected by the play of light, shadows and celestial bodies visible at the time when they were held. These elements were instrumental in shaping the experience and memories of the attendants, influencing the society as a whole. STAR-AGESS will provide a new approach to the study of ancient Greek ritual practice by recreating immersive environments that incorporate ancient sky and astronomical simulations, horizons, detailed topography and architectural 3D models of the sanctuaries at Sounion, Aegina and Perachora. These three key case studies were selected as they have enough extant remains and written information to allow meaningful reconstructions in an extra-urban environment. They will be virtually explored at specific times of the day/night and year to gain insights into religious practice, ritual timing, astronomical connections, and into how they might have shaped experience and social memory through specific socio-mythical associations. To do so, the Experienced Researcher (ER) will reconstruct the total environment with the aid of targeted hands-on-research training, using advanced 3D techniques, landscape analysis and current theoretical approaches on the cognitive formation of space and experience in ritual performance. These methods will enhance the ER’s profile with cutting-edge techniques that will situate her at the forefront of research and boost her career.

Keywords: ritual,sanctuaries,performance,archaeoastronomy,classical,archaeology,3d reconstruction,topography,landscape,perception,cognitive analysis,virtual reality
Replication and post-replication signalling pathways Regulating R-loop-associated Telomere instability in human cells (RTeRloop)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2024-04-01
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: SIGNED

Telomere stability is essential to prevent tumorigenesis and cellular senescence in human cells. Telomeres are transcribed into TERRAs, which has the ability to form R-loops with the DNA template. It is known that R-loops can hamper replication fork progression leading to hyperrecombination and genome instability. Indeed, R-loops are accumulated in telomeres of cancer cells that use the Alternative Lengthening of Telomere (ALT) maintenance mechanism to gain immortalisation and in ICF syndrome cells, associated with telomere shortening and senescence. The mammalian ATR-mediated replication stress signalling pathway and the RAD18-UBE2B ubiquitin-ligase complex involved in post-replication repair have been recently discovered as mains regulators of R-loop accumulation, suggested to act via different mechanisms. Interestingly, both pathways affect telomeres of ALT cells, where R-loops have been proposed as drivers of ALT recombination. Whether or not replication and post-replication signalling pathways have a differential role in telomeric R-loop control is not known, but it would be of key relevance to understand the role of R-loops in telomere dynamics both in normal and cancer cells. With this aim, we will investigate the molecular mechanisms that control pathological R-loop modulation at human telomeres by focussing into their accumulation during and after DNA replication and their regulation by replication and post-replication DNA damage responses. By developing new systems that allow a precise temporal control of R-loop levels and innovative single molecular approaches to detect R-loops at the replication fork, plus the use of and unbiased proteomics analysis of isolated chromatin from telomeres, I will identify new key factors and molecular mechanisms controlling telomeric R-loops in normal and cancer cells. This knowledge will help identify possible future targets in anti-cancer therapy that specifically affect cancer cells.

Keywords: genome instability,r loops,telomeres,replication stress,dna damage response,terra,alternative lengthening of telomeres,post replication repair
Predictive processes for intelligent behaviours, sensory enhancement and subjective experiences in robots (Predictive Robots)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-15
End date: 2021-05-14
Duration (months): 24.0
Total project cost (EUR): 183473.28
EU funding (EUR): 183473.28
Participants: 1
Project status: CLOSED

Current robot technologies are still not enough autonomous and adaptive to safely and intuitively interact with people. Nowadays, artificial systems mostly rely on pre-engineered models of the world and of their embodiment. Defining such models a-priori can be very challenging and may result in robots lacking the capability to react to situations that are not foreseen by their designers. The forthcoming societal needs and economic opportunities for robotics require smarter, more adaptive and self-aware artificial systems. This project addresses this challenge by developing new methods: (1) for the autonomous acquisition of models of the robot’s body inspired on infant development, where online deep learning techniques are integrated within curiosity-driven exploration strategies for high-dimensional task spaces; (2) for the enhancement of robots’ perceptual skills based on predictive processes, such as visual input enhancement through the attenuation of expected perceptions of self-body movements; (3) for studying possibilities of an artificial Self and of providing subjective experiences to robots. The core of the proposed research lays on predictive models learned through exploration behaviours typical of infants’ development. Predictive robots will be capable of anticipating sensory consequences of intended actions. This research has a broad range of applications - such as low-cost improvement of current sensing technologies - and can advance the understanding of brain processes behind particular phenomena - such as the sense of object permanence, memory, self-awareness and sense of agency - beside providing insights for their implementation into artificial systems. The research project will be conducted on humanoid robots and marine drones at the BioRobotics Institute of the Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna in Pisa, Italy.

Keywords: adaptive robots,intelligent behaviours,internal models,predictive models,sensorimotor predictions,exploration,self awareness,artificial self,sensory enhancement,humanoid robots,marine drones
B25Tr - New and innovative turbocharged engine (B25Tr)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-03-01
End date: 2019-07-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

B25Tr is a new and innovative turbocharged engine. The B25Tr will be proposed to the LSA and GA markets. To realize this product, it is necessary to upgrade the aspirated engine to a turbo-charged engine. The world of LSA manufacturers and that of aircraft engine manufacturers have advanced at two different speeds: the aircrafts have advanced rapidly and with obvious innovative transformations, while the engines have advanced slowly or almost still mainly due to the absence of competition. The LSA market is hungry for technological innovation and is rapidly expanding worldwide and therefore it needs engines with greater performance to better express the LSA aircraft potential. The GA market has stopped growing due to the high costs of purchase and maintenance. B25Tr introduces novelty and added value: it will offer the best power/weight ratio with the highest efficiency of the market of aero engines. It will be the only engine completely water cooled, with a gear box, fuel injection, SOHC, the crank shaft of ball bearing and connecting rod on needle bearing. B25Tr delivers tangible and direct benefits: it allows to use the engine at Hight altitude: the LSA aircrafts will have the possibility to use lightweight engines with more power, without loss of performance with altitude, so will be more competitive with the actual GA aircrafts. It allows to offer a new generation engine with better weight/power ratios and better performance. It allows to have cheaper purchase and maintenance costs. It allows to have a reduction of fuel consumption and polluting effects with greater attention to the environmental impact (20 litres/hour against the 40 litres/hours). B25Tr addresses the needs of a large B2B and B2C user B25Tr addresses the needs of the LSA and GA Market, based on aircraft characteristics. There is also the category of homebuilt aircrafts and drones used for border control and safety control. B25Tr’s Total Addressable Market (TAM) is 72bn EUR in EU 28.

Keywords: general aviation,sport aviation,engine,ultralight aircrafts,turbocharged engine,fuel efficiency,mechanical,engineering,propulsion systems engineering
The Comedy of Political Philosophy. Democratic Citizenship, Political Judgment, and Ideals in Political Practice. (Comedy and Politics)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Despite the rich history and contemporary relevance of the intersection of comedy, political practices, and political thought, comedy has thus far not received sustained attention in the field of political philosophy. This research programme will address this lacuna by developing parallels between (i) the specific outlook on human action offered by comedies and (ii) the perspective of a tradition of political thought known as political realism. The overall objective of this research programme is to demonstrate that comedy reflects the theoretical and methodological commitments of political realism, and to establish comedy’s contribution to realism by drawing out realism’s transformative potential. Three specific research objectives will be combined to support the overall objective. (a) The first objective will develop an account of democratic citizenship informed by comedy by exploring Aristophanes’ comedies. (b) The second objective will develop an account of political judgment informed by comedy, by analysing Machiavelli’s comedies and political writings in relation to each other. (c) The third objective will develop an account of the relation between ideals and practice in politics informed by comedy by drawing on theoretical reflections on comedy by Hegel, Vischer, and Marx. Each of the specific research objectives corresponds to a central feature of political realism. By developing these objectives through comedy, the researcher will explicate structural parallels between comedy and political realism. In each of the specific objectives, the transformative potential inherent in comedy will be elucidated. In doing so, the researcher will use insights derived from this parallel to develop a more nuanced understanding of political realism’s potential to conceptualize social transformation. Thus comedy transpires as the means through which the full potential of realism for political philosophy as a whole can be grasped for the first time.
FabLab as Entrepreneurship supporting tool for innovation agencies (FABLABIA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Germany,Czechia,Luxembourg
Call: Peer learning of innovation agencies (H2020-INNOSUP-2018-2019-05, 2018)
Start date: 2019-06-01
End date: 2020-11-30
Duration (months): 18.0
Total project cost (EUR): 50000.0
EU funding (EUR): 50000.0
Participants: 3
Project status: CLOSED

Fablabs – digital fabrication laboratory – enable creation of new enterprises, offers an environment supporting innovation, and makes prototyping more available and affordable. Nowadays, FabLabs are increasingly being adopted by schools, universities and museums as platforms for project-based, hands-on STEM education. Despite the fact FabLab is great tool supporting technological prototyping and fostering entrepreneurship and innovations, there are only a few innovation agencies in Europe which included this platform in its services for SMEs. Therefore the main aim of the proposed project FABLABIA – Fablab as entrepreneurship supporting tool for innovation agencies is to gather the experiences of innovation agencies who use FabLab as an innovation tool for the benefit of SMEs and to turn it into a codified good practice manual (DOP). The proposed project will have a direct positive impact on SMEs’ capacity in rapid prototyping and product testing. Innovation agencies will help these individuals with market research for their solutions. On the other hand, project will have impact on innovation agencies too. It will lead to improvement in the design and quality of delivered innovation support services. In the process, the FabLab business model and its adaptation to the local conditions, will be explored. This approach will facilitate the uptake of FabLab-based services for SMEs by any interested innovation support agency beyond the consortium members. In this way the project will contribute to raising the level of innovation support provided to SMEs throughout the EU.

Keywords: fablab,entrepreneurship support,rapid prototyping
Radiative transfer effects on air pollution dispersion in urban areas: from the street scale to the neighbourhood scale (URBANRAD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-01
End date: 2017-05-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

This project aims at understanding the effects of radiative transfer on air pollution dispersion in urban areas at both the street scale and the neighbourhood scale. Numerical models will be developed, for that purpose, that will help design and manage our cities, buildings and traffic systems in order to produce sustainable, safer, healthier, and more comfortable urban environments. Radiation modelling will be coupled with 3D fluid dynamics, urban geometry, particle and pollutant transport, traffic and environmental conditions to produce the first model able to take into account radiation transport effects at both street and neighbourhood scales. Benchmark numerical simulations at the street scale will provide detailed information on radiative transfer effects subject to various environmental conditions: presence of clouds, humidity, turbulence level, etc. These results will help to derive simple physically relevant models for the simulations at the, much more computationally expensive, neighbourhood scale. The intensive use of fully adaptive methods for both radiation and fluid dynamics will also contribute to make feasible the simulations at this scale.

Keywords: air pollution,radiative transfer,multi adaptive method,subgrid model
Macroporous Polymer Monoliths as a Low-Cost Bioanalytical Platform for Biopharmaceutical Glycoprotein (PoreSelect)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Ireland,Ireland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-02-15
End date: 2018-02-14
Duration (months): 24.0
Total project cost (EUR): 175866.0
EU funding (EUR): 175866.0
Participants: 2
Project status: CLOSED

Glycoprotein therapeutics are widely seen as the next generation of drugs. 80% of new therapeutic drugs in phase 3 development are ‘biologics’. However, the early detection of critical glycosylation changes in biopharma pro-duction (i.e. in the drug producing cells) and the rapid and sensitive identification and separation of closely relat-ed protein-drug glycoforms presents an industry wide problem. This project aims to develop a low-cost and easy-to-produce glycopeptide separation platform. This will be based on highly porous polyHIPE structures obtained from fast and scalable polymerisation and subsequently functionalised with reactive groups. The latter will be employed in the conjugation with novel recombinant lectins that have very selective carbohydrate-binding prop-erties. The separation of closely related glycoproteins will be investigated. Moreover, the integration of the lectin conjugated porous polymers into a device format will be addressed. This is a highly interdisciplinary project at the interface of polymer and material science, biotechnology and separation science. The applicants diverse experi-ence in academic and industrially informed projects makes him an ideal match for this project. It provides a unique environment for the researcher to develop his skills supported by unique scientific and complementary training and accelerate his academic career in applied material science. The dissemination of research results will target the professional audience as well the general public through outreach activities.

Keywords: emulsion templating,glycoprotein separation,bioligand conjugation
Novel nanoparticle enhanced Digital Materials for 3D Printing and their application shown for the robotic and electronic industry (DIMAP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Developing next generation nanomaterials, nanodevices and nanosystems
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Austria,Germany,Israel,Germany,Spain,Austria,Netherlands
Call: Additive manufacturing for tabletop nanofactories (H2020-NMP-PILOTS-2015, 2015)
Start date: 2015-10-01
End date: 2018-09-30
Duration (months): 36.0
Total project cost (EUR): 4997351.25
EU funding (EUR): 4997351.25
Participants: 13
Project status: CLOSED

The here proposed DIMAP project focuses on the development of novel ink materials for 3D multi-material printing by PolyJet technology. We will advance the state-of-the art of AM through modifications of their fundamental material properties by mainly using nanoscale material enhanced inks. This widens the range of current available AM materials and implements functionalities in final objects. Therefore applications will not be limited to rapid prototyping but can be used directly in production processes. DIMAP will show this transition in two selected application fields: the production soft robotic arms/joints and customized luminaires. In order to cope with these new material classes the existing PolyJet technology is further developed and therefore improved. The DIMAP project targets at the following objectives: additive manufactured joints, additive manufactured luminaires, ceramic enhanced materials, electrically conducting materials, light-weight polymeric materials, high-strength polymeric materials, novel multi-material 3D-printer and safe by design. With the development of novel ink materials based on nanotechnology improvement of the mechanical properties (ceramic enhanced and high-strength polymeric inks), the electrical conductivity (metal enhanced inks) and the weightiness (light weight polymeric materials) are achieved. Based on the voxel printing by PolyJet these new materials lead to a huge broadening of the range of available digital material combinations. Further focus points during the material and printer development are safe by design approaches, work place safety, risk assessment, collaboration with EU safety cluster and life cycle assessment. An established roadmap at the end of project enables the identification of future development needs in related fields order to allow Europe also in the future to compete at the forefront of the additive manufacturing revolution.

Keywords: digital multi materials,polyjet technology,additive manufactured joints,additive manufactured luminaires,nanoparticle enhanced inks,high strength polymeric materials,safe by design