Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The ultra thin, flexible, lightweight and endless scalable video foil for dynamic ambient lighting and outdoor displays (LED-foil-display)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-01-01
End date: 2024-12-31
Duration (months): 24.0
Total project cost (EUR): 2433750.0
EU funding (EUR): 1703625.0
Participants: 1
Project status: CLOSED

There is a huge demand for dynamic, digital displays and lighting solutions of surfaces, indoor and outdoor, in automotive, transportation, aviation and health. But state-of-the-art solutions are either limited to single color lighting with no individual control of LED pixels, or they are expensive, heavy, limited in size, shape, curvature and difficult to install. LightnTec is a leading innovator in Europe for light and its control on ultra-thin films and will exploit this business opportunity. ledTec.flex is ultra-thin, malleable, flat, large in scale, applicable indoors and outdoors, and digital – any size, any shape, any place, ultra-thin, ultra-lightweight. The technology offers a huge application potential as video foil in digital-out-of-home (DOOH), for medical illumination in healthcare, and for dynamic ambient lighting in trains, planes, vehicles and buildings. The EIC blended finance, will enable LightnTec to internationally deploy ledTec.flex and become the next EIC success.

Keywords: dooh,video display,led walls,human centric lighting,dynamic lighting,digital lighting,light on foil,interior lighting,ambient lighting,led,lighting
RE-IMAGINE-CROPS – A real-time mobile multimodal positron emission tomography and multiphoton endoscopic technology for REalistic in-field quantitative IMAGING of CROPS (RE-IMAGINE-CROPS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Finland,Italy,Netherlands,France,Austria
Call: EIC Pathfinder Open (HORIZON-EIC-2024-PATHFINDEROPEN-01, 2024)
Start date: 2025-05-01
End date: 2028-04-30
Duration (months): 36.0
Total project cost (EUR): 2999500.0
EU funding (EUR): 2999500.0
Participants: 9
Project status: SIGNED

Sustainable agriculture strategies have become central to European and global orientations as the demand of food increases with the rising world population. Current technologies qualitatively drive the application of Nitrogen (N)-fertilizers to stressed field areas but cannot precisely modulate the needed amount, resulting in dangerous N dispersion, ecological and economic losses. RE-IMAGINE-CROPS envisions applying basic plant science into crop management by quantitative “in-field” measurements of biophysical processes occurring at tissue and cellular level. The consortium will implement the first real-time in-field portable multimodal multiscale Positron Emission Tomography (PET)-Multiphoton Endoscope (ME) technology. PET measures the metabolic processes in the crops at the scale of hundreds of micrometers, while guiding the ME system to visualize functional mechanisms at a cellular level. The aim is to tailor the amount of fertilizer to be used by enabling measurement of functional processes reflecting the local and systemic crop signal pathways triggered by N-fertilizer shortly after application. RE-IMAGINE-CROPS involves real-time PET reconstruction, hydrodynamic modelling, optical fiber transmission optics, and features identification in multiple scales. It enables a new multimodal, mobile technology for the first time, with unprecedented spatial resolution (0.6 mm;1um) and real-time functionality at a rate of (2;10) Hz. These are enabled by a multimodal PET-ME tracer based on the Lifeact-Venus protein labeled with 89Zr. RE-IMAGINE-CROPS brings together eight institutions with leading scientists and cross-disciplinary expertise. Among them, EURO-BIOIMAGING ERIC and BFEDU, a large agrifood enterprise, will boost the impact and dissemination of this novel technology in to the European scientific and industrial landscape. On this basis, RE-IMAGINE-CROPS has the potential to support and shape the essential priorities in the EU’s future sustainable crop management.

Keywords: positron emission tomography,imaging,digital imaging,multiphoton endoscopy,digital precision agriculture
Maternal Interventions to Reduce Asthma: Targeting Novel Endotypes in Early Life (MIRA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2025-POC, 2025)
Start date: 2026-01-01
End date: 2027-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Asthma is a common childhood disorder with a heterogeneous presentation, representing multiple disease endotypes with distinct underlying mechanisms. Understanding these mechanisms in early life can enable personalised asthma prevention, addressing a significant unmet medical need, but no asthma/wheeze endotypes have been identified in young children that can be targeted. My preliminary findings from untargeted plasma metabolomics profiling in the COPSAC2010 and VDAART birth cohorts showed that maternal oxylipins, particularly undetectable 12-HETE, are associated with a distinct asthma endotype. Further, preliminary data showed a primary preventive effect of n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation in pregnancy only among mothers with detectable 12-HETE levels, highlighting a potential for personalised prevention. The MIRA project aims to uncover the mechanisms behind this novel oxylipin-associated childhood asthma endotype and develop tailored prevention strategies. This involves measuring targeted oxylipin profiles and investigating the determinants of maternal oxylipins during pregnancy and their impacts on infant alveolar macrophages (AMs), airway microbiome, longitudinal metabolome and proteome, and asthma outcomes in COPSAC2010 and VDAART. The project will also explore personalised strategies involving prenatal n-3 LCPUFA exposure. Mechanistic studies using wild-type and ALOX15-/- transgenic mice will evaluate the effects and uncover the mechanism. A key innovation of this project is the development of dry blood spot (DBS) screening tool for pregnant women, enabling early risk stratification and personalised intervention. The project will engage in patenting, technology transfer, intellectual property protection, and prototype validation with industry partners, paving the way for integrating the screening tool into prenatal care to prevent childhood asthma before birth.
develoPpement of a rad-hard fpga with Ultra deep subMicron technology for spAce applications (PUMA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Space
Destination: Open Strategic Autonomy in Developing, Deploying and Using Global Space-Based Infrastructures, Services, Applications and Data
Action type: Research and Innovation actions
Countries involved: France,Germany,Italy
Call: Space technologies for European non-dependence and competitiveness (HORIZON-CL4-2024-SPACE-01, 2024)
Start date: 2025-01-01
End date: 2027-12-31
Duration (months): 36.0
Total project cost (EUR): 4302398.06
EU funding (EUR): 3060053.64
Participants: 5
Project status: SIGNED

The PUMA project sets clear and measurable main objectives to reach a TRL 5 from TRL 3 as follows: 1. Define future FPGA requirements for high performance space applications. 2. Provide benchmark to assess technology requirements 3. Define future FPGA architecture to meet applications requirements 4. Design of all FPGA architecture building blocks taking into consideration performance requirements 5. Test chip to validate reliability and radiation hardening performance of 7nm FinFET

Keywords: fpga,efpga
Vectors to Accessible Critical Raw Material Resources in Sedimentary Basins (VECTOR)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Germany,Ireland,Bulgaria,United Kingdom,Serbia,Spain,Canada
Call: Innovation for responsible EU sourcing of primary raw materials, the foundation of the Green Deal (RIA) (HORIZON-CL4-2021-RESILIENCE-01, 2021)
Start date: 2022-06-01
End date: 2025-05-31
Duration (months): 36.0
Total project cost (EUR): 5598316.84
EU funding (EUR): 5598316.84
Participants: 20
Project status: SIGNED

The EU imports 80% of its industrial raw materials making European supply chains highly vulnerable to disruption and threatening the EU's ability to manufacture raw material-intensive technologies, such as electric cars, wind turbines, and ICT hardware, that are essential to the green and digital transformations. Europe possesses significant mineral potential but development is limited by the lack of sustainable, low-impact exploration methods and by social opposition to mineral projects. With VECTOR we will generate new knowledge to overcome these technical and social barriers, unlocking Europe's raw material potential and improving the resilience of EU raw materials supply chains. Overcoming issues will require major changes of the business models in the extractives industry and to integrate a more human-centred approach. The VECTOR project is based on the premise that a prerequisite to any sustainable human activity is to minimize the environmental and social costs and include all the stakeholders in the decision making processes around this. VECTOR's overall objective is to deliver evidence-based and accessible knowledge that integrates the scientific and social pathways to successful mineral exploration and mining. The first pillar of our approach is a geological prospectivity toolkit based on an entirely new workflow using machine learning-based integration of less invasive geological, geochemical and geophysical measurements. The workflow will be validated in three European sedimentary basins and will be transferable worldwide. The second pillar is a social acceptance procedure that identifies, for the first time, the values that the European public invokes when deciding about mineral development. This will result in a Social Acceptance index and a new body of knowledge that reflects diverse values-based perspectives. The third pillar is an integrated toolkit consisting of a unique, distributed, multimodal, self-learning, and interactive platform that will consider both geological exploration potential and socio-economic factors to yield a data-driven, quantitative and integrative assessment of regions more suitable for exploration and, eventually, mining. The results will be freely available via an engaging, web-based interface designed to support evidence-based decision making and the UNFC and UNRMS.

Keywords: exploration social science
Understanding the ion distribution in LECs (UNID)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden,Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-05-01
End date: 2026-04-30
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 3
Project status: SIGNED

Sustainable, recyclable, and low-cost light-emitting technologies are projected to revolutionize the lighting market by introducing new applications in disease treatment, packaging, architecture, and fashion. The light-emitting electrochemical cell (LEC) may become such a disruptive lighting technology. It can be fabricated from biodegradable materials using cost-efficient printing or coating and offers soft areal emission from flexible and thin luminaires. In contrast to established (organic) LEDs, an LEC comprises only one active layer in which an organic semiconductor is blended with an electrolyte. Under operating voltage, the mobile ions redistribute and form self-organized charge-injection and transport regions. While being a promising concept for versatile, next-generation lighting, LECs currently suffer from inadequate operating lifetime and efficiency. Recent data suggest that the same ion redistribution that enables single-layer functionality also induces severe exciton-polaron quenching. This causes a reduction in light emission by about a factor of two and fast material degradation. Building on this new insight, I want to combine the expertise of OPEG, a leading group in LEC research, with my knowledge in optoelectronic characterization and modeling to develop a better understanding and control of the ion redistribution process in LECs. The associated suppression of ion-induced exciton-polaron quenching has the potential to enhance the LEC efficiency and lifetime towards industrial relevance, rendering it a promising next-generation light source.

Keywords: light emitting electrochemical cell,organic semiconductors,exciton polaron quenching
Autonomous robotics and digital TWIN to improve water network performances (CleanWaterPathfinder)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2024-03-01
End date: 2026-02-28
Duration (months): 24.0
Total project cost (EUR): 3540300.0
EU funding (EUR): 2478210.0
Participants: 1
Project status: SIGNED

Our project aims to revolutionize the water industry through the development and commercialization of an innovative robotic inspection system. Our robotic inspection system offers a comprehensive set of functionalities that enable water utilities to gain deep insights into the condition of their water pipelines. With the ability to autonomously navigate inside the pipeline, our system conducts detailed assessments of the structural integrity, identifies leaks, and analyses the quality of the drinking water. By developing the Digital Twin of the water networks, our technology empowers water utilities to make informed decisions and take proactive measures to ensure the reliability, efficiency, and safety of their water networks. At the core of our business model is Robotics as a Service (RaaS), which offers a flexible and cost-effective solution for water utilities. Instead of incurring substantial upfront costs, water utilities can access our cutting-edge technology on a subscription basis. This model eliminates the financial barriers to entry and allows utilities to benefit from the latest advancements in robotic inspection without compromising their budgetary constraints. With a strong focus on sustainability, our robotic inspection system aligns with several Sustainable Development Goals (SDGs), including SDG 6 (Clean Water and Sanitation) and SDG 9 (Industry, Innovation, and Infrastructure). During 2025-2029, our robotic inspection system will preserve 143 million cubic metres of drinking water; these savings correspond to the annual consumption of 2.6 million EU citizens. This greatly aligns with global efforts for sustainable water management and environmental preservation.

Keywords: water pipeline inspection,digital twin,non destructive testing,in line robotic inspection system,non revenue water
Recycling process trains of waste bioplastics (Sus-Bio-plastics)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Cyprus
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-02, 2022)
Start date: 2022-11-01
End date: 2025-03-31
Duration (months): 29.0
Total project cost (EUR): 164328.0
EU funding (EUR): 164328.0
Participants: 1
Project status: CLOSED

The objective of Sus-Bio-plastics is to develop new biotechnological waste-to-value chains for the most promising (based on market share value) bioplastics by implementing innovative microbially mediated practices. To achieve this aim, the project is structured under 3 innovation pillars, regarding 2 processes and 1 tool for integrating sustainability in waste management of bioplastics (1 non-biodegradable (bio-PE) and 3 biodegradable (PLA, PHB and TPS)). Microalgal-bacterial or bacterial communities will be exploited as a biotechnological tool to formulate a stable metapopulation capable of degrading bioplastics. In case mechanical recycling is considered as the best end-of-life option, a bioclean-up process of the weathered layer of the bioplastics PLA and bio-PE will be developed. This process will serve as a pretreatment stage prior to mechanical recycling which will yield near virgin pellets holding the capacity to enter the recycling stream. In case organic recycling is the best end-of-life option, a new bio-recycling route will be developed to treat waste biodegradable bioplastics (PHB and TPS) and produce high-value compounds. The mutualistic interplay between microalgal and bacterial species will be capitalized towards bioplastics upcycling and minimization of CO2 releases, constituting a highly novel approach which has not been previously explored.

Keywords: bioplastics,microalgae,recycling
Novel macrodiolide Immunosuppressants (MACROMUNO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-05-01
End date: 2026-10-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Several major unmet medical needs, such as autoimmune disorders and neuroinflammatory conditions, are characterized by aberrant Type-1 interferon production, suggesting that new drugs that specifically target this central inflammatory signalling axis could provide significant value for patients and for society. In this project, we will develop the foundation for future commercial exploitation of a class of novel macrocyclic immunosuppressants which has been shown to possess unprecedented broad inhibitory activities against several innate immunological pathways that converge on the transcription factor IRF3 linked to interferon production. Based on diverse preliminary data that span both cellular biology and chemical synthesis strategies, the planned work is aimed at securing a strong IP-position by providing novel structure-activity relation data on relevant cellular activities linked to IRF3-activity. The project will proceed to identify potential compound leads with favourable pharmacokinetic properties to be pushed forward for future in vivo experiments. The primary focus will be on ability to permeate the blood-brain-barrier (to address major neuroinflammatory conditions) and on achieving good plasma stability. Alongside the concrete experimental tasks and strengthening of the IP-position, a broader business plan and associated funding strategy will be prepared. This involves engagement of key future stakeholders and establishment of an advisory board. Overall, the planned activities serve to make the project ready for a pre-seed investment or acceptance into an biotech-accelerator program following completion of the ERC-PoC project.
Circadian rHythms and theiR associatiON with myOPIA (CHRONOPIA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Estonia,United States
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-06-01
End date: 2027-05-31
Duration (months): 36.0
Total project cost (EUR): 278435.04
EU funding (EUR): 278435.04
Participants: 2
Project status: SIGNED

Myopia or short-sightedness is a refractive error caused by excessive eyeball elongation, resulting in distant objects appearing blurry. Its global prevalence is increasing rapidly and is estimated to affect half of the global population by 2050. Several recent studies have suggested a link between circadian rhythms and eye development. An analysis at the Estonian Biobank revealed a robust association between myopia and an individual’s sleep timing preference, or chronotype. Individuals with late chronotype were more likely to have myopia, while early chronotype was associated with hyperopia. This project, CHRONOPIA, aims to uncover the underlying mechanisms and directionality of this relationship. It seeks to understand how circadian rhythms influence eye growth and how refractive errors, in turn, impact circadian rhythms. The effect of circadian rhythms on refractive development will be studied in mice by employing various circadian biology paradigms with simultaneous monitoring of refractive development. The impact of refractive errors on circadian rhythms will be evaluated using the mouse model of lens-induced myopia and hyperopia, circadian phenotyping techniques, retinal transcriptomics, and ex vivo assessment of retinal circadian rhythms. Finally, through genome-wide gene-based association studies, this project will analyse the molecular similarities between the mouse model of myopia and human myopia. This provides an opportunity to discover novel genes and pathways associated with human myopia and to determine how well the mouse model of the disease models human myopia on a molecular level. By elucidating the interactions between refractive errors and circadian rhythms, we aspire to contribute valuable insights into the molecular mechanisms that could guide the development of innovative preventive and therapeutic strategies to address the escalating myopia epidemic.

Keywords: myopia refractive errors circadian rhythms mouse model of disease