Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Training a new generation of researchers in offshore seaweed aquaculture to produce high-value chemicals (SEACHEM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Belgium,Ireland,United Kingdom,Spain,France,Denmark,Netherlands,Portugal,Sweden
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2022-10-01
End date: 2026-09-30
Duration (months): 48.0
Total project cost (EUR): 2891576.01
EU funding (EUR): 2768795.44
Participants: 18
Project status: SIGNED

SeaChem will provide high-level R&D training for early-stage researchers in the emerging field of marine biomass production. By addressing hot issues in offshore seaweed cultivation and its application as a source of renewables, Seachem will take away current hurdles for its wide adoption in the EU. Concurrently, the interdisciplinary SeaChem network (composed of academia, industry and sector organisations) and the variety of scientific disciplines integrated into the SeaChem R&D scheme, guarantees a multidisciplinary formation of the 10 next-generation highly-trained doctoral candidates. The main SeaChem R&D objectives are indeed spread over construction engineering (development of stainless steel offshore structures), biology (optimal conditions for seaweed cultivation) and chemical engineering (intensified extraction of valuable compounds). By the combination of state-of-the-art research topics with multiple transferrable and social skills training events, SeaChem will ensure the broad scientific and personal development of the doctoral candidates. The high societal and economic relevance of this field is supported by the ever increasing societal pressure for the development of renewable resources, also relieving the dependency of the EU on imported (fossil) raw materials. The growing worldwide market in renewable and sustainable products is driving this economic sector and is already creating a large need of highly-skilled professionals, hence ensuring a myriad of job opportunities for the doctoral candidates.

Keywords: seaweed,stainless steel structures,chemical extraction,enzymatic extraction,life cycle assessment
SEAWATER HYDRAULIC PTO USING DYNAMIC PASSIVE CONTROLLER FOR WAVE ENERGY CONVERTERS (SHY)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Denmark,Spain,Ireland,Austria,Netherlands,Germany,United Kingdom
Call: Development of innovative power take-off and control systems for wave energy devices (HORIZON-CL5-2023-D3-02, 2023)
Start date: 2024-04-01
End date: 2027-03-31
Duration (months): 36.0
Total project cost (EUR): 4857988.48
EU funding (EUR): 3811110.32
Participants: 10
Project status: SIGNED

The SHY project will develop a composite linear pump and controller valve that use seawater as the working fluid and enable the use of a dynamic passive controller to maximise the power capture. A dynamic passive controller involves the dynamic control of active energy, i.e. only damping forces. This has been shown to provide a significant increase in power capture relative to optimum linear damping without the requirement to provide additional reactive energy. The performance of this control strategy and associated technologies will be proven by applying it to the Wavepiston wave energy converter; however, it is expected to be equally suitable for a wide range of wave energy converters that utilise a hydraulic PTO. A numerical model of the system will be constructed and used to develop a control strategy designed to minimise the levelized cost of energy, rather than maximise power capture, which is a common, but sub-optimal, objective for many control strategies. The control strategy will first be calibrated and validated using a hardware-in-the-loop test programme and subsequently validated using the Wavepiston offshore test bench at PLOCAN. Two generations of the linear pump and controller valve will be fabricated, designed for mass production with consideration of its full lifecycle impacts (although the actual prototypes may use low volume techniques to limit project costs). The second generation prototypes will be based on learning from experiences and the performance of the first generation. A condition controller designed to increase the remaining useful life and thus reduce the LCOE will also be investigated. This will include identifying condition signatures that indicate a deterioration in one or more components and then using this signature to first estimate the remaining useful life followed by identification of modifications to the control strategy to extend the remaining useful life.

Keywords: wave energy
High-Power Optical Vortices – From Generation to Application (HiPOVor)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Finland,Germany,Poland,United Kingdom,Romania,Belgium,France,Lithuania
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 4400280.0
EU funding (EUR): 4400280.0
Participants: 20
Project status: SIGNED

The use of high-power optical vortex beams has been predicted to provide substantial benefits to many applications ranging from more precise material processing to advanced particles accelerators. However, progress has been hampered by the absence of approaches for their generation while maintaining their unique properties during propagation and/or interaction with matters. The overall aim of HiPOVor is to train 15 ESRs to be the first generation of a workforce skilled in all aspects concerning the generation of optical vortices with high power and high modal purity and its application as a key enabling technology widely in light-matter interaction aspects. Through the completion of interconnected individual projects in topics all together covering the full development chain, ranging from components suitable for their generation and fundamental aspects of their physical properties, to amplification, propagation in different environments and applications, the doctoral candidates will develop expert skills and knowledge to drive forward the field of high-power optical vortices. The HiPOVor network will address gaps both in terms of technology and applications, and in terms of personnel through the innovative research approaches. The interdisciplinary and intersectoral consortium consists of 8 leading academic institutions in the field of structured light and high-power laser development, the world’s most powerful laser infrastructure ELI-NP, as well as 9 industrial partners, highlighting the high potential of and interest in our project for rapid market uptake. The results of our project promise significant impacts in strengthening Europe’s scientific excellence. It will enable new products and improved processes, e.g. optical components and nanofabrication, and environmental benefits through building of a circular economy, reduction of harmful chemical, and reduction of size and power cost of hardware via advanced technologies predicting by high power vortices.

Keywords: optical vortices,orbital angular momentum,structured light,high power lasers,light matter interaction
Probabilistic decision framework for Resilience assessment of Offshore energy infrastructures subjected to seismic Submarine landsLIDE hazard (PRO-SLIDE) (PRO-SLIDE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark,Hong Kong,Australia
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-12-01
End date: 2025-11-30
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 3
Project status: SIGNED

The offshore energy infrastructure (OEI)-soil interaction has been studied by numerical analyses in the literature. However, these studies are rarely focused on the performance of OEIs during the seismic submarine landslide (SSL). Moreover, the pseudo-static approach employed for stability assessment of OEI is generally conservative for deep water conditions. The dynamic approach needs a wide range of input parameters and spends a lot of time and money on analyses. Accordingly, predictive models are needed to fill the gap between these approaches for a simple prediction of OEI deformations during SSL. The overall objective of PRO-SLIDE is to develop a reliable and low computational cost solution for simplified resilience assessment of OEIs damage due to SSLs. Answering this concern is not trivial, but it can guide future analyses and contribute to gaining insights from a calibration effort using numerical models that will be undertaken using a benchmark centrifuge model that can successfully capture key mechanisms and features as well as trends. The findings will be based on a database produced via advanced numerical analyses of the OEI-SSL mechanism using the DEM-FEM, a catalog of near-fault ground motions, machine learning technic, and probabilistic/fragility analyses. A two-way transfer of knowledge is guaranteed since I have a solid background in the development of earthquake-induced sliding models and ground motions databank and also my supervisor at AAU has vast experience in the resilience assessment of OEIs and data-driven models. Moreover, my supervisors at secondments (RMIT&HKUST) have great experience in the fields of OEI numerical simulation and physical modeling. Accordingly, this will ensure the achievement of this timely and innovative project as well as the dissemination and exploitation of the expected results. The acquired skills will allow me to embrace an academic/non-academic career path in the EU.

Keywords: offshore energy infrastructure,earthquake,landslide,deformation predictive model,fragility function,resilience assessment
Loop Corrections from the Theory of Motives (LoCoMotive)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 1999878.0
EU funding (EUR): 1999878.0
Participants: 1
Project status: SIGNED

The interactions between the elementary particles are encoded into a set of mathematical quantities called scattering amplitudes. Consequently, they are key to making predictions for physical observables that match the precision achieved by current and future high-energy experiments. Due to our ignore of the mathematics involved, computing loop quantum corrections to scattering amplitudes is still a major challenge today, and calls for innovative and groundbreaking new techniques. Over the last decade, a new field of research that studies scattering amplitudes through the lens of a certain branch of modern mathematics, the so-called theory of motives, has led to breakthroughs in how we compute loop quantum corrections. LoCoMotive will bring the connection between scattering amplitudes and modern mathematics to the next level. It will investigate in detail what the theory of motives teaches us about the structure of scattering amplitudes. Its final aim is to achieve a global change of perspective on the mathematical underpinnings of the laws of nature and develop novel computational techniques for scattering amplitudes that are currently beyond reach of conventional state-of-the-art technology. Inspired by cutting-edge research in seemingly-disconnected areas in mathematics and physics, LoCoMotive will 1) perform the computations needed to reveal how concepts from geometry govern the fundamental interactions. 2) play a decisive role in providing the theoretical predictions needed for the LHC and future collider experiments. 3) act as a catalyser for new research in mathematics. To sum up, LoCoMotive is a timely proposal with a unique multi-disciplinary character, whose results will bridge a gap between formal theory and concrete phenomenological results. It will have a major impact on formal aspects of quantum field theory and possibly even pure mathematics, and provide highly-needed theoretical predictions for the LHC experiments.

Keywords: scattering amplitudes,feynman integrals,lhc
Smart digital solutions for multimodal, accessible, resilient, user-centric urban infrastructure (SMARTIN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Safe, Resilient Transport and Smart Mobility services for passengers and goods
Action type: Innovation actions
Countries involved: Belgium,Spain,Hungary,Greece,Italy,Latvia,Denmark
Call: Improved transport infrastructure performance – Innovative digital tools and solutions to monitor and improve the management and operation of transport infrastructure (HORIZON-CL5-2024-D6-01, 2024)
Start date: 2025-07-01
End date: 2028-06-30
Duration (months): 36.0
Total project cost (EUR): 5533125.0
EU funding (EUR): 4999725.0
Participants: 17
Project status: SIGNED

Innovative digital tools and solutions have the potential to significantly upgrade transport infrastructure, enhancing performance, safety, and inclusiveness while reducing emissions. Digital solutions are crucial for minimizing traffic disruptions, boosting transport efficiency, and decreasing reliance on fossil fuels. The SMARTIN project aims to revolutionize the management of transport infrastructure through advanced digitalization and intelligent, data-driven solutions. SMARTIN is developing a connectivity platform where transport infrastructure assets are digitalized, and mobility optimization services operate harmoniously. Advanced AI-driven analytics are being developed to fuse infrastructure monitoring data at different geospatial resolutions, enabling proactive incident detection and supporting infrastructure providers and users in operations and maintenance management. These innovations are integrated into the overarching operational architecture of the SMARTIN digital infrastructure. The SMARTIN platform architecture will revolutionize infrastructure governance by improving the operation and management of urban transport infrastructure and redesigning transport and mobility activities for all stakeholders. SMARTIN's innovations will be demonstrated across four representative European cities, showcasing their potential to enhance infrastructure accessibility and resilience, promote multimodality, and accelerate the adoption of digital solutions.

Keywords: infrastructure digitalization performance assessment multimodal transport data driven solutions predictive maintenance infrastructure monitoring,resilience and robustness urban infrastructure
DANIO-CODE - the next frontier: Decoding transcription regulation in regeneration by advanced genomics and computational tools (DANIO-ReCODE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain,United Kingdom,Slovenia,Sweden,Austria,Germany,Croatia
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 2901493.03
EU funding (EUR): 2785636.8
Participants: 20
Project status: SIGNED

The principal objective of DANIO-ReCODE is to provide world-class doctoral training to a new generation of early-career researchers interested in understanding the complex and multilayered process of tissue regeneration. DANIO-ReCODE will combine the multidisciplinary expertise of 15 research laboratories at renowned EU and UK scientific institutions to unravel the regulatory mechanisms of heart, brain, and eye regeneration by employing the unique and highly tractable zebrafish model system. Unlike humans, teleosts can repair damaged tissues or even regrow entire appendages. In mammals, regeneration is rare, limited to skin, liver, and toes. Regenerative medicine, however, promises to restore tissue function via the use of stem cells, tissue engineering, and the production of artificial organs, with its importance being recognised as one of the EU strategic missions. A fundamental gap of knowledge is the understanding of the shared and distinct regulatory mechanisms defining regeneration in highly regenerative species and those with lower regeneration potential such as mammals. Since the vertebrate gene complement is highly conserved, applying the knowledge of regeneration mechanisms from non-mammalian models such as zebrafish could identify genetic underpinnings, which when manipulated in mammals, could strongly boost the mammalian regenerative potential. DANIO-ReCODE will thus nurture a cohort of exceptional doctoral candidates and turn them into interdisciplinary experts in computational and developmental biology, providing comprehensive training that spans experimental work, bioinformatics, visualisation, and industry applications. Through the integration of state-of-the-art genomics, computational, and data visualisation techniques, DANIO-ReCODE will result in an enhanced understanding of molecular determinants implicated in vertebrate regenerative processes while providing new avenues for the repair or replacement of damaged or diseased tissues and organs.

Keywords: regeneration injury response
Mitochondrial one-carbon metabolism as a therapeutic target in reducing cancer metastasis (Target-C1)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Luxembourg
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 216240.0
EU funding (EUR): 216240.0
Participants: 1
Project status: SIGNED

The key research goal of the MSCA PF is to enhance the leadership and research capability of the fellow Laura Martínez via implementing a multidisciplinary and innovative research project focused on targeting mitochondrial one-carbon metabolism and formate overflow to prevent the pro-invasive effect induced by this metabolite. The understanding of the specific metabolic dependencies involved in the metastatic cascade remains a challenging endeavor in cancer therapy since metastasis is the most common cause of death in cancer patients. In this sense, in the receiving group it has been recently demonstrated that mitochondrial one-carbon (1C) metabolism, which leads to formate overflow, plays a pivotal growth-independent role in promoting tumor cell invasiveness. However, effective strategies targeting this mitochondrial pathway have not yet been elucidated. Consequently, this proposal aims to further explore the promising role of 1C metabolism in cancer progression with the final goal to establish new strategies targeting formate overflow, potentially paving the way for the development of new anti-cancer therapies. The specific objectives are (1) preventing formate accumulation inducing formate degradation by gene-therapy approaches and (2) using melatonin as a therapeutic agent to inhibit formate production. This project will be carried out at Luxembourg Institute of Health and supervised by Dr. Johannes Meiser, a recognized expert in Cancer Metabolism. The experience of the applicant in melatonin and gene-therapy research, together with the recognized expertise of the host group in metabolomic will lead to the proper project achievement. This MSCA PF will provide the applicant with advanced technical training in metabolomic, the core expertise of the host lab, and cytometry, as well as self-reliant project management, leadership and mentoring skills, increasing Laura future opportunities towards becoming an autonomous researcher specialized on Cancer Metabolism.

Keywords: metabolism anticancer therapy genetic engineering
Tracing Evolutionary Pathways in Grassroots Climate Governance: Connecting Past, Present, and Future Inter-Scalar Adaptation Strategies in Southeast Asia (TRACE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Netherlands
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

TRACE aims to amplify grassroots forces in climate governance to spearhead systematic transformations and just transitions. It pushes for a paradigm shift in climate governance, with Southeast Asia as a key site to adaptation strategies. Through reframing and reconceptualization of climate adaptation as geographies of knowledge, culture, and agency, TRACE will develop groundbreaking transdisciplinary concepts, frameworks, research methodologies, and tools for knowledge co-creation, power co-production, and agency shaping in climate governance. TRACE centrally puts co-creation of knowledge, co-production of power and culture, and agency as key praxis in climate adaptation and climate governance. It highlights the need to decipher past knowledge on adaptation and connects these with present and future adaptation strategies through archival, oral history and ethnographic research. It looks at evolutionary pathways of local institutions, their institutional arrangements, and adaptation practices as key building blocks for holistic, inclusive, and just climate governance. TRACE unpacks the underlying plural knowledge systems (e.g. traditional local knowledge, technological interventions) that inform ever-changing adaptation practices of farmers’, foresters’ and fishermen’s families across spatio-temporal scales, and vice versa. Climate adaptation as geographies of knowledge, culture, and agency is contextually rooted in four distinct yet interrelated socio-ecological systems across Southeast Asia. This is a region with diverse socio-ecological systems and wide range of knowledge systems, where grassroots forces in climate governance are present and hold great potential for the formation of inter-scalar climate adaptation networks. These socio-ecological systems are: 1) upland cultivation in Laos; 2) irrigated agriculture in Indonesia; 3) forest conservation in the Thai-Myanmar borderlands; and 4) sea nomads’ fishing territories in the Philippines.