Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Coastal Waters Research Synergy Framework (Co-ReSyF)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: Research and Innovation actions
Countries involved: Ireland,Italy,France,United Kingdom,Portugal,United Kingdom
Call: Stimulating wider research use of Copernicus Sentinel Data (H2020-EO-2015, 2015)
Start date: 2016-01-01
End date: 2018-12-31
Duration (months): 36.0
Total project cost (EUR): 2999901.25
EU funding (EUR): 2999901.25
Participants: 9
Project status: CLOSED

The Co-ReSyF project will implement a dedicated data access and processing infrastructure, with automated tools, methods and standards to support research applications using Earth Observation (EO) data for monitoring of Coastal Waters, leveraging on the components deployed SenSyF. The main objective is to facilitate the access to Earth Observation data and pre-processing tools to the research community, towards the future provision of future Coastal Waters services based on EO data. Through Co-ReSyF‘s collaborative front end, even young and/or inexperienced researchers in EO will be able to upload their applications to the system to compose and configure processing chains for easy deployment on the cloud infrastructure. They will be able to accelerate the development of high-performing applications taking full advantage of the scalability of resources available in the cloud framework. The included facilities and tools, optimized for distributed processing, include EO data access catalogue, discovery and retrieval tools, as well as a number of pre-processing and toolboxes for manipulating EO data. Advanced users will also be able to go further and take full control of the processing chains and algorithms by having access to the cloud back-end and to further optimize their applications for fast deployment for big data access and processing. The Co-ReSyF capabilities will be supported and initially demonstrated by a series of early adopters that will develop new research applications on the coastal domain, will guide the definition of requirements and serve as system beta testers. A competitive call will be issued within the project to further demonstrate and promote the usage of the Co-ReSyF release. These pioneering researchers in will be given access not only to the platform itself, but also to extensive training material on the system and also on Coastal Waters research themes, as well as to the project's events, including the Summer School and Final Workshop.

Keywords: cloud computing,big data,earth observation,services,coastal waters research
Mechanisms and regulators coordinating replication integrity and DNA damage tolerance. (REPSUMODDT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Italy
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-07-01
End date: 2021-12-31
Duration (months): 66.0
Total project cost (EUR): 1991250.0
EU funding (EUR): 1991250.0
Participants: 1
Project status: CLOSED

Accurate chromosomal DNA replication is of fundamental importance for cellular function, genome integrity and development. In response to replication perturbations, DNA damage response (DDR) and DNA damage tolerance (DDT) pathways become activated and are crucial for detection and tolerance of lesions, as well as for facilitating replication completion and supporting chromosome structural integrity. While important functions and key players of these regulatory processes have been outlined, much less is known about the choreography and mechanistic interplay between DDR and DDT during replication. Moreover, the principles by which they uniquely or commonly affect replication-associated chromosome integrity remain poorly understood. Here, we will use novel tools and a palette of ingenious genetic, molecular and proteomic based experimental strategies, to investigate the replication stress response triggered by diverse endogenous and exogenous cues, and to identify the underlying mechanisms. We will define the principles of local and temporal regulation of DDT in response to genotoxic stress, with a focus on the mechanisms of SUMO-regulated DNA metabolism processes. Additionally, we will investigate the topological DNA transitions triggered at intrinsically difficult to replicate genomic regions, stalled and terminal forks, with the aim of identifying key mechanisms and regulators of replication integrity at specific complex genomic regions or following specific types of replication stress. Finally, we will explore the relationship between DDT, replication fork architecture and sister chromatid cohesion in the context of DDR- and SUMO-orchestrated DNA transactions. We expect that these studies will reveal new aspects of how replication-associated DNA metabolism processes are inter-related and regulated, uniformly or at specific loci in the genome, and will break new ground in areas of replication mechanisms and chromosome integrity in general.

Keywords: dna replication,sumo,dna damage tolerance,sister chromatid cohesion,dna damage response
Cryptophane-Enhanced Trace Gas Spectroscopy for On-Chip Methane Detection (sCENT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Norway
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-01-01
End date: 2024-12-31
Duration (months): 84.0
Total project cost (EUR): 1499749.0
EU funding (EUR): 1499749.0
Participants: 1
Project status: SIGNED

Sensitivity of on-chip gas sensors is still at least 2-3 orders of magnitude lower than what is needed for applications in atmospheric monitoring and climate research. For optical sensors, this comes as a natural consequence of miniaturization: sensitivity scales with interaction length, which is directly related to instrument size. The aim of this project is to explore a new concept of combined chemical and spectroscopic detection for on-chip sensing of methane, the principal component of natural gas and a potent climate forcer. The sought-after sensitivity will be achieved by pre-concentrating gas molecules directly on a chip surface using cryptophanes, and subsequently detecting them using slow-light waveguides and mid-infrared laser absorption spectroscopy. Cryptophanes are macromolecular structures that can bind and thus pre-concentrate different small molecules, including methane. Spectroscopic detection of methane in a cryptophane host is an absolute novelty, and, if successful, it will not only contribute to unprecedented sensitivity enhancement, but will also address fundamental questions about the dynamics of small molecules upon encapsulation. The actual gas sensing will be realized using evanescent field interaction in photonic crystal waveguides, which exhibit both large evanescent field confinement and long effective interaction pathlengths due to the slow-light effect. The waveguide design alone is expected to improve the per-length sensitivity up to 10 times, while another 10 to 100-fold sensitivity enhancement is expected from the pre-concentration. The targeted detection limit of 10 ppb will revolutionize current methods of atmospheric monitoring, enabling large-scale networks of integrated sensors for better quantification of global methane emissions. Beyond that, this method can be extended to the detection of other gases, e.g. CO2 and different volatile organic compounds with equally relevant applications in the medical domain.

Keywords: mid infrared spectroscopy,photonic crystals,slow light enhancement,cryptophanes,methane,sensing
Secure and Safe Internet of Things (SerIoT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Germany,Spain,Austria,Spain,Spain,Spain,Cyprus,Greece,Belgium,Greece,Poland,United Kingdom
Call: R&I on IoT integration and platforms (H2020-IOT-2017, 2017)
Start date: 2018-01-01
End date: 2021-04-30
Duration (months): 40.0
Total project cost (EUR): 4999083.75
EU funding (EUR): 4999083.75
Participants: 18
Project status: CLOSED

The IoT is coming upon us faster than we think, catapulting EU industry, homes and society into the huge arena of security risks that accompany an untested yet already universal technology that directly manages our cyber-physical reality on a daily, and indeed second by second, basis. Attacks on content and quality of service of the IoT platforms can have economic, energetic and physical security consequences that go way beyond the traditional Internet’s claimed lack of security, and beyond the threats posed by attacks to mobile telephony. The secure SerIoT platform is a key step that can be used to implement secure IoT platforms and networks anywhere and everywhere. The SerIoT project will develop, implement and test a generic IoT framework based on an adaptive smart Software Defined Network with verified software, secure routers, advanced analytics, and user friendly visual analytics. SerIoT will optimize the information security in IoT platforms and networks in a holistic, cross-layered manner (i.e. IoT platforms & devices, honeypots, SDN routers and operator’s controller) that will be based both on dynamic and distributed processing of variable complexity by single network components (i.e. IoT platforms, devices and honeypots will perform lightweighted processes while SDN routers will be shouldered with more heavy processes), as well as on a centrally located server/controller that will have the main control of the network and will collect, aggregate and fuse the relevant information. Large-scale pilots will test SerIoT technology in various use cases including intelligent transport and surveillance, flexible manufacturing within Industrie 4.0 and other emerging domains such as food chain & logistics, m-Health (both at Home & in Hospitals business scenarios) and energy (smart grid).Through these technology developments and test-beds, the project will deliver a unique portable software-based SerIoT network that can spearhead Europe’s success in the IoT.

Keywords: iot safe and secure ecosystem,secure iot router,sdn for iot,cross layer anomaly detection,design driven iot security,blockchain,va for attack prevention,root cause analysis and mitigation,ad hoc io
Talent4BBI: Developing Talent for Bio-Based Industries of Europe (Talent4BBI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Doctoral programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Ireland
Call: Co-funding of regional, national and international programmes (H2020-MSCA-COFUND-2020, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 2386560.0
EU funding (EUR): 1193280.0
Participants: 1
Project status: SIGNED

Cutting-edge PhD training in bio-based industries is a critical necessity to tackle the challenges, risks and strategic opportunities of the rapidly evolving European bioeconomy. Talent4BBI will provide a unique opportunity for Early Stage Researchers to develop key skills, competencies and experience required by bio-based industries through a targeted programme for future bioeconomy leaders. Coordinated by BiOrbic Bioeconomy SFI Research Centre at University College Dublin (Ireland) over a 60-month programme duration, 11 ESRs will undertake PhDs of 48 months cohosted by academia and industry. ESRs will be recruited and co-hosted by a consortium of 16 partners across 8 Member States and 1 Associated Country (7 universities and 9 leading bio-based industries) with a wealth of collective experience in training talented mobile researchers. 3 additional partners will contribute their expertise to the training programme. In line with the principles set out in the Charter and Code and with the EU Principles for Innovative Doctoral Training, a unique practice-based pedagogy will enable graduates to thrive in an industrial and academic research setting and enhance ESR career opportunities in line with the MSCA COFUND work programme objectives. Talent4BBI’s selection process will be guided by principles of openness, transparency, merit, impartiality and equality for the ESRs. Talent4BBI will impact the European Research Area through developing a uniquely qualified and career-driven talent pool, driving effective cooperation between industry and academia, and boosting the development of bio-based industries.

Keywords: bio based industries,bioeconomy
European-Japanese Virtual Coach for Smart Ageing (e-VITA)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Germany,Germany,Germany,Germany,Germany,Belgium,France,France,France,Japan
Call: International cooperation in smart living environments for ageing people (H2020-SC1-DTH-2020-1, 2020)
Start date: 2021-01-01
End date: 2024-03-31
Duration (months): 39.0
Total project cost (EUR): 4515897.0
EU funding (EUR): 3998220.0
Participants: 13
Project status: SIGNED

Background: Virtual coaching can play an important role in sustaining Active and Healthy Ageing (AHA) through early risk detection and tailored intervention in smart living environments. However, current technologies are not easily customized to individual needs, provide limited interaction, and are often intrusive. Aims and Relevance: Based on an excellent international cooperation between Europe and Japan, e-VITA proposes an innovative approach to virtual coaching that addresses the crucial domains of AHA: cognition, physical activity, mobility, mood, social interaction, leisure, and spirituality, thus empowering older adults to better manage their own health and daily activities, resulting in improved well-being and improved stakeholder collaboration. The e-VITA virtual coach will provide individualized profiling and personalized recommendations based on big data analytics and social-emotional computing beyond the state-of-the-art. Approach: The virtual coach will detect preventative potentials and risks in the user’s daily living environment by collecting data from external sources and non-intrusive sensors and will provide support through natural interactions with 3D-holograms, emotional objects, or robotic technologies using multimodal and spoken dialogue technology, advanced knowledge graph representations and data fusion. Interoperability and data privacy will be guaranteed using FIWARE and a federated data AI platform. Proof of concept: A support system will be provided to enable the elderly users to learn and use the virtual coaching system. The coaching system will be deployed and evaluated in the living environments of healthy older adults in France, Germany, Italy, and Japan to assess its feasibility and efficacy. The results of e-VITA include also new standards and policies beyond technology, and will be consequently exploited and transferred across Europe, Japan and worldwide.

Keywords: healthy ageing,personalized services,human computer interaction
Ultimate Angular Resolution Astrophysics with kernel-phase and full-aperture interferometry (KERNEL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: France
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-10-01
End date: 2022-03-31
Duration (months): 66.0
Total project cost (EUR): 1717811.0
EU funding (EUR): 1717811.0
Participants: 1
Project status: CLOSED

Astronomy requires large telescopes to improve the sensitivity and the angular resolution of its observations. Of these qualities, angular resolution is the most difficult to maintain in the optical and near-infrared, since the atmosphere reduces it to that of a 10 cm aperture, regardless of the telescope size. On the one-hand, Adaptive Optics (AO) actively compensates for this effect but the improvement is often partial only. On the other hand, interferometric techniques (most notably sparse aperture masking interferometry) passively allow the extraction of self-calibrating observables, that boost the angular resolution, but severely affect the sensitivity of observations. A framework newly established by the PI of the proposal however now makes it possible to extract generalized self-calibrating observables called kernel-phases from conventional AO-corrected images. The work outlined in this proposal will make it possible to scientifically exploit the high angular resolution imaging capability of this technique, to improve its robustness and to expand its capabilities. The framework offers a very general purpose high angular resolution imaging tool for astronomers as well as wavefront control experts. This proposal is organized in five work-packages of increasing challenge that include: the reinterpretation of existing archival data with a super-resolution capability, the expansion of its robustness to open up new more challenging use-cases, a special focus on the development of a very high-dynamic range mode, the adaptation of interferometric image reconstruction techniques, and the development of new advanced AO concepts. The consequences of this project will have a major impact on the design and scientific exploitation of future high angular resolution instrumentation on the existing generation of 8-10 meter class telescopes as well as on the upcoming generation of 30-40 meter giants, championned by Europe and its E-ELT.

Keywords: interferometry,high contrast imaging,extrasolar planets,low mass stars,brown dwarfs
Do behaving animals extract information from precise spike timing? – The use of temporal codes (Temporal Coding)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Israel
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-01-01
End date: 2021-06-30
Duration (months): 66.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: CLOSED

Neural temporal codes have come to dominate our way of thinking on how information is coded in the brain. When precise spike timing is found to carry information, the neural code is defined as a temporal code. In spite of the importance of temporal codes, whether behaving animals actually use this type of coding is still an unresolved question. To date studying temporal codes was technically impossible due to the inability to manipulate spike timing in behaving animals. However, very recent developments in optogenetics solved this problem. Despite these modern tools, this key question is very difficult to resolve in mammals, because the meaning of manipulating a part of a neural circuit without knowledge of the neural activity of all the neurons involved in the coding is unclear. The fly is an ideal model system to study temporal codes because its small number of neurons allows for complete mapping of the neural activity of all the neurons involved. Since temporal codes are suggested to be involved in olfactory intensity coding, I will study this process. I will device a multidisciplinary approach of electrophysiology, two-photon imaging and behavior. I aim to examine for the first time directly whether temporal coding is used by behaving animals and to unravel the circuits and mechanisms that underlie intensity coding. To do so, I will manipulate the temporal codes in behaving animals and examine whether the behavioral responses change accordingly. To guide this study I will generate three novel databases of: i. the temporal activity of all neurons involved in Drosophila olfactory intensity coding. ii. The functional connectivity between the two brain regions that are involved in the intensity coding and iii. behavioral responses to different odors and intensities. Thus, this research will use cutting edge techniques to resolve a long standing basic question in neuroscience: how does the brain actually code information?

Keywords: temporal coding,drosophila,olfaction,intensity coding,optogenetics
A sub-percent distance scale from binaries and Cepheids (CepBin)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Poland,France,Chile
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-11-01
End date: 2021-10-31
Duration (months): 60.0
Total project cost (EUR): 2360500.0
EU funding (EUR): 1351225.0
Participants: 4
Project status: CLOSED

We propose to carry out a project which will produce a decisive step towards improving the accuracy of the Hubble constant as determined from the Cepheid-SN Ia method to 1%, by using 28 extremely rare eclipsing binary systems in the LMC which offer the potential to determine their distances to 1%. To achieve this accuracy we will reduce the main error in the binary method by interferometric angular diameter measurements of a sample of red clump stars which resemble the stars in our binary systems. We will check on our calibration with similar binary systems close enough to determine their orbits from interferometry. We already showed the feasibility of our method which yielded the best-ever distance determination to the LMC of 2.2% from 8 such binary systems. With 28 systems and the improved angular diameter calibration we will push the LMC distance uncertainty down to 1% which will allow to set the zero point of the Cepheid PL relation with the same accuracy using the large available LMC Cepheid sample. We will determine the metallicity effect on Cepheid luminosities by a) determining a 2% distance to the more metal-poor SMC with our binary method, and by b) measuring the distances to LMC and SMC with an improved Baade-Wesselink (BW) method. We will achieve this improvement by analyzing 9 unique Cepheids in eclipsing binaries in the LMC our group has discovered which allow factor- of-ten improvements in the determination of all basic physical parameters of Cepheids. These studies will also increase our confidence in the Cepheid-based H0 determination. Our project bears strong synergy to the Gaia mission by providing the best checks on possible systematic uncertainties on Gaia parallaxes with 200 binary systems whose distances we will measure to 1-2%. We will provide two unique tools for 1-3 % distance determinations to individual objects in a volume of 1 Mpc, being competitive to Gaia already at a distance of 1 kpc from the Sun.

Keywords: eclipsing binaries,cepheids,distance scale