Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Advanced platfoRm for ClimAte Data Intelligence and Action (ARCADIA)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Spain
Call: Boosting the potential of small businesses in the areas of climate action, environment, resource efficiency and raw materials (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-02-01
End date: 2018-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Vizzuality (Simbiotica, S.L.) is a Spanish company widely known in the environmental sector for creating accessible open data projects and web tools aimed to analyse datasets and images interrelated, with the aim to create beautiful visualizations able both to raise awareness on a variety of issues related to life on Earth, and also to ease scientific research with a focus on environmental topics, a business that will yield the company more than €4 million turnover in 2017. From its foundation in 2009, the company has been working on a regular basis with institutions of such relevance as the World Resources Institute and the United Nations to help them understand information inside Big Data in issues relevant for the studies they perform. The business opportunity to be seized by this project lies in the concern lately raised on climate change in the light of recent environmental disasters. Vizzuality owns a leading technology to make meaningful the large volumes of environmental data extracted from Earth observation in the form of powerful visualizations, a technology of high interest for knowledge purveyors, but scarcely used by societal end-users such as SMEs, which represent 99% of the European business realm. This strategic project aims to make that technology available for the private sector (especially SMEs) through a software platform for freemium access, a new business model for the company which would need a feasibility study to confirm expectations laid on it, and then a stronger business plan to face a successful market uptake based in this new model, since it shapes a financial challenge likely to introduce a new way to earn incomes for the company while contributing to the creation of a European market for climate services. Vizzuality’s business performance since its inception evidences its potential to achieve such a challenge, at the same time it addresses a business opportunity aligned with the interests of the EU in terms of climate change mitigatio

Keywords: climate services,data visualization,earth observation,environmental awareness,risks assessment,climate change mitigation
Engineering catalyst interoperability in next-generation tandem reactions for intensified chemical processes (TANDEng)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Spain
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-06-01
End date: 2025-05-31
Duration (months): 60.0
Total project cost (EUR): 1982188.0
EU funding (EUR): 1982188.0
Participants: 1
Project status: SIGNED

Process intensification and catalysis are considered key stepping-stones towards a future sustainable chemical industry. Potentially, a major intensification can be achieved by the integration of two catalysts in a single reactor, to steer sequential chemical reactions in a tandem fashion. Yet, tandem catalytic processes face a notorious barrier towards industrial realization: the challenge of harmonizing the rates at which the integrated catalysts individually process and collectively exchange molecules, to avoid e.g. derivation of intermediate products through undesired reaction pathways, something elegantly achieved in nature's enzymatic tandem reactions via complex substrate channelling phenomena. TANDEng is set to break through this frontier limitation via an effort which encompasses aspects of chemistry, material science, physics and reaction engineering. The challenge is to tackle the current constraining dichotomy that close proximity of tandem catalysts, which is mandatory for an efficient transport of intermediate products between their active sites, prohibits individual adjustment of other key performance parameters such as temperature. To break through this paradigm, the project seeks to realize a disengaged engineering of the chemical and thermal "intimacies" in tandem solid catalysts. Fundamental studies will guide the development of innovative catalysts featuring i) bespoke porosities for fast molecular transport, able to mimic a nanoscale proximity even for active sites residing in different macroscopic particles, and ii) implanted ancillary functions designed to achieve a catalyst-specific heating and thermometry in compact reactors with unconventional electromagnetic power supply. The novel concept will be validated to unlock currently unfeasible tandem processes to address the timely challenge of valorising delocalized feedstocks, alternative to petroleum (unconventional gas and biomass), where process intensification is an enabling prerequi
The travelling astronomers. International collaborations after World War II and the reorganization of European astronomy (1953-1985) (ISHTAR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-01
End date: 2017-05-31
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

This research project investigates the history of astronomy in Europe after World War II. In the period between 1953 and 1985, a number of international collaborations were undertaken by several European countries, with the aim of strengthening astronomical research in terms of its capacity and facilities. These collaborations culminated in the construction of powerful observational facilities and the implementation of programmes for cooperation in professional research. In this respect, the initiatives taken from 1953 to 1985 inaugurated a new era of European astronomy. Indeed, in this period research facilities were made available in both hemispheres, new research networks were created, and there was a new attitude towards scientific cooperation. This study will analyse crucial aspects of the development of astronomy in post-war Europe. More specifically, this research will address the interactions among astronomers, scientific institutions, and governments in the light of the quest of new astronomical sites; the connections between scientific, technical, political, and economic issues in the foundation of new astronomical observatories; and the changes in the community of professional astronomers, both in terms of research practice and social organization. Consequently, this study will contribute to elucidate the reorganization of astronomy in post-war Europe. Moreover, it will reinforce the comprehension of the development of scientific research, science policy and international scientific cooperation.

Keywords: history of astronomy,astronomical observatories,science in post war europe,science policy,international cooperation,cold war science
Strengthening European Food Chain Sustainability by Quality and Procurement Policy (Strength2Food)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Italy,Italy,Germany,Italy,Spain,Belgium,Hungary,Norway,Serbia,Greece,Croatia,Poland,Thailand,Serbia,France,France,France,Netherlands,United Kingdom,Viet Nam,United Kingdom,United Kingdom
Call: Sustainable food chains through public policies: the cases of the EU quality policy and of public sector food procurement (H2020-SFS-2015-2, 2015)
Start date: 2016-03-01
End date: 2021-05-31
Duration (months): 63.0
Total project cost (EUR): 6911876.25
EU funding (EUR): 6904226.25
Participants: 33
Project status: CLOSED

Strength2Food is a 5-year, €6.9 million project to improve the effectiveness of EU food quality schemes (FQS), public sector food procurement (PSFP) and to stimulate Short Food Supply Chains (SFSC) through research, innovation and demonstration activities. Our 30-partner consortium representing 11 EU and 4 non-EU countries combines leading academic, communication, SME and stakeholder organisations to ensure a multi-actor approach. It will undertake case study-based quantitative research to measure economic, environmental and social impacts of FQS, PSFP and SFSC. The impact of PSFP policies on balanced nutrition in schools will also be assessed. Primary research will be complemented by advanced econometric analysis of existing datasets to determine impacts of FQS and SFSC participation on farm performance and survival, as well as understand price transmission and trade patterns. Consumer knowledge, confidence in, valuation and use of FQS labels and products will be assessed via cross-national survey, ethnographic and virtual supermarket-based research. Lessons from the research will be applied and verified in 6 pilot initiatives, focusing on less-developed and transition regions. These initiatives bring together academic and non-academic stakeholder partners in action research. The six pilot actions are: a school meals initiative to improve the nutritional outcomes and economic benefits for local agri-food producers; in-store trials (undertaken with a grocery retailer) to upscale sales of local produce; a scheme to stimulate a sustainable SFSC that adds value to the fishing community; and pilot actions to expand regional food labelling; increase sales of FQS products in non-traditional markers; and improve returns to local producers at food fairs and farmers’ markets (via a smartphone app). Project impact will be maximised through a knowledge exchange platform, hybrid forums, school educational resources, a Massive Open Online Course and practitioner recommendations.

Keywords: short food supply chains,organic,public procurement,school meals,rural development
GOethite in Supergene Systems: ANalysing trace element substitution goethite and related iron oxides and oxyhydroxides. (GOSSAN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

The GOSSAN project will provide a full and accurate study on the geochemical, morphological and structural composition of iron oxides and oxyhydroxide compounds, The attention will be focalized on goethite in different types of Supergene Ore deposits (SOD). More precisely, it is aimed to investigate the concentration, structural position and cationic exchange and economic potential of goethite as an unconventional source of “Critical Elements” (CE). Furthermore, the behaviour of the the goethite precursor phase (ferrihydrite) will be documented by assessment of the ions behaviour during maturation and transformation to goethite and finally hematite. The project will be developed in two years in which the reseacher will examine the mineralogy and geochemistry of many supergene samples of the NHM collections by the useof the analytical facilities provided by NHM. Ion exchange reactions will be assessed by experimental tests while the geochemical uptake of metallic trace elements will be studied by the use of TEM and Synchrotone XAS techniques. Furthermore, metallurgical treatments will be carried out on selected natural metal-bearing goethite specimens from different SOD in order to study the potential recovery of the metals trapped in the structure to assess the economic potential of iron oxides and oxyhdroxides The project also comprises a well-defined plan of training activities for the researcher in order to enhance its skills and help him to develop its future career as researcher.

Keywords: goethite,ferryhdrite,oxhydroxide compounds,ion exchange,mineral deportment,critical elements
Socioeconomic gaps in language development and school achievement: Mechanisms of inequality and opportunity (EQOP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Norway
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-06-01
End date: 2025-05-31
Duration (months): 72.0
Total project cost (EUR): 1907959.0
EU funding (EUR): 1692671.06
Participants: 3
Project status: SIGNED

As inequality increases in most developed countries, children from socioeconomically disadvantaged families are at exceptional risk for academic underachievement with lasting consequences for individuals, their communities, and society at large. Among policy makes, early childhood education and care (ECEC) is considered a key to remedy this risk. Yet the science on ECEC effectiveness at a national scale lags behind the excitement. Exploiting unique Norwegian data, we first seek to identify how and why socioeconomic disadvantage undermines children’s language skills and school achievement. Second, we will investigate whether ECEC can improve opportunities for disadvantaged children to excel. Third, to clarify the policy relevance of these inquiries, we will estimate costs of socioeconomic achievement gaps and the economic benefits of ECEC at scale. We take an investigative approach that is unprecedented in scope—from population level trends down to nuanced assessments of individual children’s growth. Throughout the 2000s, Norway’s child poverty rates increased from about 4% to 10%, while the coverage of public ECEC for toddlers increased from 30% to 80%. Across this unique window of time, we have access to rich survey data on language skills and home environment for 100,000 children, and genetically informative data, linked with administrative records on community- and family level socioeconomic risks and opportunities, and on national achievement test scores. These data allow us powerful analytic opportunities, combining state-of-the-art statistical, econometric, psychometric, and genetic epidemiological methods. I am well positioned to lead this project, having qualified for a Professorship at the University of Oslo aged 36, and having considerable experience in (a) publishing in highly respected scientific journals, (b) working at the intersection of research and policy, (c) leading research projects, and (d) mentoring younger scholars.

Keywords: social inequality,language development,school achievement,early childhood care and education,family processes,home environment,neighborhood,benefit cost analyses
Well-Confined Mucosal LasEr Ablation with a Negative Pressure Based Endoscopy Capsule (CLEAN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Türkiye
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-04-01
End date: 2021-03-31
Duration (months): 24.0
Total project cost (EUR): 157355.52
EU funding (EUR): 157355.52
Participants: 1
Project status: CLOSED

This proposal is an interdisciplinary research action. The objective of the CLEAN project is to develop a novel endoscopic capsule design and to build a prototype endoscopy system using this capsule, which provides local ablation to the superficial layer of target mucosal tissue with sufficient depth to remove abnormal tissue. However, this depth will be shallow enough to avoid the residual effects of therapy within deeper tissue layers. The specific aims are: Aim-1: To develop a computer modelling to mimic the thermal dynamics of the capsule. It is to characterize the total heat energy needed to successfully ablate the lining layer, an adequate sliding speed along the oesophagus, an adequate therapy time for effective thermal target layer ablation, and the amount of thermal injury induced to the various oesophagus layers. Aim-2: To develop the configuration of the capsule in a computer-aided design program. This original design simply extends the target layer above and away from its underlying layers to achieve a well-confined therapeutic effect by delivering vacuum force. With the confinement of therapeutic effect, it is aimed that deeper tissue structures are partially separated from ablation region. Aim-3: To construct and optimize a prototype-level endoscopy system for pre-clinical ex-vivo tissue trials. A high power, 1380-nm diode laser will be used for the therapeutic photothermal ablation. Aim-4: To investigate the feasibility of the design and to evaluate the performance of the prototype system in ex-vivo sheep oesophagus model. Tissue samples will be collected for histology examination to validate the performance goals of the device.

Keywords: optical endoscopy,photothermal ablation,device development,barrett s oesophagus
Molecular, Structural, and Functional Studies of Leukemia-Associated Transcription Factor-Nucleoporin Fusion Proteins (TFNup)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 174806.4
EU funding (EUR): 174806.4
Participants: 1
Project status: SIGNED

Nup98 is a mobile nucleoporin that localizes both at the nuclear pore complex and within the nucleus. Nup98 is frequently rearranged to form leukemogenic Nup98-fusion proteins with various partners. Nup98-HoxA9 (NHA9), a fusion between phenylalanine-glycine-rich (FG-rich) region of Nup98 and the homeobox transcription factor (TF) HoxA9, is one of the most frequent Nup98-fusion associated with acute myeloid leukemia. The physiological role of NHA9 in hematopoietic development has been gradually established in the past decade at the cellular level. However, the plasticity and the phase separation behavior of such intrinsically disordered proteins (IDPs) largely hinder our understanding of their functions in gene regulation at the molecular level. In this project, I will develop platform technologies that combine chemical biology, microfluidics, and high-resolved molecular imaging to study the structure and biophysical function of NHA9 in vitro and in cells, and open up a new pathway to unravel its role in gene dysregulation from molecular perspective. Firstly, I will dual-label NHA9 at specific sites using the cutting-edge genetic code expansion technology developed by the host laboratory, and characterize the plasticity of NHA9 in live cells using Fluorescence lifetime imaging (FLIM) based Förster resonance energy transfer (FRET) platform. Next, I will use my strengths in microfluidics to design a new platform for tracking the phase separation behaviors of NHA9 with high temporal resolution in vitro. Finally, I will fuse NHA9 with proximity-dependent biotin identification (BioID) tags, and visualize the dynamic interaction networks of NHA9 using super-resolution microscopy (SRM) in live cells. By integrating those interdisciplinary approaches, the proposed research would make a conceptual breakthrough in understanding the molecular mechanism of NHA9-driven leukemogenesis and may provide a rationale for the search of potential therapeutic approaches in the future.

Keywords: intrinsically disordered protein,phase separation,single molecule detection,chemical biology,microfluidics
INTEGRATED COMMON ALTITUDE REFERENCE SYSTEM FOR U-SPACE (ICARUS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Italy,Italy,Spain,Italy,Italy,Belgium,Poland
Call: U-space (H2020-SESAR-2019-2, 2019)
Start date: 2020-05-01
End date: 2022-07-31
Duration (months): 27.0
Total project cost (EUR): 1385286.25
EU funding (EUR): 1144587.5
Participants: 9
Project status: CLOSED

ICARUS project proposes an innovative solution to the challenge of the Common Altitude Reference inside VLL airspaces with the definition of a new U-space service and its validation in a real operational environment. In manned aviation, the methods of determining the altitude of an aircraft are based on pressure altitude difference measurements (e.g. QFE, QNH and FL) referred to a common datum. The UA flights superimpose a new challenge, since a small drone may take off and land almost from everywhere, hence reducing the original significance of QFE settings, introduced on behalf of manned pilots to display on the altimeter the 0-height at touchdown on the local runway. In fact, the possibility for n drones to take off at n different places would generate a series of n different QFE corresponding to different heights of ground pressures referred to the take-off “Home points”. Therefore for a large number drones, new methodologies and procedures shall be put in place. The ICARUS defines a new U-space U3 service tightly coupled with the interface of the existing U-space services (e.g. Tracking, and Flight Planning services). The users of ICARUS service shall be remote pilots competent to fly in BVLOS in the specific category of UAS operations and ultralight GA pilots potentially sharing the same VLL airspace. The ICARUS proposed approach foresees the realization of DTM service embedded in an Application Program Interface (API) that can be queried by UAS pilot/operator (or by drone itself) based on the actual positioning of the UA along its trajectory, computed by the (E)GNSS receiver. The output of the DTM service would provide information on distance from ground/obstacles in combination with the common altitude reference. Accuracy, continuity, integrity and availability requirements for GNSS-based altimetry together with accuracy and resolution requirements of the DTM to be provided by ICARUS service are key topics of the study.

Keywords: height systems and frames,gnss,cars