Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The Silk Road Language Web: A linguistic prehistory of the Tarim Basin in Northwest China (SilkRoadLanguageWeb)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1999863.0
EU funding (EUR): 1999863.0
Participants: 1
Project status: SIGNED

On the crossroads between China, India and the Eurasian Steppes, the Tarim Basin in present-day Northwest China was a crucial part of the famous Silk Road trading network. Today, the main languages of the area are Uyghur and Mandarin, but numerous manuscript finds are proof of a past rich in entirely different languages. Next to literary languages like Sanskrit, the local vernaculars were Middle Indic, Tocharian, and the Iranian languages Khotanese and Tumšuqese. All Indo-European and hailing ultimately from the west, these languages show the effects of intricate patterns of long-term influence, thus forming a network of linguistic contact: the Silk Road Language Web. The interpretation of this intriguing linguistic complex has been dominated by the narrative that the Tocharians are to be identified with the Bronze Age “Tarim Mummies”, to the detriment of other groups. However, in concordance with genetic evidence, the linguistic findings of the PI’s ERC-Starting Grant and NWO-VIDI projects show that the Tocharians arrived much later, while the Iranians arrived earlier and spread over a larger area than previously assumed. Thus, an entirely new approach to the linguistic past of the Tarim Basin is called for. Based on the evidence from long-term language contact contained in the Silk Road Language Web, this project will unravel the linguistic past of the Tarim Basin to make a groundbreaking contribution to the linguistic and migrational prehistory of Eurasia. Reconstructing the dates of the splits and spreads of Khotanese, Tumšuqese and Tocharian, it will establish their routes and dates of entry into the Tarim Basin. Further, Khotanese and Tocharian vocabulary of unclear origin will be scrutinised for traces of languages of the earlier Bronze Age populations. Finally, the linguistic developments will be followed into historical times, tracing how the attested languages were eventually shaped by the later formative impact of Middle Indic and Middle Iranian.

Keywords: historical linguistics linguistic prehistory language contact indo european tarim basin
Drug Trafficking and Politics: Structuring and Adaptation of Organized Crime in Bolivia's Last Authoritarian Decade (1971-1982) (NARCOPOLITICS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States,Bolivia, Plurinational State of
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2028-04-30
Duration (months): 35.0
Total project cost (EUR): 384484.02
EU funding (EUR): 384484.02
Participants: 3
Project status: SIGNED

NARCOPOLITICS aims to enhance our understanding of the global dynamics linking drug trafficking and political power through the case study of Bolivia between 1971 and 1982. During this period, Bolivia became a pivotal player in drug trafficking due to its extensive coca plantations, the Santa Ana cartel led by Roberto Suarez Gómez, and persistent ties between drug smugglers and political institutions ruled by the military, aligned with the National Security Doctrine. Adopting a long-term historical perspective and considering organized crime as a significant Cold War non-state actor, NARCOPOLITICS has three objectives: examining the role of drug traffickers in Bolivia's political developments and their adaptability to changes in the national and regional context; identifying the political conditions under which the Santa Ana cartel intersected with political and ideological spheres and assessing the consequences; and analyzing and comparing measures—both official and unofficial including operations of security agencies—taken by the three US administrations during this period, examining the long-term impact of the “war on drugs.” The research methodology combines recently opened archival documents and judiciary sources from different countries, providing a comprehensive narrative and analysis. This approach aims to address issues such as difficulty in identifying involved actors and ensuring data reliability. The rise of state-narco networks in countries like Mexico, Guinea-Bissau and Afghanistan highlights the urgent need for comprehensive research and policy responses. Understanding the historical context and evolution of drug-influenced states, as exemplified by Bolivia's experience, can provide critical insights into addressing these modern challenges. The Fellowship will benefit my career prospects, equipping me with new skills, knowledge, and specialized training, placing me at the forefront of my field as an established interdisciplinary researcher.

Keywords: drug trafficking and politics latin american cold war organized crime transnational anti communism military dictatorships war on drugs
Myopia - from genes and environment to cellular responses and treatment (MyoTreat)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Norway,United Kingdom,Netherlands,Austria,France,Switzerland
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2023-12-01
End date: 2028-05-31
Duration (months): 54.0
Total project cost (EUR): 2971062.51
EU funding (EUR): 2747743.2
Participants: 12
Project status: SIGNED

In modern industrial societies, myopia has become an important ocular health problem of young people, due to its increased incidence and associated complications, which pose a significant risk of blindness already in the middle life span. Current treatment options have limited effects with a maximum reduction of axial elongation by about 0.4 mm over several years, equivalent to a reduction in myopia by only about 1 D. Eye growth is controlled by an interplay of different biochemical pathways, one inhibitory (stimulated by image plane in front of the retina) and one stimulatory (image plane behind the retina). A novel future strategy would be to activate the inhibitory pathways rather than inhibit the growth stimulating pathways (standard target in most studies). At present, interventions to activate growth inhibition are poorly studied. The influence of environmental factors (spectral composition of ambient light) and gene-environment interactions (specific gene variants and their interaction with key lifestyle exposures) on eye growth and refractive development will be investigated. New pharmacological targets will be identified and tested, and biomarkers established to detect the onset of myopia at an earlier stage. It will be studied how choroidal hypoxia relates to choroidal thinning and axial eye growth and how it interacts with the metabolic processes in the retina and sclera. New measurement techniques will be developed that implement artificial intelligence algorithms to improve diagnostics in myopia studies, especially in the periphery of the visual field. The proposed intersectorial and interdisciplinary "MyoTreat" project (including anatomy, physiology, pharmacology, optics, and genetics) will train PhD students in myopia research and generate and disseminate novel research results. The ultimate scientific goal is to identify new strategies for myopia therapy through hypothesis-driven translational research in various animal models as well as in humans.

Keywords: myopia,gene environment interaction,defocus detection,pathway analysis,hypoxia,choroid
charting Immunological Maps of Populations Across Complex disease and lifetime Trajectories (IMPACT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Integrative B iology : from Genes and Genomes to S ystems
Panel description: For all organis ms: Genetics, epigenetics, genomics  and other ‘omics studies , bioinformatics, systems biology , genetic diseases , gene editing, innovative methods and modelling,  ‘omics for personalised  medicine
Countries involved: Italy,United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2025-12-01
End date: 2030-11-30
Duration (months): 60.0
Total project cost (EUR): 2499998.0
EU funding (EUR): 2499998.0
Participants: 2
Project status: SIGNED

The extending human lifespan and its associated accumulation of morbidities due to chronic disorders calls for new models to accelerate the early detection, prognosis and treatment of chronic conditions. To date, anchoring detailed molecular knowledge of disease processes with diagnoses of chronic diseases from ‘real-world’ biomedical data remains an open challenge.The immune system plays a central role in human health and survival, while deterioration of immune function is implicated in the development of many devastating chronic conditions. While many aspects of immune functions have been studied in exquisite molecular detail, we still lack a comprehensive understanding of how lifestyle factors, environmental exposures and biology contribute to deterioration of immune functions during the human life-course, and consequently to risk of disease as individuals age. With this project we propose a new research paradigm to study chronic human diseases by combining the power of single-cell technologies with multimodal information of health states and genomics derived in large-scale population settings. In Objective 1, we will use state of the art statistical modelling on a world-unique dataset of 12M peripheral blood mononuclear cells (PBMCs) generated by my group. We will combine immunological states with data from health records to discover cell states associated with markers of normal ageing processes, diverse disease diagnoses and environmental exposures. In Objective 2, we will use multimodal profiling and ex vivo experiments to validate genes and networks associated with disease-relevant cell state variation. In Objective 3, we will apply this new knowledge to predict the long-term risk of disease in diverse population settings. Overall, this project promises to add a fundamental new perspective to our understanding of the dynamic changes of the immune system over the human adult lifecourse, and its interaction with health and disease states.

Keywords: causal inference single cell biomedical records health data genetics population studies age related chronic diseases disease prevention cellular programmes gene networks
Spin systems with discrete and continuous symmetry: topological defects, Bayesian statistics, quenched disorder and random fields (Vortex)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: France,Chile
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1616250.0
EU funding (EUR): 1616250.0
Participants: 3
Project status: SIGNED

The main goal of this project is to understand the geometry of the deeply influential topological phase transitions which were discovered in the 70's by Berezinskii, Kosterlitz and Thouless. The archetypal example of such phase transitions arises in the 2d XY model in which topological defects, called vortices, behave very differently at small and high temperature. The mathematical understanding of this rich phenomenon goes back to the work of Fröhlich and Spencer in the 80's and involves the 2d Coulomb gas. This project is aimed at analyzing this phase transition through the prism of random fractal geometry by associating natural percolating sets to the XY model whose behavior will depend crucially on the temperature. One constant source of inspiration will be the deep geometric content and powerful probabilistic methods gathered over the last 20 years for celebrated discrete symmetry models such as 2d critical Ising or percolation. New tools will be brought in, among which the recent works of the PI with Sepúlveda which analyze the 2d Coulomb gas and make connections with Bayesian statistics. Since the early days of topological phase transitions, topological defects have been found to arise also in some discrete symmetry spin systems as well as in Abelian lattice gauge theory in 4d. This project will explore the geometry of these by making several novel and fruitful connections with the dimer and Ising models. The new connections made with statistical reconstruction and Bayesian statistics will give access to the even more fascinating and least understood world of spin systems with non-Abelian (gauge-)symmetry. Finally, we shall investigate the mechanisms which relate the microscopic background noise with the large scale structures it induces in the contexts of Quantum Field Theory and KPZ fixed point. The impact of this project will go well beyond the current understanding of topological phase transitions in a wide variety of settings where they arise.

Keywords: kosterlitz thouless transition,coulomb gas,xy model,lattice gauge theory,gaussian free field,discrete beta ensembles,kpz fixed point,ising model,critical percolation,dynamical percolation,noise sensitivity,planar statistical physics
Determinants of island ecological complexity in the context of global change (IslandLife)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Environmental B iology, Ecology  and E volution
Panel description: For all organisms : Ecology, biodiversity, environmental change , evolutionary biology, behavioural ecology, microbial ecology , marine biology, ecophysiology, theoretical developments and mod elling
Countries involved: Spain
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-11-01
End date: 2027-10-31
Duration (months): 60.0
Total project cost (EUR): 2483723.75
EU funding (EUR): 2483723.75
Participants: 1
Project status: SIGNED

Biodiversity is declining globally at an unprecedented rate. Representing ~30% of the biodiversity hotspots, islands are particularly vulnerable to anthropogenic activities, indeed 80% of reported extinctions are island species. Yet, unique island biodiversity – which includes not only the species but also the myriad of interactions among them – is still greatly unknown. It is thus urgent to describe it and forecast the consequences of its annihilation so we can mitigate the effect of further losses. Detecting ecological interactions and understanding their complexity is, however, one of the big challenges in the natural sciences. The advent of new theories and analytical tools, such as critical transition theory and complex network analysis, provides hope to reach that goal. As relatively simple systems with well-defined borders, islands have a great potential to advance our comprehension of nature complexity. IslandLife will provide the most comprehensive and quantitatively sophisticated study of multilayer networks to date in any terrestrial ecosystem. We will focus on five archipelagos encompassing four oceans and a wide latitudinal gradient, comparing for the first time the food web structure of ‘pristine’ (little-disturbed) islands (of a few km2) with areas of similar size in nearby disturbed (human-inhabited) islands. The objective is to unveil the unique biodiversity of these ecosystems, understand their complexity, and evaluate their fragility to global change drivers, such as biological invasions. We will combine direct observations during intense fieldwork, automated-video monitoring and deep-learning, cutting-edge molecular techniques, and newly developed coextinction models to predict persistence and resilience of island biota to disturbances. The project will represent a major breakthrough towards understanding the effects of global change on these valuable ecosystems, of great relevance to both theoretical ecologists and applied conservationists.

Keywords: ecological complexity island ecology food webs multilayer networks species interactions biological invasions disturbance metabarcoding automated video monitoring computer vision deep learning coextinction models network reassembly habitat restoration
Art in border practice and policy (BORDERART)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-16
End date: 2026-04-15
Duration (months): 30.0
Total project cost (EUR): 199440.96
EU funding (EUR): 199440.96
Participants: 1
Project status: SIGNED

The project’s main objective is to build a framework examining how artistic practice can be applied within migration policy contexts. Addressing calls by refugees, asylum seekers and human rights organisations for more humane approaches to policy, this framework will specifically investigate how artworks made in response to the EU migration crisis can raise awareness, build understanding or disrupt usual relationships between refugees, local long-term residents, NGOs and border security personnel. Developed within a comparative study between Greece and Tunisia, the project will reflect the impact of the EU’s current retracting and expanding borders in two key sites on either side of the Mediterranean sea. As the EU enacts ‘buffer zones’ to stem the arrival of asylum seekers on mainland Europe, art practices will be analysed for the ways in which they express and alleviate multiple stresses for those impacted by such policy. Beginning with a review of artistic practices on site in these two locations, the project will map and analyse how art reveals relationships between multiple actors across refugee, resident, NGO and border personnel communities. This review will be contextualised by a wider review of art in global border practices. Interviews with key informants and observations of different practices in Greece and Tunisia will then inform the development of a practice as research methodology, drawing on the ER’s own arts practice to co-create a series of artworks with local actors to test and map possibilities for new and different relationships between those enacting and those impacted by migration policy. This participatory arts practice will iterate through a regular co-evaluation process to a build a framework that reflects the role of art in relation to multi-stakeholder support, partnership building and ethical approaches to inter-personal relationships. The framework and its development will be made available on an interactive website.

Keywords: borders migration ethnography performance studies relational aesthetics practice as research feminist cultural studies human rights conflict resolution
Fourier-Domain TRx solutions enabling widespread realisation of 6G (FirstTo6G)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Smart Networks and Services
Action type: Research and Innovation actions
Partnership: SNS (JU-JTI)
Countries involved: Germany,Sweden,Greece,Türkiye,Switzerland
Call: Microelectronics-based Solutions for 6G Networks (HORIZON-JU-SNS-2023, 2023)
Start date: 2024-01-01
End date: 2027-06-30
Duration (months): 42.0
Total project cost (EUR): 5373340.0
EU funding (EUR): 4999894.0
Participants: 6
Project status: SIGNED

FirstTo6G assembles European SMEs and leading universities to develop the globally first 6G TRx technology, i.e., data converters and corresponding sub-THz frontends, which fulfils the extreme requirements for making 6G a widespread reality. These requirements include extremely wide modulation bandwidth at high signal quality, high energy efficiency, and low cost. Using a novel breakthrough microchip architecture, we will develop data converters with up to 16 GHz of modulation bandwidth, with extremely low power consumption, which are implemented in a commercial, low-cost 22nm semiconductor technology. We will also develop state-of-the-art frontend technology and integrate both parts to two full TRx solutions with unprecedented capabilities. The TRx for the frequencies <100 GHz will deliver 8 GHz of modulation bandwidth and will be realised in a monolithically integrated chip. The TRx for the frequency range of 130-175 GHz will deliver 16 GHz of modulation bandwidth and will integrate on PCB the data converters and the SiGe frontends using advanced packaging technologies. The D-band frontend will be designed based on a fully automated design flow. Key exploitable FirstTo6G results include designs for new technical concepts for data converters and the frontend, integration of high-performance TRx components in a single chip and automation algorithms for the design of frontends. We will use these results to develop and directly commercialise high performance mm-wave / early 6G products, as a basis for further research, or to spin-off new businesses. By making the widespread realisation of 6G possible, we will enable the highly positive contribution to prosperity of society which 6G will ultimately have. Critical technical knowledge will be developed and exploited in Europe by strongly growing SMEs, which will grow the communication microelectronics provider landscape, bolster the European microelectronics ecosystem and strengthen European technological sovereignty

Keywords: 6g trx,fourier domain,8 ghz modulation bandwidth,57 ghz frequency,16 ghz modulation bandwidth,100 ghz frequency,integrated trx in 22fdx,sige,analogue design automation