Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Disease and vaccine monitoring based on non-invasive genital tract liquid biopsy sampling. (URISAMP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-05-01
End date: 2027-04-30
Duration (months): 60.0
Total project cost (EUR): 1499265.0
EU funding (EUR): 1499265.0
Participants: 1
Project status: SIGNED

The ability to easily obtain appropriate and reliable biological samples is critical to advance life sciences and public/personal health. Having a sample that is non-invasive and can be self-collected at home has major acceptance and feasibility advantages. Our team demonstrated that first-void urine (FVU) samples can replace clinician collected cervical samples to prevent cervical cancer caused by the Human Papilloma virus (HPV). Using the initial or first void urine stream is crucial here. Indeed, the outer layers of the epithelium of the genital tract exfoliate and together with the genital mucus form the utero-cervico-vaginal-smear, it accumulates between the labia minora, around the urethral opening and upon initiation of urination this discharge is washed away with the FVU. URISAMP uses HPV infection and vaccination models to prove the hypothesis that FVU is the ideal liquid genital tract biopsy to monitor immune response for women. URISAMP will 1) identify and validate analytical methods to detect the relatively low and fluctuating concentration of potential biomarkers in FVU; 2) provide protocols to study neutralizing antibodies and look at antigen-antibody interaction; 3) demonstrate how FVU sampling can enhance our knowledge regarding the biology of HPV, genital tract immunology, mechanisms of infection and transmission, the biological basis of prevention and potential correlates of protection. URISAMP will contribute to simplify and facilitate sexually transmitted infection (STI) vaccine research and provide valuable data for disease modelling. Moreover, if URISAMP proves successful, and FVU can also replace other samples types (e.g.blood), applications will largely extend the STI field, and its impact as a novel diagnostic and prognostic tool for health assessment will be substantial.

Keywords: self sample,non invasive,human papilloma virus,vaccination,monitoring
Improving Cement-based Infrastructure from Nanoscale Grounds (ICING)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-04-01
End date: 2028-03-31
Duration (months): 24.0
Total project cost (EUR): 242260.56
EU funding (EUR): 242260.56
Participants: 1
Project status: SIGNED

This project addresses the pressing need for sustainable and durable concrete infrastructure by investigating the degradation mechanisms of cement paste (the binder phase of concrete) materials at the atomic level. Leveraging advanced atomistic simulations, we will focus on the chemo-poro-mechanical properties of cement paste to provide a fundamental understanding of how environmental factors and material composition influence material degradation processes including freeze-thaw, carbonation, alkali-silica reaction, and accelerated decalcification in saline solution, based on which effective mitigation strategies such as compositional optimisation, molecular structure design, and surface modification will be developed to enhance the long-term durability of cementitious infrastructure, contributing to a reduction in the carbon footprint of the construction industry. The project will employ a multidisciplinary approach combining computational modelling, experimental validation, and material development. The project outcomes will directly contribute to the Work Programme's objectives by: 1. Advancing global scientific knowledge in the field of sustainable construction materials. 2. Developing innovative solutions for enhancing the lifespan of cement-based infrastructure and reducing the environmental impact of the construction industry. 3. Fostering collaboration between academia and industry to accelerate the adoption of sustainable construction practices. This project will contribute to a more sustainable and resilient built environment by providing the scientific basis for the development of next-generation concrete technologies.

Keywords: atomistic simulations cementitious materials degradation infrastructure resilience
Sustainable Peri-Urban framework for Climate Neutral development (SpurUP)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Climate neutral and smart cities
Destination: Climate neutral and smart cities
Action type: Innovation actions
Countries involved: Greece,Italy,Netherlands,Romania,United Kingdom,Ireland,Sweden,Cyprus,Estonia,Bulgaria,Denmark
Call: Integrated peri-urban areas in the transition towards climate neutrality (HORIZON-MISS-2024-CIT-01, 2024)
Start date: 2026-01-01
End date: 2029-04-30
Duration (months): 40.0
Total project cost (EUR): 10919103.75
EU funding (EUR): 8996414.5
Participants: 34
Project status: SIGNED

The SpurUP project brings together 34 partners from 11 EU countries, including universities and research institutions, technology providers, local authorities, industries and NGOs. This diverse and experienced team will work together to create resilient, climate-neutral peri-urban regions that enhance the sustainability and well-being of communities, addressing the challenges under the domains of industry and governance. SpurUP aims to integrate net-zero technologies and foster participatory governance to tackle environmental pressures and fragmented governance in these regions. The project will establish Local Green Deals (LGDs) to unite public and private sectors in reducing greenhouse gas (GHG) emissions, improving energy efficiency, and promoting social equity and sustainability. Implemented through 3 Living Labs in Thessaloniki, Greece; Aalborg, Denmark; and Jesi, Italy, SpurUP will test innovative technologies and digital tools tailored to each region's needs. Key objectives include decarbonization, circular economy practices, and enhanced governance and stakeholder engagement. Additionally, 3 replication sites in Stara Zagora, Bulgaria; Tulcea, Romania; and Bristol, UK will further demonstrate the scalability and adaptability of the solutions. SpurUP aims to significantly reduce GHG emissions, improve energy efficiency, and increase the deployment of renewable energy technologies. The project will promote sustainable industrial practices and better integrate peri-urban areas into planning processes. The project employs a three-tier strategy to maximize impact and scalability. The first tier involves testing and validating solutions in the Living Labs. The second tier engages an external group of stakeholders, including regional and local authorities, to provide feedback and validate the solutions. The third tier focuses on scaling and replicating successful solutions across additional regions and local authorities in Europe and globally.

Keywords: peri urban,climate neutrality,industry,governance,sustainability
CMPSR: Making Music Accessible and Fun for Everyone Through Innovative Gaming Technology (CMPSR Rhythm)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 18.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Digit Music is transforming music and gaming with CMPSR (Computer Music Performance, Sequencing, and Recording), a technology that simplifies music creation through intuitive interfaces. Our award-winning hardware, CMPSR: Move, and touchscreen software, CMPSR: Swipe, make music creation accessible to everyone, including those with disabilities. Our objectives, democratise music creation, innovate mobile music gaming, and promote inclusivity. We aim to empower users to create and share music without specialised training. By developing a mobile music rhythm game that integrates melody and harmony, users can progress from casual play to skilled musicianship. Our technology is designed to be usable by individuals of all abilities, fostering an inclusive creative environment. We achieve this by using EIC funding to advance CMPSR from TRL6 to TRL8, incorporating advanced features for a robust user experience. We will develop and launch a mobile music rhythm game offering in-app training, royalty-free content, and a platform for user-generated music. And foster a community through social gaming and sharing user-generated content, creating a supportive environment for musical growth. Aligning with Horizon Europe EIC Accelerator by promoting breakthrough technologies that drive societal impact. CMPSR introduces a novel approach to music creation and gaming, bridging the gap between casual users and professional musicians. It provides accessible music-making tools for a diverse audience promoting social inclusion and equality. Supporting the creative industries, vital for economic development, it generates new products and services that enable growth. By making music creation accessible, engaging, and inclusive, CMPSR transforms the creative landscape, promoting mental well-being, economic growth, and environmental sustainability. With EIC’s support, we will bring this disruptive innovation to market, positioning Digit Music as a leader in the music gaming industry.

Keywords: music performance,accessibility,inclusive design,music creation,rhythm game,social gaming,trl advancement,creative industries,economic impact,mental well being,sustainability
From cell shape to organism shape: the cellular basis for the evolutionary origin of animal morphogenesis (EvoMorphoCell)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cell Biology, Development, Stem Cells and R egeneration
Panel description: For all organisms : Structure and function of the cell, cell -cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-08-01
End date: 2027-07-31
Duration (months): 60.0
Total project cost (EUR): 1492753.0
EU funding (EUR): 1492753.0
Participants: 1
Project status: SIGNED

My work concerns a critical question: How did the cellular mechanisms underpinning animal morphogenesis first evolve? While the first multicellular ancestors of modern animals have left limited fossil traces, insights can be gained by studying their closest living relatives: the choanoflagellates. This group of microeukaryotes has several features of high relevance to animal origins, including temporal cell differentiation, facultative multicellularity, and a metazoan-like "developmental gene toolkit". Importantly, they have become amenable to functional genetics in the past few years. We will study the molecular and cellular mechanisms of three morphogenetic processes in choanoflagellates: (1) the formation of the "collar complex", a ring of microvilli surrounding the flagellum, which represents an example of complex single-cell morphogenesis and has been central to hypotheses about animal origins; (2) the molecular control of the differentiation of choanoflagellates into amoeboid cells under confinement, which I recently discovered and whose mechanisms remain unknown; (3) the cellular basis of adhesion and inversion in sheet colonies of the multicellular species Choanoeca flexa which I recently co-discovered. These three processes will be characterized by multiomic approaches which will allow unbiased comparisons with the growing dataset of molecular atlases for animal cell types. We will perform knockout, chemical inhibition, and fluorescent tagging of candidate genes identified by omics and/or known to play important roles in animals, including structural genes (such as those encoding cytoskeletal and adhesion proteins) and components of signalling pathways. Results will be analyzed in a rigorous phylogenetic framework. This project has the potential to answer long-standing questions on the pre-metazoan function of developmental genes and to inform the mechanistic basis of the transition from cell shape to organism shape in both development and evolution.

Keywords: morphogenesis,mechanobiology,pattern formation,evo devo,evolutionary developmental biology,evolutionary cell biology
Arthur will be the first EU-based comprehensive solution for text-based AI applications. It gathers unstructured data from 40+ file formats and transforms it into AI-ready JSON files. (Arthur)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 18.0
Total project cost (EUR): 672000.0
EU funding (EUR): 672000.0
Participants: 1
Project status: SIGNED

ObjectiObjective of the proposal European organizations need a specialized company to securely extract their data safely and on EU servers, in compliance with EU's security standards. Arthur will be the preferred service for all European organizations looking to develop their own AI solutions. In fact, it handles the first and most crucial step in all text-based AI applications: collecting unstructured data from any source and converting it into AI-compatible JSON files. How it will be achieved Our pipeline (currently at TRL5) already manages everything from the initial document intake to the final extraction and processing of content. By leveraging our company's 10-year experience in the field and with the help of this EIC grant, we will bring it to TRL8. We need to complete the technology implementation (including encryption, anonymization, data retention policies, multi-tenancy, security) testing, and develop a go-to-market strategy. Relevance to the work programme Through Arthur, we will assist EU organizations in extracting and utilizing their data securely and be the foundation layer of their AI-transition. This fits with the IV.2.1 challenge, as it provides critical support to new generative AI solutions. It focuses on improving the efficient use of current models while addressing challenges such as hallucination or limited model knowledge. - By providing organizations with clean data ready for AI, we will offer a tool that provides crucial support to developers of generative AI solutions. - By assisting organizations in extracting and utilizing their own data for their AI applications, we aid them in developing AI systems that are naturally less susceptible to errors, easy to verify, and more transparent (which is one of the primary objectives in the EU’s AI Act). - Arthur will be the first (and so far only) data-extraction service based in the EU. This will help decrease dependence on foreign technologies and services, while protecting European data.

Keywords: etl,data extraction,retrieval augmented generation,rag,generative ai,human centric ai
LPool - Rack-scale servers to Revolutionize AI Datacenters for Fast, Sustainable, Cost-efficient Computing (Lpool)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open 2025 (HORIZON-EIC-2025-ACCELERATOR-02, 2025)
Start date: 2025-12-01
End date: 2027-11-30
Duration (months): 24.0
Total project cost (EUR): 3571427.14
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Over the past decade, the on-device performance of CPUs, GPUs, and AI accelerators has improved 100x faster than off-device data movement. This increasingly causes chips to wait for data, lengthening the time to run a job. This data bottleneck thus leads to massive inefficiencies, raising the cost, energy consumption, and carbon footprint to run AI jobs by 57% for datacenter providers and their end-users. ExpectedIT's solution consists of two new proprietary chips: the Large Pool CPU (LP-CPU) chip, its matching Pool chip, and accompanying novel server packaging technology. ExpectedIT will license the intellectual property (IP) for these innovations to chip and datacenter server vendors, enabling the best use of each device's precious off-device data movement. By removing the bottleneck, ExpectedIT's new solution allows AI or other data-intensive applications to run up to 10x faster. By completing the jobs in less time and using fewer hardware resources, LPool will offer datacenters and their end-users up to 2x reduction in costs, energy consumption, and carbon emissions to run a specific job. Our LPool technology will thus significantly impact AI's scalable and sustainable growth for diverse sectors like healthcare diagnostic AI, greentech, enterprise generative AI, and much more. We have validated our technology through over 100K simulation runs of the Verilog code. Based on these promising results, we have attracted the interest of one of the world's leading chip vendors with whom we are in active discussions for them to license the IP for our technology. This project will allow ExpectedIT to complete the engineering of the full chip logic for the Pool chip, the LP-CPU, and server packaging. It will also enable us to double our team size to 30 to carry out these activities, including business developers, to accelerate our go-to-market. Our ambition is to reach 5 licensees and generate over €110 million in royalty revenues by 2031.

Keywords: large pool computer,data centre,computer hardware,high performance computing,server packaging
Upgrading Product Sustainability by VOC and Odour Capture in Automotives and Packaging​ (UPSCAP)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 1971125.0
EU funding (EUR): 1971125.0
Participants: 1
Project status: SIGNED

Currently, of the hundreds of millions of tonnes of plastics produced, only 9% of plastics waste is recycled. The rest is incinerated, mismanaged, or landfilled. With worsening climate change and plastic pollution, there is an urgent need to increase the use of recycled materials. Post-consumer recycled (PCR) materials are an ideal option. However, unpleasant odours and toxic volatile organic compounds (VOCs) reduce quality and increases price for PCR materials due to limited supply of quality raw materials, limiting their applications. AqFresh, an innovative solution to this market need, effectively removes odours and VOCs from PCR materials, enhancing their quality and availability for wider applications. Traditional methods for odour removal are often ineffective and energy-intensive. AqFresh offers superior performance, broad-spectrum capacity, ease of application, and robust intellectual property protection. The technology is available from Aqdot’s mid-scale plant in Spain with annual capacity of up to 500 tonnes and is looking to be scaled further. The global recycled plastics market is projected to grow to £76.6Bn by 2030 at an annual rate of 9.5%, driven by regulatory changes aimed at reducing plastic pollution and promoting a circular economy. The European Commission mandates higher recycled plastic content in vehicles and packaging by 2030. Aqdot will disrupt the recycled plastics market, aligning AqFresh’s development with these regulations to provide a cost-effective, odour-reducing solution for achieving sustainability goals. AqFresh is currently at technology readiness level (TRL) 5 and manufacturing readiness level (MRL) 7. This project will scale AqFresh by optimising specifications, validating prototypes through customer trials, streamlining the manufacturing process to reduce costs and ensuring regulatory compliance. The goal is to achieve TRL9 and MRL9, delivering a cost-effective, high-quality product ready for mass market adoption.

Keywords: sustainability,recycled plastics,chemical innovation
Marine Solar Initiative for Nearshore Locations (MARISOL)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2252442.5
EU funding (EUR): 2252442.5
Participants: 1
Project status: SIGNED

The world seeks cleaner energy solutions, renewable energies, particularly solar and wind, are poised to play a crucial role in decarbonizing energy generation. However, the deployment of these technologies often faces a significant challenge - the scarcity of available land space, especially in densely populated regions like Europe. HelioRec presents an innovative and scalable solution to address this issue by harnessing solar energy from seas through nearshore floating solar power plants (FSPP). HelioRec's nearshore FSPP is not only groundbreaking but also economically viable and fast to deploy. The company seeks funding to test, commercialise, and mass-produce these patented floating systems within the European Union (EU), covering both the European market and later expanding into international markets. The company has already developed 3 versions of floaters designed for nearshore locations over the past 4 years and is currently working on its 4th generation, which promises to be highly competitive in terms of pricing and robustness. HelioRec boasts a team of 9 highly experienced individuals, including 5 PhD holders. HelioRec is on a mission to make a significant impact. By 2028, the company anticipates saving: - 10,463 tons of CO2 emissions/year; - €3.4M/year for the customers; - 200,000 m2 of land space. HelioRec has demonstrated early market traction with a track record of generating €300k revenue up to now and a growing customer base, including 11 LOIs and a forthcoming 5-year contract with TotalEnergies (France). As a young, innovative company, HelioRec was able to close a pre-seed investment round of €500k in 2022 and €1.2M in its seed-round in 2023. HelioRec invites you to be part of this groundbreaking journey. With the propulsion of our cutting-edge nearshore floating solar technology, we are redefining the landscape of solar energy generation. Join us now, as we embark on a mission to revolutionise the way we harness renewable energy.

Keywords: floatingsolar,marine,renewableenergy