Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Fully Electrically Controlled Ultra-fast Chiral Light Handedness Switching in Organic Light-Emitting Devices (FastE-Chiral)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-03-01
End date: 2030-02-28
Duration (months): 60.0
Total project cost (EUR): 2159604.0
EU funding (EUR): 2159604.0
Participants: 1
Project status: SIGNED

Chiral light, with a rotating electromagnetic field, is revolutionizing optoelectronics, quantum optics, and spintronics. This unique light delivers either 'left' or 'right' optical information based on its polarization, similar to how alternating electrical signals transfer sound and images. Despite centuries since the discovery of chiral light, achieving electrical modulation of its handedness in light-emitting devices remains a significant challenge. Traditional methods of switching chiral emission handedness, e.g., inverting material stereochemistry or mechanically rotating optical filters, encounter practical limitations: complicated fabrication and slow switching speeds. However, electrical modulation of light handedness simplifies manufacturing processes, and enable in-situ controllability. This allows for not only the switching of handedness but also capability to do so at high frequencies. My approach departs from prior research. Instead of focusing on emitters, I will investigate the largely overlooked molecular environment of these emitters—the host materials. These materials account for ~90% of host-emitter blends and significantly influence the transport properties of organic light-emitting devices, but their role has been surprisingly neglected in previous research. My objective is to create a chiral environment for emitters using chiral host materials, thereby manipulating electron behavior. Such transport behavior will ‘polarize’ the entire recombination processes, making the chiral emission handedness dependent on current flows. Integrating these materials into a new chiral organic light-emitting transistor, the goal is to achieve ultra-fast handedness switching of highly polarized chiral emission within a single device. Despite notable challenges, creating such light sources offers direct chiral light generation and rapid control over its handedness, potentially revolutionizing future optical communication, imaging, and display technologies.

Keywords: chiral materials,organic semiconductor,circularly polarized luminescence,organic light emitting devices
Environmental Effect on Health Care and Wellbeing and Active Interventions (ENACT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Living and working in a health promoting environment
Action type: Research and Innovation actions
Countries involved: Belgium,Spain,Estonia,Greece,Italy,Bulgaria,Finland,Ireland,Romania,Netherlands
Call: The role of environmental pollution in non-communicable diseases: air, noise and light and hazardous waste pollution (HORIZON-HLTH-2024-ENVHLTH-02-two-stage, 2024)
Start date: 2025-01-01
End date: 2028-06-30
Duration (months): 42.0
Total project cost (EUR): 8764491.2
EU funding (EUR): 7997612.77
Participants: 21
Project status: SIGNED

Non-communicable diseases (NCDs) account for 80% of the disease burden as well as for the majority of premature deaths in the EU; diminishing the citizens’ quality of life, life expectancy and increasing the financial burden (from those affected to the health system). During the last 3 decade environmental stressors have been addressed through numerous studies, which have raised concerns about the detrimental effects of the environment on human health. Most evaluated environmental stressors are air temperature, particulate and gaseous air pollutants, urban noise, food pollutants and radiation. By end of 2022, air pollution was reported to be responsible of an excess mortality of 311.000 people per year in the UE-27 , driving not only premature deaths but also an increased risk of vascular diseases such as ischemic heart disease, stroke, and other non-communicable non-vascular diseases like chronic respiratory diseases or depression. Some newly considered stressors such as electromagnetic field, and light exposure are also susceptible to affect human health (e.g ocular and dermatological NCD diseases). ENACT aims at building a pathway to generate clinical, technological and economic short & long-term impact targeting local and regional stakeholders and create impact by: Developing a state-of-the-art environmental risk score and analyser driven framework and platform to predict, monitor and prevent the exposomic risk of acute and chronic health conditions of chronic vascular and non-vascular NCDs. This new exposomic risk score and analyser will support (a) patients, (b) health professionals/hospitals, and (c) policy makers; aiming at reducing the human and financial burden of NCD, considering potential individual vulnerability factors, and reinforcing both a clinical and a policy implementation that enables prevention and disease management for higher quality of life.

Keywords: exposomic,risk analysis,ai,prevention
Regulation of epithelial-cells renewal by basement membrane protein composition and stiffness during gut homeostasis (ReGutBM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

The intestinal epithelium forms a tight barrier against pathogens and toxins while simultaneously absorbing ions and nutrients. It is the fastest self-renewing tissue in the body, as over 3-5 days, a complete turnover of epithelial cells is achieved. Homeostasis is maintained by tight coordination between epithelial cell proliferation, differentiation, migration, and extrusion. Epithelial cells adhere and migrate on the basement membrane, a unique, sheet-like extracellular matrix that separates epithelial cells from the underlying mesenchyme. Composed primarily of laminins and type-IV collagen, the basement membrane provides structural support, promotes cell adhesion and polarity, and serves as a mechanical and biochemical signaling hub. Although great advances have been made in identifying morphogenetic regulators of epithelial-cell renewal, spatial regulators that limit proliferating cells to the crypt or guide cell migration towards the villus tip are still missing. Interestingly, basement membrane protein composition varies across the crypt-villus axis, which could also affect its stiffness. However, whether these variations play a role in regulating epithelial cell renewal has not been addressed. The overarching hypothesis of ReGutBM is that basement membrane protein composition and / or stiffness define specific zones that promote cell proliferation or cell death, and provide cues for directional migration of epithelial cells in gut homeostasis. Using ex-vivo tissue cultures and in-vivo mouse models, I will characterize the basement membrane protein composition and stiffness. Using 2D intestinal organoid cultures, I will decouple the regulatory impact of tissue stiffness and protein identity on epithelial cell renewal, and identify the molecular mechanism which facilitates BM-epithelia crosstalk during gut homeostasis.

Keywords: gut homeostasis basement membrane cell matrix interactions cell migration organoid
Scaling up the FINAPP Cosmic Ray Neutron Sensing probe. (finapp cosmic ray neutron sensing)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator Challenge: Novel technologies for resilient agriculture (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 2969246.25
EU funding (EUR): 2078472.38
Participants: 1
Project status: SIGNED

The water present in the soil, in the biomass and in the snow represents extremely sensitive data for various sectors. Monitoring soil moisture is crucial in agriculture to irrigate efficiently, save water and costs, and obtain a healthier and more abundant harvest. The snow water equivalent (water content in the snow pack) is a crucial parameter for water availability forecasting for spring/summer. Finapp’s Cosmic Ray Neutron Sensing (CRNS) probes are novel, next-generation, water-content estimators with a broad range of applications. They detect the neutrons generated from the interaction of cosmic rays with the Earth atmosphere and water surfaces, and from those measurements, they estimate the water content. All probes are connected to an AI-based, IoT cloud that provides the data in real-time via a user interface, and estimates specific factors for each of the applications in the different industries (e.g., plants/crops health, fire risk).

Keywords: iot,ai,water management
SERS-based Technology for EarLy Liquid biopsy Analysis and Recognition (STELLAR)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-07-01
End date: 2026-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

STELLAR introduces a groundbreaking approach to early cancer detection, leveraging surface-enhanced Raman spectroscopy (SERS) and artificial intelligence (AI) to analyse microRNAs (miRNAs) in liquid biopsies. This innovative technology aims to revolutionize cancer screening by offering a non-invasive, cost-effective, and highly accurate method for identifying cancer-specific miRNA biomarkers. STELLAR's core innovation lies in its ability to detect and discriminate between normal and mutated miRNAs with exceptional accuracy, even at the level of single nucleotide polymorphisms, without the need for expensive and complex sequencing technologies. The project encompasses the development of a comprehensive system, including a novel miRNA isolation and enrichment method, a SERS-based detection platform utilizing silver nanoparticle-enhanced substrates, and an AI algorithm for data analysis. This integrated approach promises to overcome current limitations in miRNA-based cancer diagnostics, such as high costs, lengthy processing times, and the need for specialized equipment and personnel. STELLAR aims to progress from TRL 2/3 to TRL 4/5, validating the technology with clinical samples and establishing a clear path toward commercialization. The project's multifaceted strategy includes rigorous technical development, IP protection, regulatory planning, and market analysis. The project's success could significantly impact early cancer detection rates, improving patient outcomes and reducing healthcare costs. STELLAR's approach to combining SERS technology with AI-driven analysis opens new avenues for personalized medicine and could set new standards for AI-integrated medical devices. As the project progresses, it will explore various commercialization pathways, including the potential creation of a spin-out company or licensing agreements, with the goal of bringing this transformative technology to market and making a substantial impact on global health.

Keywords: liquid biopsy,mirna,early cancer detection,surface enhanced raman spectroscopy,artificial intelligence,personalized medicine
Detectable leptogenesis and explaining dark matter non-detection using non-standard cosmology and multi-component dark matter models (DLEAD)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 209483.28
EU funding (EUR): 209483.28
Participants: 1
Project status: SIGNED

The initial hint of DM came from F. Zwicky in 1933 while studying the Coma cluster. Since then, extensive evidence has confirmed DM's existence and its relic density has been precisely measured. However, the particle nature of DM remains unknown. Despite numerous experiments -direct, indirect, and collider searches, no signal has been detected. Recent limits from LUX-ZEPLIN 2024 have tightly constrained the DM parameter space, nearing the neutrino floor. This proposal addresses DM non-detection by opening up new parameter spaces that have not been fully explored. We will investigate three scenarios beyond the standard WIMP and FIMP models which have either faced significant constraints or are challenging to detect. First, we will explore baryon asymmetry through new diagrams contributing to lepton asymmetry and FIMP DM production from WIMPs in a non-standard cosmology. Additionally, lepton flavour violation, neutrino mass, and gauge coupling unification will be investigated. We will consider a super-WIMP-like mechanism for FIMP-type DM, with potential long-lived particle signals detectable at FASER/MATHUSLA and contributions to relativistic degrees of freedom observable at CMB-S4. Second, we will analyse inflationary models resulting in a low reheat temperature. By setting the mother particle mass higher than the reheat temperature, we can achieve FIMP DM production at stronger couplings due to the Boltzmann-suppressed number density, potentially explaining the lack of DM detection so far. Third, we will explore a multi-component DM model where one component annihilates into another which then annihilates into Standard Model particles. By adjusting the second component’s fraction, we can evade current bounds and offer future detection prospects. The first, inert component helps account for the total DM density. The proposal is timely in the context of DM non-detection and suggesting new detection avenues across various methods.

Keywords: dark matter,leptogenesis,freeze in,freeze out,neutrino mass
Protecting and stimulating plurilingual identities in learners in Europe via inclusive policies and classroom practices (Pluridentities)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Belgium,Netherlands,Spain,Aruba,Sweden
Call: Strategies to strengthen the European linguistic capital in a globalised world (HORIZON-CL2-2024-HERITAGE-01, 2024)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 2695006.25
EU funding (EUR): 2695006.25
Participants: 6
Project status: SIGNED

The linguistic capital of Europe forms an important part of the EU-identity, yet there are a number of challenges that threaten this capital. In this project, the focus will be on problems that affect and can be effected by education only. The rise of English as lingua franca caused other languages to be pushed to the sidelines, leading to situations where pupils are less or even not motivated to learn other languages besides English even if it concerns an official national language of their country. Although multilingual programs like Content and Language Integrated Learning can affect these attitudes, the large majority of these kind of programs also use English as target language, which does not increase the proficiency in other (foreign) languages. A second threat to the linguistic capital has to do with the protection of heritage languages, where we see that the linguistic capital of EU-citizens more and more includes non-EU languages. In schools, homelanguages are often rejected and usage of them is sometimes even punished, leading pupils who are ashamed of their linguistic capital and have a lower sense of belonging. The increasing popularity of new technologies like ChatGPT and machine translation also threatens to acquisition of languages, as pupils do not feel the need to learn languages any more. At the same time, these new technologies offer many opportunities for teachers in their classrooms. All these treats can be managed via good evidence-based policies at different governance levels and by ensuring teachers receive sufficient training and inspiration on how to accept and stimulate the linguistic capital of pupils. This will be done in this project via intense collaboration with stakeholders at different levels, to ensure that sustainable guidelines, policies and practices can be implemented.

Keywords: education language policy multilingual education technology identities
EffIcient Fullerene-Free organic solar cELls (EIFFEL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Belgium,Netherlands,Spain,France,Denmark,Cyprus,United Kingdom
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2024-02-01
End date: 2028-01-31
Duration (months): 48.0
Total project cost (EUR): 2807655.47
EU funding (EUR): 2641097.87
Participants: 23
Project status: SIGNED

The accelerated urgency of transitioning away from fossil fuels is driven by climate change, but also by the European energy crisis in the wake of the COVID-19 pandemic. It reinforces the demand for competitive solar energy conversion technologies. Organic photovoltaics (OPV), based on non-toxic abundant raw materials offer an inexpensive technology with vast opportunities for largescale roll-to-roll production that is scalable to the multi-terawatt level. After a decade of R&D, several European companies are entering the market with OPV products. However, new materials, so-called non-fullerene acceptors (NFAs), have recently been discovered and have yielded higher power conversion efficiencies. This development occurred mainly in China, so that Europe is at risk of losing its leading industrial position to the Asia. To reverse this alarming trend, Europe needs to increase its strategic investments into OPV research. Two key directions of particular importance are: tailored novel NFA materials and NFA-based solar cells with long operational lifetime. Our scientific goal within EIFFEL – EffIcient Fullerene-Free organic solar cELs – is to recruit, train and supervise 10 talented Early Stage Researchers (ESRs) to design and synthesise novel NFAs suitable for both solution and vacuum processing, for the next generation of efficient and stable OPV. In EIFFEL, the unprecedented combination of targeted simulations, organic synthesis, device characterisation and engineering based on industrial needs paves the way to products that overcome OPV’s present-day limitations. EIFFEL’s training programme is uniquely designed to provide the ESRs with multidisciplinary training interlinking chemistry, materials science, physics, computer science, and transferable skills. EIFFEL’s ambition is to form a new generation of creative, entrepreneurial and innovative young researchers with the organisational abilities needed to succeed in interdisciplinary high-tech sectors.

Keywords: organic photovoltaics,non fullerene acceptors,materials by design,operational stability,efficiency limiting processes,photophysics,microstructure characterization,quantum chemistry
Palladium anchored Halide Perovskites for Solar-driven Diphenyl Carbonate Synthesis (SolarCar)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-06-01
End date: 2025-05-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: CLOSED

Global CO2 emission dominated by burning fossil fuels is resulting in serious societal and environmental issues. To reduce CO2 emission, it is ultimately needed to move away from the reliance on fossil fuels and develop new processes and technologies for CO2 capture and transformation to value-added chemical and products. This project aims to develop and validate an innovative concept for solar energy-driven diphenyl carbonate— essential monomer for polycarbonate—synthesis by coupling CO2 reduction and phenol oxidation half reactions over palladium single atom supported bismuth-based porous halide perovskite photocatalyst. The proposal consists of key scientific and technological targets and objectives; i) modulation of band structure and creation of defects sites on morphology-controlled halide perovskites for anchoring of palladium single atom sites, which will result in a new class of hybrid materials, ii) demonstration of the proof of concept of CO2 reduction and phenol oxidation half-reactions, and the combination of their intermediates to form diphenyl carbonate over hybrid photocatalyst, which is an untouched research territory and has great scientific and technological potentials, iii) exploration and gaining insights about reaction mechanism by using state-of-the-art spectroscopic methods and theoretical predictions. This high-risk/high-gain project is expected to have far-reaching scientific, economic, technological, and societal impacts.

Keywords: solar driven photocatalyst single metal atom halide perovskite,diphenyl carbonate production coupling of photo redox radical intermediates