Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Demand Response - Residential Innovation for a Sustainable Energy system (DR-RISE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Efficient, sustainable and inclusive energy use
Action type: Innovation actions
Countries involved: Spain,Greece,Italy,Germany,Ireland,Bulgaria,Belgium,France,Switzerland
Call: Demand response in energy-efficient residential buildings (HORIZON-CL5-2022-D4-01, 2022)
Start date: 2023-06-01
End date: 2027-05-31
Duration (months): 48.0
Total project cost (EUR): 7045815.0
EU funding (EUR): 5894433.75
Participants: 14
Project status: SIGNED

Due to the current energy crisis, the EU is reaching a critical point in the energy transition with the Clean Energy Package. Residential demand response (DR) is a promising framework whose potential is completely untapped nowadays. DR-RISE's main objective is to demonstrate the benefits of DR in the residential sector, not only for the end-consumers but for the overall energy system and the actors involved. We will offer a holistic set of tools and services with a twofold objective: increase energy efficiency via optimal management and demonstrate the benefits (not only economic) of DR. The platform will be demonstrated in three different EU countries, focusing on gathering the most diverse environments (e.g., pre-existing energy communities, smart villages, urban blocks of flats, low-income households, etc.). Our approach is completely aligned with the EU's vision to place the citizens at the heart of the solution and empower them so that they can make self-aware decisions. Furthermore, we have developed a methodology around a strong social component that includes a significant co-design process of the tools with the end-consumers, considering vulnerable groups to provide a completely inclusive solution. A first iteration in the pilots will be deployed to assess the DR benefits, including the minimum required devices to do so. Then, building on the previous results, we will iterate a second time by including new hardware and DR approaches to compare the outcomes with the previous baseline. This two-phased methodology will allow us to take corrective measures if needed and assess the potential benefits of multiple sensors and control devices. The platform will therefore reach TRL7/8 by project completion. Furthermore, our plan for dissemination and exploitation, including communication activities, contemplates building the energy helix to reach more than 150 relevant organisations and potentiate clustering activities with initiatives such as BRIDGE and Built4People

Keywords: demand response,prosumer,energy market,energy transition,active consumer
pRisoners, escapers, and their afterlives: yUgoslav pows iN itAly in World wAr II and beYond (RUNAWAY)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Switzerland
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-01
End date: 2028-12-31
Duration (months): 36.0
Total project cost (EUR): 412700.52
EU funding (EUR): 412700.52
Participants: 3
Project status: SIGNED

The case of Yugoslav prisoners of war (POWs), held in Italy from the invasion of Yugoslavia in April 1941 until their mass escape following the Italian capitulation in September 1943, is still overlooked in the literature on WWII. However, it reveals crucial dynamics of the history of 20th century Europe: the fascist imprisonment system; the diverse (civil and international) forms of resistance; and the interplay between wartime memories and the Cold War geopolitical divisions arising after 1945. RUNAWAY aims to: 1) map the Yugoslav POWs’ trajectories during the war (camps, escape routes to Switzerland) and in the aftermath (repatriation or migration); 2) illustrate how these trajectories were shaped by encounters with Italian civilian helpers and partisans; 3) in-depth analyse how their overall experiences as prisoners and fugitives were transformative to their own identities, decisions and memories over time. RUNAWAY is based on a mixed interdisciplinary methodology which, through a wide range of archival searches and oral interviews in Switzerland, Italy, Serbia and Slovenia, integrates tools of military, social and political history combining paradigms of micro- and macro-history. It ambitiously bridges academic research with digital and public history through dissemination tools (maps, databases, hiking trails’ plan) which will contribute to raise public awareness of the Nazi-fascist invasion of Yugoslavia and its consequences, aligning with the commitment to preserve the legacy of European history as a pillar of EU values. The training and research activity conducted within the project will significantly expand the research’s competencies in social, political, digital and public history.

Keywords: yugoslavia,prisoners of war,italy,world war ii,civil resistance,international resistance
Diagnostics for cancer and cardiovascular diseases based on diet-derived sugars (SugarBiomarker)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Israel
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-02-01
End date: 2025-07-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Diet can dramatically affect health, and different dietary habits have been associated with various human diseases such as cancer, cardiovascular diseases (CVD), type II diabetes, obesity, and hypertension. In particular, high consumption of red meat has been frequently suggested as a risk factor for human cancers and CVD. We aim to develop biomarkers for cancer and CVD based on signatures of antibodies against glycans. We developed unique nano-printed arrays with various glycans. These will be used for high-throughput serum screening of a large cohort of individuals with validated diet and disease conditions, followed by deep-learning analysis. Unique signatures of antibodies could potentially identify such diseases at an early stage, to allow personalized dietary recommendations or a better therapeutic window. Thereby, such novel sugar-based disease diagnostics could dramatically improve prognosis of cancer and CVD.
Letting up senescence and inflammaging through T cells (Let T Be)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and I mmunotherapy
Panel description: The immune system , related disorders  and their mechanisms , biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases , innovative imm unological tools and approaches , including  therapies
Countries involved: Spain
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-03-01
End date: 2028-02-29
Duration (months): 60.0
Total project cost (EUR): 1999944.0
EU funding (EUR): 1999944.0
Participants: 1
Project status: SIGNED

With the increase in human life expectancy, there is an urgent need to understand the common molecular pathways by which aging results in a progressively higher susceptibility to chronic morbidity, disability, and frailty. In the last years, immunometabolism has emerged as a new field to boost immune responses for cancer immunotherapies as well as to dampen autoimmune diseases. A recent discovery from my lab has revealed the critical role of T cell metabolism in accelerating the onset of age-associated diseases and multimorbidity. This finding has opened a new path to investigate the diverse T cell intrinsic and external stimuli that instruct T cell differentiation towards a dysfunctional state during aging, with the final goal of designing effective strategies to promote healthy aging. LetTBe will address the hypothesis that the time-dependent deterioration of T lymphocytes contributes not only to immunosenescence but also to the general aging process. The LetTBe project proposes to use multidisciplinary approaches to target age-associated T cells for preventing inflammaging, senescence and age-associated multimorbidity. Our central goals are: 1) To define age-associated T cells heterogeneity with special focus in their cellular origin, clonality, metabolic vulnerabilities and transcriptomic signatures; 2) To decode the environmental signals that are imprinted on age-associated T cells and contribute to their development; 3) To identify new strategies to targeting age-associated T cells for slowing down immunosenescence, and for boosting resilience to inflammaging, systemic senescence and age-related multimorbidity. In sum, LetTBe puts forward an ambitious but feasible program with the wide purpose of understanding the specific molecular mechanisms and metabolic requirements of age-associated T cells, with the final goal to guide new strategies to improve healthy aging.

Keywords: immunosenescence,immunometabolism,aging,age related diseases
Go to market for the first European ITAR free modular micro control moment gyroscope actuator enabling 10x more in-orbit agility to small satellites ranging from 50kg to 300kg (SATAGILITY-GO2MARKET)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Belgium
Call: EIC Accelerator Open 2021 (HORIZON-EIC-2021-ACCELERATOROPEN-01, 2021)
Start date: 2022-04-01
End date: 2023-10-31
Duration (months): 19.0
Total project cost (EUR): 2419875.0
EU funding (EUR): 1510469.0
Participants: 1
Project status: CLOSED

Every day, satellites help Europe to respond better to new global and societal challenges: climate change, disaster management, security threats, migration, farming, transport, or energy. To accomplish their mission, satellites need actuators to manoeuvre (i.e. change their orientation) and point towards the necessary targets on Earth (e.g. to collect imagery or simply to communicate). Our company, VEOWARE SPACE has developed an innovative next-gen space actuator technology enabling satellites to manoeuvre 10 times faster to boost their effectiveness. Our solution is a Control Moment Gyroscope, the microCMG. VEOWARE’s technology has been fully tested and qualified on ground but to ensure product viability customer require an in-orbit demonstration. This project aims at bringing VEOWARE to market with a first flight in orbit and the scaling up of the sales team to prepare serving customer by 2023.
Transcranial photobiomodulation for motion sickness mitigation (PhotoMod)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-01-01
End date: 2026-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Cyber- and motion sickness are debilitating for many people, limiting both travel opportunities, and the use of new technologies such as virtual and augmented reality. These forms of sickness are due to nauseogenic sensory mismatch (NSM). Cybersickness affects up to 50% of people use who AR and VR headsets. Motion sickness affects 30% of travellers in all forms of transport, with even more getting sick if they use AR or VR as a passenger. To mitigate the effects of NSM, the PhotoMod project will demonstrate the efficacy of a novel transcranial photobiomodulation (tPBM) technique using near-infrared light. This is delivered by LEDs on the scalp shining invisible light into the brain, focused on the human vestibular network (HVN) to create neural entrainment. Our novel method extends work on the ERC ViAjeRo project which used transcranial alternating current stimulation to create entrainment in the HVN. We use this to synchronize the phase information of endogenous neural oscillations associated with NSM in the HVN to an external phase stimulus generated by tACS, which mirrors healthy phase information. We have found very significant benefits for NSM with this method. However, tACS has many drawbacks for commercial application. tPBM overcomes all of these as it is: more precise, safer, more comfortable and cheaper. In PhotoMod, we will develop new hardware and software to deliver tPBM in a commercial form, then test it as a mitigation for cybersickness at home and for motion sickness on the road. The final result will be a commercialisable wearable system that can mitigate the effects of cyber and motion sickness across a wide area of applications.
Molecular Spin Interactions in Magnetic Fields of Superconducting Vortices (OPTIMISTIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Finland
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-02-01
End date: 2026-01-31
Duration (months): 24.0
Total project cost (EUR): 215534.4
EU funding (EUR): 215534.4
Participants: 1
Project status: SIGNED

Successful implementation of modern quantum technologies is strongly tied to the efficient realization of quantum bits - qubits that promise to revolutionize our current computational and information processing schemes. However, an outstanding challanges concerns the scalability with an expanding number of qubits, making the execution of complex algorithms problematic. In this respect, molecular spin systems are attractive candidates for a scalable qubit platform. The principal idea of the project is to study the behavior and quantum interactions of molecular spin systems exposed to the magnetic fields at the center of Abrikosov vortices in type-II superconductors (BSCCO, YBCO, NbSe2) using state-of-the-art scanning probe microscopy (SPM). This concept promises access to strongly localized magnetic fields of exceptional strength, offering novel perspectives for molecular qubit research, surface science, and material science. The findings will be further utilized to study magnetic ordering in exotic 2D materials (CrBr3, NiI2) exhibiting noncollinear magnetic ordering. The project's novelty lies both in the methodology and research objectives, which will be achieved via a unique synergy of host group expertise in superconducting substrates and preparation of exotic 2D material systems and researcher's know-how in molecular spin systems and magnetic sensing with functionalized SPM tips (metallocene molecules).

Keywords: high temperature superconductors,stm,afm,tip functionalization,abrikosov vortex,molecular spin,2d materials,magnetic fields,qplus sensor,spin sensing
Spins in two-dimensional materials for tunable magnetic and optoelectronic devices (2D-OPTOSPIN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

In order for modern information technology to continue progressing at a rapid pace we require smaller devices consuming less energy. Magnetic materials provide a promising route for nonvolatile memory devices. However, downscaling them is challenging, and information transfer between devices is hindered by short spin relaxation lengths, making it necessary to convert spin information into charge currents, leading to an increase in power dissipation. The aim of this ERC project is to exploit the properties of two-dimensional (2D) materials to combine highly-efficient magnetic devices with optical communication. Specifically, I propose to seamlessly integrate the unique and highly efficient spin-orbit torques (SOTs) of 2D semimetals with the excellent optical properties of 2D semiconductors. Low-symmetry 2D semimetals present SOT symmetries not seen in conventional devices. These are ideal for the control of perpendicular magnetic anisotropy ferromagnets as used in modern high-density memory devices, with the added advantage of their small size. Due to their reduced dimensionality, 2D semiconductors show strong light-matter interaction, efficient electric control over their optical properties, and low lasing thresholds. When combined, energy-efficient devices can be realized in which nonvolatile magnetic information is optically transported over very large distances. To achieve this goal, I will (1) create externally controlled all-2D SOT devices, (2) realize electric tunability of spins and excitons in 2D semiconductors, (3) demonstrate electrical spin injection in a 2D semiconductor with spin direction controlled using SOTs, and (4) develop externally controlled 2D spin LEDs and spin lasers. This project will pave the way for new generations of information technologies, addressing fundamental aspects along the way. It will enrich the van der Waals spintronics field and provide a new strategy towards energy-efficient data storage and transport at the nanoscale.

Keywords: two dimensional materials,transition metal dichalcogenides,spin orbit torque,optics,spintronics,spin laser,magnetism
NatureCOLOURS: Natural colours delivered by yeast fermentation (NaturalCOLOURS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2023-07-01
End date: 2024-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Colour is an essential characteristic of food, associated with quality, freshness, and taste perception. Natural and synthetic food dyes are added to processed foods to enhance or correct variations and give an expected colour to colourless foods, such as soft drinks or candies. Many synthetic colours cause hyperactivity in children, trigger hypersensitivity reactions, and some are carcinogenic in animal studies. Natural colours do not have such adverse effects and are even health-promoting. While natural colours are in high demand, their natural sources are limited. The goal of NatureCOLOURS project is to create a novel technology for making natural colours by yeast fermentation. The project will bring a pallet of natural colours with health-beneficial effects to the consumer, create new industrial processes and new jobs in Europe, and contribute to the sustainable bioeconomy.
Mechanical characterization of soft tissue in vivo by microstructural imaging and physics-informed neural networks: bridging the gap between biomechanics and clinical practice (MechVivo)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Germany,Austria,Switzerland
Call: ERC SYNERGY GRANTS (ERC-2024-SyG, 2024)
Start date: 2025-09-01
End date: 2031-08-31
Duration (months): 72.0
Total project cost (EUR): 9991449.0
EU funding (EUR): 9991449.0
Participants: 3
Project status: SIGNED

Computational biomechanics is a fast-growing area of science. However, many of its fruits have not yet been translated into clinical practice. The main barrier to the translation of computational biomechanics into clinics is the lack of information about patient-specific mechanical properties of biological tissues. There are some methods for partially assessing these properties, but they have substantial limitations. A major cause of these limitations is the operating principle of current approaches, which rely on the analysis of the response of a tissue to some form of mechanical loading in vivo. To overcome this bottleneck, we propose a paradigm change. We will develop a method to infer mechanical properties of soft biological tissues in vivo based on a fundamentally new operating principle. To this end, we will leverage the synergy of three scientific areas covered by the three principal investigators of this project: (i) magnetic resonance imaging (MRI), (ii) experimental biomechanics, and (iii) physics-informed machine learning. Specifically, we will develop a new type of subvoxel MRI relaxometry to probe tissue microstructure non-invasively and establish a combined experimental and computational framework that will uncover for the first time the mechanistic link between transcriptomics, microstructure, and mechanical properties of soft biological tissues in a detailed manner. By leveraging this information with novel physics-informed machine learning techniques, we will gain the ability to determine the mechanical properties of soft tissues from clinical MRI data and blood samples with unprecedented accuracy and completeness. Our approach will be a crucial steppingstone to translate biomechanical computational models into clinical practice at a large scale. As a proof of concept, we will demonstrate how our new method can support the diagnosis of heart failure with preserved ejection fraction (HFpEF), one of the most common causes of mortality and morbidity.

Keywords: biomechanics,solid mechanics,materials modeling,soft tissue biomechanics