Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Retelling and Repetition: Towards a Literary History of Derivation (DERIVATE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-10-01
End date: 2029-09-30
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Why are contemporary readers so fascinated by retellings of the Iliad or Beowulf? And why have retellings of premodern – ancient and medieval – texts not been taken seriously as a literary practice to date? In DERIVATE, I investigate the striking surge of retellings in contemporary English literature by setting the contemporary texts in a productive dialogue with practices of writing in the Middle Ages. The medieval period offers a perfect point of departure for theorizing retellings as medieval literature was inherently derivative and medieval authors had developed a system for being inventive within a system of derivations. Taking issue with the privileging of that which is new in literary history, I propose a new paradigm for literary history: literary history as a history of derivations. Starting from the premise that retelling is a transhistorical concept, the project sheds new light on the processes of reception that find their expression in the current interest in and relevance of premodern material. The project triangulates (classical) reception studies, medieval literary studies as well as literary theory, especially postmodernist theory, and scrutinizes the practice of retelling premodern (ancient and medieval) texts in contemporary English literature. DERIVATE thus develops a theory of retelling based on the intense engagement and critical comparison with medieval practices of retelling in order to map the wider cultural, historical, and literary contexts and implications of the current trend in retellings of classical and medieval texts (audiences, canon, literary market) as a springboard for developing a literary history of derivations.

Keywords: medieval literature,literary history,postmodernist theory,retellings,contemporary literature,literary theory
Renewable Energy Communities for a justice-Led And Inclusive energy transforMation (RECLAIM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-03-01
End date: 2028-08-31
Duration (months): 30.0
Total project cost (EUR): 261854.1
EU funding (EUR): 261854.1
Participants: 3
Project status: SIGNED

The European Union (EU) is rapidly transforming its energy landscape with the goal of becoming the world's first climate-neutral economy by 2050. Yet, nearly 10% of EU population struggles with basic energy needs. Renewable Energy Communities (RECs) - citizen-led initiatives for local clean energy production and sharing – are seen as a solution for combating energy poverty and meeting the EU’s climate targets. Does this model ensure that “no one is left behind” in the energy transition, as envisioned by the EU Green Deal? RECLAIM addresses this pressing question by evaluating how effectively RECs engage with vulnerable groups, particularly those at risk of energy poverty. It focuses on rural areas, which have long faced ecological, social and economic fragilities and are now central to the expansion of new energy developments. RECLAIM aims to: 1) identify vulnerabilities to energy poverty within emerging RECs; 2) assess how RECs facilitate participation and benefit-sharing among vulnerable groups and 3) implement community practices to enhance inclusion. RECLAIM introduces a transdisciplinary approach that weaves together advanced quantitative methods - such as multi-dimensional spatial analysis, Earth Observation, and vulnerability assessment - with qualitative tools, including surveys and participatory research. This innovative approach is made possible through collaboration with leading climate science institutes at CMCC, a secondment with the GIScience Laboratory at the University of Padova, a non-academic placement with an innovative energy start-up, and ongoing interactions with a diverse network of stakeholders engaged in local RECs. As a result, this project creates a unique training environment, boosting the Researcher’s skills and career. Finally, RECLAIM’s methodology aims to set the groundwork for future research pathways aiming to assess the complex impacts of the energy transition, with an emphasis on inclusivity and social equity.

Keywords: renewable energy communities,energy transition,green deal,rural development,energy poverty,vulnerability mapping,energy justice,spatial analysis,community engagement,participatory research
Genetic basis and adaptive role of risk-taking behavior in a rapidly changing environment (riskADAPT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain,United States
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 2
Project status: SIGNED

The evolutionary relevance of behavioral traits has been largely debated among biologists. Behavioral changes often constitute the first response to changing environmental conditions. This suggests that behavioral variation among individuals within a population potentially represents the raw material for natural selection, ultimately determining the ecological and evolutionary responses to new selective pressures. However, the genetic basis of behavioral traits remains largely unknown. This uncertainty limits our understanding of the role of behavior in shaping the adaptive potential of natural populations. In this project I aim to uncover the molecular underpinnings of risk-taking behavior, a key trait associated with survival in the lizard Anolis sagrei under new predation regimes. First, using restriction site-associated DNA sequencing (RADseq) data, I will characterize the heritability of risk-taking behavior by estimating its additive genetic variance based on multigenerational pedigrees of lizards that have undergone behavioral assessments. I will then search for genomic regions and variants associated with risk-taking behavior by FST outlier scans, selective sweep scans and genome-wide association study (GWAS) with the use of RADseq and whole-genome sequencing (WGS) data. Finally, using whole-genome bisulfite sequencing (WGBS) data, I will explore the impact of DNA methylation on the variation in risk-taking behavior to shed light on the role of epigenetic mechanisms in controlling animal behavior. By characterizing the genetic and epigenetic architecture of risk-taking behavior, riskADAPT will decisively advance our understanding of the role of ecologically-relevant behaviors in the evolutionary adaptation to rapid environmental changes.

Keywords: behavioral evolution,animal personality,rapid environmental change,novel predator,genomics,epigenomics,anolis
European Cultural Heritage Optimised Linked Open Tools (ECHOLOT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Innovation actions
Countries involved: Germany,France,Finland,Belgium,Estonia,Bulgaria,Austria,Czechia,Poland,Netherlands,Slovenia,Spain
Call: A European Collaborative Cloud for Cultural Heritage – Innovative tools for advanced data enrichment (HORIZON-CL2-2024-HERITAGE-ECCCH-01, 2024)
Start date: 2026-01-01
End date: 2028-12-31
Duration (months): 36.0
Total project cost (EUR): 6466281.59
EU funding (EUR): 5992667.36
Participants: 15
Project status: SIGNED

In support of the development and adoption of ECCCH by Cultural Heritage Professionals and Researchers (CHPR), ECHOLOT will make the creation, provision, and reuse of high-quality, semantically rich, and interoperable Cultural Heritage (CH) data accessible to scholars and institutions, significantly lowering the threshold for joining the collaborative cloud. ECHOLOT will address the fundamental issue that, while ever larger amounts of diverse CH data are available through CH institutions (CHIs), the active reuse of this data especially in research and the creative sectors, is hampered by poor quality and lack of interoperability. It will achieve this by seamlessly integrating as a core service in the ECCCH that enables the quality curation and enrichment of CH data, including multimedia, through AI-enhanced workflows combining automated processing and human input. Moreover, it will natively support embedding rights metadata and chain-of-production provenance, thereby preserving the value and integrity of CH datasets. ECHOLOT will serve as an interoperability hub facilitating the exchange of CH data between systems. It will enable CHPRs to publish simultaneously to aggregators, such as Europeana, and open knowledge platforms from the Wikimedia ecosystem, as well as contribute to ECCCH and Common European Data Space for Cultural Heritage (DS4CH). Together, these technical innovations will revolutionise CHPR practices and increase the availability of CH data for reuse and collaboration across institutional and sectoral boundaries. ECHOLOT’s solutions will be validated and tested in five case studies presenting a wide spectrum of CH actors. Maximising the adoption of ECHOLOT and ECCCH will be enabled by social and organisational change measures, including innovative business models co-created with relevant stakeholders. Training resources, interactive workshops and open source software best practices will further support capacity building and long-term sustainability.

Keywords: data enrichment,semantic interoperability,cultural heritage,collaboration,ai innovation,open source software,cultural and creative industries,glam sector,digital humanities,mediawiki software
Revealing enhancer-derived RNA (eRNA) transcriptome: eRNA processing and biogenesis during neuronal stimuli-activated transcription (RNAeBio)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Estonia
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-08-01
End date: 2026-07-31
Duration (months): 24.0
Total project cost (EUR): 151901.76
EU funding (EUR): 151901.76
Participants: 1
Project status: SIGNED

Enhancers are short distal cis-regulatory DNA regions that drive expression of a gene. However, enhancers do not function exclusively as DNA entities. Activated enhancers are transcribed by RNA polymerase II (RNAPII), which produces enhancer-derived RNAs (eRNAs). Production of eRNA creates additional trans-regulatory mechanisms facilitated by DNA-RNA, RNA-RNA, or protein-RNA interactions. Due to eRNAs’ fast degradation rates, and lack of robust and standardized sequencing methods, reports about the molecular nature of eRNA molecules and their processing are conflicting, making mechanisms of gene regulation by eRNA controversial. Even less is known about co- and post-transcriptional processing of eRNA. This project aims to overcome the controversy and fill the knowledge gap by studying a well-defined experimental system, cultured rat cortical neurons, and activation of immediate-early gene (IEG) response, perturbing the core eRNA endonuclease and combining this with eRNA-tailored sequencing, computational and biochemical methods. The developed integrative approach will reveal molecular features of eRNA molecules and their precursors genome-wide, opening the opportunity to study eRNA biogenesis to further understand molecular mechanisms behind the eRNA-mediated gene regulation.

Keywords: rna polymerase ii,enhancer derived rna,eukaryotic transcription,enhancer
Multilayer photonic integration platform for free space optics (BEAMS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1499878.0
EU funding (EUR): 1499878.0
Participants: 1
Project status: SIGNED

The project explores a new class of silicon photonic devices and circuits in a three-dimensional integration technology for the generation, control, and reception of free-space laser beams. This research is motivated by the surging importance of communication, sensing, and imaging applications exploiting optical beams propagating in the free space and their urgent need for compact and flexible devices. Currently available integrated solutions based on planar integration technologies are fundamentally limited by either narrow operational bandwidth and reduced shaping capabilities or small apertures and limited steering ranges. The original idea of the BEAMS project is to overcome these limitations by developing multi-layer antenna arrays, metasurfaces, and photonic control circuits exploiting an approach based on three-dimensional integration. This multi-pronged concept will enable unmatched performance in aperture size, efficiency, bandwidth, control flexibility, and power which cannot be achieved by currently available scientific and technological solutions, enabling the development of integrated photonic devices for long-range and broadband free-space applications. Exploiting these new capabilities, the project will demonstrate in particular innovative photonic devices for optical communications, targeting a kilometer-long communication link in free space with multiple wavelength channels. Through its research program, the BEAMS project will combine the fields of integrated and free-space photonics, opening a plethora of new possibilities with a large impact on science and society.

Keywords: silicon photonics,phased arrays,photonic circuits
Modified Gravity: from Compact Objects to Dark Energy (MGCODE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Czechia
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-02, 2022)
Start date: 2023-01-01
End date: 2024-12-31
Duration (months): 24.0
Total project cost (EUR): 150438.72
EU funding (EUR): 150438.72
Participants: 1
Project status: CLOSED

The origin of the accelerated expansion of the Universe remains elusive. The so-called Dark Energy might be a manifestation of modified gravity at very large scales. While near-future observatories will improve the current bounds on such a possibility, they will not likely be conclusive as to its nature. An opportunity arises from the study of modifications of gravity at shorter scales, specifically around compact objects like black holes and neutron stars, recently made possible through gravitational-wave observations. This project aims to dramatically improve the constraints on cosmological modifications of gravity by means of an interdisciplinary approach involving tools from High Energy Physics, and both astrophysical gravitational-wave and cosmological observations. Modified gravity dynamics at different scales can be described in a model-independent way as Effective Field Theories according to symmetry principles. Strong constraints will come from a combined theoretical and phenomenological study within this framework. Both analytical and numerical tools will be developed and employed to qualitatively and quantitatively compute the expected signatures on gravitational-wave astrophysics, allowing to hold these models against observations. The constraints will then be translated to the cosmological modifications of gravity, drawing novel conclusions as to which theories can consistently explain Dark Energy while satisfying bounds across a large range of scales. Ultimately, this project will foster the collaboration among the High Energy Physics, Cosmology and Gravitational-Wave Astrophysics communities, enabling a much faster and efficient progress in the field of modified gravity in general. This includes a more focused use of the available computational resources for time-consuming resource-intensive tasks. The multifaceted training and support received during the action and the competences acquired are aimed at the career development of the fellow.

Keywords: modified gravity,effective field theory,black holes,gravitational waves
Mucinase-based innovative therapy to enhance cancer treatment (MUC-BITE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2023-01-01
End date: 2024-12-31
Duration (months): 24.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Colorectal carcinoma (CRC) is one of the leading causes of cancer death in women and men. CRC can be broadly subdivided into adenocarcinoma-type and mucinous-type CRC, characterised by an overproduction of mucin proteins which is the primary component of mucus. These mucins form a 'physical barrier' that impedes the accessibility of current CRC therapies to their target receptors, limiting what would otherwise be promising cancer drugs. Dr. Karin Strijbis' group has discovered a compelling mucinase enzyme that can effectively degrade the mucin barrier. Preliminary research performed by Dr. Strijbis' group revealed this mucinase's therapeutic potential to enhance the effectivity of approved anti-CRC drugs (i.e., anti-EGFR antibodies and small molecule inhibitors) by demonstrating the removal of obstructive mucin proteins and a decrease in CRC cell proliferation. In MUC-BITE, we present Nano-MUCase, a novel biological based on the conjugation of this mucinase with a nanobody to selectively target CRC tumours for optimal delivery and removal of the mucin barrier. During this PoC project, we will determine the technical and commercial feasibility Nano-MUCase through the following activities: 1. Validate the capabilities of the Nano-MUCase to target CRC tumours and reduce mucin interference of anti-CRC drugs in organoid samples and in vivo. 2. Define an IP strategy by performing a thorough IP landscape and patentability analysis. 3. Conduct market research to discover potential customers/industrial partners, analyse competitors and identify a feasible roadmap to commercialisation. 4. Formulate a detailed business case to guide the commercialisation of the Nano-MUCase to penetrate the market and deliver a new therapeutic strategy to benefit CRC patients.
Knowledge and manipulation of nature between usefulness and deception in the Arabo-Islamic tradition (9th-15th century) (UseFool)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Italy
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-12-01
End date: 2027-11-30
Duration (months): 60.0
Total project cost (EUR): 1943208.0
EU funding (EUR): 1943208.0
Participants: 1
Project status: SIGNED

The UseFool project studies the knowledge and manipulation of nature applied to entertainment and fraud, as described in the Arabic technical literature dealing with the practice of charlatans and performers along the streets and in the markets. At the core of UseFool’s textual corpus are four Arabic handbooks composed between the 6th/12th and the 9th/15th century, combined with other sources, such as the handbooks for the inspector of the market that focus on artisanal impostures. The project will reconstruct the refined technical notions mastered by marginal social groups, showing how the lightly dismissed ‘popular knowledge’ was actually a form of ‘street science’. The project’s goal is to write a new chapter in the cultural, social, and material history of knowledge looking through the lens of Arabic technical literature. UseFool proposes a new interdisciplinary approach to its sources: this begins from a philological and textual analysis that focuses on their technical contents, expands to the reconstruction of the material dimension of the procedures through hands-on replication, and completes its all-round approach with the re-enactment of the performative and theatrical dimension entailed in the different forms of deception. In this way, UseFool will assess the interaction between the narrative component and actual practice in this textual tradition. The project will also map the sources of this technical literature on deception, in order to reconstruct lines of transmission in a long time span and across different cultures. The project reflects on the roots of the handbooks on entertainment and fraud in the antique and late antique heritage, with the aim of providing a searchable and organized structure to the lore of natural properties. UseFool also expands its horizon to the close relationship between the Arabic and the Latin Mediaeval technical sources, with the aim of deepening our understanding of their transmission in a longue durée perspective.

Keywords: history of knowledge arabo islamic material and artisanal culture arabic technical literature sleight of hand fraud replication and re enactment