Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
C-C Bond Formation Using Top Performing Enzymes (CC-TOP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Germany,Spain,Germany,Germany,Croatia,France,Netherlands,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2021-03-01
End date: 2025-02-28
Duration (months): 48.0
Total project cost (EUR): 3971466.72
EU funding (EUR): 3971466.7199999997
Participants: 13
Project status: SIGNED

Industrial Biotechnology is a Key Enabling Technology under Horizon 2020, expected to boost technological innovation and industrial leadership in the EU. It can improve chemical processes in compliance with the principles of Green Chemistry and effectively address social, environmental and economic needs. Assembling simple fragments to build larger, more complex products is an essential technology at the heart of industrial organic synthesis. With traditional chemical methods, C–C bond formation (“carboligation”) is difficult to control selectively, whereas enzymes can catalyze carboligation with excellent precision. Such addition reactions are ideally suited for industrial applications, being highly atom-efficient and producing no waste material. For unleashing the vast, hidden treasury of enzymatic carboligation, the CC-TOP consortium has identified and will address a number of critical needs, technology gaps, practical challenges and synthetic opportunities presenting a huge potential for innovation. The main goal of the CC-TOP ETN is to deliver tailored training and education to 15 top early-career researchers on cuttingedge carboligation enzyme technology and its translation into efficient Industrial Biotechnology applications, i.e. production of chiral fine chemicals and pharmaceuticals. The training will be implemented within an established network of worldleading European academic institutions and industrial partners, forming strong interdisciplinary relations through cosupervision and inter-sectoral secondments of the ESRs. The network´s aim for efficient translation of breakthrough technology into industrial applications is emphasized through the implementation of an industrial skills module involving all ESRs. CC-TOP combines leading-edge discovery technologies with state-of-the-art protein engineering and structural biology methods to specifically optimize process-validated carboligases for scalable applications in Industrial Biotechnology.

Keywords: enzymatic carboligation,applied biocatalysis,protein engineering,enzyme promiscuity,asymmetric synthesis,aldolase,transketolase
Boosting Cation Exchange in Self-Assembled Supraparticles through Advanced Electron Tomography Techniques (SuprAtom)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-04-01
End date: 2022-03-31
Duration (months): 24.0
Total project cost (EUR): 178320.0
EU funding (EUR): 178320.0
Participants: 1
Project status: CLOSED

Self-assembly of nanoparticles (NPs) offers a versatile platform for the design of novel materials with enhanced collective properties. A promising route to achieving tailored properties with NPs is to bring them together into superstructures called Supraparticles (SPs). The greatest potential for bringing forth diverse new properties comes from multicomponent SPs, in which multiple types of NPs are used in the SPs. I propose to use spherical confinement to first build SPs which I will then treat with cation exchange (CE), a powerful tool for synthesizing NPs with controlled structures. The goal is to establish a robust route to structuring multicomponent SPs in a controlled manner and enable the engineering of new SPs with optimal properties for applications ranging from catalysis to photovoltaics. A complete structural analysis of cation exchanged (CE-ed) SPs in 3D is essential as it will reveal the CE process in SPs. I will develop innovative quantitative 3D electron microscopy (EM) techniques to investigate the dynamics of the structural evolution of CE-ed SPs on the single NP level, providing insights into how to achieve optimal properties. Optimization of sample support and development of fast multimode electron tomography will make this possible by eliminate beam damage. Liquid tomography will allow me to fully understand the 3D structures of CE-ed SPs under realistic conditions. By combining in-situ heating and fast multimode electron tomography, I will decipher the mechanism of heat-induced intra- and inter- particle CE in SPs. My program will enable me to understand the interplay between NP shape, stacking and heating on the resulting SP structures. This program will be the start of a completely new research line in the fields of both colloidal science and 3D characterization. The outcome will boost the possibilities for the design and application of functional materials as well as push the limits of 3D EM techniques.

Keywords: electron tomography,self assembly
A hybrid solar panel that maximises heat capture and electricity generatio (ECOMESH)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-02-01
End date: 2018-05-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

A hybrid solar panel that maximises heat capture and electricity generation. Although solar panel technology is well established, commercial hybrid panels are a recent innovation. A typical PV panel transforms ~20% of incident solar irradiance into electricity – and a thermal panel several times that, into heat. Between the two, there are trade-offs; and the detailed economics – factoring in power prices and other heating costs, etc. – can be very complex. In the end, however, people/businesses need continuous electricity and regular hot water. There is clear need for a solution that delivers both: hence the development and uptake of hybrid panels. The battle is to establish technology (efficiency) leadership – which EndeF has achieved in ECOMESH: the most efficient panel ever built. At the core of the innovation is ECOMESH’s Transparent Insulating Cover (TIC) technology: an advanced heat recovery system which, using an inert gas layer, maximises heat capture. TIC also increases electricity generation by 15%, by cooling the PV cells to their optimum operating temperature.

Keywords: hybrid solar panel,manufacturing,solar energy
Innovation Denmark 2019 (INNODK2019)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Denmark,Denmark,Denmark,Denmark,Denmark,Denmark
Call: EEN H2020 SGA3 (H2020-EEN-SGA3-2018, 2018)
Start date: 2019-01-01
End date: 2019-12-31
Duration (months): 12.0
Total project cost (EUR): 329858.83
EU funding (EUR): 329858.83
Participants: 9
Project status: CLOSED

The objectives of the Innovation Denmark 2019 project are to: • Provide Key Account Management (KAM) services to Danish businesses, which have been awarded grants under the SME Instrument, Future Emerging Technologies or Fast Track to Innovation programmes • Provide Enhancing Innovation Management Capacity (EIMC) services to SMEs in 2019. Companies will be assessed via the Innovation Health Check tools or other approved tools and depending on results, referred on to relevant organisations in the Danish and European innovation eco-system. In total, under both categories 100 service packages will be carried out. The figure is based on an average of 46 KAM packages coming through EIC programmes, and 44 EIMC cases carried out. If a larger number of grants from EIC are given to Danish participants, the packages will be adjusted accordingly. The figures are based on the experience of the Danish consortium since 2014, which has seen a high and increasing number of cases coming through via the SME Instrument, due to the success Danish companies have in the programme.

Keywords: kam and eimc for smei,fet and fti 2019
HYbrid NANOstructured multi-functional interfaces for stable, efficient and eco-friendly photovoltaic devices (HY-NANO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Italy
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-07-01
End date: 2024-06-30
Duration (months): 60.0
Total project cost (EUR): 1499084.0
EU funding (EUR): 1499084.0
Participants: 1
Project status: SIGNED

HY-NANO focuses on one of the current major challenges in Europe: a global transition to a low-carbon society and green economy by 2050. Solar energy can lead a “paradigm shift” in the energy sector with a new low-cost, efficient, and stable technology (3-pillars strategy). Nowadays, low-cost three dimensional (3D) Hybrid Perovskites (HP) solar cells are revolutionizing the photovoltaic scene, with stunning power conversion efficiency beyond 22%. However, poor device stability (due to degradation in contact with water) and dependence on toxic components (lead) substantially hamper their commercialization. HY-NANO aims to realize a new low-cost and efficient hybrid solar technology combining long-term stability with a reduced environmental impact. Design and engineering innovative multi-dimensional hybrid interfaces is the core idea. This will be achieved by: 1. design and characterization of new stable and eco-friendly perovskites structures, with tunable composition and dimensionality ranging from 3D to 2D; 2. exploiting new synergistic functions by combining 3D and 2D perovskites together into novel stable and efficient multi-dimensional interfaces while addressing the interface physics therein; 3. integrating the hybrid interfaces into high efficient and stable device architectures engineered “ad hoc”. In addition, I propose the development of new solar cell encapsulant using metal-organic frameworks (MOFs) functionalized as selective lead receptors to minimize the environmental risks associated with the potential release of lead. My multidisciplinary expertise in advanced material design, cutting-edge photophysical experimental investigations, and solar cell engineering will enable me to successfully target the ambitious goals. HY-NANO is timely and it will generate the new fundamental knowledge that is urgently needed for a scientific and technological breakthrough in materials and devices for near future photovoltaics.

Keywords: hybrid perovskites,photovoltaic materials,solar cell,interface physics,charge dynamics,ultrafast spectroscopy,device engineering
How experience shapes brain specializations (NovelExperiSENSE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Israel
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-10-01
End date: 2024-03-31
Duration (months): 66.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 1745618.75
Participants: 2
Project status: SIGNED

The main goal of my research is to understand the origins of brain specialization and its flexibility across the lifespan. In our modern society Novel Sensory Experiences (NSE) and augmenting technologies are increasingly part of our everyday life (e.g. www.pokemongo.com). How does our brain deal with processing these new experiences? How much of its functional specializations and organization principle (e.g. topography in early sensory and motor brain areas) are already predefined by evolution and are locked after critical periods (i.e. early in life)? Our main hypothesis is that computational tasks, cognitive goals and partially innate network connectivity patterns, rather than sensory input per se, drive the emergence of brain specializations even after the critical periods pass. We base this also on our extensive experience with teaching blind to "see" with their ears using sensory substitution devices (SSDs) and the resulting brain specializations (including putative mechanisms). Here, we will extend, generalize and consolidate this theory by tracking in healthy adults the development of NSE (Novel since never experienced it before during life nor evolution). We suggest here to build 5 novel topographic devices (e.g. we developed recently the IRThermoSense for perceiving heat information and beyond walls thermal images without interfering with regular vision). We will also work with providing novel experiences to congenitally sensory deprived populations (e.g. deaf) to promote sensory restoration. In both cases, we aim to characterize the integration of NSEs in the brain using longitudinal self and supervised learning in virtual and real world environments and cutting-edge biologically inspired computational neuroimaging tools, with special emphasis on topography (similar to how natural senses are represented e.g. body homunculus and retinotopy), task-selective specializations, multisensory and sensorimotor binding, and the emergence of distal attribution.

Keywords: human brain plasticity,brain specializations,multisensory perception,novel sensory experiences,neural recycling theory,neuroimaging,homunculus,topographical organization,sensory restoration
Digital twin for biomass boilers (DT4BIOMASS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Spain
Call: European SME innovation Associate - pilot (H2020-INNOSUP-2019-02, 2019)
Start date: 2019-12-15
End date: 2021-01-14
Duration (months): 13.0
Total project cost (EUR): 75500.0
EU funding (EUR): 75500.0
Participants: 1
Project status: CLOSED

Future biomass boilers face the following challenges in the next years: the improvement of efficiency, the reduction of gaseous pollutant emissions (NOx, CO, HCl and SO2), the reduction of particulate matter emissions, mitigation of problems (fouling, slagging, corrosion) caused by ash deposits formation, flexibility to use different biomass fuels and to adapt to the power demand (start-up time, ramp rates, reducing minimum load). Since the important growth which is expected for this sector in the short/medium term, the enhancement of biomass boilers is becoming more demanded. The manufacturing companies of biomass boilers base their design process in their experience and trial-and-error approaches. Although a reasonable solution can be found with this methodology, it can be far from optimal. Therefore, the digitalization of their design processes is necessary to give a step forward in the biomass boilers design. Simulation models (based on Computational Fluid Dynamics) have been extensively used to improve the design and operation of fossil fuel boilers. However, the incorporation of these techniques to biomass boiler manufacturing companies is insufficient. The higher complexity of the biomass combustion modelling hinders the access to these techniques (higher cost and expertise required) for this industry sector. In this project Nabladot S.L. aims to develop a comprehensive and accurate biomass boiler model which can be adapted easily to simulate any biomass boiler and, in this way, to overcome the barriers to incorporate this technology to biomass boilers manufacturing/operator companies. Nabladot S.L. has available models to simulate any part of a biomass boiler excepting the fixed bed (or grate), which require the application of complex simulation techniques such as the Extended Discrete Element Method. To achieve this, NablaDot, S.L. proposes this project in which is requested the recruitment of an innovation associate (IA) with expertise in XDEM techniques.

Keywords: xdem,simulation of biomass boilers
REconciling sCience, Innovation and Precaution through the Engagement of Stakeholders (RECIPES)

Framework: Horizon 2020 — Science with and for Society
Programme: Take due and proportional precautions in research and innovation activities by anticipating and assessing potential environmental, health and safety impacts
Action type: Research and Innovation actions
Countries involved: Germany,Austria,Germany,Germany,Italy,Norway,Bulgaria,Netherlands,Netherlands,Denmark
Call: Taking stock of the application of the precautionary principle in R&I (H2020-SwafS-2018-1, 2018)
Start date: 2019-01-01
End date: 2022-06-30
Duration (months): 42.0
Total project cost (EUR): 1999831.25
EU funding (EUR): 1999831.25
Participants: 11
Project status: CLOSED

RECIPES seeks to address the highly debated question as to how to protect health and safety of persons and the environment whilst promoting innovation. RECIPES is pioneering because of its a ground-breaking and interdisciplinary endeavour involving the integration of social and legal discipline and based on co-creation with policy-makers and other stakeholders. It aims to reconcile science, innovation and precaution to foster social awareness and responsibility in the EU in research and innovation by developing new empirically sound and theory informed institutional design and tools. It will build effective cooperation between science and society and link scientific excellence with social awareness and responsibility. In order to fully grasp the complexity and the controversies around the precautionary principle, RECIPES will examine the application of the precautionary principle in international treaties, EU level and five countries. It will also carry out eight case-studies, so as to understand and explain the potential differences in the application of the precautionary principle in the different cases, which reflects the particular context of the case and reasoning behind the decision to invoke the precautionary principle. RECIPES will develop new tools for the application of the precautionary principle taking into account the innovation principle. It will involve engagement of stakeholders in all stages of the research. It will moreover develop mechanisms for public involvement in research and innovation. It will develop scenarios for the future application of the precautionary principle and from there, it will co-create a new approach to the precautionary principle and new tolls to help policymakers and other stakeholders to assess risks and uncertainty and allow decisions to be made on a case-by-case basis, responding to the question how to responsibly decide on precaution and innovation.

Keywords: precaution,innovation,science,co creation,interdisciplinary
Efficient Proofs and Computation: A Unified Algebraic Approach (EPRICOT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-07-01
End date: 2026-06-30
Duration (months): 60.0
Total project cost (EUR): 1899675.0
EU funding (EUR): 1899675.0
Participants: 1
Project status: SIGNED

Computational complexity lies at the heart of information and computer science. Its aim is to formally understand the boundary between problems that can be solved efficiently and those that cannot. This has many applications: new algorithms are important to make progress in domains such as machine learning and optimization, and new complexity lower bounds (namely, computational impossibility results) are essential to provably secure cryptography. Beyond practical applications, these questions reveal deep mathematical and natural phenomena. One of the prominent directions to attack the fundamental lower bound questions in complexity comes from the study of resource bounded provability, namely proof complexity. Its aim is to understand which problems possess solutions with short correctness proofs and which do not. Traditionally, proof complexity is concerned with propositional (Boolean) logic, and thus techniques from Boolean function complexity have had a huge impact on the field, driving many of its results and agendas. In this proposal we suggest to employ recent breakthroughs in the field of proof complexity exploiting algebraic approaches to broaden in a systematic way both the scope and techniques of proof complexity, going from weak settings to the very strong ones, up to the major open problems in the field and beyond. In particular, we propose to use algebraic notions and techniques such as structural algebraic circuit complexity, rank lower bounds, noncommutative and PI algebras, among others to significantly broaden the arsenal of lower bound tools as well as develop new models and insights into proofs, computation and their inter-relations. This project has potential for a transformative impact in theoretical computer science and beyond, with applications to unconditional computational lower bounds, which underlie secure cryptography and derandomization of probabilistic algorithms, as well as improved SAT- and constraint-solving heuristics.

Keywords: computational complexity,propositional proof systems,lower bounds,impossibility results,theory of computing,bounded arithmetic,satisfiability,algebraic computing,algebraic circuits,boolean circuits,complexity,proof complexity