Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Hybrid sensor for diabetes detection from exhaled breath using nanoparticles loaded 1D metal oxides (Sensor4Diabetes)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2022-11-01
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

Health and well-being has been one of the kHealth and well-being has been one of the key societal and grand challenges identified in EC Research and Innovation programs. Diabetes is one of the most prevailing chronic health problems across Europe and worldwide. Diabetic patients experience painful blood glucose testing in daily basis which is highly inconvenient. Replacement of blood testing with non-invasive methods would bring a paradigm shift in diabetes management. Human exhaled breath consists of several traces of volatile organic compounds (VOCs) known as “breath marker”. The presence of increased amount of acetone, ethanol and methyl nitrate has been confirmed in diabetic breath by various sophisticated techniques which are not suitable for routine clinical practice or domestic use due to their non-portability, complexity, bulk-size and high costs. Metal oxide sensors have considerable potential in detecting VOCs in exhaled breath. For VOCs analysis in breath requires high sensitivity together with high selectivity. The aim of this project is to develop hybrid sensor for analyzing VOCs in breath from 1D metal oxide nanostructures functionalized with different catalytic nanoparticles. Both impedometric and photonic properties of the sensors will be measured in presence of synthetic healthy and synthetic diabetic breath. The 1D metal oxide nanostructures on sensing platform could provide high surface-to-volume ratio for surface adsorption/desorption of gas molecules together with excellent electronic and optical properties. The addition of catalytic nanoparticles on the surface of 1D nanostructures will enhance the sensitivity and response time towards VOCs by lowering the oxidation energy, increasing the catalytic surface area and catalytic activation of gas molecules. It is expected that adoption of hybrid sensing principle will enhance the selectivity towards individual VOCs which is essential for the development of highly effective diabetic breath analyzer.

Keywords: diabetes detection,breath analysis,gas sensors,metal oxides,one dimensional nanostructures
Drivers of Growth in Bank Lending and Financial Crises (lending)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance and management
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-09-01
End date: 2022-08-31
Duration (months): 60.0
Total project cost (EUR): 2103440.0
EU funding (EUR): 2103440.0
Participants: 1
Project status: CLOSED

Banking crises are thought to be recurrent phenomena that generally come on the heels of strong credit growth. Their damaging real effects have generated a broad agreement among academics and policymakers that financial regulation needs to tighten and to obtain a macroprudential dimension that aims to lessen the negative externalities from the financial to the macro real sector. Among the main ingredients that are often mentioned to have played a role in the explosive growth of credit in the run-up to the latest financial crisis are the financial innovations by financial institutions, in particular loan securitization, the boom in mortgage lending and prices of real estate, the lack of information about prospective borrowers, and the high leverage (and corresponding low capital ratios) of financial institutions. Yet, despite the singling out of these ingredients by policymakers, decisive empirical evidence about their role and relevancy is lacking. However, given the magnitude and complexity of the global banking system and the lack of encompassing micro-level data, it is currently impossible to confidently study the impact of all ingredients jointly. This project therefore analyses pertinent settings where we can empirically identify the correspondence between the aforementioned individual ingredients and the credit granting by financial institutions. The objective of the project is to advance identification and estimation of the impact of each respective factor on loan growth by combining the appropriate methodology with an exceptional set of micro-level datasets. When missing in the literature a theoretical framework will be provided. The project further aims to assess how potential combinations of these ingredients may have interacted in spurring credit growth. While the identification of the impact of each ingredient on credit growth is paramount, the individual setting of the studied datasets and employed methodologies will ensure maximum external validity.
Urban Arena for sustainable and equitable solutions (URBANA)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Coordination and support actions
Countries involved: Austria,Germany,Spain,Germany,Belgium,Hungary,Netherlands,Portugal
Call: Innovative solutions for inclusive and sustainable urban environments (H2020-SC6-TRANSFORMATIONS-2018, 2018)
Start date: 2019-01-01
End date: 2022-03-31
Duration (months): 39.0
Total project cost (EUR): 1499484.96
EU funding (EUR): 1499484.96
Participants: 8
Project status: CLOSED

UrbanA takes up the challenge of synthesizing and brokering the knowledge and experience generated in EU-funded projects, many of which have identified interventions that address grand societal challenges, of which urban inequalities and social exclusion across different contexts. In this way, UrbanA will support city-makers – including researchers, policymakers and practitioners – in transforming European cities into inclusive and sustainable urban and peri-urban environments. UrbanA will do so through a transdisciplinary Urban Arena for Sustainable and Equitable Solutions (established in WP2). By co-creatively mapping urban sustainability interventions (WP3), assessing their potential to improve urban social equity and inclusion (WP4) and identifying potential avenues and agents by which such interventions could be transferred to more widespread governance contexts (WP5), UrbanA will develop actionable and actor specific solutions (WP6), which will be disseminated to key local and European actors (WP7).

Keywords: sustainable urban development,inclusivity and equity,cities,solutions,arena,trandisciplinary research,policy recommendations,co creation,city makers
Quantifying Recycling Fluxes of Earth Surface Materials and Volatiles in Subduction Zones using Melt Inclusions (ReVolusions)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-01-01
End date: 2023-06-30
Duration (months): 66.0
Total project cost (EUR): 1709240.0
EU funding (EUR): 1709240.0
Participants: 1
Project status: SIGNED

Plate tectonics are fundamental to the geochemical cycles that link Earth’s mantle and exosphere and in turn control the atmosphere’s composition and our climate. Currently a major unknown is the exact fate of surface materials at destructive plate-tectonic boundaries (subduction zones). Specifically, what proportions of volatiles, sediments and oceanic crust are transported into the deep mantle, or are returned, i.e. ‘recycled’ to the crust and atmosphere. Global recycling flux estimates, including carbon, are contradictory highlighting the need for a new, more precise approach to their quantification. I propose to better quantify global recycling fluxes by a geochemical study of two types of subduction zones: continental and oceanic zones of which the former has higher volatile fluxes and plays a key role in past and present-day climate change. The proposed work utilises isotope analyses of deeply formed melt inclusions, tiny pockets of melt trapped in minerals, to directly determine what comes back up in subduction zones. Undertaking a multiple isotope study of these inclusions is now possible, owing to my recent success in significantly improving mass spectrometer detector amplifier technology that led to an order of magnitude improvement in precision for isotope analyses of small samples. I will integrate two ground-breaking techniques to identify recycled components and determine volcanic and deep mantle fluxes: 1) coupled Sr-Nd-Pb isotope ratio analysis of individual melt inclusions using the high-gain amplifier method I pioneered; 2) carbon and oxygen isotope analysis of CO2 from melt inclusions using a newly developed crushing technique. The outcomes of ReVolusions will provide crucial understanding of how subduction geodynamics control the distribution of elements between Earth’s major reservoirs (atmosphere, crust and mantle) that affects short and long-term climate changes.

Keywords: subduction recycling,geochemical cycles,subduction zone,melt inclusion
Research of Innovative and Breakthrough Additive Manufactured leading-edge concept (RIB-AM)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Germany,Spain,United Kingdom,United Kingdom
Call: Technological readiness at the operational level for additive manufacturing in primary structure and large size components (H2020-CS2-CFP07-2017-02, 2017)
Start date: 2018-11-01
End date: 2022-10-31
Duration (months): 48.0
Total project cost (EUR): 569958.75
EU funding (EUR): 569956.62
Participants: 4
Project status: SIGNED

RIB-AM project will contribute to the CleanSky 2 objectives with the development of novel manufacturing technologies applied large size components belonging to the primary structure of aircrafts. Within this set of manufacturing techniques stand out the Automatic Fibre Placement (AFP) using thermoplastic resins, the innovative additive manufacturing process with short-fibre reinforce thermoplastic materials or the new methodology for components joining based on inductive welding technology.

Keywords: additive manufacturing,automated fiber placement,induction welding,hybrid joints,cfr peek
Welfare and Hosting buildings in the “Holy Land” between the 4th and the 7th c. AD (HOLYHOST)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2022-09-30
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

Between the 4th and the 7th century AD, many hospices dedicated to the poor, elderly, strangers and travelers were built in the countryside, along roads, around and inside cities. They were commissioned by the Church, rich pious men and women concerned by the redeem of their sins, as well as emperors who saw this as a guarantee of social stability. Welfare is thus an important phenomena of Late Antiquity, abundantly mentioned by ancient literary sources and inscriptions, particularly in the eastern part of the Empire. However, the buildings that provided shelter and care to the needy have not yet received sufficient attention from archaeologists. Except for buildings which were identified by their inventors as hostels dedicated to pilgrims, they are still invisible in the field. The aim of the HOLYHOST research project is to bring this social history’s main topic on the field of archaeology. It will address the welfare issue through the archaeological and architectural survey and study of Ancient welfare and hosting establishments’ remains, in the Holy Land (Palestine and Jordan) and around. This work will contribute to a better understanding of the practices linked to hospitality, welfare, accommodation and care in Antiquity. Moreover, such establishments served as models for medieval and modern Islamic, Jewish and Christian waqf institutions (religious endowment), and welfare continues to be highly relevant nowadays, through issues still at the heart of contemporary challenges debated in Europe: poverty, social exclusion, migrant crisis, principle of reception and hospitality. This interdisciplinary and diachronic research project will thus offer many new research perspectives, in terms of history of architecture, evolution of care practices, social and political regulations.

Keywords: archaeology,architecture,social history,late antiquity,near east,byzantine era,welfare,hospital,hospice,hospitality
The Standard Model Effective Field Theory at One Loop (SMEFTONE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: CLOSED

The Large Hadron Collider and particle physics as a whole is entering a high precision era. A powerful tool for studying new physics in precision experiments where new particles may not be produced directly, but their influence on lower energy physics may be seen indirectly, is that of Effective Field Theories. I propose to use the Background Field Method, a useful formulation in perturbative quantum field theory, to aid in the calculation of one-loop amplitudes in the Standard Model Effective Field Theory. After completing basic calculations allowing for the one-loop program to proceed, I will focus on calculations relevant to Z boson physics first as this is the area most in need of precision calculation and will open the door for important studies of next generation collider design. Then I will finish by calculating the Higgs boson width to one loop order with up to 3 final state particles in the Standard Model Effective Field Theory. This will serve as an update to the tree level Higgs width package currently being produced by myself and my supervisor. A core element of this proposal is the production of another package, tentatively named "SMEFT-ONE," in which I will release the results of all one loop calculations produced as a result of this proposal. The purpose of this package will be the dissemination of the work to the particle phenomenology community as a whole with a focus on the ability to directly use the results in independent studies.

Keywords: effective field theories,the standard model,the standard model effective field theory,smeft,one loop calculations,collider physics,large hadron collider
Production of functional innovative ingredients from paper and agro-food side-streams through sustainable and efficient tailor-made biotechnological processes for food, feed, pharma and cosmetics (INGREEN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Public-private partnerships
Destination: Bio-based Industries
Action type: Innovation actions
Partnership: BBI (Art-187)
Countries involved: Ireland,Italy,Italy,Italy,Italy,Germany,Spain,Italy,Italy,Italy,Switzerland,Belgium,France,Netherlands,Portugal,United Kingdom,United Kingdom
Call: Produce sustainable and cost-efficient high-performance functional ingredients from alternative sources (H2020-BBI-JTI-2018, 2018)
Start date: 2019-06-01
End date: 2022-11-30
Duration (months): 42.0
Total project cost (EUR): 8775678.83
EU funding (EUR): 6323919.5600000005
Participants: 18
Project status: CLOSED

Agro-food and Paper mill side streams and by-products are sources of unexploited organic fractions exploitable into safe microbial biomasses, functional ingredients and intermediates, e.g. prebiotics, pre-fermented ingredients, bioplastics and chemicals. The INGREEN bio-based ingredients/materials will be used to produce innovative functional products for food, feed, packaging, pharmaceutical, nutraceutical and cosmetic sectors. The INGREEN outcomes will be obtained by validated tailor made biotechnologies based on safe microorganisms or eco-friendly approaches. Logistics and storage conditions will be optimized to favor the flow from feedstock to the bio-based prototype producers. INGREEN aims to demonstrate in industrial environments the efficiency and sustainability of the target biotechnologies to produce i) lactobionic acid (LBA), galactooligosaccharides (GOS), microbial safe biomasses from whey; ii) polyhydrohyalkanoates (PHA) enriched biomasses and purified PHA, as prebiotics and bioplastics respectively, from paper mill wastewater; iii) functional pre-fermented ingredients from rye/wheat milling fractions. Safe and characterized INGREEN ingredients will be used for innovative functional cheeses, bakery products and nutritious feeds. Functional GOS, LBA and pre-fermented bran will be used to produce prebiotic immune-stimulating gel, nutraceutical supplement and cleanser for human health. INGREEN biodegradable material will be valorised into bag in box to boost INGREEN fluid prototype sustainability. Prototype safety, shelf-life, quality and functional performances will be compared to benchmarks. Also LCA/LCC, sound business cases and plans and compliance with REACH and any relevant EU safety legislation will be applied over the whole project to assess prototype benefits compared to benchmarks. INGREEN product specifications will contribute to define/standardize the regulatory requirements for outcome innovation deals, market uptake and societal acceptance.

Keywords: biobased ingredients food by product food feed nutraceutical cosmetic prebiotics cheese bakery
Flourishing Seeds. Value Creation and Relatedness in Agrobiodiversity Hotspots (SeedsValues)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-02-01
End date: 2026-01-31
Duration (months): 60.0
Total project cost (EUR): 1447462.0
EU funding (EUR): 1447462.0
Participants: 1
Project status: SIGNED

AgricultureAgriculture condenses the most pressing challenges we are facing today: ecological degradation, financial deregulation and demographic explosion. Value discrepancies are key obstacles toward integrated agriculture which are not rewarding in the capitalist economy overwhelmed by a profit-driven agroindustry. However, we still lack fundamental knowledge to identify the manifold values of agricultural assets. While the value of crop varieties is usually assessed in economic terms, we need to also consider the ethical values that incentivies farmers to perpetuate biodiverse agriculture. Beside empirical timeliness, this study contributes to the elaboration of a general anthropology of value still lacking to date. The SeedsValues contends that agriculture offers a unique object to overcome the current split between the economic and the ethical studies on value. This will be achieved by producing interspecies ethnographies into seed-human relatedness - both affective and instrumental - in three agrobiodiversity hotspots: potato cultivation in Peru, maize in Mexico and rice in Laos. Prominent on global markets, also distinguished by international institutions as highly promising to reach global food security, these crops bear outstanding value to the Indigenous people who cultivate and eat them daily. Sometimes, they are treated as organisms imbued with a subjectivity, challenging Western dichotomies between object and subject, nature and culture. In this light, this project aims at unravelling (a) the ethics of seed growing, (b) the appreciation of seeds in exchange and consumption, and (c) the entanglements between growers' and seeds’ qualities. Beside addressing critical ecological questions regarding the sustainable feeding of an increasing human population, this research at the interface of anthropology and biology promises significant theoretical advances in the anthropology of value by investigating a vital object: the cultivation of flourishing seeds.

Keywords: interspecies relations,environmental care,commodification
Expansion microscopy in zebrafish embryo to study primary cilia function during cardiovascular development and diseases (ZEBREXPANSION)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-06-01
End date: 2023-05-31
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

This project aims at revealing the function of primary cilia during cardiovascular development and cardiovascular diseases, with a specific focus on cardiac valves, through an imaging approach based on expansion light microscopy. Cilia are evolutionary conserved organelles, involved in fundamental processes such as motility, signalling and mechano-sensing, associated with a group of developmental diseases termed ciliopathies. Cardiovascular defects are common in patients diagnosed with ciliopathies and genetic studies have identified mutations in genes coding for ciliary proteins in patient suffering from congenital heart diseases, suggesting an important role for this organelle in cardiogenesis. In particular, it has been shown that DZIP1, a cilia related protein involved in ciliogenesis, is mutated in patients. However, little is known about molecular mechanisms underlying DZIP1 abnormal function at developmental stages of valvulopathies. Using an innovative imaging-based approach in human ciliated cells and in zebrafish, we will investigate if cilia assembly, maintenance and disassembly are correlated with essential regulatory functions of DZIP1 during cardiogenesis, more precisely in endocardial cells (EdCs) during valvulogenesis. We will test if the protein DZIP1/Iguana function is not restricted to ciliogenesis in differentiated cells, but displays dynamic functions at centrioles and in the cytoplasm, that are important for tissue-remodelling. My multidisciplinary approach will allow me to tackle this question from the molecular and structural to the cellular and tissue-scale.

Keywords: zebrafish,cilia,expansion microscopy,light sheet,live microscopy