Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Key Environmental monitoring for Polar Latitudes and European Readiness (KEPLER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Coordination and support actions
Countries involved: Germany,Spain,Germany,Sweden,Finland,Sweden,Norway,Finland,Norway,France,Denmark,United Kingdom,United Kingdom
Call: Copernicus evolution – Mission exploitation concepts (H2020-SPACE-2018, 2018)
Start date: 2019-01-01
End date: 2021-06-30
Duration (months): 30.0
Total project cost (EUR): 2899156.46
EU funding (EUR): 2899156.46
Participants: 16
Project status: CLOSED

KEPLER is a multi-partner initiative, built around the operational European Ice Services and Copernicus information providers, to prepare a roadmap for Copernicus to deliver an improved European capacity for monitoring and forecasting the Polar Regions. Our motivation is to put the public and stakeholders at the centre of Copernicus. This follows the recommendations of the ‘Copernicus User Uptake’ review, and its 4 themes of: 1) Raising awareness for the Copernicus programme, 2) Informing and educating Copernicus users, 3) Engaging Copernicus users in public and private sector, and 4) Enabling access to Copernicus data and information. These well tailored themes form the core components of KEPLER. However, as the Polar Regions are changing, so too are the challenges and opportunities. Because of these shifts we have included two additional themes that encompass the evolving needs. These are needed to provide opportunities for better understanding the environment, research opportunities, establishing new industry sectors and startups, and importantly empowering citizens: 5) Identification of research gaps regarding integration/assimilation, and 6) Improved sea-ice mapping and forecasting. Through these 6 themes KEPLER aims to release the full potential of Polar Regions Earth Observation, including from ESA and EUMETSAT, by identifying and eliminating the barriers that impede the use of the tremendous resource that is Copernicus. This combines 2 key elements of the call: a) bringing together key European stakeholders and competent entities, and b) growing the Copernicus brand and user-base through providing enhanced scientific and technical support. Our objective with KEPLER is to provide a mechanism that enables the broad range of Polar Regions stakeholders to be equipped with the most accurate and relevant, environmental information so that they can seize the many benefits that Copernicus products generate for society and economy.

Keywords: polar regions,arctic,antarctic,operational monitoring,data assimilation,forecasting,climate,planning,copernicus,society,population
Operation Co-Pilot: Healthcare Process Improvement through Patient Empowerment (OpCo)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-07-01
End date: 2019-09-30
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In any medical treatment or procedure, the patient is / needs to be the key player. The result - and honestly cost - of a medical treatment is largely dependent on the successful interaction between all medical personnel and the patient. Effective communication, information, and education, empowers patients to be more active players in their own health. So far, this coordination of medical team and the patient is lacking, as demonstrated by a staggering 22% surgery cancelations due to patient’s pre-operative mistakes and 60% post-operative complications due to patients’ "contributory negligence". The result is further health issues for the patients and additional costs for Healthcare systems Operation Co-Pilot, OpCo, is a tool for Healthcare Process Improvement, in the form of a digital solution that brings together the complete process of a medical treatment with the patient perspective front and centre. OpCo provides personalized guidance to patients in full compliance with medical procedures of the clinics. patients are more secure (knowledge is the enemy of fear), motivated (with specific features to increase patient engagement) and responsible (feeling the power to take charge of their fate) – In a word, Empowered. OpCo has proven to engage close to 100% of the patients that are given access to it, that in turn creates efficiencies to the Health Care provider: 50% cancelation reduction, that allows to perform more surgeries on the year and 30% more available hospital beds over the duration of a year, as OpCo has proven to reduce average hospital stay from 3 to 2 nights. We have launched our solution in 6 orthopedic clinics and soon we’ll be launching in an Ob-Gyn clinic. in a short time, OpCo has shown its capability to help tackle the HC challenges of today and tomorrow. Now we are seeking to implement new capabilities to OpCo and expand to new areas with the mission to optimize healthcare through patient empowerment.
Electrogenic NItrate Reduction In marine Sediments (ENIRIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Belgium,Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-04-01
End date: 2018-04-24
Duration (months): 24.0
Total project cost (EUR): 163044.6
EU funding (EUR): 163044.6
Participants: 2
Project status: CLOSED

Recently, a novel type of long, filamentous bacteria has been discovered, which are capable of guiding electrical currents over centimeter distances. These so-called “cable bacteria” were first isolated from marine sediments, and laboratory experiments demonstrate that electrons are passed on from cell to cell along the longitudinal axis of the filaments. This long-distance electron transport radically extends the physiological capacities of prokaryotes, and profoundly changes our understanding of biogeochemical transformations in marine sediments. In my PhD research, I have documented that in addition to oxygen, these sulphur oxidizing bacteria can also use nitrate as an electron acceptor. This new form of “electrogenic” nitrate reduction could have important implications for the removal of bio-available N in marine ecosystems. However, the effect of this newly described nitrate reducing process on the global nitrogen cycle, as well as the factors that ultimately control the occurrence, remain unknown. The goal of this project is to identify the end products of the electrogenic nitrate reduction and the environmental controls that regulate its occurrence. This project will hence provide new insights into the physiological abilities of micro-organisms and improve our understanding of N dynamics in marine sediments, strengthening European excellence in these fields of research. The goals of the project will be attained by combining state-of-the-art biogeochemical techniques with a novel and interdisciplinary approach based on principles traditionally applied in microbiology, electrochemistry and geophysics. This project will allow me to work on an up-to-front topic and thus to build up a unique research profile among the large number of researchers in the of nitrogen cycling.

Keywords: nitrate,marine sediment,cable bacteria,denitrification,electric currents,microsensors
Role of Tumour Suppressor Gene Products of Common Fragile Sites in Human Diseases (TSGPs-of-CFSs)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Israel
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-05-01
End date: 2021-10-31
Duration (months): 66.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: CLOSED

Common fragile sites (CFSs) are large chromosomal regions identified by conventional cytogenetics as sequences prone to breakage in cells subjected to replication stress. The interest in CFSs stems from their key role in DNA damage, resulting in chromosomal rearrangements. The instability of CFSs was correlated with genome instability in precancerous lesions and during tumour progression. Two opposing views dominate the discussion regarding the role of CFSs. One school of thought suggested that genomic instability during cancer progression causes collateral damage to genes residing within CFSs, such as WWOX and FHIT. These genes are proposed to be unselected ‘‘passenger’’ mutations. The counter argument is that deletions and other genomic alterations in CFSs occur early in cancer development. Cancer cells with deletions in genes that span CFSs are then selectively expanded due to loss of tumour suppressor functions such as protection of genome stability, coordination of cell cycle or apoptosis. Recent observations from my lab clearly suggest that gene products from CFSs play driver roles in cancer transformation. Moreover, we have evidence for the involvement of DNA damage and Wwox in pancreatic β-cells in the context of diabetes. Here, I propose to investigate the role of tumour suppressor gene products (TSGPs) of CFSs in human diseases. Three approaches will be taken to tackle this question. First, molecular functions of TSGPs of CFSs will be determined using state-of-the-art genetic tools in vitro. Second, novel transgenic mouse tools will be used to study CFSs and their associated TSGs in preneoplastic lesions and tumours in vivo, with confirmatory studies in human material. Third, we will examine the potential involvement of CFSs and their TSGPs in type-2 diabetes (T2D). The expected outcome is a detailed molecular understanding of CFSs and their associated TSGPs in genomic instability as well as their roles in cancer and metabolic diseases.

Keywords: cancer mouse models,genomic instability,diabetes,wwox,fra16d
Rules of self-organization and reengineering of liver tissue (RULLIVER)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Cellular, Developmental and Regenerative Biology
Panel description: Structure and function of the cell, cell-cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Germany
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-10-01
End date: 2022-12-31
Duration (months): 75.0
Total project cost (EUR): 2498013.0
EU funding (EUR): 2498013.0
Participants: 1
Project status: SIGNED

We want to understand the rules of self-organization underlying tissue structure and function. To address this problem, we have chosen the mouse liver with its complex apico-basal polarity of hepatocytes and its unique 3D tissue organization. We aim at identifying the rules of self-organization of liver tissue and their implementation at the molecular level. Our ultimate goal is to demonstrate that it is possible to reengineer liver tissue structure. The first aim will be to develop a digital geometrical model of liver tissue, i.e. an accurate 3D digital representation of the cells, forming the tissue and their sub-cellular components, in the developing, adult and regenerating liver, and unravel the principles for how the cells are organized to generate liver cell architecture. In aims 2 and 3, we will identify the molecular mechanisms underlying such geometrical rules. In particular, the second aim will be to characterize the molecular mechanisms responsible for hepatocyte cell polarity and predictably modify cell organization in vitro. The third aim will consist of introducing genetic perturbations to alter hepatocyte cell organization (cell polarity) and cell-cell interactions to predictably modify the structure and function of liver tissue. The fourth aim will be to develop a physical model of liver tissue self-assembly and organization. The project is ambitious as it aims to understand the rules of tissue organization in 3D in a mammalian organ to such an extent that it is possible to make predictions of tissue response to genetic perturbations and reengineer it to modify its structural and functional properties.
Foundations and Applications of Functional Cryptography (FAFC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Israel
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-02-01
End date: 2023-01-31
Duration (months): 72.0
Total project cost (EUR): 1307188.0
EU funding (EUR): 1307188.0
Participants: 1
Project status: CLOSED

Modern cryptography has successfully followed an "all-or-nothing" design paradigm over the years. For example, the most fundamental task of data encryption requires that encrypted data be fully recoverable using the encryption key, but be completely useless without it. Nowadays, however, this paradigm is insufficient for a wide variety of evolving applications, and a more subtle approach is urgently needed. This has recently motivated the cryptography community to put forward a vision of "functional cryptography'': Designing cryptographic primitives that allow fine-grained access to sensitive data. This proposal aims at making substantial progress towards realizing the premise of functional cryptography. By tackling challenging key problems in both the foundations and the applications of functional cryptography, I plan to direct the majority of our effort towards addressing the following three fundamental objectives, which span a broad and interdisciplinary flavor of research directions: (1) Obtain a better understanding of functional cryptography's building blocks, (2) develop functional cryptographic tools and schemes based on well-studied assumptions, and (3) increase the usability of functional cryptographic systems via algorithmic techniques. Realizing the premise of functional cryptography is of utmost importance not only to the development of modern cryptography, but in fact to our entire technological development, where fine-grained access to sensitive data plays an instrumental role. Moreover, our objectives are tightly related to two of the most fundamental open problems in cryptography: Basing cryptography on widely-believed worst-case complexity assumptions, and basing public-key cryptography on private-key primitives. I strongly believe that meaningful progress towards achieving our objectives will shed new light on these key problems, and thus have a significant impact on our understanding of modern cryptography.

Keywords: cryptography,foundations,applications
Arena-Master Mobile Solution for Complete Synthetic Turf Recycling On-site (ARENA)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Estonia
Call: Boosting the potential of small businesses for eco-innovation and a sustainable supply of raw materials (H2020-SMEINST-1-2015, 2015)
Start date: 2015-07-01
End date: 2015-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Over 600 000 tonnes of rubber crumb, silica and polymers mixed wastes are generated from used artificial grass fields each year in Europe. Based on the current market trends the total market volume and waste generation will increase more than 5-times by 2022, causing a huge environmental impact. Despite the growing popularity and implementation of artificial grass fields, there are no unified regulations or procedures for its EOL management. Current recycling technologies enable only low-efficiency infill separation from the artificial grass that is also time consuming, expensive and unsustainable. Therefore, most field owners landfill the used turf without any recycling, creating a big environmental impact and increasing the need for raw materials in new installations. ASIE, company with over 20-years of experience in installing artificial grass fields, has developed the first mobile and complete artificial grass recycling line that helps to lower the synthetic turf EOL management costs by up to 40-50% and increase the artificial grass sustainable management recycling rates. Compared to alternative solutions, we ensure: • 2x better infill separation (100%) • 4x faster old turf removal (1 day) • 2x faster field renewal (7 days) • 30-40% cheaper field renewal Our goal is to achieve a zero-waste concept and improve the ecologic and economic sustainability of artificial grass installations. Our unique mobile technology enables to reuse about 95% of the used materials in new artificial grass application or as a raw material in other industries together with: • 100% infill materials and polyethylene reclaim • 4x better turf removal enabling re-installation • 6x reduced transportation needs, leading to 95% less CO2 emissions Our total addressable market in Europe is €350 million annually, with very high growth potential in the next years. As a result of the innovation project, ASIE will generate €25m annual revenue and create more than 50 new jobs by 2022.

Keywords: synthetic turf,artificial grass,eol management,materials reclamation and recycling
'AV-Ready' transport models and road infrastructure for the coexistence of automated and conventional vehicles (CoEXist)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Germany,Germany,Belgium,Sweden,Sweden,France,France,France,Netherlands,United Kingdom,United Kingdom
Call: Road infrastructure to support the transition to automation and the coexistence of conventional and automated vehicles on the same network (H2020-ART-2016-Two-Stages, 2016)
Start date: 2017-05-01
End date: 2020-04-30
Duration (months): 36.0
Total project cost (EUR): 3474067.5
EU funding (EUR): 3474067.5
Participants: 17
Project status: CLOSED

The mission of CoEXist is to systematically increase the capacity of road authorities of getting ready for the transition towards a shared road network with increasing levels of automated vehicles (AVs), both in terms of vehicle penetration rates and levels of automation using the same road network as conventional vehicles (CVs). CoEXist will enable mobility stakeholders to get “AV-ready” – which CoEXist defines as conducting transport and infrastructure planning for automated vehicles in the same comprehensive manner as for existing modes such as conventional vehicles, public transport, pedestrians and cyclists, while ensuring continued support for conventional vehicles on the same network. AV-ready transport and infrastructure planning in cities is a key precondition for fulfilling the promises of AVs to reduce road space demand and improve traffic efficiency and safety – without it, AVs could simply increase the urban mobility problems. CoEXist will address three key steps in transport and infrastructure development: • AV-ready transport modelling: Validated extension of existing microscopic and macroscopic transport models to include different types of AVs (passenger car/ light-freight vehicle, automation levels). • AV-ready road infrastructure: Tool to assess the impact of AVs on safety, traffic efficiency and space demand and development of design guidance for hybrid (AV-/CV-shared) infrastructure. • AV-ready road authorities: Elaboration of eight use cases in four road authorities (Gothenburg, Helmond, Milton Keynes and Stuttgart), used to evaluate AV impacts on safety, traffic efficiency and road space requirements (with CoEXist tools) and making detailed hybrid infrastructure design recommendations. Due consideration of CEDR’s Transnational Research Programme is shown through the participation of TRL, the coordinator of the CEDR-funded Dragon project.

Keywords: automated vehicles,transport modelling,hybrid road infrastructure
Advanced and smart system for optimizing the non-conformities and concession processes within the aerospace industry. (ZinkOn Growth)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Spain
Call: Small business innovation research for Transport (H2020-SMEINST-1-2015, 2015)
Start date: 2015-10-01
End date: 2016-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Due to the manufacturing process and the special requirements in the aerospace industry for the parts produced, usually there are some parameters out of tolerance, defects produced on the handling or transportation of the parts. These defects are highly common, leading a high percentage of discarded parts, i.e 5 - 10% of the total produced parts, or repair processes - between 10 to 20% of the parts have non-conformities - that are time and cost consuming. Similar situation occurs with in-services airplanes, where maintenance is a crucial activity and the ground time is highly important factor for the viability of the airline. Reducing the percentage of scrapped parts, the non-conformities solving time on the manufacturing or reducing the on-the-ground time for airline fleets becomes one of the main objectives of the engineering support teams. The average cost of per unit of non-conformity, considering an average lead-time of 6 days, will be 1.140€. It is estimated that the annual management cost for one of these non-conformities is around 350 million € per year in Europe. ZinkCloud, through its ZinkOn product, provides a solution (based on Artificial Intelligence and other cutting edge technologies) to eliminate the bottleneck processes related to the engineering tasks, addressing especially the non-conformities, and providing recommendations on how to repair some defects based on previous experiences, applicable documentation and regulations. Our product, validated as beta version in Spain by Airbus and other relevant players in the aerospace industry, is revolutionizing the way of managing nonconformities. ZinkOn is becoming a breakthrough innovation with potential to change the associated costs and managing times of these unavoidable manufacturing defects, in line with strategic objectives in the industry regarding a reduction on the production costs . We foresee an important growth: 40 new jobs and over 4,2M€ turnover by 2020.

Keywords: feasibility study,aircraft,aviation,non conformities,concessions