Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Nanocapsules for targeted delivery of radioactivity (RADDEL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,United Kingdom,United Kingdom,Italy,France,Spain,Greece,Czechia,France
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-02-01
End date: 2016-01-31
Duration (months): 48.0
Total project cost (EUR): 3849760.1
EU funding (EUR): 3849760.1
Participants: 10
Project status: CLOSED

The consortium RADDEL (RADioactivity DELivery) has a research-based approach for the training of the new generation of scientists in the development of novel functional nanomaterials . A well structured training program will be provided with a balanced combination of local and network-wide training through secondments, joint network meetings, workshops, schools, industrial training and the final network conference. The research program focuses on the design, synthesis, characterisation, pharmacological studies and dosimetry calculations of nanocapsules that seal in their interior radioactive materials for biomedical applications in the areas of cancer diagnosis and therapy. After sealing the chosen radionuclides, the external walls of the nanocapsules will be decorated with biomolecules to render them biocompatible and for targeting purposes. In a recent study we have recently observed that these nanocapsules allow the delivery of unprecedented radiodosage and remain stable for extended periods thus guaranteeing essentially zero leakage of the radionuclides. Surface functionalisation of these nanocapsules offers versatility towards modulation of tissue biodistribution of the radioemitting crystals in a manner determined by the nanocapsule that delivers them. The delivery of radioactivity takes place through the walls of nanocapsules (carbon) and release of the encapsulated radionuclides is therefore not needed and certainly not desired. The present research objectives go beyond the-state-of-the art in the field and innovative products and solutions are expected.

Keywords: carbon chemistry,nanotechnology,radiopharmaceutical technology,organic chemistry
Novel Statistical Methodology for Diagnostic/Prognostic and Therapeutic Studies and Systematic Reviews (MEDIASRES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Netherlands,United Kingdom,Switzerland,Denmark,Norway,Spain
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 3935114.0
EU funding (EUR): 3935114.0
Participants: 10
Project status: CLOSED

Novel statistical methodology promises to greatly facilitate development of approaches for personalised medicine. While state-of-the-art statistical techniques have already advanced clinical trials and diagnostic/prognostic studies as the major source of evidence in clinical medicine, increasing availability of molecular techniques holds an even greater promise. However, for leveraging such information for individualised diagnosis/prognosis, and treatment, the corresponding complex structures have to be adequately modelled and results have to be aggregated by corresponding advanced meta-analytic approaches. The main goal of the project is to establish a joint research-training programme by an interdisciplinary and intersectorial network for providing early-stage researchers with deep insight into cutting-edge statistical methodology. The research area of statistical methodology for diagnostic/prognostic and therapeutic studies and systematic reviews is well suited for early-stage training purposes, as it comprises a wide range of theoretical and applied biostatistical tools that need to be mastered, further developed, and translated into clinical research and practice. Europe-wide exchanges will also be ensured to meet the need for mobility in today’s globalised society. Further career relevant knowledge and skills will be provided through a structured design of education. The early-stage researchers will be trained according to an individually supervised, comprehensive and complementary programme. The structure of these activities is based on the training-through-research approach of the network. The collaboration of leading biostatistical experts will stimulate the discovery of promising statistical methodology useful for the design and analysis of clinical research. The integration of full industry partners and clinical advisors in the network enables optimal conditions for research driven by application, which will ensure tangible benefits of the programme.

Keywords: medical statistics,clinical trials,prognostic studies,event-history analysis,prediction,missing data,meta-analysis,knowledge translation
Best Training for Green and Silent Mobility (GRESIMO) (GRESIMO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Austria,Belgium,Germany,Italy,Slovenia,Germany,France
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2011-10-01
End date: 2015-09-30
Duration (months): 48.0
Total project cost (EUR): 3418118.0
EU funding (EUR): 3418118.0
Participants: 9
Project status: CLOSED

Engineering for future mobility must be inspired by ecology and economy to enable green and silent vehicles. Current university based education is focusing on classical fields like mechanical engineering on one side with some aspects of Noise, Vibration & Harshness (NVH) and Light Weight Design (LWD) or like electrical engineering covering aspects of “Electrification” & “Hybridisation” on the other side. The proposed GRESIMO project (Best Training for Green and Silent Mobility) aims to bring together early stage researchers and experienced specialists from across industry and academia in Europe covering NVH, LWD and H/E disciplines to form a broad range of professional background. Recent research underlines the strong interaction and shows the often conflicting demands of these 3 topics. Consequently, an optimum for future vehicle development requires an interdisciplinary education in this triangle of topics. GRESIMO focus is to motivate and encourage early stage researchers for scientific work in the new interdisciplinary research fields NVH+LWD, LDW+H/E and H/E+NVH. The fellows will be trained and supported in their phase of doctoral thesis to find innovative PhD topics as well as to receive specific education in theoretical and practical trainings. The education will comprise existing lectures in the partner network as well as training specifically developed for the interdisciplinary needs. GRESIMO is formed by a group of participating hosts, combining leading education and research institutions as well as industrial enterprises in 6 countries of the EC. Thus the engineers will participate in both the scientific research work and the practical application of new methods of testing and simulation. They will profit from extended international knowledge after their academic education when starting to work in the industry. Furthermore, the industry will gain from the specific training of the young researchers for the requirements to develop green and silent vehicle.

Keywords: physical sciences,acoustics,technological sciences,materials engineering,electroacoustics,applied physics
Engineering Tribochemistry and Interfaces with a Focus on the Internal Combustion Engine (ENTICE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,France,Slovenia,Netherlands,France,Austria,France,United Kingdom
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-02-01
End date: 2016-01-31
Duration (months): 48.0
Total project cost (EUR): 3369190.0
EU funding (EUR): 3369190.0
Participants: 9
Project status: CLOSED

The main aim of the ENTICE proposal is to provide professional development in the multidisciplinary field of ENgineering Tribochemistry and Interfaces for IC Engines, capable to develop the new generation of clean and energy-efficient engines. It aims to train the next generation of researchers to work in diverse teams, to cross disciplinary and sectoral boundaries and apply advanced communication and information technologies to work across many scales of time and space. Detailed project objectives are: 1. To provide scientific and professional development to a highly motivated group of early stage researchers (ESRs) to address a number of key interdisciplinary research issues of great importance to the future of transport industries. 2. To facilitate and support scientific and professional development of two experienced researchers (ERs) to enable them to become the research leaders in two challenging interdisciplinary research areas. 3. To disseminate the knowledge and products developed through scientific research to industry, policy makers and the wider academic community for maximum impact of the research. 4. To initiate a sustainable long-term research, training and educational collaboration between the partners involved. Here we propose the development of a training network that brings together some of the key active research groups in Europe, with a leading international reputation, in complementary areas relevant to the fields of tribochemistry and interface design. A number of leading industrial companies, comprising of SMEs and LEs, will engage in training and facilitate the Transfer of Knowledge (ToK) to and from the industrial partner through research programmes for 12 ESRs and 2 ERs. The training programme proposed comprises two key elements; generic training to cover aspects of training required for future research leaders in academia and industry and on-the-job training which will include specialised project-specific skills and development.

Keywords: materials engineering,spectrochemistry,surface chemistry,surface physics,intelligent interfaces,measurement technology
New Generation of Functional Cellulose Fibre Based Packaging Materials for Sustainability (NEWGENPAK)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Sweden,Poland,Spain,United Kingdom,Italy,France,Germany,Denmark,Netherlands,United Kingdom
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2011-12-01
End date: 2015-11-30
Duration (months): 48.0
Total project cost (EUR): 3190329.03
EU funding (EUR): 3190329.03
Participants: 12
Project status: CLOSED

The NEWGENPAK ITN is an interdisciplinary research training network of 8 European universities, 3 research institutes and 6 enterprises, three of which are Full partners. Its primary aim is to create a European training network designed to improve the career prospects of its 10 ESRs and 2 ERs in both the public and private sector. The network will deliver a joint multidisciplinary research training programme which will encourage and foster the growth of the researchers’ skills in scientific expertise, technological knowledge and professional aptitude. The key vehicle in this strategy is a supervised personal, original research project in a critical aspect of sustainable packaging. The network has been designed to achieve the following objectives (i) to conduct top-level research and training and devise innovative solutions for specific EU needs in the area of sustainable packaging, (ii) to advance the state-of-the-art in wood cellulose based sustainable packaging in three specific areas (a) next generation packaging composites, (b) cellulose-fibre based active packaging and (c) environmental, economic and societal aspects of packaging production, (iii) to educate the next generation of researchers inside a broad European research training network which includes universities, research centres and industry, thereby accelerating the researchers’ advancement to team leader status, (iv) to improve the career prospects of ERs and ESRs through complementary training such as; writing and presentation skills; language, effective communication and collaboration; project management and finance; project/product cycles; entrepreneurship; IPR, (v) to create an integrated, long-term sustainable packaging research and training base in the EU by bringing together universities, research institutes and industrial players active in key research disciplines.

Keywords: non-wood forest products,paper technology,active packaging,biopolymers,cartonboards,life cycle assessment,nano celluloses,nano clays,nano composites,packaging
Studying Physiology and Pathology of Imprinted Genes to understand the role of Epigenetic Mutations in Human Disease (INGENIUM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy,United Kingdom,United Kingdom,United Kingdom,France,Switzerland,Denmark,Spain,Belgium
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-04-01
End date: 2016-03-31
Duration (months): 48.0
Total project cost (EUR): 3662880.0
EU funding (EUR): 3662880.0
Participants: 10
Project status: CLOSED

The aim of this ITN is to promote research and training in the field of epigenetics associated with human disease. Expression of imprinted genes is mono-allelic and gamete of origin-dependent. This is due to different epigenetic modifications present on the maternal and paternal chromosomes. Failure in normal establishment, maintenance or erasure of these marks results in gene dosage dysregulation and Imprinting Disorders (IDs). This ITN brings together different expertise from both public and private sectors with the aim of investigating the physiology and pathology of Genomic Imprinting. We propose to define mechanisms, molecular factors and pathways regulating DNA-methylation and chromatin dynamics involved in gene expression control in human health and disease. This concerted approach has the potential to identify new and more effective diagnostic, preventive and therapeutic strategies for IDs, and more generally to elucidate roles and origin of epigenetic mutations in human pathologies, including common diseases. Early stage (ESRs) and experienced researchers (ERs) will have access to a range of cutting-edge methodologies to enable the application of integrated multidisciplinary strategies to analyse epigenetic phenomena. The excellent scientific and educational environment and the intense public-private sector collaboration will promote high-level training of the young researchers. The ESRs and ERs will acquire experience and expertise in a variety of disciplines, including molecular, cellular and developmental biology, genomics, bioinformatics, chromatin dynamics and epigenetics and phenotypic analysis, and state-of-the-art methodologies such as gene targeting, stem cell culture, epigenetic and chromatin technologies, and massively parallel sequencing. Hence, this ITN will generate a new cohort of scientists trained in contemporary post-genomic biology and able to apply advanced technological tools to investigate human disease in both academia and industry.

Keywords: epigenetics,imprinting,medical genetics,dna methylation,chromatin analysis,high-throughput genomic analysis,stem cells,gene regulation
Reconstructing Mediterranean-Atlantic exchange during the Miocene (MEDGATE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,Spain,Spain,Netherlands
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-02-01
End date: 2016-01-31
Duration (months): 48.0
Total project cost (EUR): 2692902.0
EU funding (EUR): 2692902.0
Participants: 5
Project status: CLOSED

MEDGATE combines the expertise of 29 geoscientists from both the oil industry and academia in the training of 10 researchers. It aims to equip these researchers for successful careers in either sector through interdisciplinary projects focussing on an intriguing problem which has implications for both environmental change and hydrocarbon exploration. The research aim of MEDGATE is to reconstruct the evolution of the marine corridors that linked the Atlantic and Mediterranean prior to the formation of the Gibraltar Straits about five million years ago. Closure of these gateways led to catastrophic changes in Mediterranean sea-level and salinity and to the formation of hydrocarbon accummulations. Despite decades of research, the exact timing of closure, the geometry of the corridors and the pattern of exchange through them, remains uncertain. Previous work has been conducted mainly using single research methodologies. The MEDGATE project provides a unique opportunity to undertake a suite of ten interdisciplinary projects that integrate state-of-the-art technologies, surface and subsurface datasets and expertise supplied by both academic and industrial partners. These new data will clarify the environmental impact of gateway exchange and help assess the petroleum potential of the region. MEDGATE network-training programme will support the skill requirements of each project and foster interdisciplinary collaboration. It also emphasises training in advanced field geology and biostratigraphy, to address the declining skill levels in geoscience graduates reported by MEDGATE’s industrial partners. All eleven participating institutions will contribute substantially to network-wide technical and complementary skills training and each institution has committed to seconding one or more researchers. This will provide them with access to the expertise, facilities and experience they require to carryout their project and launch them on a successful geoscience career.

Keywords: geochemistry,mediterranean-atlantic gateways,messinian salinity crisis,interdisciplinary,biostratigraphy,modelling,field geology,subsurface geology,palaeogeography,hydrocarbon exploration
Rheumatoid Arthritis and Periodontal Inflammatory Disease (RAPID) (RAPID)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Sweden,Poland,Germany,Germany,Spain,United Kingdom,Spain,Netherlands,United Kingdom,Norway,United Kingdom
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-04-01
End date: 2016-03-31
Duration (months): 48.0
Total project cost (EUR): 4312151.08
EU funding (EUR): 4312151.08
Participants: 14
Project status: CLOSED

The most prevalent chronic inflammatory diseases of humans are complex disorders of multifactorial aetiology influenced by genes, the environment and their interactions. Periodontitis (PD) and rheumatoid arthritis (RA) are two such chronic inflammatory diseases associated with significant morbidity and mortality, and have recently shown to have a bi-directional association. Moreover, the prevalence of both increases substantially with age, and given both the Europe-wide ageing population and the impact of both diseases upon the economy, health and quality of life, it is clear that novel and more cost effective approaches to management are urgently required. A key research goal of this project is to improve understanding of the pathogenesis of RA and PD and their inter-relationships, through the study of common risk factors linked to the activation of host and bacterial derived protein citrullination, which subsequently generates pro-inflammatory auto-antigens in the joints and periodontal tissues. Our vision is that enhanced biological understanding in this area will inform the future development of new approaches to disease prevention, early diagnosis and novel therapies. RAPID aims to provide a significant contribution to this by establishing a first class, dynamic training network of 12 partners and 5 associated partners for early career researchers who will be able to advance chronic inflammatory disease research by working across sectors and disciplines. The network is an interdisciplinary cooperative of medical and dental clinicians, epidemiologists, bio-scientists, industrial scientists, media and commercialization specialists. The aim of the Training Programme is to increase the knowledge base and experience of trainees in the different research areas and to develop their transferable skills for future careers in industry or academia, whilst advancing the field through new discovery.

Keywords: health sciences,rheumatology,odontology,inflammatory diseases
Innovation for Digital Fabrication (DIGINOVA)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Coordination and support actions
Countries involved: Germany,United Kingdom,Germany,Portugal,United Kingdom,United Kingdom,United Kingdom,Norway,United Kingdom,Netherlands,Germany,Finland,Spain,United Kingdom,Netherlands,Netherlands,Netherlands,United Kingdom,Germany
Call:  (FP7-NMP-2011-CSA-5, 2011)
Start date: 2012-03-01
End date: 2014-02-28
Duration (months): 24.0
Total project cost (EUR): 1676173.5
EU funding (EUR): 1265785.0
Participants: 22
Project status: CLOSED

Most products are produced by means of the established mass production infrastructure. Traditionally, this involves large stocks, high manual labor, large capital investments, high energy use, long distance transportation. Although many advanced new materials have unique functional properties that hold a great promise for innovation, they often need to meet the criteria and characteristics of this established mass production paradigm. This delays the exploitation of the huge potential of whole new classes of materials. Combined with major societal trends and consumer needs like customization, personalization, on-demand fulfillment and the fact that the world is becoming ever more digital and networked, there is a need for a paradigm shift in manufacturing called Digital Fabrication. **Digital Fabrication can be defined as a new kind of industry that uses computer-controlled tools and processes to transform digital designs and materials directly into useful products.** DIGINOVA will establish the current status across material domains and application domains in Europe in order to identify the most promising technology and business propositions for Digital Fabrication. The project consortium, consisting of 4 large companies, 7 SMEs and 9 research institutes will identify and connect main stakeholders through establishment of innovation networks centred around concrete business cases to determine the added value and feasible routes to commercialization. The DIGINOVA consortium has broad research and development experience covering a wide range of materials and applications. The consortium is well equipped to generate international interest and expanding participation in the opportunities it identifies and has a proven track record in drafting roadmaps, establishing networks, involving stakeholders and informing the public at large. The DIGINOVA project will last 24 months and requests EU contribution of € 1.265.785.

Keywords: additive manufacturing,digital fabrication,printing,manufacturing,functional materials,printed electronics,digital,customization,rapid manufacturing,digital revolution