Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Bright AR - a Quantum Light Chip enabling augmented reality for everyday use (Bright AR)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Austria
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499999.0
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Bright AR - a Quantum Light Chip enabling augmented reality for everyday use Augmented Reality (AR) and its see-through glasses have the transformative potential to redefine the way we consume content and information. However, for see-through AR glasses to truly transform our daily lives, they must maintain high brightness to ensure digital content is as visible in the glaring sunlight as it is in artificial lighting, e.g. shopping malls or offices. For wide consumer adoption, AR devices must seamlessly transition between these environments, functioning as a practical, all-day wearable, assisting tool. However, this is not possible with current technologies. VitreaLab is developing the first AR light engine featuring a laser-illuminated LCoS display (Liquid Crystal on Silicon). It is a next-generation light engine able to provide good visual performance (high brightness, large field of view, high resolution, overall good image quality) in hardware suitable for wearables (small, with long battery life) at affordable prices. Vitrealab will enable manufacturers of AR glasses to create high-quality wearables for widespread, seamless, user-friendly everyday use. Our ambition is to gain a major foothold in the AR display market valued at over €15Bn by 2030. VitreaLab is a spin-off from the University of Vienna. With its first-of-its-kind photonic chip, VitreaLab offers an opportunity for the EU to increase its global market share in photonics. During the EIC project, we plan to integrate our AR light engine into commercial AR glasses and establish semi-automated production. After the grant, we will launch professional AR products and introduce a consumer-grade AR light engine, aiming to secure large orders through validation with manufacturers and scale-up with automated manufacturing processes.

Keywords: augmented reality glasses,light engine,laser ar light engine,laser lcos display,laser ar projector,laser illumination
Trusted Extremely Precise Mapping and Prediction for Emergency Management (TEMA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: World-leading Data and Computing Technologies
Action type: Research and Innovation actions
Countries involved: Greece,Germany,Italy,Spain,Netherlands,Finland,Belgium,Austria
Call: Methods for exploiting data and knowledge for extremely precise outcomes (analysis, prediction, decision support), reducing complexity and presenting insights in understandable way (RIA) (HORIZON-CL4-2022-DATA-01, 2022)
Start date: 2022-12-01
End date: 2026-11-30
Duration (months): 48.0
Total project cost (EUR): 11340223.75
EU funding (EUR): 11340223.5
Participants: 23
Project status: SIGNED

TEMA will greatly improve Natural Disaster Management (NDM, e.g., for wildfires, floods) by automating precise semantic 3D mapping and disaster evolution prediction to achieve NDM goals in near-real-time. It will analyze and fuse many heterogeneous extreme data sources: smart drone and in-situ sensors, remote sensing data, topographical data, meteorological data/predictions and geosocial media data (text, image and videos). TEMA will focus on the extreme nature of the data, due to their varying resolution and quality, very large volume and update rate, different spatiotemporal resolutions and acquisition frequencies, real-time needs and multilingualism. It will develop an integrated, ground-breaking NDM platform, focusing on real-time semantic extraction from multiple heterogeneous data modalities and sources, on-the-fly construction of a meaningful semantically annotated 3D disaster area map, prediction of disaster evolution and improved communication between service providers and end-users, through automated process triggering and response recommendations. Semantic analysis computations will be distributed across the edge-to-cloud continuum, in a federated manner, to minimize latency. Extreme data analytics will be performed in a trustworthy and transparent way, by greatly advancing state-of-the-art AI and XAI approaches. The constantly updated 3D map and the disaster evolution predictions will form the basis for an advanced, interactive, Extended Reality (XR) interface, where the current situation will be visualized and different response strategies will be dynamically evaluated through simulation by NDM personnel. The innovative, scalable and efficient TEMA platform will provide precise NDM support, based on extreme data analytics. It will be validated on two critical disaster use-cases (wildfires and floods), in four EU countries, and will form the basis for the TEMA NDM-Analytics-as-a Service (NDM-AaaS) model.

Keywords: augmented reality federated computing explainable ai ai robustness deep neural networks natural disaster management social media analysis real time semantic visual analysis earth observation
Portuguese Aljamia in Light of Maghrebi Vernacular Arabic (PoMar)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain,Portugal
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-04-16
End date: 2028-04-15
Duration (months): 24.0
Total project cost (EUR): 209914.56
EU funding (EUR): 209914.56
Participants: 3
Project status: SIGNED

This research seeks to address a significant gap in the study of Aljamia—Romance languages written in Arabic script. Unlike the numerous Aljamiado texts produced by Moriscos in Spain, the Portuguese Aljamia corpus consists of only eight known samples, compiled into a small notebook preserved in the National Archive of Torre do Tombo. These texts are believed to be versions of 16th-century Portuguese correspondences, translated from Middle Arabic originals, many attributed to Yahya U-Ta‘fuft (Bentafuf), a Berber leader serving King Manuel I during the Portuguese presence in Morocco in the early modern period. Despite partial editions, these documents have never been compiled into a full critical edition. The proposed edition aims to address long-standing questions, such as the authorship of these Aljamia texts and the function of using Arabic script for Portuguese. An interdisciplinary approach will enable a comprehensive analysis, combining philological and palaeographic examinations with Arabic linguistics, while situating the texts within the historical context of Portuguese expansion in North Africa. Central to this framework is the role of Maghrebi vernacular Arabic, as the texts exhibit significant influences from spoken Arabic varieties, which likely shaped both the translations and script choices. The project also highlights the role of Arabic-Portuguese translators, often Jewish intermediaries—such as the Benzamerro family—based in Atlantic coastal cities like Safi, Azemmour, and Mazagan. Finally, the study will explore translation choices from vernacular Arabic into Portuguese—written in both Latin and Arabic scripts—focusing on omissions, calques, loans, and additions. Through a critical edition of all versions of these texts, this research aims to clarify questions of authorship and highlight the linguistic varieties involved: 16th-century Portuguese and Middle Arabic, influenced by Maghrebi vernacular forms.

Keywords: aljamia,middle arabic,moroccan arabic,yahya bentafuf,torre do tombo,morocco under portuguese rule,jewish translators,palaeography,arabic manuscripts,portuguese philology
Unraveling the regulatory networks in Streptomyces that switch on antibiotic production on demand (COMMUNITY)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Biotechnology and Biosystems E ngineering
Panel description: Biotechnology using all organisms , biotechnology for environment  and food applications, applied plant and animal sciences , bioengineering and synthetic biology , biomass and biofuels , biohazards
Countries involved: Netherlands
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 3343206.0
EU funding (EUR): 3343206.0
Participants: 1
Project status: SIGNED

As Nature's medicine makers, Streptomyces bacteria produce a plethora of natural products, which we harness for clinical, biotechnological and agricultural applications, including 70% of the antibiotics. Streptomycetes still have a vast reservoir of unexplored biosynthetic potential, but many biosynthetic gene clusters (BGCs) are not expressed in the laboratory. To bring the chemical dark matter to the light, we need to discover the keys to unlock the expression of cryptic BGCs. I aim to add an entirely new dimension to genome mining, namely via understanding and exploitation of the regulatory networks that control natural product biosynthesis in Actinobacteria. My team discovered the concept of antibiotic production on demand, showing that plant hormones activate antimicrobials. Predicting when instead of what BGCs produce will allow clustering of BGCs based on their response to ecological signals. This can serve as a beacon for prioritising BGCs, and aid in the discovery of new biosynthetic pathways. I will tackle three major challenges: [1] The systems biology challenge is to elucidate the regulatory circuitry of streptomycetes and to reliably predict how BGCs are controlled [2] The metabolic challenge is to unwire the networks that tie carbon metabolism to antibiotic production, to bridge the gap from the complex polysaccharides in nature to the defined carbon sources of the laboratory. [3] The ecological challenge is to unravel the mechanisms and molecules via which plants invoke the power of Streptomyces' bioactive molecules to obtain protection against infections and pests, aimed at biological disease-suppression. COMMUNITY is an open science project that will help to elucidate whether the yet unexplored BGCs will deliver a paradigm shift in drug discovery, for application in agriculture and human health. Deliverables are innovative systems biology tools and detailed transcription factor networks, elicitors for drug screening and disease-suppressive microbes.
Continuous sub-mK refrigeration by demagnetization of atomic nuclei (NewCooler)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2023-03-01
End date: 2024-08-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The proposed ERC PoC project is to construct the first continuous nuclear demagnetization refrigerator (CNDR). Reaching temperatures near 10 mK has become relatively easy in the last decade. This cryogenic advance has driven an explosion in industrial efforts to build quantum computers based on superconducting qubits as well as rapid progress in fundamental physics experiments around 10 mK. However, cooling condensed matter below 1 mK remains challenging. Furthermore, there is no continuous cooling technology at this temperature. The CNDR will solve this problem by maintaining the sample temperature below 1 mK indefinitely while providing a large experimental space and eliminating the need for a liquid helium supply. We expect the CNDR to allow rapid investigation of qubits whose coherence is enhanced at temperatures << 10 mK and to propel work in fields ranging from nanomechanics to topological superconductivity.
European Lighthouse on Secure and Safe AI (ELSA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: A human-centred and ethical development of digital and industrial technologies
Action type: Research and Innovation actions
Countries involved: Germany,France,Italy,Spain,Switzerland,United Kingdom,Finland,Sweden
Call: European Network of AI Excellence Centres: Pillars of the European AI lighthouse (RIA) (HORIZON-CL4-2021-HUMAN-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 7434058.75
EU funding (EUR): 7434058.5
Participants: 26
Project status: SIGNED

In order to reinforce European leadership in safe and secure AI technology, we are proposing a virtual center of excellence on safe and secure AI that will address major challenges hampering the deployment of AI technology. These grand challenges are fundamental in nature. Addressing them in a sustainable manner requires a lighthouse rooted in scientific excellence and rigorous methods. We will develop a strategic research agenda which is supported by research programmes that focus on “technical robustness and safety”, “privacy preserving techniques and infrastructures” and “human agency and oversight”. Furthermore, we focus our efforts to detect, prevent and mitigate threats and enable recovery from harm by 3 grand challenges: “Robustness guarantees and certification”, “Private and robust collaborative learning at scale” and “Human-in-the-loop decision making: Integrated governance to ensure meaningful oversight” that cut across 6 use cases: health, autonomous driving, robotics, cybersecurity, multi-media, and document intelligence. Throughout our project, we seek to integrate robust technical approaches with legal and ethical principles supported by meaningful and effective governance architectures to nurture and sustain the development and deployment of AI technology that serves and promotes foundational European values. Our initiative builds on and expands the internationally recognized, highly successful and fully operational network of excellence ELLIS (European Laboratory for Learning and Intelligent Systems). We build ELSA on its 3 pillars: research programmes, a set of research units, and a PhD/postdoc programme, thereby connecting a network of over 100 organizations and more than 337 ELLIS fellows and scholars (113 ERC grants) committed to shared standards of excellence. We will not only establish a virtual center of excellence, but all our activities will be also inclusive and open to input, interactions and collaboration of AI researchers and industrial partners in order to drive the entire field forward.
Connected Hubs in Ageing: Healthy Living to Protect Cerebrovascular Function (CHAngeing)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Portugal,Greece
Call: Excellence Hubs (HORIZON-WIDERA-2022-ACCESS-04, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 4999693.75
EU funding (EUR): 4999693.75
Participants: 8
Project status: SIGNED

Cerebrovascular diseases (CVD) represent a major public health burden in Europe, afflicting, in particular, Easter Widening Regions. By bringing together a multidisciplinary and cross-sector agenda, CHAngeing will transform and interconnect two quadruple helix-based excellence ecosystems located in southern Europe (Portugal and Greece). This will be accomplished by science-based interventions: 1) promoting healthy lifestyles supported by Mediterranean diet culture to prevent CVD; 2) improving health technology-based rehabilitation of stroke patients. The objectives of CHAngeing are aligned with call outcomes, are supported by the Smart Specialization Strategy (RIS3) of both regions, and will contribute to deliver impact in both hubs and between hubs, in a synergistic manner: 1) reinforcing the excellence of both hubs as poles of attraction of new talents; 2) developing a common R&I strategy on ageing research, supported by action and investment plans; 3) promoting a culture of cross-sector fertilization in R&I and student’s training in both regions and across regions; 4) building strong links between research and business, filling innovation gaps and foster knowledge transfer and job creation; 5) implementing pilots and demonstrators towards healthy lifestyles and rehabilitation of stroke patients; 6) efficiently communicate, disseminate and exploit results of CHAngeing, ensuring high societal impact and long-term sustainability. The proposal encloses seven work packages: WP1- Coordination and management; WP2- Exploitation and sustainability (action and investment plans); WP3- R&I strategy; WP4- Advanced training and twinning; WP5- Connecting academia & business; WP6- Pilots & demonstrators; WP7- Communication, dissemination and societal impact. CHAngeing will be a catalyser of excellence synergistically supported by the success of established flagship projects in both regions, including Teaming for Excellence, ERA Chairs, Twinning, ERC’s, REGPOT, AAL and EIT Health

Keywords: healthy lifestyles disease prevention mediterranean diet culture cerebrovascular diseases stroke health technologies quadruple helix innovation ecosystems widening regions excellence hubs
Reprogramming cancer cells in dendritic cells to expand tumor-reactive infiltrating lymphocytes. (ExpandTILs)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 236340.0
EU funding (EUR): 236340.0
Participants: 1
Project status: SIGNED

Cancer affects 2.6 million people each year in the European Union, making it the second leading cause of death. Immunotherapies have revolutionized the treatment of cancer, seeking to re-arm immune cells against tumors. However, current immunotherapies are mostly inefficient in low immunogenic and solid tumors, which account for more than 80% of cancers in adults. A promising approach is to collect tumor infiltrating lymphocytes (TILs) from patient’s resected tumor tissue, and expand their function in vitro before reinjecting them to achieve antitumor immunity. This therapy is currently involved in many clinical trials and received a first FDA approval in 2024 for advanced melanoma treatment. Yet, a major challenge remains to amplify the diversity of tumor reactive TILs rather than the non-specific TILs. The aim of the ExpandTILs project is to selectively amplify tumor-reactive TILs to enable personalized, targeted and effective tumor killing. I will use the unique system designed by the host team, reprogramming the patient tumor cells into antigen presenting dendritic cells, to amplify tumor reactive TILs. I will establish an optimized coculture protocol with reprogrammed cancer cells to expand antigen-specific TILs, then train in cutting-edge techniques to characterize and compare their antitumor efficacy to standard-of-care TILs. This interdisciplinary approach, combining cellular reprogramming with cancer immunology, will increase our knowledge about tumor-specific TILs responses and allow us to obtain the proof-of-concept for a tumor reactive TILs expansion platform. This should lead to the creation of a new company, allowing me to learn how to bring new technologies to clinic. Therefore, this fellowship will significantly contribute to my professional growth by allowing me to develop complementary skills in project management, leadership, communication, and entrepreneurship.

Keywords: immunotherapy,adoptive cell transfer,tumor infiltrating lymphocyte,dendritic cell,neoantigens,cell reprogramming,cancer immunology
Cyanobacterial glycolipids as tracers of continental climate change (CYANITE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-02-01
End date: 2028-01-31
Duration (months): 60.0
Total project cost (EUR): 2284012.5
EU funding (EUR): 2284012.5
Participants: 2
Project status: SIGNED

Global surface temperatures are increasing in a manner unprecedented in modern Earth history. The extent of future warming on regional to global scales is difficult to predict but crucial for developing climate-resilient pathways and strategies for adaptation and sustainability. The study of ancient climates allows a mechanistic exploration of the Earth system and the opportunity to quantitatively and qualitatively evaluate and improve new generations of climate models. Particularly on the continents, however, the spatiotemporal reconstruction of ancient climates is often associated with large uncertainties due to the scarcity of proxy records. CYANITE takes an innovative approach to fill the ‘proxy record’ gap by tapping lacustrine sediment deposits as high-resolution archives of continental climate change. This will, for the first time, be feasible by the PI’s recent discovery of a novel suite of lipids, known as heterocyte glycolipids (HGs), that are ubiquitously present in lakes worldwide. CYANITE will interrogate the sensitivity of HGs to climate forcing in space and time and will develop, validate and apply HG-based lipid palaeothermometers that will provide essential new insights on the magnitude and timing of past continental climate change. CYANITE will go beyond the current state-of-the-art and through an integrated approach deliver i) culture and sediment calibrations to transfer HG-based proxy values to absolute temperatures and ii) high-resolution Cenozoic proxy records of continental climate change to facilitate palaeoclimate model-data comparison. As such, CYANITE will open new pathways in palaeoclimate research and significantly advance our capabilities to reliably forecast future climate change.

Keywords: cyanobacteria,lipid palaeothermometer,biomarkers