Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Decoupling IT? A Global Comparative Ethnography of the Role of IT in the Mitigation of the Climate Crisis (DecouplingIT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Denmark
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-11-01
End date: 2027-10-31
Duration (months): 60.0
Total project cost (EUR): 1999266.0
EU funding (EUR): 1999266.0
Participants: 1
Project status: SIGNED

Climate change is one of the biggest existential issues of our time, and there is little global agreement on how to deal with it. Governments and private sector industries argue that ‘decoupling’ economic growth from carbon emissions is the best way to reduce climate impact while still maintaining a healthy economy. Yet, how to do so remains an unsolved question. Most proponents of decoupling see IT as playing a central role, whereas critics argue that IT itself is entangled with incessant capitalist growth and has a large and often unacknowledged climate impact. In addition, IT solutions frequently have the side-effect of creating new and unforeseen problems – social or climatic. The challenge of decoupling is thus broader than the management of the relationship between the economy and the climate. As much as decoupling is about how we imagine the climate crisis can be solved with technologies, trusting that they can create the changes we need, it is also about the cultural value of lifestyles that we do not want to change. The DecouplingIT Project thus approaches decoupling as a matter of how sociocultural change is generated in the spaces between IT, climate change and capitalism. We study these spaces through ethnographic explorations of how IT professionals and enterprises articulate climate change as a problem in demand of IT-generated change, and in particular how they practically deploy IT with the climate in mind. While both climate change and IT are manifested in globally diverse ways, their interrelationship must be studied comparatively with attention to how particular conditions in different locations give rise to disparate responses. Consequently, we conduct research in distinct but conceptually connected ‘climate-IT-hubs’ each facing climate change in their own ways. This addresses a major theoretical gap in qualitative social science research, namely how global change is driven through the intersecting roles of IT, climate change and capitalism.

Keywords: anthropology climate change information technology change value capitalism
European Media and Immersion Lab (EMIL)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: A human-centred and ethical development of digital and industrial technologies
Action type: Innovation actions
Countries involved: Finland,Germany,Spain,United Kingdom
Call: Innovation for Media, including eXtended Reality (IA) (HORIZON-CL4-2021-HUMAN-01, 2021)
Start date: 2022-09-01
End date: 2025-06-30
Duration (months): 34.0
Total project cost (EUR): 7449850.0
EU funding (EUR): 7449850.0
Participants: 4
Project status: SIGNED

EMIL, the European Media and Immersion Lab, is a joint effort of four major European academic institutions (Aalto University, Filmakademie Baden Württemberg, Universitat Pompeu Fabra and University of Bath) to form a Pan-European XR Lab network to accelerate development of virtual, augmented and mixed reality technologies, content, services and applications for the media. EMIL will establish a physical and virtual infrastructure (EMIL Nodes), supported by research excellence, technological, creative expertise and wide contact networks to bring together interdisciplinary actors in the XR-field; engineers, designers, journalists, filmmakers, game developpers, programmers, artists, researchers, entrepreneurs and investors, from start-ups, SME’s and global corporations. EMIL will launch and coordinate FSTP projects and support this interdisciplinary community to accelerate XR-development all across Europe. The projects will be prototyping advanced solutions for the creation, distribution and consumption of new immersive and innovative products for media and related creative industries. FSTP projects can tap into the latest scientific research knowledge demonstrated in the EMIL nodes’ Lighthouse projects that exhibit excellence in Narrative Media Production, Smart Garments, Animation, VFX, Embodied Interaction, Digital Cultural Heritage, Digital Health, Motion Capture/Analysis, and technological XR-development. The FSTP projects and Lighthouse projects will quickly provide concrete cutting-edge products and services for the benefit of the European Media industry. However, EMIL’s true ambition and impact lie beyond the limitations of these projects and in the establishment of a permanent Pan-European XR network and community that will continue bringing new innovations in media, virtualization, computational design, interactive AI, resilient cities, manufacturing, and healthcare technologies and help Europe to be at the forefront of the next digital development revolution.

Keywords: virtual reality extended reality creative industry media broadcasting games mixed reality smart garment fvx avatar ai xr application xr tool third party project haptic interaction
Validated non-invasive liquid biopsy tests for cancer PREDIction in LYNCH Syndrome (PREDI-LYNCH)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Cancer
Destination: Cancer
Action type: Innovation actions
Countries involved: Norway,Finland,United Kingdom,France,Portugal,Netherlands,Spain,Latvia,Italy,Croatia,Czechia,Germany,Belgium,Sweden,Slovakia,Switzerland
Call: Accessible and affordable tests to advance early detection of heritable cancers in European regions (HORIZON-MISS-2024-CANCER-01, 2024)
Start date: 2025-05-01
End date: 2031-04-30
Duration (months): 72.0
Total project cost (EUR): 14035104.5
EU funding (EUR): 13606320.25
Participants: 28
Project status: SIGNED

We propose an ambitious yet well-conceived and deliverable pan-European, pan-cancer, pan-disciplinary, and multi-omic approach to address the pressing unmet need for an accurate, non-invasive, acceptable and cost-effective method of detecting precancerous and early-stage cancers in those individuals with Lynch syndrome (LS), the most common monogenetic increased hereditary cancer risk. LS has historically been underfunded and underserved, leading to significant an inequality in access and treatment. As a result, LS carriers have suffered needless cancers and deaths as a result. Our consortium has brought together the leading European experts, biotechnology companies and patient advocates to guarantee deliver practice-changing results that can be rapidly upscaled and adopted across the European Union and globally. Using an innovative clinical trial design, we will evaluate several multiple promising, non-invasive, liquid biopsy-based technologies in the three most common LS cancer types for an early-stage cancers detection. By leveraging Artificial intelligence (AI), we will identify traces of cancer, ensuring applicability to diverse healthcare systems. A comprehensive framework will assess the broader socio-economic and ethical impacts, ensuring that the solutions align with the societal values and healthcare needs. Parterning with leading biomarker companies (GNT, MSInsight, MSICare, MSIPlus and Elypta), we aim to deliver a multi-omic solution for affordable, accessible and effective test to advance the detection of heritable cancer detections in LS. This action is part of the Cancer Mission cluster of projects on “Prevention & early detection (early detection heritable cancers).

Keywords: liquid biopsy microsatellite instability markers metabolomic markers
Grid-Scale Energy Storage: Imperatives for Accelerating the Green Transition (RESTORATIVE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark,Cyprus,Spain,Germany,Italy,United Kingdom,Switzerland,Netherlands,Sweden
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-03-01
End date: 2030-02-28
Duration (months): 48.0
Total project cost (EUR): 5143899.75
EU funding (EUR): 4633854.48
Participants: 16
Project status: SIGNED

Grid-Scale Energy Storage Technologies are the undeniable elements of sustainable energy systems for several reasons such as stabilizing variable energy generation of solar and wind farms, facilitating sector coupling, optimizing resource utilization, improving energy security and resiliency, etc. However, the widespread deployment of such systems is currently very challenging due to major technological, economic, and policy gaps. These issues could only be addressed through cutting-edge research and innovative developments driven by skilled researchers and specialists with multi-lens visions on all critical aspects. Established around a rigorously tailored plan of action, RESTORATIVE brings together the global leaders of relevant fields and industrial actors across Europe to launch a multidisciplinary platform to address the gaps by several breakthrough solutions and training 17 doctoral fellows in different disciplines. To cover the diverse factors influencing the real-world implementation of novel energy systems, the project's thorough work plan is centered around research and PhD training in "mechanical, chemical, and material engineering for technological innovations", "power engineering, and computer sciences for addressing security, reliability, and operation bottlenecks", and "energy economics, energy policy, and environmental sciences for mitigating regulatory, policy and sustainability barriers". Since state-of-the-art research consistently highlights the superiority of thermo-mechanical solutions among all energy storage classes for grid-scale applications, RESTORATIVE is dedicated to Thermo-Mechanical Grid-Scale Energy Storage Systems. Notably, the project has a comprehensive and meticulously planned program of training and career development for doctoral students, including specialized courses, schools, workshops, academic and industrial secondment, entrepreneurship skill-building, etc.

Keywords: thermo mechanical electricity storage high temperature heat storage sustainability analysis reliability cybersecurity energy policy socioeconomic analysis grid integration
Microbial services addressing climate change risks for biodiversity and for agricultural and forestry ecosystems: enabling curiosity-driven research and advancing frontier knowledge (MICROBES-4-CLIMATE)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Services and infrastructures
Action type: Research and Innovation actions
Countries involved: Spain,Belgium,Greece,Italy,France,Germany,United Kingdom,Netherlands,United States,Austria,Portugal,Switzerland,Finland,Bulgaria
Call: Research infrastructure services advancing frontier knowledge (HORIZON-INFRA-2023-SERV-01, 2023)
Start date: 2024-02-01
End date: 2029-01-31
Duration (months): 60.0
Total project cost (EUR): 14494818.44
EU funding (EUR): 14494818.43
Participants: 31
Project status: SIGNED

Terrestrial biodiversity and ecosystems are being challenged by global changes, and threats to agricultural and forestry ecosystems represent some of the most serious environmental and socio-economic menaces that the planet and humanity are facing. Climate change (CG) is widely recognised as one of the most impactful global changes, and since it goes hand-by-hand with biodiversity and services loss in terrestrial ecosystems, they should be tackled together. Microbes constitute the life support system of the biosphere, but they are its most overlooked fraction and are not considered in the context of CG. The overall understanding of the impact of CG on the assembly and functions of microbiomes is still very limited. How the complex microbes-plants-soil interactions and its consequences on plant performance and productivity are impacted by CG is still largely unknown. Additional knowledge also needs to be obtained on the overall ecosystem functioning, and to what extent microbiomes may mitigate stress conditions due to CG. The project MICROBES-4-CLIMATE will provide a wider community of users/researchers, irrespective of location, efficient access to a cluster of complementary world-class Research Infrastructures and their integrated, advanced services along with training and scientific and/or technical support, to address such need. An excellence-driven programme of Transnational Access, which is at the core of the project, will enable users to conduct curiosity-driven research addressing terrestrial biodiversity and ecosystems, in light of the abovementioned multidimensional and still poorly understood microbiomes-plants-soil-environment interactions, and its roles in CG responses, resilience, and mitigation. This will foster the advancement of frontier knowledge and also pave the way to applied research on harnessing plant-microbiome interactions to improve the climate resiliency of plants/crops and to enable e.g., precision, sustainable and resilient agriculture.

Keywords: microbial diversity,terrestrial biodiversity and ecosystems,climate change,microbiomes plants soil environment interactions,resiliency of plants crops,curiosity driven research,
Feasibility of a secretome factory to treat paediatric interstitial lung disease (NICHILD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2023-04-01
End date: 2024-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 2
Project status: CLOSED

Despite their astonishing clinical success on adults, there are still no mesenchymal stem cell (MSC)-based products approved for paediatric use. Preclinical studies support a potential beneficial role of MSC therapy to prevent progression in diseases called childhood interstitial lung disease (ChILD). However, MSCs still suffer from the cost of culturing and storage facilities and a lack of standardization of cell populations, their quality and quantity, donor-related factors, protocols for isolation, in vitro expansion cell delivery and dosing. Our goal is to standardize and automatize the production of MSC secretome and validate it for its translation to paediatric use to treat ChILD. We will explore the feasibility of a “secretome factory” based on (1) isolation of MSCs from donor bone marrow, (2) expansion of MSCs in a micro scaffold called nichoid and (3) long-term culture of MSC for secretome production in an optically monitored bioreactor called MOAB-nichoid. To achieve these goals, in this PoC we will validate the main key performance indicators of the production process and prepare a go-to-market strategy for the secretome biodrug. Our outcomes will be 1) a MOAB-nichoid production line, with total costs compatible with its industrial production and marketing by a pharmaceutical company; 2) standard operating procedures (SOP) for the production process in full compliance with the GMPs in the sector of cell and tissue therapy products (PTC); 3) secretome quality parameters obtained through a comprehensive characterization; and 4) demonstration in vitro of the safety and therapeutic efficacy in the pathologies studied. The outcome of this project will provide a national and international reference point for the industrial production of MSC secretome to treat ChILD and then extending this approach to other pathologies, also affecting adult patients, including chronic intestinal disease and osteoarticular diseases.
Advancing the market uptake of diamond defects quantum sensors (AMADEUS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Innovation actions
Countries involved: France,Germany,Belgium
Call: Quantum sensing technologies for market uptake (IA) (HORIZON-CL4-2021-DIGITAL-EMERGING-02, 2021)
Start date: 2022-10-01
End date: 2026-03-31
Duration (months): 42.0
Total project cost (EUR): 7123760.56
EU funding (EUR): 6016720.63
Participants: 8
Project status: SIGNED

AMADEUS is an industry-oriented consortium that will prepare the market uptake of quantum sensors exploiting NV centres in ultrapure diamond, one of the most promising and market-ready technology of quantum sensing. AMADEUS capitalises on the ongoing ASTERIQS project that develops this technology to TRL 4-5 in the ramp-up phase of the Quantum Flagship. Four advanced applications will be pursued up to TRL 6-7 to answer societal and economical needs where no solution exists yet: • Provide a real-time cartography of the RF signal frequencies in 5G communication cellular networks, and further on future 6G, enabling self-optimizing networks in dense area, thus increasing the number of communications and lowering the energy consumption. • Provide a tool to the semiconductor industry to analyse the defects in microelectronics circuits at room temperature and in standard environment in order to increase the throughput and lower the cost production. • Enable monitoring the muscle and brain activity as novel medical diagnostic tool or as brain-machine interface in the future. • Use monitoring of the magnetic field as a multipurpose tool in harsh environment for space applications or for monitoring of the transient currents in electric car batteries. The consortium involves large companies, RTO’s, SME’s and academic partners. It addresses the whole value chain, from the diamond material to the system working in operational environment, along which the workplan is organised. The partners will produce the material and the components that will be assembled in operational systems and will disseminate the results towards large audiences including end-users. Key actions will be taken to support the transfer to market. In collaboration with major European metrology institutes, AMADEUS will contribute to the standardisation and certification of quantum technology. Consequently, AMADEUS will reinforce the European quantum industry for the benefit of Europe’s economy and citizens.

Keywords: quantum sensing nv centre nitrogen vacancy diamond spin colour centres magnetic field radio frequency
European training network for developing Smart neurOmonitoring solutions to support PRecision medicine in Acute central Nervous Injury (SOPRANI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Belgium,Germany,United States,United Kingdom,Netherlands,Austria
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2023-12-01
End date: 2027-11-30
Duration (months): 48.0
Total project cost (EUR): 2141841.6
EU funding (EUR): 2141841.6
Participants: 9
Project status: SIGNED

In traumatic brain/spinal cord injury and stroke – major causes of death and disability -, progress has come from monitored intensive care and swift action upon detection of secondary insults. Although it is possible to monitor intracranial pressure, the brain & spinal cord still behave as a black box. Current measurable signals only roughly represent ongoing pathophysiological processes, and dynamic insults (eg impaired autoregulation and neurovascular unit dysfunction) cannot be reliably monitored. As a result, no therapeutic action has been shown to be beneficial in randomized patient trials. The project goal is to prepare novel dynamic insult monitoring technologies and to develop improved decision support by integrating disease models and insult/treatment ontologies into smart multimodality monitor software. A parallel goal is to unite high level expertise in clinical, biomedical, statistical and engineering sciences into one network to boost the next generation of researchers to substantially advance the field of neuromonitoring. The network includes 3 relevant animal models and access to large (multi)center patient databases with injury, treatment & outcome data (eg Center-TBI). Direct autoregulation visualization in the cranial window piglet model will be elaborated to improve circulation models and relations with measurable high resolution signals to develop a real-time autoregulation monitor. These metrics will be associated with spreading depolarizations, vasospasm, ischemia and brain function in the rodent stroke models. The models and monitor technology are highly transferrable to patient care. Patient data will be used to build multidimensional statistical disease models. Insult and treatment ontologies will be developed in parallel with insult prediction and insult burden visualization concepts. Smart monitor platforms that aid precision medicine in acute central nervous system injury close to trials and future innovation leaders are expected results.

Keywords: traumatic brain injury,spinal cord injury,stroke,neuro icu,disease model,secondary insult visualization,neurovascular unit dysfunction monitoring,smart neuromonitoring,decision support