Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
RANDOMIZED EVIDENCE OF PSYCHOSOCIAL INTERVENTIONS IN CHILDREN EXPOSED TO TRAUMATIC EVENTS IN LOW AND MIDDLE INCOME COUNTRIES (CHILD TRAUMA IN LMIC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2013-IOF, 2013)
Start date: 2014-06-01
End date: 2018-04-18
Duration (months): 36.0
Total project cost (EUR): 261175.8
EU funding (EUR): 261175.8
Participants: 1
Project status: CLOSED

The applicant is a clinical psychologist whose overall research aim is to link the results of primary research to everyday clinical practice in order to guide mental health care professionals to take evidence-based decisions in promoting human wellbeing. To reach this objective it is necessary to synthesize randomized evidence on the effectiveness of clinical interventions using rigorous standards. The specific research objective of the proposed plan focuses on the effects of psychosocial interventions for children exposed to traumatic events in humanitarian settings in low and middle income countries (HS-LMIC). Literature in this field shows potential effectiveness of such interventions but currently available evidence needs to be strengthened by more rigorous evidence-based evaluation and implementation programs. The proposed research aims to assess the effectiveness of psychosocial interventions for children exposed to traumatic events in HS-LMIC. Additionally, the study will examine whether clinical and socio-demographic characteristics, trauma-related variables, and cultural aspects may act as moderators of treatment effect. Finally, evidence-based profiles on the treatments of this specific population will be developed. In relation to the aforementioned research aims, the educational part of the proposal includes: 1) a specific training in the evaluation of psychosocial interventions for children exposed to traumatic events in HS-LMIC in the Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore; 2) a specific advanced training in evidence-based mental health, research methodology, and epidemiology in the World Health Organization Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Section of Psychiatry, University of Verona, Verona. The expected results have the potential to provide a strong rationale for implementation and large-scale preventive programs worldwide.

Keywords: randomized controlled trial,systematic review,meta-analysis,grade evidence profile,evidence based medicine,child trauma,humanitarian setting,public health,low and middle income countries
Guiding Physical Security by Proofs (GAPS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2013-IEF, 2013)
Start date: 2014-04-01
End date: 2016-03-31
Duration (months): 24.0
Total project cost (EUR): 199317.6
EU funding (EUR): 199317.6
Participants: 1
Project status: CLOSED

Traditionally, cryptography views cryptographic schemes as black-boxes. An adversary may have access to its inputs and outputs, but the internal computation within the box stays secret. Unfortunately, many real-world attacks have illustrated that the black-box model is overly optimistic. So-called side-channel attacks exploit the physical nature of cryptographic implementations and break security by, e.g., measuring the device's power consumption, its running time, or by inducing faults into the computation. This fundamental gap between black-box security analysis and physical reality has inspired a large body of recent work on leakage resilient cryptography. While results on the theory of leakage resilient cryptography certainly show that weakening the black-box assumption is possible, prominent criticism has been raised arguing that security proofs in these models say little about the actual security against relevant side-channel attacks. Hence, they are only of very limited use to guide cryptographic engineers when designing secure cryptographic implementations. Important shortcomings of the current-state-of-the-art range from fundamental issues with the current modeling approach to the fact that proposed schemes are too inefficient or neglect implementation details. The goal of this project is to resolve these shortcomings and develop a sound theory for physical security based on the proof-driven design approach. To take the next step towards a proof-driven design approach for physical security, we will work on three main objectives: (1) Better models and constructions for masking schemes, (2) better designs for leakage resilient symmetric cryptography, and (3) the development of a computer-aided physical security analysis.

Keywords: leakage resilience,provable security,cryptographic engineering
Metal-Free Oxidants in Organic Synthesis (M-FOOS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2013-IEF, 2013)
Start date: 2014-10-01
End date: 2016-09-30
Duration (months): 24.0
Total project cost (EUR): 221606.4
EU funding (EUR): 221606.4
Participants: 1
Project status: CLOSED

Oxidation is one of the central reaction classes in organic chemistry and significant progress has been made in the development of reagents that are capable of oxidising complex molecules with high levels of selectivity. However, much remains to be achieved, and synthetic chemistry is not yet close to the levels of selectivity and efficiency that are achieved by enzymes. The use of small organic molecules to promote chemical reactions is an extremely competitive and timely area in which to work, with an increasing movement from the chemical and pharmaceutical industry towards more sustainable technologies. M-FOOS is a proposal focused on the development of new carbon-based and metal-free oxidising agents to radically change the way that key oxidative transformations are accomplished, making them more powerful and user-friendly. We expect this project to have a significant international impact within organic chemistry in general, including the adoption of our chemistry in academia and the pharmaceutical and chemical industries. The project proposes to develop an approach using o-quinones and iminoquinones as new reagents to accomplish the syn selective (stereospecific) oxidation of alkenes. Collaboration involving synthetic electrochemistry with a world-leading electrochemist, Prof. R. G. Compton (Department of Chemistry at Oxford), will be established to understand and improve the oxidising properties of the o-quinones. Using molecular modelling, in collaboration with an expert (Dr. R. Paton, University of Oxford), we should be able to understand the process and optimise to an excellent candidate for our oxidant system. As 1,2-diamines are present in biologically active natural products, it will also be very fruitful to prepare and then test the biological activity of these diamine containing compounds under an established collaboration with Dr. A. Russell (Pharmacology, University of Oxford).

Keywords: organic chemistry,metal-free oxidising agents,oxidation of alkenes,metal free dihydroxylation,metal free diamination,pharmacology,molecular modelling and theory,electrochemistry.
Dynamic cell coordination in the plant root (ROOTFLOW)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2013-IIF, 2013)
Start date: 2014-08-04
End date: 2015-08-03
Duration (months): 12.0
Total project cost (EUR): 154617.6
EU funding (EUR): 154617.6
Participants: 1
Project status: CLOSED

The fellow proposes to spend a year at the Centre for Plant Integrative Biology (CPIB) at the University of Nottingham, UK, studying the coordination of cellular behavior in the plant root. The coordination is dynamic, poorly understood, and exploited by the root as it responds to environmental stress. The project represents a multi-scale, integrative analysis–relevant throughout biology–that will help improve root traits–essential for tomorrow’s agriculture. The fellow brings to the UK expertise on plant growth and kinematic analysis, expertise that will further the research mission of CPIB as well as be beneficial for European scientists. The fellow’s career will be enriched by immersion in a truly multi-disciplinary environment. Growing roots will be recorded with confocal fluorescence microscopy and image-analysis methods will be developed to quantify growth at a cellular scale. Cellular growth patterns will be characterized as the root responds to its environment (drought). A computer model will be developed to simulate complex dynamics of cellular behavior during root growth and to support mechanistic hypotheses about the underlying causal behavior. This project requires apparatus at CPIB as well as their multi-disciplinary expertise on roots, image analysis, and modeling. The fellow will engage the public through established outreach events run by CPIB. Major deliverables will be software for quantifying growth on a cell-by-cell basis, a model for dynamic cell behavior in the root, and a quantitative understanding of cellular dynamics underlying the root’s response to stress. Software will measure growth at higher resolution than previously and will be widely useful, even for animal biologists. Understanding cellular dynamics underlying the root’s response to stress is important biologically and will help agronomists improve crop varieties to better tolerate stress. The deliverables will support long-term collaboration between the fellow and CPIB.

Keywords: root growth,cell expansion,arabidopsis thaliana,high-resolution imaging,cell-cell interactions
Direct Township Elections in China: Political dynamics and governance outcomes (DIRECTELECTIONSCHINA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2013-IIF, 2013)
Start date: 2015-06-01
End date: 2017-05-31
Duration (months): 24.0
Total project cost (EUR): 309235.2
EU funding (EUR): 309235.2
Participants: 1
Project status: CLOSED

China's direct local elections have received a great deal of international attention, and have been a particular concern of the European Union. But there has been much more focus on understanding village elections than elections at the township level of government. Direct township elections are significant, however, because – unlike village elections – they involve the lowest tier of the Chinese governmental system. And they were suspended in 2006 after only eight years of experimentation. In this project we aim to understand first why township elections were permitted and then suspended, and second, their governance outcomes. The project will contribute to understanding the obstacles to bottom-up democratization in China, as well as the impacts of elections on local governance. We will conduct intensive interviews with 30 officials in central party-state institutions as well as Chinese and foreign officials responsible for establishing and implementing cooperative programmes or projects on direct local elections. We will also adopt an empirical case study approach to understanding the governance effects of direct elections, comparing five townships that have introduced elections with five townships that have not. This method will deliver new cross sectional data for analysis. The researcher, Professor Dong Lisheng (Chinese Academy of Social Sciences), has been closely involved in monitoring local elections in China and has unparalleled access to decision makers and local governments there. Together with a team of political scientists at the University of Glasgow with expertise in Chinese politics and in elections and electoral politics, he will be able to produce the definitive analysis of China's township level reform experience, assess the way forward for Chinese local elections and advise European policy makers and researchers on ways of fostering good governance and democratization in China.

Keywords: china,local elections,democratization,governance,survey
Optimal non-demolition quantum measurements (ONDEQUAM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2013-IEF, 2013)
Start date: 2014-04-01
End date: 2016-03-31
Duration (months): 24.0
Total project cost (EUR): 194046.6
EU funding (EUR): 194046.6
Participants: 1
Project status: CLOSED

The goal of the project is the development and implementation of novel, highly efficient techniques for the quantum non-demolition measurement of photon number states. Cavity-QED experiments using Rydberg atoms to probe microwave fields stored in ultra-high finesse resonators have witnessed enormous progress in the past decades. Optimization of the information extraction rate will enable us to study new types of states which so far have been experimentally inaccessible due to their fast decoherence rates. The scope of the emerging experimental prospects ranges from the stabilization of mesoscopic photon states to the preparation of non-local NOON - states. A thorough understanding of the decoherence dynamics of complex, mesoscopic states is of fundamental interest in quantum physics, while controlling the environment-induced decay is an important prerequisite for virtually all possible future technological implementations of quantum devices. The project goals will be achieved by employing two different advanced QND methods, which will consume significantly fewer resources in terms of probe atoms and measurement time. The first method is based on the real-time evaluation of all information available from preceding QND detections in order to optimize the phase setting of the Ramsey interferometer that is used to perform the QND measurement. In a second step we will further enhance the efficiency of the measurement by simultaneously utilizing different velocity classes to also tune the atom-photon interaction itself. This promises to eventually permit data extraction rates close to the optimum given by information theory. Both methods will initially be evaluated with a single cavity, and then adapted to a dual-cavity setup, which will allow us to operate also with non-local states.

Keywords: cavity quantum electrodynamics,quantum non-demolition measurement
Knowledge Transfer of In vivo surgery and cardiovascular phenotyping for angiogenesis and preeclampsia studies (IVSCP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2013-IIF, 2013)
Start date: 2014-05-01
End date: 2016-04-30
Duration (months): 24.0
Total project cost (EUR): 309235.2
EU funding (EUR): 309235.2
Participants: 1
Project status: CLOSED

The major aim of this IVSCP project is the knowledge transfer from the Marie Curie International Incoming Fellow (IIF), Dr. Murdoch with strong expertise in cardiovascular microsurgery and background in effectively phenotyping cardiovascular disease in transgenic mouse models to the EU host organisation – Vascular Biology at Aston University. The area of medical research is geared around the knowledge that pivotal in the development of preeclampsia are changes in anti-angiogenic soluble Flt-1 (sFlt-1) and angiogenic placenta growth factor (PlGF). Therefore to find an answer to the current unmet medical need a better understanding of their regulation in preeclampsia and angiogenesis is required. The research aims will drive the knowledge transfer, these include to (i) Assess glutaredoxin-1 as a therapeutic target of preeclampsia; (ii) identify whether Heme oxgenase 1 and cystathionine-g-lyase regulate sFlt-1 by changes in glutaredoxin-1 to effect in vivo angiogenesis; and (iii) Increase our understanding of PIGF gene regulation and function in the endothelium. Dr. Murdoch will aid knowledge transfer through IVSCP by (i) establishing a new research collaboration with his current institute, Vascular Biology Section, Boston University; (ii) provide in vivo training of angiogenesis models and understanding of redox signalling to PhD students and Post-Doctoral Fellows in the host institute and co-host institutes (University of Birmingham and Exeter); (iii) identify novel redox sensitive targets involved in preeclampsia; (iv) provide lectures/practical to undergraduate and MSc students in the School of Life Science; and (v) organise workshops/forums for the wider ERA. Overall, the proposal intends to impart valuable skills and launch an international collaboration. In addition, this will accelerate scientific output from the Vascular Research team which recently moved to Aston University, to maintain its world-leading reputation in preeclampsia.

Keywords: oxidative stress,preeclampsia,angiogenesis,cardiovascular,sflt-1,hmox-1,cth,glutaredoxin-1,ischemia,genetically modified mice
Study of Structure-Property-Process relations in real functional FOODs (FOODSPPROCESS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2013-IEF, 2013)
Start date: 2014-03-01
End date: 2016-02-29
Duration (months): 24.0
Total project cost (EUR): 187414.8
EU funding (EUR): 187414.8
Participants: 1
Project status: CLOSED

In the context of current economic and social changes, the research in the agri-food area should aim, among other things, to the optimization of products and processes. The improvement of the food products must be directed towards ensuring the nutritional and specific functional benefit. Regarding the improvement of processes, they should ensure the quality and safety of environmentally friendly food products produced optimizing the use of resources. A research activity focused on fundamental analysis of the structure-property-process and aimed at innovation and technological improvement of the processes so that the results can be used directly by the agri-food companies will help to achieve these challenges. This project raises the technological improvement of some functional food manufacturing processes by in-depth analysis of the interactions between certain bioactive components, food ingredients with technological functionality and food matrices with cell structure. It will also determine the effect of some changes in the process conditions.

Keywords: structure-property-process,functional food,mandarin juice,apple,high homogenization pressures,vacuum impregnation,hot air drying,probiotic microorganism
Archaeology of the European Medieval Earthquakes (AD 1000 - 1550) (ARMEDEA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2013-IEF, 2013)
Start date: 2014-04-07
End date: 2016-04-06
Duration (months): 24.0
Total project cost (EUR): 221606.4
EU funding (EUR): 221606.4
Participants: 1
Project status: CLOSED

Historical seismic catalogues such as SHARE (Seismic Hazard Harmonization in Europe) and AHEAD (European Archive of Historical Earthquakes Data 1000-1899) play a significant role in hazard mitigation across the European Union. These EU-funded projects are based mainly on documentary surveys but the archaeological verification for seismic activity remains under-researched. The aim of ArMedEa is to develop the analysis of the physical impacts of earthquakes, tsunamis and landslide seismic-induced events during the later Middle Ages (defined here as 1000-1550 AD). This will be achieved at a European scale, adopting a specifically archaeological approach to collate and integrate information from a wide range of sources including standing buildings, buried stratigraphical sequences and palaeoenvironmental data. This differs from current perspectives which tend to be driven largely from an earth science perspective. The main objectives of the project are: (a) the development of a geographical database for seismic events in the Middle Ages drawing on existing catalogues and untapped ‘grey literature’; (b) the investigation of a sample of well-documented episodes using a combination of remote sensing and fieldwork, and; (c) to understand the ‘risk-sensitive tactics’ adopted by medieval societies in different regions, such as their resilience and hazard reduction strategies. The project will create online outputs such as an archaeoseismic database and the first historic risk map for the Middle Ages, as well as summary reports evaluating case-studies, mitigation strategies and the economic and cultural effects of earthquakes in different cultural contexts. This innovative research will be developed at the Department of Archaeology and the IHRR (Institute of Hazard, Risk and Resilience) at the University of Durham, establishing a wide-ranging of national and international collaborations and a strong network of research contacts for the applicant.

Keywords: medieval archaeology,medieval europe,earthquakes,tsunamis,landslides,gis,remote sensing,architecture,risk,natural hazards