Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A WORLDWIDE E-INFRASTRUCTURE FOR COMPUTATIONAL NEUROSCIENTISTS (outGRID) (OUTGRID)

Framework: FP7 — Capacities
Programme: Research Infrastructures
Destination: Support to policy development and Programme implementation
Action type: Coordination and support actions
Countries involved: Italy,France,France,Canada,United States,United Kingdom
Call:  (FP7-INFRASTRUCTURES-2009-1, 2009)
Start date: 2009-11-01
End date: 2012-07-31
Duration (months): 33.0
Total project cost (EUR): 491677.0
EU funding (EUR): 439982.0
Participants: 6
Project status: CLOSED

FP7 neuGRID (www.neuGRID.eu) is being developed aiming to provide large sets of brain images paired with grid-based computationally intensive algorithms for studies of neurodegenerative diseases. Two infrastructures with similar aims are operational or under construction overseas. In Canada, the Montreal Neurological Institute (MNI) aims to develop a pan-Canadian platform (CBRAIN http://cbrain.mcgill.ca) for exchange and distributed processing of 3D/4D brain imaging data. In the US, the LONI – Laboratory of Neuro Imaging at UCLA (http://www.LONI.ucla.edu) already provides a number of algorithm pipelines to perform a wide range of brain image analyses that come with an intelligent and interactive distributed visual programming environment. These three complementary neuroscience initiatives could converge to one unique worldwide facility, given the following enablers: (i) the databasing software of neuGRID is the same as CBRAIN’s, (ii) an ultra broad band connection links Europe to Canada (GTRN), and (iii) both platforms are under construction, thus providing latitude for channelling towards interoperability. Interoperability of neuGRID with LONI is facilitated by (i) the database structure of neuGRID being the same of LONI, i.e. that of the North American Alzheimer’s Disease Neuroimaging Initiative (ADNI), (ii) an ultra broad band connection links Europe to US (GTRN) and (iii) neuGRID may adopt LONI’s workflow authoring system for algorithm pipelining. outGRID will organize workshops in Europe, Canada, and the US to promote the exchange of technical information, direct the development of the infrastructures towards interoperability, and develop specific international calls and call topics for research and development activities aimed at achieving full interoperability. outGRID will be a first step toward a global scientific grid infrastructure, it will trigger convergence within the neuroscientific community and, in the long run, the biomedical research community.

Keywords: e-infrastructures,computational neuroscience,grid computing,egee glite,geant,soa
Mouse Model of CoQ deficiency: pathogenesis and treatment (COQMITMEL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2009-11-01
End date: 2013-10-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Coenzyme Q10 (CoQ10) deficiency is an autosomal recesive disorder where the encephalomyopathy and nephropathy seems to be the most important clinical presentations. Some patients respond to CoQ10 supplementation but others do not. In my Postdoctoral stay in Columbia University I identified the first mutation in PDSS2, which encoded the protein responsible for the syntesis of decaprenyl chain. Moreover, I have studied the pathological consequences associated to CoQ10 deficiency in culture fibroblasts with mutations in PDSS2, COQ2, ADCK3 and COQ9. The results show that mitochondrial bioenergetic, the increase of oxidative stress and the defect in de novo pathway for pyrimidines can be the main pathological mechanisms associated to CoQ10 deficiency. However, the tissue specificity need to be investigated since CoQ10 is present in all cells types and is critical for mitochondrial function. In addition, potential treatment need to be tested. Then, I propose: 1) Generate COQ9 knockin mice. Dra. Rahman’s Group has recently found a mutation in this gene in a patient with CoQ10 deficiency. This gene encode Coq9, an enzyme involved in ubiquinone biosynthesis. However, the function of this enzyme is still unkown and I will study it; 2) Charaterize COQ9 knockin mice including behevioural, clinical, hitological-morphological, physiological, bioquemical and genetical studies; 3) Develop and apply different therapeutical strategies: a) Early an late onset treatment with CoQ10; and b) antioxidant strategy (melatonin administration). The results will be essential to undertand and treat the pathegenesis of CoQ10 deficiency, as well as other primary mitochondrial disorders. Likewise, the results can be important in the treatment of neurodegenerative diseases or aging, since CoQ10 supplementation is been used in clinical trials of parkinson´s patients or it is recommended as nutritional suplemmentation in the elderly population.

Keywords: laboratory animal science,bioenergetics,medical genetics,functional biology,mitochondria,coenzyme q10,coq10 deficiency,mitochondrial diseases,melatonin
Sustainable e-Infrastructures across Europe and India (EU-INDIAGRID2)

Framework: FP7 — Capacities
Programme: Research Infrastructures
Destination: Support to policy development and Programme implementation
Action type: Coordination and support actions
Countries involved: Italy,United Kingdom,France,United Kingdom,France,India
Call:  (FP7-INFRASTRUCTURES-2009-1, 2009)
Start date: 2010-01-01
End date: 2011-12-31
Duration (months): 24.0
Total project cost (EUR): 1225958.0
EU funding (EUR): 740000.0
Participants: 15
Project status: CLOSED

EU-IndiaGrid2, capitalising on the achievements of the FP6 EU-IndiaGrid (EUIG1) project and huge developments in India on infrastructure and leveraging the expertise and experience obtained by its partners during EUIG1, will continue the momentum, attained in e-Infrastructures evolution in Europe and India, to create and ensure sustainable collaboration in many new areas of science, education and technology across the two regions. EU-IndiaGrid2 main objectives are to: O1) consolidate &amp; enhance cooperation between European and Indian e-Infrastructures for the benefit of EU-Indian collaboration in e-Science EU-IndiaGrid2 will make full use of the EUIG1 project achievements and of the strong cooperation links established with the foremost European and Indian e-Infrastructure initiatives paving the way for successful sustainable cooperation across European and Indian e-Infrastructures. O2) support a set of new grid applications in areas strategic for EU-Indian collaboration EU-IndiaGrid2 will support a set of applications in the domain of Climate Change, High energy Physics, Biology, Material Science which are considered strategic for EU-Indian collaboration in the ICT domain. O3) ensure a sustainable approach to e-Infrastructures across Europe and India through dissemination actions, meetings &amp; workshops EU-IndiaGrid2 will continue supporting the Roadmap for Sustainability outlined by the EUIG1 project relying on the progress towards objectives O1 and O2 and on targeted dissemination actions, meetings and events O4) foster and enhance cooperation with other European Initiatives in the Asian region and worldwide EU-IndiaGrid2 will continue the strong cooperation links established by EUIG1 with the most relevant projects and institutions e.g. EGEE/EGI, GEANT and the major Indian e-Infrastructure Initiatives as GARUDA NGI and NKN. It will also cooperate with regional projects like EELA2, EuAsiaGrid, SEEGRID and, if approved the EUMEDSupport and EUChinaGrid2 proj

Keywords: grid,e-infrastructures
Design and real time energy sourcing decisions in buildings (ENERGY WARDEN)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: ICT for mobility, environmental sustainability and energy efficiency
Action type: Collaborative project
Countries involved: Spain,Poland,United Kingdom,Italy,Spain,Serbia,Cyprus,Greece
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2010-01-01
End date: 2013-06-30
Duration (months): 42.0
Total project cost (EUR): 3992205.0
EU funding (EUR): 2741485.0
Participants: 10
Project status: CLOSED

ENERGY WARDEN (EW) addresses the optimisation of renewable energy technology (RET) deployment in the building domain. EW will develop and market the following products: SIMULATOR (EW-S): A simulator and modelling tool, including dynamic models for energy producing, storing and using units that may provide decision aid when designing or retrofitting energy infrastructures at the building domain. Important to highlight is that the simulator will be run in a short and a long term time frame; that of 1-4 days and that of a year. The first time-frame will be driven by meteorological forecast data, which have a large level of confidence for this time-frame. The first time frame delivers set points to the EW Controller, whereas the more long term one is more suitable for assessing RET investment scenaria. CONTROLLER (EW-C): The controller will be based on an expert system/ neural network approach and will provide real time control of the RET infrastructure. The real time controller will manage how energy is allocated between uses, stores, and possibilities to be fed back to the energy network. The EW-C may also unveil energy use trends, particularly useful for the simulator. In this way, the EW-S and the EW-C form a closed loop. The EW-C will include a data collection module, low cost hardware including sensors and data loggers/ transmitters, which will be deployed at the building over a period of time and facilitate the collection of data. It is emphasized that emerging wireless protocols will be a key aspect of this data collection, as such systems are particularly important in the case of energy retrofit action, where wired sensors may be impossible or costly to install. POLICY (EW-P): A higher level functionality will support policy conformance and emission trading, allowing to monitor the building performance, old and new, against existing policies or standards, including the EU directive on building energy as well as supporting the capability for use in emission trading calculations. EW will be an open, standard compliant, system, able to support many new, upcoming, supply/ store/ use options that are constantly entering the market.

Keywords: energy sourcing,simulation and modeling,real time control,policy support,wireless data collection networks
New Paradigm in the Design of Degradable Polymeric Materials - Macroscopic Performance Translated to all Levels of Order (PARADIGM)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Products and process engineering
Countries involved: Sweden
Call:  (ERC-2009-AdG, 2009)
Start date: 2010-03-01
End date: 2016-02-29
Duration (months): 72.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

A new generation of polymeric materials is needed promptly that does not behave like traditional commodity plastics in terms of environmental interaction, degradation pattern, fragmentation tendency, and biological persistency. I herein propose a new paradigm in the design of polymeric materials; the design of polymeric materials through a retro-structural approach where the macroscopic performance is translated to every scale level of structural order so that appropriate molecular recognitions are identified and subsequently synthetically generated in a bottom-up procedure. Inspiration on how to design such materials is best drawn from Nature which is unsurpassed in its ability to combine molecular building blocks into perfectly designed versatile super- and supramolecular structures with well-defined properties, disassembly patterns, and biological functions. A closer look into the structural build-up of biological materials gives important clues on how to design synthetic functional materials with desirable environmental interaction. In addition to advanced synthesis, surface modification and processing, the materials and their degradation behavior will be thoroughly characterized by using traditional characterization techniques in combination with latest spectroscopic and imaging techniques. I have chosen to focus on two areas that stand out as highly prioritized in maintaining or even raising our quality of life; sustainable materials for commodity applications and tissue engineering systems in biomaterials science. This is a bold high risk proposal which if successful will have a ground-breaking influence on how we design polymeric materials.

Keywords: sustainable polymeric materials,tissue engineering,degradable,macromolecular intra- and inter-actions
Complex Research of Earthquake’s Prediction Possibilities, Seismicity and Climate Change Correlations (BLACKSEAHAZNET)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Bulgaria,Greece,Slovenia,North Macedonia,Türkiye
Call:  (FP7-PEOPLE-2009-IRSES, 2009)
Start date: 2011-01-01
End date: 2013-12-31
Duration (months): 36.0
Total project cost (EUR): 475200.0
EU funding (EUR): 475200.0
Participants: 9
Project status: CLOSED

The purpose of project BlackSeaHazNet is development of long-term research cooperation through coordinated joint program of researcher’s exchange. The base is Complex Program for research of possibility for forecast earthquake’s time, place (epicenter, depth), magnitude and intensity using reliable precursors. Precursors research includes regional geophysical and seismological monitoring, monitoring of water sources and their Radon, Helium, Mercury concentrations, crust temperature, monitoring of electromagnetic field under, on, and above Earth surface, meteorological monitoring, including earthquake clouds and electrical charge distributions, near space monitoring, aimed to estimate Earth, Sun and space (cosmic rays) origins of variations, and biological precursors. For many variables well working monitoring exists (for example INTERMAGNET geomagnetic field monitoring). For others (for example: monitoring of Earth currents distribution) monitoring have to be created. Due to complex real time variables monitoring the parallel output of the Program can be different time scale estimations for other natural hazards and risk assessment, as well as the correlations between human behavior and electromagnetic and other geophysical variables variations. Proposed regional network can be considered as first step for creating wide interdisciplinary scientific consortia for formulation of more adequate models of today Climate change, Earth seismic processes as well as different time scales regional earthquakes forecasts. Which will the bases for future EC framework , regional and bilateral Projects. The scientific and practical results will be considered in workshops and regional training seminars.

Keywords: earthquakes,seismology,tectonics,geodesy,hydrogeology,disaster preparedness (geophysics),natural hazards (geophysics),risk assessment (geophysics),climate change
New Methods in Non Archimedean Geometry (NMNAG)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Mathematical foundations
Countries involved: France
Call:  (ERC-2009-AdG, 2009)
Start date: 2010-03-01
End date: 2015-02-28
Duration (months): 60.0
Total project cost (EUR): 1541800.0
EU funding (EUR): 1541800.0
Participants: 1
Project status: CLOSED

During the last decade, spectacular achievments have been completed in Algebraic and Arithmetic Geometry and in Representation Theory by using powerful new tools provided by Motivic Integration and Berkovich spaces. We propose to develop a general framework for geometry over non archimedean valued field that will provide common foundations for Motivic Integration and Berkovich spaces. This will allow to broaden the range of potential applications. A main originality of our approach is the use of advanced tools from modern Model Theory, like definability and stable domination, together with methods from Algebraic Geometry. The relevance of Model Theory to non archimedean geometry may be illustrated as follows: geometry over valued fields ultimately combine geometry over the residue field and geometry over the value group. Model theorically these geometries correspond respectively to stable and o-minimal theories. These are of a very different nature and Model Theory provides unifying concepts allowing to treat them on equal footing. This approach will in particular allow us to solve several fundamental open questions on the tame nature of the topology of Berkovich spaces and should open new perspectives towards outstanding conjectures like the Monodromy conjecture. Our goal is also to use model theoretic tools in order to give new applications of Motivic Integration to Algebraic Geometry and Singularity Theory.

Keywords: model theory,singularities,arithmetic geometry,motivic integration,valued fields,berkovich spaces.
Low-x Gluon Distribution from the Discretised BFKL Equation. (LOWXGLUE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany
Call:  (FP7-PEOPLE-2009-IRSES, 2009)
Start date: 2011-01-01
End date: 2012-12-31
Duration (months): 24.0
Total project cost (EUR): 16200.0
EU funding (EUR): 16200.0
Participants: 2
Project status: CLOSED

The BFKL equation in perturbative QCD, with certain well-defined additional assumptions about the non-perturbative (infrared) contributions to the QCD pomeron, will be used to extract a realistic gluon distribution at low-x. This will be exploited to make predictions for jet cross-sections at the LHC. The second part of the project involves the extension of the BFKL equation to non-forward pomerons. These will be used to extract generalized gluon distributions which will, in turn, be used to make predictions about diffractive events at LHC.

Keywords: physical sciences,low-x,gluon,lhc,diffraction,structure,pomeron
Hybrid CMOS/Magnetic components and systems for energy efficient, non-volatile, reprogrammable integrated electronics (HYMAGINE)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Systems and communication engineering
Countries involved: France
Call:  (ERC-2009-AdG, 2009)
Start date: 2010-07-01
End date: 2015-06-30
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Spinelectronics merges magnetism and electronics (Nobel Prize 2007). Besides its fundamental interest, it has found applications in hard disk drives (1998) and in non-volatile standalone memories (MRAM, on market since 2006). MRAMs integrate CMOS components with magnetic tunnel junctions (MTJ). The PI and his team are convinced that besides MRAMs, this hybrid CMOS/MTJ technology can yield a totally new approach in the way electronic devices are designed. Most CMOS devices such as microprocessors are based on Von Neumann architecture in which logic and memories are separate components. The unique set of characteristics combined within MTJs: cyclability, switching speed, scalability, makes it possible to conceive novel electronic systems in which logic and memory are intimately combined in non-volatile logic components (non-volatile CPU). Such systems would have outstanding advantages in terms of energy savings, logic-memory communication speed, ultrafast reprogrammability, compactness, design simplicity. The objective of this project is to lay the fundation of this novel approach, which requires addressing both fundamental and more applied issues. The basic issues concern the improvement and reliability of spintronic materials, mastering the speed and coherence of magnetization switching, developing tools for the quantitative interpretation of MTJ properties and for designing hybrid CMOS/MTJ devices. The applied goals are the conception, building and testing of a few illustrative devices demonstrating the outstanding advantages of this technology. A further one is to establish an internationally recognized roadmap for this non-volatile logic. If successful, its impact on European microelectronics and magnetism industry could be huge.

Keywords: magnetic tunnel junctions,spin-transfer,content addressable memory,rf oscillator,fpga
MACROSCOPIC LAWS AND DYNAMICAL SYSTEMS (MALADY)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Mathematical foundations
Countries involved: Italy,France
Call:  (ERC-2009-AdG, 2009)
Start date: 2010-04-01
End date: 2015-07-31
Duration (months): 64.0
Total project cost (EUR): 1372720.0
EU funding (EUR): 1372720.0
Participants: 2
Project status: CLOSED

Physics provides descriptions of the world at many different scales, yet the relations between such descriptions are poorly understood. In particular, since Boltzmann and Einstein, we interpret the world we see as the product of the microscopic dynamics of a large number of atoms. In spite of this, no satisfactory rigorous derivation of a macroscopic equation (e.g. the heat equation) from such a microscopic physical model exists. This sorry state of affairs is extremely unsatisfactory both from the theoretical point of view and for applications. Indeed, as the technology is entering the mesoscopic scale (nanotechnology), the need for a rigorous understanding of how the phenomenological macroscopic laws emerge and of their limits of validity becomes paramount. We believe that recent advances in the theory of Dynamical Systems and Probability, to which the members of our team have contributed, allow key progresses in the understanding of the above problem. The ultimate goal of this proposal is the derivation of macroscopic evolution laws from a microscopic Hamiltonian evolution. To this end we will consider a series of intermediate models: a) inspired to an anharmonic chain with some noise (of a fixed strength and not itself responsible for the changes in the local energy); b) inspired to hard spheres interacting via elastic collisions and confined by fixed periodic obstacles (gas of geometrically constrained hard spheres). The above project entails the solution of major problems in the fields of Dynamical Systems and Probability. In addition, it would contribute to substantiate Boltzmann&apos;s theoretical picture by providing a conclusive rigorous example of non-equilibrium macroscopic behavior arising from an (interacting) microscopic mechanical model.

Keywords: smooth ergodic theory,hydrodynamic limit