Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
CO2 ROUTES ACROSS EUROPE (COREU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Norway,Greece,Poland,Ukraine,Cyprus,Slovenia,France,Germany,Italy,Belgium,Switzerland,United Kingdom,Czechia
Call: Development of CO2 transport and storage demo projects (HORIZON-CL5-2023-D3-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 35696960.0
EU funding (EUR): 29285939.38
Participants: 44
Project status: SIGNED

COREu will demonstrate key enabling technologies in a CCS value chain and support the development of three new CCS routes in Central-East Europe (CEE), helping accelerate CCS development . COREu will (a) provide the means for development of an open-access, trans-national network (infrastructure and logistic) to connect emitters with storage sites in Europe, by identifying multimodal transport requirements, and developing emitters’ clusters to create the demand and the investment rationale, (b) increase the knowledge of the CCS value chain across Europe through interconnected initiatives, sharing of experience, knowledge and data to create a common framework that encompasses all key aspects of CCS deployment: technological know-how, business models, consensus management, monitoring, reporting and validation, policy framework, transport and storage safety. COREU will contribute to 6.8Mt/year in CO2 reduction by 2035 and 36Mt/year by 2050, develop 8 innovations for Measurement Monitoring Verification, interoperability and Value Chain Monitoring, and improve the Internal Rate of Return of CO2 infrastructure investment by 6% through de-risking core technologies.

Keywords: demonstrations,ccs value chain,co2 impurities,multi modal transportation
Isolating the first ARCtic GIant viRUSes and their bioactive compounds (ARCGIRUS) (ARCGIRUS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-01-13
End date: 2027-01-12
Duration (months): 24.0
Total project cost (EUR): 210911.04
EU funding (EUR): 210911.04
Participants: 1
Project status: SIGNED

Giant viruses (GVs) comprise a ubiquitous and unique viral group. Their large genomes encode a majority of proteins with unknown functions, an important but overlooked source for new biotechnological breakthroughs. Most known GVs have been isolated in hosts from the genus Acanthamoeba and none has yet been found from the Arctic, one of the most important ecosystems in the world. This came as a surprise considering various metagenomic studies revealed the presence of GVs worldwide, especially in marine ecosystems. More studies on host-GVs interaction also bring forth their potential for viral-derived bioactive compounds. Hence, this project (ARCGIRUS) aims to innovate in giant virus research by (O1) isolating the first algal-infecting giant virus from the Arctic. This will overcome the Acanthamoeba-focused host bias and at the same time explore an important but never studied environment in this field. Then, I will (O2) characterize the isolates, and (O3) develop a novel method using mass spectrometry to find potential bioproducts at the phenotypic level from cells infected with giant viruses. The biological data obtained through this project will have an impact on virology and evolutionary biology, likely leading to interesting basic research projects and applied science advances, in addition to increased awareness of the Arctic virosphere, and nature in general. The GVs isolates and publications generated through this project will become important references in the field and open the possibility of collaboration. The use of social media and collaboration with museums will advertise the study of GVs and raise awareness of their role in the marine microbiome to general audiences. Overall, the novelty of finding giant viruses infecting microalgae from the Arctic, together with the training and knowledge acquired from this fellowship, will support my career goal of becoming a leading polar microbiologist specializing in giant viruses.

Keywords: giant virus,arctic,microalgae,virus isolation and characterization,viral derived bioproduct,bioprospection,mass spectrometry
Ancient Spaces of Healing: Integrated Perspectives for the Study of Urukean Medicine (1st millennium BCE) (ASHIPUM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

The overarching goal of the project ASHIPUM is to understand how ancient Mesopotamian healers acted within their spatial, geographical and social contexts. To do this, I will conduct a practice-oriented study - still lacking in Assyriological scholarship - of the archives of the exorcists-healers from Late-Babylonian Uruk (end 5th century-beginning 2nd century BCE), integrating textual and archaeological data. This case study has not been comprehensively analysed from a medico-historical viewpoint. By focusing on its promising features, I will be able to overcome three problems related to the study of Mesopotamian medicine. ASHIPUM’s objectives are: 1) to determine what the exorcists-healers of Late-Babylonian Uruk knew, on the basis of their archives; 2) to integrate textual information with archaeological and material data relevant for a medico-historical study; 3) to reconstruct the daily practices and the know-how implied by healing-related activities in Uruk. As designed, the project will be best implemented at Paris 1 University Panthéon-Sorbonne under the supervision of Philippe Clancier in the light of his expertise in the archives of the exorcists-healers and their historical, material contextualisation. I will benefit from my integration into his team ArScAn-HAROC, specialized in material culture, and the trainings offered by my host institution in archaeology, anthropology, French language, digital skills, project management and career development. In turn, I will share my experience on Mesopotamian medicine and give impulse to this subject at ArScAn by networking with specialists across the region of Paris and beyond. The action includes dissemination activities through presentations, journal articles, a conference (with related proceedings) and online content for ArScAn’s projects. Communication will be ensured by online presence, participation at outreach events in the Parisian region, a citizen science program and a poster exhibition.

Keywords: ancient near east,mesopotamia,mesopotamian medicine,materiality of medicine,material culture,history of medicine,history of ancient medicine
Ball-Milling Mechanochemistry at the Molecular Level-2 (BM3L-2)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany,Austria
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2024-05-01
End date: 2029-04-30
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 2
Project status: SIGNED

Ball milling mechanochemistry is receiving tremendous attention over the last years. The applicant has pioneered the use of it for effecting catalytic reactions, culminating in catalytic ammonia synthesis from H2 and N2 at room temperature and atmospheric pressure. In spite of the success in driving reactions mechanically, the molecular level understanding of the key processes under mechanical activation is still in its infancy. The proposed program will change this, using methods giving insight at the atomic scale. By a multi-pronged approach, the applicant – partly in collaborations - will experimentally probe at the atomic scale hypotheses, which have been put forward to explain the special effects of mechanochemical reactions, to provide key elements for a conceptual understanding. Three topical areas will be covered, in addition, one general purpose tool for the study of mechanochemical reactions will be developed. (1) Temperature dependent luminescence will be used to monitor temperatures during model impacts in order to probe the hot spot and magma/plasma hypotheses. (2) The role of hypothetical, short-lived, mechanically induced defects in catalysis will be analyzed locally at the atomic scale in scanning probe microscopes. (3) In order to understand mechanically induced phase transitions, mechanical forces will be applied in-situ to precursor crystals in a transmission electron microscope (TEM), and phase transitions, for instance from boehmite to corundum, will be followed at the atomic scale by TEM imaging. (4) As a general tool to study the influence of mechanical forces, a hammer/anvil system will be developed in which directly after applying mechanical force the system can be studied by various analytical methods. Overall, the program is expected to provide deep mechanistic understanding of different aspects of mechanochemistry to advance it to a next level.

Keywords: mechanochemistry,mechanocatalysis,in situ analysis
INvestigating Transmission and Early Replication of Rift valley fever viruS following mosquito Exposure in Cutaneous Tissue (INTERSECT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 217076.16
EU funding (EUR): 217076.16
Participants: 1
Project status: SIGNED

Vector-borne viruses (arboviruses) pose an increasing global threat, causing widespread disease in both humans and animals with significant health and economic impacts. In Europe, the mosquito-borne Rift Valley Fever Virus (RVFV) is especially concerning as this virus is expanding its territory beyond Africa, causing severe disease in both humans and ruminants. Despite ongoing research, critical gaps remain in understanding the RVFV infection cycle, particularly regarding the initial mechanism of mosquito mediated transmission. Supported by the Marie Skłodowska-Curie Actions program, the INTERSECT project will expand knowledge on early RVFV infection in the skin using advanced virus particle analysis and 3D imaging techniques. These insights are crucial for developing targeted therapeutics and improve risk models. The INTERSECT project aims to investigate early RVFV infection in the skin of its natural host, focusing on mosquito transmission and replication. The specific objectives are to 1) map the genomic composition and distribution of RVFV virions, 2) examine the initial infection in ruminant skin, and 3) elucidate the early host immune response. To address its aims, the project will analyze RVFV infected mosquitos, skin biopsies and sera from infected lambs to study RVFV transmission, replication dynamics, and host immune responses. The project will employ cutting-edge methodologies, including tissue optical clearing, fluorescence in situ hybridization (FISH), advanced microscopy, and spatial transcriptomics to uncover critical insights into early RVFV infection mechanisms. The project will provide advanced training in imaging and genomic analysis and enhance transferable skills through publications, presentations, and public engagement. INTERSECT will advance the scientific understanding of RVFV infection and develop methods applicable to other arboviruses, ultimately contributing to global health, informing vaccine development and outbreak prevention.

Keywords: rift valley fever virus,arbovirus cutaneous transmission,tissue optical clearance
Where are the Humanities in the Medical Humanities? How Comics Can Improve Healthcare Training, Practice, and Dissemination (HumInMedHum)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-01-01
End date: 2029-08-31
Duration (months): 68.0
Total project cost (EUR): 1984844.0
EU funding (EUR): 1979844.0
Participants: 1
Project status: SIGNED

The last decade has seen a steady increase in the number of medical schools offering courses in the Medical Humanities, an interdisciplinary field that promotes the study of the Humanities in healthcare education as engendering greater awareness in practitioners in training and thereby better healthcare practice and dissemination. While research in the field is rapidly developing, it problematically remains largely theoretical, based on a single case study, and/or presents Humanities scholarship as merely additive to rather than integrated in education. It is therefore crucial to comprehensively examine how the Medical Humanities works—and can work—in and through practice. This project will critically elaborate the benefits of further integrating the Humanities in the Medical Humanities by examining and expanding the discourse on Graphic Medicine. A flourishing field attentive to the study and production of comics about health and healthcare, Graphic Medicine utilizes theoretical and artistic research practice in productive reciprocal exchange. As such, it is well suited to evaluate and develop the aims, current applications, and potential of the Medical Humanities to positively affect not only healthcare scholars and practitioners, but also comics artists, patients, their families, carers, and the public. Through cross-national, cross-cultural, and cross-linguistic analyses of Graphic Medicine, from healthcare education to online information, and from individual artistic practices to collaborations between comics artists and healthcare institutions, this project’s five work packages will offer unprecedented comparisons and unprecedented reach to multiple stakeholders who can use the project’s findings for future research. In an era of global pandemic and rampant disinformation, the importance of improving healthcare training, keeping the public informed about healthcare, and creating new healthcare knowledge from the perspective of patients cannot be undervalued.

Keywords: graphic medicine,comics studies,critical medical and health humanities,artistic research practice
Researchers and citizens: facing together the European challenges (MADRIDNIGHT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Spain
Call: European Researchers' Night 2022-2023 (HORIZON-MSCA-2022-CITIZENS-01, 2022)
Start date: 2022-05-01
End date: 2024-04-30
Duration (months): 24.0
Total project cost (EUR): 300000.0
EU funding (EUR): 300000.0
Participants: 14
Project status: CLOSED

The European Researchers' Night in Madrid will bring together researchers to the general public and will increase awareness of the importance and benefits of research and innovation, creating an understanding of the impact of researchers' work on citizen's daily life, and raising young people’s interest in science and research careers. The project will achieve these objectives by means of festive activities to be carried out in the Region of Madrid in the morning and evening of the last Friday and Saturday of September 2022-2023. Pre events and post events will be also organized. The Madrid Night project also includes Researchers at Schools activities throughout the year. In these activities, researchers will be visiting schools, allowing teachers and pupils to engage with them on important topics faced by our societies, such as those included in the missions in Horizon Europe: cancer, adaptation to climate change, healthy oceans, seas coastal and inland waters, climate-neutral and smart cities and soil health and food. Students and teachers will also visit the researchers’ workplaces. The MADRIDNIGHT activities will be addressed to public at large, science-addicts and science-reluctant, children, families, teachers, elderly, people regardless their scientific background with a special focus on families, pupils, and students, with the main purpose of encouraging STEM subjects and science careers, university students and also vocational education and training students. Different activities will be offered focused on the missions in Horizon Europe. The project will involve researchers, benefited by EU funds, especially the MSCA. The activities will point out the transnational and diversity aspects of research, showing the attractiveness of their jobs that can be done everywhere in Europe. Universities, research centres, museums, hospitals, NGOs, foundations and Industry (Spin offs, SME or Large Companies) in the Region of Madrid will be at the core of the project.

Keywords: researchers,outreach,society,schools,scientific carrers,innovative promotion,missions,cancer,climate change,oceans,seas coastal,inland waters,smart cities,soil health and food
Understanding the Science and Identifying the Issues Behind the Low Performance of Z Scheme Photocatalysts for CO2 Reduction (PZschemeCO2Red)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 203464.32
EU funding (EUR): 203464.32
Participants: 1
Project status: CLOSED

CO2 emission is a serious problem that threatens life on earth via global warming and climate change. Artificial photosynthesis is a green strategy to tackle water-energy-carbon challenges simultaneously. Z-scheme charge transfer mechanism is thought of as one of the promising approaches for photocatalyst design, to eventually commercialize CO2 reduction. However, the photocatalytic CO2 reduction using the current Z-scheme photocatalyst systems did not show the expected performance. The main objectives of this project are using advanced in situ/operando characterization to understand the science and identify the issues behind the low performance of current Z scheme photocatalysts and the development of innovative patterned thin film Z scheme photocatalysts that can address these issues. The synergy of Z scheme charge transfer and frustrated Lewis pair sites will be also investigated by constructing novel BiVO4/Cs2CuBr4 and WO3/Cs2CuBr4 heterostructures containing state-of-art photocatalyst material (lead-free halide perovskite). The proposed research is an interdisciplinary proposal combining Chemistry, Physics, Materials Science, Chemical Engineering, and Environmental Science. It includes both training of the candidate and knowledge transfer to the host institution. The candidate’s experience in the field, the specialized supervisor, and the appropriate environment at UU along with the well-identified objectives and the achievable methodology ensure reaching the research and training objectives. Eventually, the project will strengthen the academic track record of the candidate and give him the opportunity to accomplish his main carrier goal and being a university professor and researcher of international repute in any of prestigious institutions across the globe to disseminate knowledge and to serve mankind by building future generations of researchers.

Keywords: z scheme,photocatalysts,co2 reduction,in situ operando characterization,lead free halide perovskites
Clinical Validation of In Vivo Imaging for Detecting Immune Dynamics (VIVID)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands,Spain,Germany
Call: Transition Open 2024 (HORIZON-EIC-2024-TRANSITION-01, 2024)
Start date: 2025-07-01
End date: 2028-06-30
Duration (months): 36.0
Total project cost (EUR): 2661574.21
EU funding (EUR): 2443726.0
Participants: 4
Project status: SIGNED

VIVID is a project on the Clinical Validation of In Vivo Imaging for Detecting Immune Dynamics. Optimising cancer treatment is a challenge, especially with combination therapies and patient variability. The ability to study cell migration in a quantitative and non-invasive manner in vivo, of endogenous cancer-fighting immune cells and administered therapeutic cells is essential for biomarker-driven and personalised clinical trials. Our imaging agent, BEACONs, allow for multimodal, quantitative imaging of cell populations; here with quantitative 19F MRI and fluorescence. This project will demonstrate and validate the feasibility of cell tracking using multimodal imaging and increase the maturity of BEACONs (to TRL 5-6) through a first-in-man clinical trial in current cancer standard of care. Our specific objectives are to 1) Set up a clinical trial of interest to large pharma, here the imaging of labelled immune cells in a neoadjuvant setting; 2) Build a business plan and create a spin-off; 3) Ensure that any new IP is protected; 4) Perform outreach towards patients and end-users. The potential societal impact of using BEACONs includes being able to assess and adapt complex therapies in major diseases such as cancer organ transplants, allowing a more targeted treatment and reducing patient burden such as negative side effects of ineffective treatment. The economic benefit of using BEACONs is large, while also reducing animal use, and enabling early assessment of cell therapies and cancer therapies. VIVID allows the application of our technology in a new field -that of personalisation of cancer therapy- aside from cell therapies, increasing our potential customer base (oncology drug market expected $285B in 2023).

Keywords: imaging agent non invasive cell tracking 19f mri quantitative fluorescence endoscopy cell monitoring imaging product package