Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Integration of Bio-Conversion and Separation Technology for the production and application of platform chemicals from 2nd generation biomass (BIOCONSEPT)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Life sciences, biotechnology and biochemistry for sustainable non-food products and processes
Action type: Collaborative project
Countries involved: Netherlands,Belgium,Germany,Finland,Germany,Spain,Italy,France,Germany,Austria,United Kingdom,United Kingdom,Germany,Netherlands,Belgium,Belgium,Netherlands,Israel,Germany,Slovakia,Spain,Netherlands,Czechia,Netherlands,Switzerland,Germany
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 12984576.8
EU funding (EUR): 8888371.0
Participants: 37
Project status: CLOSED

BioConSepT aims to demonstrate the technically feasibility of White Biotech processes for the conversion of 2nd generation biomass into platform chemicals, which are 30% cheaper and 30% more sustainable than existing chemical routes or 1st generation processes. BioConSepT uses lignocellulose and non-edible oils & fats as cheap, abundantly available feedstocks, which cannot be used as food. The main achievements expected for BioConSepT are: (1) to develop the robust enzymes and micro-organisms suited for the more dirty 2nd generation feedstocks; (2) to reduce equipment costs and the number of process steps by the integration of bioconversion and highly selective separation technologies; (3) to facilitate easy integration in existing production chains by deploying combinations of bio- and chemical conversions and by proving the suitability of the produced platform chemicals for bio-based polymers, resins, plasticizers, solvents and surfactants and (4) by realisation of the 1st demonstration of integrated production chains from 2nd generation feedstocks to platform chemicals at industrially relevant scale. BioConSepT will bring novel technologies from lab to pilot scale by high level applied research. The consortium consists of 15 SMEs (suppliers of equipment, bioconversions, separation technologies and services), 10 large industrial parties (producers, end-users, engineering and consultancy companies) and 5 leading RTOs from 11 different countries. The large industrial parties and SMEs expect new products, processes, services and customers with a potential value of hundreds of M€. BioConSepT will reduce the total processing costs and thus improve the competitiveness of the European agro/food and chemical industries. The use of renewable biomass will lead to a significant reduction of Green House Gas emissions and a more secure supply of feedstocks, energy and water as well as reduction of waste generation.

Keywords: white biotechology,platform chemicals,bioconversions,in-situ product recovery,demonstration
Development of active, intelligent and sustainable food PACKaging using PolybutyleneSUCCInate (SUCCIPACK)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Fork to farm: Food (including seafood), health and well being
Action type: Collaborative project
Countries involved: France,France,Czechia,Italy,Spain,Belgium,Greece,France,France,France,Belgium,Italy,Spain
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2012-01-01
End date: 2014-12-31
Duration (months): 36.0
Total project cost (EUR): 4037593.39
EU funding (EUR): 2999521.0
Participants: 19
Project status: CLOSED

SUCCIPACK aims to support European industry efforts to introduce biobased polybutylene succinate (PBS) as a new material on the food packaging market. Its main advantage is that it has complementary properties compared to other biobased polymers like polylactic acid. PBS is synthesized by polycondensation of succinic acid and butanediol, both identified as key “building blocks” from renewable resources which will be produced on a large scale in the coming years. The aim of SUCCIPACK is to develop sustainable, active, and intelligent food packaging materials based on green PBS that can be flexibly used by packaging and food industries. A first aspect is the optimization of the synthesis and compounding of polymer and copolymer grades for industrial plastic transformation processes to obtain films, trays and pouches. Tailored packaging functionalities will be obtained by flexible in-line surface treatments to control gas barrier properties and to introduce antimicrobial activity. The performance and safety of the novel packaging materials will be assessed for selected food products, representative of different food categories and preservation technologies. Special efforts will be put to explore PBS recycling routes, including chemical recycling by monomerization. An original intelligent labeling function will be added to monitor material degradation and recondensation, during shelf life and recycling. Life cycle assessment (LCA) and life cycle cost analysis (LCC) will be applied to guide the material development and to assess the sustainability of the whole packaging concept. SUCCIPACK will help European industry, especially SMEs, to strengthen their competitive advantage over the currently fast growing green PBS developments in the US and Asia. The cooperation between 7 research organizations, 1 large industrial player and 10 SMEs will facilitate an effective uptake of the results by the food and packaging industry.

Keywords: polybutylene succinate,pbs,lca
Development of Cytochrome P450 Enzymes for the Chemical Manufacturing Industries (P4FIFTY)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,Germany,Netherlands,France,Denmark,Denmark,Germany,Switzerland,Sweden
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 4165298.77
EU funding (EUR): 4165298.77
Participants: 10
Project status: CLOSED

The objective of the P4FIFTY project is to deliver a trans-European network of industrially oriented white biotechnologists fully trained in the application of cytochrome P450 monooxygenases (P450s) for application in the chemical manufacturing and pharmaceutical industries. This will involve academic groups investigating P450 diversity exploration from the wild type enzymes and their genes, genome mining for novel P450s, the expression of these in suitable hosts, the enzymology and molecular biological manipulation of these (including directed evolution and high throughput screening [HTS] methods), the chemical application and finally the chemical and biochemical engineering aspects of application. These inputs are supported by two industrial partners one from the pharmaceutical industries (drug metabolism and synthesis) and one from the large scale chemical manufacturing industry.

Keywords: cytochrome p450 enzymes,white biotechnology,chiral synthesis,chemical manufacture,drug metabolites,biohydroxylation,molecular biology,enzymology
Pollen thermotolerance and crop fertility (SPOT-ITN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Netherlands,Israel,Netherlands,Austria,Italy,Italy
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2015-12-31
Duration (months): 48.0
Total project cost (EUR): 2827562.02
EU funding (EUR): 2827562.02
Participants: 9
Project status: CLOSED

The Marie Curie Initial Training Network SPOT-ITN will establish a multi-site network of early stage and experienced researchers at 9 partner institutions - including 3 from the private sector - in 4 European member countries and Israel to investigate fundamental and applied aspects of thermotolerance mechanisms contributing to the protection of pollen development at increased ambient temperatures. The envisioned joint research program is of broad commercial interest and will be an important contribution to the efforts undertaken world-wide to ensure future stability of food production in view of the prognosticated global climate change. Although the initial focus will be on tomato as an important agricultural crop, the results are expected to become applicable to other cultivated plants in the long run. Based on individual research projects of the young researchers, the main focus of the network will be to perform common, multidisciplinary experiments on a broad variety of heat-sensitive and heat-tolerant tomato genotypes and mutant lines at the molecular, cellular and organismic level with two major objectives: i) to describe the molecular basis of the striking sensitivity of pollen development at higher temperatures and regulation of pollen-specific heat stress response and thermotolerance mechanisms; and ii) to develop BIOMARKERS of POLLEN THERMOTOLERANCE usable in future screening programs to improve breeding of new heat-tolerant cultivars. Besides training of specific research tasks, the multi-disciplinary research program includes advanced methods and high-throughput technologies in plant genetics, molecular and cell biology, physiology, and bioinformatics. In addition, a multitude of opportunities are provided for training complementary skills to broaden the knowledge of the young researchers for developing their future career with comprehensive possibilities in a wide field of research areas in Life Sciences in both, the public and the private sector.

Keywords: pollen development,pollen thermotolerance,solanaceae,tomato,crop fertility,heat stress,heat stress transcription factors,heat stress response,climate change,biomarkers
IMPROVING FOOD SECURITY BY REDUCING POST HARVEST LOSSES IN THE FISHERIES SECTOR (SECUREFISH)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Fork to farm: Food (including seafood), health and well being
Action type: Collaborative project
Countries involved: United Kingdom,Netherlands,Kenya,Ghana,Namibia,India,Malaysia,Argentina,Portugal,Netherlands
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2012-01-01
End date: 2014-12-31
Duration (months): 36.0
Total project cost (EUR): 3965592.0
EU funding (EUR): 2997422.0
Participants: 14
Project status: CLOSED

Food security is a major concern for all countries in the face of population increase and diminishing energy and water supplies. Over one billion people in low and middle income countries suffer from malnutrition. To meet the UN Millennium Development Goals to eradicate hunger and poverty, it is essential to reduce post harvest losses, including in the fisheries sector. The overall objectives of SECUREFISH are to strengthen capacity in low cost technology; to improve the preservation of existing fish supplies; to utilise waste and bycatch to produce value-added products; to develop an integrated quality management tool and finally to test the developed technology and quality management tool in different real third country conditions. There are six work packages (WP). WP1 will ensure the efficient management of the project. WP2 will develop low cost innovative processing tools based on traditional technology for preserving fish including a solar tunnel drier, a modified solar assisted extruder and fast freezing/ continuous atmosphere freeze-drier (CAFD). In WP3, underutilised bycatch and waste by-products of fish processing will be recovered and converted to high value products. WP4 will develop an effective total quality management tool (safety and risk assessment; HACCP quality cost and traceability, nutritional and eating quality and carbon footprint) of three fish product chains (solar dried, extruded and frozen/CAFD) which will be tailored to suit local needs. The technological advances (WP2) and quality management tool (WP4) will be evaluated in the three fish product chain case studies in Africa (Kenya, Namibia, Ghana), Asia (India and Malaysia) and Latin America (Argentina) to include different economic, cultural and social conditions. The case studies involve stakeholders including SMEs to ensure sustained implementation of project results. WP6 details a strategy for education, training and dissemination to widely promote the results and guidelines.

Keywords: post harvest losses,fish,food security,nutritional quality,consumer safety,processing,novel producrs,functional products,quality control
Training and Research AImed at Novel Antibacterial Solutions in Animals and People (TRAIN-ASAP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark,France,Spain,United Kingdom,Netherlands,Italy,Belgium
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-01-01
End date: 2016-09-30
Duration (months): 57.0
Total project cost (EUR): 3515586.69
EU funding (EUR): 3515586.69
Participants: 9
Project status: CLOSED

TRAIN-ASAP addresses a very urgent public health issue. The lack of effective antibacterial drugs against resistant bacteria poses a serious threat to human health and has huge economical consequences to the healthcare system. The objective of this ITN is to fill the current gap between the burden of infections due to resistant bacteria and the strong need for alternative solutions to combat antibiotic resistance in both humans and animals. Young researchers will be trained in the scientific and complementary skills needed to implement a broad range of antibacterial approaches including discovery of new antibiotics, synthesis of antimicrobial peptides with improved pharmacological properties, improvement of the clinical efficacy of currently known drugs, and alternative strategies based on phages and bacteriocin-producing organisms. TRAIN-ASAP is a multidisciplinary and intersectorial ITN dedicated to the scientific and professional training of 14 early-stage researchers, including 2 financed by the University of Copenhagen, with the aim to develop novel antibacterial solutions for humans and animals. The consortium includes 7 academic institutions, 9 private enterprises and 2 national research centres representing 9 countries. The training programme is characterized by a unique innovative and multidisciplinary approach based on the use of front line research tools in molecular biology, combinatorial chemistry and in vivo pharmacology, an appropriate balance between scientific and generic skills training, and a strong contribution by the private partners in the form of mentoring, courses and secondments. Considering the urgent need for new drugs to combat antibiotic resistance and the growing demand for skilled scientists specialised in antibacterial drug discovery, TRAIN-ASAP is expected to have a strong impact on the careers of the trainees and result in a lasting collaboration between the partners and political, societal and economical benefits to Europe.

Keywords: antibacterial drugs,drug discovery and development,infectious disease,antibiotic resistance,human health,animal health,animal production,health sciences
TRAINING NETWORK IN INNOVATIVE POLYELECTROLYTES FOR ENERGY AND ENVIRONMENT (RENAISSANCE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,France,Germany,Sweden,Belgium,Spain,Italy,Belgium
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2012-05-01
End date: 2016-04-30
Duration (months): 48.0
Total project cost (EUR): 3102433.01
EU funding (EUR): 3102433.01
Participants: 10
Project status: CLOSED

The introduction of new ionic moieties (cations and anions) into polymers is giving rise to a new family of functional polymers with particular properties and new applications which is provoking a RENAISSANCE of the chemistry and applications of classic polyelectrolytes. However, further developments and a better understanding of the properties and applications of innovative polyelectrolytes are still necessary to develop their actual and emerging applications. RENAISANCE will aim at excellence in developing high quality training opportunities through a synergistic collaborative research programme between industry and academia in the field of polymer science as applied to needs in Energy&Environment areas. RENAISSANCE ITN allows the assembly of a truly world class multidisciplinary and intersectoral research and training network, capable to locate Europe at the forefront of emerging polyelectrolyte research. The six academic partners of the network (POLYMAT, LCPO, MPI CI, BIORGEL, ULg and IMDEA) and the four industrial participants (KITOZYME, PG B, PG I and REPSOL) are internationally renowned for their research and training activities in the fields of competence that they represent. RENAISSANCE training program includes local training activities such as individual research projects, PhDs, master courses, supervision and mentoring, specific local courses, as well as network-wide activities such as secondments, local courses open to the network participants, four workshops,one summer schools and one conference. Both scientific training and complementary skills training will be taken into account. The network will offer training to 11 Early Stage Researchers a 1 Experienced Researchers. The ultimate goal will be to train ESRs as quality researchers, prepare them for positions in industry and academia suitable to become future leader scientists in the multidisciplinary emerging field of innovative polyelectrolytes

Keywords: polymer chemistry,macromolecular chemistry,industrial chemistry,chemical engineering,polymer technology,electrochemical storage,environmental technology
An interactive protein engineering portal with validated software and database facilities (NEWPROT)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Life sciences, biotechnology and biochemistry for sustainable non-food products and processes
Action type: Collaborative project
Countries involved: Netherlands,Germany,United Kingdom,Germany,Czechia,Austria,Italy
Call:  (FP7-KBBE-2011-5, 2011)
Start date: 2011-12-01
End date: 2015-11-30
Duration (months): 48.0
Total project cost (EUR): 2983800.0
EU funding (EUR): 2258800.0
Participants: 10
Project status: CLOSED

Two academic groups and eight SMEs who all work on different aspects of protein engineering will collaborate and produce a website that will consist of a portal with an embedded workbench to provide users a self-service system for in silico protein engineering. This interactive self-service portal will give users access to a wide variety of protein engineering facilities and information systems, and will allow them to interactively work with a comprehensive set of well-documented, well-integrated computational protein engineering tools. The databases that will be provided will be curated, and the software and protocols will be validated by performing a variety of protein engineering experiments on a series of enzyme classes. The portal and the interactive workbench will be freely available, and they will be solidly based in modern information technology. The usability for protein engineering will be thoroughly experimentally validated.

Keywords: protein engineering portal,interactive protein engineering software,experimental validation of predictive power of software
Novel nanoparticles for drug delivery to the skin (NANODRUG)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,France,France,Austria,Portugal,Belgium,Germany
Call:  (FP7-PEOPLE-2011-ITN, 2011)
Start date: 2011-11-01
End date: 2015-10-31
Duration (months): 48.0
Total project cost (EUR): 3752752.62
EU funding (EUR): 3752752.62
Participants: 8
Project status: CLOSED

The aim of the NANODRUG Network is to contribute to the defragmentation of the emerging field of nanomedicine by providing a unique training programme that will cover all different aspects ranging from NP synthesis and characterisation, drug delivery, molecular biology to nanotoxicology, preclinical studies, risk assessment and nanotechnology policy making. The NANODRUG training program is far superior to any training that individual partners can provide and will equip researchers with innovative and creative skills and enhance their career prospects in the public and private sectors. The scientific aim of this research training network is to develop and characterise a selected set of novel intelligent nanomaterials and to study their suitability as novel drug delivery systems targeting inflammatory skin diseases. The development and use of the NP described in this project aims to overcome the current difficulties that limit the applications of NP to skin drug delivery. The unique physico-chemical properties of these novel NP such as ultra small size, large surface to mass ratio, high reactivity and the capability to tailor them to applications will ensure that when complexed with drugs the pharmacokinetics and therapeutic index of the delivery systems can be significantly improved compared to the free molecules and the capability to pass the SC of the skin greatly enhanced. This project brings together 6 academic groups and 2 industrial teams as full partners, complemented by 3 associate partners, one of which is an industrial team, distributed over a total of 6 EU member states and 1 non-ICPC country. The consortium brings together groups with a very interdisciplinary expertise ranging from polymer synthesis and characterisation, computational modelling and physicochemical characterisation of materials to bioavailability, NP formulation, drug distribution and nanotoxicity, genetics, drug delivery and clinical dermatology.

Keywords: polymer chemistry,nanotechnology,dermatology,computational chemistry,analytical chemistry