Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Business INN Moldova (Business INN Moldova)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Moldova, Republic of
Call: H2020 2D CONSULTATION EEN (H2020-EEN-SGA2-2017-2018, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 14225.0
EU funding (EUR): 14225.0
Participants: 5
Project status: CLOSED

H2020

Keywords: innovation management,improve,republic of moldova,sme instrument
Integrated Crossbar of Microelectromechanical Selectors and Non-Volatile Memory Devices for Neuromorphic Computing (SelectX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Romania
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-04-01
End date: 2018-03-31
Duration (months): 24.0
Total project cost (EUR): 125422.8
EU funding (EUR): 125422.8
Participants: 1
Project status: CLOSED

Building artificial neuronal networks (ANN) that mimic their biological prototypes is one of the remaining grand challenges in computing. Despite transistor scaling and improved architectures, modern supercomputers require kWs of power to replicate functionality for which living neural networks take only a few Ws. Currently there is no hardware that can provide a high synaptic density with reasonable energy consumption. Hybrid CMOS chips with stacked crossbars of analog non-volatile memory devices (NVM), like memristors, promise to deliver the required high density and connectivity. However, the crossbar architecture suffers from the sneak path problem, neighbouring devices creating electrical shorts around the selected device. Biological systems do not have this problem due to the inherent nonlinearity of their potentiation and spiking. A high nonlinearity can be reproduced in a crossbar by using a selector for each memory device. The selector commonly used is a transistor which limits the scalability and stackability. This project proposes an alternative selector based on a two-terminal MEMS switch. MEMS switches are heavily researched for RF applications, but their high nonlinearity makes them attractive as selectors for NVM. This project will design, simulate and fabricate a crossbar of integrated MEMS selectors and TiO2 memristor devices. Initially, the selectors and memristors will be optimized separately, then monolithically integrated. Their scalability and stackability will be investigated. Finally, a prototype 3x3 crossbar of integrated memristor/MEMS selectors will be fabricated and used to demonstrate vector matrix multiplication - a foundational element of many complex ANNs like a perceptron. The proposed work is not linked to a particular NVM (ReRAM is an example), being suitable for any dense crossbar system that requires selectors. The findings are relevant to the fields of hardware ANNs and non-volatile memories and to major industry players.

Keywords: memristor,mems switch,crossbar,non volatile memories,hardware implementation of neural networks
Data Should Inspire – Development of a Disruptive Big Data Analysing Solution for Marketing Agencies (DASHIN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Malta
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-11-01
End date: 2017-02-28
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

InboundMuse™ is a revolutionary tool that automates the entire process from data mining to insight generation and furthermore suggesting the optimal solution just as a human would – something unique in the realm of digital marketing. This would save hours from an analyst’s job. When this powerful tool is introduced in an agency setting with multiple clients, its effects are cumulative and the agency ends up saving days off its schedule, which means faster delivery, better client satisfaction and client retention. Client retention is the crucial factor for an agency because its 10x more expensive to sell to a new client then to an existent client. Through SME Instrument Phase 1, we are seeking finance to prepare a Feasibility Study and Business Plan to determine in-depth the possibility, feasibility, risk, viability, profitability and sustainability of this new project.

Keywords: business strategies,business support services,marketing,disruptive,artificial intelligence
Epigenetics and System Biology of Stem cells and Reprogramming (EpiSyStem)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy,Germany,Israel,Belgium,France,Netherlands,Netherlands
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-03-01
End date: 2022-08-31
Duration (months): 54.0
Total project cost (EUR): 3598191.72
EU funding (EUR): 3598191.7199999997
Participants: 8
Project status: CLOSED

Chromatin is the basic regulatory unit of life, and as such it controls developmental and functional states of all cells, including pluripotency. In recent years methods to study chromatin and transcription have dramatically improved and expanded to genome-wide global approaches on the one hand, and single cell biology on the other, allowing systems-level understanding of epigenetic regulation of stem cells, reprogramming and development. The Epigenetics and Systems Biology of Stem Cells and Reprogramming Network (EpiSyStem) is comprised of 8 world renowned, ERC-granted researchers, 2 professional leading industrial partners and supported by 3 partner organizations and 3 international world acclaimed scientists as an advisory board, to provide a unique training environment. EpiSyStem combines chromatin biology in stem cells, early embryos and reprogramming, including the modelling of human neurological, chromatin-related diseases with bioinformatics, epigenetics/epigenomics, and systems biology at the population and single cell / single embryo level. This multidisciplinary approach will enable profound training and deep, systems-level understanding of chromatin biology and epigenetic regulation of stem cells, differentiation and reprogramming, with a strong support by industrial partners. The objectives of EpiSyStem is to create a European mesh in which 14 outstanding PhD students will be trained in fundamental questions of biological research, be exposed to the latest technologies and breakthroughs, supervised by leading experts with international contacts - with the aim to facilitate their path to future leadership with holistic view, coupled with the forefront of the current epigenetic research in the field. They will enjoy exchange programs, workshops on emerging topics in stem cell epigenetics and bioinformatics, international conferences and meetings, and will communicate their findings to the scientific community as well as the general public.

Keywords: epigenetics,chromatin,nucleosome,pluripotency,methylation,histone,embryonic stem cells,ips cells,bioinformatics
EUROpean clinical validation of a new ex vivo eXpanded stem cell theraPy for cArdiac regeNeration after acute myocarDial infarction: EUROXPAND (EuroXpand)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: France
Call: Supporting innovative SMEs in the healthcare biotechnology sector (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2018-05-01
End date: 2023-12-31
Duration (months): 68.0
Total project cost (EUR): 5000000.0
EU funding (EUR): 5000000.0
Participants: 1
Project status: SIGNED

Heart failure (HF) after acute myocardial infarction (AMI) remains the first cause of death in developed countries, above cancer, with a life expectancy less than 5 years. With an overall cost of 83 billion euros per year worldwide , HF represents a global public-health issue. Treatments following AMI are still characterised by burdensome surgical procedures and post-operative treatments which both fail to prevent HF development. In this context, CellProthera, founded in 2008, developed an innovative technology based on the discoveries of its founder, Pr. Hénon, who has worked on stem cells for more than 35 years. Unlike its competitors, CellProthera has already demonstrated the efficacy and the safety of its cell therapy, thanks to a successful Proof of Concept study. The clinical outcomes indicated an excellent safety profile associated with an outstanding long-term recovery of the cardiac function, facilitating socio-professional reinsertion. The process used during the pilot phase could not be patented nor industrialised, limiting its availability to all patients. Hence, Cellprothera has developed a patented cell expansion automate StemXpand®, combined with StemPack® Kit creating an innovative business model, and a new cell therapy process less invasive, more affordable, and decreasing health costs related to HF in the order of 50 to 75%. With the efficacy demonstration of the new process through EuroXpand project, Cellprothera’s cell therapy could become the reference treatment to prevent HF after AMI. This way, CellProthera will be in possession of all the assets required to achieve a leader position in HF prevention, after AMI. Indeed, with a potential of millions patients / year worldwide, Cellprothera’s total turnover is expected to reach 2,7 billion euros in 2030, associated to the creation of at least 70 direct jobs by 2027 and several thousands of indirect jobs, particularly in Cell Therapy Centres.

Keywords: secondary heart failure,acute myocardial infarction,cardiac regeneration
Real-time diagnostics for Enabling Advanced laser-based roll to roll materials Processing (REAP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-07-01
End date: 2017-06-30
Duration (months): 24.0
Total project cost (EUR): 187866.0
EU funding (EUR): 187866.0
Participants: 1
Project status: CLOSED

An experienced researcher with laboratory expertise in real time monitoring of laser-matter-ambient-interactions will be diversified towards scalable production which is desperately needed to fully realise the potential of high repetition rate, multi-kiloWatt, femtosecond and picoseconds laser technologies. The fabrication of integrated multifunctional thin film devices by additive (inkjet, spray) and subtractive (laser) manufacturing on Roll to Roll (R2R) production platforms is also suddenly possible and desperately needed to transform the competitiveness of Europe’s SME manufacturing sector. The training programme will lead to scalable innovation by developing diagnostics for ultra-precision laser processes. The initial objective of the project is to identify which intersecting value chains for real time or in-line diagnostics can fully realise the potential of short pulse laser structuring. Three diagnostics based on gated (i) spectral analysis of laser generated plasma plumes, (ii) image analysis of laser material ambient interactions and (iii) laser induced breakdown spectroscopy will be developed. The Fellow will demonstrate two process diagnostics using the R2R pilot line at the industry site. The application of these on-line tools will create pathways for cost effective production based on new nano-inspired materials relevant to flexible large area electronics. The multi-partner training environment provides excellent facilities for the talented ambitious Fellow. Over 30+ researchers will be directly impacted by the project. An active programme of knowledge transfer and information dissemination is also proposed based on industrial workshop, active conference participation, journal publications, and science promotion.

Keywords: laser,camera,spectral emission,shadowgraphy,laser breakdown spectroscopy,roll to roll,thin flexible glass,large area electronics,process monitoring
How to regenerate the mammalian kidney (REGMAMKID)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Spain
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-11-01
End date: 2020-10-31
Duration (months): 60.0
Total project cost (EUR): 1499604.0
EU funding (EUR): 1499604.0
Participants: 1
Project status: CLOSED

Kidney non-endocrine functions are primarily performed by millions of individual integral units called nephrons. Although the adults of simple vertebrates (fish, amphibians and reptiles) have the ability to regenerate entire nephrons by a process called “nephron neogenesis”, this capacity is absent in birds and mammals. In this regard we have observed, for the first time, that the murine neonatal kidney is able to generate new nephrons after the resection of the 20 per cent of the kidney mass. In the same manner, our recent published data on the generation of human kidney organoids ex vivo from kidney disease derived induced pluripotent stem cells (iPS), demonstrates the suitability of iPS technology to establish an unprecedented platform for drug screening, disease modelling and kidney regeneration. Thus, with support from REGMAMKID we will carry out a dual strategy for kidney regeneration and therapy. For kidney regeneration, we will make use of our newly developed mouse model of neonatal kidney regeneration and identify the molecular and epigenetic drivers responsible for this process. For kidney therapy, we will generate specific kidney cell populations with therapeutic potential such as podocytes and tubular epithelial cells by combining emerging cutting-edge technologies from the fields of cellular reprogramming and pluripotent stem cells differentiation. Making use of the tools developed in REGMAMKID we will model two different genetic kidney disorders: one affecting the podocyte (Congenital Nephrotic Syndrome) and other leading to an excessive proliferation of tubular epithelial cells (Autosomal Dominant Polycistic Disease). These studies will significantly impact on our understanding of kidney disease and healing.

Keywords: kidney,regeneration,induced pluripotent stem cells,gene editing,disease modeling
QUANTUM OPTICAL MAGNETOMETER FOR MEDICAL APPLICATIONS (QUMAG)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-03-01
End date: 2017-08-31
Duration (months): 18.0
Total project cost (EUR): 149921.0
EU funding (EUR): 149921.0
Participants: 1
Project status: CLOSED

Sensitive detection of weak magnetic fields produced by human nerves, eyes and brain has a large potential as a diagnostic tool for bio- and medical applications. However, measurements of magnetic fields have not yet been developed into a ubiquitous tool for medical diagnostics, one of the reasons being that commercially available magnetometers with high enough sensitivity are based on expensive superconducting magnetometers (SQUIDs) which require cryogenic cooling. Within the INTERFACE project we have developed a novel optical magnetometer with sensitivity rivaling SQUIDs but operating at room or human body temperature. This breakthrough has been achieved by the design based on optimizing quantum noise of the light-atoms interaction. First results on detection of action potential magnetic signals from a nerve provide an example of quantum technology in service of real world applications. Within the QUMAG project we shall explore the potential of the quantum magnetometer in ophthalmology. In collaboration with medical researchers and leading ophthalmologists we shall develop a magnetoretinograph for eye diagnostics. The small fiber-connected chip which can be placed in the close proximity to the eye and provide noninvasive, inexpensive, ultrasensitive diagnostics will find a market in curing such diseases as glaucoma, retinitis pigmentosa, and inborn blindness.

Keywords: optical magnetometry,biomagnetism,quantum technology,magnetoretinography,vapor cell
A shared mobility On-Demand Service (SHOTL)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Spain
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-12-01
End date: 2017-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

SHOTL (www.shotl.com) is an on-demand collective transport service that re-defines the daily commute. Comprising a fleet of minivans and intelligent routing software, SHOTL will enable millions of people living and working in ‘first-mile’ and ‘last-mile’ areas to reach their daily destinations, offering a convenient and affordable alternative to private cars. Every day around 60M Europeans commute to work by car, spending 68 B€ annually. This is the primary cause of road congestion, responsible for lost productive time, wasted fuel, air pollution, increased cost of doing business and considerable losses in GDP. SHOTL will empower existing public transportation networks by delivering: novel routing technology that offers a truly user-centric travel experience, easy-to-use mobile Apps for commuters and drivers and integration with public transit networks for seamless, end-to-end travel. Our solution is truly unique in the market. Other on-demand mobility services carry only 1-2 people per trip, apply ‘surge pricing’ during peak times and do not effectively reduce congestion. SHOTL will be the only solution that effectively combines collective transport, a first-rate user experience and affordability, eliminating 165K cars from urban roads, saving 300K hours of productive time and avoiding nearly 40K tonnes of CO2 emissions annually across Europe by 2022. We have completed Alpha tests in a real city environment in Barcelona providing initial validation of our innovation’s technical performance, and our participation in the StartUp4Cities program has demonstrated SHOTL’s market potential. In Phase 1, we will carry out a feasibility study in order to demonstrate SHOTL Alpha to key stakeholders, improve the product based on real user needs, strengthen our IP protection strategy, define our commercialisation strategy and create a detailed business plan that will ensure rapid expansion into key European markets, eventually extending to North America and beyond.

Keywords: ride sharing,smart mobility,data science,machine learning,big data,intelligent transport system,smart city
SELF-BOUYANT PRECAST CONCRETE FOUNDATION FOR THE CRANELESS INSTALLATION OF COMPLETE OFFSHORE WIND TURBINES: FULL SCALE OFFSHORE PROTOTYPE (ELISA)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-2-2014, 2014)
Start date: 2015-06-01
End date: 2017-05-31
Duration (months): 24.0
Total project cost (EUR): 3575441.46
EU funding (EUR): 2497862.5
Participants: 1
Project status: CLOSED

The offshore wind market is a young and rapidly growing market, whose current project pipeline for 2025/30 would equal nearly 80 nuclear plants, mostly in Europe. The next decade and beyond may average 1,000 offshore towers/year worldwide, with an overall investment volume around 15-20.000 M€/year. This growing sector faces technological challenges, as it is set to move into deeper waters further offshore while being able to reduce the costs in order to reach a competitive LCOE (levelised cost of energy). For water depths above 40m (70% of the future market) approximately 40-50% of investment corresponds to the substructure (foundation and tower). Therefore a significant cost reduction in foundation/tower would drastically improve the overall cost of offshore wind energy. This project intends to develop and demonstrate in operative environment a full scale prototype of a revolutionary substructure system for offshore wind turbines. The concept consists in a self-installing precast concrete telescopic tower which for the first time ever shall allow for crane-free offshore installation of foundations, towers and turbines, thus overcoming the constraints imposed by the dependence on offshore heavy-lift vessels. It will allow for a full in-shore preassembly of the complete system, which is key to generate a highly industrialized manufacturing process with high production rates and optimized risk control. The main benefits expected are: • 30-40% cost reduction (both CAPEX and OPEX). • Large water depth applicability range for deep offshore (>45m water depth). • Supports increased turbine size (5-8MW). • Allows for large scale fast industrial deployment of foundations. • Reduces dependence on costly and scarce installation vessels. • Improved asset integrity (durability) This solution will imply a radical step forward for cost-effective and industrially deployable deep offshore wind.

Keywords: off shore wind energy,craneless installation