Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Modular Electric Motor technology with integrated Digital Gears for increased driving performance (MEM-DG)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Finland
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-02-01
End date: 2017-05-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Electric motors have been around for more than a century but there has been little improvement in their mechanical construction, modularity and functionality. In electric vehicle applications, costly mechanical gears such as planetary gears and reduction gears are needed to make the system operate with required speed, rpm and torque. Mechanical gearboxes are often vulnerable for erosion and damage. Quantum Electric has developed a modular electric motor system with an integrated digital gear. The new electric motor is modular, compact and highly reliable and operates with high efficiency because of the innovative digital gear function. The digital gear extends motor efficiency up to several times comparing to traditional electric motors. All key components are modular which makes the motor easier to build, scale-up, customize and recycle. The universal component architecture saves money in raw materials by 20%. The digital gearbox extends both battery lifetime and driving range of the electric vehicles and it is more reliable in operation. This new range extender technology is remarkable benefit for the whole EV industry. Quantum is entering the electric motor market which is valued at an estimated €27 billion and intends to licence their technology to car manufacturers, primarily for application in Light Duty Vehicles. Within the overall innovation project, Quantum intends to optimise the engineering of the E-Gear system; industrialise its production; and perform an in-vehicle test to demonstrate and validate the technology.

Keywords: modular electric motor,pm synchronous electric motor,digital gear,matrix controller,electric vehicles,ev driving efficiency,ev driving range extension,low voltage regenerative braking systems
Social and neural moderators of the temperament-anxiety association: risk or protective factors? (Temperament-Anxiety)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-05-17
End date: 2024-06-30
Duration (months): 24.0
Total project cost (EUR): 187572.48
EU funding (EUR): 187572.48
Participants: 1
Project status: SIGNED

Why do some children develop anxiety while others do not? Behaviorally inhibited temperament is a strong risk factor for pediatric anxiety disorders, but not all children with behavioral inhibition develop anxiety. Identifying risk and protective factors in children with behavioral inhibition could improve early detection and prevention of anxiety disorders. I will focus on early adolescence, a pivotal developmental period for social and neural changes as well as for the development of anxiety. Notably, these changes unfold differently in boys and girls, which could influence risk for anxiety in sex-specific ways, thereby creating a female preponderance of anxiety. The goal of this study is to identify social and neural moderators of the temperament-anxiety association in boys and girls. This fellowship will be embedded in the Generation R Study at Erasmus University Rotterdam, a unique interdisciplinary prospective cohort following 1232 children since birth. Data on temperament (at 3 years), social and neural factors (from 7-13 years), and anxiety symptoms (at 13 years) have been collected. I will study social and neural factors in a novel way by focusing on multi-informant measures of peer relations, multi-modal quantification of in-lab social behavior, and developmental trajectories of resting-state functional connectivity. The large sample size provides the unique opportunity to examine sex differences. This fellowship will allow me to bring the knowledge and skills I acquired in the USA to the Netherlands. I will expand my line of research to include social and protective factors, longitudinal resting-state functional magnetic resonance imaging (fMRI) data, and epidemiological methods. I will learn how to foster a strong mutual connection between research and clinical practice. Finally, I will systematically set up outreach activities, especially for children, to bridge science and society. Together, this enhances my long-term career success in academia.

Keywords: anxiety,temperament,peer relations,fmri
The Promise of Land: Law, Land Restitution, and Indigenous Communities in Colombia (PROLAND)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2022-07-01
End date: 2026-07-01
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: SIGNED

Forcible land displacement due to the armed conflict has been prevalent in Colombia’s indigenous communities, which have been disproportionately affected. These communities are pushing back against the different intrusions on their land from multinational companies and armed groups in their goal of regaining possession of communally held territories. Additionally, current peace efforts in Colombia have set in motion a broad programme of land restitution. The project PROLAND examines the relationship between land restitution for indigenous communities and the Victims and Land Restitution Law of 2012, a juridical mechanism that formalises land ownership and, by this action, seeks to restore expropriated land. To date, however, only few indigenous communities have been granted land under the law. PROLAND will address why more cases have not been successfully concluded. The purpose of this project is to explore law on its own merits by interrogating its (in)efficacy and employing it heuristically to disclose the social, cultural, and political contexts that lead to this (in)efficacy. This project will engender new international interdisciplinary research on land restitution and establish the conceptual bases for studying land restitution by looking beyond the domination–resistance paradigm.
Landscapes of Loss: Mapping the Affective Experience of Deforestation Among Diverse Social Groups in the South American Chaco (lanloss)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-04-14
End date: 2024-07-13
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: SIGNED

Environmental upheavals generate losses across diverse sectors of society, and can heighten risks of social conflict (UNCCD 2017). Mapping the histories, memories and affective experiences of such losses among impacted communities could help expose incipient social tensions before they escalate. In the South American Gran Chaco, the rate of deforestation – which is among the highest in the world – is impacting the landscapes and livelihoods of indigenous, peasant, and white settler groups in both shared and competing ways. By working together with satellite data researchers, this multi-disciplinary project proposes an innovative collaborative approach to mapping the lived social and affective experience of rapid deforestation in the Gran Chaco through participatory memory-mapping: a process where local communities with antagonistic histories are invited to interact with the satellite data themselves, generating their own narratives of the various landscapes they have lost through a technique I call “affective mapping.” This collaborative approach enables both multi-disciplinary researchers as well as locals to develop new comparative understandings of how deforestation impacts communities in both shared and unequal ways, thus providing contexts for better understanding incipient tensions over resources.

Keywords: latin america,indigenous people,affect studies,environmental inequalities,settler colonialism,gran chaco
WIreLess LOWband communications: massive and ultra-reliable access (WILLOW)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Denmark
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-04-01
End date: 2020-03-31
Duration (months): 60.0
Total project cost (EUR): 1994411.25
EU funding (EUR): 1994411.25
Participants: 1
Project status: CLOSED

The overall objective of WILLOW is to make wireless communication a true commodity by enabling lowband communications: low-rate links for massive number of devices and ultra-reliable connectivity. This research effort is a major endeavour in the area of wireless communications, taking a different path from the mainstream research that aims at “4G, but faster”. Lowband communication is the key to enabling new applications, such as massive sensing, ultra-reliable vehicular links and wireless cloud connectivity with guaranteed minimal rate. The research in WILLOW is centred on two fundamental issues. First, it is the efficient communication with short packets, in which the data size is comparable to the size of the metadata, i.e. control information, which is not the case in broadband communication. Communication of short packets that come from a massive number of devices and/or need to meet a latency constraint requires fundamental rethinking of the packet structure and the associated communication protocols. Second is the system architecture in which graceful rate degradation, low latency and massive access can exist simultaneously with the broadband services. The principles from WILLOW will be applied to: (a) clean-slate wireless systems; (b) reengineer existing wireless systems. Option (b) is unique to lowband communication that does not require high physical-layer speed, but can reuse the physical layer of an existing system and redefine the metadata/data relationship to achieve massive/ultra-reliable communication. WILLOW carries high risk by conjecturing that it is possible to support an unprecedented number of connected devices and wireless reliability levels. Considering the timeliness and the relevance, the strong track record of the PI and the rich wireless research environment at Aalborg University, WILLOW is poised to make a breakthrough towards lowband communications and create the technology that will enable a plethora of new wireless usage modes.

Keywords: wireless communications,machine to machine communication,reliable communication,packet based communication
Cyclopropane Synthase Enzymes as Biocatalysts for Green Cyclopropanation Reactions (CycloproBio)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-01
End date: 2024-01-16
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 2
Project status: SIGNED

The cyclopropane ring is an important structural motif present in many pharmaceutical compounds and widely used as reactive building blocks in the synthesis of chemicals. Many synthetic strategies to access cyclopropanes have been developed to date, most of which typically require the use of potentially explosive diazo-carbene compounds as substrates. Even recently proposed enzymatic transformations, exploiting cytochromes P450 and myoglobin, require the use of stoichiometric carbene co-substrates, thus narrowing their industrial applications. The CycloproBio project aims to explore cyclopropane synthase (CS) enzymes as a potentially mild method for biocatalytic cyclopropanation. Cyclopropane synthases are SAM dependent transferase enzymes able to catalyse cyclopropanation of unsaturated phospholipids in bacterial membranes. Even if CS are common to most bacteria, many questions on factors affecting their substrate selectivity remain unanswered. Moreover, despite their potential, CS enzymes have not been explored yet as potential biocatalysts. This project will initially characterize the cyclopropane fatty acid synthase (CFAS) from E. coli which has been cloned, expressed and purified in preliminary work. The catalytic properties of the E. coli CFAS will be studied through the development of an appropriate activity assay, the investigation of its substrate specificity and the study of its physio-chemical properties. To broaden the study, genome mining for other CS enzymes from different bacterial species will be carried out to gain insight into the factors which affect the selectivity of these enzymes. Finally, new CS enzyme variants will be generated through rational mutagenesis of putative substrate binding residues. The data generated will provide fundamental information on the CS family. The primary aim of this project is to use this data to develop cyclopropanation biocatalysts for the sustainable synthesis of chemicals and pharmaceuticals.

Keywords: biocatalysis,cyclopropane,chemical engineering
Multimodal Scanning of Cultural Heritage Assets for their multilayered digitization and preventive conservation via spatiotemporal 4D Reconstruction and 3D Printing (Scan4Reco)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Reflective societies - cultural heritage and European identity
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Italy,Germany,Italy,Switzerland,Greece,Greece,United Kingdom
Call: Advanced 3D modelling for accessing and understanding European cultural assets (H2020-REFLECTIVE-7-2014, 2014)
Start date: 2015-10-01
End date: 2018-09-30
Duration (months): 36.0
Total project cost (EUR): 3762762.0
EU funding (EUR): 3417762.0
Participants: 9
Project status: CLOSED

Scan4Reco will develop a novel portable, integrated and modular solution for customized and thus cost-effective, automatic digitization and analysis of cultural heritage objects (CHOs), even in situ. A multi-sensorial 3D scanning - facilitated by a mechanical arm – will collect multi-spectra data and then, a hierarchical approach for 3D reconstruction of CHOs will be applied, enabling multi-layered rendering, advancing both analysis and 3D printing procedures. The goal will be to create highly accurate digital surrogates of CHOs, providing also detailed insight over their surface and also the volumetric structure, material composition and shape/structure of underlying materials, enabling rendering either via visualization techniques or via multi-material 3D printing. Material analyses will be applied, to understand the heterogeneous nature and complex structures of CHOs, to identify the broad and varied classes of materials and to understand their degradation mechanisms over time, deriving context-dependant ageing models per material. Uni-material models will be spatiotemporally simulated, based on environmental phenomena modeling, so as to collectively render imminent degradation effects on the multi-material CHOs, enabling prediction and recreation of their future appearance, as well as automatic restoration, reaching even back to their original shape. Scan4Reco will further facilitate conservation, by indicating spots/segments of cultural objects that are in eminent conservation need and require special care, while suggestions will be provided by a dedicated Decision Support System (DSS), over conservation methods that should be followed. All the above will be validated on real case scenarios involving heterogeneous objects of various sizes and materials, in 2 pilot real-world use cases. To enhance the accessibility of the digitized cultural objects to the scientific community, field experts and the general public, a virtual model of a museum will be launched.

Keywords: spatiotemporal 4d reconstruction,multisensorial sensing,scanning,conservation oriented decision support system,visualization,3d printing,material ageing,ageing models
Neighbourhood Change in a Comparative Context: a Social-Mobility Approach (Neighbourhood Change)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-12
End date: 2018-07-11
Duration (months): 22.0
Total project cost (EUR): 162798.9
EU funding (EUR): 162798.9
Participants: 1
Project status: CLOSED

Neighbourhood Change in a Comparative Context: a Social-Mobility Approach For decades, scholars have been seeking to understand why and how neighbourhoods change. Integrating different strands of the literature, it is suggested that neighbourhood transitions occur due to the interaction of cyclic dynamics generated by neighbourhoods’ local contexts, and structural transformations generated by higher level contexts. The interaction and the relative roles of these processes have not been investigated so far. Because research designs used to date cannot account for both types of effect, this proposal points to comparative research in contrasting regional and national contexts as a promising direction. Key methodological issues are identified in the current state-of-the-art with regard to the possibility of conducting effective comparative research on the topic: comparability of results, conceptualization of neighborhood change and distinguishing the relative impact of processes at different levels. The proposed research aims at addressing these issues in setting up a systematic approach to comparative analysis of neighbourhood change. The approach relies on the application of methods from social mobility research which has been tackling equivalent challenges. The approach will be implemented in an empirical comparative analysis of neighbourhood change in the Netherlands and Israel.

Keywords: neighbourhood change,neighbourhood transitions,socio spatial inequality
Improving kidney transplantation outcome with Renaparin® for patients with End-Stage Renal Disease by attenuating graft ischemia reperfusion injury (Renaparin)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Sweden
Call: Supporting innovative SMEs in the healthcare biotechnology sector (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2017-03-01
End date: 2020-05-31
Duration (months): 39.0
Total project cost (EUR): 2362681.25
EU funding (EUR): 2362681.25
Participants: 1
Project status: CLOSED

This project will validate the safety and efficacy of Corline Biomedical’s pharmaceutical compound Renaparin®, a novel cell replacement technology used to coat the lining of the blood vessels of kidneys prior to transplantation. Donor kidneys lack natural blood flow while awaiting transplantation. This can lead to ischemia (a shortage of oxygen and glucose supply to the kidney tissue). When connected to the recipient’s blood flow, this in turn leads to ischemia reperfusion injury (IRI). Given the alarming shortage of organs available for transplantation in the EU and internationally, the prevention of IRI has become a top priority for the transplantation community. Transplantation surgeons and nephrologists emphasise the pressing need for safe and effective technologies which can improve the outcome of kidney transplantation and extend donor criteria. Renaparin® is used when the kidney has been extracted from the donor and is stored in preservation solution awaiting transplantation. There, it binds to, replaces, repairs and protects damaged kidney cells on the endothelium of the vascular wall. As a result, a kidney is less likely to activate the host’s innate immune system, which increases the chances of organ survival and substantially reduces the likelihood of organ rejection. The research performed in preparation of further development of Renaparin® strongly supports the drug’s potential to increase the success of kidney transplantation. The activities proposed in this project will bring Renaparin® through a Phase I/IIa clinical trial in humans. The produced clinical safety data and preliminary clinical efficacy data will constitute the basis for further clinical development and commercialisation of the product. Corline’s strategic focus lies on establishing Renaparin® as a new cell replacement technology in kidney transplantation. This will constitute the cornerstone of Corline’s accelerated growth. The project is the key step to realize this strategy.

Keywords: kidney transplantation,vascular repair,endothelial protection,ischemia reperfusion injury iri,heparin
Northern Ireland SME Innovation Support Services 2014 (EENNI_INN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: United Kingdom
Call: INNOSUP (H2020-Adhoc-2014-20, 2014)
Start date: 2014-07-01
End date: 2014-12-31
Duration (months): 6.0
Total project cost (EUR): 17500.0
EU funding (EUR): 14000.0
Participants: 1
Project status: CLOSED

This proposal describes Invest NI’s response to the invitation, “Enhancing the Innovation management Capacity of SMEs by the Enterprise Europe Network”. The proposal describes our delivery of Key Account Management of SME Beneficiaries (KAM) and, “Enhancing the innovation management capacity of SMEs” (Innovation Services or IS).

Keywords: innovation capacity management