Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Neuromorphic Electronic Agents: from sensory processing to autonomous cognitive behavior (NeuroAgents)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Switzerland
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-09-01
End date: 2023-08-31
Duration (months): 72.0
Total project cost (EUR): 1999090.0
EU funding (EUR): 1999090.0
Participants: 1
Project status: SIGNED

Neural networks and deep learning algorithms are currently achieving impressive state-of-the-art results. In parallel computational neuroscience has made tremendous progress with both theories of neural computation and with hardware implementations of dedicated brain-inspired computing platforms. However, despite this remarkable progress, today’s artificial systems are still not able to compete with biological ones in tasks that involve processing of sensory data acquired in real-time, in complex and uncertain settings. One of the reasons is that neural computation in biological systems is very different from the way today's computers operate: it is tightly linked to the properties of their computational embodiment, to the physics of their computing elements and to their temporal dynamics. Conventional computers on the other hand operate with mainly serial and synchronous logic gates, with functions that are decoupled from their hardware implementation, and with discretized and virtual time. In this project we will combine the recent advancements in machine learning and neural computation with the latest developments in neuromorphic computing technology to design autonomous systems that can express robust cognitive behavior while interacting with the environment, through the physics of their computing substrate. To achieve this we will embed in robotic platforms microelectronic neuromorphic processors and sensors that implement biophysically realistic neural computational primitives and dynamics. We will adopt active-sensing and on-line spike-based learning strategies, context and state-dependent computation, and probabilistic inference methods for "programming" these neuromorphic cognitive agents to solve challenging tasks in real-time. Our results will lead to compact low-power intelligent sensory-motor systems that will have a large impact on service and consumer robotics, Internet of Things, as well as prosthetics and personalized medicine.

Keywords: neural networks,cognitive systems,biomimetics,computational neuroscience,embedded systems,deep netwroks,learning,neuromorphic
Real-time Adaptive Particle Therapy of Cancer (RAPTOR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Austria,Germany,Germany,Italy,Germany,Austria,Slovenia,Sweden,Switzerland,Netherlands,Netherlands,Denmark
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2021-03-01
End date: 2025-08-31
Duration (months): 54.0
Total project cost (EUR): 3967111.08
EU funding (EUR): 3967111.08
Participants: 13
Project status: SIGNED

The Real-time Adaptive Particle Therapy Of CanceR (RAPTOR) consortium comprises world-class research institutes, non-academic particle therapy (PT) centres and industrial providers of PT equipment, offering a platform for intercultural, interdisciplinary and intersectoral training of early stage researchers (ESRs) in the field of medical physics with a focus on real-time adaptive PT. This comprehensive expertise and infrastructure is required to address and solve challenges in the clinical implementation of real-time adaptive PT. PT is an advanced type of radiotherapy used to treat a constantly rising number of cancer patients. PT allows to target tumour with a high accuracy while sparing healthy surrounding tissue from dose. However, changes in anatomy or positioning and organ motion give rise to uncertainties which need to be further minimized to exploit the full benefits of PT. Adapting PT plans in real time has the potential to provide truly personalized treatments, allowing for better target control and less toxicity. A move towards wide clinical implementation of adaptive PT approaches is currently prohibited by (i) stepwise treatment workflows that are time-consuming and largely manual, (ii) the inflexibility of commercial PT equipment, and (iii) the wide range of PT equipment and protocols. RAPTOR ESRs will conduct research projects at both academic and non-academic health care facilities which will sharpen their focus on clinical needs with respect to real-time adaptive PT. The active involvement of industry ensures that the transfer of industry-relevant skills is an integral part of individual ESR projects. This will guarantee rapid translation of clinical needs into innovative and marketable solutions. RAPTOR aims to train a new generation of researchers, enabling a paradigm shift from treatment approaches that are manual and stepwise to those that are automatic and seamless, while assuring standardized clinical implementation of real-time adaptive PT.

Keywords: particle therapy,medical physics,real time adaptive workflows,medical imaging,image processing,treatment verification,quality assurance,automatization,industrialization,intersectoral training
Development and disease of the renal tract (RENALTRACT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Germany,Germany,Finland,France,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-06-01
End date: 2019-05-31
Duration (months): 48.0
Total project cost (EUR): 3137377.32
EU funding (EUR): 3137377.32
Participants: 9
Project status: CLOSED

The renal tract (kidneys, the ureters, bladder) is a complex organ system crucial for maintaining the body homeostasis. This organ system arises from different precursor pools through a complex program of patterning, differentiation and morphogenesis in embryonic development. Alteration of this program leads to renal tract malformations (RTM) that are incompatible with a healthy life. While some of these RTM can be surgically corrected, others develop into chronic entities that may lead to renal failure; the burden for the patients and for the socio-economic impact for the health systems is immense. Although congenital RTM are amongst the most frequent human birth defects, the different programs that direct normal and pathological development have remained poorly understood. The RENALTRACT training network aims to address these deficits and provide a better understanding of the programs that underlie RTM and provide solutions to clinical problems. This shall be achieved by using a multidisciplinary team approach with partners working in complementary disciplines (developmental biology, renal physiology, Omics, clinical medicine). RENALTRACT has unique and distinguishing features by uniting studies on components of the urinary tract, by building a bridge between basic and clinician scientists and by combining state of the art methods from a number of complementary fields in a variety of animal models. RENALTRACT aims to establish a first class multidisciplinary training program for outstanding Early-Stage Researchers (ESRs) to provide a group of young scientists with expert knowledge to envision and embark on novel therapies of renal tract malformations in the future. ESRs will benefit from an excellent working environment with state-of-the-art technologies and supervision by international leaders in the field and an inter-disciplinary approach. This will be complemented by intersectoral exposure and exchange between the RENALTRACT public and private participants.

Keywords: animal development,organ physiology,mol biology and interactions,renal tract,urogenital system,ureter,bladder,cakut,gene identification,mol pathways,disease modeling,omics
Nanoscale Aromaticity and Supramolecular Electronic Materials (ARO-MAT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2020-10-01
End date: 2026-03-31
Duration (months): 66.0
Total project cost (EUR): 2491625.0
EU funding (EUR): 2491625.0
Participants: 1
Project status: SIGNED

ARO-MAT will target emergent cooperative electronic and magnetic phenomena in molecules with dimensions of 5–25 nm (i.e. as big as many proteins). The project will develop supramolecular architectures with large pi-systems and well-defined geometries, in which the frontier orbitals coherently delocalize charge over the whole nanostructure. Aromaticity is a key emergent phenomenon; it can be defined as the ability of a cyclic molecule to sustain a ring current when placed in a magnetic field. Until recently, it was thought that aromaticity is restricted to small molecules, with circuits of less than about 22 pi-electrons. Anderson has shown that circuits of more than 160 pi-electrons (circumference > 15 nm) can exhibit strong aromatic ring currents. Testing even larger rings will elucidate the link between aromaticity and the persistent currents found in non-molecular mesoscopic rings (diameter 50–500 nm). ARO-MAT will explore the effects of molecular size and topology on nanoscale aromaticity. Other emergent phenomena to be addressed include the formation of open-shell singlet polyradical ground states, magnetic bistability in systems with many paramagnetic metal centers, and the control of charge transport through single-molecule devices by quantum interference. This multidisciplinary project combines organic synthesis, supramolecular chemistry, theory, electronic structure calculations, NMR and EPR spectroscopy, magnetochemistry, molecular electronics and low-temperature charge transport experiments. The core objective is to create low band gap materials with unprecedented electronic and magnetic properties, and to understand the structure-property relationships governing the behavior of these new materials. Most of the target structures are based on metalloporphyrins because of their redox activity, stability, structural versatility, suitability for template-directed synthesis and ability to position multiple strongly coupled paramagnetic metal centers.

Keywords: supramolecular,templates,cooperativity,self assembly,macrocycles,porphyrins,molecular materials,pi systems
Spatio-temporal Stochastic Models for Phenotype and Gene Regulation by the Human Papillomavirus (STEPV)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-02-07
End date: 2023-08-06
Duration (months): 18.0
Total project cost (EUR): 159700.32
EU funding (EUR): 159700.32
Participants: 1
Project status: SIGNED

Human papillomaviruses (HPVs) cause a range of serious diseases, with particular regard to cervical cancer, most anal cancers and half of head and neck cancers, and the need for new and effective antiviral therapies is of paramount importance. Important advancements regarding the HPV infection, throughout the infected epithelium, have been recently made. However, a full mechanistic understanding of how stochastic and dynamical properties of the HPV gene network interact with the cellular circuitry that controls proliferation/differentiation and cell-to-cell communication affects responses at the single cell and tissue level during infection is lacking. A better understanding of these aspects is critical to understand viral persistence, cancer progression, and to develop novel strategies for antiviral therapies. Mathematical models, developed under rigorous mathematical and biological assumptions, can be of great help in generating optimal solutions to these problems. STEPV project aims at improving the current available frameworks for stochastic tissue-level mathematical modeling, by tackling their limitations and specialize them in the context of HPVs, as well as to improve clinical/biological discoveries about HPVs infection. The specific goals are: (1) development of novel spatio-temporal modeling frameworks in order to describe HPVs gene expression and its connection with the phenotype control; (2) use of the developed models to understand the phenotype regulation by oncoproteins, understand viral persistence and propose novel antiviral strategies. By achieving these goals, STEPV will provide, for the first time, innovative modeling frameworks in the field of the computational systems biology applied to the context of HPVs infection, allowing quantitative and noninvasive tools to deeply investigate still elusive mechanisms, regarding HPVs infection, as well as investigate inaccessible or poorly understood clinical/biological scenarios.

Keywords: spatio temporal mathematical models,cell to cell communication,cell phenotype,papillomavirus,cell differentiation,cell proliferation,computational disease pathology,computational virology
Picturing Modernist Future: Women Illustrators and Childhood Conceptions in Socialist Yugoslavia (SOC-ILL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Slovenia
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2024-09-30
Duration (months): 36.0
Total project cost (EUR): 243060.48
EU funding (EUR): 243060.48
Participants: 1
Project status: SIGNED

The SOC-ILL action introduces the first systematic comparative interdisciplinary investigation into women illustrators in the Socialist Federal Republic of Yugoslavia (SFRY, 1945–1991), paying attention to all former Yugoslav contexts and combining art and literary historical and theoretical approaches with cultural studies for novel critical insights into socialist aesthetic education and subjectivation of children, especially in relation to gender. Through the examination of multiple archives and interviews with older generations of professionals working within the feminized sector of publishing for minors, the action works against their disappearance before any academic documentation can take place. The action entails 3 main objectives: (i) To explore and contextually interpret distinctive childhood- and gender conceptions within Yugoslav publishing for minors; (ii) To map the practice of women illustrators for minors at the intersection between local, regional and international artistic and aesthetic education movements; (iii) To intervene into academic “archiving” by supporting a more complex understanding of socialist modernist aesthetic education and subjectivation. Thus the action contributes to redefinition of the relation between communicative and cultural memory of the European socialist past in the broader fields of Yugoslav, Slavonic, and socialist studies and the disciplines of art, literary and cultural history. These objectives can only be achieved in the proposed collaboration, with my cross-sectorally situated research – my expertise on (post)socialist women’s authorship, i.e. a pioneering thesis on gender, war, and memory and a variety of international scientific and art events – and the beneficiary’s distinctive expertise within the emerging (post)Yugoslav studies. This unique transfer will ensure a notable academic footprint, my full re-integration into science and foster impactful scientific cognizance within a broad range of stakeholders.

Keywords: socialist yugoslav aesthetic education,childhood and gender in illustration,socialism and subjectivation
Two-Dimensional Chemistry towards New Graphene Derivatives (2D-CHEM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Czechia
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-06-01
End date: 2022-12-31
Duration (months): 79.0
Total project cost (EUR): 1831102.5
EU funding (EUR): 1831102.5
Participants: 1
Project status: CLOSED

The suite of graphene’s unique properties and applications can be enormously enhanced by its functionalization. As non-covalently functionalized graphenes do not target all graphene’s properties and may suffer from limited stability, covalent functionalization represents a promising way for controlling graphene’s properties. To date, only a few well-defined graphene derivatives have been introduced. Among them, fluorographene (FG) stands out as a prominent member because of its easy synthesis and high stability. Being a perfluorinated hydrocarbon, FG was believed to be as unreactive as the two-dimensional counterpart perfluoropolyethylene (Teflon®). However, our recent experiments showed that FG is not chemically inert and can be used as a viable precursor for synthesizing graphene derivatives. This surprising behavior indicates that common textbook grade knowledge cannot blindly be applied to the chemistry of 2D materials. Further, there might be specific rules behind the chemistry of 2D materials, forming a new chemical discipline we tentatively call 2D chemistry. The main aim of the project is to explore, identify and apply the rules of 2D chemistry starting from FG. Using the knowledge gained of 2D chemistry, we will attempt to control the chemistry of various 2D materials aimed at preparing stable graphene derivatives with designed properties, e.g., 1-3 eV band gap, fluorescent properties, sustainable magnetic ordering and dispersability in polar media. The new graphene derivatives will be applied in sensing, imaging, magnetic delivery and catalysis and new emerging applications arising from the synergistic phenomena are expected. We envisage that new applications will be opened up that benefit from the 2D scaffold and tailored properties of the synthesized derivatives. The derivatives will be used for the synthesis of 3D hybrid materials by covalent linking of the 2D sheets joined with other organic and inorganic molecules, nanomaterials or biomacromolecules.
Pilot line for micro-transfer-printing of functional components on wafer level (MICROPRINCE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Public-private partnerships
Destination: Electronic Components and Systems
Action type: Innovation actions
Partnership: ECSEL (Art-187)
Countries involved: Germany,Ireland,Germany,Ireland,Ireland,Germany,Germany,Switzerland,Belgium,Belgium,Belgium,Belgium
Call: ECSEL Key Applications and Essential Technologies (IA) (H2020-ECSEL-2016-2-IA-two-stage, 2016)
Start date: 2017-04-01
End date: 2020-09-30
Duration (months): 42.0
Total project cost (EUR): 10854745.94
EU funding (EUR): 2614618.01
Participants: 14
Project status: CLOSED

The “Pilot Line for Micro-Transfer-Printing of Functional Components on Wafer Level” project (MICROPRINCE) is focused on creation of a pilot line for heterogeneous integration of smart systems by micro-transfer-printing (µTP) in a semiconductor foundry manufacturing environment. Functional components like processed III/V devices, optical filters, and special sensors will be transfer printed to demonstrate the capabilities of the technology and pilot line. Based on several EU and national research activities demonstrating successfully the feasibility of µTP technology in a scientific and laboratory environment, the MICROPRINCE consortium has the goal to setup the first worldwide open access foundry pilot line for heterogeneous integration by µTP and to demonstrate its capability on five defined target application scenarios. For this purpose, the consortium consisting of 13 partners from four different countries combine their expertise along the value chain from materials and equipment, technology and semiconductor processing, integrated circuit and system design, test and application. The partners are industrial companies incl. SME’s, accompanied by leading research institutes with a clear focus on production and application in Europe. The working principle of the micro-transfer-printing technology is to use a micro-structured elastomer stamp to transfer microscale functional components from their native substrates onto non-native substrates. The lateral dimensions of the functional components can range from a few microns to a few hundreds of microns with thicknesses of only a few microns. The native substrate contains the functional components to be printed and is flexible in size and material. The MICROPRINCE pilot line is acting as a regional and nationwide competence cluster for a novel technology with European dimensions for heterogeneous system integration and supports the ECS industry to reach leadership in key applications.

Keywords: micro transfer printing,heterogeneous integration,v materials