Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Elucidation of the different reaction mechanisms and pathways offered by the AOR (EluMecAOR)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-01-01
End date: 2024-12-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: CLOSED

Green hydrogen produced from renewable electricity through water electrolysis can be converted via the energy-efficient Haber-Bosch process into green ammonia (NH3). Currently, large industrial efforts are under way to scale up production globally. With an expected surge in green NH3 supply, the question arises whether the stored energy can be released electrochemically in NH3 fuel cells. However, so far, high ammonia oxidation reaction (AOR) overpotentials and particularly a NO-poisoning mechanism have prevented application of low-temperature NH3 fuel cells. Therefore, this project focuses on the elucidation of key reaction mechanisms and pathways offered by the AOR (EluMecAOR). In particular, I hypothesize that metal oxide modifications on the Pt surface offer a way to reduce the AOR overpotential independently from the deactivation mechanism. To test this hypothesis, the catalyst surface composition will be modified using atomic layer deposition (ALD) of metal oxide clusters and characterized in detail, including fundamental electrochemical and operando microscopy and spectroscopy methods. This Marie Curie Fellowship combines my own expertise on fundamental Pt electrochemistry and the effects of metal oxide modifications with the world-leading expertise of the Interface Science Department at the Fritz-Haber Institute of the Max-Planck-Society on controlled nanoparticle synthesis and operando electrocatalyst research.

Keywords: electrocatalysis,ammonia electro oxidation,metal oxides,nanoparticle atomic layer deposition,green hydrogen,operando spectroscopy and microscopy
Gender and Intersectionality in the History of Political Thought-The Cases of Mary Hays and George Wallace (GenderHPT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Finland
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 215534.4
EU funding (EUR): 215534.4
Participants: 1
Project status: SIGNED

The overall goal of this research is to offer a novel account of the origins of proto-feminist and antislavery ideas in British political thought based on hitherto overlooked writers and sources. Political philosophers have been long discussing the concepts of liberty, equality, and justice, and political theorists are now rethinking urgent questions of gender and race. Yet there is still little conversation between them or investigation of how these notions have always been structured in response to one another. The discipline of history of political thought is well placed to bridge this gap and to trace the intertwined development of these ideas, as this research aims to show. At the centre of this project stands Mary Hays (1759–1843), one of the first advocates of women’s rights in Britain. Hays, it will be argued, should be considered a major starting point of a tradition of European feminist freethought which championed radical pro-women, anti-racist, and antislavery arguments and integrated them with new and nuanced conceptions of equality, liberty, and emancipation. A second case study of this research is George Wallace (1727–1805) who published the first essay in Britain which explicitly advocated total and immediate abolition of both slavery and the slave trade (1760). Wallace, too, offered an innovative and utopian account of equality, and his categorical rejection of slavery entailed a historic shift in common interpretations of Roman law, natural law, and the law of nations. Among the outputs of this research will be a monograph, provisionally titled Politics of Freethinking: Religion, Gender, and Slavery in Eighteenth-Century Britain, as well as a series of individual chapters and articles aimed at leading peer-reviewed journals. Several academic and public activities will be held in collaboration with scholars of gender and critical race studies at Jyväskylä to disseminate and communicate these findings.

Keywords: feminism anti slavery freethought eighteenth century britain enlightenment mary hays george wallace reception studies
Next Generation Quasi-Adiabatic Propagator Path Integral (Quapi) Methods for Condensed Phase Quantum Dynamics (NG-Quapi)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1999491.0
EU funding (EUR): 1999491.0
Participants: 1
Project status: SIGNED

The inevitable interaction of a quantum system with the environment leads to energy relaxation and decoherence which can result in novel phenomena and opportunities not present in isolated quantum systems. Of particular interest is the non-equilibrium relaxation dynamics subject to non-Markovian memory and at strong interaction with the environment. In such situations, novel and generally applicable computational methods are necessary for precise and reliable simulations of the many body dynamics of open quantum systems. For this purpose, a hierarchy of methodological developments is proposed within the framework of the quasi-adiabatic propagator path integral (Quapi) method that address (i) the generalization of the method to more complex environments, (ii) its numerical efficiency and scalability, and (iii) employ neural networks to leverage algorithm performance. Finally, (iv) a quantum algorithm-based strategy is pursued for accelerated numerical propagation algorithms on near-term quantum devices. The hierarchy of developments facilitates simulations of condensed phase quantum dynamics for more complex systems and ever complex environments to address highest relevance open questions and research objectives in the understanding of condensed phase quantum dynamics, specifically, if the interactions of a system with its environment potentially can affect the system’s coherence, the underlying mechanisms leading to complex many body phenomena and the possibility of control of the system dynamics and its decoherence. Ultimately, the algorithm developments and novel conceptual approaches will yield a comprehensive numerical path integration software platform for condensed phase quantum dynamics simulations that has groundbreaking potential by facilitating extremely challenging simulations that are not yet possible on classical computers or only envisioned on tailor made quantum devices.

Keywords: open quantum systems,quantum dynamics,non markovian memory,solar energy conversion,solvated electrons,superconducting qubits
Scaling Social Entrepreneurship and Innovation: Zooming in on Multidisciplinary Interconnected Challenges (SEIZMIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Denmark,Iceland,Italy,Germany,Austria,Spain,France,Ukraine,Netherlands
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2024-10-01
End date: 2028-09-30
Duration (months): 48.0
Total project cost (EUR): 4267576.8
EU funding (EUR): 4267576.8
Participants: 18
Project status: SIGNED

The SEIZMIC Doctoral Network represents an ambitious endeavor to catalyze scalable social entrepreneurship (SE) across Europe. Addressing a critical gap in the social entrepreneurship landscape, SEIZMIC aims to unravel the complex dynamics of scaling social enterprises, focusing on external replication and imitation to magnify societal impact. This project is particularly pertinent given the noted scarcity of SE scaling, a phenomenon that limits the societal reach of innovative solutions. At the core of SEIZMIC's mission is the development of an interdisciplinary and cross-sectorial research framework. The network harnesses expertise from diverse fields such as entrepreneurship, finance, education, and technology management, aiming to synthesize these into a cohesive theoretical framework. This integrative approach is designed to overcome entrenched interdisciplinary barriers and equip a new generation of researchers with the competencies necessary for advancing SE scaling. The research program is structured around five key Work Packages (WPs), each addressing a distinct aspect of SE scaling: Shifting paradigms to Social Business Model Design (WP2), Impact Investing for SE Scaling (WP3), Competencies and Education for SE Scaling (WP4), and the Role of Digital Ecosystems and AI in SE Scaling (WP5). These WPs involve innovative methodologies, including case studies, surveys, AI-driven mentoring, and digital transformation analyses, ensuring a comprehensive exploration of SE scaling.

Keywords: social entrepreneurship,social business models,impact investing,social innovation,competencies,education,virtual mentoring
Innovative forensic trace investigation via microfluidics and single-cell genomics (CapCell)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Fighting Crime and Terrorism
Action type: Research and Innovation actions
Countries involved: Netherlands,Belgium,Portugal,Austria,Estonia,Italy,Switzerland,Denmark
Call: Open Topic (HORIZON-CL3-2024-FCT-01, 2024)
Start date: 2025-10-01
End date: 2029-09-30
Duration (months): 48.0
Total project cost (EUR): 4499308.75
EU funding (EUR): 4499308.75
Participants: 13
Project status: SIGNED

Sexual violence affects 1 in 10 women across Europe and has increased by 10% alone in 2021-2022. Most cases involve complex biological mixtures containing cells from the victim and perpetrator(s). Current forensic methods struggle to isolate individual DNA profiles, leaving many cases unresolved and perpetrators unprosecuted. Addressing these limitations is critical to improving evidence interpretation, ensuring justice for victims, and reducing societal impacts. CapCell aims to deliver a new approach to improve forensics and lawful evidence collection with innovative microfluidics and single-cell genomics technologies to overcome the limitations of mixed DNA evidence. Specifically, we will develop the CapCell toolkit comprised of ten easily integrated modules that capture, select, isolate, sequence and interpret individual cells of interest. We will co-create novel strategies and best practices with end-users and industry to improve evidence collection from postcoital swabs and contact traces. Recovered intact cells from male contributors will then be selected and isolated using innovative mobile microfluidic devices. By employing novel concepts, we will advance follow-up DNA sequencing assays and analysis tools to target diverse forensic biomarkers with single-cell resolution. We will align interpretation frameworks to suit single-cell DNA analysis and leverage machine learning to automate the forensic process. Eventually, CapCell will achieve its goal by validating and implementing the new toolkit (TRL5-7) in the relevant end-user environment, with the support of several forensic science institutes and police forces. To reach its ambitious objectives, CapCell brings together an experienced intersectoral consortium of 13 partners from 8 European countries, with complementary expertise in forensic genomics, biosensor technology, bioinformatics, statistics and technology prototyping. Ultimately, CapCell will contribute to a safer and healthier society across Europe.

Keywords: forensic genetics human identification dna profiling sexual violence trace evidence,dna mixtures microfluidics cell isolation single cell genomics nanopore sequencing dna interpretation
VALues and dependence of society on pollinatORs (VALOR)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Research and Innovation actions
Countries involved: United Kingdom,Sweden,Germany,Poland,Spain,Netherlands,Austria,Finland,Bulgaria,Belgium,Australia,China
Call: Dependence of society and the economy on pollinators (HORIZON-CL6-2024-BIODIV-01, 2024)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 6498316.75
EU funding (EUR): 6498316.75
Participants: 16
Project status: SIGNED

VALOR is a multi-actor project that will develop a comprehensive systems based approach to develop a deeper understanding of the cascading impacts of pollinator shifts from flower to fork (and beyond). Our work spans seven localised “focal regions” across Europe, where we will explore the impacts of pollinator shifts on ecosystems, farm businesses and local communities through primary research and modelling. These will be supported by broader synthesis and modelling tasks to determine the impacts of pollinators on value chains, international trade and nutrition and highlight the risks to ecosystems and natural capital across Europe, under different co-developed future scenarios. VALOR aims to empower actors to better understand their relationship with pollinators and will produce a number of co-developed tools for landowners businesses and policymakers to better understand these risks and easily undertake their own studies by replicating our methods and employing our models. Throughout the project, VALOR will work through our existing networks of policy and business collaborators to maximise the engagement with our outcomes, datasets and tools, build synergies with the wider pollinator research community and effectively mainstream pollinators into decision-making at all levels throughout Europe.

Keywords: pollinators,ecosystem services,biodiversity,farm business,sociology,value chain,trade,nutrition,participatory research,scenarios,tools
Systematic study of IgG4-autoimmune diseases to develop new treatment strategies (IgG4-TREAT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Austria,France,Germany,Netherlands,Türkiye,Greece,Italy,Czechia,Spain
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2023-09-01
End date: 2027-08-31
Duration (months): 48.0
Total project cost (EUR): 2729711.31
EU funding (EUR): 2626812.0
Participants: 20
Project status: SIGNED

IgG4-autoimmune diseases (IgG4-AID) are rare but collectively correspond to a significant group of devastating diseases affecting many different organs, e.g. skin, brain, nerves and kidney in patients that often remain unresponsive to current treatments. IgG4-AID have commonalities indicating a shared underlying immunopathogenesis that make a joint approach to identify new therapeutic targets and test new treatment strategies feasible and necessary. We hypothesize that genetic risk factors and a dysregulated immune response may lead to an increased susceptibility to produce antibodies targeting self-proteins. These are of a special subclass called IgG4, which are usually harmless but can cause disease in these patients by interfering with normal functions in the body. We are the first consortium that aims to study IgG4-AID comparatively, including pathogenic IgG4, and the cells, molecules and mechanisms involved in IgG4 autoantibody production, using an explorative multi-omics approaches in combination with state-ofthe- art cell and molecular biology methodology. We will establish a new humanized mouse model of IgG4-AID for the development and testing of a novel immune-apheresis based therapy aimed as immediate relief therapy for all IgG4-AID patients. Our innovative training program combines university-based and multidisciplinary research-based training with state-of the art web-based training and in-person trainings by the academic and non-academic sector. We aim to foster a new generation of experts in IgG4-AID that are 1) are highly employable both in the academic and industry sectors and qualified for innovative multidisciplinary translational research with a focus on biomedical product development and 2) equipped with the skillsets for digitalization, awareness for gender equality and diversity and competent in sustainable research and innovation approaches to address current and future challenges, such as climate change, social inequalities and pandemics.

Keywords: igg4 autoimmune diseases,animal models,biomarkers,neuroimmunology,autoantibodies,myasthenia gravis,lgi1,autoimmune encephalitis
Approach for Unloading Knee Joint Cartilage Pressure: Potential Applications in Post-Surgical Rehabilitation (KNEEUL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-03-01
End date: 2028-02-29
Duration (months): 24.0
Total project cost (EUR): 242260.56
EU funding (EUR): 242260.56
Participants: 1
Project status: SIGNED

More than 520 million people worldwide suffer from arthritis, with 60% being women. The knee joint is the most commonly affected, accounting for 365 million cases. Cartilage repair surgery, a promising technique, requires strict control of joint pressure during the post-surgery recovery period. The KNEEUL project, a preclinical technology initiative, aims to develop a knee joint brace that unloads pressure on knee cartilage after surgery, thereby shortening patient recovery time. This type of wearable device, offering such functionality, is unprecedented and presents two key challenges: 1. Developing strategies to effectively unload knee cartilage pressure, and 2. Achieving non-invasive real-time estimation of knee cartilage pressure. KNEEUL will be conducted with the Laboratoire d’Informatique, de Robotique et de Microélectronique de Montpellier (LIRMM) as the host institution, in collaboration with the Laboratoire de Mécanique et Génie Civil (LMGC) and the Centre Hospitalier Universitaire (CHU). The project will address these key challenges through two main approaches: 1. Developing a wearable orthosis that effectively unloads inner knee joint pressure through non-invasive distraction of the femoral from the tibial part. This includes: 1) designing the pressure unloading mechanism, 2) creating a stiffness-adjustable attachment mechanism, and 3) developing and realizing the prototype. This research integrates mechanical transmission, biomechanics, and materials science. 2. Achieving real-time, non-invasive estimation and feedback of knee cartilage pressure. This includes: 1) implementing portable measurement hardware, 2) developing a pressure estimation model using multi-sensor data fusion, and 3) integrating the prototype and validating the research approach. This research integrates biomedical knowledge, sensing technology, and intelligent algorithms.

Keywords: wearable robotjoint cartilage pressuremechanism designnon invasive pressure sensing
Understanding Sixth Extinction as a Hermeneutical Challenge (HERMEX6)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: SIGNED

HERMEX6 aims to elucidate the role of interpretative processes in our dealing with the global reduction of biodiversity, commonly referred to as “sixth extinction”. The contention is that, in this case, the difficulty to attribute value to scientifically attested facts is a problem of interpretation: we lack qualitative frames to elaborate the extinction event and the knowledge that describes it. The project intends to define, analyse and address this set of issues with regard to contemporary European societies. After testing the initial hypothesis, the research project will formulate an innovative and interdisciplinary approach to the epistemic status of sixth extinction. HERMEX6 addresses a European top priority (with reference to the EU 20230 Biodiversity Strategy) and aims to fill a major gap in environmental humanities: it is therefore particularly timely. The whole project is tailored to the scientific profile of the candidate and to the characteristics of the host institution, the Pompeu Fabra University (UPF). The project is planned to provide the candidate with an increased set of notions and skills and to sensibly boost the candidate’s career perspectives. UPF is an internationally renowned environment with several groups and initiatives addressing complex ecological problems in a transdisciplinary perspective. The indicated supervisor, Professor Santiago Zabala, is a leading expert in hermeneutics and philosophy of environmental emergencies. In its more far-ranging implications, HERMEX6 aspires to improve science communication and the uptake of scientific results, raise collective awareness, inform more effective conservation programmes and generate added value in the field of policy guidance and advisory.

Keywords: sixth extinction biodiversity loss environmental communication environmental hermeneutics