Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
rethinking COASTal landSCAPES with climate-resilient interventions: systemic land-to-sea solutions (COAST-SCAPES)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Adaptation to climate change
Destination: Adaptation to climate change
Action type: Innovation actions
Countries involved: Spain,Romania,Italy,Portugal,Bulgaria,Germany,Mozambique,Colombia,Morocco,Senegal,Ukraine,Viet Nam,Ecuador,Australia,United Kingdom
Call: Systemic and cross-sectoral solutions for climate resilience, tailored to the local needs of regions and local authorities (HORIZON-MISS-2024-CLIMA-01, 2024)
Start date: 2025-09-01
End date: 2029-08-31
Duration (months): 48.0
Total project cost (EUR): 8833698.75
EU funding (EUR): 8565911.25
Participants: 31
Project status: SIGNED

Coast-Scapes (rethinking COASTal landSCAPES with climate-resilient interventions: systemic land-to-sea solutions) proposes to rethink land-coast-sea systems under climate change for enhanced resilience and biodiversity gains. We shall co-design systemic resilience solutions for coastal landscapes using transdisciplinary indicators, early and climatic warnings, business models and knowledge-based maintenance to reduce climatic risks and improve land to sea environments. We propose nature-based-solutions (NbS) suited to a broad range of coastal archetypes, governance, climates and resilience deficits, sequenced along resilience-through-adaptation pathways. Such solutions, supported by governance transformation and cross-sectoral engagement, will be applied by regions and communities empowered by an unprecedented combination of technical tools, financial models and social commitment. Coast-Scapes will promote NbS for a climatic resilience compatible with biodiversity gains and existing infrastructure constraints, seeking a reduced environmental footprint under natural resources that are scarce in quantity and quality. Social and technical innovation, associated to a governance shift, will make systemic resilience operational and fill the implementation gap at a pace commensurate with climate change acceleration. The selected Core Pilot regions/communities feature climate sensitive natural/human assets, controlled by land-coast-sea interactions and acting as large-scale demonstrators of scalable resilience plans for replication and export. These plans aggregate Science, Policy, Industry, Society and Environment actors with administrations responsible for local implementation, organised as resilience platforms and linked in a Regions and Communities Board. Resilience solutions will be monitored/maintained/marketed with the project, new standards and business models, for a resilience build up commensurate with unfavourable climate/human stressors.

Keywords: land coast sea,systemic resilience,climate adaptation,pathway,nbs,early climatic warnings,indicators,solution marketplace,monitoring,maintenance,replicability,scalability,transdisciplinary
Towards loop splitting amplitudes and collinear factorisation breaking (COLLINEAR-FRACTURE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-05-01
End date: 2025-08-31
Duration (months): 28.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: SIGNED

The groundbreaking discovery of the Higgs boson at the Large Hadron Collider rang the bell for the beginning of a new era of particle physics. Naturally, the ever increasing precision data from experiments demand precise theory predictions for many observables to test the ultimate validity of the Standard Model (SM); any significant deviations from the SM predictions will hint for new physics. Quantum chromodynamics (QCD) being the most fascinating non-Abelian gauge theory provides a promising platform in achieving this goal through higher order perturbative computations in powers of the strong coupling. Process independent singular elements associated to QCD factorisation of scattering amplitudes in both soft and collinear limits, also known as splitting amplitudes, are the key elements in organising and automating these higher order calculations for the theory prediction of a general jet observable. So, the high relevance of these splitting amplitudes strongly motivates the researcher for an ambitious proposal on further improving their theoretical accuracy. In particular, through this proposal the researcher will investigate the soft-collinear splitting amplitudes required to predict a jet observable at next-to-next-to-next-to-leading order (N3LO). The researcher will also be exploring the intriguing concepts of collinear factorisation breaking and its effect on the prediction of an experimental measurable quantity. Upon successful, this project will contribute to the purpose of bringing down the theory uncertainties to 1\% level together with many new ideas and techniques which will assist the researcher to create an independent future career and contribute to tighten the grip on N3LO calculation tools.

Keywords: lhc,hadronic colliders,strong interactions,scattering amplitudes,collinear factorisation
Magnetogenesis from Axion-SU(2) Inflation and applications to Gravitational Waves (MASUGRAV)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-01
End date: 2025-09-30
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 1
Project status: CLOSED

Magnetic fields are ubiquitous in our Universe. The question of their origin and subsequent evolution is a challenge for modern cosmology. Recent bounds on magnetic fields from blazar observations, together with the requirement for initial “seed” field for dynamo and compression amplification mechanisms motivate the study of possible primordial origins of magnetic fields. This project combines expertise in early universe physics with an expertise in astrophysics, magnetohydrodynamics and advanced numerical tools to study the production of magnetic fields in models of axion inflation coupled to the Standard Model of particle physics - so-called axion-SU(2) inflation. The results of this project will trace the origin of magnetic fields from the early to the present-day universe and confront the axion-SU(2) magnetogenesis by cross-correlating cosmic microwave background and blazar observations. To achieve this I will go beyond the current understanding of the simpler so-called axion-U(1) magnetogenesis models widely studied until now, and study the viability of chiral magnetic field production in the axion-SU(2) case. Furthermore, I will develop new numerical tools to determine how the presence of feedback mechanisms affect magnetogenesis. I will also compute the spectrum of gravitational waves generated by axion-SU(2) models in the radiation-dominated era of the early universe, and compare it to other known sources of gravitational waves such as cosmic strings to understand potential differences in the observational predictions. My experience in early universe physics together with the present world-leading expertise in magnetohydrodynamics at Nordita make it an ideal place for a two-way transfer of knowledge essential for the implementation of this project. This project aims to bridge astrophysics and early universe physics, and to develop cutting-age numerical tools that may also be applicable in quantum physics and condensed matter physics.

Keywords: cosmology,early universe,cosmic inflation,magnetogenesis,magnetic fields,gravitational waves,primordial,axion,gauge fields su 2,non abelian,astrophysics,magnetohydrodynamics,chirality
The genetic and epigenetic determinants of enhancer-promoter contacts in mammalian evolution (EVOCHIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Gene regulation is fundamental to biological diversity, driving differences between cell types within an organism and contributing to variation between species. DNA regions known as enhancers play a critical role in this process. Enhancers can be located millions of base pairs away from the genes they regulate, interacting with the promoters of these genes through 3D contacts within the nucleus. How enhancers find their target genes remains largely elusive. Evolution offers a unique “natural perturbation experiment” to study the principles of enhancer-promoter communication. Enhancers, and especially the sequences spanning enhancer-promoter contacts, evolve faster than the gene expression patterns they control. This raises important questions about the genetic and epigenetic factors that sustain and drive the evolution of long-range gene regulation. To address these questions, my computational project will leverage an unpublished, high-resolution dataset on enhancer-promoter contacts from five mammalian species and three tissues, along with corresponding genomic sequences, enhancer annotations, and gene expression data. My analyses will: (1) map how enhancer-promoter contacts co-evolve with genomic sequences, chromatin states, and gene expression, (2) establish how large-scale genomic rearrangements disrupt or constrain these contacts, and (3) develop and train deep learning models to predict DNA sequences underpinning the evolution of enhancer-promoter contacts. By integrating functional genomics, evolutionary biology, and machine learning, this project will uncover the mechanisms behind the evolution of long-range gene regulation, with broad implications for understanding non-coding genetic variation in evolution, disease, and synthetic biology. The fellowship will enhance my expertise in comparative genomics, 3D chromatin biology, and deep learning, while fostering new collaborations and bringing evolutionary insights to the host lab.

Keywords: 3d chromatin architecture,enhancer promoter contacts,promoter capture hi c,gene regulation,machine learning,deep learning,evolutionary biology,comparative genomics
Recreating molecular memories: imaging the mechanics of chromosome assembly and the birth of cell identity (ChromoMemInMotion)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Molecules of Life: B iological  Mechanisms , Structures  and Functions
Panel description: For all organisms : Molecular biology , biochemistry, structural biology, molecular biophysics , synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1999575.0
EU funding (EUR): 1999575.0
Participants: 1
Project status: SIGNED

The gene expression patterns that define specific cell types are determined in part by epigenetic information encoded in histone marks that guide chromatin organization. During chromosome duplication, new histones lacking this information must be deposited to support the doubling of chromatin. However, the molecular mechanism of histone deposition and the coordination pathways that ensure epigenetic information is transmitted remain unknown. Determining the mechanics of chromosome assembly promises to open a new frontier in our understanding of the propagation of cell fate decisions that support multicellular life. Due to the antiparallel configuration of DNA, different DNA synthesis mechanisms are used on the daughter strands during DNA replication. How this is coordinated with the symmetric duplication of chromatin organization on daughter chromosomes is not known. I hypothesize that the replisome contains an extensive network of molecular wiring encoding the fundamental logic that governs histone transfer and deposition that is essential for the preservation of epigenetic cell identity and chromosome integrity. To discover this network, I propose a research program combining structural, biochemical, and single-molecule imaging approaches. To gain access to critical missing information, we will develop techniques that reveal the dynamics of histone transfer and deposition independently on each daughter strand in real-time for single replisomes. The proposed research will determine the structural basis of new histone deposition, reveal the dynamics of replication-coupled chromatin assembly, and address how epigenetic states are re-established on daughter chromosomes. Realizing these objectives will represent a major breakthrough in our understanding of the molecular mechanics of chromosome assembly, the transmission of epigenetic cell memory, and allow for transformative biomedical technologies through engineered reprogramming of epigenetic memories.

Keywords: dna replication,chromatin,single molecule
Biodiversity Building Blocks for policy (B3)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Innovation actions
Countries involved: Belgium,Denmark,Italy,Germany,Romania,South Africa,Bulgaria,France,Portugal
Call: Common European Green Deal data space to provide more accessible and exploitable environmental observation data in support of the European Green Deal priority actions (HORIZON-CL6-2021-GOVERNANCE-01, 2021)
Start date: 2023-03-01
End date: 2026-08-31
Duration (months): 42.0
Total project cost (EUR): 4853333.75
EU funding (EUR): 4778526.5
Participants: 14
Project status: SIGNED

The world is changing rapidly; climate change, land use change, pollution and natural resource exploitation are creating a global crisis for biodiversity whose magnitude and dynamics are hard to quantify. Decision makers at all levels need uptodate information from which to evaluate policy options. For this reason rapid, reliable, repeatable monitoring of biodiversity data is needed at all scales from local to global. Only by leveraging large volumes of data, advanced modelling techniques and powerful computing tools can we hope to synthesize these data within timescales that are relevant to policy. Data on biodiversity come from a diverse range of sources, citizen scientists, museums, herbaria and researchers are all major contributors, but increasingly new technologies are being deployed, such as automatic sensors, camera traps, eDNA and satellite tracking. Integrating these data is a major challenge, but is necessary if we are to create dependable information on biodiversity change. B3 will use the concept of data cubes to simplify and standardize access to biodiversity data using the Essential Biodiversity Variables framework. These cubes will be used, in conjunction with other environmental data and scenarios, as the basis for models and indicators of past, current and future biodiversity. The overarching goal of the project is to provide easy access to tools in a cloud computing environment, in real-time and on-demand, with state of the art prediction models of biodiversity, that will output models and indicators of biodiversity status and change. The project envisages a future where primary biodiversity data are seamlessly integrated into monitoring and forecasting such that policy and management can proactively respond to problems while at the same time reduce the costs of monitoring and management, and the negative impacts of biodiversity change.

Keywords: biodiversity,cloud computing,data cubes,essential biodiversity variables,indicators
Sustainable surface protection by glass-like hybrid and biomaterials coatings (BIO-SUSHY)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Belgium,Austria,France,Spain,Germany,Slovenia,Italy,United Kingdom
Call: Safe- and sustainable-by-design organic and hybrid coatings (RIA) (HORIZON-CL4-2022-RESILIENCE-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 4815296.25
EU funding (EUR): 4815296.25
Participants: 16
Project status: SIGNED

To meet EU key strategic orientations for the development of digital, enabling, and emerging technologies, sectors and value chains, the project BIO-SUSHY proposes a complete operating framework for the development of innovative repellent organic and hybrid coatings to challenge widespread yet polluting polyfluorinated alkyl substances. These coatings aiming both hydrophobic and oleophobic properties will be obtained from acknowledged processing technologies, i.e., bio-based thermoplastic powder and hybrid sol-gel. Advanced functionalization will be ensured by bio-based additives added to formulations. Coatings will be applied on various substrates for validation of applications at pre-industrial scale in different domains such as the textile, glass cosmetic and food packaging. Material selection, formulation and coating process will cope with a tailored regulating Safe and Sustainable by Design (SSbD) strategy which evaluating criteria will encompass the risk toxicity of materials and hazardous leachate as well as life cycle assessment to determine economic and environmental impacts along the value chains. This SSbD strategy will be powered by physics based and data driven modelling tools for predicting both repellent properties of coating surfaces and leaching mechanisms of composites. Along with experimental measurements, modelling activity will serve a larger computational tool including all data collection and curation in a harmonized and annotated infrastructure for training and provision towards existing data repositories and marketplaces. This tool will complete a wider dissemination and valorisation strategy including not only scientific and economic aspects, but also to pave the way towards certification of materials and products for their introduction in pre-standardization landscape. For all these valorisation aspects BIO-SUSHY will be assisted by stakeholders to ensure social acceptance and economic impact of the foreseen innovations in coatings.

Keywords: ssbd pfas free bio based water and oil repellent textile,food packaging,cosmetics qsar read across molecular modelling data repositories toxicology standardization
HydrogEn Lightweight & Innovative tank for zerO-emisSion aircraft (H2ELIOS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Aviation
Action type: Innovation actions
Partnership: CLEAN-AVIATION (JU-JTI)
Countries involved: Spain,Greece,Belgium,Italy,Slovenia,Austria,Germany,Norway
Call: Large Scale Lightweight Liquid Hydrogen Integral Storage Solutions (HORIZON-JU-Clean-Aviation-2022-01, 2022)
Start date: 2023-01-01
End date: 2026-07-31
Duration (months): 43.0
Total project cost (EUR): 12069406.75
EU funding (EUR): 9959306.89
Participants: 18
Project status: SIGNED

To enable a technologically and economically feasible H2-powered aviation, new integral LH2 tank solutions are required that could serve as part of the airframe main structure and capable of withstanding its respective loads. The H2ELIOS project will develop an innovative and effective lightweight LH2 storage system for aircraft. It will be implemented as demonstrators in two fuselage-like cylinder section with approximately 1.9 m of external diameter and approximately 2.3 m of external length. These demonstrators would be duly supported by component and subsystem ground tests at appropriate scale at project completion (TRL 5 at storage level). The aim is that the concept is ready to be embedded and integrated in a specified aircraft architecture for flight demonstration in later stages. H2ELIOS will provide a feasible and novel low-pressure double-layer composite tank-based system, enabling the tank shape to be either conformal or non-conformal to the profile of the aircraft. Its general effectiveness will be assessed in terms of high GI performance and easiness of integration within the aircraft structure. This concept will be supported by latest evolutions of innovative methods and technologies in terms of multidisciplinary design development, manufacturing processes and means of compliance and shall be demonstrated in operational conditions: first on ground up to TRL5 and then in flight by the end of Clean Aviation Phase 2 clearing a TRL6 maturation gate. Finally, delivery to the market is expected in the 2030-2035 period. In this way this project shall contribute to accomplish the objectives of the European Green Deal regarding decarbonization of the aviation industry. The activities of H2ELIOS will be supported by explicit agreed support of EASA and an External Advisory Board comprising commercial aircraft OEMs, H2 management and cryogenics experts, MRO services, airlines, aircraft system integrators, materials developers and suppliers and airports operation

Keywords: lh2,cyrogenics,integral and conformal non conformal tank,insulation,h2 management,shm,leak detection,testing,digital twins,sustainability,lcca,cradle to cradle lca,lightweight aircraft
Copernicus Foundation Models for a Thinking Earth (ThinkingEarth)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: EU Space
Destination: EU Space
Action type: Research and Innovation actions
Countries involved: Greece,Spain,Germany,Belgium,Austria,Italy,France
Call: Large-scale Copernicus data uptake with AI and HPC (HORIZON-EUSPA-2022-SPACE, 2022)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 2999875.0
EU funding (EUR): 2999875.0
Participants: 13
Project status: SIGNED

At ThinkingEarth, we view the Earth as a complex unified and interconnected system. To harness the power of Artificial Intelligence (AI), we use cutting-edge techniques, including deep learning, causality, eXplainable AI, and physics-aware Machine Learning. We leverage the predictive abilities of Self-Supervised Learning and Graph Neural Networks to develop task-agnostic Copernicus Foundation Models and a Graph representation model of the Earth. We demonstrate the potential of these assets through small-scale downstream Spotlight Applications, as well as large-scale use cases that integrate distributed industrial and user non-EO datasets. These use cases address ambitious problems with high socio-environmental impact and new business growth opportunities, such as accelerating Europe's clean energy transition and independence from volatile fossil fuels, understanding Earth's processes by modeling causal Earth system teleconnections, and assessing and modeling the impact of current and future Climate emergency in biodiversity and food security.

Keywords: foundation models,ai4eo,deep learning,causality,