Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Intimate Dispossession: The Afterlives of Plundered Jewish Personal Possessions in the Aftermath of the Holocaust (PLUNDERED LIVES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-04-01
End date: 2029-03-31
Duration (months): 60.0
Total project cost (EUR): 1999888.0
EU funding (EUR): 1999888.0
Participants: 1
Project status: SIGNED

This project aims to write the history of the great plunder of small things—everyday household objects, and personal items, including clothing, looted on a mass-scale by local non-Jews during, and in the aftermath of, the Holocaust. While historical research has focused on the top-down and centralized Nazi state’s takeover of Jewish financial assets, real estate, businesses, or art objects, we know nothing about the afterlives of unmarked objects of daily use that changed hands in the course of the Holocaust and continued being used for decades in the small local communities of East-Central Europe. The main objectives of the project are to document different modes of how Jewish personal possessions were appropriated by non-Jewish local populations of East-Central European shtetls; examine how they have been redeployed, adapted, and misused by their new owners; and assess the social and psychological trans-generational impact of this kind of plunder on the communities of both the beneficiaries and the victims. Breaking with the top-down view on Holocaust dispossession, this project focuses on eight microstudies of communities located in three different administrative units of German-occupied East-Central Europe. PLUNDERED LIVES’ novelty is in a combination of a microhistorical analysis with qualitative approaches of social studies and social psychology; extending the typical time frame (1939-1945) to include dispossession practices that continued after WWII; and experimental outreach strategies of digital crowdsourcing, curatorial interventions in public spaces, and cross-generational interviewing to elicit responses from the implicated communities and document hitherto inaccessible material in private possession. Highly interdisciplinary, PLUNDERED LIVES will open avenues for future research into the fields of genocide studies, anthropology of conflict, social psychology, economic history and forensic studies.

Keywords: holocaust history,genocidal dispossession,east central europe
Geometry, Control and Genericity for Partial Differential Equations (GEOEDP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: France
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-10-01
End date: 2028-09-30
Duration (months): 60.0
Total project cost (EUR): 1647938.0
EU funding (EUR): 1647938.0
Participants: 1
Project status: SIGNED

Many physics models are described by waves or more generally dispersive equations (Schrödinger equations) with propagation in a non homogeneous and bounded medium. Toy models (mostly in flat backgrounds) have been developed by mathematicians. However, many questions remain open even on these simplified models in the presence of inhomogeneities and boundaries. In particular, the works of mathematicians in the last decade have allowed to exhibit some pathological behaviours which appear to be quite unstable. A first point in this proposal will be to expand the understanding of the influence of the geometry (inhomogeneities of the media, boundaries) on the behaviour of solutions to dispersive PDE’s. When these behaviours appear to be unstable, a natural question is whether they are actually rare. The last years have seen the emergence of a new point of view on these questions: random data Cauchy theories. The idea behind is that for random initial data, the solution’s behaviours are better than expected (deterministically). The second point of this project is precisely to go further in this direction. After identifying these pathological behaviours, is it possible to show that for almost all initial data, almost all geometries, they do not happen? Understanding how to combine the powerful techniques from micro-local and harmonic analysis with a probabilistic approach in this context should allow a much better understanding of these physically relevant models. Summarising, the purpose of my project is to develop tools and give answers to the following questions in the context of dispersive PDE’s (and to some extent fluids mechanics) Can we understand the influence of the geometric background (and boundaries) on concentration properties and the the behaviour of solutions to dispersive evolution PDE’s? Can we define generic behaviours for solutions to waves and fluids PDE's ? Can we show that some very pathological behaviours (which do happen) are actually very rare?

Keywords: partial differential equations,control,scattering,probabilities
Assessing long-term trends in the vegetation of European habitats and evaluating the effectiveness of protected areas (VegTrends)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Czechia
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-02, 2022)
Start date: 2022-10-17
End date: 2024-10-16
Duration (months): 24.0
Total project cost (EUR): 150438.72
EU funding (EUR): 150438.72
Participants: 1
Project status: CLOSED

Across most of the globe, ecosystems are being transformed, degraded and fragmented. In Europe, more than 30% of terrestrial habitats have been assessed as "threatened", and the extent to which existing protected areas effectively safeguard biodiversity is currently debated. Halting biodiversity loss, ensuring current and future provisioning of its associated benefits, and protecting natural habitats are core priorities of worldwide conservation agendas, e.g. the UN Sustainable Development Goals or the EU 2030 Biodiversity Strategy. To achieve these goals, assessments of biodiversity changes through time are essential, especially if accounting for multiple diversity facets and for different levels of biological organization. Resurvey studies of vegetation, based on the re-sampling of historically surveyed vegetation plots, are increasingly used as a cost-effective means to detect temporal changes across many ecosystems. The recent availability of long-term vegetation datasets spanning across large geographical areas and multiple ecosystems offers an unprecedented opportunity to quantify biodiversity change efficiently and across previously intractable spatial extents. In light of these considerations, VegTrends aim to: i) provide a multi-habitat assessment of non-random temporal vegetation changes accounting for multiple diversity facets (taxonomic, functional, phylogenetic) and different biological levels (community and species); ii) evaluate the effectiveness of protected areas in conserving European habitats. To address these aspects, VegTrends will make use of ReSurveyEurope, a unique database of long-term vegetation time-series derived from resurvey studies. Together with a novel and comprehensive methodological approach, this will allow gaining unique insights into the temporal trends in European vegetation and assessing risks for individual habitats.

Keywords: temporal changes resurvey long term data vegetation biodiversity natural habitat europe
Inositol pyrophosphates in phosphate homeostasis: increasing nutrition value in rice (P-use efficient rice)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-11-10
End date: 2025-11-09
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: SIGNED

Phosphorus (P) is one of the most important molecules having a role in almost every aspect of plant metabolism. So, a constant supply of P and its efficient use as Pi are necessary to sustain plant growth, development and yield. However, in most of the agricultural lands, Pi is poorly available to plants. In order to overcome the consequences of Pi deficiency, farmers have adopted excessive and routine application of P fertilizers, causing serious impacts on the environment. There are two main concerns regarding the excessive use of P fertilizers. On one hand, erosion by water and wind results in P runoff into open water bodies, causing a major threat to planetary health. On the other hand, P deposits represent a limited resource on our planet. Additionally, some P forms within the plant (such as phytate) are crucial to determine micronutrient availability for the human nutrition and animal feed. Therefore, there is an urgent need to understand the functional aspects of Pi sensing, transport, signaling and remobilization, and, thus, it is imperative to develop crops with enhanced PUE (P Use Efficiency) and micronutrient availability to support a more sustainable agriculture system. Although rice counts for the third-most produced cereal crop in the world, it is limited to have only 25% PUE, providing an enormous scope for improvement in P nutrition. In this line, we propose to investigate the synthesis and physiological roles of inositol pyrophosphates (PP-InsPs) in Pi signaling and homeostasis to improve the nutritional value of rice. The proposed research will help to better understand how PP-InsPs control PUE, and will provide the knowledge to reduce phytate content in rice seeds, thereby increasing micronutrient bioavailability without compromising plant immunity, health and yield. In short, the discoveries will help to enhance PUE, preserve P-deposits, mitigate the detrimental consequences of excessive P-fertilization and improve the nutritional value of rice.

Keywords: rice,phosphorus,phosphorus use efficiency,inositol pyrophosphates,phytate,hidden hunger,plant and human nutrition,crop yield,gene editing
IRB Barcelona International PhD Programme: Driving talent towards professional excellence and high impact biomedicine. (IRB-DRIVE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Spain,Italy,Denmark,Germany
Call: MSCA COFUND 2024 (HORIZON-MSCA-2024-COFUND-01, 2024)
Start date: 2026-09-01
End date: 2031-08-31
Duration (months): 60.0
Total project cost (EUR): 1584000.0
EU funding (EUR): 1584000.0
Participants: 15
Project status: SIGNED

IRB-DRIVE has been conceived to attract high-capacity talent to IRB Barcelona (IRB) and train, upskill and equip them towards impactful professional careers in biomedicine through a comprehensive doctoral programme. IRB is an independent, non-profit research center engaged in fundamental and applied biomedical science whose widespread recognition for research excellence is complemented and supported by a renowned international PhD programme which has accumulated numerous qualitative improvements over the recent years, thanks in part to the implementation of 2 MSCA-COFUND programmes - IRB-DREAM and IRB-TARGET. IRB-DRIVE will offer 10 four-year fellowships through 2 calls to exceptional doctoral candidates informed via an extensive dissemination campaign and awarded after a fair and transparent selection and recruitment process that builds on institutional best practices endorsed by the HR Excellence in Research Award (held by the institute since 2014). IRB-DRIVE fellows will conduct their research projects in one of IRB’s 29 research groups among the institute´s 6 interdisciplinary research nodes and will have access to a broad range of international and intersectoral collaboration and mobility opportunities strengthened by the programme’s network of associated partners. Apart from promoting their technical and transferable skills, IRB-DRIVE will facilitate their readiness to rewarding roles in research through a novel career-driven itinerary. Finally, by implementing a holistic support programme that includes a novel mentoring agenda and nurtures their well-being through meaningful interventions, IRB hopes to drive these future leaders of biomedicine to research and professional success.

Keywords: doctoral training,personalized career development,biomedicine,translational research,research excellence,3i dimension,innovation,societal impact,wellbeing,mental health,entrepreneurship
Biomimetic Cornea fabrication by 3D printing and adult Mesenchymal Stem Cell directed differentiation. (MIMECOR)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-11-30
Duration (months): 30.0
Total project cost (EUR): 262393.2
EU funding (EUR): 262393.2
Participants: 3
Project status: SIGNED

MIMECOR aims to develop an artificial and biomimetic cornea to achieve a major improvement in the quality of life of corneal disease patients, reducing their dependence on corneal transplants. This will be reached through the preparation and further modifications of a human-like cornea through the combination of additive manufacturing, stem cell transdifferentiation, and colonisation as an alternative to natural cornea donation. This approach is going to be a major breakthrough in Ophthalmology, as it will overcome the existing limitations of current treatments: it could become a reference in the therapy for specific corneal pathologies. The candidate researcher, Dr. Marć will provide to the project with her broad experience in applied preclinical research, gained in academic and industrial research groups of different European countries. She will learn cutting-edge techniques in Regenerative Medicine applied to Ophthalmology, through the interaction with a multidisciplinary, collaborative, and creative environment with specialists in engineering, medicine, physics, biology, and biochemistry. The candidate will perfect research skills such as experimental design, scientific writing, open science and data analysis. Moreover, through diverse training activities and a non-academic placement at a small-medium enterprise (the largest monographic ophthalmological private hospital in Europe), Dr. Marć will also acquire transferable skills and experience in grant implementation, ethics in Responsible Research and Innovation, time management, and scientific communication and divulgation. Besides, this formative plan accommodates her needs with the capabilities of the hosting group and institution. All this knowledge and skills will be crucial for the career success of the researcher. Due to her knowledge of the local language, Dr. Marć intends to become an established biomedical scientist in Spain after MSCA-PF, applying for Spanish postdoctoral grants and positions.

Keywords: cornea,3d printing,biocompatibility,keratoconus
Multi-metal anode: Towards safe and energy dense batteries (MULTIMETALBAT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Spain
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 1889561.0
EU funding (EUR): 1889561.0
Participants: 1
Project status: SIGNED

Li metal is considered to be the holy grail anode material due to its high specific capacity and low standard redox potential and could, in theory, lead to the assembly of extremely high energy density cells. Metal anode based batteries, in general, represent the main viable option towards a leapfrog in terms of energy density when compared with current Li-ion technology, thus motivating important research efforts in Li-air, Li-Sulfur and, more recently, solid state batteries (SSB). Unfortunately, all of these technologies (even SSB) suffer from dendritic Li growth, eventually resulting in short circuit/thermal runaway. Requirements for smooth Li metal electrodeposition, mostly consist in the fine control of the cation mass transport through the solid electrolyte interphase (SEI), which in turn is governed by the composition, morphology and stability of the latter. Unfortunately, and after several decades of investigation, it is virtually impossible to achieve the perfect interphase/interface which can sustain thousands of cycles in real battery operation conditions. The main objective of MULTIMETALBAT is to bring a new paradigm for metal anode by developing electrolytes containing a mixture of multiple cations (Li+, Na+, K+, Ca2+ or Mg2+) which will modify the overall thermodynamics of plating and stripping when compared with conventional single metal anode. Kinetic competition between various electrodeposition processes will be promoted and the SEI will be engineered to sustain high mechanical, chemical and thermal stability, hence helping promoting homogeneous cation diffusion through it. Targeted figures of merit include: i) critical current density for 3D metal growth above 10 mA.cm-2 and ii) 350 Wh/kg energy density for 100 mAh pouch cells, almost doubling that of current Li-ion. Yet, the main objective of MULTIMETALBAT will be increased safety and extensive standard safety measurements will be performed on prototype cells and compared with Li-ion batteries.

Keywords: energy storage,battery,metal anode
Understanding of the Membrane Connection Linking the Nucleus to the Endoplasmic Reticulum (conNEctoER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Cell Biology, Development, Stem Cells and R egeneration
Panel description: For all organisms : Structure and function of the cell, cell -cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Austria
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-04-01
End date: 2029-03-31
Duration (months): 60.0
Total project cost (EUR): 1995843.0
EU funding (EUR): 1995843.0
Participants: 1
Project status: SIGNED

Compartmentalization into membrane-bound organelles is a key feature of all eukaryotic cells, and communication between organelles needs to be tightly controlled. A key organelle for the inter-organelle communication is the endoplasmic reticulum (ER), which is the major site of lipid and membrane protein synthesis. The ER exchanges molecules by forming stable contact sites with multiple organelles such as mitochondria via specific tethering proteins and transporters. In contrast to these contact sites, the ER is linked to the nucleus via direct fusion to the outer nuclear membrane of the nuclear envelope (NE). These ER-NE junctions are essential for supplying the lipids and proteins that are synthesized in the ER to the NE. Hence, nuclear function and morphology depend on the proper communication via ER-NE junctions. However, the biogenesis, architecture and maintenance of ER-NE junctions have remained elusive. We have recently found that ER-NE junctions exhibit a narrow and constricted ultrastructure during the cell cycle in mammalian cells. These observations led us to postulate that ER-NE junctions are formed and maintained by specific membrane-shaping proteins that are crucial for nuclear function. Here, we propose to identify the molecular mechanism that governs the structure and function of ER-NE junctions. We will provide a quantitative and dynamic high-resolution view of these enigmatic structures by combining time-resolved electron microscopy and quantitative live imaging with molecular perturbations. Using these datasets, we aim to develop a mechanistic model of how ER-NE junctions form and contribute to nuclear function. The NE proteins supplied via ER-NE junctions have critical roles in gene expression, nuclear organization, and nuclear pore biogenesis, as well as in differentiation, development, and disease. Therefore, our research will provide a new conceptual framework that will open lines of investigation in many fields beyond ER/NE biology.

Keywords: correlative microscopy quantitative imaging nuclear envelope nuclear pore complex electron tomography