Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Quantifying landslide activity and contribution to sediment fluxes with cosmogenic radionuclides and grain-size distributions (LandFlux)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2020-05-31
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

Landslides are a primary erosion process in steep landscapes and are among our most deadly and damaging geohazards. However, it is extremely difficult to constrain long-term or past rates of landslide activity, which prevents accurate predictions of their activity in the face of climate change. This project aims to develop and apply a new methodology to quantify long-term landslide activity and contribution to sediment fluxes. To achieve this goal, I will integrate two growing research lines that have identified signatures of landslide activity: grain-size distributions and cosmogenic radionuclide (CRN) concentrations, which I will integrate in a numerical model. We will exploit, for the first time to our knowledge, the differences in depth production profiles between CRNs (14C and 10Be), using the 14C/10Be ratio to infer erosional depth-provenance and track erosional processes. We will sample grain-size distributions, and 14C and 10Be concentrations across different grain sizes, in landslide deposits and river sediments within catchments with excellent published constraints on landslide activity in Italy and New Zealand. We will develop a new Matlab numerical model, which will be calibrated using our new data, to determine landslide rates and fluxes using CRN and grain-size data, hence creating a tool that can be used to predict long-term or past landslide activity in other areas where good constraints are not available. This project has the potential to expand the uses of CRNs to include erosional depth-provenance. Furthermore, being able to infer long-term and past landslide rates would be a major step forward in how we tackle landscape evolution and landslide hazards. This project will be developed at the GFZ Potsdam (host) and ETH Zurich (secondment), bringing together outstanding infrastructures and researchers, and offering the best possible environment for my training and networking, which will in turn enhance my future career opportunities.

Keywords: landslides,cosmogenic radionuclides,grain size distributions,sediment flux,numerical modeling,erosion processes,landscape evolution
WoodJam—Sediment dynamics of instream wood jams and managed installations (WoodJam)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-08-27
End date: 2020-08-26
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Natural flood management practices, including engineered logjam installations, can slow floodwaters in upstream catchments, promoting infiltration and reducing flood severity. In order to reduce flood damages and prepare for an expected increase in severe floods due to climate change, the EU Water Framework Directive encourages the use of engineered logjams and other natural flood management interventions. It is necessary to consider the effects of channel-spanning engineered log jam installations, which are the most common, on stream hydrodynamics and sediment scour and retention in order to guide management interventions and accurately assess the implications of natural flood management projects. The proposed project objectives will fill existing knowledge gaps related to the quantification of logjam-induced sediment storage and flow resistance, in addition to the prediction of the length over which an engineered logjam influences the downstream river channel. WoodJam will experimentally investigate the impact of jam geometry and spacing on sediment storage and develop a method to assess the porosity of a jam without disassembly. Experimental studies conducted in sediment flumes at Cardiff University will be related to observations of existing natural flood management projects in the UK and Germany, with design and management recommendations transferred to environmental resource managers through discussion and policy documents. Hydraulic modelling studies will identify methods to represent common engineered logjam designs in 2D flood modelling tools, validated by experimental results. These methods will enable accurate modelling of natural flood management project effects. The project approach will provide an innovative approach by uniting CU expertise in LW hydraulics and modelling with Dr. Follett’s previous experience investigating flow and sediment transport through porous obstructions (Professor Heidi Nepf, MIT).
Earth Observation freshwater monitoring services (eoFRESH)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: SME instrument
Countries involved: Germany
Call: SME Instrument (H2020-SMEINST-1-2015, 2015)
Start date: 2016-03-01
End date: 2016-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Water is increasingly recognized as the most relevant resource of the 21th century, and UN Water recommends in sustainable water investments to prevent future conflicts. Significant social and economical impacts are associated with changes of water quality in inland waters. It is almost impossible to think, in the 21st Century, that water industries and governments would produce sustainable economic and ecological development plans on water without reasonable information on hand. Accordingly, an increasing demand from water industries, including aquaculture, water construction or dam operators, insurers, development banks and water agencies on actual or long-term historic water related information is observed. The eoFRESH service responds to the increasing demand with an independent multi-satellite based monitoring solution, as only traditional in-situ methodologies are capable neither to retrieve historic information, nor to provide actual harmonized information for a huge number of inland waters. eoFRESH combines the monitoring capabilities of an increasing number of historic, actual and future satellite missions, allowing nowadays up to daily global observations and going back in time for 30 years for millions of water bodies and rivers globally. eoFRESH starts with the provision of relevant globally harmonized water quality measures (e.g. turbidity and related suspended matter, phytoplankton concentration). The service is characterised by three key features: Independency with globally harmonized and valid and consistent measures, extremely cost-efficiency through fully automated production on free accessible satellite missions, extremely easy information uptake through access from web-services and applications. Within the Phase 1 feasibility study it is the core intention to summarize all the necessary information, including technical and economic aspects which are relevant to provide a sound roadmap to bring the eoFRESH service to the market.

Keywords: water quality,web application,copernicus
Engineering the Biointerface of Nanowires to Direct Stem Cell Differentiation (EnBioN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-02-01
End date: 2023-07-31
Duration (months): 66.0
Total project cost (EUR): 1495430.0
EU funding (EUR): 1495430.0
Participants: 1
Project status: SIGNED

ENBION will engineer a platform to direct the differentiation of stem cells by developing principles for the rational design of the biointerface of nanowires. It is increasingly evident that efficient tissue regeneration can only ensue from combining the regenerative potential of stem cells with regulatory stimuli from gene therapy and niche engineering. Yet, despite significant advances towards integrating these technologies, the necessary degree of control over cell fate remains elusive. Vertical arrays of high aspect ratio nanostructures (nanowires) are rapidly emerging as promising tools to direct cell fate. Thanks to their unique biointerface, nanowires enable gene delivery, intracellular sensing, and direct stimulation of signalling pathways, achieving dynamic manipulation of cells and their environment. This broad manipulation potential highlights the importance and timeliness of engineering nanowires for regenerative medicine. However, developing a nanowire platform to direct stem cell fate requires design principles based on the largely unknown biological processes governing their interaction with cells. Enabling localized, vector-free gene therapy through efficient transfection relies on understanding the still debated mechanisms by which nanowires induce membrane permeability. Directing cell reprogramming requires understanding the largely unexplored mechanosensory processes and the resulting epigenetic effects arising from the direct interaction of nanowires with multiple organelles within the cell. Engineering the cell microenvironment requires yet undeveloped strategies to localize signalling and transfection with a resolution comparable to the lengthscale of cells. ENBION will develop this critical knowledge and integrate it into guidelines for dynamic manipulation of cells. Beyond the nanowire platform, the principles highlighted by this unique interface can guide the development of nanomaterials with improved control over cellular processes.

Keywords: nanowires,regenerative medicine,biointerface,nanotopography,gene therapy,mechanotransduction,epigenetics,patterning,porous silicon
AdamFrame: A Low-cost, High-performance, Software guided Quadrilateral Octopod External Fixator (AdamFrame)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Türkiye
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-02-01
End date: 2018-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

“AdamFrame” is a high performance, software guided, low cost, fully-assembled quadrilateral octopod “external fixator” to treat complex orthopedic trauma and bone deformities, minimizing physician’s & implicit biases and maximizing patient’s comfort and mobility during the treatment, in the most resource efficient way; by ensuring less hospital follow-up visits and less modifications/reoperations. Adam Frame provides a complete product and system which integrates all the advantages of the previous models into a new design. External fixators (Ex-Fix) are the medical devices that are used for externally bone fixations. External fixation is the surgical treatment used to stabilization of bone and soft tissue(flexion contracture etc.), bony deformity correction at a distance from the operative or injury focus. They provide unobstructed access to the relevant skeletal and soft tissue structures for their initial assessment and also for secondary interventions needed to restore bony continuity and a functional soft tissue cover. External fixation is mostly applied to congenital (Innate) bone deformities(both primary and secondary deformities that are, non-union, mal-union, pseduarthrosis etc.) and trauma caused bone fractures. Both bone deformity and bone fractures (with many broken bone fractures) treatments are long lasting (up to 12 months) treatments and these treatments need follow-ups and modifications during the healing period.

Keywords: external fixator,orthopedics,bone fixation,limb lengthting
The world’s first “Plug-in and Use-Solar PV with Storage”, designed for small city apartments in the EU. (SolMate)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Austria
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2020-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Efficient Energy Technology GmbH (EET) is a spin-off of Graz University of Technology, Austria, founded in May 2017. The founding team consists of three members, Dr. Christoph Grimmer (CEO), DI Stephan Weinberger (CTO), DI Florian Gebetsroither (COO/CFO), currently employing 12 additional people. Two strategic investors joined the company in 2017 (500kEUR investment). A strategic manufacturing partner have also been identified. The core innovation of EET is the patented, non-invasive measurement technology “NetDetection”, a high frequency measurement, that allows the smart utilization of photovoltaic (PV) power without any hardware installation and costs. A first working prototype, called “SolMate”, which exceed TRL6 already, has been developed and is presently being tested in 30 real life installations in city apartments. Feedback from these 30 field installations is being collected (both technical and customer satisfaction), analysed and will be implemented in the version of SolMate which will be placed in the market in near future. The main customer benefits and USPs of SolMate are the user friendliness (unique and simple plug-in-and-play PV system including energy storage) as well as the unmatched price (30% cheaper than any closest competitor product in market; customers will save €100-300/year electricity costs by using SolMate). Further advantages over state-of-the-art systems include small system size (designed for city apartments) and smart power control through EU-patented technology. CO2 savings are 93% compared to average electricity mix.

Keywords: photovoltaics for self installation,plug in photovoltaics
Transforming ReseArch & INnovation agendas and support in 4EU+ (TRAIN4EU)

Framework: Horizon 2020 — Science with and for Society
Action type: Coordination and support actions
Countries involved: Germany,Italy,Poland,France,Czechia,Denmark
Call: Support for the Research and Innovation Dimension of European Universities (Part I) (H2020-IBA-SwafS-Support-1-2020, 2020)
Start date: 2021-01-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 2000772.65
EU funding (EUR): 2000772.65
Participants: 6
Project status: SIGNED

TRAIN4EU+ is rooted in the 4EU+ alliance’s ambition to strive for excellence in all aspects of our roles as comprehensive, public research-based and excellence focused European universities. Specifically, this proposal will be a transforming effort in our ongoing work to improve and expand how we i) support our researchers as they continue to expand the limits of knowledge and ii) ensure that this knowledge helps society address the challenges of our times. We will do this by pursuing five objectives. These are: i) We will find new ways to improve - individually and collectively – our support structures for enhancing quality and impact of R&I; ii) We will foster a culture of co-learning and co-innovation across the consortium based on a thorough best-practice assessment; iii) We will pilot selected transformative measures within different modules within the project life time; iv) We will push boundaries by pinpointing and highlighting drivers and facilitators of, as well as barriers and obstacles, to transformative change, v) We will strive to scale up impact, in collaboration with other alliances, and through dissemination and communication to all stakeholders, including targeted events for policy makers, to ensure wide uptake and exploitation of results. To pursue these objectives, we rely on a systematic methodology to uncover best practises and lessons learned across R&I support functions, to stakeholder involvement, and to share and co-develop innovations and ideas for transformative action across all six universities in 4EU+. We implement this methodology in a concerted effort s across our six core work packages that each relate to the relevant transformation modules. An ambitious dissemination and outreach effort will ensure our learnings are made available for policy makers, fellow universities, civil society, business and other stakeholders; thus providing invaluable input to the ongoing effort of preparing the European universities for the future.

Keywords: research strategy,linking academia business citizens,open science,university governance,university policy,research infrastructure sharing,human capital
Specific Fluorogenic Peptides for Imaging Metastasis-associated Macrophages (MACROIMAGING)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-01
End date: 2017-09-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

MACROIMAGING is a highly interdisciplinary project encompassing the preparation and optimisation of innovative fluorogenic imaging tools with high selectivity for metastasis-associated macrophages. The metastatic potential of tumours is defined by the tumour microenvironment (TM), where macrophages are the most abundant cells. However, the role of macrophages in the TM remains elusive mainly because of the lack of technologies to target these unique populations of cells in vivo. CD11b+ metastasis-associated macrophages are recruited by metastasing cancer cells. Their depletion reduces the number and size of metastasis, suggesting that their recruitment is essential for persistent growth of cancer cells. However, there is a need for imaging tools that report the localisation and cell fate of these macrophages to understand how they help tumour cells to progress in the TM. By means of Dynamic Combinatorial Chemistry, libraries of cyclic peptides will be generated from individual tetrapeptides through reversible disulfide bonds. Governed by thermodynamics, DCC will amplify cyclic peptides showing high affinity for CD11b+ macrophage receptors, involved in the development of metastasis. This technique will supply specific cyclic peptides targeting CD11b. Click chemistry (i.e. CuAAC) will allow the conjugation of these peptides to macrophage-specific fluorophores to generate FLUOROMACS. FLUOROMACS will enable selective imaging of CD11b+ macrophages by means of receptor-mediated endocytosis. Selectivity will be confirmed in vitro using macrophages from normal cohorts and knockouts. Finally Fluoromacs will be optimised as in vivo imaging probes for metastasis-associated macrophages. In a nutshell, MACROIMAGING will provide the first generation of chemical probes for imaging metastasis-associated macrophages in vivo. This methodology will also have enormous impact in other areas of chemical biology, such as protein recognition, drug discovery and theranostics.

Keywords: imaging tumour microenvironment metastasis dynamic combinatorial chemistry fluorogenic probes cyclic peptides
Sustainable Mixed-ion Layered Perovskite Solar Cells (MPerS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-04-01
End date: 2017-03-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

We propose to create and investigate new types of organic-inorganic perovskite materials for low-cost solar cells. The state-of-the-art perovskite based solar cells employ MAPbI3, which has raised concerns over the potential toxicity of Pb. The strategy of the MPerS project is to create, investigate and optimise sustainable perovskite materials for solar cell application. More than one types of metal and organic ions will be introduced in the perovskite structure to realize layered materials which are expected to exhibit both excitonic and free carrier behavior with enhanced stability. Thin films of the new materials will be characterized using several techniques, e.g. Xray diffraction. THz, Time resolved emission spectroscopies, EBIC will be used to understand the generation and dynamics of charge carriers in the materials and across interfaces. Development of solar cells will be carried out with an aim to reach 15% power conversion efficiency employing a non-toxic absorber. This highly interdisciplinary project that spans the field of chemistry, condensed matter physics, electronics and engineering is conceived on basis of the combined expertise of the host and the applicant and state-of-the-art infrastructure at the UOXF. A secondment at Oxford PV will test the commercial viability of the project. This project addresses Horizon 2020’s goals on clean and sustainable energy and the EU’s concern on toxicology of Pb . Completion of the project will open up new areas in low-cost electronic materials with wider impact and improve EU’s competitiveness in materials research. While the applicant will get an opportunity to learn new experimental skills in condensed matter physics and spectroscopy and benefit from industrial exposure. UOXF will benefit from the applicant by using his skills and broader broader collaboration with leading researchers in materials science. A plan is also proposed to carry out public engagement, dissemination and commercial exploitation.

Keywords: perovskite,sustainble lowcost solar cell