Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
ROBUSTIFYING GENERATIVE AI THROUGH HUMAN-CENTRIC INTEGRATION OF NEURAL AND SYMBOLIC METHODS (ROBUSTIFAI)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: A human-centred and ethical development of digital and industrial technologies
Action type: Research and Innovation actions
Partnership: AI-DATA-ROBOTICS (co-programmed)
Countries involved: United Kingdom,France,Austria,Sweden,Israel,Czechia,Belgium,Ireland,Germany,Norway,Switzerland
Call: Explainable and Robust AI (AI Data and Robotics Partnership) (RIA) (HORIZON-CL4-2024-HUMAN-03, 2024)
Start date: 2025-06-01
End date: 2028-05-31
Duration (months): 36.0
Total project cost (EUR): 7362490.0
EU funding (EUR): 7362490.0
Participants: 19
Project status: SIGNED

Generative AI (GenAI), such as foundation models, represents a powerful and transformative class of AI capable of learning patterns from data and generating new content. However, GenAI has notable shortcomings that can lead to misuse or hinder its widespread adoption and positive societal and economic impact. These shortcomings stem from its lack of robustness in three key areas: technical, operational, and user robustness. Addressing these challenges in foundation models, especially in the context of human cyber-physical systems (HCPS)—the most demanding GenAI applications in terms of robustness—will pave the way for solutions applicable across various domains, unlocking GenAI's full potential.Building on the EU’s competitiveness in constructing and assuring dependable complex systems, RobustifAI, a 3-year project with a budget around €9M, brings together 18 leading partners spread over 10 EU countries but also Switzerland and India, to tackle the above three-dimensional robustness challenge in GenAI systems. We aim to make a step change to the existing GenAI system development paradigm by developing and promoting a rigorous design and deployment methodology for building robust GenAI systems. The methodology is based on the following three orthogonal innovative axes: (1) techniques to understand, express, and embed human-centric needs within the neural model, (2) principled methods for integrating neural models and symbolic techniques, and (3) enabling the adaptivity of GenAI systems to environmental changes and user variations. RobustifAI will actively contribute to on-going EU initiatives on AI, such as the AI-BOOST project on AI challenges and other EU projects on AI efficiency, autonomous vehicles, or service robots. Its successful execution will secure for the EU a distinct and leading position in more sustainable and socially beneficial AI advancements, and strengthen EU’s vision that technical advances and societal benefits can be achieved simultaneously.

Keywords: generative ai,robustness,human centric integration,ai verification and validation,ai runtime monitoring,testing of autonomous driving systems,llm powered service robots
European iNitiative for Low cost, Innovative and Green High Thrust ENgine - Engine Demonstration (ENLIGHTEN-ED)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Space
Destination: Open Strategic Autonomy in Developing, Deploying and Using Global Space-Based Infrastructures, Services, Applications and Data
Action type: Research and Innovation actions
Countries involved: France,Germany,Belgium,Italy,Austria,Netherlands
Call: Low cost high thrust propulsion for European strategic space launchers - technologies maturation including ground system tests (HORIZON-CL4-2023-SPACE-01, 2023)
Start date: 2024-03-01
End date: 2027-02-28
Duration (months): 36.0
Total project cost (EUR): 20307271.25
EU funding (EUR): 19965202.75
Participants: 15
Project status: SIGNED

The space sector is a source of economic growth, jobs and exports, contributing to all Key Strategic Orientations of the EU strategic plan. Faced with growing competition and technological disruption, it is drastically vital to act in support of European space launchers development to preserve European independent access to space. European launchers must improve their competitiveness by halving launch price in the short term. In the long term, Europe will create common building blocks for an integrated and competitive European family of launchers of all scales with reusability functionalities. The purpose of ENLIGHTEN is to develop and test advanced production means and technologies for reusable rocket engines, following on the Prometheus® ESA program, in order to create a family of reusable, high-power engines fueled by bio-methane or green hydrogen. In the continuity of ENLIGHTEN, ENLIGHTEN-ED aims at maturate enabling technologies, subsystems, tools and processes by bringing them to TRL5/6. Then, ENLIGHTEN-ED will demonstrate the above technologies by engine on-ground demonstration tests by 2026 to reach TRL7. In the frame of ENLIGHTEN-ED, a tailored consortium (including major aerospace actors, SME, RTO and an university) will prepare a demonstrator of green high thrust engine (GTHE) based on liquid hydrogen using: - The latest advances in additive manufacturing to reduce the cost and number of engine parts, - Artificial Intelligence and machine learning to develop the first space engine health Monitoring System in Europe necessary to implement reusability, - New ultra-low-cost subsystems as engine ignition system, nozzle extension, electric valves and multi-functional lines. Therefore, ENLIGHTEN-ED will demonstrate the ability of such an ultra-low-cost engine to be rapidly operational and available for all European launcher families and thus strive to increase the competitiveness of European GTHE.

Keywords: space propulsion,hydrogen,green high thrust engines,green hydrogen,additive manufacturing,ai,demonstration,test platform,health monitoring,reusability
Breaking down barriers to foster new Cyclodextrin-based applications for healthcare by implementing sustainable design principles (Bicyclos)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy,Hungary,Belgium,Spain,Argentina,United States,Türkiye,Ireland
Call: MSCA Staff Exchanges 2022 (HORIZON-MSCA-2022-SE-01, 2022)
Start date: 2023-09-01
End date: 2027-08-31
Duration (months): 48.0
Total project cost (EUR): 1435200.0
EU funding (EUR): 1297200.0
Participants: 13
Project status: SIGNED

Cyclodextrins (CD) have already gained several market applications as excipients in drug and vaccine formulations. They are very appealing platforms for the development of therapeutic applications and new CD-based systems are continuously proposed. In this frame easily prepared CD polymers frequently outstand the performance of the corresponding CD monomers. Nevertheless, application of new CDs as drug or delivery system in the clinics does not take off in spite of their most promising features. This is mainly due to a lack in transfer of knowledge between the academic world and the private sector focusing on CD for biomedical applications. The consortium formed by a multidisciplinary team, all with interest in CD and nanomedicines, accepts the challenge to bring CD-based systems closer to clinical application. To reach this goal an intense secondment scheme for young and experienced researchers is envisaged with activities that are all contributing to the scientific pursuit of CD progress. Activities focus on the design of sustainable syntheses of new CD, full characterization of new functionalized CD, the preparation of CD delivery systems for therapeutics and the study of the biological behavior of the CD-based nanomedicines in 2D and 3D models. The teams will embrace, already from the design stage, the production standards affording compliance with GMP for medicine development and prefer strategic approaches in line with the EU 2030 Agenda for Sustainable Development. The consortium features 11 partners with 4 coming from the private sector. Two of them hold concrete interest in the exploitation of research results as their core business focuses on CD for biomedical applications. This intersectoral and interdisciplinary team will foster new applications of CD-based systems as drugs, delivery systems or sensors and participating staff will enrich their profile with scientific and soft skills that are easily transferred to other research topics or sectors.

Keywords: cyclodextrins,dna rna delivery,computational chemistry,3d models for drug development
Text and Idea of Aristotle's Science of Living Things (TIDA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 2447385.0
EU funding (EUR): 2447385.0
Participants: 1
Project status: SIGNED

Text and Idea of Aristotle’s Science of Living Things (TIDA) pursues two objectives, one philosophical, the other philological, both of which can only be achieved in tandem: subjecting Aristotle’s treatise on the soul, the De Anima (DA), and related treatises, to a new and comprehensive philosophical interpretation, while making available the original Greek texts in a way that complies with the standards of contemporary textual criticism. Philosophically, the aim is to replace the interpretive approach that governed philosophical discussions around the DA for the past 5 decades with a more coherent and philosophically more informative interpretation. According to the received approach, the argument of the DA falls into the domain of ‘philosophy of mind’. This assumption, fruitful though it was for our understanding of many of the DA's arguments, obfuscates the main aim and purpose of the treatise. TIDA shows how the DA is not concerned with the philosophy of mind as such, but with defining the first principle of the science of living things; we show how the DA divides explanatory labour with the other treatises pertaining to that science, and – most importantly – what the resulting scientific theory of living things has to say about the issues of the philosophy of mind. Philologically, the goal is to produce reliable critical editions of the relevant texts, print and digital, which we – astounding as it might seem – still do not possess. As the constitution of the texts will depend on the philosophical evaluation of alternative manuscript readings, only the closest collaboration between textual critics and philosophers will yield progress. There is reason to expect improved original texts and a genuinely new and more informative perspective on Aristotle on the mind. In effect, TIDA consists in a five-year interdisciplinary research team, designed to give future philosophical and philological work on Aristotle’s science of living things a new and lasting foundation.

Keywords: joint philosophical philological undertaking,aristotle,theory of living things
Probing new physics via precision CP violation measurements in charmless B-meson decays (SimDalitzCPV)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-11-01
End date: 2027-10-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

The amount of CP violation in the Standard Model (SM) of particle physics is not sufficient to explain the matter-antimatter asymmetry in the Universe, and thus searching for new CP-violating sources beyond the SM is of high priority in particle physics. The goal of this fellowship is to address this challenge by performing a novel measurement of CP violation simultaneously in the Bs -> KS K+ pi- and Bs -> KS K- pi+ decays. The two decays have dominant contributions from the b->s loop transition to which New Physics (NP) effects could have sizable contributions. The method will first be developed with a standalone study. This will investigate several factors that can affect the precision of the measurement of CP-violating observables in Bs -> KS K+- pi-+ decays, including the sample size and the amplitude model variations. This will provide crucial insight for the subsequent measurement using real data and future studies involving two final states. The LHCb experiment has collected a large sample of Bs -> KS K+- pi-+ decays to date, which is expected to increase significantly in the next two years. This data sample will be used to perform the first decay-time-dependent Dalitz-plot analysis to the KS K+ pi- and KS K- pi+ final states simultaneously, and to determine the associated CP-violating observables. The results of the analysis will provide a novel method to test the SM. The theoretical interpretation of in terms of potential NP sources of CP violation benefits from U-spin relations with the companion Bd -> KS K+- pi-+ decay, which can be used to control hadronic uncertainties. Analyses of the Bd modes will require larger data samples, which are not included in the baseline plan of this project. However, this project will set the stage for these measurements, developing all necessary methodology for a systematically improvable precise test of the SM.

Keywords: new physics beyond the standard model flavour physics cp violation beauty meson charmless decay dalitz plot analysis
Boosting the One Health Research Excellence and Management Capacity of the Estonian University of Life Sciences (OH-Boost)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Estonia,Finland,Italy
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 1499375.0
EU funding (EUR): 1499375.0
Participants: 4
Project status: SIGNED

The aim of the OH-Boost project is to increase the research and innovation excellence as well as the management and administrative capacities of the Estonian University of Life Sciences (EMU, with a focus on the Institute of Veterinary Medicine and Animal Sciences) in the field of One Health. One Health is an increasingly important research domain, focused on different dimensions of how human, animal and environmental health are inseparably linked. Its core lies in the understanding that humans and animals share the essentials of life: the genome, disease-causing organisms, health, welfare and the environment and ecological ecosystem that affects both humans and animals. Already having in place strong preconditions to conduct excellent research in the field (previous research, infrastructure and equipment), EMU now seeks to advance its knowledge and skills in One Health and ultimately become one of the most acknowledged research organizations in the field in Europe and worldwide. As one of the means to move towards this goal, EMU will team up with two of the leading universities in the related fields of One Health – the University of Helsinki (UH) and the University of Milan (UniMi). The University of Tartu (UT) will also join the project as EMU’s long-term local cooperation partner who offers human health expertise to support EMU’s expertise in animal health and the environment so that One Health topic are explored from a multidisciplinary and holistic perspective. The OH-Boost project seeks to combine EMU’s and UT’s competences to strengthen One Health research in Estonia, mentored by UH and UniMi. This includes knowledge transfer and capacity-raising activities as well as joint efforts to increase EMU’s research profile and international visibility.

Keywords: one health,animal human environmental health,disease biomarkers,extracellular vesicles,host pathogen interactions,foodborne diseases,antimicrobial resistance,3d modelling
A companion magnetic sensor for in operando detection of magnetic biosynthesis in cancer and neurodegenerative models (BioMag)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-10-01
End date: 2024-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Iron is essential for all life forms as it is a core component of many vital metabolic processes. In humans, iron homeostasis is controlled by sophisticated processes regulating its storage, transport, and export. More recently, the role of iron in diseases also emerged with ferroptosis being a form of cell death that is implicated for instance in the onset and progression of cancer or neurodegenerative disorders. Here, we focus on another intriguing type of iron in the body: the magnetic iron, which seems to be involved in both homeostasis and crippling pathologies, but which goes largely unnoticed to date. And yet, the presence and role of such biomagnetic iron offer a significant opportunity for novel therapeutic approaches. One explanation as to why this an unmet need most certainly stems from the lack of existing technologies that can detect the signature of biomagnetic iron in live human cells in real time. The solution brought by BioMag PoC project is to make possible the in operando monitoring of intracellular biogenesis of magnetic iron in human cells, in advanced cancer and Alzheimer’s models. To do so, the project proposes a unique (ultra)sensitive magnetic sensor integrated with bioreactors to enable the real-time measurement of magnetic nanoparticles biosynthesis in the cellular environment. The usefulness of this device goes well beyond the scope of our main ERC research, as it can have a significant impact on (i) identifying novel therapeutic approaches to diseases by detecting iron-based new druggable targets, (ii) addressing key questions related to iron metabolism towards novel diagnostics, and (iii) proposing a novel type of biogenic nanomedicines.
Cutting-edge food waste solution for restaurants (Binspector)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Netherlands
Call: Green Deal innovations for the Economic Recovery (HORIZON-EIC-2021-ACCELERATORCHALLENGES-01, 2021)
Start date: 2022-03-01
End date: 2024-02-29
Duration (months): 24.0
Total project cost (EUR): 3445875.0
EU funding (EUR): 2412112.0
Participants: 1
Project status: CLOSED

Worldwide, one-third of all food production is wasted, 15% of which is generated by restaurants, hotels and caterers who lack the tools to reap the benefits of reducing food waste. Our product, Binspector, combines a smart camera, a smart scale and artificial intelligence image recognition technology to automatically register all food going to waste and supply actionable insights to chefs on how to optimize inefficiencies. Integrated with external systems, our product will even pre-fill restaurant ordering systems. We offer our Product-as-a-Service to professional kitchens for a monthly fee with no upfront costs. It will allow an average kitchen to decrease its ecological footprint and food waste level by 70% and easily save over €30,000 annually, resulting in a net profit margin increase of up to 2%. The market is estimated to be worth €7,8B in Europe alone. Founded in 2019, Orbisk is a Dutch start-up with a team of 24 engineers, data scientists and commercial specialists.

Keywords: image recognition,commercial kitdchens,food waste,hospitality
Research and development of a highly automated and safe streamlined process for increased Lithium-ion battery repurposing and recycling (REBELION)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Cross-sectoral solutions for the climate transition
Action type: Research and Innovation actions
Partnership: Batteries (co-programmed)
Countries involved: Spain,Germany,Italy,United Kingdom,Slovakia
Call: Streamlined collection and reversed logistics, fully automated, safe and cost-efficient sorting, dismantling and second use before recycling (Batteries Partnership) (HORIZON-CL5-2022-D2-01, 2022)
Start date: 2023-06-01
End date: 2026-11-30
Duration (months): 42.0
Total project cost (EUR): 3764298.75
EU funding (EUR): 3764298.5
Participants: 12
Project status: SIGNED

The increasing e-mobility will trigger a battery waste problem (9Mtons/year by 2040) despite that many of the used LIBs are suited for 2nd-life applications for an additional 10 years, representing an opportunity to diminish energy and raw materials dependencies in Europe. Technical hurdles are preventing the re-use and recycling of Li-ion batteries. Besides the heterogeneity of the battery stock, assessing their condition for further usage is a slow process performed with equipment not suited for industrial contexts while. Dismantling packs and modules is in addition a costly and slow manual process because its automation faces extremely complex, multi-scale, cluttered and densely packed environments. REBELION will validate two circular schemes (including Light e-vehicles) to maximise 2nd life utility and domestic applications, enabled by a disruptive fast battery testing based on Electronic Noise Analysis, and an autonomous pack and module disassembly system with re-configuring capabilities for the ongoing battery types and formats. Additionally, a novel labelling system supported with blockchain, digital battery passport and ecolabel technology will provide key information to dismantlers, recyclers, re-manufacturers and users. Processing large volumes of used batteries increases the risks of thermal runway incidents, requiring thus novel safety protocols and systems. REBELION will add thermal monitoring and the design of a smart container for storage and transportation with thermal and gas sensing layers to monitor the limiting oxygen index and lower explosive limits, and a cooling system that activates when thresholds are surpassed. REBELION consortium covers all the value chain, including advanced robotic line and car manufacturer, bringing key knowledge, proprietary technology, and pilot validation facilities. The combination of 4 research centres and 7 industrial partners will ensure technology transference from lab to industrial context.

Keywords: li ion batteries eco costs digital battery passport health diagnosis thermal runaway automation