Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Velotix Data Security Platform (DSP) GenAI -Driven DSP as a Knowledge and Experience (K&E) Centre for Policy Compliance (VLTX-GENAI)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Velotix, a startup in data security policy enforcement, uses advanced AI to revolutionize database security and worldwide regulatory compliance for enterprises. Its innovative Data Security Platform (DSP) tackles challenges posed by regulations such as GDPR, enhances human interactions with databases, and ensures secure data access. Under the scope of the EU funding proposal, Velotix's DSP aims to employ large language models (LLMs) and retrieval-augmented generation for automated policy creation and enforcement, real-time monitoring of human interactions, and systematic Red Team access control testing. The platform analyzes human behavior and natural language requests for structured and unstructured data, compiling these with free-text policy documents. LLMs and sophisticated prompt engineering convert these documents into dynamic vectorized rule policies. Currently targeting the BFSI segment (€29 billion in 2024), Velotix aims to capture 3.5% of this market. In the future, with EU blended finance support, Velotix plans to expand into the healthcare and telecommunication segments, which, together with the BFSI market, represent 50% of the global market. The analysis indicates that the total market segment will reach €230 billion by 2032, with a CAGR of 16.4%. The company's competitive edge includes AI-driven automation, continuous monitoring, a superior user experience, a data marketplace, and state-of-the-art dynamic GenAI database security policy enforcement. With anticipated funding, Velotix plans to expand its impact across various sectors in the EU, fostering innovation and strengthening data management practices. Velotix aims to lead AI-driven data security, revolutionizing organizational data interactions while maintaining strict compliance and security standards. This approach will reinforce the EU's position as a global leader in responsible data management and innovation.

Keywords: genai,regulation,gdpr,llm,retrieval augmented generation rag,dynamic sql,data marketplace,policy automation,digital single market dsm,user interface threat detection,knowledge centres
An All-Optical computer for solving Hard Optimization Problems (LightSolver)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2024-12-01
End date: 2026-11-30
Duration (months): 24.0
Total project cost (EUR): 3571427.14
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

LightSolver is developing a new paradigm for computing. We have developed a revolutionary Laser Processing Unit (LPU) that outperforms traditional CPUs and GPUs in specific tasks, such as optimizing supply chains, designing new materials, and managing financial portfolios. This new LPU – Laser Processing Unit can process NP-hard problems orders of magnitude faster because it has no electronic gradients inside the processor. This LPU is small as a desktop size, operates at normal conditions, and consumes minimal power. This full-stack unit includes three layers to provide the most accurate solution within the shortest time frame: a user interface, an operating system and Hybrid Hardware. Our proprietary hybrid solver combines an all-optical solver based on a pure laser processing unit (LPU) with a digital enhancement that increases the number of spins (variables) whilst decreasing the complexity of the problem. All industries will benefit from optimization problems, including government, healthcare, financial services, retail, manufacturing, energy and utilities, transportation and logistics, and more. Asset optimization is gaining notable importance in the manufacturing and energy sectors due to the possibility of obtaining real-time data LightSolver’s platform offers distinct advantages from competitors: • Faster and More Accurate Solutions • Cost-Effective Manufacturing and Energy Consumption • Cloud Accessibility and On-Premises Capability • Unique Assisting Algorithms • Scalability for Complex Problems

Keywords: optimisation computer science,scientific simulation,quantum mechanics
Harnessing Granzyme Pathways: Developing Novel Antimicrobial Therapies Against Resistant Bacterial Strains. (MicroGRANZ)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Poland
Call: ERA Fellowships (HORIZON-WIDERA-2024-TALENTS-02, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 179006.16
EU funding (EUR): 179006.16
Participants: 1
Project status: SIGNED

Antimicrobial resistance (AMR) is a critical global health threat, causing over 4.3 million infections annually in OECD countries, with 1.7 million in the EU/EEA. AMR leads to higher mortality, while the economic impact is severe, with increased healthcare costs due to prolonged hospital stays and the need for more expensive treatments, affecting both productivity and societal well-being. MicroGRANZ seeks to explore the antibacterial potential of granzyme proteins—Granzyme A, Granzyme B, and Granzyme M—as novel therapeutic agents to combat antibiotic-resistant bacteria. Granzymes, produced by cytotoxic T lymphocytes and natural killer cells, assist immune cells in pathogen clearance, but also kill extracellular bacteria directly. Granzymes offer great potential as an alternative to antibiotics; however, their mode of action is not well understood. In MicroGRANZ I will employ interdisciplinary approaches including live-cell microscopy and robotic liquid handling, where thousands of bacteria together with host cells can be monitored over time. This will provide a new understanding of granzyme’s specificity for different bacteria, and in combination with immune cells for cell-assisted killing. I will also improve their effectives by combining different granzymes together, also with other host molecules like Granulysin and Perforin, which enable them to get inside cells. Finally, I will use nanomaterials for enhanced and targeted delivery and controlled release into cells. By investigating how granzyme proteins can be used to tackle resistant bacteria, MicroGRANZ aims to develop innovative immunotherapies that address the global challenge of AMR. The outcomes could pave the way for new treatments that strengthen the innate immune response, aligning with international public health priorities and contributing to improved patient outcomes. Ultimately, MicroGRANZ will also make a step change to my career in an interdisciplinary environment of IPPT PAN.

Keywords: antimicrobial resistance,granzyme proteins,infectious disease,immunotherapy,cytotoxic t lymphocytes,natural killer cells,high content microscopy,targeted drug delivery,nano drug formulation
Accelerating European AI with Privacy Enhancing Tech to Protect Every Identity in Public (brighter AI)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Privacy concerns have surged as AI and ML advancements increase data consumption, and regulations (GDPR, CCPA, etc.) cause companies to face challenges balancing innovation and privacy. EU firms struggle with GDPR compliance and competitive AI advancements due to limited anonymization tech. Current anonymization methods often compromise data quality, impacting industries reliant on compliant data for AI and research. brighter AI uses patented technology to help protect every identity in public, by automatically anonymizing facial features, license plates, or other modes of personal identification, when it comes to commercial use. Simply put, we exchange highly personally identifiable information such as faces and license plates with synthetic placements, while maintaining gender, age, or mood. The new image preserves the key parameters but no longer bears enough resemblance to the original image. With the EIC funding, we can dramatically accelerate the development of our Edge solution and create a secure repository for public DNAT anonymized data with our Data Hub. We founded Brighter AI Technologies GmbH in 2017 in Germany and target the €1.1 trillion public video data market, with a pricing model based on Consumption (€10-€120/hour), Consultation (engineering: €1,500/day) and Edge (€3,000-€35,000/unit) charges. Our diverse team of 22 members, led by Co-Founder and CEO Marian Gläser won awards, such as the the “ECSO STARtup Audience Award” (2023), the German Digital Award with Spark, 2024 Tiger Award's Visionary of the Year, and has been selected as one of the latest European Cybersecurity startups out of 1,500 companies in 2023. Our ultimate venture scenario and growth purpose is to become a major European player in data privacy of public video anonymization. By creating a centralized hub for compliant data on the edge, we will enable high-scale video analytics with a new data protection technology based on generative AI, thereby enhancing EU competitiveness.

Keywords: ai based image and video anonymization,artificial intelligence,redaction software,anonymization,compliance,privacy protection,computer vision,precision blur,deep natural anonymization dnat
CMXsafe: A novel cloud-based secure communication architecture to simplify emerging IoT regulatory compliance (CMXsafe)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-06-01
End date: 2026-05-31
Duration (months): 24.0
Total project cost (EUR): 215534.4
EU funding (EUR): 215534.4
Participants: 1
Project status: SIGNED

Security in Internet-of-Things (IoT) environments has become a major concern. This is partly due to a large number of remotely exploitable IoT vulnerabilities in service authentication and access control combined with the lack of timely technical support. Furthermore, emerging regulations require changes in IoT deployments difficult to apply in a generalisable fashion. This difficults reusability, and scalability, and increases development and management costs. Therefore, the objectives of CMXsafe are twofold: a) Provide a proxy-layer communication architecture devised to offload security communications functions from IoT applications into application-agnostic proxy modules. This simplifies IoT device application designs and the deployment of security updates. b) Devise CMXsafe components abiding by the Security Evaluation Standard for IoT Platforms (SESIP) methodology, accepted by the European Committee for Standardization to facilitate composite cybersecurity certification schemes. To accomplish this, I will describe the technical requirements according to the SESIP standard and implement a testbed comprising 8 IoT devices and the cloud side of CMXsafe architecture. These activities will take place at the University College of Dublin School of Science, at the ASEADOS Lab where I will be supervised by Prof. Anca Delia Jurcut. CMXsafe will allow me to improve my competencies in cybersecurity regulations, cloud architectures and valuable transferable skills required to succeed in the industry. CMXsafe will guarantee a successful two-way transfer of knowledge because CMXsafe combines my background experience in security decoupled communications with the host’s experience in cybersecurity, regulations and business relations with industry partners. Therefore, CMXsafe will contribute with an IoT proxy-based communication architecture that facilitates security updates and regulation compliance.

Keywords: communication architecture,proxy layer,security decoupling
Arkadia Space: The new generation of sustainable space engines (Arkadia Space)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Arkadia Space is a pioneering company in the space propulsion industry, focusing on developing sustainable and non-toxic propulsion systems using hydrogen peroxide. Founded in 2020, Arkadia has established itself as a leader in creating green propulsion alternatives, aiming to replace hazardous chemicals like hydrazine. With a growing team and partnerships with major entities like the European Space Agency, Arkadia is committed to making space exploration more sustainable and accessible. The company's key innovation is the 200N bipropellant thruster, designed to be eco-friendly and cost-effective, offering a significant reduction in lifecycle costs and operational hazards compared to traditional systems. Arkadia's propulsion systems address the environmental and safety concerns prevalent in the current market, which relies heavily on toxic propellants. Arkadia's business model targets the B2B and B2G sectors, aiming to cater to satellite manufacturers, space agencies, and commercial space companies. With the space propulsion market expected to grow significantly, Arkadia plans to capture a substantial market share by offering advanced, sustainable solutions. The proposal outlines a comprehensive approach to advancing the technology from TRL 5 to TRL 9, focusing on enhancing the reliability, efficiency, and safety of the propulsion systems. This development is critical as it prepares the technology for market readiness, ensuring it meets the stringent demands of space applications. Arkadia's strategy also includes significant investment in R&D and scaling up operations to meet the anticipated demand in the burgeoning space logistics and satellite services market. The company's efforts are aligned with global sustainability goals and the push towards reducing the environmental impact of space exploration.

Keywords: green propulsion,sustainable fuels,hypergolicity,advanced manufacturing techniques,novel materials,satellite propulsion
Coordination of national research programmes in Agri-Food and biotechnology - Joining forces of ERA-Net Cofunds, EJP and self sustained initiatives (Green ERA-Hub)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Reforming and enhancing the European R&I System
Destination: Reforming and enhancing the European R&I System
Action type: Coordination and support actions
Countries involved: Germany,Netherlands,France,Ireland,Hungary,United Kingdom,Belgium,Denmark,Italy
Call: Support for policy makers – Programme level collaboration between national R&I programmes (HORIZON-WIDERA-2021-ERA-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 3499508.75
EU funding (EUR): 2823600.0
Participants: 12
Project status: SIGNED

The Green ERA-Hub (GEH) represents 15 currently active EU ERA-Net Cofunds and self-sustained initiatives in the field of Agri-food and biotechnology. Together with already ended predecessor initiatives, they represent 29 co-ordination actions in which more than 1100 Mio Euro funding has been mobilised via 89 transnational calls. The ERA-Net scheme is a success model for transnational co-operation of national research programmes. The partners consider GEH an ideal measure to continue and extend this fruitful co-operation. The aims of GEH are to: - continue to build on previous achievements and further enhance cross-sector collaborations between Agri-food and biotechnology ERA-Nets, through joint transnational funding of collaborative research projects - valorise and implement joint activities supporting the market, regulatory or societal uptake of results after the end of individual ERA-Nets - identify common research and innovation priorities, agreed upon by the participating national programmes, and address them via new joint calls - preserve best practice and managerial competences - contribute to the planning and complement the implementation of the new HEU Partnerships and Missions - broaden the actions and impact of initiatives towards stakeholders and in terms of geographical coverage - contribute to achieve the strategic goals of the SDGs, in particular zero hunger, industry innovation and infrastructure, responsible consumption and production, life on land, partnership for the goals, the farm2fork strategy and EU's Green Deal. GEH will provide clear perspectives for ERA-Net (Cofunds), national research funders and researchers in the Agri-food and biotechnology sector to find dedicated support at the level of information, communication, co-operation, networking and joint transnational funding that best fits their needs. In turn, GEH will contribute to maintaining and strengthening EU's highly competitive position in Agri-food and biotechnology research.

Keywords: cooperation,coordination,era net cofunds,ejp,joint funding,
Revealing genes that mediate the CIN-induced interferon-inflammatory response using a Genome-wide CRISPR screen coupled to a Suicide Gene Switch. (CRISPRCINIMM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-01-01
End date: 2024-12-31
Duration (months): 24.0
Total project cost (EUR): 187624.32
EU funding (EUR): 187624.32
Participants: 1
Project status: CLOSED

Chromosomal instability (CIN) and the resulting aneuploidies can fuel the dramatic karyotype changes characteristic of tumorigenesis, helping tumors to alter the expression of immune checkpoints and evolving phenotypes related to immune evasion or stimulation. Anti-tumor immunity appears to be dependent on the type and origin of the tumor, while immune evasion has become an obstacle to designing effective anticancer therapeutics. Understanding when CIN promotes or suppress anti-tumor immunity is therefore needed. However, the mechanism and initiators by which this adjustment occurs and the role that aneuploidy, CIN or specific karyotypes have in this transition are still in the dark. In order to understand how CIN drives tumor evolution, we need to know how CIN guide cells into different immunogenic responses. Identifying the genes that adjust the role of CIN and aneuploidy in immune evasion can therefore help us unravel the origins of malignant growth and in the future develop more appropriate therapeutic approaches. My project plan is set to find the genes that trigger and connect chromosome missegregation to the interferon-inflammatory response in cells suffering from CIN using an unbiased genome-wide CRISPR KO screen coupled to a suicide gene switch in human fibroblasts. The use of a suicide gene switch, normally used for cell-based therapy, allows separation of cells that have lost the inflammatory pathway while the screen, along with a next generation sequencing, will find the genes related to that loss. This screen will serve as a base to understand what underlies cancer immune evasion in chromosomally unstable cells.

Keywords: cin,inflammatory response,cancer,crispr,suicide genes
SImple and RObust laser source with EU supply chain and Cavity and injection-free Optical parametric oscillator for spaceborne lidar (SIROCO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Space
Destination: Open Strategic Autonomy in Developing, Deploying and Using Global Space-Based Infrastructures, Services, Applications and Data
Action type: Research and Innovation actions
Countries involved: France,Germany,Sweden
Call: Space technologies for European non-dependence and competitiveness (HORIZON-CL4-2024-SPACE-01, 2024)
Start date: 2024-12-01
End date: 2028-11-30
Duration (months): 48.0
Total project cost (EUR): 3527290.21
EU funding (EUR): 3071640.77
Participants: 10
Project status: SIGNED

SIROCO (SImple and RObust laser source with EU supply chain and Cavity and injection-free Optical parametric oscillator for spaceborne lidar) aims to reach EU independence for high-power lasers in the eye-safe region. A solution based on wavelength conversion from a 1µm laser will be matured, ensuring EU supply chain independence for power laser emission in the 1.5-3µm range. Such breakthrough laser will build the foundation of next greenhouse gases (GHG) spaceborne sensors by Integrated Path Differential Absorption Lidar (IPDA), by which GHG of interest can be probed in the 1.6μm or 2μm eye-safe regions. To meet the stringent spectral, spatial beam, and power properties required, efficient and versatile wavelength converters such as Optical Parametric Oscillators (OPOs) pumped by mature 1μm power lasers are key enabling technologies. This is also the approach in the European Methane Remote Sensing Lidar Mission (MERLIN). SIROCO will mature innovative critical optical space technologies to TRL6, including a hybrid fiber/bulk 1μm laser combined with a new Backward Wave OPO (BWOPO) concept. This will lead to a simplification shock compared to the state of the art, as no optical cavity is required (higher robustness and easier integration), nor any OPO seed source (higher compactness and simplicity in wavelength control). It will increase EU competitiveness by faster integrated, less risky, more sensitive future space IPDA. SIROCO will develop nonlinear crystals to ensure an EU supply chain, which are key components for various applications (general laser physics, IPDA emitters, quantum applications). Their exploitation path towards future space LIDAR and quantum communications will be delivered through two public technical roadmaps. SIROCO is a 4-year 3MEuros valued action, gathering renown research & academic organisations and SMEs, and supported by an Advisory Board with experts from the European Space research, Atmosphere Science and Quantum communities.

Keywords: space lidar emitter,nonlinear crystals