Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Efficient and affordable Zero Emission logistics through NEXT generation Electric TRUCKs (NextETRUCK)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Clean and competitive solutions for all transport modes
Action type: Innovation actions
Partnership: 2ZERO (co-programmed)
Countries involved: Netherlands,Belgium,Spain,Greece,Austria,Türkiye,United Kingdom,Germany,Hungary
Call: Nextgen vehicles: Innovative zero emission BEV architectures for regional medium freight haulage (2ZERO) (HORIZON-CL5-2021-D5-01, 2021)
Start date: 2022-07-01
End date: 2026-09-30
Duration (months): 51.0
Total project cost (EUR): 14672510.0
EU funding (EUR): 11365811.5
Participants: 23
Project status: SIGNED

The volume of the commercial freight sector is expected to increase towards 2050, especially in the medium to heavy truck modes (N2 and N3 type). However, in parallel to that, the recent European climate goals bring challenges for the transport sector. Given the fact that the typical vehicle development cycles can be of 5-7 years, an immediate collective and collaborative action from the research organizations, business strategists, technology companies and OEMs is necessary. The result of this would be to attain high-TRL concepts that are ready to roll out in the European and global market, where there is more room for a gradual adoption at the consumer side. In any case, given the fact that there are substantial technological and business steps are being taken in the zero-emission transport field, the next 30 years towards 2050 potentially requires more dramatic changes than the last 30 years (i.e., since 1990). NextETRUCK aims to address different optimization challenges regarding tomorrow’s urban and suburban logistics for medium duty vehicles into systems-approach that is reliable, strongly integrated, affordable, and flexible enough to re-applied to different applications via dedicated tools/methods. The overarching objective of the NextETRUCK project is to play a pioneering role in the decarbonization of the vehicle fleets, via demonstrating next generation e-mobility concepts consisting of holistic, innovative, affordable, competitive and synergetic zero emission vehicles and ecosystems for tomorrow’s medium freight haulage, while aiming significant leap of knowledge at component, vehicle, fleet, infrastructure and ecosystem levels, via innovations at e-powertrain components and architectures, smart charging infrastructure and management, improved thermal design of the cabin, fleet management systems with IoT and digital tools.

Keywords: zev,e powertrain,digital twin,smart charging,fleet management,thermal management,tco,medium duty
INNOVATIVE CO-CREATION SOIL HEALTH LIVING LABs (iCOSHELLs)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Soil health and food
Destination: Soil health and food
Action type: Research and Innovation actions
Countries involved: Sweden,Germany,Italy,Bulgaria,Spain,Greece,Denmark,Belgium
Call: Co-creating solutions for soil health in Living Labs (HORIZON-MISS-2023-SOIL-01, 2023)
Start date: 2024-09-01
End date: 2028-08-31
Duration (months): 48.0
Total project cost (EUR): 11999872.5
EU funding (EUR): 11999872.5
Participants: 41
Project status: SIGNED

European soils face pressing conditions for their health. An alarming 60-70% of EU soils are considered unhealthy, attributed to factors such as pollution, urbanization, and intensive agriculture, further exacerbated by climate change. This degradation results in economic, societal, and environmental repercussions, including decreased land productivity, migration, land abandonment, and biodiversity loss. Addressing this challenge necessitates holistic measures, especially since soil restoration can take centuries. The project initiative, aligning with various EU policies, emphasizes the importance of comprehensive soil restoration efforts. It plans to establish six Soil Health Living Labs (SHELLs) across diverse EU climatic zones, including Sweden, Spain, Spain-France, Italy, Greece, and Bulgaria. These labs are envisioned as innovation hubs, tailored to address the EU's specific soil health objectives, notably objectives 4, 6, and 8. Through collaborative efforts within these SHELLs, the goal is to develop, test, and validate potential solutions, ensuring scalability beyond their immediate regions. iCOSHELLs places a strong emphasis on inclusive stakeholder engagement, from researchers to landowners. Its systematic approach includes building stakeholder capacities, bridging gaps between science and practical applications, deepening understanding of soil indicators, replicating effective soil recovery methods, and championing supportive soil health policies. Additionally, iCOSHELLs seeks to redefine the concept of Living Labs (LLs). Challenging the traditional model, which often revolves around isolated research entities, iCOSHELLs envisions LLs rooted in co-creation, broad engagement, and real-world application. This transformative vision aims to evolve existing SHELLs into standardized, widely recognized labs, setting a foundational blueprint for future LLs. Moreover, as a comprehensive soil data repository, iCOSHELLs promotes collaboration, ensuring replicable.

Keywords: soil health,soil restoration,living labs,real world applications,stakeholder engagement,policy recommendation,biodiversity conservation sustainability
Astrocytic metabolism-driven epigenetics at the cornerstone of cognitive aging (NeuroSTARS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Spain
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 2467500.0
EU funding (EUR): 2467500.0
Participants: 1
Project status: SIGNED

Cognitive impairment is a major source of disability and dependence during aging. Up to 40% of dementia cases are attributable to modifiable environmental risk factors, namely lifestyle, which can be actionable for prevention before the onset of cognitive decline. Physical activity and nutrition comprise promising modifiable factors affecting cognitive aging, but how the lifestyle affects cognition is not fully explained. Because of their unique location at the interface between blood vessels and synapses, astrocytes are strategically positioned to translate lifestyle contexts into specific cognitive shapes. Work from our group has demonstrated that astrocytic metabolism is remarkably dynamic and alternates lactate, ß-hydroxybutyrate and acetyl-coenzyme A production. Importantly, preliminary data indicate that these metabolites directly bind histones within astrocytes as epigenetic regulatory adaptive mechanisms. In NeuroSTARS, we will address whether such epigenetic adaptation is dictated by lifestyle-driven modulation of astrocytic metabolism to underpin cognitive performance across the lifespan. In mice subjected to controlled physical activity and dietary contexts, in combination with genetic manipulation of pivotal metabolic pathways in astrocytes, using cutting-edge metabolism and cognition assessment tools, we will (i) identify how astrocytic metabolism adapts to different lifestyle contexts throughout life, (ii) decipher the lifestyle-induced metabolic pathways that impact on metabolites-driven epigenetic regulation in astrocytes, and (iii) define the mechanism that causally links lifestyle-induced metabolism-driven epigenetic regulation within astrocytes with cognition across the lifespan. The expected output will reveal that the metabolism of astrocytes is instrumental in the coupling between lifestyle and age-associated cognitive decline, challenging the view that it merely serves to meet the energy needs of neurotransmission.

Keywords: epigenetics,astrocytes,metabolism,cognitive decline
Wireless magnetothermal entero-modulation (MagGelGut)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Israel
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-10-01
End date: 2029-09-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Gastrointestinal (GI) disorders affect over 40% of the world population. Pharmacological agents that modulate cell function and subsequently impact processes involved in such disorders, suffer from limited spatiotemporal specificity and accompanying side effects. Despite the advances in the field of bioelectronic medicine which have enabled localized modulation of electrogenic cells, it still requires invasive hardware, impeding their use in soft and continuously moving organs. We recently showed that magnetic nanoparticles injected into a deep solid organ and exposed to alternating magnetic fields (AMFs), dissipate heat that can trigger localized calcium signaling mediated by endogenously expressed heat-sensitive ion channels. However, penetrating the sensitive and hollow intestine tissue is challenging. This proposal aims to develop a novel approach for remote activation of the intestine via adhesive materials. To achieve this goal, an implantable, biocompatible and stretchable magnetic gel will be designed with controlled adhesiveness, allowing for its effective adherence to tissues and detachment. The magnetic gel can be remotely controlled to dissipate heat under AMFs. Prior to attempting thermal stimulation of the intestine, a proof-of-principle demonstration will be performed in the adrenal gland, a solid organ which expresses heat-sensitive ion channels. Next, the gel properties will be tailored to the intestinal tissue and the activation of heat-sensitive ion channels in the colon will be thoroughly characterized ex vivo. Finally, in vivo entero-modulation will be demonstrated, while addressing barriers associated with use of magnetic nanomaterials in in vivo models and modulating parameters to achieve short latency between stimulation onset and cell response. Ultimately, I propose to achieve wireless on–demand control of calcium influx and neuropeptide release in the colon, to address gastric symptoms of disturbed motility and inflammatory response.

Keywords: magnetic nanoparticles,bioadhesive,trpv1,motility symptoms,inflammatory bowel diseases,alternating magnetic fields,hydrogel
Widening the European capabilities for delivering the next generation data-driven reference European models and methods towards silent and green aircraft operations around airports (WIDERA-NEEDED)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Research and Innovation actions
Countries involved: Austria,Cyprus
Call: Hop on Facility (HORIZON-WIDERA-2023-ACCESS-06, 2023)
Duration (months): 33.0
Total project cost (EUR): 471003.75
EU funding (EUR): 471003.75
Participants: 2
Project status: SIGNED

NEEDED is a funded Horizon project that aims to deliver the next generation of reference models and methods for estimating present and future aircraft emissions (pollutants and noise), and assessing how these affect the environment and the health of people living in the vicinity of airports. The overall project vision is to advance predictions of airport Local Air Quality (LAQ) and noise beyond the current state-of-the-art, while supporting the introduction of transformative aircraft technologies and new regulations for more environment-friendly aircraft operations. Aligned with this vision, the ambition of the proposed Hop-On Facility (HOF) is to strengthen the NEEDED consortium so that it can better address its objective to advance the state-of-the-art in LAQ modelling by establishing emission inventories for primary pollutants produced by current and future aircraft technologies, combined with highly resolved atmospheric dispersion models. This will be achieved by the Hop-On partner, namely the Cyprus Institute (CyI), which will bring high-level expertise and cutting-edge tools enabling novel combinations of observations and models for predicting impacts from aircraft emissions in the vicinity of airports that go beyond what was originally aimed by NEEDED. At the same time, the HOF will improve the research and innovation excellence of a widening beneficiary (i.e., the CyI) and advance its overarching goal to establish a regional research and innovation hub in Cyprus for research related to the atmospheric environment, and aim to develop sustainable solutions for addressing pressing challenges and supporting transition towards a green and digital economy. Beyond the immediate scope and duration of the HOF, the addition of the CyI to the consortium will strengthen a number of the current outcomes and wider impacts of NEEDED, as well as the wider multi-level objectives and impacts related to HORIZON-WIDERA-2023-ACCESS-06 call.

Keywords: air pollution,gas sensors,aerosol instruments,particle counters,air quality monitors,air quality modelling,dispersion models,human health effects
Driving agroecological transitions in the humid tropics of Central and Eastern Africa through traNsdisciplinary Agroecology Living LabS (CANALLS) (CANALLS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: France,Nigeria,Cameroon,Rwanda,Uganda,Germany,Switzerland,United Kingdom,Congo, The Democratic Republic of the,Burundi,Norway,Greece,Belgium
Call: Agro-ecological approaches in African agriculture systems (HORIZON-CL6-2022-FARM2FORK-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 6645513.69
EU funding (EUR): 6645513.06
Participants: 22
Project status: SIGNED

The humid tropics of Central and Eastern Africa hold much promise for enhancing food and nutritional security within and beyond Africa. With a rich variety of agroecological zones and diverse farming systems, they are home for a great part of the rural population and a large diversity of living organisms, offering vital ecosystem services and potential for sustainable development. Still, if we are to tap into this potential, we need to address the complex environmental, social and economic challenges they face, which in cases are exacerbated by conflict and high vulnerability. In this context, CANALLS aims to drive agroecological transitions in the humid tropics of Central and Eastern Africa via multi-actor transdisciplinary Agroecology Living Labs (ALLs). We start with 8 ALLs in DRC, Burundi, Cameroon and Rwanda, working alongside and enabling over 20,000 farmers and value chain actors to co-create and benefit from optimal combinations of agroecological practices focusing on crops that are vital for subsistence and economic development (cocoa, coffee, cassava, rice, maize). In parallel, we engage in solid multi-actor collaboration with rural communities, advisory services and governments to develop a holistic assessment framework and evaluate the socio-economic and environmental performance of the co-created practices (accounting for trade-offs and synergies). We use the comprehensive evidence generated to build capacity and share knowledge (practice abstracts, replication guidelines, policy recommendations) as well as to deliver fair, inclusive and sustainable business models along with services and tools for facilitating access to markets and enhancing demand for agroecological products. Our vision is to create a growing network of ALLs that leverages EU-AU cooperation to conduct transdisciplinary research, offer scientific support and drive coordinated action for delivering holistic solutions that help shape enabling conditions for agroecological transitions.

Keywords: agroecological transition pathways agroecology living labs central and eastern africa humid tropics climate change mitigation agri food systems resilience trade offs agroecology assessment
Meta-Learning of memristive devices for lifelong adaptation (MALEFICENT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Netherlands,Germany,Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 217076.16
EU funding (EUR): 217076.16
Participants: 3
Project status: SIGNED

The continued growth of artificial intelligence (AI) in the cloud is driving up global energy costs. As a result, a paradigm shift is taking place where new intelligent devices are placed right at the edge. MALEFICENT will create a new framework for implementing sustainable AI at the edge using standard and novel technologies. Neuromorphic systems using emerging memory devices such as resistive switching devices (ReRAM) or ferroelectric capacitors (FeCap), are a promising alternative for AI systems thanks to their energy efficiency and non-volatility. However, the deployment of these devices in real-world applications poses some challenges, due to their intrinsic variability and limited bit precision. I will use advanced learning techniques such as meta-learning to create a self-adaptive neuromorphic system based on emerging memory devices able to exploit the intrinsic features of the devices while mitigating their limitations. I will then apply it to a real-world environment, such as robotics. This will have a significant impact on the research of emerging memory technologies, by opening up the possibility of exploitation in an industrial context.

Keywords: meta learning spiking neural networks neuromorphic memristor online learning neurobotics edge computing
Providing operational economic appraisal methods and practices for informed decision-making in climate and environmental policies (PATTERN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Climate
Destination: Climate sciences and responses for the transformation towards climate neutrality
Action type: Research and Innovation actions
Countries involved: Spain,Belgium,Italy,Finland,France,Norway,Netherlands
Call: Improved economic methods for decision-making on climate and environmental policies (HORIZON-CL5-2021-D1-01, 2021)
Start date: 2022-06-01
End date: 2025-05-31
Duration (months): 36.0
Total project cost (EUR): 2999636.25
EU funding (EUR): 2999630.0
Participants: 13
Project status: SIGNED

The PATTERN project’s general objective is to improve practitioners’ capacity for decision making on climate and environmental policies, by developing an interactive online platform for the economic appraisal of policies and measures. To reach this general objective, the project will develop an operational integrated economic appraisal approach (WP3 and 4), deliver guidelines to bridge ex-post and ex-ante analyses (WP1), build and demonstrate an effective participatory process to create 5 Theories of Change (WP2), build a European Community of Practice for climate and environmental policymaking (WP6), and create a One-Stop-Shop for all policy and decision makers to access and use the project results easily. PATTERN will thus provide decision-makers, stakeholders, and the public with more realistic and operational ability to systematically assess their policies and their consequences. It will provide a basis for improving (i) methodologies, techniques and models for conducting economic appraisal of climate and environmental policies (ii) the broader policy evaluation framework and practices currently used in European countries and their regions and (iii) tailored analysis and engagement strategies structures for the participation and co-creation with relevant stakeholders and key actors to enhance operational capacities and improve the impact of European policies on climate and environment. Overall, results obtained from in-depth ex-post and ex-ante analysis of the PATTERN’s 5 case studies will bring new evidence on the effectiveness of various types of regulatory strategies, instruments and approaches for climate and environmental policies and insights for the design and evaluation of the implementation of major European policies.

Keywords: climate change,biodiversity,policy making,decision making,operational tools,methods,models,social sciences and humanities