Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Far-from-Equilibrium ATtractors at Ultra-Relativistic Energies (FEATURE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Slovenia
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-01
End date: 2025-09-30
Duration (months): 24.0
Total project cost (EUR): 171399.36
EU funding (EUR): 171399.36
Participants: 1
Project status: SIGNED

One of the grand challenges facing the high-energy physics community is understanding the far-from-equilibrium evolution of quantum chromodynamics (QCD). A recent innovation in the theory of far-from-equilbrium systems was the discovery of hydrodynamic attractors to which non-equilibrium solutions of microscopic configurations decay, losing knowledge of their initial conditions well before approaching thermal equilibrium. This project will take the critical step to bring theoretical understanding to the level of complexity required for realistic phenomenology, by fully characterizing the properties of the QCD attractor without resorting to simplifying assumptions done in the current preliminary studies. This will be done via the inclusion of fermionic degrees of freedom and by relaxing simplifying spatial symmetries. This proposal is possible due to the mixing of perspectives and skills, from Dr. Alexander Soloviev's (the researcher) deep knowledge of attractors and the physics of heavy ion collisions, and Prof. Sašo Grozdanov's (the supervisor) extensive expertise of magnetohydrodynamics and non-equilibrium field theory methods. The researcher will undergo training at the University of Ljubljana, cultivating the necessary analytic and numerical skills to meet the research objectives of the project and advance his career. The new insight gained will be applied to the phenomenological context to elevate the dynamical freeze-out process into a far-from-equilibrium process, thus leading to the full exploitation of data at experiments in the Large Hadron Collider and Relativistic Heavy Ion Collider. The attained knowledge will be also used to probe the attractor near the phase transition, providing vital insight into searches for the QCD critical point. Furthermore, the gained insight into attractors will provide an avenue to integrate magnetohydrodynamics into descriptions relevant for heavy ion collisions.

Keywords: quark gluon plasma,hydrodynamic attractors,far from equilibrium dynamics,magnetohydrodynamics
Strategic reasoning for socially good mechanisms (SEAL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 1
Project status: CLOSED

The design and evaluation of mechanisms for aggregating preferences is a central problem in Multi-Agent Systems (MAS). In such setting, we need to be able to aggregate individual preferences, which are conflicting when agents are self-interested. More importantly, the mechanism should choose a socially desirable (or "good") outcome and reach an equilibrium despite the fact that agents can lie about their preferences. The real-world applications of designing and verifying mechanisms for social choice are manifold, including fair division protocols, secure voting, and truth-tracking via approval voting. Although logic-based languages have been widely used for verification and synthesis of MAS, the use of formal methods for reasoning about auctions under strategic behavior as well as automated mechanism design has not been much explored yet. An advantage in adopting such perspective lies in the high expressivity and generality of logics for strategic reasoning. Moreover, by relying on precise semantics, formal methods provide tools for rigorously analyzing the correctness of systems, which is important to improve trust in mechanisms generated by machines. This project aims to design a logical framework based on Strategy Logic (SL) for formally verifying and designing mechanisms for social choice. More specifically, we aim at (i) proposing an approach addressing the probabilistic setting (with Bayesian information, stochastic transitions and mixed strategies); (ii) identifying fragments of SL that enjoy both good complexity and satisfying expressive power for being applied to classes of mechanisms; (iii) modeling and reasoning about relevant problems from the state-of-the-art in computational social choice using the proposed logical framework; and (iv) methodically studying the obtained fragments in relation to the expressivity, model-checking and satisfiability problems.

Keywords: strategic reasoning,logics for multi agent systems,mechanism design,social choice,formal methods,model checking,synthesis
DOCtoral training programme in Functional Advanced Materials: Towards a Better Future (DOCFAM-PLUS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Spain,France,Germany,Sweden,Italy,Switzerland
Call: MSCA COFUND 2021 (HORIZON-MSCA-2021-COFUND-01, 2021)
Start date: 2023-03-01
End date: 2028-02-29
Duration (months): 60.0
Total project cost (EUR): 2620800.0
EU funding (EUR): 2620800.0
Participants: 17
Project status: SIGNED

DOCFAM+ (DOCtoral training programme in Functional Advanced Materials: Towards a Better Future) is a new excellent doctoral programme for the recruitment of 26 excellent doctoral researchers led by CSIC through ICMAB. It builds on the success and positive outcomes from the original DOCFAM programme by providing a new dimension through highly interdisciplinary and intersectoral research while fulfilling all the principles of Open Science and maintaining the highest research quality standards. The new programme includes the participation of 6 implementing partner organisations: ALBA Synchrotron Lightsource (ALBA-CELLS), Catalan Institute of Nanoscience & Nanotechnology (ICN2), Catalonia Energy Research Institute (IREC), High Energy Physics Institute (IFAE), the Institute of Microelectronics of Barcelona (IMB-CNM-CSIC) and the Autonomous University of Barcelona (UAB). DOCFAM+ involves a wide variety of research projects & hosting supervisors within the functional advanced materials sector, targeting three main applications in alignment with major European societal challenges: Clean & Secure Energy, Smart Nanomedicine and Sustainable & Low-Cost Electronics. It goes one step further by strengthening the collaborative approach of DOCFAM while enhancing the potential and future career perspectives of recruited fellows and consolidating the excellence and outstanding track-record of participating entities. The frontier research programme will be complemented with advanced training aspects through an integrating holistic approach to the training of doctoral fellows through a combination of research-oriented and demanding soft skills, in alignment with excellence in HR policies, the European Charter for Researchers & the Code of Conduct. The international & intersectoral aspects of the programme are boosted by the collaboration with several associated partner organisations, including start-ups, universities, research & technology organisations and synchrotron installations.

Keywords: clean and secure energy,smart nanomedicine,sustainable and low cost electronics,international and interesectorial doctoral programme
Fluorine-free mAterialS for susTainable-by-design electrolysis Cells towards the H2-bAsed New Generation of clean Energy technologies (FASTCH2ANGE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Research and Innovation actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: Italy,Finland,Spain,Germany
Call: Development of non-fluorinated components for fuel cells and electrolysers (HORIZON-JTI-CLEANH2-2024, 2024)
Start date: 2025-03-01
End date: 2028-02-29
Duration (months): 36.0
Total project cost (EUR): 3564233.15
EU funding (EUR): 2998628.42
Participants: 7
Project status: SIGNED

FASTCH2ANGE aims to pioneer a sustainable-by-design method for developing TRL4-compliant 100% PFAS-free proton exchange membrane-based electrolysis (PEMEL) cells. It will focus on developing four fluorine-free components: proton exchange membranes, catalyst-supporting layers, transport and gas diffusion layers, and new sealing components like gaskets and insulation plates. FASTCH2ANGE will achieve this by designing, developing, and testing new PFAS-free PEMs at TRL4. These PEMs will be made using TEOS-based hybrid organic-inorganic ionomers, targeting an operating current density of 3.0 A/cm² at 1.8 V cell voltage, with a degradation rate under 5 μV/hr by 2030. Innovations in catalyst coating technologies will be explored, including an optimized ink deposition technique. Additionally, fluoroelastomers-free liquid-gas diffusion layers will be prepared using a sol-gel process with silicon alkoxides to improve hydrophobicity and thermal stability. FASTCH2ANGE also plans to develop PFAS-free sealing components using silicon-based sol-gel formulations and advanced materials like stainless steel, polyetheretherketone, and polyphenylene sulfide, employing high-performance coatings such as diamond-like carbon and ceramic. Hence, an advanced testing platform utilizing multisingle cells proprietary technology will test the newly developed catalyst-coated membranes (CCMs), achieving a first-of-its-kind PFAS-free 5-cells stack with optimal components. Harmonized European testing protocols will be used, and the cross-integrability with fuel cell technologies will be assessed in close synergy with SUSTAINCELL and EVERYWH2ERE projects. FASTCH2ANGE new components will allow the replacement of 10-11% by weight of a new generation of electrolysis systems with harmless materials, that for the envisioned European 140 GW capacity would mean saving up to 10500 tons of PFAS crafted into PEMEL components by 2030.

Keywords: electrolysis pfas free pem ccm testing protocols pemel
Textile Recycling EXcellence (T-REX)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Circular economy and bioeconomy sectors
Action type: Innovation actions
Countries involved: Germany,France,Netherlands,Finland,Austria,Switzerland,Italy,Spain
Call: Increasing the circularity in textiles, plastics and/or electronics value chains (HORIZON-CL6-2021-CIRCBIO-01, 2021)
Start date: 2022-06-01
End date: 2025-05-31
Duration (months): 36.0
Total project cost (EUR): 8415570.0
EU funding (EUR): 6385883.26
Participants: 18
Project status: SIGNED

The global consumption of textiles is increasing, with global production of the two most relevant fibres, cotton and polyester, expected to grow by 40% before 2023. There is also no EU-wide plan on how to deal with the existing and anticipated textile waste: currently less than 1% of the material used to produce clothing is recycled into new clothing in a closed-loop process while 87% is landfilled or incinerated. By January 2025 new EU Directive 2018/851 will require all member states to establish a separate household textile waste collection and respect increasing minimum recycling goals, but the pure legislative approach cannot alone solve the growing textile waste problem. Based on estimates from experts, we see that 1% of textile waste entering closed loops leads to 100B euros market loss each year. If a 30% recycling rate is reached (similar to average plastic packaging recycling rates), we will be able to valorize a 30 billion euros/year market. The ambition of T-REX is to contribute to a paradigm shift from household textile waste into desired feedstock. Moreover, we aim to demonstrate that this new commodity and the business models based on it can be completely implemented within the EU. By involving major players across the whole value chain, we aim to demonstrate that a new ecosystem approach, with harmonized methods and quality criteria, can lead to a better understanding of our current textile waste and therefore better upcycling rates into new garments. We also intend to demonstrate that such products can appeal to consumers while at the same time be designed for further recycling. Our goal is to reduce CO2 emissions by 30% across the complete value chain by 2030 by helping to end plastic waste. This project will arm the EU with a commercially viable option to tackle the textile waste and the environmental problems it causes, whilst offering new fields to explore for EU businesses, new know-how for our citizens and, new workforces for the future.
Synchronised Politics: Multiple Times and Political Power (SYNCPOL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2495475.0
EU funding (EUR): 2495475.0
Participants: 1
Project status: SIGNED

Democratic policy-makers in Europe’s multi-level system grapple with multiple times, since different levels of government, parliaments and administrative agencies follow distinct time rules and time preferences. Time clashes are an ever-present threat. Synchronisation is, therefore, a critical, but very little understood dimension of public policy-making. It is designed to avoid systematic time clashes by structuring the timing, speed, frequencies, sequences, durations and time horizons in policy-making. Over the past decade, simultaneous demands for “faster action”, “more time” and “extended time horizons” have pushed multi-level synchronisation in opposing directions. In light of major contestation around synchronisation, SYNCPOL asks: 1) What happens when political demands for “faster action”, “more time” and “extended time horizons” challenge synchronisation arrangements in multi-level policy domains? 2) How does the reshaping of synchronisation arrangements alter the vertical and horizontal distribution of political power amongst governments, parliaments and administrative agencies and the types of power in Europe’s multi-level system? Drawing on institutionalist theory, SYNCPOL conceptualises synchronisation arrangements as a critical variable that is fundamental to the distribution of political power amongst policy-makers. It rigorously probes hypotheses on this crucial connection employing a mixed-methods design that combines document analysis, interviews, a major survey, dictionary-based text analysis and process tracing. The project examines synchronisation across EU, national and subnational governments, parliaments and administrative agencies, with a focus on six multi-level democracies: Austria, Belgium, France, Germany, Italy, Spain. The analysis covers two policy domains - migration-asylum and public health policy – since the early 2010s. SYNCPOL will generate fundamentally new insights into how time shapes democratic multi-level politics and policy.

Keywords: political science time and politics synchronization multi level system public policy
Safer and More Reliable WBG/UWBG-Based MVDC Power Converters (SAFEPOWER)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Spain,United Kingdom,France,Latvia,Italy
Call: Condition & Health Monitoring in Power Electronics (PE) - Wide Band Gap PE for the energy sector (HORIZON-CL5-2024-D3-01, 2024)
Start date: 2024-10-01
End date: 2028-09-30
Duration (months): 48.0
Total project cost (EUR): 4332803.75
EU funding (EUR): 4332803.75
Participants: 10
Project status: SIGNED

Electrification coupled with renewable electricity supply is a key pathway to achieve a deep decarbonization of our society and contribute to an energy transition in a sustainable way. The electric energy demand based on distributed renewable sources is going to be even more important and a more efficient, secure, flexible and affordable energy distribution should be envisaged for the next future. If these requirements are not met, the replacement of well-established solutions based on fossil fuels will be unfeasible. Consequently, apart from the evident environmental impacts, collateral effects could occur, such as great blackouts at national and continental level. In this scenario, SAFEPOWER first explores and investigates on essential digital, enabling, and emerging technologies to achieve a new generation of power converters for solar applications: i) capable of anticipating failures to prevent downtime using effective Condition and Health Monitoring (C&HM) solutions assisted by AI strategies, ii) based on more compactly-packaged, efficient, rugged and affordable Silicon Carbide (SiC) power MOSFETs, diodes and solid-state DC breakers with a more sustainable manufacturing, and iii) prospecting on Ga2O3-based emerging power devices (MESFETs, diodes and solid-state DC breakers) especially designed for this application. Leveraging these technologies, SAFEPOWER studies and proposes new converter topologies and control schemes to enhance their compactness, sustainability, competitiveness, and security. Additionally, these technologies streamline cost-effective maintenance through AI-assisted intervention plans and AI-enabled "limp mode" operation with derating strategies, which can be extended to offshore wind energy conversion. Therefore, the adoption of SAFEPOWER's technological solutions in the EU solar sector not only will establish a competitive advantage against non-EU power converter manufacturers, but also will enable their initial deployment within the EU.

Keywords: mvdc converters,wbg,u wbg,condition and health monitoring,big data analysis,physics of failure
Deep learning derived mechanical biomarkers for cancer therapy prediction (DL-MechanoPredictor)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Cyprus
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-09-01
End date: 2024-02-29
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

In the fight against cancer, it is well recognized that tumors are highly heterogeneous and they might differ considerably not only between tumors types but also among tumors of the same type or even for the same tumor during progression. As a result, the efficacy of standard cancer therapies varies, and while some patients respond to a particular treatment, other patients do not gain any benefit. Consequently, crucial in cancer therapy is the prediction of a patient’s response to treatment. Failure of standard therapies has led to the introduction of a new era of personalized, patient-specific treatments, which are based on the identification of biomarkers that characterize the state of a particular tumor. Many solid tumors (e.g., breast cancers and sarcomas) stiffen as they grow in a host’s normal tissue. Tumor stiffening is a known factor leading to compromised efficacy of therapeutics. Recently, it has been demonstrated by our team and co-workers that repurposing of common drugs with anti-fibrotic properties, known as “mechanotherapeutics”, target tumor stiffness and enhance therapy. Here, we aim to harness the power of deep learning (DL) methods in order to develop a robust biomarker based on ultrasound shear wave elastography (SWE). This biomarker will aim to: (i) predict patient’s response to treatment, separating responders and non-responders and (ii) monitor treatment outcomes, in the case of strategies that target tumor stiffness (i.e., mechanotherapeutics). The DL algorithms will be applied to a large set of existing preclinical data and to additional new data. A proof of concept clinical study on sarcoma patients will accommodate the clinical translation of the biomarker. Furthermore, we propose to develop a software product to be used as a commercial tool for the measurement of the DL-derived, SWE biomarker. A planned market research will highlight the best options for commercialization.
PRodrug technology for Immunotherapy-priming via patient-friendly at-home MEtronomic dosing (PRIME)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2023-10-01
End date: 2025-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Immunotherapy holds great promise for curative cancer treatment. While immune checkpoint inhibitors can induce complete and long-term cures, the percentage of patients responding to immunotherapy remains to be low. Combining immunotherapy with chemotherapeutic drugs that induce immunogenic cell death (ICD) is among the most promising strategies to potentiate antitumor immune responses. Chemotherapeutics are clinically typically administered via intravenous infusion, once every couple of weeks, at high doses. Metronomic dosing is based on the application of chemotherapy drugs at high frequency and low doses, and it is gaining increasing interest to potentiate chemo-immunotherapy responses. However, high-frequency low-dose chemotherapy administration in the clinic via intravenous infusion is pragmatically undoable and economically not feasible. At-home administration via oral ingestion or subcutaneous self-injection is impossible, because of the side effect spectrum of chemotherapeutic drugs. In the PRIME project, we aim to establish PRodrug technology for Immunotherapy-priming via patient-friendly at-home MEtronomic dosing. Prodrugs have assisted in improving drug performance for over a century now, and they are widely employed in pharmaceutical industry and clinical practice, with approximately 10% of new drug approvals technically being prodrugs. We will set out to establish a synthetic and formulation strategy to produce a novel immunogenic prodrug platform, and upon subcutaneous metronomic dosing, we will evaluate the preclinical performance of our prodrugs as monotherapy and in combination with immunotherapy in breast and prostate cancer mouse models. We anticipate that exploiting the technological and socio-economic potential of PRIME will unlock new avenues towards at-home cancer treatment opportunities with enhanced therapeutic outcomes and improved patient quality-of-life.