Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Blueprint for Atlantic-Arctic Agora on cross-sectoral cooperation for restoration of marine and coastal ecosystems and increased climate resilience through transformative innovation (A-AAgora)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Ocean, seas and waters
Destination: Ocean, seas and waters
Action type: Innovation actions
Countries involved: Portugal,France,Germany,Ireland,Finland,Norway,United Kingdom,Romania
Call: Atlantic and Arctic basin lighthouse - restoration of marine and coastal ecosystems and increased climate resilience (HORIZON-MISS-2021-OCEAN-02, 2021)
Start date: 2022-12-01
End date: 2026-05-31
Duration (months): 42.0
Total project cost (EUR): 9778174.76
EU funding (EUR): 8362816.93
Participants: 32
Project status: SIGNED

A-AAgora aims to develop the implementable NbS (Nature based Solutions) through innovative governance structures and technological architecture. It targets to boost resilience to climate change and mitigating its impacts in coastal areas. It identifies synergies by promoting a deliberative process to complement other priority areas within the EC Mission - by setting a Community of Practice and developing a digital knowledge system. It develops NbS at three replicable demonstrators (Demo-PT, Demo-IE, Demo-NO), which can upscaled. The project seeks improved public engagement and enhanced decision-making processes at different political levels based on scientific knowledge and targeted social and economic awareness, using an EBM approach. It builds on the successful implementation of NbS at the Demo’s to which the necessary socio-technological tools will be produced as required for a realistic EBM planning cycle (up to TRL/SRL 7). The Living Lab concept will foster the exchange synergies at multiple scales between researchers and users, decision-makers and local communities, industry and SMEs. A-AAgora will demonstrate that restoration of aquatic ecosystems is possible at a large scale through reduction of pressures, EBM, and effective NbS including blue reforestation to boost coastal resilience to climate change impacts. As well, the A-AAgora will make the most of cross-Mission synergies, by targeting marine ecosystem restoration in coastal communities particularly vulnerable to the risks of sea level rise that urgently need to adapt to ensure their population and infrastructure are safe, climate-proof and weather-resilient. The design of innovative architecture, enabling interoperability with other systems and will also foster a more ‘digital ocean’.

Keywords: living labs transformative hubs ecosystem based management gaming approach socio ecological systems
14 Angstroms Module Integration (14AMI)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: Netherlands,Israel,Austria,Belgium,France,Germany,Switzerland,Romania
Call: General according to ECS-SRIA 2022 (IA) (HORIZON-KDT-JU-2022-1-IA, 2022)
Start date: 2023-05-01
End date: 2026-04-30
Duration (months): 36.0
Total project cost (EUR): 108924981.9
EU funding (EUR): 24954145.0
Participants: 42
Project status: SIGNED

The 14AMI project is about creating technological solutions for the 14 Angstrom CMOS technology node, including a fully integrated functional CFET (Complementary Field Effect Transistor) as new active CMOS device, and state-of-the-art holistic metrology techniques for both wafer and mask inspection and review. All is aimed to keep the pace in the industry to follow “Moore’s law”. The project addresses the following 3 main pillars that are relevant in enabling manufacture of 14A technology, 1) lithography, 2) metrology and 3) process module integration. In lithography the aim is to realize solutions for the 0.55NA EUV scanner platform to secure 14Angstrom node compliance in performance, that is, resolution, alignment, throughput and optics lifetime. In Metrology the objective is to cover wafer and mask metrology and quality control. The aim is to develop holistic metrology, tools & methods and data analytics to improve overlay, CD and focus measurement and quality control with a Precision to Tolerance, P/T, ratio between 0.1 and 0.3. In process module integration work covers the realization and demonstration of a CFET – Complementary Field Effect Transistor - CMOS device. Three options will be investigated for integration; a monolithic, sequential and a hybrid solution. In addition, the partners will develop a PFAS-free photo resist to reduce the ecological footprint of photolithography processes, and a smart AI based sensor technology to improve vacuum chambers' efficiency and reduce waste. At societal level the expected impact of the 14AMI project will support the partners and their supplier network to stay at the leading edge of high-tech developments, crucial to meet the digitization challenges of the European society. Moreover, 14AMI will “boost industrial competitiveness”, and attract talent in Europe, while enabling new application in areas such as security, communication and enabling of further automation in mobility, health and research.

Keywords: semiconductor,process,lithography,metrology,equipment,nano,angstrom,technology,materials,moore s law,heterogeneous,photonics,system,sustainability
Laser Activated Chemistry of Reactive Intermediates: Direct Observation in the jet (LACRIDO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

The goal of LACRIDO is to lock reactive intermediates of a fast reaction by freezing them through Joules-Thompson expansion in the molecular jet, then precisely determine their three-dimensional (3D) structures by chirped-pulse microwave spectroscopy to capture all species marking the reaction mechanism. LACRIDO comprises two stages. The first stage focuses on the detection of van der Waals complexes of the educts through their 3D structures encoded in the microwave spectra. New results of the lower-risk first stage will pave the way to the higher risk-high gain second stage where reactive intermediates are formed by laser activation; adiabatically frozen and locked in the collision-free zone of the molecular jet where the rotational temperature is close to the absolute zero-point; then captured exploiting the strength of microwave spectroscopy in its specificity of conformation-sensitive detection unrivalled by any other type of spectroscopy and chemical methods. The first reaction chosen as key target is Diels-Alder, one of the most classic and important reactions in chemistry. Backed up by the Hueckel theory, Diels-Alder is theoretically described to be a single-step reaction, but details on the reaction course through the van der Waals complex of the educts have never been demonstrated experimentally and will be explored by LACRIDO, giving the final answer for an old, traditional question. The second experimental stage targets the atmospherically important reaction of isoprene with hydroxyl (OH) radical. Its reaction mechanism is extremely diverse with many steps and possible pathways to different stable products. Though lacking experimental evidence, previous studies proposed that the reaction passes through two radical intermediates, each in a cis and a trans configuration. Capturing these short-lived intermediates and determining their 3D structures would give the decisive proof, directly extracted from experiments, on the reaction paths actually taken.

Keywords: microwave spectroscopy,chirped pulse,rotational spectroscopy
Probing nuclear parton dynamics in Heavy-Ion Collisions with Hard Probes (HIC-HP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 209914.56
EU funding (EUR): 209914.56
Participants: 1
Project status: SIGNED

Perturbative QCD (pQCD) derived from first principles, is used to predict experimental observations involving large momentum transfer, such as high-energy jet productions in proton-proton collisions, and the strong interaction between the jet and the Quark-Gluon Plasma (QGP) medium created in nucleus-nucleus collisions. Recent experimental observations have shown that stronger energy-loss mechanism is at play for jets with large transverse momentum, which current perturbative approaches failed to describe. Utilizing an incoherent approach, I will derive an improved energy-loss mechanism that can provide accurate description of the nuclear modification at large jet momentum, which can restore the predictive power of pQCD and allow us to extract the transport property of the hot nuclear medium. The theory of pQCD also anticipates a saturation phenomenon, whereby the density of gluons tends to arrive at equilibrium between the splitting and recombination of gluon quantum fluctuations as the momentum fraction becomes smaller. Recent theoretical development have mitigated the negativity and instability problem that appears in next-to-leading order calculations of forward jet productions under the Color Glass Condensate framework that takes into account the gluon saturation phenomenon. I will also develop a numerical program which incorporates this new approach to implement saturation effects in order to provide a reliable tool in search of saturation signal in current proton-nucleus collisions. The electromagnetic (EM) properties of the nucleus is also of great interest in ultra-peripheral collision (UPC) physics, where the EM form-factor of the nucleus under the GTMD prescription provides a 5-dimensional Wigner distribution of the nucleus. I will also construct a framework using GTMD approach and recent UPC experimental data to analyse the different quantum effects that appears as the EM background in a nucleus-nucleus collision.

Keywords: quark gluon plasma,jet tomography,gluon saturation,heavy ion collisions,ultra peripheral collisions
Does hybridization facilitate explosive speciation of Lake Baikal amphipods? (HybridSpecLBA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 175920.0
EU funding (EUR): 175920.0
Participants: 1
Project status: CLOSED

The adaptive radiation of amphipods in Lake Baikal has brought forward more than 340 species (20% of the world’s freshwater amphipods), making it one of the largest species flocks after the famous African cichlid radiations, and one of the only large radiations in temperate climates. Despite this iconic status the radiation has not yet been subject to detailed genomic investigation. During my PhD I was able to demonstrate excessive amounts of parallel adaptation among the transcriptomes of species of this adaptive radiation. In this project, I will use genomic approaches to test whether the previous results could be explained by hybridisation and adaptive introgression. These processes have been shown to occur in other adaptive radiations, but their functional role in rapid diversification is still debated. My preliminary results indicate that hybridization between two independent lineages of Baikalian amphipods emerged in the period when fast speciation started. Furthermore, I found intriguing signals of positive selection on introgressed loci. Additional data and specific methodology developed in this project will enable me to disentangle the processes governing speciation in this group. Profiting from strong relevant experience of the host laboratory I will re-analyze available transcriptomic datasets together with newly sequenced genomes. I will map precise directions of hybridization at the phylogenetic tree, describe functional associations of introgressed loci, test selection signatures associated with introgression, and estimate the extent to which repeatable ecomorphological traits are underpinned by "reusable" elements of ancestral genomes. This research has groundbreaking potential in providing a direct test of a potential catalysing role of hybridization in fast speciation in this system.

Keywords: fast speciation,hybridization,evolutionary genomics,lake baikal amphipoda
Linking Infectious disease Front-liners’ control Efforts with central public health authorities in The African Great Lakes Region (GREAT-LIFE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Global Health EDCTP3
Action type: Research and Innovation actions
Partnership: EDCTP3 (JU-JTI)
Countries involved: Denmark,Tanzania, United Republic of,Rwanda,Uganda,United Kingdom,Kenya,Netherlands,Burundi
Call: Genomic epidemiology for surveillance and control of poverty-related and emerging/re-emerging infections in sub-Saharan Africa (HORIZON-JU-GH-EDCTP3-2022-01, 2022)
Start date: 2023-07-01
End date: 2028-06-30
Duration (months): 60.0
Total project cost (EUR): 5207500.0
EU funding (EUR): 5207500.0
Participants: 10
Project status: SIGNED

The African Great Lakes region is one of the most densely populated areas in Africa and also one of the areas globally with the highest biodiversity, and forced or voluntary migrations. Very limited information is available on the prevalence and epidemiology of infectious diseases, especially gastrointestinal diseases and antimicrobial resistance that has been very understudied. Logistically it is difficult to sample and conventionally study infectious diseases in the area and such studies have limited real-time value locally. In this study we will take full advantage of the potential offered by combining field-deployable nanopore sequencing combined with metagenomics and lap-top bioinformatics, to establish frontline sequencing at remote sites and linking this with central sharing of analytic output. Newly developed bioinformatics solutions by us have made it possible to perform simple bioinformatics analyses in real-time using lap-tops and subsequently share the analytic output simply using the mobile net, avoiding the need of transferring large amounts of data and access to high-performance computing. In GREAT-LIFE we will establish sequencing across six countries in the region and use this to study the abundances of AMR in villages and refugee camps. Linking this with spatial and temporal epidemiological data will enable us to identify locally relevant drivers for AMR and provide data for changing empiric treatment and policies. In addition, we will utilize sequencing directly on GI samples to identify the causative agents (and their AMR) both to provide data for policies, but also to provide immediate results for direct patient care in the frontline. We will educate a number of people in the very frontline to utilize field-sequencing and bioinformatics, as well as more advanced bioinformaticians and epidemiologist centrally. The data generated will be linked in real-time through a central hub in Tanzania to public health authorities for actions.

Keywords: antimicrobial resistance,epidemiology
Innovative, locally-driven, multi-actor Organic Food Labs (InnOFoodLabs)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Innovation actions
Countries involved: Belgium,Germany,Italy,Sweden,Spain,Denmark,France,Poland,Slovenia,Czechia,Switzerland
Call: Sustainable organic food innovation labs: reinforcing the entire value chain (HORIZON-CL6-2024-FARM2FORK-02, 2024)
Start date: 2025-09-01
End date: 2029-08-31
Duration (months): 48.0
Total project cost (EUR): 5694133.75
EU funding (EUR): 5499481.75
Participants: 26
Project status: SIGNED

InnOFoodLabs will advance 23 innovations in organic food value chains through 12 Living Labs across 9 European countries and a Community of Practice. By improving organic food processing and distribution, the project aims to transform organic value chains into pillars of local economies. The innovations focus on small-scale food processing, sustainable packaging, farmer-processor connections, and innovative supply and distribution models. Innovation roadmaps will be crafted, outlining activities, targets, and responsibilities, with progress documented in “innovation diaries”. The Community of Practice will facilitate knowledge exchange and capacity building via peer-to-peer exchanges, training, and study visits, operating both nationally and internationally. Sustainability impact assessments will be conducted on selected innovations through tailored assessment frameworks developed by Living Lab members, drawing on established sustainability tools and life cycle assessment. The project will also explore stakeholder attitudes, consumer acceptance, and develop tailormade business models. These efforts will culminate in scaling-out of selected innovations, facilitating their adoption in other regions and settings. Finally, the project’s findings will inform policy recommendations, addressing specific regulations as well as broader support policies. In line with the Farm-to-Fork strategy and the EU Organic Action Plan, the project contributes to the target to achieve a 25% organic farmland share by 2030, recognizing that growth in organic farmland requires parallel increase in consumption and market opportunities for organic farmers. The project will facilitate the shift towards more inclusive food systems, contributing to local innovation and responsible consumption. InnOFoodLabs is a transdisciplinary multi-actor project that engages all relevant stakeholders in the value chain, from farmers, processors, retailers, up to consumers as well as researchers and advisers.

Keywords: multi actor approach,organic short supply chains,community of practice,living labs,consumer engagement
4D bioprinting shape-morphing tissues using phototunable supramolecular hydrogels (morphoPRINT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Ireland
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-05-01
End date: 2028-04-30
Duration (months): 60.0
Total project cost (EUR): 1499906.0
EU funding (EUR): 1499906.0
Participants: 1
Project status: SIGNED

During embryonic development, organs emerge through highly dynamic processes driven by complex shape-transformations that sculpt their final shape, composition, and function. Despite this, existing approaches to organ bioprinting employ static hydrogels that are not capable of supporting morphogenetic shape changes. Further, we lack an understanding of how key morphogenetic forces such as volumetric tissue growth can be leveraged to re-engineer fundamental tissue shape-morphing behaviours such as bending, buckling, bulging, or twisting. These are major barriers preventing the design of bioprinted tissues that undergo shape-transformations essential for their evolution into a functional final form. Recognising this, the goal of morphoPRINT is to develop a dynamic hydrogel platform that can spatially turn “on” or “off” volumetric growth in bioprinted tissues to direct 4D shape-morphing, and to use this platform to re-engineer morphogenetic shape changes that sculpt the tissue into a more mature form. To realise this goal, we propose ground-breaking technological advances to create hydrogels with independent networks of 1) supramolecular crosslinks that support volumetric growth and 2) photoresponsive covalent crosslinks that can be spatially activated to resist volumetric growth. We will use this platform to explore how spatial patterns of volumetric growth can drive tissue bending, buckling, and bulging, which will lead to a new conceptual understanding of the physical principles that drive tissue shape-morphing. We will then apply these principles towards the design of bioprinted heart tubes that undergo embryonic-like looping into an early 4-chamber structure. morphoPRINT will enable, for the first time, bioprinted organs that undergo programmable shape-morphing. This will set the stage for a new horizon in organ-engineering research focused on recapitulating physical aspects of morphogenesis rather than just the end-stage geometrical structure of the organ.

Keywords: bioprinting,hydrogels,tissue engineering