Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
OPTILIFT - offshore lifting and logistics (OptiLift)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Norway
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2017-05-01
End date: 2019-04-30
Duration (months): 24.0
Total project cost (EUR): 2199312.5
EU funding (EUR): 1539518.0
Participants: 1
Project status: CLOSED

The vision of the OptiLift project is to upscale, pilot and commercialise our unique toolset for improved safety, increased efficiency and more environmental friendly offshore lifting and logistics. We will enable annual cost savings of €14.m per offshore rig operator and reduce CO2 emissions with up to 50% compared to current platform supply vessels. We will aid solving the industrial and societal problem of safer and more efficient offshore lifting and logistics - provide a significant contribution to the instalment of Blue Energy as outlined in the Blue Growth Strategy of 2012. The overall objective of the OptiLift Phase 2 project is to address and implement the findings of our SME Phase 1 Feasibility Study (GA#674094) to enable rapid and successful commercialisation of OptiLift. We have outlined a series of Commercialisation Objectives that can be grouped in 3 categories and achieving them will bring us to a wide international market uptake: 1) Technology maturation objectives will optimise OptiLift functionalities prior to piloting at end-user’s facilities. Objective is to raise the TRL of our technology from its current TRL6 to 8 (WP1). 2) Pilot and validation objectives to demonstrate and validate the commercial potential of OptiLift in actual end user operating environments covering both offshore and onshore lifting and logistics operations. The piloting activities will elevate OptiLift from TRL8 to 9 (WP2). 3) Market maturation, communication and innovation management objectives enabling us to successfully bring OptiLift to the market and reach sales traction beyond Phase 2 (WP3-6). Through OptiLift we will significantly boost our growth – quantified as accumulated revenues exceeding €56m for the 5-year post-project (2023) with accumulated operating profit of more than €33.6m and employment growth of at least 63 FTEs. Moreover, we expect to generate €1.31bn in reduced costs for our end-users and reduce CO2 emissions with 200,813 tonnes.

Keywords: sensor fusion,marine transportation,logistics,tracking,computer vision,robot vision,offshore lifting,cranes,oil and gas,energy,wind mill
Violence Elites and Resilience in States Under Stress (VERSUS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-09-01
End date: 2023-05-31
Duration (months): 69.0
Total project cost (EUR): 1999390.0
EU funding (EUR): 1999390.0
Participants: 1
Project status: SIGNED

Political violence affects 2 billion citizens across the developing world. Conflict contributes to political decline, high corruption and poverty, poor social cohesion and low institutional trust. VERSUS represents a new direction in political, geographic and empirical subnational studies of conflict and governance. It determines how violence erupts from political processes in varied environments and examines how common internal and external shocks create new trajectories of governance, violence and potential for political resilience. It argues that political relationships between subnational elites and regimes incentivise political violence in developing states. Through a suite of multi-and-mixed methods including power mapping, extensive elite interviews, Bayesian spatial models and dynamic network innovations, VERSUS creates multiple real-time measures of power distribution across select African, Middle Eastern and Asian states for widespread research and policy use. It has five objectives: to advance a developing paradigm on subnational political architectures and environments over static institutionalism; to generate several measures of comparative political power distributions in developing states that capture the degree and depth of regime and elite relationships; to design and test scenarios to explain how, when and where violence erupts as a strategic function of architectures and environments; to develop and implement novel conflict ‘resilience’ tests of regimes, elites and vulnerable members of society in response to internal and external shocks. This creates a state’s ‘carrying capacity’ for shocks and violence; and finally, to collaborate with development practitioners and civil society to implement new standards for elite transparency, support for human rights and ‘good governance’ outcomes.
Organic actuators as a tool for understanding the tactile sense: toward virtual medical touch (Rachel)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Israel,United States
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-06-01
End date: 2024-05-31
Duration (months): 36.0
Total project cost (EUR): 269998.08
EU funding (EUR): 269998.08
Participants: 2
Project status: SIGNED

The importance of the sense of touch in the biomedical sciences is difficult to overstate. Touch and palpation are critical for a range of clinical diagnostic and surgical procedures. The use of tactile feedback in virtual surgery may accelerate medical training and ultimately lead to superior patient outcomes. Technologies designed to manipulate the sense of touch are termed as “haptics”. In order to enable a future where haptics are used in biomedical devices, there is a need to answer fundamental questions arising from the sense of touch perception of humans, as well as to develop novel and smart materials that can transmit realistic tactile cues. One of the great challenges of existing—“off-the-shelf” —haptic actuators is that they are incapable of recapitulating the feeling of biological structures. In this proposal, I plan to adopt a new experimental paradigm based on organic materials (e.g., conductive polymers and liquid crystal elastomers) as haptic actuators capable of producing realistic tactile cues upon stimuli. In addition, fundamental questions related to the sensitivities and thresholds of human touch perception will be assessed for the first time using these materials in conjunction with psychophysical tests. Employing the expertise of the Lipomi lab in materials science and by collaboration with cognitive scientists, I will shed light on the physical and cognitive mechanisms underlying the perception of touch. This work will establish the design principles of organic actuators that may revolutionize technologies for remote care, such as for communities located in “healthcare deserts”, and wearable devices for physical and cognitive therapy.

Keywords: haptics,stimulus responsive polymers,liquid crystal elastomers,conductive polymers,wearable haptic device,kinesthetic feedback,tactile feedback,human machine interface
Quantitative analysis of Nodal/Lefty-mediated pattern formation (QUANTPATTERN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cellular, Developmental and Regenerative Biology
Panel description: Structure and function of the cell, cell-cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Germany
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-07-01
End date: 2020-06-30
Duration (months): 60.0
Total project cost (EUR): 1499750.0
EU funding (EUR): 1499750.0
Participants: 1
Project status: CLOSED

How an initially homogenous population of cells self-organizes to form patterned embryos and tissues is a long-standing mystery in the field of developmental biology. Understanding such self-organizing processes is of central importance for regenerative medicine and would inform approaches to transform embryonic stem cells into complex multicellular structures for human tissue replacement. The influential reaction-diffusion model postulates that patterns emerge during development under the influence of poorly diffusive activators and highly diffusive inhibitors, and we have recently found biophysical evidence supporting the differential diffusivity of the activator Nodal and its inhibitor Lefty in zebrafish embryos. While we have begun to define the Nodal/Lefty activator-inhibitor pair as a reaction-diffusion system that can transform a uniform field of cells into an embryo, three important questions remain: First, how is the differential diffusivity of activators and inhibitors achieved in living embryos? The molecular weights of activator and inhibitor proteins are too similar to explain the difference in diffusivities. Second, how do reaction-diffusion systems adapt to tissue size? Embryos can vary considerably in size, but the proportions of their body plans are remarkably constant. How reaction-diffusion systems mediate this scale-invariant patterning in vivo is unknown. Third, how do reaction-diffusion systems self-organize? Embryos are often born with maternally provided prepatterns, and it is unknown whether reaction-diffusion systems also form relevant patterns in the absence of such prepatterns. We will address these questions in zebrafish and mouse embryonic stem cells by combining innovative quantitative experimentation and mathematical modeling. This high-risk/high-gain approach will allow us to unravel general principles underlying self-organizing processes and will inform new strategies for human tissue engineering from embryonic stem cells.
The contribution of mycorrhizal fungi to multifunctionality in global drylands (MYFUN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2021-01-07
End date: 2023-01-06
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: CLOSED

Dryland ecosystems are a key terrestrial biome, covering 45% of the Earth´s surface and supporting over 38% of the total global population, but their functioning and the goods and services they provide are vulnerable to global environmental changes such as increasing land use intensity (e.g. grazing pressure) and climate aridification. Mycorrhizal fungi, i.e. obligate plant symbionts colonizing the roots of 90% of all land plants, contribute substantially to dryland biodiversity, to their functioning, and the provision of goods and services by dryland ecosystems. In exchange for plant assimilated carbon, mycorrhizal fungi increase plant nutrient supply, influence soil formation and aggregation, plant defence to herbivory and resistance to drought, among other important processes. Through these mechanisms, they influence plant diversity, multiple ecosystem functions, such as nutrient cycling or biomass production, and likely modulate ecosystem responses to aridity and grazing pressure, which are forecasted to increase in drylands under global environmental change. Mycorrhizal effects depend on environmental conditions and species traits determining the efficiency of the resource exchange between plants and fungi. However, to date little is known about the contribution of mycorrhizal fungi to the diversity and functioning of drylands or to the capacity of drylands to provide multiple functions simultaneously (i.e. multifunctionality). We also do not know how the contribution of mycorrhizal fungi to dryland multifunctionality might change under forecasted global environmental change or depending on the resource economy of the plant community. The MYFUN project aims to fill these gaps in knowledge by assessing the contribution of mycorrhizal fungi to dryland multifunctionality in response to environmental stress (increased aridity, grazing pressure) and plant resource economy.

Keywords: drylands,mycorrhizal fungi,ecosystem functioning,plant functional traits,plant root traits,plant aboveground traits,plant soil interactions,climate change,land use change,aridity,grazing
When Public Health Campaigns Warn You, but Your Friends Like to Drink – Connecting Computational Social Science and Neuroscience to Understand Real-World Health Behavior (TheRealCompetition)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 175572.48
EU funding (EUR): 175572.48
Participants: 1
Project status: CLOSED

Malleable unhealthy behaviors excessively burden global societies. Public health media campaigns could offer cost-effective, large-scale interventions, but affect behavior only minimally. To date, health campaigns are optimized to outperform alternative health campaigns in their effects on behavior (e.g. comparing gain to loss-framed messages). Yet, in real life campaigns face other competitors like campaign-related media and peer-produced content. These sources are amplified by popular social media and thus often presented in close proximity to health campaigns. Each source may favor healthy or unhealthy viewpoints, causing health campaign-consistent or -contradictory updates to an individual’s evaluation of a behavior. Ignoring real-world competitors of public health campaigns is a grave oversight that can reduce or even reverse campaign effects on behavior. I seek to understand and optimize public health campaigns in the context of TheRealCompetition, namely healthy and unhealthy media and peer content on social media. This is non-trivial. Self-reporting media exposure and psychological processes underlying media effects overburdens lay participants who struggle to recall and explain how they integrate multiple competing influences on their behavior. In a game-changing interdisciplinary approach, I connect computational social science and neuroimaging to objectively and unobtrusively quantify daily exposure to campaign-related social media content, and understand the neuropsychological processes that explain campaign effects in the context of other sources of influence. Results offer actionable recommendations for practitioners and ecologically validate basic decision-making models. This action brings my unique dual expertise in media effects and neuroscience to Europe, adds computational social science to my skills, and develops my interdisciplinary team leader skills. I will answer novel questions, broaden collaborations, and significantly accelerate my career.

Keywords: alcohol consumption,public health campaigns,health behaviour,social media,social influence,decision making,automated content analysis,neural value system
Deciphering and Engineering the overlooked but Universal phenomenon of Subpopulations in BIOtechnology (DEUSBIO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-03-01
End date: 2026-02-28
Duration (months): 60.0
Total project cost (EUR): 1499998.0
EU funding (EUR): 1499998.0
Participants: 1
Project status: SIGNED

Microbial bioproduction, despite being considered a paradigmatic sustainable alternative to petroleum-based chemistry, is often limited by low yields and productivities, which prevents commercialisation. It is generally known for all types of cells that genetically identical populations can form metabolically distinct subpopulations. This diversity strongly impairs bioproduction as the presence of low-producer or slow-grower cells reduces overall yields. However, the universal phenomenon of subpopulations emergence has been largely overlooked, especially in biotechnology, due to technical difficulties. Now, thanks to recent developments in single cell technologies, in molecular understanding of microbial communities and in synthetic biology tools, we can begin to address this widespread and impactful biological feature. I propose to explore the emergence of subpopulations in yeast and understand their implications in metabolism and bioproduction using and developing cutting edge synthetic biology tools. I aim to use that knowledge to develop novel engineered strains that lack the presence of undesired subpopulations and then use such homogeneous populations for bioproduction. The homogenised production will be investigated in both, monocultures and microbial communities. In DEUSBIO, I will set up an innovative framework to maximise the biosynthesis of high value molecules, with high potential to overcome current limitations. This project will shed light on the phenomenon of subpopulations, whose relevance goes beyond bioproduction, as for example, it has been associated with the origin of multicellularity. Increasing our knowledge about this matter will also have implications in biomedicine, as cell subpopulations are extremely important in the appearance of antimicrobial resistant, in cancer heterogeneity, and in microbiome complexity.

Keywords: synthetic biology,metabolic engineering,microbial bioproduction,microbial biotechnology,microbial cell factories
Simulation in multiscale physical and biological systems (STIMULATE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Joint Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany,Germany,Germany,Italy,Italy,Israel,Germany,Cyprus,Switzerland,Belgium
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-06-01
End date: 2022-11-30
Duration (months): 54.0
Total project cost (EUR): 3755601.0
EU funding (EUR): 3755601.0
Participants: 14
Project status: SIGNED

Simulation alongside theory and experiment is nowadays considered an integral part of scientific discovery. As computation speeds up and new technologies and instruments improve, data generation in all fields of science is rapidly increasing. As a consequence, researchers face new challenges: Data collection exceeds by far the capacity to validate, analyze, visualize, store, and curate the information contained. Additionally, traditional, single-scale, macroscopic physical models are becoming inadequate for the accuracy requirements of modern physical, biological and engineering applications that involve multiscale phenomena occurring over vastly different scales. Tackling these challenges will transform our approach to research potentially leading to unprecedented data-driven scientific discoveries. The overall goal of STIMULATE is to deliver an innovative interdisciplinary educational and research program in simulation and data science, which educates students to best address the challenges posed by exascale computing and intensive data applications, producing computational science professionals tactically positioned to become leaders in both academia and industry. The project proposes a rigorous network-wide training program and research projects that combine mathematical modeling and algorithms for exascale simulations and data-intensive science with applications in the fields of Computational Fluid Dynamics, Computational Biology and Particle and Nuclear Physics with focus in lattice Quantum Chromodynamics. Students will be seconded to industrial partners that will complement expertise in computer technologies, mathematical modeling and data analytics with hands-on training. Experts from eight degree-awarding institutions, three research centers and three companies are engaged in the project. Each of the fifteen fellows of the program will obtain a single joint Ph.D. degree from three academic institutions.

Keywords: computational fluid dynamics,mathematical modeling and algorithms,lattice qcd,molecular dynamics,applied mathematics
Europe's External Action and the Dual Challenges of Limited Statehood and Contested Orders (EU-LISTCO)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Research and Innovation actions
Countries involved: Italy,Israel,Ukraine,Germany,Spain,Italy,Palestine, State of,Türkiye,Norway,Belgium,Poland,Georgia,France
Call: Shifting global geopolitics and Europe's preparedness for managing risks, mitigation actions and fostering peace (H2020-SC6-ENG-GLOBALLY-2017, 2017)
Start date: 2018-03-01
End date: 2021-04-30
Duration (months): 38.0
Total project cost (EUR): 4989936.75
EU funding (EUR): 4989936.75
Participants: 14
Project status: CLOSED

Two risks characterize the European Union’s (EU) regional and global security environments, 1) areas of limited statehood (ALS) in the EU’s East and South, in which central government authorities are too weak to enforce rules and/or do not control the monopoly over the means of violence; 2) contested orders (CO), in which various actors challenge the rules according to which societies and political systems are and should be organized. EU-LISTCO will investigate, first, under which conditions ALS/CO deteriorate into governance breakdown and violent conflict, turning risks into security threats for Europe. By combining risk scanning and foresight methodologies with comparative case studies, we will identify the tipping points at which risks turn into threats, and how they might be better anticipated. We will also investigate how global and diffuse threats affect tipping points as well as the sources of resilience in ALS/CO that can be leveraged from the outside. Second, EU-LISTCO will investigate how the preparedness of the EU and its member states can be strengthened to anticipate, prevent, and respond to threats of governance breakdown and violent conflict and to foster resilience in ALS/CO. In particular, we will examine the strategies, capacities, and policy instruments of EU institutions and selected member states, with a focus on the provisions of the Lisbon Treaty and the implementation of the EU Global Strategy. A new methodology for knowledge exchange between academia and foreign policy will assist EU-LISTCO to achieve its policy objectives. EU-LISTCO encompasses a unique consortium of universities and think tanks in close cooperation with the European External Action Service as well as the Ministries of Foreign Affairs of France, Germany, and Italy. This knowledge exchange will take place continuously allowing scholars to incorporate concrete policy challenges in their research and enabling policy practitioners to pursue research-based policies.

Keywords: areas of limited statehood,contested orders,eu preparedness,security threats,resilience,eu external action,eu global strategy,member states foreign policy