Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Towards a Systematic Theory of Aristotelian Diagrams in Logical Geometry (STARTDIALOG)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1437776.25
EU funding (EUR): 1437776.0
Participants: 1
Project status: SIGNED

Aristotelian diagrams, such as the square of opposition, have been widely used throughout the history of philosophy and logic. Nowadays, they also have several applications in other disciplines that are concerned with logical reasoning, such as psychology, linguistics and computer science. However, many of the applications of Aristotelian diagrams suffer from substantial problems, often due to a lack of understanding of the intricate logical properties of these diagrams. Consequently, the tremendous heuristic potential of Aristotelian diagrams has remained vastly underappreciated thus far. The overarching goal of the STARTDIALOG project is to develop a unified theory of Aristotelian diagrams. We will use a radically new research strategy to accomplish this goal, viz. developing a systematic typology of Aristotelian diagrams in close interplay with a comprehensive diagram database. This empirically informed typology will systematically organize all our (existing and new) knowledge about Aristotelian diagrams, similarly to the role of Mendeleev's periodic table of the elements in chemistry. This will enable us to clarify and solve many of the issues that currently surround the applications of these diagrams, and thereby lead to a more accurate understanding of their methodological importance. This unified theory will allow us to move beyond the specific details of any given application, and to study Aristotelian diagrams as objects of independent interest. This will constitute a major breakthrough in logical geometry, i.e. the theoretical investigation of Aristotelian diagrams. However, because of the widely interdisciplinary use of these diagrams, the scientific impact of the STARTDIALOG project will reach far beyond the boundaries of logical geometry: its results will be relevant for other philosophical logicians as well, for philosophers in general, and ultimately, for all researchers who make use of Aristotelian diagrams in their research on logical reasoning.

Keywords: logical geometry,square of opposition,history of logic,aristotelian diagrams in knowledge representation
AN IMMUNOASSAY-BASED POINT OF CARE TEST KIT FOR RAPID, INEXPENSIVE AND EFFORTLESS DETECTION OF URINARY TRACT INFECTIONS (RAPID UTI)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Türkiye
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-07-01
End date: 2024-06-30
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Urinary Tract Infection (UTI) is the most common infectious disease seen in humans. Also, UTI ranks as the Number 1 infection that leads to a prescription of antibiotics. Just in 2019, 404,6 million different UTI cases emerged worldwide that costed tens of billions of euros to economies and caused around 236.000 deaths. Luckily, UTIs can be cured effectively with right treatment. The problems need to be resolved are: diagnosing of UTI takes a long time (2-7 days), requires expertise and is costly; high false positive rates and contamination risk causes unnecessary laboratory costs and workload; empirical treatment given without waiting for long culture results leads to unnecessary and/or wrong antibiotic usage and consequently to antibiotic resistance. As Nanomed Diagnostic, we developed an immunoassay-based point of care test kit for rapid, inexpensive and effortless detection of UTIs (RAPID UTI). It can diagnose UTI just in 5 minutes. It provides at least 10 times less cost for diagnosis by eliminating several technical processes and costly equipment and consumable investments. It eliminates all unnecessary laboratory costs and workload caused by false-positives and contaminated samples. It prevents unnecessary or wrong antibiotic usage and the bacteria to develop resistance to antibiotics. Within the scope of the 12-month planned project, meetings will be held with European potential customers and distributors, samples will be sent, improvements will be made according to the feedback received, certification studies will be completed, product promotion will be made by participating in fairs, exhibitions and conferences, printed and digital marketing materials will be prepared, and a clinical trial will be conducted in an EU origin institution.

Keywords: infectious diseases,urinary tract infection,uti,diagnosis
Should we prohibit luxury emissions of greenhouse gases, on top of price constraints? (PROHIBLUX)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-02-01
End date: 2026-01-31
Duration (months): 24.0
Total project cost (EUR): 191760.0
EU funding (EUR): 191760.0
Participants: 1
Project status: SIGNED

Many share the intuition that the luxury emissions of the global top 1% are morally wrong, given the current state of the climate crisis. Yet, the subsistence/luxury distinction has been used so far to justify a right to subsistence emissions, rather than a ban on luxury and extravagant emissions. PROHIBLUX aims to develop a carbon-limits theory of emission-permits distribution, i.e. an ethical theory that clearly identifies luxury emissions, indipendently of subsistence emissions, and justifies their proibition. PROHIBLUX research is developed in three stages. First, the candidate will analyse three possible ethical arguments that can support the carbon-limits claim: the axiological argument, the image-externality argument, and the moral-corruption argument. Each argument will be tested against two main objections: the offsetting objection and the coercion objection. Second, the candidate will provide identification criteria for carbon limits, based on the ethical arguments that pass the objections test, and he will address any mismatch by devising an integrated grid of identification criteria. Third, the candidate will lead an ethics-and-policy analysis of different implementation policies of carbon limits, taking also into account the risk of luxury carbon leakage: a ban, a luxury carbon tax and a no-trade individual cap. Through the training program, the candidate will qualify as a researcher at the intersection of ethics and climate policies and acquire new skills related to income and funding generation, project management, student supervision and scientific communication. PROHIBLUX will contribute to the philosophical debate on climate change, proposing a new critique of carbon inequality as an alternative to egalitarian, utilitarian and subsistence-based arguments. PROHIBLUX will contribute to a fair and inclusive transition by developing policy-ready guidelines for the just implementation of carbon limits.

Keywords: luxury emissions carbon pricing fair limits climate mitigation carbon inequality
Refugees’ Political Participation and State-(Re)Making in Displacement (RESTATE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

In today’s world, the majority of refugees originate from states plagued by civil war and extreme violence, where the legitimacy of the state as guarantor of protection is unsettled. Furthermore, refugees often find themselves subjected to various forms of violence at the hands of state actors in host states – regardless of whether they seek refuge in authoritarian or democratic ones. Yet, little is known about how refugees perceive and engage with the state throughout their displacement journeys, and how these perceptions shape their roles as political actors: How do they experience and perceive the state, and in the context of state-inflicted violence in particular, before, during and after displacement? How do these perceptions and experiences affect their political participation? Centring refugees’ political agency, the RESTATE project aims to: (1) provide a dynamic understanding of refugees’ experiences and interactions with the state along their displacement journeys; (2) discern which forms of state violence, both within refugees’ origin and host states, erode trust in state institutions and potentially incite political resistance; (3) theorise the conditions of refugees’ political participation throughout their displacement trajectories; and (4) theorise the implications of refugees’ political participation in both origin and host states for processes of ‘state-making’ – attempts to fulfil key government functions such as protection, justice, the provision of basic services and mobility control. Employing a novel comparative mixed-methods and multi-sited approach, the project studies displacement from three civil-war states (Afghanistan, South Sudan and Syria) in four major host states (Iran, Turkey, Uganda, and Germany) for innovative theory-building on refugees’ political agency in state-(re)making. The empirical knowledge gained will critically inform possible avenues for peacebuilding, conflict resolution and political inclusion.

Keywords: state making,refugees,state violence,political participation
Impact of microplastics originating from formula preparation on protein digestion in infant digestion models (Microprot)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Serbia
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-02, 2022)
Start date: 2023-04-01
End date: 2025-03-31
Duration (months): 24.0
Total project cost (EUR): 140187.84
EU funding (EUR): 140187.84
Participants: 1
Project status: CLOSED

Microplastics (MPs) of various morphologies ranging from 1 µm - 5.0 mm in size have been ubiquitously detected in the environment, food, drinking water, and biota and may pose a threat to food safety, and human health. The highest reported concentration of MPs comes from the processing of foods in plastic packaging. MPs exposure to humans is more prevalent in infants than in any other age group due to the use of polypropylene (PP) based products in formula preparation. The difference in food intake and digestive physiology between infants and adults have been indicated as key contributors to the distinct patterns of proteolysis. In spite of MPs being frequently consumed with food proteins, data on the digestion process of cow’s milk in the presence of MPs are not available. The broad aim of the proposal is to investigate the effect of MPs from plastic packaging material on the digestibility of proteins in adults and infants. The project will focus on specific objectives: comparative digestibility of cow’s milk proteins in the presence of MPs (and aged MPs) in adult and infant digestion models; digestion of infant formulas in the presence of MPs in infant digestion models. The proposed study will use methodology applied in prior research and harmonised protocols for adult and infant digestion. To achieve the proposed aims, the researcher will get training through know-how transfer and research in digestion models, protein analysis, and digestomics from the University of Belgrade, Faculty of Chemistry and get knowledge on MPs preparation and characterization during the short visit to Maastricht University Polymer Department. The proposed project aims to study an issue that has attracted global attention and therefore, the communication and dissemination measures will be oriented both to the scientific society and the wider public. The project will generate new knowledge on the impact of MPs on human nutrition and provide data that may be adopted by policymakers.

Keywords: microplastics,protein digestion,adult and infant digestion models,infant formula,food packaging
Dark Matter Cusps and Cores by Violent Relaxation (CuspCore)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Israel
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-05-01
End date: 2025-05-31
Duration (months): 25.0
Total project cost (EUR): 200538.24
EU funding (EUR): 200538.24
Participants: 1
Project status: CLOSED

We address both the long-standing puzzle of the origin of a universal cusp in dark-matter (DM) halos and the challenge introduced by new observational indications for a dearth of central DM and flat cores in a certain fraction of the galaxies. Such DM-deficient cores are reported both in massive galaxies at high redshifts and in dwarf galaxies, contrary to the expectations for a cusp based on current simulations within the standard LCDM cosmological scenario. We propose to better understand the structural evolution of DM halos in response to drastic mass changes and the gravitational interplay between the DM and the baryons, including inflows, mergers, tidal effects, and outflows. For this, we will develop our analytic model, CuspCore, which would provide a unified framework for following the violent relaxation of a halo after it has been perturbed from an equilibrium configuration. Utilizing this framework, we will work out a scenario for DM-deficient cores in high-z massive galaxies via DM "heating" by dynamical friction on compact merging satellites followed by DM expansion in response to AGN-driven outflows. The same framework will serve to generate cores in dwarf galaxies via supernova feedback and tidal stripping. Finally, we will attempt to use this framework to understand the original universal cuspy profile of DM halos based on non-adiabatic growth. Success in modeling the violent-relaxation process in these circumstances will be crucial for meeting the immediate challenges to the standard cosmological model, and it promises a general impact on other broad applications of galactic dynamics.

Keywords: galactic dynamics
Redox-mediated hybrid zinc-air flow batteries for more resilient integrated power systems (ReZilient)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Norway,Denmark,Portugal,Netherlands,Finland,Belgium
Call: EIC Pathfinder Challenge: Mid to long term and systems integrated energy storage (HORIZON-EIC-2022-PATHFINDERCHALLENGES-01, 2022)
Start date: 2023-10-01
End date: 2027-09-30
Duration (months): 48.0
Total project cost (EUR): 3998856.25
EU funding (EUR): 3998856.25
Participants: 11
Project status: SIGNED

The penetration of renewable energies into the electric grid increases the demand for energy storage to ensure reliable power supply, grid resiliency, and cost reductions. Long-duration and long-term energy storage (LDES and LTES) can bridge the intermittency of renewable sources and reduce the risks incurred by diminished fossil-fuel baseload generation. Electrochemical energy storage (EES), or Li-ion batteries (LIBs), are considered for short-duration energy storage (4-6 hours). When talking about seasonal storage, hydrogen storage is usually the preferable option. The goal of ReZilient is to fill the gap between short-term EES and long-term hydrogen storage by developing and demonstrating at lab-scale (0.5-1.5kW/6kWh) a completely new Zn-air flow battery technology. The estimated capital cost for large-scale deployment is approximately 80 €/kWh, with a levelized-cost-of-storage <0.5 €/kWh/cycle (based on 100 kW/1000 kWh system, 1 week discharge duration). A disruptive redox-mediated strategy for enhanced charge transfer processes is employed with the goal of confining the Zn/Zn2+ redox reaction in the negative reservoir (filled with a semi-solid zinc solution) and eliminating the electroplating process inside the cell (no dendrites) to improve battery lifetime. This will allow discharge times beyond days, contrary to conventional zinc-based batteries where long discharge is hampered by the formation of a cm-thick zinc anode. If successful, the technology has disruptive potential in terms of both extremely low levelized-cost-of-storage, extended storage time, recyclability, and use of non-critical-raw-materials. A pilot concept design of the cell will be conceived after demonstration of the technology. The output of this design will lead to an update of the business case of the distribution network operators and potential customers

Keywords: mid to long duration energy storage flow batteries metal air batteries
Improved SoiL-cable Interaction mooriNG simulaTiONs (ISLINGTON)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark,Spain,Sweden
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-12-01
End date: 2024-11-30
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 3
Project status: CLOSED

Moorings of floating oil and gas (O&G) structures exhibit surprisingly large failure rates. In the O&G industry this problem is simply handled by redundancy in the design. It is unlikely that marine renewables - in order to obtain a competitive levelised cost of energy (LCOE) can afford such redundancy in the mooring design. ISLINGTON has the overall objective to reduce uncertainties in estimated fatigue damage of mooring cables due to soil-cable interaction in the touch down zone (TDZ); and subsequently lower the economic cost of mooring systems for marine renewables. To achieve this objective, the following research actions will be carried out: 1) Improving the numerical modelling of the cable-soil interaction in the TDZ for mooring cables by allowing for time-dependent granular soil dynamics. This will be done by creating an Application Programming Interface (API) inside a granular particle soil solver to allow a two-way coupling to a mooring cable solver providing position and motion of the mooring cable. 2) Generating experimental data for mooring line trenching to be used for validation. This will be done by forced oscillations of a cable in a wave flume with sandy bottom and log the development of the trenching under different forcing. 3) Numerical investigation of the effect of trenching on fatigue of mooring cables. This will be done for standard test cases such as the IAE Task 30: OC3-OC6 test cases. The work proposed is well beyond state-of-art with respect to ground modelling of mooring cables in that the bathymetry will be time-dependent so trenching will be modelled together with the nonlinear cable response. The work on trenching effect to mooring line fatigue and snap load generation and dissipation will be the first such investigation. The resulting papers, models and experimental datasets will be released open-access in line with the open science practice.

Keywords: mooring,cable,finite element method,granular soil,multi physics dynamics,fatigue,damage,hydrodynamics,renewable energy,offshore wind
Understanding Gene ENvironment Interaction in ALcohol-related hepatocellular carcinoma (GENIAL)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Cancer
Destination: Cancer
Action type: Research and Innovation actions
Countries involved: Belgium,France,Portugal,Italy,Sweden,Switzerland,Germany
Call: Better understanding of the impact of risk factors and health determinants on the development and progression of cancer (HORIZON-MISS-2021-CANCER-02, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 11996753.01
EU funding (EUR): 11996753.0
Participants: 15
Project status: SIGNED

Alcohol-related hepatocellular carcinoma (ALD-HCC) is, in Europe, the leading cause of liver cancer (2nd most common cause of cancer-related death worldwide, affecting both men and women). ALD-HCC has a median 5-year survival rate of 15%. Yet, the prognosis is driven by the tumour stage, with curative options providing a 5-year survival exceeding 70% for early-stage HCC (<20% of cases). Therefore, interventions aiming to improve prevention and early detection are key. ALD-HCC results from the interplay between environmental determinants and genetic variations. A comprehensive characterisation of environmental factors (e.g. diet, lifestyle) linked to ALD-HCC is still lacking. We recently performed the 1st genome-wide association study of ALD-HCC and identified predisposing genetic variations. However, their role on alcohol-related liver carcinogenesis needs clarification and the genetic architecture of ALD-HCC remains mostly unknown. GENIAL brings together partners with unique expertise in clinical hepatology, single-cell and spatial multi-omics, artificial intelligence (AI) and communication and dissemination capacities. Our aim is to 1) portray genetic and environmental determinants promoting ALD-HCC; 2) evaluate how they interact at cellular level in human samples and preclinical models to get novel insights into liver carcinogenesis, and identify chemopreventive targets; and 3) assess how these determinants modulate the ALD-HCC risk in prospective cohorts of patients included in HCC surveillance programs. Environmental factors will be comprehensively characterised in an ongoing clinical trial designed to evaluate alternative methods for early-stage HCC detection. Finally, AI models, reaching the minimal viable product stage by the end of GENIAL, will be used to integrate genetic and non-genetic information (including digital imaging) to develop novel cost-effective strategies towards prevention and early-stage detection of ALD-HCC in at-risk individuals. This action is part of the Cancer Mission cluster of projects on ‘‘Understanding’.

Keywords: liver cancer environmental determinants genetic epidemiology