Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Handshake Complexes of Chiral Nanoparticles and Proteins (CHIRAL-PRO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Spain,Belgium,United States
Call: ERC SYNERGY GRANTS (ERC-2024-SyG, 2024)
Start date: 2025-04-01
End date: 2031-03-31
Duration (months): 72.0
Total project cost (EUR): 9272460.0
EU funding (EUR): 9272460.0
Participants: 4
Project status: SIGNED

Chirality, or the absence of mirror symmetry, is omnipresent in both biological and abiological forms of matter. Rapid progress has recently been achieved in the synthesis of chiral inorganic nanoparticles (NPs), of great interest because of the giant optical activity observed in individual NPs and their assemblies. Such nanostructures yield chiral features at multiple length scales, resulting in a huge diversity of chiral morphologies. The field is expanding toward connecting chirality across the worlds of nano and bio, linking optical and biological chiral functionalities. However, what is currently hampering real-world applications is the step from intuitive synthesis of chiral nanostructures to a purposeful design for specific interactions with biological components. The main objective of CHIRAL-PRO is to develop a widely applicable methodology to design chiral NPs with exceptional optical activity, for strong and predictable enantioselective interactions with nanoscale biological entities, such as proteins and amyloid fibrils. The fundamental understanding of the role of chirality in the recognition between inorganic and biological chiral structures will be used for the programmed assembly into optically active nanofibers and for case studies in sensing and metamaterials. To reach this ambitious goal, the complementary expertise of all three partners involved will be essential: synthesis and assembly of chiral plasmonic NPs (Liz-Marzán); three-dimensional electron microscopy of NPs, and the visualization of their interactions with biomolecules in liquid (Bals); and self-assembly methods and computational predictions for chiral multiscale interactions (Kotov). In addition to groundbreaking advancements in fundamental research, the high gain of this work can be found in the generation of a toolbox enabling the scientific community to shift from guessing to precise design of chiral nanostructures with predefined properties.

Keywords: nanoparticle synthesis,chirality,metal nanoparticles,nanoplasmonics,nanoparticle assemblies,transmission electron microscopy,electron tomography,predictive machine learning,nanoparticle protein interactions,protein detection
Sustainable methanol fermentation for animal feed revolution (Prometheus)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Slovenia
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2450000.0
EU funding (EUR): 2450000.0
Participants: 1
Project status: SIGNED

The Prometheus project is set to revolutionize animal feed production through an innovative approach that leverages the wide availability of methanol as a feedstock. By transforming methanol into a high-protein biomass via proprietary advanced fermentation processes, Prometheus offers a sustainable, cost-effective, and resilient alternative to traditional feed sources such as soy and fishmeal. Prometheus technology employs ACIES’ proprietary fastest-growing methanol microorganism that efficiently convert methanol into a biomass with a remarkable 77% protein content. Prometheus feed surpasses the nutritional profiles of conventional feeds, offering a superior amino acid composition ideal for both livestock and aquaculture. The emergence of renewable methanol production technologies promises virtually endless methanol production capacity while acting as a carbon sink, aligning with global sustainability goals. Unlike conventional feed production, which relies on crops like soy or on depleted fish stocks, Prometheus' methanol-based approach ensures a stable supply chain and minimizes exposure to environmental uncertainties (such as drought, hail and El Nino), thereby significantly reducing operational risks. Moreover, the technology is non-GMO, addressing consumer and regulatory concerns and making it easier to penetrate markets that are increasingly leaning towards sustainable and ethically produced feeds. Economically, the Prometheus feed production process is designed to be highly efficient. Initial investments in a Prometheus production facility are projected to yield rapid returns due to the low cost of production and the high market value of the feed produced. Overall, Prometheus represents an alternative future feed solution, ready to address the global protein deficit and support food security in an environmentally conscious manner.

Keywords: animal feed,protein,fermentation,methanol
Electrochemical Synthesis of Polycyclic Aromatic Hydrocarbon-Based Films for Advanced Sodium-Ion Battery Anodes (PAHsSIB)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: SIGNED

The project PAHsSIB aims to advance binder-free anode development for battery current collectors, focusing on sustainable sodium-ion batteries (SIBs). It seeks to overcome challenges in SIB anodes by using polycyclic aromatic hydrocarbons (PAHs) via Pulse Reverse Electrodeposition (PRE). The project has four main goals: 1) Develop a scalable PRE method for stable PAH-based films with a yield exceeding 90%, 2) Customize film properties for optimal Na+ storage, 3) Enhance hierarchical PAH film porosity with asphaltene, and 4) Investigate PAH-based films as binder-free SIB anodes and prototyping as a proof-of-concept. PAHsSIB responds to the need for alternative energy storage due to limited Li resources, ethical concerns, and safety issues in LIBs. SIBs, powered by abundant Na resources, offer a responsible solution but require improved electrode materials. Various materials have been explored, including metal alloys/oxides/sulphides and carbon-based materials. "Janus" nanographenes show promise but face properties and synthesis challenges. Hard carbons are crucial anode materials but their microstructure design remains unclear. The project also addresses solid electrolyte interphase formation to enhance SIB performance. PAHsSIB combines synthetic techniques to control PAH-based anode growth overcoming the problems mentioned. Scalable electrochemical techniques and asphaltene waste materials are used to create porous hierarchical PAH-based anodes. It comprises four research work packages: 1) Fine-tuning the PRE method, 2) Designing non-planar PAHs-based films, 3) Creating hierarchical PAHs-based films from asphaltene, 4) Integrating PAHs-based anodes into SIB cell prototypes and evaluating performance. In summary, PAHsSIB addresses challenges in energy storage by developing advanced binder-free SIB anodes and utilizing innovative methods and materials for improved performance (prototype cell: >250 mAh/g, >5000 cycles), scalability, and sustainability in SIBs.

Keywords: polycyclic aromatic hydrocarbons,novel anode materials,electrochemical techniques,waste to energy,sodium ion batteries
European pilot line for beyond 2nm leading edge System-on-Chip leadership (NanoIC)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Research and Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: Belgium,France,Germany,Ireland,Romania,Finland
Call: Pilot line on advanced sub 2nm leading-edge system on chip technology (HORIZON-JU-Chips-2023-RIA-CPL, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 551778479.0
EU funding (EUR): 448006739.89
Participants: 6
Project status: SIGNED

NanoIC will provide Europe with a beyond 2nm leading-edge SoC pilot line for advanced logic, memory and interconnect technologies to strengthen European leadership in advanced technologies development for markets like computing, communication, mobility, energy and health. The objective of NanoIC is to deliver a 300mm pilot line to the entire semiconductor ecosystem to address the challenges defined in the CPL-1 call of the European Chips Act. Technology development will go up to TRL 3-6 for (i) logic Nanosheet (NS, N2, A14, A10) and Complementary FET (CFET, A7 and beyond) device architectures and high-NA EUV; (ii) the advanced memory options Spin Orbit Torque (SOT)-MRAM, embedded DRAM and 3D-DRAM; (iii) advanced electrical and optical interconnects like die-to-wafer hybrid bonding, fine-pitch re-distribution layer technology chiplet enablement, laser die-to-wafer integration on 300mm photonic interposers. Sustainability is a focus area aimed at energy efficiency, reduction of greenhouse gas emission and water usage of the baseline flows, supported by automated tool and process data acquisition. PDKs on NanoIC baselines for academia, startups, SME’s and industry will be supported by a design enablement facility and training. These include design pathfinding PDKs for prototyping and DTCO at the device and circuit level, and system exploration PDKs for prototyping system functionality combining NanoIC and foundry technologies. Dissemination, Exploitation and Communication actions will engage all stakeholders in pan-European collaborations expanding the community of interest for these advanced technologies. The NanoIC pilot line will build on the collaboration of imec, CEA-Leti (France), Fraunhofer-Gesellschaft (FhG, Germany), VTT (Finland), CSSNT (Romania) and Tyndall Institute (Ireland), but will offer many opportunities for projects with the wider R&D community.

Keywords: advanced cmos,beyond 2nm logic,advanced memories,advanced interconnect,optical interconnect,chiplet,semiconductor technology,process development,process design kit,design pathfinding
Digital Autonomy for RISC-V in Europe (Specific Grant Agreement 1) (DARE SGA 1)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: European High Performance Computing
Action type: Research and Innovation actions
Partnership: EUROHPC (JU-JTI)
Countries involved: Spain,Germany,Czechia,Italy,Netherlands,Belgium,Finland,Sweden,Greece,Croatia,Portugal,United Kingdom,France,Poland,Austria
Call: Specific Grant Agreement for the development of European Processor and Accelerators based on RISC-V (HORIZON-EUROHPC-JU-2024-DARE-SGA-04, 2024)
Start date: 2025-03-01
End date: 2028-02-29
Duration (months): 36.0
Total project cost (EUR): 239995859.5
EU funding (EUR): 102262283.43
Participants: 45
Project status: SIGNED

HPC Digital Autonomy with RISC-V in EurHPC Digital Autonomy with RISC-V in Europe (DARE) will address Europe’s deficit in digital autonomy for High Performance Computing and AI, by creating truly European products for European supercomputers for research and industry. The project builds upon the solid research foundation from EPI, EUPILOT, EUPEX, DEEP-SEA, eProcessor, MEEP and related projects, and it takes advantage of the open RISC-V ecosystem, chiplet revolution and open-source software. It is the first phase of the ambitious 6-year plan set out in the DARE FPA proposal, and it defines clear intra- and inter-phase SMART KPIs and success criteria, on the road to European digital autonomy while supporting current and future computing needs. We will develop and tape-out, in advanced technology, three RISC-V-based chiplets: a vector accelerator for high-precision HPC and emerging applications, an AI Processing Unit inference accelerator for HPC AI applications and an HPC-focused European general-purpose processor. These chiplets bring cost and yield advantages by going beyond the reticle size limitations imposed by monolithic chips and they will be integrated in a mix-and-match fashion to build specific systems. DARE uses a carefully selected set of the most significant European HPC and AI applications to drive hardware (HW) and software (SW) activities in a HW/SW co-design scheme, in order to ensure that the project’s HW and SW results meet the requirements of the European HPC and AI communities. It will build a complete SW stack, optimized for DARE HW, that supports these cutting-edge applications. To make rapid progress, SW and HW developments proceed in parallel, leveraging early access to RISC-V hardware emulation and simulation. Finally, the project will elaborate a detailed technical roadmap and pathfinding, defining the major steps and milestones to be followed in the next phase, in order to achieve the goal of next-generation post-exascale EU supercomputers.

Keywords: hardware,chiplet,sip,ai,integration,hpc
Transcriptional adaptation during vertebrate development at the single-cell level (LivAdapt)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: SIGNED

The development of a multicellular organism requires the precise control of gene expression in space and time so that cells adopt their correct identity. However, genetic mutations can alter this complex process. Recently, transcriptional adaptation (TA) has been uncovered as one of the mechanisms underlying genetic compensation in zebrafish, mouse cells in culture, and Caenorhabditis elegans. TA refers to the phenomenon by which mutated genes (often with mRNA-destabilizing mutations) trigger the transcriptional modulation of related genes, called adapting genes. However, little is known about the spatial and temporal characteristics of adapting gene regulation and particularly during the zygotic genome activation. This project aims to decipher when and where TA occurs during early zebrafish development. Using genome engineering followed by live imaging, high-resolution microscopy and quantitative analysis, I will test the hypothesis that TA is regulated in a temporal manner during zygotic genome activation and that there is a specific mode of transcription during the modulation of the adapting genes (i.e., linear/discontinuous). Furthermore, I will investigate the subcellular localization of mutant mRNA degradation as well as the heterogeneity of the TA response between embryonic cells. Finally, I will implement the live imaging of translation in zebrafish embryo to decipher whether the dynamics of translation is involved during the TA/genetic compensation process. Until now, TA has been mostly investigated on pooled populations of cells. Therefore, we lack the understanding of this phenomenon at the single cell level. This project aims to fill this gap and obtain a better understanding of the spatio-temporal characteristics of genetic compensation which aid in the robustness of vertebrate development.

Keywords: zebrafish,transcription,translation,dynamics,spatio temporal
Enhancing Piezoelectric Properties through Compositional and Microstructural Modification of Barium Titanate Films (MoBaFi)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Netherlands,Belgium
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 217076.16
EU funding (EUR): 217076.16
Participants: 2
Project status: SIGNED

The increasing technologization of society, combined with the transition to renewable energy sources, requires materials and architectures that can handle and retrieve large amounts of data on short time scales and with minimal power consumption. As a result, piezoelectric materials have attracted significant research interest. However, lead-free BaTiO3-based piezoelectric materials currently cannot match the performance of traditional lead-based Pb(Zr,Ti)O3 materials. The MoBaFi project aims to address the challenge of enhancing the piezoelectric response and increasing the Curie temperature of lead-free BaTiO3-based materials. Overcoming these challenges is crucial for improving performance and advancing applications. The scientific approach of the MoBoFi project will focus on developing sophisticated compositional and microstructural modifications in BaTiO3-based films, along with an understanding of the relationship between microstructure-property via in situ characterizations. This project facilitates a two-way and transdisciplinary transfer of knowledge between (1) the applicant’s expertise in the chemical solution deposition (CSD) method and ex situ microstructural characterization, (2) the strong expertise of pulsed laser deposition (PLD) method and in situ ferroelectric characterization at the research group of University of Twente (Host, Supervisor Prof. Gertjan Koster), and (new) the applicant’s own trajectory in building expertise in in situ microstructural characterizations. A secondment will take place at two departments of Ghent University (Prof. Klaartje De Buysser and Prof. Stefaan Cottenier) for size-controlled nanocrystal synthesis and computational screening of ABO3 perovskites. This MSCA-PF will certainly contribute to training the applicant in new scientific and transferable skills, enhancing the career perspectives to become an independent and mature researcher in the EU in the near future.

Keywords: chemical solution deposition,nanocomposite,pulsed laser deposition,piezoelectric,in situ measurement
The Afterlives of Development Interventions in Eastern Africa (Kenya, Tanzania, Mozambique) (AfDevLives)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Portugal
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1499745.0
EU funding (EUR): 1499745.0
Participants: 2
Project status: SIGNED

International development involves ideologies and activities ostensibly directed towards the improvement of well-being of populations in the Global South. Mainstream development interventions emphasize forward-looking ideas of progress and advocate for novelty. In so doing, however, the sector is often myopic, as evidenced by countless unintended consequences that stretch beyond interventions' official life cycle. Whether deemed success or failure, such interventions leave behind a long trail of tangible and intangible traces. Project AfDevLives explores how development interventions' representational and material remains are experienced, employed, and re-appropriated by local actors over time, and how such active immanence of the past affects people's life-worlds. It weaves together three temporal gazes: prospective (development's blueprints); retrospective (sediments of the past, shorthanded as interventions' 'afterlives'); and present-time lived experience. Consciously de-centering formal development discourse and temporalities, the project develops and applies a phenomenological framework oriented around embodiment and intertwinement of people, objects, and space. Using an interdisciplinary approach centered on social anthropology, research will be conducted in Kenya, Tanzania, and Mozambique, neighbouring Eastern African countries that are among the highest recipients of development aid and whose past and present balance continuities and ruptures. The project will unfold via an iterative process involving four complementary work packages: Movement, Image, Storytelling, and Synthesis. Working across work packages, countries, and case studies, the project will pursue three categories of objectives: conceptual (methodological toolkit), empirical (based on extensive ethnographic fieldwork), and practical (aimed at the development sector, local heirs of interventions, and the public at large). The project will result in a robust set of outputs.

Keywords: international development,development interventions,afterlives,phenomenology,eastern africa,ruination
Unraveling the ultrafast plasma dynamics giving rise to the measured evolution filamentary structures using high-resolution X-ray Imaging (PLAXI)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Portugal,United States,Spain
Call: ERA Fellowships (HORIZON-WIDERA-2023-TALENTS-02, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 156778.56
EU funding (EUR): 156778.56
Participants: 3
Project status: TERMINATED

Recent progress in Ultra-High Intensity optical laser systems together with the advent of Free Electron Lasers has enabled the possibility to experimentally study hot dense plasmas with unprecedented spatial and temporal resolution. This early state of the plasma is prone to several ultrafast phenomena relevant for astrophysical scenarios – such as Gamma-Ray Bursts - and plasma-based technologies – such as Inertial Fusion Energy. Recently, thanks to the a novel high-resolution X-ray imaging system, an experimental campaign hosted at the Linac Coherent Light Source has resolved for the first time the sub-micron scale plasma filaments originated in the interaction of a high intensity laser with a thin solid target. These results open a unique opportunity to unravel the underlying physical mechanisms behind the formation and evolution of these filaments of relevance to the aforementioned scenarios. The proposed PLasma Advanced X-ray Imaging project will leverage these recent developments with improved diagnostics and the help of advanced numerical simulations that will transform the exploration and quantitave identification of the main physical processes that dictate the onset and non-linear evolution of the relativistic plasma filamentation instability. This project will bring together the fields of advanced X-ray imaging and High Energy Density Physics, and is expected to enable the visualization of ultra-fast processes in solid-density plasmas in a similar way as optical imaging is now-a-days routinely used in underdense plasmas. The outcomes of the PLAXI project will shed light on the extreme processes that control energy transport in gamma-ray bursts and fast igniting plasmas, which so far could only be assessed theoretically, paving the way to new plasma-based applications.

Keywords: plasma instabilities,high energy density physics,laboratory astrophysics,relativistic laser matter interaction