Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
MOVING TOGETHER – reimagining mobility worldwide (MOVING TOGETHER)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Coordination and support actions
Countries involved: Belgium,Portugal,Portugal
Call: Support for dissemination events in the field of Transport Research (H2020-MG-2019-SingleStage-RTD-MOVE, 2019)
Start date: 2019-12-01
End date: 2023-03-31
Duration (months): 40.0
Total project cost (EUR): 699857.5
EU funding (EUR): 699857.5
Participants: 7
Project status: SIGNED

The Transport Research Arena (TRA) Conference is the foremost and leading European Research and Technology Conference on transport and mobility. It brings together people from all over Europe and beyond, to discuss the newest innovations and the future of mobility and transport providing a wide forum for academia, industry, public administration, authorities and transport operators. TRA leverages dialogue and networking between researchers, policy makers, and industry representatives, through the presentation of transport research, innovations and deployment achievements, fostering alignment and cooperation between initiatives funded at regional, national and European level in order to build up policy trends and plans for a common strategical research and innovation agendas. TRA 2022 will be a unique opportunity for the transport sector to face these new challenges and to boost its research and innovation capacity throughout the full innovation cycle, from idea to market, including fundamental research, prototyping, demonstration, pilot activities and business-driven Research & Development, with an overall strategy based on the motto of Moving together – reimagining mobility worldwide. TRA 2022 will take place in Lisbon, a city which has made a name for itself as the venue of world-renowned events in a variety of sectors (including transport, research and innovation) such as the Web Summit, World Conference on Transport Research Society 2010 (WCTR), the International Road Federation 2010 (IRF), opening its doors to visitors from the four corners of the world, vouching for its innate capacity to host high level international events with the uppermost standards of quality and hospitality.

Keywords: transport research arena,research,innovation,development,conference
Researches on the potential conversion of conventional fish farms into organic by establishing a model and good practice guide (ECOFISH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Spain,Egypt,Romania,Romania,United States
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2015-06-01
End date: 2019-05-31
Duration (months): 48.0
Total project cost (EUR): 580500.0
EU funding (EUR): 580500.0
Participants: 6
Project status: CLOSED

The conversion of conventional aquaculture farms in sustainable aquaculture farms help aquaculture businesses to achieve economic viability and competitiveness. Sustainable aquaculture is undoubtedly the management technique that has most contributed to support aquaculture businesses to adopt aqua-environmental measures for protection of the environment, natural resources and landscape. Aquaponics is known as a sustainable production system for plants and fish that combines traditional aquaculture (aquatic livestock), such as fish, crayfish and shrimp with the hydroponics (growing plants in water) in a symbiotic environment. The Aquaponics is a production system where the waste is utilized as nutrients is a system sustainable for the environment, where high-value products on the market are obtained because they are grown with organic nutrients and free of chemicals or pesticides. By this research project, we aim at to improving onboard waste management and reduce the amount of waste disposed of inappropriately. In order to achieve this goal, we have the following objectives: to integrate aquaculture production system with agricultural production system (aquaponics) and to reconcile and achieve social, economic and environmental objectives with processing and marketing action to add more value to end aquaponics products. The project will develop concepts for the next generation of aquaculture production systems which can be used for multiple purposes, including aquaculture, agriculture and social farming. The project originality comes through its multidisciplinary character in the sense that it combines a research team specialized in various fields, whose experience will result in a production platform product, including all necessary technical indicators for developing and interpretation socio-economic of the results obtained.

Keywords: aquaculture,sustainable,fish farms,aquaponic system,natural resources
Investigating Host-Microbial Interactions after Bariatric Surgery (EnteroBariatric)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-08-01
End date: 2025-01-31
Duration (months): 90.0
Total project cost (EUR): 1499091.0
EU funding (EUR): 1499091.0
Participants: 1
Project status: SIGNED

Obesity and related co-morbidities give rise to severe health and socioeconomic problems. Surgical treatment for obesity (bariatric surgery) is remarkably effective in the control of morbid obesity and rapid resolution of Type 2 Diabetes, and the number of such procedures is increasing rapidly in many obesity-prevalent countries. We, and others, have demonstrated that surgical interventions such as Roux-en-Y Gastric Bypass (RYGB) modulates gut hormone levels, induces systemic metabolic changes and results in the shift of the microbiome from Firmicutes to the Proteobacteria phylum. Although the gut microbiota have been implicated in the reduction of adiposity post-surgery, the long-term effect of altered gut microbiota on patients who have undergone RYGB, remains to be studied. Our recent data suggested that microbial activities are highly associated with inflammation and cancer. My research programme aims to investigate the RYGB-specific gut microbiota impacts on host physiology and colon cancer risk. To achieve this goal, I will employ a multidisciplinary approach that combines systems biology techniques with a bottom-up approach. This work will deliver phenotypic and mechanistic characterisation of the interplay between the host and the gut microbiota. The research findings will significantly contribute towards the understanding of fundamental molecular and cellular processes that are key in host and gut microbiota interactions. This will provide knowledge-based evidence of the gut microbial impact on human physiology, and has the potential to unravel novel prevention targets and promote a more thorough healthcare strategy for bariatric patients.
Molecular profiling of Bladder Cancer to support personalized medicine (BioMedBC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-04-01
End date: 2019-03-31
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

BioMedBC Proposal is focused on improving the patient management of Bladder Cancer (BC). BC presents with the highest recurrence rate and the highest associated costs of all cancers. Due to the intrinsic heterogeneity, the investigated drugs in clinical trials, cannot be easily introduced in the clinical practice. Molecular profiles/ biomarkers (BM) with predictive potential are required to enable patient stratification. The BioMedBC proposal aims at the application of systems biology and cross-omics data integration methodologies to achieve: a) the molecular characterization of BC and b) develop signatures to predict the clinical outcome. To achieve these goals, integration of: i) high resolution proteomics datasets (planned to be acquired within BioMedBC), ii) existing datasets that were obtained in previous EU collaborative projects and iii) publicly available transcriptomics data, will be conducted, focusing on the molecular characterization of BC. Emphasis is given on the investigation of disease prognosis. For this purpose, clinical and follow-up data, available from ongoing prospective studies (n=1758), will be utilized for correlation analysis of the molecular profiles/ biomarkers with disease outcome (recurrence, progression and survival). The prognostic value will be confirmed in newly collected samples with emphasis placed on urinary protein/ peptide profiles, as non-invasive urinary markers is of significant added value. The innovation is held on the prognostic BM that can be further used to stratify patients to those that could be benefited by a potential intervention and guide personalized therapy to improve BC patient management. In parallel, BioMedBC aims at expanding upon the current training of the ER, Dr. Maria Frantzi, on transferability of the basic research results to clinically useful products and create strong career prospects for her desired development as an owner of a future SME.

Keywords: omics,systems biology,proteomics,bladder cancer,prognosis
Comparing effectiveness of self-management interventions in 4 high priority chronic diseases in Europe (COMPAR-EU)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Belgium,Greece,Netherlands,Netherlands
Call: Comparing the effectiveness of existing healthcare interventions in the adult population (H2020-SC1-2017-Two-Stage-RTD, 2017)
Start date: 2018-01-01
End date: 2022-12-31
Duration (months): 60.0
Total project cost (EUR): 5998966.25
EU funding (EUR): 5998966.25
Participants: 9
Project status: CLOSED

COMPAR-EU aims to identify, compare, and rank the most effective and cost-effective self-management interventions (SMIs) for adults in Europe within four high-priority chronic conditions: type 2 diabetes, obesity, chronic obstructive pulmonary disease, and heart failure. This project addresses an important gap in current knowledge applying network meta-analysis, an extension of meta-analysis methodology that allows multiple (rather than pairwise) comparisons of intervention effectiveness, to randomised controlled trials (RCTs) that meet the study inclusion criteria. This centralised analysis of an estimated 4000 RCTs will substantially help to overcome current problems associated with the dispersion and duplication of evidence. The work will be based on a validated taxonomy of SMIs and will prioritise outcomes from the patients’ perspective. In addition, a cost-effectiveness of the most effective SMIs will be estimated to provide insights into the economic consequences of adopting SMIs for societies, healthcare budgets, and patients. Contextual factors associated with successful interventions will also be studied. Drawing on our results, we will develop and pilot decision-making tools to facilitate access to evidence-based information on the most effective SMIs to key users through a user-friendly interactive platform. A multiprong strategy for exploitation of the research findings will lead to clear business cases for implementing it in different contexts within the heterogeneous EU health system. The end goal of the project is to have an impact in supporting policy-makers, guideline developers, researchers, industry, professionals and patients to make informed decisions on the identification and implementation of the most suitable SMIs, therefore contributing to the diffusion of the knowledge, healthcare sustainability and equity and promoting EU competitiveness in a globally emerging market.

Keywords: self management,network meta analysis,decision making
Application of peptide screening technology for identification of substrates of the Jumonji-C histone demethylases (RAPID-KDM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom,Japan
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-01
End date: 2018-09-30
Duration (months): 36.0
Total project cost (EUR): 270271.8
EU funding (EUR): 270271.8
Participants: 2
Project status: CLOSED

In recent years it has become evident that the functional human proteome is vastly expanded by post-translational modifications (PTMs) that modify protein function and gene expression in a time- and context-dependent manner. Misregulation of these modifications leads to developmental disorders and often contributes to disease biogenesis. However, with the possible exception of protein phosphorylation, the full roles and regulation of these modifications remain poorly understood. Currently, in particular, arginine methylation is proposed to be largely stable and irreversible. Building on my exciting preliminary data that demonstrate that Jumonji C histone demethylases (JmjC KDMs) can catalyse removal of arginine methylation, this proposal aims to identify biologically relevant methylarginine substrates of the JmjC KDM. Cutting-edge mRNA display-based peptide screening technology will be adapted for use as a substrate identification assay in collaboration with Prof Hiroaki Suga at the University of Tokyo. Consensus sequences identified using this novel methodology will be used to identify biologically relevant peptide sequences by bioinformatic searches. On the return to the UK, results with isolated proteins will be correlated with in-cell studies and the functional consequences of these reactions assessed. Given the high level of interest in the post-translational modification field, the results of this study will be of interest to a very wide-range of scientists including other academic researchers in the field of epigenetics and beyond, and major biotechnology and pharmaceutical companies studying JmjC KDMs as drug targets. The fellowship will provide training in state-of-the-art techniques. The collaboration between the University of Oxford and the University of Tokyo will enhance the research capabilities of the European Union, promote cross-fertilisation of knowledge and strengthen research ties with Japan.

Keywords: enzymology,post translational modifications,histone demethylases
NanoElectronics Roadmap for Europe: Identification and Dissemination (NEREID)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Coordination and support actions
Countries involved: Ireland,Italy,Italy,Germany,Spain,Italy,Germany,Switzerland,Belgium,Finland,France,France
Call: Generic micro- and nano-electronic technologies (H2020-ICT-2015, 2015)
Start date: 2015-11-16
End date: 2018-12-15
Duration (months): 37.0
Total project cost (EUR): 1123000.0
EU funding (EUR): 1000000.0
Participants: 17
Project status: CLOSED

The objective of this project is to elaborate a new roadmap for Nanoelectronics, focused on the requirements of European semiconductor and applications industry, and the advanced concepts developed by Research centers in order to achieve an early identification of promising novel technologies, and cover the R&D needs all along the innovation chain. The final result will be a roadmap for European micro- and nano-electronics, covering all TRL, with a clear identification of short, medium and long term objectives. The roadmap will be divided into main technology sectors and include also cross-functional enabling domains. A proper dissemination of results will take place through the close relationship of the project with the leading European organizations in the field of micro- and nano-electronics, and sanity checks are foreseen during the project with the users’ world.

Keywords: roadmap,semiconductors,cmos,sensors,power,beyond cmos
New Models of Sanctity in Italy (1960s-2010s). A Semiotic Analysis of Norms, Causes of Saints, Hagiography, and Narratives (NeMoSanctI)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Italy
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-03-01
End date: 2024-02-29
Duration (months): 72.0
Total project cost (EUR): 1051590.0
EU funding (EUR): 1051590.0
Participants: 1
Project status: SIGNED

In cultures with a strong Catholic tradition saints represent models of life perfection, dialectically elaborated by a plurality of subjects and expressed in a thick intertextual network. Since the Second Vatican Council (1962-1965), when the Church promoted a policy of adaptation of her tradition to the modern world, the modeling of sanctity has undergone a deep transformation. In a context of global change, new models of sanctity have assumed a central role in guiding the faithful by proposing a renewed religious alternative to growing secularization. NeMoSanctI intends to study how models of sanctity have changed after the Second Vatican Council and their relationship with the culture of a country exemplum of strong Catholicism: Italy. To this end, it will apply a pioneering semiotic method based on the study of values, which will allow the comparative analysis of a corpus of texts of different genres: - normative texts regulating sanctity emanating from the Church; - judicial texts, i.e. causes of canonization of three famous Italian saints (Padre Pio, Gianna Beretta Molla, and Gerardo Maiella), with a focus on the dialectics between the models proposed by laic witnesses and by ecclesiastic inquirers; - narrative texts, i.e. a sample of popular hagiography about the three saints, of official hagiographic collections, and of Italian literary texts, where the theme of sanctity tends to be unconventionally elaborated and dissociated from Catholic values. Despite its relevance for a deeper understanding of the role of religion in today’s culture, a systematic research on new models of sanctity and on their intertextual codification is still missing. By carrying out this research and by proposing an innovative semiotic method for the analysis of models of life perfection, NeMoSanctI will have a significant impact on numerous disciplines, especially semiotics, religious and cultural studies, critical studies of hagiography and canon law, literary and Italian studies.

Keywords: semiotics,italian literature,religious studies,italian studies
Promoting STARTups and SMEs as the BEST place to work through workplace innovation (Start-at-best)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Italy,Ireland,Belgium,Portugal
Call: Workplace innovation uptake by SMEs (H2020-INNOSUP-2019-04, 2019)
Start date: 2019-06-25
End date: 2021-12-24
Duration (months): 30.0
Total project cost (EUR): 299968.75
EU funding (EUR): 299968.75
Participants: 4
Project status: CLOSED

The Start-at-best proposal will be focused in making STARTups and SMEs (small businesses) the BEST place to work, by promoting and fundings small-scale / big-outreach worlplace innovation projects. The proposal is coordinated by the Startup Europe Regions Network, a Brussels based associated born under the auspices of the European Startup Europe Initiative and the Committee of Regions, and that groups several national and regional innovation agencies across Europe, and is directly supported by 3 of these agencies. The project will devote more than 78% of its resources to fund startups, through calls for proposals that will allocate grants of 7,5K€ to a minimum of 30 small businesses in Europe. Our proposal will contribute to making Workplace Innovation easy for SMEs and especially for startups and micro-firms across Europe, by providing financial means to small firms to allow them to experiment new solutions and by developing a strong content basis provided through an easy accessible and clear web site based on an repository of real life, startup-inspired cases that are described in terms of a set of key features and which help to provide answers to companies that are in need for a workplace change. The need and desire to change will be brought to the surface through ways such as workshops, awareness sessions, consulting, etc. Workplace innovation represents a rising tide, but the boats that reach the swell first will be first to succeed. The partners in this proposal are ideally placed to achieve these goals as they include: a leading European association of regional agencies devotes to startup and SME innovation created under the auspices of the Startup Europe EC initiative, the Startup Europe Regions Network (SERN); and 3 regional/national agencies (ASTER, IT, Cork Innovates, IE and ANI, PT) responsible for the management of SME support funds in their regions, and that will enlarge their support to cover workplace innovation projects through this proposal.

Keywords: workplace innovation,employee driven innovation