Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Parallel fluorescence spectroscopy tools for micro and nano-analytical applications down to single biomolecules (PARAFLUO)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Italy,Germany,Germany,United Kingdom,Germany,United Kingdom
Call:  (FP7-SME-2008-1, 2008)
Start date: 2009-06-01
End date: 2011-08-31
Duration (months): 27.0
Total project cost (EUR): 1463749.0
EU funding (EUR): 1133000.0
Participants: 9
Project status: CLOSED

Analytical methods based on fluorescence measurements are widely employed for investigating biological process at cellular level. A modern technique is fluorescence-lifetime imaging microscopy (FLIM), where a map is obtained of the fluorescent emission lifetime versus position in a cell. The objective of project PARAFLUO is an innovative instrumentation system that will enhance and extend the usefulness of FLIM, making possible to obtain simultaneously FLIM data separately for the various spectral components of the emission. There is wide consensus among experimenters that this spectrally resolved technique (called sFLIM) will support a better understanding of the biological processes involved. Such understanding is paramount for the (patho)physiology of tissues and organisms and gives a base for gaining a better insight in key medical issues, such as the origin and growth mechanisms of tumors. The optoelectronic instrumentation developed will be useful also for other market objectives, such as simultaneous multi-spectral profiling of objects by laser detection and ranging (LADAR) techniques. The developments envisaged are essentially: (a) a photon-counting array detector based on the silicon single-photon avalanche diode (SPAD) technology; (b) a new micro-lens system for focusing light onto the detector and (c) an ASIC based multichannel time correlated single photon counting (TCSPC) system, integrated with an optoelectronic setup in a confocal microscope. The base of the PARAFLUO consortium is given by three SME’s; each one having a consolidated technical know-how and an active presence in the market over one of the quoted scientific-technical (S/T) areas. Five RTD performers have been selected primarily because of their high international standard in these areas; furthermore, each of them has experience of active collaboration with the SME directly concerned by the specific S/T work. A professional partner supports the coordinator and ensures timely and efficient exchange of materials and information in the project.

Keywords: fluorescence spectroscopy,time correlated photon counting,fluorescence lifetime imaging,tissue imaging
Reinforcing the networking of FP7 National Contact Points (NCP) and third country contacts in the Euratom Fission Programme (NUCL-EU)

Framework: FP7 — Euratom
Programme: Nuclear fission and radiation protection
Theme: Fission/fusion cross-cutting actions
Destination: Cross-Cutting Actions
Action type: Coordination and support actions
Countries involved: Italy,Poland,South Africa,Czechia,Cyprus,Slovakia,Slovenia
Call:  (FP7-Fission-2008, 2008)
Start date: 2009-10-01
End date: 2013-12-31
Duration (months): 51.0
Total project cost (EUR): 406172.2
EU funding (EUR): 349000.0
Participants: 7
Project status: CLOSED

Research and technology development in the area of nuclear fission and radiation protection – under the Euratom programme – is booming. However, there is a clear need for better coordination of research activities at a European and global level – in order to further stimulate innovation and improve the EU’s competitiveness worldwide. Hence, a well-organised and proficient network of National Contact Points for the Euratom programme is essential to improve this coordination. Project NUCL-EU is a 51months project and has the overall objective to create an efficient, pro-active and sustainable network for stimulating closer cooperation among all the National Contact Points and Third Countries contacts for the Euratom Programme. NUCL-EU has two clear specific objectives: the reinforcement of the Euratom NCP network and the enhancement of Third Countries participation. Principal activities include good practice benchmarking with Euratom NCPs, followed by tailor-made training sessions and twinning schemes for new and less experienced NCPs. Third Countries contacts will be encouraged to participate in all NUCL-EU activities. Participation of research organisations especially from Third Countries in Euratom will be boosted through a large Brokerage Event. The expected impacts of NUCL-EU will be 1) a strong and uniform Euratom NCP network, involving sound communication with Third Countries, and 2) more effective participation of Third Countries to the Euratom programme. Moreover, good practices of this network will be publicly available as a handbook for NCPs in other FP7 themes. The coordinator (APRE) will invite all Euratom NCPs, including those outside the consortium, to the project activities. The currently only Third Country NCP (South Africa) is part of project consortium.

Keywords: coordination network ncp training
Integrated Chemical synthesis and Screening in patient Cells (ICSC)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Spain,United Kingdom,Denmark,Denmark,Israel
Call:  (FP7-SME-2008-1, 2008)
Start date: 2009-03-01
End date: 2011-08-31
Duration (months): 30.0
Total project cost (EUR): 1388534.0
EU funding (EUR): 1056000.0
Participants: 6
Project status: CLOSED

The ICSC project is a “Research for SMEs” focused research project that is to develop an integrated high throughput chemical synthesis and cell-based screening platform for the development of efficacious novel drug candidates without the need for chemical nor cell biological infrastructure. The technology will put early drug discovery in the hands of institutions that have a comprehensive knowledge of disease mechanisms and management of patients. The technological core of the ICSC project is a newly developed high-throughput drug discovery technology ChemoCellomics®, which integrates chemical synthesis and high throughput cell-based screening in a polymer-based format. The ChemoCellomics® technology will in the ICSC project be converted to a bench-top technology where optically encoded micro carriers will hold chemical library member and patient cells. The structural identity of the chemical library member is optically encoded in each carrier. It is expected that the ICSC technology will have a major impact on multiple areas within life sciences in particular drug discovery. Early drug screening and development of drug candidates including synthesis of chemical libraries and high throughput cell-based screening have previously been reserved pharmaceutical- and major biotechnology companies with comprehensive chemistry- and cell biological infrastructure. The philosophy behind the development of the ICSC technology is to provide institutions (hospitals, academia and small biotechnology companies) possessing detailed knowledge about disease mechanisms and patient treatment, with a capability to exploit this knowledge in early drug discovery.

Keywords: chemical synthesis,cell based screening,patient cells,cancer stem cells
Scams and Fraud Detection in Voice over IP Networks (SCAMSTOP)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Germany,France,Portugal,Greece,Norway,Spain
Call:  (FP7-SME-2008-1, 2008)
Start date: 2010-01-01
End date: 2011-12-31
Duration (months): 24.0
Total project cost (EUR): 1507236.0
EU funding (EUR): 1005133.0
Participants: 6
Project status: CLOSED

In traditional telecommunication, various experts estimate that fraud accounts for annual losses at an average of 5% of the operators’ revenue and still increasing at a rate of more than 10% yearly. Hence, with the openness and low cost structure of voice over IP (VoIP) service one can expect an even higher threat of fraud and higher losses of revenue making fraud and misuse of services one of the main challenges to VoIP providers. Fraud detection has been an active research and development area in the world of banking and credit card industry. In the VoIP area, there is still hardly any research or products that can assist providers in detecting anomalous behaviour. To fill in this gap, SCAMSTOP will provide a complete framework/solution for automatic fraud detection that alarms providers when suspicious behaviour is detected. The design of the SCAMSTOP fraud detection tools will be based on two aspects. On the one side, SCAMSTOP will use well known methods for statistical behavioural modelling and anomaly detection that have proven their efficiency in the area of credit card, banking and telecommunication and apply them to Internet telephony services. Of special interest here is characterizing the normal usage behaviour while taking into consideration the offered service plans and service structure. On the other side, innovative approaches based on multi-protocol event correlation that take into account the specific nature of VoIP protocols and components will be developed. This solution will not only be designed to achieve a high detection rate but it will also be optimized to be resource efficient as well. To assess the efficiency and usability of the developed tools and mechanisms, the SCAMSTOP fraud detection system will be intensively tested and probed throughout the project . The consortium is a healthy mixture of SMEs including VoIP service provider, VoIP security and signalling products manufacturers as well as reputed research organizations.

Keywords: fraud detection,scam prevention,voice over ip,sip,artificial intelligence
Monitoring and controlling volatile organic compound (VOC) emissions by using novel on-line FTIR/iPAS technology (ZERO-VOC)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Spain,Finland,Türkiye,Spain,Germany,United Kingdom
Call:  (FP7-SME-2008-1, 2008)
Start date: 2009-11-01
End date: 2012-04-30
Duration (months): 30.0
Total project cost (EUR): 1478138.26
EU funding (EUR): 1111035.2
Participants: 11
Project status: CLOSED

Strict limits have been set for volatile organic compounds (VOC) emissions due to their direct and indirect effects on the environment and the potential risk to human health. Industrial plants using solvents have to limit their emissions to the levels stated in VOC-directive (Directive 99/13/EC) before the end of October 2007, whereby VOC emissions from the solvent using industry should be reduced by 67% compared to the 1990 VOC levels. Furthermore the directive sets very strict limits (in some cases below 1 ppm) for the so called ”R-labeled” VOCs, which contain for example different chlorinated VOCs. In environmental analysis, one of the most challenging and still unresolved needs is the reliable measurement of (VOC). VOC emissions are normally present as mixtures. Furthermore, it is typical for many really harmful VOCs to be present at low concentrations. The emission limits for these compounds are also very low. This poses an enormous challenge in terms of the sampling, measurement and the selection of removal methods. To date, however, no reliable, selective and sensitive measurement technique exists that is capable of identifying the VOC emission levels of certain “R-labelled” VOCs in order to fulfil the limits stipulated by new directives. This project will develop an affordable, reliable tool for on-line monitoring of harmful and toxic VOC emissions. The main focus will be the development of a novel iPAS sampling technique and calibration for online process measurements, which will be applied for its use in several demanding gas measurements (VOC emissions), where the use of traditional measurement techniques have clearly failed, or have proven very difficult and laborious. As a result, reliable emission measurement would form a coherent basis for the development and evaluation of the VOC emission abatement technologies.

Keywords: optical measurement technology
Intelligent Adaptable Surface with Optical Fiber Sensing for Pressure-Tension Relief (IASIS)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Greece,Cyprus,Greece,Germany,United Kingdom
Call:  (FP7-SME-2008-1, 2008)
Start date: 2009-11-10
End date: 2012-01-09
Duration (months): 26.0
Total project cost (EUR): 1495000.0
EU funding (EUR): 1115000.0
Participants: 9
Project status: CLOSED

IASiS addresses pressure ulcer incidence and treatment and aims to develop and demonstrate an Intelligent Adaptable Surface for serving as the skin/machine interface in therapy beds and wheelchair seating systems. This surface is envisaged to be capable of redistributing the pressure, strain and shear applied on the skin. A controller and an algorithm optimizes the load-time curve as pre-specified by the pressure-duration threshold curve, thus protecting the tissues against prolonged and excessive epidermal pressure-shear. This will in turn prevent the onset or deterioration of pressure ulcers. Diagnosis and prevention will rely on intelligent optical fiber sensing devices that can identify the values and coordinates of excessive epidermal loadings and will provide feedback information to an adaptable mattress or seat mechanism. This adaptable mechanism comprises of self-shaping elements and is responsible for relieving pressure and strain in a timely manner according to the information received by the sensing modules. To this end, IASiS intends to develop optical fiber-based two-dimensional pressure/strain/shear sensing elements and demonstrate their performance for the first on rehabilitation applications. It will also integrate the intelligent fiber-based sensing surface with the adaptable surface mechanism, and finally IASiS will evaluate the performance of the developed Intelligent Adaptable Surface through extensive Laboratory as well as Clinical Trials.

Keywords: pressure ulcer diagnosis-prevention-therapy,rehabilitation,biomechanic problems,pressure/shear sensing surface,medical optical pressure/shear sensor,industrial optical pressure/shear sensor
Development of an innovative, cost-effective environmetally friendly closed cage for sea-based fish farming (CLOSEDFISHCAGE)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Norway,Poland,Spain,Italy,Denmark,Denmark,Spain,United Kingdom
Call:  (FP7-SME-2008-1, 2008)
Start date: 2009-09-01
End date: 2011-08-31
Duration (months): 24.0
Total project cost (EUR): 1418536.0
EU funding (EUR): 1110433.0
Participants: 11
Project status: CLOSED

ClosedFishCage will focus on the development of a closed, escape proof, constant volume, sea-based cage for fish farming. Among the project’s innovative elements are a very durable and flexible polymer plastic net pen, a predator guard, a control system, easy set-up and replacement of damaged cage parts. The technological solutions involved in the sea-based cage will preserve advantages of land-based fish farming while at the same time taking advantage of the cost efficiency of seabased fish farming. Furthermore, the new cage system will be both substantially more cost-efficient and also more environmentally friendly existing fish farming technologies. Consequently, ClosedFishCage will result in the development of new, more appropriate technology enabling increased use of sea-based fish farming and thus also greatly improve possibilities of fish farming technology. The market for fish, and especially European farmed fish, continues to grow. However, EU catches have dropped in recent years, aquaculture production has remained stable, and the current supply of fish is therefore not enough to cover market demand. Furthermore, as a result of a combination of near depletion of certain EU fishery stocks, reduced annual catch quotas, and reduced fishing fleets, Member States of the Union are becoming increasingly dependent on imports from third countries. ClosedFishCage will not only improve the competitiveness of SMEs in the aquaculture sector but also safeguard the potential production of good quality fish, in sufficient quantities, at competitive prices.

Keywords: closed cage,fish welfare,cost-effectiveness,environmentally friendly,quality fish,seafood,sea-based.
Autonomous Robot for an Automatic Inspection of Nozzle Welds in Nuclear Environment (NOZZLEINSPECT)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: United Kingdom,Poland,France,Lithuania,Greece,Spain,United Kingdom
Call:  (FP7-SME-2008-1, 2008)
Start date: 2009-07-01
End date: 2011-09-30
Duration (months): 27.0
Total project cost (EUR): 1448003.0
EU funding (EUR): 1104400.0
Participants: 8
Project status: CLOSED

Regular in-service inspection is important to verify the integrity of welded nozzle sections in nuclear and other safety critical facilities. Nozzle sections made from austenitic steel can be susceptible to rapid crack growth due to thermal fatigue and stress corrosion. Early detection of cracks is therefore essential to ensure the continued safe operation of the facility in question. In order to reduce the time and cost of such inspections there is an urgent need to develop a system capable of performing a full inspection of nozzles without the need to change probes. The aim of NozzleInspect project is to design an autonomous robot system that able to: reduce the inspection times, Improve defect delectability and sizing, Reduce human intervention which will reduce workforce radiation uptake and Reduce requirement for robotic manipulation and consequently reduce size and cost of robotic deployment system. The goal of NozzleInspect project is to improve the reliability of the inspection of the welded nozzle sections in nuclear and other safety critical facilities. The robot will carry out a new and novel flexible phased array probe to allow a full inspection of nozzle weld areas and an advanced navigation system that follow the weld in nozzle. The presence of defects in these parts could lead to catastrophic component failure.

Keywords: novel and new flexible phased array probe,signal processing,ultrasonic modelling,navigation system,autonomous robot with vacuum arrangement.
Neural circuits for space representation in the mammalian cortex (CIRCUIT)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Neurosciences and neural disorders
Countries involved: Norway
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-01-01
End date: 2013-12-31
Duration (months): 60.0
Total project cost (EUR): 2499112.0
EU funding (EUR): 2499112.0
Participants: 1
Project status: CLOSED

Neuroscience is one of the fastest-developing areas of science, but it is fair to say that we are still far from understanding how the brain produces subjective experience. For example, simple questions about the origin of thought, imagination, social interaction, or feelings lack even rudimentary answers. We have learnt much about the workings of individual cells and synapses, but psychological phenomena cannot be understood only at this level. These phenomena all emerge from interactions between large numbers of diverse cells in intermingled neural circuits. A major obstacle has been the absence of concepts and tools for investigating neural computation at the circuit level. The aim of this proposal is to combine new transgenic methods for cell type-specific intervention with large-scale multisite single-cell recording to determine how a basic cognitive function self-localization is generated in a functionally well-described mammalian neural circuit. We shall use our recent discovery of entorhinal grid cells as an access ramp. Grid cells fire only when the animal moves through certain locations. For each cell, these locations define a periodic triangular array spanning the whole environment. Grid cells co-exist with other entorhinal cell types encoding head direction, geometric borders, or conjunctions of features. This network is thought to form an essential part of the brain s coordinate system for metric navigation but the detailed wiring, the mechanism of grid formation, and the function of each morphological and functional cell type all remain to be determined. We shall address these open questions by measuring how dynamic spatial representation is affected by transgene-induced activation or inactivation of the individual components of the circuit. The endeavour will pioneer the functional analysis of neural circuits and may, perhaps for the first time, provide us with mechanistic insight into a non-sensory cognitive function in the mammalian cortex.

Keywords: neural circuits,spatial representation,navigation,hippocampus,entorhinal cortex
Prediction of the Effects of Radiation FOr reactor pressure vessel and in-core Materials using multi-scale modelling - 60 years foreseen plant lifetime (PERFORM 60)

Framework: FP7 — Euratom
Programme: Nuclear fission and radiation protection
Theme: Research infrastructure
Destination: Reactor Systems
Action type: Collaborative project
Countries involved: France,Belgium,United Kingdom,Spain,France,Germany,Finland,Czechia,United Kingdom,Germany,United Kingdom,United Kingdom,Spain,Bulgaria
Call:  (FP7-Fission-2008, 2008)
Start date: 2009-03-01
End date: 2013-12-31
Duration (months): 58.0
Total project cost (EUR): 13596130.2
EU funding (EUR): 5985465.0
Participants: 23
Project status: CLOSED

In nuclear power plants, materials may undergo degradation due to severe irradiation conditions that may limit their operational life. Utilities that operate these reactors need to quantify the ageing and the potential degradations of some essential structures of the power plant to ensure safe and reliable plant operation. So far, the material databases needed to take account of these degradations in the design and safe operation of installations mainly rely on long-term irradiation programs in test reactors as well as on mechanical or corrosion testing in specialized hot cells. Continuous progress in the physical understanding of the phenomena involved in irradiation damage and continuous progress in computer sciences have now made possible the development of multi-scale numerical tools able to simulate the effects of irradiation on materials microstructure. A first step towards this goal has been successfully reached through the development of the RPV-2 and Toughness Module numerical tools by the scientific community created around the FP6 PERFECT project. Relying on the existing PERFECT Roadmap, the proposed 4 year Collaborative Project PERFORM 60 has mainly for objective to develop multi-scale tools aimed at predicting the combined effects of irradiation and corrosion on internals (austenitic stainless steels) and also to improve existing ones on RPV (bainitic steels). PERFORM 60 will be based on two technical sub-projects i) RPV and ii) Internals. The Users&apos; Group and Training sub-project shall allow representatives of constructors, utilities, research organizations... from Europe, USA and Japan to receive the information and training to get their own appraisal on limits and potentialities of the developed tools. An important effort will be made to teach young researchers in the field of materials&apos; degradation. PERFORM 60 will be run with 20 European organizations and Universities involved in the nuclear field.

Keywords: multi-scale modeling,rpv,internals,austenitivs stainless steels,bainitic steels,fracture toughness,irradiation assisted stress corrosion cracking