Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Integrated efficient, commercial viable, stand-alone and carbon neutral ammonia cracking solution, to unlock the global clean hydrogen supply chain (H2SITE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 48.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Hydrogen is essential for the net zero economy, particularly for hard-to-decarbonize industries, maritime sectors, and ammonia import hubs. However, its storage and transportation are challenging. Ammonia, a stable and carbon-free hydrogen carrier with a high hydrogen storage capacity, offers a solution. It can be liquefied at low pressure and high temperatures and is widely distributed globally via ships, trucks, or pipelines. The main issue with using ammonia as an energy carrier is the lack of cost-effective, carbon-neutral, commercial-scale technologies for ammonia cracking. Current methods are expensive, difficult to scale, and often rely on fossil fuels, increasing hydrogen supply costs by 110% to 330%. Notably, over 40% of transportation costs come from ammonia cracking, which requires significant energy and heat inputs, typically from inefficient combustion processes. At H2SITE, we are developing cutting-edge solutions for ammonia cracking. We are scaling up a standardized, modular, and commercially viable system that integrates a novel membrane reactor with a unique ammonia burner. This system aims to produce up to 200 tons of green hydrogen per day (tH2/d) with a projected Levelized Cost of Hydrogen (LCOH) of €4.7-6.6/kgH2 by 2028, depending on the application. We have successfully tested the membrane reactor and burner in relevant environments at a non-commercial scale. The ammonia burner is crucial for reducing LCOH, removing emissions and achieving lower operational costs. To commercialize the technology, we plan to scale up and integrate these components and demonstrate them at a commercial scale in the Port of Antwerp. We seek EIC support to complete the initial scale-up and demonstration and the equity phase to commercialize the technology. This will enable us to offer stand-alone solutions for port infrastructure, maritime transportation, industries, and import hubs, representing a €68 billion market opportunity.

Keywords: hydrogen,membrane reactor,decarbonisation,ammonia,process intensification
Pelvic floor dysfunction control device based on innovative soft robotic technology and digital interface (Yeda)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2450000.0
EU funding (EUR): 2450000.0
Participants: 1
Project status: SIGNED

Pelvic floor dysfunctions, including urinary incontinence and pelvic organ prolapse, affect over half of the female population, especially during pregnancy and menopause, leading to substantial financial costs and significant disruptions to daily life. Traditional pessary treatments are often uncomfortable, improperly fitted, and outdated, causing pain, slipping, and vaginal sores. Moreover, the rising incidence rates of pelvic floor dysfunction strain healthcare systems, with many women suffering in silence due to limited non-surgical alternatives and suboptimal results from existing treatments. There is a critical unmet need for an effective, comfortable, and user-friendly solution to manage pelvic floor dysfunctions, especially one that provides immediate relief and supports pelvic floor training. Yeda addresses this need with its advanced support device, which integrates patented soft robotic technology with an inflatable silicone form, offering both therapeutic benefits and immediate relief. Controlled by an electric pump and pressure sensors, the device provides real-time adjustments and customized support. The anterior end applies gentle pressure from the vaginal side, ensuring comfort and anatomical compatibility, while embedded sensors collect pelvic anatomy data for tailored support. The accompanying mobile application offers personalized pelvic floor muscle training programs and allows users to customize the device's size, optimizing comfort and effectiveness. Yeda's unique biofeedback mechanism, with deep vaginal placement, targets and engages deeper pelvic muscles, enhancing overall muscle engagement and effectiveness. This comprehensive solution not only supports pelvic organ function but also provides continuous monitoring, aiding healthcare professionals in treatment refinement and patient progress assessment.

Keywords: wellbeing,ehealth,urology and nephrology,medical devices,reproductive biology,pelvic floor dysfunction,urinary incontinence,pessary alternative,pelvic floor support,silicone device
Merging low-valent Bi redox catalysis with electrochemistry for the formation of C(sp3)-C bonds (Bi-echem)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-05-01
End date: 2026-04-30
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: SIGNED

The proposed work involves merging low-valent bismuth catalysis with electrochemistry to unlock eminently sustainable methods for C-C bond formation. The research outlined herein would constitute the first systematic foray into electrocatalytic organobismuth manifolds for the synthesis of organic molecules. Well-defined monomeric Bi(I) pincer complexes have recently been used to activate redox-active esters and alkyl halides via 1-electron and 2-electron pathways, respectively. In the first section, we propose a systematic electrochemical characterization of several N,C,N-Bi(III) pincer complexes, with particular emphasis on identifying the reversibility and potential of distinct redox states accessible by each complex. The cathodic reduction of Bi(III) species to their Bi(I) counterparts will also be performed in the presence of alkyl electrophiles to afford Bi(III)-alkyl species. The insights obtained from these foundational studies will be applied in the context of developing electrocatalytic manifolds for the C(sp3) carboxylation and C(sp3)-C(sp3) coupling reactions, two transformations that remain challenging even in the context of transition metal catalysis.

Keywords: bismuth,organic electrochemistry,small molecule activation
The evolutionary origins of human culture: a primatological perspective (CULT_ORIGINS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-07-01
End date: 2027-06-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Culture – the inheritance of behavioural phenotypes through social learning – is one of the most pervasive and influential characteristics of the human species. However, we lack knowledge about the origins of culture and to what extent its sub-components reflect species universals. Studying primates enables us to identify the evolutionary origins of human culture and the extent of its human uniqueness. Until now, it has largely been assumed that the social and cumulative components of human culture are derived phenomena that emerged after the phylogenetic split with the ape lineages. However, this claim may reflect a lack of adequate methodologies and research attention, leaving primate social culture underestimated. Now, combining novel techniques to investigate primate culture (deep learning) with innovative experiments in naturalistic settings, CULT_ORIGINS will overcome this issue by providing the first systematic study on social culture in primates. Rich datasets on macaques will be compared across an unprecedented number of groups to identify cultural variation in primate sociality and the existence of cooperative cultures. Great apes will be studied for their capacity to adopt cultural information flexibly and generate increasingly adaptive cultures – the pinnacles of human culture. Combining the strengths of experimental rigor and naturalistic observation in an unparalleled multi-group approach, CULT_ORIGINS will deliver step-change insights into the origins of human culture that go far beyond the State-of-the-Art. We will test the hypothesis that culture permeates the fabric of primates’ sociality, where it impacts the expression of cooperation, social learning and cumulative culture, like in humans. By synergizing approaches across biology, psychology, ethology and anthropology, CULT_ORIGINS will advance our understanding of the origins of culture, one of our most remarkable capacities, and challenge current perspectives about its human uniqueness.
Laser-assisted sYnthesis of Magnetically mOtile plasmonic chiral Nanocatalysts (LYMON)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy,Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 2
Project status: SIGNED

Catalysis holds immense significance in chemical manufacturing, being a key player in developing sustainable industrial processes with limited energy & resource consumption. In pharmaceutical industry, catalysis is crucial for enabling mass production of affordable life-saving drugs. However, developing efficient catalysts for this sector poses a formidable challenge due to the inherent asymmetry of many biological processes. This is particularly critical in producing anticancer drugs because their synthesis relies on intermediates or reactions whose asymmetric nature, known as chirality, withholds their massive production, limiting equal global access to best health treatments. An up-and-coming solution to address this dilemma is resorting to chiral plasmonic nanoparticles (NPs), as their outstanding optical rotation activity makes them well-suited for applications like polarization-sensitive photocatalysis, especially in the context of anticancer drug development. However, unleashing its full potential hinges on imbuing these chiral NPs with unusual properties like magnetism, allowing safe removal from products & recyclability without generating chemical waste. To date, creating a plasmonic structure that seamlessly integrates chirality with magnetic motility remains largely underexplored. The LYMON project addresses this conundrum by expanding the repertoire of chiral nanocatalyst construction methods through a groundbreaking laser-based pathway. This innovative approach, supported both experimentally & theoretically, promises to bring a new generation of highly specific magnetic chiroplasmonic nanocatalysts characterized by their ability to be reused multiple times. All of this permiting reducing wasteful side reactions & improving control over pharmaceutical production, especially for anticancer drugs. Moreover, it promises to expand the horizons of synthetic chemistry, paving the way for cutting-edge routes to produce highly efficient & selective molecules.

Keywords: laser synthesis,nanomaterials,eco friendly synthesis,catalysts development,enantioselectivity
The second life of modern period architecture: Resilient and adaptive renovation towards net-zero carbon heritage buildings (SINCERE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Efficient, sustainable and inclusive energy use
Action type: Research and Innovation actions
Partnership: B4P (co-programmed)
Countries involved: Greece,Israel,Italy,Spain,Germany,Sweden,Czechia,Malta,Switzerland,United Kingdom
Call: Sustainable and resource-efficient solutions for an open, accessible, inclusive, resilient and low-emission cultural heritage: prevention, monitoring, management, maintenance, and renovation (Built4People) (HORIZON-CL5-2022-D4-02, 2022)
Start date: 2023-10-01
End date: 2026-09-30
Duration (months): 36.0
Total project cost (EUR): 4355400.0
EU funding (EUR): 4355400.0
Participants: 18
Project status: SIGNED

Today, 19th and 20th c. modern period buildings are the trademark of numerous European cities, forming a great part of EU Built Heritage, reflecting and shaping the identity of our local, national and multinational societies. Considering that historic buildings are ineffective in terms of energy consumption for heating and cooling, among the biggest restoration and renovation challenges is to enhance the energy performance of historic buildings. SINCERE aims to elucidate the values of Built Heritage and provide the tools for optimizing the carbon footprint and energy performance of historic buildings, towards the requirements of net-zero-carbon-buildings, by utilizing innovative, sustainable, and cost-effective restoration materials and practices, energy harvesting technologies, ICT tools and socially innovative approaches. SINCERE adapts a multi-scale concept, from material-, to building-, to neighbourhood- to city-scale, applied on the three main parts of buildings: structure, external envelope (opaque), and transparent parts, implemented at different time-frames, in order to provide decision making tools to the stakeholders involved in the process, considering the full-service life of the buildings, including restoration, operation, monitoring and maintenance phases. Energy performance in terms of retrofitting materials and solutions will be optimized according to the buildings’ unique structural, architectural, functional and materials characteristics, their environmental setup, as well as local future climate change scenarios. SINCERE will provide a palette portfolio of sustainable restoration options that will be evaluated by H-BIM/H-DT tools in order to enable the selection of optimum solutions and the planning of necessary adaptation actions. SINCERE will also focus on raising awareness and empowering Europeans to promote the concept of preservation CH buildings by disseminating the obtained results through national and international scale activities.

Keywords: hbim digital twin,low carbon restoration mortars,self healing,radiative cooling,bipvs,thermal insulation,lca lcc,climate change scenarios,social awareness,architectural values
Psychosis risk subtypes and white matter integrity: exploring subgroup trajectories (RISK-MATTER)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,United States
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-07-01
End date: 2026-12-31
Duration (months): 30.0
Total project cost (EUR): 220966.8
EU funding (EUR): 220966.8
Participants: 2
Project status: SIGNED

Psychotic disorders rank among the top 25 global causes of disability, impacting individuals, their families, and society. Much of this burden stems from early onset and poor clinical outcomes. While approximately 30% of individuals experience persistent symptoms, illness trajectories following a first psychotic episode vary widely and remain poorly understood. Cumulative genetic and environmental risk exposures and underlying white matter (WM) microstructure abnormalities have been associated with clinical outcomes during the first few years following psychosis onset. Still, it remains unexplored how different combinations of risk exposures are linked via WM microstructure with short- and long-term psychosis outcomes. Thus, RISK-MATTER aims to identify biologically and clinically meaningful subgroups of individuals with recent-onset psychosis based on their different genetic and environmental risk profiles by employing advanced clustering approaches. I will assess whether stratifying participants into these more similar subgroups enhances the effectiveness of supervised machine learning models that utilize WM microstructure and baseline clinical features to predict traditional one-year clinical outcomes. Yet, traditional retrospective assessments to evaluate clinical outcomes are prone to memory and assessor bias. Hence, I will further re-contact a subset of individuals up to eight years after psychosis onset to collect traditional and smartphone-based assessments to determine whether my models’ predictive accuracy is robust when evaluating longer-term and real-life outcomes. During this project, I will build expertise in diffusion-weighted imaging, unsupervised machine learning, and smartphone-based assessments, mentored by Prof. Pasternak (Harvard Medical School) and Prof. Koutsouleris (Ludwig-Maximilian-University). These skills will bolster my academic profile as a neuroscientific psychologist and facilitate my growth as an independent research group leader.

Keywords: recent onset psychosis environmental risk factors,genetic risk,white matter integrity,machine learning,clustering,smart phone based assessment
Career Accelerator for Research Infrastructure Scientists 2nd generation (ARISE2)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Germany,France,Austria,Sweden,Belgium,Spain,Netherlands,Czechia,Denmark
Call: MSCA COFUND 2023 (HORIZON-MSCA-2023-COFUND-01, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 7164000.0
EU funding (EUR): 7164000.0
Participants: 18
Project status: SIGNED

The ARISE2 program will train 50 postdoctoral fellows for roles as research infrastructure (RI) scientists—highly skilled and much-needed scientific experts responsible for developing, providing, and managing scientific services in the life sciences. Europe has made significant investments in RI development, necessitating dedicated programs that will produce qualified experts to drive these advancements. Building upon the success of the MCSA-supported ARISE program, ARISE2 continues its mission to train researchers for RI roles. Selected fellows will develop novel technologies and methods that enable faster, more precise analyses across multiple life sciences fields, accelerating our understanding of life from ‘molecules to ecosystems’. As life sciences RIs are generating large volumes of data, we are introducing data science and AI as a new focus in ARISE2. Fellows will be challenged to simplify, and ideally automate, FAIR data management for the benefit of users, ultimately leading to greater FAIRification and improved data integration for European researchers. They will be supported by their supervisors and advisors from EMBL and 17 ARISE2-associated partners (9 non-academic), who engage in collaborative projects, hosting inter-sectoral and inter-disciplinary secondments or participating as trainers, thereby increasing competencies, infrastructure, supervision and exchange. The implementing partner will lead ARISE2 training and the development of further partnerships. In addition to training through research, fellows will benefit from a unique training portfolio to acquire RI professional competencies, including data science and AI, scientific and transferable skills and opportunities to foster professional networks. ARISE2 will generate open and micro-credential-ready training materials, facilitating the expansion of similar RI training programme across Europe and standardising this new career path in research.

Keywords: life science,technology and method development,research infrastructures,data science,postdoc
2D Material-based Non Volatile-PHotOnic Synapsis for ultra-low Energy Neural networks (2D PHrOSEN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-02-01
End date: 2026-01-31
Duration (months): 24.0
Total project cost (EUR): 203464.32
EU funding (EUR): 203464.32
Participants: 1
Project status: CLOSED

Neuromorphic computing is expected to have a transformative impact by exploiting the brain like computations. During the last two decades, Neuromorphic computing has been implemented on electronics, with the most important circuit element capable of best mimicking neurons and synapses that is the memristor. Yet, constructing a highly interconnected networks of memristors to resemble biological architecture requires metal wires with extremely scaled area that results in an immense heat generation and power consumption, hindering the neuromorphic electronics development. Recently the new field of neuromorphic photonics has attracted a lot of interest as a valid alternative. In neuromorphic photonics the network connections are made of optical waveguide that provides inherent parallelism, ultra low latency, and almost zero power dissipation. However neuromorphic photonic will only meet its expectation as a groundbreaking technology when an Ideal photonic memristor is available. The ideal photonic memristor (currently missing) should adjust the amplitude of transmitted light in a non-volatile and analog manner, not via light absorption but through light phase change, to minimize the synapsis insertion losses. In this project I will demonstrate the low loss photonic memristor by innovative exploitation of energy band alignment and refractive index modulation of 2-Dimensional (2D) material heterostructures. I will embed the 2D heterostructure within a photonic integrated Mach- Zehnder Interferometer to showcase the non-volatile optical phase shifting with 1-10 fJ energy consumption per bit. This project will conduct interdisciplinary research across light-matter interaction, that requires contributions from materials science, physics, photonics and electronics. Positive outcome of this action will lead to a breakthrough in the development of neuromorphic photonics, thus a revolution in various aspects of smart human societies that rely on high throughput data computation.

Keywords: neuromorphic photonics,2 dimensional materials,photonic memristors,photonic integrated circuits,transition metal dichalcogenides,