Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
AI Team Coaching for Distributed Teams Across Globe (theCoRD.ai)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Romania
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

theCoRD is an AI team coach designed to enhance performance by observing and analyzing interactions, engagement, meeting facilitation, conflict resolution, alignment, and decision-making. It evaluates four key managerial skills: alignment, informational, relational, and delegation, providing targeted recommendations. Integrated with Teams, Zoom, and Meet, theCoRD observes aspects like collaboration, engagement, facilitation, consensus building, goal setting, decision velocity, timing adherence, and managerial skills. After analyzing 4-6 meetings, it delivers actionable insights and specific improvement recommendations, sending suggestions before and after meetings to enhance results. Progress tracking monitors development across metrics, ensuring measurable improvements. Benefits include 30% shorter meetings, a 40% increase in decisions made, a 20% rise in revenue per employee, and a 40% reduction in unproductive meeting costs. TheCoRD's breakthrough innovation lies in its novel technology and approach, utilizing a proprietary deep learning algorithm to analyze team dynamics in real-time during live interactions. This real-time, actionable feedback mechanism is unprecedented in team coaching tools and sets theCoRD apart in the market. By pioneering a new segment within the team coaching market focused on real-time AI-driven coaching, theCoRD aims to establish new standards and practices in industries that rely heavily on team collaboration and remote work. This transformative approach to team coaching integrates AI into the core of team interaction analysis, potentially rendering traditional coaching models obsolete and revolutionizing the landscape of team coaching.

Keywords: ai team coaching,artificial intelligence,team dynamics,organisational development,productivity,employee engagement
Helical Out-of-Equilibrium Systems: Exploring Light-Induced Structural Distortions (HeliOS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Helical architectures are prevalent in natural and artificial settings due to their mechanical robustness, chiroptical properties, and ability to assemble compactly through intra- and intermolecular interactions. We propose that reversible distortions to these structures can unlock new behaviors. Inspired by recent advancements in supramolecular chemistry and light-responsive molecules, we aim to couple light-responsive units (LRUs) to helical structures to drive them out-of-equilibrium (OOE), thereby modulating their functionality and achieving photoactuation. Adopting organic and metal-organic spring-like model systems, we aim to achieve compression, extension, and complete unwinding of the helices under photoirradiation. In the OOE state, we hypothesize that the systems can store and release energy, making them promising candidates for optomechanical work and offering an alternative design strategy for molecular solar-thermal (MOST) materials. Furthermore, our approach enables the precise placement of LRUs within the helical structure, which is anticipated to provide customized optomechanical responses, such as bending and twisting, and allow new light-gated reactivity and feedback loops. Expanding this concept, we will explore larger, polymeric versions of these materials in bulk, such as films and fibers, to achieve light-powered translation, rotation, and lifting of objects. This fundamental study establishes a new research area focused on using LRUs to perturb discrete helical structures OOE, advancing the current approaches to perform mechanical work on the macroscopic level and presenting a novel design approach for MOST materials. Success will undoubtedly catalyze interest in exploring other helical architectures beyond the model systems studied here, achieving photoactuators of greater complexity in their operation and function.

Keywords: photoswitches,dynamic covalent,supramolecular,self assembly,helical materials,systems chemistry,most,photoactuators
Single Cell PTSD: Novel Target Identification (sc-PTSD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Poland
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-04-01
End date: 2031-03-31
Duration (months): 60.0
Total project cost (EUR): 1403931.0
EU funding (EUR): 1403931.0
Participants: 1
Project status: SIGNED

Post-traumatic stress disorder (PTSD) is a devastating psychiatric disease triggered by severe psychological trauma, affecting 4% of the global population - a prevalence projected to rise due to ongoing conflicts like the war in Ukraine and the looming threat of climate change. Despite its widespread impact, we lack effective treatments of PTSD, placing a significant burden on individuals and society. Previous PTSD research was hindered by limitations such as bulk tissue analyses, a lack of epigenetic focus, or small sample sizes. These drawbacks limit our understanding of cell-type-specific alterations during PTSD. My proposed project will leverage single-nuclei RNA sequencing, DNA methylation profiling, and 3D chromatin structure analysis to achieve unprecedented insights into PTSD pathology. Specifically, I aim to: 1) Identify cellular, epigenetic, and transcriptional perturbations in a post-mortem human brain PTSD cohort, revealing promising molecular targets. 2) Characterize classical models of PTSD using single-nuclei genomics, and develop novel humanized model of PTSD. This will enable the identification of the most relevant model for human PTSD, and streamline further validation of targets. 3) Test the efficacy of novel as well as already identified targets from my pilot animal study by utilizing epigenome-modifying tools to alleviate PTSD pathology in mouse models. This project will deepen our understanding of PTSD at unprecedented resolution, ultimately validating novel molecular targets and paving the way for more effective interventions in future.

Keywords: stress related disorders,single nuclei genomics
Advancing Amino Acid Electrosynthesis through Integrated Active Site Design, Mechanistic Understanding, Free-Standing Electrode Fabrication, and Continuous Flow Cell Engineering (eSyn-Amino acid)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-08-01
End date: 2027-07-31
Duration (months): 24.0
Total project cost (EUR): 263393.28
EU funding (EUR): 263393.28
Participants: 1
Project status: SIGNED

Amino acids (AAs) are essential raw materials in the food and pharmaceutical industries. The global AA market was valued at around USD 28 billion in 2023, and is expected to reach around USD 63 billion by 2033. Traditional microbial and chemical processes involve lengthy reaction times, toxic reagents, and large centralized factories. In the context of carbon neutrality, electrosynthesis of AAs with small-scale devices is an ideal alternative to address these issues. However, current AAs electrosynthesis suffers from significant challenges: (1) A lack of comprehensive mechanistic understanding of the active sites-intermediates/target products correlation, leading to an insufficient theoretical foundation for catalyst design. (2) The absence of engineering-focused studies on optimizing efficient flow reaction cells and large-size cathodes limits the practical application at higher current densities. This project aims to address these challenges through three key approaches: catalyst design, size effect-related mechanistic studies, and engineering of large-scale carbon cathodes and flow cells. Specifically: (1) Synthesize bimetallic active centers (Fe-Ni, Fe-Cu, Ru-Ni, Ru-Cu) with varying sizes, from single atoms to diatoms, clusters, and nanoparticles, for AA electrosynthesis. (2) Conduct mechanistic studies using in situ XAS and FT-IR to identify the true active sites and obtain reaction intermediates, to enhance understanding of reaction mechanisms and the important C-N coupling process, and further establish the intrinsic relationship between active sites, intermediate selectivity, and catalytic activity. (3) Develop large-size carbon electrodes via a self-assembly hydrogel strategy and a flow electrochemical cell system for continuous AA synthesis. This project will greatly expand the understanding of the structure-activity relationship, and guide the development of highly efficient AA electrosynthesis systems on a practical scale.

Keywords: electrosynthesis of amino acids,single dual atom catalysts,in situ xas,large size carbon electrodes,flow electrochemical cell
Guiding electron transfer at the microbe-electrode interface: the role of MtrCAB (MTRoute)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal,United States
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-04, 2022)
Start date: 2023-06-01
End date: 2025-05-31
Duration (months): 24.0
Total project cost (EUR): 172618.56
EU funding (EUR): 172618.56
Participants: 2
Project status: SIGNED

Rising population and living standards have caused pollution, water scarcity, and resource shortages. To mitigate these issues and adopt sustainable development methods, we need innovative environmental technology. Bioelectrochemical systems (BES) are a rapidly growing and versatile technology that exploits the ability of electroactive microbes to conduct electron transfer between electrodes to oxidise or reduce substrates, such as organics present in wastewater, opening up a wide range of applications for wastewater treatment, nutrient recovery, and bioenergy production. The rate at which electron transfer occurs is the key process behind the development of BES and is one of the defining factors of the implementation of BES on a large scale. Recent research has revealed that the porin-cytochrome complex MtrCAB, which is responsible for electron transport across the outer membrane, is found in a wide variety of microbes, including several electroactive bacteria that participate in BES, demonstrating the potential significance of MtrCAB for extracellular electron transfer. MTRoute is aimed to provide information on the performance of MtrCAB from diverse bacteria in electron transfer, as well as identify the molecular mechanisms and factors that can enhance electron transfer rates. Synthetic biology tools will be used to incorporate these insights to the extensively studied electroactive microbe Shewanella oneidensis MR-1 to push forward the practical implementation of BES. Towards this aim, MTRoute will rely on a multidisciplinary research project that will based on the ER's expertise in bioreactor application, the host team expertise on evaluating electron transfer processes of multiheme cytochromes, and on the secondments' supervisor expertise in genetically modify electroactive microbes. The success of MTRoute will contribute to tackle several UN sustainable goals and build a bio-based economy, one of the strategic priorities set by the new Europe 2030 program.

Keywords: extracellular electron transfer bioelectrochemical systems electroactive organisms genetic engineering multiheme cytochromes
Intelligent BIo-inspired flapping-wing aerial Robots for noise and air quality Data Sampling in environment conservation (I-BIRDS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2025-POC, 2025)
Start date: 2025-10-01
End date: 2027-03-31
Duration (months): 18.0
Total project cost (EUR): 214285.71
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

I-BIRDS proposes the development of the first intelligent system capable of generating high-resolution 3D maps of noise and air quality in urban and industrial environments using bio-inspired flapping-wing robots. This system will significantly reduce the cost of manual sampling for noise and pollutant levels, as well as the deployment and maintenance of static sensor networks. Flapping-wing Unmanned Aerial Vehicles (UAVs), also known as ornithopters, offer key advantages over conventional propeller-driven drones. They are quieter, safer, and better suited for operations in populated areas. In particular, the use of traditional UAVs is not suitable for noise sampling due to the internal noise generated by the propellers. I -BIRDS builds on the expertise of the Principal Investigator, who successfully developed ornithopters with an unparalleled level of autonomy, capable of stable and precise flight without human intervention. He also validated models and demonstrated that the combination of flapping and gliding is significantly more efficient than conventional UAV propulsion systems. With the new system, environmental sampling can be carried out with higher spatial resolution than static methods, at a lower cost—especially across large areas—and with minimal noise and enhanced safety, due to the absence of propellers and the use of low-weight, soft materials. I-BIRDS aims to increase the Technology Readiness Level (TRL) of previous autonomous flapping-wing prototypes, delivering an innovative and disruptive solution for environmental monitoring. The objective is to integrate and test a fully functional system, obtain operational flight authorisation, and bring a viable product to market within a few months after the project concludes.

Keywords: aerial robotics,unmanned arial systems,bio inspired systems,enviroment conservation,noise monitoring,air quality monitoring
3D Printed Micro-Optics to the Market (3DPRINTOPTIXMARKET)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany,Austria
Call: EIC Transition Open 2022 (HORIZON-EIC-2022-TRANSITION-01, 2022)
Start date: 2023-06-01
End date: 2026-05-31
Duration (months): 36.0
Total project cost (EUR): 2496962.5
EU funding (EUR): 2496602.75
Participants: 2
Project status: SIGNED

In the project 3DPrintoptixMarket, we are going to take 3D printed micro-optics to the market. The technology had been developed in the framework of PoC grant 3DPRINTEDOPTICS by the group of Harald Giessen, who had published key papers of this technology and who founded the company Printoptix GmbH as an outcome. We are going to build complex 3D printed multiplet micro-lenses for augmented, virtual and mixed reality (AR/VR/MR) applications and will address a market that is growing at more than 40% annual rate to reach a market size of over 300 billion USD in the year 2028. For this purpose, we are going to team up the Printoptix company with one of the leading eye tracking companies, Viewpointsystem GmbH from Vienna, to develop a first industrially viable demonstrator that integrates 3D printed micro-optics into their AR/VR goggles to read out the eye pupil position upon infrared illumination. We are going to take this technology demonstrators to early customers, which use such systems for remote repair, remote advice, and for customer training and monitoring. Upon success, our technology will be taken to larger customers that address the giant AR/VR/MR market, which includes teleconferencing, remote medicine, servicing and training, and gaming. Simultaneously, we are going to explore viable business models for 3D printed micro-optics and address key business numbers such as manufacturing cost per part, overhead, investments etc. One key part of our proposal is to lower the cost per part to reach numbers below existing technologies. Furthermore, we are going to prepare a business plan to get 3D printed micro-optics investor-ready. This will assure that our worldleading, disruptive 3D printed micro-optics technology ansatz provides unique high-tech solutions for global markets, which are right now not addressed by Asian or American companies. This will therefore be a hallmark example for “Made in Europe” high technology.

Keywords: 3d printed camera lenses,eye tracking,freeform optical systems,complex micro optics
LINKING SOIL BIODIVERSITY AND ECOSYSTEM FUNCTIONS AND SERVICES IN DIFFERENT LAND USES: FROM THE IDENTIFICATION OF DRIVERS, PRESSURES AND CLIMATE CHANGE RESILIENCE TO THEIR ECONOMIC VALUATION (BIOservicES)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Soil health and food
Destination: Soil health and food
Action type: Research and Innovation actions
Countries involved: Spain,France,Belgium,Germany,Italy,Netherlands,Latvia,Romania,Switzerland,United States,United Kingdom
Call: Soil biodiversity and its contribution to ecosystem services (HORIZON-MISS-2022-SOIL-01, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 7398540.0
EU funding (EUR): 7398540.0
Participants: 22
Project status: SIGNED

The main objective of BIOservicES is to understand the interconnection between soil organisms (virus, bacteria, archaea, fungi, protists, nematodes, microarthropods, earthworms, isopods, millipedes, insects and spiders) and the delivery of multiple soil ecosystem functions and services at different scales (field vs landscape), identifying the pressures and drivers resulting from different land uses and climate change, and performing an economic valuation of the contribution of soil organisms to ecosystem services. BIOservicES will also deepen in the relationship between soil organisms and soil structure, and how this interaction is affected by land use and management intensity, to contribute to the Soil Mission objective 6 “Improve soil structure to enhance habitat quality for soil biota and crops”. BIOservisES will thus deliver new knowledge, new indicators based on soil organisms and the ecosystem functions and services in which they are involved and digital decision-support tools and models to help design climate resilient management practices and monitoring/conservation/restoration programmes adapted to a range of environments (land uses and biogeographic regions) across Europe, to maintain and foster the multiple soil ecosystem functions and services in which soil organisms are involved. It will also give relevance to soil health and soil ecosystem functions and services delivered by soil organisms in the update of EU and National legislations. For this, BIOservicES is using experimental sites across 8 land uses and 5 biogeographic regions from Europe, as central hubs for co-creation and co-design (multi-actor approach, responsible research and innovation (RRI) and open science)

Keywords: land uses,pressures,climate change adaptation,soil functions,economic valuation,incentives,stakeholders engagement
Personalised Medicine by using an Advanced Point-of-Care Tool for Stratified Treatment in High Risk Cardiovascular Patients (PoCCardio) (PoCCardio)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Unlocking the full potential of new tools, technologies and digital solutions for a healthy society
Action type: Research and Innovation actions
Countries involved: Austria,Belgium,Spain,Germany,Denmark,United Kingdom,Iran, Islamic Republic of,Cyprus
Call: Optimising effectiveness in patients of existing prescription drugs for major diseases (except cancer) with the use of biomarkers (HORIZON-HLTH-2022-TOOL-11, 2022)
Start date: 2023-12-01
End date: 2028-11-30
Duration (months): 60.0
Total project cost (EUR): 14023432.5
EU funding (EUR): 13978057.0
Participants: 8
Project status: SIGNED

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Besides established risk factors such as elevated blood pressure, blood glucose or lipid levels, circulating proteomic as well as genetic markers allow further stratification of patients. While some of these markers can be measured routinely in low-threshold healthcare institutions, others require access to highly specialized and costly laboratory environment which usually can be found only within larger tertiary settings. The aim of this project is to advance and tailor a point-of-care (PoC) tool, which was recently developed within the framework of HORIZON 2020. Using cutting-edge lab-on-a-chip (LoC) and microfluidic technology, the tool will be further developed to measure qualified biomarkers and polymorphisms from finger prick blood, in order to help identify, classify and monitor cardiovascular patients at high risk. The clinical validation of these biomarkers and the PoC tool will then be performed in a prospective, randomised multinational trial which will include only existing and approved pharmaceuticals. Based on their specific pattern of qualified biomarkers, patients will be assigned either to standard pharmacological treatment, or tailored intensified treatment. Data derived from the clinical validation study will constitute a rich source for complex AI-powered computational analysis to explore potential predictors for primary and secondary outcome parameters. The trial will further provide the scientific foundation to support regulatory authorities in regard to approval of companion diagnostics, and recommendations for the prescription of drugs, respectively. Overall, this project aims to improve care and treatment efficacy in CVD patients through an advanced biomarker-driven PoC-based personalised medicine. To achieve these aims, a well-balanced consortium of six academic research partners and two SMEs has been brought together.

Keywords: cardiovascular disease,biomarker,genomic marker,point of care tool,personalised medicine,ai