Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Enantioselective Light-induced Catalysis for Organic Synthesis (ELICOS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2016-01-01
End date: 2020-12-31
Duration (months): 60.0
Total project cost (EUR): 2357901.0
EU funding (EUR): 2357901.0
Participants: 1
Project status: CLOSED

Photochemical reactions are induced by ultraviolet or visible light and they enable the construction of molecular skeletons that are difficult or even impossible to access by any other means. In order to secure a widespread application of these reactions in organic synthesis and in order to make the respective products available for high-tech applications, it is required that photochemical reactions can be performed enantioselectively, i.e. that the three-dimensional architecture of the product molecules is unambiguously defined. Despite some progress in recent years, this challenge has as yet remained unsolved. It is the objective of this proposal to develop catalytic methods that allow the enantioselective synthesis of a broad variety of compound classes by light-induced reactions. The mode of action of potential catalysts is based on energy transfer or on wavelength-selective excitation. In the former scenario, the substrate-catalyst complex will be held together by non-covalent interactions, which position the substrate for an efficient energy transfer and for an enantioselective approach of the reagent. In the latter approach, acid-base interactions in the substrate-catalyst complex will lead to a significant bathochromic absorption shift of the substrate, enabling a selective excitation within the complex and a subsequent enantioselective reaction pathway within a spatially defined chiral environment. Both approaches include the option to employ sunlight as the exclusive energy source to drive enantioselective processes without the need to apply external heat or pressure.
High Efficiency Distributed Power Plant (HighPower)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Finland
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2014, 2014)
Start date: 2015-02-01
End date: 2015-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The EU is committed to lower its C02 emissions 80-95% by 2050. Current energy technologies do not enable to reach this goal. Today, in conventional power generation, electrical efficiency is around 15-45%. Convion will commercialize a small power plant for distributed power generation that reaches electrical-efficiency up to 70% (and above 90% in CHP mode). Convion´s power plant is based on Solid Oxide Fuel Cells (SOFC) technology that converts hydrocarbon and hydrogen fuels like biogas, natural gas, and hydrogen to heat and power without harmful emissions. Convion´s SOFC power plant enables to reduce greenhouse gases by more than 40-60% compared to conventional combustion process. In addition Convion´s innovation increases energy security for many EU regions and improves power stability for end-users like hospitals, data centres, production units and households. Convion is an established company at fuel cells market that combines more than 250 cumulative years of experience in SOFC systems development. Convion is dedicated to develop a state of the art exceeding SOFC stationary application in 50-300kW power range. Demand for high-efficiency power solutions is on the rise and fuel cells technology is seen as the backbone of the energy industry in the next decades. Market opportunity in Convion´s segment is estimated to reach over 1B € by 2020. H2020 SME-instrument is seen as a perfect match for Convion´s project objectives that could support the last product development phase and enable successful market introduction of the Convion SOFC power plant. In Phase-1 Convion will further develop company´s business model, customer strategy and marketing plan to take advantage of Convion´s strong position at distributed power generation market and achieve successful product commercialisation. Manufacturability study in Phase-1 is expected to lower the technology costs and make preparations for mass production.

Keywords: solid oxide fuel cell,fuel cells,sofc system,sofc power plant,distributed power generation,stationary power plant,small power plant,low carbon electricity production
Development of a reliable quality control system using advanced Non-Destructive Evaluation (NDE) technologies for the production environment of leak-free fuel tanks from plastics and composites (LeakFree)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Türkiye
Call: Small business innovation research for Transport (H2020-SMEINST-2-2014, 2014)
Start date: 2015-06-01
End date: 2017-03-31
Duration (months): 22.0
Total project cost (EUR): 1196286.75
EU funding (EUR): 837400.73
Participants: 1
Project status: CLOSED

Nowadays, the usage of Plastic Fuel Tanks (PFTs) has dominated over steel tanks as they offer numerous advantages such as lower weight, higher corrosion resistance, better crash performance and lower total systems costs. Tank manufacturing from plastics and composites in automotive sector is increasingly adapted to mass productions to meet the ever growing demand. The management of quality control (QC) systems for factory environment poses challenges in the absence of relevant experience in the development and use of in-situ non-destructive evaluation (NDE) technologies. The problem currently faced by the automotive industry is that most techniques that fall within the accepted leak detection sensitivity requirements are based on manual intensive and operator-dependent tasks. Leak detection techniques with higher sensitivity do exist; however they are characterized by high investment and operational costs. Hence, their implementation is not economically feasible as the related costs outweigh their benefits for the automotive QC purposes. The LeakFree project targets at bringing to the market a low cost leak detection system that is fast, accurate, traceable and automated for mass production environments in the fuel tanks production industry. The system eliminates the disadvantages associated with the manual-intensive and operator-dependent techniques, currently employed by the industry, through the development of an inspection technique based on Acoustic Emission (AE). The LeakFree acoustic technology has already been demonstrated in fuel-tank production environment and the project targets at bringing the system to the market. The activities to be performed span from design and prototyping to validation, demonstration, performance verification and standards certification. Additionally, efforts will be placed at connecting the LeakFree product to the Enterprise Resource Planning (ERP) system of the rotomolding production company.

Keywords: plastic fuel tanks,acoustic emission,acoustic leak detection,rotomolding production,quality control system,non destructive evaluation technology,enterprise resource planning integration
Development of an innovative Mini Helicon Thruster (MHT) thruster suitable for small satellites (MHT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: SME instrument
Countries involved: Italy
Call: Engaging SMEs in space research and development (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-08-01
End date: 2018-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

This work presents a phase 1 proposal on the development of an innovative propulsion system specifically studied and developed for mini and micro platform. The mini helicon thruster proposed is the outcome of more than ten years of a research started at University of Padua and continued within Technology for propulsion and innovation. The technology has been proven on a relevant environment with thrust measurements showing performances within the target range of mini and micro platforms. After a wide overview of competitors and market perspective it has been realized that this technology may have a disruptive impact on the future space market of small satellites. In this proposal a refinement of the business plan is proposed through the following key activities: better identification of market requirements by detailed contact with potential customer, deeper evaluation of competitors’ strength cross checking their performances with customer needs, identification of supply chain, definition of development plan, suppliers, industrialization plan, risk assessment and contingency plan, development of market plan and IP protection strategy.

Keywords: plasma thruster,micro satellites,mini satellites
Transferring autonomous and non autonomous cell degeneration 3D models between EU and USA for development of effective therapies for neurodegenerative diseases (ND) (CROSS-NEUROD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Italy,Greece,United States
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2017, 2017)
Start date: 2018-06-01
End date: 2024-03-31
Duration (months): 70.0
Total project cost (EUR): 693000.0
EU funding (EUR): 594000.0
Participants: 4
Project status: SIGNED

Neurodegenerative diseases (NDs), such as Dementia, Parkinson’s and motor neuron diseases, are a major and continuously growing worldwide health issue, particularly devastating for patients and their families. Yet, no cures are available, largely due to the lack of knowledge of ND pathogenic mechanisms. Strikingly, co-occurrence of several NDs in the same patient or family, and evidence that mutations in the same gene lead to several NDs are indicating that common molecular pathways are involved across NDs. Elucidating these shared mechanisms could have a major impact for the treatment and the prevention of this spectrum of NDs. Leveraging on our expertise in studying autonomous and non-autonomous mechanisms of NDs, we propose an innovative, multinational and multidisciplinary collaborative research project to perform network analyses across NDs and identify key common underlying mechanisms. The CROSS-NEUROD project is focused on: 1) the development of integrative in vitro 3D disease models (mini-brains, mini-spinal cords, and motor unit) to elucidate common cellular and molecular pathways across NDs; 2) the validation in animal models of the therapeutic targets identified. To achieve these aims we will consolidate research partnerships through staff exchanges and networking activities between 3 European research organizations, two of which from Italy, one from Greece, and a partner, USA. The project is based on a 4 years coordinated joint program of exchanges of researchers for short periods. It has been developed from active bilateral cooperation between individual countries and partners and represents the natural progression of our previously funded and successfully completed EU 7PQ IRSES grant “No-MND” (2013 call). Our ongoing research programs are well supported by funding. The RISE scheme provides a unique opportunity to integrate ongoing collaboration activities into a coherent program addressing an issue of high priority for public health both in EU and USA.

Keywords: neurodegenerative diseases,motor neuron diseases,parkinson disease,frontotemporal dementia,induced pluripotent stem,organoid,cells,amyotrophic lateral sclerosis,spinal muscular atrophy,therap
Innovation Denmark 2015-2016 (INNO DK)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Denmark,Denmark,Denmark,Denmark,Denmark,Denmark
Call: Enhancing the innovation management capacity of SMEs (H2020-Adhoc-2014-20, 2014)
Start date: 2015-01-01
End date: 2016-12-31
Duration (months): 24.0
Total project cost (EUR): 260307.5
EU funding (EUR): 260307.5
Participants: 8
Project status: CLOSED

The Danish EEN will provide skilled personnel to provide two services: Key Account Management Services to SMEs in the SME Instrument and Enhancing Innovation Management Capacity building services to potential high growth SMEs. A total of minimum 80 service packages will be implemented. Two tools will be used to carry out these tasks - Growth Wheel for the KAM role, to provide a brief and simple feedback on the company's management ability and IMP3rove for all EIMC cases, to provide a thorough picture of the innovation management capacity of the SMEs. Companies in the EIMC work will be integrated with the wider Danish and European innovation support eco-system.

Keywords: innovation management capacity building,sme instrument,key account management,imp3rove
The Professional Development Network for the Next Generation (Goodwall)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Students aged 19-24 normally are in the mid to late years of college. They start to worry about career development and may look for summer internships and other real-world experience to prepare themselves for life after graduation. No social network is designed to help this large group of people to share and communicate the ideas and struggles they face when accommodating the drastic changes happening in their lives. LinkedIn targets adults over 30 years and has failed to grasp this demographic. Enter Goodwall, the platform was launched as a pilot in 2015 targeting 14-18-year olds and has been a remarkable success. If we want to successfully expand to the 19-24 demographic, a major revamp of functionalities and stakeholders needs to take place. Goodwall plans to unite three verticals, social networks, university recruitment, and employee recruitment who share the same demographic but offer separate services. Therefore, the main users will be Students low experienced job seekers, and universities and companies looking for high talented students and graduates. We have the firm target of 7,500 Universities/Companies partners after 5 years of the upgraded social network in the market. Monetisation is proven as we generate over €600,000 yearly with the pilot platform as it stands over >1M users and over 100 university partners. However, we are not yet a profitable company and require aggressive financing to meet growth forecasts in the short to medium term.

Keywords: social network,excellence in education,job creation,network effect,social inclusion
Biogeography and natural hybridization in the genus Mentha (GENOMINT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

Understanding the biogeographic histories of organisms is at the heart of evolutionary, ecological, and conservation research. In plants intraspecific hybridization is a common evolutionary event and a major method for speciation. Hybridization has the ability to create novel large scale genomic combinations. In addition, fertile hybrids with the ability to backcross to its parents can act as genomic highways, mediating gene flow between parental species. Hybridization is therefore a major source of genomic variation and it can act as a mode for unconventional interspecific genetic transmission. However, there is a large knowledge gap in the understanding of the evolutionary and ecological roles hybridization plays and how it affects the biogeographic history and genomic diversity of plants. In this project I will investigate these questions in the plant genus Mentha, which contains many natural intraspecific hybrid species. I will infer the effect of hybridization on dispersal rates and biogeographic history using whole chloroplast genomes from samples obtained from historical collections. Furthermore, I will investigate the effect hybridization have on the genomic diversity within Mentha and how hybridization have shaped the genus’ evolutionary history. Finally I will establish whether Mentha hybrid species act as genomic highways facilitating gene flow between parental species. The results of this fellowship will significantly increase our knowledge of the evolutionary importance of hybridization and its importance for shaping biogeographical patterns and genomic diversities in plants.

Keywords: hybridization,polyploidization
Integrated nanoparticle isolation and detection system for complete on-chip analysis of exosomes (INDEX)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Estonia,Italy,France,France,United States,Denmark
Call: FET-Open research and innovation actions (H2020-FETOPEN-1-2016-2017, 2017)
Start date: 2017-10-01
End date: 2021-03-31
Duration (months): 42.0
Total project cost (EUR): 2983525.0
EU funding (EUR): 2982275.0
Participants: 7
Project status: CLOSED

The aim of Project INDEX is to isolate and characterize nanoparticles available in bodily fluids through development and integration of novel technological breakthroughs. The technology will enable the analysis of clinically valuable nanoparticles called exosomes towards new generation diagnostics. Exosomes are known to mediate communication between cells and their effective utilization holds a great promise of revolutionizing the standard of clinical care. However, their detection and molecular profiling is technically challenging. The proposed technology will isolate exosomes that are as small as 30nm in diameter from human plasma with high purity, and provide in-depth, multi-parameter characterization of the particles through digital counting, size determination, and biological phenotyping. Towards this goal: (1) Novel microfluidics will be developed and used for efficient magnetic enrichment; (2) Isolated particles will be detected and analyzed with a novel biological nanoparticle (BNP) sensor (3) Immune-capture and release chemistries as well as phenotyping assays will be developed; (4) Critically, complete on-chip integration of isolation, detection and analysis will be accomplished; (5) Utility of in-depth exosome characterization will be demonstrated with clinical samples for lung cancer. Project INDEX requires successful integration of multiple sub-units and assays that each represents technological frontiers, which is extremely challenging. However, the breadth of information on exosomes that will be available with the integrated system is unmatched. Although, the clinical utility of exosomes is still developing, the uncertainty can only be clarified through automated technologies that provide latitude of information. Once completed, Project INDEX can demonstrate a new paradigm in cancer diagnostics, and also present a potential future technology for other applications involving nanoparticles.

Keywords: digital detection,bio nanoparticles,exosomes,microfluidics,interferometry,magnetic,immunocapturing,optical biosensing
Program Analysis and Reorganization, as a Service (PARSe)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Greece
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2018-10-01
End date: 2020-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The PARSE project will explore the potential for wide deployment (and possible commercialization) of whole-program static program analysis techniques as a web-based service for program comprehension and reorganization. This analysis-as-a-service (AaaS) approach will have direct value for a large number of professional programmers. The programmer will use the service to answer key program comprehension questions (including: “how does my code use this open-source library?”; “Am I affected by the security vulnerabilities discovered in this library code?”; “What objects should I lock before making this library call?”) and to act upon them (e.g., reorganize code and prepare packaged versions of binary code for deployment so that only the minimal needed code is included). Such needs have been identified in direct contact with major software companies (namely, Facebook and Oracle, which are both partners in current projects with the PI’s group). The proposed work lifts such specific coding needs to a general-availability web-based software analysis service. Analysis questions will be answered in high precision, with the aid of the program analysis algorithms developed in the ERC frontier research project (SPADE —307334) that the proposed work draws upon. Past tools in the commercial or research space have focused on high-precision, yet local, analysis. The proposed work will leverage whole-program static analysis techniques (such as pointer, value-flow, and taint analyses) that the PI’s group has extensively developed in the last decade.

Keywords: software,programming,service,program analysis