Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
DEmonstrator of industrial CArbon-free power Generation from Orc-based waste-heat-to-Energy systems (DECAGONE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Efficient, sustainable and inclusive energy use
Action type: Innovation actions
Countries involved: France,Czechia,Greece,Norway,Belgium,Germany,Finland,Tunisia,Switzerland,Slovakia
Call: Industrial excess (waste) Heat-to-Power conversion based on organic Rankine cycles (HORIZON-CL5-2021-D4-01, 2021)
Start date: 2022-06-01
End date: 2026-05-31
Duration (months): 48.0
Total project cost (EUR): 18313657.5
EU funding (EUR): 13986960.0
Participants: 16
Project status: TERMINATED

Energy efficiency of intensive industrial processes and particularly waste heat recovery technologies have been identified by international and regional organization like IEA, EU or ADEME in France as a major game changer for CO2 emissions reduction. The DECAGONE consortium led by ENERTIME proposes a project demonstrating the potential of ORC technology in waste heat-to-power conversion for self-consumption of industrial plants at a large industrial scale. Targeting the waste heat potential of the company TŘINECKÉ ŽELEZÁRNY (mother company of partner Energetika Trinec), located in Czech Republic and historical manufacturer of iron & steel, the DECAGONE project will develop a an innovative ORC-based WHR system using enhanced capture designs and disruptive turbomachinery. The proposed hermetic turbogenerator design will run on innovative active magnetic bearings for increased compacity, higher availability and safety and cost reduction with near-zero maintenance. Dedicated studies improve organic fluids or mixtures for higher stability and improved transposability to other industries. The project will also provide advanced monitoring using innovative probes, IOT and machine learning algorithms for real-time efficiency improvement. Within the scope of the project at 6 others significant industrial sectors will be evaluated in terms of potential market and transposability at the European scale (aluminum, gas-energy, oil&gas, glass, LNG and cogeneration). New financing and business models will also be investigated, supporting long term operations of the erected assets, coping with long-lasting and resilient industrial processes. The use of the ESCO model to contract, finance and operate energy efficiency facilities will be part of the Project preparing for the future operation of the facility by a specialized company. Lastly diffusion of good practices all over Europe will use European partners in the consortium in coordination with Regional energy agencies.

Keywords: next generation orc system,waste heat recovery,demonstrator,increased efficiency,replicability
Creating FUTUre societal RESILIENCE through innovative, science-based co-creation labs (FUTURESILIENCE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Reforming and enhancing the European R&I System
Destination: Reforming and enhancing the European R&I System
Action type: Coordination and support actions
Countries involved: Belgium,Germany,Italy,Bulgaria,Greece,Spain,Sweden,Netherlands,Denmark,Estonia,Norway
Call: An experimentation space for the uptake and use of R&I results for EU resilience and future preparedness (HORIZON-WIDERA-2022-ERA-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 2889406.25
EU funding (EUR): 2889406.25
Participants: 14
Project status: SIGNED

The FUTURESILIENCE project aims to strengthen European economic and social resilience through an enhanced ability to quickly respond to future crises. This will be accomplished by facilitating the fast and effective use of policy relevant research and innovation (R&I) findings for actors at national, regional and local level. The project has four specific objectives: 1) Map existing policy relevant European R&I findings with high potential to inform policy making for economic and social resilience, and to help address societal challenges at local level 2) Define a set of methodologies for testing in how far the identified R&I findings can inform policies addressing national, regional and local needs 3) Implement the testing methodologies through multi-stakeholder experiments across Europe in co-creation with stakeholders from research, policy, economy, civil society organisations as well as citizens 4) Develop a Knowledge Base of the successfully tested research findings with high capacity to inform policy actors and a Toolbox of methods for testing policy relevant research findings FUTURESILIENCE will set up 'Future Resilience Labs' to test policy relevant R&I findings through 10 pilot exercises: three pre-identified working on climate change, migration and the financial crisis and urban planning; and seven selected through an open call. During the experimentation, multiple stakeholders will discuss and test evidence-based strategies tailored to their specific context and matching their local needs, aiming at reducing vulnerabilities and increasing capacities to be prepared for multiple types of possible crisis. The project will be implemented by a robust consortium with know-how in the fields of resilience, R&I policy and crisis management as well as experience with various co-creation and participative methodologies and specifically hands-on experience with foresight, scenario planning, virtual simulation and agent-based modelling.

Keywords: resilience,future preparedness,foresight,co creation
Intelligent Wearable System for Enhanced Personalized Gait Rehabilitation (GaitREHub)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Serbia,Belgium,Greece,Italy,Thailand,Chile
Call: MSCA Staff Exchanges 2021 (HORIZON-MSCA-2021-SE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 1124371.43
EU funding (EUR): 915400.0
Participants: 7
Project status: SIGNED

One common consequence of specific medical conditions such as stroke or other brain injuries, and certain operations, is the need for post event rehabilitation. In many cases, the inability to walk properly requires professionally monitored gait rehabilitation. Gait rehabilitation is important to restore the gait performance of mobility impaired patients and gait training frequency represents a key factor for effective rehabilitation. GaitREHub aims to develop an effective, comprehensive approach to providing targeted home-based gait rehabilitation, by integrating cutting-edge technologies, from the areas of (1) computer-based design and modelling of customized smart insole/socks, (2) wearable sensors and flexible embedded electronics realization, (3) home assistive robots, data analytics and artificial intelligence algorithms development as well as user-friendly software tool for gait rehabilitation, and (4) pre-clinical validation of the developed holistic, integrated and interactive system (our “REHub”). The GaitREHub consortium consists of international recognized institutions and organizations, 4 from academic and 3 from industrial sector, from Belgium, Italy, Greece, Serbia, Chile and Thailand. GaitREHub will facilitate the exchange of knowledge, skills and competencies throughout 199 person-months of carefully planned secondments, promoting international and interdisciplinary collaboration and disseminating the project results to all stakeholders. This interdisciplinary and inter-sectorial project offers an excellent research and innovation environment for the personal and professional growth of the seconded staff members. The outputs of GaitREHub will effectively enhance the personalized rehabilitation of neurologically injured patients and any other patient in need of gait rehabilitation, while also sustaining R&I collaboration within the consortium, developing the potential for commercialization, and working to improve health outcomes for our society.

Keywords: smart insole,smart socks,sensors,flexible electronics,home robots,gait training,rehabilitation
Integrating a Comprehensive European Approach for Climate Change Mitigation and Adaptation in Montenegro Viticulture (MONTEVITIS)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Montenegro,Portugal,Germany,Italy,Luxembourg
Call: Twinning Western Balkans Special (HORIZON-WIDERA-2021-ACCESS-02, 2021)
Start date: 2023-01-01
End date: 2026-03-31
Duration (months): 39.0
Total project cost (EUR): 1492620.75
EU funding (EUR): 1492620.75
Participants: 11
Project status: SIGNED

The principal objective (PO) of MONTEVITIS is thus to strengthen, homogenize and augment UDG and its involved faculties’ and labs’ research and collaboration capacities and performance, both in Montenegro and across the European prospect, in specific topics of climate change mitigation and adaptation in viticulture. Three defined operational topics constitute the pertinent needs of an integrated and operational European approach in tackling climate change in viticulture, now to be applied in Montenegro via UDG. Firstly, the project will set up, integrated, and validate the following topics: 1) use and adaptation of existing analytical and modelling tools for assessing the effects of climate change at regional levels, 2) understanding these effects on the course of physiological processes in the vine, yield, ripening, and quality of grapes and wines of different varieties. MONTEVITIS will then combine a somewhat orthogonal topic coming from the ICT sphere of knowledge for efficiently applying the emerging technologies for enhancing the mitigation and adaptation measures in vineyards: 3) definition of precision viticulture technologies and usage scenarios in vineyard management. The project is built upon the strengths of all of its consortium members and conducts the twining processes in combining the research methodologies with gradually expanding know-how and findings for the benefits of UDG and all participants. MONTEVITIS EU partners are in countries with worldwide recognised viticulture demarcated areas and have years of R&D and innovation experience in viticulture and climate studies. As well as being able to share valuable knowledge and experience, all partners will benefit from research, networking, capacity building, and knowledge transfer processes within this action and ongoing research projects and the general strengthening of many sustainability components. UDG also invited several partners from Montenegro for extending the impact of the project.

Keywords: viticulture,wine production,climate change,computer science,precision viticulture,twinning,knowledge transfer,technology transfer,innovation,sandt capacity and research profile reinforcement
Neuromorphic computing system for real-time signal monitoring and classification with ultra-low-power 2D devices (NEURO2D)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2024-10-01
End date: 2026-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

The detection and classification of electrophysiological signals (EPSs), such as electroencephalography (EEG) and electromyography (EMG) recordings, are the gold standard in neuroscience, enabling the identification of digital biomarkers capable of health monitoring, personalised medicine and advanced brain-computer interfaces (BCIs). The state-of-the-art technology in this field, however, still relies on bulky, inefficient microelectronic systems which relies on artificial intelligence (AI) in the cloud. The energy efficiency and classification accuracy can be largely improved by neuromorphic computing with emerging materials and devices capable of mimicking the neural mechanisms in our brain. This project aims at developing a novel class of neuromorphic systems based on reservoir computing (RC) in charge trap memory (CTM) based on 2D semiconductors. 2D-CTM devices are able to extracted features from EPSs at extremely low power and high accuracy of classification, thus providing efficient biomarkers for medical diagnosis and BCIs. The project will develop the RC system based on the 2D-CTM technology for a broad application space, with the goal of establishing a novel technology platform for scalable, lowpower implantable/wearable chips for real-time EPS monitoring and classification.

Keywords: neuromorphic engineering,2d semiconductors,reservoir computing
OPTimising FORest management decisions for a low-carbon, climate resilient future in EUrope (OptFor-EU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Land, ocean and water for climate action
Action type: Research and Innovation actions
Countries involved: Romania,Austria,Germany,Italy,Lithuania,Netherlands,Norway,Spain,United Kingdom
Call: Enhancing science-based knowledge on EU forests’, including old-growth forests, capacities to mitigate climate change (HORIZON-CL6-2021-CLIMATE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 4289077.5
EU funding (EUR): 4289076.0
Participants: 17
Project status: SIGNED

Significant reductions in anthropogenic emissions and increases in CO2 sinks are needed to meet the 1.5 centigrades threshold for global warming set out in the Paris Agreement and reach the climate-neutrality goal of the European Green Deal by 2050. The CO2 sink provided by forests, including old-growth forests, partially offsets the rise in anthropogenic CO2 emissions, providing a large-scale buffer to climate change. Depending on their characteristics and local circumstances, such as management practices or ecosystem services, forests may range from net CO2 sinks to sources. The project 'OPTimising FORest management decisions for a low-carbon, climate resilient future in Europe (OptFor-EU)' will build a Decision Support System (DSS) to provide forest managers and other relevant stakeholders with tailored options for optimising decarbonisation and other Forest Ecosystem Services (FES) across Europe. Based on exploitation of existing data sources, use of novel Essential Forest Mitigation Indicators and relationships between climate drivers, forest responses and ecosystem services, OptFor-EU has five specific objectives: (1) Provide an improved characterisation of the Forest-Climate Nexus and FES; (2) Utilise end-user focused process modelling; (3) Empower forest end-users to make informed decisions to enhance forest resilience and decarbonisation; (4) Provide a novel DSS service; and (5) Bridging different EU strategic priorities, robust science, and stakeholders in the forest and forest-based sectors. Based on a supply-demand approach, the methodology combines an iterative process of data consolidation, modelling, and co-development of solutions alongside forest managers and other practice stakeholders in all European Forest Types. The DSS will be designed and tested at 8 case study areas, to provide a ready-to-use service, near to operational (TRL7) at European level, while a user adoption and up-take plan will maximise the societal and business impact.

Keywords: forest science,climate change,decarbonisation,forest ecosystem services,decision support system,process modelling,forest management practices,forest climate nexus,climate change mitigation
Non-surgical Repair of Tympanic Membrane Perforations using novel biomaterial implant/delivery system device. (TMRegen)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Ireland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 42.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

"TympanoColl" is a surgical repair kit with 2 discrete parts; (i) a novel bilayered regenerative biomaterial implant, supplied within (ii) a bespoke delivery device, specifically optimised to deliver the biomaterial implant directly via the ear canal. The bilayered biomaterial implant is the 1st critical component of the all-in-one system. It is comprised of 2 layers. The 1st is a thin-film regenerative membrane layer that is attached on top of an underlying supportive porous biomaterial scaffold layer. This bilayered implant has optimised previously to drive rapid cell infiltration & coverage once implanted. It actively directs migration of the patient’s own host cells to stimulate seamless regeneration of the damaged portion of the eardrum. The use of the underlying porous scaffold replaces the need for off-the-shelf synthetic packing materials. The 2nd critical component is the delivery system to simplify in-ear delivery & improve procedure outcome by standarising the approach.

Keywords: medical device,ear,nose and throat ent surgical device,bioimplant
Venetian Historiography and Public Credit 1200–1600 (VenHisCred)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria,United States
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 230184.72
EU funding (EUR): 230184.72
Participants: 2
Project status: SIGNED

VenHisCred is the first comprehensive and comparative analysis of the emergence of public credit as a subject for Venetian civic historiography. Examining the nexus between public credit, state formation, and historiography from the 13th to the 16th century, it asks why Venetian chroniclers started to include descriptions of public credit in narratives of the political past and investigates how they represented the relationship between state borrowing and state formation. Undertaken at the Department of Economic and Social History (WISO), University of Vienna (UNIVIE) with a training secondment at Harvard University, the project develops an innovative interdisciplinary approach combining digital corpus linguistics with close contextual reading to analyse the emergence of new discursive topics in large bodies of texts. In Venice, public credit was fundamental in raising emergency money for military expenditure. Whilst forced and voluntary loans and annuities funded state expansion, these credit instruments also enabled families to preserve wealth, ascend socially, and mobilize capital for welfare. However, we know little about Venetians’ own subjective understanding of the role of credit in political life. VenHisCred uncovers these ideas through Venice's vast corpus of chronicles. The project develops an innovative new methodology that uses digital text analysis and close reading to analyse this large corpus of texts. VenHisCred will make available a new digital corpus, a database of 2200 citizen creditors from newly discovered statistics, and result in a peer reviewed journal article on narrating public credit in medieval and early modern Venice.

Keywords: fiscality,economic thought,renaissance
Towards the clinical implementation of TREM2 Microglia Engineering for treating DementiaS (TREM2MEDS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Italy,Czechia,France
Call: EIC Transition Open 2023 (HORIZON-EIC-2023-TRANSITION-01, 2023)
Start date: 2024-04-01
End date: 2027-03-31
Duration (months): 36.0
Total project cost (EUR): 2499721.25
EU funding (EUR): 2499721.25
Participants: 4
Project status: SIGNED

TREM2MEDS emerges from the ERC PoC 2022 project TREM2μENGINES (Grant agreement ID: 101069395), which validated the efficacy of a novel treatment for Alzheimer’s Disease (AD) and Nasu-Hakola Disease (NHD) in murine models. A relevant proportion of AD cases and all forms of NHD are caused by pathogenic mutations in the TREM2 gene, which lead to microglia dysfunction contributing to and/or causing the onset and manifestations of AD and NHD. TREM2MEDS approach involves the transplantation of hematopoietic stem/progenitor cells (HSPCs) engineered by lentiviral vectors (LVs) to express robust levels of the Triggering receptor expressed on myeloid cells 2 (TREM2) in their central nervous system (CNS) myeloid/microglial progeny. The engineered cells have shown the ability to reduce and prevent Aβ accumulation, mitigate neuroinflammation and restore physiological scavenging functions in the diseased CNS, benefiting AD and NHD in robust animal models. In TREM2MEDS, we will exploit these findings for transition of the approach from TRL 4 to TRL 5/6 by generating IMPD-enabling data and packages that will allow launching, at project completion, a first-in-human Phase I clinical trial of TREM2-HSPC gene therapy in AD & NHD patients carrying TREM2 hypofunctional variants. The restoration of TREM2 function in microglia, by intervening on key mechanisms contributing to neurodegeneration, has the potential to overcome the limited efficacy of current treatments for AD, which only exert symptomatic but not curative effects. Through this work we will thus bring to clinical testing an approach intended to become the benchmark in the treatment of AD and NHD, and possibly other dementias.

Keywords: neurodegenerative diseases,gene therapy,neuroinflammation,hematopoietic stem cells,trem2 gene,a accumulation