Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Development of a European Multilingual LLM for legal and regulatory text and its integration with the structured legislation repository (Aptus.AI platform)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Regulatory compliance in Europe is complex due to the region's stringent, diverse, and dynamic legal landscape. Companies face challenges in navigating various national regulations and sector-specific laws like GDPR, MDR, and IVDR, often leading to high costs, resource-intensive processes, extensive documentation requirements, and risks of non-compliance. Compliance management requires significant financial investment, especially for staffing, training, and maintaining compliance systems. The lack of automation in managing legal documents and tracking regulatory changes creates inefficiencies, errors, and additional costs. Aptus.AI addresses this unaddressed need by automating the extraction and enrichment of legal data, making compliance processes faster, more accurate, and scalable. Leveraging proprietary AI models, the platform organizes legal texts into structured, machine-readable formats adhering to the Akoma Ntoso standard. By utilizing advanced AI techniques, Aptus.AI reduces the manual burden of compliance management and enhances the analysis of regulatory documents, embedding crucial non-textual elements such as legal definitions, obligations, and penalties for comprehensive compliance insights. The platform offers substantial cost savings, increased resource efficiency, simplified documentation, and reduced risks of non-compliance. Additionally, Aptus.AI provides real-time legal updates, customized regulatory frameworks, and proactive regulatory trend insights across multiple industries, ensuring consistent and accurate compliance. Under the EIC project, we will optimize a multilingual legal LLM aligned with knowledge graphs to reduce AI hallucinations, develop a RegTech-as-a-Service platform for startups and companies, and scale commercialization efforts. This will enhance the platform’s AI models, improve multilingual capabilities, and allow us to expand market reach across Europe and globally.

Keywords: legal system,regulatory compliance,big data
SUSTAINABLE UPCYCLING OF AGRICULTURAL BYPRODUCTS INTO ENHANCED PROTEINS FOR OPTIMAL NUTRITION OF ANIMALS (ProteinBoost)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Poland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499999.99
EU funding (EUR): 2499999.99
Participants: 1
Project status: SIGNED

Increasing local protein production in the EU is essential to reduce dependence on imported protein sources, improve food security, and support the EU’s sustainability goals under the Green Deal. At Proteine Resources, we have developed an efficient method to handle yet unprocessed agricultural byproducts, formally considered waste (a stable side-stream available 365/7) into valuable insect-based products. When properly catered for, the deliberately selected insect species feed on a side-stream, retaining its exceptional nutritional value and delivering protein exceeding 80% of the defatted content. Our solution surpasses alternatives like soya and offers a digestibility level comparable to egg or whey protein. The high-quality outputs can be used in animal feed, targeting demanding markets like premium poultry, pet food, and veterinary supplements, providing significant animal health benefits. Also, we tested frass (insect excrement) to be used as fertilizer by side-stream suppliers, demonstrating true circularity. Achieving this required innovations in insect feed composition and rearing process control, which involves advanced multispectral analysis necessary to autonomise and optimise production resulting in patentable know-how. Our prototype low-capacity working station and successful laboratory tests garnered interest from side-stream suppliers and potential buyers of insect-based products. Through the EIC Accelerator project, we're poised to enhance our technological solution by refining enabling technologies and developing a first-in-the-world pilot autonomous insect farm module offering unparalleled efficiency and sustainability of the production process. The decentralised approach will significantly boost our insect-based production capabilities, positioning us to tap into the €1.34B global market. We are confident that our solution will contribute to the EU's strategic autonomy, improve sustainability, and curb CO2 emissions, making a substantial impact.

Keywords: insect protein,multispectral imaging,food security,agricultural byproducts,bio waste processing,autonomous farming,circular value chains,sustainable agriculture
Aliphatic Polyurethane via Reactive Injection Moulding: the most advanced and sustainable Solid Surface Material on the market (Arcesso Solid)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 48.0
Total project cost (EUR): 2100000.0
EU funding (EUR): 2100000.0
Participants: 1
Project status: SIGNED

Arcesso Dynamics was established in 2009 as a developer, manufacturer and seller of high value-added Polyurethanes for polymer parts for a wide range of applications (cash machines, lamps, charging stations for electric vehicles…). Fuelled by a vision of becoming a leading innovator of sustainable advanced polymeric materials on a global scale, we have invested in R&D that has led to the invention of a multi-award-winning Aliphatic PU material that for the very first time makes it possible to injection mould PU for Solid Surface parts via a streamlined Reaction Injection Moulding (RIM) process. To date, it has not been possible to manufacture Solid Surface parts from PU due to a series of limitations (e.g. shrinkage effect during processing leading to visible defects in the final part, ‘yellowing’ of the final product). The patented Arcesso Solid® innovation overcomes these limitations and is the long-awaited disruptor in the Solid Surface Material (SSM) market as a materials and manufacturing breakthrough. Our new material offers a unique set of properties (hardness, impact resistance, heat & chemical agent resistance, colour pallet, non-slip, photocatalytic, antimicrobial) and unprecedented versatility of complex design vs. conventional SSMs (that are currently limited to simple forms like kitchen tops, shower plates). Our manufacturing process reduces cycle times, energy consumption and carbon footprint for competitively manufacturing a whole new range of previously unobtainable PU injected complex geometric designs (medical devices, lab instruments, urban furnishings, etc.) offering improved technical performance, sustainability & environmental credentials that outperform their conventional Acrylic resin or Isophthalic resin based counterparts. Arcesso Solid® puts us at the doorway of a growing (CAGR 9.8%) global cast polymers & SSM market (US$35 billion by 2026), in which there are major market, political & consumer drivers for the adoption of our innovation.

Keywords: aliphatic polyurethane reactive injection moulding solid surface materials
Plexigrid: Plexar Operated Grids (Plexigrid)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain,Sweden
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2024-06-01
End date: 2026-05-31
Duration (months): 24.0
Total project cost (EUR): 3512000.01
EU funding (EUR): 2450000.0
Participants: 2
Project status: SIGNED

Plexigrid - Plexar Operated Grids Plexigrid is creating a new value chain since it is building the Operating System for tomorrow's electricity grid. This system enables a new value chain for electricity distribution, where producers, consumers, grid operators... and their devices (EVs, heat pumps, batteries, AC units, solar PV, transformers, smart meters...) interplay in real time to optimise energy usage and the utilisation of the electricity grid infrastructure. By automatically adapting the flexible consumption/production/storage of these players, this dual "grid+energy" optimisation would reduce hundreds of billions of euros annually in energy savings and grid fees. The elements of this future value chain are already there (consumers, producers, retailers, grid operators... and their wind, solar, PV, EVs, heat pumps, AC units, batteries, smart meters...), but the real time synapsis and orchestration of these hundreds of millions of devices requires a layer of intelligence which does not exist today. Our solution is a new “grid operating system” that makes electricity distribution grids fit for the energy transition, i.e., fit for a safe, intelligent and efficient orchestration of the hundreds of millions of EVs, heat pumps, PV panels,… that electricity grid operators will have to host in their grids. Our technology provides grid operators with 3 superpowers: 1) ARI- Real-time visibility across the whole network (today grid operators have limited to no visibility below 20,000 volts, where the vast majority of the new demand has to be hosted) 2) TATARI- Real-time grid analytics (grid operators lack real-time analytics under 20,000 volts) 3) TIA- Real-time access to flexibility (i.e. to the flexible scheduling EV charging, heat pumps,…) Our solution enables an optimal use of grid capacity and saves hundreds of billions of € in CAPEX/OPEX for grid operators and their customers.

Keywords: digitalization,energy transition,electrical distribution systems,energy efficiency,electrification,flexibility,digital twins,artificial intelligence
Conceptualization and operationalization of minorities in the practice of UN treaty bodies (MINCOOP)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Slovenia
Call: ERA Fellowships (HORIZON-WIDERA-2023-TALENTS-02, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 171399.36
EU funding (EUR): 171399.36
Participants: 1
Project status: SIGNED

MINCOOP is an interdisciplinary and intersectoral project that focuses on the conceptualization and operationalization of minorities under universal international law, with the ultimate purpose to improve the legal protection of traditional (national, ethnic, religious, linguistic) minorities and persons belonging to them. The project contributes to a growing area of minority studies, setting out from the recognition that international law routinely operates with the concept of minority when providing standards for the recognition of group-specific rights or protection from discrimination, without actually offering definitions on the protected groups (conceptualization) or membership criteria therein (operationalization). This in not merely an unresolved theoretical issue, but a practical deficiency with crucial importance for the protection of minorities. Namely, ambiguity in the relevant terms hampers the achievement of policy goals, and the potential for abuse easily leads to further discrimination and marginalization. In order to give definite answers to the problems of conceptualization and operationalization, the project proposes to carry out an up-to-date, systematic and comparative analysis of the monitoring materials of the ten UN human rights treaty bodies – thus filling an important gap in scholarship. The project follows a mixed-method research design including quantitative, computer-assisted content analysis and qualitative legal analysis, as well as case studies and field research (interviews) conducted in Slovenia. The research project will not only inform the theoretical debate on minority rights and provide recommendations for policy-making, but also intends to raise awareness of the pressing issues of traditional minorities among the general public, promoting more tolerant, inclusive societies.

Keywords: un human rights treaty bodies minorities minority rights conceptualization operationalization
Epigenetic methylation-based diagnostics to accurately distinguish between common dementias in the clinic (DECIPHER)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Dementia presents a pressing global challenge with staggering economic implications, affecting over 55 million individuals worldwide and imposing a burden exceeding 1.3 trillion dollars annually. Timely and accurate diagnosis is vital for effective symptom management, patient well-being, and alleviating the burgeoning economic burden. However, current diagnostic methodologies hinder optimal patient care and exacerbate healthcare costs through its limited reliability and inaccurate diagnoses. Our DECIPHER project aims to revolutionize dementia diagnosis by introducing an advanced epigenetic-based companion diagnostic tool. Unlike existing tests, our platform leverages unique methylation biomarkers in mitochondrial DNA, enabling clinicians to distinguish between different dementia types with unprecedented accuracy. Through rigorous validation and machine learning algorithms, our platform ensures robust analysis and multi-classification, empowering clinicians to make confident diagnoses. The DECIPHER project not only addresses the critical need for reliable diagnostic tools but also offers a comprehensive solution encompassing a user-friendly interface and sophisticated backend. Our business model, anchored by strategic partnerships and regulatory insights, facilitates swift market entry and adoption. With a targeted approach to marketing and revenue projections reflecting substantial market potential, ADmit Therapeutics is poised to make a significant medical and economic impact in the dementia diagnostics.

Keywords: dementia with lewy bodies,alzheimer s disease,parkinson s disease,diagnostics,machine learning,epigenetics,blood based biomarkers
Armenian Trading Communities between Amsterdam and Venice, 1650-1730 (ARMAVen)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 187624.32
EU funding (EUR): 187624.32
Participants: 1
Project status: SIGNED

Armenian merchants, translators, and brokers were critical actors in the global trade of luxury goods between Asia and Europe in the seventeenth and eighteenth centuries. They were able to move and settle in cities across Europe with relative facility, facing comparatively fewer political barriers than Jewish or Muslim traders due to their status as a Christian-majority trading group. However, the current historiographical picture of these communities in Western Europe has not adequately illustrated or understood the complexity of what ‘trading community’ really meant for Armenians, and other mobile minorities; it often assumes a level of cultural cohesiveness within these groups. How should we understand the concept of community when it is shaped by circumstance, conducted over distance, formed of both transient and settled members, and interacts with the host environment? This project investigates this question by a comparative analysis of the Armenian communities of early modern Amsterdam and Venice, and the un-explored mercantile networks between them. New archival research redresses the historiographical neglect of these two communities and their connection to shed new light on the conceptual and practical formation of trading community. Integrating the theoretical paradigms of social and spatial mobility, and crossing the disciplines of history, sociology, and human geography will advance a new nuanced concept of minority community from the early modern period to the present.

Keywords: 17 18th centuries merchants trade political negotiation cultural identities trading diaspora minority communities
Hydrogel containing Metal-Organic Polyhedra as scaffold agents for in vivo local gas delivery in glioma cancer tumours (GLIOTARG)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal
Call: ERA Fellowships (HORIZON-WIDERA-2024-TALENTS-02, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 207183.12
EU funding (EUR): 207183.12
Participants: 1
Project status: SIGNED

The National Brain Tumor Society of America stated that glioblastoma is one of the most complex, deadly, and treatment-resistant cancers with an average length of survival of 8 months. Surgery is the primary form of treatment, and some drugs are approved for treatment, however, none of these treatments have significantly extended patient lives beyond extra months. Recurrence following surgery is a major problem and is often the ultimate cause of death. Accordingly, our specific aim is to target glioma cells with gas- Metal-Organic Polyhedra (MOP) conjugates after/before surgery removal of the tumor in in vivo mice models of glioblastoma cancer. Therapeutic gases (i.e. CO and NO) will be absorbed in the MOP cavity, while the surface will be functionalized for tumor targeting. The system will be dispersed in a biodegradable hydrogel, that will assist in the progressive delivery into the tumor cells once it is injected into the brain. Hydrogel will be tested as a gas-MOP system dispersion medium and as a conjugated treatment including already-known chemotherapeutic drugs for glioma (i.e., Temozolomide, Carmustine or Bevacizumab). The ultimate goal of the project is to create a patch made of bioresorbable hydrogel containing drug and MOP-gas conjugates for local release in glioblastoma tumoral cells. This dual system will be specifically and locally delivered in tumor cells by functionalization of MOP linkers to target and attach to the tumor. To the best of our knowledge, this is the first time that (i) Metal-Organic Polyhedras (MOPs) are used in cancer therapy as carrier systems and (ii) a combined treatment gas/drug is applied for glioblastomas to eliminate or reduce the tumor before/after surgery removal. This proposal achieves the aims of the European Research Area and is highly relevant to the Marie Curie Programme and to long-term career development.

Keywords: hydrogel metal organic polyhedra no co gas drug delivery scaffolds nanomedicine nanotherapy glioblastoma
Tight Alright by FeelTect: A wearable, connected-health technology and digital platform to optimise venous leg ulcer treatment. (Tight Alright)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Ireland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 36.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Tight Alright by FeelTect is a wearable, connected-health technology and digital platform to optimise venous leg ulcer treatment, which will empower patients to manage their health using enhanced telemedicine features that enable continuous monitoring by patients with the support of their carers. This provides a technologically advanced solution to meet the evolving needs of saving costs in the healthcare system. Venous Leg Ulcers (VLUs) affect 11.5M people worldwide and cost EU healthcare systems €14B every year. Compression therapy, i.e., the application of pressure on the leg via bandages, is the first-line therapy for VLUs. However, optimal pressure is not achieved in 90% of cases and regular visits for several weeks are required to monitor and reapply compression. To address this clinical need, Tight Alright will seamlessly monitor the level of compression throughout treatment, enhancing healing times and reducing the need for clinical visits, which will have a positive environmental impact and will reduce healthcare costs. Continuous monitoring allows healthcare providers to ensure the prescribed pressure is being consistently applied in accordance with personalised patient needs. Tight Alright is a comfortable wearable device that can continuously monitor sub-bandage pressure in real time. An integrated Digital Platform (DP) analyses the captured data via user-friendly interfaces for clinicians and patients to guide and monitor the consistent application of gold-standard compression to impact healing times. Furthermore, accumulated data on pressure and treatment outcomes can be used, for the first time, to inform data-driven optimisation of compression therapy, enabling disruptive improvements to the standard of care. This is particularly important for our aging populations and the increasing prevalence of chronic conditions, which contributes to a growing demand for effective wound care.

Keywords: personalised treatment compression therapy venous leg ulcers healthy ageing
Biotechnology Harnessing Immortal Genetics (OCorp)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Ireland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 36.0
Total project cost (EUR): 1000000.0
EU funding (EUR): 1000000.0
Participants: 1
Project status: SIGNED

OCorp has discovered powerful antimicrobial Defensins in the Olive Seed in a public private research program with TUD, that indicate far more potent antimicrobial activities than the existing anti microbial treatments on the market. This discovery can potentially reform pharmaceutical treatment for anti microbials and anti fungals, while it can also have a major impact on Anti Microbial Resistance.

Keywords: anti microbial resistance anti fungals biotech