Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
3D printed elastomers with stereochemically-defined properties (STEREOM3D)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: Call for proposals for ERC Proof of Concept Grant (ERC-2020-PoC, 2020)
Start date: 2021-04-01
End date: 2023-03-31
Duration (months): 24.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

In most synthetic polymeric materials, control over the mechanical properties of the material is achieved by changing the fundamental chemical structure of the polymer by using monomers with fundamentally different functional groups, chain length or rigidity. In contrast, Nature’s polymers use a more restricted set of building blocks but use additional complexity to the structure−property relationship by leveraging stereochemistry to control the structure and hence properties and function of materials. Through the STEREOPOL ERC programme, we have been investigating this relationship and how to both overcome the synthetic limitations that hold back the design of stereoregular materials, as well as how these fundamental properties can be used to influence materials properties and behaviour. Within this project, and inspired by the cis/trans stereochemistry that dictates the enormous differences in mechanical properties between the otherwise structurally identical gutta percha and natural rubber, we have discovered that E/Z isomerisism within double bonds in synthetically-accessible polymers can be used to control mechanical properties of the resultant thermoplastic elastomer materials. Through this work, we have identified that these principles can be extended to photoset materials (those that are crosslinked by exposure to light), while retaining their elastomeric nature. In turn, this advance enables us to develop the first 3-dimensional (3D) printed elastomers with material properties that are determined by stereochemical composition. The ability to control materials properties by stereochemical leverage will reduce the need to reformulate each composition for processing by 3D printing, thus providing a significant commercial advantage in an area in which competitive materials are limited but in which there is a significant need.

Keywords: polymer,stereochemistry,3d printing
Slave Testimonies in the Abolition Era. European Captives, African Slaves and Ottoman servants in 19th century North Africa (SlaveVoices)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: France
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-10-01
End date: 2026-09-30
Duration (months): 84.0
Total project cost (EUR): 1999975.0
EU funding (EUR): 1999975.0
Participants: 1
Project status: SIGNED

SLAVEVOICES has two main groundbreaking scientific goals. First, it aims at fully renewing our approach of the end of slavery, a crucial social transformation in North Africa as a part of the Muslim world. So far historians have explained the abolition and slow vanishing of slavery in this region either as the outcome of European imperialistic interventions or to a lesser extent as resulting from debates among Muslim scholars and leaders who were owning slaves. SLAVEVOICES will instead interpret the end of slavery through the testimonies of the ones who experienced and acted for the end of slavery: namely the testimonies of the slaves and their descendants written in Arabic, Ottoman Turkish and European languages. Second, by studying together –and not apart as is often the case– the various groups of slaves in North Africa hailing from Africa, Europe and Asia, SLAVEVOICES will propose a new way of conceiving and writing the history of North Africa. Instead of studying each historical phenomenon according to each national part of this region (Morocco, Algeria, Tunisia, Egypt) as it is has often been the case, SLAVEVOICES will be a concrete attempt at writing a globalized and connected history of modern North Africa. It will explore the reshaping of the connections that groups of slaves built up within North African societies and between this part of the Muslim world and other adjoining societies in Africa, Asia and Europe in the abolition era. SLAVEVOICES will innovate in resituating slave testimonies within a broader history of literacy in North Africa throughout a long nineteenth century, a period in which literacy and written sources underwent major changes in Ottoman and colonial North Africa. Finally through a website, a book, a play, and videos SLAVEVOICES will bring back the voices, the speeches and emotions of nineteenth century slaves to a present audience as new forms of enslavement and social dependency are resurfacing across the Mediterranean.

Keywords: slavery,north africa,ottoman empire,abolition,testimonies ego documents
EuRopEAn incubator for trusted and secure data value CHains (REACH)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Estonia,Spain,Italy,Spain,Spain,Spain,Ireland,Belgium,Türkiye,Greece,France,France,France,France,Portugal,United Kingdom
Call: Big Data Innovation Hubs (H2020-DT-2019-2, 2019)
Start date: 2020-09-01
End date: 2024-02-29
Duration (months): 42.0
Total project cost (EUR): 7510961.26
EU funding (EUR): 6999306.0
Participants: 23
Project status: SIGNED

Europe has an opportunity to have a leading position on Data Economy, particularly in B2B scenarios. Special focus must be placed on accessing, sharing and reuse of data in an environment of security and Trust, which are fundamental preconditions for the Data Economy. The support of pilot projects and innovation spaces for experimenting with cross-sector multi-stakeholder data innovation is therefore urgent. Efforts need to concentrate on the provision of trusted and secure privacy-aware analytics solutions allowing for the secure sharing of proprietary industrial data along with personal data. REACH aims to launch a sustainable European-wide second-generation incubator for data-fuelled start-ups & SMEs aiming to develop innovative experiments within data value chains. REACH will launch 3 Open Calls expecting to attract +500 data driven concept-applications and select 100 business ideas to undertake a 4-phases funnel Tech-Biz acceleration programme (EXPLORE - EXPERIMENT - EVOLVE - EXPOSE). REACH aims to support the generation of new data-fuelled products & services, drive the development of solid businesses, trigger revenue growth and foster the access to new funding rounds, by offering a full service pack consisted of: tech-training and experts, datasets, technological bricks for secure and trusted data value chains, computing infrastructures, business development training & coaches and up to €120k equity-free funding. REACH will demonstrate that Data Silos can be broken by enabling a multi-stakeholder cross-sectorial incubator to boost data-fuelled sustainable solutions, leveraged by the capacities of the best data-driven DIHs in Europe. Besides a solid consortium to access world class startups/ SMEs and deliver high valuable technological & business services, REACH integrates 3 DIHs and 9 public/ private data-providers and 2 private investor brokers. We aim to generate 10M€ volume investment for SMES creating 15 data value-chains delivering fit-to-market products

Keywords: trusted and secure data value chains,data market,common european data space
Decision Support for the Supply of Ecosystem Services under Global Change (DecisionES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,Spain,Spain,Finland,Sweden,United States,Portugal,Portugal,Canada,Chile,Costa Rica,Brazil
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2020, 2020)
Start date: 2021-07-01
End date: 2025-06-30
Duration (months): 48.0
Total project cost (EUR): 2401200.0
EU funding (EUR): 2212600.0
Participants: 17
Project status: SIGNED

Pressures on forest ecosystems are very likely to increase as a consequence of socioeconomic and demographic trends. A growing population will demand more products (e.g., wood) to be extracted from forest ecosystems. At the same time, these harvesting activities and their interactions with global change drivers will impact the sustainability of the supply of a wider range of non-provisioning services (e.g., wildfire protection, water, and biodiversity). The integrity of ecosystems must be safeguarded when developing harvesting activities, and yet this is further complicated by the occurrence of natural disturbances such as wildfires and droughts, etc. New decision support approaches are needed that can cope with this challenge. European and the American experiences with the development and application of decision support approaches for the provision of ecosystem services (ESs), offer a solid base for continued improvement in the efficiency and effectiveness of forest management in the context of global change (e.g., responding to changes in demographics, socioeconomics, and climatic conditions). This provided the rationale for a project that will help to strengthen research collaboration through active networking and staff exchange between 8 European organizations and 10 American organizations that are leaders in these fields. This project will build from the top-level multidisciplinary expertise (wildfire ecology and management, wildfire behaviour simulation, hydrology, process-based modelling, biodiversity, wildlife management, ecology, water services, operations research, management science, stakeholder engagement, forest ecosystem management planning methods, supply chain management methods and decision support systems) in these organizations to address the integration of operational, tactical and strategic forest ecosystem management planning levels and potentiate the supply of ecosystem services at various spatial and temporal scales.

Keywords: decision support,decision making,forest planning,global change,forest fires,climate change,adaptive management
INnovative Tools for Assessment and Authentication of chicken meat, beef and dairy products’ QualiTies (INTAQT)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Research and Innovation actions
Countries involved: Italy,Germany,Spain,Ireland,Italy,Italy,Italy,Italy,Germany,Italy,Belgium,Switzerland,Switzerland,Poland,France,France,France,France,France,United Kingdom,Portugal
Call: Husbandry for quality and sustainability (H2020-FNR-2020-2, 2020)
Start date: 2021-06-01
End date: 2026-05-31
Duration (months): 60.0
Total project cost (EUR): 6155318.75
EU funding (EUR): 6126650.5
Participants: 25
Project status: SIGNED

Agri-food chain actors lack objective, robust and reliable information to meet consumer expectations in relation to the multiple aspects of intrinsic quality of livestock products from the various European husbandry systems. The goal of INTAQT project is to perform an in-depth multi-criteria assessment of the relationships between husbandry systems and intrinsic quality traits of animal-sourced products. This will be achieved through the development of quality assessment and authentication tools, to provide science-based decision support for policy makers, industries, farmers and consumers as well as develop means to improve husbandry practices complying with high quality of animal products and sustainability of production, defined as the "One Quality" of products. INTAQT will focus on unprocessed and processed ready-to-eat chicken meat, beef, and dairy products stemming from a gradient of extensive to intensive husbandry systems from a wide variety of European countries. The project will use a multi-actor participatory approach, involving all actors of the agri-food chains from farmers to consumers, scientists, certification bodies, policy makers and citizens. The challenges addressed are to: i) develop comprehensive models quantifying the impact of husbandry systems on quality traits related to product safety, nutritional value and sensory features, ii) co-construct with agri-food chain actors rapid and cost-effective innovative and practical analytical tools for the prediction of the intrinsic quality of livestock products and authentication of the associated husbandry systems, iii) co-construct with agri-food chain actors, multi-criteria scoring tools of the intrinsic quality of products, and iv) using all these developed tools, promote innovative husbandry practices (approved by agri-food chain actors) to achieve consistently and verifiable excellent quality, safe, healthy and tasty animal-based products from both extensive and intensive husbandry systems.

Keywords: intrinsic quality,safety,nutritional value,sensory features,chicken and beef meat,dairy products,multi criteria assessment,husbandry practices,intensive,extensive
Towards prevention of autoimmune diseases: the case of rheumatoid arthritis (PREVENT RA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Sweden
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-04-01
End date: 2022-02-28
Duration (months): 47.0
Total project cost (EUR): 1582061.0
EU funding (EUR): 1090684.69
Participants: 2
Project status: CLOSED

A common feature of autoantibody-positive autoimmune disease is that the disease-associated autoimmunity often appears many years prior to clinical onset and can hence be used to identify risk groups for future disease development. Autoantibody-positive (seropositive) rheumatoid arthritis (RA) provides a unique setting due to recent insights in the longitudinal development of the disease, suggesting that autoantibodies develop in genetic susceptible individuals as a consequence of specific environmental challenges (such as smoking) to only later on target the joints. The main objectives of the current program are: (1). To dissect the longitudinal development of seropositive RA and gain a detailed understanding of the processes responsible for autoantibody generation outside the joints, and specifically at the mucosal sites. (2). To develop new ways to identify seropositive disease-susceptible individuals and map targetable life style factors and immune events responsible for this susceptibility. (3). To elucidate the mechanisms by which systemic autoimmunity targets the joints to first induce bone loss and pain and only in a second phase chronic joint inflammation. If successful our project will not only allow efficient identification of RA-susceptible individuals, but also deliver new tools for risk estimation in each of these individuals and novel ways of intervention in order to delay, or in the best case prevent disease development. By shifting the time (to phases before joint damage and disability occurs) and the ways (to drugs targeting early previously unknown pathogenic mechanisms) of interventions, expected results from the current project are beyond the current state of the art in RA.

Keywords: rheumatoid arthritis
Gangs, Gangsters, and Ganglands: Towards a Global Comparative Ethnography (GANGS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Switzerland,Denmark
Call: ERC Advanced Grant (ERC-2017-ADG, 2017)
Start date: 2019-01-01
End date: 2024-06-30
Duration (months): 66.0
Total project cost (EUR): 2875893.75
EU funding (EUR): 2307409.0
Participants: 2
Project status: SIGNED

Gangs occupy a key position in the global imaginary of violence, widely perceived and represented as primary sources of brutality and insecurity. This can be related to the fact that they are one of a small number of truly global phenomena, found in almost every society across both time and space. At the same time, however, as almost 100 years of gang research have highlighted, the phenomenon can vary significantly in form, dynamics, and consequences. While there have been many insightful studies of gangs, the overwhelming majority have focused on a single group or location, and we still lack a proper sense of what kinds of gang dynamics might be general, and which ones are specific to particular times and places. The GANGS project will develop a systematic comparative investigation of global gang dynamics, to better understand why they emerge, how they evolve over time, whether they are associated with particular urban configurations, how and why individuals join gangs, and what impact this has on their potential futures. It will draw on original ethnographic research carried out in multiple locations, adopting an explicitly tripartite focus on “Gangs”, “Gangsters”, and “Ganglands” in order to better explore the interplay between group, individual, and contextual factors. The first will consider the organisational dynamics of gangs, the second will focus on individual gang members and their trajectories before, during, and after their involvement in a gang, while the third will reflect on the contexts within which gangs emerge and evolve. Research will combine innovative collaborative ethnography in Nicaragua, South Africa, and France, a ground-breaking comparison of 35 individual gang member life histories from across Africa, Asia, Europe, North and South America, and unique joint ethnographic investigations into the political economy of three gang-affected cities in Nicaragua, France, and South Africa.

Keywords: gangs,life histories,ethnography,comparison
HeartRater: Tools for the systematic evaluation of interoceptive ability (HeartRater)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom,United Kingdom
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-10-01
End date: 2018-03-31
Duration (months): 18.0
Total project cost (EUR): 149630.0
EU funding (EUR): 149630.0
Participants: 2
Project status: CLOSED

The Proof-of-Concept grant seeks to develop a commercializable platform to quantify how sensitive individuals are to their own heartbeats. This platform will have applications in clinical psychology, personalized medicine and beyond. We each differ in the way we express or control our emotions, in the way we base our decisions on feelings, and react to stress or excitement. A key determinant of these aspects on our behaviour is our sensitivity to changes in the emotional arousal of our bodies. Faster stronger heartbeats accompany threat and other challenges, but this may translate as anxiety, sadness or anger depending on how we register and interpret these changes. This Proof-of-Concept grant aims to verify the innovation potential of the ideas and methods linked to the ERC advanced grant 324150 ‘Cardiac Control of Fear in the Brain’. HeartRater will characterise an individual along dimensions of interoceptive ability, including the unique interaction between heartbeat signals and the processing of threat and fear. The Proof-of-Concept of grant will consolidate intellectual property rights and strategy, develop a technical prototype and undertake groundwork for marketing.

Keywords: anxiety,commercialisation,decision making,emotion regulation,proof of concept,screening,software application
MUCOBIOME-MEDIATED IMMUNE PATHWAYS IN INFLAMMATORY BOWEL DISEASES (MUCO-IMMUN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Luxembourg
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-05-01
End date: 2023-04-30
Duration (months): 24.0
Total project cost (EUR): 166320.0
EU funding (EUR): 166320.0
Participants: 1
Project status: SIGNED

Inflammatory Bowel Diseases (IBD) are chronic disorders characterized by persistent ulcerations in the gastrointestinal tract, drastically affecting the patient’s quality of life. Initially regarded as “Western diseases”, they have now become a global problem. Despite IBD being a set of inflammatory diseases, the underlying host immune pathways remain unclear, making it difficult to reliably treat and cure patients. The low-fiber Western diet, and the microbial communities that live in our intestines (the gut “microbiome”), have been proposed as major environmental contributors of the disease - but the mechanisms of their contribution are poorly understood. Among the gut microbiome, the mucobiomes are defined as the microbial communities enzymatically geared to digest the host intestinal mucus layer – our first line of defense against invading pathogens. Their mucolytic activities are regulated by dietary fibers. Thus, we hypothesize that, under a low-fiber diet, the mucobiomes catalyze important disease-promoting immune pathways of IBD. Using an original animal model combining genetic susceptibility, dietary fiber deficiency and different microbiota compositions, we aim at highlighting (1) the role of the mucobiome in IBD pathogenesis, and (2) key immune-pathways regulated by the mucobiome. These objectives are ambitious, yet highly feasible given the expertise of the actors. The proposed work provides a unique dimension to understand the underlying pathogenic mechanisms of a key physiological trait of gut bacteria: host-secreted mucus degradation. The success of this project relies on a close interdisciplinary collaboration that will benefit to develop the researcher's career, the hosting group’s projects, the hosting institute's visibility, and establish innovative diet-based therapies for IBD patients.

Keywords: gastrointestinal mucus system,dietary fiber,host microbiota interactions,human gut microbiota,inflammatory bowel diseases,mucobiome,synthetic microbiota,diet