Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Remote area Access Network for 5th GEneration (5GRANGE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Finland
Call: 5G Networks (H2020-EUB-2017, 2017)
Start date: 2017-11-01
End date: 2020-10-31
Duration (months): 36.0
Total project cost (EUR): 999906.25
EU funding (EUR): 999906.25
Participants: 4
Project status: CLOSED

5G is considered the next revolution in communication. Several researches focus efforts in tackling challenges for enhancing data rate, reducing latency, improving connectivity and reducing consumption. However there is one relevant mode that has not been strongly supported by the research efforts, which is Internet access for remote areas. As of today, we estimate 1.4 billion of unconnected people live in areas where mobile broadband coverage is not available, showing the immense impact of a network that can deliver high quality Internet access in remote areas. It is clear that a sustainable rural service will not be available unless network deployments and business strategies are specifically tailored to this scenario. Integrating state-of-the-art in mobile communication with business concepts of sharing economy would allow any local entrepreneur to become a profitable mobile rural infrastructure operator with extremely capillary commercialization and operating capabilities. The goal of 5G-RANGE is surpass the limitations of current technologies, making the coverage of low populate areas a feasible business. We aim for a cell radius above 50 km with at least 100 Mbps at the edge, employing both licensed and unlicensed frequencies, while cognitive radio techniques will be used to protect incumbents. Clearly, this new 5G mode needs to be flexible to comply with different applications and services. The current standards cannot use spectral wholes and have limited spectrum mobility. A new waveform needs to be considered and the mechanisms in the MAC and Network layers must take advantage of the features of this waveform in order to provide the desirable dynamic and fragmented spectrum allocation. The combination of an innovative PHY and a cognitive MAC will result in a 5G mode able to reach the unconnected people, not only in Brazil, but worldwide. This network will also trigger new agribusiness services, bringing new revenues for different sectors of our society.

Keywords: internet access,remote areas,cognitive radio,large coverage,agribusiness applications,high mobility,digital dividend,tv white spaces
DEVELOPMENT AND MARKET UPTAKE OF INNOVATIVE SYSTEM TO OBTAIN ELECTRICAL ENERGY FROM OCEAN WAVE RESOURCES (BUTTERFLY)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Cross-cutting marine and maritime research
Action type: SME instrument
Countries involved: Spain
Call: Supporting SMEs efforts for the development - deployment and market replication of innovative solutions for blue growth (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-04-01
End date: 2017-09-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The general objective of BUTTERFLY project will be focused on the development, demonstration and further commercialization of an efficient system that harvest the ocean energy from waves to produce cost-competitive and sustainable electricity. BUTTERFLY solution, is a Wave-To-Wire (W2W) system that aims to produce blue energy to be integrated with other renewables and traditional electrical supply of coastal regions. This innovative solution is composed of a Wave Energy Converters (WEC) that captures the energy from waves, and a Power Take-Off (PTO) system that converts the energy into electricity. The innovative character of BUTTTERFLY will maximise the capture and conversion efficiencies, providing affordable blue energy to coastal areas with good wave resources. This potential market includes coastal regions and big islands connected to the grid, but also small islands and remote coastal communities that are fully dependent on diesel generators for most of their energy requirements, being exposed to diesel fuel price volatility, frequent fuel spills and high operation and maintenance costs. This system will have the following features: - Lower investment per KW installed power than other ocean devices - Lower cost per kWh obtained than the other energy sources. - Sustainable energy production - No electricity generation in the sea - Continued and predictable energy supply - Easy to build, install and maintain - Customizable system for different type and size of waves - Achieve good levels of power quality - Wide replicability for islands and coastal regions - Contribution to the reduction of carbon footprint and emissions

Keywords: wave energy,wave energy converter,power take off,renewable energies,marine energy,ocean energy,blue energy,sustainable electricity,islands,coastal areas
The first hybrid simulation platform for neurosurgery (UpSurgeOn Academy)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-10-01
End date: 2021-12-31
Duration (months): 27.0
Total project cost (EUR): 1726080.0
EU funding (EUR): 1208256.0
Participants: 1
Project status: CLOSED

Neurosurgery training is one of the most long-lasting and expensive of all medical disciplines. Learning programs average 15 years and tuition fees can reach up to €60,000 per year. Even in the countries where public education reigns, hospitals need to bear a high cost per resident which can go up to €1 million. For this reason, there is a shortfall of 23,000 neurosurgeons in low and middle-income countries, and 5 million unattended neurosurgical cases that go unmet each year worldwide. Furthermore, cases of malpractice in neurosurgery are on the rise (by 25% since the 90s): 3.4% neurosurgeons face malpractice claims every year, and 19% any type of claim, rising the indemnity payment up to €278,000 per physician. UpSurgeOn Academy aims at answering to these problems as it is the first hybrid simulation platform which integrates digital and physical tools for neurosurgery training. It includes a complete toolkit of Apps for letting neurosurgery students study all types of procedures, benefits from the closest-to-reality existent experience with a physical device replicating an actual human brain in size, precision and texture (the Brainbox) and then practise through the use of Augmented Reality (AR). Its low price makes it utterly affordable for its identified and verified key target customer: medical students, neurosurgery residents and advanced surgeons, thus i) enabling neurosurgery students to enhance their academic curriculum before they become residents; ii) bringing reliable simulation to neurosurgery, as it is one of the areas of medicine which need most; iii) reducing the number of malpractice cases by introducing better resources in neurosurgery education programs that boost professionals’ skills; iv) increasing the number of neurosurgeons, especially in low and middle-income countries. With this project, our company aims to acheive €15,4M in revenues, with a cumulated EBITDA of €5.2M, and a ROI of 3.3 in the 5 years following the completion of Phase 2.

Keywords: practical surgical training,neurosurgery applied training,quality and apeal of neursurgical training programs,neurosurgery malpractice
The world’s first Terahertz application for Inspection-As-A-Service: Ensure quality and reduce waste in industrial production through inline inspection (TULIPZ)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2019)
Start date: 2020-04-01
End date: 2022-07-31
Duration (months): 28.0
Total project cost (EUR): 3372500.0
EU funding (EUR): 2360750.0
Participants: 1
Project status: CLOSED

Surprisingly, many high-added value and high-quality performance-driven industries such as automotive, aerospace, robotics, medical, and technical textiles rely on old-fashioned and manual inspection methods. Defects and contaminants are often detected only after production (end-of-line quality control) using cumbersome, slow and expensive X-Ray machines. This problem has a major impact on manufacturers and consumers as raw materials, production efforts and energy are irreversibly wasted due to this late and partial inspection. Moreover, due to the emergence and increasing prominence of high-performance composites cut across all fields – wind power (e.g. wind turbine blades), aerospace, automotive - effective and reliable production control and inspection techniques still remain incipient – most of the inspection techniques are still done in a visual and manual way (“market creation” opportunity). Tulipz is a disruptive IoT plug & play solution for inline production and quality control, which combines a patented Terahertz (THz) technology with proprietary deep-learning algorithms deployed as a software-as-a-service (SaaS) platform. It allows for total real-time, distributed, non-destructive inspection (NDI) along production lines instead of the currently used end-of-line approach, thus guaranteeing quality, increased throughput and minimal waste. The estimated benefits to customers are substantial: a 5x increase in productivity, equipment uptime of 99.99% and a reduction in production waste by 5%. TiHive is a team of energetic, enthusiastic and disruptive entrepreneurs, industrialists and researchers who founded the company after ten years of advanced R&D. Our ambition is to become world leader in distributed inspection for high quality, performance engineered products, in particular technical textiles by 2025. This will reinforce the world leadership of Europe in technical textiles.

Keywords: advanced materials,composites,technical textiles,factories of the future,internet of things,terahertz,industry4 0,cmos,nano electronics,semiconductors,testing and inspection
Quantification of the participation of soils in the microplastic pollution cycle and evidence based model analysis of atmosphere to ocean soil microplastic interaction (PlastiSol)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: New Zealand,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 290084.16
EU funding (EUR): 290084.16
Participants: 2
Project status: TERMINATED

There is little doubt that micro and nanoplastics (MnP) are in our soils across the globe. Numerous studies including my own have found that atmospheric deposition alone is enough to pollute even our most pristine remote areas. What is unknown is what happens to it once it is there. Is it transported by runoff or pushed deeper into the soil? What is the effect of the chemicals leached from MnP on soil microbiome, air and receiving river ecosystems? Many of these (e.g. flame retardants) are ‘forever chemicals’, never break down but continue to cycle in the food chain. What is the threshold before irreversible damage occurs, and have we pass it? These knowledge gaps have far reaching implications for food and water security and survival of the fragile ecosystems that make our planet habitable. PlastiSol seeks to address these urgent questions in an attempt to push the boundaries of our knowledge on this emerging threat. Through studying a cross section of land use soils MnP and associated leachates and the processes that contain or transport these pollutants, this project will advance MnP pollution science beyond considering soil as a sink, evidencing atmospheric and receiving waterway impacts of soil pollution. Furthermore, examining the internal mechanisms of soil MnP movement and leachate release will define the potential groundwater influence, land management activities and storage capacities of different land use soils’ MnP. With this evidenced process knowledge, the impact of soil MnP on the global MnP cycle will be established, enabling soil to be included as a source, transport pathway and sink of plastic pollution, advancing the accuracy of global MnP quantification and the impact of soil MnP on ecosystems and all environmental compartments. Only in understanding the extent and impact of soil plastic pollution can it be effectively managed through change in land use practices and policy advancements.

Keywords: atmospheric modelling,river and catchment modelling,sediment plastic transport,catchment pollution,soil transport modelling,land use impact assessment
Smart Water Futures: designing the next generation of urban drinking water systems (Water-Futures)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Germany,Cyprus,Greece,Netherlands,United Kingdom
Call: ERC Synergy Grant (ERC-2020-SyG, 2020)
Start date: 2021-08-01
End date: 2027-07-31
Duration (months): 72.0
Total project cost (EUR): 9982320.0
EU funding (EUR): 9982320.0
Participants: 5
Project status: SIGNED

The world population living in urban settlements is expected to increase to 70% of 9.7 billion by 2050. Historically, as cities grew, new water infrastructures followed as needed. However, these developments had less to do with real planning than with reacting to crisis situations and urgent needs, due to the inability of urban water planners to consider long-term, deeply uncertain and ambiguous factors affecting urban development and water demand. These, coupled with increasingly uncertain climate conditions, indicate the need for a more holistic and intelligent decision-making framework for managing water infrastructures in the cities of the future. This project aims to develop a new theoretical framework for the allocation and development decisions on drinking water infrastructure systems, so that they are socially equitable, economically efficient and environmentally resilient, as advocated by the UN Agenda 2030, Sustainable Development Goals. The framework will integrate real-time monitoring and control with long-term robustness and flexibility-based pathway methods, and incorporate economic, social, ethical and environmental considerations for sustainable transitioning of urban water systems under deep uncertainty with multiple possible futures. The Water-Futures team will build on synergies from the four research groups, transcending methodologies from water science, systems and control theory, economics and decision science, and machine learning, into an integrated decision and control framework, to be implemented as an open-source research toolbox. The new science outcomes will be applied to three case studies exemplifying different types of urban water systems: a mature, relatively stable system; a mature and rapidly expanding system; and a relatively recent supply system in a developing country with high growth and special challenges, including limited resources, intermittent supply and high water losses.

Keywords: urban drinking water systems,computational intelligence,hydroinformatics,cyber physical systems
Vibronic control of organic electronic devices (VIBCONTROL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: United Kingdom,United Kingdom
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-06-01
End date: 2021-05-31
Duration (months): 72.0
Total project cost (EUR): 1497257.0
EU funding (EUR): 1490967.21
Participants: 2
Project status: CLOSED

Organic electronics (OE) is an expanding research field that exploits the electronic functionalities of organic molecules to make them robust and cost-efficient building blocks for future electronic devices. Due to the ‘soft’ character of organic materials, their electronic properties are defined by vibronic coupling (VC) phenomena which are a result of the interaction between electron and nuclear dynamics of the molecule. This research program aims to unlock a new direction of experimental studies investigating and exploiting VC in OE devices by using optical control of nuclear motion. The growing awareness that VC underlies diverse phenomena from physics to biology stimulates a broad interdisciplinary effort to address this issue. However, in the field of OE, the lack of synergy between device and optical studies holds the potential functionality offered by VC effects from being attained. In 2012, I proposed a direct route to control the performance of OE devices by optically switching the vibronic states of the molecules. Though this work came specifically in connection with organic photovoltaics, it provides the starting point for a more fundamental and broad reaching of VC phenomena. The proposed research program will use this opportunity. I will apply state-of-the-art developments in infrared light shaping to create a well-defined coherent superposition of molecular vibrational motions inside devices and study their influence on electron dynamics with device-specific spectroscopic techniques. This approach combines recent advances in ultrafast spectroscopy and OE to extend our fundamental understanding of molecular charge transport. Our methodology will become a tool for elucidating current pathways in organic nanodevices and offer access to non-equilibrium phenomena down to the level of molecular junctions. This research will lead to the development of new design rules for OE materials serving future advances in molecular electronics, computing and sensing.

Keywords: ultrafast spectroscopy,molecular junctions,bio electronics,ir spectoscopy,organic photovoltaics,charge transport,vibronic coupling
Ground breaking 3D cell culture platform to eliminate animal testing in pharmaceuticals (DifMATRIX)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Czechia
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-03-01
End date: 2018-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The use of in-vitro testing (in simulated environment) is the future of drug development, cancer research and medical research in general since it overcomes the practical and ethical issues associated with human and animal experimentation. However, as much as 85% of early clinical trials currently fail despite successful preclinical in-vitro testing; in the case of clinical cancer trials it is less than 8%. The main reason for such low success rates is that currently used 2D cells do not behave the same in living bodies as in cultures. As a consequence, animal testing continues to be widespread despite the associated cost and strong ethical concerns it raises. This is also extremely costly in time and resources which raise consumer prices for life-saving medications. InoCure is addressing this problem with the DifMATRIX - a unique 3D scaffolding platform with drug delivery embedded system, for cell culture used in molecular biology and tissue engineering. DifMATRIX enables to simulate natural cell phenotype (in vivo) in the in-vitro environment. It redefines in-vitro preclinical testing standards, significantly improving preclinical-to-clinical translation efficiency and provide an alternative to animal testing models. The predicted impact of the project is to eliminate the animal testing phase from the drug development process. The project is well aligned with new trends in cell and tissue culture supplier market. Globally, this market is witnessing significant growth due to increasing demand for biopharmaceuticals and increasing R&D in this field. The global cell/tissue engineering supplies market is expected to reach $28 billion in 2020. The market demand for DifMATRIX has been confirmed by customers currently using our passive InoMATRIX product, and by the letters of intent from prospective customers. Following the proposed Phase 1, Inocure target is to apply for the Phase 2 project to scale-up the production and launch commercialisation of DifMATRIX.

Keywords: medical breakthrough,no animal testing,clinical research,disruptive innovation for medicine
NEW METHOD TO ACTIVATE STREPTOMYCES SECONDARY METABOLISM CRYPTIC PATHWAYS (StrepCryptPath)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Spain
Call: ERC Proof of Concept Grant (ERC-2018-PoC, 2018)
Start date: 2019-06-01
End date: 2021-04-30
Duration (months): 23.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The aim of the StrepCrypPath is to test the industrial potential of a new approach to enhance Streptomyces secondary metabolism, discovered in our ERC-StG Strp-differentiation (280304) project. We discovered a pleiotropic regulator of differentiation and secondary metabolism in the S. coelicolor model strain. The S. coelicolor strain lacking this regulator is the first Streptomyces reported to produce secondary metabolites during its whole developmental cycle, including germination, the exponential growth phase and the stationary stage. S. coelicolor encodes 30 secondary metabolites, but only two are produced in high amounts under the culture conditions used in our lab. The expression of 15 secondary metabolite clusters (50% of the total), including 6 predicted to participate in secondary metabolite biosynthesis never observed in the lab (cryptic pathways), is activated/enhanced, in our mutant. The gene encoding this new regulator is highly conserved in Streptomyces. We will explore if the inactivation of the orthologues of this regulatory gene in industrial streptomycetes causes the same phenotype observed in S. coelicolor: secondary metabolism and cryptic pathway activation. We will create integrative conjugative plasmids harbouring antisense mRNAs to inactivate this gene. We do not expect that this method will enhance and/or activate all secondary metabolite clusters. However, if as it happens in S. coelicolor, we can activate/enhance 50% of the secondary metabolite pathways, including several cryptic pathways, in any streptomycete, we can revolutionise the screening for new secondary metabolites from streptomycetes.

Keywords: streptomycetes,antimicrobials,antibiotics,secondary metabolites,microbial resistance,screening,pharma