Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
reduce - recycle - reuse eMobility - retrofitting-kits for busses (EU-elabus4.0)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Germany,Poland,Netherlands
Call: Small business innovation research for Transport (H2020-SMEINST-1-2014, 2014)
Start date: 2015-06-01
End date: 2015-08-31
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 3
Project status: CLOSED

The overall objective of the envisaged project is to establish a production system for refurbishing and retrofitting the bodies of diesel-driven-busses after their service life. These bodies are usually still in a very good condition and have a high potential for being refurbished and retrofitted with electric powered drive systems. In Germany the public transport sector is about 39.600 busses strong (2013). Only 46,6% of these buses have EURO-IV and higher, 20,4% EURI-III, 23,5% EURO-II and 9,5% are much older. European wide (EU27) there are about 8.200.000 busses and coaches ! Like in Germany (39.600 of 79.200) around 50% of this are busses in public transport – around 400.000 busses. This shows the high potential of this market in whole Europe like this map is also showing. Retrofitting is not only a sustainable way to use resources , but it is also economic feasible for the customer, because the body and many of the components are reused and have a remaining value about 100 – 200 T€! Furthermore, the ecologic impact plays a more and more important role. First cities decided to close their inner cities up to 2020 for diesel-vehicles (for example Paris ) or for vehicles with CO2-emissions (for example London) or Copenhagen as carbonneutral city up to 2025 . We can be sure, that other regions and cities will follow. E-mobility is the key to success and needs further funding for development. The objective of this project is to demonstrate, that rebuilding busses with electric powered drive systems will have a significant market in Europe and a large and sustainable benefit for the public transport sector: • economic wise, because the operational costs are about 50% cheaper than diesel-driven busses (assembly, operation, maintenance) • innovation wise, because these vehicles are equipped with several sensors that are contected to the internet to give more precise information • ecological wise, because of CO2-emission-free operation.

Keywords: emobility,electricla busses,public transport,retrofit kit
Active Organ Phantoms for Medical Robotics (ACTIVEPHANTOM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-03-01
End date: 2018-08-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Robot-assisted and minimally invasive medical procedures are impacting medical care by increasing accuracy, reducing cost, and minimizing patient discomfort and recovery times after interventions. Developers of commercial robotic surgical systems and medical device manufacturers look for realistic phantoms that can be used in place of animal experiments or cadavers to test procedures and to train medical personnel. Existing phantoms are either made from hard materials, or they lack anatomical detail, and they are mainly passive and thus unrealistic. Here, we use recently developed fabrication know-how and expertise within our ERC-funded research to develop the first active artificial urinary tract model that includes a kidney, a bladder, and a prostate. Rapid prototyping is combined with a fabrication step that we have developed to permit the incorporation of active elements, such as a peristaltic system and fluidic valves in the phantom. We have developed smart material composites that reproduce the mechanical and haptic properties, and that give ultrasound contrast indistinguishable from real organs, while permitting anatomical details to be reproduced with a mean error of as little as 500 microns. Feedback from a major medical device company indicates that ours is a unique phantom with unprecedented accuracy for which there is a market. Within this POC grant we want to develop a complete prototype, and to demonstrate a series of medical interventions on the phantom, including endoscopic diagnostic procedures (cystoscopy and ureterorenoscopy) and endoscopic treatment procedures (laser lithotripsy). The grant will allow us to protect our know-how, identify further markets, and develop a commercialization strategy. Overall, this project will generate the first active phantom system that permits the testing of surgical instruments and procedures, with a sizeable market potential.

Keywords: phantom,model,3d fabrication,3d printing,organ,medical device,training,teaching
A hydraulic collection tower, with a novel energy storage device for wave energy arrays (OHT)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Sweden
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-06-01
End date: 2017-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Wave energy convertors (WEC) capture the energy contained in ocean waves and use it to generate electricity. The use of wave energy provides the opportunity to generate energy at a wide range of locations throughout Europe, which will strengthen the stability of Europe’s energy networks. WEC developers have still not achieved a lower cost of energy through a viable and competitive technology. Ocean Harvesting Technologies AB (OHT) was founded in 2007 and develops an innovative and patented hydraulic collection system and storage technology for wave energy arrays. The power captured by wave energy converters (WEC) is pumped in the form of pressurized fluid through a piping system to a central tower, where the collected power is first smoothed by the novel OH energy storage device and then converted into electricity. OHTs vision is that their technology will solve the problems with current centralized hydraulic collection systems through a more efficient solution and ultimately lead to lower cost of energy. Besides generating efficient and even power, the simplicity of the OH design will allow better protection in rough conditions, and make its manufacture impressively cost-efficient. OHTs energy storage technology will not only remove the intermittent nature of wave energy but turn wave farms into flexible power plants. OHT have raised 3,2 M EUR in private equity to date.

Keywords: wave energy,energy,green energy,energy storage,renewable energy
Spin-resolved strong field ionisation (SSFI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: SIGNED

Molecular movies depicting chemical reactions via attosecond (10^-18 s) snapshots, which vastly improve our understanding of molecular dynamics is within our grasp. Strong-field imaging techniques under development, such as photoelectron holography, promise just this. However, up until very recently all strong-field theoretical models have neglected spin and spin-orbit coupling. Initial work including spin in the initial state, along with recent experiments, has shown that spin in strong-field processes is vitally important, leading to different ionisation probabilities which in turn may alter the all important electron dynamics. In this project, I will utilise and develop cutting edge theoretical frameworks to fully include electron spin for strong-field processes in atoms and molecules. I will develop a semi-analytic model, which fully includes spin and spin-orbit coupling for single active electron and two active electron cases. This is motivated by the long history of semi-analytic methods that have been developed in this field, which have enabled unprecedented access into the electron dynamics for strong-field processes. As such, developing a model for spin will reveal deep new physical insight. I will validate the methodology by exploiting my supervisors expertise and contacts, collaborating with theorists employing complementary cutting-edge numerical models and with the only group of experimentalists to have performed spin measurements on strong-field processes. A proper treatment will allow more advanced and robust imaging techniques. I will explore the use of spin to enhance existing imaging processes such as photoelectron holography. Furthermore, I will develop the semi-analytic model for two electrons and explore spin entanglement and correlation with momentum in two-electron ionisation processes, to design entirely new imaging procedures. This analysis will also open up the possibility of exploiting this system for quantum information purposes.

Keywords: strong field physics,spin,electron holography,non sequential double ionisation
Nervous system reprogramming by flexible neuropeptidergic networks (FLEXPEPNET)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-01-01
End date: 2025-12-31
Duration (months): 60.0
Total project cost (EUR): 1559807.5
EU funding (EUR): 1559807.5
Participants: 1
Project status: SIGNED

Animal brains are wired according to a series of remarkable genetic programs that have evolved over millions of years. Much of our behavior, however, is the product of experiences that happen to us on much shorter time scales. The ability of the nervous system to properly respond to aversive stimuli is crucial for animal well-being and survival. In many vertebrate sensory systems, persistent stimuli are coded by tonically active neural circuits. As opposed to phasic sensors that adapt rapidly, tonic neurons reliably convey stimulus intensity over long time periods and are essential for cues that need to hold attention, e.g. harmful stimuli. How persistent aversive stimuli are molecularly encoded and reprogram behavior remains elusive. Our working hypothesis is that aversive challenge recruits a network of neuropeptide signaling pathways that is sculpted by experience and mediates diverse acute and long-lasting behavioral responses. We will test this hypothesis on the small and well-described oxygen-sensing circuit of C. elegans. Because neuropeptidergic networks are notoriously complex, such a highly controlled context for pioneering research on their involvement in tonic aversive signaling is preferable. First, my team will develop tools for the in vivo reporting of neuropeptide GPCR activation, establishing SPARK in a living animal, which will allow conceptual advancements with unprecedented detail. Pertinent questions we will then address include: ‘How do cellular networks respond to changes in neuropeptidergic network activities in an aversive signaling context?’; ‘What are behavioral implications of neuropeptidergic network activity upon aversive challenge?'; and ‘Do neuropeptidergic networks contribute to cross-modality?' We expect that on the long term, this project will impact our understanding of how tonic peptidergic circuits influence and organize habituation, learning, forgetting and modus operandi of nervous systems in general.

Keywords: neuropeptide,g protein coupled receptor,tonic neural signaling,experience dependent plasticity,caenorhabditis elegans
Women at the Cutting Edge. Assessing the gendered impact of industrial logging on well-being in Solomon Islands. (WACE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Indonesia,Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-06-01
End date: 2021-07-05
Duration (months): 30.0
Total project cost (EUR): 197725.5
EU funding (EUR): 197725.5
Participants: 2
Project status: CLOSED

Women are often negatively affected by industrial logging in tropical forests. They are excluded from decision-making, and are vulnerable to the sexual exploitation, alcoholism and conflict associated with this extractive industry. However, the scientific literature on the impacts of logging on women’s well-being is fragmented, and the subject receives little attention from policy and industry. This project aims to address this gap by: 1) publishing 3 peer-reviewed articles in high-impact, open-access journals on the gendered impacts of logging in Solomon Islands, based on an innovative combination of ethnographic and quantitative research methods; 2) compiling case studies on women in logging concessions in a special issue of the journal of the European Tropical Forest Research Network; 3) developing a methodological toolkit for the systematic assessment of women’s well-being in forest concessions. The project results will be further communicated to professional and lay-audiences through oral presentations, policy briefs, newsletters, a website and on-line articles. This research and training project will consist of an 18-month secondment period at the CGIAR-Center for International Forestry Research (CIFOR, Indonesia), and a 12-month return phase at the Institute for Cultural Anthropology and Development Sociology of Leiden University (CAOS-LU, The Netherlands). As part of the Global Fellowship the applicant will undergo thorough training in the field of gender analysis in forest management through the CGIAR Gender Research and Integrated Training Sessions at the PennState College of Agricultural Sciences. She will further acquire science communication skills through CIFORs outreach office. These training components, combined with the experience of mobility and the scientific and non-scientific outputs generated by the project, will prepare the applicant for her five-year career goal, which is to become associate professor at her home institution (CAOS-LU).

Keywords: gender,well being,industrial logging,sustainable forest management,pacific
A comparative clinical study of a stool-based versus a blood-based screening test for early detection of CRC (Monomark)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Belgium
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-04-01
End date: 2018-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer deaths in Europe and USA. Its incidence and difficult early-diagnosis make CRC a primary focus in the oncology community. Although colonoscopy is currently the most reliable clinical tool for precise detection of CRC, the invasive nature and the incurred cost have hampered the wide application of this procedure. On the other hand, the fecal occult blood test (FOBT) and the fecal immunoistochemical test (FIT) are non-invasive screening tests that can be used prior to colonoscopy. However, they both lack the sensitivity or specificity required for an effective screening tool and they require meticulous dietary restriction, overall not reaching the full compliance of the general population. Thus, there is a pressing need to identify specific non-invasive biomarkers for early diagnosis of CRC. Within the frame of the ERC starting grant OxyMO, we investigated the diagnostic potential of blood derived circulating monocytes for colorectal cancer (CRC). Our transcriptome characterization revealed a CRC-specific gene signature that was further developed as the ‘Monomark‘ diagnostic test (patent WO2013/110817), which showed a strong diagnostic power for CRC detection. This signature was triggered by signals specifically released by CRC cells regardless of their stromal niche (primary tumor vs. metastatic site) or oxygen tension. In this prospective study, we will compare the strength of the Monomark signature towards the FIT test in patients with a positive stool test. Therefore, in parallel to the routine FIT screening, blood samples will be harvested and the monocyte genetic profile will be determined. This fundamental study, will disclose the diagnostic power of our biomarker panel head to head with the well-established FIT diagnostic test, a core prerequisite for the commercialization of the Monomark test as an alternative and more reliable CRC screening tool.

Keywords: monocytes,colorectal cancer,biomarkers
European Joint Doctorate Programme on Optical Sensing using Advanced Photo-Induced Effects (OPTAPHI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Joint Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Austria,Italy,Ireland,France
Call: Innovative Training Networks (H2020-MSCA-ITN-2019, 2019)
Start date: 2020-01-01
End date: 2024-09-30
Duration (months): 57.0
Total project cost (EUR): 3761763.84
EU funding (EUR): 3761763.84
Participants: 7
Project status: SIGNED

Photonics is a key technology of the 21st century and has been identified by the European Investment Bank as being one of “the building blocks of the next digital revolution”. Photonics, with an expected world market of €615B by 2020, underpins all aspects of modern society, including optical telecommunications, biophotonics, medical technology devices and materials processing. Sensing is the largest application sector within European photonics; the compact, portable non-invasive potential of optical sensors makes them ideal solutions for industrial process analysis, environmental monitoring and food analysis. The strong industrial activity in Europe supports the employment of large numbers of highly qualified personnel, and with intense competition from China, USA and others, the demand for suitably qualified graduates has never been higher. Optical sensing is intrinsically a multi-disciplinary topic, requiring expertise in chemistry, physics and engineering; it is therefore ideally suited to a European Joint Doctorate programme. The OPTAPHI consortium brings together 5 world-leading research groups and 11 partner organisations to offer a cohort of 14 ESRs a unique opportunity; a PhD programme with cross-disciplinary training in both integrated photonics and advanced spectroscopy techniques, a double degree awarded by two of Europe's leading institutions and co-supervision by experts in each of the complementary fields. The network will focus on the cutting-edge technologies of Quartz Enhanced Photo-Acoustic Spectroscopy (QEPAS) and Photo-Thermal Spectroscopy (PTS) and includes an exciting programme of workshops, summer school and conference. OPTAPHI will demonstrate compact sensors that can be used in unmanned aerial vehicles for environment sensing, as low cost sensors for food monitoring and in industrial Process Analytical Technology, and produce new state of the art quantum cascade lasers and hybrid photonic crystal lasers customised for QEPAS and PTS.

Keywords: photo acoustic spectroscopy,photo thermal spectroscopy,photonic crystal lasers,quantum cascade lasers,gas sensing,liquid sensing
Systemic Induced Root Exudation of Metabolites: A Multimodal Approach to Uncover Root Signaling Mechanisms and the Chemical Language used by Plants to Shape the Rhizosphere Microbiome (SIREM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Israel
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2020-05-01
End date: 2025-04-30
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The prosperity of plants and human beings is dependent on the outer layer of soil that makes up our planet’s shell. Curiously, a significant portion of plants' most precious elements, carbon and nitrogen, is secreted by roots into soil in the form of chemically-rich exudates. This is not merely 'dumping' of waste but rather the chemical language of plants, used in their underground communication with billions of detrimental and beneficial microorganisms. Yet, an important question remains to date: How do plants control and manipulate root metabolism and exudation in time and space to fine-tune this complex underground web of interactions to their benefit? The proposed project takes on this challenging question and aims to decipher the newly discovered process we term 'SIREM', for 'Systemic Induced Root Exudation of Metabolites'. SIREM is a fundamental feature of rhizosphere interactions, in which biotic stimuli occur locally and exudation in systemic parts of the root ‘conditions’ the rhizosphere environment to maintain plant fitness. SIREM objectives include: (i) dissecting the SIREM signaling pathways, focusing primarily on the mobile signal(s) and receiving proteins at the systemic root; (ii) discovery of the exudation machinery and its genetic control; and (iii) establishing the role of SIREM signaling and exudation-metabolites in shaping the rhizosphere microbiome. The unconventional integration of approaches in SIREM underscores the unique combination of our team's expertise in plant metabolism, computational biology, microbiome exploration and the application of cutting-edge analytical and molecular technologies for high-resolution spatial-temporal profiling. Outcomes of the project will have wide-ranging impacts on understanding systemic signaling and metabolic and transport systems in plants and are anticipated to drive the new biotechnological concept of 'Exudation Agriculture'.

Keywords: metabolomics,secondary metabolites,plant metabolism,root exudates,systemic response