Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Detection of NGT products to promote innovation in Europe (DETECTIVE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Sweden,Cyprus,Belgium,Austria,Germany,Slovenia,Poland,Netherlands,Switzerland,China
Call: New detection methods on products derived from new genomic techniques for traceability, transparency and innovation in the food system (HORIZON-CL6-2023-FARM2FORK-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 6026428.75
EU funding (EUR): 6026428.75
Participants: 20
Project status: SIGNED

DETECTIVE will develop and validate approaches to detect, identify, and quantify plant and animal products resulting from new genomic techniques (NGTs). NGT products are currently regulated as genetically modified organisms (GMOs) in the EU. This means that they are subject to authorisation procedures, which include event-specific methods for detection, identification, and quantification of the corresponding food and feed products. However, the analytical methods commonly used for transgenic GMOs are often not suitable for NGT products as these often do not contain genetic elements that allow unambiguous traceability. DETECTIVE will investigate the technical forefront for detection including the latest PCR-based and sequencing approaches for NGT products with known and unknown genetic alterations, and validate these in national enforcement laboratories. We will build a cluster of databases to enable Machine Learning-based screening. While technical detection may be limited, DETECTIVE will also look into non-technical approaches to traceability and authenticity to develop comprehensive solutions, including their respective economic and legal implications, to a wide range of NGT products. By taking a systemic and holistic approach, DETECTIVE will identify the boundary conditions that traceability approaches need to meet. The results will promote NGT research and innovation (R&I) that enable a resilient primary production (agriculture and animal husbandry) of highly nutritional food products and thereby contribute to a sustainable, healthy and inclusive food system in Europe that enables choice for both producers and consumers. DETECTIVE is a multi-disciplinary and multi-sectoral consortium and its links to relevant stakeholders through a Stakeholder Advisory Board will enable an improved understanding and awareness of the challenges related to traceability, authenticity and transparency of NGT-derived products.

Keywords: new genomic techniques,gene editing,detection,traceability,authenticity,transparency
Transnational Fatherhood, Negotiating Masculinity and Parental Care in the Digital Communication Era (TFNMPC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-15
End date: 2026-09-14
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 1
Project status: SIGNED

The research proposal aims at investigating the relationship between transnational fatherhood, negotiation of masculinity, and parental care practices among Pakistani migrant men in Italy. The migration patterns prompted by socioeconomic factors, traditional gender roles, and improved quality of life in certain regions have led to a surge in migration predominantly by men. This study seeks to explore how transnational fathers navigate their roles across family, work, and society and use digital communication tools to maintain family connection. Guided by an intersectional perspective and innovative methodologies, this research project focuses on the experiences of Pakistani migrant men. The research objectives include investigating the impact of transnational fatherhood on the construction and negotiation of masculinity, exploring the role negotiation of migrant fathers, understanding the interplay between migration, masculinity, emotions, and transnational fatherhood, and analyzing how digital communication technologies influence fatherhood and care practices. By focusing on Pakistani migrant men, this research addresses a critical gap in the literature surrounding masculinity, fatherhood, and emotional care. In light of the statistics revealing the substantial influx of male migrants, particularly from South Asia, this project becomes pivotal for addressing this. The research design employs a variety of qualitative methodologies including in-depth interviews, focus group discussions, observations, and content analysis. The primary and secondary sample respondents consist of Pakistani migrant men with and without families in Italy, Italian natives interacting with Pakistani migrants, field experts and other stakeholders. The sampling strategy involves purposive selection and aims to achieve data saturation. This project aims to shed light on the complex dynamics of transnational fatherhood, masculinity, and parental care in the digital age.

Keywords: masculinity,parenthood,transnational fatherhood,communication and digital technology,relationship studies,gender
Assessing the impact of climate fluctuations on hibernation phenology using novel dental biomarkers (AROUSE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,Italy
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 4
Project status: TERMINATED

Many heterothermic mammals exploit multi-day torpor (i.e. hibernation) to face harsh climates. The timings and the regulations of this process are controlled and influenced by several intrinsic and extrinsic factors such as e.g. the circannual biological clock of the animal, the day-length, the spring temperature, the snow-melt date. Yet, how these animals answer(ed) global climate changes is still a matter of debate. With the AROUSE project I will examine the hibernation timing and the bone elemental metabolism of small mammals from a new unexplored perspective, by analyzing well-dated fossil and modern hibernating rodent teeth straddling the last glacial-interglacial cycle. Specifically, I will exploit the enamel incisor micro-chemistry (high-spatially resolved elements and isotopes), histomorphometry and proteomics of geographically-constrained Alpine marmots to: 1) precisely measure sex-specific hibernation length; 2) investigate metabolic changes in relation to (paleo)climate seasonal fluctuations; 3) unravel dental enamel secretion and mineralization behavior during winter torpor; 4) search for specific dental chemical biomarkers of hibernation, transferable to other disciplines. For the first time, this project will provide a robust tool for the retrospective study of hibernation events in dental specimens, allowing to deepen our knowledge about hibernation plasticity but also to possibly investigate the evolutionary trajectories of torpor in deep-time. AROUSE will also help to understand how marmots adapted to secular climate variations, possibly forecasting the effects of global warming on modern hibernating mammals.

Keywords: hibernation marmot tooth dental histology enamel elemental composition isotopes phenology
Alternative Chemicals and Materials integrating Safety, Sustainability, new Production technologies and Socio-economic aspects (Alchemissts)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Innovation actions
Countries involved: Spain,Germany,Portugal,Poland,Cyprus,France,Belgium,Greece,Italy,United Kingdom,Slovakia
Call: Development of safe and sustainable by design alternatives (IA) (HORIZON-CL4-2024-RESILIENCE-01, 2024)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 14839861.07
EU funding (EUR): 11939105.26
Participants: 29
Project status: SIGNED

The AlchemiSSts project will demonstrate the applicability of the Safe by Design (SSbD) framework aiming at developing and implementing safer and more sustainable alternatives to surfactants, plasticizers, and flame retardants that, being present in daily life products pose a high risk for the human health and the environment, thus considered substances of very high concern (SVHC). To this end, up to seven case studies, accounting with the relevant actors in the value chain are proposed in the project, and they will serve as proof of concept to test the SSbD framework against within its different 5 steps. The general objective of the project will be achieved by addressing specific goals such as the development of the alternative substances itself, the compilation of robust and reliable evidence for a Proof of Concept of the SSbD framework, the development of a certification methodology promoting the implementation of the SSbD concept in the industrial network. Another key pillar of AlchemiSSts project relies on the implementation of integrated approaches and tools to support safety, sustainability and social assessment based on interoperable FAIR data and models. In addition, robust data on sustainability indicators and information for assessing the impact of the outcomes of the project towards a suite of zero pollution targets will be delivered for each case. For all these relevant aspects, AlchemiSSts will be assisted by stakeholders to ensure social acceptance and economic of the foreseen innovative advance materials.

Keywords: sustainable,safety,validated,proof of concept,value chain
Twinning Approach for Computational MRI Technology and Innovation EXcellence in Turkey (TACTIX)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Panel: Life Sciences
Countries involved: Türkiye,Germany,Netherlands
Call: Twinning Bottom-Up (HORIZON-WIDERA-2023-ACCESS-02, 2023)
Start date: 2024-06-01
End date: 2027-05-31
Duration (months): 36.0
Total project cost (EUR): 1491029.55
EU funding (EUR): 1491029.55
Participants: 3
Project status: SIGNED

This project will uniquely combine the skills of European physicists, engineers, and clinicians to create the consortium Twinning Approach for Computational MRI Technology and Innovation EXcellence in Türkiye (TACTIX). TACTIX aims to enhance the scientific excellence and innovation capacity of Bogaziçi Universitesi (BU, Dr. E. Öztürk Işık, Türkiye) in the field of computational magnetic resonance imaging (MRI) through a collaboration with two leading European institutions; FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV (Fraunhofer, Prof. Dr. M. Günther, Germany) and the STICHTING AMSTERDAM UMC (AUMC, Prof. Dr. F. Barkhof, The Netherlands). TACTIX aims to elevate BU to the level of the other two TACTIX partners and create a long-lasting collaboration through education, mentoring, and a joint research project in line with the goals of the work programme topic Twinning Bottom-Up. TACTIX will design an MRI research and development program for MSc and PhD students and integrate it into the teaching platform of the European University NeurotechEU, of which BU is a partner. TACTIX will organize summer schools, winter workshops, and research visits for ECRs. Additionally, exchanges and mentoring will enhance the research excellence and management capacity of BU’s senior researchers and administrative staff. TACTIX will organize a joint research project on multiple sclerosis, a chronic yet incurable disease affecting over 400.000 individuals in the EU. TACTIX will implement a novel MRI method to detect more subtle blood-brain barrier (BBB) integrity changes than the current clinical MRI protocol allows. BBB MRI could serve as a biomarker for monitoring insidious episodes of progression independent of relapse activity, potentially allowing for earlier intervention to preserve cognitive function. TACTIX will widely engage stakeholders via peer-reviewed publications, conferences, a project website, social media, and podcasts for lay audiences, including MS patients.

Keywords: international cooperation in science and technology,magnetic resonance imaging,medical image processing,multiple sclerosis,blood brain barrier
Adjoint-accelerated Inference and Optimization Methods (AXIOM)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2025-12-01
End date: 2030-11-30
Duration (months): 60.0
Total project cost (EUR): 2493667.0
EU funding (EUR): 2493667.0
Participants: 1
Project status: SIGNED

The proposed research will demonstrate, with industrial examples, how scientists and engineers can efficiently combine data with prior physical knowledge. It will leverage Bayesian inference for rigour, adjoint methods for speed, and fluid dynamics for impact. Bayesian inference has been applied to fluid dynamics before but rarely using adjoint-accelerated inference and optimization methods (AXIOMs). These methods are crucial for practical applications because they dramatically accelerate data assimilation, especially when models contain thousands of parameters. This produces quantitatively-accurate physically-interpretable models that extrapolate successfully in directions in which the physics holds. Furthermore, they quantify the information content of data and rank physics-based, physics-agnostic, and combined models by calculating their relative likelihoods given the data. The proposed research will exploit AXIOMs to achieve a 10 times reduction in scan time of Flow-MRI (Magnetic Resonance Imaging) compared with state-of-the-art compressed sensing, transforming the accessibility of clinical Flow-MRI. This research will achieve a similar increase in the extractable information from experimental campaigns on gas turbine rigs, increasing reliability and reducing cost in a crucial European industry. It will also infer the rheometry of opaque fluids from a single Flow-MRI image, rigorously select the most appropriate turbulence model from data, and improve the robustness of widely-used model discovery algorithms. This project will encourage researchers to consider data in terms of information content rather than file size, enable the use of physics-based models alongside physics-agnostic models, and contribute to other areas in physical science through engagement with the UK’s Alan Turing Institute.

Keywords: medical imaging,model discovery,data assimilation,bayesian inference,adjoint methods
Adaptive Control of Soft Robots for Personalized Upper-limb Rehabilitation with Machine Learning (ACORN-PURM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-02-01
End date: 2028-01-31
Duration (months): 24.0
Total project cost (EUR): 209914.56
EU funding (EUR): 209914.56
Participants: 2
Project status: SIGNED

ACORN-PURM (AC) develops a next-generation upper-limb rehabilitation system that leverages adaptive control of soft robots and ML to provide personalized therapy based on individual patient needs, significantly improving user engagement and recovery outcomes. Stroke, spinal cord injuries, and other neurological conditions cause upper-limb disabilities, affecting millions globally and leave them with impairment. It creates a significant burden on healthcare systems. Current rehabilitation approaches often lack personalization, leading to decreased motivation and suboptimal outcomes. AC addresses this critical gap by developing an innovative solution that is: more engaging, data-driven, and patient-specific system that tailors therapy to individual needs, enhancing patient engagement and potentially accelerating recovery. The system has the following unique features: Gamified exercises enhance motivation and adherence to therapy schedules, real-time adjustments based on user intent and fatigue levels optimize therapeutic benefit, soft robotics ensure patient comfort and safety during rehabilitation sessions. Existing robot-assisted therapies are often rigid, uncomfortable, and lack real-time adjustments based on individual progress, offering one-size-fits-all approaches. Relying heavily on subjective therapist evaluations for progress tracking can be repetitive and tedious, leading to patient dropout and possess limited ability to anticipate user intentions. AC advances the field by 1) Developing Adaptive Controllers with ML that will adjust assistance levels based on individual real-time data for a truly personalized experience, 2) Utilizing DL for Advanced Movement Recognition and Assessment to analyze user data for objective assessment of subtle improvements and compensation strategies, 3) Creating gamified therapy with ML Integration to have engaging games that dynamically adjust difficulty and target specific user needs, promoting long-term engagement.

Keywords: rehabilitation,neurorehabilitation,physical medicine,physiotherapy,semg,electromyography
EBIO-HUB: CHAIR OF RESEARCH CENTRE IN BIOMEDICAL ENGINEERING (eBio-hub)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Coordination and support actions
Countries involved: Romania
Call: ERA Chairs (HORIZON-WIDERA-2022-TALENTS-01, 2022)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 2
Project status: SIGNED

The ambitious aim of the project is to establish eBio-hub- research centre in Biomedical Engineering within University „Politechnica” of Bucharest (UPB) leaded by Era Chair holder. The goal of the eBio-hub project is to unlock and foster excellent research in biomedical engineering, capitalizing the existing knowledge in UPB and integrating with local research and clinical expertise from University of Bucharest, Carol Davila University of Medicine and Pharmacy and local hospitals as well as making use of the newly created research infrastructure (INOVABIOMED) by setting up a strong research group and attracting top academics in the field, rising the competitiveness of UPB research in the European Research Area (ERA). The developing of biomedical engineering - a discipline that applies engineering principles of design and analysis to biological systems and biomedical technologies- is in line with the Romanian National Strategy for R&D. The Chair and the eBio-hub centre will address the main barriers faced in UPB such as lack of institutional organization in linking UPB research teams with different expertise and linking the existing UPB research teams with other local research institution, lack of financing, and practice not in line with open recruitment policy. By establishing a Chair Holder with excellent research credentials and leadership competences, by creating a research team with broad expertise and wide network for collaboration, will greatly improve the research culture and research performance at UPB. Sustainability will be granted by research funding procurement for projects, structured cooperation with local or international industrial and public research and educational entities, establishment of a new study field in the doctoral programs at UPB, PhD summer school and other training programs. By setting a best practice example and through a well-thought outreach campaign the project will stimulate structural changes throughout UPB.

Keywords: biomedical engineering,research center,era chair,
A Multiplexed Plasmo-Photonic Biosensing Platform For Rapid And Intelligent Sepsis Diagnosis At The Point-Of-Care (AMBROSIA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Research and Innovation actions
Partnership: Photonics (co-programmed)
Countries involved: Greece,Netherlands,Switzerland,United Kingdom,Spain,France,Ireland,Czechia
Call: Advanced multi-sensing systems (Photonics Partnership) (RIA) (HORIZON-CL4-2022-DIGITAL-EMERGING-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 3738062.66
EU funding (EUR): 3689509.66
Participants: 14
Project status: SIGNED

AMBROSIA aims to provide the foundations for a multi-sensing future-proof Point of Care Unit for sepsis diagnosis offered by a CMOS compatible toolkit and enhanced by on-chip photonic neural network technology to provide an accurate and rapid diagnosis. AMBROSIA will be investing in the established ultra-small-footprint and elevated sensitivity of integrated plasmo-photonic sensors reinforced by the well-known on-chip slow-light effect and micro-transfer printed lasers and photodiodes on Si3N4, as well as the functional processing and classification portfolio of integrated photonic neural network engines, towards painting the landscape of the next-coming disruption in sensor evolution, tailoring them in System-in-Package prototype assemblies, with the sensors being cheap disposable pluggable modules that can rapidly and accurately diagnose sepsis at the bedside in clinical environments. AMBROSIA targets to demonstrate a Point of Care Unit incorporating: i) a switchable sensor area array, with each sensor area facilitating a pluggable, 8-channel label-free plasmo-photonic sensor for sepsis diagnosis with a sensitivity over 130.000nm/RIU and a Limit of Detection below 10-8 RIU for each interferometric sensor, ii) an embedded Si3N4 photonic neural network processing and classifying at the same time the data from at least 7 biomarkers with zero-power providing in the first minutes an accurate and rapid diagnosis for sepsis, iii) Micro-transfer printed lasers and photodetectors on chip that will drastically decrease costs of both the sensing and neural network modules, and render the sensor arrays disposable.

Keywords: biosensors,plasmo photonic sensors,point of care diagnostics,sepsis diagnostics,neuromorphic photonics,active passive integration,micro transfer printing,