Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Optimization and its Applications in Learning and Industry (OPTALI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Germany,Denmark
Call:  (FP7-PEOPLE-2009-IRSES, 2009)
Start date: 2010-12-01
End date: 2015-11-30
Duration (months): 60.0
Total project cost (EUR): 383400.0
EU funding (EUR): 203400.0
Participants: 3
Project status: CLOSED

The aim of our proposal is to enhance and extend existing networks with the goal to develop and transfer optimization models and solution techniques from theory to practice. Since this step is often neglected in academic optimization theory there is the need to motivate research by real world problems in order to bridge the current gap between theory and practice. Each of the participating sites recognized that such a transfer is an important goal for the mutual benefit of researchers and practitioners. Each site has found pathways to overcome obstacles and to make optimization work in practice within their own national environment in many examples. We now want to join forces and learn from each other's expertise in order to jointly push the boundaries of optimization further towards practice in an international context. The goal will be achieved by a long-term cooperation in which we will share our knowledge about modelling, solving and implementing solutions to real-world problems within a continuing series of lectures, courses, seminars, and project works. In order to increase the impact of our cooperation we will in this proposal also focus on early-stage researchers and PhD students who will help spreading our ideas and techniques to industry and in this way contribute to a long lasting cooperation. Starting from case studies and project work which already has been done at any one of the participating sites we will identify new mathematical challenges stemming from real-world applications. This will enforce high-level research in these areas which will be carried out together with the participating PhD students on an international basis. In order to make our research results visible we will collect and publish case studies and project work and present the major results to industry in special workshops. We expect that this motivates international cooperation not only between universities but also between academics and industry.

Keywords: operations research,optimization,applications,multiple criteria,robustness,integer programming
Organisation of an e-Infrastructures Summit in sub-Saharan Africa (EI-AFRICA)

Framework: FP7 — Capacities
Programme: Research Infrastructures
Destination: Support to policy development and Programme implementation
Action type: Coordination and support actions
Countries involved: France
Call:  (FP7-INFRASTRUCTURES-2009-1, 2009)
Start date: 2009-10-01
End date: 2011-03-31
Duration (months): 18.0
Total project cost (EUR): 280680.0
EU funding (EUR): 250000.0
Participants: 1
Project status: CLOSED

The European Union and the African Union have agreed, end of 2007, on an ambitious “Joint Africa-EU partnership” paving the way for a partnership of equals based on mutual interest, fully taking into account the increased economic and social development of Africa and its move towards an integrated area. S/T cooperation on ICT can fully contribute strengthening the relations between the two continents, which has been acknowledged by the implementation of a “EU-AU Partnership for Science, Information Society, and Space”. E-Infrastructures are expected to play a key role in this cooperation, benefitting from the “EU-Africa Partnership on Infrastructure”, the AfricaConnect flagship project, the recently launched FEAST study, etc. It will soon be necessary and strategic to organise an e-Infrastructures Summit in Africa, in order that the various stakeholders involved in the development of this cooperation on e-Infrastructures can: • Exchange views and information, and identify synergies in order to increase the impact of each of their activities, • Support further policy dialogues, apprehend medium to long term perspectives and agree on an overall, coherent vision, • Develop awareness and promote the use of e-Infrastructures under development, encouraging the emergence of early adopters, of flagship projects in terms of applications, • Give the highest visibility to the European initiatives aiming at supporting the development of NRENs in Africa and their interconnection to GEANT2. The organisation of this Summit is the main objective of the 18-month eI-Africa project, proposed by an organisation having: • A long experience in the development of S/T cooperation on ICT between Europe and Africa, particularly through the coordination of the FP6 START and FP7 EuroAfrica-ICT support actions, • Successfully organised a number of forums, summits, and other major events addressing S&amp;T cooperation on ICT between Europe and other regions of the world.

Keywords: international cooperation - e-infrastructures - ict research - africa
Using aminoglycoside acetyltransferases and synthetic acyl-coenzyme A derivatives for the development of novel N-acylated antibiotics analogs (AAC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2010-01-01
End date: 2013-12-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

This proposal aims to develop a method that utilizes aminoglycoside acetyltransferases for the in-vitro generation of novel and clinically potent N-acylated aminoglicosides. I propose an efficient and unconventional chemoenzymatic approach for the production of a large variety of N-acylated aminoglycosides. By accomplishing the goals of the proposed research, I will introduce a new and important tool that will provide access to previously unknown and synthetically challenging aminoglycosides. This study may lead to the discovery of new aminoglycosides with superior activity against resistant strains as well explore directions to reduce their toxic side effects. The proposed strategy offers an elegant solution to the following problem: There are no existing general synthetic methodologies for the regio-selective N-acylation of aminoglycosides. Indeed, there are no efficient solutions as to how to chemically modify a specific amine group on an aminoglycoside that contain a series of chemically identical amines. The few existing examples require substantial efforts in both syntheses as well as in cost, and are limited to very specific cases. The three specific aims of the proposed research are: 1) To chemically synthesize coenzyme A (CoA) derivatives as substrates for the chosen AACs. Some CoAs will be utilized to directly produce the desired analogs. Other CoAs will serve as handles for the generation of libraries of new compounds after further derivatization by nucleophilic displacement or click chemistry. 2) We plan to perform biochemical studies on AACs that will target three different positions to be N-acylated on a large number of aminoglycosides. We will study enzyme promiscuity and generate libraries of new compounds using our methodology. 3) We plan to scale-up and test for antibacterial activity some of our novel analogs in search of improved antibacterial activity.

Keywords: acyl coenzyme a,aminoglycosides,aminoglycoside acetyl transferases,regio-selective n-acylation
Molecular characterization of cartilage development in the cephalopod mollusk Sepia officinalis (SEPIACARTILAGE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2009-RG, 2009)
Start date: 2009-10-01
End date: 2013-03-03
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

The presence of cellular cartilage-like tissues outside the chordate lineage is either indicative of a common origin of cartilage as a metazoan tissue type (homology), or alternatively highlights developmental and/or structural constraints in constructing an internal cellular support tissue or endoskeleton (convergence). If a genetic program for specifying chondrocytes (cartilage cells) arose only once during metazoan evolution, there should exist a molecular fingerprint that is common amongst all lineages, despite their long independent evolutionary history. The alternate hypothesis is that cartilages found within invertebrate groups are unrelated, and thus a common molecular fingerprint would not be expected. The current study is aimed at distinguishing between these two alternatives through molecular characterization of the regulation and specification of chondrocytes in the cephalopod mollusk, Sepia officinalis. The specific objectives of this study include: 1) analysis of candidate genes involved in vertebrate chondrogenesis in the context of Sepia development. 2) identification of novel genes involved in cephalopod chondrogenesis with particular focus on transcription factors. 3) functional analysis of identified genes of interest through the use of RNA interference during Sepia development. 4) characterization of the role of any novel cephalopod genes in vertebrate chondrogenesis using the zebrafish, Danio rerio.

Keywords: animal embryology,cartilage evolution,cephalopod development,molecular fingerprint,cell specification,gene expression
Carbonate Biomineralization in the Marine Environment: Paleo-climate proxies and the origin of vital effects (BIOCARB)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: ERC Advanced Grant Interdisciplinary Panel
Countries involved: Switzerland,France
Call:  (ERC-2009-AdG, 2009)
Start date: 2010-07-01
End date: 2015-06-30
Duration (months): 60.0
Total project cost (EUR): 2182000.0
EU funding (EUR): 2182000.0
Participants: 2
Project status: CLOSED

This interdisciplinary proposal has the objective to greatly enhance our understanding of fundamental biomineralization processes involved in the formation of calcium carbonates by marine organisms, such as corals, foraminifera and bivalves, in order to better understand vital effects. This is essential to the application of these carbonates as proxies for global (paleo-) environmental change. The core of the proposal is an experimental capability that I have pioneered during 2008: Dynamic stable isotopic labeling during formation of carbonate skeletons, tests, and shells, combined with NanoSIMS imaging. The NanoSIMS ion microprobe is a state-of-the-art analytical technology that allows precise elemental and isotopic imaging with a spatial resolution of ~100 nanometers. NanoSIMS imaging of the isotopic label(s) in the resulting biocarbonates and in associated cell-structures will be used to uncover cellular-level transport processes, timescales of formation of different biocarbonate components, as well as trace-elemental and isotopic fractionations. This will uncover the origin of vital effects. With this proposal, I establish a new scientific frontier and guarantee European leadership. The technical and scientific developments resulting from this work are broadly applicable and will radically change scientific ideas about marine carbonate biomineralization and compositional vital effects.

Keywords: nanosims,stable isotopes,biomineralization,cellular transport,histology,corals,foramnifera,bivalves,crinoids
A new vision on nanocatalysts (NANOSONWINGS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: ERC Advanced Grant Interdisciplinary Panel
Countries involved: Spain,France
Call:  (ERC-2009-AdG, 2009)
Start date: 2010-04-01
End date: 2015-03-31
Duration (months): 60.0
Total project cost (EUR): 3495000.0
EU funding (EUR): 3495000.0
Participants: 2
Project status: CLOSED

In recent years it has been recognized that small metal nanoparticles hold the promise that their catalytic properties may be completely different from those of their bulk analogs or their monometallic complexes. Entirely new chemical conversions may be expected because of their shape and thermodynamic properties. So far, this promise has not led to important breakthroughs, as most findings can be categorized, mostly, as typical of homogeneous catalysis, or mimics of heterogeneous catalysts, especially hydrogenation. Nanoparticles need stabilizating reagents; polymers, dendrimers, ionic liquids, detergents, solid surfaces, and small ligands, have been discovered and used by trial and error. In this project we propose the use of concave, large organic molecules that will be developed and used to stabilize small nanoparticles by covering part of the vertices and apices, thereby controlling the size and the shape, leaving edges next to the molecular wings and uncovered surface available for interactions leading to catalysis. The controlling wings contain two or three strongly binding phosphines to prevent dissociation of the controlling agent and to modify, simultaneously the electronic properties of part of the metal atoms. The organic platforms have the advantage that additional groups can be connected to them which can serve as chiral modifiers, as recognition sites for larger molecules, as additional organic catalysts, or as ligands to hold a homogeneous co-catalyst. Three high-risk reactions will be investigated, (enantio)selective hydrogenation of aromatics, conversion of glycerol to high added value products and the selective conversion of syn gas by using devices derived from homogeneous and supramolecular catalysis.

Keywords: catalysis nanocatalysts nanoparticles chemical conversion industrial applications
Spin related phenomena in mesoscopic transport (SPINMET)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Iceland,United Kingdom,Switzerland,United Kingdom
Call:  (FP7-PEOPLE-2009-IRSES, 2009)
Start date: 2010-06-01
End date: 2014-05-31
Duration (months): 48.0
Total project cost (EUR): 396000.0
EU funding (EUR): 396000.0
Participants: 4
Project status: CLOSED

The rapid progress of nanotechnology made possible the realization of nano-devices in which the motion of the carriers obeys the laws of quantum mechanics. They offer a unique laboratory for study of fundamental quantum effects, such as entanglement, topological phase and new states of matter arising from many- body correlations. Besides, mesoscopic objects can serve as components of the electronic and optoelectronic devices of new generation. In this perspective the study spin related phenomena is of particular importance as use of the spin degree of freedom opens a way to practical realization of such nanodevices as single electron memory elements, spin transistors, quantum beam splitters and spin filters. Another important topic in the field of mesoscopic transport is connected with many- body correlations, which manifest itself via variety of intriguing physical phenomena. In many of them spin plays a major role. The analysis of an interplay between spin dynamics and mesoscopic many- body correlations is thus an actual task. In a current Multidisciplinary Marie Curie FP7-PEOPLE-IRSES project SPINMET we plan to analyse many body spin related phenomena in various types of mesoscopic structures focusing on following main topics: i) Spin- interference phenomena in non-single connected mesoscopic objects ii) “0.7 anomaly” and related phenomena in 1D ballistic transport iii) New states of quantum spinor 1D liquids. iv) Spin currents and spin accumulation in real mesoscopic structures. The final objective to understand the mechanisms governing mesoscopic spin dynamics and its interplay with many-body correlations and formulation of practical recommendations for their applications in High-Tech industry: silicon spin transistor without ferromagnetic contacts; resistance standard based on the quantum spin Hall effect etc.

Keywords: spin,quantum conductance,quantum liquids,0.7 anomaly,spintronics
Towards 4D Imaging of Fundamental Processes on the Atomic and Sub-Atomic Scale (4D IMAGING)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Fundamental constituents of matter
Countries involved: Germany
Call:  (ERC-2009-AdG, 2009)
Start date: 2010-03-01
End date: 2015-02-28
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

State-of-the-art microscopy and diffraction imaging provides insight into the atomic and sub-atomic structure of matter. They permit determination of the positions of atoms in a crystal lattice or in a molecule as well as the distribution of electrons inside atoms. State-of-the-art time-resolved spectroscopy with femtosecond and attosecond resolution provides access to dynamic changes in the atomic and electronic structure of matter. Our proposal aims at combining these two frontier techniques of XXI century science to make a long-standing dream of scientist come true: the direct observation of atoms and electrons in their natural state: in motion. Shifts in the atoms positions by tens to hundreds of picometers can make chemical bonds break apart or newly form, changing the structure and/or chemical composition of matter. Electronic motion on similar scales may result in the emission of light, or the initiation of processes that lead to a change in physical or chemical properties, or biological function. These motions happen within femtoseconds and attoseconds, respectively. To make them observable, we need a 4-dimensional (4D) imaging technique capable of recording freeze-frame snapshots of microscopic systems with picometer spatial resolution and femtosecond to attosecond exposure time. The motion can then be visualized by slow-motion replay of the freeze-frame shots. The goal of this project is to develop a 4D imaging technique that will ultimately offer picometer resolution is space and attosecond resolution in time.
Nanosystems: Architectures, Design and Applications (NANOSYS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Computer science and informatics
Countries involved: Switzerland
Call:  (ERC-2009-AdG, 2009)
Start date: 2010-04-01
End date: 2015-12-31
Duration (months): 69.0
Total project cost (EUR): 2499594.0
EU funding (EUR): 2499594.0
Participants: 1
Project status: CLOSED

Nanosystems are integrated systems exploiting nanoelectronic devices. In particular, this proposal considers silicon nanowire and carbon nanotube technologies as replacement/enhancement of current silicon technologies. This proposal addresses high-risk, high-reward research, unique in its kind. The broad objective of this proposal is to study system organization, architectures and design tools which, based on a deep understanding and abstraction of the manufacturing technologies, allow us to realize nanosystems that outperform current integrated systems in terms of capabilities and performance. Thus this proposal will address modelling of technological aspects, synthesis and optimization of information processing functions from high-level specifications into the nanofabric, and new design technologies for specific aspects of nanosystems including, but not limited to, sensing and interfacing with the environment. This proposal will address also cross-cutting design goals such as ultra-low power and high-dependability design, with the overall objective of realizing nanosystems that are autonomous (w.r. to energy consumption) and autonomic (i.e., self healing). The scientific novelty of this proposal stems from the use of a nanofabric, where computation, sensing and communication are supported by a homogeneous means as well as from the study of algorithmic tools for mapping high-level functions onto the nanofabric. The intrinsic benefit of this research is to provide a design flow that extends both the technological basis and the capabilities of integrated systems, thus strengthening the industrial European position in a key sector where disruptive innovation is key for survival. The extrinsic benefit of this research is to broaden the use of nanosystems to new domains, including mobile/distributed embedded systems, health/environment management, and other areas that are critical to our lives.

Keywords: hardware,design automation,cad,synthesis,optimization,low power,reliability,integrated circuits,sensors,vlsi
Supporting the future of the NEM European Technology Platform (FUTURENEM)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Pervasive and Trustworthy network and service infrastructures
Action type: Coordination and support actions
Countries involved: France,United Kingdom,Germany,France,Germany,France,Spain,France,Germany,Spain
Call:  (FP7-ICT-2009-4, 2009)
Start date: 2009-11-01
End date: 2011-11-30
Duration (months): 25.0
Total project cost (EUR): 1293825.0
EU funding (EUR): 870443.0
Participants: 10
Project status: CLOSED

The NEM European Technology Platform is well on the way to achieving the major objectives defined at the creation of the platform, five years ago. It has helped to change the environment, encouraging the emergence of a strong European awareness of the Future Media Internet issues, supporting the creation of various forums concerned with that topic, and leading the development of a possible PPP on that subject. In that context, a new era opens now for the platform, which will have to invent its future, without losing the benefit of the work already performed. FutureNEM will assist the NEM ETP to realize that ambition. As a Support Action, it will stimulate the activities that industry cannot perform by itself. It includes the necessary tasks to meet the following objectives: •To keep a high visibility of the NEM Initiative thanks to publication of the NEMLetter and new communication tools where needed, •To promote the contribution of NEM to the various Future Internet coordination instruments in order to keep a high profile of content related matters in the Future (Media) Internet •To support the organisation of the Open NEM discussion Forum that will advise the platform on various issues •To prepare the definition of the future of the NEM Initiative, NEM2.0, •To assist the production of relevant positions on research directions and to organise the emergence of NEM public positions, •To support the organisation of the NEM Summit, •To facilitate liaison with other R&D communities around the world in order to promote the NEM messages, •To promote NEM to new communities, especially Content producers, •To develop the presence of NEM at the national/local level in order to involve more SME actors in its works. The FutureNEM consortium consists of key actors of the NEM platform and is strongly connected to the operational organization of the ETP

Keywords: nem,ppp,fia,nem summit,future internet,kic