Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Activating Circular Services in the Electric and Electronic Sector (C-SERVEES)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Enabling the transition towards a green economy and society through eco-innovation
Action type: Innovation actions
Countries involved: Spain,Italy,Germany,Spain,Spain,Italy,Italy,Austria,Spain,Spain,Norway,Belgium,Switzerland,Türkiye,Belgium,Hungary,Croatia,Romania,France,Netherlands,Portugal,United Kingdom,United Kingdom
Call: Systemic, eco-innovative approaches for the circular economy: large-scale demonstration projects (H2020-CIRC-2017TwoStage, 2017)
Start date: 2018-05-01
End date: 2022-10-31
Duration (months): 54.0
Total project cost (EUR): 7934828.19
EU funding (EUR): 6349067.37
Participants: 29
Project status: CLOSED

C-SERVEES aims to boost a resource-efficient circular economy in the electrical and electronic (E&E) sector through the development, testing, validation and transfer of new circular economic business models (CEBMs) based on systemic eco-innovative services that include: (1) eco-leasing of EEE, (2) product customization, (3) improved WEEE management, and (4) ICT services to support the other eco-services. ICT tools (relying on QR codes) will be developed as the driver of the proposed eco-innovative services to take full advantage of the potential and synergies of two major revolutions of our time: the circular economy and the Industry 4.0. The project will thus contribute to transform the E&E sector into circular and 4.0, raising new opportunities for end-users (such as their involvement in design or the access to a product as a service) and for social and solidarity economy (conducted by NGOs, like EMAUS, which employ people at risk of social exclusion to repair and prepare WEEE for re-use). The techno-economic, environmental and social viability of the new CEBMs will be validated through demonstrations dealing with four target products belonging to different EEE categories: large household appliances, IT equipment, telecommunications equipment, and consumer equipment. These EEE categories together account for 77% of WEEE collected in the EU. The project will result in an estimated economic benefit of 57.03 M€ over the period 2022-2026, which taking into account the project budget (8.03 M€) yields a ROI ~ 7.1. Specifically, the project will generate in the mid-term an economic benefit of 28.4 M€/year, with about 355 green employees (including direct and indirect jobs) and a total reduction of 2,620 tonnes CO2 eq/year. C-SERVEES (10 Member States and Turkey, including industry, end-users and researchers, ensures that strategic, design and implementation decisions) will be in line with business realities and set the foundation for realistic market-ready solutions.

Keywords: customization,electric and electronic sector,ecodesign,electrical and electronic equipment eee,waste of electrical and electronic equipment weee,ecoleasing,eco innovatives,ngos,large demos
Development of an in vitro cellular model to predict the immunological impact of dietary proteins (IVSysImmunoProt)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-01
End date: 2018-08-31
Duration (months): 24.0
Total project cost (EUR): 165598.8
EU funding (EUR): 165598.8
Participants: 1
Project status: CLOSED

As the world population continues to grow and a shortage of protein supply is foreseen, there is a need to identify new and sustainable protein sources. While these alternative proteins must be of high nutritional quality, they also need to be safe for consumption. Dietary proteins and their digestion products can influence a number of regulatory systems, including the immune system. By interacting with elements of the immune system, proteins can help balance and stabilize immune responses, but may also trigger adverse effects such as allergic reactions. While the effects of proteins and peptides on the adaptive immunity have been examined in a number of studies, few have studied how these molecules are absorbed through the small intestine and interact with the innate immune system. Since, in order to trigger an immune response proteins must first be transported across the intestinal wall and interact with the innate immune system, understanding these processes is key to determining the immunological effects of protein consumption. The aim of the proposed project is to develop an in vitro model to evaluate the impact of dietary proteins on the immune system. This research will first examine the uptake of proteins and their digests across the intestinal wall using cellular models mimicking the intestinal epithelium and subsequently investigate the effect of the absorbed proteins/peptides on the immune system’s key players, including the dendritic and T cells. The model system that this research aims to develop could help shed light on the roles played by dietary proteins in regulating intestinal immunity and serve as a tool to evaluate the immunological properties of novel and sustainable proteins. Thus, this research is of relevance not only to the European food industry, but also to public health.

Keywords: dietary protein,intestinal transport,cellular model,immunology
Advances in higher-order resummation and Parton Shower (Resummation4PS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Switzerland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 175419.6
EU funding (EUR): 175419.6
Participants: 1
Project status: CLOSED

Full exploitation of the LHC data, notably for Higgs precision measurements, traditional standard-model studies and certain BSM searches, relies on high-precision theoretical calculations. The most widely used kind of theoretical prediction is the parton-shower Monte Carlo approach (PSMC). This accounts for logarithmically enhanced contributions to all order in the coupling. While there has been much progress in the past decade in combining PSMC and fixed-order calculations, the logarithmic accuracy of the underlying parton shower has received much less attention. This project will start by developing the technology to describe the structure of the perturbative calculations at next-to-next-to-leading logarithmic (NNLL) accuracy for processes that involve QCD radiation both off the initial and the final state particles. That understanding will provide the foundations to extend for the first time the accuracy of parton showers to NNLL accuracy for a broad class of observables. Given recent developments in matching and merging of PSMCs with fixed order predictions, this will be of benefit not just for the intrinsic logarithmic accuracy of the shower but also facilitate future improvements in matching and merging, with resulting further improvements in LHC data extraction and interpretation.

Keywords: qcd resummation,jet physics,parton shower
Building resilience in the face of nexus threats: local knowledge and social practices of Brazilian youth (NEXUS-DRR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom,Brazil
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-08-05
End date: 2023-02-20
Duration (months): 36.0
Total project cost (EUR): 270327.36
EU funding (EUR): 270327.36
Participants: 2
Project status: CLOSED

The complex interactions of the food-water-energy nexus have become prominent in academic and policy discourse addressing issues of resource security, equitable access, and resource interdependencies. The nexus has gained particular importance in terms of vulnerability to natural hazards since these can negatively affect the long-term availability of resources and pose a major risk to resource security. Building long-term resilience to resource insecurity requires interconnected solutions that also take account of particularly vulnerable groups such as youth. NEXUS-DRR offers a novel and interconnected approach by linking nexus thinking with disaster risk reduction. This MSCGF investigates threats to the food-water-energy nexus from the perspective of local knowledge and social practices of Brazilian youth in marginalized communities that are affected by environmental hazards such as floods and landslides. Using participatory research methods such as citizen science, it explores young people’s everyday lived experiences and practices related to the nexus. It investigates their understanding of the nexus, their access to and their use of resources as well as their knowledge of the causes of nexus threats and future scenarios. Moreover, it explores the social practices that young people have adopted to reduce their vulnerability in terms of resource insecurity, and investigates how youth knowledge and their social practices can be valued for the development of public policies. Through joint supervision, mentoring, career and interdisciplinary skills development at the beneficiary, the University of Birmingham (UK), and the host university, the University of Sao Paulo (Brazil), this MSCGF significantly strengthens the Fellow’s profile and career opportunities as an internationally recognised researcher of excellence in applied nexus, resilience, and environmental youth research.

Keywords: food water energy nexus,disaster risk reduction,resilience,youth agency,social practices
COmplement Regulation and Variations in Opportunistic infectionS (CORVOS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Joint Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Italy,Germany,Austria,Norway,Finland,Hungary,Sweden,France,Netherlands,Denmark
Call: Innovative Training Networks (H2020-MSCA-ITN-2019, 2019)
Start date: 2019-12-01
End date: 2024-01-31
Duration (months): 50.0
Total project cost (EUR): 4088951.28
EU funding (EUR): 4088951.2800000003
Participants: 11
Project status: SIGNED

Opportunistic infections are defined as infections caused by pathogens primarily affecting immunocompromised subjects. Due to the immunodeficiency, they are difficult to treat and together the top 2 killer worldwide. Opportunistic pathogens comprise bacteria, viruses, fungi and parasites. Complement as a chief conductor of innate immunity plays a crucial role in immune defence against opportunistic pathogens. Research in this field is exploding, but also suffers from poorly coordinated intersectoral training of early stage researchers (ESRs). CORVOS, for COmplement Regulation and Variation in Opportunistic infectionS will train 15 widely recruited and highly motivated ESRs. They will fill the current scientific gap in the understanding of the role of complement in opportunistic infections, and translate this knowledge into clinical practice. ESRs will become creative alumni, all with a jointly awarded Double PhD of two European universities and equipped with entrepreneurial and clinical skills, making them attractive human resources to academia and industry alike. CORVOS is an ambitious pan-European initiative of 10 European universities, 3 biomedical companies, 2 research institutes and 3 hospitals that comprises an interdisciplinary doctoral programme including cross-sectoral secondments and training in transferrable skills. CORVOS includes 12 internationally renowned multidisciplinary scientists, 8 of them members of the European Complement Network. This established organization will ensure that the high quality and efficient implementation of the CORVOS training programme will sustain after its funding and will be embedded into existing doctoral and research training programmes across Europe. Ultimately, CORVOS doctoral and research training programme enables intersectoral research together with the transfer and exploitation of knowledge required to develop diagnostic and treatment options to save millions of lives currently lost to opportunistic infections.

Keywords: complement,lectin pathway,terminal pathway,evasion,factor h,diagnostics,monoclonal antibodies,therapy
Epithelial mRNA localization in homeostasis and pathophysiology (RNAloc)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cellular, Developmental and Regenerative Biology
Panel description: Structure and function of the cell, cell-cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Switzerland
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-02-01
End date: 2026-01-31
Duration (months): 60.0
Total project cost (EUR): 1499983.88
EU funding (EUR): 1499983.88
Participants: 1
Project status: SIGNED

Asymmetric subcellular mRNA distributions have been observed in a variety of polar cell types and organisms. RNA polarization is instrumental at the beginning of life and determines the morphogen gradients needed for embryo patterning. In highly polar neurons, subcellular transcript localization and translation are thought to enhance cellular efficiency and timely responses to extrinsic cues. However, the functional consequence of mRNA localization has, in most cases, not been elucidated. We have shown that a large fraction of an epithelial transcriptome is localized, yet the role(s) of mRNA localization in adult tissue homeostasis and function are unknown. Moreover, we still do not know how the transcript sorting machinery works, and we lack insights into the molecular composition of the membrane-less compartments that may maintain RNA segregation in the cytoplasm. We will address these gaps by combining RNA microscopy and subcellular proximity proteomics to study the functional contribution of RNA localization in digestive epithelia. Our project will comprehensively map the subcellular space across three adult epithelial tissues – liver, jejunum, and colon. To elucidate the mechanisms that mediate sequence-specific mRNA transport and maintain localization, we will develop a system to tether a construct for proximity proteomics to localized RNAs. We will functionally test the contribution of RNA localization to tissue homeostasis and disease development by disrupting the localizing elements and machinery. Our novel toolkit will enable the spatial mapping of RNA and proteins in parallel, allowing us to annotate the subcellular space and subsequently probe the biological significance of this fundamental process in adult epithelia. This novel technology can be extended to the subcellular study of all epithelia and tissues in general; it will ultimately lead to a more comprehensive understanding of tissue function in homeostasis and disease.

Keywords: intracellular mrna localization,epithelial polarity,digestive epithelia,gastrointestinal tract
EU integration and the Belt and Road Initiative: Investigating China’s global governance approaches and their implications for the EU (EUINTBRI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-11-01
End date: 2026-08-01
Duration (months): 36.0
Total project cost (EUR): 281358.72
EU funding (EUR): 281358.72
Participants: 1
Project status: SIGNED

The Fellowship's purpose is to make a comparative assessment of China’s soft power strategy in the context of the Belt and Road Initiative (BRI) and how a group of selected European countries (Italy, the Netherlands and Hungary) and the EU are engaging with and positioning themselves. The research analyzes the key components of the Initiative unlocking its vision, such as narrative, concepts and values; its modus operandi, intended as forms of engagement; its impact, in terms of scientific cooperation and education; and its prestige, on how China’s image is portrayed abroad. Through this comparative analysis, the research investigates how European countries are supporting, contraposing, and/or overlooking China's strategy assessing the implications for EU integration dynamics. The project’s overarching aim is to use the expertise from a representative of the policy sector (Fellow in charge) who has worked closely with the Chinese government and has direct access to Chinese sources, guided by a long-standing academic professor (researcher in charge) from a reputed European university and a profound expert in EU integration dynamics and the EU-China relationship to generate new knowledge and understanding. The project aims to strengthen a network of academic and policy stakeholders in Europe and China that can support a deeper understanding and dialogue, thus enhancing much-needed institutional collaboration between the theoretical and practitioners’ level. The Fellowship will intervene in the fields of international relations and EU integration studies. However, by promoting closer collaboration not only at subject and individual level but also at institutional level, the Fellowship is expected to generate greater partnerships across various disciplines via increases in the number of collaborations among European universities located in the selected countries and in China.

Keywords: china soft power,italy,the netherlands and hungary,comparative analysis,bri vision,modus operandi,impact,image,strengthen collaboration between the theoretical and practitioner s level
From biomass to compact inkjet-printed micro-supercapacitors: ink development, device printing and performance evaluation (LignoPrintCap)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-08-01
End date: 2024-07-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

Micro-supercapacitors (MSCs) are efficient power sources for miniaturized wearable/portable gadgets; a projected global market of over € 35 billion by 2025. However, MSCs still suffer from high-cost, low dimensional accuracy, and complexity in the fabrication process. This project aims to develop high performance, low-cost, greener compact MSCs through inkjet printing technology. To this end, we will develop a lignin-derived nitrogen-doped activated carbon ink and print the MSCs on flexible substrates. Subsequently, the compact size of MSCs will enable us to print a high number of MSCs into a small footprint area and connect them in-series/in-parallel. This will assist us to alter the cell voltage and capacitance. In addition, to get new insights into the effect of electrode properties on electrode/electrolyte decomposition and cycle stability, we will investigate the lignin-based carbon properties and electrode/gel electrolyte interface using advanced characterization techniques e.g. XPS, NEXAFS, XANES. The world-leading expertise of Prof. Magda Titirici (host); and the state-of-the-art facilities at Imperial College London, provide the perfect environment to successfully host my project despite its challenging nature.

Keywords: micro supercapacitor,inkjet printing,electrode electrolyte interface,lignin derived carbon
Wearable Neurotechnology for Sleep Quality Improvement (BetterSleep)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Spain
Call: European SME innovation Associate - pilot (H2020-INNOSUP-2020-02, 2020)
Start date: 2021-02-28
End date: 2022-02-27
Duration (months): 12.0
Total project cost (EUR): 160064.29
EU funding (EUR): 112045.0
Participants: 1
Project status: CLOSED

30% of adults in industrialized countries such as the United States, United Kingdom, Japan, Germany, and Canada do not get good quality sleep on a regular basis. Insufficient and poor sleep has been declared a "public health problem" as it is associated with a range of negative health and social outcomes, including unsuccess in school and in the labor market. In economic terms, poor sleep - or the lack of it - leads to significant economic losses (up to 411 and 138 B$/year in the US and Japan, respectively), and there is growing evidence indicating a strong association between short sleep duration and high mortality risks. This project explores the implementation of a new neurotechnology to improve sleep quality, aiming to penetrate the Global Sleep Tech Device Market that exceeded USD 9 billion in 2018 and is set to achieve over 16% CAGR by 2025, surpassing USD 27 billion. The novel, consumer-grade device is based on a unique EEG/TCS developed by Bitbrain and is a very recent research breakthrough finding in sleep quality improvement. The rationale of this project is Bitbrain’s need to hire highly qualified personnel in Sleep and EEG/TCS technology to explore this innovation, in combination with the difficulty of the company to access this type of personnel. The impact of the recruitment will be the implementation of a sleep R&D area in the company, and he/she will benefit from working in a very interdisciplinary R&D team with many training possibilities. The specific objectives of the innovation associate will explore the feasibility of employing this new wearable EEG/TCS for sleep quality improvement, evaluate its effectiveness in laboratory settings, and verify the potential to transfer these results to the real world. If successful, this new technology will be the first of its class to potentially impact a very important social issue effectively.

Keywords: neurotechnology,sleep