Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Auctions for Renewable Energy Support II (AURES II)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Coordination and support actions
Countries involved: Austria,Germany,Spain,Germany,Spain,Italy,Germany,Hungary,Netherlands,Denmark,United Kingdom,United Kingdom
Call: Market Uptake support (H2020-LC-SC3-2018-RES-SingleStage, 2018)
Start date: 2018-11-01
End date: 2022-04-30
Duration (months): 42.0
Total project cost (EUR): 2594057.5
EU funding (EUR): 2594057.5
Participants: 15
Project status: CLOSED

Building on the insights of the recently finalized AURES project, AURES II investigates auction design options in more detail to determine their policy performance depending on different of policy objectives and give recommendations on their use. We apply a multi-methodological approach, including literature review, theoretical analysis, case studies, surveys, and empirical and quantitative methods such as econometric analysis and model simulations. The project expands the empirical base created in AURES in several directions. It continues the monitoring of ongoing and planned auction schemes. Case studies will now be complemented by a comprehensive online auction database, and quantitative analysis of how auction design features affect auction performance. The effects of auctions are further explored in two directions: (i) Developments in RES sector value chains and innovation processes in reaction to auctions, and (ii) Changes in financing patterns of RES projects in reaction to certain auction design specifications. AURES II will inform currently ongoing auction-related policy debates: (i) Challenges of cross-border openings of auctions; (ii) the question of technology-neutrality, i.e. of combining two or more RES-E technologies in one auction; and (iii) future challenges, including the necessity for and requirements towards auctions due to changing electricity markets, generation patterns, and other framework conditions such as actor diversity. The multi-methodological approach is accompanied by a strong involvement of relevant stakeholders including policy makers and industry representatives. The project builds upon and expands the strong network from AURES, allowing policy makers and industry to exchange expectations, experiences and ideas. This active dialogue allows stakeholder to learn from best practice and facilitates capacity building across borders in Europe. AURES II contributes to the EC’s communication activities in the area of RES auction design.

Keywords: auction,tender,competitive bidding,renewable electricity support auction
Intuitive editing of visual appearance from real-world datasets (CHAMELEON)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Spain
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-11-01
End date: 2023-04-30
Duration (months): 78.0
Total project cost (EUR): 1629518.75
EU funding (EUR): 1629518.75
Participants: 1
Project status: CLOSED

Computer-generated imagery is now ubiquitous in our society, spanning fields such as games and movies, architecture, engineering, or virtual prototyping, while also helping create novel ones such as computational materials. With the increase in computational power and the improvement of acquisition techniques, there has been a paradigm shift in the field towards data-driven techniques, which has yielded an unprecedented level of realism in visual appearance. Unfortunately, this leads to a series of problems, identified in this proposal: First, there is a disconnect between the mathematical representation of the data and any meaningful parameters that humans understand; the captured data is machine-friendly, but not human friendly. Second, the many different acquisition systems lead to heterogeneous formats and very large datasets. And third, real-world appearance functions are usually nonlinear and high-dimensional. As a result, visual appearance datasets are increasingly unfit to editing operations, which limits the creative process for scientists, engineers, artists and practitioners in general. There is an immense gap between the complexity, realism and richness of the captured data, and the flexibility to edit such data. We believe that the current research path leads to a fragmented space of isolated solutions, each tailored to a particular dataset and problem. We propose a research plan at the theoretical, algorithmic and application levels, putting the user at the core. We will learn key relevant appearance features in terms humans understand, from which intuitive, predictable editing spaces, algorithms, and workflows will be defined. In order to ensure usability and foster creativity, we will also extend our research to efficient simulation of visual appearance, exploiting the extra dimensionality of the captured datasets. Achieving our goals will finally enable us to reach the true potential of real-world captured datasets in many aspects of society.

Keywords: computer graphics,visual appearance,intuitive edits
Nanophononic devices: from phonon networks to phonon CQED (NanoPhennec)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: France
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-02-01
End date: 2023-01-31
Duration (months): 72.0
Total project cost (EUR): 1499375.0
EU funding (EUR): 1499375.0
Participants: 1
Project status: SIGNED

Phonons (quanta of vibration) play a major role in many of the physical properties of condensed matter. One of the most striking features of acoustic phonons is their ability to interact with virtually any other excitation in solids. Recent progress in the design, fabrication and control of nanomechanical systems has paved the way to explore new frontiers in the classical and quantum worlds. Devices based on semiconductor quantum dots (QDs) have been recently demonstrated to perform as near-ideal single photon sources, a very promising platform for developing a solid-state quantum network. The phonon engineering, however, remains an unexplored knob in the quantum information toolbox. The goal of this project is to explore new horizons in nanophononics by developing novel phononic networks with full control on the phonon dynamics, and unprecedented structures capable of acoustically interact with single QDs, bridging the gap between nanophononics and semiconductor QD quantum optics. AlGaAs based semiconductor cavities are capable of confining simultaneously photons and phonons. The building blocks of the proposed research are semiconductor pillar microcavities and single QDs deterministically positioned to maximize their interaction with the confined electromagnetic and elastic fields. To achieve our main goal we set three major objectives: 1) To develop novel one- and three-dimensional optophononic resonators and develop appropriate phononic measuring techniques; 2) To engineer nanophononic networks working in the tens-of-GHz range; and 3) To demonstrate first phonon cavity quantum electrodynamics phenomena for a single artificial atom coupled to a phononic cavity. Shaping the phononic environment opens exciting perspectives for solid state quantum applications, by providing a full control over the main source of decoherence and actually using it as a powerful resource to eventually transfer the quantum information.

Keywords: acoustic phonon,micropillar cavity,purcell effect,quantum dots,nanophononics,coherent phonon generation,picosecond ultrasonics,phononic devices
Novel Thermoelectric Energy Solutions based on Flexible Thin-Film Materials (TES-FlexThin)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Finland
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-05-01
End date: 2017-04-30
Duration (months): 12.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

In this Proof-of-Concept project we will create a completely new kind of integrated energy solution platform based on thermoelectric (TE) heat energy harvesting materials that are capable of converting various types of heat flows directly into electricity. The strong basis for the project is the new oxide-based thermoelectric inorganic-organic hybrid materials discovered in the PI's ERC Advanced Grant Project “Molecular-Layer-Engineered Inorganic-Organic Hybrid Materials (LAYERENG-HYBMAT)”. These hybrid thin-film materials are fabricated by the combined atomic/molecular layer deposition (ALD/MLD) technique which uniquely allows for fabrication of highly conformal thin-film coatings on various flexible, sensitive, functional and/or nanostructured surfaces. Within this PoC project we will (1) design and construct a few prototype devices based on the flexible inorganic-organic thin-film thermoelectrics and (2) integrate the devices with novel material platforms (textiles, polymers, coatings). The novel integrated TE energy solutions will enable heat-based energy harvesting for usage scenarios that are not possible with the existing bulky and fragile TE materials/generators. In addition, (3) the market for flexible thermoelectric generators will be analysed and the commercialisation and the IPR strategies will be created for TE generation solutions.

Keywords: integrated flexible energy solutions,heat based energy harvesting,thermoelectrics,inorganic organic hybrid materials,flexible thin films,atomic layer deposition,molecular layer deposition
Wearable Electroactive Fabrics Integrated in Garments (WEAFING)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Sweden,Sweden,France,Netherlands,Netherlands
Call: Flexible and Wearable Electronics (H2020-ICT-2018-2, 2018)
Start date: 2019-01-01
End date: 2023-12-31
Duration (months): 60.0
Total project cost (EUR): 3844862.5
EU funding (EUR): 3844862.5
Participants: 7
Project status: SIGNED

WEAFING will develop innovative garments with integrated textile actuators, sensors, and electronics for haptic stimulation. We will advance the technology and manufacturability of electroactive fabrics resulting in lightweight and flexible textile actuators. Integration of the actuators in wearables takes into account different textile morphologies, soft mechatronics, producibility, and human perception. The garments developed will have a high level of wearability as the actuator is the garment itself and the technology is silent. These wearables are based on a new kind of textile muscles that are also enhanced within the project. In wearable technology, most R&D comprises sensors and only very little concerns wearable actuator technology. There is a limited set of actuators for wearables and 95% of the applications for haptic feedback are based on vibration motors. Textile muscles offer a completely novel and different quality of haptic sensation. Furthermore, being textiles they offer a new way of designing and fabricating wearable haptics and can be seamlessly integrated into garments. They are silent, use low driving voltages, lightweight, soft and pliable, in contrast to other solutions that most often are hard, bulky and noisy. For these novel form of textile muscles we foresee a huge range of possible applications in haptics: for ergonomics, wellness, gaming, inclusion, or social communication. Electromechanically active polymers form a basis for the textile muscles. When low voltage is applied to the coated yarns, they contract. Processing the yarns into textiles multiplies the effect of the contraction and/or delivered force, depending on the textile construction. In a co-design approach involving end-users we will develop demonstrator garments for haptic stimulation and investigate their properties in a multidisciplinary team with members from chemistry, physics, soft mechatronics, textile technology, human perception and cognition, and wearable design.

Keywords: haptic stimulation,textile actuators,electro active polymers,soft mechatronics,co design,human perception and cognition
SUPAIR Spectroscopy: Single-Use Process Analytical Infrared Spectroscopy (SUPAIR Spectroscopy)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-09-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The biopharmaceutical industry is poised to reach an impressive market size of more than €300 billion by 2025. The production of biologic drugs is usually performed by cultivating mammalian cells within bioreactors. Those reactors are increasingly being monitored online by means of Process Analytical Technologies (PAT). However state-of-the-art techniques render both sub-optimal product quality and product efficiency. A complete mid-infrared (MIR) spectroscopy system using online Attenuated Total Reflectance (ATR) probes is highly expensive costing around €200,000, €20,000 only for the probes that are not robust enough, requiring consecutive sterilization to be reused (raising water and energy consumption). IRUBIS GmbH team goal is to make online monitoring of (single-use) bioreactors affordable. IRUBIS innovation comprises a single-use patent-pending silicon ATR crystal integrated in a single-use ATR Flow Cell which is read out by a compact Fourier Transform Infrared (FTIR) Spectrometer. IRUBIS Analytical Technology offers a system that will allow for the first time real-time process control (online) in single-use bioreactors. This means a flexible, highly automated system solution that costs half the price of the competing solutions. Furthermore, it eliminates sterilization requirements allowing for important energy savings. IRUBIS has been awarded an accelerator program promoted by Merck; Company recent merits also include the Medical valley award (€500,000) and the Exist scholarship (€150,000). Our business model will be based in two revenue streams: B2B direct sales of developed IRUBIS optical sensors to biopharma companies and sales through partnerships with distributors. The feasibility study we will carry out under this SME Phase 1 project, will define the technical, market and commercial roadmap allowing to offer customers a higher value product.

Keywords: process analytical technologies,bioprocessing technologies,mid infrared spectroscopy,ftir atr spectroscopy,online monitoring of bioreactors
Dissecting to hit the therapeutic targets in nucleophosmin (NPM1)-mutated acute myeloid leukemia (ContraNPM1AML)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Italy
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-04-01
End date: 2022-03-31
Duration (months): 60.0
Total project cost (EUR): 1883749.68
EU funding (EUR): 1883749.68
Participants: 1
Project status: CLOSED

Acute myeloid leukemia (AML) is a group of hematologic malignancies which, due to their molecular and clinical heterogeneity, have been traditionally difficult to classify and treat. Recently, next-generation, whole-genome sequencing has uncovered several recurrent somatic mutations that better define the landscape of AML genomics. Despite these advances in deciphering AML molecular subsets, there have been no concurrent improvements in AML therapy which still relies on the ‘antracycline+cytarabine’ scheme. Hereto, only about 40-50% of adult young patients are cured whilst most of the elderly succumb to their disease. Therefore, new therapeutic approaches which would take advantage of the new discoveries are clearly needed. In the past years, we discovered and characterized nucleophosmin (NPM1) mutations as the most frequent genetic alteration (about 30%) in AML, and today NPM1-mutated AML is a new entity in the WHO classification of myeloid neoplasms. However, mechanisms of leukemogenesis and a specific therapy for this leukemia are missing. Here, I aim to unravel the complex network of molecular interactions that take place in this distinct genetic subtype, and find their vulnerabilities to identify new targets for therapy. To address this issue, I will avail of relevant pre-clinical models developed in our laboratories and propose two complementary strategies: 1) a screening-based approach, focused either on the target, by analyzing synthetic lethal interactions through CRISPR-based genome-wide interference, or on the drug, by high-throughput chemical libraries screenings; 2) a hypothesis-driven approach, based on our recent gained novel insights on the role of specific intracellular pathways/genes in NPM1-mutated AML and on pharmacological studies with ‘old’ drugs, which we have revisited in the specific AML genetic context. I expect our discoveries will lead to find novel therapeutic approaches and make clinical trials available to patients as soon as possible.

Keywords: acute myeloid leukemia,npm1,gene mutations,target therapy,synthetic lethality,preclinical models
Civil Cyber Range Platform for a novel approach to cybersecurity threats simulation and professional training (CYBERWISER.EU)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Improve cyber security
Action type: Innovation actions
Partnership: Cybersecurity PPP (cPPP)
Countries involved: Italy,Spain,Italy,Italy,Belgium,Norway,Slovenia,Netherlands,Portugal,United Kingdom
Call: Cybersecurity PPP: Addressing Advanced Cyber Security Threats and Threat Actors (H2020-DS-SC7-2017, 2017)
Start date: 2018-09-01
End date: 2021-02-28
Duration (months): 30.0
Total project cost (EUR): 5323407.5
EU funding (EUR): 4134245.0
Participants: 17
Project status: CLOSED

CYBERWISER.EU pragmatically addresses, in the DS-07-2017 call, the urgent need to count on highly-skilled, multi-disciplined cybersecurity professionals, given the increasingly aggressive cyber-landscape that Europe and the world is facing. CYBERWISER.EU will be an educational, collaborative, real-time civil cyber range platform where cybersecurity competitions will take place, making it the EU’s reference, authoritative, independent cybersecurity platform for professional training. Users can play the role of attackers and/or defenders in different scalable and configurable scenarios, composed of a set of virtual resources representing a company ICT infrastructure. The platform will be completely web-based, to facilitate adoption, collaborative support from end-users and continuous upgrade. CYBERWISER.EU expands and builds on the results and users community of the H2020 IA named WISER [2015-2017], thereby providing a jump-start situation from a consolidated raising awareness and past investment point of view. The 9 domain-skilled partners from 7 European Countries bring relevant assets to the project and are complementary and include 3 full-scale pilots (2 of which in critical infrastructures), viz.: 1. energy distribution; 2. railroad transport; 3. High Education, in the specific context of a University Master course on cybersecurity. An influential Stakeholder Expert Board (SEB) supports the consortium. Main Outputs: An Innovative, fully integrated cyber range platform; economic risk models attack patterns with mitigation measures; specialised training documentation with methodology; 3 Full-scale Pilots; one Open Pilot Stream targeting 500+ individuals from at least 5 different verticals; 750+ trained professionals; Sustainability model & business plan. High visibility through 4 workshops, 2 hackathons, 6 webinars, presence at 50+ specialised events. Profiled database of 2000+ records from 11 stakeholder groups.

Keywords: cyber range,training,cyber attacks,simulation environment,tools,models,performance evaluation,cyber threat detection,cyber threat response
Industrial Production of Stable Fibroblast Growth Factors for Regenerative Medicine and Related Research Areas (FGFSTAB)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Czechia
Call: Supporting innovative SMEs in the healthcare biotechnology sector (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2017-03-01
End date: 2019-02-28
Duration (months): 24.0
Total project cost (EUR): 1030000.0
EU funding (EUR): 1030000.0
Participants: 1
Project status: CLOSED

The FGFSTAB project closes the gap between Enantis knowledge and expertise on protein engineering and the commercial applications of stable fibroblast growth factors (FGFs). FGFs are essential to the embryonic development, maintain tissue homeostasis, may slow down ageing of the organisms, and primarily promote angiogenesis and wound healing. FGFs see the greatest application in the care and treatment of chronic skin ulcers, but find use also in surgical and trauma wound healing. The global wound care market is rapidly growing due to the rising aging population and growing incidences of obesity and diabetes. Advanced wound dressings, such as those involving growth factors, play an important role in current regenerative medicine and companies around the world have started investing heavily in research and development of growth factor-based products. However, despite clinical value, applications of FGFs are limited by the fact that natural proteins have poor thermal stability and a short half-life in the circulation; they are often cleared from the body within hours, if not minutes, thus necessitating frequent administrations during the course of treatment, which goes hand in hand with a higher risk of adverse effects and lower cost-effectiveness of the protein therapy. The key objective of the FGFSTAB project is to use an innovative technological platform, based on the application of Enantis proprietary protein optimization concept FireProt, to increase FGF stability under various stress conditions. Additional challenges including high cost of production, current Good Manufacturing Practise, development of delivery systems for safe and effective wound healing, and pre-clinical testing to support future clinical trials and marketing authorization, will be targeted as well. Financial support provided within SME Instrument phase 2 will help us to close the gap from demanding biotechnological development to the target industrial application in regenerative medicine.

Keywords: fibroblast growth factors,therapeutic proteins,protein stability,protein engineering,regenerative medicine,advanced wound healing,stem cells