Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
New Robust DESIgn Guideline for Imperfection Sensitive COmposite Launcher Structures (DESICOS)

Framework: FP7 — Cooperation
Programme: Space
Destination: Strengthening the foundations of Space science and technology
Action type: Collaborative project
Countries involved: Germany,France,Germany,Netherlands,Germany,Italy,Latvia,Germany,Israel,Germany,Australia
Call:  (FP7-SPACE-2011-1, 2011)
Start date: 2012-02-01
End date: 2015-07-31
Duration (months): 42.0
Total project cost (EUR): 3098287.44
EU funding (EUR): 1997700.0
Participants: 12
Project status: CLOSED

European Space industry demand for lighter and cheaper launcher transport systems. The proposed project DESICOS contributes to these aims by a new design approach for imperfection sensitive composite launcher structures, exploiting the worst imperfection idea efficiently: the Single Perturbation Load Approach. Currently, imperfection sensitive shell structures prone to buckling are designed according the NASA SP 8007 guideline using the conservative lower bound curve. The guideline dates from 1968, and the structural behaviour of composite material is not considered appropriately, in particular since the imperfection sensitivity of shells made from such materials depends on the lay-up design. The buckling loads of CFRP structures may vary by a factor of about 3 just by changing the lay-up. This is not considered in the NASA SP 8007, which allows designing only so called "black metal" structures. Here is a high need for a new precise and fast design approach for imperfection sensitive composite structures which allows significant reduction of structural weight and design cost. For most relevant architectures of cylindrical and conical launcher structures (monolithic, sandwich, isogrid - without and with holes) DESICOS will investigate a combined methodology from the Single Perturbation Load approach and a specific stochastic approach which guarantees an effective and robust design. A recent investigation demonstrated, that an axially loaded unstiffened cylinder, which is disturbed by a large enough single perturbation load, is leading directly to the design buckling load 45% higher compared with the respective NASA SP 8007 design. All results will be summarized in a handbook for the design of imperfection sensitive composite structures. The potential will be demonstrated within different industrially driven use cases.

Keywords: composite structures,stability,imperfection sensitivity,design guidelines,analysis,experiments,testing,validation,design handbook
CAncer Risk and INsulin analoGues (CARING)

Framework: FP7 — Cooperation
Programme: Health
Destination: Other Actions across the Health Theme
Action type: Collaborative project
Countries involved: Netherlands,Denmark,Norway,Sweden,Finland,Finland,Netherlands
Call:  (FP7-HEALTH-2011-single-stage, 2011)
Start date: 2011-11-01
End date: 2015-10-31
Duration (months): 48.0
Total project cost (EUR): 3834396.4
EU funding (EUR): 2974173.75
Participants: 7
Project status: CLOSED

Several studies have linked the use of insulins to the risk of cancer, and it is certainly plausible that as a growth factor, exposure to administered insulin could stimulate neoplastic growth. However, the meta-analyses of randomized clinical trials comparing different insulin analogues were too small to quantify the risks, especially the proportion of patients that were followed for more than 6 months. Hence, the European Medicines Agency has requested urgent research to determine the risks of cancer for users of insulin and insulin analogues, and investigate possible mechanisms of cancer promotion. CARING will obtain precise data on the incidence of cancer in diabetic patients and determine any link with use of various insulin and insulin analogues. The study will utilise high quality prescription databases and other national datasources, integrated at European level with advanced methods of harmonising data. The study will take into account potential confounders. The project aims to determine the influence of drug dose on risk, and through a risk model, identify predictors of cancer for insulin users. A review of published evidence combined with a study of tumour characteristics and gene expression in breast cancer tumour collections will aid understanding of potential mechanisms of cancer initiation and/or promotion by insulin. The project consortium involves some of the most experienced pharmacoepidemiology groups in Europe, and a leading cancer research institute. The consortium will liaise closely with the European Medicines Agency and other stakeholders throughout the study.

Keywords: pharmacoepidemiology,type 2 diabetes mellitus,breast cancer,genetic tumour profiling,risk stratification
ASSESSMENT OF THE SAFETY OF LABAS IN ASTHMA IN ROUTINE CARE BY COMBINING HEALTH-CARE DATABASES AND DIRECT PATIENT FOLLOW-UP (ASTRO-LAB)

Framework: FP7 — Cooperation
Programme: Health
Destination: Other Actions across the Health Theme
Action type: Collaborative project
Countries involved: France,United Kingdom,France,Netherlands,Spain,Netherlands,United Kingdom
Call:  (FP7-HEALTH-2011-single-stage, 2011)
Start date: 2011-12-01
End date: 2016-05-31
Duration (months): 54.0
Total project cost (EUR): 4073707.21
EU funding (EUR): 2979996.0
Participants: 8
Project status: CLOSED

Background: The efficacy of long-acting β-agonists (LABAs) in asthma has been demonstrated but their safety remains an issue, particularly in children. Co-therapy with inhaled corticosteroids (ICs) is recommended in persistent asthma. However, drug-use studies suggest frequently inadequate IC adherence, possibly explaining the occurrence of exacerbations. There is a need for detailed analyses of patterns of use of LABAs and ICs to describe asthma outcomes related to LABAs in monotherapy and at different levels of concomitant ICs, to explore the role of adherence in LABA safety, and to identify populations possibly at risk of adverse LABA-related asthma outcomes. Methods: Summarise available evidence on the risks of LABAs in asthma; develop questionnaires and instruments for the study; identify, in the UK and France, paediatric (6-15) and adult (16-40) patients with persistent asthma treated by LABAs; and link distinct datasets for this group using past and ongoing prescriptions provided by GPs and identified from electronic health records, dispensed therapy identified from claims data, information collected from prescribers, and details on exposures and outcomes collected by computer-assisted telephone interviews with patients over a prospective 24-month period. Analyze the linked datasets to characterise individual asthma care in detail and with high validity, describe patterns of use of LABAs and ICs, and relate these patterns to asthma outcomes. Disseminate results to the scientific community, patients’ associations, physician’s associations, and regulators. Deliverables: Ranking of observed patterns of LABA and IC use according to risk of adverse outcomes due to LABAs. Identification from prescriber and patient data of predictors of patterns of use which put patients at risk. Results for regulators to use regarding recommendations to prescribers and patients on the use of LABAs. Assessment of the potential impact of these recommendations on public health.

Keywords: safety / laba / adherence/ children / population impact/ asthma/ electronic medical records/epidemiology/risk/ exacerbation
A framework for enhancing EO capacity for Agriculture and Forest Management in Africa as a contribution to GEOSS (AGRICAB)

Framework: FP7 — Cooperation
Programme: Environment (including Climate Change)
Destination: Earth observation and assessment tools for sustainable development
Action type: Collaborative project
Countries involved: Belgium,Kenya,Belgium,Netherlands,Mozambique,Niger,Netherlands,Senegal,Tunisia,South Africa,Brazil,Spain,Italy,Ethiopia
Call:  (FP7-ENV-2011, 2011)
Start date: 2011-10-01
End date: 2015-03-31
Duration (months): 42.0
Total project cost (EUR): 4119542.8
EU funding (EUR): 3499234.2
Participants: 17
Project status: CLOSED

AGRICAB aims to strengthen Earth Observation (EO) capacities in Africa by building on the open data sharing through GEONETCast, connecting the available satellite and other data with predictive models in order to facilitate integration in agriculture and forestry planning and management processes. Dedicated national applications in various African countries are designed to address particular policy issues related to livestock, crop systems and forest management. Through these applications, “twinning partnerships” are developed between a European and an African partner, to maximize knowledge transfer and integration. Experiences learned will form a good basis for regional trainings to the member states of the Observatoire du Sahara et du Sahel (OSS) in Tunisia, the Regional Centre for Mapping Resources for Development (RCMRD) in Kenya and the AGRHYMET regional centre in Niger, covering almost the entire African continent. These activities will be linked with Africa-wide management and research initiatives and programmes on Forest and Agriculture and builds on experiences from the GEONETCast for and by Developing Countries (DevCoCast) and Global Monitoring for Food Security (GMFS) projects.

Keywords: agriculture,forestry,africa,geoss,geonetcast,capacity building,predictive models
MOTivational strength of ecosystem services and alternative ways to express the value of BIOdiversity (BIOMOT)

Framework: FP7 — Cooperation
Programme: Environment (including Climate Change)
Destination: Sustainable management of resources
Action type: Collaborative project
Countries involved: Netherlands,United Kingdom,Belgium,Germany,Finland,Slovenia,Italy,Netherlands
Call:  (FP7-ENV-2011, 2011)
Start date: 2011-09-01
End date: 2015-08-31
Duration (months): 48.0
Total project cost (EUR): 4047522.4
EU funding (EUR): 3152839.0
Participants: 8
Project status: CLOSED

People in Europe acknowledge that nature is important to them and to society at large. Economists have shown that indeed, biodiversity has total economic values running into the trillions of euros worldwide and hundreds of millions even for ‘minor’ ecosystem services on local scales. In spite of these immense values, politicians and the general public in Europe do not appear to really act for nature. In the ballot box, people think about their job security, their mortgage or foreign immigrants – not about the loss of nature. Politicians feel tempted to focus on these same narrow issues. As a result, European biodiversity continues to decline. Can economic methods to assess the value of biodiversity be improved such that they reach out to what really motivates action? Can alternative approaches be developed that lie closer to what connects people to nature and can appeal to their actions in stead of only to their feelings? The BIOMOT project, funded by the FP 7 programme of the European Union, will address these challenges. Involving eight research institutes in seven European countries and uniting a unique group of economists, governance experts, psychologists and philosophers, BIOMOT will undertake empirical research in the seven European countries, focusing on (a) the motivational capacity of economic valuation methods, (b) the types of motivation for nature that underlie successful policy actions for biodiversity at various scales and (c) the motivations that drive citizens, business and public leaders to take action for nature. On that basis, BIOMOT will develop a general theory of motivation for biodiversity and think through its implications for biodiversity policies, for business and civil society actors and for public communication.

Keywords: biodiversity,nature,value,economic valuation,non-economic value,governance,motivation,theory of motivation,image of nature,conservation,policy
ORganic waste management by a small-scale Innovative automated system of anaerobic digestION (ORION)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SME associations
Action type: Research for the benefit of specific groups
Countries involved: Ireland,Belgium,France,France,Italy,Switzerland,Spain,United Kingdom,United Kingdom,France,Türkiye,Ireland
Call:  (FP7-SME-2011, 2011)
Start date: 2012-08-01
End date: 2015-07-31
Duration (months): 36.0
Total project cost (EUR): 3880500.55
EU funding (EUR): 2978002.49
Participants: 21
Project status: CLOSED

Restaurants, hotels, markets, fisheries and other small to medium size agro-food industries have to manage 239 million tonnes of organic waste in Europe per year. The specific management of such waste, with respect to the legislative regulations of EU, involves costly treatment for SMEs and potential hygiene issues on site. ORION aims at allowing a vast majority of SMEs to manage their organic waste by themselves in order to decrease their treatment costs (storage, transport, landfill or incineration) and increase on-site hygiene conditions. Wastes will be also valorised as biomass to produce energy and increase SME autonomy and profitability. ORION main objectives consist of: Ø Developing for the first time anaerobic digestion machine at the SME scale (1 m3 to 50 m3) that will combine effectiveness for a large range of organic wastes and reduced capital and operating costs. Ø Developing advanced control tools and sensors to reach an optimum reliability Ø Increasing know-how on the impact of nanostructured surfaces on bacterial growth and increase waste throughput in the digestor Ø Developing a dissemination and training strategy in order to address a vast community of SMEs and offer them a personalized service Ø Contributing to the implementation of EU policies on waste management and renewable energies production. A maximum autonomy, adaptability and reliability are targeted. The digester is expected to be very cost-effective for users. ORION partnership is composed of European and National IAG representing the targeted sectors: fishery/aquaculture, hotel-restaurants, small agro-food industries and a Core Group of representative SME partners involved in the pilot design ND testing with various waste qualities and quantities. They will rely on a interdisciplinary group of research centers in order to achieve the technical goals of the project.

Keywords: organic waste
Ocean Strategic Services beyond 2015 (OSS2015)

Framework: FP7 — Cooperation
Programme: Space
Destination: Space-based applications at the service of the European Society
Action type: Collaborative project
Countries involved: France,France,United Kingdom,Belgium,France,Ireland,Germany,Türkiye,United Kingdom
Call:  (FP7-SPACE-2011-1, 2011)
Start date: 2011-11-01
End date: 2014-10-31
Duration (months): 36.0
Total project cost (EUR): 3357235.2
EU funding (EUR): 2000000.0
Participants: 11
Project status: CLOSED

The first level of GMES applications in the marine area is mostly represented by the "upstream" services of the MCS (e.g. MyOcean). Unfortunately, the current MyOcean offering of products and services for biogeochemistry has limitations that prevent a full uptake by the potential users. The present project proposes to address these issues through a range of R&D activities designed to offer a set of solutions that shall benefit the Marine Core Service beyond 2015. The outcomes of the project are expected to benefit both the upstream and downstream services of the MCS. To achieve this, the OSS2015 team will conduct R&D work in three areas: o The derivation of 3-D and 4-D representations of biogeochemical variables from the integration of gliders and floats in situ data and EO satellite data into cutting-edge numerical biogeochemical and bio-optical models. The models, assimilation schemes and output products from the models will be tested at two pilot sites (Mediterranean and North Atlantic) o The generation and validation of satellite derived global time series of advanced biogeochemical products (POC, NPP, PFT, PSD) for carbon cycle science. o The implementation of a prototype platform of "on-demand" services for product generation and distribution. This system of services will be tested and demonstrated with the new biogeochemistry products developed during the project. OSS2015 will also analyse the social and economical benefits and value of the products and services generated by the project. The OSS2015 team is a good balance of ten partners from six scientific research institutions and four SMEs and is designed to cover the needs of both science users and users interested in more applied services. A strong emphasis will be put on dialogue and interaction with users in order to identify their actual needs and adapt the OSS2015 services accordingly whenever possible.

Keywords: marine core services gmes biogeochemistry bio-optics models assimilation
Heterogeneity, Uncertainty and Macroeconomic Performance (HUMP)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Individuals, institutions and markets
Countries involved: Germany
Call:  (ERC-2011-StG_20101124, 2011)
Start date: 2012-01-01
End date: 2016-02-29
Duration (months): 50.0
Total project cost (EUR): 878800.0
EU funding (EUR): 878800.0
Participants: 1
Project status: CLOSED

Not least the Great Recession shows that micro-level uncertainty and borrowing constraints have first-order macroeconomic consequences and how their fluctuations influence business cycles. To understand many aspects of business-cycles, a vast literature highlights nominal rigidities to be pivotal. Nevertheless, almost all macroeconomic models abstract from these rigidities for tractability when introducing heterogeneous agents, uncertainty, and borrowing constraints. Vice versa, the nominal-rigidities, representative-agent approach, standard in business-cycle research, ignores micro uncertainty and heterogeneity outright; again for tractability. This significantly limits our understanding. With incomplete markets, it depresses consumption if micro uncertainty increases or borrowing constraints tighten. With flexible prices, this implies a boom driven by investment and an increase in labour supply. This contradicts empirical evidence showing that uncertainty is countercyclical. However, nominal rigidities could quantitatively align model prediction and evidence as they make aggregate output demand-determined. This motivates the proposed research project, where the first objective is to develop a quantitative framework that merges nominal rigidities with market incompleteness. I then analyse income risk from unemployment as a propagation mechanism and fluctuations in borrowing constraints as potential drivers of business cycles. As income risk from the labour market is a central to any incomplete markets model, these first projects are complemented by projects on the micro structure of job and worker flows, grasping frictions in hiring workers or creating jobs. These projects build on a unique data set generated by a small team around me at the Institute of Employment Research of the German Federal Employment Agency, which covers all quarterly worker- and job flows for the universe of German plants since 1975 with detailed information on workers and plants.

Keywords: computational macroeconomics,heterogeneous agent dsge models
The capacity of civil society organisations (CSOs) and their networks in community based environmental management (CIVI.NET)

Framework: FP7 — Cooperation
Programme: Environment (including Climate Change)
Destination: Earth observation and assessment tools for sustainable development
Action type: Research for the benefit of specific groups
Countries involved: Germany,Switzerland,Austria,Brazil,Netherlands,Costa Rica
Call:  (FP7-ENV-2011, 2011)
Start date: 2011-10-01
End date: 2014-09-30
Duration (months): 36.0
Total project cost (EUR): 2245360.0
EU funding (EUR): 1846660.0
Participants: 7
Project status: CLOSED

The CiVi.net project aims to analyse, transfer and disseminate successful and sustainable community based solutions with regard to ecosystem service management in Latin America. The main focus is placed on institutional settings in terms of original rules and related governance models which help to prevent and resolve tensions arising from a necessary new repartition and use of natural resources. Thereby, the role of civil society organisations (CSOs) within these governance models is in the core of the research. To meet these challenges, CiVi.net takes an action research and case study approach. The project has chosen four case study regions in Brazil and Costa Rica where successful solutions have been worked out. These will be analysed with respect to the following questions: - What kinds of management instruments are used to solve environmental problems and how effective are they? - What kinds of original rules and institutional arrangements are implemented and which economic governance models have been established? - What crucial aspects must be considered when transferring these solutions to other communities that face similar problems? - What is the capacity of CSOs and their networks for contributing to finding, implementing and transferring such solutions? Based on the findings, CiVi.net wants to facilitate the transfer of successful solutions to at least one other community for each selected case study region confronted with similar environmental challenges. To do so, CiVi.net will develop an ex-ante assessment approach to test the transferability of institutional solutions and of successful governance models. One of the final outputs will be a manual to assist practitioners and scientists on how to design and manage the knowledge transfer. CiVi.net will put much emphasis on the dissemination of the produced knowledge. Thus, another of its final outputs will be an innovative web-based data portal for providing and trading knowledge.

Keywords: community based management of natural resources,ecosystem services,management instruments,original rules,governance models,cso,civil networks,transfer