Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Assessing Activities of Daily Living from a Wearable RGB-D Camera for In-Home Health Care Applications (EGOVISION4HEALTH)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2012-IOF, 2012)
Start date: 2013-07-01
End date: 2016-06-30
Duration (months): 36.0
Total project cost (EUR): 265736.7
EU funding (EUR): 265736.7
Participants: 2
Project status: CLOSED

This project aims to develop the researcher‘s career to the point where he is in a very strong position to start his own research group and secure funding to do so. This will be achieved by complementing his existing scientific knowledge to give him a broad expertise on object detection, scene understanding and activity recognition, giving him training in complementary skills such as proposal writing, communication and management, allowing him to build collaborations and making him well-known throughout his research field through publications and conference attendance. The mobility objective is to transfer back to the EU the leading scientific expertise on object and activity detection in first person views only available at the Computational Vision Group at the University of California Irvine, USA, and to build long term collaborative links from this group to the return host, at Universidad de Zaragoza, experts in visual map building for mobile robotics. After project completion, the fellow is expected not only to go on researching in this emerging field, but also to make the technology transfer to produce commercial devices. This proposal aims at investigating the alloy between egocentric vision and visual map building to automatically provide the health professionals -occupational, rehabilitation and geriatric therapists- with an assessment of their patients’ ability to manipulate objects and perform activities of daily living (ADL). Research breakthroughs are required not only in vision-based ADL recognition and mapping but also in exploiting the synergy of the combination. The research objectives are: - to introduce the use of wearable RGB-D cameras and advance existing knowledge on object detection in first-person views, - to achieve advanced scene understanding by building a long-term 3D map of the environment augmented with detected objects, and - to analyse object manipulation and evaluate ADL using a detailed 3D hand model and the a-priori scene knowledge.

Keywords: computer vision,egocentric vision,activity recognition,object detection,rgb-d slam,semantic slam,life-long mapping,rehabilitation engineering,occupational therapy
Evaluation of ADAM-15 in atrial fibrillation (ADAM-15 AND AF)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2012-IOF, 2012)
Start date: 2013-06-01
End date: 2016-05-31
Duration (months): 36.0
Total project cost (EUR): 252742.2
EU funding (EUR): 252742.2
Participants: 1
Project status: CLOSED

Atrial fibrillation (AF) is the most common arrhythmia in Europe affecting more than 6 million people. AF is associated with significant mortality and morbidity including an increased risk for stroke, dementia and heart failure. Thus, AF is a major healthcare burden. The pathophysiology of AF is complex and still not fully understood. Increasing data support a genetic component to AF. Genome-wide association studies (GWAS) identified genetic variants associated with increased susceptibility for AF. However, the mechanism by which genetic variants influence the risk for AF is still unknown. At one AF risk locus with many genes, the top SNP is related to transcriptional levels of the metalloproteinase ADAM-15. Since ADAM-15 can activate inflammatory cytokines and regulate extracellular matrix turnover, it is a strong candidate gene for AF. To investigate the role of ADAM-15 in AF, the candidate, Dr. Sebastian Clauss, will characterize the cardiac phenotype of an ADAM-15 knockout mouse model. Dr. Clauss proposes to seek postdoctoral training in the laboratory of Dr. Patrick Ellinor at Massachusetts General Hospital and Harvard Medical School. During his training he will acquire new skills for characterizing mice including electrocardiography, echocardiography, invasive hemodynamics, electrophysiology (EP) studies, and optical mapping. This training opportunity would be a crucial step in Dr. Clauss’ career development as it will not only expand his scientific skills it will also enable the transfer of his knowledge and experience to Europe upon his return. Finally, he will establish a mouse electrophysiology facility in Munich that will provide the basis for his future career as an independent researcher and will further increase European research excellence.

Keywords: l407 cardiovascular diseases,atrial fibrillation,cardiac electrophysiology
Novel multizone thermodynamic model and specialised software for rapid optimisation of working process strategies and design parameters of Internal Combustion Engines run on advanced biofuels (BIO-GREEN-IC-ENGINE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-IIF, 2012)
Start date: 2013-12-02
End date: 2015-12-01
Duration (months): 24.0
Total project cost (EUR): 299558.4
EU funding (EUR): 299558.4
Participants: 1
Project status: CLOSED

International Energy Agency envisages that advanced biofuels will contribute significantly to reducing emissions by increasing from 2-3% of total transport energy supply today to 27% by 2050. Transportation experts propose that R & D of next-generation biofuels must be carried out in conjunction with the development of advanced combustion engines. At present very intensive R & D works are being conducted by all major internal combustion (IC) engine manufacturers on the development of engine designs capable to work on blends with up to 100% of biofuel. Similar works are being conducted on retrofitting the old park of motors. The main challenge in such activities is to satisfy EU regulations on emission levels. To successfully achieve this goal it is necessary to carry out a combination of fundamental theoretical and experimental research. One of barriers in conducting theoretical part of investigations is absence of specialised software dedicated to accurate modelling the operation of IC engines on different biofuel blends and which would allow developers to optimise the working process strategy and design parameters of engines. The main objective of the “Bio-Green-IC-Engine” project is the creation of the extensive database on properties of biofuels, development of the advanced multizone thermodynamic model for the simulation of IC engines operating on various advanced biofuels and incorporating it into user-friendly software for rapid optimization of high performance clean engine design parameters. The accuracy of the deployed model will be enhanced by using data from three-dimensional CFD modelling of the fuel spray evolution and detailed chemistry analysis of biofuels combustion. The developed software will be used for industrial, research and educational purposes across EU countries and will improve the technological and industrial practice related to manufacturing IC engines and their fuel supply systems to operate on advanced biofuels.

Keywords: g312 mechanical and manufacturing engineering,g203 simulation engineering and modelling,g306 energy systems
HYbrid III-V/Silicon laSer for the future generation of Photonic integrated circuits (HYSSOP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-03-01
End date: 2015-02-28
Duration (months): 24.0
Total project cost (EUR): 194046.6
EU funding (EUR): 194046.6
Participants: 1
Project status: CLOSED

The present project embraces the field of Silicon Photonics, which is expected to play a major role in the future of information and communication technology systems, especially datacenter interconnections, telecom infrastructures and consumer electronics interfaces. Silicon photonics has recently gained a tremendous amount of interest as a means to realize highly integrated optical devices and subsystems. The optical signal is guided in a silicon strip surrounded by silicon-dioxide. The high index contrast between these materials enables the realization of ultra-compact integrated optical devices. Active functions such as electro-optic modulators and detectors can be integrated and an ultra-tight integration of electrical and optical functions is fundamentally achievable. Tremendous advances were made in silicon photonics, demonstrating devices such as wavelength division multiplexing (WDM) filters and electro-optic modulators. However, practical Si-based light sources are still missing today. Such sources constitute the main technological roadblock hindering the development of silicon photonics based systems. The overall objective of the present project is to demonstrate the feasibility of III-V/Si lasers complying with the needs of the future generation of photonic integrated circuits. The mainstream approach is based on the development of quantum dash sources with disruptive performances in terms of power efficiency, noise and thermal stability, explored in conjunction with hybrid integration on a silicon-based platform. A staged approach based on four main technical objectives is proposed: 1) Demonstrate the feasibility of WDM transmission using hybrid lasers based on quantum dash active material. 2) Demonstrate the use of long silicon passive cavities for low-noise light generation. 3) Demonstrate the use of high-Q cavities for low noise light generation. 4) Demonstrate low time jitter hybrid mode-locked sources with pulse repetition rates in the GHz range.

Keywords: g205 micro- and nanoelectronics - optoelectronics,g206 communication technology - high-frequency technology,p109 lasers and laser physics,p207 semiconductors
Minority politics, social movements and equal rights: the Italian inter-associative LGBT activism (LGBT ACT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-09-16
End date: 2015-09-15
Duration (months): 24.0
Total project cost (EUR): 179739.6
EU funding (EUR): 179739.6
Participants: 1
Project status: CLOSED

Which sort of politics the lesbian, gay, bisexual and transgender activism (LGBT) promotes within the context of a country still highly homophobic? Which sort of discourses, collective actions, strategies and dilemma are underlying the emergence and the organisation of LGBT movements within the Italian society’s historical configuration of democracy? These are the questions this research will seek to answer in an empirically-based approach to LGBT politics. It is to build a multidimensional model of LGBT activism. Thus, the proposed research is threefold. First, the project proposes to study – through qualitative researches in the associative field – the “moments” of emergence and organisation of collectives, groups and associations of homosexuals, since the end of World War II until the creation of inter-associative LGBT networks in the 2000s in the light of historical and political transformations of society and the democratic configuration of Italian politics. Secondly, it is to analyse the discursive strategies, the collective actions and the alliance networks that contribute to the promotion of LGBT politics such plural as queer dissidence or equality rights. Thirdly, it is to problematise notions such as “identity” and “subjectivity”, “minority”, “recognition”, “justice”, “equality”, “visibility”, “autonomy”, and to propose a socio-historical approach to LGBT politics in Italy that permits to enrich current models and paradigms in political studies. Both in its empirical dimension as in its theoretical dimension, the project LGBT Act fills a real void, since no comprehensive scientific and methodical studies exist on the Italian LGBT movement, and the existing literature in political studies usually ignores the empirical conditions of the emergence and organisation of these groups.

Keywords: social movements,gender,sexuality,minority,equal rights,lgbt,political studies,identity,activism,political sociology,theories of democracy,italy,inter-associative networks,equality
The impact of asthma on dendritic cell development; analysis at the cellular and the molecular level (DC IN ASTHMA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2014-07-01
End date: 2016-06-30
Duration (months): 24.0
Total project cost (EUR): 169800.0
EU funding (EUR): 169800.0
Participants: 1
Project status: CLOSED

Allergic asthma is a chronic inflammatory disease of the airways and a worldwide problem. Dendritic cells (DC) have a key role in the development of this disease, making them interesting targets for therapy. Novel asthma therapies could involve interference with the development and relative abundance of functionally specialized lung DC subsets. Allergen exposure drastically changes airway DC subset distribution and preliminary experiments show effects on myeloid bone marrow progenitors. We hypothesize that DC precursor development, selection and differentiation choices are affected by allergen-induced airway inflammation and this might affect the outcome of the pulmonary immune response to allergens. Here, we aim to elucidate how asthma affects the distribution and differentiation capacity of DC progenitors/precursors at the cellular and the molecular level. In a novel house dust mite (HDM)-driven mouse asthma model, we will analyze HDM-induced changes in the distribution of bone marrow, circulating and lung-resident progenitors/precursors. In vitro development of progenitors/precursors isolated from HDM-exposed and control mice will be compared to identify imprinting effects on differentiation capacity. To find the mechanism by which asthma alters or imprints DC development from progenitors/precursors, HDM and asthma-associated cytokines will be added to in vitro DC differentiation cultures to evaluate their effects on development. The most promising candidates will be tested by analyzing DC development in HDM-exposed knockout mice and 50/50 mixed bone marrow chimeras. Moreover, gene expression profiles from progenitors/precursors isolated from HDM-exposed and control mice will be compared to identify new regulatory networks. Finally, findings will be validated in in vitro human DC differentiation cultures and human immune system mice. These data will help to define crucial DC development pathways during asthma that may be amenable to therapeutic intervention.

Keywords: asthma / dendritic cell subset development / mouse and human / hematopoiesis / inflammation
Self Assembled Monolayer Tunnel Junctions Engineering with Eutectic Gallium Indium Tips (SAM-TUNEGAIN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,Spain
Call:  (FP7-PEOPLE-2012-IOF, 2012)
Start date: 2013-06-01
End date: 2016-07-31
Duration (months): 36.0
Total project cost (EUR): 254925.9
EU funding (EUR): 254925.9
Participants: 2
Project status: CLOSED

The objective of this project is to gain control on the mechanism of transport properties of Self Assembled Monolayer (SAM)-based molecular tunnel junctions. The methodology developed by the Whitesides group over the last few years has allowed to increase the reliability of molecular tunnel junctions, allowing to measure their tunnel transport rates with much more accuracy than it had been possible until now, demonstrating how SAMs of alkylthiolates on Ag with odd or even number of atoms show different conductivities. The Whitesides group has also demonstrated the efficient rectification of Fc-terminated SAMs and suggested a mechanism to explain this result. In this project, we propose to rationally engineer the orbital energies of SAMs terminal groups in order to obtain predictable tunneling and/or hopping behaviors. The good development of this project will require the fellow to identify the target molecules by Ab Initio calculations, to engage in organic synthesis to prepare them, and to use a wide range of material science techniques to prepare, characterize and analyze the transport properties of their SAMs. The knowledge acquired by the fellow in Prof. Whitesides group in Harvard will then be transferred to the use of tunnel junctions bearing molecular magnetic end-groups, including SIngle Molecule Magnets, and potentially allowing to design and prepare highly magnetoresistive junctions. The outcome of this work would on one hand improve the fundamental knowledge on molecular tunnel junctions, potentially allowing to use them for molecular electronics, and could provide highly functional molecular spintronics devices by fine tuning of their spin injection barriers.

Keywords: c105 surface science,c107 chemical physics,c128 nanomaterials,c142 molecular chemistry,p214 molecular electronics
Electrically Controlled Protein Conformation on 3D Tissue Scaffolds (PROTEPROBE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-05-01
End date: 2015-10-30
Duration (months): 24.0
Total project cost (EUR): 269743.8
EU funding (EUR): 269743.8
Participants: 1
Project status: CLOSED

ProtEprobe takes advantage of the recent cutting edge developments in protein conformation control at the Malliaras group and high sensitive protein sensing using high sensitivity factor triangular silver nanoplates by the fellow. Misfolding of a protein occurs when it becomes trapped in a local potential energy minimum where the conformation differs from the native-state structure. External electric fields have been demonstrated to distinctly alter protein secondary structures. Proteins associated with protein misfolding diseases, incuding neurodegenerative diseases such as Alzheimer's, undergo conformational changes such as the transformation of largely random coiled or α-helix structures to the highly ordered β-structures found in protein fibrils. Amyloid fibrils formed from peptide Amyloid beta (Aβ), are a major component of amyloid plaques in the brains of Alzheimer’s patients. The ProtEprobe technique will use electrical potential gradients to stimulate and control the conformation transitions of proteins including the cell adhesion protein Fibronectin and Aβ on 3D electrospun conductive polymer tissue scaffolds. The high sensitive spectral response of the nanoplate monitors will be used to analyse protein conformational transitions and observe the progression of Aβ fibril formation. Investigations will be carried out to ascertain the impact of the presence of an electric field and the capacity to tune the strength in order to enable improved understanding and selection of protein conformations on tissue scaffolds, towards enhancing cell surface interactions, healing of misfolding and facilitating the restoration of the structure and function of diseased tissues. In a paradigm step towards imparting a new dimension to tissue regeneration, ProtEprobe will develop 3D bioactive scaffolds with electrically programmable protein conformation and in situ real-time protein nanomonitors paving the way for the treatment and prevention of many neurodegenerative diseases.

Keywords: p212 nanophysics,p303 nanochemistry,p304 spectroscopic and spectrometric techniques,p320 medical physics,l106 biophysics,c113 physical chemistry of biological systems,c128 nanomaterials
The moral foundations of activism (TMFOA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-IEF, 2012)
Start date: 2013-06-01
End date: 2015-05-31
Duration (months): 24.0
Total project cost (EUR): 221606.4
EU funding (EUR): 221606.4
Participants: 1
Project status: CLOSED

The proposed project will address the role of moral conviction in collective action: i.e. cooperative effort toward social change such as the Occupy movement and the Arab spring. Existing theory and research indicates that strong, long term commitment to social change results from a politicization process wherein individuals come to identify with a social movement and internalize its norms and values, resulting in action on its behalf. We argue that this politicization process results in the formation of a moral conviction about the goal of collective action, and 1) that this moral conviction is responsible for the effects of politicization on collective action readiness, but also that it has the potential 2) to sour the relation between activists and non-activists and to lower activists’ ability to attract followers, and 3) to lead to the dehumanization of political opponents and to justify the use of aggressive forms of collective action. Building on his established expertise, the Fellowship enables Dr. Zaal to provide a novel perspective on engagement in collective action, and to offer new insights in the mobilization and radicalization processes that are vital to understanding social change but have received little attention in the collective action literature. The proposed project provides the ideal opportunity for Dr. Zaal to achieve these research objectives and to develop a position of professional maturity. During the project, Dr. Zaal will benefit greatly from regular face-to-face meetings with Professor Barreto, an internationally renowned expert on social change, and from the training he will receive from her on social identity, social influence, morality and dehumanization. In addition, Dr. Zaal will benefit from being embedded in the Social, Environmental and Organizational Research Group, one of the most successful social scientific research groups worldwide, and from the complementary training opportunities offered by the University of Exeter.

Keywords: moral conviction,collective action,protest,mobilization,dehumanization,social change