Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Primary Biological Aerosol in the Atmosphere: Origins, Microphysical Processes, and Climatic Feedbacks (BIOAAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-04-01
End date: 2023-05-03
Duration (months): 24.0
Total project cost (EUR): 219312.0
EU funding (EUR): 219312.0
Participants: 1
Project status: SIGNED

Primary biological aerosols particles (PBAP) are emitted from the land and marine surfaces into the atmosphere, where they were found to be abundant. The PBAP are of high importance because of their potential involvement on ice-nucleation (IN) and precipitation formation processes, with potential implications on the climate. Older studies showed that the total concentration of PBAP is smaller than other types of ice-nucleation particles, e.g. dust, while recent studies showed that the reported concentrations of PBAP are highly underestimated, thus, their IN activity and climatic impacts have large uncertainty. According to the Fifth Assessment Report (AR5) of the Intergovernmental Panel on Climate Change (IPCC), the PBAP-cloud interactions, as a part of aerosol-cloud interactions, are still the least understood factor in our current understanding of climate change. In addition, combating climate change and its impacts is one of the Sustainable Development Goals of the United Nations. Therefore, it’s crucial to carry out further investigations on the emissions of PBAP and their consequent atmospheric microphysical processes and climatic impacts and feedbacks, which is the main objective of BIOAAT. The BIOAAT aims to: (i) deliver more realistic prediction of the emission flux and dispersion of PBAP; considering all ecosystems and meteorological conditions that lead to high variation in quantifying their concentrations, distributions, and emission fluxes, (ii) close the gap between observations and modelling studies on the impact of different types of PBAP on cloud ice and precipitation formation, and contribute to reducing the uncertainty of aerosol-cloud interactions, and (iii) ultimately delivers open-source models that describe the emission flux and ice nucleation rates of PBAP that can easily be implemented in different types of atmospheric models including climate models to better estimate past, present and future climate and environmental impacts of PBAP.

Keywords: aerosol cloud climate interactions,ice nucleation,biological aerosol,climate impacts,cloud micro physical processes
Polymeric Analogs to Biolubrication Systems (POLYBIOLUB)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2015-08-01
End date: 2020-10-31
Duration (months): 63.0
Total project cost (EUR): 2456570.0
EU funding (EUR): 2456570.0
Participants: 1
Project status: CLOSED

Lubrication in nature is based on water, but only functions due to the presence of a host of biomolecules. In articular (e.g. hip) joints, it appears that the lubrication system is even more complex than previously believed, involving multiple gradients in structures and properties. Gels and brushes appear to play an important role in biolubrication, while highly confined, highly hydrated charged polymers are key to the important mechanical properties of cartilage. Components such as hyaluronic acid, glycoproteins, and lipids all appear to act synergistically to yield the extraordinary tribological properties of the cartilage-synovial-fluid system. POLYBIOLUB seeks to mimic the mechanisms revealed by the latest studies of cartilage, by means of the synthesis of functionally similar polymeric structures. This is a completely novel approach to the problem, which has the promise not only of revealing structural dependencies of cartilage function, but also of yielding radically new, biomimetic, lubricious, low-wear materials that could find applications in either industrial or clinical environments. The principal synthetic tool will be controlled radical polymerization in a flow environment, involving in situ growth monitoring, followed by a series of postmodification and grafting steps, to yield structures that are lubricious, wear resistant, and tough. These efforts will be accompanied by extensive characterization of composition, structure and mechanical/tribological properties at each stage. Our group has extensive experience in controlled radical polymerization in a flow system, postmodification of polymers, brush-gel and layered polymer systems,. We also have over a decade of experience in water-based lubrication, natural lubrication, synovial-joint studies, and multidimensional gradient systems. The challenge now is to combine these skills to fabricate a completely new biomimetic material.

Keywords: multilayer structures,polymer brushes,gels,lubrication,gradients,biomimetic materials
Analysis of multimedia contents published on social networks, using a community of people willing to perform micro-tasks on their mobile devices. Application to marketing and branding (CAIN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2015-05-01
End date: 2016-02-29
Duration (months): 10.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Social networks contain valuable information for businesses. Companies able to understand what is said on social networks will have a significant competitive advantage. However, information extraction is not simple because it is not structured and because the volumes are very large. So far, algorithms have been developed to analyze texts inaccurately. But also the language of social networking is based on images and videos. Both formats growing faster than the text. The algorithms are far from understanding the meaning of multimedia contents, or extract useful information from them. Our solution assumes that today, and for a long time, this work can only be done by the human mind. Therefore we have the technology and methodology appropriate to do so. The analysis is performed by distributing micro-tasks to the mobile devices of a community of human solvers. The specific software creates micro-tasks, distributes it and reports the results. The micro-tasks are presented as games or activities that are resolved in less than 1 minute. The solvers are anonymous volunteers who perform the micro-tasks in exchange for an amount of money that is donated to the NGO of their choice. To participate, the solvers must download an application on their mobile devices. Virtually any business is a potential client of this solution, but especially those with brands targeted directly to consumers, with great presence in social networks. The scope of our project is first European and then global. The software and methodology have already been tested successfully in image analysis projects conducted by The Harvard University and the University of Barcelona. However, before marketing it is necessary to work on the value proposition meeting the information needs of businesses and testing the solution in a business environment. We also need to study the motivations of solvers to develop plans for growth of this community. Moreover the BP must be completed. These are objectives of Phase 1

Keywords: analysis of images and videos on social networks brand strategy and marketing crowdmobile mobile devices community micro tasking big data data mining multimedia engagement
Visualising memories of violence in urban places: gender and wellbeing in Istanbul (VISMEM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-10-01
End date: 2018-09-30
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 2
Project status: CLOSED

Evidence shows that violence in urban areas affects women of all ages, socio economic and cultural backgrounds in particular (WHO 2014). The immediate and extensive costs of violence targeting women perpetuate the existing gender hierarchies by setting boundaries on women’s movement, mobility, presence: that is, on their use of urban space. In addition to restrictions in mainstream social life, gendered violence is a systemic source of experiencing helplessness, humiliation, and distress which overall are a fundamental component of women’s wellbeing. VISMEM will investigate the impact of place-based memories of violence among diverse women for their use of urban space, and interrogate the utility of visual methods for understanding that impact. More precisely, the study uses visual methods to explore diverse women’s everyday negotiations of space in Istanbul, focusing in particular on their movements in relation to three research sites where forms of violence against women have occurred. VISMEM’s overall objective is to develop a conceptual framework and visual tools for multisector policy and research engagement with memory as a key means to locate, assess, and ameliorate women's differential experience of violence and wellbeing in the city. Women in different social and spatial settings remember (and forget) the physical and mental effects of violence through personal experience and through popular accounts of its effects. The differential workings of memory in turn have implications on the lived experiences and wellbeing of a city's current (and future) residents/visitors. Yet, the nexus of memory, place, gender remains disconnected from the multisector urban agenda on difference, inclusion, and wellbeing. VISMEM will provide transferable knowledge and policy-related results on the relation between gendered violence, memory, and will greatly improve our understanding of place memory as a focus in achieving gender-goals in urban social and spatial integration.

Keywords: gender,memory,place,visual methods,wellbeing,gender related violence,urban policy,social inclusion,diversity
From Topological Matter to Relativistic Quantum Vacuum (TOPVAC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Finland
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-10-01
End date: 2022-09-30
Duration (months): 72.0
Total project cost (EUR): 2159191.0
EU funding (EUR): 2159191.0
Participants: 1
Project status: CLOSED

The structure of relativistic quantum vacuum (RQV) in our Universe is one of the main challenges in modern physics. We plan to advance our understanding of the vacuum structure and on this basis treat the most important unsolved problems in physics, such as the cosmological constant problem (why the measured vacuum energy is 120 orders of magnitude smaller than estimates from the zero point motion) and the hierarchy problem (why the masses of the known particles in the Standard Model (SM) of particle physics are much smaller than the Planck energy). The quantum vacuum shares many common properties with topological matter. The goal of the proposal is to concentrate both theoretical and experimental efforts in the investigation of connections between the topological quantum matter and RQV, to enhance understanding of topological condensed-matter systems especially in the ultra-low-temperature regime, and to apply this experience to solution of problems in SM & cosmology. As a condensed-matter system we shall use superfluid phases of liquid 3He – unique topological materials, which are the most close to SM and gravity: Superfluid 3He-A, where the low-energy excitations are topologically protected Weyl fermions, gauge bosons, and gravitons, is similar to the vacuum of SM above the electroweak transition. The fully gapped topological superfluid 3He-B with its Higgs bosons is the counterpart of SM vacuum in its broken symmetry phase. In particular, theory of relaxation of dark energy will be accompanied by experimental study of resonant decay of coherent states of non-equilibrium superfluid vacuum. Determination of the topological classes of the quantum vacua of SM including the vacua with Majorana fermions will be accompanied by experimental studies of Majorana fermions on the boundaries of topological superfluids and in cores of quantized vortices. Theory of extra Higgs bosons in SM will be accompanied by experimental study of light and heavy Higgs modes in 3He-B.

Keywords: topological matter,superfluid 3he,majorana fermions,relativistic quantum vacuum,cosmological constant
Migrant Children and Communities in a Transforming Europe (MiCREATE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Research and Innovation actions
Countries involved: Italy,Iceland,Austria,Spain,Cyprus,Croatia,Slovenia,Greece,Poland,Slovenia,France,Portugal,Denmark,United Kingdom
Call: Mapping and overcoming integration challenges for migrant children (H2020-SC6-MIGRATION-2018, 2018)
Start date: 2019-01-01
End date: 2022-06-30
Duration (months): 42.0
Total project cost (EUR): 2840364.5
EU funding (EUR): 2840364.5
Participants: 16
Project status: CLOSED

The overall objective of the project is to stimulate the inclusion of diverse groups of migrant children by adopting a child-centred approach to their integration at the educational and policy level. Stemming from the need to revisit the integration policies on the one hand and consistent with the specific focus of the call on the other hand, the research project aims at comprehensive examination of contemporary integration processes of migrant children in order to empower them. The project starts from the fact that European countries and their education systems encounter manifold challenges due to growing ethnic, cultural, linguistic diversity and thereby aims at: 1) Identifying existing measures for the integration of migrant children at the regional and local level through secondary data analysis; 2) Analysis of the social impacts of these integration programmes through case studies in ten countries applying qualitative and quantitative child-centred research; 3) Development of integration measures and identification of social investment particularly in educational policies and school systems that aim to empower children. The project is problem-driven and exploratory at the same time. Its exploratory part mainly concerns a child-centred approach to understanding integration challenges, migrants’ needs and their well-being. However, the findings of the open-ended exploratory research will be used in an explicitly problem-driven way – with an aim to stimulate migrant inclusion, to empower migrant children and build their skills already within the (participatory) research. This will be done through the activities of the Integration Lab and Policy Lab, where children’s voices, fieldwork and desk research findings will be translated into practices and measures for educational professionals and practitioners as well as into a child-centred migrant integration policy framework to stimulate social inclusion and successful management of cultural diversity.

Keywords: migrant children,education,integration,child centered approach,reception communities,inclusion
Synthetic Cellularity via Protocell Design and Chemical Construction (PCELLS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-07-01
End date: 2023-12-31
Duration (months): 78.0
Total project cost (EUR): 2499238.0
EU funding (EUR): 2499238.0
Participants: 1
Project status: SIGNED

We propose to undertake an ambitious 5-year multidisciplinary programme that seeks to pioneer and establish a fundamentally new paradigm in protolife research that is based on novel conceptual and experimental advances in the design and construction of rudimentary forms of synthetic cell-like micro-ensembles (protocells). Our approach is positioned at the interface between materials chemistry, soft matter science and synthetic biology, and will address the following aspects of protocell design and construction: (i) functional complexity in protocell phenotypes, (ii) protocell self-structuring and metamorphosis, (iii) multi-compartmentalization and protocell endosymbiosis, and (iv) collective behavior in protocell communities. We will initiate unprecedented increases in the complexity of individual protocells by developing new types of structural architectures with advanced functions including photosynthetic protocells and motile proteinosomes, and develop innovative strategies for the chemical secretion of spatially extended extra-protocellular hydrogel matrices and induction of protocell metamorphosis. We will develop a modular micro-engineering approach to protocell multi-compartmentalization with the aim of generating coordinated enzyme- and gene-activated endosymbiotic interactions, and pioneer the experimental study of collective behaviour in communities of synthetic protocells. Our overall aim is to pioneer a modern approach to synthetic cellularity that advances the chemical and physical basis of protocell structure and function, and spearheads the development of future technologies based on autonomously functioning chemical micro-compartments with applications in bioinspired micro-storage and delivery, micro-reactor technologies, cytomimetic engineering, and the development of integrated constructs for diverse procedures in synthetic biology.

Keywords: biomimetic materials
Tau Pathology in Alzheimer’s disease: Spreading and Resilience (TAU-NOW)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Sweden,Netherlands
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-04-01
End date: 2026-03-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 860192.5
Participants: 2
Project status: SIGNED

Alzheimer’s disease (AD) poses a major challenge, as 40 million people worldwide are diagnosed with AD and there is currently no cure. AD is characterized by Aβ plaques and tau neurofibrillary tangles. Recently, several phase III clinical trials targeting the Aβ pathway have failed to reach their primary endpoints. This stresses the need for diversification of the drug portfolio. Tau pathology is a promising drug target due to its strong associations with synaptic density, atrophy and cognition. I envision two treatment options to be potentially effective in halting or slowing AD: 1) preventing the spreading of pathological tau, and 2) boosting resilience against tau pathology. Both processes are currently insufficiently understood, especially in living humans. Since a few years, AD-specific tau pathology can be measured in vivo using PET. TAU-NOW uniquely utilizes longitudinal tau PET in conjunction with functional and structural MRI, biofluid and cognitive data, to investigate mechanisms of tau spread and resilience in humans. In WP1, I will test the hypothesis that tau predominantly spreads through functionally connected regions, by relating tau PET changes over time to the functional architecture of the brain. Next, molecular (CSF) and genetic (GWAS) drivers of tau spread will be identified. On top of that, I will assess whether functional disconnection in subjects who underwent epileptic surgery (i.e. unilateral medial temporal lobe resection or corpus callosotomy) leads to an asymmetric tau PET pattern decades later. In WP2, I will investigate the functional (fMRI), molecular and genetic modifiers that render individuals resilient to tau pathology. In WP3, I will examine the consequences of tau spreading and resilience for important clinical trial outcomes like cognitive and volumetric changes over time. Altogether, TAU-NOW will enhance our understanding of tau spreading and resilience and may ultimately identify novel leads for drug discovery against AD.

Keywords: alzheimer s disease,spreading,resilience,neuroimaging,cognition,genetics
Rear End Aerodynamic and Aeroelastic Studies (TailSurf)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: United Kingdom,United Kingdom,United Kingdom
Call: Rear End Aerodynamic and Aeroelastic Studies (H2020-CS2-CFP09-2018-02, 2018)
Start date: 2019-10-01
End date: 2023-03-31
Duration (months): 42.0
Total project cost (EUR): 1465541.25
EU funding (EUR): 1465541.25
Participants: 3
Project status: SIGNED

TailSurf will contribute to the design, testing, integration and optimisation of ARE for the improvement of performance at component level of 20% weight reduction, 20% recurring cost reduction and 50% lead time reduction. It is also expected that 1.5% reduction of fuel burn at aircraft level will be achieved from the optimal rear end configurations. The specific objectives and the associated work packages to achieve this aim are shown below. 1. To define and test technologies and shapes to delay the flow separation, leading to stall of the tail surface and saturation of the control surfaces (WP1 – deliverable DX in MX). Thee control effect of these technologies and devices will be verified by both wind tunnel experiments and computational fluid dynamics (CFD) on high-performance computing (HPC) facilities. 2. To study means and concepts to increase aeroelastic efficiency of tail surfaces using computational and experimental means. 3. To study the integration of all technologies on an advanced rear-end configuration and numerical prediction and post-test calibration. 4. To investigate the applicability of plasma actuators (DBDs) for de-icing and delaying stall experimentally. 5. To carry out management and administration required over the course of the whole project. It will serve to administer and manage the project in accordance with the Clean Sky 2 Management Manual, including the management of risks, finances and administrative tasks. It will also be essential to promote the project results and scientific and technical outcomes through targeted dissemination and communication activities

Keywords: aerodynamics,aeroelasticity