Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Climate proofing future forest management (CLIMPRO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-11-01
End date: 2022-10-31
Duration (months): 24.0
Total project cost (EUR): 166320.0
EU funding (EUR): 166320.0
Participants: 1
Project status: CLOSED

The overall objective of this study is to quantify how adaptive management can affect the provision of ecosystem services, focusing on wood production, river runoff and climate change mitigation. The study will enhance our understanding of how adaptive management can contribute to climate change mitigation or, on the contrary, may exacerbate climate change while sustaining forest-based ecosystem services.

Keywords: ecosystem modelling,abrupt tree mortality,natural disturbance,adaptive management,earth system,model,coupled simulation
A smart, hybrid neural-computo device for drug discovery (NEUREKA)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Switzerland,Greece,France
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2019)
Start date: 2019-12-01
End date: 2024-05-31
Duration (months): 54.0
Total project cost (EUR): 2776705.0
EU funding (EUR): 2776704.0
Participants: 5
Project status: SIGNED

NEUREKA will bring a paradigm shift in drug discovery for neurological diseases, a sector that suffers multiple, repeated failures exacerbating the economical and societal burden of these incurable diseases. It will do so by addressing a crucial shortcoming: the lack of in vitro systems faithfully reproducing brain pathology that enable the functional assessment of candidate compounds at multiple levels: from synapses to neuronal circuits. NEUREKA introduces an innovative, hybrid technology, whereby detailed, computational neuronal networks simulate dysfunction and drive cultured neurons to replicate in-brain disease conditions. Nanoelectrodes mediate the transmission between simulated and biological neurons. Akin to real synapses, nanoelectrodes contact cultured neurons at subcellular locations across the dendritic tree, soma and axonal branches, allowing to control and monitor neural activity with unprecedented accuracy. Biological neuronal responses registered by nanoelectrodes are fed back to simulated neurons, closing the loop and enabling control of activity states across the hybrid population. Complementing molecular deficits already present in culture models of a disease, computational models enable replication of both molecular and physiological deficits of neurodegeneration in vitro. Cultured neurons are driven towards pathological excitability states where deficits emerge, so as to optimize quantification of the impact of drugs, going well beyond standard cellular assays. A proof-of-concept will be provided for Alzheimer’s disease, using human induced pluripotent stem cell (iPSC)-derived neurons exhibiting the pathology. NEUREKA will be used to demonstrate the effect of drug candidates across synaptic, neuronal and network functions.

Keywords: neuroelectronics,cell cultures,brain simulation,alzheimer s
Astronomy Fellowships in Italy 2 (AstroFIt2)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Fellowship programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Italy
Call: Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-FP) (H2020-MSCA-COFUND-2014, 2014)
Start date: 2015-09-01
End date: 2020-08-31
Duration (months): 60.0
Total project cost (EUR): 3823200.0
EU funding (EUR): 1911600.0
Participants: 1
Project status: CLOSED

INAF, the Italian National Institute for Astrophysics is proposing AstroFIt-2 in order to support transnational brain circulation of young researchers, by means of 18 Incoming Mobility 3-year fellowships to be issued in two calls, each of 9 fellows, to be carried out at the 17 INAF Research Centers across Italy. INAF, the Italian government’s public research body that promotes, performs and coordinates astrophysics research, also cooperates with universities and other national and international entities, and has approximately 1000 permanent staff, and more than 500 contractual scientific posts. INAF is internationally renowned for its excellent science and technology, and has prime responsibility in many international astrophysical programs. AstroFIt-2 thus gives young researchers experience, through working with international teams in highly relevant, world-class scientific and technological astrophysics projects. AstroFIt-2 builds on the success and experience acquired by INAF’s AstroFIt Cofund program, and so dramatically increases the quality and quantity of AstroFIt results in the following areas: • international mobility and brain circulation: by increasing the length (3 years vs 2) and number (18 vs 14) of fellowships; • efficiency, financial support, and user-friendliness of the program by: - increasing: a) the time for awarded fellows to reply to communications (45 days vs 15); b) the time between a fellowship being awarded and its start date (6 months vs 4); c) the living allowance (45.000 EUR/year vs 40.000) and the contribution to research and training expenses (6.000 EUR/year vs 5.000) - shortening: the evaluation process (4 months vs. 5); • inter-disciplinary and inter-sectorial research of the fellows by: - enhancing interactions and feedback between fellows and the Hosting Structure; - increasing the impact of the overall program in terms of scientific activity, transnational collaborations and inter-disciplinary experience.

Keywords: physical sciences,astronomy,incoming mobility
Intra-Logistics with Integrated Automatic Deployment: safe and scalable fleets in shared spaces (ILIAD)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Partnership: Robotics SPARC (cPPP)
Countries involved: Germany,Germany,Italy,Germany,Italy,Sweden,Sweden,Sweden,United Kingdom,United Kingdom
Call: System abilities, development and pilot installations (H2020-ICT-2016-1, 2016)
Start date: 2017-01-01
End date: 2021-06-30
Duration (months): 54.0
Total project cost (EUR): 6987715.36
EU funding (EUR): 6987715.36
Participants: 10
Project status: CLOSED

Today, intralogistic services have to respond quickly to changing market needs, unforeseeable trends and shorter product life cycles. These drivers pose new demands on intralogistic systems to be highly flexible, rock-solid reliable, self-optimising, quickly deployable and safe yet efficient in environments shared with humans. ILIAD will enable the transition to automation of intralogistic services with key stakeholders from the food distribution sector, where these challenges are particularly pressing. We will develop robotic solutions that can integrate with current warehouse facilities, extending the state of the art to achieve self-deploying fleets of heterogeneous robots in multiple-actor systems; life-long self-optimisation; manipulation from a mobile platform; efficient and safe operation in environments shared with humans; and efficient fleet management with formal guarantees. Scientifically, ILIAD pursues ambitious goals for complex cognitive systems in human environments beyond a specific use-case. We will overcome limitations in the state of the art in tracking and analysing humans; quantifying map quality and predicting future states depending on activity patterns inferred from long-term observations; planning of socially normative movements using learned human models; integration of task allocation, coordination and motion planning for heterogeneous robot fleets; and systematically studying human safety in mixed environments, providing a foundation for future safety standards. Our consortium is uniquely placed to tackle these challenges and to maximise exploitation beyond the project’s duration. It includes partners with a proven track record in all key research areas, leading technology providers for intralogistics, end users that are leading in their respective markets, and the National Centre for Food Manufacturing at partner UoL, facilitating access to realistic test sites. This mix of partners will ensure a very high impact of the project results.
Air Traffic Management for environment (ATM4E)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Germany,Germany,France,Netherlands,United Kingdom,United Kingdom
Call: Environment and Meteorology in ATM (H2020-SESAR-2015-1, 2015)
Start date: 2016-05-01
End date: 2018-04-30
Duration (months): 24.0
Total project cost (EUR): 599625.0
EU funding (EUR): 599625.0
Participants: 6
Project status: CLOSED

The overall aim of ATM4E is to explore the scope for the potential reduction of air traffic environmental impacts in European airspace on climate, air quality, and noise through optimization of air traffic operations The project will integrate existing methodologies for assessment of the environmental impact of aviation, in order to evaluate the feasibility of environmentally-optimized flight operations to the European ATM network, including climate, air quality, and noise impacts. A preliminary modelling concept for climate-optimization has previously been developed for an FP7 European Project, (REACT4C). The ‘case-study’ approach of REACT4C will be built upon and extended to a multi-dimensional environmental impact assessment, to cover climate, air quality and noise, to better understand impacts in the European airspace. Different traffic scenarios (present-day and future) will be analysed to understand the extent to which environmentally-optimized flights based on multi-dimensional environmental criteria (assessment) would lead to changes in air traffic flows and create challenges for ATM. The findings of the project will be used to prepare a roadmap that is consistent with SESAR2020 principles and objectives, which would consider the necessary steps and actions that would need to be taken to ultimately introduce environmentally-optimized flight operations in European airspace.

Keywords: environment,emissions,climate impact,sustainable,conceptual framework
Disruptive design innovation for safe and lower cost implementation of the alternative to the ozone-depleting gases in the heat pump heating and cooling systems (PropSafe)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Serbia
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-06-01
End date: 2017-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Heat pumps are most energy efficient and least polluting systems for heating, cooling and drying. However, HFC gases used in heat pumps contribute to global warming by trapping heat radiating off the Earth. Global negotiations to eliminate them have concluded only in October 2016 in Kigali. 150 nations agreed to stop selling new HFC based equipment from 2019. Global challenge is to find a suitable replacement for HFC by 2019. R290 is most suitable replacement gas for home and light commercial use as it can be used in the existing, most common, R22 mechanical equipment. However, being flammable at 470C it requires spark-proof electrical components that increase costs by about 30%. Alfa Klima has innovated the design of R290 heat pump systems (PropSafe) so that they do not require spark-proof components. Offering safer alternative at 30% lower cost is a significant added value and it gives Alfa Klima design a first mover advantage in both new installations and R22 replacement. Alfa Klima has been manufacturing heat pump based systems for heating, cooling and drying for the past 20 years. Alfa Klima team has an outstanding engineering and commercial experience and a proven track record in successfully commercializing innovations in the HVAC field.

Keywords: carbon credits,ozone,heat pump,r290
GUst generators and model DesiGn for transonic wind tunnel tEsTs (GUDGET)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Italy,Italy,Germany,France,France
Call: Innovative test rig for the investigation of gust loads in transonic flow conditions (H2020-CS2-CFP08-2018-01, 2018)
Start date: 2019-03-01
End date: 2023-02-28
Duration (months): 48.0
Total project cost (EUR): 1216875.0
EU funding (EUR): 1216875.0
Participants: 5
Project status: SIGNED

GUDGET answers the CfP JTI-CS2-2018-CfP08-AIR-01-38 and aims at providing an innovative experimental set-up for the investigation of gust loads, to be installed in the transonic facility ONERA S3Ch. The proposal GUDGET will design, manufacture, calibrate, verify and finally install in the ONERA S3Ch WT an enhanced gust generator system and an aeroelastic half-model connected to the WT side wall, with the purpose to support the TM in the execution of a WT test campaign and gather information on the aeroelastic behaviour of the model under high amplitude gust conditions, with the acquisition of a relevant database which will allow to assess the numerical capabilities to predict gust loads. The WT test campaign is outside the scope of the GUDGET project. At this aim, the consortium GUDGET has to perform the design of the experimental setup: design and manufacture the WT model according to technical requirements provided by the TM. Special care will be dedicated to the dynamic characteristics of the final model and that a specific interface with the WT will be implemented. In parallel, the consortium will perform a preliminary trade-off analysis to find the best configuration of the GG to comply with requirements dictated in the topic, by considering innovative configurations of tilting airfoils moved by mechanical actuators as well as blowing slots fed by fluidic actuators or a combination of both. The best solution over a number of candidates will be chosen as the one to be designed in detail and then manufactured, calibrated/ verified and eventually installed in the WT. The GUDGET consortium has been setup by joining well recognized and very experienced companies and universities: IBK and POLIMI with a strong experience in the design, manufacturing and operating of WT models; DREAM for supporting CFD and numerical analysis; AVDES for the manufacturing activities and CTEC for the design and implementation of actuation devices.

Keywords: gust generator,wind tunnel,aeroelastic model,gust loads
The online platform for Identity Verification that gives back personal data ownership to the citizens (VerifiedID)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Denmark
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-11-01
End date: 2019-03-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Currently, the management of consumers’ personal data is a complex process particularly for the financial sector, which must ensure to hold accurate, verified and updated data to comply with the Know Your Customer (KYC) and Anti-Money Laundering (AML) regulations. This complexity is present all throughout the relationship with consumers, starting with heavy, costly and time-consuming onboarding processes. Moreover, the EU General Data Protection Regulation (GDPR) imposes new rules on businesses that store customers’ data, stipulating that they must have unambiguous customers’ consent before sharing or processing their data, which protects EU citizens data privacy and reshapes the way that organizations approach data security and privacy. Non-compliant organisations can expect fines of up to €20 million or 4% of annual global turnover. Thus, there is an urgent need for solutions that simply customer onboarding workflow and make easy to obtain consumers’ consent for data processing. NewBanking Identity centralises the EU GDPR, KYC and AML compliance, fitting the needs of banks and other regulated services as investment funds, insurers and real estate. Our identity verification platform allows consumers to complete onboarding processes for signing up to banks with only a few clicks (less than 1 minute) while also providing control and transparency over how their personal data is used, allowing to grant access to the data and revoke it when data access is no longer required (e.g. once the contract expires). The successful implementation of the innovation project is expected to boost the company’s growth, placing NewBanking in a strong position to generate over 33 million EUR in accumulated turnover and close to 17 million EUR in gross profit, 3 years post-project.

Keywords: blockchain,know your customer kyc,anti money laundering aml
Exploring the underlying mechanIsms of partial leptin reduction towards a non-invasive obesity therapy (MILER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Norway,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-04-01
End date: 2025-03-31
Duration (months): 36.0
Total project cost (EUR): 284345.28
EU funding (EUR): 284345.28
Participants: 2
Project status: SIGNED

Leptin regulates energy balance by functioning as a “satiety signal”. When identified 26 years ago, expectations were high that leptin therapies could be used for the treatment of obesity. In contrast to the successful use of leptin for treatment of individuals with lipodystrophy and complete leptin deficiency, pharmacological approaches using leptin therapy for the treatment of diet-induced obesity have been widely unsuccessful. Injecting recombinant leptin in the context of obesity, associated with elevated leptin levels, remains ineffective as central neurons become leptin resistant. Interestingly, Scherer et al. recently published a series of findings that encourages for a conceptual shift. They reported that a partial reduction of circulating leptin levels in the obese state prompts an unexpected systemic response resulting in weight loss, reduced food intake, improved glucose and insulin tolerance and increased energy expenditure - all consistent with leptin re-sensitization in central neurons. The systemic physiological benefits of partial leptin reduction have already been demonstrated. The overall goal of this proposal is therefore to determine the underlying molecular mechanisms that are induced by leptin reduction and trigger leptin re-sensitization. Understanding of these conceptual steps should lead us to explore partial leptin reduction as a viable avenue for anti-obesity and anti-diabetic therapy in the near future. We aim to determine the peripheral effects of leptin reduction using neutralizing leptin antibodies and advanced mouse genetics. Moreover, we will determine downstream signaling events that are affected in peripheral tissues upon leptin depletion using imaging mass cytometry and transcriptional regulation by single cell RNAseq. Finally, we will also determine whether leptin lowering offers synergistic effects with existing weight loss approaches and whether anti-diabetic interventions rely on leptin lowering independent of weight loss.

Keywords: obesity,leptin,leptin resistance
On Photo-enhanced Transport in Ionically Conducting Solids (OPTICS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: CLOSED

Ionic conducting materials form the basis of solid oxide fuel cells, solid oxide electrolyser cells, and batteries, which form a key component of the EU Energy 2050 long-term strategy. There is a need to develop faster ionic conductors, however progress has been slow. Recently, several studies have demonstrated photo-enhanced iodine-ion diffusion as well as suggested interactions between photons and oxygen-ion defects in oxide materials may be possible. The proposed research plan, OPTICS, aims to address the question: Can changes in ion transport be enhanced in technologically relevant ionically conducting oxides (O-ion, H-ion, and Li-ion) by light illumination? There are challenges in studying these effects using conventional methods. Namely, absorption only occurring at the surface in thick samples, artefacts in conductivity measurements stemming from photocurrents and electrode effects, and difficulties understanding the mechanisms due to the indirect nature of photon-ion interactions. In OPTICS, these challenges will be overcome employing isotopic tracer diffusion measurements on epitaxial thin films carried out in tandem with atomistic and continuum simulations to identify the underlying mechanisms. Combining the Host’s (Prof. Roger De Souza) expertise in tracer diffusion and atomistic modelling with the Applicants experience with optical measurements on epitaxial films, photo-enhanced ionic diffusion will be studied experimentally and computationally in the bulk, at surfaces, and at interfaces of nanostructured materials. Light-enhanced ionic transport has the potential, though OPTICS, to lead to substantial improvements in technologically relevant ionic conductors leading to a new class of photo-ionic fuel cells, electrolysers, and batteries.

Keywords: ionic conductors,tracer diffusion,epitaxial films,nanostructured films,continuum modelling,atomistic,modelling,above band gap radiation,surfaces,interfaces,energy conversion and storage