Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Institutional Theory and Discourse Analysis: an empirical investigation of the rhetoric of Anti Vaccination movement (DISCOURSEVAX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 174167.04
EU funding (EUR): 174167.04
Participants: 1
Project status: CLOSED

DISCOURSEVAX project, by adopting a social constructivism perspective and discourse analysis of both verbal and visual texts (spread through press, media, and academic articles) aims at discovering how discourse maintains and reinforces institutions. By using the debate on vaccination that has been occurring in many European countries, this project is meant to provide both theoretical and empirical contributions to the European strategy. It aims to offer an original and innovative interpretation of this social phenomenon that has been involving organizations, institutions, and citizens. The European Commission, especially through European Commission's Directorate for Health and Food Safety (DG SANTE) aims to improve the health of their citizens and to ensure the accessibility, effectiveness and resilience of their health systems. Thus, a multimodal discourse analysis will be conducted, together with interviews to experts and key players involved in the debate (e.g. leaders of the Anti-Vaccine movement and field experts such as scientists). A second analysis will be conducted in England, at Cass Business School in London (UK) that hosts leading scholars of discourse analysis in organization studies. The research project, which will last 24 months, will mainly be conducted at the Research Institute for Urban Management and Governance in WU Vienna (Austria), under the supervision of Professor Renate E. Meyer, who is one of the most important expert in the research of multimodality, discourse analysis, and institutions. DISCOURSEVAX results will be disseminated and the action communicated with tailored measures to a wide audience, including the academic community, policy makers and the general public.

Keywords: mixed method approach topic modeling,sentiment analysis,correspondence analysis,tropes,verbal and visual texts,multimodality
Identifying Chemical Cues in the Polymer-Mediated Engineering of Microorganisms (PolyBact)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-02-01
End date: 2021-08-01
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Here, we will identify how polymer chemistry and composition affects the microbiology of a model pathogen, Vibrio cholerae. To this end, we will explore the chemical space that mediates bacterial adhesion because this bacteria activates complex signaling networks that regulate its physiology following binding to surfaces and hosts. Three main research objectives are: a) To identify what is the role of charge: Electrostatic interactions are critical in the initial attachment of bacteria to hosts and surfaces. Here we will explore how cationic polymers with different degrees of protonation under model conditions affect the behaviour of V. cholerae b) To identify what is the role of hydrophobicity: Early stages of adhesion to hosts and surfaces are also mediated by hydrophobic interactions. Here, we will evaluate a series of cationic polymers carrying similar degrees of protonation but different hydrophobicities. c) To identify the role of selective binding: We will prepare polymers carrying mannose and N-acetylglucosamine, carbohydrates that are involved in the selective binding of V. cholerae to hosts. To achieve these research objectives, we will use a modular strategy that relies on the controlled synthesis of a poly(acryloyl hydrazide) scaffold, its post-polymerisation functionalisation under aqueous conditions, and the in-situ evaluation of activity using phenotypic and transcriptional assays (Part B, Section 1.1.1). We will focus on identifying how non-toxic polymers affect three critical responses in V. cholerae. 1) Clustering and motility; 2) Biofilm formation and maturation, and 3) Virulence and toxicity against a model of the human gut. The main scientific challenge lies in developing new knowledge of how polymer chemistry affects microbial physiology and behaviour, and this knowledge should underpin the future development of new polymers for antimicrobial therapy and microbial biotechnology, research priorities of the European Commission

Keywords: polymer synthesis,post polymerisation modification,microbiology
Researchers without borders (MCD 2017)

Framework: Horizon 2020 — Science with and for Society
Programme: Make scientific and technological careers attractive to young students, and forster sustainable interaction between schools, research institutions, industry and civil society organisations
Action type: Coordination and support actions
Countries involved: Italy,Germany,France
Call: ERA Mobility and Career Day (H2020-SwafS-2016-1, 2016)
Start date: 2017-04-01
End date: 2018-07-31
Duration (months): 16.0
Total project cost (EUR): 109700.0
EU funding (EUR): 87760.0
Participants: 3
Project status: CLOSED

Up to now, there were no national events dedicated to researchers’ mobility and career development at the same time. Researchers are missing concrete information on how to get funded for a postdoc in Europe or where and how they can apply for a position. Our two-day-event in Paris will address these needs by providing information, advice, resources and tools to help researchers to define and implement their job search strategy in Europe. Because networking is the main success factor for the career development, the event will provide a nice opportunity to connect with experts and employers, from academic and industrial sectors. Designed as European mobility and career fair, the event will be split into four main parts: plenary sessions, career fair with exhibitors, thematic workshops where some topics can be deepened and individual counselling sessions with career advisors from across Europe. The event is open to students interested in embarking on scientific careers, doctoral candidates and doctorate holders who want to work abroad. More than welcome are also all the people in charge of guiding international and national researchers in their career development: by assisting at the event, they will have a better overview of the professional opportunities in Europe.

Keywords: mobility,career development,researchers,networking,funding schemes,professional opportunities,career options,employers,academia,industry,europe,interdisciplinary,crossborder
On-Chip Cytometry Printed On Demand (CyPod)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-03-01
End date: 2017-08-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Cytometry (the characterisation and counting of cells) is essential to clinical diagnostics, biotechnology, food industry, water monitoring and many fields of research. Within the ERC Starting Grant, InstantCount, inkjet printing methods have been developed, which allow us to fabricate cell counting chambers with on-chip sample preparation, simplifying cell counting procedures tremendously. By effectively eliminating all sample preparation steps and efficient usage of reagents CyPod promises low-cost, simple, rapid cell counting, including mobile applications. The fabrication by inkjet printing enables us to offer tailor-made solutions. We expect that CyPod tests can replace expensive and complex instruments in many existing cell counting applications, as well as open new markets, e.g. in agriculture and food industry. This project aims at evaluating and enhancing the competitiveness of CyPod cell counting technology by analysing the market, comparing CyPod with potential competitors and adapting our concept to identified customers’ needs. A product demonstration for potential customers and partners will be prepared and the optimal business strategy will be selected for which a business plan will be devised.

Keywords: cytometry,inkjet printing,microfluidics
Senescence as a key factor in leukemogenesis and bone marrow homeostasis in aging (SENAGE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-09-01
End date: 2023-12-21
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: SIGNED

Cancer is a major public health problem and one of the leading causes of death worldwide. In particular, it has been the second cause of death in Spain, Europe and United States. Although cancer can occur at any age, aging is one of the main risk factors for its development. Aging is a complex scarcely understood multi-step process associated with the gradual functional decline of organs and systems. In addition, age-dependent changes in epigenetic regulation occur, indicating that epigenetic regulation may also play an important role in aging. Similar changes have been observed at the cellular level in a mechanism known as senescence. This mechanism is a cellular response that limits the proliferation of aged or damaged cells, behaving as a tumor suppressor mechanism and transformation events lead to escape from it. Chronic lymphocytic leukemia and acute myeloid leukemia are the most frequent types of leukemias and have median ages at diagnosis of 68 years. Both have a low incidence in the young population and increase with age. Thus, it is important to explore novel approaches to understand the mechanisms of aging favoring these types of leukemias, thereby unraveling new target molecules for treatment and prevention. We propose to explore the senescence epigenetic profile in leukemic cells, the impact of senolytic drugs in patients and in the development of AML in spontaneous animal model. The approach will bridge cancer epigenetics with senescence, aging and leukemogenesis. This proposal will augment my scientific knowledge and practical skills. In addition, the complementary planned activities of the action will provide me to the additional tools to become an independent investigator in the near future.

Keywords: senescence,leukemogenesis,hematopoiesis
Embodiment, Intersubjectivity, and the Minimal Self (MinimalSelf)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-07-01
End date: 2018-06-30
Duration (months): 24.0
Total project cost (EUR): 166156.8
EU funding (EUR): 166156.8
Participants: 1
Project status: CLOSED

The proposed project is a philosophical and interdisciplinary study of the most fundamental sense of self. It will take, as its starting point, the concept of “minimal self”, as recently employed by philosophers such as Gallagher and Zahavi. The aim of the project is to develop a clearer, more elaborate, and substantially revised conception of minimal self. First of all, I will engage in depth with relevant phenomenological scholarship, focusing on the work of Husserl and Merleau-Ponty. I will then use the results of this engagement to critically discuss, elaborate and revise current conceptions of minimal self. Finally, I will examine applications of the concept of “minimal self” in psychiatry and psychopathology, for instance by Parnas et al. and Sass. The project will be structured around three guiding questions, to which others have given conflicting or insufficiently clear answers: 1. Is the minimal self given in experience, or is it a formal abstraction from experience? 2. Is the minimal self prior to intersubjectivity, or is it inextricably intertwined with intersubjectivity? 3. In what sense is the minimal self 'embodied', and how does this relate to the issue of intersubjectivity? I will argue that the minimal self is integral to experience rather than an abstraction from it. Furthermore, it is inextricable from interpersonal experience, to an extent that others, such as Zahavi (2014), have not sufficiently acknowledged. I will also make clear how the intersubjective structure of minimal self relates to its bodily nature. This view will be supported through a detailed study of the phenomenology of self-disturbances such as schizophrenia, and I will show how the revised concept of minimal self has significant implications for our understanding of psychopathological disturbances.

Keywords: self,intersubjectivity,embodiment,phenomenology,psychiatry,psychopathology,schizophrenia,experience,cognition,cognitive science
The first on-site mobile solution for complete synthetic grass recycling and materials reuse (ARENA)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Estonia
Call: Boosting the potential of small businesses in the areas of climate action, environment, resource efficiency and raw materials (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-07-01
End date: 2018-06-30
Duration (months): 24.0
Total project cost (EUR): 2527383.75
EU funding (EUR): 1619887.5
Participants: 1
Project status: CLOSED

Boom in synthetic grass sporting fields in EU and USA in the last 15-years has led to huge environmental problem. 600 000 tonnes of rubber, sand and plastics mixed wastes are generated from used fields each year in EU alone. Based on the current market trends, the total wastes will increase by 5-times by 2030, leading to over 3 million tonnes of mixed wastes annually. Despite the growing popularity of synthetic grass both in major football leagues and school grounds, there are no unified regulations or effective technologies for its sustainable EOL management. Current solutions enable only limited used grass recycling and materials reclaim and thus field owners currently landfill 90% of the used grass without any recycling. ASIE, company with over 20-years of experience in synthetic grass fields, has developed the first on-site recycling solution that enables complete used synthetic grass recycling and materials reuse for environmental and economic sustainability. Compared to alternatives, we ensure: • Used grass and infill high-quality re-installation • 100% infill reclaim, separation, cleaning and sanitary treatment • 4x faster old turf removal and 2x faster full field renewal • 50% cost reduction of old field utilization and 50% savings from new installation We aim to achieve a zero-waste concept and improve the environmental sustainability of synthetic grass installations. Our unique ARENA concept enables to eliminate current landfilling and reuse 100% of the materials in new fields or as recycled raw materials in other industries. As a result, we: • Prevent 1 million tonnes of mixed wastes from landfilling annually • Reduce field renewal transportation need by 10-times, leading to 95% less CO2 emissions Our total targeted market in Europe is €350m annually, with very high growth potential in the next years. As a result of the innovation project, we will generate €125m total sales revenue and create 350 new jobs by 2023.

Keywords: synthetic grass,artificial grass,recycling,reuse,eol management
INSIGHT FOR EYESIGHT – Novel mRNA medicines for eye disease (INSIGHT EU)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Netherlands
Call: European SME innovation Associate - pilot (H2020-INNOSUP-2019-02, 2019)
Start date: 2019-12-31
End date: 2021-02-27
Duration (months): 14.0
Total project cost (EUR): 75937.5
EU funding (EUR): 75937.5
Participants: 1
Project status: CLOSED

Proper eyesight is essential for nearly all aspects of our life. Yet, over 4 million people suffer from reduced eyesight or blindness worldwide each year (30 million blind or partially sighted in EU, 1 in 3 senior (65+) EU citizens faces sight loss). Common reasons include glaucoma, cataract, macular degeneration, diabetic retinopathy, corneal injury and inflammation, as well as complications of surgery of the eye and physical injury. Despite continuous improvements in treatment of various underlying causes, much is still to be gained in the promotion of healing of damaged eye tissue. While the patient suffers pain, loss of quality of life and participation in society, socio-economic costs include increased reliance on care-takers, increased healthcare cost and burden. Overall, the societal cost of eye disease is estimated to around 200 €Bn for the developed world. We envision the development of novel drug candidates, based on Mercurna’s proprietary messenger RNA (mRNA)-delivery platform, for greatly improved treatment of eye disease. A particularly interesting opportunity to explore in this project, is the use of mRNA to accelerate healing of the eye, a strategy that is applicable to multiple causes of eye disease. For this project, we aim to hire a researcher with a skillset and knowledge in the field of ophthalmology, who can critically strengthen Mercurna’s Innovation potential in this area.

Keywords: eye disease,mrna,mrna therapeutics,mrna therapy,nanoparticles,nanomedicine,blindness
CAMART2 (CAMART2)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Specific Grant agreement
Countries involved: Sweden,Sweden,Latvia
Call: Teaming (H2020-WIDESPREAD-2014-1, 2014)
Start date: 2015-06-01
End date: 2016-05-31
Duration (months): 12.0
Total project cost (EUR): 497500.0
EU funding (EUR): 497500.0
Participants: 4
Project status: CLOSED

The proposed project CAMART2 is aimed to upgrade the existing “Excellence Centre of Advanced Material Research and Technology at the Institute of Solid State Physics University of Latvia” (CAMART:ISSP) to a new significantly stronger Centre of Excellence. The upgrade will enable efficient transfer of new materials and technologies into products for commercial and public benefits based on exchange of knowledge and synergy with innovation-intensive Consortium partners – KTH Royal Institute of Technology and Acreo Swedish ICT. The partners are worldwide-recognized leaders in research and innovation having pursued a number of successful commercialization projects and are parts of the innovation system in Stockholm, Kista. Specialization of CAMART:ISSP is defined according to RIS3 topic of Latvia “Smart materials, technology and engineering systems” and EC defined KETs – Advanced Materials, Photonics, Nanotechnology and Micro- and Nanoelectronics. The R&D&I activities at the Centre of Excellence will be focused on: 1) Thin films and coating technologies; 2) Functional materials for electronics and photonics; 3) Nanotechnology, nanocomposites and ceramics; 4) Computational material science by atomistic scale modelling of technologically important materials and devices. The implementation of CAMART2 will increase the level of commercialisation of research in Latvia and Baltic Sea region, enhance cooperation between business and academics paving way for innovation-based economic growth, diminishing the disparities between Latvia and well-performing Member States.

Keywords: materials science,innovation,industry,advanced materials,photonics,nanotechnology,micro and nanoelectronics
Perceptual learning as optimized decoding: from maps to mechanisms (DecodePL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 2
Project status: CLOSED

We usually think that as we emerge from childhood, our brains become less plastic, making learning effortful and highly specific. Recent findings however challenge this view, suggesting that even adult perceptual learning (PL), often considered the most specific form of learning, has the potential to generalize across training conditions. This questions classical theories positing that PL changes encoding in early sensory areas, as the functional properties of these areas cannot account for generalization. Building on recent computational models, I propose instead that PL relates to decoding, that is, how information from sensory areas is communicated and read out by higher areas to make decisions, because readout weights can be more flexibly adjusted and accommodate generalization. Decoding accounts are theoretically attractive yet technically challenging to test, as they require a multiscale brain investigation, i.e., tracking PL across networks, areas, and single neurons. I will address these theoretical and technical challenges by capitalizing on a recent innovation combining noninvasive neuroimaging with electrophysiological recordings while monkeys learn a discrimination task. This approach will allow for the first time to create a comprehensive map of brain areas involved in PL in monkeys, determine the involvement of connectivity changes to PL, and unravel the computations that the neurons in these specific areas perform. This project, at the intersection of neuroscience, psychology and computational theory, will set forth the foundations for a mechanistic investigation of PL at an unprecedented level of detail, bridging multiple scales from whole-brain networks down to single neurons, and will therefore allow me to start a competitive scientific career as an independent researcher. Ultimately, this innovative framework will help us understand the building blocks of adult brain plasticity, and how to optimize rehabilitation and educational applications.

Keywords: perceptual learning,macaque monkey,fmri guided electrophysiology,decoding,decision making