Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Microbial ecosystems biology in the human gut (MICROECO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative B iology : from Genes and Genomes to S ystems
Panel description: For all organis ms: Genetics, epigenetics, genomics  and other ‘omics studies , bioinformatics, systems biology , genetic diseases , gene editing, innovative methods and modelling,  ‘omics for personalised  medicine
Countries involved: Finland
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 1485413.0
EU funding (EUR): 1485413.0
Participants: 1
Project status: SIGNED

The gut microbiota has wide-ranging effects on host health and represents a promising target for therapeutic manipulation, particularly in early life. Imbalances in the gut microbiota precede the dThe gut microbiota has wide-ranging effects on host health and represents a promising target for therapeutic manipulation, particularly in early life. Imbalances in the gut microbiota precede the development of conditions such as overweight and immunological diseases, which exert a significant burden on society and on individuals. Early identification and treatment of gut microbiota imbalance in childhood thus offers great potential in combatting these problems, and will become an important part of health care in the future. However, achieving this goal will require a high-level understanding of the processes that regulate the microbial populations. Currently our knowledge of the principles governing gut microbiota responses to treatments is insufficient for reliable and targeted microbiota modification. I hypothesize that conceptual limitations are a significant reason for the current inability to reliably predict microbiota responses to treatments and to modify the microbiota. In this interdisciplinary project, based on daily multiomic time series of child gut microbiota and diet and health diaries, I integrate the theoretical and analytical framework of population ecology, novel next-generation metagenomics-based high-resolution quantitative microbiota profiling, and genome-scale metabolic reconstructions into an ecosystem model of the child gut microbiota. The result will be an unprecedented level of understanding of how the gut microbes interact and respond to external forces. The concept can be applied widely to study the numeric and functional microbiota responses to any treatment and to design targeted interventions based on the predicted responses. The project represents the important next step in microbiota research from description to mechanistic understanding.

Keywords: human gut microbiota,metagenomics,biotic interactions,ecosystem ecology
INDIVIDUAL MOTIVATIONS AND COLLECTIVE RESPONSES TO GIG WORK AMONG MEDICAL DOCTORS (MD GIG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 226751.04
EU funding (EUR): 226751.04
Participants: 1
Project status: CLOSED

MD GIG examines the transition to digital service provision in the public services by exploring the rise of the "online doctor" that provide consultations between doctor-patient via app-based mobile phone technology. The aim is to explore digitalization of healthcare from a worker perspective to highlight the preconditions that give rise to gig work in the healthcare sector and explore the potential consequences at different scales. Whereas before all patients had go to a primary care center on appointment during office hours, today patients can have a consult with a doctor on-demand at any time and from anywhere. Medical work's entry into the platform economy, where work is reshaped into "gigs" that workers perform where and when they want, is developing parallel to organizational and economic restructuring of the healthcare system towards more marketization and private-public partnerships. The project sets out to understand the individual motivations for doctors to take up work in digital doctor platforms through in-depth interviews to produce narratives based in the MDs own experiences, to explore the approach of the trade unions and medical associations to digital doctor platforms through expert-interviews with high level union employees to document their hopes, fears and strategies regarding changing labour markets and working conditions, and to analyse the role of digital doctor platforms in public healthcare restructuring to produce a political economy of digital healthcare in Europe.

Keywords: digital service provision digital health work platform economy work organization labour and globalization feminist geography
Spin polarization in non equilibrated relativistic plasmas (SPINNERET)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 1
Project status: SIGNED

This project addresses non-equilibrium effects and equilibration in relativistic plasmas focusing on spin physics. I will use techniques from quantum-relativistic statistical mechanics, quantum field theory, and many-body theory to answer some of the most pressing questions concerning spin polarization in the quark-gluon plasma (QGP). The QGP is created in laboratories such as the “Large Hadron Collider” and the “Relativistic Heavy Ion Collider” by smashing heavy ions at relativistic speed. It is a state of matter well described by relativistic hydrodynamics where quarks and gluons are no longer confined inside nuclei, and it is the hottest and least viscous fluid in nature. Due to the initial orbital angular momentum, non-central collisions create a rotating QGP, which is the most vortical fluid ever observed. Vorticity couples to the spin of particles, aligning it with the total angular momentum and producing a spin polarization that is measured experimentally. This effect connects the macroscopic motion of the plasma to a microscopic and entirely quantum property such as spin. Recently, another source of polarization has been found in the “thermal shear flow”, which is only present in out-of-equilibrium fluids. Indeed, only the thermal vorticity can be present in equilibrium, and the thermal shear is zero. Studying spin in out-of-equilibrium systems requires tackling some important theoretical questions. The coupling of spin to shear is surprising compared to its coupling to vorticity: how does it happen? The results of any spin calculation depend on the phenomenological definition of a spin density of the fluid: can such a density be fixed microscopically? Finally, any out-of-equilibrium state should relax to equilibrium: how does the relaxation to a vortical equilibrium state happen for a relativistic plasma? These questions will be addressed in my project, SPINNERET.

Keywords: spin polarization in heavy ion collisions,quark gluon plasma,relativistic statistical mechanics,eigenstate thermalization hypothesis,relativistic hydrodynamics
Using synthetic lethality to identify functional genetic Relationships in microAlgae: The next step For systemAtic gEnetic interactions anaLysis in Chlamydomonas reinhardtii (RAFAEL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Czechia
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 207758.16
EU funding (EUR): 207758.16
Participants: 1
Project status: SIGNED

Genetic interactions describe the phenotypic consequences of variations in a specific gene, whether genetically or environmentally induced, associated with other gene. Discovering synthetic genetic interactions is crucial for unraveling the complexity of metabolic pathways and cellular functions, offering deeper insights into how cells operate under stress. Traditional genetic studies in C. reinhardtii have often focused on individual gene mutations, without fully exploiting its sexual reproduction capabilities to generate double mutants. This project aims to bring a new perspective to the study of gene functions in C. reinhardtii by identifying synthetic genetic interactions among nutrient metabolism genes. Through an innovative interdisciplinary approach involving the use of available single mutant strains from Chlamydomonas Library Project (CLiP) collection, established genetic tools, and the generation of haploid double mutants via crossing, this project seeks to uncover complex interactions between metabolic pathways. By serving as a foundation for future large-scale synthetic interaction studies, this project goes beyond current methodologies in studying genetic functions in C. reinhardtii, impacting the research field of metabolic regulation in photosynthetic organisms. The RAFAEL project will contribute significantly to the fellow’s professional development, equipping him with expertise in algal genetics and expanding his interdisciplinary research scope.

Keywords: chlamydomonas reinhardtii synthetic lethality synthetic sickness genetic interactions epistasis metabolism tor1 pathway
Affordable and sustainable self-powered GLUCOSE sensing system for a global FAIR diabetes management (FAIRGLUCOSE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-05-01
End date: 2023-10-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

FAIRGLUCOSE proposes a low cost, sustainable and self-powered standalone glucose sensing system that relies on the well-known oxidation process of glucose coming from finger prick blood and transfers it to a voltage readout through an innovative and extremely simple strategy. In this way, a measurement that typically requires a potentiostat with a microcontroller and a battery is performed here with a minimalistic and battery-less circuit that fits within the footprint of a commercial glucose strip. This allows for a reduction not only in device cost, but also in the generation of waste of electrical and electronic equipment (WEEE or e-waste), avoiding the cumulative effect of millions of tests and their corresponding batteries performed at remote sites away from adequate recycling infrastructures. In order to interpret the result, the strip can be integrated in a card format that translates voltage into level bars accounting for low, normal and high glucose indicators – a solution that would substitute urine strips - or into a more sophisticated but still low-cost card containing a NFC chip allowing the transferring of a numeric result into a cell phone. Both cards could be implemented with state-of-the art flexible electronics technologies and could be reused infinite times, as energy would always come from the sample. The first targeted market of FAIRGLUCOSE solutions is located in low and middle-income countries, where cost of current glucometers limits severely the self-monitoring of blood glucose among population. However, at mid-term it is likely that the sustainability and affordability of the approach displaces the current glucose players in some market niches of developed countries and generates new applications in the healthcare and agro-food arena. Thus, FAIRGLUCOSE aims to investigate the commercial feasibility of this disruptive approach and create an innovation roadmap that allows deploying the technology where it can make the most.
ACHIEVING HUMAN-MACHINE COLLABORATION WITH ARTIFICIAL SITUATIONAL AWARENESS (AWARE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (JU-JTI)
Countries involved: Croatia,Austria,Sweden,Hungary,Iceland,Ukraine,Spain,Canada,Switzerland
Call: ATM application-oriented research for Artificial Intelligence (AI) for aviation (HORIZON-SESAR-2023-DES-ER-02, 2023)
Start date: 2024-06-01
End date: 2026-11-30
Duration (months): 30.0
Total project cost (EUR): 1940625.0
EU funding (EUR): 1940625.0
Participants: 9
Project status: SIGNED

The goal of the project is to enable human-machine collaboration by using an artificial situational awareness system which is enabling AI to anticipate and respond to human needs by understanding human intent and goals. While humans are extensively trained to understand the capabilities, limitations, and functionality of the machines they are using, further improvements in human-machine collaboration are currently hindered by lack of awareness of human's intent on the side of machines. The project will develop and test an AI Assistant Application providing adaptable human-centric support to enhance air traffic controller's (ATCO) performance and to reduce ATCO’s workload despite high task complexity. This will be achieved by development of human-machine collaboration environment that relies on recognition of ATCO intent, ATCO situation awareness (compared to machine situation awareness) and ATCO mental load. ATCO's intent will be analysed by tracking their attention and human-machine interactions and comparing them to the tasks that need solving as assessed by the artificial situational awareness system. Adaptable support will then be provided either in solving the task they are currently focused on or solving an unrelated task autonomously. This will allow ATCOs to maintain their skills and expertise while preventing a shift towards supervisory control that has been demonstrated to undermine human capability to take-over in situations with degraded automation. A goal of the adaptable and human-aware system is to maintain ATCOs in an active role, to train their skills and expertise on the job while selectively using higher levels of automation to augment capacity. ATCOs are supported in their tasks rather than substituted by automation. It is expected that ATCOs can handle high-complexity scenarios when assisted by an attention-aware support system. ATCO workload is expected to decrease with the use of support functions.

Keywords: artificial situational awareness,air traffic control,human machine collaboration
Science from Nature to your Table (Sci-NURTURE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: European Researchers' Night
Action type: Coordination and support actions
Countries involved: Türkiye
Call: European Researchers' Night 2022-2023 (HORIZON-MSCA-2022-CITIZENS-01, 2022)
Start date: 2022-04-01
End date: 2023-11-30
Duration (months): 20.0
Total project cost (EUR): 146125.0
EU funding (EUR): 146125.0
Participants: 1
Project status: CLOSED

Science from Nature to your table (Sci-NURTURE) reflects how environmentally sustainable agriculture and food production play an important role in our daily life. We will demonstrate the scientific facts and developments in the human food chains (animal-based, plant-based, and seafood-based) from the very beginning stages in nature through our table. Students, kids, and citizens will go through the story of nature components becoming food on our table by practicing all levels with researchers. This will help increase awareness of the sustainability of natural resources in society. Participants will appreciate the importance of terms such as "sustainability", "water footprint" and "consumed energy". Public awareness for researchers and innovation activities is expected to increase when they become aware of the contribution of scientists in their daily life. The Sci-NURTURE will rely on a wide area of subjects that cover most of the missions and Green Deal issues by practicing and demonstrating those issues to the public. Since the Eastern part of the country is less developed as compared to other regions in the country, science parks and other attraction centers are almost non-existent in the province. The young generation and the kids in the region are eager to see novelties of science and they are longing for any kind of attraction. Having a science-related organization in the city will create huge excitement for the public. By presenting scientific developments in different fields, Sci-NURTURE will provide youth with a path for picking their future profession. Finally, Ataturk University has been a partner of very few EU projects since only a couple of researchers apply for EU funds. There is a hesitation in researchers to go through all steps of getting EU funds. We believe our project will be a bridge not only between society and scientists but also between EU and scientists in the region and it will encourage the researchers to apply for EU funds.

Keywords: public awareness,food chain,natural resources,conscious knowledge,researchers
FABrication of 3D metasurfaces to enable the next generation of high efficiency optical products (FABulous)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Made in Europe (co-programmed)
Countries involved: Spain,France,Germany,Greece,Belgium,United Kingdom
Call: Products with complex functional surfaces (Made in Europe Partnership) (RIA) (HORIZON-CL4-2022-TWIN-TRANSITION-01, 2022)
Start date: 2022-12-01
End date: 2026-11-30
Duration (months): 48.0
Total project cost (EUR): 5475680.0
EU funding (EUR): 5475680.0
Participants: 13
Project status: SIGNED

FABulous will develop an industrial surface ‘coating’ technology that exploits breakthroughs in multiphoton lithography and process modelling to manufacture high resolution 3D metasurfaces at a throughput viable for series production. These metasurfaces will be capable of manipulating light with unprecedented flexibility and will open the possibility of designing and manufacturing smaller, lighter, and more environmentally friendly products, through the replacement of bulky components and/or the chemical coatings currently used to enhance the efficiency and performance of optical products. The project will explore novel methods for rapid (>10cm2/min) micro-fabrication of high-resolution (smaller than 200nm) 3D structures, and the development of new production tools to optimise the design and integration of the metasurfaces into functional products. These innovations will then be scaled for commercial applications and integrated into an industrial platform with a quality assurance and control system, enabling the fabrication of 3D metasurfaces on a range of substrates with unprecedented productivity, resolution, flexibility, and reliability. The application of the technology and its potential to contribute to the design and manufacturing of more sustainable and circular European goods will also be demonstrated in a series of uses cases. The platform will be used to coat optical components (lenses, light pipes, and micro-optics arrays) with custom metasurfaces, and demonstrate that these components, when integrated into the design and manufacturing of functional optical systems (cameras, automotive lights and PV cells), can significantly improve their efficiency whilst in parallel reducing their environmental footprint.

Keywords: metasurface,multiphoton lithography,optics,design technology co optimisation,micro nanopatterning,photonics,laser manufacturing,surface structuring
Cavity Quantum Electro Optics: Microwave photonics with nonclassical states (cQEO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Austria
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1999073.0
EU funding (EUR): 1999073.0
Participants: 1
Project status: SIGNED

Optical photons propagate with ultra-low loss and do not interact easily which makes them perfect information carriers. Logical operations and sensing on the other hand rely on nonlinearities and strong interactions. GHz clock speed electrical circuits are used for computing and wireless receivers – a frequency range where also some of the most promising solid-state quantum devices, such as superconducting circuits and semiconductor spin qubits, operate and interact. The field of microwave photonics combines these two domains of the electromagnetic spectrum with a diverse set of applications ranging from radar and satellite communication, to radio-over-fiber and remote sensing. At the quantum level however, no equivalent technology exists. This is particularly problematic because quantum systems rely on analog information exchange in a low-noise environment. Microwave quantum circuits so far are restricted to operate inside an isolated space at millikelvin temperatures. Building on our modular electro-optic platform - the lowest noise microwave-optical interconnect to date - cQEO will realize a remarkable set of new experiments that were not possible before: Heralded entanglement and teleportation of long-lived qubit states over kilometers of fiber, synthesis of optical cat states from microwave cats, photonic control and readout of superconducting circuits, as well as photonic masing and RF sensing below the standard quantum limit. Pushing towards higher electro-optic cooperativities will open up the rich physics known from cavity optomechanics, except now it is the readily accessible microwave field that experiences dynamical and quantum back-action rather than a mechanical mode. This is a new physical limit akin to nonlinear optics that was predicted a decade ago but never realized. cQEO aims to uncover the full range of new physics offered by high quantum cooperativity electro-optics combined with the unique capabilities of circuit quantum electrodynamics.

Keywords: quantum information,quantum communication,quantum sensing,circuit quantum electrodynamics,cavity electro optics,superconducting qubits,fiber optic communication