Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Ultra-High Field Magnetic Resonance Imaging (HIMR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany,Netherlands,Germany,Germany,United Kingdom,Italy,Netherlands
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-11-01
End date: 2016-10-31
Duration (months): 48.0
Total project cost (EUR): 3597440.0
EU funding (EUR): 3597440.0
Participants: 8
Project status: CLOSED

The High field Magnetic Resonance (HiMR) Initial Training Network aims to train the future leaders of academic and industrial research in the fundamental science and novel applications of ultra-high field (UHF) in vivo magnetic resonance (MR), in order to address an increasing and currently unmet demand from academia and industry for such specialists. The highly complex and multi-faceted nature of UHF MR means that excellent training can only be provided by immersing ESRs in an environment that integrates different research areas, sectors and groups. The HiMR ITN is centred on a cutting edge, multidisciplinary research program that exploits the complementarities of the participants. This research programme is organised into four themes each focused on a crucial area of development of UHF. The first focuses on improved structural imaging, advancing our understanding of the origins of contrast in MRI scans and developing non-invasive biomarkers for multiple sclerosis. The second theme is centred upon exploiting UHF to develop ultra-high resolution functional MRI (fMRI) which will be very important in basic neuroscience research. It also aims to make fMRI more quantitative, thus encouraging its uptake in the clinic. The third theme aims to exploit the enhanced sensitivity of MR spectroscopy (MRS) at UHF in developing highly specific biomarkers. The final theme will develop novel hardware for both research and in the clinic, and methods of monitoring and correcting motion which limits in-vivo MR resolution. Finally the HiMR ITN will provide a unique opportunity to measure safety outcomes over a large group of workers. The proposed interdisciplinary and intersectoral training program, embedded in this research program, will provide a platform for training ESRs to become specialists in UHF MR, whilst also furnishing them with experience of a broad range of work environments, experimental techniques and theoretical knowledge relevant to the full range of in vivo MR.

Keywords: p320 medical physics,p219 biophysics,l214 biological systems analysis - modeling and simulation,l510 neuroimaging and computational neuroscience
RADical reduction of OXidative stress in cardiovascular diseases (RADOX)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,United Kingdom,United Kingdom,United Kingdom,Belgium,Italy,Spain,Netherlands
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 3935721.0
EU funding (EUR): 3935721.0
Participants: 9
Project status: CLOSED

Cardiovascular disease (CVD) constitutes a major and increasing health burden in developed countries. The prediction is that the prevalence of these conditions will increase by ~60% over the next 20 years. Therefore, the development of novel treatments for patients with CVD becomes more and more urgent. Oxidative stress is an important molecular contributor to the pathogenesis of CVD. However, oxidative stress-related therapeutic strategies are still missing. This ITN consortium links investigators highly active in the field of oxidative stress-signalling, and will strongly enhance collaborative research and integrate complementary interests to obtain innovative science and outstanding in-depth integrative multidisciplinary training possibilities. The scientific aims of this ITN proposal entitled ‘RADical reduction of OXidative stress in cardiovascular disease (RADOX)’ are to characterize the specific sources of reactive oxygen species (ROS) and their interaction in CVD and to use this knowledge to develop diagnostic tools for the detection and quantification of ROS and their subcellular targets. This will lead to new therapeutic strategies which modulate the activity of these specific sources of ROS. This RADOX consortium, containing 9 full partners (7 academic and 2 private) and 7 associate partners (1 academic and 6 private) will train 11ESR and 4ER. The mission of this ITN consortium is to create in a period of 4-years the future leaders in this field. Our trainees will receive unequaled multidisciplinary scientific and transferable skills training which will make them ready for leading positions in academia or industry. The training in this programme will be at 3 levels i.e. through research under supervision, transferable skills and secondments and will have a strong intersectoral, international and interdisciplinary character. Afterwards, the RADOX structure will serve as a European platform for outstanding doctoral training and oxidative stress research.

Keywords: cardiovascular disease,oxidative stress,nitric oxide synthase (nos),reactive oxygen species (ros),free radicals,superoxide,myocardium,atrium,vasculature
Language and Perception (LANPERCEPT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Norway,Germany,Germany,Spain,Netherlands,Denmark,United Kingdom,Sweden,United Kingdom,Spain
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 4152363.18
EU funding (EUR): 4152363.18
Participants: 10
Project status: CLOSED

This network provides a unique approach to understanding the interaction between two central cognitive systems: language and perception. Traditionally these systems have been studied independently, with training provided from a single discipline perspective. This training network offers an interdisciplinary approach to the examination of the bidirectional relationships between language and perception for the first time, bridging the translational gap between basic and applied research, both in clinical settings and in industry. The workpackages in the training program form three interconnected clusters: (1) "Language-perception interactions in healthy participants - basic research" investigates theories of language and perception from complementary perspectives in order to break new ground in understanding language-perception interactions. (2) "Language-perception interactions in atypical populations – applied research" transports state-of-the-art methods of language-perception to atypical populations in order to identify underlying mechanisms for different kinds of atypical behaviours. (3) "Advanced technologies for language and perception" research bridges basic research and its applications in the development of new behavioural and neurophysiological techniques to identify the interaction between language and perception among typical (adults and children) and atypical populations. Industrial partners within the ITN will work across all three clusters, offering project-specific collaboration with ER and ERS trainees, secondment placements, entrepreneurial training at schools and courses, as well as supervision and industrial guidance through supervisory board and educational committee participation. This ITN will produce a new generation of integrative language and perception scientists with the technological, theoretical, and entrepreneurial skills necessary to make breakthroughs in the understanding of language-perception interactions and associated applications

Keywords: language,perception,typical and atypical development,development of integrative methods
Epigenetic Training Network - Innovative techniques and models to understand epigenetic regulation in the pathogenesis of common diseases (EPITRAIN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Finland,Spain,Sweden,Belgium
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-03-01
End date: 2017-02-28
Duration (months): 48.0
Total project cost (EUR): 3816547.8
EU funding (EUR): 3816547.8
Participants: 6
Project status: CLOSED

Despite the past century witnessing considerable advances in our understanding of genetics, the success of genome-wide association studies (GWAS) in detecting putative causal variants has been tinged with disappointment as the effects found have been modest. Epigenetics promises a novel biological foundation of a new way of looking at common diseases because it responds to the environment and governs gene expression - thus potentially mediating a path from environmental effects to gene expression to behavior. The primary objective of the EpiTrain Research Training Network is to promote integrative training-through-research in the field of epigenetics, especially of young researchers, both pre- and post-doctoral level, within the frame of high quality international collaborations. By integrating academic and private institutions with specializations in technological, analytical and computational aspects of epigenetic research, the training program will not only provide insights into research techniques and paradigms complementary to the individual projects, but will also strengthen professional skills and enhance the career prospects of the fellows.

Keywords: epigenetics,epigenomics,epidemiology,cancer,dna,methylation,epigenetics and gene regulation,genetic epidemiology
Insect Timing (INSECTIME)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Netherlands,Germany,United Kingdom,France,Italy,Czechia,Poland,United Kingdom,United Kingdom
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-04-01
End date: 2017-03-31
Duration (months): 48.0
Total project cost (EUR): 3999988.0
EU funding (EUR): 3999988.0
Participants: 10
Project status: CLOSED

INsecTIME seeks to train the next generation of ESRs in the intellectual, technological, complementary and commercial skills required for future European competitiveness in the area of biological timing, an area with considerable commercial potential. The scientific focus will be on circadian and seasonal rhythms in the model insect, Drosophila, which has proved particularly relevant for understanding temporal aspects of human health and well-being, plus non-model insects such as the parasitoid wasp and olive fruitfly, two species with major economic implications. The work is multidisciplinary, bringing together scientists from academia and the private sector with different skills in neurogenetics, genomics, life history biology, mathematical modelling, biocomputing, biological control, anatomy and population genetics. Through synergistic interactions via secondments to world class research institutions and to applied entomology and biocomputing SMEs, training workshops, and instruction in transferable skills, young researchers will learn the full-range of cutting-edge technical skills allied to an appreciation of the commercial possibilities of their work. Their obligatory secondments to SMEs will include training in the management, organisation and finance of the private sector, and be buttressed by further workshop courses in general bio-commerce, intellectual property, marketing, raising capital etc. They, and their supervisors will contribute to outreach programmes, and the ERSs and ERs will be guided in the development of their own personal career portfolios, with ESRs submitting doctoral theses. Our young researchers will represent the next crop of technically well-trained, but unusually, commercially aware, computer and mathematically literate molecular neurogeneticists, whose versatile skills will enhance pan-European collaborations for years to come.

Keywords: insect,circadian,seasonal,behaviour,diapause,photoperiodicity,environment,evolution,ecology,modelling,genomics,pests,parasitoids,mutagenesis,neurogenetics,software,automation.
iSocial: Decentralized Online Social Networks (ISOCIAL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Sweden,Cyprus,Italy,Greece,Spain,Israel
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2017-03-31
Duration (months): 54.0
Total project cost (EUR): 3738976.01
EU funding (EUR): 3738976.01
Participants: 7
Project status: CLOSED

The rapid proliferation of Online Social Networking (OSN) sites, like Facebook and MySpace, is expected to reshape the Internet’s structure, design, and utility. Industry experts believe that OSNs create a potentially transformational change in consumer behavior and will bring a far-reaching impact on traditional industries of content, media, and communications. Nevertheless, at a European level, there is a recognized shortage of highly skilled researchers, scientists and engineers trained in building IT platforms and service infrastructures capable of hosting innovative OSN services and applications. The iSocial consortium, which consists of 7 full partners and 6 associate partners, envisions the emergence of distributed and scalable overlay networking and distributed storage infrastructures that will provide support for open social networks and for innovative social network applications, preserving end-user privacy and information ownership. The main objective of iSocial is to provide world class training for a next generation of researchers, computer scientists, and Web engineers, emphasizing on a strong combination of advanced understanding in both theoretical and experimental approaches, methodologies and tools that are required to develop Decentralized Online Social Networking platforms. iSocial training network will fund 11 Ph.D. students; 5 post-doctoral fellows for 18 month stays, 2 intensive post-graduate schools, 3 workshops and a final Conference. To meet this goal, iSocial is divided into four interconnected research topics: i)Overlay Infrastructure for Decentralized Online Social Networking Services; ii)Data storage & distribution; iii)Security, privacy & trust,iv) Modelling and Simulation. These topics include important and timely research challenges with a high exploitation potential.

Keywords: g113 parallel and distributed computing,g208 networks,g102 database management,g106 informatics and information systems,g111 modelling tools
OFET biosensors for point-of-care applications (SENSE-OF-CARE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy,Germany
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-12-01
End date: 2016-11-30
Duration (months): 48.0
Total project cost (EUR): 466726.04
EU funding (EUR): 466726.04
Participants: 2
Project status: CLOSED

Electronic, label-free biosensors characterized by rapidity and detection proved to be very promising being able to directly detect biological recognition events without the need of markers. In this respect, organic bioelectronics has gained a huge interest among scientists coming from different disciplines and sectors due to its high impact on medical, clinical, food and environmental fields. Presently Europe holds a leading position in this research area, being almost all the world-leading research groups and industrial companies in this field located in Europe. Realizing the promise of Organic electronic sensors requires research and training in crossing disciplines, such as chemistry, biology, physics, materials science, and electrical engineering. The objective of this project is to strengthen the research in this new and fast developing strategic research field by teaching and training the next generation of scientists on OFET biosensors developments both in the academia and the private sectors. Innovative OFET biosensors for point-of-care application capable of sensitive, selective and reliable detection of analytes of clinical relevance will be developed. The novelty of the proposal is the development of OFET devices that fully integrate biological recognition elements, such as antibodies or other receptors to confer specificity. Specific reactions (i.e. antigen/antibody binding) will be then used for analyte detection. However, not only medical diagnostics but also a wide range of sensing applications (e.g. food monitoring, detection of chemical, biological poisoning agents, etc.) will benefit from these new OFET device configurations.

Keywords: organic electronics,biosensors,point of care
Machine Learning for Personalized Medicine (MLPM2012)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland,Germany,United Kingdom,Belgium,France,Spain,Spain,United States,United Kingdom
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 3758056.9
EU funding (EUR): 3758056.9
Participants: 11
Project status: CLOSED

Over the last decade, enormous progress has been made on recording the health state of an individual patient down to the molecular level of gene activity and genomic information – even sequencing a patient’s genome for less than 1000 dollars is no longer an unrealistic goal. However, the ultimate hope to use all this information for personalized medicine, that is to tailor medical treatment to the needs of an individual, remains largely unfulfilled. To turn the vision of personalized medicine into reality, many methodological problems remain to be solved: there is a lack of methods that allow us to gain a causal understanding of the underlying disease mechanisms, including gene-gene and gene-environment interactions. Similarly, there is an urgent need for integration of the heterogeneous patient data currently available, for improved and robust biomarker discovery for disease diagnosis, prognosis and therapy outcome prediction. The field of machine learning, which tries to detect patterns, rules and statistical dependencies in large datasets, has also witnessed dramatic progress over the last decade and has had a profound impact on the Internet. Amongst others, advanced methods for high-dimensional feature selection, causality inference, and data integration have been developed or are topics of current research. These techniques address many of the key methodological challenges that personalized medicine faces today and keep it from rising to the next level. Despite this rich potential of machine learning in personalized medicine, its impact on data-driven medicine remains low, due to a lack of experts with knowledge in both machine learning and in statistical genetics. Our ITN aims to close this gap by bringing together leading European research institutes in Machine Learning and Statistical Genetics, both from the private and public sector, to train 14 early stage researchers.

Keywords: machine learning,statistical genetics,personalized medicine
Soft Matter at Aqueous Interfaces (SOMATAI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Netherlands,France,Greece,Egypt,Germany,Belgium,Germany,Netherlands,Netherlands,Netherlands,Switzerland
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2016-09-30
Duration (months): 48.0
Total project cost (EUR): 3562776.87
EU funding (EUR): 3562776.87
Participants: 14
Project status: CLOSED

Soft nanotechnology is generally considered as a field that will have a major impact on technological developments in near future. However, the fundamental understanding of the wealth of new structures lacks far behind, despite supporting activity from material science. Such an understanding is indispensable for sustainable growth of this important research domain and its applications. A physics-oriented interdisciplinary education is urgently needed to guide young researchers to the point where they can tackle the relevant fundamental questions. SOMATAI is set up to provide just such training by combining two distinct scientific fields: Soft matter science is a well established interdisciplinary field for the bulk investigation of polymers, colloids, and liquid crystals with response amplitude and time to external stimuli as a function of soft matter structure being of special interest. The second highly relevant field is interface science, since nano-structured materials contain a huge area of internal interfaces which have an essential impact on material properties. The application of the soft matter approach to interfaces promises new and deeper understanding of interfacial phenomena. Interfaces of a water phase to a solid, liquid or gaseous second phase are of special interest and a focal point of SOMATAI. Such interfaces are highly relevant to products from European industry (food, cosmetics, paints) and processes (washing, coating, water purification). They have an outstanding importance from a scientific point of view due to specific interactions at such interfaces. This carefully planned teaching and research programme in a network of 10 leading academic partners, 1 large scale companies, 2 SMEs, and 4 top-level associated partners from Germany, Taiwan and the USA will ensure that young researchers are given an excellent training in a pioneering research domain of high scientific and technological relevance, where Europe can take a leading position.

Keywords: soft matter,interfaces,colloids,polymers,physical chemistry,soft nanotechnology