Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Fabrication of direct bandgap, hyper-doped, thin and strain-tailored GeSn:Sb- and GeSn:Al-on-Ge layers (PORTAL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-11-15
End date: 2026-11-14
Duration (months): 24.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 1
Project status: SIGNED

The objective of the PORTAL project is to fabricate direct bandgap, hyper-doped, thin, and strain-tailored GeSn:Sb- and GeSn:Al-on-Ge layers, with enhanced carrier transport properties and light emission and absorption efficiency. To achieve this goal, a combination of deposition and pulsed-laser melting processes will be used. Taking advantage of the ultrafast liquid to solid phase transition will enable the fabrication of high-quality GeSn alloys, doped with Al or Sb above their respective solid solubility. This process methodology is expected to yield fully relaxed or even tensely strained alloys with residual defects. Such materials could bring a new step forward in photonics, particularly for infra-red optical detectors. To acquire an in-depth understanding of the doped-GeSn alloys properties, an interdisciplinary study will be led by applying different laser and deposition conditions, collecting data from several characterization techniques and running simulations. The final outcome of this project aims to build a complete, reproducible and large-scale transferable process for hyper-doped GeSn materials, that could be integrated in high-performance and low-cost devices. In addition to the significant socio-economic impact the PORTAL project is expected to bring, it has been ensured that all possible efforts will be made in favour of environmental considerations. This study will be conducted in a multi-disciplinary research group of the University of Padova under the supervision of Prof. Enrico Napolitani. A two-way transfer of knowledge and savoir-faire between the host organization and the experienced researcher will be favoured by their respective fields of expertise and established collaborations as well as the wide range of equipment provided by the University of Padova. This individual fellowship will enrich the applicant’s management and technical skills and expand his professional network, improving the development of his career.

Keywords: germanium tin,pulse laser melting,doping,strain,band engineering,mobility,gesn sb,gesn al
CUSTOMIZED GAMES AND ROUTES FOR CULTURAL HERITAGE AND ARTS (CULTURATI)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Türkiye,Finland,Italy,United Kingdom,Germany,Spain
Call: Europe’s cultural heritage and arts - promoting our values at home and abroad (HORIZON-CL2-2022-HERITAGE-01, 2022)
Start date: 2023-02-01
End date: 2026-01-31
Duration (months): 36.0
Total project cost (EUR): 2389941.69
EU funding (EUR): 2389941.69
Participants: 15
Project status: SIGNED

Along with the tourism industry, cultural and creative industries (CCIs) are most affected by the pandemic. All CCIs need systems or management tools to make them more resilient today. Thus, CULTURATI aims to build an inclusive cultural-educational ecosystem with visitor and capacity management by using digital solutions and cutting-edge technologies to (1) enhance and support collaboration between CCIs, and citizens to promote Europe’s culture, values, and interests, (2) increase accessibility, awareness, and understanding of cultural heritage and arts, (3) preserve cultural heritage by preventing deterioration due to overcrowding and sustain valuable resources (4) enhance the audience experience through customized games, and routes by optimizing the number of people on the venue or site-based CCIs, ensuring social distancing between them in case of a pandemic. CULTURATI is a global content platform that enables CCIs, creative professionals, and citizens to create content collectively for cultural heritage and arts across Europe. Consequently, CULTURATI curates content in its database and delivers customized information with the help of its algorithm. Therefore, the principal objective of the CULTURATI project is to design, develop, evaluate and validate mainstream technologies for its ecosystem utilizing the Internet of Things, cloud and mobile technologies, sensors (people counters), and Artificial Intelligence. Our user-centered design methodology situates user needs at the center by actively involving them in five pilot sites across Europe to validate CULTURATI, as well as increase engagement with broader audiences. Accordingly, our interdisciplinary consortium involves computer scientists, CCIs, academia from various disciplines, including social sciences, SMEs, public authorities, and non-profit community initiatives to focus on engaging citizens, and ensuring widespread communication and exploitation of CULTURATI in Europe and internationally.

Keywords: iot,ai,algorithm,optimization,global content platform,content curation,ccis,customized games and routes,audience experience
Unravelling the cellular machinery and triggers for autophagy-mediated Nuclear Pore Complex degradation in yeast (QualityNPC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 202125.12
EU funding (EUR): 202125.12
Participants: 1
Project status: SIGNED

The nucleus, surrounded by the nuclear envelope (NE), houses genetic material, and nuclear pore complexes (NPCs) mediate the selective passage of molecules between the nucleus and the cytoplasm. NPCs are critical for cellular functions such as protein synthesis and cell division. Dysfunction of NPCs is associated with ageing and disease, highlighting the importance of quality control mechanisms such as NPC degradation. However, the pathways that control NPC degradation remain largely uncharacterized. A recent study in yeast revealed for the first time a selective autophagy pathway responsible for the degradation of fully assembled NPCs embedded in the NE. NE-derived NPC-containing vesicles are engulfed by an autophagosome through the initial binding of Atg8 to the cytoplasmic-facing Nup159. Although Nup159 is present in all NPCs, NPC degradation occurs rarely under normal conditions and is only upregulated under stress conditions such as starvation, indicating a tightly regulated process. This research, using Saccharomyces cerevisiae as a model, aims to uncover the machinery and triggers that regulate autophagic NPC degradation through two main objectives. First, to identify the machinery required for the formation of NPC-containing vesicles, using a powerful combination of genome-wide screening and structural insights from cryo-electron tomography. Second, to determine the mechanisms that trigger the formation of NPC-containing vesicles, focusing on two likely triggers: NPC clustering and nuclear content. The results of this study will redefine our knowledge of NPC quality control and the autophagic degradation pathway for NPCs. The knowledge gained from processes in yeast can potentially be extended to human cell biology, where NPC integrity is crucial in ageing and disease.

Keywords: autophagy,nuclear pore complex,npc,protein quality control,protein degradation
Early Build-up of Ringed Planet-Forming Disks (EARLYBIRD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-03-01
End date: 2029-02-28
Duration (months): 60.0
Total project cost (EUR): 1999250.0
EU funding (EUR): 1999250.0
Participants: 1
Project status: SIGNED

With one planet per star on average, planet formation must be a robust process. Yet, surprisingly, we still do not fully understand how planet formation works. Current models for planet formation usually assume pre-existing smooth disks and homogeneously distributed planetesimals of arbitrary composition. In contrast, recent results highlight the crucial role of early stage disk sub-structure, inhomogeneous accretion, and carbon depletion processes on the final planetary systems. Until now, adequate techniques to model these dynamic, complex systems in a computationally cost-efficient way were lacking. The overall aim of EARLYBIRD is therefore to overcome this bottleneck and track the planet-building material and its composition through the initial formation of disks into the populations of planetesimals and planets and to reveal in which ways these processes are observable in older disks and exoplanets. The project concretely will 1) determine the global effects of streamers/sustained infall on early evolution of disks and planet formation, 2) study how outbursts and dust evolution interact and determine the effect of high dust-to-gas ratio infall on planetesimal formation, 3) track compositonal changes (e.g. carbon, CO, water) during planet formation and 4) decipher the observable properties all these scenarios imprint in the distribution and composition of small dust, planetesimals, and planets. Based on my pioneering work on disk particle growth and transport, EARLYBIRD will utilize highly innovative 3D modeling techniques, which are unique in being calibrated against full coagulation models and still are two magnitudes faster than a full solver. The project will thereby not only enable me to fully exploit the information imprinted by the disk formation stages on planet formation, but also pave the way for cost-efficient 3D-modeling of dynamic systems in neighboring fields.

Keywords: circumstellar disks planet formation star formation formation of the solar system disk formation circumstellar dust
Categorical, Homological, and Non-commutative methods in Geometry (CHaNGe)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-01
End date: 2027-01-31
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

This proposal is primarily interested in algebraic geometry, a field that underpins geometric intuition with the precision brought about by calculation from algebra. The algebraic information of an algebraic variety - the set of common zeros of polynomial equations – is packaged in sheaves and organized in categories, which makes it possible to study these objects by importing the tools of homological and (non-)commutative algebra. This categorical approach is natural for many of the current leading questions in mirror symmetry, birational geometry, representation theory, and theoretical physics because it serves as a bridge between the geometric and algebraic language. It is also fundamental, as many properties and even classification results are not possible without it. The proposal is deeply interdisciplinary, and it connects broad areas of algebra and geometry. It naturally splits into three parts. The first aims to investigate one of the most fundamental properties of curves, namely contractibility, with non-commutative deformation theory. It will generalize classical results using modern language, at the same time producing many new explicit examples of rational curves in threefolds. Linking contractibility and non-commutative algebra will bring deep consequences for the birational and enumerative geometry of Calabi-Yau varieties, advancing areas of string theory. The second part studies surfaces with mild positive curvature (Fano, but with ineffective anticanonical bundle). The main objective is to prove a mirror theorem, packaging physical information with tools of homological algebra. The new heuristics, definitions, and techniques will open up an avenue to investigate higher dimensional settings. The third part involves reconstructing varieties from associated categorical data. I will tackle some hard open cases, developing new tools and combining them with classical methods.

Keywords: non commutative deformations derived categories homological mirror symmetry fano varieties birational geometry rational curves semiorthogonal decompositions categorical torelli theorems
Opto-valleytronic moiré polaritons (2DValley)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-08-01
End date: 2024-07-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: CLOSED

The emerging field of opto-valleytronics based on two-dimensional (2D) transition metal dichalcogenides (TMDs) has the potential to revolutionize quantum information processing by enabling all-optical quantum photonic circuits with nonlinear and non-reciprocal devices, such as optical switches and isolators. Such devices are inherently difficult to realize because photons generally do not interact and flow in both directions due to time-reversal symmetry. In this action, I propose to develop novel optical microcavities with embedded TMD heterostructures to achieve photon-photon interaction and directional light propagation. A small twist angle between TMD heterobilayers gives rise to hybrid moiré excitons exhibiting a permanent dipole moment in addition to increased lifetimes and oscillator strengths. Strongly coupled to a microcavity, moiré polaritons emerge with valley-contrasting dipolar optical selection rules. Moiré polaritons exhibit optical nonlinearities induced by the moiré potential. Based on all this, the overriding research objective of the project 2DValley is to develop and investigate novel opto-valleytronic devices utilizing valley-polarized moiré polaritons. To achieve this goal, I will first develop gate-tunable moiré polaritons by studying hybrid moiré excitons in cryogenic optical spectroscopy and then embedding them into optical microcavities. I propose to lift the valley degeneracy of moiré polaritons with an external magnetic field, providing control over the valley degree of freedom. Finally, I propose to replace the external magnetic field by an internal built-in magnetic field via 2D ferromagnets, which enables unprecedented intrinsic control of the valley degree of freedom by lifting valley degeneracy via magnetic proximity exchange interaction. Such nonlinear and non-reciprocal opto-valleytronic devices would have potential technological and societal impact by increasing information processing speed, volume, and security.

Keywords: opto valleytronics,moir polaritons,moir excitons,transition metal dichalcogenides,2d magnets,valley polarization
Industrial Manufacturing strategies for distributed control and resilient, rapidly responsive and reconfigurable supply chains. (MODUL4R)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Made in Europe (co-programmed)
Countries involved: Germany,Greece,Spain,Italy,Luxembourg,Portugal,Finland,Austria,Switzerland
Call: Excellence in distributed control and modular manufacturing (Made in Europe Partnership) (RIA) (HORIZON-CL4-2022-TWIN-TRANSITION-01, 2022)
Start date: 2023-01-01
End date: 2026-06-30
Duration (months): 42.0
Total project cost (EUR): 5999941.26
EU funding (EUR): 5999941.25
Participants: 21
Project status: SIGNED

EU manufacturing is constantly becoming “more productive with less”, both in terms of material usage and energy consumption. The dynamics of global markets demand shorter product lifecycles and higher product variety, impacted by an increased volatility in demand. Traditional manufacturing systems are unsuitable to meet the new “think small” paradigm. They enable flexibility but at high operational complexity and for high volume operations to get lower cost production. To realise resilient factories and supply chains, it is mandatory to reduce complexity and cost of plug & produce modular manufacturing. MODUL4R envisions reliable, maintainable, affordable, (re)usable, and changeable SME-friendly autonomous modular factories and supply chains, able to manufacture new product in low-volumes and rapidly respond to unexpected events as well as the overall supply chain. MODUL4R proposes a holistic framework applicable both to new and existing manufacturing lines to achieve flexibility, rapid responsiveness, and sustainability. MODUL4R will be demonstrated in specialized mould manufacturing for the automotive sector, CPPS for flexible & modular assembly of PCBs, and tools manufacturing for the aerospace. MODUL4R focuses on 4 pillars, offering HW and SW components: Pillar 1: Resilience against changes in customer and societal demands and disruption on the supply chain Pillar 2: Modular technologies for flexible manufacturing operations Pillar 3: Simulation and interfaces to the Industrial Metaverse Pillar 4: Human centred technologies and upskilling The impact of MODUL4R for the EU Manufacturing industry, but also the society itself, can be summarised as follows: (i) Process ramp-up time (>20%), (ii) Speed in product shifting (>29%), (iii) Yield & CpK (>12% & >21%), (iv) OEE (>21%), (v) Part cost reduction (>15%) with over 41 MEUR ROI for the consortium, (vi) 408 new jobs, and (viii) help industry to reduce Energy consumption (>30%) through Automation of processes (>25%).

Keywords: production,digital manufacturing,modularity,ai,sustainability,human in the loop,capp,open source protocols,industrial strategies
A new ERA for Environmental Risk Assessment: Chirality as a tool towards environmentally safe pharmaceuticals (ERA-ARE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Portugal,Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2023-03-01
End date: 2028-02-29
Duration (months): 60.0
Total project cost (EUR): 1499950.0
EU funding (EUR): 1499950.0
Participants: 2
Project status: SIGNED

The detrimental effects on ecosystems and human health caused by the emerging contamination of aquatic environment by pharmaceuticals urges a disruptive prevention strategy. These drugs, their metabolites and transformation products (TPs) are stable, poorly biodegraded, and recalcitrant. Though novel mitigation measures have been proposed, they are insufficient and often risky due to the possible generation of TPs. Under this increasingly deteriorating scenario for future generations, ERA|ARE aspires to build a strong ground for the realization of an internationally leading research group dedicated to promoting environmental safety. ERA|ARE approach is based on fundamental understanding of enantioselectivity of environmental processes that can impact the fate/behaviour of pharmaceutical contaminants. Fluoroquinolones (FQs), a group of chiral fluorinated antibiotics/anti-cancer agents will be explored as a proof of concept, since most small molecules approved in the last years are either fluorinated and/or chiral, presenting a stable C–F bond and a potentially enantioselective bioactivity. To attain its goals, ERA|ARE will exploit the chirality of selected FQs as a piloting tool to: 1) realize the impact of stereochemistry on antimicrobial resistance (key innovation) by testing the hypothesis that antibiotic resistance (AR) may be acquired in (and not only spread/disseminated by) wastewater treatment plants (never verified before); 2) reveal how to better select drug candidates by biodegradability; 3) pave the way for future directions of Environmental Risk Assessment (ERA); and 4) avoid ecotoxicological effects and bioaccumulation. ERA|ARE will contribute to reduce AR (expected to cause 10 million deaths/year by 2050), raising the alert level for environmental protection and sustainability. ERA|ARE will rebrand the relationship pharmaceutical industry vs environment by disrupting the ERA process and creating pioneering guidelines for the pursuit of safer drugs.

Keywords: chiral pharmaceuticals,contaminants of emerging concern,enantioselective processes,transformation products,environmental sustainability,biodegradability,antibiotic resistance,ecotoxicological effects,bioaccumulation