Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Postural networks: linking cognitive and motor control across the lifespan (POSTURENET)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 187572.48
EU funding (EUR): 187572.48
Participants: 1
Project status: CLOSED

Almost every movement we make requires the coordination of multiple muscles. How the central nervous system coordinates these patterns of muscle activity remains largely unknown. Here I propose muscle networks as an innovative and principled approach towards neural interactions underlying coordinated movements and posture to address this outstanding problem. Recent findings show robust patterns of neural coupling across multiple muscles. Application of network theory has brought about a paradigm change in brain research and has been crucial for understanding how neurons and neuronal structures connect and communicate. Here I will extend the approach used to study brain networks to the neuromuscular system and investigate the neural interactions within the brain and spinal cord involved in postural control using network analysis of brain and muscle activity (EEG & EMG). By relating network structure to postural kinematics obtained using 3D motion-capture technology, I will investigate the functional role of postural networks in healthy participants performing postural tasks and to map changes in postural control across the lifespan. Cognitive control and sensorimotor functions will be assessed using standardized test and correlated with network metrics to explain variability in postural control and disentangle their role in organizing of postural networks. By combining advanced computational analyses with state-of-the-art recording techniques, the project will enable reconstructing functional interactions in the distributed motor system from non-invasive recordings. Postural networks hence offer a promising new perspective on a long-standing open question in movement neuroscience. The expertise of my supervisors and the excellent facilities at Maastricht University provide an ideal environment in which to conduct this project and establish my own research group at a leading research institute in Europe.

Keywords: motor coordination,network physiology,brain body interactions,functional connectivity,electrophysiology
Injury profiles and brain development after mild traumatic brain injury in children: An individualised and longitudinal approach (INITIATE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-04-01
End date: 2023-03-31
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: CLOSED

Paediatric mild traumatic brain injury (pmTBI) is a very common brain disorder that affects the brain during important developmental changes. The transition between childhood and adolescence (8-16 years of age) is characterised by profound changes in the brain structure and functioning. At this age period, the injury hits the still-developing brain regions underlying emotion, cognition, behaviour, and socialisation, and can result in significant long-term impairment in these functional domains. Each pmTBI is unique based on the individuality of brain injury (i.e., location and magnitude of injury) that is superimposed on the individuality of brain development (i.e., trajectory varies between children). However, the current “one size fits all” approach that consider all children with mTBI as a homogenous group, lacks the precision needed to capture these individualities. INITIATE proposes to combine, for the first-time, advanced neuroimaging techniques with an individualised and longitudinal approach to characterise the individual profile of injury and the changes in brain development following mTBI in children. This innovative approach will allow to capture the individuality of each child with mTBI and thereby to better understand the variability and complexity of the consequences of pmTBI. INITIATE findings have the potential to open new directions in research of pmTBI, and to move the field to a more individualised approach, a first step toward personalised medicine of pmTBI in the long-term. Furthermore, this fellowship will enable me to gain extensive knowledge in paediatric medicine, advanced neuroimaging and developmental neuroscience, thereby giving me the opportunity to develop into an independent researcher in the field of TBI and brain development and to lead my own research my own research group and to conduct high quality research at a European University.

Keywords: brain disorder,traumatic brain injury,children,brain development,longitudinal cohort,individualised approach,diffusion mri,resting state functional mri
Addressing MITochondrial Import by Glioblastoma cells to rewire respiratory metabolism (MITIG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-03-01
End date: 2021-07-02
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

Glioblastoma multiforme (GBM) represents the most frequent and aggressive type of primary brain tumours in adults. Despite significant advances, current treatments involving resection and radiation/chemotherapy only partially mitigate the dire prognosis for GBM, hence avidly seeking for novel therapeutic approaches against a disease with still no virtual cure and a high socio-economic impact in the EU. A common feature in GBM, as in many other cancers, is their escape to the retrograde signalling and metabolic regulation exerted by mitochondria -the bioenergetic central of the cell. Modulation of mitochondrial function thus represents a primary target to rewire metabolism and counteract tumour progression and chemotherapy resistance. MITIG capitalizes on the recent reported ability of gliomas to import exogenous mitochondria, either isolated or transferred from surrounding neural cells in the brain, to foster tumour development and malignancy in vivo. MITIG will target both paths for mitochondrial importation to remodel organelle content and address i) how incorporation of exogenous mitochondria impacts respiratory metabolism in GBM cells and iii) the relevance of this metabolic rewiring for tumour development in vivo. Departing from mitochondrial acquisition as a novel tool to redefine respiration and metabolism in cancer, MITIG will develop a comprehensive training program fostering MSCA and EU values on research, dissemination and public engagement. An international network of experts will support the training in the intersectorial, multidisciplinary facets of MITIG. In sum, while paving the way for a promising novel biomedical field, MITIG aims at providing novel therapeutic targets and overcoming long lasting questions on respiratory metabolism in GBM and cancer as a whole.

Keywords: glioblastoma,mitochondria,respiration,metabolism,organelle dynamics,intercellular communications
Porous carbon materials for Solar photoElectrolytic Disinfection (SED)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Portugal
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 147815.04
EU funding (EUR): 147815.04
Participants: 1
Project status: CLOSED

Water is one crucial natural resource since life on our planet depends on it. The transmission of serious diseases through pathogenic microorganisms in water is extremely common in the developing world and the antimicrobial resistance has increased globally. The understanding of new processes that guarantee effectively the elimination of resistant microorganisms and access to safe drinking water, is therefore of utmost importance, thus a priority in H2020 programme. The scientific aim of Porous carbon materials for Solar photoElectrolytic Disinfection (SED) project is the development of a new sustainable methodology for water treatment. It will be the first time that Ordered Mesoporous Carbons and graphene foam are used in a solar photoelectrolytic disinfection system. The societal aims are to contribute to the reduction of the proportion of people without sustainable access to safe drinking water and basic sanitation. SED project proposes an advanced oxidation process combined with specific carbon materials, which can operate under ambient temperature and pressure, developing a new low-cost technology to water treatment. Oxygen and water will be used as oxidant without the addition of consumable chemicals and without generation of potential mutagenic disinfection byproducts. If one uses solar energy to drive the photoelectrolytic process, then it becomes a truly clean technology. The Associate Laboratory LSRE-LCM (Faculty of Engineering, University of Porto, FEUP) has excellent resources and facilities to carry on this research, because it is one of the most advanced academic laboratories for carbon materials production and characterisation in the EU. The participation of the Adventech company as the partner organisation for the secondment is an excellent opportunity to develop a new research method in which the transference of knowledge is one of the principal aims. These are excellent conditions for the development of SED project by Dr Velo.
Textile-based Wearable Mechanotheraphy Device with Liquid/Vapor Phase Change Actuation (RoboTexTherapy)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Türkiye
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 157355.52
EU funding (EUR): 157355.52
Participants: 1
Project status: CLOSED

Soft Tissue Manipulation (STM) is a powerful and direct form of mechanotherapy, which has significant implications in physical rehabilitation, disease prevention and health promotions. Different types of devices for manipulating muscle tissue have been developed for clinical applications and pneumatic compression devices are already in the market and widely used. However, these systems have limited control modalities and lack of monitoring the forces being exerted to the body during the application and previous studies have shown that the loading conditions of soft tissue have a crucial effect on the mechano-therapeutic treatment. One of the main drawback of the pneumatic compression systems is they do need rigid and bulky pumping systems for the implementation of mechanotherapy and this requirement greatly reduces the mobility of the device. Furthermore, rigid-body industrial robotic manipulators have also been used for mechano-therapeutic applications. Although these systems have the ability to perfectly manipulate soft tissue and apply controlled forces, they are expensive and do not enable safe human-device interaction due to their rigid nature. Overall, to address the challenges above I will employ textile materials to achieve both sensing and actuation with the help of phase change property of low boiling point liquids. The textile-based approach will lead to system that are lighter and mobile and safe for human-device interaction. Its successful completion will contribute to the acceleration of the soft tissue providing better and more effective therapies in terms of wearability comfort, mobility and power consumption. By combining my existing skills with newly acquired skillset that will be gained during the fellowship I will have an opportunity for securing a permanent academic position within Marmara University or a top-tier European university and starting my own research group.

Keywords: textile actuators,mechanotherapy,soft sensors,heating textiles,conductive fabrics
Precise subarea specific irrigation and fertilization system (Green-DROP)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: SME instrument
Countries involved: Germany
Call: Stimulating the innovation potential of SMEs for sustainable and competitive agriculture, forestry, agri-food and bio-based sectors (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2018-04-01
End date: 2020-12-31
Duration (months): 33.0
Total project cost (EUR): 1384237.5
EU funding (EUR): 968966.25
Participants: 1
Project status: CLOSED

Competitive global markets, rising fertilizer and energy costs, and growing uncertainties in water availability, due to a more and more uneven rainfall distribution, impose serious challenges on the European agricultural producers. Besides, wastes from farms with high nutrient availability as manure from animals, digestate from biogas plants and sewage sludge are becoming difficult and expensive to dispose. In response to these challenges and in order to achieve an efficient application of resources more and more farmers are introducing approaches of “precision agriculture” technologies for farming practices, such as Green-DROP. Green-DROP uses a number of georeferenced layers with different information: crop type, topography, weather distribution, field capacity, soil type, etc. This information gives the precise and specific requirements of water and nutrients for each subarea of the holding to be fertigated. Green-DROP makes possible to meet the exact fertilizer and water demands for all types of soils and crops. Thus, Green-DROP enables the farmer to increase productivity, resource efficiency, compliance and competitiveness in the production of raw materials, while mitigating environmental impacts from water abstractions and fertilizer application. Additionally, Green-DROP project will recover nutrients from farming wastes, and will use them as input for the fertilization of the land to close the nutrient cycle (Nutrients in waste-Nutrients as fertilizers-Nutrients in plants). Green-DROP reduces water and fertilizers consumption by 20 % making the agricultural sector more independent and profitable. It is designed for farms of all sizes but it will focus on holdings and agricultural cooperatives with at least 50 ha of surface area.

Keywords: automatic system,fertigation,efficient use of resources,water savings,sensors,precise farming,low cost,waste reuse,increase productivity,state of the art technologies
States, firms and, sustainable economic growth: A view from the periphery (PERIGROWTH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United States,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-01-01
End date: 2020-12-31
Duration (months): 36.0
Total project cost (EUR): 269857.8
EU funding (EUR): 269857.8
Participants: 3
Project status: CLOSED

Persistent socioeconomic cleavages between world-leading and late industrialising peripheral countries threaten the post-crisis recuperation and undermine the sense of solidarity necessary to address the world’s most pressing challenges. Attenuating core-periphery asymmetries will be contingent on the ability of peripheral countries to generate sustainable economic growth, but there is no simple solution to achieve this. My project will address this challenge through a direct analysis of the productive and institutional structures of the two largest and most diversified peripheral economies, Spain and Korea, between 1985 and 2011. Using detailed case-studies of three industries based on a modified Global Value Chain methodology, the research will explore the character of state-firm interactions in these two countries and their role in shaping strategies for economic transformation as they upgraded from mid- to high-income economies. I will contend that upgrading in Spain and Korea was based on three factors: proactive states, coherent state structures, and symbiotic or co-dependent state-firm interactions. However, I will show that variations in the strategic and financial resources of state and firms, and in the influences of role-model countries, led Spain and Korea to pursue a different sectoral specialisation in complex services and manufacturing respectively. The research will be carried out at the University of California San Diego and the London School of Economics. The output will consist of a monograph and three academic papers. This project will enhance my career prospects by establishing me as an expert in economic transformation, expanding my publication record, developing my skills in international project management, and strengthening my international professional networks in the US and Asia. No less importantly, the results of the project will contribute to current European goals for smart, sustainable and inclusive growth.

Keywords: industrial transformation,sustainable economic growth,upgrading,state firm relations,state activism,competitiveness
PRecise Instrument MEtering SYSTem (PRIMESYST)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Flexbimec is a global hydraulics manufacturing company with 28 dedicated employees, 9.5M€ turnover, 2,500 strong customer base and 40 years’ experience providing Measuring Instruments (MI) for fluid metering and dispensing devices. We built a brand new line of fluids metering and dispensing equipment conforming to a mandatory MI directive aimed at the Automotive segment focusing on fluid management systems. Typical problems included increased fluid consumption and the inability to detect and trace the flow of fluid, leading to problems with fluid measurement, machine maintenance, leaking fluid and poor working environments. We increased sales by 60% and consolidated our foothold internationally. Our next product generation will boost EU sales, while appealing to a very large audience globally: PRIMESYST extends our original concept through refinement of the core components and integration of sensors and software–enabled data collection system to control and manage the flow of lubricant into any industrial activity. Data can be logged, analysed and displayed using specialised software which has been built upon an existing simulated application. New target sectors are Industrial Equipment, Mining and any other sector where fluid management systems or machines exist. End-users benefit with 50% cost savings, 75% timing reductions, access to unique data and supreme performance levels. Tidier and less polluted workplaces will result from increased visibility to maintain fluid handling machines. We foresee a 30% decrease in fraudulent activity when measuring fluids and all key directives conformed to. We will secure a 35% share of the EU Fluid Management Systems market and 70% for the Italian market by 2025, plus global sales increase by 23%. In 4 years, we expect our Return on Investment to be 1.48 per Euro invested in the Project. We expect to increase headcount by 30 and reach a €11.4 million in profit.

Keywords: measuring instruments,fluid management system,fluid metering,dispensing,fluid,liquid,2014,fraud,traceability
Supporting the decision-making in URBAN transformation with the use of dIsruptive TEchnologies (URBANITE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Innovative societies
Action type: Research and Innovation actions
Countries involved: Italy,Spain,Italy,Germany,Spain,Finland,Slovenia,Netherlands
Call: Transformative impact of disruptive technologies in public services (H2020-SC6-TRANSFORMATIONS-2019, 2019)
Start date: 2020-04-01
End date: 2023-06-30
Duration (months): 39.0
Total project cost (EUR): 3954062.5
EU funding (EUR): 3954062.5
Participants: 11
Project status: SIGNED

Cities are facing a revolution in urban mobility. Emerging start-ups are offering innovative mobility solutions to satisfy the demand of the growing population, both living or moving into the cities every day. We are moving from the concept of owning to sharing a vehicle; from using public transport services to moving around with a hop on/off bike or electric scooter; disruptive start-ups (Uber, Cabify) are shaking up traditionally established business models... But this innovation is also bringing up unforeseen consequences that public administrations need to manage. Electric scooters driven in pedestrian areas are posing safety risks and even pedestrian kills; piles of broken bikes are laying around in streets; protests and strikes by taxi drivers; electric charge points need to coexist with the growing demand for public parking spaces. It is in this new context that public administrations need means to help them understand this new scenario, supporting them in making policy–related decisions and predicting eventualities. There is a need of a platform that can harvest, fuse and curate data from heterogeneous sources, that can extract knowledge to help in the decision-making processes and simulation of solutions to anticipate behaviours and delimit unforeseen consequences. Besides, such intelligent platform can foster cross-departmental collaboration by eradicating internal silos. URBANITE will analyse the impact, trust and attitudes of civil servants, citizens and other stakeholders with respect to the integration of disruptive technologies such as AI, DSS, big data analytics and predictive algorithms in a data–driven decision-making process. To this end, URBANITE will provide recommendations, pathways and toolkits (both ICT-based such as data management platform and DSS, and non-ICT such as co-creation activities and a repository of social-related assets) for city managers. Results will be validated in 4 real use cases: Amsterdam, Bilbao, Helsinki and Messina.

Keywords: artificial intelligence,big data analytics,co creation,economy sharing,mobility,urban transformation