Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Vascular Endothelial interactionS and SpEciaLization (VESSEL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany,Italy,Finland,Spain,Germany,Sweden,Switzerland
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 4086572.39
EU funding (EUR): 4086572.39
Participants: 9
Project status: CLOSED

The vascular network plays essential roles in animal biology. Local disruption or impaired function of the vascular network is known to cause various pathological conditions, such as ischemic heart disease and stroke. The angiogenic growth of blood vessels is critically required during development, growth and regeneration, but it can also promote the growth of cancer cells and contribute to diabetic retinopathy and other diseases. Various blood vessels possess different biological characteristics in order to fulfil their tissue- and organ-specific roles. The VESSEL network brings together 12 academic and industrial partners with a common interest in morphogenesis of blood and lymphatic vessels and their role in tissue homeostasis. This training program covers major research areas from embryonic development of blood and lymphatic vessels, to the analysis of their structural integrity and function in various adult tissues in normal and pathological conditions, and aims to address critical demand to provide state-of the-art training for future specialists in vascular biology working in academia, industry and health care systems. By employing cutting edge innovative technologies, this project establishes strong bonds between academic and industrial partners and has a strong potential to generate new IP in this area. This project has a strong clinical relevance based on gaining insight into critical vascular biology processes and on developing novel cutting edge imaging and drug delivery technologies. Through cooperation of the different Centres, the VESSEL consortium will develop integrated, highly specialized, curricula for young scientists, which will open new career perspectives in academia and industry.

Keywords: vessel,endothelial cell,bbb,lymphatics,vascular growth,vasculogenesis,angiogenesis,vascular specification,cell signaling
Architecture, Design and Art Practice Training ‐ research (ADAPT-R)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium,Slovenia,United Kingdom,United Kingdom,Spain,Estonia,Denmark
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 4009494.71
EU funding (EUR): 4009494.71
Participants: 7
Project status: CLOSED

The ADAPT-r ITN aims to significantly increase European research capacity through a unique and ground-breaking research model: at its core is the development of a robust and sustainable ITN in an emergent Supra-Disciplinary field of research across a range of design and arts disciplines – creative practice research. ADAPT-r will train new researchers, increase supervisory capacity, partner with private sector SMEs in research projects providing substantial opportunity for real world testing of the research and real world training, and introduce creative practice research methodologies to a new generation. The unique model proposed will enable ADAPT-r to substantially leverage the number of doctoral candidates within the ITN budget model maximising higher degree training opportunities. The research that is produced through the ADAPT-r ITN will contribute to a wider research effort to increase knowledge, understanding and quality of research in creative disciplines and its methods. The Marie Curie ITN funding will enable an existing bi-lateral research training relationship to be expanded to include multiple partners from across Europe to create a greatly enhanced international research training network with a long-term future. The ADAPT-r ITN will address identified deficits in EU research training for creative disciplines. Through training creative practice researchers in the explication and dissemination of tacit knowledges and latent cognitive resources the ADAPT-r ITN will make a substantive contribution to meeting EU 2020 priorities by building a new generation of creative practice researchers and research lead practitioners able to meet the complex and often competing demands of contemporary Europe. Implementation of the ADAPT-r ITN will result in 32 Fellowships, 8 training conferences, a major research conference, a major exhibition, three key books, and a web site providing public access to research and events.

Keywords: design practice research,artistic research,research by design,creative practice research,practice based research,embedded practice research,architecture,design,arts
Next-generation integrated MNBS-platform for instant diagnostics with single-molecule resolution (NEXTDX)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Alternative Paths to Components and Systems
Action type: Collaborative project
Countries involved: Netherlands,Belgium,Germany,Finland,Norway,Germany
Call:  (FP7-ICT-2011-8, 2011)
Start date: 2012-12-01
End date: 2015-11-30
Duration (months): 36.0
Total project cost (EUR): 5375040.0
EU funding (EUR): 3608000.0
Participants: 7
Project status: CLOSED

A spearhead function that lies within the promise of MNBS technologies is the rapid and sensitive detection of biomarker molecules in raw biological samples. However, it has been very difficult to realize the promise due to two key challenges: the signal-over-background challenge, i.e. many biomarkers have very low concentrations and real-life biological samples generate very high background signals, and the integration challenge, i.e. it is very difficult to conceive a system that has a very high performance and is still fully integrated, miniaturized, and cost-effective. NextDx will address these challenges by investigating an integrated system for protein biomarker detection with single molecule resolution. The system is based on magnetic nanoparticles that are controlled by electromagnetic fields and detected with nanometer precision in an integrated optical chip with bio-engineered surface. The system will allow a sharp biophysical discrimination between biomarker-induced and non-biomarker-induced nanoparticle binding signals, so as to approach the fundamental limit of counting statistics in real biological samples. This is a unique, novel, and timely approach. At the end of NextDx, we will demonstrate an integrated MNBS platform technology for extremely sensitive protein detection, within a few minutes, directly in blood plasma. The technology will be suitable for multiple biomarker testing outside the hospital, to improve for example the lives of chronically ill patients. NextDx is a unique international consortium with best-in-class partners contributing complementary physical and biomolecular engineering expertise, supported by an advisory board with all relevant stakeholders (clinicians, patient organisation, insurance company, regulatory agency). Together, all are focused on generating new insights in MNBS integration and on effective industrial-academic collaboration on the European scale towards next-generation integrated diagnostics.

Keywords: mnbs,platform,biomarker,single molecule resolution,diagnostics
Quantum sensor technologies and applications (QTEA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,United Kingdom,France,Germany,Greece,Switzerland,Denmark,Germany,Germany,United Kingdom,Denmark
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2016-09-30
Duration (months): 48.0
Total project cost (EUR): 4179498.4
EU funding (EUR): 4179498.4
Participants: 11
Project status: CLOSED

This training network focuses on the development of modern quantum sensors based on precision measurements of inertial forces, electro-magnetic fields, and time. Important ideas and major contributions to current research in this field have originated from atomic physics and quantum optics. The topics covered are gravitational probing, rotational sensing, field probes, and atomic clocks, with potential future applications ranging from fundamental science to geological exploration, navigation and medical diagnostics. The consortium will train a cohort of young researchers on the physics of atomic clocks and interferometers, which form the basis of quantum sensors, and several techniques to realise technologically relevant devices. The envisioned designs incorporate micro-structured components for trapping and guiding of atoms and photons. With this approach we aim for a high level of integration and advantageous parameter regimes, which will widen the range of possible applications by addressing aspects of sensitivity and bandwidth of measurements, alleviating access restrictions to points of interest, and improving mobility for field applications. We complement the range of topics by including surface probes, field sensitive microscopes, and molecular spectroscopy, deepening the connections to other scientific disciplines. The partner consortium is an exceptional combination of industrial and academic stakeholders, ranging from technology suppliers to users, supported by, e.g., the European Patent Office and the Research Policy Institute to assist the innovation process. The research training covers physical principles and technological aspects from development to implementation, with input from industrial partners on truly relevant needs. It is complemented by training on societal aspects, intellectual property rights, and transferable skills training, thus addressing a wide skill set that unites technical expertise with an innovative mindset.

Keywords: p107 atomic - molecular physics,p108 optics and quantum optics,p116 metrology and measurement,atomic magnetometers and surface probes,atomic clocks
European Doctorate in Image Sensors with Optical Nanotechnology at Glasgow and Awaiba (EDISON-GA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Portugal,United Kingdom
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-11-01
End date: 2017-10-31
Duration (months): 60.0
Total project cost (EUR): 1467957.0
EU funding (EUR): 1467957.0
Participants: 3
Project status: CLOSED

Digital cameras designed with CMOS image sensors are one of the fastest growing sectors of the consumer electronics market. With increasing number of pixels and improving image quality, they have found applications in a range of systems from mobile handsets to space observatories. Despite this growth, they still suffer from limited dynamic range and poor colour discrimination abilities. Furthermore, increasing number of pixels have led to increasing power dissipation in these sensors. This project would train early stage researchers in the design of image sensors utilising optical nanotechnology, in particular plasmonic filters. These filters would help improve the colour response of the next generation of sensors. More importantly, the project would also develop a large format high intensity imager, which would be useful for improved radiotherapy in the treatment of cancer. The network would provide training and research opportunity to ESRs in an academic, industrial as well as clinical environment.
Microscopic investigations of CO2 capture and scattering on liquid gas interface (CAPZEO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,Spain,United Kingdom
Call:  (FP7-PEOPLE-2012-IRSES, 2012)
Start date: 2012-10-01
End date: 2016-09-30
Duration (months): 48.0
Total project cost (EUR): 220400.0
EU funding (EUR): 220400.0
Participants: 3
Project status: CLOSED

The ‘CapZeo’ IRSES exchange programme gathers four partners, three from Europe (Université Paris-Est Marne-la-Vallée, France – UPEMLV, Instituto de Estructura de la Materia, Spain – CSIC, and University of Hull, United Kingdom) and one partner from Morocco (Université Mohamed V-Agdal Rabat, Morocco – UM5A).Three from Europe (UPEMLV, CSIC and UULM) and one from Morocco (UM5A). This project includes an international symposium, a summer school and two scientific work packages. The first scientific work package focuses on the electronic structure calculations necessary to model the adsorption of CO2 on the Zeolitic Imidazolate Frameworks (ZIFs) at the atomic level. The parameters for the interaction between ZIFs-CO2 and CO2-CO2 pairs will be deduced and optimised, in order to maximise the capture of CO2. These microscopic parameters will be incorporated later into the macroscopic description to investigate the dependence on pressure and temperature of the adsorption process. The second scientific work package deals with the theoretical study of CO2 scattering on a liquid-gas interface at the microscopic level. The liquid side of the interface is modelled by a monolayer of ZIFs subunits adsorbed on a gold surface. The stereodynamics of CO2 scattering on these model surfaces will be treated.

Keywords: c101 physical chemistry,c104 molecular architecture and structure,c115 theoretical and computational chemistry,c131 environment chemistry,c142 molecular chemistry
Accountability For Cloud and Other Future Internet Services (A4CLOUD)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Pervasive and Trusted Network and Service Infrastructures
Action type: Collaborative project
Countries involved: United Kingdom,Greece,United Kingdom,France,France,Germany,Sweden,United Kingdom,Germany,Norway,Netherlands,Spain
Call:  (FP7-ICT-2011-8, 2011)
Start date: 2012-10-01
End date: 2016-03-31
Duration (months): 42.0
Total project cost (EUR): 14006686.0
EU funding (EUR): 9958888.0
Participants: 13
Project status: CLOSED

Cloud and IT service providers should act as responsible stewards for the data of their customers and users. However the current absence of accountability frameworks for distributed IT services makes it difficult for users to understand, influence and determine how their service providers honour their obligations. A4Cloud will create solutions to support users in deciding and tracking how their data is used by cloud service providers. By combining methods of risk analysis, policy enforcement, monitoring and compliance auditing with tailored IT mechanisms for security, assurance and redress, A4Cloud aims to extend accountability across entire cloud service value chains, covering personal and business sensitive information in the cloud. A4Cloud solutions will support service providers in preventing breaches of trust by using audited policy enforcement techniques, assessing the potential impact of policy violations, detecting violations, managing incidents and obtaining redress. A4Cloud aims to improve the acceptability of cloud-based infrastructures where critical data is perceived to be at risk. It will develop techniques for improved trustworthiness of cloud ecosystems as prerequisite for accountability. Therefore it will create policies and tools that enforce responsibilities while striking a balance between transparency and privacy, and determine issues and constraints for regulators, corporate and institutional service providers, users, and their end-users. A4Cloud will have a lasting impact on the competitiveness of the European ICT sector by addressing major perceived barriers to trustworthy cloud-based services. These include concerns about complexity and enforceability of legal, regulatory and contractual provisions, socio-economic and corporate constraints, issues of trust for service-users such as risk-mitigation, privacy, confidentiality and transparency, and operational challenges such as interoperability and enforcing and monitoring compliance.

Keywords: accountability,assurance,cloud,future internet,governance,interoperable policies,liability,metric,privacy,risk,security,socio-economic models,supply chain,transparency,trust,verification
OPerational Trustworthiness Enabling Technologies (OPTET)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Pervasive and Trusted Network and Service Infrastructures
Action type: Collaborative project
Countries involved: France,Germany,Germany,Greece,United Kingdom,Greece,Norway,Israel,France,France,Netherlands,Germany,France,Belgium
Call:  (FP7-ICT-2011-8, 2011)
Start date: 2012-11-01
End date: 2015-10-31
Duration (months): 36.0
Total project cost (EUR): 10707039.0
EU funding (EUR): 7094162.0
Participants: 15
Project status: CLOSED

The OPTET project plans through a multi-disciplinary and integrated approach to identify and address the drivers of trust and confidence also fight against its erosion (especially true on the Internet or Cloud). Focus of this project is on socio-technical systems connected to the Internet. The resulting technologies enabling trustworthiness would be verified on two distinct existing execution platforms to demonstrate genericity of OPTET outcomes. Potential of OPTET results will be demonstrated and evaluated in the context of two operational use cases one in the domain of Ambient Assisted Living (AAL) and second Cyber Crisis Management. Overall, the OPTET project will significantly increase the trustworthiness of IT and Services and thus strengthen the competitiveness of the European software and service industry. In doing so OPTET will provide a powerful foundation for designing and developing trustworthy system/services/apps stakeholders can trust (since provable also guaranteed) for the future internet realizing its promises.

Keywords: future internet,trustworthy design and execution platform,trustworthy app factory,secure service market place,socio-technical systems,service delivery,internet of services,open apis
A New GEnetic LABoratory for non-invasive prenatal diagnosis (ANGELAB)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Alternative Paths to Components and Systems
Action type: Collaborative project
Countries involved: Spain,Germany,France,Spain,Poland,Cyprus,United Kingdom,Austria,Spain,Spain,Germany
Call:  (FP7-ICT-2011-8, 2011)
Start date: 2012-10-01
End date: 2017-06-30
Duration (months): 57.0
Total project cost (EUR): 11429587.0
EU funding (EUR): 8265938.0
Participants: 15
Project status: CLOSED

This project will develop a family of In-Vitro Diagnostic Systems that will transfer for the first time novel Non Invasive Prenatal Diagnostic (NIPD) methods in tube to a LabonaChip format. This family will consist of three research systems chosen to cover all prenatal diagnosis models: - ANGELAB1. This system will use a LabonaChip to extract fetal DNA from the mother´s plasma based on differences in methylated pattern between fetus and mother and captured by specific magnetophoresis, plus qPCR for monogenic diseases with a known mutation for: Spinal Muscular Atrophy, Cystic Fibrosis (CF), and X-linked disorders. It will be used only for high risk population. - ANGELAB2. It will use a LabonaChip to carry out immunoprecipitation (MeDIP) for fetal DNA extraction from mother´s blood and real time quantitative Polymerase Chain Reaction (real time qPCR) for Aneuploidies of chromosomes 13, 18, 21, X and Y. It will be used for population screening purposes. - ANGELAB3. This system will use the DNA sample provided from ANGELAB1 or ANGELAB2 and it will carry out Digital PCR on a LabonaChip to detect: CF (unknown multiple mutations), b-thalassemia and achondroplasia. I will be used for population screening purposes. All systems can manage 8 samples at a time. They can be modularly assembled to themselves, offering a system adaptable to different throughput needs. The consortium will also develop and integrate a LabonaChip Pilot Production Line (LPPL): - LPPL: This pilot line setup will provide a sustainable and economic LabonChip manufacturing. Materials, processes, and their life cycle will be considered. The environmental assessment will be carried out following ISO 14044. Quality control tools will be integrated along the entire production chain of LabonaChips. This project will end with the implementation of these three diagnostic systems as pilot routines in two Hospitals through a technical validation of 700 pregnancies.

Keywords: nipd,non-invasive,prenatal diagnosis,labonachip,fetal dna,extraction,quantum dots,digital pcr,dpcr,qpcr,medip,aneuploidies,cystic fibrosis,mutation
NAnoSCale Engineering for Novel Computation using Evolution (NASCENCE) (NASCENCE)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Future and Emerging Technologies
Action type: Collaborative project
Countries involved: Netherlands,United Kingdom,United Kingdom,Norway,Switzerland
Call:  (FP7-ICT-2011-8, 2011)
Start date: 2012-11-01
End date: 2015-10-31
Duration (months): 36.0
Total project cost (EUR): 3690146.0
EU funding (EUR): 2900000.0
Participants: 5
Project status: CLOSED

The aim of this project is to model, understand and exploit the behaviour of evolving nanosystems (e.g. networks of nanoparticles, carbon nanotubes or films of graphene) with the long term goal to build information processing devices exploiting these architectures without reproducing individual components. With an interface to a conventional digital computer we will use computer controlled manipulation of physical systems to evolve them towards doing useful computation. During the project our target is to lay the technological and theoretical foundations for this new kind of information processing technology, inspired by the success of natural evolution and the advancement of nanotechnology, and the expectation that we soon reach the limits of miniaturisation in digital circuitry (Moore's Law). The mathematical modelling of the configuration of networks of nanoscale particles combined with the embodied realisation of such systems through computer controlled stochastic search can strengthen the theoretical foundations of the field while keeping a strong focus on their potential application in future devices. Members of the consortium have already demonstrated proof of principle by the evolution of liquid crystal computational processors for simple tasks, but these earlier studies have only scraped the surface of what such systems may be capable of achieving. With this project we want to develop alternative approaches for situations or problems that are challenging or impossible to solve with conventional methods and models of computation. Achieving our objectives fully would provide not only a major disruptive technology for the electronics industry but probably the foundations of the next industrial revolution. Overall, we consider that this is to be a highly adventurous, high risk project with an enormous potential impact on society and the quality of life in general, including medicine, everyday household items, energy-saving policies, security, and communication.

Keywords: unconventional computation,evolutionary computing,genetic algorithms,evolving nanosystems,evolvable hardware,nanoparticles,carbon nanotubes,evolution-in-materio,programmable nanosystems