Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Development of an organic photovoltaic module that generates energy from ambient light (LAYER®)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator Challenge: Technologies for ‘Fit for 55’ (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 2567282.5
EU funding (EUR): 1622881.0
Participants: 1
Project status: CLOSED

Lithium-ion batteries (LIBs) are one of the most important electrochemical energy storage system for IoT devices (in 2015, 5.6B LIBs were sold worldwide). However, lithium mining is extremely damaging to the environment and it harms the soil and causes air contamination. Furthermore, the typical estimated life of a LIB is about very short, 2/3 years or 300 to 500 charge cycles, whichever occurs first. Dracula Technologies has developed the LAYER, the green alternative to LIBs. The LAYER® is an OPV module produced through inkjet printing that generates energy from ambient light and that is specifically designed for IoT devices, such as smart home tools. It consists of 2 electrodes,2 interfacial layers and the active LAYER®, made of organic raw materials (semiconducting organic molecules or polymers, fullerene derivatives, non-fullerene derivatives). It is less than 5mm thick and its power conversion efficiency (PCE) under outdoor and indoor illumination is respectively 12% and 25%.
COmpton Scatter based Imaging for Nuclear Emissions (COSINE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-04-01
End date: 2028-03-31
Duration (months): 24.0
Total project cost (EUR): 202125.12
EU funding (EUR): 202125.12
Participants: 1
Project status: SIGNED

The main goal of my proposal is to exploit Compton scattering in PET imaging, a nuclear imaging technique well-established in clinical routine, mainly in oncology as a tool for tumor diagnosis and monitoring, but also through preclinical PET as an essential tool for pharmacology and drug development. By considering signal events undergoing Compton scattering, I expect to increase the sensitivity of PET systems, and so improve the attainable image quality. Sensitivity in PET systems is a key parameter to be optimized, as it could allow for dose exposure and/or scan time reduction, in addition to being critical in low-count regime scenarios, for pediatric patients, and in research applications involving small-animal imaging. Aside from increasing the sensitivity, the purposeful detection of Compton scattering in PET imaging opens the door for the use of this modality for new applications (e.g. immunoPET, theranostics...). However, incorrect/simplified modeling of these events can degrade PET image quality. My proposal relies on developing algorithms and models based on solid mathematical and physical foundations, able to include events involving Compton scattering into dedicated reconstruction frameworks. To this end, I intend to use the knowledge I have acquired during my PhD developing similar models and algorithms for imaging with Compton cameras. Specifically, I intend to address three questions: first, the inclusion of inter-crystal scatter events with particular focus on small-animal PET imaging; second, the modeling of object scattered events and their use in low-count regime scenarios; and third, the treatment of coincidence events that involve an additional emission of photons, either correlated or uncorrelated to the positron emission. The evaluation of the proposed methods will be carried out using both Monte-Carlo simulations and experimental PET data, for which the facilities and technologies developed by the host team in Lübeck will be employed.

Keywords: positron emission tomography pet,inter crystal scatter ics,object scatter correction,compton camera,low count regime,theranostics,image reconstruction,monte carlo simulations
Microbial performance impacted by surfactants from glyphosate application (MICROSURF)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1499375.0
EU funding (EUR): 1499375.0
Participants: 1
Project status: SIGNED

Glyphosate is the most widely applied herbicide on Earth, exhibits potential toxicity, and persists in the environment, although microbial glyphosate degradation exists. Glyphosate is not used as single compound but as mixture, a formulation, consisting of surfactants as the second most abundant ingredient. These surfactants are considered inert and a critical knowledge gap exists regarding their impacts on microorganisms in the environment. In my seminal postdoctoral studies, we showed that surfactants can inhibit microbial activities and induce a shift in microbial communities and functions in marine settings. I hypothesize that similar effects occur in terrestrial and freshwater environments in response to surfactant-glyphosate application. In particular, I.) glyphosate-degrading microorganisms might be severely affected, probably contributing to glyphosate’s persistence in nature and II.) microbial key players that drive biogeochemical cycles might be impacted, and, thus, surfactant-glyphosate application might influence greenhouse gas formation and contribute to climate change. To systematically study the effects of surfactants and surfactant-glyphosate mixtures in light of these novel aspects, an innovative multiscale and interdisciplinary frontier research effort is required: starting with pure isolate and enrichment culture studies, followed by microcosm experiments, and advancing to field experiments, in the presence and absence of surfactants respectively, we will identify microbial key players and functions, quantify microbial activities related to glyphosate degradation as well as to biogeochemical cycles and greenhouse gas formation, and, furthermore, reveal common principles of surfactant effects. This pioneering research will holistically unravel the impacts of surfactants on microorganisms in the environment and has the potential to influence politics, society, technology, and science (microbial ecology, biogeochemistry, and Earth sciences).

Keywords: surfactants,glyphosate,omics,metagenomics,metatranscriptomics,nanosims,cryo fib sem,cultivation,microcosms,field study,greenhouse gases,n cycle,c cycle
Unlocking the Potential for Agricultural research on an EU Outmost region: boosting ISOPlexis centre (isUP-AgrO)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Panel: Environment and Geosciences
Countries involved: Portugal,Italy,Spain
Call: Twinning Bottom-Up (HORIZON-WIDERA-2023-ACCESS-02, 2023)
Start date: 2024-07-01
End date: 2027-06-30
Duration (months): 36.0
Total project cost (EUR): 1464399.35
EU funding (EUR): 1431827.92
Participants: 4
Project status: SIGNED

Agricultural RTD is important for global food security and environmental sustainability. The isUP-AgrO proposal aims to enhance the capability of the Research Centre ISOPlexis, located in Madeira, an outermost region of Portugal, to be a leading research center at the EU level in Sustainable Agriculture and Food Technology. ISOPlexis participates with high success in national research projects and programs participates in the Network of Genetic Banks FAO, AEGIS, and ECPGR programs, and plays a leading role in the implementation of the Regional Smart Specialization strategy priority domain for Agriculture, Food, and Bioeconomy, and its goals. However, it has not been able to reach a visible position at the European level. It is now the right moment to increase the centre´s internationalization, allowing it to participate in joint international consortiums and research projects. The isUP-AgrO proposal joins two research centres from Spain (INRA - CSIC), Italy (UNIPR), and a Portuguese innovation company (Saturntech) with the common goal of improving the research and coordination activities of the ISOPlexis - Centre of Sustainable Agriculture and Food Technology. The isUP-AgrO will offer training for young/senior scientists, develop administrative/research management skills, and foster networking through joint research, expert visits, training schools, staff exchanges, workshops, and conference attendance. The isUP-AgrO overall methodology is based on new approaches and strategies to study and improve the sustainability of the Food Production System, in this case, in the traditional vineyards of Madeira. The isUP-AgrO strives for research excellence and extensive networking to elevate the ISOPlexis Centre (University of Madeira) to be an EU reference in this field. Success will be measured by local and international network strength, training outcomes, staff exchanges, higher participation in ERA, and more coordination roles in EU projects.

Keywords: agriculture,agrodiversity,agrosystem services,precision agriculture,sustainability
Quantum Sensing with Metal-Organic Frameworks: DFT, Molecular Dynamics and Machine Learning Exploration (SEQUOIA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Ireland
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-10-01
End date: 2026-09-30
Duration (months): 24.0
Total project cost (EUR): 215534.4
EU funding (EUR): 215534.4
Participants: 1
Project status: SIGNED

Metal-organic frameworks (MOFs) are composed of metal ions coordinated with organic ligands to form porous structures with high surface areas, making them suitable for a wide range of industrial applications. For instance, MOFs exhibit sensitivity to various molecules and gases due to their high surface area and tailored pores. As such, they can be employed in gas sensors for detecting volatile organic compounds, environmental pollutants, and toxic gases, enabling important applications in environmental monitoring and industrial safety. Despite the incredible success of MOFs as a sensing strategy and sequestration agent, only macroscopic quantities of segregated compounds can be effectively sensed. My project SEnsing with QUantum OrganometallIc frAmeworks (SEQUOIA) will pave the way to the exploitation of quantum sensing for the detection of traces of gases/pollutants in air and water by exploring the potential of MOFs decorated with molecular quantum sensors. Quantum sensing is an emerging area of quantum information science that enables the measurement of physical properties using quantum objects (qubits). Quantum sensors are far more precise than their classical counterpart, potentially allowing them to probe a vast range of physical properties, from magnetic fields to gravity, with unprecedented sensitivity. In particular, molecular qubits represent one of the latest frontiers of spin-based quantum sensors, where long spin coherence times are combined with chemical versatility and the possibility to tailor molecular structures in order to tune the sensor’s properties and tailor sensor-target interactions. SEQUOIA will bring together a diverse set of advanced simulation techniques such as quantum chemistry, machine learning and ab initio spin relaxation theory to deliver an unprecedented computational characterization of the properties of MOFs in realistic environments and thus provide a blueprint for the realization of this cutting-edge technology.

Keywords: quantum chemistry,quantum sensing,spin phonon coupling
Coastal Landscapes and Roman Maritime Villas: A Comparative Regional Study of Architectural Models and Environmental Settings (CLaRMaV)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-11-01
End date: 2026-10-31
Duration (months): 36.0
Total project cost (EUR): 265099.2
EU funding (EUR): 265099.2
Participants: 2
Project status: SIGNED

Coastal heritage is increasingly at risk from both natural and man-made factors, and is therefore crucial to document it before it disappears. Maritime villas, a common feature of the Roman Mediterranean, are very important for understanding the development of ancient urbanisation and architectural forms, the interaction between humans and the environment, and the use of natural resources. Yet, an overall study looking at the architecture of Roman maritime villas in the Mediterranean regions and how they impacted on, and were shaped by, their local environments is lacking. CLaRMaV will investigate the typology of Roman maritime villas across the Mediterranean Basin (2nd century BC-6th century AD). It will do so by studying the architectural models adopted and developed in the various regions; the prevailing trends over time; the use of individual architectural spaces; and the role of these villas in the local economy. The project will focus on the dialogue between domestic architecture and the environment and look at the use of available natural resources. Special attention will be given to water usage and to whether any water-saving measures were put in place to address its scarcity in some regions. This project, with its multidisciplinary nature, will contribute to the knowledge of the architectural, environmental, and socio-economic histories of the Roman Empire. By incorporating in its methodology the use of GIS and 3-D reconstructions, the resulting outputs will be of use to archaeological sites and museums, both in managing the sites and in offering educational resources to visitors. The coastal environments occupied by ancient maritime villas are seriously impacted by coastal erosion, rising sea levels due to climate change, and anthropic actions. Therefore, it is vital to systematically record and study these structures. The data generated by the project will be useful to local authorities in charge of preservation of coastal heritage and urban planning.

Keywords: coastal heritage,preservation and promotion,architecture,roman maritime villas,mediterranean landscape,ancient urbanism,natural resources,water usage and recycling,socio economic histories
Non-Corrosive Polymer Electrolyte with Preferential Al3+ Transport for Rechargeable Aluminum Batteries (NC-PEPA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-12-01
End date: 2026-11-30
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: CLOSED

Rechargeable aluminum batteries (RABs) are extremely promising due to inherent safety, high theoretical volumetric energy density (4X of Li), and low cost of Al metal (10X cheaper than Li). RABs can play a crucial role in ensuring and securing an affordable and safer EU energy supply in line with the EU Green Deal. However, the development of RABs is hindered by a lack of practical electrolytes. The current state-of-the-art (SoA) ionic-liquid electrolytes are extremely corrosive, moisture sensitive, expensive, and do not offer Al3+- cationic species. Relying on the synergy between the researcher’s background and the host's expertise, the NC-PEPA project introduces an innovative and beyond the SoA concept to develop a non-corrosive polymer electrolyte with preferential Al3+ cationic transport with high ionic conductivity. Objectives of the project address overall issues of the SoA electrolytes. This project will have a significant scientific and societal impact as NC-PEPA electrolyte promises the development of safer, affordable, and high-energy density RABs that will be pivotal to clean and green energy transition. Additionally, it contributes to the enhancement of the EU’s scientific excellence. Being the leader of the energy storage materials subgroup within the Multifunctional Nanocomposite Group at IMDEA and with a proven track of contribution in the field, Dr. Pendashteh A. is the most appropriate supervisor. The host institute (IMDEA) is also acknowledged as one of the best research institutes in Spain, with proven experience in developing materials and systems for batteries and immense experience in Marie Curie fellows hosting and project management. The project will advance the researcher’s professional development and career growth by providing multidisciplinary skills along with access to management and related training that will equip the researcher to achieve his long-term goal of establishing a research group focused on developing sustainable batteries.

Keywords: aluminum batteries post li batteries electrolytes polymer electrolytes rechargeable batteries
Cracking the code on tumor targeting with nanostructures: competitive kinetics and extracellular vesicles (ROMEO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Spain
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 3121375.0
EU funding (EUR): 3121375.0
Participants: 1
Project status: SIGNED

Today cancer remains a huge health concern, with around 20 million new cases and 10 million deaths per year worldwide. However, according to expectations, Nanomedicine should have ended cancer long time ago. The first nanomedicine (DoxilTM) a liposomal formulation based on the Enhanced Permeation and Retention (EPR) effect, dates from 1995. In the ensuing three decades, hundreds of anticancer nanoparticles with exciting properties were developed, but only a handful have reached the clinic, with rather limited effectiveness. Recent research has identified the root causes of the failure of Nanomedicine in cancer, which can be narrowed down to two problems: first, most nanoparticles (NPs) end up in the liver, trapped by Kupffer cells (KCs) in the slow-flow sinusoids; second, of the small fraction of NPs that escape KCs most fail at delivering therapy to tumor cells, ending up in off-target cells. ROMEO has been specifically conceived to address these problems and produce a therapeutic vector able to escape KCs, while guaranteeing a high tumor cell targeting capability. To achieve this, we will combine i) extracellular vesicles (EVs) as delivery vectors of high selectivity and ii) optimized NPs, as decoys able to saturate KCs uptake capacity. A novel approach, importing chemical engineering concepts (microfluidics, competitive adsorption/reaction kinetics) will provide actionable information to improve successive generations of EVs, NPs and feeding schemes in order to keep KCs saturated and maximize delivery to tumor cells. The solutions will be validated in a ground-breaking experimental design that circumvents previous problems of in vivo experiments. The final deliverable of ROMEO will be optimized EVs containing a therapeutic load, able to survive repeated sinusoid passes thanks to the optimal feeding of decoy NPs, and with a proven ability to target tumor cells. If successful, the main problem preventing the success of cancer nanomedicine will have been solved.

Keywords: adsorption reaction kinetics,microfluidic contactors,nanomedicine
WET HORIZONS - upgrading knowledge and solutions to fast-track wetland restoration across Europe (WET HORIZONS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Climate
Destination: Climate sciences and responses for the transformation towards climate neutrality
Action type: Research and Innovation actions
Countries involved: Denmark,Netherlands,Germany,France,United Kingdom,Poland,Finland
Call: Restoration of natural wetlands, peatlands and floodplains as a strategy for fast mitigation benefits; pathways, trade-offs and co-benefits (HORIZON-CL5-2021-D1-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 5561610.75
EU funding (EUR): 5561610.75
Participants: 15
Project status: SIGNED

Wetlands are key biodiversity hotspots that provide numerous ecosystem services such as water purification, flood control and climate change mitigation due to their capacity of sequestering carbon and modulating the atmospheric concentrations of greenhouse gases. Despite their ecological and economic importance, wetlands are disappearing at an alarming rate, and are among Europe’s most endangered ecosystems, with less than 20% remaining in good ecological condition. WET HORIZONS will provide the critical flying start for the challenge of enhancing wetland restoration using a holistic approach. It will boost crucial wetland knowledge and develop sound tools and approaches for fast-tracking large scale restoration action. The project will improve the current data available from pristine, drained and rewetted peatlands, floodplains, and coastal wetlands, model the effects of typical restoration measures under variable conditions, and analyze the potential socio-economic impacts, finally delivering guidelines and best management practices. WET HORIZONS will involve citizen science for data collection and will develop digital tools for upscaling wetland restoration including an app for the visualization of wetland status and a decision support system for policy makers. This will enable to choose best pathways in wetland restoration minimizing trade-offs, including hotspot priority lists where the ecological and biodiversity benefits are greatest with minimum investment. The results will be available in open access repositories to maximize their use and outreach. There will be a constant dialogue with policymakers and stakeholders before, during and after the project, to ground-truth the findings and ensure that the tools support country-specific decision-making processes. The results of the project will be used to promote feasible and more ambitious legislation towards protecting and restoring European wetlands to increase benefits for climate and biodiversity.

Keywords: ecosystems,climate change,wetlands,peatlands,ghg,modelling,ecosystem services