Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Venice's Nissology. Reframing the Lagoon City as an Archipelago: A Model for Spatial and Temporal Urban Analysis (16th-21st centuries) (VeNiss)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Italy,United States
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 1499877.5
EU funding (EUR): 1499877.5
Participants: 5
Project status: SIGNED

In the historical tradition, Venice is a city without walls and gates, and hence lacking suburbs. VeNiss reverses this trope by examining the urban, political, and cultural patterns connecting the capital with the chain of over sixty islands forming its lagoon fringes. Investigation of their integral role in Venice's spatial practices establishes a ground-breaking approach for the study of historic cities' margins as connective tissues, a subject seldom tackled by urban scholars. Reframing Venice within its archipelago, this project addresses that gap and explores the impact of urban edges on city planning, economic dependence, social responsiveness, and artistic production. From the 16th century, Venice became critically conscious of the granular nature of its hinterland, constructing a governance that involved the islands. Lagoon sites were systematically included in the network of capillary infrastructures for the city's supply, defence, and healthcare as well as civic rituals. Cultural entanglements sometimes bypassed the city, as novel lagoon architectural solutions permeated the Italian Peninsula through the agency of religious communities. Maps, atlases, and books of islands published on and in Venice helped consolidate the capital's archipelagic thinking into a coherent framework. VeNiss sheds light on this physical and theoretical construct –abruptly interrupted by the fall of the Venetian Republic (1797)– through a holistic project which combines social history, architecture, art and literary studies with advanced digital technologies. Coupling close archival readings with modelling systems, it proposes a pioneering methodology to reconstruct the islands' transformations alongside their interwoven relationships in a geographically- and temporally-based digital environment. VeNiss will constitute a crucial contribution to Venetian history while providing a valuable model for future urban studies seeking to visualise dispersed places through time and space.

Keywords: urban history history of venice digital heritage reconstruction digital knowledge representation
Solidarities and migrants' routes across Europe at large (SOLROUTES)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Italy
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-02-01
End date: 2028-01-31
Duration (months): 60.0
Total project cost (EUR): 2498653.75
EU funding (EUR): 2498653.75
Participants: 1
Project status: SIGNED

Unauthorized migration has always been a contentious issue in the EU. Yet, many of the policies adopted thus far have proved ineffective in containing arrivals and blocking circulations of migrants and refugees within the EU. Furthermore, unauthorized migration has continued to challenge EU borders even during the pandemic. SOLROUTES’ core research question is: how can the turbulence, persistence, and intensity of unauthorized movements and of the production of migrants’ routes across “Europe at Large” – originating from the externalization of EU borders to non-EU countries – be understood? The project addresses this challenge from an innovative angle, through an ethnographic exploration of the nexus between unauthorized movements and the networks of solidarity with migrants in transit, which involve actors and practices that have been addressed just recently in migration studies. This will be achieved by exploring and observing 50 crucial nodes in migration routes within Europe, in selected countries on its fringes (Turkey, Tunisia, Morocco) and in the Outermost Regions of the EU (French Guiana, Mayotte). SOLROUTES will aim to: a) explore the functioning, articulations, and representations of local and trans-local networks which share shelter, knowledge and resources with migrants in transit; b) assess how routes are continuously reshaped by the encounter between unauthorized movements and solidarity networks; c) develop a large-scale multi-sited ethnographic approach based on live and collaborative methods and digital research; d) develop an innovative theory in migrations studies on the nexus between solidarity with migrants in transit and unauthorized movements, contributing to structure the emerging perspective of solidarities studies; e) generate Special Features – a web series, an art exhibit, a graphic novel – linked to the research, offering new narratives for policy makers, local communities, and other relevant audiences in the spirit of public sociology.

Keywords: borders,solidarity,ethnography,visual sociology
Next-generation Enzymes and Technology for Flow Advanced Processes (NET4FLOW)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Netherlands,Brazil,Uruguay,Serbia,Germany,Argentina
Call: MSCA Staff Exchanges 2024 (HORIZON-MSCA-2024-SE-01, 2024)
Start date: 2025-11-01
End date: 2029-10-31
Duration (months): 48.0
Total project cost (EUR): 814482.86
EU funding (EUR): 741480.0
Participants: 11
Project status: SIGNED

NET4FLOW Advanced Processes focuses on the development and application of highly optimized enzymatic and other catalytic cutting-edge technologies for the efficient and sustainable production of chemicals using continuous-flow reactors. These advanced processes aim to improve productivity, with reduced waste generation and lower energy demand, by integrating new (chemo)biocatalysts with flow systems and innovative process engineering. This integrated approach seeks to reduce the environmental impact of chemical production, making it greener and more resource-efficient, in line with the objectives proposed by European Green Deal, UN Sustainable Development Goals and broader sustainability objectives in industry. By combining next-generation catalysts, advanced reactor technologies, and flow-based production, the aim is to create high-performance, low-waste, and energy-efficient chemical synthetic processes. Achieving industrial-scale solutions requires interdisciplinary and intersectoral collaboration across fields. Thus, enzyme technology, catalysis, flow chemistry, and process engineering are hot areas that may get engaged in solving sustainability issues for the transition to a climate neutral world. This joint effort between European and Latin American research institutions will pave the way for new and strong alliances to optimize enzyme-based processes and catalysts as well as for transitioning innovative technologies into sustainable, large-scale industrial applications. By leveraging the diverse expertise of this project consortium, formed by enzyme engineers and technologists, chemists, flow chemistry specialists, as well as industry partners, the research will bridge the gap between academic discovery and real-world solutions, fostering the adoption of greener, more efficient manufacturing processes.

Keywords: flow chemistry biocatalysis green chemistry sustainable processes protein engineering
Beyond Thalidomide: The Patient as an Agent of Change (BT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1499743.0
EU funding (EUR): 1499743.0
Participants: 1
Project status: SIGNED

Beyond Thalidomide will trace the historical rise of patient engagement with drug related disability through the second half of the twentieth century to understand how a novel empowered group transformed conceptions of (reproductive) health and disease in science and society. The project will map the conditions in which patient became engaged with antenatal drug use, and reconstruct how their action has created political and scientific urgency since 1960. This multifaceted engagement resulted in clashes of expertise that connected actors in the ‘Global South’ and ‘North’, from Latin American countries through Central Africa, India, and Europe, and the enforcement and stabilization of the development of approaches in reproductive health in the light of the democratic and civil societal challenges they pose, beyond traditional accounts of expert-led, iatrogenic risk management. BT will address these aims trough analysis of four interlinked fields of patient engagement: 1. Monitoring, and the surveillance of exogenous factors for birth defects 2. Prevention, and the management of risks of antenatal drug use in health care systems 3. Marketing, and the making of pharmaceutical products 4. Legal Action, and court intervention Mapping these fields of acting, BT will create an ambitious digital collection of patient life stories and a comprehensive integrated record of how patients engage. BT will, or the first time, deliver a global history of drug related disability ‘from below’, which examines the shifting contours of ‘patients’ as actors. This project takes a ground-breaking approach to the historiography of reproductive health, combining high-impact global case studies with innovative research tools to explore the political, ethical and social challenges of this alternative perspective.

Keywords: pharmaceuticals drugs disability patients health activists global health teratogen,teratology,reproductive health,environmental health,birth defects
NEXT generation of over 25MW offshore wind Turbine rotor design (NEXTgenT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark,France,Netherlands,Norway,Germany,Belgium,Spain,United Kingdom
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2024-09-01
End date: 2028-08-31
Duration (months): 48.0
Total project cost (EUR): 3177316.8
EU funding (EUR): 3177316.8
Participants: 17
Project status: SIGNED

The rated capacity of Offshore Wind Turbine (OWT) will increase continuously exceeding 25MW (over 300m rotor diameter) in the next ten years based on the current OWT industry design trends. However, there are no extant studies investigating the limits of current technologies and theories to design and analyse very large OWT systems. Furthermore, it requires further development of simulation tools, control concepts, and design and operation methods. Another important aspect of designing very large OWT rotor is the need for highly skilled human resources. For this transition, in-depth knowledge and cross-platform training are needed to train a pipeline of young engineers for the high-value jobs supporting the wind turbine system Original Equipment Manufacturers (OEMs) and wind farm development and operating industry. It is the main reason we design a doctoral training network (NEXTgenT) consists of world-leading academic beneficiaries and world-leading wind industries and research institutions as associated partners from different countries to provide the highly trained 11 PhD fellows with both continuous and discrete customized training activities through network-wide and JTN training events. The training program will be completed by secondments to encourage complementary technical exchanges and human mobility. NEXTgenT focuses on the four most important elements to design over 25MW (25+MW) OWT rotor systems: 1) wind characteristics and resources, 2) aerodynamics, 3) structures, and 4) aeroelasticity. The fellows will undertake individual projects in these areas. All the research questions in the project reflect industry needs. Academic novelty and innovation will be reflected in the methodologies and solutions. The research results will be disseminated directly to the public and scientific community. The outcomes are both technologies and a talent pool to accelerate the next generation of large-scale offshore wind power.

Keywords: wind turbine rotor system design,training,wind characteristics,aerodynamics,structures,aeroelasticity,oandm,innovation,next generation of wind turbine rotor system,industry application
Space4Earth (S4E)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: France
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-09-04
End date: 2024-10-03
Duration (months): 13.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

GlobeEye provides a new, unique, and complete perspective on global economic, environmental, and social developments. Leveraging frontier technologies in space data and artificial intelligence, it delivers valuable insights for decision-makers in finance, business, and government. It contributes to overcoming out time’s major challenges, and arguably humanity’s greatest threats, of climate change, biodiversity loss, and natural capital depletion. In particular, GlobeEye is focused on developing next generation sustainability (ESG) metrics. Thanks to state-of-the art deep learning models, it combines satellite data with a vast range of remote sensing, ground-based, alternative, and observational data to generate unprecedented information sets and predictions. The result is independent, verifiable and actionable sustainability (ESG) indicators. ESG indicators have vast possible applications, both in the private and in the public sector, but are most crucial for green finance. By providing reliable data, GlobeEye enables and supports the transition towards green finance and sustainable investment decisions, risk management, and related regulatory efforts. Our Space4Earth proposal highlights how the Women Tech EU programme can GlobeEye step up to the next stage of growth and how it comes at the perfect time for our development stage. The programme provides the needed funding, coaching and contacts to take the business planning and management steps to prepare the start-up for the next phase of funding and growth.

Keywords: sustainability,sustainable development,sustainable growth,climate change,green finance,green growth,artificial intelligence,satellite data,leadership,planning,diversity
Discovering Education in Communities of Digital Musical Instruments (DECODMI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-03-03
End date: 2027-09-02
Duration (months): 30.0
Total project cost (EUR): 235737.6
EU funding (EUR): 235737.6
Participants: 2
Project status: SIGNED

This project lies at the intersection of the disciplines of music, technology and education. It focuses on digital musical instruments, investigating current approaches for teaching the design of new musical interfaces in professional and higher education contexts. The research will identify, compare, and critically assess teaching practices by engaging music technology educators and organisations through surveys, interviews and fieldworks. The fellowship will produce a first broad and systematic analysis of instrument design education, across academic and non-academic sectors. In addition, the project will advance art-technology disciplines by providing practical accounts and accessible resources on best educational practices, combining technology innovation with socio-cultural awareness, diversity and inclusion. DECODMI aims to examine art-technology education to better understand the modalities through which cultural values are being transmitted within different communities of practices, allowing us to ask what alternatives might exist, and develop resources that could facilitate the circulation of knowledge, methods and tools across disciplines, sectors and cultural contexts. The project will be hosted at InfoMus (University of Genoa): a research centre specialised in the development of interactive multimodal systems for the arts and wellbeing; under the supervision of Prof. Antonio Camurri, a leading scholar in the fields of affective and creative computing, with extensive experience in music technology education. The fellow, Dr. Giacomo Lepri, is a prominent musician with an extensive interdisciplinary academic record merging composition and performance, human-computer interaction, and technology studies, whose research focuses on the socio-cultural implications of instrument design. The fellowship will also feature a placement at CHAIR, a German company conducting research on haptics and audio interaction design.

Keywords: digital musical instruments,art technology education,science and technology studies,music anthropology music performance and composition
Autologous engineered neural tissue as a novel therapeutic for spinal cord injury (MatriSpine)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Spinal cord injury (SCI) occurs upon disruption of spinal cord axon nerves, leading to motor, sensory, and autonomic loss below the level of injury. Yet, no therapeutic agents have been found to show significant benefits. Matricelf has developed a novel therapeutic agent, in the form of autologous engineered neural tissue intended to be surgically transplanted at the site of SCI, designed to regenerate injured spinal cord. Matricelf neural tissue is an entirely autologous cell therapy product comprised of induced pluripotent stem cells (iPSCs)-derived neural cells differentiated within an extracellular matrix (ECM)-based hydrogel to form mature, patient-specific functional neural tissue. In vitro studies demonstrate both functionality and safety features of the engineered neural tissue. Preliminary in vivo feasibility studies in a chronic SCI mice model indicate promising signs of efficacy of the engineered neural tissue. We hypothesize that the autologous engineered neural tissue will promote injured spinal cord regeneration while minimizing the risk of tissue rejection and will restore lost motor and sensory functions.

Keywords: neural implants,autologous spine implants,personalized medicine
A novel vaccine approach to treat cancer (CanVax)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 48.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

CimCure is a Dutch biotech company developing a first-in-class, tumor vasculature targeting vaccine CVx1 that has the potential to treat most, if not all, solid tumors. CVx1’s uniquely targets the tumor vasculature by inducing a polyclonal antibody response against extracellular vimentin (eVim) leading to starvation and shrinkage of the tumor and, eventually, in full disappearance of the tumor lesion. CVx1 has shown proof-of-concept safety and efficacy in multiple mouse cancer models, as well as in a clinical study in dogs (doubling survival). Thus far, CimCure has raised +€8M and needs an additional €2.5M of the EIC grant to conduct a phase 1b/2a clinical trial in Ewing Sarcoma. This will help securing additional financing (including €5M of EIC equity) for a further phase 2b trial, regulatory approvals and market launch in Q42028.

Keywords: conjugate vaccines,cancer vaccines,anti angiogenesis,solid tumors,tumor vasculature,polyclonal antibody response,humoral immunity,ewing sarcoma
Learning the dynamic statistical folding of bacterial chromosomes (Learn4DChromosome)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Condensed Matter Physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-05-01
End date: 2029-04-30
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

The physical organization of bacterial chromosomes is inherently variable, with large conformational fluctuations both from cell to cell and over time. Yet, chromosomes must also be structured to facilitate processes such as transcription, replication, and segregation. A physical description of this dynamic statistical folding of bacterial chromosomes remains largely elusive. Hi-C experiments probe chromosome organization by measuring average contact frequencies of chromosomal loci pairs. Despite the rapidly expanding database of high-resolution Hi-C data for many bacterial species and conditions, these data are still mainly interpreted on a case-by-case basis and with qualitative or heuristic methods. My goal is to develop a principled unifying approach to infer and analyze the dynamic organization of chromosomes from bacterial Hi-C data. This data-driven approach aims to unravel the dynamic statistical folding of chromosomes – and its impact on functional processes – in growing and replicating bacteria. We will infer a bacterial chromosome model from state-of-the-art data using learning methods at the intersection of information theory and statistical mechanics. By combining data-driven with mechanistic modelling approaches, we aim to: •Decode information contained in Hi-C data by learning both 3D steady-state and 4D dynamic models for the statistical organization of chromosomes. •Provide a unifying statistical mechanics analysis of the dynamic statistical folding of chromosomes across bacterial species under both steady-state and replicating conditions. •Develop theoretical methods using pairwise and multi-contact statistics to study the topology of statistical chromosome folding. My research will advance the field by providing a conceptual understanding of the physical and mechanistic principles that underlie chromosome organization in developing bacteria. This work could shed new light on vital functional processes such as chromosome segregation.

Keywords: chromosome organization,physics of bacteria