Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Development of antibacterial MetAllic Glass mICrofibers (MAGIC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2023-09-19
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: SIGNED

The proposed training-through-research aims to develop novel antibacterial materials for medical devices based on Zr-Cu-Ag metallic glasses in the form of microfibers. The major cause of metal implants retrieval is infection due to bacterial biofilm formation on their surface. Many studies have been conducted on the development of antibacterial coating on metallic implants, but evidence has shown numerous drawbacks associated with coatings including their lack of durability. “MAGIC” project proposes the development of Zr-Cu-Ag metallic glasses with generic and intrinsic antibacterial properties which makes them capable of battling antibiotic resistance bacterial infection with no further required coating. Meaningful development of this novel class of intrinsic antibacterial metals requires a fundamental understanding of their antibacterial mechanism which to date is not well-understood. Therefore, “MAGIC” project fundamental ambition is to discover the underlying antibacterial mechanism of innovative Zr-Cu-Ag metallic glasses though a novel interdisciplinary approach, combing materials engineering knowledge of metallic glasses with advanced biological analysis of bacteria. On the engineering side, the main antibacterial contributors “chemical composition” and “surface energy” of Zr-Cu-Ag metallic glass will be modified and controlled; On the biological analysis side, bacterial genetic and metabolic response to these changes will be studied by coupling basic metabolic assays with next-generation sequencing and omics techniques. Furthermore, to facilitate the integration of antibacterial metallic glasses in the medical industry, “MAGIC” has an applied ambition to fabricate the best found Zr-Cu-Ag metallic glass (in terms of chemical composition and surface energy) in the form of microfibers for the very first time. Microfibers have higher surface areas and are easier to be formed into different shapes, offering added value to their applicability in industry.

Keywords: material science,alloy,metallic glass,microfiber,antibacterial material,antibacterial mechanism,bacterial analysis,gene sequencing,metabolic assay,omics techniques,surface energy,corrosion
Retro Propulsion Assisted Landing Technologies (RETALT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling European competitiveness, non-dependence and innovation of the European space sector
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Germany,Switzerland,Portugal
Call: Access to space (H2020-SPACE-2018, 2018)
Start date: 2019-03-01
End date: 2022-08-31
Duration (months): 42.0
Total project cost (EUR): 2995958.75
EU funding (EUR): 2995958.75
Participants: 6
Project status: CLOSED

For Europe’s non-dependence, access to space is crucial. To foster the European industry competitiveness, the costs of the European launch systems need to be reduced and flexibility needs to be improved. The development of reusable launch vehicle (RLV) is currently changing the global market of space transportation systems and is promising immense cost savings. The only operational approach of RLV to date is the Vertical Take-off Vertical Landing launcher (VTVL), which is decelerating by firing its engines against the velocity vector, the so called retro propulsion. The know-how in the technologies of retro propulsion assisted landing in Europe is spares. In this project we aim to investigate and developed these technologies. Therefore, the two main scientific and technological objectives of the RETALT project are: • To investigate the launch system reusability technology of VTVL TSTO (Vertical Take-off Vertical Landing - Two Stage To Orbit) by applying retro propulsion combined with aerodynamic control surfaces that is currently dominating the global market. • To investigate the launch system reusability technology of VTVL SSTO RLV (Vertical Take-off Vertical Landing - Single Stage To Orbit) applying retro propulsion for future space transportation systems. To meet these two main project objectives of the project, described above, two reference launch vehicle configurations will be defined: • A configuration similar to the SpaceX rocket “Falcon 9” that will be the reference for the state-of-the-art TSTO RLV. • A configuration similar to the DC-X that will serve as a reference for a VTVL SSTO.

Keywords: reusability,retro propulsion assisted landing,stability and gnc,hot plume,base interaction,ground demonstrators
Quantum Simulation on a Photonic Chip (QUCHIP)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Emerging themes and communities
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Germany,Italy,Belgium,United Kingdom,United Kingdom,United Kingdom
Call: Quantum simulation (H2020-FETPROACT-2014, 2014)
Start date: 2015-03-01
End date: 2018-02-28
Duration (months): 36.0
Total project cost (EUR): 2681713.75
EU funding (EUR): 2681713.75
Participants: 9
Project status: CLOSED

Simulation is a fundamental computational tool for modern science with applications ranging from drug design to materials science. Quantum simulators have the potential to revolutionize the way simulations are performed by accessing system sizes that are untractable in classical machines. As a result, they will become a suite of powerful and precise instruments enabling the investigation of relevant phenomena in the dynamics of complex quantum systems, such as quantum transport and energy transfer, as well as implementing quantum improved computation - tasks hard to simulate classically. QUCHIP aims at implementing quantum simulation on integrated photonic processors. Photons present unique advantages deriving from their mobility and the immunity to decoherence: these two features make them substantially different from any other quantum system. Moreover integrated quantum photonics capitalizes on the multi-billion dollar investment already placed into photonics development and commercialization. QUCHIP will exploit these advantages to implement quantum walk experiments in which several photons propagate over complex circuit architectures “jumping” between different waveguides. This platform represents the most resource-efficient quantum computation scheme to date: Boson Sampling. Recent computational theory findings have shown exceptional potential for this scheme to achieve the quantum supremacy regime in which quantum systems surpass classical ones. QUCHIP will develop new photonic technologies, ranging from on-chip sources of single photons to complex waveguide architectures and on-chip detectors. We will explore the dynamics of noisy quantum networks and develop practical schemes to demonstrate key structural and functional elements of the network dynamics. The benefits range from insights into the dynamics of complex systems to a dramatic push forward for the realization of an experimental device whose output cannot be formally calculated by classical means.

Keywords: integrated quantum photonics,quantum walk,optical simulator,on chip manipulation of light,quantum supremacy
Elusive enzymes with biocatalytic potential: chlorinases in the plant kingdom (CHLOROIRIDOIDS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-12-01
End date: 2017-11-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

A plethora of halogenated natural products documents the existence of halogenases in plants but the responsible enzymes remain elusive. Chlorinated iridoid glycosides, for instance, occur in Phlomis, a genus in the mint family. Based on knowledge of iridoid biosynthesis and a mechanistic hypothesis for the chlorination reaction, we aim to discover the underlying enzymes. We will sequence transcriptomes of Phlomis tissues in different metabolic states, identify homologs of enzymes involved in iridoid biosynthesis, and search for candidate genes showing similar expression patterns. Among these candidates, the chlorinase will be identified by assaying the reactivity of heterologously expressed protein in vitro. Biochemical and structural characterization of the chlorinase will clarify whether chlorine incorporation proceeds via a rare epoxide opening mechanism. The level of chloroiridoid production will be assessed in plants after silencing the chlorinase, in order to confirm the metabolic role of the newly discovered enzyme. Furthermore, transient expression in plants providing structurally diverse precursors will reveal whether chlorinated natural products can be made that are new to nature. The discovery of a chlorinase in higher plants will fill an important gap in our understanding of plant secondary metabolism. Given the potential of chlorine for enhancing protein-ligand interactions, such enzymes would become useful tools for biocatalysis and the engineered biosynthesis of natural products with fine-tuned medicinal properties.

Keywords: chlorinase,iridoid,comparative transcriptomics,gene discovery,lamiaceae
AN INNOVATIVE BUSINESS MODEL FOR A USER–CENTRIC DECISION SUPPORT SYSTEM TO INCREASE AND SUPPORT ELECTRIC VEHICLES UPTAKE (CleanPEA)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: SME instrument
Countries involved: United Kingdom
Call: SME business model innovation (H2020-SMEINST-1-2015, 2015)
Start date: 2015-12-01
End date: 2016-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The main objective of this innovation project is to refine, scale up and bring to market readiness a user-centric ICT decision support system (CleanPEA) that makes use of an innovate four-tier business model involving corporate fleet owners, vehicle drivers, EV manufacturers and infrastructure providers. CleanPEA will purpose it to support and encourage corporate fleet owners/operators to make the change from diesel-/petrol-powered, Light Commercial Vehicles (LCV – cars and vans) to the Electric Vehicles (EVs) equivalent. This will help the EU meet its demanding CO2 emission reduction targets, as cars and vans contribute around 15% of all CO2 emissions across Europe . Fleet Innovations Ltd. (FLEET) is an ambitious, Innovative-Driven Enterprise (IDE) with a strong desire to internationalise their business and led by a team of experts and serial entrepreneurs in providing data capture/reporting technology systems and fleet management solutions to track corporate business mileage/journey data. While engaging in customer building activities for our current solution (PEAK Miles), we discovered a strong desire among commercial corporations with company LCV fleets to switch to EVs as a way of cutting their cost and meeting their carbon reduction obligations . Europe’s corporate fleets produce around 380Mt CO2 emission annually, accounting for around 8% of all EU emissions . We have conservatively estimated that the successful commercialisation of CleanPEA will allow us to generate new cumulative revenues and profits respectively of €94.32m and €57.55m (EBITDA) 6 years post project (2022). As a result, we would create 91 new jobs across Europe and directly contribute to the reduction of CO2 emissions by 609,780 tonnes.

Keywords: user centric decision support system for the uptake of electric vehicles,four tier business model delivering and capturing value for a wider network community using the network effect
Easy open access dissemination for research institutions (Polaris)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Luxembourg
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-08-01
End date: 2016-12-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Research institutions in EU and globally are under-equipped with tools to share and disseminate their research effectively, to manage and increase the efficiency of their research communication activities and to track their performance. They spend large amounts of money on annual journal subscriptions (€100k + per year, given average prices for 15 top journals of €1,000+ per year). While getting scarce funds sucked out to finance pay-per-download closed-access publishing systems, research institutions have difficulty transitioning to open access approach, which is becoming a requirement in many cases, especially for research funded by public money. Polaris is the first comprehensive turnkey repository solution for research institutions that allows them to self-archive all of their scientific material, increase their visibility to researchers both inside and outside, and communicate effectively to different groups, including the general public. Polaris comes with an easy-to-use interface, collaborative and social networking features, and is integrated into the www.mysciencework.com global network of 30M+ articles and 500k+ researchers and industry contacts worldwide. Polaris disrupts existing closed-access scientific publishing systems by giving research institutions their own open access publishing platform. It provides the scientific community, industry and general public with better access to research, which has an immediate impact on scientific progress and on society in general. Polaris is developed by MyScienceWork, an innovative SME from Luxembourg, founded in 2010, that previously delivered www.mysciencework.com. In 2016 Challenge magazine named MyScienceWork as one of the best 100 companies to invest in. Polaris has been pre-validated by 15 institutions in different market segments. This feasibility study will run a market assessment and validation of the Polaris business model in 3 key market segments, to ensure its wide adoption.

Keywords: open access,dissemination,publishing platform
The first ultra-low extractable silicone film release liner for electronics, silicone adhesive market and medical applications (XIMOFILM)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-08-01
End date: 2018-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Today, silicone contamination is one of the main challenges for players of the electronics sector which require the use of Pressure Sensitive Adhesives (PSA). Silicon contamination can drive to 10-20% of defective products. The release liners used for this PSA require low levels of extractible silicone (<20 ng/cm²). Besides, the adhesives used in the electronic market are solvent based. Today, solvent resistant release liners present still high levels of extractible silicone. On the other hand, those release liners with low extractible silicone are not solvent resistant and often do not present high subsequent adhesion. XIMOFILM is also a release liner addressed to the medical sector, where silicone and soft silicone gel adhesives are increasingly used. In this sector the release liners must also present low level of extractible silicones. Founded in 2001, CPI is a spin-off French pioneering company offering complete service for industrial atmospheric plasma integration addressed to professionals of packaging, printing, polymer transformations and textiles. Thanks to the optimisation and industrialisation of our cold atmospheric plasma technology, CPI will offer the first ultra-low extractable film silicone release liners with good release force properties (low) and high subsequent adhesion of the adhesive (more than 90% compared to 65% of current competitors), solvent resistant and with very low silicone contamination (<10ng/cm²). The production cost will be also reduced, allowing to purchasing prices 30% cheaper than our competitors. For this Phase 1, we will focus on the technical and financial feasibility of XIMOFILM process and well define the business model to extend our commercial network to Europe and Asia. For CPI, this project will imply a ROI of 9% in 2024. For end users, XIMOFILM will represent an opportunity to reduce damaged final products due to silicone which would save them up to 15% due to after sales services and wasted devices.

Keywords: hard disk drivers,cover lay,electronics,medical market,silicone adhesive market,release liner
Anti-Crash lightweight fuel bladder Tank Integrated on a new RotorCraft (ACTIonRCraft)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: France
Call: Fuel bladder tanks for a fast compound rotorcraft (H2020-CS2-CFP02-2015-01, 2015)
Start date: 2016-06-20
End date: 2020-12-19
Duration (months): 54.0
Total project cost (EUR): 1250163.75
EU funding (EUR): 800000.0
Participants: 1
Project status: CLOSED

ACTIonRCraft will design, develop, manufacture, verify and validate [qualification tests (leakproofness, temperature, pressure, fluid susceptibility, mechanical and drop tests) up to flight tests] five qualified anti-crash lightweight fuel bladder tanks which will integrate for the very first time ZODIAC AEROSAFETY SYSTEMS (ASY) robust, light and ecofriendly technological breakthrough (functionalized liner, lighter fabric and solvents without pictogram). Fully supporting the rapid emergence of the highly performant rotorcraft, this next generation of anti-crash lightweight fuel bladder tanks with limited environmental footprint will demonstrate a weight reduction of 15%, a reduction of 80% of VOC emission during sustainable manufacturing, conformance with CS29 and mechanical properties at the highest level (sealing, resiliency, service temperature and crash resistance). ACTIonRCraft will be carried by ASY who has the required specific expertise in fuel bladders tanks (i.e. project/program management, design, development, manufacturing, installation and support to flight tests) with a proven track record of successful R&T projects, collaborative RTD projects (ESCOTHp, GENOME, COMAIT, CleanSky 1, etc. ) and R&D programs (e.g. H160 – X4, EC175, EC225, etc.). Notably, a first step on tank walls weight improvement was already achieved by ASY within the H160 program and ASY has already developed the necessary technological breakthrough today at TRL4 (functionalized liner, lighter fabric) and at TRL5 (Solvents without pictogram) to be accessed and used in ACTIonRCraft. Also, ASY is the unique EU fuel systems provider approved by aviation authorities worldwide since several years, owning Design Organization Approval (DOA), Production Organization Approval (POA) and Maintenance Organization Approval (MOA).

Keywords: fuel tank bladders,anti crash,lightweight,innovative materials,liner,fabric,solvents,high speed rotorcraft lifercraft,low voc emission,mechanical properties,back up solution
Market maturation of CleanTechBlock technology (CLEANTECHBLOCK2)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Denmark
Call: Boosting the potential of small businesses in the areas of climate action, environment, resource efficiency and raw materials (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2017-06-01
End date: 2019-05-31
Duration (months): 24.0
Total project cost (EUR): 1572500.0
EU funding (EUR): 1100750.0
Participants: 1
Project status: CLOSED

Clay bricks are one of the preferred building materials in Europe, but they are facing numerous threats due tightened regulations on buildings’ energy and raw material consumption levels and CO2 emissions. These threats together with market trends such as increasing environmental conscience, preference for green materials and an excellent clay bricks’ public image creates a major market opportunity that Gråsten Brickworks (GB) aims to pursuit through the development of an innovative building component which will enable a paradigm change within the construction market and recycling in Europe. GB vision is to take the final steps of commercial and technical development and product maturation towards the commercialization of CleanTechBlock (CTB) – a patented multifunctional sandwich-block based on the combination of two clay brick shells and foamed recycled glass. CTB’s advantages over bricks are compelling as the insulation, strength properties and construction price are similar and it offers: an overall increase in the living area (3-5%), a reduction in the overall house wall construction time (5x faster), while reducing maintenance requirements and transportation costs. It also contributes to the mitigation of environmental problems due to an increase of glass waste recycling, decrease of raw material (clay) and energy consumption and CO2 emissions. CLEANTECHBLOCK2 project is expected to significantly enhance the profitability and competitiveness of GB, with an expected sales turnover of €67M and profits of €15M, 6 years after commercialization in the environmentally conscious construction segment (both residential and non-residential) of primary targeted markets – Denmark, Sweden and Germany. Besides giving to GB a technological leap with the consequent competitive advantage and export potential, CLEANTECHBLOCK2 will assist Europe in achieving objectives for environmental and energy policy.

Keywords: construction material,sandwich block,clay,foamed recycled glass,environmental,sustainability,thermal insulation