Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Bio-based strategies and roadmaps for enhanced rural and regional development in the EU (BE-Rural)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable and competitive bio-based industries and supporting the development of a European bio-economy
Action type: Coordination and support actions
Countries involved: Germany,Germany,Bulgaria,Romania,Croatia,Poland,Latvia,United Kingdom
Call: Realising the potential of regional and local bio-based economies (H2020-RUR-2018-1, 2018)
Start date: 2019-04-01
End date: 2022-07-31
Duration (months): 40.0
Total project cost (EUR): 2996288.75
EU funding (EUR): 2996288.75
Participants: 9
Project status: CLOSED

The overall goal of BE-Rural is to realise the potential of regional and local bio-based economies by supporting relevant actors in the participatory development of bioeconomy strategies and roadmaps. BE-Rural will investigate the particular characteristics of the selected regions at a macro level, as well as existing best practices and business models geared towards the bioeconomy. This higher-level analysis will aid in the assessment of the 'bioeconomy potential' of the selected regions. This work will set the foundation for the implementation of a series of regional Open Innovation Platforms to kick-start the co-creation process, bringing together key stakeholders from academia, policy, business and civil society to develop ideas and capitalise on this bioeconomy potential. Activities will include research & innovation capacity building workshops, educational seminars and webinars, summer schools, and Bio-based Pop-up Stores. Building from this, the proposed 'Network of Knowledge' will aim to share knowledge and lessons learned from the Open Innovation Platforms at an inter-regional level, further disseminating best practices, closing the information gap on issues related to sustainability, and increasing capacities of regional authorities and stakeholders.

Keywords: bioeconomy,regional policy,co creation,sustainability,business models,bio based value chains
New paradigms for correlated quantum matter: Hierarchical topology, Kondo topological metals, and deep learning (PARATOP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Switzerland
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-01-01
End date: 2023-09-30
Duration (months): 69.0
Total project cost (EUR): 1362401.0
EU funding (EUR): 1362401.0
Participants: 1
Project status: SIGNED

Discovering, classifying and understanding phases of quantum matter is a core goal of condensed matter physics. Next to the notion of symmetry breaking phases, the concept of topological phases of matter is a prevailing theme of recent research. Topological phases are envisioned for various applications due to their universal and robust properties, such as protected conducting boundary modes, and provoke fundamental questions about the nature of many-body quantum states by providing the basis for exotic quasiparticles. In this ERC research project, I propose several new topological phases and novel numerical approaches for studying and classifying the most sought-after topological phases of matter. Concretely, I propose the concept of three-dimensional hierarchical topological insulators, which, in contrast to the known topological phases, do not posses gapless surface, but protected gapless edge modes. Moreover, I plan to study topological metals arising in strongly correlated Kondo systems, going beyond the current paradigm of considering topological metals that arise in the absence of electronic correlations. Furthermore, I propose to make the analogous step for topological superconductors, which have been studied as free models to search for Majorana quasiparticles: For the first time, I want to explore strongly interacting systems that realize the more powerful parafermion quasiparticles with numerical techniques. Finally, in a cross-disciplinary and exploratory sub-project, I will employ methods of deep neural networks to classify strongly correlated quantum phases using supervised learning combined with a technique called deep dreaming. Each of these sub-projects has the potential to make a paradigm-changing contribution to the study of strongly correlated and topological states of quantum matter and the combination of them allows to take advantage of synergy effects and a balance between high-risk and definitely feasible key developments.

Keywords: topological insulators,topological semimetals,fractional quantum hall effects,disordered systems
Plug-in Electric System to Cut Emissions on Transportation (ADDPLUGIN)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Portugal
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2019)
Start date: 2020-03-01
End date: 2022-10-31
Duration (months): 32.0
Total project cost (EUR): 2411235.0
EU funding (EUR): 1687864.5
Participants: 1
Project status: CLOSED

AddVolt is a technology-based Start-Up responsible for the World’s First Plug-in Electric system which eliminates the van, truck, trailer and reefer container’s diesel usage. Our patented solution is an intelligent, non-invasive and cloud-connected device that recovers energy during braking and truck’s slowdowns (regenerative braking), stores it and powers the vehicle’s auxiliary units such as refrigeration units and lifts gates, emulating the power grid, reducing the trucks fuel consumption and dependence on secondary diesel engines. There are 1.1 million refrigerated trucks in Europe and over 4 million worldwide . The reduction in fuel consumption in the Heavy-Duty Vehicle´s (HDV) refrigeration unit allows for direct cost savings of 87-100% in fuel expenditure and an equivalent reduction in the CO2 emissions (demonstrated in real use cases). The reduction of operating noise and the reduction of maintenance costs associated with the extended vehicle life-cycle are also important benefits to be considered. Furthermore, the economic and environmental benefits of AddVolt solution comply with the EU goals of transitioning to a low-carbon economy. AddVolt’s technology is taking a step forward to the electrification of the transport sector, being able to work alongside with fully electric vehicles, increasing their capacity and autonomy.

Keywords: plug in electric kit,electric vehicles,refrigeration units,heavy duty vehicles,fuel saving,emissions reduction
FIber-Wireless Integrated Networks for 5th Generation delivery. (FIWIN5G)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Spain,Italy,Germany,Spain,Italy,Israel,Cyprus,Hungary,Slovenia,Hungary,Slovenia,France,France,France,Denmark,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 3867896.88
EU funding (EUR): 3867896.88
Participants: 20
Project status: CLOSED

This European Training Network aims to produce the next generation of early stage researchers who will enable Europe to take a leading role in the development of future devices, systems and networks supporting the 5G high-speed wireless internet. To do this, researchers must be able to work in interdisciplinary teams, integrate their activities, share expertise, and promote a vision of a converged wireless and optical devices and networks that efficiently supports the services and applications being demanded. A large number of technologies and devices will need to converge, co-exist and interoperate, and most importantly, cooperate, if this vision is to be efficiently and cost-effectively realised. A key area within this next generation jigsaw is the integration of optical fibre networks and radio networks at mm-wave frequencies, to provide high-bandwidth front/backhaul services and enable scalable and manageable networks without a highly complex interface structure and multiple overlaid protocols. FIWIN5G aims to provide doctoral students with the exposure to the range of skills, necessary to address these challenging demands. Deep technical knowledge but also key transferable skills common in entrepreneurship, management, financing as well as communication, and societal outreach. While becoming expects in one particular sub-domain, they must understand the broad context of their work, whether it is systems/network engineers understanding the devices and technologies that make up the networks or device engineers understanding the networks in which their devices will function. We draw together a range of world-leading partners, selected for their complimentary and excellence to offer a vital opportunity to advance industry’s understanding and uptake of the key technologies in this area. To provide excellent training and diverse experience of research environments, all project involve a significant period of secondment and collaboration with an industry partner.

Keywords: next generation internet high capacity wireless microwave photonics optical fiber
The design and development of efficient biocatalytic cascades and biosynthetic pathways for the sustainable production of amines (BIOSUSAMIN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Netherlands,United Kingdom
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-05-01
End date: 2020-10-31
Duration (months): 66.0
Total project cost (EUR): 1497270.0
EU funding (EUR): 1461840.0
Participants: 2
Project status: CLOSED

The objective of this project is to design and develop biocatalytic cascades, using purified enzymes in vitro, as well as biosynthetic pathways in whole cell microbial organisms. These biocatalytic cascades and biosynthetic pathways will be developed for the synthesis of chiral and achiral amines that are of particular interest for the chemical industry. The amine functionality will be introduced using amine dehydrogenases (AmDHs) as biocatalysts in the pivotal core enzymatic step. AmDHs are a new class of enzymes that have recently been obtained by protein engineering of wild-type amino acid dehydrogenases. However, only two AmDHs have been generated so far and, moreover, they show a limited substrate scope. Therefore protein engineering will be undertaken in order to expand the substrate scope of the already existing AmDHs. In addition, novel AmDHs will be generated starting from different wild-type amino acid dehydrogenases as scaffolds, whose amino acid and DNA sequences are available in databases, literature, libraries, etc. In particular, protein engineering will be focused on the specific chemical targets that are the objectives of the designed biocatalytic cascades and in addition, screening for more diverse substrates will also be carried out. Finally, the AmDHs will be used in combination with other enzymes such as alcohol dehydrogenases, oxidases, alkane monooxygenases, etc., to deliver variously functionalised amines and derivatives as final products with elevated yields, perfect chemo- regio- and stereoselectivity, enhanced atom efficiency and minimum environmental impact. Such an approach will be realised through the design of new pathways that will convert inexpensive starting materials from renewable resources, encompassing the internal recycling of redox equivalents, the use of inorganic ammonia as nitrogen source and, if necessary, only molecular oxygen as the innocuous additional oxidant. Water will be the sole by-product.

Keywords: 1 biocatalysis and biotransformations 2 enzyme catalysis 3 biocatalytic cascades 4 artificial metabolic pathways
Innovative Biodegradable Poly(ionic liquid)s for Bioelectronics (iPILs4Bionics)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-09-01
End date: 2020-09-02
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Poly(ionic liquid)s or PILs are expanding classical property profiles of polymers and stirring great interest in the development of diverse areas, as green chemistry, energy, biotechnology, materials or membrane science. One of the common concerns of PILs consist of its biodegradability due their bioaccumulation and negative effects to the environment and the human body. The main goal of this project is to develop the first generation of biodegradable PILs. The most successful biodegradable polymeric backbones such as polycarbonates or polyesters will be combined with readily biodegradable cholinium-based ionic liquids. The polymers will be synthesized by controlled ring-opening polymerization using recently developed organocatalysis tools. The most promising biodegradable PILs will be investigated as ion conductive soft membranes in bioelectronic devices. This MSCA Fellowship will open the best career possibilities for the Experienced Researcher (ER), and excellent young female scientist. After a successful PhD and 2 years Post-Doc in ionic liquid-based materials and gas separation membranes at ITQB-Universidade Nova de Lisboa (Portugal), she decided to move to a different environment, where she can exploit all her materials science expertise. The Innovative Polymers Group directed by Prof. David Mecerreyes at POLYMAT-University of the Basque Country (Spain) is one of the top-class groups in the emerging area of PILs. This multidisciplinary project will broaden the scientific knowledge of the ER and help her to grow and expand her network in order to reach a future group leader position in the materials science field.

Keywords: ionic liquids,biodegradable,bioelectronics
Organisation of the EU international Bioeconomy Stakeholders Conference - Utrecht 2016 (BEU2016)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: Coordination and support actions
Countries involved: Netherlands
Call: Food (H2020-Adhoc-2014-20, 2016)
Start date: 2016-02-05
End date: 2016-11-04
Duration (months): 9.0
Total project cost (EUR): 153800.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

In order to cope with an increasing global population, rapid depletion of many resources, increasing environmental pressures and climate change, Europe needs to radically change its approach to production, consumption, processing, storage, recycling and disposal of biological resources. The Europe 2020 strategy calls for a Bioeconomy as a key element for smart and green growth in Europe. However, the complex inter-dependencies that exist between challenges can lead to trade-offs, such as the controversy about competing uses of biomass. The latter arose from concerns about the potential impact of the growing demand for renewable biological resources by other sectors on food security, the use of scare natural resources and the environment in Europe and third countries. On 13th of February 2012 the EU launched the Bioeconomy strategy and action plan on "Innovating for Sustainable Growth: a Bioeconomy for Europe", which aims to pave the way to a more innovative, resource efficient and competitive society that reconciles food security with the sustainable use of renewable resources for industrial purposes, while ensuring environmental protection. In this respect the Strategy stresses that participatory models are needed that engage citizens and end-users in order to reinforce the relationship between science, society and policy making. More informed dialogues will in fact allow science and innovation to provide a sound basis for policy making and informed societal choices by taking into account legitimate societal concerns and needs in the Bioeconomy. In this framework, and in support of the review and implementation of the strategy, this 4th Bioeconomy Stakeholders Conference on April 12-13 2016 will provided opportunity for public awareness raising and for an informed dialogue on the progress of the Bioeconomy, involving researchers, stakeholders, policy makers and the civil society at large across the whole Bioeconomy value chain.

Keywords: the 4th bioeconomy stakeholdersconference is not a stand alone event but the starting point of interactive involvement of stakeholders in the review of the bioeconomy strategy
Decoding and controlling cell-state switching: A bottom-up approach based on enhancer logic (cis-CONTROL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Belgium
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-06-01
End date: 2023-05-31
Duration (months): 72.0
Total project cost (EUR): 1999660.0
EU funding (EUR): 1999660.0
Participants: 1
Project status: SIGNED

Cell-state switching in cancer allows cells to transition from a proliferative to an invasive and drug-resistant phenotype. This plasticity plays an important role in cancer progression and tumour heterogeneity. We have made a striking observation that cancer cells of different origin can switch to a common survival state. During this epigenomic reprogramming, cancer cells re-activate genomic enhancers from specific regulatory programs, such as wound repair and epithelial-to-mesenchymal transition. The goal of my project is to decipher the enhancer logic underlying this canalization effect towards a common survival state. We will then employ this new understanding of enhancer logic to engineer synthetic enhancers that are able to monitor and manipulate cell-state switching in real time. Furthermore, we will use enhancer models to identify cis-regulatory mutations that have an impact on cell-state switching and drug resistance. Such applications are currently hampered because there is a significant gap in our understanding of how enhancers work. To tackle this problem we will use a combination of in vivo massively parallel enhancer-reporter assays, single-cell genomics on microfluidic devices, computational modelling, and synthetic enhancer design. Using these approaches we will pursue the following aims: (1) to identify functional enhancers regulating cell-state switching by performing in vivo genetic screens in mice; (2) to elucidate the dynamic trajectories whereby cells of different cancer types switch to a common survival cell-state, at single-cell resolution; (3) to create synthetic enhancer circuits that specifically kill cancer cells undergoing cell-state switching. Our findings will have an impact on genome research, characterizing how cellular decision making is implemented by the cis-regulatory code; and on cancer research, employing enhancer logic in the context of cancer therapy.

Keywords: enhancer,cell state transition,epigenomic reprogramming,gene therapy,drug resistance,wound repair,bioinformatics,cis regulatory modules,single cell,microfluidics,non coding snps
Climate dimension of natural halogens in the Earth system: Past, present, future (CLIMAHAL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Spain
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-09-01
End date: 2023-12-31
Duration (months): 76.0
Total project cost (EUR): 1979112.0
EU funding (EUR): 1979112.0
Participants: 1
Project status: SIGNED

Naturally-emitted very short-lived halogens (VSLH) have a profound impact on the chemistry and composition of the atmosphere, destroying greenhouse gases and altering aerosol production, which together can change the Earth´s radiative balance. Therefore, natural halogens possess leverage to influence climate, although their contribution to climate change is not well established and most climate models have yet to consider their effects. Also, there is increasing evidence that natural halogens i) impact on the air quality of coastal cities, ii) accelerates the atmospheric deposition of mercury (a toxic heavy metal) and iii) that their natural ocean and ice emissions are controlled by biological and photochemical mechanisms that may respond to climate changes. Motivated by the above, this project aims to quantify the so far unrecognized natural halogen-climate feedbacks and the impact of these feedbacks on global atmospheric oxidizing capacity (AOC) and radiative forcing (RF) across pre-industrial, present and future climates. Answering these questions is essential to predict if these climate-mediated feedbacks can reduce or amplify future climate change. To this end we will develop a multidisciplinary research approach using laboratory and field observations and models interactively that will allow us to peel apart the detailed physical processes behind the contribution of natural halogens to global climate change. Furthermore, the work plan also involves examining past-future climate impacts of natural halogens within a holistic Earth System model, where we will develop the multidirectional halogen interactions in the land-ocean-ice-biosphere-atmosphere coupled system. This will provide a breakthrough in our understanding of the importance of these natural processes for the composition and oxidation capacity of the Earth´s atmosphere and climate, both in the presence and absence of human influence.

Keywords: chemistry climate interactions,oxidation capacity of the atmosphere,climate