Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Art and Research on Transformations of Individuals and Societies (ARTIS)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Innovative societies
Action type: Research and Innovation actions
Countries involved: Germany,Austria,Serbia,Netherlands,Denmark,United Kingdom,United Kingdom
Call: Societal challenges and the arts (H2020-SC6-TRANSFORMATIONS-2019, 2019)
Start date: 2020-02-01
End date: 2025-01-31
Duration (months): 60.0
Total project cost (EUR): 2994276.25
EU funding (EUR): 2994276.25
Participants: 9
Project status: SIGNED

ARTIS is a first-of-its-kind collaboration to theoretically explore, empirically capture, and co-create individual and societal change via the transformative power of art. We argue that to make better policy that advances art’s efficacy, it is necessary to build a systematic program that combines empirical and theoretical research with perspectives of artists, art educators, and other art stakeholders. Our objective is fourfold. First, we will integrate state-of-the-art empirical approaches from psychology, neuroscience, and phenomenology (UNIVIE, UvA, AAU) to conduct a series of investigations that identify specific types of experiences with art. We will connect these to changes at individual (neurocognitive, emotional, health) and societal (prosocial and political attitudes) levels. We will capture these experiences in leading museums and urban centers across Europe and in individuals’ home and working contexts. Second, ARTIS will continuously contextualize and challenge the empirical data using theoretical approaches from philosophy (HUB) as well as political science and art criticism (UOXF, RHUL). Third, we will combine this empirical and theoretical focus with a series of interventions, workshops, and experimentations that will be developed in tandem with art schools (UAB, KHB, UOXF), artists, and galleries that focus on generating new thinking, engagement, and action with regard to societal challenges. Fourth, ARTIS will translate the insights gained by our comprehensive methods and co-creations with artists into policy guidelines (FDU) that will be disseminated by key stakeholders in art and culture (IFNU). Throughout the project, we will consider both mainstream as well as marginalized and disengaged individuals. ARTIS will therefore address the need to capture, assess, and harness the societal impact of the arts by providing novel methodological tools, and building bridges among scientists, artists, and policy-makers.

Keywords: transformation,empirical assessment,individual and societal change,bottom up policy creation,practice based art research,co creation
Shape controlled spin-Orbit memories : Fabrication process and Technology transfer (SOFT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: France,France
Call: Call for proposals for ERC Proof of Concept Grant (ERC-2020-PoC, 2020)
Start date: 2021-02-01
End date: 2022-10-31
Duration (months): 21.0
Total project cost (EUR): 162857.14
EU funding (EUR): 120000.0
Participants: 2
Project status: CLOSED

Non-volatility is the main physical feature that fast memories, such as SRAM, are still lacking. Non-volatile memories could increase computing performance while reducing significantly the power consumption. The only viable option for sub-ns nonvolatile memory is the Spin Orbit Torque Magnetic Random Access Memory (SOT-MRAM). The main roadblock towards the integration of the SOT-MRAM is that the reproducible bipolar switching requires the application of a static in plane magnetic field. “Zero-field” SOT switching is still a challenge, which motivates active research on this topic. Within the “SMART Design” ERC-StG project, we are developing an innovative approach for this problem. We discovered that it is possible to determine the switching polarity by the shape of the magnetic free layer. This approach meets all the physical requirements for the SRAM replacement (scalability, switching time, switching current…), but the nano-fabrication of devices with complex shapes using standard u-v lithography tools is difficult and expensive. Here we propose to develop an innovative fabrication technique, adapted for complex shapes, based on ion irradiation. The technology provider is participating to the project, while the potential end-user of this technology is an external collaborator.

Keywords: spin orbit torque,magnetic random access memory,ion irradiation
Next generation Image Processing Engine to support the creation, processing, deployment and transmission of super high definition images for large format ‘smart’ digital displays and signage (SuperHD-ToolBox)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: United Kingdom
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2015, 2015)
Start date: 2015-12-01
End date: 2016-02-29
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The digital marketing industry is poised to rapidly grow in all market segments over the next five years. The three primary market segments: Interactive Displays, Video Walls and Digital Signage; have high projected growth with the lowest compound annual growth rate (CAGR) set at 11.9% for Interactive Displays. This presents a lucrative business opportunity for a Company able to bridge the gap between the underlying technology and what is available on the market. Image Processing Techniques Limted (trading as Omnitek) will seize this opportunity by developing, commercialising and marketing a SuperHD Tool Box that will create, store and transmit SuperHD (8K and above) moving images to large-format display screens for the digital advertising industry. Furthermore, our Tool Box will convert lower resolution images to SuperHD images for these large-format displays, making it backwards compatible with current broadcasts. We have a market ready UltraHD 4K Tool Box that analyses, generates and converts any lower resolution format to 4K, as well as conducting down-conversions if required. The SuperHD Tool Box will be based on the Ultra 4K Tool Box, albeit with the higher processing capacity required for SuperHD images. In our Phase 1 Project, we aim to complete; a Technology Watch exercise, an IP Protection and Exploitation Strategy, Identification and Engagement of Development and Distribution Partners, and a detailed elaboration of our Business Plan. The development of the toolbox and its components, and the implementation and verification of the image processing engine will be carried out in our subsequent Phase 2 Project. The SuperHD Toolbox is expected to be commercially available by March 2017.

Keywords: superhd,video wall,digital marketing,digital signage,interactive displays,smart,processing,transmission,super hi vision
Novel Cell Migration Assay Based on Microtissue Technology and Tissue-Specific Matrices (MATRIXASSAY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Australia,Ireland,Switzerland,United States,United Kingdom,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2015-06-01
End date: 2019-05-31
Duration (months): 48.0
Total project cost (EUR): 1053000.0
EU funding (EUR): 931500.0
Participants: 10
Project status: CLOSED

Cell migration assays are commonly used to study wound healing, cancer cell invasion, and tissue development. Problems associated with the gap closure assays typically employed are that: (i) the stopper or scratch used to make the migration zone damages the extracellular matrix (ECM), (ii) the migration zone size is limited by the size of the stopper, and (iii) the scratched migration zone shapes and sizes are irreproducible. Cell migration is strongly coupled with the structure and mechanical properties of the ECM, and damage to the ECM alters the cell migration path. The main objective of this project is to develop a prototype novel cell migration assay, which will significantly improve the predictive power of cell-based assays while avoiding problems associated with existing assays, based on seeding cells precisely on pristine extracellular matrix tissue mimics with native-like cell-functionality and reproducible migration zones. In accomplishing this, we will also address the following questions: • What are the structure-property relationships between collagen I matrices with controlled thicknesses and fibril diameter and alignment, and their mechanical and electromechanical properties? • What are the critical parameters for achieving functional bonding between the substrate and the highly anisotropic viscoelastic collagen I matrices and controlling the overall mechanical properties? • Does the distribution of collagen fibril polar ordering, i.e., piezoelectric domains, influence cell migration? • What parameters control crimp formation in tendon-like collagen I matrices? • What parameters control and explain the unusual viscoelastic properties (e.g., they not depend on the speed of deformation, at least within the interval 0.01 - 1 mm/sec) of tendon-like collagen matrices? • Which cell types, including cancer cells, co-align with collagen fibril alignment or crimp direction?

Keywords: cell migration assay,microtissue,3d cell based assay,biomechanics,mathematical and numerical modelling,indentation
Dynamics and Thermodynamics of Ultradilute Liquids (UltraLiquid)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-09-01
End date: 2021-08-31
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

Quantum mixtures dominate the physics of helium liquids, neutron stars, nuclear matter, quark-gluon plasma, quantum magnets and superconductors, but these systems are so dense that their complete understanding remains a distant goal. Ultracold quantum mixtures of two bosonic gases constitute an ideally-tunable platform which allows for a complete control over interactions, temperature, and dimensionality, an in-depth understanding of the physics at stake, and the exploration of radically new phenomena. In state-of-the-art experiments on these mixtures, small clusters of atoms (1000-10000) were shown to become self-bound and highly-incompressible, due to the balance of attractive and repulsive forces. First observed in 2017, these liquid droplets constitute a new state of matter, much denser than quantum gases, but orders of magnitude more dilute and colder than any other liquid in Nature. A key property of these systems is that mean-field interactions are tuned to be overall weakly-attractive, so that the stabilization mechanism which leads to droplet formation is provided only by quantum fluctuations. In mixtures where atoms of one component largely outnumber the others, the minority atoms become dressed by majority collective excitations forming Bose polarons, first observed in 2016. When polarons are immersed in a weakly-interacting bath, a controlled theoretical approach is possible even when polaron-bath interactions are strong. Droplets and polarons constitute, respectively, the balanced and the highly-imbalanced limits of quantum mixtures, and the "UltraLiquid" project will lay theoretical firm ground for the unified description of their dynamics and thermodynamics, which will direct future experiments, and in close collaboration with our team. These systems allow for far-reaching investigations of quantum many-body effects and high-resolution measurements inconceivable so far. These promise innovative applications in quantum metrology and quantum sensing.

Keywords: ultracold atomic gases,quantum bose mixtures,bose polaron,liquid droplet,dynamics,thermodynamics,many body,few body
DNA Lattice-Encoded Information for Genotype-to-Phenotype Evolution of Self-Replicating Synthetic Cells (DNA-ENC SYNCELLS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-03-01
End date: 2020-02-29
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

Within the framework of DNA-ENC SYNCELLS I will develop a synthetic inheritable genome capable of Darwinian evolution which encodes for the phenotype of self-replicating synthetic cells. The defining principles of life, namely compartmentalisation, replication and evolution, will thus be realised in a completely synthetic system for the first time. Two types of DNA tiles – a stiff and a soft tile – arranged in a lattice will serve as bits of information, replicating, without any enzymes, via mechanical scission. The DNA lattice will further act as an artificial cytoskeleton specifying the mechanics and shaping the phenotype of synthetic compartments assembled on a microfluidic chip. After sequentially adding the DNA tiles and catalysts for lipogenesis, the synthetic cells will be subjected to multiple growth and mechanically initiated division cycles. Variations in the mechanical properties will influence the division rate and thus lead to evolution in heterogeneous populations. The evolutionary trajectory of the system will be studied under different selection pressures. Within this two-year fellowship, hosted at the Max Planck Institute for Medical Research in Heidelberg and supervised by Prof. Joachim Spatz, I will contribute to the fundamental knowledge of synthetic cells and enhance its applicability using programmable man-made materials. Greatly profiting from the synergy between my expertise on DNA nanotechnology and the host’s high-quality research on microfluidics, synthetic biology and biophysics, this interdisciplinary project will open up broad perspectives for cellular machines capable of autonomous cargo transport, pathogen recognition or as substrates for 3D-bioprinting and tissue repair in vitro and in vivo – the envisioned focus of my subsequent career in research.

Keywords: bottom up synthetic biology,dna nanotechnology,dna origami,dna tiles,protocells,synthetic cells,microfluidics,lipid vesicles,guvs,self replication,genotype to phenotype evolution
Deconstruction as Critical Method in Political Theory (DECON)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-07-15
End date: 2021-07-14
Duration (months): 24.0
Total project cost (EUR): 212194.8
EU funding (EUR): 212194.8
Participants: 1
Project status: CLOSED

Deconstruction as Critical Method in Political Theory ‘Deconstruction as Critical Method in Political Theory’ (DECON) explores the critical potential of deconstruction for three important - but contested - concepts in political theory: democracy, sovereignty and universality, and systematises deconstruction as a methodological and theoretical framework for political theory. This is done through methodological and conceptual development within deconstruction and through critical conversation with other approaches in political theory. The overall objective of DECON is to develop deconstruction as a systematic approach within political theory. The proposed research is highly relevant for current academic and political debates about the challenges to liberal democracy from populism, the representative character of contemporary democratic institutions, and the possibility for social critique in the face of post-truth politics. My wager is that deconstruction can provide a novel and productive perspective on these debates – but, in order to do so, it is necessary to develop deconstruction in a more systematic fashion so that it can enter into critical conversation with other, more mainstream approaches in political theory. I pursue this project in the political theory research group in the Department of Political Science and in the Centre for Anthropological, Political and Social Theory (CAPS) at the University of Copenhagen (UCPH), where I will be part of an international research environment focusing on critique and critical theory in the social sciences. The expected impact of the Marie Skłodowska-Curie Action consists of two journal articles and a book manuscript as well as organisation of workshops and a reading group, seminar and conference presentations, and public dissemination activities. This is in addition to essential training n dissemination for non-academic audiences and in research and administrative leadership.

Keywords: critical theory,critique,deconstruction,democracy,jacques derrida,sovereignty,universality
Exploring selected long non-coding RNAs as diagnostics and therapeutic targets for heart failure (LONGHEART)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-06-01
End date: 2021-05-31
Duration (months): 72.0
Total project cost (EUR): 1816250.0
EU funding (EUR): 1816250.0
Participants: 1
Project status: CLOSED

Despite clinical advances, diseases of the cardiovascular system are the most common cause of morbidity and mortality in the EU with currently 50 million people suffering from heart failure. These important challenges call for a better understanding of underlying mechanisms to enable development of innovative, effective diagnostic and therapeutic strategies for heart failure. Cardiac stress such as myocardial infarction or hypertension leads to cellular “remodeling” of the left ventricle resulting in heart failure. Protein-coding genes originate from only 1.5% of the genome, whereas the larger remaining portion is often transcribed to non-coding RNAs, of which functional importance is still ill understood. We pioneered a role of small microRNAs as diagnostics and therapeutic targets for heart failure (Nature, 2008; Nature Comm, 2012, J Clin Invest, 2014). We now will focus on the larger fraction of long non-coding RNAs (lncRNAs) and their functional roles, as well as diagnostic and therapeutic use in heart failure. The proposal has the following interconnected objectives: a) identify novel functional relevant cardiac remodeling-associated lncRNAs; b) characterise key lncRNA cardiac targetomes; c) investigate lncRNA-paracrine mechanisms and the diagnostic and prognostic potential of cardiac-derived extracellular lncRNAs using large clinical cohorts; and d) discover their therapeutic potential to prevent cardiac remodeling in clinically relevant animal models. Innovative molecular and cell-based methods, a unique lncRNA-shRNA library, genetic animal models and availability of large clinical biobanks will form the basis for a successful strategy. LONGHEART will lead to ground-breaking new insight into the role of lncRNAs in the heart. These findings will firmly establish lncRNA-based mechanisms to identify fundamentally novel diagnostic and therapeutic entry points for a most serious clinical important disorder in dire need for new diagnostic and therapeutic paradigms.

Keywords: non coding rnas,long non coding rnas,heart failure,myocardial infarction
Remote sensing INdicators for DROught monitoring (INDRO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-05-01
End date: 2019-08-20
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Droughts affect most parts of the world. According to the recent previsions of the Intergovernmental Panel on Climate Change1 (IPCC), more frequent and severe droughts are expected. This observation makes it a priority to improve the existing methods of monitoring droughts and their impact on terrestrial ecosystems. Early warning systems need to be developed. Remote sensing (RS) technologies are well-placed to provide such monitoring. Thanks to RS, droughts can be monitored at large scale and at short time resolution (e.g., daily). The proposed project “INDRO” will focus on the definition of new RS-based indicators able to monitor vegetation status and how it is responding to drought. For example, the RS indicators implemented at the moment within the European Drought Observatory (EDO) early monitor system are not sensitive to rapid changes in plant photosynthesis since these indicators have no direct link to plant photosynthetic functioning. The project will analyse the relationships between ecophysiological variables, light use activity (LUE) and existing RS indicators calculated with the data from several satellite sensors. This analysis will reveal which sensors, and which spatial and temporal resolutions are best at quantifying drought. A new generation of RS indicators will be developed to give a better description of plant photosynthetic functioning in drought conditions. The project will map these new indicators for southern Europe to identify the areas affected by drought. Overall, the creation of new RS drought indicators, and the better definition of drought events they bring, will help the development of ecological models and early warning systems, and underpin new avenues for the improvement of national and international drought mitigation and adaptation strategies.

Keywords: drought monitoring ecosystem productivity light use efficency early warming systems