Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Marine Coastal Ecosystems Biodiversity and Services in a Changing World (MaCoBioS)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Fighting and adapting to climate change
Action type: Research and Innovation actions
Countries involved: Germany,Ireland,Spain,Italy,Norway,Sweden,Jamaica,France,France,France,France,Netherlands,United Kingdom,United Kingdom,Portugal,United Kingdom
Call: Inter-relations between climate change, biodiversity and ecosystem services (H2020-LC-CLA-2019-2, 2019)
Start date: 2020-06-01
End date: 2024-05-31
Duration (months): 48.0
Total project cost (EUR): 6980657.5
EU funding (EUR): 6980657.5
Participants: 19
Project status: SIGNED

The EU 2020 Biodiversity strategy and 7th Environment Action Programme highlight the importance of halting the loss of biodiversity and ecosystem services (ES) by preserving ecosystems and fully integrating environmental requirements into policymaking to face climate change (CC). The main challenge to help the EU deliver on these targets is to fill knowledge gaps on inter-relations between CC, biodiversity and ES, and to ensure an effective transfer of knowledge to relevant stakeholders. Marine coastal ecosystems (MCE) are European priority habitats as almost half of its population lives in its maritime regions. MaCoBioS objective is to ensure efficient and integrated management and conservation strategies for European MCE to face CC. To this end, MaCoBioS has assembled a multidisciplinary team of experts to fill the lack of knowledge on the impacts of CC on the most important MCE (seagrass beds, coral reefs, mangroves, coralligenous and calcareous bio-concretion assemblages, salt marshes and kelp forests). Four specific objectives have been developed: 1) Develop new empirical models on the interaction between CC, biodiversity, functions and services in MCE along a geographical gradient from the tropics to the sub-polar regions, incorporating indicators of the ecological condition in the functional modelling of MCE. 2) Establish a framework to assess the vulnerability of marine social-ecological systems under CC scenarios. We will develop vulnerability indices specifically for that purpose. 3) Evaluate the effectiveness of nature-based solutions and protection measures at enhancing the resilience capacity of MCE and the delivery of services, with the end goal of providing long-term solutions to CC threats. 4) Provide evidence-based guidance for marine policy formulation and innovative research pathways to support policymakers in developing cost-effective strategies and create further research opportunities to meet the targets of EU strategies on Biodiversity and CC.

Keywords: ecosystem services,ecosystems ecological condition,nature based solutions,policy guidance
writing the Sleep CRisis: 24/7 cAPitalism and neoliberal Subjectivity (SCRAPS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 257209.92
EU funding (EUR): 257209.92
Participants: 1
Project status: TERMINATED

Sleep is in crisis in the twenty-first-century Global North. People fail to sleep the eight hours recommended by the WHO and sleep disorders are on the rise. A medical humanities intersection of literary/cultural studies with critical theory, philosophy of technology, and STS, SCRAPS is the first study to investigate cultural engagements with this public health issue. I consider twenty-first-century Anglophone fiction, non-fiction (memoirs and self-help manuals), and digital culture (mHealth apps and sleep hygiene blogs) to advance our understanding of the impact of neoliberal ideologies on health. The focus on cultural production serves to interrogate the crisis’s affective dimension. Through theoretically informed close readings, I explore the affects and concerns about contemporary life mobilised by the discourse of a sleep crisis and what these reveal about the relationship between individual health and neoliberal ideologies. My aim is to articulate a new theory of the affects (such as insomnia, exhaustion, burnout, and anxiety) produced by the neoliberal temporal regimes and forms of subjectivity that arguably underlie the sleep crisis. In addition to proposing a timely scholarly intervention, SCRAPS seeks to accelerate my professional development as an interdisciplinary researcher. At META, POLIMI’s innovative network of Social Sciences and Humanities for Science and Technology, I will receive training in new methodologies from philosophy of technology and STS necessary to carry out SCRAPS’s analysis of digital culture. I will also develop my profile through an ambitious programme of dissemination. A monograph, three research articles, a field-defining conference, and an edited special issue of conference proceedings will engage interdisciplinary academic audiences. An art exhibition, articles in the media, and a website will engage the wider public. Two workshops with medical and mental health professionals will create pathways to inform medical practice.

Keywords: contemporary writings,digital culture,self help,fiction,memoirs,affect theory,temporal regimes,theories of time,theories of subjectivity,mhealth,quantified self,digital health
Monasteries as Institutional Powers in Late Antique and Early Islamic Egypt: Evidence from Neglected Coptic Sources (MONASPOWER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-04-01
End date: 2018-03-31
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

Egypt during the Late Antique and Early Islamic periods (broadly the 5th to 8th centuries CE) was a multicultural and multilingual country. Greeks, Egyptians, and, later, Arabs populated the land, speaking Greek, Coptic (the last form of the indigenous Egyptian language), and Arabic. Before the Arabic conquest of 640-642 CE, Christianity was the predominant religion of Egypt, and continued to be so for a while after the conquest, until the 8th and 9th centuries when conversion became more widespread. Centuries of co-existence brought Greeks into contact with Egyptians and vice versa, yet the picture of Late Antique Egypt is a largely Greek one: Greek was the official language of the administration and the majority of Greek non-literary textual finds from this period are also in Greek. As a result, studies on life and especially the economy have focussed on the evidence written in Greek. This study does not seek to study the complex social, cultural, linguistic, and religious interactions at play in the country during this time. Instead, it will provide a new perspective on the economic landscape of Egypt. Monasteries had been a significant part of the Egyptian landscape since the beginnings of Christianity in the country. Life inside these institutions was recorded primarily in Coptic. Despite the importance of monasticism and the body of available Coptic texts, their position within the Egyptian administrative and economic framework has largely been ignored, with attention placed instead on the contemporary large Greek estates. The aim of this project is to study the economic position of Coptic monasteries during this timeframe on the basis of the neglected evidence from two sources: the monastery of Apa Thomas at Wadi Sarga and the corpus of non-literary Coptic texts in the collection of the University of Copenhagen.

Keywords: egypt,coptic,ancient economy,papyrology,monasteries,late antiquity
Novel vaccine and diagnostic strategies against Schmallenberg virus (SchmaVirusVacDiag)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-15
End date: 2017-06-14
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

Schmallenberg virus (SV) is a pathogen that has been discovered in European livestock 3 years ago. Since then, it has been found that this virus is associated with disease in sheep, goats and cattle across Europe . In livestock, the symptoms associated with the disease include stillbirths and malformations in newborn animals. The presence of the virus in Spain, France, Germany, Italy, the UK, the Netherlands as well as Russia, has shown that this disease is a fast spreading threat to the European livestock industry, and has the potential to cause significant economic impact across the continent. Furthermore, due to high volumes in international trade of livestock, the potential of this disease to spread beyond Europe poses another potential threat to the industry. Recent work using a related bunyavirus (Rift Valley Fever virus) has found that effective DNA vaccines can be generated . These vaccines have the advantage of being administered easily, having low-manufacturing costs, and providing long-lasting efficacy-making it ideal for large-scale vaccination campaigns. Furthermore, studies on related viruses have shown that monoclonal antibodies can be generated for use in diagnostic testing. Using these concepts, we propose to extend this principle to Schmallenberg virus, in order to: i) develop an easy-to-use diagnostic test for Schmallenberg detection; and ii) develop a DNA vaccination strategy that could be used to limit further future outbreaks.

Keywords: schmallenberg virus,livestock,dna vaccine,structural biology,diagnostic testing,bunayvirus,glycoprotein,nucleoprotein,rna virus,recombinant proteins
MOS-based Quantum Information TechnOlogy (MOS-QUITO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Italy,Switzerland,Finland,France,Denmark,United Kingdom,United Kingdom
Call: Generic micro- and nano-electronic technologies (H2020-ICT-2015, 2015)
Start date: 2016-04-01
End date: 2019-09-30
Duration (months): 42.0
Total project cost (EUR): 3973360.75
EU funding (EUR): 3450622.0
Participants: 7
Project status: CLOSED

Quantum computing is now widely regarded by many in academia, governments and industry to represent a major new frontier in information technology with the potential for a disruptive impact. Many different materials and approaches have been explored, with a narrowing of focus in recent years on scalable implementations based on solid state platforms. In particular, there is now strong evidence that silicon, the primary platform technology for today’s processor technology, inherently possesses many key properties that make it advantageous for quantum computing. Two types of qubit based on spins in silicon nano-devices made in academic research labs have already been reported with demonstrated high-fidelity operation. Our project builds on this success and aims to take this technology to the next readiness level by showing that silicon-based qubits can be realised within a full CMOS platform, using the 300mm-scale fabrication facilities in our consortium. In doing so we will demonstrate the true potential of silicon based qubits in terms of scalability and manufacturability. Our focus is on distilling the silicon device design down to the simplest core element necessary to demonstrate qubit behaviour, in order to lay the foundation for a scalable technology. We will design, model and fabricate these qubit devices, and then benchmark them using key operating parameters. Our attention is not limited at the lowest level technology layer where the qubits reside, and includes higher control layers necessary to operate such devices, including demonstrating strategies for achieving local control and readout in large-scale arrays without cross-talk and developing cryo-CMOS electronics to support the qubit operation. Both of these may be spun-out and yield their own technological impacts. Thus, our holistic approach offers a wider opportunity to harness the tremendous proven capabilities of integrated CMOS technology to become a key driver of quantum technology development.

Keywords: quantum information,spin,nanoelectronics
Poverty in the Qur’ān: Medieval Islamic Interpretations and Uses (PiQ)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-03-01
End date: 2023-02-28
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

What does the Qur’ān say about poverty? Is poverty caused by divine will and thus inevitable? Is it a punishment, a trial, or a sign of divine favour? Who are the poor, what is their position in the society, and how should they be treated? What is the relation between poverty and moral virtue? These questions occupied medieval Muslim thinkers and re-emerged in contemporary discussions among scholars, Muslim intellectuals, and the wider public on Islamic economic ethics, poverty alleviation, social justice, and development in Muslim societies. Yet, historical research on poverty in the Qur’ān is scarce. This project approaches the question of poverty in the Qur’ān from the reception history perspective. In contrast to previous research which focused on the Qur’ānic ‘view’ on poverty, it explores the dynamic tradition of reading poverty in the Qur’ān in medieval Muslim societies, covering the period from the 8th to the 13th centuries CE. Based on a large corpus of medieval Arabo-Islamic sources, both editions and manuscripts, it aims to reconstruct the history of interpretation of Qur’ānic verses on poverty and to examine their use in poverty-related discourses (e.g. theological, ethical, juridical) and practices (e.g. rituals of protection from poverty, disputations). Offering the first systematic study on this subject, the project will make a contribution to the study of medieval Islamic ideas and attitudes to poverty and poverty-related practices, and shed light on the role of the Qur’ān in shaping them. The project will result in the publication of two articles in peer-reviewed journals, an initial draft of a monograph on poverty and the Qur’ān, and a catalogue of the Qur’ānic verses used in poverty-related contexts which will be made fully accessible to specialist and non-specialist audiences through open access digital resources.

Keywords: qur an,reception of the qur an,qur anic exegesis tafsir,qur anic studies,islamic studies,poverty,in medieval muslim societies,history of religion
Psychological, social and financial barriers to energy efficiency (PENNY)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Switzerland,Hungary,Netherlands
Call: Socio-economic research on consumer's behaviour related to energy efficiency (H2020-EE-2016-RIA-IA, 2016)
Start date: 2016-09-01
End date: 2019-08-31
Duration (months): 36.0
Total project cost (EUR): 1985237.5
EU funding (EUR): 1501837.5
Participants: 6
Project status: CLOSED

The project aims at improving our understanding on behavioural mechanisms in energy efficiency, following an interdisciplinary and broad behavioural science approach. The project will provide an empirical and numerical assessment of the psychological, social, economic and financial factors that influence energy efficiency in the residential and industry sectors By paring with energy utilities and retailers in different European countries, the project will conduct scientific experiments (A/B testing) which will enhance the design of policies aiming at maximizing energy efficient behaviors. The project will use novel data from different European countries to take into consideration institutional and political factors. The project will analyze consumers’ behavior related to the consumption of energy, the investment in energy efficient products, as well as the renovation of buildings. Finally, ex ante assessment will be executed using improved energy economy models, which will generate quantitative information with regard to expected impacts of EU and global policies.

Keywords: behavioural sciences,b testing,impact assessment
CORolla® - a disruptive "spring like" metallic device for permanent treatment of diastolic heart failure. (CORolla)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-11-01
End date: 2019-02-28
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Heart Failure with preserved ejection fraction (HFpEF) is a life-threatening form of congestive heart failure condition annually affecting more than 25 million people globally. HFpEF occurs commonly in older individuals and has higher prevalence in women. As the European population is aging (over 65 accounting for 19.2% of the total European population, 2.4% more than 10 years ago), HFpEF will affect more and more people, representing significant economic and social challenge for the patients, their families and National Health Systems. Currently there is no solution on the market for such heart failure condition. Though the effect of some drugs used in the treatment of HF with reduced ejection fraction are currently studied for HFpEF in large clinical trials (e.g. PARAGON-HF Trial, TOPCAT Study), a new approach based on the left interatrial shunting is needed. The CorAssist introduces a “spring-like” metallic device, CORolla® for augmentation of diastolic function of the heart. The CORolla® is implanted inside the left ventricular of the heart in a minimally invasive procedure. The self-expanding, internal device harnesses the elastic energy during systole (contraction) state and releases it during diastole (relaxation) in order to augment dynamics of left ventricular relaxation and filling. CORolla® manages to impact directly and improve the impaired diastolic function, needing only one-time procedure. CorAssist Cardiovascular has the vision to become the first company in the world to treat HFpEF. The EC grant is instrumental to this ambitious goal and company’s growth trajectory. Following a very promising validation in animals and humans, the company is planning to start first sales of CORolla® by the end of 2021.The SME Instrument project perfectly aligns with this objective, as it would provide the company with the financial resources necessary to complete the clinical study within the planned time-frame.

Keywords: heart failure,diastolic,hospitalizations,treatment
An innovative drug development and repurposing platform for rapid identification and validation of antimicrobial therapeutics (Signia)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2020-06-01
End date: 2023-05-31
Duration (months): 36.0
Total project cost (EUR): 3403263.5
EU funding (EUR): 2382284.45
Participants: 1
Project status: SIGNED

Pharma industry is facing the challenge of high-cost and time-consuming processes for de novo drug development (€1-2 billion and 10-17 years per marketed drug), also influenced by high failure rates (only 10% of drug candidates are approved for market entry). As a result, an increasing number of firms seek alliances based on repurposing existing drugs for new indications to deliver the needed productivity increases, shifting the focus of R&D to smaller biotech companies. Among all infectious diseases, acute respiratory tract infections are the main source of acute diseases worldwide with over 17.5B deaths per year, notably killing newborns and young children. They are caused by over 200 viruses and handful virus-bacteria coinfections; however, today we only have vaccines and few treatments for Influenza and respiratory syncytial virus. Signia is a French start-up offering a disruptive solution to combat these emerging infections globally; a drug development platform for next-generation antimicrobial treatments, by repurposing ready-marketed drugs and repositioning unsuccessful pharma pipelines candidates. Signia strategy involves a complete paradigm shift, based on targeting the global response of the host cell instead of a specific molecular determinant of the pathogen. Our innovation will not only give rise to better treatments against respiratory infections and significant shortening of response time to widespread outbreaks, but also will enable both a rapid transition of drugs from the pipeline to the market and a rapid return of investment for pharmas. Phase 2 will let us reach the full capability of our platform and the clinical validation of the optimized nebulized Diltiazem, our drug candidates at the most advanced stage of validation as repurposed host-targeted inhibitor of influenza infection. We forecast €31M revenues (with a ROI of 9.72 with a corresponding EBITDA of 70.51% after 5 years in the market) and increase our company´s workforce to 14.

Keywords: outsourced antimicrobials development,bioinformatic modelling infections,respiratory epithelial cell models,collaborative drug development ecosystems
New Cost Efficient Business Models for Flexible Smart Grids (NOBEL GRID)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: A single, smart European electricity grid
Action type: Innovation actions
Countries involved: Spain,Italy,Italy,Austria,Germany,Germany,Spain,Spain,Belgium,Greece,Romania,Belgium,Sweden,Greece,Netherlands,United Kingdom,Portugal,United Kingdom
Call: Distribution grid and retail market (H2020-LCE-2014-3, 2014)
Start date: 2015-01-01
End date: 2018-06-30
Duration (months): 42.0
Total project cost (EUR): 13864309.48
EU funding (EUR): 11725973.15
Participants: 28
Project status: CLOSED

NOBEL GRID will develop, deploy and evaluate advanced tools and ICT services for energy DSOs cooperatives and medium-size retailers, enabling active consumers involvement –i.e. new demand response schemas – and flexibility of the market – i.e. new business models for aggregators and ESCOs. Through the dual-use of telecommunication networks, and validating the integration of renewable generation presence and demand response systems, NOBEL GRID will offer advanced services to all actors in the retail markets of the electricity system in order to ensure that all consumers will benefit from cheaper prices, more secure and stable grids and low carbon electricity supply. The project results will be demonstrated and validated in real world environments with active involvement of all the actors, and based on the new business models defined during the project.

Keywords: demand response,standards,legislation,business models,storage