Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Utilizing Pig By-products as Heat Source to Save Recycling and Energy Cost. (PigHeat)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-11-01
End date: 2018-08-31
Duration (months): 22.0
Total project cost (EUR): 1984566.25
EU funding (EUR): 1389196.38
Participants: 1
Project status: CLOSED

BIGAS ALSINA, a family owned company specialized on machinery manufacturing for the Food sector, aims to commercialize PigHeat, a novel technology that allows processing pig fur and pig roughing. Right now, pig fur and roughing are simply dried in order to reduce weight and volume, and used as fertilizer in landfills. In other words, pig meat processing means that there is a waste that actually needs to be disposed of, which is the least desirable effect of waste. Not only does pig meat processing incur waste disposal, it also implies an important investment in energy to remove water as well as removal cost. This cost is directly paid by the slaughterhouse. Through the proposed PigHeat processes, pig fur and roughing can be used as an alternative source of fuel that creates steam and service water instead of using gas, diesel or electricity. The meat processing industry consumes high amounts of energy. By using pig fur and roughing as fuel, an environmental waste problem is transformed into an important way to save 15% of heating energy, while promoting waste valorization and a circular economy within the sector. This is achieved in 4-steps: i) homogenization, ii) hydrolysis, iii) drying and iv) combustion. The obtained product is a Co2 neutral biomass with exceptionally high heating value (even higher than wood pellets) that can be used in the daily operations of the same installation. Due to the stringent waste regulations, the 1,700 medium sized slaughterhouses in Europe are looking for a solution. Not only that, they are operating on very low margins and PigHeat will allow them to cut energy expenses, thereby increasing profits. Buying PigHeat implies certain costs for slaughterhouses, however the savings will fully have paid for the machinery in less than two years. Offering attractive payment modules, our innovative solution is likely to conquer the market swiftly.

Keywords: pig hair,pig fur,roughing,valorisation,circular economy,biomass,environment,environmentalfriendly,co2 neutral,process efficiency,meat sector,renewable energy,animal,byproduct
Multidimensional Analysis of Axis Patterning in Plant Embryo (MAAP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-08-01
End date: 2019-07-31
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

Plant cells are immobile, therefore positional signaling is essential for body patterning. While many genes involved in positional signaling in plants are known, we currently lack a mechanistic understanding of their functions. Embryonic axis pattering is the earliest and simplest instances of positional signaling. In Arabidopsis thaliana, embryo is initially radial symmetry. Soon after, the embryo switches to bilateral symmetry and development continues along the newly-established axis. How these patterns emerge from a small group of homogeneous cells remains a fundamental unanswered question in developmental biology. Answering this question requires an in-depth analysis of the spatio-temporal relationship between gene expression and cellular patterns. Today, advanced microscopy and latest image analysis allow us to quantify division, growth and gene expression in individual cells throughout embryogenesis. The host group has been studying the regulatory role of homeobox proteins, PHABULOSA (PHB) and PHAVOLUTA (PHV). Distribution of PHB/PHV protein is restricted by microRNA to apical embryo, triggering embryonic shoot formation. If the PHB/PHV distribution is a positional signal reflecting apical-basal axis, how do they regulate cellular growth and division patterns to establish axis? I will generate a 4D map of axis patterning, extract high quality quantitative data to develop spatial computer models, and examine the interplay between geometry and genetic regulation on axis patterning. I will also apply same approaches to study embryos in other Brassicaceae species. Such comparative developmental analysis will reveal the core mechanism of axis formation shared among these species and also provide insights into the origins of their embryonic morphological diversity.

Keywords: plant embryology,embryonic axis formation,comparative development,quantitative image analysis
The Role of extreme drought and legacy EFfects of long-term manipulatiOn of water availability on growth and REproduction of ScoTs pine REFOREST (REFOREST)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-11-01
End date: 2019-10-31
Duration (months): 24.0
Total project cost (EUR): 187419.6
EU funding (EUR): 187419.6
Participants: 1
Project status: CLOSED

Drought has been identified as an important driving factor for forest decline, hence the long-term tree-level growth assessment in relation to drought events is necessary to understanding resistance and resilience of forests. In addition, the seedling physiological responses (photosynthesis and respiration) to varying growing conditions are key to forecast the future composition of temperate forests in Europe. Younger stages of a tree’s life cycle are more sensitive to climate variations than the adult stage. Recent studies demonstrate the important role of transgenerational epigenetic effects for the adaptive capacity of a tree. Although the epigenetic control of gene expression during drought has been shown in trees at the molecular level, little is known at the physiological level. In this context, the overall objectives of this study are to quantify radial growth of Scots pine and oak along a latitudinal gradient from southern France to northern Germany with particular focus on the effects of extreme events, and to quantify the potential role of epigenetic effects on seed germination, seedling establishment and survival in variable growing conditions (temperature, light and water). The objective-1 will be based on annually resolved tree-ring data covering the entire gradient. The distinct role of epigenetic changes on seedling growth and survival (objective-2) will be accomplished applying transplanting experiments with seed from long-term irrigated trees (13 years) and trees growing under natural dry conditions, in the field and in the laboratories of WSL, Switzerland. The project will explore the adaptive strategies used by Scots pine trees to drought events, which will strengthen our understanding on the complex relations among climate and ecophysiological mechanisms, essentially benefiting the development of sustainable forest management strategies under climate change in Europe.

Keywords: extreme drought,dendroecology,stable isotopes,regeneration,climate change,scots pine
An innovative high capacity Accordion bioreactor technology for high performance and low cost microalgae production (Accordion Bioreactor)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Cross-cutting marine and maritime research
Action type: SME instrument
Countries involved: Norway
Call: Supporting SMEs efforts for the development - deployment and market replication of innovative solutions for blue growth (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-01-01
End date: 2017-04-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Access to vital raw ingredients for food/feed production is an increasing challenge in several industries. Biopharmia is a Norwegian company focusing on cultivation of microalgae through its development of a proprietary bioreactor. Through years of expertise and collaborations with experts in the field of microalgae growth, Biopharmia have developed and patented the Accordion bioreactor, a proven and efficient platform for industrial scale production of high quality microalgae, at lower energy and decreased production cost, compared to other solutions. This technology aims to strengthen Europe’s position in the microalgae market, which is currently weak due to cheaper, low quality foreign competitors. The technology describes the unique wave configuration comprising the frame work of the bioreactor, which contributes to higher productivity and lower cost of production and investment when compared to competing technologies. The modular design of this closed system greatly minimises the risk of contamination and can be easily adapted to large scale production. Biopharmia need to undertake the proposed innovation project to develop and further test the Accordion technology with multiple algae strains. The company has a close collaboration with the University of Arizona (UA) and has demonstrated the efficiency and productivity of its bioreactors through extensive testing at UA. Biopharmia has supplied biomass to a number of entities in Norway with very good results. Biopharmia has Letters of Intent about supply of biomass to two Norwegian customers in different segments, food supplements and aquaculture. In 2012 the company raised €1 million in private venture capital from IFE Venture. Biopharmia intends to establish initial production using the Accordion technology for the clients the company have an LOI with before expanding production.

Keywords: microalgae,bioreactor,ecoinnovation,blue growth,green tech
Artistic Research in Museums and Communities in the process of Repatriation from Europe (REPATRIATES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Austria,United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-05-01
End date: 2026-04-30
Duration (months): 60.0
Total project cost (EUR): 1993066.0
EU funding (EUR): 1814316.68
Participants: 2
Project status: SIGNED

What innovations to the repatriation of cultural property can be performed by making new originals? The specific objectives of REPATRIATES are to bring together internationally art-based research actions that respond to repatriation, to learn from exchanges between French, German, Austrian and British institutions and stakeholder indigenous communities. REPATRIATES examines how contested objects - whose ownership may remain unclear - can be concieved and exhibited sensitively. It develops strategies for making artistic responses to this material, to propose ways forward for the decolonization of cultural property. This research aspires to shape a pan-European response to the complex political, historical, and affective dimensions of the repatriation of cultural assets. A casuistic approach is taken to analysing four major European museums’ - the Musée du quai Branly Paris, Humboldt Forum Berlin, Manchester Museum, and Weltmuseum Vienna - approaches to concrete, current repatriation processes. Can different modes of property be learnt from cultures whose emphasis is on reciprocal relationships rather than individual material accumulations? Comparing repatriation processes to Mexico, Australia, Nigeria, Bénin and Namibia, REPATRIATES proposes new models of co-ownership. This is essential to redress historical power imbalances and their display as national heritage. What questions can be asked of repatriated objects, as in what personalities, powers, and performances do they bring with them? REPATRIATES’ over-arching objective is to exemplify artistic and stakeholder community dimensions heretofore underrepresented in repatriation debates. Multiple voices gathered in artistic research and fieldwork, from milieus of museum professionals that may be sceptical of repatriation, and those working in politics, social justice, and academics, together produce REPATRIATES that define the significance and future potential of repatriation.

Keywords: decolonization,material culture,intangible heritage,colonial history,museum repatriation,artistic research,anthropology,indigenous studies
The European Agroecology Living Lab and Research Infrastructure Network: Preparation phase (ALL-Ready)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Coordination and support actions
Countries involved: Spain,Germany,Spain,Germany,Belgium,Switzerland,Serbia,Belgium,Hungary,France,Netherlands,Denmark,United Kingdom,Canada
Call: Strengthening the European agro-ecological research and innovation ecosystem (H2020-FNR-2020-1, 2020)
Start date: 2020-11-01
End date: 2023-10-31
Duration (months): 36.0
Total project cost (EUR): 2154175.0
EU funding (EUR): 2136174.0
Participants: 16
Project status: SIGNED

Today, agricultural systems are facing multiple challenges, including climate change, loss of biodiversity, dwindling resources, degradation of soil and water quality. Agroecology can strengthen the sustainability and resilience of farming systems and thus contribute to addressing these challenges. Based on the premise that Open Innovation Arrangements (OIAs) and in particular Living Labs (LL) and Research Infrastructures (RIs) are instruments that have large potential to contribute to amplifying agroecology in Europe, the main aim of ALL-Ready (this project) is to prepare a framework for a future European network of LLs and RIs (to be called “AgroEcoLLNet”) that will enable the transition towards agroecology throughout Europe. It will rely on a highly participatory and inclusive approach and on experimentation in real life situations and thus itself uses a living lab approach. An underpinning principle of the project is strong stakeholder engagement, which has begun in the preparation of this proposal. The project has 3 phases: an initial preparatory phase in which the vision, scope and mission for the Network are defined and the criteria for inclusion in the Network of LLs and RIs as well as other forms of OIAs are defined. This will enable the mapping of current and emerging LLs, RIs and OIAs across Europe and their characteristics, highlighting best cases. In a second phase, different prerequisites/ activites for the future Network will be prepared ‘(sustainability, including funding, governance, capacity building, data and knowledge management). Plans for each of these will be constructed with stakeholders and then tested in a small-scale pilot network and then refined to match needs. Finally, the outcomes of the work will be communicated widely throughout Europe by a variety of mechanisms. One of the final outcomes of the project will be a pilot-tested Implementation Plan for implementing the validated framework of AgroEcoLLNet, within Horizon Europe.

Keywords: agrobiodiversity,organic farming,agroforestry,open innovation,living labs,research infrastructures,soil functions,capacity building,european network,european partnership,pilot activities
Tissue repair functions of MAIT cells: integrating thymic pre-commitment and peripheral signals (MAIT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Immunity, Infection and Immunotherapy
Panel description: The immune system, related disorders and their mechanisms, biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases, innovative immunological tools and approaches, including therapies
Countries involved: France
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2020-10-01
End date: 2025-09-30
Duration (months): 60.0
Total project cost (EUR): 2499500.0
EU funding (EUR): 2499500.0
Participants: 1
Project status: SIGNED

Mucosal associated invariant T cells (MAITs) represent an abundant subset in humans with unique specificity for microbial metabolites. MAIT conservation along evolution indicates important, non-redundant functions. Despite changes in MAIT frequency and phenotype in several infectious and non-infectious diseases, their functions are still unclear. By contrast with mainstream CD4+ or CD8+ T cells, MAITs differentiate into effector cells during thymic development. How the differentiation program imparted in the thymus is modified by tissue and environmental cues to determine MAIT functions in tissues is not known. Our preliminary data support a new function for MAITs in boosting tissue repair in skin wound healing and flu infection. Thus, MAITs would either repair tissues or inflict tissue damage when fighting microbes according to the stage of the disease. To understand how and when the different MAIT functions are turned on and off in vivo we will study: 1) How is the thymic MAIT differentiation program modulated by tissue and environmental cues to determine the location and effector functions of MAITs in skin and lung at steady state? To this end we will develop new genetic methods to modify MAIT development or functions. 2) What are the effector functions of MAITs leading to protection during skin wound healing and flu infection? We will determine the cell types MAITs affect and identify the mediators secreted by MAIT cells. 3) What triggers MAIT protective effect? We will identify the drivers of MAIT activation and assess the requirement for cognate or non-cognate (cytokines) interactions. Wound healing of human skin explants will test the therapeutic potential of modulating MAIT activation. Our results will provide unique insight on the functions of MAIT cells with important implications for therapy of diseases in which MAIT triggering (or inhibition) could be beneficial (or deleterious) such as wounds or infections that damage tissues and thus require repair.

Keywords: innate like t cells
Re(search) (reSEARCH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Ireland
Call: European Researchers' Night (H2020-MSCA-NIGHT-2016, 2016)
Start date: 2016-06-01
End date: 2017-11-30
Duration (months): 18.0
Total project cost (EUR): 159900.0
EU funding (EUR): 159900.0
Participants: 1
Project status: CLOSED

Re(search) will connect the citizens of Dublin with research through two fringe-festival events held in 2016 and in 2017. For each event, Dubliners will be invited to the iconic Front Square of Trinity College Dublin where they will explore how research is addressing societal challenges (the same societal challenges laid out in H2020). The societal challenges will be explored using a range of formats including comedy, drama, dining, story-telling, and citizen-science. These have been chosen to spark conversations between researchers and citizens on issues that matter to people’s lives. Conversations will allow citizens to construct their own views on research topics and the role of research in our society (and as a career). Constructivist approaches to learning are known to lead to enhanced learning outcomes in formal learning settings. This proposal is based on the idea that a constructivist approach to learning can also be applied to informal learning environments, such as Re(search) Night. Dubliners will be made aware of the two Re(search) events through an advertising campaign on Dublin’s Metro train (based on an award winning model designed by the coordinator). Evaluation of the project will be integral to its success with best-practices applied at all stages. Re(search) 2016 and 2017 will be delivered by a management team that has considerable experience in science communication, science education, public engagement and project management. The Re(search) concept outlined in this proposal is a novel way to engage large numbers of citizens. It is based on a number of previous, successful, campaigns and has a strong grounding in published best-practice.

Keywords: societal challenges,citizen science,constructivist approach to communication,multi disciplinary,learning through conversation,research as part of our cultural identity
MEDICINE. Indigenous concepts of health and healing in Andean populations: understanding the relevance of traditional MEDICINE in a changing world. (MEDICINE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Ecuador,United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-11-01
End date: 2019-10-31
Duration (months): 36.0
Total project cost (EUR): 217708.2
EU funding (EUR): 217708.2
Participants: 2
Project status: CLOSED

In the context of a complex global agenda in traditional and complementary medicine, indigenous concepts of health and healing are less well documented and understood. MEDICINE will examine concepts of health and healing from an indigenous and culturally specific context, taking a unique time-depth perspective and with a framework of interdisciplinary methods which integrates archaeological-historical, ethnographic and modern health sciences approaches. MEDICINE offers a novel perspective and methods in the development policies sensitive to indigenous and minority people’s social, economic and health needs and, too, on developing culturally sensitive approaches to the conservation of their ‘intangible cultural heritage’. MEDICINE will also develop novel methodological and theoretical approaches to model how peoples survive and adapt their traditional belief systems in a context of alien cultural impacts. The study population are indigenous Quichua peoples in the northern Andean region of Ecuador, a country where the ER has considerable experience. Models of their understanding of health, illness and healing, and the way these have adapted and changed through time will be used to develop a ‘tool’ transferable to contemporary global policy scenarios. MEDICINE will benefit from the ER's unique perspectives from Medicine and Archaeology to explore the impact of traumatic cultural transition on people, the significance of traditional practices as intangible cultural heritage, and the degree to which the longer-term archaeological perspective can help promote understanding in a vital area of contemporary concern. It will enable her to develop further policy relevant skills, a particular output being contributions to policy and practice in the development of culturally sensitive approaches to the health and social needs of migrant and minority peoples from traditional cultural backgrounds.

Keywords: traditional knowledge,traditional medicine,traditional healing,traditional healers,shamanism,indigenous culture,indigenous policy,intercultural health care,culture change,cultural trauma