Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Social cohesion and subjective well-being: An exploration of their dynamic interplay amongst migrants in Vienna and Budapest (WELLCOH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2027-08-31
Duration (months): 48.0
Total project cost (EUR): 199440.96
EU funding (EUR): 199440.96
Participants: 1
Project status: SIGNED

WELLCOH seeks to explore the relationship between social cohesion (SC) and subjective well-being (SWB) in the case of immigrants in Vienna and Budapest. Its innovative approach is not simply the strong linkage of the two concepts, but rather the attempt to understand their two-way causal relationship within one research framework. The aim of the project is to answer the following questions. How do immigrant communities perceive social cohesion (social exclusion, perceived tensions, intergroup trust etc.) and subjective well-being (life satisfaction, happiness, eudaimonia) in comparison with the native-born population and the European statistics? Has immigrants' well-being improved linearly with their material gains, or has it failed to reach the expected level due to the immaterial factors? What role do social relationships play in this process and how does SWB influence their migration intentions (stay permanently, return to the country of origin, or leave for another country)? How do the group-specific SWB differences influence the strength of social cohesion in Vienna and Budapest, and what are the main differences between the two cities regarding the social cohesion-subjective well-being nexus? The project applies a mixed methods approach, including secondary analyses (literature review, statistical data, international and national surveys: EQLS, EU-SILC, VQLS and the Hungarian microcensus) and the combination of qualitative and quantitative methods: focus groups, interviews and two additional surveys in Vienna and Budapest. The empirical findings will contribute to improving the existing theoretical literature, and they are expected to facilitate more effective, evidence-based policies in both countries. The Challenge of Urban Futures Research Platform at the University of Vienna will host the project under the supervision of Prof. Yuri Kazepov, an internationally renowned expert in urban sociology.

Keywords: migration social cohesion well being integration austria hungary
TOWARDS LARGE-SCALE ADAPTION AND TAILORED IMPLEMENTATION OF EVIDENCE-BASED PRIMARY CANCER PREVENTION PROGRAMMES IN EUROPE AND BEYOND (PIECES)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Cancer
Destination: Cancer
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Australia,United Kingdom,Netherlands,Albania,Italy,Ukraine,Belgium,Norway
Call: Improving and upscaling primary prevention of cancer through implementation research (HORIZON-MISS-2022-CANCER-01, 2022)
Start date: 2023-06-01
End date: 2027-05-31
Duration (months): 48.0
Total project cost (EUR): 6930111.25
EU funding (EUR): 6930111.25
Participants: 16
Project status: SIGNED

The high and growing global burden of cancer urges the need for effective implementation of primary cancer prevention (PCP) programmes targeting modifiable risk factors. However, evidence-based programmes with proven effectiveness under controlled environments often fail when implemented in the real world due to ineffective adaptation and implementation strategies addressing context-specific barriers, leading to programme failures and public health inequities. The PIECES project will develop, assess, and disseminate a cancer-specific methodological implementation framework, the integrated PCP Implementation Toolkit (PCP-IT). PCP-IT will provide an evidence-informed systematic process for (1) identification, selection, and tailoring of PCP programmes, and (2) developing evidence-informed implementation strategies tailored to local barriers and constraints. The PCP-IT will include a comprehensive repository of PCP programmes, their Theories of Change, and materials for systematically adapting the programmes to local needs and cultural constraints. The project involves 16 consortium members and implementation sites from 10 countries of diverse socio-cultural backgrounds and access to up to 77.7 million inhabitants. PIECES provides an ideal naturalistic laboratory to improve and study the up-scaling and implementation of a wide range of primary PCP programmes targeting major risk factors: tobacco, alcohol, low physical activity, HPV infection, sun exposure, and diet. A multi-site case comparison study will be conducted to assess and optimise implementation outcomes. An in-depth realist evaluation using various sociological theories will be conducted to explain the processes by which the outcomes are achieved. The consortium will employ a high-level external Advisory Board with renowned experts, facilitate continuous engagement with stakeholders, and align with the EU and relevant scientific societies to ensure the future continuity of both the repository and PCP-IT. This action is part of the Cancer Mission cluster of projects on ‘Prevention and early detection’.

Keywords: cancer prevention implementation science smoking secondhand smoke alcohol physical activity diet sun exposure hpv infection
Cold War Europe Beyond Borders. A Transnational History of Cross-Border Practices in the Alps-Adriatic area from World War II to the present. (OPEN BORDERS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Slovenia
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2474330.0
EU funding (EUR): 2474330.0
Participants: 1
Project status: SIGNED

This project aims to rethink the history of Cold War Europe by examining the development of transnational cross-border cooperation from the end of World War II to the present. Overcoming traditional narratives of a clear-cut European separation symbolised by the Berlin Wall, a decentralised analysis of recent European history will show us that the question of a divided continent should be reframed. The final objective is to challenge a dichotomous vision of two separate Europes, “East” and “West”, from a new, border perspective. To this end, a highly qualified team of senior and junior scholars under my guidance will focus on the Alps-Adriatic region, a historical area that is now shared by Austria, Italy, Slovenia and Croatia. This case involves a relatively narrow geographical area but an unusually broad typological range of subjects. During the Cold War it was divided among socialist but non-aligned Yugoslavia, capitalist but neutral Austria, and NATO and EEC member Italy. Its development from the "southern end" of the Iron Curtain in 1946 to the "most open border" during the Cold War and a precursor to present-day Schengen Europe, represents a paradigmatic case to study an alternative attitude towards borders, frontiers and boundaries. Drawing on Cold War and borderland studies, social history and the history of European integration, which up till now have not found common ground, our innovative conceptual elaboration will demonstrate the interplay between top-down politics and bottom-up initiatives, thus offering a new, and more nuanced history of Cold War Europe from the border perspective. Reconsidering the European past from this transnational angle, both in terms of geographic and methodological perspectives, will allow us to rediscover the human face of European integration and will offer us a new platform for contemporary discussions on sovereignty, territoriality and belonging and on the future role of borders in Europe and in the world.
SAFETY OF ANTIMALARIALS IN THE FIRST TRIMESTER: AN ADAPTIVE PLATFORM TRIAL (SAFIRE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Global Health EDCTP3
Action type: Research and Innovation actions
Partnership: EDCTP3 (JU-JTI)
Countries involved: Burkina Faso,Congo, The Democratic Republic of the,Kenya,Uganda,Switzerland,United Kingdom,Netherlands,Mali
Call: Implementation research/real life assessment of existing interventions in women and children’s health (HORIZON-JU-GH-EDCTP3-2023-01, 2023)
Start date: 2024-06-01
End date: 2028-11-30
Duration (months): 54.0
Total project cost (EUR): 5191431.44
EU funding (EUR): 5191431.44
Participants: 9
Project status: SIGNED

Background: Malaria in pregnancy can have devastating consequences, particularly in early pregnancy. Effective treatment in the first trimester can significantly improve maternal and pregnancy outcomes. However, first-trimester pregnancies are generally excluded from clinical trials resulting in new and effective antimalarials being withheld from use in early pregnancy. WHO updated its guidelines in 2022 from quinine to artemether-lumefantrine (AL) as the first-line treatment for uncomplicated malaria in the first trimester. However, there are insufficient data on the benefit-harm of other widely used artemisinin-based combination therapies. Objectives: 1) To generate robust evidence on the safety, tolerability, and efficacy of antimalarials for the treatment of uncomplicated P. falciparum malaria in the first trimester. 2) Translate research findings into treatment guidelines and clinical practice. Study design: a) Phase IIIb, non-inferiority, Bayesian adaptive randomised platform trial comparing pyronaridine-artesunate (PA) and AL in Burkina Faso, Kenya and Mali. Primary outcome: Safety. Secondary outcomes: efficacy and tolerability. b) Formative research to inform innovative trial recruitment and retention strategies, c) Acceptability and feasibility to assess values and preferences of antimalarials during early pregnancy, d) implementation research to explore factors affecting implementation of AL in the first trimester to inform translation strategies, and e) cost-effectiveness of PA vs AL. Impact: The trial will provide critical information on the safety and efficacy of alternatives to AL for treatment in the first trimester, benefiting settings where AL is not used and aligning with WHO's strategy of multiple first-line therapies against antimalarial drug resistance. Results will be translated into policy and guidelines and ultimately ensure that healthcare providers and pregnant women have access to optimal treatment options for malaria in early pregnancy.

Keywords: maternal and child health,pregnancy,first trimester,platform trial,antimalarial therapeutic,safety,acceptability feasibility,cost effectiveness,implementation research,policy
Identity-Error: How Social Self-Evidencing Exposes Vulnerability to Falsehoods and Conspiracy Beliefs (IDENTITY-ERROR)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Ireland
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 1499093.0
EU funding (EUR): 1499093.0
Participants: 1
Project status: SIGNED

Understanding how people discern the “truthfulness” of information is of fundamental importance to science. However, the complexity of dynamic information processing in social environments has made it convenient to “silo” research at different levels of analysis (neurological, psychological, social). To overcome this, we need end-to-end modeling that explains when and why people are vulnerable to falsehoods and mistruth. IDENTITY-ERROR pursues a new methodological framework that integrates a social-identity approach with recent advances in computational modeling to socially embed the emotional and cognitive elements of epistemic processing. I propose that the experienced “truthfulness” of information is determined by a recursive process from individual (affect, cognition) to social (identity-structured information). A process of social-self-evidencing fits evidence to models in an identity-congruent manner by error-tuning, either rejecting evidence (common) or models (less common). Identity-imbued models of reality manage error, and in some conditions, objectively incorrect models are very effective error sinks (i.e., they allow good evidence to be easily rejected). This breakthrough will be advanced by harnessing the identity structure of social information to make predictive processing models scalable at the social level. This allows the parallel computation of (i) information reliability alongside (ii) the social costs of accepting it as true (i.e., social evidencing). Importantly, error dynamics in these models enable the integration of emotional influence. IDENTITY-ERROR will establish a new field of psycho-social identity modeling, optimized for understanding the social functions of maintaining falsehoods and conspiracies, and providing a firm basis for socially grounded health and science communication that is resilient to conspiracy theory and misinformation.
The role of developmental biases on the tempo of phenotypic evolution (EvoBias)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Portugal
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 172618.56
EU funding (EUR): 172618.56
Participants: 1
Project status: CLOSED

Understanding the mechanisms that generate phenotypic variation and their impact on the course of evolution is a central challenge in modern biology. The genetic architecture of development may limit or bias the phenotypic spectrum obtained after random mutation, deemed developmental bias. These phenotypic biases in turn may influence evolutionary trajectories. Despite the recognition of the importance of developmental biases in constraining and pacing evolution, there is no direct empirical evidence for this potential role. Here, I propose to tackle this key question using the ecologically-relevant avoidance to pathogens in the genetically-tractable organism Caenorhabditis elegans. To this aim, I will: (i) quantify and uncover mechanisms of developmental biases in avoidance behaviour; and (2) test the role of developmental biases on the tempo of phenotypic evolution. On the first objective, I will generate a novel panel of random mutant lines containing a transgene for whole-organism neuronal cell-fate identification, determine developmental biases in locomotor and avoidance behaviour, and uncover mechanisms of developmental biases. On the second objective, I will construct hybrid outbred populations with varying developmental biases to test their impact on the tempo of phenotypic evolution in an ecologically relevant scenario using experimental evolution. To achieve this, I will adopt an innovative interdisciplinary approach that combines my expertise in neurodevelopmental and behaviour genetics, quantitative genetics, genome-editing and know-how with the model C. elegans with that of the host lab in experimental evolution, behaviour ecology and host-pathogen interactions. Thus, promoting an active exchange of multidisciplinary expertise between the two parties. EvoBias will elucidate the role of developmental bias during the evolutionary process and its mechanisms in an ecologically-relevant scenario, and it will be a milestone towards my scientific independence

Keywords: developmental biases,mutational variance,experimental evolution,caenorhabditis elegans,evolution of behaviour,pathogen avoidance behaviour,host pathogen interactions
Relativistic Magnetic reconnetion in Atrophysical Plasmas (ReMAP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Belgium
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 200400.0
EU funding (EUR): 200400.0
Participants: 1
Project status: SIGNED

Astrophysical compact objects like neutron stars and black holes are surrounded by a hot gas of charged particle known as plasma. In these environments, we observe powerful phenomena, including pulsar wind nebulae, jets, and gamma-ray bursts. The mechanisms behind particle acceleration and high-energy emissions, particularly magnetic reconnection, are not fully understood. Magnetic reconnection, where magnetic field lines break and reconnect, is believed to drive particle acceleration up to ultra-relativistic speeds, but its detailed dynamics remain largely unexplored. Recent advancements in simulation techniques and observational capabilities make this an opportune moment to resolve key questions in high-energy plasma physics. This project will investigate relativistic magnetic reconnection and its role in particle acceleration and radiation production using advanced simulation methods, including Particle-in-Cell (PIC) simulations for kinetic modeling. The ECsim code will explore the initiation of magnetic reconnection, while the TRISTAN-v2 code will incorporate photon interactions and pair production. Alongside these simulations, an analytical model will be developed to predict reconnection timescales and verify the simulation results. These tools will study the onset of reconnection, particle trajectories, and the effects of radiative cooling, providing new insights into high-energy astrophysical processes.

Keywords: plasma astrophysics,high energy astrophysics,magnetic reconnection,plasma dynamics
Formation and Evolution of the Earth with Volatile Elements (FOREVER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: France
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 2494223.75
EU funding (EUR): 2494223.75
Participants: 1
Project status: SIGNED

The first 150 million years of the Earth’s history have led to the formation of the metallic core and the solidification of the magma ocean. During this period the chemical composition of the core and the bulk silicate Earth (BSE) were defined, setting the initial conditions for subsequent planetary-scale evolution. The volatile and atmophile elements (C, H, N, O, S) and noble gases (used as tracers) compose life molecules and control key atmospheric properties, thus contributing to the definition of habitable planets. These elements are abundant at the Earth’s surface but the planetary interior represent a much greater reservoir. Determining C, H, N, O, S and noble gases budget in both the core and the BSE requires experimental data at the deep magma ocean conditions, which is currently challenging. However, this information is critical for interpreting geophysical and geochemical observations on the distribution and cycling of volatile compounds. Here, we will conduct laboratory experiments to quantify the concentrations of these elements (into the core and the BSE) at the conditions that prevailed during core formation. We also aim to establish how the main phases of the lower mantle controlled the volatile budget during and immediately after magma ocean times by measuring the in-situ electrical and seismic profiles of volatile-bearing minerals. The quantitative constraints from our experimental studies will then be incorporated within innovative numerical convection models to determine the effect of volatiles on the thermal, rheological and melt fraction evolution of a cooling and crystallizing magma ocean, and also on the evolution of the primordial atmosphere of planets. Finally, these experimental constraints will be combined with geochemical and cosmochemical ones to build a new generation of models in which the formation of Earth and its atmosphere is viewed within a realistic context of the formation and evolution of our solar system.

Keywords: earth s core formation earth accretion noble gases hydrogen water carbon nitrogen sulphur lower mantle