Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Reconstructing the Past: Artificial Intelligence and Robotics Meet Cultural Heritage (RePAIR)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Research and Innovation actions
Countries involved: Germany,Israel,Italy,Italy,Italy,Portugal
Call: FET-Open Challenging Current Thinking (H2020-FETOPEN-2018-2019-2020-01, 2020)
Start date: 2021-09-01
End date: 2025-02-28
Duration (months): 42.0
Total project cost (EUR): 3522010.0
EU funding (EUR): 3522007.0
Participants: 6
Project status: SIGNED

Our goal with this project is to develop a ground-breaking technology to virtually eliminate one of the most labour-intensive and frustrating steps in archaeological research, namely the physical reconstruction of shattered artworks. Indeed, countless vases, amphoras, frescos and other ancient artefacts, all over the world, have not survived intact and were dug out from excavation sites as large collections of fragments, many of which are damaged, worn out or missing altogether. Reconstruction of small artefacts is typically done by experienced operators, possibly with the assistance of dedicated software, but when the number of fragments is large (say, of the order of thousands) manual or computer-assisted restoration is simply hopeless. This prevents a large fraction of the world’s cultural heritage from being openly accessible to scholars as well as the general public. By developing and integrating novel technologies in the fields of robotics, computer vision and artificial intelligence, we envisage a future where archaeology can deal effectively with reconstruction problems at an unprecedented scale and be able to bring back to life ancient artworks and masterpieces which would otherwise remain broken into pieces forever. Specifically, we aim to develop an intelligent robotic system which will autonomously process, match and physically assemble large fractured artefacts at a fraction of the time it takes humans to do. The level of ambition of our proposal poses several challenges that cannot be satisfactorily addressed with off-the-shelf technologies, and hence we shall develop brand-new solutions that will push the boundaries of research in the fields of robotics and computer vision. Our system will be tested over iconic case studies from the UNESCO World Heritage site of Pompeii, and one tangible outcome of the project will be to restore two world-renowned frescos which are now shattered into thousands of fragments and forgotten in storerooms.

Keywords: computer vision,robotics,cultural heritage,computer applications in archaeology
Smart Cultural Tourism as a Driver of Sustainable Development of European Regions (SmartCulTour)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Reflective societies - cultural heritage and European identity
Action type: Research and Innovation actions
Countries involved: Austria,Spain,Italy,Italy,Finland,Croatia,Belgium,Belgium,France,Netherlands
Call: Innovative approaches to urban and regional development through cultural tourism (H2020-SC6-TRANSFORMATIONS-2019, 2019)
Start date: 2020-01-01
End date: 2023-06-30
Duration (months): 42.0
Total project cost (EUR): 2980000.5
EU funding (EUR): 2980000.5
Participants: 10
Project status: SIGNED

SmartCulTour aims to support regional development in European regions, with special attention to rural peripheries and the urban fringe, through sustainable cultural tourism. The project redefines cultural tourism through a contemporary lens and provides a comprehensive measurement framework for supply, demand and impacts. In order to support knowledge-led destination management, a decision-support system (DSS) will be developed for wide-scale monitoring purposes across European regions. The DSS will synthesize both traditional and non-traditional data sources, the latter particularly related to big data analytics, thereby assisting smart regional development. Besides a contribution to conceptual development and cultural tourism measurement, the main objective of SmartCulTour relates to the facilitation of community-led rural development through field experimentation in 6 living labs. Prior to these living labs, a comprehensive desk research will identify significant sustainable cultural tourism policies, their impacts and critical success factors. These best cases will inspire a series of possible local interventions. Within the living labs, novel creative approaches to stakeholder engagement are tested, notably arts-based methods, serious games, and service design which will help to provide local context and support. A toolkit will be designed to help destinations implement local actions towards sustainable cultural tourism development. SmartCulTour will therefore contribute to theory development, empirical validation of best practices within a living labs setting, and procedural development, particularly by providing European regions with a set of strategies to optimally engage with stakeholders and co-create sustainable cultural tourism experiences.

Keywords: cultural tourism,sustainable urban and regional development,european regions,living labs,impact analysis,decision support system,impact measures,resilience,serious game,participatory approach
EMBedding Responsible Research And Innovation in Future and Emerging TeChnologiEs (EMBRACE)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Coordination and support actions
Countries involved: United Kingdom
Call: FET Innovation Launchpad (H2020-FETOPEN-2018-2019-2020-4, 2020)
Start date: 2021-05-01
End date: 2022-10-31
Duration (months): 18.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 2
Project status: CLOSED

Future and emerging technology (FET) research, as performed by EU FET and EIC, aims to create radically novel ideas and technologies that can disrupt and transform human lives, businesses and society as a whole. Such transformation can be greatly beneficial. At the same time work on FET can raise social and ethical concerns, linked to the processes of research and innovation, as well as their purpose and outcomes. The EMBRACE project will develop commercially viable services to integrate principles and practices of responsible research and innovation (RRI) into FET research as well commercialisation activities. It will draw from the broad range of activities related to RRI in the FET Flagship Human Brain Project. The successful and internationally recognised work on RRI in the HBP will provide the basis on which commercial services will be tailored for FET-related work. The EMBRACE project will address the following challenges applying appropriate methodologies: 1. To find out which specific ethical issues FET research faces, in particular during their commercialisation stage, EMBRACE will undertake a fact finding exercise. This will involve interviews with 40+ FET Launchpad project coordinators. 2. To address these challenges, EMBRACE will define appropriate RRI services. This will involve 3 focus groups on potential services. 3. The services will be validated by 6 service delivery trials (e.g. training courses, consultancy work) involving potential commercial partners. 4. The tested and validated services will be announced to all FET and EIC Pathfinder project participants to support market entry. EMBRACE will use the Observatory for Responsible Research and Innovation (ORBIT; www.orbit-rri.org), a not-for-profit spin-out company jointly owned by the University of Oxford and De Montfort University, as the mechanism for trialling, testing and delivering the services, thus ensuring long-term impact beyond the lifetime of the FET Launchpad funding.

Keywords: responsible research and innovation,ethics support,compliance management
The role of volatiles in the formation of magmatic iron oxide deposits (IRON_DEPOSITS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-01
End date: 2017-05-31
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

The formation of magmatic iron oxide deposit is closely related to the role of volatiles in magmas, especially in low-Ti magmatic systems (Kiruna-type). Volatiles have strong effect on phase equilibria, saturation of Fe-Ti oxides, and liquid immiscibility. They also control the magmatic-hydrothermal transition with implications for the remobilization of some strategic elements (P, Au, Cu, REE) by fluids. Volatiles are thus key components for the relation between Kiruna-type ores and Iron Oxides Copper Gold deposits. This project is an attempt to constrain experimentally the role of volatiles in magmas related to the formation of Kiruna-type iron deposits. We will study the development of liquid and fluid immiscibility, major and trace element partitioning between melts and fluids, and iron isotopes fractionation between minerals, silicate melts and fluids. The study will benefit from unique high pressure experimental and UV-femtosecond laser ablation-ICP-MS analytical facilities developed in Hannover. The objective is to constrain the conditions and the processes responsible for the concentration of iron in low-Ti volatile-rich magmatic systems and to identify the key-factors responsible for the enrichment of elements of economic interest.

Keywords: volatile,magma,iron oxide deposit,iron isotope,experimental geochemistry,silicate liquid immiscibility
Energetics of natural turbulent flows: the impact of waves and radiation. (FLAVE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: France
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-03-01
End date: 2024-08-31
Duration (months): 78.0
Total project cost (EUR): 1499094.0
EU funding (EUR): 1499094.0
Participants: 1
Project status: SIGNED

Turbulence in natural flows is an outstanding challenge with key implications for the energetics of planets, stars, oceans, and the Earth’s climate system. Such natural flows interact with waves, radiation or a combination thereof: surface waves and solar radiation on oceans and lakes, bulk waves and radiation inside the rapidly rotating and electrically conducting solar interior, etc. Standard simplified models often discard waves, radiation, or both, with dramatic consequences for the energy budget of natural flows: geostrophic models neglect waves, and Rayleigh-Bénard thermal convection considers heat diffusively injected through a solid boundary, in strong contrast with radiative heating. The purpose of the present multidisciplinary project is to develop a consistent and coupled description of natural flows interacting with waves and radiation, to properly assess their energy budget: • Because resolving surface waves in global ocean models will remain out-of-reach for decades, I will derive and investigate reduced equations describing their two-way coupling to the ocean currents, with timely implications for the upwelling of nutrients, the strength of the global ocean circulation and ultimately CO2 sequestration and the climate system. • Building on my recent advances in the field of rotating and magnetohydrodynamic turbulence, I will derive a set of reduced equations to simulate such turbulent flows in the vicinity of the transition where bulk 3D waves appear on a 2D turbulent flow. This approach will allow me to reach unprecedented parameter regimes, orders of magnitude beyond state-of-the-art 3D direct numerical simulations (DNS). • Finally, I will combine state-of-the-art DNS with a versatile experimental platform to determine the structure, kinetic energy and heat transport of turbulent radiative convection in various geometries. I will extrapolate the resulting scaling-laws to the ocean circulation, the mixing in lakes and the solar tachocline.

Keywords: turbulence,geophysical and astrophysical fluid dynamics
Direct reprogramming of human astrocytes into functional neurons in cerebral organoids derived from genome edited hiPSCs (Repro_organoid)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-03-01
End date: 2020-03-18
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

Work over the last decade has shown that the genetic programs underlying cell identity are still plastic in terminally differentiated cells. Direct lineage reprogramming takes advantage of this plasticity to induce cell fate conversions from one cell type into another. This is achieved by forced expression of specific fate determinants, usually transcription factors that regulate cell fate during development. This proposal will allow me to address the fundamental biological question whether human glia can be reprogrammed within a human tissue setting, and if so, whether this depends on their state of maturation. I propose to study the possibility of converting human glia into induced neurons within an in vivo-like tissue context. Towards this I will employ cutting-edge techniques such as generation of cerebral organoids from human induced pluripotent stem cells (hiPSCs) and genome-editing techniques to allow for inducible expression of reprogramming factors in human glia at different maturation stages within the cerebral organoids. In order to perform the hiPSCs genome-editing I will use CRISPR/Cas9 technology which will permit me to obtain stable, cell-type specific and inducible hiPSC lines. This novel and valuable genome editing strategy will facilitate the use of different reprogramming factors sets in order to optimize the reprogramming of glial cells into functional neurons. This study may pave the way for translating direct lineage reprogramming into new strategies for brain repair.

Keywords: direct lineage reprogramming,human astrocytes,hips cells,crispr,cas9,cerebral organoids
General aviation Rescue capacity IMprovement for the worldwide Adoption of a Safe Solution based on European GNSS (GRIMASSE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Innovation actions
Countries involved: Italy,Spain,France,United Kingdom,Senegal
Call: EGNSS Transport applications (H2020-GALILEO-GSA-2017-1, 2017)
Start date: 2017-11-01
End date: 2021-12-31
Duration (months): 50.0
Total project cost (EUR): 2678162.5
EU funding (EUR): 1925713.75
Participants: 8
Project status: SIGNED

Based on the observations that: - most of the aeronautical accidents involve General Aviation (GA) aircrafts, particularly the ones with a significant survival rate - most of the GA aircraft are not equipped with costly ELT but only not adapted PLB - GA accidents generate the majority of the workload of RCC and the operations where the response delay is the most critical to save lives Considering also that: - ICAO and C/S are doing significant standardization efforts to improve the in-flight transmission capability and performance for commercial aviation - There is now a new requirement for each flight to carry on-board an installed ELT or a PLB - The ICAO projects to evaluate the feasibility of an ADT adapted to other aircrafts than commercial ones (see GADSS ADT007 – Assess extending applicability to other aircraft operations) GA SAR issue appears to be critical. GRIMASSE proposes to develop operational concepts based on anchoring the Galileo SAR service in the SWIM information sharing concept implemented all around the world and in Europe in particular as SESAR. The main objectives of the projects are: - To improve the SAR detection and response to GA aircrafts and helicopters distress - To optimize the responsiveness of RCCs - To adapt the MCCs and MEOLUT to the data distribution of ELT-DT SAR alerts The project intends to develop 3 products: - SWIM applications to optimize the exchange of SAR information by RCCs and MCCs - MCC ELT-DT implementing functions to distribute ELT-DT messages - A cost-effective ELT-DT for GA including the ADT functionalities, easy to plug into the aircraft and with minor or no alterations to the aircraft The project is structured in 4 phases: · Collection of the needs (RCC, pilot, aero-club, MCC) · Definition and development of the system · Experimentations and demonstrations phase · Dissemination GRIMASSE will promote Galileo as the main actor of worldwide aviation safety.

Keywords: gadss,swim
Virtualization of Real Flows for Animation and Simulation (realFlow)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Germany
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-05-01
End date: 2020-08-31
Duration (months): 64.0
Total project cost (EUR): 1465603.75
EU funding (EUR): 1465603.75
Participants: 1
Project status: CLOSED

Besides their application in a very broad range of engineering disciplines, physically-based simulations have become a prevalent tool for all forms of computer-generated environments. Simulations of fluids are a particularly important area that has applications ranging from the design of aerodynamic bodies to the realization of impressive visual effects in movies. However, despite their extremely wide-spread use there are fundamental problems: a lack of practical flow capturing technologies and the inherent difficulties of resolving crucial features such as turbulence. These issues are show-stoppers preventing the area from realizing its full potential for animations and interactive environments. The goal of this research is to address these central problems: 1) by designing novel data-centric approaches for fluid simulations to enable re-use, and 2) by establishing an innovative pipeline for capturing flow motions yielding details that were previously unachievable. To this end, I plan to design algorithms that tightly integrate accurate physics solvers with methods for the reconstruction of motion from volumetric images. At the same time, I will work on novel structured representations that decompose complex flows into hierarchical space-time structures. These structured virtual counter-parts will not only enable powerful avenues for intuitive editing, but will also serve as a basis for robust and efficient data-driven fluid simulations. This virtualization of flows opens the door for interactive design tools and medical applications, allowing to incorporate complex physical constraints. In addition, this research could radically change the way we work with synthetic and captured flow data, and has significant potential to break new ground in terms of data-centric work-flows for fluid simulations.

Keywords: physically based animation,fluid simulation,data driven methods,flow capture
PREeclampsia risk stratification test: development of a suitable CALIbration framework for the analysis of a multiplex panel of endogenous compounds by LC-MS (PRECALI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2020-05-31
Duration (months): 24.0
Total project cost (EUR): 175866.0
EU funding (EUR): 175866.0
Participants: 1
Project status: CLOSED

PREeclampsia risk stratification test: development of CALIbration framework for the analysis of a multiplex panel of endogenous Compounds by LC-MS. Metabolomic Diagnostics (MDx) is an innovative company which is developing tests for pre-eclampsia in pregnancy. MDx consists of a team of scientists and entrepreneurs with clinical support. The enterprise and the experienced researcher propose to combine their expertise to support the development of a robust test for the risk stratification of preeclampsia. One of the key challenges in the product development is establishing the optimal way to perform the quantification of the metabolite targets underpinning the preeclmapsia test. In the case of risk stratification products, the predictive metabolite biomarker profiles are merely a perturbation in the levels of a set of endogenous occurring metabolites. As a result, the internationally well-established LC-MS test validation framework as known for bioanalysis is not readily applicable. The researcher’s doctoral dissertation focused on the development and subsequent validation of novel mass spectrometric assays for endogenous metabolites and she explored a novel validation strategy to overcome the limitations of the classic bioanalysis validation framework with regards to validation mass spectrometric assays for endogenous compounds. It would be difficult for MDx to find a candidate with a more relevant background for this project and it would be equally difficult for the researcher to find a company in Europe with such a perfect project to implement her expertise extensively. The scope of this project is the development of an appropriate quantification strategy for the product, with the following prerequisites: - 1. Delivering robust quantification data which can be fed to the product risk stratification algorithm - 2. Delivering robust quantification data in a format which can be accepted by key stakeholders

Keywords: metabolomics,biomarkers,pregnancy,preeclampsia,risk stratification,personalised medicine
Bringing a prophylactic Ebola vaccine to licensure (EBOVAC3)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Public-private partnerships
Destination: Innovative Medicines Initiative 2
Action type: Research and Innovation actions
Partnership: IMI2 (Art-187)
Countries involved: Belgium,Norway,France,France,Congo, The Democratic Republic of the,Netherlands,Sierra Leone,United Kingdom
Call: Ebola and other filoviral haemorrhagic fevers (Ebola+) programme: future outbreaks (H2020-JTI-IMI2-2015-08-single-stage, 2015)
Start date: 2018-06-01
End date: 2024-09-30
Duration (months): 76.0
Total project cost (EUR): 50979889.71
EU funding (EUR): 29402655.71
Participants: 10
Project status: SIGNED

The overall aim of EBOVAC3 is to support an essential part of remaining clinical and manufacturing activities required for licensure in the European Union (EU) and the United States (US) of a candidate heterologous prime-boost prophylactic vaccine regimen against Ebola virus disease that is under development at Janssen Vaccines & Prevention B.V. The intended target indication is defined as: “A prime-boost regimen with Ad26.ZEBOV as prime vaccine and MVA-BN®-Filo as boost vaccine indicated for the prevention of Ebola virus disease (EVD) caused by EBOV of the Zaire ebolavirus species in adults and elderly (aged ≥65 years), human immunodeficiency virus (HIV)-infected adults, and children aged ≥1 year.”

Keywords: ebola