Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
CONDUCTIVE MINERALS AS ELECTRICAL CONDUITS IN METHANE CYCLING (MIMET)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental B iology, Ecology  and E volution
Panel description: For all organisms : Ecology, biodiversity, environmental change , evolutionary biology, behavioural ecology, microbial ecology , marine biology, ecophysiology, theoretical developments and mod elling
Countries involved: Denmark
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-09-01
End date: 2028-09-30
Duration (months): 73.0
Total project cost (EUR): 1999760.5
EU funding (EUR): 1999760.5
Participants: 1
Project status: SIGNED

This proposal aims to gain a fundamental understanding of the impact of anthropogenic conductive particles on methane emissions. We recently showed that conductive particles are vital for the interspecies cross-feeding of a methane-producing consortium from the Baltic Sea. Previous to that, we showed that conductive particles accelerate methane production in synthetic dual-species consortia that typically function via direct electron transfer. Others showed that conductive particles may also stimulate anaerobic methane oxidation. For the latter, the reports are scarce and contradictory. It is mysterious how microorganisms interact with the conductive particles and how conductive particles affect the methane cycle in the environment. These knowledge gaps we will study here. We will use synthetic consortia, enriched environmental consortia, and whole sediment cores. We will identify marker genes for microbe-particle contacts by combining expression studies with targeted gene-deletion and physicochemical cell surface studies. The marker genes we can then use to track similar microbe-conductive particle associations in the environment. We will examine the link between increased anthropogenic particle input and methane emissions in environments from the Mediterranean to the Arctic where higher particle input is likely. I expect to deliver fundamental knowledge about the microorganisms involved in methane transformations by anthropogenically derived conductive particles.

Keywords: interspecies interactions microbe mineral interactions extracellular electron transfer direct interspecies electron transfer electromicrobiology
Monumentality in Europe with the Growth of Agriculture during the Neolithic (MEGALITH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France,United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 242260.56
EU funding (EUR): 242260.56
Participants: 2
Project status: SIGNED

The transition to farming provided the foundation for evolution of modern complex societies. This process, also known as a change from the Mesolithic to the Neolithic involved a radical shift in subsistence practices, from hunting and gathering to management of domesticated plants and animals. In north-western Europe, the development of farming was accompanied by a significant change in culture, with the construction of large megalithic monuments. This tradition emerged in France with the growth of farming here during the 5th millennium BC. It subsequently spread across the Channel to Britain and Ireland as farming arrived in these regions (from c. 4000 BC). Despite very many decades of excavation, the question of why monuments began to be constructed with the growth and expansion of agriculture remains uncertain. It is hypothesized that this tradition may have emerged through the interaction of Mesolithic communities and migrant Neolithic groups in north-western France, as farming developed in this region. How people were chosen for burial in these immense and impressive monuments remains unknown. It has been suggested that these tombs were used for the burial of a dynastic elite, indicating that the growth of agriculture provided the foundations for development of social inequality in Europe. A breakthrough in archaeological approach is needed to investigate these important questions. The methodology required must push beyond conventional excavation techniques to reveal how monuments were used, who is buried in these iconic monuments and why this tradition spread across north-west Europe. This project takes an interdisciplinary approach, combining multi-isotope and ancient DNA analysis to answer these questions. Using these methods MEGALITH will provide new direct evidence for population ancestry; social organization; gender relationships; mobility; settlement patterns and diet, to understand how monuments were used and why they were constructed.

Keywords: neolithic europe,dna,isotopes
ENsuring Secure and Safe CMD Design with Zero TRUST Principles (ENTRUST)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Maintaining an innovative, sustainable and globally competitive health industry
Action type: Research and Innovation actions
Countries involved: Luxembourg,Netherlands,Norway,Cyprus,France,Türkiye,Greece,Portugal,Switzerland,United Kingdom,Spain,Romania
Call: Enhancing cybersecurity of connected medical devices (HORIZON-HLTH-2022-IND-13, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 5633089.6
EU funding (EUR): 5633087.5
Participants: 21
Project status: SIGNED

Aligned with the guidelines of the Cybersecurity Act and the existing guidance on cybersecurity for medical devices, ENTRUST envisions a Trust Management Architecture intended to dynamically and holistically manage the lifecycle of connected medical devices, strengthening trust and privacy in the entire medical ecosystem. Even from the proposal stage, ENTRUST has identified gaps and necessary revisions of the current guidance (e.g., absence of post-market conformity and certification, real-time surveillance and corrective mechanisms – see 1.2.2). Towards that ENTRUST will leverage a series of breakthrough solutions to enhance assurance without limiting the applicability of connected medical devices by enclosing to them cybersecurity features. The project will introduce a novel remote attestation mechanism to ensure the device’s correct operation at runtime regardless of its computational power; will be efficient enough to run in also resource-constrained real-time systems such as the medical devices. This will be accompanied by dynamic trust assessment models capable of identifying the Required Level of Trustworthiness (RTL) per device and function (service) that will then be verified through a new breed of efficient, attestation mechanisms (to be deployed and executed during runtime). This will also enable us to be aligned with the existing standards on defining appropriate Protection profiles per device (especially considering the heterogeneous types of medical devices provided by different vendors with different requirements) including Targets of Validation Properties to be attested during runtime. The motivation behind ENTRUST is to ensure end-to-end trust management of medical devices including formally verified trust models, risk assessment process, secure lifecycle procedures, security policies, technical recommendations, and the first-ever real-time Conformity Certificates to safeguard connected medical devices.

Keywords: trust management,post market conformity and certification,verified trust models,risk assessment,secure lifecycle procedure,security policies
FUNCTUMUS: The Functional Turn in Music (FUNCTUMUS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 251578.56
EU funding (EUR): 251578.56
Participants: 1
Project status: SIGNED

Streaming, now the dominant format for music consumption, has fundamentally altered music’s role in daily life. With platforms encouraging users to engage with music as a tool for mood regulation and activity enhancement through curated playlists and streams, this shift has created whit might be termed a functional turn in music. However, not all music is created with a specific function in mind, leading to the appropriation and repackaging of existing genres for functional purposes. Despite this growing trend, the broader effects of this transformation on the musical practices of listening, production, and curation remain under-explored. FUNCTUMUS addresses this gap by investigating the functional appropriation of music through a case study of lofi hiphop (LFHH). Originating in the early 2000s, LFHH was rebranded in the 2010s as “music to relax/study to” by online curators, and the rhythms, grooves, and compositional structures of subsequent LFHH have evidently adapted to fit this new functional role. The functional appropriation has also reshaped practices of listening, production, and curation associated with the genre, causing friction between its functional and creative dimensions. FUNCTUMUS builds on these observations to examine the functional appropriation of LFHH from the perspectives of listeners, producers, and curators, whilst also accounting for its cognitive-behavioural effects and the hegemonic systems of power and in which it is embedded. The study employs Netnographic observation of online communities central to LFHH and qualitative interviews with listeners, producers, and curators, supported by musical analysis. A unique theoretical framework, drawing from Musicology, Sociology, and Semiotics, underpins the research, offering a comprehensive exploration of how digital streaming reshapes the form and function of contemporary music.

Keywords: digital streaming,music streaming,functional music,semiotics,hip hop,genre
SUstainable EuroPean Rare Earth Elements production value chain from priMary Ores (SUPREEMO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Innovation actions
Countries involved: Norway,Belgium,United Kingdom,Slovenia,Netherlands,Sweden,Slovakia,France,Czechia
Call: Technologies for processing and refining of critical raw materials (IA) (HORIZON-CL4-2023-RESILIENCE-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 7125634.48
EU funding (EUR): 6408127.26
Participants: 12
Project status: SIGNED

SUPREEMO aims to establish the first pre-commercial Rare Earth Elements (REEs) production value chain (TRL7) using European (EU) primary resources as feedstock, developing sustainable, cost-competitive processing, refining and Rare Earth (RE) Permanent Magnet (PM) production technologies in a responsible way complying with local and international safety regulations. This will contribute in securing REE materials supply for the EU industry and strategic sectors which depends 100 % on Chinese imports. The largest end-user of REEs is the PMs industry, that contain neodymium, praseodymium, and dysprosium as key elements to produce high energy-efficient motors, which are vital for electric mobility and renewable energy technologies. SUPREEMO will exploit the European primary resources from two major EU sites: Fen deposit Norway (largest carbonatite deposit in EU) with >200 Mtonne grading 1.2-1.5 % Total Rare Earth Oxides and secondly, exploring extraction technologies related to deposits from uranium extraction in the Czech Republic, technologies which is also intended for implementation in direct extraction during uranium beneficiation related to nuclear energy supply chains. SUPREEMO will capitalise on technologies demonstrated in previous projects to develop innovative, environmentally friendly, socially and economically sustainable REEs processing technologies. During phase 1, the partners will optimise the stand alone technologies to elucidate the final integrated process flowsheet with the best processing parameters in phase 2, guided by LCA and LCCA. This will be validated at the piloting activities in phase 3. Finally, the production of 50-100 kg of REO at similar cost to commercial value from Chinese production will be demonstrated at TRL7 by processing ~ 10 tonnes of ores, and the production of Rare Earth Alloy for the manufacturing of 50 kg PMs. Results will be communicated and disseminated to key stakeholders and a concrete first business plan will be set to attract more investors and stimulate a competitive, resilient and sustainable REEs production value chain ready for full-scale deployment in the EU market.

Keywords: permanent magnet,rare earth elements,rare earth element alloy,rare earth primary extraction,critical raw material,rees sustainable value chain,recovery technologies,green transition
Nanoagent-based three-method treatment for atherosclerosis: Combination of thermal, mechanical, and drug-based methods (NanoTAS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-02-01
End date: 2025-01-31
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: CLOSED

The aim of NanoTAS is to propose a novel three-method treatment for the atherosclerosis (AS) disease based on nano-structured agents (NAs), which incorporates three kinds of methods into a single one: 1) Thermal treatment, 2) Mechanical treatment, and 3) Anti-AS drug-based treatment. The NAs employed in the NanoTAS are proposed to have a novel composite structure including magnetic agents (ferrite-based nanorods; FNRs) and plasmonic agents (Au nanostars; AuNSs). Thermal treatment is accomplished through magneto-photo thermal therapy (MPTT), a combination of magnetic hyperthermia therapy (MHT) using FNRs under alternating magnetic field (AMF) and photothermal therapy (PTT) using AuNSs under near-infrared laser (NIR-laser) while mechanical treatment is performed through rotation of NAs (by their magnetic part i.e. FNRs) under rotating magnetic field (RMF). The NAs also load anti-AS drug and deliver it to target sites through a biocompatible and thermo-sensitive polymer. Accordingly, the specific objectives of NanoTAS can be summarized as: Oi) Decreasing the inflammation in blood vessels involved in the AS through thermal treatment (MPTT). Oii) Targeted release of anti-AS drug using a thermo-sensitive mechanism triggered by thermal treatment. Oiii) Breaking and abrading plaques using mechanical treatment through rotation of NAs under RMF. The objectives are achieved through applying the external stimuli on the drug-loaded NAs, during the following steps: Step 1) Applying both AMF and NIR-laser: This is a two-purpose step in which thermal treatment is accomplished aiming both decrease in inflammation (Oi) and drug release (Oii). Step 2) Applying RMF: This step is applied for breaking and chipping the structure of plaques (Oiii). Step 3) Repeating the step 1: This step is a supplementary one to decrease in remaining inflammation (Oi).

Keywords: magnetic hyperthermia therapy photothermal therapy magnetic nanorod au nanostar drug release mechanical treatment biocompatibility atherosclerosis
Feedback Levitation on an Inverted Potential: A new tool for macroscopic quantum physics, sensing and information thermodynamics (FLIP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-05-01
End date: 2025-06-30
Duration (months): 26.0
Total project cost (EUR): 183600.96
EU funding (EUR): 183600.96
Participants: 1
Project status: CLOSED

The control of levitated mesoscopic objects has developed into a flourishing field promising significant advances in sensing technologies, stochastic and quantum thermodynamics as well as macroscopic quantum physics. While optical levitation has already reached operation in the quantum regime, internal heating by absorption is a major challenge. With FLIP (Feedback Levitation on an Inverted Potential) we propose an original solution: dark field optical detection plus active feedback control provides position stabilization (without additional confining potential) and cooling to a close-to-pure quantum state without absorption. FLIP goes beyond the state of the art in several ways. It provides access to quantum control of absorbing objects in high vacuum (e.g. spin mechanics with NV-centers). It opens the door to large quantum superpositions via free-fall experiments with internally cold particles. It enables sensing and information thermodynamics with unstable potentials in the quantum regime. Following the recent demonstration of quantum limited position readout, real-time state reconstruction and feedback cooling to the ground state, it is the ideal time to develop levitation in the dark optical field. A controllable inverted potential for levitated particles is available in the host group, such that the project can be implemented from day zero and expanded towards a 3D dark quantum trap. Close collaboration with the Aspelmeyer group (partner group) and Prof. Kugi (ACIN) who jointly achieved feedback based ground state cooling will facilitate the implementation of FLIP. My expertise in FPGA-based optical feedback control puts me in a perfect position to implement FLIP. At the host group, I will expand my background in optomechanics, and quantum optics. Finally, continuing my research in information thermodynamics using FLIP, the proposed research will, if successful, sharpen my unique research profile and open fruitful research directions for my future career.

Keywords: optical levitation,information and thermodynamics,feedback control,quantum systems,sensing
Dementia/Alzheimer Drug Attributed to Cystatin-C and other mutations – precision medicine drug development (DNACA)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Iceland
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-03-01
End date: 2025-02-28
Duration (months): 24.0
Total project cost (EUR): 3571875.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

With an aging population and >55 million dementia cases worldwide; treatments are more needed than ever. However, effective treatments are lacking, with solutions only stalling dementia progress and no real disease-modifying effect. ATI has developed AT-001, a new drug with the potential to stop and revert the disease, and to delay its onset. AT-001 has been developed through the DNACA precision-medicine based platform, which applies Big Data mining and Deep Learning/AI algorithms to identify patients with validated biomarkers. AT-001 is different in that it prevents aggregation of amyloid/tau proteins, common in many types of dementia. Phase IIa clinical trials have shown strong effects in the treatment of HCCAA. We will now carry out a registration trial for commercialization in Iceland and POC studies in Europe to obtain NDA in familial dementia, thereby informing the treatment of Alzheimer’s Disease (60% of dementia cases), potentially changing the lives of millions for the better.

Keywords: precision medicine,big data,therapy,genomics,genetics,dementia,alzheimer s disease,hereditary cerebral amyloid angiopathies,drug development,biobank
Highly efficient delamination technologies to recover and reuse metals, glass, polymers from end-of-life photovoltaic panels (EVERPV)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: France,Italy,Belgium,Switzerland,United Kingdom,Spain,Lithuania,Germany
Call: Recycling end of life PV modules (HORIZON-CL5-2022-D3-03, 2022)
Start date: 2023-09-01
End date: 2026-08-31
Duration (months): 36.0
Total project cost (EUR): 6104883.25
EU funding (EUR): 5367184.0
Participants: 20
Project status: SIGNED

EVERPV’s objective is to provide EU with efficient solutions for a sustainable treatment of end-of-life PV panels and recovery of high purity and high integrity materials. Based on the grinding of PV panels waste from the backside and/or the use of IR lamps heating, EVERPV will demonstrate two innovative technologies to delaminate the different layers of the PV panel. Combined with recycling processes, it will enable to recover glass with less than 1% impurities, encapsulant and backsheet polymers with a purity over 99%, and silver with a purity of 99%. Besides, the project will cluster with other EU-funded consortia already addressing the recycling of silicon (e.g. PHOTORAMA) to provide with a global solution. The new delamination technologies will be respectively demonstrated at ENVIE recycling plant and at 9TECH to reach TRL7. The technology demonstrated during EVERPV project targets to process more than 3000 tons of solar panels per year, thus recovering enough raw materials recovered to produce more than 350 000 new panels per year by 2030. EVERPV will finally demonstrate the potential for reusability of recovered materials in several industrial value chains in particular in the PV industry. The project will lead a strategic analysis on the potential of new EoL panels circular value chains based on estimated PV waste generation together with environmental and societal impact assessments. EVERPV has gathered a consortium of 16 participants from 8 countries whose expertise ranges from solar PV materials and recycling processes (CEA, CSEM, ENEA, TEC), recyclers (ENVIE, 9TECH), process industries and materials suppliers (SGB, DTF, DPL, JBR), PV modules manufacturing (VAL), collecting and waste treatment organizations (SOREN, ERION), policy-making, business and training facilitators (SPE, UNITAR, BI).

Keywords: photovoltaic panels,waste,recycling,delamination,silver,polymers,glass,ir irradiation,grinding,closed loop