Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Trajectories in the Byzantine fabric of time: philosophical and narratological approaches to temporal (dis)order in middle Byzantium (ByzTime)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2023-09-30
Duration (months): 24.0
Total project cost (EUR): 186167.04
EU funding (EUR): 186167.04
Participants: 1
Project status: SIGNED

ByzTime proposes to investigate the Byzantine concept of time from the vantage point of three distinct yet interrelated literary genres: philosophical treatises, apocalyptic prophecies, and historiographical narratives. The aim is to establish new and holistic insights into the elusive fabric of time conceptions during the later middle Byzantine period (11th– 13th c.). This timeframe allows us to consider one of the most productive periods of Byzantine thought while taking into account the disparate availability of different kinds of textual sources, namely (1) philosophical treatises that discuss the notion of time and eternity, (2) medieval Greek apocalypses that describe the end of times, and (3) historiographical narratives of the Komnēnian era, which advance various temporal strategies in narrating the course of events. The philosophical treatises will be analyzed in terms of their argumentative validity, historical significance, and conceptual approaches to time, while the historiographical and prophetic material will be examined regarding the literary strategies of narrating time, aspects in narrative speed, the (ir-)regularity of verb tenses, typological layers, and temporal motifs. The diversity of the sources and the nature of the project’s goals necessitate an interdisciplinary approach that combines Byzantine history, literary criticism, palaeography, philology, philosophy, religious studies, and digital humanities. ByzTime will produce 12 deliverables, including the participation in two international conferences and the publication of six peer-reviewed articles. Among the publications will be the critical edition of five treatises by the middle Byzantine philosopher John Italos and editiones principes of three Byzantine prophecies. A scholarly symposium on “Time in Byzantium” will also be organized. Ultimately, ByzTime promotes the “temporal turn” in Byzantine studies through the multidisciplinary investigation of the middle Byzantine notion(s) of time.

Keywords: byzantine intellectual history,history of philosophy,apocalyptic studies,byzantine historiography,manuscript studies,critical,digital editions,concept of time
Satellite-based Wetland Observation Service (SWOS)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Developing comprehensive and sustained global environmental observation and information systems
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Spain,Germany,Belgium,Greece,Sweden,France,France,Netherlands,Netherlands,Senegal,United Kingdom
Call: Making Earth Observation and Monitoring Data usable for ecosystem modelling and services (H2020-SC5-2014-two-stage, 2014)
Start date: 2015-06-01
End date: 2018-11-30
Duration (months): 42.0
Total project cost (EUR): 4979189.36
EU funding (EUR): 4979189.36
Participants: 15
Project status: CLOSED

The objective of the project SWOS is to develop a monitoring and information service focussing on wetland ecosystems. Globally wetlands are the ecosystems with the highest rate of loss. This is alarming, considering their significance as biodiversity hotspots and ecosystems with a central role in the water cycle, including improving water quality and reducing water scarcity, in climate regulation and the economic benefit gained from using their services. A key limitation to their more effective conservation, sustainable management and restoration is the missing knowledge underpinning the application of European policy by Member States. Under the Biodiversity Strategy, Member States have recently committed to the mapping and assessment of ecosystem services (MAES); this provides a key instrument for an improved integration of wetlands in policy. SWOS will take full advantage of the Sentinel satellites and integrate results from the ESA Globwetland projects. Status maps and indicators, as well as near real-time observations will allow the assessment of biodiversity and the monitoring of dynamic changes in an unmatched temporal and spatial resolution. The Service Portal will allow the integration and web-based analysis of new maps and in-situ measurements and provide a unique entry point to locate, access and connect existing information and databases. It follows a GEOSS compatible data-broker approach and adopts international standards. SWOS contributes to establishing a Global Wetland Observing System, as requested by Ramsar, it will facilitate local and EU monitoring tasks and input into international reporting obligations. SWOS will position Europe in a leading role for wetland activities within the GEO ecosystem, biodiversity, water, land cover tasks. The direct involvement of users working at different scales and support of key user organizations ensures the usability and acceptance of the service, the harmonization with related activities and a long-term impact.

Keywords: wetlands,ecosystem service,biodiversity,maes,policy implementation,geoss,users are partners,multi scale monitoring,indicators,sentinel satellite data,service portal,sw toolbox
Machine Translation Impact on Language Learning (MTrill)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-04-25
End date: 2021-07-16
Duration (months): 24.0
Total project cost (EUR): 184590.72
EU funding (EUR): 184590.72
Participants: 1
Project status: CLOSED

The MTrill is a process-oriented research that aims at investigating how online freely available Machine Translation (MT) systems are impacting the acquisition and processing of English as a second language. The research will shed light on issues involving a central aspect of language acquisition: the so-called language binding, i.e., the ability to combine single words properly in a grammatical sentence in a second language. To pursue this goal, a syntactic priming experiment will be carried out in which participants will be tested as whether they produce the same syntactic structures that had been previously seen during a translation task using a MT. The project brings a brand-new methodological approach within MT process-oriented evaluation research and it goes beyond the existing state-of-the-art approaches since it will focus on translation processing complemented by product analysis (oral production). The project will be conducted under the supervision of Professor Andy Way and Doctor Monica Ward in the ADAPT Centre based in Dublin City university. A four-months secondment will be carried out in the Max Planck Institute of Psycholinguistics (MPI) in Nijmegen, The Netherlands, in the Neurobiology of Language research group under the supervision of Professor Peter Hagoort. The knowledge acquired during the secondment will be consolidated in the return phase through implementation of the experiments carried out for this project as well as through teaching and co-supervision activities. Results of this research will be disseminated through conferences and journal paper publications and will be communicated to multiple audiences through articles published in non-academic magazines, blogs and social media. The fellowship will attract academic networking opportunities, skill-set improvements and a personal and professional transformative experience to the researcher since it will establish her as the new leading light in research of an interdisciplinary field.

Keywords: language learning,syntax,psycholinguistics
Nano Diamond Powder Additive for Cosmetics (Diacosm)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Türkiye
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Appsilon Diamond Works proposes a new and innovative material for the cosmetics industry, the Nano Diamond powder “DiaCosm”, with surface modified Nano Diamond particles in order to provide greater anti-aging effects, deeper penetration, healthier experience and added value. As the current generation target the premium and effective products in the ever growing cosmetics market, a product that is able to provide excellence and effectiveness at the same time is needed. This is where the diamond shines. Appsilon excels in lab-grown diamond synthesis and infused its profession into cosmetics additives, thus created DiaCosm. DiaCosm nano diamond powder additive will provide penetration via high surface energy and low particle sizes, thanks to our novel methods of surface modification, pre and post treatments. But our nano diamond powder is purified of heavy metals and other impurities unlike standart powders in the market, therefore will provide a healthy experience. Once purified, diamond is inherently biocompatible. Our nano diamond is treated to have nano size particle sizes, to be able to penetrate the skin, the first requirement of cosmetic additives in term of performance. It is also surface modified to alter the surface energy, to carry and transport the actives in the cosmetics, to provide a better performance. Our production also involves recycling jewelry cuts from rough diamond we produce, therefore our raw material supply line is in the company and completely environmental. There are already a few diamond powder users in the cosmetics market, but there are certain problems with those. Appsilon identified the market, the customer, the bussiness model, developed a product that satisfies the need of the bussiness and therefore proposes the DiaCosm to the European Community.

Keywords: nano diamond,diamond powder,skin penetration,performance,surface energy,biocompatible
Radiomics of lung cancer (RAIL): non-invasive stratification of tumour heterogeneity for personalised cancer therapy (RAIL)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Netherlands
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-2-2014, 2014)
Start date: 2015-06-01
End date: 2020-03-31
Duration (months): 58.0
Total project cost (EUR): 2427593.75
EU funding (EUR): 2427593.75
Participants: 1
Project status: CLOSED

Lung cancer is the most common cause of death from cancer worldwide with 1.59 million deaths annually. It also places the highest economic burden of all cancers on the EU with EUR 18.8 billion. Non-small cell lung cancer (NSCLC) comprises 85% of all lung cancer cases. The current clinical routine to guide treatment for NSCLC patients is primarily based on the TNM staging system founded in 1958, mainly to look at surgical operability. However, TNM-based evaluation, nor doctors prediction do not provide an accurate prognosis. The heterogeneity between patients (inter-patient), tumours (inter-tumour) and even within one tumour (intra-tumour) underlies these highly variable prognosis and presents a major clinical challenge. There is a lack of easy to perform, ‘actionable’ biomarkers to stratify NSCLC patients which results in i) under-treatment in 20% of NSCLC patients leading to disease progression and ultimately death, ii) over-treatment in 30% of NSCLC patients which reduces the quality of life of patients and places an economic burden on the healthcare system and iii) ineffective clinical trial design, due to lack of optimal stratification, which requires very large, costly clinical trials to be performed in order to bring new therapeutic strategies to the market. ptTheragnostic has developed breakthrough technology, called “Radiomics”, which was recently published in Nature Communications, which enables patient stratification through the use of imaging biomarkers acquired from routine CT & PET imaging (see animation on www.pttheragnostic.com). In Radiomics for lung cancer (RAIL) we will validate and qualify a multi-site level I imaging biomarker together with a ready-to-use application to deliver more accurate prognostic information, personalise treatment for NSCLC patients, reduce healthcare costs by EUR 500+ million and enable efficient clinical trial design.

Keywords: radiomics,imaging biomarker,lung cancer,prognosis,nsclc
Women at the Edge of Empire: Female Social Identity in the Lower Danube in 4th-6th Centuries AD (WAEE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-08-28
End date: 2020-08-27
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The influence of migration and intercultural contact on identity formation is a topic of significant contemporary concern, yet it also took place in the past. Women at the Edge of Empire (WAEE) examines how the identities of migrant women, and local women married to migrant men, responded to intercultural contact at the eastern border of the Late Roman Empire (4-6th centuries AD). The Danube frontier is conventionally seen as a highly militarised environment and to-date women have been largely invisible, yet women were integral to the cultural melting pot that formed between Romans and nomadic peoples at this critical crossroads in human history. This innovative project draws together human osteology, stable isotopes, mortuary behaviour, material culture and epigraphy to focus on the people themselves. It employs series of analytical scales in order to integrate population-wide patterns with information about specific individuals to determine how large-scale transformations had an impact on individual lives by i) creating large regional datasets to identify both regional patterns in gender ideals and diversity in social practice ii) distinguishing non-local (migrant) and local women (of nomadic affiliation and Roman) iii) drilling down into the data to tell the stories of specific individual women through the construction of detailed osteobiographies in order to create individual understandings of the effect of migration and intercultural contact on female identities on both sides of the border of the late Roman empire from the Danube Delta to the Iron Gates. Project findings are disseminated to a range of target audiences including through peer-reviewed journal articles, conference presentations and an online exhibition featuring the women’s stories to engage the public, including women from modern migrant communities

Keywords: late antiquity,social identity,mortuary practice,osteobiography,intercultural contact
Selection of human iPSC-derived cardiomyocytes by sinGle cell geNe expression and pAtch clamp for a maTUre caRdiac modEl (SiGNATURE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-02-01
End date: 2022-01-31
Duration (months): 24.0
Total project cost (EUR): 187572.48
EU funding (EUR): 187572.48
Participants: 1
Project status: CLOSED

The incidence of cardiac arrhythmias in Europe is increasing because of aging and unexpected side effects of drugs, such as chemotherapeutics. To understand mechanisms underlying these conditions requires reliable preferably human models. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are presently good candidates since they share the genome of the individual from whom they are derived and can thus recapitulate genetic, ethnic and gender contributions to the cardiac disease phenotypes. However, their immature state and high inter- and intra-line variability is limiting their value as preclinical models. In the proposed project, I will address these issues through an interdisciplinary approach combining a unique 3D culture maturation system developed in my host lab with my expertise in electrophysiology. I will characterize gene expression and electrical properties of single cardiomyocytes simultaneously with view to directly correlating genes with function and identify molecular markers associated with the functionally mature cardiac phenotype. Two genetic cardiac diseases (one caused by an imprinted gene, the other by a postnatally expressed splice variant) for which the host already has hiPSC lines, will be used as proof of concept that hiPSC-CM maturation in this system is sufficient (i) to reveal disease phenotypes not evident in conventional culture and (ii) to identify molecular markers suitable for selecting mature hiPSC-CMs for drug testing. Overall, this project will provide the first functionally-relevant gene signature of (mature) hiPSC-CMs, and thus be an important advance in modelling all cardiomyocyte autonomous cardiac diseases more precisely for (personalized) drug screening. The outcome will be available to academic and private researchers to enhance rates of drug discovery and safety, and promote hiPSC-CMs as validated adult cardiac models to replace, at least in part, the use of animal models.

Keywords: human cardiac model,cardiac arrhythmia,hipsc derived cardiomyocytes,cellular electrophysiology,cardiac disease modelling,drug testing
Solvated Ions in Solid Electrodes: Alternative routes toward rechargeable batteries based on abundant elements (SEED)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-06-01
End date: 2025-05-31
Duration (months): 60.0
Total project cost (EUR): 1997811.0
EU funding (EUR): 1997811.0
Participants: 1
Project status: SIGNED

Storing large amounts of electrical energy is a major challenge for the forthcoming decades. Today, lithium-ion batteries (LIBs) are considered the best option for electric vehicles and grid storage but these rising markets put severe pressure on resource and supply chains. The principle of LIBs is based on solid electrodes separated by a liquid electrolyte between which Li ions are reversibly exchanged during charge and discharge. The efficient Li+ transport in the different phases and across the interfaces is essential for achieving a good performance. A fundamental difference between ion transport in solid phases and ion transport in solutions is that the ions are “naked” in the solid phase but solvated in the liquid phase. Recently major efforts have been initiated to adopt the successful LIB concept to other working ions such as Na+, K+, Mg2+, Ca2+ or Al3+. This is motivated by the promise of lower cost thanks to their abundance as well as in some cases higher energy density. The progress, however, is limited mainly due to an unfavourable mismatch between the solid electrode host structures and the ion radii or too large charge/radius ratios. Especially multivalent ions lead to severe lattice polarization frustrating ion mobility in solid electrodes. This project aims at a radically different concept, i.e. instead of “naked” ions, solvated ions will be intercalated into the electrodes. Solvent co-intercalation is traditionally considered as highly detrimental. Latest results, however, question the generality of this argument. The SEED project will explore the concept of using solvated ions in solid electrodes for the reversible storage of a variety of ions. As the solvation shell acts as electrostatic shield and can be tuned in its composition, lattice polarization can be minimized. Using this effect, the SEED project finally aims at enabling reversible charge storage of multivalent ions in host structures with properties far beyond current state-of-the art.

Keywords: electrochemical energy storage,batteries,intercalation compounds
Fundamental Problems at the Interface of Combinatorial Optimization with Integer Programming and Online Optimization (ICOPT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Switzerland
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-11-01
End date: 2024-10-31
Duration (months): 60.0
Total project cost (EUR): 1443422.0
EU funding (EUR): 1443422.0
Participants: 1
Project status: SIGNED

The goal of this proposal is to leverage and significantly extend techniques from the field of Combinatorial Optimization to address some fundamental open algorithmic questions in other, related areas, namely Integer Programming and Online Optimization. More precisely, we focus on the following three thrusts, which share many combinatorial features: - Integer programming with bounded subdeterminants. - Expressive power of mixed-integer linear formulations. - The matroid secretary conjecture, a key online selection problem. Recent significant progress, in which the PI played a central role, combined with new ideas, give hope to obtain breakthrough results in these fields. Many of the questions we consider are long-standing open problems in their respective area, and any progress is thus likely to be a significant contribution to Mathematical Optimization and Theoretical Computer Science. However, equally importantly, if progress can be achieved through the suggested methodologies, then this would create intriguing new links between different fields, which was a key driver in the selection of the above research thrusts.