Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A role for nuclear pore complexes in chromatin organization during early development? (NPCChr)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-03-01
End date: 2018-04-24
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

During differentiation, cells undergo large-scale chromatin rearrangement, notably with the establishment of heterochromatin blocks at the nuclear periphery during the epiblast stage of development. Concomitantly, hundreds of genes are relocated to and from the nuclear periphery and their position is correlated with their expression levels. Most of these genes are associated with regulation of pluripotency, suggesting that the association of fLADs to the NL is a key parameter for proper embryonic development. Recent work of the host lab using synthetic activators showed that the chromatin rearrangement is responsible for the relocation of these genes. However, the mechanisms that govern this chromatin rearrangement are largely unknown. Here I propose to test whether a modulation of nuclear pore density allows chromatin reorganization during differentiation of embryonic stem cells (ESCs) into epiblast stem cells (EpiSCs), laying the groundwork for future analysis in vivo during embryonic development. As a complementary approach, I will determine the mechanisms that prevent heterochromatin formation at nuclear pore complexes. The use of state of the art techniques such as super-resolution microscopy, genome mapping and a multidisciplinary approach combining biology and physics will allow me to understand the role of nuclear pore complexes in the regulation of genome organization.
The nanoscale control of reactive fluids on geological processes within the solid Earth (nanoEARTH)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2019-12-01
End date: 2025-05-31
Duration (months): 66.0
Total project cost (EUR): 1572500.0
EU funding (EUR): 1572500.0
Participants: 1
Project status: SIGNED

Fluid-driven mineral reactions chemically modify enormous portions of the Earth’s crystalline lithosphere. These reactions drive fluid-mediated rock transformation processes that governs the stability of mountain belts, the formation of hydrothermal mineral deposits and the sequestration of anthropogenic CO2 as well as many other processes. I propose that contrary to our current thinking, the re-actions themselves are driven by self-promoting nanoscale transport phenomena. Existing geological frameworks lack a quantitative understanding of mechanisms that control the rates of reactive fluid-rock interaction. This is because they do not account for the pervasive influence of nanoscale dynamics on the redistribution of elements within geological materials. The nanoEARTH project will solve this by defining the predominant transport processes occurring in mineral nanopores and the dynamic behaviour of fluid-rock interaction. To achieve the nanoEARTH aims and break through current limitations in our understanding of fluid-rock interaction, I will use my expertise in the multi-scale physics of geological processes. I will combine (1) novel nanoscale experiments that will establish transport mechanisms through natural and synthetic mineral nanopores and (2) unique in operando observations of fluid-driven mineral transformations at multiple length scales with (3) molecular-to continuum-scale transport modelling that is (4) constrained by geological observations. Through this integrative strategy, I will deliver new knowledge to redefine how the reaction of fluids with minerals self-generates a mode of transport that mobilises elements and controls the rates of fluid-driven transformation. This will impact geoscience research well beyond the project duration and bring the nanoscience of geological processes a quantum-leap forward in defining it as an integral part of solid Earth science.

Keywords: fluid rock interaction,nanogeoscience
DRONYTHING: ULTRA PRECISE AIRCRAFT INSPECTIONS (DRONYTHING)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-06-01
End date: 2018-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Dronything S.L. is a privately held company founded in Spain with the vision of guaranteeing that every aircraft can fly more and do what they are best at – helping people fly while spending less time in the hangar. After successfully piloting the prototype version of Dronything’s technology, the team can confirm the capability of its breakthrough product to open new markets in Europe with the potential for rapid growth. By pursuing the present feasibility study, the management team aims to improve its understanding of international market conditions and the associated risks that need to be considered as the company develops a deeper business plan for rolling out and scaling up Dronything as a marketable innovative solution. SME Instrument Phase-1 and Phase-2 will be extremely beneficial in helping the company to accelerate development and attain the targeted market penetration of the Dronything solution, boosting the company’s growth to 130 employees and € 78,820,000 in revenues by 2025.

Keywords: maintenance,inspection,aircraft,drone,innovation
(C)ADR: Novel cooling system for the cryogen-free, continuous, and fully automatic generation of very low temperatures near absolute zero. (CADR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2020-10-01
End date: 2023-03-31
Duration (months): 30.0
Total project cost (EUR): 2168375.0
EU funding (EUR): 1517862.5
Participants: 1
Project status: CLOSED

Low temperatures close to absolute zero (0 degrees Kelvin) are required for materials science, detectors for the aerospace and military sector, quantum computing, and quantum electronics. These temperatures are commonly achieved by using cryogenic liquefied gases (cryogens), such as liquid helium (He). However, there are a numbers of problems related to the use of these cryogens which include the oligopoly of He-3, high costs of cooling machines (€ 300-600k), and safety problems. To solve these pains, kiutra has developed a cryogen-free, continuous, and fully automatic refrigeration system based on a cryogenic magnetic cooling process known as (Continuous) Adiabatic Demagnetization Refrigeration - (C)ADR. (C)ADR uses widely available and low-price cooling media, saving € 20-40k/year in comparison with typical refrigeration systems that use He-3. Moreover, the system has a complete modular and customizable design, as it can be extended with multiple units according to the cooling requirements. It also offers a wide and stable temperature range while being easy to operate and hazard-free, thanks to the elimination of cryogens. kiutra, founded in 2018 in Germany, builds easy-access turn-key refrigeration solutions. Their cooling devices combine magnetic refrigeration and closed-cycle pre-cooling to provide cryogenic temperatures without cryogens. kiutra is currently funded by “EXIST Transfer of Research”, and has raised almost € 2M to date.

Keywords: cryogens,cooling system,quantum technology,quantum computing,quantum communication
Territorial Responsible Research and Innovation Through the involvement of local R&I Actors (TeRRItoria)

Framework: Horizon 2020 — Science with and for Society
Programme: Integrate society in science and innovation issues, policies and activities in order to integrate citizens' interests and values and to increase the quality, relevance, social acceptability and sustainability of research and innovation outcomes in various fields of activity from social innovation to areas such as biotechnology and nanotechnology
Action type: Coordination and support actions
Countries involved: Austria,Italy,Italy,Belgium,Finland,Romania,Norway,Poland,Bulgaria,Greece,Bulgaria,France,Denmark,Denmark
Call: Supporting the development of territorial Responsible Research and Innovation (H2020-SwafS-2018-1, 2018)
Start date: 2019-02-01
End date: 2022-02-28
Duration (months): 37.0
Total project cost (EUR): 1999833.75
EU funding (EUR): 1999833.75
Participants: 17
Project status: CLOSED

The TeRRItoria vision is to tackle a double challenge: to bring RRI at the forefront of the debate for developing local an regional R&I capacities; and to use RRI as a springboard for broadening the number of stakeholders involved in the process for enhancing the regional research and innovation strategies under the framework of S3. The overall objective of the project is to experiment with the adoption of Responsible Research and Innovation (RRI) approach in European regional and territorial R&I systems. TeRRItoria is based on the idea that RRI approaches, policies and practices, developed so far at the level of research institutions, may be adapted to that of regional and territorial governance. Thus the project will contribute to developing what can be called “Territorial RRI” by developing a set of transformative experiments in 5 European selected territories – 4 regions and 1 municipality (ReThe project’s vision is to tackle a double challenge: To bring RRI at the forefront of the debate for developing local and regional R&I capacities and to address the limits and barriers of the process for developing regional innovation strategies with a particular emphasis on S3, using RRI as a springboard for public engagement, social innovation, openness to diversity and curiosity. This will be done by developing a set of Transformative Experiments in 5 European selected territories - 4 regions and 1 municipality. The key objectives are: to introduce concrete and measurable changes in the R&I systems of the 5 above mentioned territories, so as to make them more inclusive; to introduce concrete and measurable institutional changes in the territorial organisations involved in the project, so that RRI becomes an embedded element of their planning process; to develop a better understanding of how RRI can be adapted at the territorial level and finally to contribute to the enhancement of the Smart Specialisation Strategy process through exploring synergies with RRI.

Keywords: open and inclusive territorial randi systems,transformative territorial experiments,quadruple helix,open science,open innovation,institutional change,territorial rri,governance innovation
Hydrophobic Ionic Liquid Technologies (HyLITE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-01-18
End date: 2018-01-17
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

HyLITE (Hydrophobic Ionic Liquid Technologies) aims to enhance established European strength and capability in the research and development of ionic liquid materials by targeting to production of new ionic liquids with specific, tailored, properties that are technologically functional and environmentally acceptable and can be manufactured from sustainable resources. Optimised atom efficient synthesis will produce new hydrophobic ionic liquids that contain only carbon, nitrogen and hydrogen atoms and so have low environmental impact and can be used as non-polluting extraction solvents in liquid/liquid separations springboarding sustainable innovation within industry and academia.

Keywords: liquid liquid separations,sustainable synthesis
High Performance Cold End Coating for Glass (ALGLASS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: France
Call: Accelerating the uptake of nanotechnologies, advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2015, 2015)
Start date: 2016-02-01
End date: 2016-05-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

ALGLASS project involves the industrialization of an advanced coating material that will improve the performance of glass containers during the industrial packaging, labelling and transport operations without increasing the price. Friction between bottles is unavoidable during the unpacking, cleaning, filling, closing, labeling and transport operations. Defects in the glass are generated and scratches appear, leading to low quality products. Glass manufacturers demand coatings that can also lubricate the ware so that it can be moved with high-speed handling equipment while being invisible in order to keep the high quality sensation of the glass. Currently, there are no products in the market completely fulfilling these requirements. We have developed a formulation that meets the specifications of glass manufacturers in terms of surface tension, burst resistance, scratch resistance and drying temperature, while being environmentally friendly (water-borne formulation) and safe for being in contact with food (according to the EU regulation 10/2011). The aim of ALGLASS project is industrializing our new coating for glass and during Phase 1 execution we will assess its feasibility, develop a business plan and perform a complete freedom to operate analysis to ensure no intellectual property issues hinder ALGLASS industrialization. The industrialization of this product will enable ALCEA FRANCE to penetrate in the European glass manufacturing market. We will develop a marketing strategy with a first stage focused in the main glass manufacturing countries: France, Italy and Germany, and aiming reaching the 28 European countries in a second step. We have already invested € 0.2 million in the development of the prototype, and estimate that an additional € 1.4 million budget will be required for successfully industrializing ALGLASS. The Return of Investment (ROI) of the project is 2.64, indicating that in 5 years we will earn 264% of the money invested.

Keywords: coating,glass,cold end,scratch resistance,transparency
Smart logistics for WASTE and recycling operations in European cities (SmartWASTE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Finland,United Kingdom
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-06-01
End date: 2019-05-31
Duration (months): 36.0
Total project cost (EUR): 2100449.56
EU funding (EUR): 1470314.7
Participants: 2
Project status: CLOSED

The key problem in waste collection today is static routes and schedules: truck drivers are driving “blindly” from bin to bin and collecting containers that are either half empty or over filled. This adds up to a large amount of unnecessary costs, such as time spent, gas consumption and greenhouse gas emissions. Globally, over 400 million waste containers are being served by millions of trucks every day, and 50 % of the value in the market is in the logistics. Enevo is a growing Finnish technology company that aims to capitalise on this 12-billion-euro business opportunity and become the #1 supply chain platform company for waste and recycling operations worldwide. As waste management plays a central role in the circular economy, Enevo is a key player in developing more efficient waste collection and management systems. Enevo helps its customers make their waste and recycling operations more efficient, leading to a more sustainable world. Enevo’s vision is to turn all waste in the world into a valued resource. SmartWASTE project is addressing two significant EU-wide challenges: 1) optimising transport operations and tackling the environmental and logistical challenges that the European transport sector is facing 2) waste management in the circular economy context. The objective of SmartWASTE proposal is to scale-up and expand the service into new European regions by piloting the solution with potential customers in 10 large scale pilots. Through piloting, Enevo gains important feedback that is provided back to product development to improve Enevo's offering and operations to be better suited for large scale regional expansion. The proposal’s activities aim at creating a solid foundation for Enevo’s successful business in European market and accelerate its expansion globally. Enevo is targeting, by 2021, to generate a revenue of 916 M€ and employ 1 500 people globally of which 1 000 will be in Europe.

Keywords: waste management,waste collection,smart logistics,recycling,route planning,routing,fill level monitoring,fleet optimization
Innovative banking model for improved financial and economic inclusion of population groups that find it difficult to open a traditional bank account (MONESE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: SME instrument
Countries involved: United Kingdom
Call: New business models for inclusive, innovative and reflective societies (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-05-01
End date: 2018-01-31
Duration (months): 21.0
Total project cost (EUR): 1607500.0
EU funding (EUR): 1125250.0
Participants: 1
Project status: CLOSED

Owning a bank account has become a precondition for participating in the economic and social life of a modern society. In the EU several population groups face remarkable difficulties in accessing a bank account service: 3.5 million mobile EU residents have had bank account access issues in their target countries and 22 million consumers would like an account but have not attempted to open one. Underlying causes include practices that place non-residents at disadvantage, irregular income, inadequate documentation, and cost and slowness of opening and owning a bank account. It is estimated that the annual opportunity cost of not having a bank account is €185-365 per consumer. Monese has launched a prototype of a mobile-first banking service that validates customer’s identity fully online, enabling access to banking even for customers with poor credit history or no formal proof of address. Account opening takes place in real-time, enabling 3-3000x faster onboarding (3 minutes). Monese aims to provide local bank accounts across European Economic Area for a transparent low-cost fixed-fee pricing (4x less expensive). The service is currently launched only in UK and has attracted >6000 customers, with 60 000 people waiting to get access. MONESE project aims to scale up the technical capability of the service for reaching and being able to serve growing number of users – to increase the level of automation of user identification, scale up service architecture and introduce features required for EU-wide reach. Combining these innovations with business model innovation (fixed-fee pricing, streamlined value proposition, value chain deconstruction, focus on underserved people) enables to achieve EU-wide scale in a profitable manner. Improving the access to bank account services is becoming a primary policy objective, pushing the drive for new products and business models. Development of the service to an EU-wide scale would increase Monese’s revenues by €97 million in 2020.

Keywords: financial inclusion,banking,payment accounts
Understanding and improving the sustainability of agro-ecological farming systems in the EU (UNISECO)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Research and Innovation actions
Countries involved: Austria,Spain,Italy,Germany,Belgium,Romania,Greece,Sweden,Switzerland,Finland,Lithuania,Hungary,Latvia,France,Czechia,Czechia,United Kingdom,United Kingdom
Call: Socio-eco-economics – socio-economics in ecological approaches (H2020-SFS-2017-2, 2017)
Start date: 2018-05-01
End date: 2021-04-30
Duration (months): 36.0
Total project cost (EUR): 4924771.0
EU funding (EUR): 4924771.0
Participants: 18
Project status: CLOSED

The overarching objective of UNISECO is to strengthen the sustainability of EU farming systems, through co-constructing practice-validated strategies and incentives for the promotion of improved agro-ecological approaches. We will enhance the understanding of socio-economic and policy drivers and barriers for further development and implementation of agro-ecological approaches in EU farming systems to identify and facilitate more effective management strategies for European agriculture. This requires a wider systems perspective, considering socio-economic, ecological and political settings at a territorial level. We will operationalise a socio-ecological systems framework that integrates external settings into a sustainability assessment of farming systems, paying particular attention to the role of different types of actors and their roles in sub-systems. UNISECO will provide a methodological toolkit to assess the environmental, economic and social impacts of innovative strategies and incentives for agro-ecological approaches in EU farming systems at farm and territorial levels. The methodological toolkit will be tested in participatory case studies in 15 European countries with different biophysical, socio-economic and socio-cultural contexts of farming systems. UNISECO is committed to a genuine transdisciplinary process, reflected in consortium composition of stakeholder and scientific partners, and the emphasis on multi-actor engagement. Group learning processes, integrating practical and theoretical knowledge, will benefit scientists, stakeholders and end-users through improved understanding on how to strengthen sustainability of EU farming systems. UNISECO addresses the work programme topic SFS-29-2017 and contributes to Sustainable Food Security by identifying and supporting farming systems that enable the production of healthy food while preserving the environment and bringing added value to farm households and the different stakeholders of the value chain.

Keywords: socio ecological systems,farm level assessments,territorial assessments,environmental policies,governance and policy analysis