Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Plasmon-mediated On-Surface Synthesis (PlasmOSS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: TERMINATED

Photochemistry on solid surfaces is a promising candidate for overcoming the current limitations of on-surface synthesis (OSS), including the constraints of metallic substrates, poor spatiotemporal control, and demand for high temperatures. However, this nascent approach has evidenced to date relatively modest efficiencies compared to thermally induced reactions. Concomitantly, the field of plasmon-mediated chemical reactions (PMCRs) has experienced pronounced growth. PMCRs rely on the ability of plasmonic nanostructures to harness the advantages of milder visible light and efficiently transforming it into chemical energy. The rapid progress in PMCRs can be attributed to the development of novel methodologies for engineering the nano-optical properties of the localized surface plasmon resonance (LSPR). In this context, achieving precise atomic-level control over how reactants interact with plasmonic catalytic substrates holds the potential to drastically increase the chemoselectivity, efficacy and sustainability of reactions. The scientific objective of this proposal is to combine my expertise on scanning probe microscopy (SPM) and plasmonic nanocavities with the large experience of the host in OSS, targeting to direct PMCRs on surfaces at the atomic scale. Specifically, this proposal seeks to investigate three model photodimerization reactions, exploring the conditions under which the SPM-controlled optical hotspot -used for tip-enhanced Raman spectromicroscopy- can be transformed into a chemical hotspot with improved selectivity and efficiency. Furthermore, the goal is to elucidate the mechanisms governing tip-induced PMCRs, with the ultimate aim of controlling the fabrication of low-dimensional extended polymers with molecular precision using visible light. The synergistic integration of these innovative methodologies will decisively contribute to the successful realization of the project, remarkably enhancing my career trajectory and personal development.

Keywords: scanning probe microscopy,tip enhanced raman scattering,plasmonics,on surface synthesis
LARGE-SCALE MAGNETIC COOLING (LEMON)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Germany
Call: EIC Pathfinder Challenge: Clean and efficient cooling (HORIZON-EIC-2023-PATHFINDERCHALLENGES-01, 2023)
Start date: 2024-09-01
End date: 2027-08-31
Duration (months): 36.0
Total project cost (EUR): 3968750.0
EU funding (EUR): 3968750.0
Participants: 1
Project status: SIGNED

The objective of the LEMON project is the development and technical demonstration of a process for the scalable, permanent, helium-3-free generation of very low (cryogenic) milli-Kelvin temperatures based on continuous Adiabatic Demagnetization Refrigeration (cADR). It is aimed at providing the technical basis for large-scale refrigeration systems with, in principle, arbitrarily high cooling capacities at cryogenic temperatures, by connecting the same basic cooling unit together many times. The proposed novel approach to large-scale cryogenic cooling promises to meet for the first time the growing and diverse cooling requirements in the field of quantum technologies, especially in the field of quantum computing (QC). It will make the high cooling powers required for QC (in the range of some hundred µW to several ten mW) available for the first time ever, thereby lifting the disruptive and ultimately economic potential of QC. In addition, the dependence on the critical resource helium-3, which is only available to a very limited extent in the EU and so far cannot be substituted, will be resolved; Overall, a decisive contribution can be made to the technological sovereignty, competitiveness and technological leadership of the EU in the field of applied quantum technologies.

Keywords: magnetocaloric cooling,adr,quantum technologies,critical supply chains
Next Generation of edge AI crossing technology fields (NeAIxt)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: France,Czechia,Germany,Sweden,Finland,Denmark,Greece,Spain,Netherlands,Italy,Portugal,Israel,Türkiye,Switzerland
Call: Topic 1 Global call according to SRIA 2024 (HORIZON-JU-Chips-2024-1-IA, 2024)
Start date: 2025-09-01
End date: 2028-08-31
Duration (months): 36.0
Total project cost (EUR): 95628952.84
EU funding (EUR): 25010735.0
Participants: 67
Project status: SIGNED

Europe is poised to play a pivotal role in the technological revolution, particularly in the field of edge AI, which promises sustainable growth, performance, and reliability. The NeAIxt project is a strategic initiative designed to foster European independence and control over edge AI technology, benefiting both companies and citizens. The project presents a golden opportunity for European SMEs to grow, network, and enhance skills, leveraging exposure to the global market. Research labs and RTOs will bridge the gap to the future by developing necessary technologies and competencies, while universities will cultivate and disseminate advanced skills required for this technological evolution. NeAIxt aims to solidify Europe's position in edge AI and eNVM technology by enhancing AI enablers, evolving eNVM for edge applications, and demonstrating AI capabilities at both chip and system levels. The project is committed to ensuring the safety and security of AI services, adhering to EU regulations. Key technical developments include the advancement of 18nm FD-SOI and next-generation embedded Phase Change Memory (ePCM). These innovations will lead to high-performance, secure microcontrollers with AI capabilities, offering low power consumption and high security for smart applications. The project will integrate advances in non-volatile memory technologies with cutting-edge MCU design to enable efficient in-memory computing. This synergy will deliver a fully European solution for reliable, safe, and independent edge AI applications. NeAIxt will address the entire edge AI value chain, from academia to industry, and from design to end-user applications, building on Europe's strong technological foundation. The project's outcomes will alleviate societal concerns about AI proliferation by ensuring compliance with European privacy standards, fostering AI adoption in various sectors.

Keywords: edge ai,envm,ai,use cases,demonstrators
AI and Robotics for Prostate Biopsy (ROBIOPSY)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Italy,Austria,Germany
Call: EIC Transition Open 2022 (HORIZON-EIC-2022-TRANSITION-01, 2022)
Start date: 2023-05-01
End date: 2026-04-30
Duration (months): 36.0
Total project cost (EUR): 2499141.25
EU funding (EUR): 2499141.0
Participants: 5
Project status: SIGNED

The ROBIOPSY project aims at evolving the robotic device for prostate cancer (PC) biopsy demonstrated during the ERC-PoC PROST into a product prototype that will be ready for clinical trials. The focus of the project will be two-fold: the engineerization of the PROST prototype, and the accurate analysis of the business case of prostate cancer diagnosis and its potential extension to focal therapy. We will correct the shortcomings of the pre-clinical tests, meet the strict medical certification regulations, and address the Health Economics implications of our solution. ROBIOPSY will achieve better performance than current competitors because it solves the two main causes of PC diagnostic error: uncertain target identification, and inaccurate needle positioning, as demonstrated in the pre-clinical tests. A novel image fusion method will permit to significantly reduce the target uncertainty, while the robotic device will zero the positioning error.The ROBIOPSY prototype will consist of a single cart holding the robotic needle positioner, and housing all the electronic components. The electronics will be divided into two subsystems: interface and data processing, and safety critical controls. This will reduce the operational risks and will simplify the medical certification. A multi-centric study is ongoing to collect biopsy images to train the Machine Learning algorithms for prostate segmentation and lesion identification. In parallel to the technical development, we will analyze in depth the business case of prostate biopsy in selected European Countries, we will analyze the time/cost reduction due to the new device and will establish the economic foundation of focal therapy, to be ready for the expected evolution of PC treatments.

Keywords: robotics for healthcare,ai powered image processing,robotic biopsy,certification verification validation
Building PREPAREDness with Collaborative Knowledge Platform, Gamification and Serious Game in Virtual Reality (B-prepared)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Disaster-Resilient Society for Europe
Action type: Innovation actions
Countries involved: Hungary,Germany,Norway,Sweden,Italy,Ireland,Luxembourg,Poland,France,Israel,Austria
Call: Enhanced citizen preparedness in the event of a disaster or crisis-related emergency (HORIZON-CL3-2022-DRS-01, 2022)
Start date: 2023-10-01
End date: 2026-09-30
Duration (months): 36.0
Total project cost (EUR): 5566925.0
EU funding (EUR): 4998765.0
Participants: 16
Project status: SIGNED

Recent disaster events, like the 2021 flood in Germany showed clearly, that even the best alert systems and top first responder organisations can not prevent fatalities and serious damage on property without having prepared the citizens how to act and react during disaster situations and crises, understand alerts and follow instructions. B-Prepared offers a cost-effective solution for building a culture of disaster preparedness with a multi-actor approach in realistic historical scenarios. B-prepared builds on a freely accessible massive collaborative knowledge base and data hub, demonstrating its usefulness via three demonstrator applications: a cooperative multiplayer VR serious game, simulating real disaster scenarios for the safest near-real experience; an interactive gamified mobile app with age-appropriate content and enhanced accessibility to people with specific functional needs for the widest possible reach; and an LMS system to effectively and comparably measure preparedness levels achieved by VR and/or mobile users on a unified scale. Players can take different roles to solve puzzle tasks in an immersive experience. Teamplay, collaboration and communication are keys to survival, strengthening the culture of mutual assistance and cooperation in danger. Player behaviour and gameplay logged in a privacy-preserving way helps collect data on in-game behaviour which serves assessment of preparedness but will also be shared with other synergic research in the same field. A large-scale virtual reality hackathon series will demonstrate its features. The open beta will be publicly available as a giveaway, inviting stakeholders via direct outreach. After closing beta, the game will be available in a non-profit freemium model where in-game purchases are replaced by in-game donations for relief organizations, with a small percentage kept for maintenance and further development.

Keywords: virtual reality gamification,learning management system,serious games,gamified mobile application,game based learning,collaborative platform,environment modelling,disaster knowledge base
Using Plasmodium vivax genetic data to estimate the cause of recurrent vivax malaria (PvRecur)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-11-07
End date: 2025-11-06
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

Malaria infects hundreds of millions of people year on year. The WHO is committed to a world ultimately free of malaria. Of the two most important causes of malaria, Plasmodium vivax is the most difficult to eliminate largely because it has the capacity to relapse: causing recurrent malaria via the activation of latent liver-stage parasites. Recurrent malaria can also be caused by the failure to treat a previous blood-stage infection (recrudescence) and, in endemic settings, new infectious mosquito bites (reinfection). Knowing the cause of recurrent malaria is key to understanding malaria epidemiology and to providing efficacious treatment. For example, to evaluate the efficacy of a drug designed to kill P. vivax liver-stage parasites in an endemic setting, reinfections and recrudescence must be separated from relapses. However, there are no direct ways to diagnose the cause of recurrent malaria. To address this problem, I aim to build a tool (Pv3R) that uses Plasmodium vivax genetic data to estimate the probability of Relapse, Recrudescence and Reinfection, and use Pv3R to estimate the burden of relapse and its contribution to transmission, thereby validating Pv3R’s utility. I will achieve my objectives by merging my existing expertise in statistical malaria genetics with the expertise of Dr Michael White and his lab, its ties with field-based P. vivax epidemiology and its capacity to generate P. vivax genetic data. Working with Dr White, I will develop a state-of-the-art statistical inference method to tackle the challenging unsolved problem of differentiating between the causes of recurrent P. vivax. This will generate knowledge that directly improves our understanding of P. vivax epidemiology and, most long-lastingly, a public health resource (Pv3R) that can be used sustainably by the malaria community to generate more epidemiological knowledge and to guide the design of more effective treatment regimens needed for P. vivax control and elimination.

Keywords: malaria,plasmodium vivax,statistical genetics,bayesian modelling,markov chain monte carlo mcmc
Molecular Magnetism Expansion Toolkit for Instrumentation and Characterization: External Stimuli on Electronic Energy Levels in Magnetic Systems (MAGNETIC-ESTEEM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 1
Project status: SIGNED

Innovation in scientific instrumentation is essential for advancing technology and pushing the boundaries of scientific knowledge. Cutting-edge tools enable researchers to explore previously inaccessible physical phenomena, leading to breakthroughs in new materials and processes. One promising application is the use of lanthanide single-molecule magnets (SMMs) in quantum information science, due to their magnetic bistability, which can be controlled by external stimuli. The design and control of magnetic properties in molecular magnets—and their practical applications—depend on the understanding and manipulation of the energy levels that define their electronic structure. To further the development of future quantum technologies, it is critical to understand how external stimuli, such as light and pressure, influence the electronic states of SMMs. This project aims to develop two innovative scientific probes to investigate the effects of light (via magneto-chiral luminescence) and high pressure on the electronic energy levels of chiral lanthanide-based single-molecule magnets. By expanding the toolbox of techniques available to chemists and physicists working in molecular magnetism, this research will address current limitations in both instrumentation and theoretical understanding. Ultimately, this work seeks to bridge these gaps, with potential applications extending to the field of quantum information science for optical data-readout mechanisms.

Keywords: single molecule magnetism molecular magnetism chirality dichroism luminescence light matter chemical physics lanthanides pressure instrumentation design
Geometry and Topology of Singularities (GTSP)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-09-01
End date: 2025-10-31
Duration (months): 26.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 2
Project status: SIGNED

This interdisciplinary project brings together innovative ideas and techniques from algebraic geometry and complex analytic geometry, singularity theory, commutative algebra and topology. Given two complex analytic varieties X and X' that are part of an analytic family in a complex affine space we will study the relationships between the different similarities X and X' might share. Such similarities can be of geometric and topological nature.The synonym for similarity we will use here is equisingularity. We say X and X' are topologically equisingular if there is a homeomorphism between X and X' that extends to an ambient homomorphism that trivializes the entire family; we say that X and X' are geometrically equisingular if X and X' have similar resolution of singularities, or if a resolution of the entire family induces a resolution of each fiber. Understanding the topology of either X or X' usually involves a continuous deformation of either one of them to a smooth variety, the existence of which is guaranteed under a special smoothability hypothesis. A stronger version of topological equisingularity, called Lipschitz equisingularity, asks for a homeomorphism between X and X' that satisfies the Lipschitz inequality. The ultimate goal of the project is to gain insight in the relationships between topological (Lipschitz) and geometric equisingularity and develop an approach to study the topology of singularities that are not necessarily smoothable without imposing special dimension (or codimension) assumptions as was done previously.

Keywords: singularities,equisingularity theory,resolution of singularities,multiplicities,integral closure,lipschitz geometry
Roaming Ancestry – Landscapes of social and genetic relations in prehistory (ROAMANCE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 2496811.0
EU funding (EUR): 2496811.0
Participants: 1
Project status: SIGNED

Kinship systems and networks of contact and exchange in prehistoric societies could so far only be studied indirectly. Recent advances in archaeogenetics have enabled the retrieval of ancient genomic data with high success rates, which often allows the study of nearly all individuals from the same archaeological site, making intra-site studies become reality. Estimating degrees of biological relatedness and demonstrating biological unrelatedness can form a robust scaffold to reconstruct social and kin relations, which permit stable inferences on kinship structures and social organisation in prehistoric societies. Further analytical advances that estimate shared identity-by-descent between individuals can identify biological relatives up to the 10th degree, which has enabled the detection of distant relatives between different sites. Many such connections across sites and regions can be found in the published ancient human genomes from Europe’s prehistory, and the chances to find more scales up quadratically with the number of individuals studied. Through full integration of archaeological, anthropological, isotopic and other context data, it will for the first time be possible to match levels of resolution in archaeology and genetics, to map relationships over geographic distances, and to learn how prehistoric communities were organised, interacted and formed networks. Given these exciting prospects, this project will enhance the data density in Neolithic and Bronze Age Europe by including new well-contextualised sites and regions at our disposal with the aim to build comprehensive maps of contact, trade and exchange based on quantifiable and statistically robust measures. This unique, large-scale, spatio-temporal reference dataset will allow us to use innovative integrated modelling approaches that explore theoretical frameworks and kinship models from ethnographic studies, and to produce novel insights into the evolution and structures of human societies.

Keywords: ancient human dna,migration,mobility,biological relatedness,kinship,social organisation,prehistory