Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Soft intelligence epidermal communication platform (SINTEC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Spain,Italy,Sweden,Sweden,Sweden,Netherlands
Call: Flexible and Wearable Electronics (H2020-ICT-2018-2, 2018)
Start date: 2019-01-01
End date: 2023-06-30
Duration (months): 54.0
Total project cost (EUR): 3999262.5
EU funding (EUR): 3999262.5
Participants: 9
Project status: SIGNED

Electronics are set to merge with our bodies to extend our perceptions. Smartphones and watches will give way to the bodyNET: a network of sensors and smart devices woven into our clothing, worn on our skin and implanted in our bodies. Smart wearables are the next step in the Internet of Things wearable evolution. This market is one of the most vigorous over the coming years. SINTEC addresses a market, in terms of size, that reach over €70BN by 2026. A large amount of scientific results have emerged and a few start-ups are focused on stretchable electronics and sensors that employ liquid alloys for interconnects and passive components. However, there are until today no dedicated commercial equipment for manufacturing of such devices. This hinders large-scale industrial exploration and needs to be addressed. By a novel manufacturing technology for large area rigid-stretch PCB and integration, SINTEC will provide soft, sticky and stretchable sensor patches that can be used multiple times and at longer periods. With its dynamic compliance and water repellent permeable encapsulation it withstands vigorous action, sweating and water; making it ideal for an active life. A ground breaking intra body communication technique gives large bandwidth and secure consumption at low power, allowing for multiplex sensoric inputs from many nodes on the body. To demonstrate the advantages of the novel technology, SINTEC will apply it in clinical environment and in athletics performance evaluation. Industrial partners will exploit the results in manufacturing technology, Fat-IBC, and in soft compliant smart patch applications, e.g., in preventive care, sports and fitness, and medical technology.

Keywords: stretchable electronics,skin electronics,fat channel,intra body communication,stretchable pcb,rigid stretch,smart patches,electrophysiology,sports,clinical,healthcare
Anal Fistula Treatment (BioHealx)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Ireland
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2019-01-01
End date: 2022-06-30
Duration (months): 42.0
Total project cost (EUR): 3319161.25
EU funding (EUR): 2323412.0
Participants: 1
Project status: CLOSED

Signum Surgical Ltd. is a medical device company developing a solution to anal fistula disease. Anal fistulas are a common rectal disease affecting 2 out of every 10,000 people globally. An anal fistula is an artificial tunnel that, in the majority of cases, develops from an infection that begins within a blocked anal gland. If the infection cannot be cleared from the anal gland an abscess forms and the infection burrows though muscles in the rectum and exits externally at the buttocks. Patients endure a poor quality of life, experiencing pain associated with the tract and related abscesses and suffering faecal, pus and blood discharge from the fistula tract. Many patients must wear pads to control leakage, and those who seek treatment face poor surgical outcomes. There is currently no gold standard treatment for anal fistula treatment, which has not changed significantly in over 2,500 years when Hippocrates described using horse hair and silk to drain the fistula tracts. Surgeons are frustrated with the commercially available treatment options which either result in inadequate healing of the initial condition, introduce incontinence as a consequence of surgical treatment, or result in repeat procedures and additional cost to health care system. Through close collaboration with expert colorectal surgeons, Signum Surgical has developed the BioHealx device - an intuitive novel single use technology which improves upon current state of the art devices and surgical procedures to meet all identified critical clinical requirements to reliably heal anal fistulas. During this H2020 project, the company seek to demonstrate the technology in man to enable product launch and growth of sales in the U.S. and Europe.

Keywords: anal fistula disease
Alone against Secularisation? Gender identity in Anglican and Catholic women (England-Spain, 1960-2015) (Gender identity)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-09-01
End date: 2021-12-07
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

This project’s overall objective is to carry out a comparative study of the construction of the self of both Anglican and Catholic women during the last five decades. Following a gender perspective, it will analyse how women belonging to these Churches have reacted to the recent transformations experienced by the English and Spanish societies. Particularly, this project will focus on two of these changes. Firstly, the accelerated secularisation of both societies, a process which started in the late eighteenth century and was consolidated during the cultural revolution of the 1960s. Since that point established Churches, like Anglicanism in England and Catholicism in Spain, lost on a great part of their former social support and cultural influence. The second aspect will be the emergence of second-wave feminism during the 1960s, which broadened the feminist agenda to a wide range of issues, like sexuality, family and reproductive rights. By relying on oral history methods, especially useful to analyse the complex process of identity construction, this research project wants to know how these women dealt with those social and cultural transformations in order to shape a particular gendered and religious identity. Three main questions will be addressed by this project: How has the different evolution of Catholicism and Anglicanism from 1960s onwards affected female believers? Did the historical link between women and religion disappear at the end of the 20th century? How have interviewees managed to reformulate the role of religion in their lives before the secularist and feminist claims? The main deliverables will be two papers published in leading international journals and a book published either in English or Spanish. The fellowship will be highly beneficial to establish the researcher as one of the main European experts on the history of secularisation from a gender point of view.

Keywords: gender,identity,oral history,secularisation,anglicanism,catholicism
Astronomical Solutions over Geological Time (AstroGeo)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: France
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2020-11-01
End date: 2026-10-31
Duration (months): 72.0
Total project cost (EUR): 2498956.0
EU funding (EUR): 2498956.0
Participants: 2
Project status: SIGNED

According to Milankovitch (1941), some of the large climatic changes of the past originate in the variations of the Earth’s orbit and of its spin axis resulting from the gravitational pull of the planets and the Moon. These variations can be traced over several millions of years (Ma) in the geological sedimentary records. Over the last three decades, the Earth’s orbital and spin solutions elaborated by the PI and his group (Laskar et al, 1993, 2004, 2011) have been used to establish a geological timescale based on the astronomical solution (e.g. Lourens et al, 2004; Hilgen et al, 2012). Nevertheless, extending this procedure through the Mesozoic Era (66-252 Ma) and beyond is difficult, as the solar system motion is chaotic (Laskar, 1989, 1990). It will thus not be possible to retrieve the precise orbital motion of the planets beyond 60 Ma from their present state (Laskar et al, 2011). The PI's astronomical solutions have been used by geologists to establish local or global time scales. AstroGeo is designed to achieve the opposite. We will use the geological record as an input to break the horizon of predictability of 60Ma resulting from the chaotic motion of the planets. This will be done in a quantitative manner, and aims to provide a template orbital solution for the Earth that could be used for paleoclimate studies over any geological time. This project stems from the achievement of Olsen et al (2019) where for the first time, in a study that involves the PI, it was possible to precisely recover the frequencies of the precessing motion of the inner planets. AstroGeo will not provide a single or a few solutions, but a whole database of solutions that would equally fit all available astronomical observations. This will open a new era where the geological records will be used to retrieve the orbital evolution of the solar system. It will thus open a new observational window for retrieving not only the history of the Earth, but of the entire solar system.

Keywords: milankovitch cycles celestial mechanics,chaos,solar system evolution,earth moon system evolution
Parenthood and Parental Desires among LGBTQ People: Generational and Cross-national Perspectives (LGBTQ Parenthood)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France,United States
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-05-01
End date: 2024-04-30
Duration (months): 36.0
Total project cost (EUR): 257619.84
EU funding (EUR): 257619.84
Participants: 2
Project status: SIGNED

LGBT rights and non-discrimination policies towards gender and sexual orientation are at the top of the European Union’s priorities. Over the last decades, Western countries greatly improved the legal recognition of LGBTQ families, while an increasingly part of them are allowing same-sex couples to marry and to access adoption process and/or artificial reproductive technologies (ART). In France, same-sex couples can adopt children since their legal possibility to marry in 2013, but as there are very few minor children to adopt through the accredited adoption agencies, most of them try to develop other possibilities by conceiving their own biological children. The dramatic changes in the legal contexts simultaneously imply a generational shift in the routes to parenthood among LGBTQ people. However, the legal restriction preventing single women and women couples to access ART and the prohibition of surrogacy in France compel same-sex couples to engage "procreative migrations" in other countries, which carry economic inequalities. People who face strong barriers to achieve their parental desires thus may be lest satisfied with their life, face higher risks of depression and feel less support within their families of origin. Therefore, while most research focused on well-being among children raised by same-sex couples, access to parenthood also raises mental health issues among LGBTQ adults. Cross-national insights between France and US, using mixed methods in the two countries, will then highlight policy effects in the family lives of gender and sexual minorities, and thus challenge policy makers. The analysis of LGBTQ parenthood across generations will also contributing to enlighten social change. Consequently, the research project will lead to better understanding of LGBTQ families and the challenge they face, but also to initiating scientific discussions in France concerning their inclusion in surveys and research works.

Keywords: sexuality,family,parenthood,procreative rights,gender and sexual minorities
tle Easy identification of optimal translators in a global digital marketplace (VAL)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Denmark
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-09-01
End date: 2020-02-29
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The Language Service Providers (LSP) in the translation industry currently relies heavily on freelance translators, but despite a high global demand for text translation services, it appears increasingly difficult to find adequately qualified translators for the job. Additionally, LSPs are subject to an increasing pressure to deliver higher quality translations while cutting down on costs and time. Despite improvements on automated translations via software, human translators are necessary to provide quality work. In an attempt to bridge that gap, EasyTranslate has developed VAL, a self-learning platform which will analyse and classify the text by keywords and match the task to the most qualified translator for that particular job. The platform will then analyse the translated text to improve its understanding of the translation made and provide a better match in the future. VAL links the customer seamlessly to the translator and makes an instantaneous best value offer thanks to a dynamic pricing algorithm. The customer therefore enjoys a faster process of higher quality with a better transparency on the VAL platform. EasyTranslate already evolves in the large global translation market, including most of its activity in the European Union, with many large customers including the Danish state and private corporations. The EU has shown a steady interest in efficient translation services and will continue on supporting the demand in the years to come with constant growth. As a cloud-based SAAS product, VAL will be accessible online to any individual, organisation or corporation that requires translation services. It will initially focus on translations between English and French, German or Chinese, and will be extended to its large customer database overtime. The phase 1 project validates the feasibility of VAL as a project for the market. The concept will be confirmed commercially, financially and technically, to ensure due diligence of the business plan viability.

Keywords: translations,languages
HYPHEN: Hybrid Photonic Engines for Massive Cloud Connectivity (HYPHEN)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2015-08-01
End date: 2017-01-31
Duration (months): 18.0
Total project cost (EUR): 149875.0
EU funding (EUR): 149875.0
Participants: 1
Project status: CLOSED

The global explosion of data traffic and the migration of essential services to “the cloud” are combining to push current data-center infrastructures to their limits. This applies in particular to communication networks within and between data centers (DC), which limit scalability of computing and storage already today. Wavelength-division multiplexing (WDM) transmission schemes are key to overcome these bottlenecks, increasing the throughput of inter-DC and intra-DC communication links by more than an order of magnitude. However, but there are currently no WDM systems in the market that fulfill the associated cost and performance requirements: Conventional systems based on discrete components such as SFP+ or CFP transceivers are far too bulky and too expensive, while monolithic photonic integration remains technologically challenging and constrained in performance. The fundamental question remains: How to flexibly combine photonic components of a variety of material systems to create cost- and performance-optimized solutions for data centers? The answer to this question will unlock multi-billion-Euro market opportunities connected with cloud networks. HYPHEN aims at exploring and verifying the commercial potential of a novel class of optical WDM engines that combine the benefits of a large-scale photonic integration with the design flexibility of discrete systems. The optical engines are based on hybrid multi-chip integration and exploit the technique of photonic wire bonding, which was established and elaborated in the framework of the ERC Stating Grant EnTeraPIC. HYPHEN comprises an in-depth analysis of market opportunities and competitive boundary conditions, the specification of technical product concepts that are geared towards the most important technology gap, as well as the associated IP strategy and risk analysis. The project shall result in a comprehensive business plan that allows to raise funds for the next phase of commercialization.

Keywords: optical communications,photonic integration,hybrid integration,photonic wire bonding,wavelength division multiplexing,data center,optical interconnects,silicon photonics
EU market research for an innovative algae based tertiary wastewater treatment system (IPHYC-H2020)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Biotechnology
Action type: SME instrument
Countries involved: United Kingdom
Call: SME boosting biotechnology-based industrial processes driving competitiveness and sustainability (H2020-SMEINST-1-2014, 2014)
Start date: 2015-05-01
End date: 2015-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Industrial Phycology (I-PHYC) has developed a wastewater treatment (WWT) process that can meet increasingly stricter discharge consents for the concentration of nitrogen (N) and phosphorus (P) in wastewater (WW) effluents. Elevated levels of N & P are linked to detrimental environmental events e.g. eutrophication. WWT operators require a treatment process that is able to remove nutrients in an energy efficient manner which current technology cannot meet. I-PHYC’s novel patented treatment process uses microalgae (MA) to remove nutrients from WW effluents. MA reproduce rapidly when sufficient nutrients, light and CO2 are supplied. The MA consume the nutrients of the WW until exhausted producing a clean effluent that meets new EU consents and allows the operator to meet its statutory commitments while avoiding financial penalties. The biomass is retained for reactor seeding or harvested for valorisation e.g. anaerobic digestion of biomass to produce electricity. I-PHYC has estimated that valorisation will offer a payback period on CAPEX of 2.5-3 years, with significantly reduced OPEX. The process has been validated by I-PHYC in a recent field trial (late 2013) at Avonmouth WWT, UK. The field trial was based on a 1 m3 system which replicated all the functions of a commercial scale system. Results from the trial demonstrated a reduction in the tertiary treatment effluent concentration of P and ammonia by >70% and COD by>30%. Currently, I-PHYC is trialling a 20 m3 system onsite at a municipal WWT works with our strategic partner ‘Wessex Water’. I-PHYC is applying for funds to undertake a market study to determine the best approach for entering the EU market for P removal in WW effluent by: marketing the solution to the various firms in the EU operating under different local regulations; determining market size, growth trends and competition; and how to price its innovation. This funding will help I-PHYC to develop the strategy required to bridge the market adoption gap

Keywords: microalgae,tertiary wastewater treatment,phosphorus removal,secondary industrial wastewater,treatment
A Next-generation targeted immuno-oncology therapy (NEXIM)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In spite of enormous medical progress, aggressive forms of cancer remain one of the leading causes of death across the globe. Metastasized prostate, lung, breast and colon cancer account for a combined mortality of approximately 0,8 M lives in Europe per year. Immunotherapies, activating patient’s own immune system to target and destroy tumor cells, have shown enormous promise in the treatment of metastatic forms of cancer, creating a huge market with a €100B potential in 2022. However, these drugs are only effective in 15-25% of patients, and their use is associated with severe side effects. Therefore, there is an unmet medical need for next-generation of cancer immunotherapies with improved safety and consistent efficacy in a broader patient population. TargImmune, is a Switzerland based company with a mission to develop novel targeted immuno-oncology drugs that will improve the treatment of patients with aggressive tumors. Using our proprietary treatment technology based on the targeted intracellular delivery of an RNA-analogue inside the tumor, we will provide novel systemic immune therapy for metastasized cancer with less side effects and improved effectiveness across all patient populations. Currently we have 3 drugs in development for prostate, breast cancer and solid tumors. All potential pipeline candidates address a highly attractive immune-oncology market, with the total addressable market for our first asset of €1.7B. The product is predicted to generate €466M of cumulative annual revenues through 10 % royalties over sales in the first 5 years, as a part of licensing deal with a large pharmaceutical company. After initial investment round, we currently seek for additional funding to further develop our pipeline candidates. In the NEXIM project, we will finalize an investor-ready business plan, required to ensure additional investments. The project will also include an analysis of the competitor and investor landscape and market positioning.

Keywords: cancer immunotherapy,metastasized cancer,solid tumors,drug development,drug targeting and delivery,immune checkpoint inhibitors