Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Sustained Concerns: Administration of Mineral Resources in Central Europe, 1550-1850 (SCARCE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-11-01
End date: 2028-10-31
Duration (months): 60.0
Total project cost (EUR): 1403898.0
EU funding (EUR): 1403898.0
Participants: 1
Project status: SIGNED

Early modern mining often played out as a drama in three acts: I. Ores are Discovered, II. Communities Flourish, III. The Mines Collapse. Across Central Europe, however, this drama took an unusual turn: emerging territorial states stepped in to reorganise the sector and suspended the collapse of mining for years, decades, and centuries. Understanding why and how state-employed administrators prolonged the lifespan of mines has great potential to advance debates in economic history, history of science and technology, and environmental history. The principal aim of this project is to open up the history of resource management as a field of study whose questions and results are equally well integrated in these three fields. It will use Central European mining as a high-stakes case to prove the viability of such a history. By doing so, it will provide (1) a new account of capitalist development by showing how an industry in seemingly underdeveloped Central Europe shaped two important building blocks of modern economies: the rationalisation of labour, and the accumulation of capital. (2) a new understanding of technoscientific innovation in proto-industrial settings by showing how administrative procedures (accounting, reporting) shaped scientists/technicians’ understanding of natural processes. (3) a new genealogy for modern sustainability by focusing attention on the contradictions that shaped the extraction of non-renewable resources. To achieve these aims, four researchers (1 PI, 1 Postdoc, 2 PhD) will analyse thousands of administrative reports from across Central Europe, using a new method, history of bureaucratic knowledge, based on recent advances in the history of science. They will work on four processes through which administrators made mining a long-term enterprise: (a) rationalising labour, (b) managing health and pollution, (c) sustaining investment, and (d) long-term planning.

Keywords: environmental history,mining history
Higher-order electroweak corrections to the Standard Model effective field theory (HEW-SMEFT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 193643.28
EU funding (EUR): 193643.28
Participants: 1
Project status: SIGNED

The lack of conclusive experimental evidence for new physics (NP) underscores the need for a comprehensive strategy beyond the Standard Model (SM). Current experimental results suggest that NP could be heavy and, therefore, beyond the direct reach of current colliders. This possibility makes Effective Field Theories (EFTs) an invaluable tool for NP searches, allowing us to exhaustively exploit information from diverse measurements, observables, and experiments across different energy scales. One such EFT, widely used in the search for physics beyond the SM, is the Standard Model Effective Field Theory (SMEFT). The sensitivity to NP hinges on the accuracy of SMEFT predictions, as the effectiveness of SMEFT lies in establishing correlations among potential deviations in SM interactions. The more precise these predictions are, the greater the sensitivity to NP effects, leading to more stringent constraints from SMEFT global studies. Sudakov electroweak (EW) logarithms represent the leading higher-order perturbative EW corrections at high energies—a regime where EFT effects are expected to dominate. This project leverages this feature, aiming first to compute the one-loop Sudakov EW corrections for diboson production in SMEFT. The second goal is to perform a complete one-loop EW computation for vector boson pair production in SMEFT, capturing EW corrections beyond the logarithmic ones, given the process's critical importance for EFT studies. Given the current state of the art in both SM and SMEFT predictions, this project is poised to push the frontier of theoretical predictions for LHC studies. The project is structured into three work packages, encompassing the analytical calculations, their implementation into a flexible Monte Carlo framework, and the dissemination of results through peer-reviewed publications and presentations at international and local conferences.

Keywords: effective field theories,higher order calculations,electroweak theory,collider phenomenology
Genetic lethal interactions in replication licensing-defective cancer cells (ELLIPSIS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Greece,United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 197263.68
EU funding (EUR): 197263.68
Participants: 2
Project status: SIGNED

Genetic lethal interactions, which describe the lethal effect of combined perturbations in two or more genetic factors whilst individually have no effect, have emerged as a significant topic in the field of targeted cancer therapy. Despite their promising performance in clinic, current genetic lethality-based therapies focus mainly on digenic interactions restricting the size recipient patients. Complex genetic interactions that involve deregulation of innate mechanisms or cellular responses offer an alternative approach in the development of anti-cancer therapy. Impaired licensing of DNA replication represents a common feature of cancer cells fuelling genomic instability. Cancer cells manage to proliferate and expand under conditions of impaired licensing suggesting that have acquired special mechanisms that are not present in normal cells. Here, my aim is to unveil genetic interactions that induce lethality by investigating the mechanisms that enable the survival of licensing-defective cancer cells. Using colorectal cancer as a model, I will first identify the genes that are overexpressed in tumour cells that exhibit licensing defects. Secondly, I will interrogate the consequences of genes inactivation in the survival of cells by employing a CRISPR/Cas9 screen in a cell system of inducible licensing defects by the overexpression of the licensing factor Cdt1. Finally, the identified hits will be validated through functional experiments in cell systems and model organisms to establish their lethal effect. Our results will identify novel factors that upon inhibition induce the selective cell death of cancer cells and we anticipate that they will be attractive targets for future studies on drug design and development.

Keywords: replication licensing,cdt1,crispr cas9
Autonomous Sampling with Robotics in the Wild for Nature Conservation (WildBotics)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Denmark,United Kingdom,Portugal,Spain,Netherlands,Germany,Ireland,Kenya,Greenland,Sweden,Norway
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 4251284.43
EU funding (EUR): 3716986.68
Participants: 19
Project status: SIGNED

The need for effective, cost-efficient conservation practices is greater than ever as we are now facing catastrophic loss of Earth’s biodiversity. Current conservation practices, from sample collection to inspection and monitoring, are typically very labour intensive, costly and time-consuming. Collected data are often inaccurate, incomplete or subject to human bias. However, recent advances in robotics and Artificial Intelligence (AI) technologies have shown a great potential for offering practical tools for conservationists. Therefore, the aim of WildBotics is to boost ecosystem conservation practices through innovation in robotics, sensors and AI solutions. Autonomous terrestrial, aquatic, and aerial robots will be used as a unifying platform to elevate the ongoing digital revolution of nature conservation practices and integrate leading-edge conservation ecology and computer science. WildBotics will develop new autonomous long-endurance systems, improve current sensor and software capabilities and combine these advances to create practical solutions for large-scale automated monitoring or collection of samples, thus supporting cutting-edge conservation research. WildBotics will expand current computer vision capabilities in ecology, create practical solutions for monitoring wildlife populations and ecosystems, and offer effective and automated means of gathering and interpreting samples. These challenges will be solved by 12 PhD candidates hosted in 12 recognized and interdisciplinary organizations. A multifaceted research training programme has been designed to educate a new generation of PhDs and provide them with a unique skill set enabling them to tackle the great challenges we face to mitigate the decline of global biodiversity. WildBotics will raise the level of excellence in doctoral programs and simultaneously enhance the career perspectives of the PhDs in both academia and industry.

Keywords: drones,autonomous systems,robots,computer vision,nature conservation,sampling,edna
Understanding the new oxidative paradigm of biomass waste upcycling (LyticPol)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 1
Project status: TERMINATED

As the EU is committed to becoming the world’s first climate-neutral continent, fossil fuels need to be replaced by sustainable alternatives. A potential alternative is the upcycling of lignocellulosic biomass to biofuels. However, the cost-efficient generation of biofuel from cellulose is considerably hindered by the recalcitrance of the cellulose biopolymer. In 2010, the discovery of a new family of copper-dependent metalloenzymes called lytic polysaccharide monooxygenases (LPMOs) spurred great hopes as LPMOs were shown to significantly boost the degradation of cellulose and other polysaccharides. Today, eight families of LPMOs have been classified with remarkably diverse substrate specificities and regioselectivities. Furthermore, the metal active sites are in rather different surroundings. Despite combined efforts from experimental and theoretical sides, the reaction mechanism of LPMOs has remained elusive. The here proposed “LyticPol” project suggests that previous theoretical studies lacked general conclusions because they (i) considered too few LPMO families and (ii) employed insufficient theoretical methods for the enzyme environment. The “LyticPol” project aims at elucidating the reaction mechanism of LPMOs, by using a novel theoretical method on a large set of representative LPMO structures. From knowing the mechanism, the reaction conditions of LPMOs can be fine-tuned and the full industrial potential can be reached. This is expected to have substantial economic and social impact. Hence, the results of the “LyticPol” project will be communicated not only to scientific experts but also to the general public. The project will be carried out by Dr. Erna K. Wieduwilt (EKW) under the supervision of Prof. Erik D. Hedegård at the University of Southern Denmark. The project itself and the training of EKW will contribute decisively to her career goal of becoming an innovative and independent researcher in the field of theoretical bio-inorganic chemistry.

Keywords: lytic polysaccharide monooxygenases,qm mm methods,density functional theory,polarizable embedding
Synchronised neuro-Memristive Architecture for Reinforced learning Technology (SMART)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Netherlands,Switzerland
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-11-30
Duration (months): 27.0
Total project cost (EUR): 203464.32
EU funding (EUR): 203464.32
Participants: 2
Project status: TERMINATED

Rapid progress in the regime of Artificial Intelligence and Internet-of-Things has enthused the development of fast and energy-efficient hardware to support future computing needs. One of the most prominent solutions is the deployment of cross-disciplinary resources for mimicking the performance of a Human Brain, also known as neuromorphic computing. It relies on electronic components that could replicate the functioning of neurons and synapses. Designing such novel electronics needs the development of cost-effective, fast and reliable materials with tunable functionality. A fundamental understanding of these materials will pave the foundation of innovative device designs and strategies for their large-scale integration for neuromorphic architectures. In this context, the proposed project intends to deliver artificial neurons by developing thin-films of a novel material (TbMnO3) that is capable of demonstrating a Negative Differential Resistance (NDR). The idea is to utilise the fundamental understanding of multi-dimensional (electrical, optical, mechanical and magnetic) control of NDR which is not explored yet and is possible in TbMnO3. NDR enables a two-terminal device to display self-oscillations due to applied electrical spikes. The spiking electrical currents could be used to govern the behaviour of these oscillations and emulating the leaky, integrate, and fire behaviour of biological neurons. Once such a performance is achieved, the device will further be integrated into oscillatory neural networks array for demonstration of complex computing tasks such as image recognition and imitating human behaviour. The project will unite the applicant’s expertise in synaptic devices and materials engineering with the extensive experience of the host-labs in thin-film and neuromorphic devices. Importantly, the project will warranty catapulting the applicant’s international recognition as an independent researcher and will improve his career prospects.

Keywords: thin films,epitaxial heterostructures,strain engineering,oxide electronics,brain inspired devices
Toward a Computational Theory of Legal Complexity (CompLex)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Finland
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 1499240.0
EU funding (EUR): 1499240.0
Participants: 1
Project status: SIGNED

Combating climate change, safeguarding democracy, regulating Artificial Intelligence: Societies worldwide are facing a deluge of urgent and fundamental challenges. Legal systems play an essential role in addressing these challenges, but many of them are struggling to respond effectively. Improving the capacity of our legal systems to handle current and future challenges requires novel tools for analyzing and monitoring legal systems. Complexity science provides a framework for developing these tools, permitting the principled and systematic study of law as a complex system—an evolving network of diverse agents that interact via adaptive, rule-based behaviors and make interdependent choices. CompLex will work toward a computational theory of legal systems as complex systems. Drawing on concepts and techniques from computer science and network science, the project will contribute the main building blocks of such a theory: multilayer maps to capture the relationships between the components of legal systems, meaningful measures characterizing their interdependencies and interactions, and mechanistic models that explain our observations and guide us in improving our systems. The methods resulting from CompLex will allow scientists, policymakers, and the general public to better understand and mitigate critical challenges faced by legal systems today—such as ensuring their robustness to attacks, their resilience to failures, and their adaptation to changing environments. CompLex builds on my pioneering work in developing the methodological toolkit for studying legal systems as complex systems, and it is enabled by my unique background, which combines expertise in law, computer science, and network science. By devising a computational framework for studying legal systems as complex systems and demonstrating its practical utility, CompLex will introduce a novel paradigm in our treatment of legal systems, catalyzing a computational complexity turn.

Keywords: legal networks,legal data science,computational legal studies,complex networks,network science,empirical legal studies,law and artificial intelligence
Dementia in Ankara and the Nature of Surroundings: The effects of everyday home and family environments on the health, well-being and identity of aging women (DEMANS24-26)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Türkiye
Call: ERA Fellowships (HORIZON-WIDERA-2023-TALENTS-02, 2023)
Start date: 2024-09-09
End date: 2026-09-08
Duration (months): 24.0
Total project cost (EUR): 132638.4
EU funding (EUR): 132638.4
Participants: 1
Project status: SIGNED

The COVID-19 pandemic continues to have a globally disproportionate impact on the well-being of people living with dementia – particularly those who are community-dwelling – who have seen reduced access to healthcare and increased risk of loneliness, isolation, and depression. Consequently, the 'home' has become a vital space of care that remains lesser-researched in dementia studies. This can be richly explored in the country of Türkiye, which borders the West, East, and Global South, and has a distinctly blended modern and collectivistic outlook regarding familial ties and gender roles. Focusing on Türkiye’s capital city, Ankara, this project will explore the physical (natural, built, material, biophilic) and social (spousal, familial, communal) features of home environments, examining the relations between dementia, place-based experiences, daily living, and well-being. Inspired by integrated theories on relational and in-the-moment well-being, this project adopts a mixed methods case study design and asks the overarching research question: "How do everyday interactions with both physical and social features of home environments promote or hinder the health, well-being and identity of older women living with dementia?". This timely holistic project seeks to develop new scientific knowledge about the complex relations between, and intersectionality of, dementia, gender, landscapes, socio-economic status, familial dynamics, and daily living in the context of Türkiye. The research has strong interdisciplinary links across architecture, human geography, anthropology and gerontology, with exchange of knowledge between the candidate and host, Bilkent University's Interior Architecture and Environmental Design department. The findings coincide with UN and EU research plans, will fulfil an existing knowledge gap on people living with dementia in Turkish urban landscapes, and will lead to outputs on future dementia-friendly designs of urban-based apartments and housing.

Keywords: ankara,alzheimer s,covid 19,dementia,everyday geographies,family dynamics,home environment,identity,interior,moments,landscape,older women,relational,socio material,t rkiye,well being
Breakthrough Water Vapor Driven Turbo-Compression System for Sustainable, Thermal, Advanced Cooling (DEOS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Denmark
Call: Green Deal innovations for the Economic Recovery (HORIZON-EIC-2021-ACCELERATORCHALLENGES-01, 2021)
Start date: 2022-07-01
End date: 2024-06-30
Duration (months): 24.0
Total project cost (EUR): 3527556.0
EU funding (EUR): 2469289.0
Participants: 1
Project status: CLOSED

STAC Technology has designed and developed a breakthrough system that can solve a major sustainability issue surrounding the future of space cooling; how to grow access to this essential need while diminishing its terrible impact on the environment. Our patented water vapor driven turbo-compressor technology powers a potentially near-zero-emission, plug-and-play refrigeration system (DEOS) that produces a pumpable ice slurry with 7x the cooling capacity of existing solutions, delivering 40% reduction in greenhouse gas (GHG) emissions, energy consumption reduction by 10% compared to NH3 cooling and heating and 62% compared to HFC-cooled AC units. Our system has been designed to exceed the performance and efficiency standards of current District Cooling (DC) and District Heating & Cooling (DHC) networks, bolster returns from existing networks, accelerate growth plans in underserved markets and deliver more sustainable cooling.

Keywords: district cooling,energy management,environmental and green technologies,energy efficiency,engineering and technology,design innovation,ice slurry,water,refrigerant,automation and control systems