Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
First real-time fact-checking tool to fight against the fake news and disinformation (NEWTRAL)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-03-01
End date: 2019-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

People consume news because they need to be informed about the state-of-the-world and events around them, but 54% of citizens think that there is a serious problem regarding fake news and trust in media has decreased to the lowest-point-ever. It is very difficult for citizens to assess the credibility and veracity of news. On the other hand, citizens’ trust is crucial for news media that look for solutions to fight fake news and increase citizens’ trust. The solution is fact-checking, but fact-checking is a very time-consuming and costly task. Newtral is a startup funded in October 2017 with fact-checking as its core business becoming one of the fact-checking pioneers and the leaders in the EU. +40 people currently work in Newtral researching new ways of producing and distributing data-driven journalism in the digital era, being the biggest professional fact-checking team in the EU. Our team is behind the production of ‘El Objetivo’, the first TV-show (+1M weekly live viewers) in the EU to bring fact-checking to a TV format in prime time. Newtral is also a leading member of the International Fact Checking Network (IFCN), a community of international fact-checkers (51 members) and the only member with a TV show in prime time. ‘El Objetivo’ has been awarded with the “Best Audiovisual journalist fact-checking projects award” by the IFCN. Our ambition is to create a new market by turning professional fact-checking into a scalable and profitable business. Newtral intends to become the gold standard in the fact-checking sector by applying NLP, advance data science methods and AI to the journalism fact-checking work to semi-automate the verification allowing any fact-checking journalist to become a ‘fact-checking centaur’. SME Instrument Phase-1 and Phase-2 will be extremely beneficial in helping the company to accelerate development and market expansion of the solution, boosting the company’s growth to +100 employees and 32M€ revenues by 2024.

Keywords: fake news,disinformation,fact checking
Traffic Safety Cultures and the Safe Systems Approach – Towards a Cultural Change Research and Innovation Agenda for Road Safety (TraSaCu)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria,Estonia,Albania,Albania,Greece,Türkiye,Finland,United States,Netherlands,Kosovo
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2015-03-01
End date: 2018-02-28
Duration (months): 36.0
Total project cost (EUR): 499500.0
EU funding (EUR): 499500.0
Participants: 13
Project status: CLOSED

Traffic Safety Culture (TraSaCu) aims at developing a cultural approach in road traffic safety research and accident prevention. Traditional approaches to traffic safety shall be complemented by a cultural perspective which has emerged recently in safety research and prevention. Safety culture has been identified as an important factor of road safety as it helps understanding and explaining the typical patterns of risk perception and risk taking that prevail in different national, regional or local traffic systems as well as their relationships with numbers and forms of accidents. A weak safety culture produce higher numbers of accidents which are more severe. A strong safety culture helps reducing the number of accidents as well as mitigating their severity. It strengthens safety relevant attitudes and behaviour and it is also a condition for making road safety measures more effective. According to a working definition of the US Department of Transportation Safety Council (US DOT), traffic safety culture is defined as the shared values, actions, and behaviours that demonstrate a commitment to safety over competing goals and demands. However, a unified concept of safety culture still does not exist. Therefore, the project will elaborate an empirically grounded and theoretically adequate concept of traffic safety culture, based on this definition by conducting a number of case studies of different traffic safety cultures across Europe. It focuses on the safety cultures that emerge under different institutional, demographic and topographical conditions and their influence on the numbers and forms of accidents. Research focuses on the culturally mediated interaction between traffic participants and their environment in terms of the cultural patterns of risk taking and risk perception. It also looks at those cultural elements that can be changed easily in order to improve road safety of the investigated traffic systems.

Keywords: traffic safety culture,mobility behaviour,road safety,action framework
GEOSS Platform Plus (GPP)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: Coordination and support actions
Countries involved: France
Call: Delivery of knowledge for climate adaptation and mitigation through the GEOSS infrastructure (Global Earth Observation System of Systems) (H2020-IBA-CROSS-GEOSS-2021, 2020)
Start date: 2022-01-01
End date: 2024-12-31
Duration (months): 36.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The GEOSS Platform Plus (GPP or GP+) project is an ESA-led, EC H2020 co-funded contribution to the implementation of the Global Earth Observation System of Systems (GEOSS) starting 1st January 2022 with a duration of 3 years. GPP is aimed at evolving the European GEOSS Platform components to enable access to tailor-made information and actionable knowledge and will do so in close collaboration with different GEO partners (a.o. via the GEOSS Infrastructure Development Task Team) with a user-centric approach. GPP will focus on services to non-specialists in the domain of adaptation to extreme climatic events and to changes in climatic conditions. Drivers for this will be (i) the lessons-learned from the evaluation of the implementation of the EU Strategy on Adaptation to climate change (COM(2018)738)), (ii) the priorities identified under the European Green Deal and (iii) the requirements expressed by the Mission on Adaptation to Climate Change including Societal Transformation. The project aims to fully exploit the GEOSS infrastructure and its components to the benefit of the users, to enable the connections with the data providers (including in-situ), which are relevant for the achievement of use cases, and to provide a user-friendly, up-to-date and therefore familiar environment, by making sure that the current trends in information technology are considered and exploited as necessary. By establishing synergies with relevant initiatives in the European landscape, GPP will concur to reinforce the European participation and leadership in GEOSS.
Nonlinear spatiotemporal light bullets: origin and stability (NOSTER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-11-01
End date: 2023-10-31
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: SIGNED

The NOSTER project is about unveiling the dynamics and features of spatiotemporal coherent structures emerging in multimode optical fibers, such as spatiotemporal solitons, also known as light bullets. Solitons are particle-like states, emerging due to a double balance between linear and nonlinear processes, that maintain their shape while propagating in a medium. Solitons arise in a large variety of different natural media, ranging from hydrodynamics and plasma physics, to nonlinear optics and biology. In nonlinear optics, the emergence of solitons is related to the light confinement in time or space. One basic example of a system yielding to this type of state are single mode optical fibers, where the Kerr nonlinearity counteracts the spreading of the light produced by the chromatic dispersion. In multimode optical fibers, temporal and spatial effects, such as chromatic dispersion and diffraction, can occur simultaneously and counteract the Kerr nonlinearity, leading to the space-time confinement of light, and therefore, to the formation of much more complex coherent structures. My approach in this project is to predict and analyze the generation of localized spatiotemporal states, in particular light bullets and vortices, from a pattern forming and bifurcation theory perspective. Applying advanced analytical and numerical methods, I will first elucidate the origin of light bullets, characterizing their dynamics and bifurcation structure. In a second step, I will study the dynamical properties of optical vortices and the potential transition to optical turbulence. In both cases, their interaction dynamics, and the influence of high-order effects and losses will be analyzed. The understanding of such complex dynamics is crucial, and it will enable a tremendous breakthrough in many technological areas such as high-power multimode fiber lasers, optical communication systems, and a large variety of other industrial and biomedical applications.

Keywords: solitons,vortices,localized structures,nonlinear optics,photonics,multimode optical fibers,spatiotemporal phenomena,bifurcation theory,dynamical systems
The inhibition of sorting proteins as a therapeutic avenue in HER2 positive breast cancer (SaveHER)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Finland
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2018-03-01
End date: 2019-08-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

HER2+ breast cancers are an aggressive type of breast cancer and have a poor prognosis. There are many therapies currently on the market to target this type of cancer, however they fail to deliver effective clinical results due to therapy resistance. In our ERC-CoG project, we found that proper endosomal trafficking is required for functional HER2 oncogenic signalling at the plasma membrane. Targeting HER2 endosomal traffic can result in effective treatment of HER2+ cancers, without the risk of therapy resistance. As such, this innovation could deliver the first truly effective cancer treatment for HER2+ breast cancer patients that do not respond to current treatments. In this ERC-PoC, we aim to prove that therapeutic targeting of endosomal traffic is effective in HER2+ cancer models in vivo, as a monotherapy and synergistically with current therapeutic antibodies, and to explore the commercial avenues to exploit this finding.

Keywords: breast cancer,her2,targeted therapy,drug resistance
Saline Fluids in the Mantle - Experimental Investigation of Their Role in Diamond Formation and Kimberlite Magmatism (SalFluMa)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-02-01
End date: 2020-01-31
Duration (months): 24.0
Total project cost (EUR): 159460.8
EU funding (EUR): 159460.8
Participants: 1
Project status: CLOSED

The majority of natural diamonds that have great economic importance for the gem industry are formed at great depth beneath old continents in the subcontinental lithospheric mantle (SCLM). The main carrier of these diamonds are kimberlites, deep volcanic rocks that transport fragments of the SCLM to the Earth’s surface. Both diamond formation and kimberlite genesis are still heavily debated processes in the Geosciences. Growing evidence from natural samples, such as fluid inclusions in diamonds, suggests that chloride-bearing fluids may play an important role in diamond formation and possibly in kimberlite generation. These saline fluids are envisaged to percolate into the SCLM from slabs of oceanic crust that are subducted underneath the continents. The proposed research will investigate this hypothesis from an experimental perspective. High-pressure and temperature experiments, performed at the Institute for Mineralogy at the University of Münster (WWU), will examine the reactions between saline fluids and different rock types that constitute the SCLM. The reaction products will be evaluated by micro-analytical methods, and their compositions compared to natural samples and to kimberlitic melts. These petrological experiments are completely novel and indispensable in testing existing hypotheses on diamond formation and kimberlite generation. The applicant is new to the field of experimental petrology, but brings along a wealth of complimentary experience. During his Diplom and PhD research (at the University of Mainz and the University of Alberta, respectively) he has worked with a wide range of analytical methods and gained profound knowledge of kimberlites, diamonds, and phase equilibria of the mantle. The WWU would benefit from the applicant’s previous research experience and his contacts in academia and industry. In return, the applicant would greatly benefit from a transition into experimental petrology at one of Europe’s top research institutes in this area.

Keywords: experimental petrology,high pressure high temperature experiments,diamond formation,kimberlite formation,saline fluids,subcontinental lithospheric mantle
Characterization of islet-specific CD8 T cells in the honeymoon of type 1 diabetes (HONEYDIAB-8)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-15
End date: 2019-09-14
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Type 1 Diabetes (T1D) is a metabolic disease that results from the autoimmune attack against insulin-producing β-cells in the pancreatic islets of Langerhans. T1D usually comprises a phase called ‘honeymoon’, an interesting though poorly studied period of the disease where exogenous insulin requirements are decreased, postulating a possible attempt of β-cell regeneration and a remission of the autoimmunity. The proposed research aims to identify and characterize islet-specific CD8 T cells, the final effectors of β-cell death, in the honeymoon of T1D. We plan to perform a cross-sectional and longitudinal study with T1D patients where the immunological and metabolic characterization will be collected during the first year of the disease, and analysed by flow cytometry, enzyme immunoassays, gene expression and functional assays. The project addresses the characterization of the following unknown immunological features, pursuing a novel concept in T1D field: the role of antigen-specific CD8 T cells in the modulation of autoimmune response in the honeymoon phase. There will be technological and fundamental Immunobiology advances provided by the opportunity to analyse effector cells in these unusual effector memory differentiation states, which presumably reflect chronic exposure to self-antigens. Finally, the highlighting of suitable T-cell related biomarkers for the honeymoon could help in the early identification of the patients with best tolerance re-establishment potential, as well as providing an optimized follow up of future immunotherapies. There are very few studies of key immunology processes as they relate to human metabolism in vivo, and the applicant will learn how to oversee these. The high-quality and originality of the proposed research will open up the best career possibilities for the applicant through and its novelty could also involve industry collaborations.

Keywords: type 1 diabetes,honeymoon,antigen specific cd8 t cells,autoimmunity,biomarkers
Understanding the molecular mechanisms controlling the orientation of plant cell divisions (TORPEDO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cellular, Developmental and Regenerative Biology
Panel description: Structure and function of the cell, cell-cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Belgium
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-02-01
End date: 2022-07-31
Duration (months): 66.0
Total project cost (EUR): 1499937.5
EU funding (EUR): 1499937.5
Participants: 1
Project status: CLOSED

Due to the presence of a rigid cell wall, plant cells are fixed within their tissue context and cannot move relative to each other during development. Plants thus need to rely on directed cell elongation and cell division to generate a full three-dimensional (3D) structure. Controlling cell division orientations relative to the tissue axis is therefore the fundamental basis for 3D growth. In the root, plant cells are organised in cell files and undergo two main types of cell division to allow directional growth: anticlinal cell divisions (AD, adding cells within a cell file) and periclinal cell divisions (PD, creating new cell files, organs and tissues). Understanding the mechanisms that control cell division orientation is a key question in developmental biology and the main focus of this application. PDs are challenging to study as they only occur sporadically and typically in the most inner tissues of the root. I recently constructed a powerful system to induce strong, fast and homogenous PDs in any tissue type. I therefore now have the perfect tool at hands to tackle the fundamental question of how plants control the orientation of its cell divisions by: 1. Understanding the cellular events that occur prior to PD using a set of complementary techniques. 2. Identifying novel downstream components that translate the known genetic triggers for PD into changes in cell division orientation by performing an unbiased genetic screen. 3. Determining the developmental specificity and convergence of the known genetic pathways capable of inducing PD through studying their transcriptional targets in an ectopic tissue context. 4. Establishing a cell-culture based system for genetic and high throughput chemical perturbation studies of cell division orientation. I thus aim to perform a global and comprehensive study of cell division orientation, a process crucial for 3D growth in general and vascular development in specific.
European Joint Programme for the Integration of Radiation Protection Research (CONCERT)

Framework: Horizon 2020 — Euratom
Programme: Nuclear fission and radiation protection
Theme: Radiation protection
Action type: COFUND actions
Partnership:  (EJP-COFUND)
Countries involved: Austria,Germany,Germany,Spain,Estonia,Italy,Italy,Austria,Spain,Germany,Germany,Germany,Germany,Ireland,Italy,Germany,Norway,Belgium,Finland,Finland,Greece,Slovenia,Sweden,Slovakia,Switzerland,Hungary,Lithuania,Belgium,Bulgaria,Finland,Greece,Croatia,Croatia,Hungary,Poland,Poland,Romania,Latvia,France,France,France,Czechia,Czechia,Netherlands,Denmark,United Kingdom,United Kingdom,United Kingdom,Portugal,Denmark,United Kingdom,United Kingdom,United Kingdom
Call: Integrating radiation research in the European Union (NFRP-2014-2015, 2014)
Start date: 2015-06-01
End date: 2020-05-31
Duration (months): 60.0
Total project cost (EUR): 31986747.7
EU funding (EUR): 19822878.0
Participants: 80
Project status: CLOSED

The proposed European Concerted Programme on Radiation Protection Research (acronym: CONCERT) aims to contribute to the sustainable integration of European and national research programmes in radiation protection. It will do so by focusing resources and efforts in five key directions: • Bring together the elements of the European scientific communities in the fields of radiation effects and risks, radioecology, nuclear emergency preparedness, dosimetry and medical radiation protection, whose joint expertise is essential to continue the development of radiation protection knowledge in a multidisciplinary mode to reduce further the uncertainties in radiation protection. • Strengthen integrative activities between the various areas of expertise, in particular biology, biophysics, epidemiology, dosimetry and modelling as well as fostering the use of existing infrastructures and education and training activities in radiation protection. • Stimulate and foster scientific excellence, by setting up and co-funding advanced research programmes with the potential to enhance current knowledge and the scientific evidence base for radiation protection. • Exchange and communicate with all stakeholders, including the professional organizations concerned with radiation protection, the regulatory organizations across Europe, the public and media where necessary, and the international community of scientific, technical, legal and other professional experts in radiation protection. • Foster the harmonious application of available scientific basis for radiation protection practices across Europe, by bringing together scientific and technical expertise in radiation protection issues, standard setting know how, particularly with respect to the implementation of the Euratom Basic Safety Standards (BSS) at the legal, administrative and operational level. To reach its goals, CONCERT will have seven Work Packages each of which will focus on each of the key directions.