Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Solar operational Lifecycle and Asset Reliability Intelligency System (SOLARIS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Denmark,France,Austria,Spain,Italy,Germany,Israel,Greece
Call: Operation, Performance and Maintenance of PV Systems (HORIZON-CL5-2023-D3-02, 2023)
Start date: 2024-07-01
End date: 2028-06-30
Duration (months): 48.0
Total project cost (EUR): 5848122.5
EU funding (EUR): 4992551.38
Participants: 15
Project status: SIGNED

In order to foster the development and integration of PV systems in Europe and beyond, more efficient, reliable and profitable operation and maintenance (O&M) strategies need to be found. In this context, SOLARIS will gather 15 partners (6 research-oriented partners, 8 industrial partners including 2 start-ups & 3 SMEs, and a municipality) for 48 months to develop and demonstrate a complete set of physical and digital tools for improved forecasting, operational performance and maintenance, resulting in high performance index (90%) and availability (>98%) of PV plants, and decreasing the levelised cost of energy by 10%. SOLARIS will provide operators with reliable forecasting (short and long-term weather and power production); accurate monitoring and inspection techniques through novel wind, dust and impedance sensing, as well as automated multi-spectral PV inspection using drones; early fault detection (incl. preventive maintenance); improved lifetime of strategic components through adapted responses (self-protection, power electronics’ reconfiguration, storage strategies); and energy trading via an AI-based tool. Demonstration data will be gathered in an IoT platform, feeding one of the main tools proposed to PV operators, i.e. the PV asset management software. All developments will be demonstrated and assessed in 8 use-cases (utility- and small-scale ground-mounted, rooftop, floating, agriPV) across Europe. Demonstration datasets and labelled data on the different use-cases, as well as long-term PV potentials for regions of demonstration will be shared publicly to foster developments of other initiatives. The uptake of SOLARIS developments will be enhanced by the wide dissemination of demonstration and assessment results to relevant stakeholders, i.e. PV systems owners and O&M firms, as well as technology providers. It will be further facilitated by the creation of a Stakeholder Forum, accompanying all developments towards commercialisation.

Keywords: pv systems operation and maintenance,performance,artificial intelligence,monitoring,inspection,fault detection,market uptake commercialisation
Advanced Integrated Renewable Wind Innovation for Nautical Gains (AIRWING)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499999.0
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

The project by GT Green Technologies aims to advance wind propulsion technology for the maritime industry through the development and deployment of their patented AirWing™ system. This innovative solution seeks to significantly reduce fuel consumption and greenhouse gas emissions for commercial shipping vessels, addressing the environmental impact of the global shipping industry, which is a major contributor to pollution. GT Green Technologies specialises in marine wind propulsion systems. Our mission is to offer solutions that cut fuel use and emissions. AirWing™ is a modular and retrofittable hybrid sail designed to fit in limited deck spaces without disrupting cargo operations. AirWing™ utilizes a hybrid suction sail/rigid wing design, generating high lift and thrust for significantly improved fuel efficiency and reduced emissions. The system is designed for easy installation and minimal operational disruption, with a compact stowable configuration suitable for various vessel types. AirWing™ outperforms existing wind propulsion technologies by offering higher thrust relative to its footprint, making it suitable for vessels with limited deck space. It is modular, cost-effective, and can be pre-assembled, reducing installation time and costs. The AirWing™ 20 model has already demonstrated the potential for significant fuel savings and emission reductions, but larger models are needed to cater to a broader range of vessel sizes. The project seeks to bring AirWing™ 40 and 40XL to market readiness, addressing the needs of larger vessels and expanding the potential impact on global shipping emissions. The requested funds will drive the adoption of this game-changing technology in the maritime industry. With this innovation, GT Green Technologies aims to revolutionize ship propulsion, contributing to global efforts to decarbonize the maritime sector and achieve international climate targets.

Keywords: wind propulsion,shipping emissions,decarbonization
A highly efficient CRISPR/Cas9 gene editing method for difficult to transform arthropods (CRISPART)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Belgium
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2023-09-01
End date: 2025-02-28
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

During the ERC consolidator grant POLYADAPT, an efficient gene editing system was discovered which allows to genetically transform the spider mite, Tetranychus urticae, a main crop pest. This species belongs to the chelicerates, the second largest group of arthropods including mites, ticks and spiders, that are notoriously difficult to transform. Our invention not only accomplished for the first time gene knock-out in mites, but also allows precise gene editing via knock-in with high efficiency. The method results in a 20-fold increase of transformation efficiency. In the PoC CRISPART, we will demonstrate the efficacy of the invention on a wide range of difficult to transform arthropods and aim to better understand the mode of action of the observed synergy. We will further investigate the optimal validation trajectory of the invention, considering a gene editing service and investigate commercial and financial feasibility of the optimal path.
Biocultural Transmissions of Obesity across Generations in the Digital Era (OBICODE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Coordination and support actions
Panel: Social Sciences and Humanities
Countries involved: Portugal
Call: ERA Chairs (HORIZON-WIDERA-2023-TALENTS-01, 2023)
Start date: 2025-03-01
End date: 2030-02-28
Duration (months): 60.0
Total project cost (EUR): 2499991.07
EU funding (EUR): 2499991.07
Participants: 1
Project status: CLOSED

OBICODE aims to significantly improve the research performance of the University of Coimbra (Portugal) by implementing a robust interdisciplinary research line in the field of Anthropology. It will do so under the leadership of one of the most respected and highly cited researchers in the field, Professor Stanley Ulijaszek, Emeritus Professor at the University of Oxford (#1 in Anthropology, QS ranking) and Director of the Biocultural Variation and Obesity Unit (UBVO). OBICODE will use the holism principle of Anthropology to develop and test an integration model of the social origins of obesity within and across generations, under the influence of the digital ecosystem, including web 2.0, and translate it into policy and intervention messages. Other objectives include: a) implement a Doctoral Programme on Integrative Models of Obesity; b) establish a Life course Obesity Observatory and c) reinforce citizens' scientific and health literacy under a new contemporary societal framework of Anthropology, encompassing an integrative and biocultural perspective of obesity. OBICODE will promote an institutional reform that aligns the University of Coimbra with cutting-edge anthropological research provided by Anthropology Departments/Centres in non-widening European countries. To achieve this goal, the institutional reform under OBICODE will focus on: 1) attracting talents in the area of Anthropology; 2) improving research and education, by providing top notch training in an area that is central for resolving complex societal challenges such as obesity; and 3) bringing these scientific outputs to society. Overall, the scope of this action extends to the whole system: academia, target users (e.g., students), and the wider community, including policy and intervention. A team of prestigious and influential Anthropologists will advise on the different steps of the project, providing also a clear view for the future of Obesity studies.

Keywords: anthropology obesity social transmission digitalization science literacy health policy
Avodes - biotechnological menstrual product for Candidiasis prevention (Avodes-Biotech)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Lithuania
Call: Women TechEU (HORIZON-EIE-2021-SCALEUP-01, 2021)
Start date: 2022-06-01
End date: 2022-11-30
Duration (months): 6.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

372 million women globally have a silent torturer - recurrent vulvovaginal candidiasis (VVC) , which affects 3 out of 4 women at some point in their lives. Despite therapeutic advances, VVC remains a common problem worldwide, affecting all strata of society and being the second largest gynaecological infection. If it is left untreated, many complications have been appointed as its consequence, such as infertility, subsequent preterm delivery, suppression of the immune system, pelvic inflammatory disease, ectopic pregnancy, pelvic abscess, menstrual disorders and miscarriage. Avodes has developed an innovative medical device for menstruation - a patented anatomically shaped “moist sponge” made of completely natural, biodegradable materials (biodegradable within 1 month). It protects innate defence mechanisms of vaginal microflora during most vulnerable period – menstruation. Studies have shown, that fluctuating hormones and the resulting imbalance of vaginal flora cause an increased risk of a yeast infection every month. Unique Avodes biotechnological solution preserves women’s natural vaginal microbiota in the same time selectively inhibiting growth of pathogenic microorganisms. It reduces risk of vulvovaginal candidiasis (VVC) by 85 % thus effectively preventing the disease. Avodes is the only medical product designed to prevent infection, rather than deal with the consequences. Avodes effectively disrupts the vicious cycle of ”microbiota disbalance –> infection –> antibiotic/fungicidal treatment–> microbiota disbalance” and offers break-through solution which protects women’s health and the environment. Women Tech EU programme would support company in upgrading the business model, business and marketing plan, market validation and would help to find partners (clinical, manufacturing and commercial) as well as to prepare funding strategy. Successful project implementation will provide much needed tailwind to our company to bring the product to the market.

Keywords: biotechnologies,medical product for use during menstruation,candida prevention,fem tech,biotechnological menstrual product,candidiasis preventing menstrual product
Oral oxytocin for abdominal pain (GUTOCINS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Austria
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2023-06-01
End date: 2024-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Chronic abdominal pain is a widespread debilitating condition commonly associated with gastrointestinal disorders such as irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD). IBS and IBD affect more than 10% of the global population, leaving a severe and steadily growing socio-economic burden on society (€115 billion/year in Europe in direct and indirect health care costs). Adequate pain management for these conditions is imperative but remains challenging since classical analgesics are poorly effective, associated with adverse effects, and can even exacerbate disease progression. In this project, we will advance a new class of gut-stable peptide analgesics to target abdominal pain at its origin in the gut. This represents a highly innovative treatment strategy with a large safety window due to its gut-specific action and negligible risk of systemic off-target effects. It also addresses a long-standing problem in the peptide therapeutics industry, namely the lack of oral peptide drugs. The objective of this project is to optimise our patented lead compounds towards oral drug candidates and generate robust and supporting preclinical data for clinical translation. The proof-of-concept data will then be used to engage with industry partners and other supporters to advance these drug candidates into the clinic for the treatment of chronic abdominal pain. Our gut-specific treatment approach along with this new class of analgesics could induce a highly desired paradigm shift in how to treat chronic abdominal pain and gastrointestinal disorders, an area with unprecedented unmet medical need. This could benefit millions of people worldwide, improve their quality of life, and help reduce the substantial socio-economic burden that chronic abdominal pain has on society.
Directed and Responsive Oncology Nanoparticle-releasing microrobots from Engineered MagnetoTactic Bacteria (DroneMTB)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-14
End date: 2027-02-13
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

Given the prevalence of cancer, it is of utmost importance to develop new strategies to treat it. One of the most ambitious approaches is the use of microrobots, self-propelled microscopic devices capable of propelling themselves and being guided towards tumours where they can then effectuate a therapeutic action. Magnetotactic bacteria (MTB) are non-pathogenic aquatic microorganisms that synthesize intracellular magnetite nanoparticles within organelles called magnetosomes, and are ideal candidates to serve as microrobots for cancer theranostics. Suitably, they are highly motile, have preference for low oxygen conditions such as the inside of tumours, and can be externally guided, detected, and actuated by magnetic fields thanks to their chain of magnetosomes. In this project I propose a new approach to boost the therapeutic abilities of MTB by genetically engineering MTB to express immunotherapy-mediators on the surface of magnetosomes, and to create a triggered-release mechanisms to deliver these magnetosomes within the tumour microenvironment. This strategy, yet to be exploited, is more sustainable and cost-effective than the chemical-based approaches proposed to date. Specifically, new generations of MTB will maintain the genetic modifications without further need of surface modification or therapeutic loading steps. The perfomance and effectiveness of genetically modified MTB to swim towards and release the immunotherapy-mediating magnetosomes will be tested in vitro in 3D cancer cell models placed within microfluidic devices to mimic tumours and surrounding vasculature. DroneMTB is a highly interdisciplinary project that combines methods from materials science, microbiology, genetic engineering, biochemistry, microfluidics, microscopy, and cell biology. After carrying out the project I will have acquired necessary skills to become an independent scientist and to lead research projects in the field of biomaterials and biomedical applications.

Keywords: magnetotactic bacteria,microrobots,nanotechnology,biotechnology
MULTIFUNCTIONAL SELF-HEALING INJECTABLE HYDROGEL FOR CHRONIC WOUND HEALING AND TISSUE REGENERATION (INJECTHEAL)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Innovation actions
Countries involved: Italy,Austria,Germany,United Kingdom,Ireland,Spain,Switzerland
Call: Advanced biomaterials for the Health Care (IA) (HORIZON-CL4-2024-RESILIENCE-01-TWO-STAGE, 2024)
Start date: 2025-05-01
End date: 2028-04-30
Duration (months): 36.0
Total project cost (EUR): 7944558.04
EU funding (EUR): 7299588.8
Participants: 13
Project status: SIGNED

Chronic wounds affect over 305 million people worldwide, significantly reducing quality of life, accounting for 2-4% of EU healthcare costs. Current treatments for deep cavity chronic wounds lack a comprehensive strategy to tackle issues including wound reachability, infection control, inflammation reduction, vascularization, tissue regeneration and scalability. INJECTHEAL introduces a ground-breaking multi-functional, green 4D injectable self-healing hydrogel, based on functionalized pectin and gelatin, serving both as a delivery vehicle for therapeutics and a matrix to promote healing through its biomimetic properties and controlled bioresorption. The hydrogel platform includes antibacterial (e.g., octenidine), anti-inflammatory and pro-angiogenic (e.g., Ac2-26 peptide and siRNAs) agents, to provide effective formulations viable for industrial exploitation. Hydrogel properties are tailored by biocompatible poly(epsilon-lysine) dendrons allowing (i) fine tuning of hydrogel crosslinking degree and (ii) versatile bulk functionalization with bioligands to support cell adhesion, migration and angiogenesis. Immune-stealth polymeric microcapsules, embedded in the hydrogel, protect cell-targeted dendrons, loaded with sensitive agents, from enzymatic degradation enabling their controlled, sustained and precise delivery. Preclinical safety and efficacy assessment according to GLP are set with progressive complexity to reproduce human-relevant pathophysiological features of chronic wounds, from ISO standard in-vitro 2D cell trials and antimicrobial assays to novel in-vitro tests in proprietary human-relevant 3D skin models, human wound exudates and in-vivo animal chronic wound models. Scale-up production, business planning, consultation with key notified regulatory agencies and early involvement of end-users (incl. patients) will provide a preclinically-validated industrial socio-economical sustainable hydrogel platform ready for post-project first-in-man clinical trials.

Keywords: chronic wounds,tissue regeneration,multifunctional biomaterials,medical device,health economics,wound care management,injectable biomaterials
Entangled Universals of Transnational Islamic Charity (EntangledUniversals)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 1996384.0
EU funding (EUR): 1996384.0
Participants: 1
Project status: SIGNED

This project examines transnational Islamic charity as a global force. The goals of Islamic charity shifted in the long twentieth century, beyond a community-scale oriented towards rewards in the afterlife and construction of religious infrastructure for Muslims. Islamic charitable networks have invested in public works for all humans: state-of-the-art hospitals, multistorey housing complexes and schools for modern education. Transnational Islamic charity today claims 'humanity' as its constituency. As a universalist category, humanity is no longer the monopoly of Western humanitarianism. The project’s central objective is to study how Islamic charitable networks in seeking to address global needs position themselves as universalist projects, entangled with Western humanitarianism and neoliberal welfare regimes. Theorizing the unstable hierarchies of humanity embedded in transnational Islamic charitable work, it will lend new insights into its moral limits and potential – by addressing three questions: 1. How do Islamic charitable networks rearticulate the category of humanity to address diverse constituencies? 2. How do Islamic charities define and contribute to the public good within globalized neoliberal welfare regimes? 3. How do recipients of aid demonstrate their humanity to meet shifting criteria of worthiness? Though considered security threats by states, Islamic charities are increasingly recognised by multilateral institutions as important sources of welfare. In a time of multiple crises characterized by climate upheavals, religious polarization, economic instability and social deprivation, it is vital to understand transnational Islamic charity as a force for addressing universal needs. The project develops a novel analytical approach by centering two countries in the global south outside of the ‘traditional’ heartland of the Islamic world, India and Tanzania, to study charitable networks across the Indian Ocean and beyond.

Keywords: islam,humanity,welfare