Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Redefining Virtual Reality Therapy for Anxiety Disorders (NEOMENTO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2017-12-01
End date: 2019-05-31
Duration (months): 18.0
Total project cost (EUR): 148403.0
EU funding (EUR): 148403.0
Participants: 1
Project status: CLOSED

Social anxiety disorder (SAD) – the most common type of anxiety disorders – has severe emotional, financial and social consequences for patients, their families and their social network. Affecting about 7% of Europeans at some point in their life, SAD produces substantial societal cost due to long lasting treatments and extensive periods of reduced working capacity. To address this important problem, the project will establish an innovative system for treating SAD by exploiting the proven therapeutic potential of advanced Virtual Reality (VR) technology. SAD is predominantly treated with cognitive behavioural therapy, in which patients are repeatedly exposed to fear-provoking, social situations. However, patients often have to wait very long before treatment becomes available, exposure is rarely applied with the necessary intensity due to resource limitations, and objective measurement of treatment efficacy and dynamic adjustment of therapeutic scenarios is hardly possible. These problems can be overcome with VR based, controlled exposure to virtual renditions of fear provoking situations, which has been shown to surpass traditional therapies in terms of treatment efficacy, patient acceptance, and economic efficiency. Given that advanced VR technology has become very affordable, a widespread application of VR for the treatment of SAD is now within reach. The proposed project will fuse the applicant’s extensive VR expertise with established principles for VR based therapy to create an innovative system for the treatment of SAD. This system will, for the first time, combine interactive 3D environments with external physiological measures (e.g eye tracking data) and real-time data analyses techniques to provide a precise, flexible and time and cost-efficient therapeutic approach. Established collaborations with clinical partners will allow for continuous testing and refinement of the system, thus ensuring that market readiness can be achieved within the funding period.

Keywords: virtual reality,exposure therapy,anxiety disorders,software development,physiological markers
Single Point Of aTtachment communications empowered by cLoud computing and bIG data analytics running on-top of massively distributed and loosely-coupled Heterogeneous mobile data neTworks (SPOTLIGHT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Italy,Germany,Cyprus,Sweden,Greece,France,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2016, 2016)
Start date: 2017-01-01
End date: 2021-06-30
Duration (months): 54.0
Total project cost (EUR): 3813484.32
EU funding (EUR): 3813484.32
Participants: 11
Project status: CLOSED

To handle the unprecedented demand for mobile data traffic, different vendors, operators and research programmes have aimed to develop radio access technologies (RATs) that boost physical-layer link capacity, utilize millimeter wave radio, or further densify network topology. Notable steps have also been made towards shifting baseband processing from the (currently) ultra dense network edge to a central location where coordinated resource management will be performed. Nonetheless, the today’s mobile network ecosystem includes vastly heterogeneous, evidently overlapping (in coverage) and fully isolated (in operation) attachment points that still handle most of the functions necessary for mobile data communications independently. Aiming to meet and surpass the requirements set for the 5G-and-Beyond mobile data network, in SPOTLIGHT we will create a fully-integrated and multi-disciplinary network of Early Stage Researchers (ESRs) that will analyze, design, and optimize the performance of a disruptive new mobile network architecture: the SPOTLIGHT architecture. This architecture promises to break performance limitations present to the currently loosely inter-connected, resource-fragmented and isolated in operation mobile network ecosystem, by transforming the currently loosely-coupled multitude of heterogeneous and multi-layered RATs to a flat coalition of massively distributed antenna sub-systems that are optimally orchestrated by a cloud-empowered network core. Our primary aim will be to support for the first time self-including yet ultra-reliable radio communications at the edge network. To further reduce response time and enhance network resilience, all functions necessary for mobile communications will be subject of i) massive parallelization in cloud platforms at the network core and ii) big data analysis running on-top of a virtual pool of shared energy, radio, computing and storage resources at the network.

Keywords: 5g technologies,massively distributed mimo,popular content delivery
TAking a Reflexive approach to Gender Equality for institutional Transformation (TARGET)

Framework: Horizon 2020 — Science with and for Society
Programme: Promote gender equality in particular by supporting structural change in the organisation of research institutions and in the content and design of research activities
Action type: Coordination and support actions
Countries involved: Italy,Italy,Spain,Austria,Cyprus,Serbia,Greece,Romania,France,Morocco
Call: Support to research organisations to implement gender equality plans (H2020-SwafS-2016-1, 2016)
Start date: 2017-05-01
End date: 2021-12-31
Duration (months): 56.0
Total project cost (EUR): 1994952.51
EU funding (EUR): 1994952.51
Participants: 11
Project status: CLOSED

TARGET will initiate institutional change in seven gender equality innovating institutions (GEIIs) in the Mediterranean basin – including research performing organisations (RPOs), research funding organisations (RFOs) and a network of universities. TARGET takes a reflexive approach which goes beyond the formal adoption of a gender equality plan by emphasising an iterative reflection of progress made as well as establishing a community of practice to effect institutional transformation. Actual change is the result of increased institutional willingness and capacity to identify, reflect on and address gender bias in a sustained way. Starting point and anchor of the process is a tailored Gender Equality Plan or Strategy (GEP/GES) in each GEII. TARGET will build the institutional capacity for a reflexive gender equality policy by: developing effective tools for each stage of the GEP/GES (audit, planning, implementation, monitoring, self-assessment) to be customised to the specific institution; supporting the development of competences to conduct a gender audit, to design, implement, monitor and self-assess a tailored GEP/GES; establishing a community of practice of relevant stakeholders within each GEII; initiating an organisational learning process within each GEII which combines self-assessment with GEP/GES evaluation. The TARGET countries have been characterised as relatively inactive in developing gender equality policies in R&I. To ensure that action taken has a multiplier effect, each GEII will undertake targeted dissemination activities to initiate a national/regional discourse on gender equality in R&I. Furthermore TARGET will develop new knowledge for institutions, practitioners and policymakers based on a comparative analysis of GEP implementation and sustainability to provide a basis for effective sharing of practice in both proactive and relatively inactive countries - taking into account differences in cultural, socio-economic and political settings.

Keywords: gender equality audit,gender equality plan,monitoring,self assessment,reflexive institutional,learning process
Systematic identification of genetic modifiers in the response to targeted therapies in acute myeloid leukemia. (AML-SynergyX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 186167.04
EU funding (EUR): 186167.04
Participants: 1
Project status: SIGNED

In the last decade, we have witnessed tremendous progress in understanding the genetic landscape of acute myeloid leukemia (AML), which has been translated into several approved targeted therapies. Although these therapies are effective initially, most patients eventually develop resistance through a variety of genetic and/or epigenetic mechanisms that remain incompletely understood. While it is widely accepted that transient responses to oncogene-targeted therapeutics into cure will require drug combinations, the pre-clinical and clinical development of rational combination therapies remains challenging. The advent of high-throughput genetic screens and transcriptome profiling methods fundamentally changes the way we can address this problem. The overall goal of this proposal is to apply and integrate these innovative technologies to deeply investigate genetic and gene-regulatory mechanisms in the response to small-molecule inhibitors of FLT3 and the MLL-Menin interaction, which hold promise as targeted therapeutics for more than 50% of AML patients. Using advanced CRISPR/Cas9- and shRNA-based screening platforms, I will systematically identify genes that modify the response to FLT3 and MLL-Menin inhibition. Complementary to functional-genetic screens, I will apply SLAMseq, a scalable time-resolved mRNA profiling method co-developed by the host lab, to dynamically investigate transcriptional programs underlying the primary response and adaptation to FLT3 and MLL-Menin inhibition. Functional-genetic and time-resolved transcriptome profiles will be integrated to select promising candidates for validation and mechanistic follow-up studies in patient AML samples and genetically engineered mouse models. In summary, by providing deep insight into the response to FLT3- and MLL-Menin inhibition, I thrive to identify candidate targets and new concepts for rational combination therapies that would address an unmet clinical need with a clear path towards clinical translation.

Keywords: myeloid leukemia,crispr,cas9 genetic screens,transcriptome profiling,slam seq,combination therapy
User-centric Middleware Architecture for Advanced Service Provisioning in Future Networks (CASPER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Italy,Greece,Greece
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2016-01-01
End date: 2019-12-31
Duration (months): 48.0
Total project cost (EUR): 1080000.0
EU funding (EUR): 1080000.0
Participants: 7
Project status: CLOSED

The current paradigm in service provisioning to future communication networks lacks thorough end-to-end interpretation from the quality viewpoint, while the end-users’/customers’ profiles and preferences are mostly not taken into account. The subjective perception of a provided service, known as Quality of Experience (QoE), is one of the most important factors for a user’s decision on retaining the service or giving it up, and the key parameter for enabling advanced customer experience management (CEM). The main objective of CASPER is to combine academic and industrial forces towards leveraging the expected benefits of QoE exploitation in future networks. In particular, CASPER will exploit the most recent approaches in communication networks, such as the Software Defined Networking (SDN) and the Network Functions Virtualisation (NFV), to design and implement a middleware architecture for QoE-driven service provisioning. The architecture will consist of three interlinked modules, one-to-one mapped to the three instrumental functionalities required for the beneficial exploitation of QoE: i) reliable, secure and passive QoE monitoring, ii) efficient, dynamic and objective QoE estimation, and iii) robust and real-time QoE-driven service management. The three modules will be optimised and released as an integrated solution, in order to accelerate the adoption of QoE-driven network service management. The cornerstone of this effort will be a carefully-planned inter-sectorial secondment programme for Experienced Researchers (ERs) and Early Stage Researchers (ESRs). Under this programme, CASPER is expected to foster the exchange of knowledge and strengthen the collaboration among academia and industry through a bidirectional knowledge-sharing approach, where the academic beneficiaries will contribute by conveying their knowledge in QoE analysis and modelling, while industrial beneficiaries will provide their expertise in service development and software implementation.

Keywords: quality of experience,network functions virtualization,middleware,service provisioning
Brilliant Researchers Impact on Growth Health and Trust in research. (BRIGHT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Italy,Italy,Italy,Italy
Call: European Researchers' Night (H2020-MSCA-NIGHT-2016, 2016)
Start date: 2016-06-01
End date: 2018-01-31
Duration (months): 20.0
Total project cost (EUR): 160000.0
EU funding (EUR): 160000.0
Participants: 7
Project status: CLOSED

The BRIGHT project aims at enhancing the visibility and perception of researchers among the general population in the Tuscany Region, simultaneously with all the European Researchers’ Night (ERN) initiatives. BRIGHT acronym means “Brilliant Researchers Impact on Growth Health and Trust in research”, wishing to underline the positive aspect of the research activity in order to convey a positive message to the general public. BRIGHT is planned in for two years - i.e. two events, one in 2016 and another in 2017 - and livens up not only two “nights” with entertaining and exciting events spread across the main Tuscany cities, but it also creates a lot of initiatives aiming at building permanent “Research Urban Trekking” paths leading towards the complete awareness of the researcher’s role in society. “Researchers make your life better!” is the guiding principle stemming from the passion, the enthusiasm and hard intellectual work of researchers’ daily work and how this contributes to the well-being of the general population. BRIGHT focuses on creating awareness on the important role played by researchers in addressing the great challenges ahead, such as health and wellbeing, new technologies, sustainable development, physical and biological challenges, cultural heritage. BRIGHT will be successful if it will be able to convince the population of the IMPACT of the researchers and the research's products for the development of the society, and to make people TRUST the researchers instead of being driven away by hoaxes with no scientific basis.

Keywords: researchers,awareness,health,culture heritage,research urban trekking paths,new technologies
Globalised governance norms and local management and business practices in Africa and on the Arab peninsula (MANAGLOBAL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Belgium,France,France,United Arab Emirates,Cameroon,Ghana,Senegal,United Kingdom,United Kingdom,Morocco
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2018, 2018)
Start date: 2019-01-01
End date: 2024-06-30
Duration (months): 66.0
Total project cost (EUR): 1564000.0
EU funding (EUR): 1499600.0
Participants: 17
Project status: SIGNED

MANAGLOBAL will explore the type of local management approaches that are practiced in selected African and Arab countries. It will explain how companies and subsidiaries become profitable and grow in emerging countries in order to highlight the gap between globalized norms and standards of management and the ordinary ways of locally doing business. These processes of adaption are considered as glocalisation or hybridization. MANAGLOBAL will show how hybrid and innovative forms of private companies' government can be shaped by the mobility of people, capital, goods and knowledge. It will also demonstrate that local business practices (so called "poor" governance, and "insufficient" managerial skills) may become economic opportunities. Our aim is to contribute to research on management through the development of a pioneering collaborative team of 16 African, Arab and European partners, from 8 countries, including researchers, business leaders, and institutional decision-makers. We will confronte 3 methodologies: - A collaborative empirical research applying similar research approaches in all participating countries. - The study of the background, education and careers of business managers of industrial and commercial enterprises of selected countries. - The collection of ethnographic data and the production of business-related and organization-based case studies Based on the results, MANAGLOBAL will develop a cutting-edge empirically evidenced theoretical framework on how business is conducted and organizations are managed in African and Arab countries. Moreover, the training of the next generation of managers of the region is planned via online courses and workshops. A strong training program and 340 months of secondments will assure an efficient and strong knowledge exchange, increasing skills on doing cross-cultural research on how business is conducted and organizations are locally and globally managed, and the career development of all the participants.

Keywords: economic sociology,economic anthropology,cultures,localisation,hybridization
Novel Dinuclear Late Transition Metal Catalysts for CO2/Olefin and CO2/Epoxide/Olefin Copolymerization (COOLEFIN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,United States
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-01
End date: 2021-09-30
Duration (months): 33.0
Total project cost (EUR): 219844.5
EU funding (EUR): 219844.5
Participants: 2
Project status: CLOSED

Polyolefins are the most produced class of polymers every year (>130 million tons in 2015). Despite intensive research and development in this field over the past 50 years, both in academia and in industry, the synthesis of polar polyolefin copolymers remains challenging. These copolymers are highly desirable, most notably as compatibilizing agent in polymer blends. The COOLEFIN proposal is aiming to develop a sustainable alternative method to synthesise polar polyolefin from CO2/olefin and olefin/CO2/epoxide copolymerization - two challenging reactions still under explored. These new materials will reduce the use of petrochemically derived starting monomers and open a new field of sophisticated materials with unique properties. The COOLEFIN objectives are i) the synthesis and characterization of a new family of dinuclear late transition metal catalysts; ii) testing the series of catalysts for CO2/olefin and olefin/CO2/epoxide copolymerization; iii) physical characterization of the produced polymers; iv) kinetic and mechanistic studies of the polymerization reactions; v) optimization of the reactions conditions and scale up. The COOLEFIN action proposes a multidisciplinary research project on the frontier between inorganic, catalysis and materials chemistry, providing an optimum training experience and transfer of knowledge between all parties during both phases. In addition, the high impact of the study will be both of academic and industrial interest. It will put light to i) mechanism/rate of simple organometallic reactions (CO2/ethylene insertion); ii) the requirements for a good catalyst to perform these two polymerization reactions; iii) the link between the polymer micro/macrostructure and its physical properties to target specific applications. This project is a value added effort to bring two excellent polymerization concepts to the frontier of polymer catalysis research, which has never been given proper attention, despite being extremely promising.

Keywords: dinuclear complexes,olefin polymerization,carbon dioxide,epoxide copolymerization,block copolymers
Fiber Laser fOr ultRafast InfrareD Applications (FLORIDA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-03-27
End date: 2023-04-30
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

The goals of this Fellowship, entitled "Fiber Laser fOr ultRafast InfrareD Applications" (FLORIDA) are: (i) to train a talented Fellow (Dr. Wang) through research and tailored training programme, (ii) to provide opportunities for mutually beneficial knowledge exchange between EU host/co-hosts and the Fellow in the areas of high EU priorities, (iii) to design and develop a high-power all-fiber laser system of chirped pulse amplification (CPA) at the edge of the mid-infrared (MIR) wavelength range, and (iv) to demonstrate the fiber laser system's potential in nonlinear optics in the MIR. Such a stable, powerful MIR CPA fiber system will have a significant impact on science and technology, as it will open doors towards emerging MIR laser-based science and numerous applications. Various cutting-edge nonlinear experiments including the low-noise, bright MIR supercontinuum generation, nonlinear optics in gas-filled hollow-core Photonics crystal fibers (PCFs), and high-order harmonic generation in solid state and gases will be conducted.The Fellow with the expertise in the field of ultrafast fiber lasers will be integrated into an international EU team with complimentary expertise on nonlinear optics. The Fellow will be trained in the fast-growing field of MIR ultrafast nonlinear optics, gaining new knowledge on numbers of interdisciplinary techniques, namely: (1) advanced soliton theory, (2) development of high bright MIRSCG in infrared fibers as well as in gas-filled PCF; (3) compression of high-energy MIR pulses in gas-filled PCF and (4) extreme nonlinear optics like HHG with fiber lasers. The supervisory EU team includes the world leading EU experts: Aston Institute of Photonics Technologies (AIPT), Aston University (Prof. Sergei K. Turitsyn); the Fiber Optics, Devices and Nonlinear Effects group at Technical University of Denmark (DTU, prof. Jesper Lægsgaard) and the Lund Laser Centre at Lund University (LU). (Assoc. prof. Cord Arnold and prof. Anne L’Huillier).

Keywords: ultrafast fiber lasers,mid infrared ultrafast nonlinear optics applications,supercontinuum generation,modelling and experiments,high harmonic generation