Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Deciphering the building blocks of rocky planets using JWST spectra of planet forming disks (DISKS-ROCK)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Netherlands
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 2498632.0
EU funding (EUR): 2498632.0
Participants: 1
Project status: SIGNED

The James Webb Space Telescope (JWST) now peers for the first time into the rocky planet birth environments around Solar-type (T Tauri - TT) and Very Low Mass stars (VLMS) with ages of 1-4 Myr. The data shows that disk gas around TT stars is oxygen-rich, while it is carbon-rich around VLMS; yet they formed inside the same molecular cloud. VLMS are the most abundant stars in the galaxy, hosting most rocky exoplanets known to date, making them key targets to search for life. Yet today, it is paramount that we understand what causes this apparent difference, and the implications for the composition of forming planets and their evolution. JWST mid-infrared spectra contain a forest of molecular emissions which carries the complete information (gas and solids) about the planet forming environment in a complex way. The overarching aim of DISKS-ROCK is to thus characterize the current planet birth environments across stellar mass and to constrain disk evolution during the early build-up phase of rocky planets. I will draw from my expertise in thermo-chemical disk modeling, chemistry and mid-infrared spectroscopy to develop a novel, consistent and comprehensive 2D modeling framework to decipher the evolution that led to the apparent differences in gas composition between TT and VLMS. The key to fully exploit JWST data lies in quantifying how disk substructure formation, transport processes from the outer disk, and gas and dust chemical interaction shape the molecular emission spectra of the inner disks. DISKS-ROCK will characterize the current birth environment of planets and constrain disk evolution during the early build-up phase of rocky planets for a statistically relevant sample of ~50 disks. This will establish whether planets around VLMS and TT stars assemble from the same material and follow similar evolution paths. The results of DISKS-ROCK will put our own Earth into the larger galactic context and provide crucial input to future missions searching for life.

Keywords: astrochemistry planet forming disks t tauri stars very low mass stars
IMPROVING THE EFFECTIVENESS AND SAFETY OF EPIGENETIC EDITING IN BRAIN REGENERATION (REGENERAR)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Portugal,Germany,Sweden
Call: EIC Pathfinder Open (HORIZON-EIC-2023-PATHFINDEROPEN-01, 2023)
Start date: 2024-03-01
End date: 2028-02-29
Duration (months): 48.0
Total project cost (EUR): 2943233.75
EU funding (EUR): 2943233.0
Participants: 6
Project status: SIGNED

The central nervous system has a limited capacity for self-repair. Therefore, technologies to replace lost neurons after an injury, including stroke or neurodegenerative diseases, are of great need. The project REGENERAR aims to develop a non-viral delivery formulation up to TRL4 for the delivery of an epigenetic reprogramming formulation to reprogram glial cells into neurons. The in vitro safety and targeting of the formulation will be tested against glial cells and organotypic cortical slice cultures. Several routes of administrations will be tested to enhance the accumulation of the formulation in the brain. In addition, the in vivo safety, elimination, targeting and epigenetic reprogramming will be evaluated. In addition, toxicological studies will be performed in GLP conditions to evaluate both in vivo systemic and local (brain) effects of the formulation. The development of the non-viral formulation will take in account the contributes of key stakeholders in the area of gene editing, health institutions, patient associations, among others. A roadmap will be developed for upscaling innovation to higher TRL´s upon the end of the action.

Keywords: gene editing epigenetic reprogramming non viral delivery systems spatial transcriptomics
Innovative sediment management framework for a SUstainNable DANube black SEa system (SUNDANSE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Ocean, seas and waters
Destination: Ocean, seas and waters
Action type: Innovation actions
Countries involved: Romania,France,Belgium,Israel,Serbia,Estonia,Ukraine,Austria,Ireland,Bulgaria
Call: Danube river basin lighthouse – Demonstration of effective and sustainable management of sediments in the Danube river-Black sea system (HORIZON-MISS-2023-OCEAN-01, 2023)
Start date: 2024-06-03
End date: 2028-06-02
Duration (months): 48.0
Total project cost (EUR): 8984420.45
EU funding (EUR): 8497157.5
Participants: 22
Project status: SIGNED

The Danube River has played a vital role in supporting both human and animal life for centuries. Since the late 19th century, human interventions have significantly altered the natural flow of the river to optimize its utility. These interventions have included actions such as straightening the riverbed, constructing hydropower plants, collecting freshwater, establishing nuclear power plants, engaging in agriculture, and facilitating navigation. The combined effects of climate change and extensive river regulation have led to a significant disruption in the natural balance of sediment in the Danube River, increasing flood risks, altering hydropower production, decreasing navigability of the river, and affecting in biodiversity within the Danube Basin. SUNDANSE will: • carry out a conceptual Driver-Pressure-State-Impact-Response with multiple levels of analysis (catchment level, water body level, etc.) to understand and address environmental issues of the uniqueness of Danube river lighthouse • realize maps for observation of critical points for excessive sedimentation and/or excessive erosion, sediment transport and flow restoration • perform innovative actions of measurements using cutting-edge portable on-vessel equipment prototypes for the direct analysis of microplastics and toxicity • achieve an advance numerical prediction model of sediment transport process in the Danube River basin, to have a comprehensive overview of river dynamics • develop an Innovative Sediment Management Framework for enhanced and sustainable sediment management within the Danube River basin • produce an Action plan and Roadmap for associated regions to upscale demonstrated sustainable and effective solutions for sediment management • fulfil interconnections synergies with DanubeSediment and SIMONA projects and ICDPR initiatives • improve the trans - national and cross - sectorial cooperation, contributing to a better governance in region and to implementation of EU strategi

Keywords: simulation,sedimentation,use case,scaled test,handbook
Monsoon, Upwelling, Silicon and Carbon cycling: climate driven interplays in the Arabian Sea up to the last InTerglacial (MUSiC ArT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France,New Zealand,Switzerland
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2028-08-31
Duration (months): 36.0
Total project cost (EUR): 314329.08
EU funding (EUR): 314329.08
Participants: 4
Project status: SIGNED

In the Arabian Sea, the South West Monsoon (SWM) is active during summer and drives the Somali-Arabian Upwelling System (SAUS). The SAUS brings cold, deep and nutrient-rich water masses to the Indian Ocean’s surface, fuelling siliceous microplankton or silicifiers. Silicifiers (mainly diatoms and radiolarians), are an important component of the soft tissue pump, a biological mechanism that lowers atmospheric CO2 concentrations. Despite the key role of this soft tissue pump in monitoring global climate and the socio-economic impacts of the SWM and SAUS in middle East and Eurasia, little is known about the monsoon, upwelling and soft tissue pump variability in strength relative to past climate and how they may evolve in the future due to global warming. To palliate this problem, MUSiC ArT proposes to use state-of-the-art technologies and methods to deconvolute the influence of climate on the SAUS and SWM intensity and associated-impacts on siliceous productivity over the last 150,000 years, covering the last interglacial period. The project aims to carry out innovative micropalaeontological and geochemical analyses on two sediment cores of the collections available at the Museum National d’Histoire Naturelle (MNHN, Paris, France). During the outgoing phase at GNS Science (New-Zealand), Artificial Intelligence and conventional microscopy will be used to generate census radiolarian and diatom counts. During a secondment at the University of Lausanne (Switzerland), isotopic ratios of 230Th and 232Th will be measured. For the return phase at the MNHN, diatom counts and high-quality imagery on microfossils will be completed and the isotope ratio of Silicon (δ30Si) and the Ge/Si ratio will be analysed on handpicked monospecific radiolarian and monogenus diatom samples. With this multidisciplinary approach, MUSiC ArT aims to couple AI, micropaleontology and geochemistry, advancing the Primary Investigator (PI)’s career by developing his unique researcher profile.

Keywords: indian ocean,upwelling,soft tissue pump,radiolarians,diatoms,taxonomy,microscopy,artificial intelligence,geochemistry,isotopes,mass spectrometry,biogeochemical cycles,th,si,ge,c
Autonomous Scanning Probe Microscopy for Life Sciences and Medicine powered by Artificial Intelligence (SPM4.0)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Sweden,France,Germany,Italy,Czechia,United Kingdom,Poland
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 4217380.46
EU funding (EUR): 3886545.6
Participants: 22
Project status: SIGNED

Artificial Intelligence is pushing forward the Industrial Revolution 4.0, which is transforming many areas of Society, including Science and Technology. Nanoscopy, a recognized pillar of the research and manufacture of Nanotechnology-based products, is among the areas that more quickly is adopting Artificial Intelligence. Machine learning algorithms are being developed and integrated in microscopes for its autonomous operation and in software toolboxes for the automatic analysis of large volumes of microscopy data. Scanning Probe Microscopy is particularly active in this integration with a special focus in the Life Sciences and Medical fields. Scanning probe microscopes powered by machine learning are expected to enable the autonomous and label-free nanoscale structural and functional (mechanical and electric) imaging of living cells and functional biomolecules in their native conditions, something never achieved in nanoscopic imaging. The objective of the SPM4.0 Doctoral Network is to train a new generation of researchers in the science and technology of autonomous Scanning Probe Microscopes powered by Artificial Intelligence for applications in the Life Science and Medical fields. The researchers of the network will acquire a state-of-the-art multidisciplinary scientific training in advanced scanning probe microscopy and machine learning and in their biological and medical applications. In addition, they will receive training on complementary and transferable skills to increase their employability perspectives and to qualify them to access to responsibility job positions in the private and public sectors. The final aim is to promote the wide adoption of SPM4.0 technologies in public and private research centers and in industrial and metrology institutions and to explore new horizons in the Life Sciences and Medical sectors regarding label-free nanoscopic cell imaging, illness diagnosis, or drug nanocarrier development, consolidating Europe as world leader.

Keywords: atomic force microscopy,scanning probe microscopy,autonomous devices,nanomechanical and nanoelectrical mapping,deep learning,nanomedicine,functional imaging,standardization,cell imaging
Dried fruits as a source of Prebiotic Oligosaccharides and Soluble dietary fiber: The case study of fig. (PrOSFig)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Portugal
Call: ERA Fellowships (HORIZON-WIDERA-2023-TALENTS-02, 2023)
Start date: 2025-02-01
End date: 2027-01-31
Duration (months): 24.0
Total project cost (EUR): 156778.56
EU funding (EUR): 156778.56
Participants: 3
Project status: SIGNED

Health diets require diversification of nutrients, supporting and promoting the traditional food products while keep finding new ways to their safeguard. Figs are nutritious and delicious products endowed with many health-benefiting nutrients. Drying contributes to widen their availability, diversify trade, and promote their nutritive value. Recent research trends show that oligosaccharides (OS) and soluble polysaccharides non-digestible by human gut enzymes are of great interest for their health benefits and natural nutraceutical value. Although dried figs nutritional quality has been well studied, there is a lack of knowledge on the matching of the OS and soluble dietary fiber (SDF) structural features and their potential health dietary benefits. PrOSFig project aims at valorizing dried figs OS as prebiotics and polysaccharides as SDF. As an MSCA fellow, I propose to study at UAveiro the (i) drying processing, consumer perception and conservation of figs (ii) extraction and chemical characterization of dried figs OS and SDF. This will allow to perform a secondment at UPorto to (iii) monitor the bioavailability and bioaccessibility of the OS and SDF and their interactions with fig polyphenols, and a second secondment at UMinho to (iv) carry out in vitro assessment of prebiotic properties. This interdisciplinary approach in a relevant food research topic, draws a unique skill set and state-of-the-art in four different but complementary fields: (1) drying technology for producing healthy foods, (2) consumer acceptability of traditional dried fruits (3) food biochemistry via the application of spectroscopic techniques as tools for OS and SDF characterization, and (4) bio-engineering for evaluating the physiological aspects of OS and SDF related with gut microbiota. The integration in these Universities dissemination and communication programs, as well as in their training activities, will support me to develop my career.

Keywords: carbohydrate,oligosaccharide,polysaccharide,soluble dietary fiber,prebiotic,polyphenol interaction,in vitro gastrointestinal digestion
HEALTHY ENVIRONMENTAL-FRIENDLY AND RESILIENT FARM TO FORK (HE-FARM)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Spain,France,Italy,Poland,Hungary,Romania
Call: Enhancing biosecurity in terrestrial livestock production (HORIZON-CL6-2022-FARM2FORK-01, 2022)
Start date: 2022-11-01
End date: 2026-02-28
Duration (months): 40.0
Total project cost (EUR): 4999859.0
EU funding (EUR): 4999859.0
Participants: 15
Project status: SIGNED

In spite of the huge number of pathogens and diseases, the number of “transmission channels” or “transport routes” for microorganisms to enter in a farm or any other Farm2Fork facility is indeed limited to just nine. Tracing or monitoring transport of a single or a few microorganisms using a particular channel will provide valuable information on the channel itself and therefore on the transport effectiveness for the whole set of microorganisms using that particular channel. HE-FARM will develop and validate a methodology -based on experimental assays and tests in lab & operational env- to assess and predict transport-channel resolved biosecurity and simultaneously increase maturity of several disruptive novel techs. A software/APP will be created to help with these procedures and proposed as a draft for a future EN standard. Prototypes of novel technologies for biosecurity will additionally be developed and validated in operational environment -including extensive and intensive cow, pig, chicken, turkey, sheep and snail farms, a slaughter and meat preparation plant and trucks: Fast Integrated air-borne virus smart detector (PRRS and Avian Flue but easily extendable to other virus with an enormous like African Swine Fever whose early detection in air in minutes will have an enormous impact) Sanitization by low-toxicity biocides & dynamic aggregation. Low-toxicity insecticides & repellents & dynamic aggregation application & Env-Friendly Insect and Arachnids barrier and prevention techs. Rapid Vehicle decon. station. Biosecure & Env-Friendly Hall & Heat Venting and Cooling. Portable Low-cost test-device for fast measuring microbiological metabolism. Cold plasma farm water sanitization. Usage and training procedures and manuals & assessment of performance method. Finally at least other 3 biosecure techs externally provided selected in an open call will be experimentally tested. Comm. & dissemination include liaising with authorities like EFSA and OIE.
Communities and Artistic Participation in Hybrid Environment (CAPHE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Poland,Greece,Italy,Portugal,United Kingdom,Kenya
Call: MSCA Staff Exchanges 2021 (HORIZON-MSCA-2021-SE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 1585028.57
EU funding (EUR): 1449000.0
Participants: 10
Project status: SIGNED

The aim of the project is to investigate and perform the possibility of elaboration of an enhanced model of interaction and somatic participation between artists and communities, coming from different cultural backgrounds, both traditional and virtual ones in hybrid environment, including physical, and virtual layers. By this mean we will develop the concept of VR Participation, building the integrated framework for VR-mediated consensus and community in a form of an aesthetic dialogue, geared toward layering and investigating aesthetic experiences through VR technology. The project’s physical mobilities will be directed towards sharing knowledge and proficiency in different fields such as humanities, arts, technology, and education, focused on the research on communities, arts, and participation in contemporary, digital time in countries involved in the project: Poland, Portugal, Italy, Greece, and Kenya. Apart of activities realized during the mobilities: workshops, trainings, field research and interviews, the cooperation between partners in the CAPHE project will be continued during the whole project in the virtual space, online. This will be realized with use of modes of telepresence, Augmented Reality (AR) and Virtual Reality (VR) technologies such as the AltspaceVR platform. The project’s team will be engaged and will operate in experimental, hybrid environment to stimulate and research the process of social-artistic interaction. Our process will engage artists, communities, and researchers from six countries, and on two continents (Europe and Africa). The countries are located on the South of Europe: Portugal, Italy, and Greece, and North and South from this line: Poland and Kenya. This gives a broad spectrum of contexts.

Keywords: communities,art,participation,hybrid environment,vr,augmented reality,education,aesthetics,avatars,online,immersion,nft,environment,
Growing online - how to protect our children in the digital world? (GUARDIAN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Poland,Czechia,United Kingdom,Kenya
Call: MSCA Staff Exchanges 2023 (HORIZON-MSCA-2023-SE-01, 2023)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 547400.0
EU funding (EUR): 547400.0
Participants: 5
Project status: SIGNED

Digital technologies have become an important part of children's daily lives, regardless of cultural and geographical context. This is often due to the actions of parents who notoriously share information about their children on the Internet. Social media can today be considered a "modern baby album", where by sharing photos of their children, parents present themselves as good parents, giving birth to adorable babies, with a sense of humor and evidence of milestones achieved - all indicators family health and happiness. Very often children are not aware that thanks to their parents they have become celebrities on social media. This parental behavior, known as sharenting, is becoming more and more common around the world putting children at risk: loss of privacy (children do not have a say in what information is shared about them online, this digital footprint can be difficult to control later in life), identity theft (personal information can be used for identity theft, impacting children's security), exploitation (images and information can be used for commercial purposes), cyberbullying and harassment. The main goal of GUARDIAN is to investigate the extent and dimensions of sharenting in Europe and East Africa from intercultural perspectives in order to provide guidance and recommendations on the measures required to respect and protect children’s rights in the digital world. The project will promote the rights of the child and raise awareness of the society about risks and challenges experienced by children in the digital environment and help them to navigate the online world responsibly. The project will be implemented by academic institutions from 4 countries: Poland, Czechia, United Kingdom and, Kenya. The transfer of knowledge and common reaserch will contribute not only to the achievement of the project goal, but also to the realisation of the potential of participants, allowing them to acquire new skills and professional qualifications.

Keywords: sharenting,children s rights,internet,online users behavior