Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Ultra-secure data storage - and long-term preservation of digital and analogue data (Piql-GO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Norway
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2018-04-01
End date: 2021-03-31
Duration (months): 36.0
Total project cost (EUR): 2848500.0
EU funding (EUR): 1993950.0
Participants: 1
Project status: CLOSED

The overall objective of Piql-GO is to upscale, pilot, and commercialise our disruptive and migration-free Piql System & Services for ultra-secure and long-term preservation of digital and analogue data, guaranteeing data authenticity and integrity for 500+ years. We have converted photosensitive film into a self-contained and migration free digital preservation medium (‘bits-on-film’), stored as a very high resolution 2D QR-codes, with a longevity of 500+ years, all integrated into a standard IT environment. Piql is the only solution allowing to store both, visual and digital information. In the Piql-GO Phase 2 project we will address and implement the findings of our SME Phase 1 (GA#674422) to enable rapid and successful commercialisation of our Services. We have outlined a series of specific objectives (grouped in 3 categories) and achieving them will bring us to a wide global market uptake: 1) Technology maturation objectives will optimise Piql System functionalities prior to piloting by end-clients. Objective to raise the TRL of our technology from its current TRL7 to 8 (WP1). 2) Pilot & validation objectives to demonstrate and validate the commercial potential of Piql Services in real-operation environment supervised by 7 potential end-clients (i.e. The Vatican Library & Walt Disney) representing 6 targeted market segments across 6 target countries. The piloting activities will elevate Piql System from TRL8 to 9 (WP2). 3) Market maturation, communication and innovation management objectives enabling us to successfully bring Piql Services to the market and reach sales traction beyond Phase 2 (WP4-6). Through Piql-GO we will boost our growth - quantified as accrued revenues exceeding €183.9m 5-year post-project with accrued net earn. of more than €122.8m and job creation of at least 90 FTEs at Piql and 245 in our value chain. Finally, we will enable cost savings for end-clients equal to accrued NPV of €1.37bn on 15 years and €3.38bn on 100 years.

Keywords: long term preservation,ultra secure,archiving,migration free,digital storage,data storage,digital preservation,cultural heritage,offline,true worm,photosensitive film
A personal electric mobility snow vehicle (MoonBikes)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-06-01
End date: 2019-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Founded by a former Dassault Aviation engineer, MoonBikes is born from a simple fact: snowmobiles are big fat polluting machines, noisy, smelly, difficult to drive and expensive. While their use in snow resorts and remote areas would bring significant advantages (limit the use of cars, solve accessibility problems, introduce new fun uses for all without pollution or noise), their democratization requires a new approach to reduce its cost, noise, size and pollution level. To revolutionize snow-mobility, MoonBikes conceptualized the snowmobile experience and created an electric, ultralight & silent snowmobile, foldable to ease its transport, simple to use and affordable. MoonBikes are 4x lighter & 2x less expensive than regular snowmobiles, and are 100% green (no emissions). MoonBikes targets Ski resorts (utility vehicle, individual mobility), Snowmobile rentals (MoonBikes Parks at the bottom of ski slopes - like a karting circuit), and Individuals living in snowy environments. MoonBikes will tap into an existing market amounting to 37 000 sales/year, and open up a new market representing an additional 750 000 accessible users. Several major French ski resorts have shown a strong interest in MoonBikes, and trials will take place this winter in these resorts. MoonBikes targets to grab 10% of this new market with its affordable & simple product, making snowmobile an accessible commodity for all. MoonBikes’ solution is currently at TRL6, with 2 demonstrators developed and tested in real conditions and in labs (more than 100 hours of testing), two new prototypes under development, and 2 patents pending. Our goal is to deliver the first MoonBikes to pilot stations in December 2019. Created in 2017 and Incubated at Station F & the Arts et Métiers incubator, and supported by the “Cluster Montagne” (Mountain Cluster), MoonBikes employs 4 people.

Keywords: personal electric mobility,snow mobility,snowmobile
Functional Interrogation of Non-coding DNA Sequences in leukemia development and drug resistance (FIND-seq)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Austria
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-03-01
End date: 2026-02-28
Duration (months): 60.0
Total project cost (EUR): 1784000.0
EU funding (EUR): 1784000.0
Participants: 2
Project status: SIGNED

Functional non-coding regions of the genome play a fundamental role in gene expression and are enriched for disease associated variants. Perturbation of non-coding regions harbouring disease-associated variants is now the rationale of ongoing clinical trials (e.g. NCT03432364), highlighting the translational potential of basic research in the non-coding space. However, our ability to systematically identify disease-associated functional elements in the non-coding genome, understand its grammar, and subsequently develop new therapies is limited. CRISPR-based pooled screens targeting non-coding elements in situ have been successful in uncovering complex gene regulatory architecture in a variety of biological systems. However, these approaches are limited to a few loci, lack of direct genotype-phenotype correlation, and do not target large chromatin structures that determine gene expression programs. To overcome these limitations, I propose a multi-scale approach platform that is generalizable to different cell types and phenotypes. Under this proposal, I will focus on the role of non-coding sequences in the context of blood malignancies. I will investigate non-coding sequences whose change in chromatin state (activation or repression) is associated with drug resistance in Chronic Myelogenous Leukemia (CML). I will study alterations in the chromatin structure (i.e. at chromatin loops or topologically associated domains) that are causal to imatinib resistance in CML. Finally, to learn enhancer grammar and mechanistically link non-coding variants to disease, I will focus on non-coding sequence variation in leukemia and dissect non-coding sequences at base pair resolution using dense mutagenesis coupled with long-reads sequencing. A deeper understanding of the non-coding regulatory architecture in diseases will provide the basis for development of innovative therapies targeting the non-coding genome.
Biological signal processing via multisite phosphorylation networks (Phosphoprocessors)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Estonia
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-05-01
End date: 2020-10-31
Duration (months): 66.0
Total project cost (EUR): 1999288.67
EU funding (EUR): 1999288.67
Participants: 1
Project status: CLOSED

Multisite phosphorylation of proteins is a powerful signal processing mechanism playing crucial roles in cell division and differentiation as well as in disease. Our goal in this application is to elucidate the molecular basis of this important mechanism. We recently demonstrated a novel phenomenon of multisite phosphorylation in cell cycle regulation. We showed that cyclin-dependent kinase (CDK)-dependent multisite phosphorylation of a crucial substrate is performed semiprocessively in the N-to-C terminal direction along the disordered protein. The process is controlled by key parameters including the distance between phosphorylation sites, the distribution of serines and threonines in sites, and the position of docking motifs. According to our model, linear patterns of phosphorylation networks along the disordered protein segments determine the net phosphorylation rate of the protein. This concept provides a new interpretation of CDK signal processing, and it can explain how the temporal order of cell cycle events is achieved. The goals of this study are: 1) We will seek proof of the model by rewiring the patterns of budding yeast Cdk1 multisite networks according to the rules we have identified, so to change the order of cell cycle events. Next, we will restore the order by alternative wiring of the same switches; 2) To apply the proposed model in the context of different kinases and complex substrate arrangements, we will study the Cdk1-dependent multisite phosphorylation of kinetochore components, to understand the phospho-regulation of kinetochore formation, microtubule attachment and error correction; 3) We will apply multisite phosphorylation to design circuits for synthetic biology. A toolbox of synthetic parts based on multisite phosphorylation would revolutionize the field since the fast time scales and wide combinatorial possibilities.
The Psychological Benefits of Interacting with Nature (PSYNAT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-04-01
End date: 2023-03-31
Duration (months): 24.0
Total project cost (EUR): 178320.0
EU funding (EUR): 178320.0
Participants: 1
Project status: CLOSED

There is increasing scientific evidence that interacting with nature improves cognition and boosts feelings of emotional well-being. However, as more of the world is being developed, people's exposure to nature is being threatened. With that comes potentially harmful effects on human cognition and mental health. The Attention Restoration Theory suggests that nature is beneficial because it captures bottom-up attention moderately - enough to be interesting and not boring - giving the attention system a chance to restore itself, improving cognition and mood. However, the existing research has not clearly defined how or why nature captures attention “moderately”. Theories of aesthetic pleasure begin to answer this question by introducing the idea of disfluency reduction. The process of disfluency reduction leads to an aesthetic experience. Too much or too little disfluency or complexity within a scene results in feelings of confusion or boredom, respectively. Here, I aim to investigate the psychological mechanisms that account for the cognitive and emotional benefits of interacting with nature by integrating the attention restoration research with the aesthetic pleasure research. Specific objectives are: (1) assessing the behavioural and neural outcomes of immersion in nature using virtual reality combined with eye tracking and electroencephalography (EEG); (2) assessing the outcomes of isolation from nature using deep convolutional neural networks and machine learning; and (3) assessing the visual features that account for the above outcomes. Through understanding the psychological mechanisms underlying the benefits of nature exposure, we will be able to fully harness nature’s benefits and to forecast the negative impacts that further urbanization and indoor confinement may have on well-being. We can then use this knowledge to incorporate the important elements of nature in the design of new urban and indoor spaces, in order to minimize the negative impacts.

Keywords: cognition,emotion,attention,visual aesthetics,scene perception,virtual reality,eye tracking,nature
Mapping Skills and Competencies; Providing Access to Knowledge, Tools and Platforms; and Strengthening, Disseminating and Exploiting Success Outcomes for a Skilled Transatlantic eHealth Workforce (EUUSEHEALTHWORK)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Health care provision and integrated care
Action type: Coordination and support actions
Countries involved: Germany,Germany,Germany,Finland,Belgium,United States
Call: Healthcare Workforce IT skills (H2020-SC1-2016-CNECT, 2016)
Start date: 2016-09-01
End date: 2018-05-31
Duration (months): 21.0
Total project cost (EUR): 497250.0
EU funding (EUR): 497250.0
Participants: 8
Project status: CLOSED

The EU-US eHealth Workforce Development Consortium has an overall goal of mapping, quantifying and projecting the need, supply and demand for workforce skills and competences, utilising these results to further develop IT skills and training programmes for the healthcare workforce. This work is a continuation and further development of the EU-US collaboration under the EU-US MoU eHealth Roadmap, leveraging the work this group has developed to date, including the HITCOMP Tool and Repository. Additionally, we hope to build upon that work to include intersecting it with foundational education and training methods and materials in eHealth. We will continue analysing the needs, trends and approaches to improve the health IT workforce. Finally, we will provide an interactive web platform in which end-users, educators, governments and industry can: communicate; exchange information; provide and locate opportunities for training, skills development and employment opportunities; and increase knowledge related to the eHealth, health information technology, and health informatics disciplines.

Keywords: hitcomp,career,progression,competencies,didactics,educators,clinicians,providers,end user,students,himss,tiger,informatics
The Continuation of Politics with Other Means: War and Protest, 1914-2011 (COPWOM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-03-31
Duration (months): 18.0
Total project cost (EUR): 119595.6
EU funding (EUR): 119595.6
Participants: 1
Project status: CLOSED

This project looks at the political means employed by those who, for various reasons, resorted to protest during times of war in the period from the First World War to the Iraq War. In most cases, the challengers embraced alternative means of political articulation due to the established channels of political decision making being controlled by the supporters of the war in question. Case studies illuminate the manifestations of war-time protest in different wars including both the well-known and some of the "forgotten wars": First World War, Spanish Civil War, Second World War, Korean War, Vietnam War, Soviet War in Afghanistan, Falklands War, Kosovo War and Iraq War. The project pursues the objective to articulate the relationship between war and protest and to develop further the debate surrounding war as a channel of cultural, social and political change. It will advance research into the comparative dimension of war-time protest by embedding this investigation in an analytical framework focused on the methods and questions of historical enquiry into social movements, and to give further specificity to the debate on processes of politicisation and depoliticisation with particular focus on the variety of motivations that drove war-time protest beyond just pacifism. This analysis combines methods from the history of protest and social movements, the history of war, the history of political thought as well as film and visual studies. The project provides conceptual tools and evidence on the pre-history of present-day protests, e.g. against U.S. unilateralism in Iraq. Via a number of publications and engagement events, especially in conjunction with public film screenings, it will create impact by intervening in current debates about the repercussions of global warfare and by furthering public awareness of the crucial historical role of war-time protest in the European political heritage.

Keywords: protest,social movements,violence,20th century,21st century,anti war film
Electric axle for hybrid / electric commercial vehicles (ELECTRIC_AXLE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Hungary
Call: Small business innovation research for Transport (H2020-SMEINST-1-2014, 2014)
Start date: 2015-05-01
End date: 2015-09-30
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Silex’s goal with the project is to increase its turnover, profit and size by innovation, in order to become a medium size enterprise. During the project an 8,5 -9 tons axle will be developed with integrated in-wheel electric motors, for electric/hybrid commercial vehicles (city buses, small trucks distributing products and fork lifts). Currently there are no commercially available axles designed for these vehicles, which is the novelty of the project. Vehicles using available axles, designed for combustion engines are heavier; consume more energy then necessary and contain components (propeller shaft, differential), which can be omitted in another architecture. Using the in-wheel motors ABS, ASR, retarder functions will be solved electronically. The axle will be 30% lighter then available ones, reducing vehicle’s energy consumption by 6-8%. Patent search has shown that the key IPs of the project are currently not patented. Technical goal of the project is to develop, test and verify the axle and build it into a test vehicle to start field tests. Systems, based on the new axle will be 2-2500 € cheaper then existing solutions. Lower price plus energy saving, i.e. lower operating costs are the two key sales arguments, which meet market demands. According to our preliminary market analyses, assuming 10% market share in the 3 market segments mentioned above, 1500-2000 axles can be sold p.a., which means 15-20 million € turnover and 2,5 – 3,5 million € profit. In Phase 1 a detailed Feasibility study will be elaborated, including technical details, project schedule, market analyses and strategy in order to co-fund Phase 2, what we estimate to 650-700 k€ as total project cost. Feasibility study will conclude to a business plan for different market scenarios. Investment will be evaluated by payback time and ROI. Business plan will comply with accounting standards. The project results a small contribution to increase energy efficiency and improve European competitiveness.

Keywords: electric axle,in wheel motor,hybrid,full electric commercial vehicles,energy efficiency,electric,drives,integrated vehicle control
Tuning both the photoluminescence and conductive properties of new COP materials (Tuning COPs)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-10-15
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

The main goal of this proposed project is the synthesis of new hybrid π-conjugated polymers for industrial use, which conductive and optical properties could be fine tuneable by the proper anionic metallacarboranes as doping agents. To achieve our goals two directions were chosen. In the first part we would like to investigate the effect of different boron clusters ([Co(C2B9HnX11-n)2]- X=Cl, Br, I) as doping agents on the conductive and photoluminescence properties of the poly(3,4-ethylenedioxythiophene) (PEDOT). Preliminary results suggest that the earlier used [Co(C2B9H11)2]- doping anion is redoxactive, thus it has a big influence on the formation and the properties of the polymer. Our expectation is that the halogen analogues ([Co(C2B9HnX11-n)2]-=Cl, Br, I) cover a wide range of redoxpotential, thus we can easily modify the properties of the new materials. During the second part we would like to tune both the conductive and photoluminescence properties of the poly(p-phenylene vinylene) (PPV). For this purpose different co-polymer planed to synthetized, which containing different amount of non-doped and self-doped monomer units. (In case of the self-doped polymer the doping anion is covalently linked to the monomer unit). We expect that the ratio of the non-doped and the self-doped has a strong influence both the conductive and photoluminescent properties, moreover the two different properties will be altered by the inclusion of functional side groups.

Keywords: conductive organic polymers,doping agents,photoluminescence material