Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Innovative robotic sorting technology to reduce hazardous wastes (RED LINE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2021-07-01
End date: 2024-06-30
Duration (months): 36.0
Total project cost (EUR): 3303187.5
EU funding (EUR): 2312231.25
Participants: 1
Project status: SIGNED

4,7 million m3 of solid nuclear waste are piling up in silos worldwide, awaiting final disposal. By 2050, they will be 11,4 million m3. Regulation is pushing for their reconditioning. However, only a few waste recovery programs are running today, where each piece of waste is sorted by human teleoperators. It takes 10 years and millions of euro to sort a 500m3 silo, with risks of error every ten pieces, radiation exposure, and contamination of the environment. This is poorly effective. These heterogeneous wastes are so instable that automated sorting is deemed impossible. With this project, SILÉANE will scale up its autonomous waste sorting robotic system, currently applied to civil waste-producing industries, to clean up more than half of the past century’s nuclear waste production and reduce the number of future hazardous wastes generated by this industry and other civil applications. The project will deliver a full-scale demonstrator of an integrated robotic system that will sort and segregate these wastes automatically and error-free into optimised containers. They will be extracted one by one before crossing a scanning “red line” emitted by the system. Their nature will be accurately characterized (radioactivity emission, chemical composition) with all data recorded in inventories. This process is 2,5 times faster than teleoperation, costs 3 times less and is safe, leaving less waste behind. 80% of the waste will go for reconditioning and recycling (versus 30% today). During feasibility phase, it showed a 99,5% accuracy rate on 540 tons of waste. SILEANE will grab the lead in the global nuclear waste sorting market (30% market share by 2030) and improve its market shares in the civil waste market, where the trend for automation is booming as well. Finally, SILÉANE will scale-up its organizational structure to address an increasing number of heterogeneous waste-producing industries worldwide. This project will raise the bar for SILÉANE at the corporate level.

Keywords: waste management,nuclear waste,hazardous waste,civil waste,artificial intelligence,waste sorting,circular economy
The cryptic path of tumor-microenvironment interactions in prostate cancer (STOPCa)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2020-01-20
Duration (months): 24.0
Total project cost (EUR): 175419.6
EU funding (EUR): 175419.6
Participants: 1
Project status: CLOSED

In the developed countries, prostate cancer is the second leading cause of cancer-associated death in men, with a predicted rate of 10.9/100.000 men in Europe in 2016. Mortality results when prostate cancer has spread to other organs (metastasis, particularly to the bone). Prostate cancer prognosis and follow-up is mainly performed with routine blood test (prostate specific antigen levels). However, the low/high risk of metastasis for individual patients cannot always be accurately assessed due to tumor heterogeneity and differential rate of tumor progression. Thus, a more thorough understanding of the metastatic processes is needed. Complex molecular interactions and cellular processes between the cancer (stem) cells and the surrounding tissue microenvironment (supportive stroma) are required for tumor growth and metastasis. Cancer cells hijack the normal microenvironment to orchestrate metastatic events and acquisition of resistance to drug treatments. To increase our understanding of the metastatic mechanisms we sought to identify and modulate the molecular properties of aggressive tumor cells and the reciprocal supportive stroma in unique xenograft models and eventually assess the prognostic value of the identified parameters. We propose to investigate the following objectives: 1) identify the molecular signature of tumor and supportive stroma in metastatic patient-derived xenografts 2) elucidate the molecular mechanisms of the tumor- supportive stroma 3) determine their prognostic value in clinical blood samples as predictors of disease progression and metastasis risk. Understanding the mechanisms of prostate cancer (re)initiation will provide the foundation for proper prognostic tool development for the identification of high risk patient groups.

Keywords: prostate tumor microenvironment transcriptomics patient derived xenografts metastasis tissue compartment transcriptional profiling
Privacy and Utility Allied (HYPATIA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: France
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-10-01
End date: 2024-09-30
Duration (months): 60.0
Total project cost (EUR): 2223779.0
EU funding (EUR): 2223779.0
Participants: 1
Project status: SIGNED

With the ever-increasing use of internet-connected devices, such as computers, smart grids, IoT appliances and GPS-enabled equipments, personal data are collected in larger and larger amounts, and then stored and manipulated for the most diverse purposes. Undeniably, the big-data technology provides enormous benefits to industry, individuals and society, ranging from improving business strategies and boosting quality of service to enhancing scientific progress. On the other hand, however, the collection and manipulation of personal data raises alarming privacy issues. Both the experts and the population at large are becoming increasingly aware of the risks, due to the repeated cases of violations and leaks that keep hitting the headlines. The objective of this project is to develop the theoretical foundations, methods and tools to protect the privacy of the individuals while letting their data to be collected and used for statistical purposes. We aim in particular at developing mechanisms that: (1) can be applied and controlled directly by the user, thus avoiding the need of a trusted party, (2) are robust with respect to combination of information from different sources, and (3) provide an optimal trade-off between privacy and utility. We intend to pursue these goals by developing a new framework for privacy based on the addition of controlled noise to individual data, and associated methods to recover the useful statistical information, and to protect the quality of service.

Keywords: local differential privacy,convex optimization,information theory
Smart, User-friendly, Interactive, Tactual, Cognition-Enhancer that Yields Extended Sensosphere - Appropriating sensor technologies, machine learning, gamification and smart haptic interfaces (SUITCEYES)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Greece,Poland,Sweden,France,Netherlands,Netherlands,United Kingdom
Call: Interfaces for accessibility (H2020-ICT-2017-1, 2017)
Start date: 2018-01-01
End date: 2021-06-30
Duration (months): 42.0
Total project cost (EUR): 2359963.0
EU funding (EUR): 2359963.0
Participants: 8
Project status: CLOSED

Useful ICT innovations are continuously developed improving the quality of life for many people. However, such solutions do not typically included people with severe dual vision and hearing impairments, and at times also coupled with cognitive disability. Deafblindness is a grave condition. Though, rare at birth, it can be acquired due to different causes. There is an estimated 2.5 M deafblind persons in the EU. Limited communication is a major problem for this group; something that will be addressed by SUITCEYES in a novel way. Benefits are not limited to this group; rather the solution will scale to other areas. SUITCEYES proposes a new, intelligent, flexible and expandable mode of haptic communication via soft interfaces. Based on user needs and informed by disability studies, the project combines smart textiles, sensors, semantic technologies, image processing, face and object recognition, machine learning, and gamification. It will address three challenges: perception of the environment; communication and exchange of semantic content; learning and joyful life experiences. SUITCEYES will extract and map the inner structure of high-dimensional, environmental and linguistic clues to low-dimensional spaces, which then translate into haptic signals. It will also utilize image processing, mapping environmental data to be used for enriched semantic reasoning. SUITCEYES’ intelligent haptic interface will help the users to learn activation patterns by a new medium. With this interface, users will be able to take more active part in society, improving possibilities for inclusion in social life and employment. The solution will be developed in a user-centred iterative design process, with frequent evaluations and optimizations. The users’ learning experiences will be enriched through gamification and mediated social interactions. The proposed solution will take into account the potential differences in levels of impairments and user capabilities and adapt accordingly.
Rural regeneration through systemic heritage-led strategies (RURITAGE)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Cultural heritage
Action type: Innovation actions
Countries involved: Iceland,Austria,Germany,Spain,Ireland,Italy,Italy,Italy,Italy,Spain,Germany,Spain,Italy,Spain,Italy,Greece,Romania,Slovenia,Colombia,Norway,Türkiye,Finland,Greece,Hungary,Norway,Türkiye,Slovenia,Poland,France,France,France,Netherlands,United Kingdom,United Kingdom,Chile
Call: Cultural heritage as a driver for sustainable growth (H2020-SC5-2017-TwoStage, 2017)
Start date: 2018-06-01
End date: 2022-08-31
Duration (months): 51.0
Total project cost (EUR): 10276187.5
EU funding (EUR): 9975651.25
Participants: 40
Project status: CLOSED

European rural areas embody outstanding examples of Cultural and Natural Heritage (CNH) that need not only to be safeguarded, but also promoted as a driver for competitiveness, sustainable and inclusive growth and development. RURITAGE establishes a new heritage-led rural regeneration paradigm able to turn rural areas in sustainable development demonstration laboratories, through the enhancement of their unique CNH potential. RURITAGE has identified 6 Systemic Innovation Areas (pilgrimages; sustainable local food production; migration; art and festivals; resilience; and integrated landscape management) which, integrated with cross-cutting themes, showcase heritage potential as a powerful engine for economic, social and environmental development of rural areas. The knowledge built in 14 Role Models (RMs) and digested within the project, will be transferred to 6 Replicators (Rs) across Europe. Through a multilevel and multidirectional process of knowledge transfer, RMs will mentor and support the Replicators in the development and implementation of their strategies and, at the same time, will further increase their knowledge and capacities. A robust monitoring system will assist this process. Local Rural Heritage Hubs, gathering stakeholders and civil society, will be settled in Rs to work as living labs where heritage-led rural regeneration strategies will be co-created and implemented, while in RMs they will reinforce the ownership of CNH. Both RMs and Rs will also benefit of the RURITAGE Resources Ecosystem, a set of tools including, among others, a rural landscape mapping tool (RURITAGE Atlas) and a Replication Toolbox within an online and interoperable platform. These tools will foster knowledge building, providing evidence and supporting replication and up-scaling activities of the implemented heritage-led regeneration strategies and plans, contributing to mainstream heritage in Regional, National, European and global policies.

Keywords: heritage led strategy,rural regeneration,systemic innovation areas,resilience,food production,pilgrimage,migration,landscape management,artandfestival,rural heritage hub,rural atlas,onlinedss
QUANTIFYING THE IMPACT OF TRANSPORT INFRASTRUCTURES: NETWORK ANALYSIS APPLIED TO THE DIACHRONICALLY STUDY OF THE IBERIAN PENINSULA (From Roman Times to XIXth Century) (Mercator-e)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Portugal
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-10-01
End date: 2018-09-30
Duration (months): 24.0
Total project cost (EUR): 160635.6
EU funding (EUR): 160635.6
Participants: 2
Project status: CLOSED

The impact of the transport infrastructures in the development of countries and territories is one of the most current topics in the European policies. The Mercator-e project is designed to analyse the diachronic social, political and economical repercussions of the transport infrastructures during several periods of the Iberian Peninsula. An integrated approach joining multi-proxy analysis (SNA applied to the network centrality, TNA to analyse transport costs & times, demography studies) and the study of archaeo-historical sources will be applied. Analysing the transport communication networks in various time scopes will offer to the academic society new quantified data about the infrastructures morphology and their impact in the political and economical evolution of these territories. Historically, the Iberian Peninsula has had periods with very different political ideologies about the role and needs of infrastructure that will be analysed in this project: 1) The Roman era, 2) The Middle Ages, 3) the Modern Era, and 4) The XIXth Century and the emergence of the railroad. This project offers a new approach to the study and knowledge of the historical infrastructures. From the use of the Network Analysis to study the infrastructures, a set of completely new data could be generated to understand and visualise the transport evolution and the evolution of the territorial configuration. This project will provide a breakthrough in the analysis of transport in big territories. The high digitalisation detail and the diachronic study will offer outstanding results. The Mercator-e methodology will take into account elements such as highly digitised communication networks, historical vehicle characteristics, changes in means of transport or the topography to make more complex and real calculations. Mercator-e will provide a new perspective on ways to quantify Historical Trade and Transport and will place this research into the international research circles of this field.

Keywords: quantifying transport,infrastructures,network analysis,transport networks,history of transport,economy,transport costs,urban connectivity
Study of the interplay between CRISPR interference and DNA repair pathways towards the development of novel CRISPR tools (CRISPAIR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: France
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-03-01
End date: 2022-08-31
Duration (months): 78.0
Total project cost (EUR): 1499763.0
EU funding (EUR): 1499763.0
Participants: 1
Project status: CLOSED

CRISPR-Cas loci are the adaptive immune system of archaea and bacteria. They can capture pieces of invading DNA and use this information to degrade target DNA through the action of RNA-guided nucleases. The consequences of DNA cleavage by Cas nucleases, i.e. how breaks are processed and whether they can be repaired, remains to be investigated. A better understanding of the interplay between DNA repair and CRISPR-Cas is critical both to shed light on the evolution and biology of these fascinating systems and for the development of biotechnological tools based on Cas nucleases. CRISPR systems have indeed become a popular tool to edit Eukaryotic genomes. The strategies employed take advantage of different DNA repair pathways to introduce mutations upon DNA cleavage. In bacteria however, the introduction of breaks by Cas nucleases in the chromosome has been described to kill the cell. Preliminary data indicates that this might not always be the case and that some DNA repair pathways could compete with CRISPR immunity allowing cells to survive. Using a combination of bioinformatics and genetics approaches we will investigate the interplay between CRISPR and DNA repair in bacteria with a particular focus on the widely used CRISPR-Cas9 system. The knowledge gained from this study will then help us develop novel tools for bacterial genome engineering. In particular we will introduce a NHEJ pathway in E.coli making it possible to perform CRISPR knockout screens. Finally using CRISPR libraries and multiplexed targeting, we will generate for the first time all combinations of pair-wise gene knockouts in an organism, a task that for now remains elusive, even for large consortiums and with the use of automation. This will enable to decipher genome-scale genetic interaction networks, an important step for our understanding of bacteria as a system.

Keywords: crispr,phage,genome editing,genetic interaction,gene regulation,dna repair
Law Enforcement agencies human factor methods and Toolkit for the Security and protection of CROWDs in mass gatherings (LETS-CROWD)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Fight crime, illegal trafficking and terrorism, including understanding and tackling terrorist ideas and beliefs
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Italy,Spain,Spain,Italy,Spain,Italy,Israel,Spain,Belgium,Romania,Belgium,United Kingdom,Portugal,United Kingdom,United Kingdom
Call: Human Factor for the Prevention, Investigation, and Mitigation of criminal and terrorist acts (H2020-SEC-2016-2017-1, 2016)
Start date: 2017-05-01
End date: 2019-10-31
Duration (months): 30.0
Total project cost (EUR): 2919307.5
EU funding (EUR): 2919307.5
Participants: 19
Project status: CLOSED

LETS–CROWD will overcome challenges preventing the effective implementation of the European Security Model (ESM) with regards to mass gatherings. This will be achieved by providing the following to security policy practitioners and in particular, LEAs: (1) A dynamic risk assessment methodology for the protection of crowds during mass gatherings centred on human factors in order to effectively produce policies and deploy adequate solutions. (2) A policy making toolkit for the long-term and strategic decision making of security policy makers, including a database of empirical data, statistics and an analytical tool for security policies modelling, and (3) A set of human centred tools for Law Enforcement Agencies (LEAs), including real time crowd behaviour forecasting, innovative communication procedures, semantic intelligence applied to social networks and the internet, and novel computer vision techniques. LETS-CROWD will be a security practitioner driven project, fostering the communication and cooperation among LEAs, first responders, civil protection and citizens in the fight against crime and terrorism during mass gatherings by a set of cooperation actions. The project will put citizens at the centre of the research and will assess and evaluate how security measures affect them, and how they perceive them, while respecting EU fundamental rights. LETS-CROWD impact will be measured under practical demonstrations involving seven LEAs and relevant emergency services units. In order to facilitate the assessment of the performance, transferability, scalability and large scale deployment of these solutions, the demonstrations will be conducted following eleven use cases.

Keywords: human factor,european security model,security,law enforcement agencies,emergency services,policy making toolkit,human centred technologies
Tools for Assessment and Planning of Aquaculture Sustainability (TAPAS)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: Research and Innovation actions
Countries involved: Spain,Spain,Ireland,Malta,Hungary,Hungary,Norway,Greece,France,Netherlands,Denmark,United Kingdom,United Kingdom,United Kingdom
Call: Consolidating the environmental sustainability of European aquaculture (H2020-SFS-2015-2, 2015)
Start date: 2016-03-01
End date: 2020-02-29
Duration (months): 48.0
Total project cost (EUR): 6918512.5
EU funding (EUR): 6918512.5
Participants: 17
Project status: CLOSED

Aquaculture is one of five sectors in the EU's Blue Growth Strategy, aimed at harnessing untapped potential for food production and jobs whilst focusing on environmental sustainability. TAPAS addresses this challenge by supporting member states to establish a coherent and efficient regulatory framework aimed at sustainable growth. TAPAS will use a requirements analysis to evaluate existing regulatory and licensing frameworks across the EU, taking account of the range of production environments and specificities and emerging approaches such as offshore technologies, integrated multi-trophic aquaculture, and integration with other sectors. We will propose new, flexible approaches to open methods of coordination, working to unified, common standards. TAPAS will also evaluate existing tools for economic assessment of aquaculture sustainability affecting sectoral growth. TAPAS will critically evaluate the capabilities and verification level of existing ecosystem planning tools and will develop new approaches for evaluation of carrying capacities, environmental impact and future risk. TAPAS will improve existing and develop new models for far- and near-field environmental assessment providing better monitoring, observation, forecasting and early warning technologies. The innovative methodologies and components emerging from TAPAS will be integrated in an Aquaculture Sustainability Toolbox complemented by a decision support system to support the development and implementation of coastal and marine spatial planning enabling less costly, more transparent and more efficient licensing. TAPAS partners will collaborate with key industry regulators and certifiers through case studies to ensure the acceptability and utility of project approach and outcomes. Training, dissemination and outreach activities will specifically target improvement of the image of European aquaculture and uptake of outputs by regulators, while promoting an integrated sustainable strategy for development.

Keywords: aquaculture,sustainable growth,coastal planning,environmental impacts