Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Diabetes Immunoengineering: Redesigning Encapsulated Cell Transplant Therapies (DIRECT Therapies)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United States,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-07-01
End date: 2021-06-30
Duration (months): 36.0
Total project cost (EUR): 269857.8
EU funding (EUR): 269857.8
Participants: 3
Project status: CLOSED

Diabetes Immunoengineering: Redesigning Encapsulated Cell Transplant Therapies Diabetes remains a global healthcare challenge, affecting 370 million people worldwide. Islet transplantation offers the potential to restore insulin function in diabetes-1 patients, and is proving successful in human clinical trials. However a major limitation is the requirement for patients to take global immunosuppressive drugs, often daily, for the remainder of their lives. These drugs can impact the quality of life for the patient, and may lead to an impaired immune system at risk of opportunistic pathogens. The scientific aim of this project is to develop innovative multifunctional materials for diabetes-1 cell therapies; those that can better support islet function and also direct the host immune system, removing the need for global immune suppression and enhancing transplant lifetimes. This project connects a talented young researcher with a background in chemistry, biomaterials science and immunoengineering, to a host institution with expertise in drug delivery and tissue engineering (Nottingham), and an internationally renowned outgoing institution (Boston Children's Hospital, Harvard Medical School) with expertise in transplant encapsulation and diabetes therapies. Combining the localised drug delivery expertise of the host institution, the diabetes-1 cell therapy transplant knowledge of the outgoing institution, and the researcher’s own expertise in immunoengineering presents a unique opportunity and new approach to addressing this healthcare challenge, and facilitates development of the researcher's career through a specified training-in-research program. Bridging the gap between the transplant immunology, biomaterials and drug delivery fields in this way meets the “Open Innovation, Open Science, Open to the World” EU vision towards Open Science and follows the road map for integrative research proposed by the UK Medical Research Councils for regenerative medicine research.

Keywords: stem cell transplants,induced tolerance,nucleic acid and drug delivery
Gender Quotas and the Democratic Quality of Local Decision-Making Processes in Clientelistic Regimes (GenderQuotas)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-09-01
End date: 2020-07-31
Duration (months): 21.0
Total project cost (EUR): 152125.05
EU funding (EUR): 152125.05
Participants: 1
Project status: CLOSED

Gender quotas are a widespread electoral reform aiming to tackle gender inequality in politics. A rich body of literature focuses on the impact of gender quotas on the articulation of women’s interests in national legislatures. Yet we know very little about the transformatory potential of gender quotas for local decision making. Do gender quotas challenge existing practices of local decision making and advance democratization in clientelistic regimes? This research project investigates the impact of gender quotas on the democratic quality of local decision-making processes in Albania. Do women push for transparency, accountability, and responsiveness? How does women’s engagement in local decision-making processes change over time? The project offers a unique and innovative perspective into the topic of gender quotas and democratization through the combination of theoretical and methodological approaches, original data, interdisciplinary approach, and comprehensive public engagement and dissemination of research findings. The proposal relates with a novel interdisciplinary approach that draws on studies of democratization, representation, political anthropology, and feminist institutionalism. The project will enhance the knowledge and skills of the Experienced Researcher by providing state-of-the-art training in data analysis and management – Python Programming Language and ATLAS.ti – advanced knowledge of theoretical and methodological approaches, and scientific and transferable skills. The knowledge and skills combined with networking and collaboration will place the Experienced Researcher in a competitive position among successful researchers in Europe.

Keywords: gender quotas,institutional change,democratization,decision making processes
Ready-to-use Multilingual Linked Language Data for Knowledge Services across Sectors (Pret-a-LLOD)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Spain,Spain,Ireland,Germany,Austria,Ireland,United Kingdom
Call: A multilingual Next Generation Internet (H2020-ICT-2018-2, 2018)
Start date: 2019-01-01
End date: 2022-06-30
Duration (months): 42.0
Total project cost (EUR): 2997181.25
EU funding (EUR): 2997181.25
Participants: 10
Project status: CLOSED

Language technologies increasingly rely on large amounts of data and better access and usage of language resources will enable to provide multilingual solutions that would support the emerging Digital Single Market in Europe. However, data is rarely ‘ready-to-use’ and language technology specialists spend over 80% of their time on cleaning, organizing and collecting datasets. Reducing this effort promises huge cost savings for all sectors where language technologies are required. An essential part of the Extract-Transform-Load process involves linking datasets to existing schemas, yet few specialists take advantage of linked data technologies to perform this task. In this project we aim to increase the uptake of language technologies by exploiting the combination of linked data and language technologies, that is Linguistic Linked Open Data (LLOD), to create ready-to-use multilingual data. Prêt-à-LLOD aims to achieve this by creating a new methodology for building data value chains applicable to a wide-range of sectors and applications and based around language resources and language technologies that can be integrated by means of semantic technologies, in particular the usage of Linguistic Linked Open Data (LLOD). The project will develop novel tools for the transformation and linking of datasets, and apply these to both data and metadata in order to provide multi-portal access to heterogeneous data repositories. We will study how we can automatically analyze licenses in order to deduce how data may be lawfully used and sold by language resource providers. Finally, we will provide tools to combine language services and resources into complex pipelines by use of semantic technologies. This will lead to sustainable data offers and services that can be deployed to many platforms, including as-yet-unknown platforms, and can be self-described with linked data semantics. This toolkit will be validated in four pilots, where novel data value chains will be built for pharma

Keywords: linguistic linked data,language resource sustainability,web services for natural language processing,semantic web technologies,multilingualism
Understanding ancient urbanism: site planning and unintended consequences of the Classic Maya city as a model (MAYURB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Mexico
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-01-01
End date: 2022-12-31
Duration (months): 36.0
Total project cost (EUR): 231524.16
EU funding (EUR): 231524.16
Participants: 2
Project status: CLOSED

The main goal of MAYURB is to study ancient urbanism using the Classic Maya Period (250-900 CE) as a model to understand city inception and expansion through time, while considering the diverse actors involved in its planning, use and transformation. The urban fabric of Palenque, Mexico, will be assessed with an interdisciplinary approach that delves into the decision-making process that underlies site planning and considers the limitation imposed by location; in addition, the project ponders the influence of traditions and believes in site selection and religious buildings’ astronomical orientation. While considering the negotiation processes and power relations involved in city inception and growth, MAYURB will explore the unintended consequences of city expansion, such as urban sprawl and sanitation. The project will develop around three main axes: the construction of a GIS platform to join archaeological, architectural and morphological data and to outline the physical reality in which the ancient Maya lived. The spatial analyses performed with GIS will lead the second line of investigation: archaeological excavations at Palenque in areas where it is more likely to uncover infrastructural works and their relative chronology. The third inquiry will explore the extent of authority in site planning and the agency of other urban actors with an interdisciplinary theoretical focus that spans from urban to anthropological theory. The methodological approach and theoretical contribution developed with MAYURB aim at providing a thorough understanding of the planning process and city performance in antiquity, beyond the time period and the geographical location in question. Three unique interchange appointments between UNAM-Mexico, UNIROMA1-Italy and ZRC SAZU-Slovenia at top-level Institutions are planned to fulfill MAYURB’s objectives, while increasing the Experienced Researcher’ skills.

Keywords: ancient urbanism,architecture,classic maya,infrastructure,site planning,archaeoastronomy
Quantum optomechanics at ROOm Temperature (Q-ROOT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: France,France,United Kingdom
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-09-01
End date: 2024-12-31
Duration (months): 76.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1143563.59
Participants: 3
Project status: SIGNED

5 years ago, the field of optomechanics has entered the quantum regime. By doing so, this domain which investigates the reciprocal interactions between light and mechanical motion has overcome the long-standing paradox of Quantum Mechanical effects at the macroscopic scale. Such outstanding achievement relies on the so-called “cavity nano-optomechanical” technology, which combines strongly reduced dimensions with ultra-high optical confinement, enabling very large optomechanical coupling rates at the nanoscale. In a more fundamental perspective, decreasing the size of optomechanical systems has enabled minimizing the detrimental effects of decoherence, resulting in a quasi-instantaneous collapse of quantum coherence at a macroscopic scale. At present, optomechanical systems seem to have reached their limits at cryogenic temperatures and remain overly sensitive to decoherence at room temperature to display any quantum behaviour. The project Q-ROOT proposes a novel cavity optomechanical approach showing such unprecedentedly large coupling rates that it will operate in the quantum regime at room temperature for the first time. Our concept relies on tethering a low-loss nano-optical scatterer at the edge of the lightest possible mechanical device that is a carbon nanotube resonator. This system is expected to outperform the state-of-the-art (including atom–based systems) by orders of magnitude, even at room temperature. Amongst objectives, Q-ROOT notably plans to demonstrate ground-state cooling, strong ponderomotive squeezing, the standard quantum limit, quantum non-demolition of mechanical Fock states, and optomechanical photon blockade at room temperature. Besides very fundamental impact, the unique sensing abilities of the system developed in Q-ROOT will be further utilized in order to perform quantum limited sensing applications at room temperature, paving a generalized use of optomechanics for quantum sensing and information technology at room temperature.

Keywords: quantum optomechanics,quantum mechanics
Exploring Gravity with Ultracold Cadmium and Strontium Optical Clocks and Bragg Interferometers (TICTOCGRAV)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Italy
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-06-01
End date: 2024-05-31
Duration (months): 72.0
Total project cost (EUR): 1999011.25
EU funding (EUR): 1999011.25
Participants: 1
Project status: SIGNED

The main aim of the TICTOCGRAV is to explore the limits of contemporary physics with a new generation of atomic quantum sensors, namely optical atomic clocks and atomic gravimeters. After 100 years of General Relativity and Quantum Mechanics, both theories have been tested at an unprecedented level. Direct detection of gravitational waves is a great success and represents another impressive confirmation of the present theory of gravitation GR. Indeed, we are living a “Quantum Revolution”, in which advanced quantum concepts are at the heart of several devices, from precision navigation and location on Earth to secure communication protocols based on entangled photons. Despite all these great success in both areas, unfortunately, we still lack a full comprehension at the fundamental level. As a matter of fact, a full quantum treatment of space-time is still under discussion in the community. While several theoretical attempts have been pursued, a clear solution to the problem does not exist yet. Very likely, an answer to this problem will come from high precision experiments capable of measuring tiny gravitational effects on quantum systems as atomic clocks and quantum inertial sensors. TICTOCGRAV will address this questions experimentally by performing ultimate precision tests of gravity with fountains of alkali-earth metals, namely Cadmium and Strontium atoms. Specifically, TICTOCGRAV will perform the highest precision tests so far of: -the weak equivalence principle (WEP) below 10^-13 with quantum probes, exploring also possible tests of spin-gravity couplings at the same level; - quantum interference of high precision clocks in a gravitational potential; demonstrating for the first time gravity induced decoherence mechanisms, opening the way towards a possible explanation of quantum to classical transition in macroscopically entangled quantum systems.

Keywords: optical lattice clocks,atom interferometers,cadmium,strontium
ERA-NET ON NANOMEDICINE (EuroNanoMed III)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: ERA-NET Cofund
Partnership: EuroNanoMed III (ERA-NET)
Countries involved: Estonia,Germany,Germany,Spain,Ireland,Italy,Israel,Taiwan, Province of China,Norway,Bulgaria,Greece,Lithuania,Poland,Romania,Türkiye,Belgium,Slovakia,Latvia,France,Czechia,Netherlands,Canada,Portugal
Call: ERA-NET on Nanomedicine (H2020-NMBP-ERA-NET-2016, 2016)
Start date: 2016-11-01
End date: 2022-10-31
Duration (months): 72.0
Total project cost (EUR): 15270000.0
EU funding (EUR): 5039100.0
Participants: 31
Project status: SIGNED

Nanomedicine is the application of nanotechnology to medicine and healthcare. The field takes advantage of the physical, chemical and biological properties of materials at the nanometer scale to be used for a better understanding of the biological mechanisms of diseases at the molecular level, leading to new targets for earlier and more precise diagnostics and therapeutics. Nanomedicine, rated among the six most promising Key Enabling Technologies, is one of the most important emerging areas of health research expected to contribute to one of the strategic challenges that Europe has to face in the future: Provide effective and affordable health care and assure the wellbeing of an increasingly aged population. EuroNanoMed III (ENM III) builds on the foundations of ENM I & II, which launched 7 successful joint calls for proposals since 2009, funded 51 transnational research projects involving 269 partners from 25 countries/regions, and allocated € 45,5 million to research projects from ENM funding agencies. ENM III consortium, reinforced with 12 new partners from Europe, Canada and Taiwan, is committed to fostering the competiveness of European nanomedicine actors taking into account recent changes in the landscape and new stakeholders and challenges, as identified in the SRIA in nanomedicine. The first joint call for proposals will be co-funded by ENM III partners and the EC. After the co-funded call, three additional joint transnational calls will be organized and strategic activities will be accomplished in collaboration with key initiatives in the field. ENM III actions focus on translatability of project results to clinical and industry needs.

Keywords: nanomedicine,transnational research project,diagnostics,regenerative medicine,research,predective personalized medicine,technologies,nanotechnology,health care,european nanomedicine actors
GroundForce: Grounding Natural Language Semantics in Video Games (GroundForce)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-10-01
End date: 2018-03-31
Duration (months): 18.0
Total project cost (EUR): 149867.0
EU funding (EUR): 149867.0
Participants: 1
Project status: CLOSED

While language is a natural way to interact with artificial characters or agents in video games, communication with agents currently tends to be limited to menu systems. To achieve smooth linguistic communication, utterances need to be grounded in the situation in which they occur. That is, the meanings of utterances must be learned from observing their use in some naturally occurring perceptual context. Recent years have seen much progress in the development of visually- or auditorily-grounded language understanding using novel machine learning techniques such as deep learning. At the same time, companies like Google DeepMind have introduced deep learning models that can learn to play games at super-human levels. We propose to take this research to the next step, by grounding natural language in video games. Grounding natural language in video games yields two main benefits. The first benefit is commercial in nature: with the global market for video games expected to reach $100 billion by 2017, there is clearly a large demand for more sophisticated interaction with in-game agents. Secondly, video games are a natural way to explore artificial intelligence techniques in a "simulated" world that is easier to understand computationally than the extremely complicated "real" world. The current project will explore natural language grounding in a small number of appropriate games. Once we are capable of grounding natural language in these games, we can translate utterances into straightforward actions for artificial agents. An example might be telling your team members to follow you, to take the left flank, or to duck when they are being shot at. Given the recent developments in machine learning and grounded language understanding, we believe that now is the perfect moment to explore these possibilities further.

Keywords: video games,natural language processing,machine learning,deep learning,neural networks
EKUPD (Gybrid)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Germany
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-09-01
End date: 2016-11-30
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Existing large off-road power train applications are dominated by diesel power train solutions. These applications are large fuel consumers and massive CO2, NOX and particulate emitters. Natural Gas reduces CO2 emissions by 20%, NOx by 90% and particulate emissions are removed. Moreover, Natural Gas prices are consistently at a fraction of diesel (25% in 2015). EKU’s proprietary control methods solve the technical barriers that natural gas engines have (e.g., sluggish performance restricted operation ranges), to replace diesel engines. GYBRID is an intelligent, natural gas-electric hybrid solution to facilitate electrification in off-road industrial applications (e.g., tug-boat, trucks, pressure pumps…). It uses natural gas or biomethane as its primary fuel and is supplemented for higher efficient power performance with a smart high energy dense battery array and sophisticated control technology. EKU GmbH develops hybrid industrial power at the leading edge of clean energy, electric motor technology, industrial battery assembly. EKU’s personnel has a strong track of record in the development and commercialization of new radically new horsepower concepts. GYBRID addresses the most important key buying criteria; reduction of operating costs (50%), reduction of downtime (by 80%) and reduction of emissions. For example, for hydraulic pumping trucks, customers save fuel costs of around €1.2M per unit annually, reducing their production expenditures up to 50 % and additionally increasing four times the lifetime of their power drive equipment. The customers can expect a payback within two years EKU, amongst others, was awarded first place in the 2014 Munich Cleantech Innovation Award which recognizes and rewards the best European clean technology venture. The jury rewarded EKU’s innovation that directly reduces the costs and emissions of energy transition from diesel to to natural gas/electric motor power providing superior performance gains in efficiency and productivity.

Keywords: electric engines,natural gas engines,hybrid power train,maritime transport,off road transport