Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
FAIR FOOD AND TRADE SYSTEMS FOR AFRICA THROUGH FOOD CONVERGENCE INNOVATION (FCI4AFRICA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Nigeria,South Africa,Germany,Netherlands,Greece,Canada,Kenya
Call: EU-African Union – towards climate-neutral, social just fair trade food systems (HORIZON-CL6-2024-FARM2FORK-01, 2024)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 4499353.24
EU funding (EUR): 4499353.24
Participants: 14
Project status: SIGNED

The FCI4Africa project champions a holistic approach to African agriculture, promoting fair, sustainable, climate-neutral, and health-promoting trading practices while ensuring economic prosperity at all levels and respecting human rights. It bridges the gap between technical compliance and social justice by empowering smallholder farmers and small and medium-sized enterprises, facilitating trade compliance through a digital platform, and enhancing food safety. By evaluating the impact of certification criteria like deforestation-free, organic, and fair trade, and guiding policymakers, FCI4Africa fosters a just transition for African farmers, processors, and traders, expanding their intra-African, and EU trading opportunities. Leveraging past projects and cutting-edge technologies, FCI4Africa connects stakeholders across diverse regions and jurisdictions, paving the way for a more sustainable and equitable African agricultural sector.

Keywords: food trade,africa,fairness,justness,sustainability,food convergence innovation,use cases
Navigating European Forests and forest bioeconomy sustainably to EU climate neutrality (ForestNavigator)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Climate
Destination: Climate sciences and responses for the transformation towards climate neutrality
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Italy,Ireland,Belgium,Portugal,Greece,Sweden,Czechia,Finland,Netherlands,France,Switzerland,China
Call: The contribution of forest management to climate action: pathways, trade-offs and co-benefits (HORIZON-CL5-2021-D1-01, 2021)
Start date: 2022-10-01
End date: 2026-09-30
Duration (months): 48.0
Total project cost (EUR): 5995240.8
EU funding (EUR): 5995237.3
Participants: 25
Project status: SIGNED

ForestNavigator aims at assessing the climate mitigation potential of European forests and forest-based sectors through modelling of policy pathways, consistent with the best standards of LULUCF reporting, and informing the public authorities on the most suitable approach to forest policy and bioeconomy. With a primarily European scope, ForestNavigator zooms into carefully selected EU Member States to enhance the consistency of the EU and national pathways, but the project also zooms out towards the global scale, and selected key EU trading partners, accounting for extra-EU future drivers and potential leakage effects. The project will rely on a newly developed integrated policy modelling framework for the EU forests and forest bioeconomy covering i) all relevant mitigation strategies from forest management to energy and material substitution, ii) climate change impacts, adaptation, and natural disturbances, iii) biophysical climate feedbacks, iv) systematically accounting for impacts on biodiversity, forest ecosystem services, and other forest functions, incl. jobs and green growth. To increase the accessibility of the models and pathways assessments, their understanding and transparency, a novel decision-making platform will be established consisting of the web-based ForestNavigator Portal, and a community of policy-makers, national authorities, and modelers, the Forest Policy Modelling Forum. To reach its ambitious objectives, ForestNavigator will i) harmonize, integrate and continuously update existing datasets by, including national inventories with new remote sensing data and models ii) start from complex forest and climate models and through emulators build them into operational policy modelling tools, iii) integrate biophysical and socio-economic information, iv) consider EU forests and forest bioeconomy in the broader context of other land use and economic sectors, v) rely on input from policy makers and other stakeholders.

Keywords: forest management,climate change impacts,mitigation,adaptation,integrated assessment,remote sensing,earth system modeling,carbon,biodiversity,economic modeling,bioeconomy,land use modeling
Contribution of adipose tissue and liver to cachexia associated with chronic kidney disease (StopKidneyCachexia)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-11-03
End date: 2027-11-02
Duration (months): 24.0
Total project cost (EUR): 242260.56
EU funding (EUR): 242260.56
Participants: 1
Project status: SIGNED

Cachexia is a life-threatening wasting syndrome, defined by an involuntary loss of body weight, that affects a large proportion of patients with advanced chronic diseases. Kidney diseases affect > 850 million people worldwide and represent the 10th leading cause of death. In this context, cachexia associated with chronic kidney diseases (KCx) is a huge burden in end-stage patients with kidney replacement therapies. Patients with KCx experience frailty, which worsens their quality of life (impacting their social- and professional life), hospitalization and mortality rates. So far, most research efforts have tried to identify primary pro-cachectic factors contributing to muscle wasting, but this was unfruitful in terms of therapeutics. Here, we are proposing a translational and interdisciplinary project that will focus on novel tissues (i.e adipose tissue and liver) with great relevance in the control of systemic energy metabolism. Preliminary data obtained in collaboration with the host laboratory have shown that these two tissues undergo a strong remodeling of their glucose and lipid metabolism, which could contribute to energy loss and body wasting. The main objectives of the project will be: 1) to understand the mechanisms by which altered metabolic pathways contribute to wasting in fat, liver and muscle cells; 2) to assess the biomarker potential of products of these metabolic pathways for early diagnosis of patients with KCx; and 3) to assess the therapeutic potential of targeting these metabolic pathways in mouse models of KCx. With this project, we will develop a novel research axis combining my expertise in the field of cachexia and metabolism to the expertise of the host in the field of kidney diseases. The project will be supported by highly relevant in vitro and in vivo models, access to patients’ samples, and innovative techniques. This fellowship will allow to develop my independency and to get a competitive research profile to pursue an academic career.

Keywords: chronic kidney diseases cachexia adipose tissue liver glucose and lipid metabolism
Quantitative reconstruction of past seawater oxygen concentrations (OxyQuant)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,Switzerland
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-03-01
End date: 2026-12-31
Duration (months): 46.0
Total project cost (EUR): 321472.8
EU funding (EUR): 321472.8
Participants: 2
Project status: SIGNED

Because of their sheer size and tight coupling to the atmosphere the oceans are a pivotal climate regulator. Their interaction with climate is associated with both physical processes such as ocean circulation, which redistribute heat, freshwater, and carbon around the globe, and biogeochemical processes, which ultimately control the strength of the biological carbon pump, and by inference the storage of remineralized carbon in the ocean interior. Seawater oxygen concentrations are intimately linked to both type of processes and are thus a crucial parameter for assessing the state of the oceans today but also in the past. Despite the crucial role these processes play on climate and climate variability, they remain surprisingly poorly understood. While paleoceanography offers a unique opportunity to observe the state and behaviour of the oceans under different boundary conditions, no reliable and widely applicable method for the quantitative reconstruction of past bottom water oxygen concentrations (BWO) has yet been established. Thus, the objective of OxyQuant is to develop and calibrate an innovative proxy toolkit to reliably reconstruct past BWO. To this end, three fundamentally independent approaches for which promising preliminary observations exist will be calibrated using a range of sediments retrieved from contrasted marine environments. While the first approach associated with the sedimentary concentrations of redox-sensitive trace metals, has already attracted much interest over the past decades, the other two methods, namely the organic matter – associated iodine and the stable isotope composition of authigenic cerium (δ142Ce) archived in fossilised fish debris, are novel and have yet to be comprehensively tested. Combined with their application in two case studies on glacial – interglacial time scales, OxyQuant will provide the paleoceanographic community with the means to finally fill the gap of quantitative reconstructions of past BWO.

Keywords: paleoceanography,oxygenation,redox sensitive metals,rare earth elements,element cycles,marine sediments
IMPLANTABLE ECOSYSTEMS OF GENETICALLY MODIFIED BACTERIA FOR THE PERSONALIZED TREATMENT OF PATIENTS WITH CHRONIC DISEASES (ISOSHopOn)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Research and Innovation actions
Countries involved: Spain,Greece
Call: Hop on Facility (HORIZON-WIDERA-2023-ACCESS-06, 2023)
Duration (months): 36.0
Total project cost (EUR): 598750.0
EU funding (EUR): 598750.0
Participants: 2
Project status: SIGNED

The EIC Pathfinder project “ISOS” is developing the first biomedical product for the in-situ fabrication and auto-renewed delivery of therapeutic compounds employing large ecosystems of probiotic genetically engineered bacteria (GEB) integrated in a biomaterial-based bioreactor. The encapsulated GEB populations produce the therapeutic molecules "on demand", stimulated by the signals of the pathological environment within the patient. To accomplish this, different bacteria populations should coexist inside the biomaterial scaffold and maintain a dynamic equilibrium of the GEB species to guarantee the survival of the drug producing-bacteria. The election of microbial strains with the greatest adaptability to the scaffold and the particular pathological environment is key to achieve the greatest efficiency of production and exportation of therapeutic molecules. In silico simulations (UCM partner) offer the possibility to create digital representations to model interactions between bacteria and specific biomolecules, between bacteria and tissues/organs of interest, as well as cell-cell interactions. This mathematical modeling of their dynamics will require complete biological validation of these interactions and decipher how different strains of bacteria might coexist in simple and complex silk fibroin-based ecosystems, as well as to analyze the adaptability of each bacterial species to the specific external microenvironment. The addition of the new Widening partner ResQ Biotech through the ISOSHopOn project will allow the realization of these additional validation tasks and will be critical to understand the underlying mechanisms of microbiome–host–environment interactions. Such functional/mechanistic understanding is necessary for protecting, rationally modulating, or even exploiting the interaction of scaffold-microbiomes to target different diseases.

Keywords: implantable bioreactor,bacteria,protein,peptide,cell cell interaction,cell host interaction
THERANOSTICS ECOSYSTEM FOR PERSONALISED CARE (Thera4Care)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Innovative Health Initiative
Action type: Research and Innovation actions
Partnership: IHI (JU-JTI)
Countries involved: Hungary,Italy,Belgium,Denmark,Finland,Sweden,France,Israel,Netherlands,United States,Switzerland,United Kingdom,Germany,Spain,Austria
Call: Development and proof of principle of new clinical applications of theranostics solutions (HORIZON-JU-IHI-2023-05, 2023)
Start date: 2024-10-01
End date: 2029-09-30
Duration (months): 60.0
Total project cost (EUR): 25329093.0
EU funding (EUR): 14130974.75
Participants: 30
Project status: SIGNED

Thera4Care represents a large unique consortium, gathering well-established European academic radiotheranostic centres, strong industry partners, European and medical societies focusing on training and education, a patient advocacy group spearheaded by an experienced project management group. Thera4Care aims to establish a European network of radiotheranostics centres able to rapidly develop and implement radiotheranostics tools and solutions to drive precision health. The overarching vision of Thera4Care is to revolutionise radiotheranostics procedures by establishing, implementing, and disseminating standardised scalable methods to produce and efficiently administer key radiotheranostics solutions. Thera4Care focus is on developing diagnostic and therapeutic ligands tailored to key disease areas (such as solid tumours), aligning with the growing significance of multi-modal radiotheranostics solutions dominated by radionuclide-based therapy and companion diagnostics. Thera4Care project is scheduled for 5 years and consists of 9 work packages. WP1 handles Project Management, WP2 focuses on Regulatory aspects, WP3 plans Preclinical studies, WP4 provides Supply chain, WP5 develops Clinical Trials, WP6 generates AI models, WP7 focuses on Dosimetry, WP8 develops Precision Imaging components, while WP9 focuses on Education and Dissemination. Thera4Care will advocate for the progress of radiotheranostics, with the goal of increasing medical knowledge and enhancing treatment efficacy for improved patient outcomes. Concurrently, aims to coordinate scientific initiatives across European landscapes, leveraging a comprehensive and multimodal approach to cancer therapy applicable to various cancer types. Lastly, will work on the establishment of sustainable supply and production networks and the upscaling of production methodologies and supply chains across the public and private sectors, to enhance the availability of radionuclides.
A next-generation automated, connected, and standardised process for increased safety, efficiency, and sustainability of Li-ion BATTEry REVERSE logistics (BatteReverse)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Cross-sectoral solutions for the climate transition
Action type: Research and Innovation actions
Partnership: Batteries (co-programmed)
Countries involved: France,Spain,Czechia,Greece,Poland,Germany
Call: Streamlined collection and reversed logistics, fully automated, safe and cost-efficient sorting, dismantling and second use before recycling (Batteries Partnership) (HORIZON-CL5-2022-D2-01, 2022)
Start date: 2023-05-01
End date: 2026-10-31
Duration (months): 42.0
Total project cost (EUR): 4910972.0
EU funding (EUR): 4910972.0
Participants: 14
Project status: SIGNED

BatteReverse aims to enable the next generation of battery reverse logistics (RL). It will develop a more efficient and universal method for battery discharge and first diagnosis for a wide range of Li-ion battery types, safety packaging with a monitoring system reducing thermal runaway risk during transportation of batteries, automated dismantling and sorting of battery components based on a safe and more efficient human-robot collaboration, and a more precise and faster Remaining Useful Life assessment of battery modules for 2nd life applications based on acoustic testing and machine learning algorithms. On top of that, BatteReverse will develop a Battery Data Space with standardised labelling and battery passport functionalities to improve battery identification. We will connect the stakeholders through a community platform and analyse the entire RL process by a digital twin (DT) simulation that will optimise profitability of RL circular business models. The innovations will be integrated and demonstrated in an operational environment in two use-cases for end-of-first-life (EoFL) EV batteries - recycling and repurposing – mirrored with the DT simulation. By 2026 we expect these developments to contribute to following outcomes: increase recycling efficiency by 5%, raise share of repurposed EoFL batteries to 10%, reduce risk of severe events in reverse logistics to 1/10.000, successfully simulate two successful RL business models and to have a stakeholder’s community platform with 50+ stakeholders. These outcomes will contribute to the sovereignty of the EU in the battery sector. By further uptake of the developed results beyond the project, BatteReverse targets to avoid the use of 3.691 tonnes/year of primary critical raw materials, on top of that avoid the deployment of 100,8 MWh capacity of new batteries yearly while capturing an extra €30,24 million/year value out of EoFL batteries and avoiding 31 severe risk events/year within the EU RL battery chain by 2029.

Keywords: reverse logistics,ev batteries,repurposing,recycling,battery passport,automatisation,digital twin,rul assessment
InnoVatIve processing Technologies for bio-based foAmed thermopLastics (VITAL)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Made in Europe (co-programmed)
Countries involved: Finland,Germany,United Kingdom,Portugal,Spain,Türkiye,Italy
Call: Manufacturing technologies for bio-based materials (Made in Europe Partnership) (RIA) (HORIZON-CL4-2021-TWIN-TRANSITION-01, 2021)
Start date: 2022-06-01
End date: 2025-11-30
Duration (months): 42.0
Total project cost (EUR): 5623018.75
EU funding (EUR): 5623016.0
Participants: 17
Project status: SIGNED

VITAL aims to generate fundamental knowledge and expertise that will underpin future European activities to substitute existing synthetic thermoplastics with those from bio-based sources and in so doing, enable the European the polymer processing sector to achieve a paradigm shift towards bio-based alternatives for cleaner, more climate neutral industrial value chains. This will be achieved through the development of thermoplastic foaming processes, combined with smart digital control approaches, that will enable bio-based thermoplastics to be processed both on traditional processing equipment (for foam injection moulding and bead foaming) as well as developing a globally unique 3D printing approach for foamed thermoplastics. These processing technologies represent three 'value-chains'. In addition, bio-based thermoplastic mechanical recycling developments will underpin progression of engineering applications towards a 'Circularity by Design' approach. The knowledge produced will be widely disseminated through various conduits, including a Learning Factory that aims to give access to pilot scale industrial lines for each of the 3 value chains in order to reduce the risk for industry for adoption of the technologies. VITAL brings together a world-leading consortium consisting of industrial processors and equipment manufacturers along with end-user partners from the automotive, electronics and marine sectors and leading research and technologies organisations from across Europe. The 6 use cases in VITAL combine to address the expected outcomes, and create pathways to mitigate ~75,000 tonnes CO2 eq/year from fossil-based materials through a conversion to bio-based materials. The consortium along with the Advisory board will provide a multiplier effect to broaden these impacts with further applications and uses. VITAL's disruptive approaches will help industrial adoption by addressing the cost-challenges of bio-based materials by optimising processing and material use.

Keywords: bio based materials,foamed polymers,foam injection moulding,3d foam printing,3d printing,bead foaming,autoclave foaming,
Industrial Cluster FLEXibility platform for sustainable FACTories to reduce CO2 emissions and to enable the Energy Transition (FLEX4FACT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Innovation actions
Partnership: Processes4Planet (co-programmed)
Countries involved: Norway,Spain,Italy,Germany,Ireland
Call: Design and optimisation of energy flexible industrial processes (Processes4Planet Partnership) (IA) (HORIZON-CL4-2021-TWIN-TRANSITION-01, 2021)
Start date: 2022-06-01
End date: 2025-11-30
Duration (months): 42.0
Total project cost (EUR): 21210643.75
EU funding (EUR): 17997020.0
Participants: 26
Project status: SIGNED

The Flex4fact project aims to develop an end-to-end ecosystem that takes a modular approach to enable flexible manufacturing in industry and create the conditions for the necessary energy transition in which all stakeholders can participate and benefit. Currently, complex process industries and the segment of mixed clusters and distributed renewable energy flows are not covered. Indeed, at least three key elements of the Flex4Fact approach differ from current offerings: 1) enabling industrial flexibility through digital process twinning and machine learning techniques to address complex operational scenarios and exploit the full potential of the selected industrial cases; 2) the end-to-end approach of the Flex4Fact platform, covering the entire technology stack required to achieve the results; 3) a modular and multi-level approach that leverages flexible, hybrid architectures, open protocols, and standard interfaces to enable greater flexibility in the system itself and associated service offerings, remove barriers to entry for vendors in the value chain, and ensure data communication with existing IT legacy systems. As a digital enabler for flexible energy consumption, the Flex4Fact platform will meet the needs of companies of all sizes, including SMEs that are affected by rising energy prices and have less "financial muscle" to deploy a combination of IT, manufacturing, and energy solutions (93% of European companies have fewer than 10 employees and only 1 in 5 SMEs are highly digitized). The Flex4fact platform will also reduce the digital divide between North and Southern Europe, another crucial aspect for European competitiveness: in fact, it will be developed by a balanced European consortium in which critical technologies will be developed and implemented by several partners in five industrial contexts, from North to South in Europe.

Keywords: industrial cluster platform