Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Minimal Surfaces in 3-manifolds (MSI3M)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Türkiye
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2008-10-01
End date: 2012-09-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Dr. Coskunuzer will undertake research in Differential Geometry and Geometric Topology. He will investigate the problems in minimal surface theory in hyperbolic space by using topological techniques. There are five main problems in the project. PROBLEM 1: (Universal Cover Conjecture) The first one is a famous classical 3-manifold topology problem, namely The Universal Cover Conjecture. The Conjecture asserts that the universal cover of any irreducible 3-manifold with infinite fundamental group is a 3-ball. This problem is one of the most famous problems in geometric topology. PROBLEM 2: (Intersections of Least Area Planes in Hyperbolic 3-space) The second main problem is about Least Area Planes in Hyperbolic 3-space. In recent years, Dr. Coskunuzer showed very strong generic uniqueness results on the subject. Now, he is studying the intersections of different least area planes with non-transverse asymptotic boundary. He is aiming to prove that these planes are also disjoint. Such a result will have a very wide range of applications in geometric topology. PROBLEM 3: (Properly Embedded Least Area Planes in Hyperbolic 3-space) Dr. Coskunuzer is aiming to prove another ambitious conjecture about the least area planes in hyperbolic 3-space in this project. The conjecture is that any least area plane in hyperbolic 3-space whose asymptotic boundary is a simple closed curve is properly embedded. He already got very strong partial results about the conjecture. PROBLEM 4: (Hyperbolic 3-manifolds with Minimal Foliation) The next problem in the project is the existence of a hyperbolic 3-manifold with foliation by minimal surfaces. This is also a famous question in geometric topology. PROBLEM 5: (Embedded Plateau Problem) The aim is to prove the following conjecture: For any nullhomotopic curve C in a 3-manifold M, there is an embedded disk which minimizes the area among the embedded disks in M with boundary C.

Keywords: minimal surfaces,least area plane,3-manifolds,hyperbolic geometry,universal cover conjecture,foliations,plateau problem
The research, training and mobility programme in Trentino (TRENTINO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2007-2-3-COFUND, 2007)
Start date: 2009-06-25
End date: 2014-06-24
Duration (months): 60.0
Total project cost (EUR): 6650000.0
EU funding (EUR): 2660000.0
Participants: 1
Project status: CLOSED

Trentino is the right bay for research and development. It hosts a large number of research labs from environmental studies to high-tech technologies. The Province of Trento allocates several resources such as infrastructure, real estate and funds to encourage research and innovation. Many institutes, both public and private, local, national and international have established their research units in Trento and Rovereto in order to transfer the knowledge from the research arena to industries. In order to facilitate the development of the research environment the PAT decided to start its Research Mobility programme. The Trentino programme started in 2003 with the first call for proposals for incoming research post-docs and implemented in 2006 with the call for proposals for Research Teams. The general objective of this proposal is to increase the number of trans-national fellowships awarded, to introduce a new outgoing and reintegration scheme and to improve the fellows’ condition. Thanks to the COFUND action the number of researchers coming from outside Italy could be increased and the local/Italian researchers be reintegrated. Besides, some researchers could profit of international experiences and then come back to Trentino. Furthermore the conditions of the fellows will be improved by promoting the implementation of the conditions described in “The European Charter for Researchers and The Code of Conduct for the Recruitment of Researchers”, in particular by offering employment contracts instead of stipends to the fellows, by establishing a career development plan at the beginning of the project and by introducing an assessment questionnaire at the end of the project. Another objective is to improve the Internet website and its English version.

Keywords: autonomous province,reform process,incoming,outgoing,excellence,reintegration,health sciences,humanities,natural sciences,physical sciences,technolgocal sciences
Visualizing Molecular Change (VISCHEM)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Physical and Analytical Chemical sciences
Countries involved: Sweden
Call:  (ERC-2008-AdG, 2008)
Start date: 2008-12-01
End date: 2013-11-30
Duration (months): 60.0
Total project cost (EUR): 2056000.0
EU funding (EUR): 2056000.0
Participants: 1
Project status: CLOSED

What knowledge is needed to characterize function of a biomolecule, molecular material or a chemical reaction mechanism? Structure has long been considered to be the key information and several powerful techniques like X-ray crystallography and multidimensional NMR have been developed, following the notion that seeing is believing, to provide equilibrium (static) structures of molecules. At the same time function of a molecular system implies change of structure and in order to characterize and understand how a biomolecule or material works it is necessary to know how and why the structural changes occur. The How is related to finding out precisely which structural changes occur, which atoms are involved, how are they affected, which bonds are broken, how does energy and charge flow through the molecule, and what are the temporal characteristics of the changes. The Why is associated to energetics and interactions what is the energy landscape that connects reactants, intermediates and products and how do molecules interact with each other and with their environment? Structural and dynamical information is today generally obtained in separate experiments static structures from X-ray crystallography, cryo-electron microscopy and multidimensional NMR, while molecular time scale dynamics are obtained from e.g. ultrafast laser spectroscopy. Dynamics from such experiments does not provide direct information on structural changes, but has to be inferred from often sophisticated analysis of spectroscopic data. Thus, there is a great need for experiments that can provide direct information on structural changes occurring on the molecular time scale of picoseconds and femtoseconds. The goal of this project is to develop a table-top experimental setup for sub-ps X-ray spectroscopy to obtain molecular time scale geometrical and electronic structural information of chemical and biological processes for deeper insights into molecular reaction mechanisms.

Keywords: time resolved x-ray spectroscopy,ultrafast spectroscopy
Repurposing and enriching images for immersive storytelling through smart digital tools (FotoInMotion)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Estonia,Italy,Greece,Belgium,France,Netherlands,Netherlands,Luxembourg,Portugal
Call: Tools for smart digital content in the creative industries (H2020-ICT-2017-1, 2017)
Start date: 2018-01-01
End date: 2020-12-31
Duration (months): 36.0
Total project cost (EUR): 2548288.75
EU funding (EUR): 2548288.75
Participants: 10
Project status: CLOSED

The amount of digital content available to creative industries is growing exponentially, driven by the ubiquitous use of smartphones and the proliferation of social media: (1) there is a tremendous increase in the amount of photographic content (more than 1.8 billion photos are uploaded to social media platforms each day); (2) the ongoing transformation of factual, entertainment and social media publishers and platforms from textual and photo-centric format to video-driven format (more than 400 hours of video are being uploaded to YouTube each minute); (3) the increasing impact of 3D and virtual reality for providing immersive storytelling experiences, offering new ways of audience engagement and monetization for content creators in the upcoming years. Acknowledging the above, the following critical questions become imminent in both content production and dissemination contexts: how to repurpose this massive amount of content; what kind of innovative tools are most suitable for this process; and finally how these tools can offer new forms of monetization possibilities for creative industries' professionals. FotoInMotion, sets to solve these critical questions and provide an innovative solution to the repurposing of content by offering automated tools for innovative contextual data extraction, object recognition, creative transformation, editing and text animation as well as state of the art 3D conversion options that allow content creators to transform their photos into highly engaging spatial and three dimensional video experiences. FotoInMotion will focus on three major creative industries sectors: photojournalism to develop interactive photo driven stories; fashion, by opening up new forms of marketing, product placement and event coverage; and festivals, by enabling PR and publicity managers to communicate the festival experiences and engage audiences through immersive communication and repurposing festival archives.

Keywords: immersive storytelling software,3d conversion,metadata extraction,sensory information extraction,non linear editing tools,cloud based processing and rendering,photojournalism,fashion,festivals
Structural Biology of Human Ribosome Biogenesis (Human-Ribogenesis)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Germany
Call: ERC Advanced Grant (ERC-2019-ADG, 2019)
Start date: 2020-10-01
End date: 2025-09-30
Duration (months): 60.0
Total project cost (EUR): 2080137.5
EU funding (EUR): 2080137.5
Participants: 1
Project status: SIGNED

The emergence of numerous diseases caused by defective assembly of ribosomes calls for a deeper understanding of human ribosome biogenesis. Yet, in human cells the assembly of ribosomal subunits is a vital process of daunting complexity, which requires several hundreds of assembly factors (AFs). Together with small nucleolar RNAs (snoRNAs) these factors facilitate a cascade of modification, processing and folding events of the ribosomal RNA (rRNA) that are tightly coordinated with the incorporation of a large set of ribosomal proteins between the nucleolus and the cytoplasm. This process has been extensively studied in fungal model organisms such as S. cerevisiae, however, assembly and rRNA processing pathways differ significantly between yeast and mammals. Many unique AFs have been identified in humans and several diseases, so-called ribosomopathies, have been assigned to ribosome biogenesis defects. Yet, so far only a single publication (Ameismeier et al., 2018) provides direct molecular information on the structural basis and architectural transitions of human ribosome maturation. Therefore, I propose to provide a near complete structural inventory of human ribosome biogenesis by using state-of-the-art cryo-electron microscopy (cryo-EM) on purified native pre-ribosomal particles. Corresponding analysis by chemical cross-link mass spectrometry, Nanopore sequencing and cryo-tomography as well as functional assays probing for nuclear export and RNA processing defects will gain complementary functional information. Finally, shot-gun cryo-EM of total pre-40S, pre-60S and 90S intermediates will be established in order to quantitatively characterize the equilibrium flow of ribosome assembly in normal and challenged human cells. Together, these insights will provide the basis for a mechanistic understanding of human ribosome biogenesis and will thereby lay the foundation for better relating this process to regulatory pathways and disease.
Human Gonad Developmental Cell Atlas (HUGODECA)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Understanding health, wellbeing and disease
Action type: Research and Innovation actions
Countries involved: Germany,Sweden,France,France,Denmark,United Kingdom
Call: Pilot actions to build the foundations of a human cell atlas (H2020-SC1-2019-Single-Stage-RTD, 2019)
Start date: 2020-01-01
End date: 2022-06-30
Duration (months): 30.0
Total project cost (EUR): 4822198.75
EU funding (EUR): 4822197.0
Participants: 10
Project status: SIGNED

The single ground-breaking goal of the HUGODECA project is to describe the cellular composition and organization of the developing human gonads and to understand how it changes during sex determination into testes in males and ovaries in females. What are the underlying mechanisms and first molecular and cellular events that accompany the differentiation and divergence of embryonic gonads? How and when do male and female cell lineages diverge and specific traits emerge? HUGODECA focuses on healthy gonad development, but our reference model will be tested using specific ex vixo assays mimicking Differences/Disorders of Sex Development (DSD). To reach this ambitious goal, the HUGODECA consortium brings together leading European academic and industrial experts (from 5 different EU countries). It includes active contributors and executives of the Human Cell Atlas (HCA) which will ensure complementarity with other ongoing HCA efforts. The overall HUGODECA concept is grounded on the integration of multiple synergistic expertise and technologies: Single cell profiling, Spatial transcriptomics, 2D Mass cytometry and cyclic immunofluorescence and 3D imaging of optically cleared gonads. HUGODECA will implement novel tools, analytical and computational methods to process and integrate multidimensional OMICS and image data across different platforms. It will evaluate the accuracy of ex vivo culture models of human gonadal development and assess consequences of altering key signaling pathways. HUGODECA will build the first multiscale developmental cell atlas and unprecedented reference maps of male and female human gonads. It will implement an interactive and multi-dimensional online portal for clinicians, scientists and public including DSD patient associations. HUGODECA shall improve our understanding of DSD, which is a major pediatric concern, requiring complex and highly specialized medical treatment and psychosocial care.

Keywords: gonad,embryo,sex determination,3d imaging,human cell atlas,microscopy,bio imaging,single cell genomics,development,spatial transcriptomics,infertility,differences of sex determination
Support to the implementation of the Long-term EU-AU Research and Innovation Partnership for Food and Nutrition Security and Sustainable Agriculture (LEAP4FNSSA)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Coordination and support actions
Countries involved: Egypt,Austria,Germany,Italy,Germany,Ethiopia,South Africa,Germany,Spain,Uganda,Germany,Finland,Finland,Hungary,Sweden,Greece,France,Czechia,Netherlands,Kenya,Denmark,United Kingdom,United Kingdom,Portugal,Burkina Faso,Senegal,Ghana,Nigeria
Call: Support to the implementation of the EU-Africa Research and Innovation Partnership on Food and Nutrition Security & Sustainable Agriculture (FNSSA) (H2020-SFS-2018-1, 2018)
Start date: 2018-11-01
End date: 2022-10-31
Duration (months): 48.0
Total project cost (EUR): 5136250.55
EU funding (EUR): 5135606.25
Participants: 39
Project status: CLOSED

The general objective of LEAP4FNSSA is to establish a sustainable structure, or ‘Platform’, for the efficient and coherent implementation of the AU-EU Research and Innovation Partnership as described in the FNSSA Roadmap. Under the aegis of the HLPD and its Bureau, and by building upon related projects such as RINEA, CAAST-Net. Plus, ProIntensAfrica and LEAP-Agri, LEAP4FNSSA aims to achieve this overall objective through three specific objectives: - Increase the synergies and coherence between actors, research and innovation projects, initiatives and programmes, through the development of institutional alliances and clusters of projects; - Develop a learning environment and a large knowledge base, including monitoring and evaluation activities, creating communication and links between different initiatives to improve STI cooperation; - Establish a long term and sustainable governance and funding mechanism for the Platform. To reach these objectives, LEAP4FNSSA will build on a large consortium of experienced partners and implement a methodology based on 3 principles: long-term impact, relevance of the outputs to the HLPD, and innovative actions. Long-term impact of the CSA relates to its main objective to enable and catalyse the transformation of the existing AU EU FNSSA Partnership into a bi-continental Platform for collaboration, organised along a Knowledge and Management Communication Framework. Outputs relevant to the HLPD will be achieved by connecting and framing activities of all Work Packages on top of the supporting activities specifically requested in the SFS-33-2018. Innovative actions are foreseen to run the Platform efficiently throught e.g. the development of a new approach to information mapping, text and data mining, and testing of multistakeholder alliances at a regional level and the mobilisation of actors to manage research and innovation programming in a 4-steps management cycle.

Keywords: eu au partnership,food and nutrition security,sustainable agriculture
A Reconfigurable robot workCell for fast set-up of automated assembly processes in SMEs (ReconCell)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Germany,Germany,Austria,Finland,Lithuania,Slovenia,Denmark
Call: ICT Innovation for Manufacturing SMEs (I4MS) (H2020-FoF-2015, 2015)
Start date: 2015-11-01
End date: 2019-02-28
Duration (months): 40.0
Total project cost (EUR): 6306457.0
EU funding (EUR): 5561569.0
Participants: 9
Project status: CLOSED

ReconCell develops a new type of robot workcell, its required process infrastructures and the economic framework for automated robot assembly, especially designed for the needs of SMEs. SMEs would benefit from robotic automation, but often cannot use it due to set-up & maintenance complexity. This requires expert knowledge and time for configuration and programming, which is too costly for them. Robotic automation is, thus, normally economically infeasible for SMEs, especially for small batch sizes. ReconCell develops an easy to (re-)configure and (re-)program workcell, making robot solutions commercially viable even for small batch sizes (~1000 units) by reducing set-up & maintenance effort substantially. Specifically, the ReconCell System is based on a layered concept where we start together with the customer with business modelling the planned product assembly based on the ReconCell System to assess its economic viability and provide decisive Key Performance Indicators (KPIs). On approval, the next layer of the ReconCell System implements assembly with automated testing in simulation. Here we use reconfigurable hardware elements to design the required workcell layout and assembly processes. After verification, product assembly takes place in the real workcell under machine vision-based monitoring and novel force-based control of execution to assure product quality using the KPIs. We demonstrate the capabilities of the layered ReconCell System on three real use cases provided by the SMEs of our consortium and two more use cases, established through an open call. In addition, the consortium has started to establish a network of potential ReconCell users to disseminate information about ReconCell technologies to all actors in the value chain, and to raise awareness about the possibilities of automated robot assembly in SMEs. The final aim is to establish a company that commercializes the workcell and associated technologies developed in the ReconCell project.

Keywords: autonomous robots,automated robot assembly,robot programming,reconfiguration,simulation,business modeling
e-DNA BotStop (e-DNA BotStop)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: United Kingdom
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-05-01
End date: 2019-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In the last decade there has been an explosion in Online Travel Agents (OTAs) worldwide. OTAs undertake the mammoth task of undercutting the flight prices of major airlines through the use of Bots (an internet Bot, also known as web robot, WWW robot or simply bot, is a software application that runs automated tasks (scripts) over the Internet.). Bots are used to scrape airlines for valuable data to benchmark aggregate flight costs, which drives down prices for the consumer. Whilst beneficial to consumers, scraping harms travel companies because: • Bots can engage with a websites’ server hardware and cause website traffic to run slower, in some cases causing server downtime and Direct Denial of Service (DDoS) • Long term Search Engine Optimization (SEO) damage; distorting analytical marketing metrics. • Diverting customers to purchase products via third party resellers, limiting chances for up-sell and cross sell opportunities. This problem is tackled by anti-scrape approaches. However, current anti-scrape/booking bot solutions are only capable of distinguishing between human traffic and bot traffic through supervised algorithms that do not work to the degree of efficacy required. Our proposed solution is BotStop an algorithmic approach to identifying Bots and scrapers and to policing malicious application traffic. eDNA will provide a solution which reintroduces transparency into the process of purchasing flights and will streamline customer website experience to ensure a more stress-free experience

Keywords: bots machine learning defence travel industry