Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Soil biodiversity enhancement in European agroecosystems to promote their stability and resilience by external inputs reduction and crop performance increase (SoildiverAgro)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Research and Innovation actions
Countries involved: Spain,Spain,Estonia,Estonia,Germany,Spain,Germany,Spain,Spain,Belgium,Finland,Finland,Belgium,Belgium,Finland,Belgium,Czechia,Denmark
Call: Biodiversity in action: across farmland and the value chain (H2020-SFS-2018-2, 2018)
Start date: 2019-06-01
End date: 2025-05-31
Duration (months): 72.0
Total project cost (EUR): 6999888.75
EU funding (EUR): 6999888.75
Participants: 22
Project status: SIGNED

With the long-term view of fostering synergies between crop production, biodiversity and the delivery of ecosystem services of local, regional and global relevance, the main objective of SoildiverAgro is the adoption of new management practices and cropping systems that enhance soil genetic and functional biodiversity to reduce the use of external inputs while increasing crop production and quality, the delivery of ecosystem services and the EU agricultural stability and resilience. To achieve this objective 90 farm systems will be analysed in 9 pedoclimatic regions in Europe and 15 field case studies will be designed and established in six of the pedoclimatic regions. The focus will be on the use of innovative management practices based on soil mycorrhiza and plant growth promoting bacteria (including the development and testing of new commercial products), appropriate management of soil organisms (e.g. fungivores), the application of suitable crop rotations, multiple cropping and intercropping, the development of pest alert systems, the use of nutrient catch crops, the use of trap crops for pest control, the use of by-products as soil ameliorants and the application of adequate tillage systems. SoildiverAgro outputs consider: 1) enhancement of soil biodiversity; 2) reduction of pest/diseases incidence; 3) increases in plant growth and development; 4) increases in crop yields, quality and value; 5) the reduction of inputs; 6) increases in soil fertility; 7) reductions of soil contamination; 8) reduction in GHG emissions; and 9) increases in soil C sequestration. To ensure rapid adoption of measures fostering soil biodiversity, improved methods and tools including for monitoring will be developed. The successful crop management practices will be also analysed from the environmental, economic and social perspectives. Operational diversity targets will be defined, with development of best agricultural practice strategies and tools for existing EU policies update.

Keywords: functional diversity,genetic diversity,microorganisms,macroorganisms,ecosystem services,methods,tools,farm resilience,farm stability,crop health,crop production,inputs reduction
Scale-up for Next Generation Enzymatic DNA Synthesis (Rosalind)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 3568437.5
EU funding (EUR): 2497906.25
Participants: 1
Project status: CLOSED

DNA Script is a biotech company founded in 2014, developing an enzymatic process for DNA synthesis, i.e. manufacturing DNA. Creating DNA is crucial for R&D in numerous fields of synthetic biology which tackle essential societal issues: climate change thanks to the production of bioproduced materials, healthcare with new biotherapies - especially against cancer, or food security using better strains of plants. Synthesis is also an essential step towards of DNA data storage. All these applications form the long-awaited synthetic biology revolution, and all rely on the capability to efficiently write life code to engineer biological systems. Current DNA synthesis methods are the major bottleneck. The enzymatic process developed by DNA Script, inspired by Nature, aims at improving both speed and efficiency by orders of magnitude. Avoiding the use of toxic reagents, this process will also contribute to a lower environmental footprint for this industry, as well as for its downstream applications. DNA Script’s technological performances in the lab are 3 to 6 months away to overcome current offer. Project Rosalind will accelerate industrial scale-up of DNA Script’s production capability and performances. By developing extensive knowledge in DNA applications and structuring the company’s strategic and commercialization capabilities, Project Rosalind will also help DNA Script go commercial. Enabling technologies such as DNA synthesis have tremendous impact on an ecosystem by accelerating R&D and industrialization cycles of its customer. The project will have a positive impact on the European biotech environment, and potentially trigger the emergence of European biotech leaders. Ultimately, through the numerous applications of synthetic DNA, it will benefit all European citizens.

Keywords: oligonucleotide,nucleic acid,synthetic biology,bioproduction,biosourcing,metabolic engineering,molecular biology,gene editing,genome editing,cell therapy
HIghly advanced Probabilistic design and Enhanced Reliability methods for high-value, cost-efficient offshore WIND (HIPERWIND)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Research and Innovation actions
Countries involved: Ireland,Switzerland,Norway,Norway,France,France,United States,United Kingdom,Denmark
Call: Offshore wind basic science and balance of plant (H2020-LC-SC3-2020-RES-RIA, 2020)
Start date: 2020-12-01
End date: 2024-05-31
Duration (months): 42.0
Total project cost (EUR): 4103638.75
EU funding (EUR): 3999638.75
Participants: 9
Project status: SIGNED

The core challenge addressed in this project is the advancement of the entire modelling chain spanning basic atmospheric physics to advanced engineering design in order to lower uncertainty and risk for large offshore wind farms. The five specific objectives of the HIPERWIND project are to: 1) improve the accuracy and spatial resolution of met-ocean models; 2) develop novel load assessment methods tailored to the dynamics of large offshore fixed bottom and floating wind turbines; 3) develop an efficient reliability computation framework; 4) develop and validate the modelling framework for degradation of offshore wind turbine components due to loads and environment; and 5) prioritize concrete, quantified measures that result in LCOE reduction of at least 9% and market value improvement of 1% for offshore wind energy. The requirements for advanced modelling and development of basic scientific solutions necessitates the strong involvement from academic partners (DTU, ETH, and UiB) and research organizations (IFPEN, DNVGL, and EPRI) and potential end users (EDF) to supply relevant operational data for model validation, provide access to cutting edge industrial environment and to open up exploitation pathways beyond TRL5 toward eventual commercialisation. HIPERWIND employs multi-scale atmospheric flow and ocean modelling, creating a seamless connection between models of phenomena on mesoscale level and those on wind farm level, with the aim of reducing uncertainty in load predictions, and broadening the range of scenarios for which adequate load predictions are possible. Improved modelling of environmental conditions, improved load predictions, better reliability assessment and lower uncertainty, cost efficient design and operating strategies, and lower O&M costs will yield a projected 9% decrease in the Levelized Cost of Energy (LCOE) and 1% increase in the market value of offshore wind by the conclusion of the project.

Keywords: reliability,cost efficiency
Membrane-Free Redox Flow Batteries (MFreeB)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Spain
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-06-01
End date: 2024-11-30
Duration (months): 90.0
Total project cost (EUR): 1998407.01
EU funding (EUR): 1998407.0
Participants: 1
Project status: SIGNED

The environmental concerns over the use of fossil fuels have promoted great interest in generating electric energy from renewable sources such as solar and wind. However, the intermittent nature of those resources demands high performing and cost-effective energy storage systems. Redox Flow Batteries (RFBs) present several advantages, namely, total decoupling of power and energy densities and the possibility of rapid mechanical charging by substituting spent electrolytes with fresh ones. The major issues of the current Vanadium RFBs are the high price and toxicity of vanadium components and the high cost and low performance of the ion-selective membranes they require. MFreeB project proposes to completely remove the problematic membrane of RFBs by developing a disruptive, versatile and scalable concept of Membrane-Free RFB implementing efficient catholytes and anolytes in which the metallic redox pairs are replaced by cheap, abundant and environmental-friendly molecules. In order to achieve this objective, I propose a multi- and interdisciplinary research methodology across a wide range of expertise including fundamental electrochemistry, thermodynamics, physical chemistry, modelling, and mechanical engineering. I will make use of advantages of different electrolytes to develop a versatile concept of Membrane-Free RFB with a wide range of applications. This Consolidator Grant (ERC) would provide adequate support to consolidate my own independent research team and programme. During my scientific career, I have demonstrated creative thinking and excellent capacity to carry out research going beyond the state of the art. My meritorious record of scientific publications (55 ISI articles, h index = 25), project leadership, international collaborations and capacity for supervising and coordinating a research team are presented in the proposal. I am now in an excellent position and research environment to commit and be devoted to this encouraging and challenging project

Keywords: electrochemical energy storage,redox flow batteries,organic redox flow batteries,biphasic systems,redox electrolytes,ionic liquids,organic redox molecules,quinones
Smart Manufacturing for EU Growth and Prosperity (MAKERS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Italy,Italy,Germany,Spain,Germany,Singapore,Switzerland,Sweden,Sweden,Belgium,France,France,United States,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2015, 2015)
Start date: 2016-01-01
End date: 2018-12-31
Duration (months): 36.0
Total project cost (EUR): 1057500.0
EU funding (EUR): 1057500.0
Participants: 20
Project status: CLOSED

MAKERS will bring together leaders from business, academia and policy to study issues related to the drivers and dynamics of sustaining the competitiveness of EU manufacturing sectors. The project’s innovative research, training and mobility activities will address key concerns related to the historic opportunity for the EU to lead a manufacturing renaissance that not only upgrades existing manufacturing competences but, more importantly, develops new technological capabilities across EU regions to support regional industrial resilience for more distributed and sustainable socio-economic growth and prosperity. MAKERS will create a multi-stakeholder platform to discuss the current understanding of issues related to manufacturing renaissance, including (1) the role of small, medium and large manufacturing firms and local production systems plugged into local-global value chains; (2) what are the drivers and processes for innovation, technological capabilities and technology transfer from research intuitions to firms; (3) trends in reshoring and nearshoring and the potentials for re-industrialisation and shorter value chains; (4) the impact of the socio-economic-environmental sustainability agenda on EU competitiveness; (5) skills requirements and training; and finally (6) how policy can ensure the competitiveness of EU manufacturing sectors for more distributed and sustainable socio-economic growth and prosperity. MAKERS’ training programme comprises: 1) annual summer schools that will cover the breadth of the issues above and address methodological requirements; 2) work package-specific Business/Academia/Policy (BAP) workshops; 3) dissemination activities within the network in conjunction with mobility, such as presentations at faculty seminar series, and doctoral level guest lectures; 4) dissemination activities at events outside the network, such as presentations at international conferences, policy fora and multi-media engagement.

Keywords: manufacturing
A Rapid Point-of-Care Breath Ammonia Sensor for Diagnosis of Helicobacter Pylori (AM-SENSE)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: United Kingdom
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-1-2015, 2015)
Start date: 2015-10-01
End date: 2016-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Helicobacter pylori is classified by the World Health Organisation as a carcinogen leading to gastritis and gastric cancer, the second most lethal cancer. The biggest challenge is to identify the infection at an early stage and give a more complete intervention as more than 85% of infections are asymptomatic. This makes screening/ testing an important primary action in combating H. pyrlori and its life threatening effects. Current non-invasive diagnosis methods are based on radiolabelling and are costly, cumbersome to the technician, inappropriate for wide spread clinical use and time consuming in delivering test results. AM-SENSE is a completely new and low-cost hand held electrochemical breathalyser device to efficiently and accurately measure the presence of ammonia in a person's breath to screen for H. pyroli giving ‘instant results’. Costs per test will decrease from an average of €60 to €9.50. The key markets for our product are Europe, Asia and the USA. We project, through manufacturing, retailing and licensing of AM-SENSE a turnover of €59 million in 5 years creating 35 new jobs. A sales forecast of 125,000 units has been set for the 5 year post commercialisation period. This will result in reduced gastric cancer incidence, cheaper and faster treatment for H. pyroli infection and lower all round societal cost. In Phase 1 we intend to test AM-SENSE against gold standards and conduct a more intensified market study, tapping into the knowledge of breathalyser companies through partnerships. In Phase 2 we intend to integrate the electrodes and electronics with the breath capture device into a single market ready prototype and validate with potential clients.

Keywords: breath,test,ammonia,sensor,stomach,cancer,ulcers,helicobacter pylori
Transition towards a more carbon and nutrient efficient agriculture in Europe (Nutri2Cycle)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Research and Innovation actions
Countries involved: Ireland,Italy,Germany,Spain,Spain,Belgium,Poland,Belgium,Belgium,Croatia,Hungary,Hungary,Belgium,France,Netherlands,Netherlands,Denmark,Portugal
Call: Closing loops at farm and regional levels to mitigate GHG emissions and environmental contamination - focus on carbon, nitrogen and phosphorus cycling in agro-ecosystems (H2020-SFS-2017-2, 2017)
Start date: 2018-10-01
End date: 2023-09-30
Duration (months): 60.0
Total project cost (EUR): 7048003.75
EU funding (EUR): 6850050.5
Participants: 21
Project status: SIGNED

NUTRI2CYCLE will use an integrated approach to enable the transition from the current (suboptimal) nutrient household in European agriculture to the next-generation of agronomic practices, characterized by an improved upcycling of nutrients and organic carbon. The project is deeply rooted in pevious national and European projects, in which the consortium members were actively involved. The underlying principle is that Nutrient Use Efficency can be significantly improved by integrating on-farm techniques and systems that allow better reconnection between 1) animal husbandry provided flows and 2) plant production requirements. At the same time this reconnection itself will serve a better C-return to soil and GHG-reduction by avoided emissions optionally combined with energy production for self-consumption on-farm. NUTRI2CYCLE aims to (i) benchmark mass flows of nutrients, organic carbon and GHG-footprint, (ii) provide an assessment frame (toolbox) for evaluating potential impact of proposed innovations, (iii) actively support concepts, techniques and scenarios put forward in EIP-Operational Groups, (iv) optimize these (+ in-consortium developed) scenarios using the toolbox, (v) showcase the most promising developments via prototypes and demos. Finally, using the experience gained at a local/regional scale, NUTRI2CYCLE will elaborate strategic scenarios to identify the effect of these innovations at European scale. NUTRI2CYCLE brings together the extensive expertise of leading experts in the field of nutrient cycling. This collaboration originates from the EIP-Focus Group on Nutrient Recycling, closely interacting with the EIP Operational Groups in the individual EU member states. Better nutrient stewardship engaging all actors across the value chain as envisaged in NUTRI2CYCLE will increase the C, N and P recycling rate significantly and will improve the overall sustainability and innovation capacity of European agricultural systems.

Keywords: ghg abatement,agriculture,nutrient recycling,agro processing,demonstration,soil oc
ERA Chair for Food (By-) Products Valorisation Technologies of the Estonian University of Life Sciences (VALORTECH)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: ERA chairs
Theme: Attracting and mobilising the best talents
Action type: Coordination and support actions
Countries involved: Estonia
Call: ERA Chairs (H2020-WIDESPREAD-03-2017-ERAChairs, 2017)
Start date: 2018-07-01
End date: 2023-12-31
Duration (months): 66.0
Total project cost (EUR): 2498625.0
EU funding (EUR): 2498625.0
Participants: 1
Project status: SIGNED

Advanced food processing technologies, minimum waste and maximum utilisation of raw material used as well as valorisation of by-products constitute a highly relevant range of topics in the EU and worldwide. These are matters that the University of Life Sciences (Eesti Maaülikool, EMU) has been dealing with for long from various angles and perspectives. However, to realise the full potential of EMU in this domain, structural changes are needed to bring various related competences under a unified umbrella as well as to cover several gaps hindering further development. Therefore, the main objective of the current project is to establish a new ERA Chair for Food (By-) Products Valorisation Technologies (VALORTECH), and recruit a top level researcher/research manager (ERA Chair holder) to lead this interdisciplinary, inter-unit entity, formed based on a joint effort by the Institute of Agricultural and Environmental Sciences and the Institute of Veterinary Medicine and Animal Sciences of EMU. The new Chair is expected to considerably improve the research and innovation performance of EMU and conduct forefront research that would create significant benefits for both Estonia, Europe and beyond. Efficient dissemination and exploitation of research results is an issue of key importance in the context of the ERA Chair´s action plan. In addition to targeting the international research community and providing input to policy development, facilitating knowledge transfer to industry is at particular focus. The R&D to be carried out in the VALORTECH Chair is strongly connected with both the national and regional Smart Specialisation strategy, in the context of which efficient use of resources and related development of health-promoting (functional) food are among key priorities. The demand for advanced R&D services in the VALORTECH fields from the side of the industry currently exceeds the capacity of EMU to provide such services.

Keywords: food raw material,by products,valorisation technologies,bioactive compounds,functional food
DELIVERy of advanced therapies for diabetes training network (DELIVER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Ireland,Ireland,Italy,Italy
Call: Innovative Training Networks (H2020-MSCA-ITN-2018, 2018)
Start date: 2019-01-01
End date: 2022-12-31
Duration (months): 48.0
Total project cost (EUR): 1577944.8
EU funding (EUR): 1577944.8
Participants: 7
Project status: CLOSED

The DELIVER EID programme aims to equip 6 industrial PhD graduates with all of the tools required to become creative, entrepreneurial and innovative leaders in the emerging European advanced therapies sector. Advanced therapies are new medicinal products based on genes or cells and tissue engineering products (biomaterials), sometimes used in combination with medical devices. They herald revolutionary treatments for a number of chronic diseases including Alzheimer’s, cancer and the focus of the DELIVER programme, Diabetes Mellitus. We aim to DELIVER the next cohort of translational research scientists in the field of advanced therapies and enabling medical devices for pancreatic islet transplantation, a cell therapy which is poised to become more widespread for the treatment of insulin-dependent diabetes. The DELIVER doctoral training network therefore represents a major interdisciplinary effort between cell biologists, experts in biomaterials, medical devices and advanced drug delivery, clinical experts in islet transplantation and research-active biotech and biomedical companies. Each DELIVER early stage researcher (ESR) will tailor a Personal Career Development Plan (PCDP) to ensure that over the course of the programme the core research skills, advanced research skills and intersectoral transferable skills for a successful career in the advanced therapies sector are acquired. Intersectoral transferable skills training will focus on enhancing career opportunities and employability of the trainees by developing their innovative and entrepreneurial capacity, their communication and leadership skills and their commercial awareness. This will result in graduates with all the skills necessary to innovate, develop and translate advanced therapies for diabetes for the benefit of European patients and industry.

Keywords: type 1 diabetes,innovation,immune protection,angiogenesis