Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Combating Malnutrition in Africa Through Diversification of the Food System (HealthyDiets4Africa)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Germany,Côte d'Ivoire,Belgium,Spain,Nigeria,Mauritius,Kenya,Cameroon,Italy,Denmark,United Kingdom,Bulgaria
Call: AU-EU Combatting all forms of malnutrition (HORIZON-CL6-2022-FARM2FORK-01, 2022)
Start date: 2023-01-01
End date: 2028-12-31
Duration (months): 72.0
Total project cost (EUR): 10822804.0
EU funding (EUR): 10822804.0
Participants: 22
Project status: SIGNED

Various forms of malnutrition, including hunger, micronutrient deficiencies and non-communicable diseases caused by unbalanced nutrition, threaten food security in Africa. The project HealthyDiest4Africa is based on the central hypothesis that diversification of the food system helps to combat all forms of malnutrition while minimizing its environmental footprint. To this aim, we will monitor dietary diversity in eight African countries representing different regions, and develop target group-specific metrics to measure the diversity of the food system and its health outcomes. A production-oriented cluster of the project will explore environmentally sustainable options to diversity food production that specifically address the nutritional requirements identified for the target populations. This includes the development of novel and biofortified crop varieties, utilization of orphan crops with high nutritional value, and diversification of cropping systems and food processing technology. We will link these efforts with a consumption-oriented cluster exploring the consumer acceptance, food safety, and nutritional health effects of diet diversification options. The best solutions that contribute to healthy diets via diversification while also promoting environmental health will be up-scaled via a network of food system stakeholders in eight African countries. HealthyDiets4Africa will also devise communication and policy strategies to maximize outreach and impact of diversified food systems. Thereby the project will help to develop safe, healthy and affordable diets by adopting a diversification strategy that will simultaneously reduce the pressure of food production on the environment.

Keywords: diversity food system underutilized crops cropping systems consumer acceptance,nutritional health
Challenging catalytic routes of hydrogen production from waste plastics (LAUREL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,France
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 2
Project status: CLOSED

Europe and the world are facing to the climate change emergency. To preserve the environment, the ambitious European Green Deal has in the agenda actions related to reducing air, water and soil pollution. In this regard, plastics represent a huge challenge because of they are pollutants that present a recalcitrant nature and consequently widespread and accumulation. Tackling this challenge requires the application of remediation processes beyond than recycle or thermal treatment. Aqueous phase reforming, a mild catalytic process, is here presented as an alternative to eliminate plastics at moderated temperatures and pressures and adding the additional benefit of the production of energetic vectors such as hydrogen or alkanes. To implement this process with high performance, low cost and energy efficiency, photo-oxidation reaction can be employed in a previous treatment. In both stage, the performance of the catalyst is a key aspect. In this context, the general objective of this project is to obtain heterostructured materials for application on complex catalytic process to achieve a clean conversion of plastics to hydrogen. With this aim, this project proposes the synthetic procedures and the physicochemical characterization of heterostructures composed by layered double hydroxides assembled with carbon materials, to get a library of materials with the catalytic properties demanded in photo-oxidation and aqueous phase reforming. The materials will be tested and optimized in the coupled processes over plastics in micronized size, from different nature and composition. The identification of the intermediates is a requirement to understand the mechanism and the catalytic route followed for the pollutants, the especial relevant to demonstrate the potential of this technology to remove and valorize plastics at large scale.

Keywords: aqueous phase reforming,carbon materials
Sharing the Lower Danube During the Cold War (FluidBorder)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-11-03
End date: 2027-11-02
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 1
Project status: SIGNED

FluidBorder investigates the complex history of Romanian-Bulgarian transboundary management of the lower Danube from the establishment of communist regimes until their collapse in 1989. The project is grounded in two key hypotheses: First, it challenges the assumption that ideological alignment within the Eastern Bloc led to uniform river management strategies. Instead, it argues that local political, economic, and environmental conditions shaped each country’s approach to the Danube in unique ways. Second, it suggests that while outwardly cooperative, the management of the Danube often masked underlying tensions and disputes that influenced the balance of power between ideological allies. FluidBorder will pursue three main objectives: 1) Paving the way for a more nuanced understanding of the relationship between communism and the environment, highlighting the numerous factors that shaped environmental conceptions and management strategies in Eastern Europe and the extent to which those factors differed across the region 2) To highlight how the management of natural resources impacted international relations within the Eastern Bloc, adding a new dimension to the international history of communism. 3) To provide a detailed historical account of the lower Danube’s role during the XX century second half, demonstrating how it shaped and was shaped by the evolving relationship between Romania and Bulgaria. Moreover, the project aims to inform contemporary discussions on managing shared natural resources and enhancing collaboration among the countries of the lower Danube’ region, offering lessons relevant to current and future European integration efforts. The river, a crucial geopolitical and economic corridor, remains indeed a key element for the European Union’s southeastern strategy and a vital trade route for Ukraine during the ongoing war.

Keywords: romania,bulgaria,danube,cold war,communism,environment
Haptic sensing skin for biomedical applications with soft magnetorheological elastomers (MagnetoSense)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2022-10-01
End date: 2024-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Sensorial and tacSensorial and tactile information represent the base of all surgical procedures in medicine. The vision sense has been and continues to be developed extensively by use of micro-cameras, MRI, X-rays and many others. Nonetheless, in many cases, the vision is not enough. The touch sense is necessary to identify the stiffness of the underlying organ or tissue and press more or less to perform a cut, remove a tumor or even move a catheter inside a curved vain. This stiffness is transmitted to the finger of the surgeon as a “pressure-deformation” information. This haptic sense is present naturally in our fingertips. Nevertheless, with the recent development of non-invasive techniques, the surgeon operates robotic devices that deliver optical information via a screen but loses all haptic information since his/her fingers are not in direct contact with the organ. The present project aims at proposing a novel material, a magnetorheological elastomer (MRE) membrane as a haptic sensor. MREs are soft elastomeric materials comprising magnetic particles thus being able to deform significantly upon application of an external magnetic field. Recently, it was shown that by fabricating them in exotic or slender geometries one can exploit their resulting instabilities to shape surfaces, induce programmable swelling and deswelling, or even create swimming microrobots and externally controllable catheters. All those applications use MREs as actuators. By contrast, here, we plan to exploit the reverse operation that of sensing, i.e., induce magnetic field changes via deformation. The principle lies in using the inherent magneto-mechanical coupling to induce readable magnetic fields when the MRE deforms. The reading of the fields can then be translated back to a deformation and a force thus being able to sense soft or stiff objects. The very soft nature of MREs will allow for a very sensitive measurement of forces as low as those felt by touching a soft gel or baby-skin.
Prognostic assessment of valvular aortic disease treatment coupling Immunological and biomechanical profiles (PROTEGO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2024-10-01
End date: 2029-09-30
Duration (months): 60.0
Total project cost (EUR): 1498295.0
EU funding (EUR): 1498295.0
Participants: 2
Project status: SIGNED

Aortic valve diseases are degenerative conditions that develop progressively and insidiously. Once symptoms become evident, life expectancy is significantly reduced. While treatments for these pathologies are widely available, there remains a remarkably high rate of procedural complications. These complications have been shown to have a negative impact on cardiac mortality and the likelihood of rehospitalization for heart failure. This underscores the need for further technological advancements. Protego's objective is to determine whether a combination of immunological and biomechanical profiles in patients with aortic valve diseases can effectively predict post-treatment prognosis. My goal is to develop an innovative, validated, and clinically applicable methodology that can identify the best treatment options and predict post-procedural outcomes while minimizing complications. This methodology will serve to determine the timing of treatment for patients with valvular aortic diseases and assess whether the proposed treatment is likely to be beneficial preoperatively, while also minimizing the risk of post-procedural complications. I will achieve this by combining imaging analysis, deep learning algorithms, in silico models, and in vitro tests. My approach involves the following key objectives: (i) creating a multi-physics digital twin of patients with aortic valve diseases, (ii) developing a validated, high-fidelity model for treatment with quantification of post-treatment outcomes and (iii) generating a proof of concept for a clinically applicable predictive model trained using both immunological profiles and biomechanical features of patients. This innovative approach will provide a deeper understanding of how clinical and biomechanical outcomes correlate with the amplification of inflammation, helping us comprehend the interaction between biomarkers and negative post-treatment prognosis in patients with aortic valve diseases.

Keywords: personalised medicine,digital human twin in healthcare,treatment,validation,verification,treatment selection support,aortic valve diseases,transcatheter aortic valve implantation
A transcatheter functional valve replacement for tricuspid valve insufficiency (Trillium)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator Open 2021 (HORIZON-EIC-2021-ACCELERATOROPEN-01, 2021)
Start date: 2022-06-01
End date: 2026-05-31
Duration (months): 48.0
Total project cost (EUR): 5525003.75
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Tricuspid regurgitation (TR) is a cardiac disorder in which the tricuspid valve leaks during systole causing blood backflow, resulting in decreased cardiac output. TR is the most common valvular heart disease affecting 65%-85% of the global population in its mild form. However, mild TR can progress to severe TR, leading to heart failure or death if left untreated. Today, the only option for treatment is valve repair or replacement through open-heart surgery, which is associated with high mortality rates, risks, and costs. Over 3M patients suffer from TR in Europe, and for the majority, their condition is too severe for surgery; therefore, there is no effective treatment. Innoventric has developed the Trillium™ - a transcatheter tricuspid valve replacement solution: the whole procedure is minimally invasive and can be completed in 30mins. Within the EIC project, Innoventric will finalize the clinical validation of its device, ensuring safe and timely intervention for TR patients.

Keywords: tricuspid regurgitation,transdermal implantation,tricuspid valve replacement,implant
Enabling advances in diagnosis, patient stratification and treatment for dilated cardiomyopathy patients and families. (DCM-NEXT)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Germany,Spain,Netherlands,France,United Kingdom
Call: EIC Pathfinder Challenge: Cardiogenomics (HORIZON-EIC-2022-PATHFINDERCHALLENGES-01, 2022)
Start date: 2023-10-01
End date: 2027-09-30
Duration (months): 48.0
Total project cost (EUR): 4137718.75
EU funding (EUR): 4137668.75
Participants: 9
Project status: SIGNED

Dilated Cardiomyopathy (DCM) is a heart muscle disorder characterised by thinning and stretching of the heart ventricles, making it harder for the heart to pump blood (systolic dysfunction). This disorder, with an estimated prevalence of up to 1/250, predominantly affects younger adults. It is associated with significant morbidity and mortality, including heart failure and sudden cardiac death, with end-stage DCM being the leading indication for heart transplantation. The current disease burden in DCM is largely attributable to two important gaps in scientific knowledge: Firstly, our understanding of the aetiology and genetic architecture of DCM remains limited, hindering the utility of genetic testing in clinical patient management. Secondly, there are limited therapeutic options for DCM patients. Existing therapies are generic and target symptoms. No curative treatments exist, apart from invasive heart transplantation and there are no approved therapies targeting underlying molecular disease mechanisms. A fuller understanding of the genetic architecture of DCM and knowledge of the genes and genetic variants involved are critically needed to provide solutions for these unmet medical needs. The DCM-NEXT consortium combines world-leading interdisciplinary expertise and resources of 8 investigators in the fields of DCM, deep clinical phenotyping, cardiogenomics, cardiac transcriptomics, artificial intelligence, in silico drug target discovery and functional studies. They will uniquely leverage their unparalleled cohort of 11,750 DCM probands and relatives with extensive clinical and omics data. Through cutting-edge genomic and cardiac transcriptomic studies, the project aims to (1) revolutionise genetic testing and patient stratification for more precise prediction of disease onset, progression and risk of major adverse cardiac events; and (2) accelerate development of novel therapies by identifying and validating targets involved in pathogenesis of DCM.

Keywords: dilated cardiomyopathy,single cell transcriptomics
A holistic flagship towards the 6G network platform and system, to inspire digital transformation, for the world to act together in meeting needs in society and ecosystems with novel 6G services (Hexa-X-II)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Smart Networks and Services
Action type: Research and Innovation actions
Partnership: SNS (JU-JTI)
Countries involved: Finland,Sweden,France,Germany,Spain,Greece,Belgium,Netherlands,Italy,Denmark,Poland,Austria,Norway,Portugal,Türkiye
Call: 6G Holistic System (HORIZON-JU-SNS-2022, 2022)
Start date: 2023-01-01
End date: 2025-06-30
Duration (months): 30.0
Total project cost (EUR): 25634562.64
EU funding (EUR): 22999795.14
Participants: 48
Project status: SIGNED

To deliver on our European 6G vision for the 2030s, and to tackle opportunities and challenges of increasing magnitude, e.g., sustainability, trustworthiness, green deal efficiency, digital inclusion, there is need for a flagship project, towards the elaboration of a holistic 6G network platform and system. To fill this need, Hexa-X-II is proposed with the ambition of being this flagship project, and of inspiring the world for digital transformation through novel 6G services. Hexa-X-II will work, beyond enabler-oriented research, to optimized systemization, early validation, and proof-of-concept; work will progress from the 6G key enablers that connect the human, physical, and digital worlds, as explored in Hexa-X, to advanced technology readiness levels, including key aspects of modules / protocols / interfaces / data. Hexa-X II includes: (a) the provision of advanced / refined use cases, services, and requirements, ensuring value for society; (b) the delivery of the 6G platform blueprint, which will encompass enhanced connectivity for 6G services, mechanisms realizing the “networks beyond communications” vision (sensing, computing, trustworthy AI), efficient network management schemes; (c) the realization of extended validation at system and component level; (d) actions for global impact, while assuring strategic autonomy in critical areas for the EU. Europe is starting from the pole position with 6G research and is leading wireless network technologies today. Now is the time to leverage our joint research ambition with a flagship project that will lead the R&D effort towards end-to-end systemization and validation. The Hexa-X-II flagship is a unique effort and a holistic vision, of a 6G system of integrated technology enablers, which accomplish “beyond the sum of the parts”, and of a “network beyond communications” platform for disruptive economic / environmental / societal impact; these are vital for establishing the European 6G technology leadership!
Lithium Niobate Quantum systems (LiNQs)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 2499381.0
EU funding (EUR): 2499381.0
Participants: 1
Project status: SIGNED

Quantum technologies are expected to have a transformative impact by exploiting fundamental quantum mechanical effects for technological applications such as quantum computation, quantum simulation, quantum communication, and quantum sensing. Photons are the only reliable qubit for quantum information transmission, making them an essential resource for quantum technologies. However, quantum photonics will only meet its expectation as a ground breaking technology when integrated in a scalable fashion. The solution lies in quantum photonic integrated circuits where photons are used to encode and process quantum information on-chip, offering scalable quantum information processing units. Currently, different integration platforms are investigated with a selection of building blocks available. However, no platform has shown a comprehensive toolbox combining all functionalities on a single chip. In this project I will demonstrate that the thin film lithium niobate on insulator platform can simultaneously link all quantum photonics building blocks on a single platform, resulting in fully integrated quantum photonic integrated circuits. I will develop integrated Lithium Niobate Quantum systems (LiNQs) showcasing the generation, manipulation, and analysis of photonic qubits. This will result in the first compatible integration platform hosting semiconductor quantum emitters, quantum memories based on rare-earth ions, cryogenic electronics, and superconducting single-photon detectors together with the outstanding properties of CMOS-compatible lithium niobate on insulator: low-loss circuits and fast modulators. By developing all required building blocks and linking them to scalable systems, I will provide the quantum technology community a single integration platform for all quantum photonics applications. LiNQs will lay the foundation for Europe’s forefront position in a future photonics-driven quantum technology industry.

Keywords: quantum photonic integrated circuits,quantum technology,lithium niobate on insulator