Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Fluid transport at the nano- and meso- scales : from fundamentals to applications in energy harvesting and desalination process (NanoSOFT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: France
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-04-01
End date: 2021-09-30
Duration (months): 78.0
Total project cost (EUR): 1494000.0
EU funding (EUR): 1494000.0
Participants: 2
Project status: CLOSED

New models of fluid transport are expected to emerge from the confinement of liquids at the nanoscale, where the behaviour of matter strongly departs from common expectations. This is the field of the Nanofluidics : taking inspiration from the solution found by evolved biological systems, new functionalities will emerge from the nanometre scale, with potential applications in ultrafiltration, desalination and energy conversion. Nevertheless, advancing our fundamental understanding of fluid transport on the smallest scales requires mass and ion dynamics to be ultimately characterized across channels with dimensions close to the molecular size. A major challenge for nanofluidics thus lies in building distinct and well-controlled nanochannels, amenable to the systematic exploration of their properties. This project will tackle several complementary challenges. On the first hand the realization of new kind of fluidic devices allowing the study of fluid and ion transport at the nanoscale: these new experimental devices will be obtained by using nanostructures like building blocks as already shown by realising a fluidics set-up based on transmembrane nanotubes; in parallel a dedicated plateform for the characterization of fluid transport will be developed based on electrokinetics and optical detection set-ups. On the other hand, profiting of such experimental set-ups, I will look for the limit of the classical description of the fluid dynamics, focusing on new functionalities emerging from exotic behaviour of fluids at the nanometer level. This will be done by studying different kind of nanofluidics set-up such as carbon and boron-nitride nanotube, ultrathin pierced graphene and h-BN sheet and composite materials. I aim the creation of a link between fundamental research on soft matter and nanoscience-condensed matter with a an attention on the energy production domain, assuring a fruitful transfer between the fundamental findings and new industrial applications.

Keywords: nanofluidics,energy harvesting,blue energy,nanotube,graphene
An advanced and wearable solution to increase motorcyclists’ safety (WOOLF)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Italy
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-12-01
End date: 2018-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Despite legislative and technological progress made over the past 20 years, incidents involving motorcyclists are still cause of concern for the European Union and Member States. The main cause of accidents remains high speed, especially in the presence of specific dangerous road points. The project's aim is to launch, on the European two-wheeled market, the first wearable device able to warn motorcyclists well in advance of the presence of dangerous spots and road sections in which the speed must be carefully controlled. The device, called WOOLF, has been specifically conceived for motorcyclists, developed by exploiting the potential of Internet of Things (IoT) technologies and instant updated road databases. Once on the market, WOOLF will help to dramatically reduce the risk of road accidents for thousands of motorcyclists.

Keywords: motorcyclists safety
Scalable excitonic devices (EXCITE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Switzerland
Call: ERC Proof of Concept Grant (ERC-2019-PoC, 2019)
Start date: 2020-09-01
End date: 2022-02-28
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

EXCITE aims to deliver a key, scalable, industrial manufacturing process that will enable the production of excitonic devices for a wide range of applications. Our innovation can create a new market represented by excitonic devices using 2D materials as energy-efficient interconnects. The demonstration of room-temperature control could open the way to industrial applications of the excitonic device concept, with an excitonic switch and optical modulator being the first types of devices that could be implemented.

Keywords: optoelectronics,optical modulators,excitonic devices
Next generation algorithms for grabbing and exploiting symmetry (ENGAGES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Germany,Germany
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-03-01
End date: 2025-02-28
Duration (months): 72.0
Total project cost (EUR): 1999094.0
EU funding (EUR): 1645758.66
Participants: 2
Project status: SIGNED

Symmetry is a phenomenon that appears in many different contexts. Algorithmic symmetry detection and exploitation is the concept of finding intrinsic symmetries of a given object and then using these symmetries to our advantage. Application areas of algorithmic symmetry detection and exploitation range from convolutional neural networks in machine learning to computer graphics, chemical data bases and beyond. In contrast to this widespread use, our understanding of the theoretical foundation (namely the graph isomorphism problem) is incomplete and current algorithmic symmetry tools are inadequate for big data applications. Hence, EngageS addresses these key challenges in the field using a systematic approach to the theory and practice of symmetry detection. It thereby also fixes the existing lack of interplay between theory and practice, which is part of the problem. EngageS' main aims are to tackle the classical and descriptive complexity of the graph isomorphism problem and to design the next generation of symmetry detection algorithms. As key ideas to resolve the complexity, EngageS offers three new approaches on how to prove lower bounds and a new method to settle the descriptive complexity. EngageS will also develop practical symmetry detection algorithms for big data, exploiting parallelism and memory hierarchies of modern machines, and will introduce the concept of and a road map to exploiting absence of symmetry. Overall EngageS will establish a comprehensive software library that will serve as a platform for integrated research on the algorithmic treatment of symmetry. In summary, EngageS will develop fast, efficient and accessible symmetry detection tools that will be used to solve complex algorithmic problems in a range of fields including combinatorial algorithms, generation problems, and canonization.

Keywords: algorithmic symmetry detection and exploitation,the graph isomorphism problem,interplay between theory and practice
personalised Diabetes Management using lOw-cost Needle-free multiple-biomarkers monitoring Device (DiaMOND)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Belgium
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2018-07-01
End date: 2021-06-30
Duration (months): 36.0
Total project cost (EUR): 4519408.75
EU funding (EUR): 2493273.13
Participants: 1
Project status: CLOSED

"Diabetes is the #1 health challenge of the 21st century. Continuous Glucose Monitoring or CGM ($1.25B market in 2016, growing 29%/yr) is today’s cornerstone of “diabetes self-management” and the most effective solution to reduce the economic and societal burden of diabetes. But the shortcomings of current CGMs hinder their wider adoption: high cost, unsatisfactory predictability of severe events, and poor user comfort. The DiaMOND project will remove these barriers by bringing needle-free, low-cost Continuous Diabetes Monitoring to market. DiaMOND is specifically geared at extending Indigo’s current CGM with reliable severe clinical event prediction and a great user experience; demonstrating the reliability in a first-in-man trial; creating market acceptance by involving Key Opinion Leaders; and obtaining reimbursement. Indigo will be ready for a large pivotal clinical study and CE marking after completing the DiaMOND project. DiaMOND will accelerate Indigo’s CDM market access by 2-3 years."

Keywords: continuous diabetes monitor,personalised diabetes self management,multi biomarker sensor
Development of a Compact, Time-Efficient and Safe Medical Diagnostics Machine (Origin)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2019)
Start date: 2020-04-01
End date: 2023-09-30
Duration (months): 42.0
Total project cost (EUR): 3939037.5
EU funding (EUR): 1975712.38
Participants: 1
Project status: SUSPENDED

Current tissue processors on the market take up to 24 hours to process samples for diagnosis and leave the operator exposed to chemicals. They also use different kinds of chemicals, in large volumes, which leads to cross contamination of chemicals and samples. This results in more plastic packaging to dispose of, making the process both costly and environmental unfriendly. Our company, DIAPATH SpA, is developing an innovative solution to these problems, Origin. DIAPATH has been in the tissue processing industry since 1997 and currently has a turnover of €16.8 Million and 97 employees. Origin reduces the number of processing steps, and reduces the number of chemicals used. The operator will be safeguarded from chemical exposure. Our value proposition is, less operating costs due to reduced chemicals and packaging, faster diagnosis and results for patients. Our target users are Hospitals and Diagnostics Laboratories. The current global diagnostics market is estimated at €243.59 Million and expected to reach €378 Million by year 2025. Our entry point for our innovation will be the European market, where we already have significant market share. We will be using our extensive distribution chain to bring our innovation to international markets. Our innovation is currently at prototype stage with a compact functional machine tested in relevant environment. Further validation and tests remain to be done to bring it to market. This innovation will grow our market share to 30% and increase our turnover to €60million by 2023. It will also create 29 new jobs.

Keywords: cancer diagnostics,tissue processor,diagnostic machine,histopathology,laboratory diagnostics,human tissue,tissue fixative,pathology
Active role of skeletal muscle extracellular matrix in muscular dystrophies (DYSTROPHIC-ECM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-07-01
End date: 2025-03-31
Duration (months): 36.0
Total project cost (EUR): 295061.76
EU funding (EUR): 295061.76
Participants: 1
Project status: CLOSED

Most of the muscular dystrophies (MDs) are due to defects the trans-membrane protein complex called Dystro-Glycan Complex, which is a structural and functional bridge between myofiber contractile apparatus and extracellular matrix (ECM).MD research is focused upon the cellular mechanisms of the pathology and there is a lack of information about how ECM molecules can affect MDs, although alteration in ECM composition is acknowledged since fibrosis is an important bad outcome in the patients.Our hypothesis is that alterations in dystrophic muscle ECM directly account for mechanisms which negatively affect skeletal muscle homeostasis.The goal of the project is to identify alterations in ECM compromised by muscular dystrophy and to investigate their effects on cell behavior.Mdx mouse (model for Duchenne Muscular Dystrophy) and Sarcoglycan-β-null mouse (model for Limb Girdle Muscular Dystrophy 2E) will be used.To obtain the ECMs we will take advantage of decellularization approach that removes the cellular components while maintaining the molecular and structural features as closer as possible to the native ECM.In tissue engineering the use of ECM biomaterials demonstrated that ECM plays a fundamental, active role in tissue remodeling by growth factors release and ECM degradation product action.Molecular alterations in the ECM composition will be investigated by proteomics that assures an accurate and exhaustive characterization.ECM will be used as 3D environment to study its functions in the behavior of primary cells involved in the pathology: myogenic stem cells, endothelial cells, fibro-adipogenic precursors and macrophages.Discovering how alterations in dystrophic muscle ECM affect myogenesis, angiogenesis, fibrosis and inflammatory response will be of paramount importance for a better understanding of MDs.Changing the focus of the research from the cells to the ECM, this study will provide a new point of view and could contribute to identify new therapeutic targets.

Keywords: extracellular matrix,skeletal muscle,muscular dystrophies,decellularization,proteomics
Thermoacoustic- based residential mCHP system (eTAG)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Israel
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2014, 2014)
Start date: 2015-03-01
End date: 2015-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The eTAG (embedded ThermoAcoustic Generator) includes a novel electricity- generating thermoacoustic engine, embedded inside an existing residential boiler, to form a renewable and economic micro Combined Heat and Power (mCHP) system, without any hot moving parts. The proposed synergetic approach results with a sustainable system, taking full advantage of alternative fuels value to produce regulated electrical power as well as domestic heating, at overall energy efficiency above 90%. To enable a cost effective application, the embedded electricity generating unit must be highly reliable and maintenance free, thus a thermoacoustically based solution is expected to be the ideal solution. Qnergy has recently demonstrated 1 kW solar thermoacoustic application. However, the optimal configuration and combined system spec must be refined for best market acceptance, according to consumer’s needs and budget limitations. In common situations, a typical user will experience an ROI of less than two years; though specific government policies may lead to different optimal power capacities, as net metering allows using an oversized alternator and feedback the grid in excessive electricity. Thus our planned feasibility assessment will include a thorough business plan, focusing on market needs, time to market, and identifying the main customers and competitors; resulting in a measurable product specification and detailed risk management plan. Additionally, the key factors affecting overall system performance will be identified according to the thermo-acoustic-electrical simulation and the detailed design model. Moreover, a full freedom to operate IP survey will be performed, while the product cost, manufacturing technologies and its limitations will be covered. During phase 1 broad market understanding would be sought, allowing to better select the content and schedule of the following phase 2, focusing mostly on particular techniques for lowering the $/W value of the full system.

Keywords: thermoacoustics,tase,stirling,mchp,boiler
Radiocarbon constraints for models of C cycling in terrestrial ecosystems: from process understanding to global benchmarking (14Constraint)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Germany,United States
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-12-01
End date: 2022-11-30
Duration (months): 72.0
Total project cost (EUR): 2283747.0
EU funding (EUR): 1853872.0
Participants: 2
Project status: CLOSED

The overall goal of 14Constraint is to enhance the availability and use of radiocarbon data as constraints for process-based understanding of the age distribution of carbon in and respired by soils and ecosystems. Carbon enters ecosystems by a single process, photosynthesis. It returns by a range of processes that depend on plant allocation and turnover, the efficiency and rate of litter decomposition and the mechanisms stabilizing C in soils. Thus the age distribution of respired CO2 and the age of C residing in plants, litter and soils are diagnostic properties of ecosystems that provide key constraints for testing carbon cycle models. Radiocarbon, especially the transit of ‘bomb’ 14C created in the 1960s, is a powerful tool for tracing C exchange on decadal to centennial timescales. 14Constraint will assemble a global database of existing radiocarbon data (WP1) and demonstrate how they can constrain and test ecosystem carbon cycle models. WP2 will fill data gaps and add new data from sites in key biomes that have ancillary data sufficient to construct belowground C and 14C budgets. These detailed investigations will focus on the role of time lags caused in necromass and fine roots, as well as the dynamics of deep soil C. Spatial extrapolation beyond the WP2 sites will require sampling along global gradients designed to explore the relative roles of mineralogy, vegetation and climate on the age of C in and respired from soil (WP3). Products of this 14Constraint will include the first publicly available global synthesis of terrestrial 14C data, and will add over 5000 new measurements. This project is urgently needed before atmospheric 14C levels decline to below 1950 levels as expected in the next decade.
High performing batteries for accelerated uptake of hybrid and electric vehicles (BATTERY PLUS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Spain
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-01-01
End date: 2018-05-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Air pollution derived from transport is a major problem for cities in Europe and worldwide. Traffic congestion already stifles about 2% of the global GDP each year and this negative trend is set to continue due to the exponential growth of urban population. Hybrid and Electric vehicles (H&EVs) are a key component of the overall transport solution. However e-mobility still presents many drawbacks, the main ones being the price and range of electric vehicles which are reliant on optimal battery technologies. The BATTERY+ project aims to bring into the market the next generation of high performing Li-ion battery solutions for e-mobility that goes beyond the existing state-of-the art. This claim is sustained by: its proven energy density (leading to more range and less weight); the most accurate State-of-Charge monitoring system (reducing users’ anxiety for sudden changes in range); and the support of an advanced remote system for remote battery monitoring, diagnosis and driving advice. The batteries will be on average 30% more durable, leading to significant cost-efficiencies for both EV manufacturers as well as end-users. Initially targeting Light Electric Vehicles (LEVs) and Heavy Duty Electric Vehicles (HDEVs), in time, the technology has the potential to be deployed in electric vehicles of all sizes as well as in any battery-powered appliances. The company behind the project is MILLOR, a young SME specialised in the design, development and manufacturing of high added value battery solutions. In just a few years of existence, the company has managed to position itself as a key innovator in battery technology in Spain and has also tied links with key partners in Europe and Asia. The management of the company sees the BATTERY+ project as its springboard to accelerate its growth.

Keywords: batteries,e mobility,electric vehicles,light electric vehicles,heavy duty electric vehicles,urban mobility,motorcycles,li ion battery