Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Instability and COntrol of MAssively SEparated Flows (ICOMASEF)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain,United Kingdom
Call:  (FP7-PEOPLE-2009-IRSES, 2009)
Start date: 2011-01-01
End date: 2014-12-31
Duration (months): 48.0
Total project cost (EUR): 216000.0
EU funding (EUR): 216000.0
Participants: 2
Project status: CLOSED

Flow separation determines the quality of environmental and biological flows alike. Large-scale separation on lifting surfaces, such as aircraft wings and wind-turbine blades, is a phenomenon of key technological significance, since it determines the performance characteristics of the surfaces involved. In addition, flow separation is a major contributor to aerodynamic noise generation. Analysis, computation and experimentation may all be used to identify physical mechanisms related with both hydrodynamic and aeroacoustic small-amplitude instabilities related with flow separation. Such linear perturbations may then be exploited in the context of theoretically-founded (active or passive) flow control at a rather small enegry input. Of equal significance is the noise-reduction possibilities offered by precise knowledge of the noise generation mechanisms. The proposed action brings together leading scientists in the fields of theoretical, computational and experimental fluid mechanics, whose past work has made substantial contributions to the present understanding of separated flow instability and flow control. The respective groups have access to world-class computational or experimental facilities and an interest in pursuing a coordinated effort in a jointly-defined common direction. The consortium comprises nine PIs and their respective groups from five nations: 2 EU MCs (2), Australia (2), Brazil (2) and India (3). The capacities of the EU partners are predominantly theoretical/computational, while the non-EU groups have demonstrated strengths in both computation and experiment. In the course of the present action, short-duration visits of senior personnel as well as longer-term stays of junior researchers have been planned, with a twofold aim: knowledge-sharing and experience interchange amongst the senior personnel, as well as broadening of career perspectives through acquisition of new skills by the younger researchers

Keywords: aerodynamics,flow control computational fluid dynamics (flight physics),aircraft external noise
CIliates as NAtural Reservoir of potentially PATHOgenic BACTERia: an ecological, functional and evolutionary genomic investigation (CINAR PATHOBACTER)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy,Germany,France,Germany
Call:  (FP7-PEOPLE-2009-IRSES, 2009)
Start date: 2011-05-20
End date: 2015-05-19
Duration (months): 48.0
Total project cost (EUR): 469900.0
EU funding (EUR): 433800.0
Participants: 5
Project status: CLOSED

In the last years, Protists (Protozoa) gained a significant attention from the scientific community because of their role as Trojan horses respect to opportunistic pathogens of humans and animals. Although this role is nowadays well established and accepted for some Protists like Acanthamoeba, little is known for other groups of possible hosts. Recently, members of the coordinating unit of Pisa got evidences that many of the natural occurring bacterial symbionts of ciliates have a strong phylogenetic affiliation to human and animal (especially fish) pathogens like Rickettsia (Vannini et al., 2005; Ferrantini et al., 2009; Ferrantini et al., in prep) and Francisella (Schrallhammer et al., in prep.). These observations raised the question whether ciliates may also represent natural reservoirs for potentially pathogenic bacteria especially in tropical regions where the environmental conditions favor microbial growth and fast evolution. Furthermore tropical countries are predicted as the Hot Spot for emerging infectious diseases and zoonosis due to hygienic standards lower than in Western countries and the living together of humans with their farmed animals. Aim of the present project is to set up an international research network that, starting from the collection of novel isolates especially from tropical regions, performs a complete ecological, functional and evolutionary genomic investigation on symbiotic bacteria retrieved from ciliates that shows phylogenetic affinities to pathogenic ones. Units from the proposed network posses expertise that ranges from the traditional morphological investigation to advanced ultrastructure, ecology, functional biology, molecular phylogeny, comparative genomics and postgenomics. Aim of the research network will be to coordinate the research activities of the involved units into joined projects and to transfer know-how to the younger researcher to allow them to re-establish the acquired competences in their home laboratories.

Keywords: bacterial pathogens of animals,zoonesis,phylogeny,evolutionary biology,genomics,protozoology,bacteriology,molecular markers and recognition,monoclonal antibodies,taxonomy,symbiosis,ciliates
Exploiting the best sensory modality for learning arithmetic and geometrical concepts based on multisensory interactive Information and Communication Technologies and serious games (weDRAW)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Ireland,Italy,Italy,Greece,France,United Kingdom,United Kingdom
Call: Technologies for Learning and Skills (H2020-ICT-2016-1, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 2454616.25
EU funding (EUR): 2454616.25
Participants: 9
Project status: CLOSED

The weDRAW project comes from the renewed neuroscientific understanding of the role of communication between sensory modalities during development: specific sensory systems have specific roles to learn specific concepts. Starting from these results, in weDRAW we will develop an multisensory technology and three serious games that will exploit the best modality for learning arithmetic and geometrical concepts. In particular weDRAW: - will provide the elements to the teacher to determine which is the best modality (visual, audio or haptic) to teach each specific concepts to the students; - will provide the technology to exploit the best sensory signal; - will permit to teach different concepts together. This will be possible by using a multisensory approach, that will open a new teaching/learning channel, personalized for each student, based on multisensory interactive technology (i.e., audio, tactile, motor and visual), including a serious game platform. - will show that it is possible to learn arithmetical concepts from multisensory rhythm exploration and music and geometrical concepts from body movement and multisensory drawing. - will permit a “deeper learning of Science and Mathematics combined with Arts” improving creative capacities of learners. Besides application to typical children, a major goal and output of this project consists of applying the proposed multisensory approach and technologies to two specific populations: visually impaired and dyslexic children. In particular, dyslexic children have problems with rhythm, whereas visually impaired children have problems with space and geometry. With weDRAW we expect to improve the spatial and temporal impairments of these two groups of children braking down social barriers.

Keywords: multisensory development,arithmetic,geometry,music,drawing,serious games,social interaction,multi sensory technology,embodiment,affective computing
In Vivo Single-Cell Mechanomics of Bone Adaptation and Regeneration in the Aging Mouse (MechAGE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-10-01
End date: 2023-03-31
Duration (months): 66.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Osteoporosis, one of the most prevalent degenerative diseases, is characterized by a reduction in bone mass and increased fracture risk and has been partly attributed to the decrease in mechanical usage of the skeleton. A detailed understanding of the molecular mechanisms governing load-regulated bone remodeling could therefore lead to the identification of molecular targets for the development of novel therapies. Bone remodeling is a multiscale process mediated through complex interactions between multiple cell types and their local 3D environments. However, the underlying mechanisms of how cells respond to mechanical signals are still unclear. By combining single-cell “omics” technologies with well-established tissue-scale models of bone mechanobiology, MechAGE proposes to develop the technology required to allow spatially resolved in vivo single-cell mechanomics of bone adaptation and regeneration. CRISPR/Cas technology will be exploited to generate fluorescent reporter mice to identify the different cell types involved in the bone remodeling process. By combining RNA-sequencing of single cells isolated by laser-capture microdissection with micro-finite element analysis and time-lapsed in vivo micro-CT, MechAGE will link the transcriptome of hundreds of single cells to their local mechanical in vivo environment (LivE). This will allow investigation of molecular responses of the cells to LivE changes with aging in established mouse models of bone adaptation and regeneration. In addition to in vivo mechanomics, MechAGE proposes to use cellular and multiscale computational modeling to run in silico simulations of real-world events for better understanding of diseases of aging in mice and to maximize the use of the high quality in vivo mechanomic data. Findings from MechAGE will lead to a systems level understanding of the spatio-temporal regulation of gene expression during the process of load-induced bone adaptation and regeneration in the aging mouse.

Keywords: bone,osteoporosis,fracture,mechanobiology,biomechanics,tissue engineering,regenerative medicine,omics,micro computed tomography,imaging,computational modeling,cell,adaptation,regeneration
The ghostworker's well-being: An integrative framework (GHOSTWORK)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 1958490.0
EU funding (EUR): 1958490.0
Participants: 1
Project status: SIGNED

Artificial intelligence depends on human labour to conduct tasks such as data cleaning, coding, and classifying content. This on-demand work is offered and performed online, paid by the task, on platforms like Amazon Mechanical Turk. Conceptualized as ‘ghost work’, this rapidly growing, platform-based work is largely unseen: workers are unable to speak with managers, do not get feedback, and lack labour protections. How do these specific work conditions influence ghost workers’ well-being? To ensure decent work conditions as automation continues to expand, knowledge about the effects of ghost work on well-being is urgently needed. The proposed project will develop and test an integrative framework for analysing the effects of ghost work on worker’s well-being. Existing models for analysing the impact of work conditions on well-being fall short for studying ghost work, as these models assume a person has a job and most likely an employer and colleagues. Therefore, this project begins from the specificities of ghost work to synthesize theories and concepts about algorithmic control, occupational well-being, human computation, and platform labour, in order to understand how and through which mechanisms ghost work influences well-being. The project will contribute to and advance cross-disciplinary scholarship on platform labour and organizational studies of algorithmic technologies. Using a multi-methodological approach to study the effects of ghost work, it begins with in-depth interview-based fieldwork on ghostworkers’ work conditions, and then entails qualitative diary studies of the short-term dynamics of ghost work for worker’s work conditions and well-being. Finally, a 4-wave longitudinal panel study will investigate the relationship between ghost work and well-being over time. Scholars in multiple fields, as well as policy makers and industry leaders, will be keenly interested in both the resulting integrative framework and empirical findings.

Keywords: platform work,platform labour,digital labour,workers well being,work conditions,algorithmic control,job control,algorithmic fairness,employee well being
Building Self-Sustaining Research and Innovation Ecosystems in Europe through Responsible Research and Innovation (SeeRRI)

Framework: Horizon 2020 — Science with and for Society
Programme: Integrate society in science and innovation issues, policies and activities in order to integrate citizens' interests and values and to increase the quality, relevance, social acceptability and sustainability of research and innovation outcomes in various fields of activity from social innovation to areas such as biotechnology and nanotechnology
Action type: Coordination and support actions
Countries involved: Austria,Spain,Italy,Israel,Austria,Spain,Austria,Norway,Norway
Call: Supporting the development of territorial Responsible Research and Innovation (H2020-SwafS-2018-1, 2018)
Start date: 2019-01-01
End date: 2021-10-31
Duration (months): 34.0
Total project cost (EUR): 2031612.5
EU funding (EUR): 2031612.5
Participants: 12
Project status: CLOSED

SeeRRI establishes a foundation for building self-sustaining R&I ecosystems in Europe by developing a framework for integrating RRI approach into regional development policies in 3 European territories: B30 Area (ES), Polymer and Mechatronic Cluster (AU), and Nordland Region (NO). To self-sustain, SeeRRI ecosystem will be “healthy”, i.e. adaptive, resilient, reproducible, continuous learning, and open or closed when needed. With 12 quadruple-helix partners from government authorities, clusters and SMEs, academics, and civil organization, SeeRRI will build an integrated framework based on literature review and co-creation with the relevant stakeholders. By mapping the territorial R&I ecosystem, SeeRRI will understand the supporting conditions for R&I and identify the stakeholders that will be involved to formulate a variety of scenarios for building a self-sustaining ecosystem in their territories. The engaged stakeholders will gain awareness and insights while engaging in creative collaboration using workshops and open-labs, thus will function as multipliers and promote RRI principles in their territories and beyond. The input from stakeholders will contribute to defining and validating a framework for self-sustaining R&I ecosystems developed by the project team, which will generate concrete activities to be implemented. Furthermore, SeeRRI will evaluate the activities carried out in the pilot territories and assess their impact at EU level, thus offering concrete guidelines for policies, suggesting conditions and governance structures for the R&I ecosystems with a roadmap tool identifying RRI openings in Smart Specialisation process. Finally, SeeRRI will establish a Network of Affiliated Territories, i.e. other territories with a composition that could mirror SeeRRI ecosystem, to help contribute, improve, and apply SeeRRI framework. Learning and best practices will be transferred across territories. This will facilitate its scaling-up at European and global level.

Keywords: smart specialisation,regional development policy,co creation,governance innovation,innovation ecosystems
Consensual Non-Monogamies and Social Movements: A Comparative Study of Activism in Portugal and the UK (CNM-MOVES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2021-12-01
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

This research project focuses on the transnational comparative analysis of the similarities, differences, and connections between social movements that focus on Consensual Non-Monogamies (CNMs), both in Portugal and in the UK, with an emphasis on polyamory. It will consider how this political theme is taken up in different contexts, and how those contexts impact social movements, how they influence one another (via the geographical circulation of cultural products, activists, ideas and affects), how different macro- and micro-political strategies develop and interconnect with other social movements, and how they become enmeshed with the media representations produced about and by those groups. It focuses on the mediatization of intimate citizenship, as well as the history of activism and the interaction among social movements in Europe, and fills a gap in the extant literature on CNMs and sexual politics, opening up new understandings for Human Rights, citizenship, social and legal justice. The project takes into consideration the gendered, racial, sexual and classed aspects of political engagement and visibility, as well as the fluid definition of what is considered “political”. Funding for this project will allow the Experienced Researcher (ER) to considerably increase his academic and employability profile by advancing his position as a leading expert on CNM-related research in Europe; by improving his publication record in English; by allowing him to expand his areas of expertise into Political Theory, Sociology, Law, as well as reinforcing his expertise on gender and sexualities; by diversifying his methodological portfolio and allowing him to receive media, academic writing and PhD supervision training. MMU, the host institution, would benefit from diversifying its academic backgrounds, increase its international connections with other Higher Education Institutions, as well as its solidifying its role in the field of CNM-related research.

Keywords: social movements,politics,media,consensual nonmonogamy,polyamory,citizenship,portugal,comparison
Air pollution, antenatal depression and anxiety, and foetus brain development (PRESSURE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-04-01
End date: 2023-03-31
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: CLOSED

Latest research suggests a link between air pollution (AP) and psychological health, including depression and impaired neurodevelopment. In pregnant women, besides mother’s own well-being, antenatal anxiety or depression may result in an abnormal brain development of the offspring generation. However, little evidence is yet available on these fields. Traditionally, epidemiological studies have used modelled ambient AP estimates at home, with biases arising from this simplification. Personal measurements of AP permit the determination of accurate exposure and dose, by considering different environments and physical activity intensities. Moreover, previous studies lack the assessment of possible confounding by noise on the effects of AP. The aims of the PRESSURE Project are to assess the effect of air pollution and noise in mother’s antenatal depression and anxiety and to evaluate the mediation role of mother’s depression/anxiety in the link between AP and the development of brain structures in the foetus. To achieve this aim, (i) I will develop a modelling framework to accurately quantify the exposure and dose of the population to PM2.5, Black Carbon (BC), and NO2 in different time-windows of the pregnancy period by using data from personal measurements in a large cohort of pregnant women (n=1,300); (ii) I will assess the effect of AP and noise exposure/dose on antenatal depression and anxiety (evaluated through questionnaires); and (iii) I will evaluate the mediation role of antenatal anxiety/depression in the association between maternal exposure to AP and structural changes in the growing brain of the foetuses and new-borns through neuroimaging (transvaginal neurosonography and neonatal MRI). This multidisciplinary project may add insight in the fields of exposure assessment and AP effects on mental health and brain development, and may lead to public health actions to improve air quality and reduce the burden of disease associated with air pollution in Europe.

Keywords: cohort,pregnant women,air pollution,anxiety,depression,brain development