Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
European Centre of Excellence for Engineering Applications on HPC and associated technplogies (EXCELLERAT P2)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: European High Performance Computing
Action type: Research and Innovation actions
Partnership: EUROHPC (JU-JTI)
Countries involved: Germany,France,Italy,Slovenia,Sweden,Spain
Call: Centres of Excellence for supporting supercomputing applications for Science and Innovation (HORIZON-EUROHPC-JU-2021-COE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 5972988.75
EU funding (EUR): 2986494.0
Participants: 16
Project status: SIGNED

EXCELLERAT P2 continues the fruitful partnership of Europe’s leading HPC centres, application specialists and supporting partners who have worked with and offered their expertise and knowledge to engineering companies and researchers from across industry and academia for the past three decades. A key strength of EXCELLERAT P2 is that it will build on the achievements of EXCELLERAT P1, including the available service portal as a baseline for impact and awareness creation. Furthermore, the critical mass, knowledge and expertise of Europe is re-united and extended by additional experts, to continue the Centre of Excellence, which will span the whole domain of engineering – ensuring that innovations produced are applicable to other engineering challenges, that co-design is handled properly, that success stories are created and distributed, all in all to support best the European HPC strategy. EXCELLERAT P2 will base its evolution and developments on six chosen use cases, requiring the full range of HPC usage profiles, from small scale capacity type applications, all the way to hero run type large scale applications. The advancements the use cases as well as further applications will make beyond the state of the art, as well as the results, which will be derived by the execution of the use cases and the further applications, will have a clear impact in Europe. EXCELLERAT P2 (and the brand) strives to show the contribution of HPC, HPDA and AI in engineering to a low-carbon, more environmentally friendly and socially responsible product development and manufacturing as well as the mobility and energy sector. The holistic view of EXCELLERAT P2 to the usage of HPC (and HPDA and AI) is needed, if engineering applications shall be supported to increase the European competitiveness. Thus, the developments done in EXCELLERAT P2 will increase the European competitiveness in HPC-applications, hardware-design and HPC-service provisioning to a new level.

Keywords: centre of excellence,engineering,eurohpc,exascale,high performance computing,artificial intelligence,data analytisc
Empowering Personalized Therapeutics: Advancing 3D-Nano DLD Arrays and Raman Micro-Biochips for Precision Isolation, Segmentation, and Molecular Profiling of Exosomal Trop2 Biomarkers in TNBC (ExoDiagAI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany,Poland
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-16
End date: 2026-09-15
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 2
Project status: SIGNED

The ExoDiagAI project is at the forefront of addressing a critical challenge in modern healthcare—early diagnosis and effective management of breast cancer, particularly the aggressive and elusive triple-negative breast cancer (TNBC) subtype. TNBC lacks well-defined molecular targets, hindering treatment options. Exosomes, a subset of extracellular vesicles with unique functions, hold great promise as diagnostic and prognostic markers for various diseases, including cancer. These tiny vesicles are abundant in biological fluids but have been underutilized due to the absence of a cost-effective isolation protocol. Our primary goal is to develop a microfluidic device, integrating nano-lateral displacement arrays with a Raman biochip, to identify exosome biomarkers specific to TNBC and translate this knowledge into clinical practice. This project's main objectives encompass creating the microfluidic device, assessing its surface-enhanced Raman spectroscopy (SERS) capabilities, conducting Raman fingerprinting of exosomes from in vitro cell cultures and patient samples, and employing chemometric analysis to discriminate biomarkers. The distinctive Raman fingerprinting associated with exosomes serves as a promising prognostic and diagnostic marker. By introducing 3D printing SERS technology, we aim to enable real-time monitoring, shedding light on exosome structural integrity. This interdisciplinary project combines organic, inorganic, nano, computational, spectroscopic, and molecular biology techniques, culminating in innovative device fabrication. Ultimately, the ExoDiagAI project holds the potential to revolutionize early breast cancer diagnosis through exosomal biomarkers, aligning with the EU's sustainable development strategy for advanced diagnostic platforms and fostering the career of a promising researcher. This endeavor marks a pivotal step towards enhancing the detection and management of TNBC, addressing a pressing healthcare need.

Keywords: 3d nano dld arrays raman micro biochips exosomal trop2 biomarkers triple negative breast cancer tnbc personalized medicine
Innovative Organic Fruit Breeding and uses (InnOBreed)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Innovation actions
Countries involved: Italy,France,Belgium,Germany,Spain,Czechia,Denmark,Austria,Greece,Switzerland
Call: Fostering organic crop breeding (HORIZON-CL6-2021-BIODIV-01, 2021)
Start date: 2022-07-01
End date: 2026-06-30
Duration (months): 48.0
Total project cost (EUR): 4965151.25
EU funding (EUR): 4790326.0
Participants: 21
Project status: SIGNED

The Organic fruit sector is highly dependent on inputs, particularly in terms of plant protection. Climate change is increasing impacts and risks to organic fruit production. Large market demand is expanding for organic fruits but the current commercial cultivars (cvs) range previously selected in high input paradigm are, for most of them, not adapted to organic production. InnOBreed proposes to mobilise Innovative Solutions (ISs): social innovations, new ideotypes, new methods for screening robust cvs and genitors with larger genetic bases for fostering organic fruit breeding. These ISs will be targeted and developed on participative, multi-actor and multi-trait based approaches and then applied for evaluating underutilized Fruit Tree Genetic Resources (FTGR), pre-breeding and advanced material. InnOBreed’s scope encompasses many Rosaceous species but also citrus and grape. InnOBreed aims to improve the whole Fruit chain through the implementation of an Organic Variety Testing Network of actors. It deals with (i)identification and definition of current lock-in in organic fruit farming systems (OFS),(ii) co-designing new ideotypes fitting with local OFS,(iii)identification of performant IS already available, (iv)development of new climate change ISs but also for fruit quality, pests and diseases tolerance, low input fitness and robustness, and their application by FTGR curators,(v) IS’s validation process and implementation by several public-private case-studies in different regions for evaluating their efficiency , and (vi)checking sustainability and consistency with actual regulations before being disseminated for maximizing IS impacts on the value chain.InnOBreed is deeply connected with running initiatives, programmes and resources involved in OFS, organic fruit participative and classical breeding, fostering FTGR uses by fruit-chain, scientists and stakeholders. Particular attention will be paid to embed the relevant stakeholders at national and European levels.

Keywords: fruit organic agriculture,multi actor,multi trait,resilience,participative,fruit genetic resources,management,conservation,evaluation,phenology,climate change,pests and diseases,quality
Industrial Wood: European Industrialisation as Seen from the Forests (1870-1914) (INWOOD)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1489901.0
EU funding (EUR): 1489901.0
Participants: 1
Project status: SIGNED

INWOOD studies industrialisation through the most important pre-industrial resource: wood. Scholarship on industrialisation has concentrated on the introduction and spread of new energy sources and materials, paying scant attention to the pre-existing resources. However, available data shows that wood was fundamental in the key sectors driving industrialisation, while its consumption increased during this process. INWOOD analyses the role that wood played during industrialisation and the impact of industrialisation on the actors and sectors most involved in wood use, with a focus on Europe during the first globalisation (1870-1914). Inspired by current debates on ecological crisis and energy transition, the project pioneers an interdisciplinary and multi-scale approach to analyse the links between the following interrelated issues: Economic dynamics on a macro scale: the changes in wood consumption in relation to industrial demands, but also the spread of alternative energy sources and materials; the transformation triggered by industrial technology in the geography of wood flows and in the logistics of the wood supply chain. Social dynamics on a micro scale: the impact of changes in the wood economy on the populations living close to the woodlands, in both the areas that were central before industrialisation and those that became central because of it; the choices made by actors involved in the exploitation of woodlands when faced with these developments. Ecological dynamics on multiple scales: the evolution of the European forest cover in terms of reforestation in some regions and deforestation in others; the main qualitative changes in the forest landscape in terms of tree species composition, age and density. INWOOD integrates sources and analytical methods to change the way scholars understand industrialisation and to provide the historical context for present-day debate about the role of forests in climate change mitigation and biodiversity preservation.

Keywords: environmental history history of energy timber frontier forest transition
Women Tech Europe Support Scheme (Women TechEU)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Interconnected Innovation Ecosystems
Destination: Interconnected Innovation Ecosystems
Action type: Coordination and support actions
Countries involved: Spain,Italy,Austria,Malta,Belgium,Ireland,France,Netherlands
Call: Organisation of the Women TechEU Scheme (HORIZON-EIE-2023-CONNECT-01, 2023)
Start date: 2024-02-01
End date: 2026-05-31
Duration (months): 28.0
Total project cost (EUR): 15000000.0
EU funding (EUR): 15000000.0
Participants: 15
Project status: SIGNED

Entrepreneurship is crucial for economic growth and societal progress, yet women remain underrepresented in the field, accounting for less than a third of entrepreneurs in EU. This under-representation not only highlights inequality but also limits EU's potential to tackle pressing challenges, such as the digital, green, resilience transition, and recovery from the pandemic. Deep tech sectors are even less balanced, and investment for women-led companies remains less than 2% of the total To address this gender gap, Women TechEU will bridge collaboration between the European Commission and pan-European deep tech women-led startups to create a more gender-balanced entrepreneurship ecosystem. Built on the exisisting foundations of the EIC Women TechEU initiative, our consortium will scale this iniatiative with a clear perspective towards long-term sustainability We will invest 12M€ in equity-free grants to 160 women-led deep tech companies and additional support services in a programme enhancing current EIC BAS to which we will link The consortium is comprised by partners covering all the expertise and geographies needed to reach over 15000 women entrepreneurs in deep tech from all over Europe. Led by EIT Manufacturing, it is strengthened with the participation of other KICs from EIT like Health, Food and Climate, leveraging the power of their network and landmark events. We also count with the expertise from Sploro in cascade funding programmes. Across Limits will guide the communication and dissemination activities as well as link in the service delivery with Awaken Hub, who will coordinate an effort to evaluate over 1500 experts in 4 different open calls. The consortium is complemented by major networks of investors and women entrepreneurs like EBAN, AFAEMME, or FI Values and purpose driven we will search for sustainability and major impact of the initiative during the project and beyond even proposing a PPP structure to further exploit the project results.

Keywords: deep tech,women led deep tech companies
FREquency comb SpectrosCOpy using Specialty optical fibers (FRESCOS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-02
End date: 2026-09-01
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

Nonlinear fiber optics is paving the way for a new paradigm of technological developments, especially in the domain of modern communication, computation and metrology. Project FRESCOS (FREquency comb SpectrosCOpy with Specialty optical fibers) will utilize nonlinear optical effects in an interdisciplinary setting, harnessing the untapped potential of specially designed optical fibers for developing a simple-architecture all-fiber multi-comb spectroscopy setup. This innovative and breakthrough technology will be used to perfrom dual and tri-comb spectroscopy for precise and rapid chemical sensing as well as the study of transient nonlinear response of samples in the 1.5 micron wavelength, that are inaccessible to linear spectroscopic techniques. The required nonlinear specialty optical fibers, like tri-core fiber, tri-mode fiber, polarization maintaining fiber (with and without twisting) and dispersion compensating fiber will be designed and fabricated during the project in the fiber fabrication facility (FiberTech Lille) at the host institute. Project FRESCOS will capitalize on a unique blend of scientific disciplines starting from fiber fabrication, nonlinear optics, chemical physics, to spectroscopy, to achieve a milestone in the science of precision spectroscopy and generate results to deepen our understanding of the fundamental physics of energy levels in chemical molecules.

Keywords: spectroscopy,optical frequency comb,optical fiber
Peer Learning of Innovation Agencies for Services of Access to Finance for Innovative SMEs (AccesSME)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Estonia,Greece,Lithuania
Call: Peer learning of innovation agencies (H2020-INNOSUP-05-2016-2017, 2016)
Start date: 2017-06-01
End date: 2017-11-30
Duration (months): 6.0
Total project cost (EUR): 50000.0
EU funding (EUR): 50000.0
Participants: 3
Project status: CLOSED

Innovative SMEs are most likely to create new markets, achieve rapid growth, and help the economy recover. External finance may be particularly important for innovative SMEs, as they usually lack the internal resources to successfully commercialise innovations. However, innovative SMEs often find it the hardest to obtain finance because they tend to have riskier business models, which are important to create new markets but are also difficult for banks to value. Innovative SMEs are often more reliant on intangible assets, rather than physical property, but intangibles are difficult to value as they are context specific, and thus hard to use as collateral for lending. AccesSME project is dedicated to contribute tackling this issue. The objective of the project is to enable the participating innovation agencies to cooperate in a tangible and cost-effective manner so as to improve existing or create new concepts, methodologies and tools for SMEs on access to finance through mutual learning and exchange of good practices. The project aims to cover three kinds of access to finance options: 1) Business to business (B2B) matching for partnerships and investments 2) Horizon 2020 SME Instrument 3) crowdfunding platforms.

Keywords: access to finance,innovation support,innovative sme
Supporting Causal Conclusions from Observational Survival Studies (SCOUT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-10-01
End date: 2020-09-30
Duration (months): 24.0
Total project cost (EUR): 166156.8
EU funding (EUR): 166156.8
Participants: 1
Project status: CLOSED

The focus of my proposal is on statistical mediation analysis in medical studies with patient survival as outcome. Mediation analysis can help to elucidate the underlying mechanisms and ultimately to alter and further improve components of an intervention or shift the target of an intervention. Specifically, in aim 1 we utilize penalized likelihood techniques in an innovative way to improve mediation analysis with sparse data, e.g. rare side effects of drugs. Aim 2 will focus on the Aalen additive hazards model, an alternative to the Cox proportional hazards model, in particular when causal inference and mediation is of primary interest. We will consider a series of case studies comparing Aalen additive hazards model with the Cox proportional hazards model regarding interpretability of effect estimates, ease of application, applicability of assumptions, ease of description in an interdisciplinary context and public perception. By means of analytical reasoning and empirical studies we fill important gaps in knowledge, while the interdisciplinary working environment and intersectoral seminars will ensure that the achieved advances reach the relevant stakeholders. During the secondment at the Novartis Statistical Methodology Group in Basel, I will get in touch with mediation analysis for interventions in clinical trials and its connections to the estimands framework, which is currently being considered a promising alternative to the intention-to-treat paradigm as first principle in evaluating effects of interventions. The suggested action will combine my supervisor's and my scientific expertise and international experience at its best and thus guarantees mutual growth. Interaction with a highly active research group, participation in the institutional programme for soft skill development and involvement in project administration will further contribute to my development towards independence and are important prerequisites for various career paths.

Keywords: causal inference,direct and indirect effects,sparse data,survival analysis
Centre of Excellence for Advanced Technologies in Sustainable Agriculture and Food Security (ANTARES)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Framework Partnership Agreement
Countries involved: Serbia,Serbia,Netherlands
Call: Teaming (H2020-WIDESPREAD-2014-1, 2014)
Start date: 2015-05-04
End date: 2020-05-03
Duration (months): 60.0
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 4
Project status: CLOSED

Agriculture and food security are one of the main focal points of EU policies, since,in the next 20 years, world food production must increase by 50%, while 80% of that increase must come from intensification (Source: FAO). ANTARES aims to evolve BioSense Centre at the University of Novi Sad, Serbia, into a European Centre of Excellence (CoE) for advanced technologies in sustainable agriculture and food security. This endeavor is supported by the participation of the Serbian Ministry of Education, Science and Technological Development (MESTD), the national research authority who will provide both institutional and legislative expertise as well as co-financing of 14 mil Euro. The participation of DLO, the Netherlands, the leading European research institute for applied and market-driven research in agriculture and food security, currently involved in 250 FP7 projects, will secure that the know-how and experience of highest European standards are transplanted to Serbia. ANTARES envisages a long-term and mutually beneficial strategic cooperation between DLO and the new CoE, by exploiting the competitive advantages of both organizations. The project relies on the principles of continuity (by capitalizing on the achievements of BioSense), evolution (by identifying the gaps and implementing actions to address them), and consensus (by incorporating the needs and expectations of stakeholders in the vision and strategy of the new CoE), to engage the region in a path of innovative growth. ANTARES is perfectly aligned with the regional innovation priorities as presented in the Smart Specialization Strategy of Vojvodina, while its impact in innovation, economic development, and sustainability is expected to spread at a much broader national and European level.

Keywords: centre of excellence,advanced ict technologies,sustainable agriculture,food security