Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Multimodal Optimisation leveraging Data Acquisition from Local Stakeholders towards a Holistic Improvement of Freight and people Transport (MODALSHIFT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Safe, Resilient Transport and Smart Mobility services for passengers and goods
Action type: Research and Innovation actions
Countries involved: Spain,Portugal,Austria,France,Italy,Belgium,Bulgaria,Canada
Call: Optimising multimodal network and traffic management, harnessing data from infrastructures, mobility of passengers and freight transport (HORIZON-CL5-2024-D6-01, 2024)
Start date: 2025-06-01
End date: 2028-11-30
Duration (months): 42.0
Total project cost (EUR): 4999373.75
EU funding (EUR): 4999373.25
Participants: 17
Project status: SIGNED

The vision of MODALSHIFT lies in the creation of a transport network and traffic management optimisation framework, trusted and valuable for local stakeholders, that bridges the data from infrastructures, logistics and mobility operators. New IoT devices - a smart box enabling Capacity-as-a-Service, and a e-subscription device for public transport access for vulnerable people, will increase the sources for data collection. A mobility data space, associated to novel geolocation data anonymisation, will be set up in the 3 Case Studies (Bulgaria, Italy, Spain) to ensure trusted and secure data exchange between data providers and users. This multisource data will enhance traffic state forecasting and increase the detection rate of events by 15%. On this basis, predictive and prescriptive analytics and synchromodality-based scenarios, tested in digital twins and early pilots, will identify optimal actions of transport stakeholders for adjusting their operations, towards a reduction of 25% of the interconnection or transshipment delays. Agent-based modelling will identify how a modal shift towards low-carbon, active and shared mobility services can be acceptable by end-users and support a reshape of the public transport services and the use of urban space. A multimodal traffic management platform will orchestrate, upon the data space, the cooperation of stakeholders at network and multimodal hub scales. It enables the connection of dynamic optimisation algorithms to operational drivers’ tool for mobility operators, and of static models to visual interface for transport planners. The determination of governance models, values for each stakeholder, dynamic pricing and business models, will steer the participation of 8 stakeholders for each Case Study in the multimodal traffic management system. With this approach, MODALSHIFT stimulates new uses of the transport network to reduce traffic congestion for low-carbon and inclusive mobility, avoiding pernicious rebound effects.

Keywords: multimodality,capacity as a service,optimisation,logistics,public transport,digital twin,data space,multimodal traffic management,agent based modelling,collaboration,dynamic pricing
KNOW-HOW: A new framework for theoretical and practical control across intelligence domains (KNOW-HOW)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2025-10-01
End date: 2030-09-30
Duration (months): 60.0
Total project cost (EUR): 2480625.0
EU funding (EUR): 2480625.0
Participants: 1
Project status: SIGNED

Knowing what is true is valuable, but practical knowledge – knowledge how to do things – is equally critical. Having such ‘know-how’ enables us to succeed in action, and achieve our goals. Currently, little consensus exists across philosophical and empirical disciplines about the nature of know-how and what is involved in exercising it. Research results are siloed across epistemology, action theory, philosophy of language, and cognitive science, and fundamental disagreement persists about whether research questions about know-how primarily concern cognitive processes or behavioral manifestations. These theoretical barriers hinder our ability to recognize and utilize know-how effectively. KNOW-HOW aims to make a major advance here by developing a comprehensive framework for understanding know-how and its place in a wider web of concepts we rely on to understand and describe intelligent behavior across a range of activities we care about and depend on. A novel hypothesis to be explored is that know-how disposes us not just to success but to creditworthy control. This control, it is proposed, takes a theoretically unified form in both intentional action and judgment, revealing how know-how enhances performance in a structurally symmetrical way when we deliberate and when we act. With minimal metaphysical commitments, the framework applies to both biological and artificial intelligence, avoiding ad hoc explanations and preserving theoretical unification across areas of philosophy that have yet to benefit from each other's shared resources. KNOW-HOW will put our understanding of know-how on a new footing, impacting academic research across disciplines.

Keywords: virtue epistemology know how intentional action practical knowledge action theory epistemology of know how epistemic normativity
Omni-factory for end-to-end apparel automation (O-factory)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 21.0
Total project cost (EUR): 2120000.0
EU funding (EUR): 2120000.0
Participants: 1
Project status: SIGNED

Global apparel production exceeds 150 billion garments/year, with 45 billion unsold. The Global Apparel Industry releases 1.2 billion tons of CO2 and consumes 93 trillion litres of water annually, resulting in financial losses of > €468 billion/year due to inventory distortion. Consumer demands shifting faster than new clothes can be made and delivered is a problem, especially because most clothing is often produced far from where it is consumed. Microfactories offer a promising solution for transforming the apparel manufacturing landscape. Automation is a vital ingredient for microfactories to be profitable in countries where labour costs are higher. However, their full potential is yet to be realized due to technology gaps and business models hindering a wider adoption. Rodinia is developing the O-factory: ground-breaking software & hardware for onshore, on-demand and order-activated apparel manufacturing. O-factory stands out for being the first full-scale end-to-end microfactory technology; its comprehensive automation level and agnostic integration capabilities with SoA technologies are based on Rodinia’s innovative cloud-based operations software & hardware which makes custom garments in 48 h (Just-in-time), ensuring that production matches sales; reducing garment cost by up to 14% compared to traditional manufacturing while quantifying the environmental impact of each product made; emphasising ultra flexibility and scalability. This project will support optimisation of key technological aspects of the automated O-factory: its omni-operations software, the ‘brain’ of the system, and the custom-engineered equipment it controls; the O-factory’s automation-enabling ‘body parts’. It will also support setting up a full-scale operational unit demonstrating the seamless automated workflow and enhancing marketing & commercialisation efforts. EIC support will create high-skilled jobs and contribute to reaching global sustainability targets on CO2 and water reductions.

Keywords: automation,end to end microfactory,apparel industry,onshore,just in time,cost efficient garments,environmental impact data,sustainability,overproduction free,robotics,advanced algorithms
StromaForte - breakthrough biological treatment for Acute Respiratory Distress Syndrome (ARDS) (StromaForte)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 36.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

StromaBio is developing StromaForte, a Mesenchymal Stromal Cell (MSC)-based therapy for Acute Respiratory Distress Syndrome (ARDS) patients requiring Extracorporeal Membrane Oxygenation (ECMO). ARDS is a severe lung condition affecting 166,000 people in the EU and 3 million worldwide each year. It often leads to multiple organ failure and necessitates intensive care, presenting a significant healthcare challenge exacerbated by the COVID-19 pandemic. The mortality among hospitalised patients can even surpass 60% in most severe cases. The yearly cost of ECMO, which is a last resort treatment for ARDS patients used in critical cases, can reach up to $200,000 for a single patient. StromaForte represents an innovative approach utilising the regenerative and anti-inflammatory properties of MSCs to mitigate the underlying causes of ARDS, offering a potential cure rather than alleviating its symptoms. A key milestone was in 2015 when two ARDS patients on ECMO were treated on a compassionate-use basis and fully recovered. In the ongoing Phase I/IIa trial the endpoints were met and the preliminary results have confirmed the safety and efficacy of StromaForte. StromaBio is the sole provider in Europe of a therapeutic solution that has demonstrated efficacy in the treatment of ARDS patients on ECMO and holds the patent for this designation. With the support of the EIC Accelerator, we plan to run the Phase IIb study, which will allow us to achieve conditional market approval in the EU (via the PRIME scheme) and start selling to clinics across Europe in 2027. This project aligns with the EU's innovation and healthcare enhancement goals. Its successful development and deployment of StromaForte will position Europe at the forefront of regenerative medicine and advanced ARDS treatments, showcasing the EU's commitment to healthcare innovation and patient care.

Keywords: stem cell therapy,mesenchymal stromal cells,biological drug,acute respiratory distress syndrome,ecmo
Abortion in European Mainstream News Media: A Feminist Critical Socio-Cognitive Discourse Study (DARE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Lithuania
Call: ERA Fellowships (HORIZON-WIDERA-2024-TALENTS-02, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 181136.16
EU funding (EUR): 181136.16
Participants: 1
Project status: SIGNED

The debate over the access to sexual and reproductive health and rights has been going on for centuries. In Europe, the right to bodily autonomy has been included in the EU Fundamental Rights Charter very recently, in April 2024. This decision has taken place in a context where social and political landscapes remain divided between those who support and those who oppose free, safe, and legal access to abortion. Given that the news is a major source of information for citizens and influences public opinion and attitudes, Project DARE aims to critically examine how the polarisation surrounding the abortion debate has been discursively manifested in contemporary European mainstream news media discourse. DARE is characterised by an interdisciplinary approach that integrates quantitative corpus-based methods with qualitative discourse analysis to study the polarising discourse strategies used to conceptualise abortion and its related social actors in four major European news websites. As a feminist critical socio-cognitive study, DARE will take into account the potential influence of the context, ideological and gender biases, discrimination, and stigma in the reproduction of polarising discourses and attitudes towards abortion. DARE will be the first interdisciplinary project to compile and critically analyse a corpus of news articles on abortion published during the pandemic and post-pandemic period (2020-2025). Through this work, DARE aims to fulfil its overarching feminist goals of normalising abortion and advocating for reproductive justice in contemporary society. By addressing the timely issues of health and well-being, and gender equality, DARE will contribute to constructing a resilient, inclusive, and democratic European society, in line with the United Nations Sustainable Development Goals and the Horizon Europe 2023/2024 Programme.

Keywords: abortion polarisation news media discourse bias feminist critical discourse analysis socio cognitive discourse studies
Proximity Network Assay: driving the future of high-resolution protein interactomics in 3D for precision medicine, drug discovery, and molecular diagnostics (PNA)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator Open 2025 (HORIZON-EIC-2025-ACCELERATOR-02, 2025)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 3571427.14
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Pixelgen Technologies, a deep-tech Swedish life sciences company, pioneers innovation in spatial proteomics and interactomics, critical for precision medicine, cancer research, and drug discovery. Building on the success of its Molecular Pixelation (MPX) technology, Pixelgen introduces the Proximity Network Assay (PNA), enabling high-resolution, high-throughput protein mapping. The PNA technology addresses current limitations in spatial proteomics and interactomics:low resolution, scalability challenges, and high costs of traditional microscopy-dependent methods. PNA technology employs a unique DNA-based approach, achieving an unprecedented 30 nm resolution and multiplexing over 150 targeted protein markers in a single assay. Diseases are caused by aberrant cell function. These functions are executed by protein interactome dynamics, currently not studied at scale. PNA will allow researchers to assay intricate protein interactions at both cellular and subcellular levels (including cell-to-cell interactions and FFPE tissues), unlocking insights into immune responses, drug mechanisms, and disease pathology. PNA eliminates the need for expensive and low-content optical imaging systems, providing a cost-effective and accessible solution for academic and industrial applications. PNA is currently at TRL6, with proof-of-concept data generated for key use cases. The EIC Accelerator project aims to develop PNA to TRL9 by advancing reagent development, creating optimised sample preparation protocols for FFPE tissues and cell-to-cell interaction studies, and enhancing data processing software for seamless integration with multi-omics platforms. PNA technology will redefine spatial proteomics, enabling groundbreaking research and fostering Europe’s leadership in the biotechnology sector. The project aligns with the EU’s priorities in healthcare and digital transformation, contributing to the European Health Union’s goals of advancing diagnostics and personalised treatment.

Keywords: spatial proteomics,protein interactomics,intracellular protein mapping,high resolution proteomics,optics free 3d protein localisation,dna based spatial mapping,protein interaction networks
OMEGA: The autonomous organic weeding robot (OMEGA)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Greece
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 36.0
Total project cost (EUR): 2100000.0
EU funding (EUR): 2100000.0
Participants: 1
Project status: SIGNED

In modern agriculture, the persistent challenge of weed infestation poses a significant threat to crop quality and yield, resulting in substantial economic losses and environmental degradation. Current methods of weed management often involve labour-intensive practices, over-reliance on chemical herbicides, and limited precision, exacerbating these issues. However, Terra Robotics presents a groundbreaking solution with OMEGA, an autonomous laser weeding robot that revolutionizes weed control in agriculture. By integrating cutting-edge technologies such as advanced robotics, AI-driven algorithms, and precision laser technology, OMEGA offers a comprehensive and sustainable approach to weed management. OMEGA operates autonomously, navigating crop fields with precision and efficiency, while its AI-driven weed detection algorithm identifies and targets weeds with unparalleled accuracy. The precision laser weeding system of OMEGA achieves a remarkable weed elimination accuracy exceeding 95%, while concurrently reducing chemical herbicide usage by 70%, thereby minimizing environmental contamination. Additionally, it enhances soil health by preventing compaction and increasing soil organic matter by 20% over three years, leading to healthier and more abundant harvests. OMEGA delivers substantial cost savings by halving labour expenses and reducing long-term operational costs related to fuel and equipment maintenance by 30%. Furthermore, it provides farmers with data-driven insights for real-time monitoring of crop health and soil conditions, potentially boosting farm productivity by 10%. With customizable service packages for diverse customer segments, Terra Robotics' OMEGA offers a transformative solution that addresses critical challenges in modern agriculture, promoting sustainability and efficiency.

Keywords: laser weeding,soil health management,gps technology,sustainable agriculture,environmental protection
Bank deposit token hubs for cross border payments (DTH)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 18.0
Total project cost (EUR): 2450558.0
EU funding (EUR): 2450558.0
Participants: 1
Project status: SIGNED

Cross-border financial transactions such as corporate international payments are problematic using the existing conventional financial infrastructures. They are slow, expensive and inefficient, with smaller companies being more severely impacted and only the large multinational companies getting access to state-of-the art, global financial services at competitive prices. Additionally, any failed transactions result in the entire process being restarted, compounding associated problems. This represents a significant waste of time and financial resources on a global scale. Project DTH will deliver a universal deposit token solution based on enterprise grade blockchain technology for the use of commercial banks, which will offer a feasible and vital solution to the multiple problems posed by existing systems for cross-border payments and liquidity management. The bespoke technology will be deployed at clients’ premises or deployed as Software as a Service (SaaS). The project aims to enable real-time visibility and control of tokenized liquidity for banks allowing them to save tens of millions in liquidity costs annually, and to develop corporate treasury and payments services for their clients that work in real time, on a 24/7 basis, with full transparency and traceability, without errors and with increased efficiency. This will result in a transparent, secure, timely and cost-effective solution for banks and their clients that will revolutionize existing processes for cross-border payments and intraday liquidity management.

Keywords: corporate international digital payments,digital assets,deposit tokens,tokenized deposits and money,liquidity management,real time payments,transaction banking services,saas,cloud computing
SEcuring doMestic PRoduction of cost-Effective BIOmethane (SEMPRE-BIO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Spain,Germany,Denmark,Norway,France,Belgium,Netherlands
Call: Innovative biomethane production as an energy carrier and a fuel (HORIZON-CL5-2021-D3-03, 2021)
Start date: 2022-11-01
End date: 2026-04-30
Duration (months): 42.0
Total project cost (EUR): 11753080.0
EU funding (EUR): 9852707.75
Participants: 17
Project status: SIGNED

SEMPRE-BIO aims to demonstrate novel and cost-effective biomethane production solutions and pathways, deemed essential to achieve the European Green Deal and climate and energy targets for 2030 and the net zero greenhouse gas emissions by 2050, and to increase the market up-take of biomethane related technologies. To that extent, SEMPRE-BIO will set up three European Biomethane Innovation Ecosystems (EBIEs), based in Baix Llobregat (ES), Bourges (FR) and Adinkerke (BE), which are representative of the different baseline situations for biomethane production across Europe Those initial EBIEs will facilitate long-term replication, by creating an active flow of information and resources for ideas to transform into reality. Through the EBIEs, SEMPRE-BIO will build a process by which more innovators and entrepreneurs will be able develop and launch solutions to solve problems related to the larger-scale and cheaper production of biomethane, faster. This process will create new technical expertise, helping to diversify the technology portfolio, and will allows businesses to better know their potential customers. Additionally, EBIEs will provide the means to create economic stability and resource sharing. The value of EBIEs lies in the access to resources for the start-ups and the flow of information for the ecosystem’s stakeholders. This information flow will create more future investment opportunities for the right institutions to connect with the right ideas for their businesses and portfolios, at the right time, for the right reasons. Overall, the challenge is to decrease investment and operational costs, to optimize feedstock supply, use, identify alternative feedstock as well as reduce their costs, to improve plant efficiency and operations, to factor in the carbon savings and to increase and monetize co-benefits, such as from the commercialization of the digestate or the valorization of residual gas streams.

Keywords: biomethane,upgrading,methanation,syngas,cryo separation,co2 valorization,green deal,innovation ecosystems