Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The Family at War in French Culture, 1870-1914 (FAMWAR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-09-01
End date: 2023-05-31
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: SIGNED

FAMWAR investigates how the familial experience of the Franco-Prussian War of 1870-71 was represented in the cultural production of the first four and a half decades of the Third Republic. The years 2014-18 have seen a vast reflection on the European experience of the First World War. One of the most successful aspects of this has been the way more traditional military and diplomatic history has dovetailed with the modern concerns of cultural, social and gender history. It is the aim of FAMWAR to apply these insights to what might be termed "the war before the First World War", namely the Franco-Prussian War. Fought almost exclusively on French soil, the war was a traumatic experience for France, not just politically (with the fall of Napoleon III's Second Empire; the birth of the Third Republic in September 1870, which would last until the Second World War; and the civil war of the Paris Commune in 1871), but also socially (in the two sieges of Paris, and in the battlefield experience and its effects on the provincial population). Wars, we know from the twentieth-century experience of two world wars, involve on all sides the mass separation, damage and reconfiguration of families; and in particular, the shifting of gender relations in and beyond the family. It is precisely the intensity of the twentieth-century European experience of war which has turned 1870-71 into what has been called "the forgotten war". Yet 1870-71 represents a key foundational moment in the invention of modern Europe (when France finally embraced republicanism for good, and Germany was born as a nation-state). How, we shall ask, was the family's experience of this war remembered in literature, journalism and iconography? It is the aim of the current project to correct that oversight, not least as the 150th anniversary of the war approaches, and not least because it is the experience of the Franco-Prussian War which French and German people carried, within living memory, into war in 1914.

Keywords: zola,nineteenth century french literature,the novel,franco prussian war,1870 71,french third republic,family,press,visual culture,neuville,detaille
ADVANCED NEXT GENERATION LANDING SYSTEM (ANGELS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Italy,Italy
Call: Small business innovation research for Transport (H2020-SMEINST-2-2015, 2015)
Start date: 2015-12-01
End date: 2017-10-31
Duration (months): 23.0
Total project cost (EUR): 2318163.75
EU funding (EUR): 1622714.63
Participants: 2
Project status: CLOSED

ANGELS is a high precision instrumental guidance system at the price of an optical guidance system. ANGELS makes use of standards and context aware customizable predictive software to dramatically increase the level of safety in Approach & Landing (A&L) operations. ANGELS focuses in a very specific scenario: Helicopters A&L operations to helidecks at wind farms and Oil/Gas (O/G) rigs (our primary market), where poor visibility (optical guidance systems don’t help), complex glide paths (non straight line approaches), high density of obstacles and reduced space are a constant, and where decision makers (usually helidecks constructors and helicopter service companies) are very sensitive to price (small companies), who need affordable instrumental guidance solutions to comply with requirements from platforms managers.

Keywords: instrumental guidance system,guidance,ads b,aandl,gbaas,offshore platforms,helicopter
SemAntically integrating Genomics with Electronic health records for Cancer CARE (SAGE-CARE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Ireland,Germany,Greece,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2014-12-01
End date: 2018-11-30
Duration (months): 48.0
Total project cost (EUR): 450000.0
EU funding (EUR): 450000.0
Participants: 5
Project status: CLOSED

The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to create a holistic informatics platform for rapidly integrating genomic sequences, electronic health records (EHRs) and research repositories to enable personalised medicine strategies for malignant melanoma treatment. The consortium has engaged in a pre-proposal process with active clinical end users who have highlighted the need for more innovative approaches for the treatment of cancer - in particular the treatment of malignant melanoma, including inter alia the ability to rapidly query of geno-phenotype associations in melanoma such as the recently discovered rs2301641 SNP variability with ABCB5 function and CDK4 gene indicators . Hence we aim to develop a scalable HPC framework that allows the semantic interlinking between spatially distributed electronic patients’ health records, associated genomic sequences and published research, thereby allowing clinicians to make reasoned queries over vast knowledge bases for the diagnosis, treatment and management of malignant melanoma.

Keywords: gene ontologies,semantic integration,scalable bioinformatics
Stem Cell-Derived Exosomes for the treatment of Traumatic and Degenerative Eye Disease (EXO-EYE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United States,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-06-01
End date: 2020-05-31
Duration (months): 36.0
Total project cost (EUR): 269857.8
EU funding (EUR): 269857.8
Participants: 2
Project status: CLOSED

The death and dysfunction of retinal ganglion cells (RGC) is a major cause of blindness in traumatic and degenerative ocular disease. For example, 60M people are affected by glaucoma with 4.5M becoming blind in both eyes, whilst optic neuritis affects 5/100,000 people and represents a significant problem for sufferers. RGC are the sole projection neurons and their axons make up the optic nerve, making them exquisitely sensitive to injury. As CNS neurons are irreplaceable, neuroprotective strategies are paramount to therapies aimed at preserving vision but as of yet, no such therapy exists. Current research has demonstrated significant neuroprotection by mesenchymal stem cells (MSC) including those from the bone marrow (BMSC), acting not as replacements for RGC but rather, as paracrine-mediated support cells. Clinical trials are already ongoing to test their efficacy in patients. Despite this, the exact mechanism behind their neuroprotective potential is not well understood. Recent studies have shown that exosomes, extracellular vesicles containing proteins, mRNA and miRNA may mediate much of the paracrine support offered by MSC and thus act as an easily purifiable cell-free alternative therapy for RGC neuroprotection. This proposal aims to assess the therapeutic efficacy of BMSC-derived exosomes, their characterisation and that of their RNA cargo. We will test these exosomes in animal models of traumatic (optic nerve crush) and degenerative (glaucoma) eye disease. Specifically, this proposal employs a novel strategy to promote RGC survival (relevant to ONC and glaucoma) and axon regeneration (relevant to optic nerve crush) through the use of exosomal delivery of mRNA/miRNA into injured RGC utilizing in vitro and in vivo injury models, RNAseq and CRISPR technology.

Keywords: neuroprotection,retinal neurons,optic nerve regeneration,glaucoma,mesenchymal stem cells
Innovative fungal strains for producing blue cheeses (BLUE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-09-01
End date: 2019-02-28
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The ERC project GenomeFun has revealed a substantial genetic and phenotypic variability within Penicillium roqueforti, which is the fungus used for the maturation of blue cheeses. The ERC project GenomeFun has also shown the existence of different genetic clusters harboring specific traits and has allowed the development of a protocol for inducing in the laboratory the natural process of sexual reproduction in this fungus. The present PoC BLUE project aims at proving the possibility to obtain and identify, in sexual progeny, strains of P. roqueforti with novel combinations of traits of industrial interest. This would enable strain improvement, and would allow the production of blue cheeses with innovative characteristics, as desired by producers and consumers. Thus the objective of the present PoC project is to identify progeny with interesting combinations of traits. These strains will then be protected and commercialized. The project therefore also aims at identifying the market and the best strategy for exploitation, firstly by defining the most suited approach for the protection and exploitation of intellectual property, taking into account the market practices and conditions, and secondly, by verifying the legal dispositions applicable to sexual progeny of micro-organisms in the field of “novel food”, biodiversity and genetic resources protection. The legislative framework raises interesting questions in the context of recent treaties on biodiversity. The consequences of the recent laws on biodiversity on the use and protection of micro-organisms as intellectual property in the fields of food are still unclear. The results of these investigations could thus serve as a model case.

Keywords: food,cheese,fungal strains
Sustainable PRactices of INteGration (SPRING)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Inclusive societies
Action type: Coordination and support actions
Countries involved: Austria,Austria,Italy,Belgium,Romania,Netherlands,Canada
Call: Sustainable practices for the integration of newly arrived migrants into societies (H2020-SC6-MIGRATION-2020, 2020)
Start date: 2021-03-01
End date: 2023-02-28
Duration (months): 24.0
Total project cost (EUR): 2108434.39
EU funding (EUR): 1999536.25
Participants: 10
Project status: CLOSED

SPRING will develop a toolbox to improve the innovation, effectiveness and sustainability of the work done by Europe’s integration stakeholders at national, regional and local levels. The SPRING consortium brings together some of Europe’s most well-connected integration researchers, think-tanks and stakeholder networks. Mobilizing their significant research, networks and communications capacities, the SPRING partners will identify and engage with the main researchers and communities of practice on integration: national and local policymakers and public sector, NGOs, business and grassroots initiatives (i.e. local volunteers, migrant leaders, and religious groups). These communities will shape the project’s activities through piloted participatory techniques for needs assessments, co-designing activities and the identification of solutions and policy implications. SPRING will then gather, summarise and share the best available research and evidence on the effectiveness, innovation, transferability, sustainability and evaluation methods for integration policies and practice. This evidence will summarise the findings of EU projects funded under Horizon 2020, AMIF, European Social Fund and Erasmus+ as well as relevant public and private donors. Summarising this evidence, SPRING will collect, create and disseminate the most usable and practical materials, such as examples of good practice, handbooks, pieces of training, templates, databases and contact lists. The SPRING online portal and repository, combined with the consortium’s communications task force and social media strategies, will make this evidence more accessible by curating the content and form to match the specific profile and needs of these communities of practice.

Keywords: sustainable integration practices,policy implications,participatory approach
STATISTICAL ANALYSIS AND AI ON PUBLIC CANCER DATA FOR THE DEVELOPMENT OF A HEALTH MONITORING SERVICE (U-MON)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Netherlands
Call: European SME innovation Associate - pilot (H2020-INNOSUP-2020-02, 2020)
Start date: 2020-12-01
End date: 2022-01-31
Duration (months): 14.0
Total project cost (EUR): 141964.29
EU funding (EUR): 99375.0
Participants: 1
Project status: CLOSED

Y2Y is a start-up company in molecular diagnostics. Y2Y develops methodology for early disease detection in body fluids and is building a biobank of longitudinal samples containing disease onset for this purpose. Y2Y aims to extend its value proposition from single disease diagnostics for the health care provider market, to general health monitoring for the consumer market. This is a disruptive transition from traditional reactive healthcare to new-preventive healthcare. To establish the potential of its technology for general health monitoring, Y2Y has phrased 2 objectives and needs a bio-informatician to perform the research to achieve these objectives. The first goal will be to elucidate - by statistical analyses of public cancer tissue data - panels of small RNA molecules whose expression levels are associated with specific types of cancer. The second goal is to use these panels for the AI-driven development of a deconvolution algorithm to predict the presence of specific types of cancer in complex expression data. The performance of such an algorithm will indicate the potential of small RNA profiling for health monitoring and allow Y2Y to chose (or chose not) to invest in development of a health monitoring product. Y2Y offers a tailored integration and education program to the associate that will result in skillsets in personalized medicine and biomarker development that will render the associate attractive to companies as well as academic groups in this field.

Keywords: statistics,biomarkers,small rna,cancer,health monitoring
Chronologicon Hibernicum – A Probabilistic Chronological Framework for Dating Early Irish Language Developments and Literature (ChronHib)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Ireland
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-09-01
End date: 2021-04-30
Duration (months): 68.0
Total project cost (EUR): 1804229.61
EU funding (EUR): 1804229.61
Participants: 1
Project status: CLOSED

Early Medieval Irish literature (7th–10th centuries) is vast in extent and rich in genres, but owing to its mostly anonymous transmission, for most texts the precise time and circumstances of composition are unknown. Unless where texts contain historical references, the only clues for a rough chronological positioning of the texts are to be found in their linguistic peculiarities. Phonology, morphology, syntax and the lexicon of the Irish language changed considerably from Early Old Irish (7th c.) into Middle Irish (c. 10th–12th centuries). However, only the relative sequence of changes is well understood; for most sound changes very few narrow dates have been proposed so far. It is the aim of Chronologicon Hibernicum to find a common solution for both problems: through the linguistic profiling of externally dated texts (esp. annalistic writing and sources with a clear historical anchorage) and through serialising the emerging linguistic and chronological data, progress will be made in assigning dates to the linguistic changes. Groundbreakingly, this will be done by using statistical methods for the seriation of the data, and for estimating dates using Bayesian inference. The resultant information will then be used to find new dates for hitherto undated texts. On this basis, a much tighter chronological framework for the developments of the Early Medieval Irish language will be created. In a further step it will be possible to arrive at a better chronological description of medieval Irish literature as a whole, which will have repercussions on the study of the history and cultural and intellectual environment of medieval Ireland and on its connections with the wider world. The data collected and analysed in this project will form the database Chronologicon Hibernicum which will serve as the authoritative guideline and reference point for the linguistic dating of Irish texts. In the future, the methodology will be transferable to other languages.

Keywords: early irish language,early irish literature,linguistic dating,absolute and relative chronology of language changes,bayesian statistical probabilities in dating
Thermal and Electrical Transport in Correlated Quantum Materials (TRANSPORT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: France
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 1438750.0
EU funding (EUR): 1438750.0
Participants: 1
Project status: SIGNED

The last decade has witnessed a revolution in the prediction and understanding of new phases of matter characterized by topology and entanglement. This includes topological insulators, semimetals, superconductors, quantum spin liquids, topological Kondo systems, etc.. However, most of the theory is directed at the classification of ground state properties and elementary excitations, and most successful experiments are spectroscopic. The big frontier is transport. The latter is the key for nearly all applications in condensed matter. It is also the most sensitive probe, and gives access to the lowest frequencies and energies. Yet its understanding remains much more primitive than that of many techniques, at a time when the body of transport experiments is rapidly growing. Responding to the need to tackle this problem extensively, the proposed ERC will provide a broad and detailed understanding of heat and electrical transport in a wide variety of quantum systems in various regimes: quantum magnets at low/high temperatures, near critical points, and semimetals. It will provide key tools and guidelines to study and understand transport in experiments. I propose to focus on two goals that I deem most direly needed for the understanding of transport: 1. Develop the theory of thermal conductivity in complex magnets, both in quantum spin liquids and more generally at high temperatures and quantum critical points, 2. Investigate transport in novel conducting and superconducting states with controllable topology induced by spontaneous symmetry breaking phenomena. Achieving these goals will enable informed interpretation of a growing body of modern experiments on correlated states. The proposed work will add to fundamental theory, develop new tools and methodologies, and forge ties to specific experiments, laying the groundwork for future applications. It will train students and postdocs in cutting-edge theory and the art of applying it to quantum materials.

Keywords: quantum materials,thermal conductivity,critical transport,frustrated quantum magnetism,quantum spin liquids,itinerant magnets,interactions in topological semimetals,spin lattice coupling,magnetoresistance
Scattering Media as a Resource Towards Information Processing and Sensing (SMARTIES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: France
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-04-01
End date: 2022-09-30
Duration (months): 66.0
Total project cost (EUR): 1999891.0
EU funding (EUR): 1999891.0
Participants: 2
Project status: CLOSED

Scattering of light in complex environments has long been considered a nuisance and an inescapable limitation to imaging and sensing alike, ranging from astronomical observation, biomedical imaging, spectroscopy, etc. In the last decade, wavefront shaping techniques have revolutionized this view, by allowing light focusing and imaging even deep in the multiple scattering regime. This principle is embodied in the possibility—that I pioneered—to access the transmission matrix of a complex medium. In SMARTIES, I will go one major conceptual step further, by exploiting directly the inherent property of a complex medium to mix perfectly and deterministically the information carried by the light. This mixing is actually a processing step. Along this general idea, SMARTIES will explore two synergistic directions: —Classical and quantum optical computing: Thanks to the highly multimode nature and the strong mixing properties of complex material, I will aim at demonstrating high performance classical computing tasks in the context of randomized algorithms. As a platform for quantum information processing, this will be relevant for high dimension quantum computing algorithms, and quantum machine learning. —Generalized imaging and sensing: Rather than tediously focusing and imaging through a scattering material, computational approaches can significantly improve and simplify the imaging process. I also aim to show that the relevant information can be directly and optimally extracted from the scattered light without imaging, using machine-learning algorithms. From a methodological standpoint, SMARTIES will require bridging knowledge from mesoscopic physics, light-matter interaction, linear and non-linear optics, with algorithms and signal processing concepts. It will deliver a whole new class of optical methods and devices, based on disorder. Its applications range from big data analysis, quantum technologies, to sensors and deep imaging for biology and neuroscience.

Keywords: complex media,wavefront control,optical computing,optical imaging,quantum computing