Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Modelling Assisted Solid State Materials Development and Additive Manufacturing (MA.D.AM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-06-01
End date: 2026-05-31
Duration (months): 60.0
Total project cost (EUR): 1999587.0
EU funding (EUR): 1999587.0
Participants: 1
Project status: SIGNED

The MA.D.AM project addresses the strong need of wire-based additive manufacturing (AM) for customized value-added metallic materials that are not established yet. The project aims at establishing novel scientific knowledge for the fabrication of novel wire materials and AM parts with hitherto not reached properties, based on the application of high-strength Al-Cu-Li alloys, as cutting-edge candidates for AM in aerospace applications. For this purpose, innovative solid-state materials development and AM processes are utilized to obtain alloys beyond the known thermodynamic borders. The solid-state Friction Extrusion process allows generating phases under non-equilibrium conditions, leading to so far unexplored microstructural states, enabling to produce novel high-performance wire material with tailored properties. To avoid microstructural deterioration and preserve or even improve the beneficial properties of the designed wires, the Solid State Layer Deposition process is employed. The overarching objective of MA.D.AM is to establish the real-world process chain paired with numerical approaches, leading to a digital twin to achieve a hitherto unavailable decryption of the composition-process-microstructure-property relationships for solid-state materials development and AM. To achieve this objective, a systematic multidisciplinary approach based on the combination of sophisticated physical modelling concepts, advanced experimental approaches including characterization techniques and machine learning is pursued. The selected modelling approaches along computational thermodynamics, microstructure and process modelling, together with special-designed (in situ) experiments will establish a clear link between process characteristics and evolution mechanisms such as phase formation and recrystallization kinetics. The digital twin will be built via a novel hybrid modelling strategy based on experimental and numerical data developed on the concepts of machine learning.

Keywords: solid state processes,friction extrusion process,solid state layer deposition,computational mechanics,modelling and experiment,machine learning,digital twin
MULTI-site organic-inorganic HYbrid CATalysts for MULTI-step chemical processes (MULTI2HYCAT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Spain,Germany,Italy,Italy,Belgium,France,France,United Kingdom
Call: Novel hybrid materials for heterogeneous catalysis (H2020-NMBP-2016-two-stage, 2016)
Start date: 2017-01-01
End date: 2021-06-30
Duration (months): 54.0
Total project cost (EUR): 5346957.5
EU funding (EUR): 5346957.5
Participants: 10
Project status: CLOSED

The main goal of MULTI2HYCAT is to design, obtain proof of concept (2 gr.) and upscale in a pre-pilot reactor (20-50 gr.) a new class of hierarchically-porous organic-inorganic hybrid materials, which will be used as active catalysts to carry out multi-step asymmetric catalytic processes with predominantly high conversions (up to 90%) and selectivity (in the range of 80-90%) towards the desired final products. The project promises to solve, for the first time, the low conversion and selectivity of current organosiliceous solids, while at the same time improving the flexibility and versatility and reducing costs of the obtained catalysts, making them attractive for a wide range of industrial applications. To this end, during the project, these novel catalysts will be demonstrated for specialty chemical and pharmaceutical applications, as a concrete prime-mover for subsequent replication. The MULTI2HYCAT project will contribute to the implementation of the EU policies and Directives on competitiveness and sustainability (e.g. Circular Economy Strategy and Resource Efficiency), through the validation of novel concepts in hybrid materials design for heterogeneous catalysis. This includes the preparation and validation of innovative hierarchical porous organic-inorganic materials with several active sites (organocatalysts) perfectly located in specific structural positions in their framework which will be used as single-solid reusable hybrid active catalyst to carry out multi-step catalytic processes. The new material will allow avoiding the extra-efforts associated with isolation of intermediate products, wastes and solvents elimination and purification processes thus enabling more efficient and sustainable catalytic routes from the economic, energetic as well as the environmental points of view.

Keywords: hierarchical porous hybrid materials,active sites,multi step catalytic processes,heterogeneous catalysis,recovery and re use of the catalyst,pre pilot reactor,specialty chemicals,pharma
Mixed-phase clouds and climate (MC2) – from process-level understanding to large-scale impacts (MC2)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Norway
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-03-01
End date: 2023-02-28
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

The importance of mixed-phase clouds (i.e. clouds in which liquid and ice may co-exist) for weather and climate has become increasingly evident in recent years. We now know that a majority of the precipitation reaching Earth’s surface originates from mixed-phase clouds, and the way cloud phase changes under global warming has emerged as a critically important climate feedback. Atmospheric aerosols may also have affected climate via mixed-phase clouds, but the magnitude and even sign of this effect is currently unknown. Satellite observations have recently revealed that cloud phase is misrepresented in global climate models (GCMs), suggesting systematic GCM biases in precipitation formation and cloud-climate feedbacks. Such biases give us reason to doubt GCM projections of the climate response to CO2 increases, or to changing atmospheric aerosol loadings. This proposal seeks to address the above issues, through a multi-angle and multi-tool approach: (i) By conducting field measurements of cloud phase at mid- and high latitudes, we seek to identify the small-scale structure of mixed-phase clouds. (ii) Large-eddy simulations will then be employed to identify the underlying physics responsible for the observed structures, and the field measurements will provide case studies for regional cloud-resolving modelling in order to test and revise state-of-the-art cloud microphysics parameterizations. (iii) GCMs, with revised microphysics parameterizations, will be confronted with cloud phase constraints available from space. (iv) Finally, the same GCMs will be used to re-evaluate the climate impact of mixed-phase clouds in terms of their contribution to climate forcings and feedbacks. Through this synergistic combination of tools for a multi-scale study of mixed-phase clouds, the proposed research has the potential to bring the field of climate science forward, from improved process-level understanding at small scales, to better climate change predictions on the global scale.

Keywords: clouds,climate,aerosols,thermodynamic phase
INNOVACTIS 2017-2018 (INNOVACTIS 2017-2018)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Spain,Spain,Spain,Spain,Spain,Spain,Spain
Call: H2020 2D CONSULTATION EEN (H2020-EEN-SGA2-2017-2018, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 247910.0
EU funding (EUR): 247910.0
Participants: 10
Project status: CLOSED

The objective of this project is to provide innovation support services in 2017 and 2018 to SMEs in the regions covered by the consortium members. These innovation support services will be differentiated for two groups of SMEs: a) SMEs that have been selected as beneficiaries of the SME instrument, phase 1 or phase 2. For these companies, the consortium members will offer Key Account Management (KAM) services, which are accompanying services for the SMEs to identify weaknesses in their innovation capacities and suitable external coaches throughout their participation in the SME instrument. b) SMEs that have high potential for growth and internationalisation but that need to improve their innovation management capacities. These companies will receive direct assessment services from the consortium members in order to detect barriers and develop and implement an action plan in order to enhance such capacities and overcome the detected barriers.

Keywords: sme instrument,eimc,innovation,innovation management
LIPOFABRIK: A ground-breaking biomolecular production platform for safer, more efficient and sustainable pest control and crop health management. (LIPOFABRIK)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: SME instrument
Countries involved: France
Call: Stimulating the innovation potential of SMEs for sustainable and competitive agriculture, forestry, agri-food and bio-based sectors (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-01-01
End date: 2018-04-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Plant pathogens are a major threat to feed and food production, being responsible for the loss of over 40% of the world food produce. Also, feed and food contaminated with microbes or their toxic by-products is banned from the market and lift trade barriers. Producers rely on plant protection products to fight pathogens, but since most of them have chemical origin, their use entails major risks. Along the hazard for the exposed applicators, chemical residues contaminate soil, water, plants and their products, posing a major threat for consumers and livestock. To reduce these risks, authorities are banning many chemicals from their use in plant protection, leaving the market with no effective alternatives. In response, we at LIPOFABRIK have developed and patented a suite of innovative biopesticide molecules of biological origin, lipopeptides. Our biopesticide molecules are effective and eco-friendly, with proven protective properties that spare plants from damaging agents, but also prevent the deposit of residues or contaminants. Today, we are able to produce and commercialize our lipopeptides at a small scale, but the need for lipopeptides in agriculture, seed protection or gardening reaches up to several hundreds of tonnes per year. This need is not being met today. Thus, the ultimate objective of this project is to optimise our technology and achieve the industrial capability to cover the market need. To achieve this goal, in Phase 1 we will conduct a Feasibility Study to help us gather input on the main technical, commercial and financial aspects influencing the project. Once completed, our project will bring significant benefits for agriculture, environment and society. It will supply safer, non-toxic and effective biopesticides, reducing the incidence of poisoning and related chronic diseases. In turn, it will secure LIPOFABRIK’s growth, expecting to reach €4.5 million profits, 20 new employees and a ROI of €6.9 per euro invested in 5 years after completion.

Keywords: crop health,antifungal,bioprotection,biostimulant,plant protection product,food supply,bioenhancer,plant health
Enhance innovation management capacities in Andalusian SMEs. CESEAND InnoAses 2019. (CESEAND InnoAses4)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Spain
Call: EEN H2020 SGA3 (H2020-EEN-SGA3-2018, 2018)
Start date: 2019-01-01
End date: 2019-12-31
Duration (months): 12.0
Total project cost (EUR): 106385.0
EU funding (EUR): 106382.0
Participants: 4
Project status: CLOSED

The CESEAND InnoAses4 project, based on the three main pillars of Excellent Science, Competitive Industries and Tackling Societal Challenges described into the 2014-2020 HORIZON 2020 work programme “Innovation in SMEs”, identifies the Innovation Management Capacities Improvement as a crucial milestone to create more innovative Andalusian SMES, enhance their relation with other potential European partners, reinforce their potential cooperation and increase the cross border activities becoming more and more competitive into the single market. Advance and tailored support into the SMEs Innovation Management Capacities is also needed in order to create a favourable ecosystem for their innovations growth, providing support to research, development and innovation projects, such as specific services aimed to improve their innovation skills and address the financing needs required by the implementation and execution of high-risk and high-potential innovation ideas to markets. This means, as described into the figure below, start analysing which ideas, from a pool of different ones, are able to arrive faster to the market, making more profitable the resources allocated for these projects. The two main objectives of this proposal are to ensure that key SME beneficiaries of H2020 are helped efficiently to fulfil their innovation potential and the innovation management capacity of the SME clients is increased; which contributes to the smart growth of Andalusia, Ceuta and Melilla; through the provision of support services as well as information and advisory services such as mentoring, coaching and partner search activities for SMEs aimed to enhance the innovation management capacities, wishing to develop innovation projects with a strong European or international potential.

Keywords: enhancing innovation management capacities services to sme s in the enterprise europe,network improve innovation health check sme empower sme instrument
Purification of Water by Harvesting Solar Radiation in a Rare-Earth (RE)-ion Quantum-dot Glass Evaporator (Q.Dot-PurE-WatER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2023-10-04
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

High-quality supply of drinking water is essential for maintaining good health and environment. The quality of water-supply infrastructure symbolizes the progress and prosperity of a nation. Increasing population overburden and unpredictable climate change on earth is making drinking water resources scarce, consequently large parts of tropics and sub-tropics are affected adversely. For making pathogen/toxic chemical-free drinking water available, low-cost sustainable approach for water purification is essential, especially in the impoverished regions of the tropics and sub-tropics, where the sunlight is abundant. In order to provide solution for this crisis of drinking water shortage, my Q.dot-PurE-WatER MC project focusses on exploiting quantum (Q)-dot rare-earth(RE)-ion-doped glass from waste phosphor lamps for re-engineering solar-energy harvesting water evaporator and filtration system, called the solar-still as demo. In a demo solar-still, the Q-dot paint layer will be applied for enhancing black-body absorption for heating water to above 95oC for killing pathogens. The solar-still will also store energy by utilizing the organic lauric acid phase change mixture for using heat after sunset. The evaporated water will be filtered through photo-sensitized nano filter for destroying vapour-transported pathogens and chemicals. My goal is to demonstrate favourable impact of solar-still for the purification of dirty water of Ganges River in collaborative research training activities at the IIT-BHU in Varanasi, India and the St. James Hospital and Water@leeds in Leeds UK. This demonstration will be achieved as a result of four training packages including impact pathways, spread over 24-months, which will include six 15-days short visits to Varnasi, India.

Keywords: quantum dot,glass,solar energy,energy harvesting,water purification,rare earths
Comprehending Judaizing practices and Zionist discourses among charismatic evangelicals/Pentecostals in the Lusophone Atlantic (LUSO-ZION)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France,Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-11-01
End date: 2028-07-03
Duration (months): 36.0
Total project cost (EUR): 263358.72
EU funding (EUR): 263358.72
Participants: 2
Project status: SIGNED

Luso-Zion examines a growing religious tendency in the world, namely the appropriation by charismatic evangelicals/Pentecostals of Jewish narratives, rituals, and even Zionist anxieties. These last have gained international attention in evangelical support for the U.S. administration’s decision to establish an embassy in Jerusalem. At the same time, Brazilian Pentecostals also now demand that far-right President Bolsonaro fulfils his campaign promises to do the same. While this adoption of Jewish liturgy, rituals, and Zionist geopolitical support by charismatic evangelical Christians is becoming more and more evident all over the world, no transnational study in the literature explains this growing tendency. To date, existing scholarship examining this phenomenon overwhelmingly focuses on U.S. cases. Against this backdrop, Luso-Zion aims to elucidate how these religious forms and political leanings are taking shape within the Lusophone context with cases in Angola, Brazil and Portugal. Through an ethnographic and geopolitical transnational comparison, this research investigates this phenomenon across multiple locations to construct a socio-cultural and political narrative that explains why contemporary charismatic evangelical/Pentecostal movements are turning to Judaism and Zionist discourses. This research contributes to a greater socio-cultural understanding of this new religious tendency and indicates the potential implications of these religiously inflicted Zionist attitudes in Lusophone geopolitics. Therefore, Luso-Zion is relevant not only because it is the first study to provide a transnational comparative framework for comprehending this new religious tendency in charismatic evangelicalism/Pentecostalism but also because it informs international relations studies and policymaking on how grassroots religious movements can be impacting contemporary geopolitics in the Lusophone Atlantic.

Keywords: christian zionism,judaizing groups,faith based diplomacy,charismatic evangelicalism,pentecostalism,lusophone christianities,religion and international relations
Novel Stromal Cell Therapy for Diabetic Kidney Disease (NEPHSTROM)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Italy,Ireland,Ireland,Ireland,Belgium,Netherlands,United Kingdom,United Kingdom,United Kingdom
Call: New therapies for chronic non-communicable diseases (H2020-PHC-2014-two-stage, 2014)
Start date: 2015-05-01
End date: 2021-10-31
Duration (months): 78.0
Total project cost (EUR): 5994373.75
EU funding (EUR): 5994373.75
Participants: 13
Project status: CLOSED

Type 2 diabetes will affect >500 million adults by 2040 and its secondary complications will generate enormous socioeconomic costs - in particular, diabetic kidney disease (DKD), which is already the most common cause of chronic kidney disease. DKD is associated with greatly increased mortality and frequently progresses to end stage renal failure. Pharmacotherapy, dialysis and transplantation represent the mainstay treatments for DKD but are costly and provide only limited protection against adverse outcomes. Mesenchymal Stromal Cell (MSC) therapy is a promising approach to halting the progression of DKD toward end-stage renal failure and may also have ancillary benefits in Type 2 diabetes. In preliminary research, we have demonstrated that a single dose of MSC simultaneously improves kidney function (glomerular filtration rate and albuminuria) as well as hyperglycaemia in animals with DKD. NEPHSTROM will conduct a multi-centre, placebo-controlled clinical trial of a novel MSC therapy for stabilization of progressive DKD, leading to superior clinical outcomes and long-term socioeconomic benefit. A key enabler for this trial is a novel MSC population (CD362+MSC, trade name ORBCEL-M) which delivers higher purity and improved characterisation compared to conventional plastic-adherent MSC. The NEPHSTROM Phase 1b/2a clinical trial will investigate the safety, tolerability and preliminary efficacy of a single intravenous infusion of allogeneic ORBCEL-M versus placebo in adults with progressive DKD. NEPHSTROM investigators will also determine the bio-distribution, mechanisms of action, immunological effects and economic impacts associated with ORBCEL-M therapy for DKD. This research will critically inform the optimal design of subsequent Phase 3 trials of ORBCEL-M. Stabilising progressive DKD through NEPHSTROM’s next-generation MSC therapy will reduce the high all-cause mortality and end-stage renal failure risk in people with this chronic non-communicable disease

Keywords: diabetic kidney disease,chronic kidney disease,msc cell,phase 1b,2a clinical trial,end stage renal disease,mechanism of action,immune response,allogeneic,health economics