Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Personalised emulsions with encapsulated fish oil for targeted and controlled delivery of omega-3 fatty acids and removal of off-flavour (PERFECTO-3)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland,Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 252728.64
EU funding (EUR): 252728.64
Participants: 2
Project status: SIGNED

The overarching aim of PerfectO-3 Project is to produce stable and personalized emulsions with encapsulated omega-3 fatty acids from fish oil with desired critical quality attributes (CQAs) for the targeted delivery of fish oil and the masking of its undesirable smell and flavour. This will be achieved by cutting-edge food research facilities in Teagasc (as a host institute) and also by involving most suitable secondment- Institute of Food Science Research CIAL (Spain) for product validation. Specifically, this Project will investigate innovative processes, such as ultrasound cavitation, using various conditions, carrier components and surfactants that crucially influence the properties of the emulsions in order to control their droplet size distribution (DSD) and thus tailor their CQAs offering personalized/ customized omega-3 emulsions. The developed products will be characterized in terms of storage and oxidative stability and a study of release and targeted delivery of omega-3 fatty acids in the human body will be performed in CIAL. PerfectO-3 is a multidisciplinary project comprising food science, chemistry and nanotechnology research fields and aims at enhancing Europe’s competitiveness by introducing cutting-edge personalized products in the agri-food sector.

Keywords: ultrasonication,emulsification,critical process parameters,critical quality attributes,droplet size distribution,stability,customised foods
Exoplanets and Belts of Exocomets Around Nearby Stars (E-BEANS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Ireland
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 1499586.25
EU funding (EUR): 1499586.25
Participants: 1
Project status: SIGNED

The conditions for the origin of life on Earth-like planets are developed during the last steps of planet formation, when the planetary system is 10 to a few hundred million years old. Of crucial importance are basic feedstock ‘volatile’ molecules for prebiotic chemistry, which could be absent from terrestrial planets that may have formed dry. The goal of E-BEANS is to study Exoplanets and Belts of Exocomets Around Nearby Stars to understand their potential to affect the presence of volatiles on terrestrial planets. Exocometary belts in the cold, outer reaches of planetary systems represent the volatile ice reservoir. Outer Neptune-like exoplanets can interact with them to send exocomets inwards, enabling volatile delivery to temperate terrestrial planets. Meanwhile, terrestrial planets continue to grow through giant impacts, massive collisions that can strip off their atmospheres, affecting their composition. E-BEANS will study these processes to enable major steps forward on several fronts. It will carry out a multi-wavelength exploration of the composition of exocomets in the terrestrial planet formation epoch, enhanced by the first model of the chemical evolution of exocometary gas, and it will link the derived compositions to exocomet formation locations, through population synthesis models applied to imaging survey data. E-BEANS will also study the diversity of planet-induced structure in exocometary belts, a signature of the planet-exocomet interaction necessary to scatter exocomets inwards, and will test an ambitious long-term plan to directly detect these Neptune analogs through ground-based mm/radio astrometry with future radio observatories. Finally, the program will explore the composition and mass of impacting terrestrial planets through the gas and dust they release as post-impact debris.

Keywords: exocomets,debris disks,planet formation,exoplanets
Data-Driven Approaches in Computational Mechanics for the Aerohydroelastic Analysis of Offshore Wind Turbines (DATA-DRIVEN OFFSHORE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Norway
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-04-01
End date: 2028-03-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

A massive upscaling of offshore wind turbines is necessary to reach the goals of the European Green Deal. However, current methodologies for analysis and design are at their limits. One of the major bottlenecks is that it is so far not possible to directly integrate experimental data into aerohydroelastic simulations of offshore wind turbines. By and large, including these data into the aerohydroelastic analysis is indirectly accomplished through the offline adjustment of those parameters that define instances of existing models. Although such a practice can reasonably improve the short-time predictive capability, the underlying models remain unmodified. Thus, further physics available in the data remains inaccessible. In the numerical simulation context, this represents a main challenge to taking advantage of the experimental data in their entirety. In this context, DATA-DRIVEN OFFSHORE proposes to simultaneously integrate these highly-valuable data into aerohydroelastic simulations through data-driven computational mechanics. Such an approach is one of the most advanced computing frameworks, and relies on the reformulation of classical boundary and initial value problems in solid and fluid mechanics such that constitutive models, boundary conditions and/or applied loads are directly replaced by some form of experimental data. DATA-DRIVEN OFFSHORE will thus enable for the first-time investigation of the aerohydroelastic behavior of an offshore wind turbine relying truly on experimental data, capturing the hidden features that these contain. This will greatly improve the predictive capabilities with respect to existing models, allow the conception of less-conservative designs, and enable upscaling beyond 20 MW of rated power, increasing the efficiency while reducing the cost per unit of power produced. Thus, it will contribute to triggering a change of paradigm for future generations of offshore wind turbines.

Keywords: offshore wind turbines aerohydroelastic analysis data driven computational mechanics theoretical foundations computational procedures interaction among data,solids and fluids
Spatial Atomic Layer Deposition for Sustainable Energy Conversion and Storage (S-ALD)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 27.0
Total project cost (EUR): 2499999.99
EU funding (EUR): 2499999.99
Participants: 1
Project status: SIGNED

SparkNano designs and commercializes Spatial Atomic Layer Deposition tools (Spatial ALD or S-ALD) redefining nanofabrication on an industrial scale. In a nutshell, SparkNano’s Spatial ALD technology deposits ultra-thin (a few nanometers thick) material onto a substrate with atomic-level accuracy. Our technology is extremely versatile: it can be used with a broad range of chemical elements and on different substrates, and it can be performed at atmospheric pressure. We have identified two commercially promising verticals where our solution delivers the most value to customers: lithium-ion batteries and Green Hydrogen, which is hydrogen made from water via electrolysis with renewable sources. In these domains, our solution not only increases the performances while reducing the costs of the end product, but it addresses key supply chain challenges related to the efficient use of scarce materials (e.g., iridium) and their recycling. This a crucial feature not only for our customers, but for Europe and the whole planet too. Our company can exploit 42 patents belonging to 11 different families. We currently have a commercially mature S-ALD machine called the LabLine that was released in 2023 This machine is purpose built for R&D and pilot lines, as its specifications (in terms of substrate size, yield, etc.) are unsuitable for the mass manufacturing applications our customers require. To address mass manufacturing, we also have TRL 6 prototypes of two machines designed for mass manufacturing: the Omega, which focuses on roll-to-roll manufacturing processes, and the Vellum, which is relevant for sheet-to-sheet manufacturing processes. During the EIC project, we will advance our innovation up to TRL 8 by maturing our technology and carry out a complete set of Factory Acceptance Tests with an external customer. Our vision is to become the global supplier of choice for coating solutions in the Li-ion battery and Green Hydrogen sectors by the end of the decade.

Keywords: atomic layer deposition,green hydrogen,li ion batteries
Targeting the Imidazoline I1 receptor as a novel treatment for Atherosclerosis (ImnovAth)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-09-01
End date: 2026-02-28
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Atherosclerosis (AT) is one of the main causes of death worldwide. Current treatments (e.g. lipid-lowering therapies) are still insufficient to tackle future CV events and we urgently need new complementary treatments to improve therapeutic efficacy. ImnovAth aims to develop the new idea of targeting a metabolite/metabolite receptor axis to complete our preclinical results with an existing pharmacological agent that blocks this pathway, with the long-term goal of moving towards clinical trials and to a marketable product. In the context of our ERC-funded project, we found a microbiota-derived metabolite that affects the development of innate and adaptive immunity. We have subsequently found that this metabolite is both associated with and causal for AT and that blockade of the sensing of this metabolite prevents AT progression. We propose: 1) Validation to demonstrate that blockade of the metabolite/metabolite receptor axis is effective in AT treatment. We will study toxicity/tolerability of the existing pharmacological agent and the effect/efficacy of the blockade of this axis with the pharmacological agent alone or in combination with other current gold-standard treatments for AT in a preclinical therapeutic setting. 2) We will reinforce our IPR position and strategy proceeding towards a marketable product based on our currently filed patent application, market analysis and industry sector contacts. 3) Dissemination and communication activities. In sum, we propose an alternative therapy for AT focused on the inhibition of a novel target that can generate an independent or a complementary therapy to existing gold-standard treatments for AT, thus increasing their effectiveness.
REMODELLING OF THE INFARCTED HEART: PIEZOELECTRIC MULTIFUNCTIONAL PATCH ENABLING THE SEQUENTIAL RELEASE OF THERAPEUTIC FACTORS (REBORN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Italy,Portugal,Belgium,United Kingdom,Spain,Germany
Call: Smart and multifunctional biomaterials for health innovations (RIA) (HORIZON-CL4-2022-RESILIENCE-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 4050412.5
EU funding (EUR): 4050412.5
Participants: 13
Project status: SIGNED

Cardiac disease remains a major societal and healthcare burden that affect nearly two million European citizens every year. The REBORN project brings together a consortium of six scientific, four SME, and two large company partners who are committed to making a step-change to the development of medical devices for cardiac applications for the treatment of people who have suffered from a heart attack (myocardial infarction, MI). A MI causes fibrosis in the heart walls, which impedes cardiac function and means there is a high risk of subsequent heart failure post-MI. There are no current treatment options to address this major clinical problem. The REBORN project will use smart and multifunctional biomaterials to deliver a new medical device in the form of a cardiac patch, to be applied to the heart in order to stimulate and support local heart tissue remodelling. The piezoelectric patch will electromechanically couple with the heart and deliver anti-inflammatory, anti-fibrotic and cardiomyocyte proliferative factors on demand, with drug release triggered by ultrasonic (US) stimulation from outside the body. Development of the device will be based on new smart multifunctional materials: electrospun piezoelectric fibres combined with smart carriers designed to work in harmony with the US. To prepare the ground for exploitation, the patch will be extensively characterised in vitro and in vivo. Accelerating the development of the patch requires an effective in vitro model for experimentation, and novel 3D bioprinting techniques will be exploited to create a 3D in vitro model in the form of a tissue engineered tubular heart chamber, capable of pumping fluid using cell contractile forces. This will give a new in vitro model capable of both functional and structural testing. The REBORN project will develop, validate and prepare for the exploitation new treatment options for post-MI fibrosis and new processes for cardiac therapy development, addressing major unmet cli

Keywords: multifunctional carriers,piezoelectric patch,electrospinning,ultrasound stimulation,myocardial infarction,advanced in vitro models
Climatization of EU Policies: The Case of Maritime Transport (EU-CLIMT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 187624.32
EU funding (EUR): 187624.32
Participants: 1
Project status: SIGNED

The objective of the research project titled “Climatization of EU Policies: The Case of Maritime Transport” (EU-CLIMT) is to explore in what ways climatization influences EU governance and impacts the power of the institutional actors. To do so, the case study of maritime transport will be employed, as it is one of the main policy areas indicated in the ‘Fit for 55’ package as crucial for the decarbonization of the European continent. In more detail, the project will analyze, first, the role of the supranational actors in promoting climate policies within the EU, with a focus on maritime transport; second, the implementation of the new green maritime transport policies by key stakeholders within the EU Member States; and, third, the impact of the said new policies on the EU’s diplomatic positions at the international level and how these are perceived by third actors. The deliverables of the project will cover a broad array of outputs, such as scholarly articles, policy briefs, podcasts, seminars and public lectures, in order to ensure the maximum possible dissemination of the results. The project will be hosted at Leiden University.

Keywords: eu governance eu policymaking climate policies climatization climate diplomacy maritime transport policies
Advanced Analysis of Stainless Steel Structures with Semi-Continuous Connections (SEMICON)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 1
Project status: SIGNED

With many prominent benefits in terms of durability, mechanical performance and architectural aesthetics, stainless steel is being increasingly used in structural engineering for improved sustainability and life-cycle performance. The unique mechanical properties of stainless steel challenge the conventional structural steel design methodology, which can lead to inaccurate and uneconomic design outcomes for stainless steel structures. An optimum solution to this issue is the emerging advanced analysis technology. With integrated structural analysis and member check, advanced analysis can fully exploit the beneficial strain hardening effect of stainless steel. However, existing advanced analysis methods assume either rigid or pinned beam-to-column connections, despite the general fact that common bolted connections in Europe are practically semi-continuous connections (SCCs), i.e. with finite rotational stiffness and moment capacity. The negligence of the semi-continuous effect can compromise the accuracy of advanced analysis, and undermine its economic benefits. To deal with this challenge, SEMICON will integrate the research strengths of the fellow and the host research group to develop an efficient advanced analysis framework for stainless steel structures with SCCs. Experimental and numerical studies will be carried out to provide the required knowledge and data for developing a component-based model to predict the full-range moment-rotation behaviour of stainless steel SCCs. This model will be integrated into an advanced analysis framework to allow more accurate, consistent and economic design of stainless steel structures. The project will complement the fellow’s research skill set and improve his transferrable skills towards further academic and professional maturity. In the long-term, the project will contribute to reducing the resource consumption and carbon emission of the construction industry, which aligns with the UN Sustainable Development Goals.

Keywords: advanced structural analysis design by analysis stainless steel structures semi continuous connections structural testing finite element analysis
Rotating black holes in effective theories of gravity (RoBHin-ETG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Nowadays, Einstein’s general relativity (GR) is the most accurate theory for the gravitational interaction. Nevertheless, GR is not compatible with quantum mechanics and is expected to be the low-energy description of a more fundamental theory, whose corrections could potentially be detected around those space-time regions where gravity is strongest: black holes. The difficulty for finding or fully controlling potential candidates for such a theory has triggered an effective-field-theory approach to gravity, by which GR gets supplemented by additional new terms to be fixed by experiment. In this regard, non-rotating black holes in effective theories of gravity are quite well understood in the literature, including relevant works by the researcher of this proposal. However, this is no longer true for rotating configurations, for which only a few solutions are known in very special theories beyond GR. Since black holes in Nature are observed to be rotating, it is crucial to generalise such results for rotating solutions. This is precisely the research objective of the project: pioneering the study of rotating black holes in the most general effective theory of gravity. It is the perfect moment for this endeavour, as GR will be tested with far more precision than ever in the coming years. The project will be carried out at the University of Cambridge and supervised by Harvey Reall, author of various seminal works on effective theories of gravity and black holes. Their worldwide reputation will be key for a high impact on the relevant scientific community. Also, the project will have an extremely positive impact on the researcher. The prestige and influence of scientists at the host department, the plethora of opportunities for quality training and the myriads of tools for an efficient two-way transfer of knowledge will provide the researcher with a highly competitive profile for future leading academic positions.

Keywords: black holes effective field theories of gravity higher curvature terms quantum corrections to einstein s gravity