Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Inclusive open schooling through engaging and future-oriented science (CONNECT)

Framework: Horizon 2020 — Science with and for Society
Programme: Encourage citizens to engage in science through formal and informal science education, and promote the diffusion of science-based activities, namely in science centres and through other appropriate channels
Action type: Coordination and support actions
Countries involved: Spain,Romania,Greece,Greece,United Kingdom,Brazil,United Kingdom,Denmark,Portugal
Call: Open schooling and collaboration on science education (H2020-SwafS-2019-2-two-stage, 2019)
Start date: 2020-09-01
End date: 2023-12-31
Duration (months): 40.0
Total project cost (EUR): 1513365.38
EU funding (EUR): 1493365.38
Participants: 10
Project status: SIGNED

Science education needs to make students more scientifically literate and encourage larger numbers to take up science careers. Open schooling approaches can make science more authentic but tend to be adopted only as extra-curricular activities, in a minority of schools or are limited to gifted and talented students. CONNECT is an inclusive, sustainable model for enabling more secondary schools to adopt open schooling by embedding science-action projects in the core curriculum, using participatory science approaches with universities and enterprises. A science-action makes science more relevant to studentsOur age is profoundly shaped by science and technology innovations. Societies must become more scientifically literate to be able to make evidence-based decisions and sustain themselves in our highly competitive world. One solution that has been proposed for increasing students' aspirations in science is to open up school through partnerships and family involvement.To make open schooling inclusive and widespread in science education, we believe 3 questions need to be addressed: Q1. How can open schooling increase the value and priority of partnership activities and reduce the barriers to entry so more schools are willing and able to adopt them ? Q2. How can open schooling facilitate the interaction between all partners (science professionals, teachers, students and their families) to result in effective learning experiences linked to R&I? Q3. How can open schooling make science careers more inclusive by giving disadvantaged students more experience and insight into professional STEM jobs, supported by professionals and their families? CONNECT is an inclusive, sustainable model for enabling more secondary schools to adopt open schooling by embedding science-action gamification projects in the core curriculum, using fun approaches of participatory science with families, universities and enterprises to increase students’ interest and confidence with science in life.

Keywords: inclusive open schooling,future oriented science,science capital,engaging science learning,open science,students teacher enterprise family partnerships,science is for me,stem ecosystem
Inverse Modeling of PArameterized physics STochastic uncertainty using process-level Observations (IMPASTO)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Other Widening
Action type: Marie Skłodowska-Curie actions
Countries involved: Serbia
Call: Widening Fellowships (H2020-WF-02-2019, 2019)
Start date: 2020-05-01
End date: 2022-04-30
Duration (months): 24.0
Total project cost (EUR): 140021.76
EU funding (EUR): 140021.76
Participants: 1
Project status: CLOSED

The emerging climate services in Europe and globally under the WMO GFCS critically depend on the science and application of Earth System (ES) modeling and prediction. An important aspect of the modelling and prediction challenge for the services is characterization of prediction uncertainty. Quantitative information about inherent uncertainty in the prediction is vital for risk assessments and decision support across public service and industry sectors. Over the past decades significant investments were made through the EC FPs into establishing the ES ensemble modeling and prediction capabilities that incorporate representation of sources of intrinsic uncertainty in the modeling systems and provide quantification of their impacts on seasonal to decadal climate prediction. The identified stakeholder priorities for the H2020 and beyond are in advancing of these prediction capabilities at regional level with high resolution models. This project is intended to contribute to the science of high resolution regional seasonal climate ensemble modeling, addressing the need for understanding and quantification of the prediction uncertainty at sub-regional and local scales. The research will focus on characterization of stochastic uncertainty associated with physical parameterizations in the regional ES models. The project will integrate the established ensemble modeling methodology from the foundational work with the global systems with a new approach to representing the stochastic uncertainty of physical parameterizations by means of inverse stochastic modeling using process-level observations. A long standing tradition in expert regional climate modeling at the hosting institution will be joined with the Researcher’s expertise and experience in geophysical modeling and cross-disciplinary methodology of data assimilation. The Researcher will be trained in the regional climate modeling and will apply the expertise to build a new research capacity at the hosting institution.

Keywords: ensemble prediction,weather and climate modeling,stochastic physics parameterizations,inverse modeling,estimation,data assimilation
International Cooperation in Aviation Research (ICARe)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Coordination and support actions
Countries involved: Germany,Spain,Belgium,Belgium,France,France,France,France,Czechia,United Kingdom,United Kingdom
Call: Identification of gaps, barriers and needs in the aviation research (H2020-MG-2017-SingleStage-RTD-MOVE, 2017)
Start date: 2017-10-01
End date: 2020-05-31
Duration (months): 32.0
Total project cost (EUR): 1792357.39
EU funding (EUR): 1790715.5
Participants: 13
Project status: CLOSED

ICARe is a Coordination and Support Action addressing the international cooperation area of the topic MG-1.5-2016-2017: Identification of gaps, barriers and needs in the aviation research. Europe has a leading position in aviation, but needs to maintain and strengthen this position. A new Strategic Research and Innovation Agenda (SRIA) was elaborated by ACARE to address this challenge. The international cooperation contributes to the achievement of SRIA goals but requires a dedicated strategy based on a holistic approach and in depth analysis. ICARe will fulfill this gap and deliver recommendations with regards to International Cooperation for the Aviation Research and Innovation. To do so, ICARe starts with the analysis of past and current cooperation in order to draw lessons. A worldwide mapping of technologies of interest for aviation – even if they originate from other sectors - will be embedded in a secured on-line database. For each of the 21 countries addressed previously by the ACARE INCO group in 2015, a detailed and documented country profile will be established, including technical and non-technical aspects (IPR, trade regulations, cultural barriers and funding organizations, etc.). These results will be enhanced by concrete dialogues and actions through 6 open platforms with the representatives of selected countries (USA, Japan, Canada, China, Russia and the 6th country to be selected during the project). Thanks to this approach, ICARe will support the European Commission in the definition on its International cooperation strategy. ICARe will also facilitate existing and future partnerships in order to fulfill the technological needs identified in the SRIA.The consortium includes 12 partners representing industries, operators, research centers, universities, and international organizations, all being members of ACARE’s working group. Important European stakeholders will be involved in the Advisory Board. Required EU contribution is less than 1,8M€.

Keywords: international cooperation,aviation,research and innovation,strategical recommandations,open platforms
Activity-dependent modulation of synapse identity (SynID)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: France
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-10-01
End date: 2023-03-31
Duration (months): 66.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

The mature brain results from the formation of precise networks between functionally and morphologically distinct types of neurons. A given neuron forms synapses with a limited number of partners and on precise subcellular localizations. Understanding what controls this specificity is mandatory not only to understand brain functions but also the aetiology of synaptopathies such as autism spectrum disorders or schizophrenia. Various molecules define the identity of each type of synapse. Furthermore, neuronal activity-dependent mechanisms sculpt and stabilize neuronal connectivity. I posit that neuronal activity controls the molecular identity of synapses and that this regulation occurs through mechanisms specific for each neuronal population, thereby regulating synapse specificity. I focus on the olivocerebellar network, which is involved in motor control and also in cognitive processes. In this well-characterized circuit, two different excitatory inputs, the climbing fibres and the parallel fibres converge on the same target, the cerebellar Purkinje cells, compete for their non-overlapping territory and possess distinct functional, morphological and molecular characteristics. Purkinje cells thus provide an ideal model to study the molecular basis of synapse identity and its regulation. In the past years, I have developed new genetic tools to dissect the molecular characteristics of the olivocerebellar network at the neuron- and synapse–specific levels. I propose to generate new mouse models to control neuronal activity, in vivo and during development, specifically in the two Purkinje cell excitatory afferents. Combining these tools, my objectives are to describe the molecular diversity of synapses, show its control by neuronal activity, and characterize the molecular determinants of synapse identity. This study will bring a unifying view of the mechanisms controlling the development of a functional brain.

Keywords: synapse,transgenesis,mouse,cerebellum
Protecting Human Rights and Public Health in Global Pandemics: A Map of the Standards Applied by EU and US Courts (THEMIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-09-01
End date: 2021-01-01
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

THEMIS asks: How do judges resolve the conflict between individual human rights and public health caused by global pandemics such as Zika, Ebola and SARS? Building on the researcher’s expertise in both EU law and risk regulation, and the supervisor’s pioneering ‘risk within rights’ framework, it focuses on EU and US case-law to create the first comparative map of judicial standards in this challenging field. It develops the role of law in pandemic preparedness; a crucial issue affecting all of us, and meets the aims of the 3rd EU Health Programme. In so doing, THEMIS recognises that lawyers do not act alone, and that the scholarly and the practical have a reciprocal impact. Thus it utilizes a ‘Lawyers meet Doctors’ dissemination strategy, facilitating inter-disciplinary impact on academic and policy experts. It features two inter-sectoral secondments enabling access to both key EU and global policy-makers (WHO; the Public Health Agency in NI), and cross-disciplinary knowledge-transfer and networking via international workshops co-run with the host institution’s Centre of Excellence for Public Health (one of five in the UK). The researcher’s home at Queen’s will be the Health & Human Rights Unit, the first such unit within a top 20 UK law school. Queen’s also enjoys ‘HR Excellence in Research Status’ and boasts a Gender Initiative for women staff and a long-established Human Rights Centre. Each of these supports the skills and training plan, as do the project’s varied outputs: including a monograph (essential for the researcher’s independent academic position), journal articles, and presentations to both the lay public and policy experts during the secondments. In line with IF objectives, THEMIS enables the researcher to use international mobility, new networks and training to attain a position of leadership in the scholarly community, and contributes to the need for a better understanding of how to prepare for, and respond to, the risks of global pandemics.

Keywords: human rights law,public health law,eu law,risk regulation,eu court of justice,echr case law,comparative jurisprudence,us case law,civil liberties,global pandemics,global health governance
Functional Agricultural Biodiversity : Optimising ecosystem service provision via functional agricultural biodiversity (FAB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2022-09-20
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

Regulating services (pest regulation and pollination) are considered to be the major ecosystem services (ES) delivered by biodiversity to agriculture worldwide. Unfortunately the expansion of modern, chemical-intensive agriculture has caused widespread declines in the abundance and diversity of beneficial arthropods (e.g. bees, natural enemies of pests) and the valuable ES they provide. Increasing plant biodiversity to enhance pollinators and natural enemies in agro-ecosystems is a promising management technique to foster ES delivery. However, the translation of increased species diversity and abundance into enhanced ES provision and thus crop yield cannot be depended upon. Furthermore, ES are currently studied in isolation and potential antagonisms between ES poorly understood. With recent research suggesting that management methods for one ES may be detrimental to the other, it is imperative that these ES are no longer studied in isolation to better understand potential antagonisms / synergies. The FAB (Functional Agricultural Biodiversity) Project will, for the first time, study the effects of plant biodiversity on the delivery of these two vital ES collectively. Performed in collaboration with ECOBIO and the company Yves Rocher, the project will utilise cereal and flower fields in NW France to investigate the spatial and temporal distribution patterns of key ES-provider species and how this translates into increased ES provision (pollination and pest regulation for the farmer). Ultimately, the research aims to find solutions for the removal of barriers that prevent or limit the delivery of pest regulation and pollination by FAB and ES management strategies and enhance yield for the farmers. A 6 months secondment to Yves Rocher will offer me unique insight into industry, learning the constraints of production and necessity to develop a marketing image, further strengthening my reputation within my field and developing future collaborative relationships.

Keywords: optimisation of ecosystem services,agriculture,pollination,pest control,crop yield,landscape management,integrated pest management,functional diversity,conservation biological control
COMMANDEER: Disrupting microbial resistance using rationally designed signalling molecules (COMMANDEER)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Ireland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-07-01
End date: 2017-06-30
Duration (months): 24.0
Total project cost (EUR): 187866.0
EU funding (EUR): 187866.0
Participants: 1
Project status: CLOSED

Cystic Fibrosis (CF) is an inherited disease which affects 100,000 people worldwide and is prevalent in European populations. CF causes the body to produce an abnormally sticky mucus in the lungs making patients susceptible to serious bacterial infection. By age 8, 50% of CF patients are infected with Pseudomonas aeruginosa increasing to 80% by 20 years of age. Eventually, the infecting strains of bacteria become resistant to antibiotics and remain a chronic inhabitant of the lungs of CF patients until they succumb to respiratory failure, usually by the young age of 30-35. Approximately 60% of CF patients are co-infected with Burkholderia cenocepacia that settle into the thick mucus of the airways. These bacteria have evolved a special type of defence mechanism to antibiotics whereby they excrete a chemical messenger on treatment. This chemical messenger -Diffusible Signal Factor or DSF - activates bacterial biofilm formation. Previous work has shown that DSF effectively behaves as an ‘emergency flare’ to other bacteria, which produce a biofilm in response. This biofilm acts as a shield which protects the bacteria from the effects of antibiotics. As a key fits in a lock, DSF fits into bacterial receptors and “switches on” biofilm formation. In this COMMANDEER project, we will synthesise molecules which mimic DSF and fit into the same biological receptors. However, due to subtle changes in their design, our molecules will “switch off” biofilm formation. Using this novel strategy of effectively commandeering the bacteria’s signalling system, we will disable biofilm formation, making the bacteria susceptible to antibiotics once again. We will adopt a multidisciplinary and collaborative approach combining the talents of chemists in Ireland and microbiologists in the UK. This project, therefore, represents a new and exciting route of circumventing bacterial resistance, offering significantly improved quality of life for CF patients and increased life expectancies.

Keywords: medicinal chemistry,bioisosteres,cystic fibrosis,bacteria,resistance,quorum sensing
Literature against anti-Semitism (1940-1944). French and Soviet emigré writers in France against the persecution of the Jews (LIAGAN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-01
End date: 2017-05-31
Duration (months): 24.0
Total project cost (EUR): 185076.0
EU funding (EUR): 185076.0
Participants: 2
Project status: CLOSED

The research project Literature against anti-Semitisme (1940-1944). French and Soviet emigré writers in France against the persecution of the Jews aims at investigating the views which writers had of the persecution of the Jews in Occupied France. More exactly, it aims at approaching the texts of the writers who reacted to the injustices suffered by the Jews who became exiles and were hunted down as Others, before being simply eliminated. In this context, we intend to study various works of fiction (stories, novels, poetry) in which the question of the persecution of the Jews is at stake. The project is defined by two axes: (1) the French writers who raised their voices against the persecutions of which the Jews were victims in France, (2) émigré writers from Central and Oriental Europe (Russian, Russian-language, Georgian) who lived in France during the Occupation and who also stood up against these injustices. Two circumstances which are specific to France have to be taken in account. Firstly, the persecution of the Jews in France implemented by the Vichy government during the Occupation needs to be understood in the context of a national/local anti-Semitic policy the roots of which are to be found in the pre-war society. Secondly, the public role of the writers was more important compared to other countries. If many of them had raised their voices against the events unfolding in Europe, this voice is acquiring a decisive importance in the shaping of public opinion. In approaching the problem of resistance in France to the Nazi occupiers, it would be necessary to consider the flows of immigration affecting the country in the twenties and thirties, when a large number of intellectuals and writers arrived from Central and Eastern Europe and took part in French cultural and public life, among other things by sharing its opposition to the rise of Nazism in Europe.

Keywords: committed literature,occupation,antisemitism,jews,emigr literature