Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Controlled Mechanical Manipulation of Molecules (CM3)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-01-01
End date: 2023-12-31
Duration (months): 72.0
Total project cost (EUR): 1465944.0
EU funding (EUR): 1465944.0
Participants: 1
Project status: SIGNED

The idea to freely control the atomic-scale structure of matter has intrigued scientists for many decades. The low-temperature scanning probe microscope (LT SPM) has become the instrument of choice for this task since it allows the rearrangement of atoms and molecules on a surface. There is, however, no generic SPM-based method for the manipulation of molecules beyond lateral rearrangement. The goal of this project is to develop controlled mechanical manipulation of molecules (CM3) in which a LT SPM is used to handle large organic molecules in three dimensions with optimal control over position, orientation and shape. CM3 will become a game-changing technique for research on molecular properties and molecular-scale engineering, because it combines fully deterministic manipulation with broad access to molecular degrees of freedom for the first time. In CM3 the tip is attached to a single reactive atom within a molecule. Tip displacement guides the molecule into a desired conformation while the surface provides a second (weaker) fixation. The fundamental challenge addressed by this project is the identification of precise molecular conformations at any time during manipulation. The solution is a big data approach where large batches of automatically recorded SPM manipulation data are structured using machine learning and interpreted by comparison to atomistic simulations. The key idea is a comparison of entire conformation spaces at once, which is robust, even if the theory is not fully quantitative. The obtained map of the conformation space is used to determine molecular conformations during manipulation by methods of control theory. The effectiveness of this approach will be demonstrated in experiments that unambiguously reveal the structure-conductance relation for a series of molecules and that realize the engineering paradigm of piecewise assembly on the molecular scale by constructing a direct current rotor / motor from individual components.

Keywords: scanning probe microscopy
Piezoelectric Energy Harvesters for Self-Powered Automotive Sensors: from Advanced Lead-Free Materials to Smart Systems (ENHANCE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Germany,Italy,Italy,France,France,France,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2016, 2016)
Start date: 2017-05-01
End date: 2021-10-31
Duration (months): 54.0
Total project cost (EUR): 3382787.16
EU funding (EUR): 3382787.16
Participants: 9
Project status: CLOSED

The proposed Initial Training Network entitled "Piezoelectric Energy Harvesters for Self-Powered Automotive Sensors: from Advanced Lead-Free Materials to Smart Systems (ENHANCE)" will provide Early Stage Researchers (ESRs) with broad and intensive training within a multidisciplinary research and teaching environment. Key training topics will include development of energy harvesters compatible with MEMS technology and able to power wireless sensor. Applied to automobiles, such technology will allow for 50 kg of weight saving, connection simplification, space reduction, and reduced maintenance costs - all major steps towards creating green vehicles. Other important topics include technology innovation, education and intellectual asset management. ENHANCE links world-leading research groups at academic institutions to give a combined, integrated approach of synthesis/fabrication, characterization, modeling/theory linked to concepts for materials integration in devices and systems. Such a science-supported total engineering approach will lead towards efficient piezoelectric energy harvesters viable for the automotive industry. ESRs will focus on this common research objective, applying a multidisciplinary bottom-up approach, which can be summarized by : "engineered molecule- advanced material- designed device - smart system". ENHANCE also seeks to intensify the relationship between academic and private sectors, and to train highly skilled young researchers for new materials and device technologies. Both are essential to provide a strong European lead over the rest of the world in this highly competitive industry.

Keywords: hybrid vibrational piezoelectric harvesters,power electronics,mems,piezoelectrics,pyroelectrics,multiferroics,films,nanostructures,molecular engineering,mechatronics
Nano-mechanical quantum photonic circuits (NANOMEQ)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Denmark
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-01-01
End date: 2025-12-31
Duration (months): 60.0
Total project cost (EUR): 1485362.0
EU funding (EUR): 1485362.0
Participants: 1
Project status: SIGNED

Photons are essential for transmitting quantum information and for building entangled system on a global scale. Recent developments in photonic quantum technologies provide the fundamental tools for generating and manipulating photons within a chip. Yet, performing large-scale experiments, involving many quantum bits (or qubits), remains a major challenge due to the lack of a method to incorporate and control many sources of identical photons in the same chip. With an efficient strategy to control quantum photonic circuits, single-photon sources, and multi-photon entanglement, a fully-integrated platform for quantum information processing with many qubits and logical gates, can be built. In this project, I intend to merge two flourishing fields of research, opto-mechanics and deterministic photon-emitter interfaces, in order to achieve active control of quantum circuits and to realize large-scale nano-mechanical quantum photonic circuits. Unparalleled by other methods, nano-mechanical systems enable full control over light propagation in optical circuits with exceedingly low loss and noise, which makes them fully compatible with single-photon emitters. The main highlights of NANOMEQ are to: 1. Build the world’s smallest and most efficient photonic quantum gate. 2. Control light-matter interaction to efficiently extract, in a scalable fashion, many high-fidelity photonic qubits from a deterministic single-photon source. 3. Perform on-chip frequency conversion to telecom wavelengths for long-distance communication. These achievements will be milestones in quantum photonics and, by addressing outstanding challenges in the field, will pave the way for scaling-up deterministic photon-emitter interfaces for advanced quantum-information processing and beyond.

Keywords: semiconductor quantum dots,nano opto mechanics
ProbeFix: an Innovative MedTech Solution to improve the use of ultrasound for better Cardiac diagnosis in the EU (ProbeFix)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Netherlands
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-06-01
End date: 2018-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Cardiovascular Disease accounts for 45% of mortality in Europe as a whole, a number which will increase as more and more people reach old age. In sonography, which is crucial in diagnosing CVD, up to 90% of professionals are experiencing work-related musculoskeletal disorders (WRMSD, also called RSI). There is evidence that 20% of sonographers suffering from WRMSD eventually suffer a career ending injury. This is highly undesirable, especially considering the ever growing demand for cardiac health care professionals. In 2016, new industry standards for the prevention of WRMSD in sonographers have been introduced, but these have not eradicated the problem. USONO has developed the ProbeFix, a fixation device for ultrasound probes, which removes the need to manually keep the ultrasound probe in place. This solution greatly improves sonographer’s working conditions, with the added benefits of increasing reproducibility of scanned images across different operators and patients, and significantly reducing the time an echo scan takes. USONO is will introduce the ProbeFix to the EU market in the next 1-2 years, quickly realizing an impact on cardiac health care and sonographer’s working conditions. There are over 100,000 cardiologists/sonographers in the EU, working in approx.. 10,000 hospitals and cardiac centres. These treat 49 million patients a year, a number that is steadily growing, with a total of over 75 million cardiac echography scans per year. USONO has started selling the ProbeFix in Europe. The main objective of this SME Phase 1 project is to explore and assess the possibilities of scaling-up the ProbeFix in the EU and eventually the rest of the world and bring it ultimately to TRL 9 in Phase 2. Furthermore, the business case and plan needs to be updated, elaborated and further improved, in order to effectively and efficiently introduce the ProbeFix in the EU and, later on, in the world market.

Keywords: echography,ultrasound,sonography,cardio echo,wrmsd,cardiologist,diagnostics
StarLink: The World's First Intelligent Vacuum Pump System (StarLink)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-05-01
End date: 2018-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Vacuum pumps are used in thousands of industrial applications, playing a vital role in food processing, semiconductors, chemicals, pharmaceuticals and many other manufacturing and assembly processes. However, today’s pumps are currently unable to provide any type of insights that could help users anticipate a pump malfunction, plan maintenance procedures or setting the adjustments. Pump malfunctions or breakdowns, due to unplanned maintenance or improper settings, cost millions of euros in lost revenues every year as production and logistic lines lie idle waiting for pumps to be fixed, and when they are not optimized their productivity decrease or their energy consumption go up. But now, DVP, a vacuum pump manufacturer, has developed the solution to these challenges through StarLink, the world’s first intelligent vacuum pump system. StarLink is a patent-pending system that uses data analytics and machine learning to identify pump malfunctions before they happen, propose actions to be taken, and automatically adjust the operation parameters if the problem relates to the setting. This will reduce pump downtime-related costs by 30%, increase their productivity by 50% and make easier the operation manager tasks. The combination of our deep knowledge of vacuum pumps needs with the machine learning expertise of the university of Ferrara will create the most intelligent device to improve the competitiveness of European companies. Additionally, StarLink will contribute to DVP’s growth in terms of employees and product portfolio since we will be able to offer a wider range of products and services related to vacuum pumps, which will allow us to enter new markets and sell more units. By 2023, it will generate €3M in yearly revenue with net profits of €2M to our company.

Keywords: industry 4 0,artificial intelligence,vacuum pump,machine learning,data analytics,industrial data,platform as a service paas,predictive maintenance,closed loop,automated settings
ecoSystems Connected to AcceLerate and Encourage European Union start-uPs with high Potential (Scale-EU2p)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Austria,Germany,Austria,Germany,Spain,France,France
Call: Startup Europe for Growth and Innovation Radar (H2020-ICT-2017-1, 2017)
Start date: 2017-12-01
End date: 2020-10-31
Duration (months): 35.0
Total project cost (EUR): 1513612.19
EU funding (EUR): 1423228.75
Participants: 10
Project status: CLOSED

Scale-EUp2 (ecoSystems Connected to AcceLerate and Encourage European Union start-uPs Potential) is a market driven action which ambitions to identify a portfolio of a minimum 200 high potential start-ups through the 4 connected hubs and to help them scale-up and to become leaders in the emerging Internet of Things (IoT) applications markets. The 4 Ecosystems will join their efforts to scout-out for the high potential start-ups in need of resources, the hubs regional markets making it like a European spider-web. The ecosystems’ scouting will extend to the overall European IoT markets by exploiting value chain analyses and the mobilization of European market stakeholders from the hubs and beyond. The partners from the hubs will also provide support, once the different facets of scouting has been completed, to organize match-making, to help the selected start-ups to join innovation projects and thus establish partnerships, alliances allowing to reinforce the valuation of the start-ups. At the same time, the partners will develop and set up tools for the start-ups to gain access more easily to financing as well as to the human resources market. .

Keywords: scale up,high tech,internet of things iot,finance,recruitment
Stellar Populations and Dynamics: a comprehensive IMF analysis (SPanD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany,United States
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-05-01
End date: 2020-04-30
Duration (months): 36.0
Total project cost (EUR): 239860.8
EU funding (EUR): 239860.8
Participants: 2
Project status: CLOSED

The number distribution of stars by mass in a stellar system, at birth, is given by the initial mass function (IMF). The IMF not only regulates the chemical enrichment of a galaxy, but it also determines its spectrum and the mass scale. Moreover, it is the bridge between the physics and properties of individual stars and the light that we observe from distant galaxies. Therefore, the IMF constitutes a fundamental piece in modern Astrophysics. Since the pioneers works suggested an invariant IMF in all star-forming systems, the universality of the IMF has been a common assumption in every extra-galactic study over the last 50 years. However, recent claims of IMF variations in nearby massive galaxies have challenged this standard picture. The Stellar Populations and Dynamical (SPanD) project aims to perform critical study of these IMF variations, by combining both stellar populations and dynamical techniques to derive the IMF in nearby and high-redshift objects. Given the strong dependence of most of the astronomical observables on the IMF, a comprehensive IMF analysis as proposed in SPanD is crucial to better understand our observations, and ultimately, to understand how galaxies have formed and evolved.

Keywords: galaxies formation galaxies evolution galaxies stellar populations galaxies dynamics
Interfaces for Relational Listening: body, telematics, memory, migration (INTIMAL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-01
End date: 2019-08-31
Duration (months): 24.0
Total project cost (EUR): 208400.4
EU funding (EUR): 208400.4
Participants: 1
Project status: CLOSED

In the European context of migration and diasporas, and at the intersection of sound art, music cognition, psychology and human-computer interaction, this project will develop INTIMAL: a novel physical-virtual “embodied system” for relational listening. Through the artistic practice of telematic sonic performance this system will interconnect people’s bodily motion and voice with their memories and dreams of distant locations. The fellowship aims to equip the researcher with cutting-edge tools and transferable skills for creating sonic relations for both well-being and healing, tackling important societal challenges of migration. The project will use a unique practice-based methodology, combining different types of listening: relational listening (in dialog with the surroundings), deep listening (sonic meditations, dream and body awareness), networked listening (through telematic performance), and body sonification (translating motion to sound). These will inform and be informed by the development of the modular software platform INTIMAL. As a case study, nine Colombian migrant women in Europe will test INTIMAL in their listening experiences as a catalyst for healing and reconciliation within the context of Colombian post-conflict and peace building. At the University of Oslo the researcher will gain artistic, conceptual and technological skills through: (a) the exploration of artistic, psychological, scientific and cultural implications of capturing the body while listening; (b) the development of spatiotemporal models that interrelate data sources using a graphical programming environment (Max with Jamoma) in a system; (c) the development of complex and meaningful relational processes for telematic sonic performance. Throughout the two years the project will reach academic and non-academic audiences, opening career opportunities for the researcher’s unique profile for the design of interfaces for relational listening, within a variety of dislocation contexts.

Keywords: telematic performance,sound studies,listening,embodiment,migration,colombia,creative computing
The Role of Neuroinflammation in Alzheimer’s Disease (INFLAMM-ALZ)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-11-01
End date: 2019-10-31
Duration (months): 24.0
Total project cost (EUR): 173857.2
EU funding (EUR): 173857.2
Participants: 1
Project status: CLOSED

Alzheimer’s disease (AD) is a major public health problem with substantial economical and social impacts worldwide. Despite intense research, the pathological mechanisms of AD are still unclear. Under homeostasis, a delicate balance is struck between disposal of pathogenic proteins by the brain’s immune cells, microglia, and the inflammation produced by these cells. Indeed, during an acute activation, microglia are protective, but if microglia enter an over-activated state they can induce chronic inflammation through oxidative stress that in turn leads to neuronal damage. Thus, gaining data on the chain of events involved in microglial action is a prerequisite to understanding AD. This project is a large interdisciplinary collaborative effort involving well-established methods such as confocal imaging and transgenic zebrafish, with newly developed photopharmacological tools. Drs Kettunen, Grøtli and Andréasson provide the world-leading expertise required for the project. By coordinating this project, Dr Mourabit will gain invaluable experience in biomedical research, photochemistry, project management, supervision, and the production of scientific results. The novel photoresponsive probes used here will allow for photonic in vivo de/activation of microglia, generating new information on their spatiotemporal activity, in real-time. This state-of-the-art resolution of cell-tracking and control of microglial signalling will provide innovative data on the pathology of neuroinflammation. We believe this interdisciplinary team will push the boundaries of research in AD. This project has the potential to identify new treatments for AD, and influence the direction of neurobiology. This project will create a unique career opportunity for Dr Mourabit, enabling him to crossover from an environmental background to biomedical research. The marrying of such interconnected disciplines will help Dr Mourabit set the foundations of an eclectic and vibrant research group.

Keywords: alzheimer s disease,pathology,inflammation,neurodegeneration,neurobiology,animal,behaviour,microglia,photopharmacology,transgenic,zebrafish,confocal imaging,learning,memory