Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A new innovative way to upskill and reskill your deskless workers: Predictive and adaptive learning (Vignita)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Norway
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-07-01
End date: 2024-06-30
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Team Vignita believes in empowering the human potential through groundbreaking education technology. We're experiencing the biggest workplace change in history. Within the next ten years AI and automation will impact hundreds of millions of jobs. So, there will be a massive demand for upskilling and reskilling. Therefore, we have invented a B2B learning network that allows for collaboration and seamless sharing of skills amongst colleagues, clients and partners. Having every training tool at your fingertips Vignita aims to power blended, adaptive and predictive learning through one data driven, intelligent and unified process so professionals can learn more. Faster. Existing solutions are either distributed stand-alone learning management systems or platforms targeting highly-educated white collar professionals with elearning, which in reality means self-study. But, they do not serve the needs of deskless workers, because they require a combination of both theoretical and practical training. We solve this by connecting professionals with experts that deliver both theoretical and practical training via a user friendly interface designed for users of low computer literacy. Our application gathers a vast amount of internal and external data which will be the foundation for our machine learning algorithm for predictive and adaptive learning. This will allow both employers and employees to upskill and reskill in parallel with the green and technological transitions. - Predictive learning means that Vignita will understand and predict what you and your team should learn today in order to stay competitive in the future. - People are different. Adaptive learning is when Vignita learns when you get your best results, determine your unique learning profile and tailor the best training for you.

Keywords: machine learning,ai,predictive learning,adaptive learning,deskless workers,upskilling,reskilling
Reliable Vulnerable Road Users Behaviour Prediction Considering Spatiotemporal and Socialized Interactions (ReSIN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 1
Project status: SIGNED

As a connection module between the perception layer and decision-making control layer of autonomous vehicles, behaviour prediction is one of the research focuses in this field. The existing behaviour prediction technoAs a connection module between the perception layer and decision-making control layer of autonomous vehicles, behaviour prediction is one of the research focuses in this field. The existing behaviour prediction technologies have the problems of unclear spatiotemporal interaction coupling mechanism and socialized interaction mechanism between the target object and environment, which makes it difficult to achieve accurate behaviour prediction and seriously restricts the practical application of this technology in the field of autonomous vehicles. Aiming at complex high-load mixed traffic flow scenarios, this project takes Vulnerable Road Users (VRUs, e.g. pedestrians, cyclists, etc.) as the research objects, and conducts research on the theories and key technologies of behaviour prediction driven by spatiotemporal and socialized interactions. The content includes: VRUs-vehicle coupling mechanism investigation in spatiotemporal domain and spatiotemporal interaction modelling; VRUs-vehicle socialized mechanism study in social psychology aspect and adaptive socialized interaction modelling; synergistic driven mechanism study in multi-model integration field and dynamic ensemble learning modelling; and validation and optimization of VRUs behaviour prediction models. The vision of ReSIN is to develop an accurate, interpretable and robust/resilient VRUs behaviour prediction model for AVs to behave safely, efficiently and confidently under complex and uncertain traffic environments. By empowering AVs with this prediction capability, ReSIN will enable a seamless integration into the decision-making and planning modules of AVs, which will allow AVs to comprehend and predict the intricate patterns and variability in VRU behaviour in dynamic changing environments.
Mobilizing European Communities of Practice in bio-based systems for better governance and skills development networks in bioeconomy (BioGov.net)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Coordination and support actions
Countries involved: Estonia,Greece,Portugal,Slovakia,Italy,Czechia,Netherlands,Germany
Call: Improving understanding of and engagement in bio-based systems with training and skills development (HORIZON-CL6-2021-GOVERNANCE-01, 2021)
Start date: 2022-06-01
End date: 2025-05-31
Duration (months): 36.0
Total project cost (EUR): 2499167.5
EU funding (EUR): 2499167.5
Participants: 10
Project status: CLOSED

BioGov.net project engages 10 experienced partners to mobilize local resources and stakeholders in eight EU states (Estonia, Italy, Netherland, Greece, Slovakia, Czech Republic, Portugal and Germany). The project aims strategically to support the establishment of innovative governance models in bioeconomy to achieve better-informed decision-making processes, social engagement of all actors and uptake of sustainable innovations in bioeconomy. With the specific objective to provide validated guidelines for bioeconomy training and mentoring based on case studies from 8 EU regions, BioGov.net undertakes to: - identify and assess from the perspective of using the good practices and successful case studies for novel training framework, - complete an assessment based on regional capacities, opportunities, barriers and potentials; - define regional needs and expectations, local feedstock availabilities and use, governance barriers, social and economic landscape; - identify needs for skills required by the novel business models and related social measures to enable consumers, industry and public bodies to switch to socially and environmentally responsible behaviour within their spheres (e.g. regulatory measures, corporate responsibility initiatives, education and training). The methodology of the project ensures the synergies between respective parties, transparency of actions and inclusiveness of all actors, incl the socially vulnerable groups. Based on the collected materials, analyses and Quintuple Innovation Helix approach, the project develops guidelines for the setup of the modern and inclusive training and mentoring frameworks and programmes in specific European regions targeting the local bio-systems, regulators and policies for building the bridge between knowledge, skills, bioeconomy and good governance.

Keywords: quintuple helix,mobilizing local resources,training guidelines,novel governance models,bioeconomy skills
On Southeast Asian Terms. Tracing the Ideas of Local Sultans in the Paper Archives of Colonial Empires. (OnSeaT.TraILSPACE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 1
Project status: CLOSED

This project in global diplomatic and colonial history aims to explain how Southeast Asian Sultans’ ideas and perspectives influenced colonial relations in c. 1750-1920. The project’s comparative method focuses on three courts in maritime Southeast Asia (Sulu, Johor, and Mataram) that offer compelling parallels and divergences in their interaction with European colonial powers. The project analyses specific key terms and phrases in manuscripts written and collected at the courts, that reflect on crucial aspects of rulers’ political priorities, ideas and motivations. Building on the applicant’s prior research experience, the research innovatively then uses recent advancements in archival digitization and automatic handwritten text recognition technology, which is applied to trace variations and translations of the key terms and phrases in colonial archival records, primarily the rulers’ correspondence and treaties with colonial powers. By automatically identifying and comparing how Southeast Asian terminology reverberated in the archives and knowledge production of the British, Dutch and Spanish colonial empires in Southeast Asia, the project uncovers the potential influences of local ideas on processes and practices of diplomatic interaction, treaty-making and, thus, on the vocabulary and legal frameworks of European colonial empires. In doing so, the project challenges established paradigms that prioritize European colonial frameworks as the sources of political organization in colonial and postcolonial Southeast Asia. It contributes to growing strands of global history that reveal the influence of non-European actors, practices and knowledge within global frameworks. This encourages more polyvocal and less Eurocentric perspectives in public debate and history writing to clarify the long-term consequences of colonialism and its impact on international relations and current socio-political fabrics, identities and conflicts in and beyond Southeast Asia.

Keywords: southeast asia,international history,global interaction,empire,digital humanities,manuscripts
Advanced Agrochemical Delivery via Hybrid Nanoparticle-Cocrystal Systems (AgroNanCo) (AgroNanCo)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-02-01
End date: 2028-01-31
Duration (months): 24.0
Total project cost (EUR): 209483.28
EU funding (EUR): 209483.28
Participants: 1
Project status: SIGNED

The controlled use of agrochemicals, such as fertilizers and pesticides, is a major priority in the new Horizon Europe programme due to their environmental impact on water and soil pollution. Substrates with high loading capacity and controlled release ability have been proposed as agrochemical delivery systems. However, a significant issue with these strategies is the low aqueous solubility of some active agents, which limits their loading capacity. Among other technologies, crystal engineering has emerged as a powerful tool to modify the properties of active molecules through cocrystallization strategies, which is a feasible approach to improve the solubility of agrochemicals and increase their loading capacity in the substrate. The main objective of the Advanced Agrochemical Delivery via Hybrid Nanoparticle-Cocrystal Systems (AgroNanCo) project is to develop innovative and low-cost multicomponent materials with high loading capacity that enable the controlled release of agrochemicals with low aqueous solubility. Dr Acebedo proposes a novel strategy to combine the use of agrochemical cocrystals with inorganic substrates, mainly of Hydroxyapatite and Calcium Carbonate nanoparticles (NPs), thus creating hybrid multicomponent materials that exploit the advantages of both. This approach aims to enhance the solubility of agrochemicals via cocrystallization, allowing for higher concentrations in solution and greater loading capacities, while the NPs will act as a delivery system, allowing for local action and controlling the release of the agent, helping to mitigate environmental contamination. Additionally, Dr Acebedo will derive NPs from biomass waste materials produced in the fishing industry, such as fish bones and mollusc shells, providing a sustainable solution for waste management and supporting the principles of the circular economy by effectively repurposing fishing industry waste and reducing the environmental impact.

Keywords: agrochemical nanoparticle cocrystal circular economy
Revealing plasticity of developmental cell fate decisions by single-cell RNA labelling (sc-LAB2FATE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: SIGNED

Every time an egg is fertilised, the cellular diversity of an animal must be rebuilt from scratch. Therefore, a central question in developmental biology is how cells differentiate to acquire distinct fates. A combination of genetics, molecular biology, and microscopy approaches has led to fundamental discoveries. Recently, single-cell genomics has enabled the analysis of transcriptional differentiation trajectories at unprecedented scale and resolution. However, ordering single cells by transcriptome similarity only gives ensemble averages of differentiation trajectories and not the full spectrum of cell state transitions. It then remains unclear whether cells can commit to their fate at different stages of development or change differentiation trajectories. The sc-LAB2FATE project proposes to measure how single-cell transcriptomes change over time in living zebrafish embryos using a new RNA labelling methodology. This will reveal the full spectrum of differentiation trajectories during gastrulation, allowing to see not only the major routes of differentiation, but also rare alternative trajectories. Single-cell RNA labelling, biochemical nucleoside conversion and sequencing will be used to measure mRNA kinetics and transcriptome dynamics of zebrafish embryos at single-cell resolution. Spontaneous cell fate changes during normal development will be contrasted with induced cell fate changes upon cell transplantation from different cell types to decipher signalling interactions. This project will leverage single-cell genomics and traditional approaches in developmental biology to build a conceptual framework for analysing embryonic development as both a genetically programmed and a self-organised phenomenon, and to provide a general blueprint of how one can study perturbation response using metabolic labelling in living systems.

Keywords: zebrafish development,cell fate decisions,single cell rna seq,rna labeling,cell cell interactions
Controlling immunity with small molecules for a better therapy (IMMUNOCON)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: Transition Open 2024 (HORIZON-EIC-2024-TRANSITION-01, 2024)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 3549572.84
EU funding (EUR): 2484700.99
Participants: 1
Project status: SIGNED

The IMMUNOCON project aims to advance EMT-224, a first-in-class small molecule immune activator, towards clinical readiness to address the urgent need for effective therapies for late-stage solid cancers, such as colorectal cancer (CRC). CRC is the third most common cancer globally, with limited treatment options for advanced stages, resulting in poor prognosis and high mortality rates. While immunotherapies, such as immune checkpoint inhibitors (ICIs) have revolutionized management of certain solid cancers, many CRC patients do not respond to treatment due to the immunologically 'cold' nature of these tumours. EMT-224 represents a potential breakthrough in immunotherapy by converting 'cold' tumours into 'hot' ones, thereby enhancing the efficacy of ICIs. This innovation builds on results from the ERC Proof of Concept project IMMUNOSTIM, where EMT-224 was identified as a potent immune activator capable of breaking cancer immune evasion mechanisms. The IMMUNOCON project will finalize the pre-clinical validation of EMT-224, focusing on its safety and efficacy in in vivo cancer models. This will involve CTA-enabling studies, GMP manufacturing preparations, and a comprehensive commercial roadmap. The project will also establish a robust business strategy for EMUNO Therapeutics GmbH (EMT), positioning it as a leading early drug discovery company in the immunotherapy field. The goal is to mature EMT to support the clinical development and eventual commercialization of EMT-224, which has strong 'pipeline-in-a-product' potential for a broad range of solid cancers. By the end of the project, EMT-224 will be poised for Phase 1 clinical trials, marking a significant step towards bringing a novel, effective treatment to patients suffering from late-stage CRC and potentially other cancers.

Keywords: nlrp3 inflammasome,small molecule immune cell activator,colorectal cancer therapy,preclinical drug development
DENIsovan anCESTORs in Sahul: deciphering human evolution through molecular techniques (DENI-CESTOR)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-30
End date: 2024-09-29
Duration (months): 24.0
Total project cost (EUR): 198296.96
EU funding (EUR): 198296.96
Participants: 1
Project status: CLOSED

Field and science-based discoveries over the last decade have revolutionised our understanding of human evolution outside of Africa. We now know that at least 6 or 7 hominin groups lived in Eurasia in the past 200,000 years. Some of these, i.e. Denisovans, Neanderthals and early modern humans, met and interbred with genes from extinct archaic hominins passing down to modern humans living today. Recent DNA studies have shown that selected populations in Southeast Asia, and Oceania in particular, have inherited genetic material from Denisovans, with the highest percentage found in Papua New Guinea (PNG) and Aboriginal Australians. Multiple divergent ancestries are seen in PNG with two unique Denisovan lineages; the latest (D1) occurring as late as ~ 30-15 k years ago. While hugely relevant for understanding hominin dispersals, admixture and adaptation, the Pleistocene and early Holocene archaeological and palaeoanthropological records of PNG are poorly understood. The rarity of hominin fossils from this region is a significant limitation in testing current hypotheses on Denisovan presence in Sahul during the Late Pleistocene. The aim of this project is to analyse two previously excavated archaeological assemblages from highland PNG (Yuku and Kiowa, with the oldest dates ~10-15 ka BP) to expand the record of hominin fossils and provide detailed information on the taxonomy and chronology of these unique assemblages. Through extensive application of Zooarchaeology by Mass Spectrometry (ZooMS) analyses of unidentified bone fragments, radiocarbon dating, stable isotope analysis, and ancient DNA analyses I will analyse new hominin fossils as well as understand early subsistence strategies and adaptation to new environments. This will be focused on the Papuan Highlands which is a hugely under-researched but increasingly significant part of the world for deciphering recent human evolution.

Keywords: human evolution,denisovan ancestry,human dispersal in sahul,zooms applications,island south east asia
Flexible and Improved Border-Crossing Experience for Passengers and Authorities (FLEXI-cross)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Border Management
Action type: Innovation actions
Countries involved: Italy,Romania,Cyprus,Greece,Germany,Moldova, Republic of
Call: Improved border checks for travel facilitation across external borders and improved experiences for both passengers and border authorities’ staff (HORIZON-CL3-2021-BM-01, 2021)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 5019000.0
EU funding (EUR): 3974400.0
Participants: 12
Project status: SIGNED

The FLEXI-cross project aims to increased security and reliability of EU border checks for people and goods, while enhancing and improving the border management capabilities, through the development, deployment and validation of a toolkit of innovative border-checking solutions, in real operational environments, addressing road, rail and port borders. The resulting flexibility and dynamicity of border check planning will offer novel capabilities such as dynamic deployment of check-points and support via mobile applications for border personnel, while guaranteeing high level of security, privacy of personal data and protection of people's fundamental rights. Through the FLEXI-cross solutions the following functionalities will be delivered: i) anti-trafficking and anti-smuggling protection via predictive risk assessment of vehicle and people, ii) enhanced border security through portable biometric based checks, iii) secure person verification through real-time multi-source cross-referencing, iv) flexible, fast and cost-effective deployment of ad-hoc Border Check Points (BCP), v) secure, private and traceable sensitive / personal data exchange based on blockchain technology and vi) increased safety and improved experience for border-personnel based on advanced Human Machine Interfaces and enhanced situational awareness via Augmented Reality (AR). To achieve these ambitious goals, the FLEXI-cross project engages key European border authorities and end-users (police, port/rail operators, etc.) and brings them together with leading SW and technology developers, research organizations and innovative SMEs, to co-design the requirements and the solutions and to validate the project outcomes. This collaboration will drive the deployment of three state-of-the-art border-checking trial facilities, to enable real life trials in diverse operational environments, namely, vehicle-based road border crossing, rail-based border-crossing and port embarkation/disembarkation.

Keywords: secure border crossing,anti trafficking protection,anti smuggling protection,ad hoc deployment of border check point,biometrics,safe and private data management