Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Mapping the Cell (MAPPING THE CELL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2007-4-1-IOF, 2007)
Start date: 2009-03-01
End date: 2012-02-29
Duration (months): 36.0
Total project cost (EUR): 216237.32
EU funding (EUR): 216237.32
Participants: 1
Project status: CLOSED

A key challenge of systems biology is to understand how genes function as networks to carry out and regulate cellular process. Many important insights have emerged in recent years from studies using the yeast Saccharomyces cerevisiae. A partial genetic-interaction network has been compiled using double knockout mutations. Analysis of this network has provided many important insights about gene function and human genetics and disease. We will use reverse engineering principles to map cellular processes in yeast, in collaboration with the University of Toronto and the Sanger Institute. By disrupting an unknown process in diverse ways and observing the effects, a model for how the process works can be deduced. For this project, chemical compounds and genetic mutations will be used to perturb the yeast cell, and we will analyse their effects on growth rate. This ‘chemical genomic’ method has already been proven successful as it revealed important new connections in the DNA damage repair process in yeast. The Giaever and Nislow groups in Toronto have developed two chemical genomic assays called HIP and HOP assay which can measure the perturbation on the cell due to the presence of chemical probes. We plan to apply computational chemistry techniques to help streamline the process of finding and understanding the effects of new chemical probes using HIP and HOP screening technology. More importantly we will also apply bioinformatics techniques to extract meaningful network information from the results of the HIP-HOP assays.

Keywords: computational biology,bioinformatics,chemical genomics
Markov Chain Monte Carlo reconstruction of the large-scale structure with the Lyman alpha forest (MCMCLYMAN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-09-15
End date: 2010-09-14
Duration (months): 24.0
Total project cost (EUR): 153120.0
EU funding (EUR): 153120.0
Participants: 2
Project status: CLOSED

We address in this proposal the inverse problem for the reconstruction of the properties of the intergalactic medium based on the measured neutral hydrogen Lyman-α absorption observed in the spectra of high redshift quasars. We suggest the application of ARGO, a Bayesian sampling solver that has been developed by the applicant during his PhD thesis for the reconstruction of the large-scale structure and its properties based on galaxy redshift-surveys. This will permit for the first time to have a self-consistent reconstruction of all the relevant properties of the intergalactic medium. Some further developments are required in order to extent this work to the reconstruction of the intergalactic medium that should be implemented during this training. However, the numerical technology developed by the applicant A novel Krylov-space based inverse scheme included in ARGO allows for efficient reconstruction steps as is required for sampling purposes even in huge dimensional spaces. The cosmological information extracted from this study, such as the cosmological parameters is expected to be qualitatively better than in previous works in this field. This project should have major contributions in the understanding of galaxy and structure formation

Keywords: physical sciences,natural sciences,technological sciences
Atmospheric HumiditY DistRibution and the impAct of MIxing and TRAnsport in the free troposphere (HYDRAMITRA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-07-01
End date: 2010-06-30
Duration (months): 24.0
Total project cost (EUR): 153777.73
EU funding (EUR): 153777.73
Participants: 1
Project status: CLOSED

Understanding the processes that control the distribution of water vapour, the Earth's dominant greenhouse gas, is central to understanding climate. This project proposes to determine the combined effect of transport and mixing as well as micro-physical processes on the distribution of water vapour in the free troposphere. It will integrate theoretical knowledge acquired from idealised models with wind data sets and tracer measurements. The outcome of this approach is intended to contribute to a deeper understanding of the mechanisms controlling this distribution and thus to comprehend the implications of the corresponding structure on the radiative balance of the Earth.

Keywords: climate,water vapour,atmospheric transport,mixing,turbulence,chaotic advection,diffusion,lagrangian methods
Determinants of sexually antagonistic selection in a wild mammal population (SEXANTSEL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2007-2-1-IEF, 2007)
Start date: 2008-11-01
End date: 2010-10-31
Duration (months): 24.0
Total project cost (EUR): 168823.92
EU funding (EUR): 168823.92
Participants: 1
Project status: CLOSED

Selective pressures on males and females may be very different, leading to differences between the sexes (i.e. sexual dimorphism) in sexual ornamentation, weaponry, as well as body size, in many species. Such different selective pressures on males and females may result in sexually antagonistic selection on the two sexes: genes that are advantageous when expressed in males, may by disadvantageous when expressed in females. Given that sexual dimorphism is very abundant, it is likely that sexually antagonistic effects are very common in nature. Sexually antagonistic may have important implications for the maintenance of genetic variation and sexual selection in natural populations. However, the study of sexual antagonism is still in its infancy, and most evidence comes from laboratory studies. With this project I aim to make an important contribution to the study of sexual antagonism, by studying sexually antagonistic effects and their phenotypic and genetic determinants in a wild mammal population. I will use a multidisciplinary approach, combining advanced molecular genetics methods and ecological field data. The proposed project will furthermore be of vital importance to advancing my career as an independent researcher in ecological and evolutionary research.

Keywords: evolutionary biology,animal ecology,quantitative genetics,molecular ecology,sexually antagonistic selection,inter-sexual genetic conflict,sex linkage,natural populations,soay sheep
Swiss Network of Mobility Centres (SNMC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: MSCA other
Action type: Coordination and support actions
Countries involved: Switzerland
Call:  (FP7-Adhoc-2007-13, 2007)
Start date: 2008-06-01
End date: 2010-05-31
Duration (months): 24.0
Total project cost (EUR): 397900.0
EU funding (EUR): 199968.0
Participants: 1
Project status: CLOSED

Switzerland enjoys high quality research, research infrastructures and competent researchers. Europe, on the other hand, is the first priority co-operation partner for Swiss researchers. The enlargement of the ERA-MORE network to Switzerland by implementing SNMC is therefore more than desirable. Commitment in the European Mobility Strategy is a must for Switzerland. The Swiss Network of Mobility Centres SNMC will have a considerable impact on the Swiss Research Area. It will adapt Eracareers.ch (the Swiss network for researchers that is part of ERA-MORE) to the recent objectives of ERA-MORE. SNMC will enlarge Eracareers.ch, by positioning more Swiss research institutions optimally in the mobility network of the European Research Area. SNMC will thus contribute to a more consistent level of ERA-MORE support services across Europe and create new links between SRA and ERA. It will help balancing the number of researchers finding their scientific destination in ERA. The Rectors’ Conference of the Swiss Universities CRUS coordinates SNMC by addressing both, Swiss Higher Education institutions and industry, and proves ready to deal with future challenges to the universities. CRUS will manage the project SNMC and co-ordinate national structures. The CRUS back office will improve services provided to incoming, outgoing and returning researchers and their families, organise meetings and train Mobility Centre staff, create information and communication tools, revamp the national mobility portal, and do PR to raise awareness to the demands of mobile researchers. SNMC will lessen the drop out rate of researchers caused by mobility obstacles and support the probability of different kinds of researchers finding the workplace in which they can optimally develop their competence. It will contribute to the creation of an exciting and diverse ERA.

Keywords: enlargement of the era-more network to switzerland
Integrated control of neglected zoonoses: improving human health and animal production through scientific innovation and public engagement (ICONZ)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Collaborative project
Countries involved: United Kingdom,Belgium,Denmark,France,Germany,Portugal,Spain,Sweden,Switzerland,United Kingdom,Morocco,Mozambique,Nigeria,Uganda,South Africa,Tanzania, United Republic of,Zambia,Kenya,France,Mali,United Kingdom
Call:  (FP7-KBBE-2007-2A, 2007)
Start date: 2009-04-01
End date: 2014-12-31
Duration (months): 69.0
Total project cost (EUR): 7620060.54
EU funding (EUR): 5994998.0
Participants: 22
Project status: CLOSED

This project aims at Improving Human Health and Animal Production in developing countries through Integrated Control of Neglected Zoonoses in animals, based on Scientific Innovation and Public Engagement. Neglected zoonoses, such as anthrax, rabies, brucellosis, bovine TB, zoonotic trypanosomiasis, echinococcosis, cysticercosis and leishmaniasis, are major causes of ill-health in developing countries in Africa, Asia and Latin America. Production animals and companion animals of significant societal value act as reservoirs for transmission to man, and the burden of these diseases on affected communities is compounded by the adverse effects many diseases have on the productivity of livestock and hence the livelihoods of the poor. Control of these diseases in animals represents an opportunity to address the constraints they pose to both human health and animal productivity, thereby contributing to poverty reduction and the MDGs. Effective control in animals will require scientific innovation to identify and (where necessary) develop tools for diagnosis, for quantification of disease burdens, and for control. Public engagement at all stakeholder levels will be needed to ensure that strategies are appropriate for use in affected communities and are adopted within the policy framework of affected countries. The project will: (i) map and review research activities at a global level, (ii) survey and assess the burden of zoonoses in communities, (iii) improve or develop disease control tools as appropriate for conditions in affected countries, with private sector inputs where appropriate, (iv) develop cost-effective control and prevention strategies taking into account economic, sociological and cultural factors as well as traditional knowledge, (v) build capacity in ICPCs through technology transfer and training and (vi) empower communities and policy makers to utilise control and prevention strategies appropriately and effectively.

Keywords: anthrax brucellosis tuberculosis cysticercosis echinococcosis leishmaniasis rabies trypanosomiasis zoonosis
Nanoscale chemical imaging: Tools and techniques for localised infrared spectroscopy of nanostructured polymers and biomaterials. (NANOCHEMIMAGE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2007-2-2-ERG, 2007)
Start date: 2008-03-01
End date: 2011-02-28
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

The science of nanoscale structures and processes is currently an area of enormous activity, attracting great cross-disciplinary interest from researchers worldwide. This rapidly developing field requires novel tools and techniques for nanoscale analysis. The atomic force microscope (AFM) and scanning near-field optical microscope (SNOM), for example, have developed in response to this requirement. Recent work has demonstrated the potential of SNOM techniques to enable nanoscale infrared (IR) spectroscopy. Such a capability would be of immense value in understanding chemical processes at the nanoscale, such as those driving the self-assembly of materials or modifying protein conformation. Progress towards true nanoscale IR spectroscopy is, however, badly hampered by the lack of suitable widely-tuneable IR laser sources. The proposed reintegration grant will provide valuable supplementary support to five-year fellowship project, recently awarded to the researcher. This project addresses the development of suitable tuneable sources, based on nonlinear optical frequency conversion techniques, and their application to IR SNOM for the first time, thus enabling effective spectroscopic analysis of nanoscale objects. Collaborative studies of nanostructured materials and biomaterials will both validate the techniques developed and address important issues in the study of these systems. It is anticipated that the final outcome of this project will be a novel analytical tool of great value to nanoscale research in chemistry, physics and the materials and life sciences.

Keywords: tuneable lasers,near-field microscopy,infrared spectroscopy,nanostructured materials
OntoWiki – Semantic Collaboration for Enterprise Knowledge Management, E-Learning and E-Tourism (ONTOWIKI)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Germany,Austria,United Kingdom,Slovenia,Austria,Netherlands
Call:  (FP7-SME-2007-1, 2007)
Start date: 2008-11-01
End date: 2010-10-31
Duration (months): 24.0
Total project cost (EUR): 1469750.0
EU funding (EUR): 943800.0
Participants: 8
Project status: CLOSED

The aim of this project is to prepare and start-up the commercial exploitation of the semantic collaboration software OntoWiki in the three different target markets, namely Enterprise Knowledge Management, semantically enhanced content management for E-Learning and E-Tourism. OntoWiki is a comprehensive open-source platform for social semantic collaboration. It is developed at Universität Leipzig and has a large and active user base. Within the course of the project OntoWiki will be further developed and adopted to the needs of the SME for exploitation of OntoWiki in the prospective target markets.

Keywords: semantic web,owl,rdf,knowledge bases,social collaboration,web application,enterprise knowledge management,e-learning,e-tourism
New biocontrol agents for powdery mildew on grapevine (BCA_GRAPE)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Italy,Hungary,Italy,Hungary,Spain,Türkiye
Call:  (FP7-SME-2007-1, 2007)
Start date: 2008-07-01
End date: 2011-03-31
Duration (months): 33.0
Total project cost (EUR): 1001286.0
EU funding (EUR): 770000.0
Participants: 6
Project status: CLOSED

The main goal of the BCA_grape project is to develop prototypes of new commercial Biological Control Agents (BCAs) against Erysiphe necator, the fungus causing the powdery mildew of grapevine. The interest of the participating SMEs rises from the fact that this disease matches with their strategic need to increase the offer for crops and diseases not targeted by their currently available products: grapevine is a very interesting potential market; a large amount of fungicides is used to control powdery mildews; E. necator is a key pathogen in traditional, integrated and organic viticulture; the sole BCA currently available on the EU market is not effective enough. So far no reliable solutions exist for the non-chemical control of E. necator. The 6 partners (4 SMEs and 2 RTD performers) are settled in four EU countries; other countries and end-users are involved in some project activities. BCA_grape is organised in 9 Work Packages. RTD is mainly in charge to RTD performers but involves also the SMEs. Research is mainly addressed to: i) find new BCAs, highly effective and well adapted to the European conditions (WP1 and WP2); ii) develop a technology for the industrial mass production and formulation of the new BCAs (WP3); iii) develop protocols for the field application in order to maximize efficacy in both integrated and organic vineyards (WP4); iv) develop and validate a molecular protocol for BCAs identification in order to distinguish them, monitor their spread and survival in the vineyard, and trace their presence along the grape production chain (WP5). Demonstration activities (WP6) are aimed at validating the RTD results in commercial vineyards across Europe. An international congress, publications and a web-site are aimed at disseminating the results (WP7). Training for the SME staff is aimed at facilitating the take up of results (WP8). Management of the project activities, knowledge, IPR and exploitation of the results by the SMEs have a specific WP (WP9).

Keywords: grapevine,erysiphe necator,biocontrol agents,mycoparasitism,genetic markers,control strategies
Sustainable innovation technology in plant nursery process improving plant quality and safety (SITINPLANT)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: Italy,Greece,Bulgaria,Türkiye,Italy,Bulgaria
Call:  (FP7-SME-2007-1, 2007)
Start date: 2008-09-01
End date: 2011-02-28
Duration (months): 30.0
Total project cost (EUR): 1498600.0
EU funding (EUR): 1126400.0
Participants: 8
Project status: CLOSED

The quality of the plant material used to establish an orchard has a relevant importance for his success. Currently, in this sector, there is a widespread usage of chemical pesticides and of synthetic fertilizers, which are leading to the reduction of microflora complexity in the soil and decreasing the overall plant quality. There is the necessity of innovating plants’ production processes to produce plants more tolerant to common pathogens, and more efficient on using of natural soil resources in all phases of cultivation. The SITINPLANT project aims to work on these problems with te principal objective to improve the process in the fruit-growing nursery sector, based on a combined use of mycorrhizae and antagonist bio control microorganism for control disease incidence, and innovative micrografting technique. The final outcome of the developed process will be a mycorrhizzated and micrografted fruit tree, resistant to biotic and abiotic stress in nursery and orchard conditions. To achieve the project objectives, the following research targets will be carried out: * Development of the correct interaction methodology of mycorrhiza and antagonist bio control micro-organisms on controlling disease incidence and improving nutrient uptake in micrografting plants * Optimization of biotization techniques on rootstocks during their production in the micropropagation laboratory * Optimization of micrografting techniques * Optimization of growing techniques in the nursery of micrografted and mycorrizated plants * Implementation and testing of the innovated plant material in the different pedo-climatic conditions. The project positive impact will benefit the overall agriculture sector, as far as the productivity of the agriculture sector strongly depends on the quality of the plant after the nursery phase.

Keywords: micrografting
Open Source Modelling and Hardware Software Codesign of Embedded Systems (OSMOSIS)

Framework: FP7 — Capacities
Programme: Research for the benefit of SMEs
Destination: Research for SMEs
Action type: Research for the benefit of specific groups
Countries involved: France,Italy,Estonia,Greece,Greece,United Kingdom
Call:  (FP7-SME-2007-1, 2007)
Start date: 2008-10-01
End date: 2010-09-30
Duration (months): 24.0
Total project cost (EUR): 1420841.0
EU funding (EUR): 1030700.0
Participants: 6
Project status: CLOSED

Europe has a strong leadership in the domains of intelligent communications, multimedia, and automotive systems. However, the exponential increase in complexity threatens the European competitiveness. Current challenges when designing mixed HW/SW embedded systems are (1) mastering the complexity of the integration between the HW and the SW parts, (2) shortening time-to-market, and (3) reducing design cost. Codesign is the next big step in the holistic ( design of embedded electronic systems; hence it is an essential enabling technology for solving these challenges. It formalizes the interface between the hardware and software parts, and improves the amount of re-use, by allowing one to design models that can be adapted to several different performance/power/cost requirements and to different interface protocols. OSMOSIS will develop a key component required to maintain and enforce the European competitiveness in the intelligent system domains: create an open-source codesign framework for top-down embedded system design. This goal is achieved by joining the numerous on-going efforts in industry and academia into a unified best-practice, industrial-quality framework that will enable an easier transition from research results to industrial exploitation. The OSMOSIS platform will enable experimentation with codesign algorithms, starting from languages such as SystemC and producing HW and SW implementations. The results of the project will have a significant impact on intelligent embedded systems design by promoting cost-efficient software and hardware integration and reducing software/hardware concurrent development time. The consortium mobilizes a significant European force that covers the whole chain of embedded systems design: three embedded system design companies and silicon platform providers an arising research and development centre one of the largest European R&D centres and one prominent academic institution.

Keywords: hardware software codesign