Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Emotional Musical Signals (EMUSIG)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-06-30
Duration (months): 24.0
Total project cost (EUR): 191149.44
EU funding (EUR): 191149.44
Participants: 1
Project status: CLOSED

The emotional power of music is a force we reckon with on a daily basis. Bubbly music in advertisements entices us to buy products. Tranquil music in medical waiting rooms evokes calm and diffuses anxiety. In spite of its extensive influence, there are still many open questions about how music impacts our emotions. One emotion in particular has been largely overlooked in music and emotion research: fear. The lack of research is surprising given the important role fear plays in society. Fear-based mental disorders are the most widespread, negatively impacting the lives of millions worldwide. Fear drives our daily behaviors and thus is used frequently to spread beliefs for political gain. Given its relevance, there are many benefits for deepening our understanding of fear. Music, a powerful emotional influencer, could be the ideal tool for furthering our knowledge of fear. This groundbreaking, interdisciplinary action will unlock the potential of music as a platform for fear research through the combined use of methods from cognitive neuroscience, behavioral psychology, and music theory. Specifically, my research objectives are to create a new multicultural database of scary music excerpts, catalogue cultural and biological musical fear signals, and synthesize the results of this research into a comprehensive report on musical fear signaling. My training in music theory and cognition methods and my expertise in film music make me the ideal person for this action. The interdisciplinary, state-of-the-art research environment at the Cognitive and Affective Neuroscience Laboratory at the University of Zurich is the perfect location for this work. At this pioneering lab in the field of vocal and music perception, I will be trained in cognitive neuroscience methods (fMRI & eye tracking), statistical and programming skills, and in communicating my interdisciplinary work, fostering my development as an independent music cognition scholar capable of leading my own laboratory.

Keywords: music and emotion,vocal affective cues,film music,fear and the brain,fmri,eye tracking,topic theory
TOWARDS A 50% EFFICIENT CONCENTRATOR SOLAR CELL AND A 40% EFFICIENT SPACE SOLAR CELL (PVFIFTY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-01
End date: 2017-04-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Concentrator photovoltaic solar collectors have the potential to generate electricity at costs as low as 6¢/kWh, a price where they compete favourably with wholesale electricity prices. To achieve this, a solar cell with an efficiency in excess of 50% is required and will require considerable development over the present state of the art. In particular, a new semiconductor absorber layer with a 1eV band-gap will be required in addition to solar concentrations in excess of 1000X. The proposed research addresses both of these areas. Preliminary work has identified the use of bismide semiconductors to achieve the required 1eV semiconductor junction. A 1eV GaAsBi0.062 layer can be grown that has only 0.6% mismatch to GaAs, as compared to conventional In0.3GaAs that introduces >2% mismatch. We will develop high-performance photovoltaic devices based on this material. We will characterise the optical and electronic structure of these new materials using spectroscopic ellipsometry and photo/electroreflectance. The nature and concentration of defects will be determined using time-resolved optical spectroscopy and correlated with solar cell performance data by extending existing computer models. To achieve high efficiencies at high concentrations, it is necessary to reduce the resistive loss. Here, we propose to exploit lateral emission in tensile quantum well (QW) layers to provide a parallel radiative transport pathway that delivers photogenerated charges to the electrical contacts. A series of InGaP/InGaAsP QW test structures in compressive, tensile and unstrained configurations will be grown to control the directionality of emission, which will be confirmed using spectroscopic measurements. Concentrator solar cell device structures will be processed and the effective sheet resistivity evaluated using electroluminescent imaging. Front grid structures we be redesigned to account for radiative transport.
Consortium for Hall Effect Orbital Propulsion System – Phase 2 covering LOW POWER needs (CHEOPS LOW POWER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling advances in space technology
Action type: Innovation actions
Countries involved: Spain,Italy,Sweden,Belgium,Belgium,France,France,Netherlands
Call: SRC - In-space electrical propulsion and station keeping - Incremental technologies (H2020-SPACE-2020, 2020)
Start date: 2021-02-01
End date: 2025-01-31
Duration (months): 48.0
Total project cost (EUR): 5311430.0
EU funding (EUR): 4000000.0
Participants: 9
Project status: SIGNED

The LEO satellite market evolution sets a quick innovation pace for the satellite industry. High performances, compatibility with high production rates, adaptability and competitive prices are key in order to gain and maintain a strategic position. Based on a market analysis an EPS with a cost lower than 200K and a power range from 200W-1000W meets future satellite market needs, increasing European competitiveness on the worldwide satellite arena. CHEOPS Phase 2 LOW POWER will deliver incremental developments for the first fully European Low Power EPS bringing the Thruster Unit and the FMS to TRL7 and the PPU to TRL6. The system will be optimized with Xenon and compatible with Krypton. CHEOPS LOW POWER will permit the detailed design of the different system elements (TU, PPU, FMS) by addressing the following key challenges: compactness, modularity, optimized in-service life, low cost and high production rates, as well as flexible propellant management. Also, a multi-point qualification approach for the thruster unit enabling reduction of recurring costs through a more standard and common approach for all customers is considered. For this, CHEOPS LOW POWER will use a design to cost approach, COTS components and lean production approaches. CHEOPS LOW POWER will fully take advantage of new technologies and develop supporting advanced numerical design tools for electric propulsion, allowing to understand the observable behavior of a given thruster in its environment and predicting future performance. The project will achieve significant progress in setting a HET diagnostics standard thus preparing its implementation in the future In Orbit Demonstrator. CHEOPS LOW POWER will have a medium-term impact on the European space industry and its overall competitiveness by delivering a mature low power EPS. In the long-term the impact extends to the satellite design and manufacturing paradigm, enabling a novel approach integrating both industry and client needs since the start.

Keywords: competitiveness,constellations,digital twins
New Bus ReFuelling for European Hydrogen Bus Depots (NewBusFuel)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Research and Innovation actions
Partnership: FCH2 (Art-187)
Countries involved: Austria,Germany,Germany,Germany,Germany,Germany,Germany,Germany,Spain,Spain,Italy,Germany,Germany,Norway,Norway,Belgium,Latvia,United Kingdom,United Kingdom,United Kingdom,United Kingdom,Denmark,United Kingdom,United Kingdom
Call: Engineering studies for large scale bus refuelling (H2020-JTI-FCH-2014-1, 2014)
Start date: 2015-06-01
End date: 2017-03-31
Duration (months): 22.0
Total project cost (EUR): 2471144.75
EU funding (EUR): 2438919.27
Participants: 31
Project status: CLOSED

The overall aim of NewBusFuel is to resolve a significant knowledge gap around the technologies and engineering solutions required for the refuelling of a large number of buses at a single bus depot. Bus depot scale refuelling imposes significant new challenges which have not yet been tackled by the hydrogen refuelling sector: • Scale – throughputs in excess of 2,000kg/day (compared to 100kg/day for current passenger car stations) • Ultra-high reliability – to ensure close to 100% available supply for the public transport networks which will rely on hydrogen • Short refuelling window – buses need to be refuelled in a short overnight window, leading to rapid H2 throughput • Footprint – needs to be reduced to fit within busy urban bus depots • Volume of hydrogen storage – which can exceed 10 tonnes per depot and leads to new regulatory and safety constraints A large and pan-European consortium will develop solutions to these challenges. The consortium involves 10 of Europe’s leading hydrogen station providers. These partners will work with 12 bus operators in Europe, each of whom have demonstrated political support for the deployment of hydrogen bus fleets. In each location engineering studies will be produced, by collaborative design teams involving bus operators and industrial HRS experts, each defining the optimal design, hydrogen supply route, commercial arrangements and the practicalities for a hydrogen station capable of providing fuel to a fleet of fuel cell buses (75-260 buses). Public reports will be prepared based on an analysis across the studies, with an aim to provide design guidelines to bus operators considering deploying hydrogen buses, as well as to demonstrate the range of depot fuelling solutions which exist (and their economics) to a wider audience. These results will be disseminated widely to provide confidence to the whole bus sector that this potential barrier to commercialisation of hydrogen bus technology has been overcome.

Keywords: hydrogen buses,hydrogen bus refuelling depots,engineering studies,fuel cell bus commercialisation
Mechanisms of alternative pre-mRNA splicing regulation in cancer and pluripotent cells (MASCP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Spain
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2015-10-01
End date: 2021-03-31
Duration (months): 66.0
Total project cost (EUR): 2159574.0
EU funding (EUR): 2159574.0
Participants: 1
Project status: CLOSED

Alternative splicing of messenger RNA precursors is a prevalent form of gene regulation that greatly expands the coding capacity and regulatory opportunities of higher eukaryotic genomes. It contributes to cell differentiation and pluripotency and its deregulation promotes cancer progression, as evidenced by the frequent occurrence of cancer-associated mutations in splicing factors, which are also targets of anti-tumor drugs. Despite its prevalence and relevance, the underlying mechanisms of regulation remain poorly understood. This proposal aims to develop and apply systematic approaches that can allow us to carry out the equivalent of genetic analysis of splicing regulation in cancer and pluripotent cells. These technologies can help to unweave the complex network of functional interactions within the spliceosome and of the spliceosome with regulatory factors, exhaustively map the contribution of regulatory sequences and be used to investigate, with unprecedented detail, mechanisms of regulation for essentially any regulator or alternative splicing event operating in a particular cell line. Such approaches can offer a unique opportunity to address key unresolved mechanistic questions, including the molecular basis for positional effects of splicing regulatory factors (RNA Maps), the regulatory potential of the core spliceosome and the integration of alternative splicing with other cell regulatory programs. We will combine these approaches with biochemical and cellular assays to investigate detailed mechanisms of regulation relevant for the control of cell proliferation and/or pluripotency in cancer and induced pluripotent stem (iPS) cells. Progress in this area can contribute to reveal the molecular logic governing a key layer of gene regulation and has the potential to discover novel factors and regulatory circuits that trigger or modulate cell growth, differentiation and cancer progression.

Keywords: pre mrna splicing,alternative splicing,regulatory mechanisms,cancer cells,stem cells,reprogramming,rna profiling,gene networks
Revolving around the ubiquitin‒proteasome system: USP2-targeted degrader (USP2-TD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2023-09-30
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: SIGNED

Targeting DUB enzymes has recently emerged as a promising opportunity for drug discovery that might lead to more selective, less toxic drug profiles. Target validation of these enzymes is currently a priority in the field, as we are lacking of appropriate chemical probes for most of them. A clear example is USP2, whose chemical inhibition has been barely explored, leading to a poor-quality chemical probe that has been extensively used by biologist during the last decade. Hence, this multidisciplinary project emerges to address the identified unmet need of providing the scientific community with an appropriate chemical probe for a confident interrogation and further understanding of USP2 biology and disease. This probe will be useful for a suitable validation of this promising target and can eventually feed drug discovery projects for USP2-related cancer treatments. Herein, we aim to develop a, USP2-Targeted Degrader (USP2-TD) that overcomes the lack of selectivity and potency of its parent counterpart. This small-molecule USP2-TD will enable investigations of selective USP2 downregulation with exquisite quantitative and temporal control of protein levels. To this end, the proposed research deal with the identification of solvent-exposed region at the parent, the discovery of the USP2-TD, and its validation as chemical probe for USP2.

Keywords: deubiquitinases,ubiquitin specific protease 2,challenging protein targets,biophysics,chemical biology,chemical probe,targeted protein degradation,protacs,drug discovery
Seismic Investigation of Glacial and Magmatic Activity at Vatnajökull icecap, Iceland with implications for natural hazard monitoring in glacio-volcanic regions (SIGMA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Iceland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-03-01
End date: 2024-02-29
Duration (months): 24.0
Total project cost (EUR): 184239.36
EU funding (EUR): 184239.36
Participants: 1
Project status: CLOSED

Active ice-covered volcanoes present considerable danger to society due to their explosive, ash-rich nature and the potential to generate destructive glacial outburst floods. However, the ability to monitor their activity is complicated by the difficulty in discriminating volcanic and glacial earthquakes as they can appear identical in the seismic record. My recent work in Chile and Alaska has demonstrated how newly developed waveform correlation approaches could help distinguish between glacial and volcanic seismicity. The multi-disciplinary SIGMA project will apply these methods to an exceptional seismic dataset in Iceland while developing a new automatic classification software. The work plan includes creating a new micro-seismic catalogue in which events will be characterised as glacial or volcanic using statistical analysis tools. Furthermore, glacial events will be used to calculate subglacial hydraulic properties, an important requirement for modelling future glacier behaviour. The 3 targets areas across the Vatnajökull ice cap include some of the most active volcanic and glacial regions in Iceland. Under the supervision of Dr Magnússon and Prof. Aðalgeirsdóttir at the University of Iceland, and Dr Jónsdottír during a secondment at the Icelandic Meteorological Office, I will receive exceptional training in research and transferable skills that will allow me to fulfill my future career goal of becoming a leader in geophysical monitoring of volcanoes and other natural hazards. Being based at the University of Iceland will mean joining a world-leading research institute in geosciences with opportunities to develop internal and international multidisciplinary collaborations. Ultimately, the project will help future activity assessments at the most active volcanoes in Iceland and in turn, reduce their risk to local populations and infrastructure, while contributing towards the long-term EU target of ensuring a more resilient society against natural hazards.

Keywords: volcano seismology,cryoseismology,volcano monitoring
Investigating new policies for financial stability that do not create inequality (MACROPRU)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2023-09-30
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

The primary aim of the action is to investigate how new macroprudential policies can influence financial stability without contributing to inequality in society. In this project we aim to apply cutting-edge, agent-based simulation techniques to uncover the redistributive effects of macroprudential policies and to examine the combination optimality of the macroprudential tools from the social welfare perspective. The results of this project will complement the conclusions extracted from the ECB system-wide stress-testing exercises by providing data on the rise of inequality in EU countries due to the adoption of new financial regulations. It will also supplement the macroeconomic impact assessment for the Basel III reforms (cost-benefit "Growth-at-Risk" approach). This project expands our knowledge about a new, innovative tool, namely agent-based modeling, that can be used in financial oversight. It provides us with the practical knowledge of how to take into account the heterogeneity of the agents in the models and how to apply new Bayesian estimation techniques. The results of the project may guide policymakers and central bankers on how to reshape financial regulations and to calibrate macroprudential policies in order to minimize adverse social effects and to reduce inequality (by supporting a social policy). The project is consistent with the European Commission’s support on research programmes on the public sector and social innovation that is described in the Europe 2020 Flagship Initiative Innovation Union. The researcher will be fully integrated into Prof. J. Doyne Farmer’s team at the INET Oxford and at the Mathematical Institute of the University of Oxford. The Curie IF will give the applicant the opportunity to perform relevant and state-of-the-art research in the best institute of complexity economics in the world, to re-enforce her position as an independent research group leader and to initiate new long-term collaborations.

Keywords: central banking,financial stability,macroprudential policies,agent based modeling,simulation models with heterogeneous agents,redistributive effects,social welfare,inequality,stress testing
Improving IPR management services to SMEs engaging in peer learning activities (INPRO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Spain,Italy,Slovenia
Call: peer learning of innovation agencies (H2020-INNOSUP-2014-5, 2014)
Start date: 2016-08-01
End date: 2017-10-31
Duration (months): 15.0
Total project cost (EUR): 50000.0
EU funding (EUR): 50000.0
Participants: 3
Project status: CLOSED

Within the INPRO project, the involved partners wants to peer review IPR support programmes for SMEs in order to improve their knowledge and attitude towards this important topic as well as to transfer good practices into regional/national programmes. Using the Twinning Advanced methodology, the Design Options Paper (DOP) on IPR services to SMEs will be elaborated in order to be at disposal for other innovation agencies to design and/or deliver similar IPR services. Professional experts with extensive knowledge and experience on IPR and on creative moderation methodologies will be subcontracted to moderate the two peer learning workshops in order to achieve the highest quality results. The peer learning group will be composed by 12 persons from the 3 Regions/Country involved (Friuli Venezia Giulia region – Italy; Spain; Slovenia). The aim of the working group will be to strengthen the IPR support services and programme design through the application of the Twinning+ methodology. The INPRO project will facilitate the knowledge exchange among the participants on the following matters: • Provision of the IPR support services to SMEs on the involved territories and focus on the major experienced difficulties; • Identification of “good practices” applied by the partners and “good practices” available at EU level to be transferred in the involved territory; • Improvement of IPR support services to SMEs; • Enhancement of qualitative procedures in IPR auditing; • Improvement of the administrative aspects in the IPR management both at SME level and PA level. A Memorandum of Understanding (MoU) will be undersigned by the partners at the end of the project with the aim to engage in more frequent peer learning activities. The MoU should be a first step of an EU based network of partners aiming to foster, enforce and further develop IPR services to SMEs.

Keywords: innovation support services,creative industries,smes,design,trademark,patent