Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Metal-Organic Cages for Catalysis Applications (MOCCA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-01
End date: 2020-04-30
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

The formation of all carbon-based materials in nature starts with fixation and transformation of carbon dioxide (CO2) into useful chemical compounds. Such reactions are enabled by enzymes which often contain highly active metals as reaction centers that are deeply buried in a protein. In contrast, fine chemical production in industry is nowadays still mainly dependent on fossil fuels as carbon feedstock. Since fossil fuels are a limited resource there is an urgent need for alternative strategies. MOCCA (= Metal Organic Cages for Catalysis Applications) aims for the direct use of CO2 to functionalize olefins and produce higher carbon compounds. Principles from nature will be applied such as incorporation of metal catalysts inside a discrete cavity that allows specific substrate binding and activation. The process is divided into two steps: (1) CO2 reduction and (2) insertion of reaction products into the double bond of olefins, for example by hydroformylation. Both reactions are of high interest in chemical research and industry; several metal complexes have been reported as catalysts. Metal complexes are easily tunable via ligand design and molecular catalysts featuring active site mimics have been prepared. However, the current generation of these systems cannot compete with the efficiency of enzymes. Today it is clear that drastically simplified active site mimics do not fulfill all necessary conditions for keeping up with their natural paradigms, but also the outer shell plays an important role. Thus, the need for wrapping catalytic sites in a tunable chemical environment is evident. The nowadays available toolbox of design-driven supramolecular self-assembly allows the construction of such tailored environments, while investigation of encapsulated catalysts is still in its infancy. MOCCA will demonstrate the first example of molecular coordination cages containing catalysts as linkers that efficiently reduce CO2 and use the reaction products directly for the pro

Keywords: supramolecular chemistry,co2 reduction,hydroformylation
FUTURE ALL AVIATION CNS TECHNOLOGY (FACT) (FACT)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Germany,Italy,Germany,Türkiye,Türkiye,Belgium,Czechia
Call: Innovation in CNS to enable Digitalised Operations (H2020-SESAR-2019-2, 2019)
Start date: 2020-07-01
End date: 2022-12-31
Duration (months): 30.0
Total project cost (EUR): 2073558.75
EU funding (EUR): 1850500.0
Participants: 8
Project status: CLOSED

The project FACT (Future All Aviation CNS Technology) relates to SESAR-ER4-24-2019: Innovation in CNS to enable Digitalised Operations. It addresses all application areas listed in the Call Topic 24, except the area 4 (Manned and un-manned aircraft protection from non-cooperative targets). It will bring a much needed update to CNS technology, and build the bridge between future U-space services (expecting fully digital and highly automated) and conventional ATM systems considering both technological and users’ perspectives. The main overall objective(s) of the project FACT is to increase safety, security, efficiency, and robustness of future air traffic environment through development of integrated CNS functional architecture supporting the use of common performance based approach for CNS functions addressing needs of large spectrum of airspace users across varied operational environments. It will address and bring benefits for both existing and new airspace users such as drones or urban air mobility. From technical perspective, the project will mainly focus on the innovative use of existing technology bricks, potentially adapted from adjacent industrial areas such as automotive or telecommunication. Interesting examples of such new CNS enablers are the envisioned use of 3G/4G/5G for communication and localization, OneWEB for low cost satellite communication, or Aeromacs as a new technology standardised by aviation for airport operations. This approach will allow the project to achieve technical performance goals at a lower development cost, and offer something that can find the aviation market in the shortest possible time. The project consortium brings together a balanced combination of industrial, operational, and academic knowhow, enabling it to address this challenging task.

Keywords: gnss,ads b
Majoration-Minimization algorithms for Image Processing (MAJORIS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: France
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-01-01
End date: 2025-06-30
Duration (months): 66.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Mathematical optimization is the key to solving many problems in science, based on the observation that physical systems obey a general principle of least action. While some problems can be solved analytically, many more can only be solved via numerical algorithms. Research in this domain has proved essential over many years. In addition, science in general is changing. Increasingly, in biology, medicine, astronomy, chemistry, physics, large amounts of data are collected by constantly improving signal and image acquisition devices, that must be analyzed by sophisticated optimization tools. In this proposal, we consider handling optimization problems with large datasets. This means minimizing a cost function with a complex structure and many variables. The computational load for solving these problems is too great for even state-of-the-art algorithms. Thus, only relatively rudimentary data processing techniques are employed, reducing the quality of the results and limiting the outcomes that can be achieved via these novel instruments. New algorithms must be designed with computational scalability, robustness and versatility in mind. In this context, Majorization-Minimization (MM) approaches have a crucial role to play. They consist of a class of efficient and effective optimization algorithms that benefit from solid theoretical foundations. The MAJORIS project aims at proposing a breakthrough in MM algorithms, so that they remain efficient when dealing with big data. I propose to tackle several challenging questions concerning algorithm design. These include acceleration strategies, convergence analysis with complex costs and inexact schemes. I will also tackle practical, massively parallel and distributed architecture implementations. Three specific applications are targeted: super-resolution in multiphoton microscopy in biology; on-the-fly reconstruction for 3D breast tomosynthesis in medical imaging; and mass spectrometry data processing in chemistry.

Keywords: inverse problems,majorization minimization methods,image processing,large scale optimization,parallel computing,tomographic reconstruction,image deblurring,sparse signal restoration,convergence analysis,non convex optimization
Establishing services enhancing the innovation management capacity of SME´s in Hamburg and Schleswig-Holstein (INNOKAM 2020-21)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Germany,Germany
Call: H2020 ENTREPRISE EUROPE NETWORK SGA4 2020-2021 (H2020-EEN-SGA4-2020-2021, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 249912.5
EU funding (EUR): 249912.5
Participants: 4
Project status: CLOSED

The four partners Investitionsbank Schleswig-Holstein (IB.SH), TuTech Innovation GmbH (TuTech), Wirtschaftsförderung und Technologietransfer Schleswig-Holstein (WTSH) and IFB Hamburg (IFB) are part of the Enterprise Europe Network (EEN) consortium in Hamburg and Schleswig-Holstein and established a well-known regional one-stop-shop for all EUrelated enquiries for SMEs and regional stakeholders. For the period 2020-21 core objective is to expand the client base and deepen the level of assistance by offering the service of “Key Account Management” (KAM) and “Enhancing SME Innovation Management Capacity” (EIMC). Aim is to face existing lack of innovation management capacity in small and medium sized companies (SME) and support their innovative activities in order to creating economic impact. The guiding principle is that the services are tailored to the needs of the identified regional innovators and innovation systems. In this context the KAM is targeted at beneficiaries of the EIC Pilot under Horizon 2020, the EIMC addresses other highly innovative SMEs. The EIMC helps companies to establish effective innovation management systems that enhance the realisation of growth opportunities. The KAM focuses on those weaknesses which endanger the success of the funded project. It assists in finding specialised coaches and establishing a coach-client relationship. Both approaches aim to raise the company´s competitiveness and profitability. In the framework of the project the consortium acquired user licenses for the IMP3rove tool in order to assess gaps and needs of the SMEs. In this context senior staff of the EEN attended training to ensure that the tool is used correctly and the assessment exercise complies with the envisaged EU standard. In addition the participation in training courses gives the chance for a best practice exchange with other EEN colleagues and is of great benefit for the consortium.

Keywords: innovation management capacity,key account management,sme instrument,enterprise,europe netowork,hamburg and schleswig holstein,germany
CHIRALSENSE : Sensing Chirality using cavity-enhanced polarimetry: advances in sensitivity and time-resolution (CHIRALSENSE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Greece
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-04-01
End date: 2016-09-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Chiral sensing is crucial to many fields, constituting a multibillion Euro industry. The polarimetric techniques of optical rotation (OR) and circular dichroism (CD) are the most widely-used techniques for the analysis of chiral samples, ranging from the measurement of protein structure, to quality control in the pharmaceutical, chemical, cosmetic, and food industries. In general, the OR and CD signals are very small, which place severe constraints on detection sensitivity and time-resolution. Through the ERC grant TRICEPS, we have developed a groundbreaking cavity-based polarimeter [Sofikitis et al. Nature 514, 76 (2014)] with 3 main advantages: (a) The OR and CD signals are enhanced by the number of cavity passes (typically 1000); (b) birefringent backgrounds are suppressed; (c) signal reversals give absolute polarimetry measurements, not requiring the sample to be removed to measure a null sample. These advantages represent orders-of-magnitude improvements in sensitivity, acquisition time, and sample size, with respect to commercially available polarimeters, and will reduce measurement time, sample sizes, and costs in the chiral sensing industry. We propose, through CHIRALSENSE, to: (1) file a non-provisional US patent application, to follow our filing of a US provisional patent application for our polarimeter, which will provide IPR protection for the first stages of the product development; (2) demonstrate our existing CHIRALSENSE polarimeter to leading polarimetry companies, by performing measurements on commercial-standard samples; and (3) adapt our polarimeter to measure complex samples separated using HPLC (high-performance liquid chromatography) for analytical chemistry applications, to be demonstrated to leading HPLC companies.

Keywords: chiral sensing,circular dichroism,optical rotation,optical rotary dispersion,polarimetry,cavity ringdown,cavity enhancement
Multi stakeholder and governance approach for SECAP development and implementation (PentaHelix)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Spain,Spain,Belgium,Norway,Belgium,Belgium,Croatia,Latvia
Call: Engaging and activating public authorities (H2020-EE-2017-CSA-PPI, 2017)
Start date: 2018-03-01
End date: 2021-09-30
Duration (months): 43.0
Total project cost (EUR): 1808343.75
EU funding (EUR): 1808343.75
Participants: 12
Project status: CLOSED

The PentaHelix project is focusing on developing and testing a new approach for integrating multi-governace planning for sustainable energy, both horisontal and vertical, togeheter with a close interaction with key stakeholders in energy efficiency and sustaianble energy solutions such as the industry and business, building sector, NGO's, academia and individual citizens or relevant associations. The project aims at developing a peer-to-peer online platform for SECAP development that can be used for multiple public authorities in joint planning and implementation. This will enable the integration of different administrative levels and geographical planning areas as well as enhance the cost efficiency in the entire planning and implementation process based on economic of scale and closer cooperation and exchange. In addition regional PentaHelix Task forces will be established, involving key stakeholder and target groups, that will serve as a driver for a wider scope of the SECAPs as well as bringing in valuable insights and identification of potential measures, system solutions and a better understanding of drivers and barriers for a more sustainable society as a whole, in each specific region. This PentaHelix approach will be developed and tested in 8 pilot municipalities in Norway, Croatia, Belgium, Spain and Latvia. Each region is unique in terms of demography, economy, urban development, climate conditions and industrial/ businesss structure. Together these pilot areas consititutes a large number of inhabitants and potential mitigation of CO2 and energy savings. To further enhance the impact of the project a broad replication and dissemination strategy and actions will be rolled out in many countries in the EU. This will be mainly carried out towards neighboring regions as well as the network of ERRIN with it's many member organisations. Targeted dissemination actions will be implemented. 11 partners from 5 countries will do this during 43 months.

Keywords: secap,multi governace,public authorities,stakeholders,planning,energy planning,sustainble
Ser-Col; from finger to laboratory; personalized and automated serum collection for laboratory diagnostics (SCAUT)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Armenia,France,Netherlands
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2018)
Start date: 2019-01-01
End date: 2022-03-31
Duration (months): 39.0
Total project cost (EUR): 3984850.0
EU funding (EUR): 2998374.0
Participants: 4
Project status: SIGNED

95% of blood collected via venipuncture is not used for diagnostic measurements, and needs to be disposed as biohazardous waste by incineration, which is incredibly wasteful and taxing on our environment. In Europe, there is an urgent need for innovative approaches that engage vulnerable groups and increase access to infectious disease testing by breaking-down social and logistic barriers to healthcare. The decentralization of healthcare have created a need for a simple, safe, standardized and painless collection of serum specimens. The Ser-Col® is a novel serum separation device that simplifies and combines both blood collection and serum separation. With a few drops of blood from a finger stick, serum can be collected which is stable for several months prior to analysis of clinically relevant serum parameters, and thereby reducing biohazardous waste production by 50%. Ser-Col simplifies and reduces the cost of serum sampling by replacing the blood tube, trained personnel, cold storage, and centrifuge with a reliable and easy to use device that links target population to centralized diagnostics laboratories, ultimately leading to the long-term reduction of the burden of infectious diseases. The SCAUT consortium will scale up manufacturing to deliver a market ready version of the Ser-Col and validate its clinical performance against existing standards. To ensure market uptake the consortium will develop an automated serum processing platform for optimal compatibility with exciting laboratory diagnostic equipment and facilitate adoption of Ser-Col by healthcare professionals. This will accelerate commercialization, attract investors and to establish industry partnerships required to realize the full potential of the technology. The SCAUT project seeks to obtain €3 million to finalize the analytical and clinical validation and go-to-market of the Ser-Col® device. The estimated cumulative profit is €463.813 in 2023 increasing towards €18 million in 2027.

Keywords: clinical chemistry,serum analysis,sustainability,automation
Mimicking the dynamic and complex ECM: designing bioprinted immune-instructive hydrogels (INKspired)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-15
End date: 2023-09-14
Duration (months): 24.0
Total project cost (EUR): 175572.48
EU funding (EUR): 175572.48
Participants: 1
Project status: SIGNED

Tissue and organ shortage is the limiting factor in treating many patients with chronic organ failure and has led to over 18 patients deaths every day just in Europe. Recreating the 3D complexity of tissues and organs is moving step-by-step from sci-fi to reality thanks to the tremendous progress in 3D printing techniques. Native tissues and organs are composed of different cells, proteins, and signaling molecules that are arranged in a hierarchical complex microenvironment, called extracellular matrix (ECM). Bioprinting has emerged as a novel fabrication technique that assembles cells-laden biomaterials in a spatially controlled manner, promising customized 3D tissue-engineered constructs for potential clinical use. One of the main challenges to clinical success is to avoid immune system rejection. The overall aim of the INKspired project is to generate novel ECM-inspired bioinks, which could further recapitulate the dynamicity and complex structure of native tissue and even modulate the immune response. By double network strategy, I will combine two dynamic hydrogel networks to control the overall mechanical and biological properties of printed constructs. The outcomes of INKspired aim to contribute to tissue bioprinting and hence the global chronic lack of tissues. My unique research background, which includes tissue engineering, material science and engineering, will allow me to carry out this multidisciplinary project. I will collaborate with the supervisors, who have a vast experience in biofabrication and biomaterials, and work at the international and interdisciplinary setting (MERLN, Maastricht University). Marie Curie fellowship will enhance the potential of my future career perspectives by providing an interdisciplinary and translational education program, empowering me to take leading positions in the field of tissue engineering worldwide.

Keywords: bioprinting,dynamic covalent chemistry,instructive hydrogels,photo switchable polymers,tissue engineering
ROTATION HEAT PUMP – the refrigerant free highly-efficient heat pump for industrial use (Rotation Heat Pump)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Austria
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2018-08-01
End date: 2021-03-31
Duration (months): 32.0
Total project cost (EUR): 2630000.0
EU funding (EUR): 1750000.0
Participants: 1
Project status: CLOSED

The Austrian tech company ecop Technologies GmbH concentrates on R&D and manufacturing of an innovative Rotation Heat Pump. The Rotation Heat Pump uses a disruptive technology, patented several times, with a completely new physical approach based on a 1-phase thermodynamic cyclic process instead of the thermodynamic 2-phase compression process of conventional heat pumps. This, for the first time, enables high-scale industrial use that existing conventional heat pumps cannot provide because their process is not suitable for high temperatures and fluctuating conditions of industrial settings. Furthermore, they usually require as working fluids refrigerants with a high global warming potential (GWP), while the Rotation Heat Pump uses an inert gas with GWP zero, widely available, inexpensive and not posing any security issues. The objective of this innovation project is to bring the Rotation Heat Pump to the market. Transfer from TRL7 to 8 of the currently existing 700 kW technology includes enlarging the temperature range to 150°C, fine-tuning the control system, raising energy efficiency and reducing production costs. In parallel, the optimized Design of a cost optimized Rotation Heat Pump will be conducted. Additional demo plants – one already existing in district heating – shall demonstrate further important use cases like industrial drying. Implementing a profound communication strategy and partnering with system integrators at EU level will pave the way to commercialization. Impacts mare of high importance for a low carbon and efficient energy system and circular economy approaches in line with the respective EU policies: The Rotation Heat Pump enhances energy efficiency of (district) heat nets by 40% and allows highefficient usage of waste heat potentials (in many sectors e.g. for industrial drying). Future applications will for instance enable Power-to-Heat storage systems for boosting renewables.

Keywords: joule process,gwp zero,heat pump,f gas regulation