Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
European Forum for a Comprehensive Vision on Urban Agriculture (EFUA)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Coordination and support actions
Countries involved: Germany,Italy,Italy,Italy,Germany,Belgium,Bulgaria,Netherlands,Denmark
Call: A comprehensive vision for urban agriculture (H2020-FNR-2020-1, 2020)
Start date: 2020-11-01
End date: 2024-10-31
Duration (months): 48.0
Total project cost (EUR): 2039437.5
EU funding (EUR): 2039437.5
Participants: 11
Project status: SIGNED

EFUA’s objectives are to unlock Urban Agriculture’s potential by achieving better knowledge, better deployment, and better policies in this field. By setting up an UA Forum it aims to develop a new level of stakeholder engagement to better inform decision making and turn Urban Agriculture into a European, regional and local policy domain. EFUA will contribute to the work programme by defining next practices and stakeholder based R&I programmes for Urban Agriculture and also by investigating its role as an innovator in the agricultural and food sector and the urban bioeconomy. UA is a thriving subject, globally, but has not made its way into European policies due to barriers resulting from gaps in both knowledge and advocacy. EFUA will overcome these barriers by establishing the UA Forum, thereby allowing a new level of stakeholder engagement, co-building of knowledge, better deployment and specifically targeted policies. The UA Forum is set up following a quad helix approach and as durable format to ensure ongoing networking in Urban Agriculture and to give European policies a partner to better support UA in the long term. EFUA’s workflow is organized in three loops culminating in 3 public conferences and the co-design of a UA vision. EFUA’s work is facilitated by the UA platform offering various tools for engaging stakeholders and co-building of knowledge together with the UA Forum, but also for communication and dissemination. Special networking methods are used to access cutting edge knowledge from R&I projects to define next practice of Urban Agriculture. Benefits of Urban Agriculture and recommendations for action are targeted to European policy makers thereby supporting various agendas and programs. Impact is increased by target audience oriented communication, making use of excellent dissemination channels. Impact is sustained by perpetuating the UA Forum’s work.

Keywords: cost action uae,european policies
Enhancing the innovation management capacity of SMEs through the Enterprise Europe Network in Macedonia (INNO EEN-M) (INNO EEN-M)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: North Macedonia,North Macedonia
Call: H2020 ENTREPRISE EUROPE NETWORK SGA4 2020-2021 (H2020-EEN-SGA4-2020-2021, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 19260.0
EU funding (EUR): 19260.0
Participants: 3
Project status: CLOSED

The general objective of the INNO EEN-M project is to increase the economic returns from innovation and enhanced innovation management capacities of the Macedonian SMEs through offering a standardized set of coaching and innovation management services while ensuring synergy with other services of the Enterprise Europe Network in Macedonia (EEN-M). The project aims to deliver 28 (twenty-eight) 7-day service packages: 24 package services will be provided to SMEs with significant innovation activities and high potential for internationalization and 4 packages for the SME beneficiaries of the EIC pilot under H2020. As the national consortium is responsible for providing services at whole territory of the country, this project will also cover the same area. The services will be delivered by three innovation experts/Key Account Managers (KAM) from UKIM, member of EEN Macedonia. The INNO EEN-M project is highly related to the call for Enterprise Europe Network – Horizon 2020 (2020-21) and will provide necessary tools, knowledge and experience to the EEN-M for implementation of the specific activities in the context of innovation support. The activities within the project are organized in two work packages: key account management (KAM) for SME beneficiaries of the EIC pilot under H2020 and enhancing SME innovation management capacities for innovating SME independently from a specific project. The selection of SMEs will be done based on identified criteria whereas services will be delivered in line with the specific common format with the packages. The team will use the IMP³rove tool as an assessment tool. The KAM will undertake needs analysis/coachcom tool to support SMEs in selection of lead coach. The planned duration of both work packages is 24 months (2020-21). The services, benefits and experiences from these activities will be part of internal evaluation.

Keywords: innovation,smes
An integrative approach to uncover the multilevel regulation of 20S proteasome degradation (20SComplexity)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Israel
Call: ERC Starting Grant (ERC-2014-STG, 2014)
Start date: 2015-04-01
End date: 2020-03-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: CLOSED

For many years, the ubiquitin-26S proteasome degradation pathway was considered the primary route for proteasomal degradation. However, it is now becoming clear that proteins can also be targeted for degradation by a ubiquitin-independent mechanism mediated by the core 20S proteasome itself. Although initially believed to be limited to rare exceptions, degradation by the 20S proteasome is now understood to have a wide range of substrates, many of which are key regulatory proteins. Despite its importance, little is known about the mechanisms that control 20S proteasomal degradation, unlike the extensive knowledge acquired over the years concerning degradation by the 26S proteasome. Our overall aim is to reveal the multiple regulatory levels that coordinate the 20S proteasome degradation route. To achieve this goal we will carry out a comprehensive research program characterizing three distinct levels of 20S proteasome regulation: Intra-molecular regulation- Revealing the intrinsic molecular switch that activates the latent 20S proteasome. Inter-molecular regulation- Identifying novel proteins that bind the 20S proteasome to regulate its activity and characterizing their mechanism of function. Cellular regulatory networks- Unraveling the cellular cues and multiple pathways that influence 20S proteasome activity using a novel systematic and unbiased screening approach. Our experimental strategy involves the combination of biochemical approaches with native mass spectrometry, cross-linking and fluorescence measurements, complemented by cell biology analyses and high-throughput screening. Such a multidisciplinary approach, integrating in vitro and in vivo findings, will likely provide the much needed knowledge on the 20S proteasome degradation route. When completed, we anticipate that this work will be part of a new paradigm – no longer perceiving the 20S proteasome mediated degradation as a simple and passive event but rather a tightly regulated and coordinated process.

Keywords: 20s proteasome,protein degradation,macromolecular complexes,native mass spectrometry
Role of the mucin-like domain of the Ebola virus in modulating virus-glycosaminoglycan interactions (REMIND EBOV)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-08-01
End date: 2023-08-16
Duration (months): 24.0
Total project cost (EUR): 191852.16
EU funding (EUR): 191852.16
Participants: 1
Project status: SIGNED

Ebola virus, one of the deadliest human pathogens, is a known candidate for severe outbreaks and has caused several thousand deaths in the more recent outbreaks alone. To fight against it, a detailed knowledge about its viral life cycle is fundamental to the development of efficient vaccines and drugs. In this project I suggest to investigate the role of the mucin-like domain (MLD) of the viral glycoprotein (GP) in modulating virus attachment, detachment and diffusion on glycosaminoglycans (GAGs), responsible for recruiting the virus at the cell surface. To do so, I will generate GP-containing pseudotyped viruses, mimicking the tropism of the pathogen. Specifically, I will compare the GP of the Zaire strain of EBOV, an MLD-deleted mutant and a natural mutant that occurred during the West Africa outbreak (2013-2016) that is reported to have an increased tropism for human cells. I will use advanced biophysical techniques to examine the interactions on a molecular level as well as on the cellular level. On a molecular level, I will study the binding strength of individual bonds formed between the GP and GAGs using force spectroscopy. In addition, I will investigate the attachment and detachment of virus particles from GAGs immobilized on a glass surface in a biomimetic fashion, using total internal fluorescence microscopy. Proceeding to a more physiological model using living cells, I plan to study the diffusion behavior at the cell surface of pseudotyped viruses carrying the various mutations in their MLD. Stepping up in complexity, in the last part of the project, I will investigate the role of the MLD in modulating the ability of the virus to cross the glycocalyx, the sugar coat of cells, by employing 3D tracking. Taken together this project will lead to a better understanding on how viral particle migrate on the cell surface and how the interactions function on a molecular level.

Keywords: ebola virus,virus diffusion,virus membrane interactions,glycoaminoglycans
EuroMED Cooperation. Inland and Marine Water Challenges (EuroMED-IMWC)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Coordination and support actions
Countries involved: Italy
Call: Europe (H2020-Adhoc-2014-20, 2014)
Start date: 2014-07-01
End date: 2014-12-31
Duration (months): 6.0
Total project cost (EUR): 125500.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The project supports the organization of the Italian Presidency event ‘EuroMED cooperation. Inland and Marine Water Challenges’, strongly emphasizing Mediterranean cooperation on research and innovation. In the framework of the ENP and the UNEP/MAP Barcelona Convention and in line with H2020 work-programme, the event is designed as a two day conference embracing present political debate for the identification of urgent challenges to advance the frontier of science and to foster technological innovation to sustain economic growth and EuroMED cooperation. The event - to be held in Naples in September 2014 - offers the unique opportunity to underline the links between inland and marine waters, with special emphasis to the impacts that such a link has on society and economic growth, particularly in a Region whose relevant economic activities like fishery, agriculture, and coastal and marine tourism are clearly affected by the water management issue. As milestone towards the definition of a roadmap to tackle these objectives, on the first day four parallel workshops will address: (1) Water resources and land management impacts on inland and sea water in the Mediterranean Region; (2) A Mediterranean integrated Ocean observing system to support sustainable coastal and marine tourism; (3) Building Ecosystem based approach to Fishery and Aquaculture in the Mediterranean Sea; (4) Ecosystem-Based Management (EBM) in the Mediterranean Region. On the second day, a plenary session will finally deliver the key output message. In order to guarantee the effectivness of the event, different stakeholders from public and private sector will actively be involved in the organization, including policy makers at Ministry level and private companies. Besides Member States and international organizations, a broad participation of representatives from non-EU countries is expected. To maximize the impacts strong efforts will be also devoted to communication and dissemination activities.

Keywords: mediterranean region,cooperation,ecosystem based management,water,tourism,fishery and aquaculture
Traditional Organised Crime and the Internet: The changing organization of illegal gambling networks (OCGN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-05-22
End date: 2018-11-21
Duration (months): 18.0
Total project cost (EUR): 146591.1
EU funding (EUR): 146591.1
Participants: 1
Project status: CLOSED

Transnational criminal networks utilise Information Communication Technology (ICT) to commit ‘old’ and ‘new’ types of crime. ICT assists in transnational crime (i.e., hacking) and also as a way to exchange information or plan new crimes. Empirical research has provided ample evidence that social and familial networks play a crucial role in the formation and growth (recruitment) of criminal networks. However, ICT now makes it possible for organised crime to form networks without the restrictions of geographic proximity and with the growth in the online gambling sector estimated at 13 billion Euros per annum in the EU worth approximately 15 percent of EU gambling market such sums of revenue attracts unwanted attention from organised cybercriminals. This proposal will therefore examine online gambling and extortion networks. The reason(s) for this is that gambling – illegal and legal – has often attracted organised crime, and empirical evidence regarding online gambling and extortion in EU is limited. The objectives of this research are: establish tools and technique that facilitate management of internal/external cyber-threats to online gambling sector validate tools and techniques that will facilitate the management of internal/external cyber-threats to online gambling sector set standards of information management set standards of dissemination and flows of information to cybersecurity centres from online gambling sector in EU This is to be achieved by: interviews with key individuals (systems managers at online sites and law enforcement) analyse data for information flows and breaking down volume of information into accessible data for internal and external use. analyse current decision making processes/systems and processing information analyse exchange of data to improve and implement best practice available in cybersecurity across EU online gambling sites

Keywords: gambling,organised crime,criminal networks
Implementation of early detection and early intervention service delivery in infants at risk for cerebral palsy to promote infants’ psychomotor development and maternal health (BornToGetThere)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Health care provision and integrated care
Action type: Research and Innovation actions
Countries involved: Australia,Italy,Italy,Georgia,Netherlands,Sri Lanka,Denmark
Call: Implementation research for maternal and child health (H2020-SC1-2019-Two-Stage-RTD, 2019)
Start date: 2020-01-01
End date: 2023-12-31
Duration (months): 48.0
Total project cost (EUR): 4010000.0
EU funding (EUR): 3700000.0
Participants: 9
Project status: SIGNED

Despite advances in the medical management of high-risk pregnancies and deliveries, cerebral palsy (CP) remains the most common physical disability in childhood in high and low-to-middle income (LMIC). In addition, caregivers of children with CP are at higher risk of psychiatric issues, further increasing health and socio-economic burden to the families. In spite of the scientific advancements in early detection and intervention (EI) in CP, there is a lack of implementation into clinical service delivery. The overarching aim of the BORNTOGETTHERE program is to exploit current evidence on early detection and efficacy of EI for infants at high risk of CP by implementing the International Clinical Practice Guideline in Europe (Italy, Denmark, Netherlands), LMIC (Georgia, Sri Lanka) and hard to reach populations (Remote Queensland and Western Australia). It will provide a multifaceted knowledge translation approach focused on i) optimizing context-specific health programs for early detection of CP, thus reducing age at diagnosis and age at referral to EI; ii) optimizing early functional characterization of infants with CP, thereby fostering personalized EI and preventing secondary complications (i.e. hip dislocation) and iii) testing the implementation of integrated EI programs adapted to country-specific welfare systems. The protocol of service delivery will result from the adaptation of early detection and EI programs based on the proven, effective intervention strategies, and those that are included into ongoing research based on effectiveness shown with preliminary data. This framework will be validated in real life varying world conditions through a large implementation program and a multicentre parallel controlled trial. The main beneficiaries will include a wide range of stakeholders: not only concerned families and communities but also policy makers, public authorities, the media, and citizen groups to ensure the translation of evidence into routine practice.

Keywords: cerebral palsy,early detection,early diagnosis
Energy Efficient Transprecision Techniques for Linear Solver (Entrans)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2020-05-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

All computations that use floating-point arithmetic are built on the fundamental assumption that the computation is meaningful when employing only a limited precision. The required precision typically varies throughout the computation and depends on the actual represented values. Many computations use too many bits of precision, which reduces performance and increases energy consumption. The Entrans project aims to utilize the optimal precision during a computation without loss of accuracy, which will result in higher execution speed and lower energy consumption. This idea, dubbed transprecision computing, requires novel results in numerical analysis and runtime decision making to adapt the precision of a computation on the fly. The Fellow, JunKyu Lee, is an expert in numerical analysis and will collaborate with the research group of Dr Hans Vandierendonck at Queen’s University Belfast, who are experts in high-performance and parallel computing. The Fellow will collaborate with experts in runtime systems software and with experts in computer architecture. This unique collaboration and combination of skill sets is crucial to embed dynamic, runtime behavior in numerical algorithms. This ambitious research project, in conjunction with formal training and bespoke mentoring will enhance the Fellow’s academic profile, research experience, and breadth of skill set in numerical analysis and high-performance computing. Providing fundamental insights in the runtime variation of precision requirements of numerical algorithms will improve their execution speed and energy-efficiency, but will also lay the foundation for the development of novel algorithms.

Keywords: high performance computing,transprecision,linear system solvers,energy saving,dynamic precision,mixed precision,speedup
Far Infrared Radiation Smart Fabric Heating Element for GreenHouses (AgrowFab)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Israel
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-05-01
End date: 2018-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

With AgrowFab, we aim to commercialize a new generation of smart heating fabric elements for greenhouses, constituting an innovation to the main challenges currently faced by the industry. Air convection heating systems, hot water pipes and lately radiative heating solutions are the main technologies used for greenhouse heating. However, they have specific drawbacks, namely energy waste (the system heats the entire greenhouse and not only the crops), increased pest infestation and collateral high pesticide use (as a result of the unnecessarily extensive heating) and low design and mechanical flexibility (heating surface is usually limited to tubes/pipes round shape). Our consortium formed by San Hitech, with 20 years’ involvement in engineering and project management and ThermoSiv, an innovative SME specialized in smart heating solutions to develop AgrowFab, using a highly cost-effective and environmentally-friendly heating fabric comprising nylon fibers coated with a proprietary non-metal carbon compound making them electrically conductive. Heat generated by an electric current flowing through these fibers is directly radiated to the crops as Far Infrared Radiation (FIR), creating a micro-climate around them. Our solution has unlimited design and mechanical flexibility and it also offers the possibility of soil sterilization, decreasing the need of pesticides. Its real-time response to crop needs can increase crop production by up to 35% and decrease energy consumption by at least 40%. AgrowFab can be powered using renewable energy sources such as solar panels or wind turbines and combines the aforementioned advantages with an estimated revenue increase of greenhouse businesses by up to 30%.Through this project, we aim to boost the competitiveness of both companies, reaching cumulative revenues of €55.31 million after 5 years of commercialization, creating 100 new job positions. With a total Phase 2 investment of €1.6 million, this would imply a ROI of 4.48.

Keywords: smart heating,greenhouses,retaliers,crops,pest infectation,nylon fibers,far infrared radiaction,micro climate,energy saving,crop production increase