Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Maximizing the impact of innovative energy approaches in the EU islands (INSULAE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: A single, smart European electricity grid
Action type: Innovation actions
Countries involved: Germany,Italy,Spain,Germany,Spain,Spain,Cyprus,Croatia,Croatia,Greece,Greece,Greece,Greece,Belgium,France,France,Bonaire, Sint Eustatius and Saba,Netherlands,Portugal,Denmark,Denmark,Denmark,United Kingdom,Portugal,Portugal
Call: Decarbonising energy systems of geographical Islands (H2020-LC-SC3-2018-ES-SCC, 2018)
Start date: 2019-04-01
End date: 2023-11-30
Duration (months): 56.0
Total project cost (EUR): 12073708.49
EU funding (EUR): 9999304.88
Participants: 33
Project status: SIGNED

The aim of INSULAE is to foster the deployment of innovative solutions for the EU islands decarbonization by developing and demonstrating at three Lighthouse Islands (located in Croatia, in Denmark and in Portugal) a set of interventions linked to seven replicable use cases, whose results will validate an Investment Planning Tool that will be then demonstrated at four Follower Islands (located in Spain, in Germany, in The Netherlands Antilles and in Greece) for the development of four associated Action Plans. The chosen islands are complementary in many aspects: location, size, connection with the mainland, economic development, renewable share and carbon intensity. INSULAE contributes to the Clean Energy for EU Islands Initiative by providing an Investment Planning Tool (IPT) able to create Actions Plans for the islands to generate their own sustainable, low-cost energy. The interventions will prove the ability of the use cases to develop RES-based systems 40-70% cheaper than diesel generation, thus, enabling an average reduction of the fossil fuel consumption of 11% after a large deployment of the use cases in the INSULAE islands. The INSULAE IPT will support the decision maker on the selection and design of cost effective Action Plans looking for the island decarbonization. It will be mainly composed by two modules: the Island modeling assistant and the Scenarisation module. The project team is carefully balanced along all the value chain counting with five public authorities, six energy and water utilities, four technology providers, two energy software developers, six RTOs, one environment NGO, one business models expert, one engineering company and one entity for social aspects and replication. The legal and regulatory framework of 57% of the total population living in EU islands will be directly considered within the project.

Keywords: energy storage,investment planning tool,action plans,electric mobility,bioeconomy,smart control,big data,local energy communities,water network,power electronics,desalination,dc grid
Multiscale Mechanics of Bone Fragility in Type-2 Diabetes (MULT2D)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Ireland
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-02-01
End date: 2024-07-31
Duration (months): 66.0
Total project cost (EUR): 1499659.0
EU funding (EUR): 1499659.0
Participants: 1
Project status: SIGNED

Type-2 (T2) Diabetes is associated with a 3-fold increase in bone fracture risk, despite the fact that bone volume is not reduced. This implies that T2 diabetes impairs bone quality, whereby the intrinsic material properties of the bone matrix are altered. However, current diagnostic techniques are unable to predict fracture probability in T2 diabetes as they are based on measures of bone quantity. While it is believed that non-enzymatic cross-linking of organic proteins (also known as AGE accumulation) in the bone matrix is responsible for bone fragility in T2 diabetes, there is a distinct lack of understanding how altered protein configurations impair whole-bone biomechanics. In this project, the applicant will embark on frontier research that will develop a state-of-the-art multiscale computational framework that couples behaviour from the molecular to whole-bone level, providing a basis to interrogate and elucidate the physical mechanisms that are responsible for diabetic bone fragility. A multiscale experimental framework will, for the first time, establish relationships between AGE crosslink-density and whole-bone fragility in animal and human T2 diabetic bone tissue. Together, this data will inform a probabilistic mutli-level model of hip fracture, which will be used to quantitatively evaluate the relationship between hip fracture probability, bone quantity and bone quality. The research programme will also establish a novel strategy for clinical fracture risk assessment that employs existing protocols to measure bone quantity, in combination with a surrogate measure of bone quality. The surrogate measure of bone quality proposed is a systemic measure of AGE content, which is clinically-obtainable through a blood sample and therefore widely-applicable. Overall, the project will provide a ground-breaking advance in our understanding of bone fragility, with remarkable potential to innovate novel solutions for clinical assessment of T2 diabetic bone disease.

Keywords: multiscale modelling,bone mechanics,bone fragility
The Algal Microbiome: Friends and Foes (ALFF)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany,Germany,Germany,Ireland,Hong Kong,Türkiye,Belgium,Belgium,Belgium,France,France,Czechia,Czechia,Netherlands,United Kingdom,Portugal,Canada,Portugal,United Kingdom
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 3710595.24
EU funding (EUR): 3710595.24
Participants: 28
Project status: CLOSED

Algal aquaculture is developing exponentially worldwide, with multiple applications in the food, chemical and pharmaceutical industries. Current research in algal biotechnology mostly focuses on metabolite discovery, aquaculture yield improvement and engineering bottlenecks. However, agronomical experience shows that controlling the interaction of land crops with mutualistic or pathogenic microbes is most critical to successful production. Likewise, controlling the microbial flora associated with algae (the 'algal microbiome') is emerging as the biggest biological challenge for their increased usage. Bacteria can control the morphogenesis of algae, while others are indispensable to algal survival. Pathogens are causing devastating diseases, the impact of which worsens with the intensification of aquaculture practices. Thus, the overarching aim of ALFF is to train 15 ESRs (researchers and technologists) within a multinational consortium, whilst bringing a scientific step-change in our understanding of these interactions, leading to the development of superior mass algal cultivation and biocontrol strategies. ALFF tackles: 1) the identification, taxonomy and utilisation of naturally-occurring algal symbionts and pathogens; 2) inter- and intra-species signalling and chemical ecology in aquaculture, natural environment and simplified systems (i.e. axenic cultures +/- symbionts); 3) and harnesses state of the art genomics, molecular, and biochemical techniques to characterise these interactions. A highly interdisciplinary team underpins an ambitious theoretical, field, hands-on training and research program. With the support of high profile institutions, ALFF foresees an exceptionally broad range of dissemination and outreach initiatives to help policy makers and the general public better understand the opportunities and issues relating to the sustainable use of our aquatic freshwater and marine resources, within and beyond the EU.

Keywords: algal biotechnology,algal aquaculture,pathogen,symbiont,endophyte,biofilm,macroalga,seaweed,microalga
Structure Theorems for Modern Aspects of Geometric Measure Theory (STMAGMT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2020-10-01
End date: 2025-09-30
Duration (months): 60.0
Total project cost (EUR): 1421562.0
EU funding (EUR): 1421562.0
Participants: 1
Project status: SIGNED

The aim of this research proposal is to develop the necessary theory of three areas of Geometric Measure Theory in order to solve several fundamental open questions. The origins of these questions can be found in recent advancements in various areas of modern analysis, such as the calculus of variations, harmonic analysis and geometric function theory, and differential geometry. The project will use and expand upon techniques recently pioneered by the PI. These techniques demonstrated the viability of geometric measure theory in arbitrary metric spaces. One focus of this project will be to continue with the natural progression of this research. The other focus will be to developing these techniques in order to solve seemingly unrelated problems in new areas of analysis. These methods have been successfully used to solve many well known questions, but it is clear that their full potential has yet to be realised. The main areas of interest are: (A): Fundamental questions regarding geometric measure theory in metric spaces. A central point of interest will be generalising classical characterisations of rectifiability to non-Euclidean settings. (B): Characterisations of quantitative rectifiability. The main goal is to prove a quantitative analogue to the Besicovitch--Federer projection theorem conjectured by David and Semmes. (C): The structure of currents. In particular, the project will follow a path towards solving the flat chain conjecture of Ambrosio--Kirchheim. Each of these areas concerns difficult yet important problems. As with other fundamental results of GMT, it is expected that these techniques will find applications far beyond their original purpose.

Keywords: geometric measure theory,rectifiability,analysis on metric spaces,quantitative rectifiability,currents
Patent pending gearboxA patent pending gearbox for ships that decrease fuel consumption with 25% (appr 500 ton fuel and 1500 ton carbon dioxide per ship and year) (OXM)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Sweden
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2015, 2015)
Start date: 2016-03-01
End date: 2016-08-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Optixmarine offers a patent pending gearbox for ships with shaft generators and the result is a saving of approximately 500 ton (25%) fuel and 1 500 ton carbon dioxide emission per ship and year. Our product, the gearbox "Optixdrive", is today designed and constructed in order to be installation at our pilot customer AB Veritas Tankers vessels “Astoria” in Q1 2016. We have very strong customer interest and after launching the product at the fair Donsö Shipping Meet in September 2015, we are contacted by several new customers every month. Our customers have also stated that there are no attractive alternatives to our product. Worldwide we estimate a total market of more than 7 000 ships with generators, worth 2,1 billion euros. The product is priced to 300 000 euros, which gives customers less than two years in return of investment and this has been confirmed attractive by them. We have eliminated the technical risk with our gearbox through involving leading technical experts and manufacturers, that through calculations and simulations have come to the conclusion that they see low risk with getting our product up and running. On the island of Donsö outside Gothenburg, there are shipping companies that together have 60 ships with shaft generators and therefore potential customers for Optixdrive. Only them together would mean an annual saving of as much as 30 000 ton of fuel and 150 000 ton of carbon dioxide. Imagine the worldwide fleet of ships with shaft generators using Optixdrive, that would mean a saving of 3,5 million ton of fuel and 10,5 million ton of carbon dioxide every year. The team behind Optixmarine believe that transport by sea has a environmental sustainable future and our company has a promising potential to drastically reduce the environmental impact by the shipping industry worldwide.

Keywords: fuel efficiency,decarbonize,lower emissions,shipping,green innovation,powertrain
Seeing things you don't see: Unifying the philosophy, psychology and neuroscience of multimodal mental imagery (STYDS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Belgium
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-09-01
End date: 2024-08-31
Duration (months): 84.0
Total project cost (EUR): 1966530.0
EU funding (EUR): 1966530.0
Participants: 1
Project status: SIGNED

When I am looking at my coffee machine that makes funny noises, this is an instance of multisensory perception – I perceive this event by means of both vision and audition. But very often we only receive sensory stimulation from a multisensory event by means of one sense modality. If I hear the noisy coffee machine in the next room (without seeing it), then how do I represent the visual aspects of this multisensory event? The aim of this research project is to bring together empirical findings about multimodal perception and empirical findings about (visual, auditory, tactile) mental imagery and argue that on occasions like the one described in the last paragraph, we have multimodal mental imagery: perceptual processing in one sense modality (here: vision) that is triggered by sensory stimulation in another sense modality (here: audition). Multimodal mental imagery is rife. The vast majority of what we perceive are multisensory events: events that can be perceived in more than one sense modality – like the noisy coffee machine. And most of the time we are only acquainted with these multisensory events via a subset of the sense modalities involved – all the other aspects of these events are represented by means of multisensory mental imagery. This means that multisensory mental imagery is a crucial element of almost all instances of everyday perception, which has wider implications to philosophy of perception and beyond, to epistemological questions about whether we can trust our senses. Focusing on multimodal mental imagery can help us to understand a number of puzzling perceptual phenomena, like sensory substitution and synaesthesia. Further, manipulating mental imagery has recently become an important clinical procedure in various branches of psychiatry as well as in counteracting implicit bias – using multimodal mental imagery rather than voluntarily and consciously conjured up mental imagery can lead to real progress in these experimental paradigms.

Keywords: mental imagery,perception,multimodality
Molecular Mechanical Adhesives (MMA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Switzerland
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-04-01
End date: 2023-03-31
Duration (months): 72.0
Total project cost (EUR): 1466916.0
EU funding (EUR): 1466916.0
Participants: 1
Project status: SIGNED

Protein-based hydrogels are commonly used as adhesives and sealants in surgical settings. Fibrin gels, for example, are biocompatible, however their use is hampered by poor mechanical properties. Previous attempts to improve fibrin gel mechanics relied on interpenetrating networks in combination with PEO, collagen and other polymers, however, only modest improvements were observed. The important challenge lies in understanding how molecular design principles can influence gel mechanics on the macroscale. The goal of this research is to develop mechanically tunable protein hydrogels. Upon mixture of two liquid components, the systems I propose would spontaneously form a gel matrix consisting of oligomerized proteins that mimic the extracellular matrix and possess controllable mechanical responses. By understanding protein nanomechanics at the single-molecule level, and designing modes of energy dissipation into hydrogel networks, my project will have an impact by bridging the knowledge gap between single-molecule and macroscopic mechanical responses. My approach is ground-breaking because I am leveraging the discoveries I made on a family of super-stable receptor-ligand proteins (Cohesins & Dockerin (Coh-Doc)). These reversible receptor-ligands can be broken and reformed thousands of times, yet still maintain high stability (1/2 covalent bond strength). After having pioneered the application of these mechano-stable domains as molecular handles in single-molecule experiments, I propose the following frontier research: A) I will use molecular engineering of Coh-Doc complexes to test the hypothesis that mechanical properties of bulk materials can be rationally designed based on single-molecule mechanical behavior of receptor-ligands. B) I will adapt the system to seamlessly merge with the native fibrin clotting pathway, providing a self-healing mechano-stable fibrin-based gel that could be applied as a liquid or spray and strongly adhere to cells and tissues.

Keywords: single molecule biophysics
Book History and Translation History: Copyright, Wages, Censorship, and the (Proto-)Professionalisation of Translators in Nineteenth-Century Britain and Ireland (TRANSACT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-10-01
End date: 2020-11-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Hosted at the School of Advanced Study (SAS), University of London’s prestigious research-intensive institution that brings together nine research institutes, the Fellowship will address and exploit the synergies between book history and translation history by combining the researcher’s perspective in the area of translation studies with the expertise and resources available at SAS in the field of book history. Based at the Institute of English Studies, which specializes in the history of the book, manuscript and print studies, the researcher will be able to draw on the expertise of her supervisor, Dr Andrew Nash, Reader in Book History, Deputy Director of IES, and Director of the London Rare Books School. The project will generate new knowledge about the production of English-language translations in the nineteenth century by investigating the relations between translators and their publishers and the “proto-professionalisation” of translators in Ireland and Britain, in a century marked by large-scale changes in print culture and by the increasing professionalisation of authors. The research will draw on a number of key publishers’ archival records, principally at the British Library and University of Reading. Addressing a lacuna in the history of the book, the project will provide much-needed insights into the working conditions and social circumstances of translators, both male and female, paying special attention to copyright, censorship and translators’ remuneration. Supported by an international and multidisciplinary team of academic specialists, including the Institute of Modern Languages Research, the Fellow will expand her research and professional network through dissemination activities and engagement with academic, professional and wider publics. Formal training in book history, quantitative methods, digital media, project management and curatorial work will enhance her academic and professional skills to significantly improve her career perspective.

Keywords: book history,translation history,translators,women translators,publishers,nineteenth century,britain,ireland,authorship,copyright,censorship
From Neurons to Robots: Non-Invasive, General-Purpose Interfacing With Human Spinal Motor Neurons (INTERSPINE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-07-01
End date: 2018-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

INTERSPINE (“From Neurons to Robots: Non-Invasive, General-Purpose Interfacing With Human Spinal Motor Neurons”) aims at exploiting the methodologies developed during the ERC Advanced grant DEMOVE (“Decoding the Neural Code of Human Movements for a New Generation of Man-machine Interfaces”). During DEMOVE, novel bioelectrodes and computational methods have been developed to enrich our fundamental understanding of the mechanisms underlying the generation of human movements, from the cellular level to the function. These methods also contributed to the development of new schemes for controlling bionic limbs to substitute missing ones in amputees. INTERSPINE will translate these methods, and specifically those based on non-implanted electrodes, to develop a more robust general system that extracts neural information (at the individual cell level) from the human spinal cord and transforms it into extremely accurate commands to external devices, such as prosthesis, general purpose and teleoperated robots, and computer interfaces. This will be the only non-invasive man-machine interface based on direct neural activity (spiking of neural cells). The ERC Grant DEMOVE demonstrated in laboratory conditions that this approach is feasible and allows the identification of the exact timing of each activation of neural cells in the spinal cord, known as motor neurons. INTERSPINE will extend this approach through wearable devices and real-time processing, as well as with a robust association between the identified neural activity and external commands to devices, with the aim of revolutionizing everyday man-machine interfacing. The direct decoding of neural activity will provide unprecedented accuracy and robustness with respect to other non-invasive approaches. Keywords: man-machine interfacing; motor neurons; electromyography (EMG); prosthesis; movement; spinal cord; muscles; motor control.

Keywords: man machine interfacing,motor neurons,electromyography emg,prosthesis,movement,spinal cord,muscles,motor control