Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Specialised international student recruitment management platform (DreamApply EU)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Estonia
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

If Europe wants to compete with the U.S and with the rest of the world, it needs innovative ICT solutions, such as DreamApply EU that support universities to easily find national and international students and vice versa, and fosters international student mobility towards the Old Continent. The feasibility assessment will focus on following technical and business objectives during its 6 months, to develop a robust plan for Phase 2: • Prepare software development plan to finalize DreamApply EU that meets Functional Requirements; • Scout and secure at least 15-20 pilot customers i.e. European higher education institutions (such as Tallinn university of technology, Vilnius Gediminius Technical University, Poznan University of Economics, Kaunas University of Technology), to achieve a viable size of the ecosystem, so that the platform can be setup, implemented and validated over a period of 12 months. DreamGroup will scout and contact decision takers/ influencers from academic and governmental areas and from EU Institutions that can positively influence to secure pilot customers and achieve the expected outcomes of the project. The Estonian Ministry of Education provided a Letter of Support for this project.
New Generation Therapeutic vaccine for the Treatment of HPV infections and Cervical Dysplasia (CerviVax)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Biotechnology
Action type: SME instrument
Countries involved: Spain
Call: SME boosting biotechnology-based industrial processes driving competitiveness and sustainability (H2020-SMEINST-1-2015, 2015)
Start date: 2015-09-01
End date: 2016-02-29
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

VLPbio (www.vlpbio.com) is a biotechnological company applying immunotherapeutic solutionsto fight and prevent human and animal diseases addressing unmet clinical needs in the main pharmaceutical markets. Our technology is based on patented and proprietary Ch-VLP platform (Chimeric Virus like Particles) derived from the Infectious Bursal Disease Virus (IBDV). Virus-like particles are empty and not infectious viral particles capable of incorporating antigens involved in different pathologies in order to potentiate and direct the humoral or cellular immune response. The potential of the platform to induce both kind of responses has been validated through immunogenic studies and in vivo proofs of concept. Our business model is to develop innovative vaccines based on our proprietary technological platform up to phase I, where the product will be licensed to a larger biotech or pharmaceutical company Our main product is Cervivax https://www.dropbox.com/s/p2s06bqm9toai3n/VLPbio.mov?dl=0, an immunotherapeutic vaccine focused on the treatment of cervical dysplasia and infections caused by HPV-16 (Human Papilloma Virus), which is responsible for most of the cases of cervical lesions detected all over the world. Although, there are prophylactic approaches to prevent viral infection, currently do not exist commercial therapeutic solutions to treat infections or lesions caused by the infection, other than surgery combined by chemotherapy. We position our product to cover this unmet need. We have an in vivo efficacy proof of concept of the product with excellent results, overpassing those of other therapies under development in terms of efficacy in absence of any adyuvant (1). The overall aim of the project that we are submitting is bring Cervivax from the current status up to clinical-phase I, where we are aiming to license it to a large biotech or pharma company. Currently we have two preliminary agreements with 2 leading pharma companies, which are in due diligence phase

Keywords: cervical cancer,immunotherapy,nanotechnology,nanomedicine,bioprocess development,recombinant protein production,good manufacturing practises,virus like particles,therapeutic,vaccine
Planning and operational tools for optimising energy flows and synergies between energy networks (PLANET)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: A single, smart European electricity grid
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Italy,Italy,Germany,Finland,Greece,Belgium,Greece,France,United Kingdom
Call: Tools and technologies for coordination and integration of the European energy system (H2020-LCE-2017-SGS, 2017)
Start date: 2017-11-01
End date: 2021-01-31
Duration (months): 39.0
Total project cost (EUR): 3999695.0
EU funding (EUR): 3999695.0
Participants: 17
Project status: CLOSED

The future electricity generation mix evolution, EU projects 97% generation from variable RES by 2050, will render current solutions for grid balancing and stability insufficient. Intermittent generation will require extensive electricity demand flexibility - beyond conventional solutions - to alleviate the unpredictable grid stresses in high VRES times. This flexibility cannot only come from electricity end-uses, the volatility and variability of RES generation is too high. Energy system decarbonisation will necessitate the use of novel conversion and storage in alternative energy carriers and their networks to achieve the avoidance of RES generation curtailment. The PLANET aim is to design and develop a holistic Decision Support System for grid operational planning and management in order to explore, identify, evaluate and quantitatively assess optimal strategies to deploy, integrate and operate conversion/storage systems on the distribution grid of several energy carriers within boundary constraints of real deployments outlined in the future energy system scenarios. Such tools are crucial for policy makers and network operators who need support in decision making process. The simulation of the integration between electricity, gas and heat networks models, together with conversion/storage technologies models for power-to-gas, power-to-heat and virtual thermal energy storage, will help to understand and quantify how these conversions can affect network stability, reliability and responsiveness as well as to optimize these metrics across networks. The PLANET tools will be demonstrated and validated using information from the actual premises and customers of two distribution network operators in Italy and France. They manage electricity, natural gas and district heating networks, hence they provide a solid testbed corresponding to real-world solution deployments to evaluate the actual benefits of PLANET solutions.

Keywords: synergies between networks,electricity,district heating,natural gas,power to gas,power to heat,virtual energy storage,network planning tools,grid operation ict tools
The next-generation digital inspection platform for fully remote supply chain monitoring (CyRaCo Box)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-12-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The global Testing, Inspection and Certification (TIC) market is expected to reach €250 billion by 2024, driven by international trade, tightening regulations and outsourcing. This market is also changing radically and will experience a complete technological revolution, as traditional TIC services are now in decline in favor of digitalized alternatives. This is particularly relevant for the manufacturing vertical, where manufacturers and retailers still heavily rely on third party quality inspectors to monitor the supply chain. This process is expensive, complex and unreliable, since real-time inspections are not feasible on remote locations. Additionally, current digital alternatives are not fully automated and lack the tools to guarantee a full inspection. Existing partial solutions only provide highly specific tools and do not offer cross-sector factory inspections. Our team of highly experienced experts in the TIC field is developing the CyRaCo Box, a unique and patent-pending tool that provides a reliable, efficient and real-time remote factory inspections. It combines 3D Modelling, Augmented Reality, Cloud technology, analytics and smart sensors to offer completely automated and fail-safe factory inspections. As a result of the improved efficiency and automation, it also reduces traditional inspection costs by 90%. The CyRaCo Box wil democratize supply chain monitoring, promote supplier accountability and pave the way towards real ethical sourcing. Additionally, it will also facilitate international trade for European SMEs, which do not have the necessary resources to develop expensive in-house inspection infrastructure. The unique features of the CyRaCo Box will allow us to grow exponentially and disrupt the inspection market, with a highly scalable and flexible subscription-based business model. By 2024, we will already perform almost a thousand factory inspections, generating over €16 million in revenues and resulting in a ROI of 7.75.

Keywords: factory inspection,remote inspection,testing,inspection and certification,supply chain monitoring,ethical sourcing
Function and Organization of Feedback Connections (FOFC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-09-01
End date: 2022-01-04
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

Less than 10% of synapses in sensory areas of cerebral cortex are from feedforward input; the rest stem from lateral and feedback connections. Much experimental and theoretical research into sensory processing, however, focuses on the feedforward pathway despite the significant impact feedback connections have on activity. What role do feedback connections play, and how do they carry them out? This project combines computational modeling with in vivo imaging to explore the function and organization of feedback connections in the mouse visual system. Specifically, it proposes training neural network models with feedback connections on different challenging visual tasks, each inspired by a hypothesized role of feedback (such as prediction or localization). Once these models are trained, their response to images can be compared to experimental data collected from multiple visual areas. These models also provide an ideal experimental setting wherein the anatomy of the learned feedback connections can be fully characterized. These characterizations can inform hypotheses about what feedback features should be present in the biology. To explore if these features are present, in vivo imaging will be used to characterize the information carried by different feedback pathways in the mouse visual system. The impact of feedback on neurons in V1 will also be determined by comparing activity under normal circumstances to when these feedback pathways are silenced. In summary, this work will use modeling to relate properties of feedback connections to their function and test for these properties experimentally. It will also develop an approach that can be applied to many neural pathways.
Research Infrastructure on Religious Studies (ReIReS)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Integrating activities and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Italy,Italy,Belgium,Bulgaria,Poland,Belgium,France,Netherlands,Netherlands
Call: Integrating Activities for Starting Communities (H2020-INFRAIA-2017-1-two-stage, 2017)
Start date: 2018-02-01
End date: 2021-07-31
Duration (months): 42.0
Total project cost (EUR): 3084351.25
EU funding (EUR): 3083936.25
Participants: 12
Project status: CLOSED

ReIReS is a starting community whose aim is to create a unique and groundbreaking research infrastructure (RI) on religious studies within the European Research Area. It joints the major European research institutions working in the domain (universities, libraries, archives, academies, research institutions, and museums) to improve the access of scholars from all over the world to the data, information and sources concerning the study of the historical and cultural influence of the plural religious heritage in the European history. Furthermore, it joints research activities of the partners, integrating complementary scientific skills and capabilities, and it organizes networking activities for fostering a culture of co-operation between national research facilities, scientific communities, and other stakeholders including policy makers. ReIReS creates a synergy between the partners, offering a transnational and virtual access to the most significant tools and sources in the field of religious studies. This grants to the research communities the use of the major tools joint within a comprehensive infrastructure and gives to the EU a leading role in a domain, which is becoming more and more crucial for the understanding of inter-cultural dynamics and facing conflicts of our time. Dealing with the need for an appropriate comprehension of a complex and multicultural society, ReIReS consortium works towards the improvement of the integrated services of the partners. It aims to establish a distributed RI with a sustainable plan of activities, including offering access to a wide range of high-level data and tools for advancing knowledge and innovation in the understanding of inter-religious society.

Keywords: historical religious studies,distributed research infrastructure
TRA VISIONS 2016 (TRA VISIONS 2016)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Coordination and support actions
Countries involved: Germany,Italy,Germany,Netherlands,United Kingdom,United Kingdom
Call: Innovation awards for students and researchers in the context of the Transport Research Arena conference - TRA 2016 (H2020-MG-2014_SingleStage_A, 2014)
Start date: 2014-12-01
End date: 2016-11-30
Duration (months): 24.0
Total project cost (EUR): 499937.5
EU funding (EUR): 499937.5
Participants: 6
Project status: CLOSED

The concept of this project is to organise two competitions for transport research awards to be announced at the TRA conference in 2016 - A student competition with the goal of stimulating the interest among young researchers/students in the field of sustainable surface transport. - A competition for senior researchers in the field of innovative surface transport concepts based on results only from EU-funded projects.

Keywords: student competition,researcher competition
A unique, interferon-based veterinary therapy to minimize antimicrobial overuse in cattle and tackle the societal global problem of antimicrobial resistance (INFarm)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-05-01
End date: 2019-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The rise of antimicrobial resistance (AMR) is a major threat to global public health as it will cause 10 million deaths per year by 2050. The rise in AMR is largely driven by the abundant mis- and overuse of antimicrobial drugs in humans and animals. As such, there is a strong demand to reduce the use of antimicrobials in animals, putting cattle farmers under enormous pressure to change their current way of working. However, the lack of appropriate alternatives is hindering them to renounce from (over)using antimicrobials as their production output and income are at risk. At FarmPharma, we are on the mission to provide effective, safe and affordable solutions to keep livestock animals healthy and well. To do so, we are developing InterferOx, an interferon-based, immune-stimulating, anti-infective therapy for cattle with the unique ability to treat AND prevent viral AND bacterial infections. InterferOx can thus minimize the use of antimicrobials in cattle by providing farmers an effective and sustainable alternative, thereby providing a solution for the rise in AMR. The global market volume is 1.5 billion cattle, with our total addressable markets of Europe and US accounting for 121 and 94 million, respectively. With InterferOx, we respond to the trends and needs of our €1.7 billion target market: the cattle antimicrobials market. We aim to commercialize InterferOx via a licensing deal with a pharmaceutical company after completing clinical validation. In return, we will receive upfront, milestone and royalty payments with an estimated value of €77.8 million within the next 7 years. To maximize our chance of realizing this promising future, we will perform a feasibility study, focusing on market analysis, commercialization strategy, IP strategy and value chain, to deliver a consolidated business plan. This will give us a clear understanding of the commercial potential of InterferOx, strengthen our current infrastructure, and define our optimal business strategy.

Keywords: veterinary medicine,antimicrobial resistance,interferons,cattle farming,viral infections,bacterial infections,therapeutic,prophylactic,drug development
Injected Moulded barriers for cost effective food packaging (CLAYMBAR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Italy,Italy
Call: Accelerating the uptake of nanotechnologies, advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2014, 2014)
Start date: 2015-05-01
End date: 2015-10-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

Our company, MPG Manifattura Plastica S.p.A., is a well-established Italian company (€15M turnover), specialised in thermoformed and injected packaging for food industry (e.g. ice-cream, powedered food, cheese). With more than 30 years’ experience, our philosophy is to sell not only a product but a complete service to our customers (Heinz, Nestlé, Unilever). For this purpose, our R&D team keeps developing new products to better satisfy the client’s requirements. This has led us to the development of CLAYMBAR, a new nanoclay-polymer based container, produced by injection moulding, designed to address our customers’ needs in terms of price, shelf stability and life. By offering our customers the needed packaging solutions to increase their competitivity and accelerate their growth -, we will broaden our product portfolio of thermoformed and injected moulded rigid plastics (+49% of turnover after 5 years). Our partner, Color System S.P.A., is one of the leading companies in the production of masterbatches. Our partnership with CS has been develop through several industrial projects as a masterbatches provider and they will consolidate their commercial relationship with us through the CLAYMBAR project being the main partner as masterbatch supplier, multiplying by 3 their revenues by 2022.

Keywords: plastic food packaging,barrier,nanoclay,injection moulding,masterbatch
Imaging with Photon Counting: Reduced costs, increased dynamic range (PhotonCount)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC Proof of Concept Grant (ERC-2014-PoC, 2014)
Start date: 2015-04-01
End date: 2016-03-31
Duration (months): 12.0
Total project cost (EUR): 147500.0
EU funding (EUR): 147500.0
Participants: 1
Project status: CLOSED

Optical methods and fluorescent proteins to probe and manipulate cellular and subcellular processes have proven to be a major driving force behind many recent breakthroughs in biology and medicine. Recent developments in photonics have led to increased spatial and temporal resolution and now allow the study of single identified synaptic contacts between neurons as well as large-scale neuronal networks. Brain tissue strongly scatters light. Thereby, the amount of light emitted by fluorescent probes in small structures inside neuronal tissue that reaches the microscope objective is small. Fluorescence imaging in living tissue, as I use in my ERC-funded research program, is therefore limited by low signal-to-noise levels. One approach in increasing the level of such weak fluorescence is to increase the excitation power, but this has the undesirable effect of bleaching the fluorescence faster and damaging the cell. Another approach is to optimize the fluorescence collection by using high-end microscope objectives in the 20,000 eur range with improved light transmission, high numerical aperture and low magnification that can collect fluorescence more efficiently. Although these objectives brought a significant improvement to imaging applications, physical limitations in their design cannot offer anymore a similar qualitative improvement as previously. Since there is a great need to further improve biological imaging, the present proof of concept application aims to achieve this by developing advanced, but low-cost, electronics for the optical detection of weak fluorescence signals through Photon Counting, and bring this technology to the market.

Keywords: optical imaging,fluorescence,signal detection,microscopy