Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Bentonite mechanical evolution (Beacon)

Framework: Horizon 2020 — Euratom
Programme: Nuclear fission and radiation protection
Theme: Radioactive waste management
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Germany,Germany,Spain,Sweden,Switzerland,Belgium,Finland,Finland,Lithuania,Switzerland,Finland,Sweden,Sweden,France,France,Czechia,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Addressing key priority R&I issues for the first-of-the-kind geological repositories (NFRP-2016-2017-1, 2016)
Start date: 2017-06-01
End date: 2022-05-31
Duration (months): 60.0
Total project cost (EUR): 4051777.5
EU funding (EUR): 3804205.76
Participants: 26
Project status: CLOSED

The overall objective of the project is to develop and test the tools necessary for the assessment of the hydro-mechanical evolution of an installed bentonite barrier and its resulting performance. This will be achieved by cooperation between design and engineering, science and performance assessment. The evolution from an installed engineered system to a fully functioning barrier will be assessed. One of the challenges is to take into account initial heterogeneities introduced in the system by conception with a combination of block and pellets or due to the size of the bentonite component (several 100 m3). It will require a more detailed understanding of material properties, of the fundamental processes that lead to homogenisation, of the role of scale effects and improved capabilities for numerical modelling. The goal is to verify the performance of current designs for buffers, backfills, seals and plugs. The overall driver for the project is the assessment cases that will be defined at the onset of the project (WP1). The quantitative models currently available are not fully able to represent all the complexities of the evolution of an installed bentonite. A substantial effort is needed to improve both the conceptual approaches and the numerical solutions in the current models (WP3). The updated/newly developed models need to be tested and verified using available data (WP5). There are some areas where fundamental data and the understanding of materials are incomplete. An efficient experimental programme will support model development and testing (WP4). There is already a large database from experiments performed within EC projects and national programmes, both laboratory and Underground Research Laboratory (URL) experiments. Many of the tests have been performed with other purposes in mind, but the results can be used in the Beacon project. The objective of WP2 is to collect the relevant information and process it to a level where it can be used in this project

Keywords: bentonite
ON-FIELD INNOVATIVE SYSTEM TO DETECT VERY LOW CONCENTRATIONS OF AFLATOXINS IN MILK (SAFEMILK)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: SME instrument
Countries involved: Italy
Call: Stimulating the innovation potential of SMEs for sustainable and competitive agriculture, forestry, agri-food and bio-based sectors (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-02-01
End date: 2017-07-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

IDP is an Italian SME focused on industrial automation and measurements. IDP owns a unique and proprietary Variable Optical Path Spectroscopy technology, VOPS, that is currently used in in-line equipment to monitor the concentration of chemicals in processing fluids. IDP is exploring new ways how to adapt this technology for the Food Industry, specifically for detecting small concentrations of aflatoxins in milk batches before transportation and processing. In this framework the business objective of SAFEMILK project is to further develop the VOPS technology and integrate it with a spectral engine and chemiometric SW to commercialise by 2020 an high-accuracy, fast, low-cost, non-destructive system to measure in field the B1, M1-aflatoxins content in milk to very low concentrations as set by regulations. The uniqueness of SAFEMILK will disrupt the Food Safety Market bringing new benefits to the industry and to the consumer. The early detection and the possibility to easily perform tests every day on the milk to be delivered basically cancel the risks to expose human to the toxicity of aflatoxins along the value chain. IDP believes that SAFEMILK will raise the Company profitability and grow its workforce by tackling this huge business opportunity. IDP requires further financing through the SME Instrument to accelerate and fund the commercialisation of SAFEMILK in the milk and dairy industry at first and later with several other profitable areas of the food market.

Keywords: milk contamination,food safety market,spectroscopy technology,portable device
Nordic Angel Investment Program (NordicAIP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Estonia,Estonia,Norway,Finland,Denmark
Call: Startup Europe for Growth and Innovation Radar (H2020-ICT-2017-1, 2017)
Start date: 2018-01-01
End date: 2019-12-31
Duration (months): 24.0
Total project cost (EUR): 1583312.5
EU funding (EUR): 1469687.5
Participants: 7
Project status: CLOSED

The strategic objective of Nordic Investment Program (Nordic AIP) is to help European high-tech start-ups and innovative SMEs to grow and scale up at pan-European and global level. The strategic objective is supported by the following sub-objectives: - Stimulate European investments in digital sectors; - Create increased mutual understanding between investor communities and in particular ICT startups and scaleups. To achieve these objectives, Nordic AIP consortium will implement the following actions: - Raise awareness about opportunities for early stage investing in digital sectors; - Increase the knowledge and actual experience of ICT startups and investors on the investment process into early stage digital companies through the Angel Investment Program (AIP). - Significantly improve the efficiency of managing investment processes through the development of the Startup Includer technology. During 24 months, NordicAIP project will deliver the following outputs: - 200 000 stakeholders are informed about NordicAIP activities; - Technology platform Startup Includer developed for facilitating cross-border investment processes; - 16 Angel Investment Programs (AIPs) are organized in 4 countries; - 1000-1600 applications are received for the AIPs (50-100 in each); - Selection of 360 ICT startups and scaleups in total, 20 per AIP to enter the Programme; - 400 investors are involved in the AIP trainings, workshops and due diligence process of the AIPs (25 investors in each AIP) and make an actual investment of 10 000 EUR on average; - 20% of the investors are cross border from the Nordic region and beyond; - 16 innovative ICT startups and scaleups receive funding via the AIPs, further syndication activities are stimulated through the joint sessions in the AIP; - 4 million euros are invested into the ICT startups and scaleups in total (approximately 250 000 per AIP).

Keywords: nordic cooperation,cross border cooperation,angel investment program
Innovative Aluminium filler Wires for Aircraft Structures (IAWAS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Romania,Belgium,France,United Kingdom
Call: Development of innovative aluminium filler wire based manufacturing of aeronautic components and structures (H2020-CS2-CFP07-2017-02, 2017)
Start date: 2018-10-01
End date: 2022-10-31
Duration (months): 49.0
Total project cost (EUR): 498923.75
EU funding (EUR): 498923.75
Participants: 4
Project status: CLOSED

The project aims at: (1) developing new Al filler wires for WAAM and LBW of the new Al-Li alloys, (2) optimising the WAAM process and implementing suitable post-treatments, (3) characterising the microstructure, mechanical and corrosion properties of the optimised post-treated WAAM material, (4) manufacturing by WAAM two demonstrators of the targeted part and inspecting their quality. New Al wire compositions will be defined after a literature review of the different processes involved and WAAM and LBW tests on existing extrudable Al alloys. The new Al wires will be manufactured via casting and extrusion of bar-shaped semi-products that will be drawn. A parameter study will be performed for each of these processes. The new wires will be tested in the LBW and WAAM processes that will allow to select the most suitable new wire per process and to identify ways of improvement in their manufacturing route and composition. A 2nd loop of manufacturing and testing will be performed until achieving the best possible quality. In parallel, the WAAM process will be developed, optimised and completed with post-treatments. The development will be performed with the existing Al alloys until the production of the new wires. The optimised post-treated WAAM material issued from the final new wire will be characterised for analysing its microstructure and evaluating its mechanical and corrosion properties. Two demonstrators of the targeted part will be manufactured using the final new wire and the optimum WAAM conditions. A structural and geometry analysis will be performed prior to their manufacturing. Their quality will be inspected and a cost analysis will be done.

Keywords: wire drawing,aluminium alloys,additive manufacturing,laser beam welding,aircraft industry
Development of a Cavity Supported Lipid Membranes Biomimetic drug permeability models (CLIMB) (CLIMB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-01-01
End date: 2019-12-31
Duration (months): 24.0
Total project cost (EUR): 175866.0
EU funding (EUR): 175866.0
Participants: 1
Project status: CLOSED

Permeability Assay (PAMPA) have limited biorelavance and can often be poorly predictive of of drug permeation, particularly for charged species and for complex membranes such as the BBB and particularly of membrane toxicity which remain key issue leading to high attrition rate and low productivity in the pharmaceutical industry. The proposed fellowship programme aims to address these issues in a very novel way by developing lipid bilayers supported on cutting-edge Plasmonically-Directed Nano-Structured porous arrays. The substrates prepared via a range of fabrication methods, including 2-photon 3D-nanoprinting, will allow for investigation of drug-membrane interactions, and permeability through a unique and novel principle, whereby the arrival time of single or few weakly- or non-fluorescent molecules at plasmonic volume in the nano-/micro-cavity is monitored via enhanced spectroscopic technique. Angle dependent Raman microscopy will permit study independently of the drug-membrane interactions and plasmonic hot spot so both structural and permeation times can be meausered and these studies will be carried out in parallel with Elelctrochemcial impendence spectroscopy of membrane integrity. This approach will dramatically advance the state-of-the-art in membrane assay. In parallel it provide high quality research training to the MRSA fellow along with, supported by the host institution training programme a range of career promoting transferable skills acquired. Leading the fellow to a fully-independent academic position.

Keywords: spectroscopy,photophysics,biophysics,electrochemistry
Targeting genetic and epigenetic mechanisms in pediatric sarcomas. (PedSarc)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Germany
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-01-01
End date: 2024-12-31
Duration (months): 72.0
Total project cost (EUR): 1499375.0
EU funding (EUR): 1499375.0
Participants: 1
Project status: SIGNED

Sarcomas are an extremely heterogeneous group of mesenchymal tumors that arise in a multitude of tissues from many different cell types. Several genetic events have been identified in different sarcoma sub-types, but very few models were developed to study their role in tumorigenesis aiming at exploiting them as therapeutic vulnerabilities. As a result, the treatment of sarcoma has extremely limited advancement in therapeutic options compared to other cancers. Therefore, the generation of faithful in vitro and in vivo models for sarcoma research is urgently needed to provide insights into the pathobiology of these tumors and discover novel vulnerabilities in these lethal but yet understudied disease. Many types of soft tissue sarcomas arising in children and young adults have a unifying underlying genetic mechanism, where chromosomal translocations generate fusion oncoproteins that serve as drivers of the disease. Exploiting this genetic simplicity provides an exceptional opportunity to develop effective and specific therapies. My past research has applied cutting edge technology to define epigenetic vulnerabilities associated with the SS18-SSX gene fusion, the defining event in synovial sarcoma (one subgroup of pediatric sarcomas), and to study its chromatin occupancy genome-wide. In this proposal my team will combine a toolbox consisting of CRISPR/Cas9, RNAi technology and expertise in mouse models to systematically elucidate key genetic and epigenetic mechanisms in the pathobiology of pediatric sarcomas. This work will help to understand key players in epigenetic deregulation in pediatric sarcomas, generate new sarcoma models to assist clinical translation, and identify new therapeutic targets for these deadly diseases.
Manipulation Enhancement through Robotic Guidance and Intelligent Novel Grippers (MERGING)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Technologies for Factories of the Future
Action type: Research and Innovation actions
Countries involved: Spain,Spain,Italy,Switzerland,Greece,Greece,France,France,France,France,Netherlands,United Kingdom,Portugal
Call: Handling systems for flexible materials (RIA) (H2020-NMBP-FOF-2019, 2019)
Start date: 2019-11-01
End date: 2023-10-31
Duration (months): 48.0
Total project cost (EUR): 7622567.95
EU funding (EUR): 7622567.95
Participants: 14
Project status: SIGNED

MERGING will deliver a turnkey robotic solution to automate handling of flexible and fragile objects. Our ambition is to provide manufacturers with an end-to-end solution to automate the handling of soft objects. The solution will consist of a fingered gripper equipped with an electro-adhesive skin that conforms to the objects to handle, even delicate fabrics or components, without any damage. Electro-adhesion increases the direct gripping forces and thus allows greatly reduced clamping forces. Our solution includes perception and supervision functions to adapt the system's behaviour in real time to the execution conditions and for robot system programming accessible to non-specialists. Our main motivations are to build a versatile, easy-to-use and low-cost system. To demonstrate this and the possibilities of scaling up, we will design our system using proven laboratory technologies (TRL 4), then carry out proof of concept in realistic environments (TRL 6) in three different applications and sectors: fabric handling for lingerie manufacturing, technical fiber handling for composite bus panel manufacturing, plastic bag handling for the food industry. MERGING is a four-year project involving the entire value chain of soft object gripping automation. The CEA leads the project and provides the robotic technologies in collaboration with EPFL (electrical adhesion), AIMEN (perception), LMS (supervision), and SHADOW then OMNIGRASP (capture) and IPC (materials). CEA, EPFL, AIMEN and LMS will respectively use AI technologies for robotic demonstration programming, electro-adhesive skin control, perception and control of the complete system. SELMARK, VDL and THIMONNIER introduce cases of use of fabric, composite and polymer handling respectively. CASP and OPTEAMUM are respectively responsible for the software and hardware integration and the exploitation of the results. OMNIGRASP will release the pliers with electro-adhesive skin after the end of the project.
European methanol powered fuel cell CHP (EMPOWER)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Research and Innovation actions
Partnership: FCH2 (Art-187)
Countries involved: Finland,Sweden,Finland,Portugal,Denmark
Call: Development of highly efficient and flexible mini CHP fuel cell system based on HTPEMFCs (H2020-JTI-FCH-2019-1, 2019)
Start date: 2020-01-01
End date: 2023-11-30
Duration (months): 47.0
Total project cost (EUR): 1499876.25
EU funding (EUR): 1499876.25
Participants: 5
Project status: SIGNED

In the EMPOWER project a methanol fuelled 5 kWe mini-CHP system based on HTPEMFC technology is developed, manufactured and validated in a relevant environment. The system efficiency over 50% (DC, LHV) is achieved with novel ideas of thermal integration with a two-stage reformer setup and by using thermoelectric generators (TEG), utilising the high temperature heat of HTPEMFC stack. An aqueous phase reformer (APR) for methanol pre-reforming is applied for the first time in a commercial scale HTPEMFC system. The use of APR and its thermal integration in the FC system enables efficient utilisation of the stack waste heat and enables reformer efficiency approaching 95%. The best available catalysts will be screened and adapted for the reformer, both for the APR and for the 2nd stage reformer, which employs commercialised reformer technology from project partner Catator and recently developed methanol-reforming catalyst from partner University of Porto. The system efficiency is further improved by increasing the fuel utilization to above 95% in the HTPEMFC stack. This is enabled by improving anode gas flow distribution in the cells as well as improving the stack end plates. The new end plate design will also enable stack pressurising and improving stack efficiency over 55 %. The improvements in the HTPEM system design for mini-CHP use are validated in relevant environment, coupled to the heating and power system of a detached house, so that reliable data of the operation and stability can be generated. The accelerated test will be carried out for a period of 6 months and for at least 2,000 h of operation. Lastly, the project includes planning for scaling both the reformer solution and CHP system to 50-100 kWe size, including the addition of expanders. The technical work is complemented with a business analysis, including all the relevant elements of the methanol FC value chain, for the use of the developed technology in micro-CHP, CHP and maritime sectors.

Keywords: methanol,htpemfc,aqueous phase reformer,thermoelectric generator
Model Predictive Control and Innovative System Integration of GEOTABS;-) in Hybrid Low Grade Thermal Energy Systems - Hybrid MPC GEOTABS (MPC-. GT)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Germany,Spain,Belgium,Belgium,Belgium,Belgium,Finland,Sweden,Switzerland,Belgium,Czechia,Netherlands,Denmark,United Kingdom
Call: New heating and cooling solutions using low grade sources of thermal energy (H2020-EE-2016-RIA-IA, 2016)
Start date: 2016-09-01
End date: 2021-02-28
Duration (months): 54.0
Total project cost (EUR): 4243701.25
EU funding (EUR): 3969951.25
Participants: 18
Project status: CLOSED

The MPC-: GT project brought together a transdisciplinary team of SMEs, large industry and research institutes, experienced in research and application of design and control systems in the combined building and energy world. Based on prior research, supported by (joint) EU and national projects, and practical experience the bottlenecks where identified that prevent at this moment a real breakthrough of geothermal heat pumps (GEO-HP) combined with thermally activated building systems (TABS) - GEOTABS. Solutions, which need to be implemented in an integrated way, were identified and sufficient proof of concept was gathered to join forces in a RIA. The innovative concepts aim at increasing the share of low valued (low-grade) energy sources by means of using low exergy systems on the one hand and aim at upgrading low/moderate temperature resources on the other hand. The overall solution consists of an optimal integration of GEOTABS and secondary supply and emission systems. To allow for an optimal use of both the GEOTABS and the secondary system, a split will be made between a so-called “base load” that will be provided by the GEOTABS and the remaining energy needs that should be supplied by the secondary system. A generic rule, eliminating case-by-case simulation work, will be developed. The second part of the proposed solution aims at a white box approach for Model Predictive Control (MPC) to generate a controller model with precomputed model inputs such as disturbances and HVAC thermal power to avoid case by case development. Research is needed to assess the overall performance and robustness of such an approach towards uncertainties. As such, the MPC-: GT consortium believes to have identified an integrated solution that will provide a near optimal design strategy for the MPC GEOTABS concept using optimal control integrated design. The solution will support the industry, especially the SME members, to expand their activities and strengthen their competitiveness.

Keywords: model predictive control,hybrid,geothermal heat pump,thermally activated building,pcm ceiling,design,new building,retrofitting,offices,elderly houses,schools,collective residential houses