Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Improving scientific excellence and creativity in combating disinformation with artificial intelligence and language technologies (DisAI)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Slovakia,Germany,Greece,Denmark
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2022-12-01
End date: 2025-11-30
Duration (months): 36.0
Total project cost (EUR): 1499750.0
EU funding (EUR): 1499750.0
Participants: 4
Project status: SIGNED

The aim of the DisAI project is to enhance the scientific excellence of KInIT and the consortium partners in trustworthy AI and multimodal natural language processing and multilingual language technologies to combat disinformation. Disinformation spreading threatens European democratic values and tackling it is a European level priority. As the amount of disinformation grows, AI and in particular language technologies have a crucial role in detecting disinformation. To meet the European goals, it is increasingly important to develop tools and methods for disinformation combating also for low resource languages. KInIT, the widening partner from Slovakia, has taken a leadership role in shaping the R&I landscape of Slovakia by boosting cross-sectorial, interdisciplinary, and international collaboration. The ambition of KInIT is to strengthen AI to combat disinformation, an area that especially in Slovak digital space contributes to the development of AI technologies and tools for low resource languages and growing awareness of online disinformation. To achieve scientific excellence of KInIT, the activities of the project aim to increase the research capacity and excellence of scientists at different career levels in multilingual and multimodal language technologies and trustworthy AI. Together with leading partners German Research Center for Artificial Intelligence, Centre for Research and Technology Hellas and Copenhagen University, a joint Research project on claim matching as well as networking and mobility activities will be organised. Importantly, transfer of know-how on innovation and creativity for facilitating industry-academia collaboration and boosting the skills of the research managers and administrative staff will be part of the capacity building programme.

Keywords: disinformation combating,artificial intelligence,language technologies,scientific excellence,capacity building
MApping the Methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a LIving lab (MAMELI)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Italy
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-08-01
End date: 2028-07-31
Duration (months): 60.0
Total project cost (EUR): 2993251.0
EU funding (EUR): 2993251.0
Participants: 1
Project status: SIGNED

The concept of “exposome” encompasses all human disease determinants encountered during the life course. The exposome induces epigenetic modifications (e.g., DNA methylation). Several studies have investigated how repetitive elements (REs) can be switched on in response to environmental stimuli, but have started from the assumption that altered RE methylation is always detrimental to the health of the affected individual. MAMELI proposes an alternative hypothesis that some REs are plastic entities that respond physiologically to the environment; consequently, the ability of DNA to adapt to environmental triggers can be monitored. To test this hypothesis, the MAMELI project will enroll 6200 subjects in the city of Legnano (Italy). The first-level (“discovery”) will apply third-generation sequencing methylation assessment on 200 subjects at two-time points: T0 (baseline) and T1 (6 months after T0). The discovery level will allow me to define a pool of REs (“differential REs”) whose methylation can change without impacting genome stability. The second level (“tuning”) will be conducted on 2700 subjects (200 subjects of the discovery level + 2500 additional subjects) and will allow me to develop an algorithm (“MAMELI algorithm”) to predict the relationship between exposome and RE methylation status (“RE methylation signature”). In the third level (“validation”), I will apply the MAMELI algorithm on the second set of the study cohort (n=3500) to calculate the difference between the measured RE methylation signature and the values predicted by the algorithm. In addition, to test the reversibility of RE methylation following lifestyle modifications and its preventive potential, I will design an intervention study embedded in the cohort. MAMELI would represent a breakthrough in the understanding of individual susceptibility to environmental pressures, enabling the development of preventive strategies to avoid disease.

Keywords: repetitive elements exposome dna methylation
Industrial Technologies and Materials for Sustainable Europe (EUIndTech2025)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Cluster 4 other
Destination: Other Digital, Industry and Space destinations
Action type: Coordination and support actions
Countries involved: Poland
Call: Presidency Event (conference): Technologies for Europe 2025 (Driving Green Technologies and Materials in Industry (HORIZON-CL4-2024-PRESIDENCY-EVENT-2025-IBA, 2024)
Start date: 2024-11-01
End date: 2025-10-31
Duration (months): 12.0
Total project cost (EUR): 150000.25
EU funding (EUR): 150000.0
Participants: 2
Project status: SIGNED

Conference Industrial Technologies and Materials for Sustainable Europe is planned in Krakow on June 2-4, 2025 as part of the Polish Presidency of the Council of the European Union. It will be organized by the Mineral and Energy Economy Research Institute, Polish Academy of Sciences (IGSMiE PAN), the Division of Strategic Research, and Malopolska Voivodship (MV). Major topics and themes will be consulted with the Ministry of Science and Higher Education, which will also participate in event funding. The scope will cover aspects of sustainable industrial technologies and materials. It will be organized as a cyclical flagship event of the European Union - EUIndTech2025. Under the program of Horizon Europe‘s cluster 4: “Digital, Industry and Space”, the conference will mobilize key players worldwide around the theme of the industrial technologies of tomorrow, gathering stakeholders from scientific and research units, industrial companies, start-ups, European partnerships, administrative bodies and NGOs. EUIndTech2025 will focus on increasing the competitiveness and resilience of the EU industry and its transformation, having regard to the most important strategic developments in the area of manufacturing, net-zero industry, critical raw materials and advanced materials.

Keywords: conference,poland,presidency,industrial technologies and materials,sustainability
Creating a Rare Earth Circular Supply Chain, ensuring secure & sustainable supply of critical raw materials for EU industry & significantly reduce EU dependency on imports from single country supplier (Magnet Circular)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 1980000.0
EU funding (EUR): 1980000.0
Participants: 1
Project status: SIGNED

Ionic Technologies (IOT) proposes a world first commercial scale plant in Belfast Harbour, Northern Ireland, transforming waste magnet materials from Rare Earth Permanent Magnets (REPMs) into premium quality Rare Earth Oxides (REO). A challenge for the EU is to meet its climate objectives, sourcing, processing and recycling critical raw materials in Europe and securing supply chains. With the CRMA, the EU aims to ensure secure and sustainable supply of critical raw materials for EU industry and significantly lower the EU’s dependency on imports from single country suppliers. With IOTs breakthrough technology in recycling Rare Earth Elements from spent magnets, we can play a strategic role in helping the EU achieve the aims of the CRMA and help to address the dominance of China in the supply chain. IOT have a vision to create a circular supply chain in the EU by working with strategic partners across Europe. This will enable OEMs in the Wind Turbine, EV, Defence and other strategic industries to recycle their spent REPMs to produce a new REPM that can be used in a new wind turbine, electric vehicle etc. Originally founded in 2016, in April 2022 we custom built our own laboratories, pilot plant and demonstration plant in the Titanic Quarter, Belfast, Northern Ireland. This is a very strategic location for IOT. Due to the Windsor Framework, we have frictionless movement of goods between the EU and UK. We want to use EIC funding to evidence the circular supply chain from beginning to end by recycling end-of-life REPMs from an Enercon wind turbine to produce a new wind turbine. This process would also enable IOT to become an accredited Enercon supplier and gain a commercially significant supplier contract to increase the opportunity of success. This accreditation process from recycling to circular supply to finished product would take ca 2 years. Our feasibility study (by WSP) and funding from EIC will ensure that we have full understanding of our OPEX costing.

Keywords: rare earth elements,critical raw materials,ev and wind turbines,circular supply chain,recycling permanent rare earth magnets reduce reliance on china
Silicon Through holes by Accumulative interplaY of 2 Micron short pulsEs (STAY2ME)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: France,Czechia,Germany,Belgium
Call: EIC Pathfinder Open (HORIZON-EIC-2025-PATHFINDEROPEN, 2025)
Start date: 2026-04-01
End date: 2030-03-31
Duration (months): 48.0
Total project cost (EUR): 2998687.5
EU funding (EUR): 2998687.5
Participants: 7
Project status: SIGNED

At a time when digitalization is omnipresent in our daily lives and silicon-based devices remain a key factor, the demand for high-density interconnections and increasingly compact, reliable electronics is essential for the continued advancement of semiconductor technologies. Through-Silicon Vias (TSV), the vertical interconnects that make true 3D integration possible in CMOS chips, MEMS sensors, and AI hardware play a key role. The STAY2ME project lays the foundation for a radical shift in how silicon structures that drive tomorrow’s technologies can be shaped and connected. Our radically innovative laser-based technology enables non-contact, chemicals-free, high-aspect-ratio micro-drilling within silicon, delivering unprecedented precision without detrimental side-effects in the surrounding material. This will be a game-changer for fabricating TSV. At the core of this innovation is a mJ-energy class laser operating at 2 micrometers in the novel GHz-burst regime, where a rapid train of pulses is delivered in ultrashort bursts. This laser combines the right wavelength with the right pulse dynamics, achieving nonlinear absorption and how energy accumulates in silicon-thus avoiding the laser beam distortion and chaotic energy deposition that plague existing methods. It could outperform the precision, speed and sustainability of Deep Reactive Ion Etching, today’s state-of-the-art for TSVs, and transforms what was once a materials limitation into a design revolution. Understanding and controlling how such a laser interacts with silicon is a breakthrough, opening a fundamentally new regime of laser-based silicon processing which offers unprecedented control over the drilling process. One of the unique strengths of this project lies in its interdisciplinary consortium, bringing together specialists from physics, chemistry, electrical and mechanical engineering, and thus, covering all facets and know-how to successfully carry out the STAY2ME project.

Keywords: ultrafast laser,ho doped laser,ghz burst laser,ultrafast laser processing,drilling,silicon,through silicon via tsv,swir photonics
seXYt—Non-invasive in-ovo sexing of chicken eggs pre-incubation to avoid culling of hatched male chicks (seXYt)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Each year the layer chicken industry incubates 14bn chicken eggs in hatcheries. After hatching, their sex is determined manually by chicken sexers. Male chickens (50% of eggs) are considered waste and are culled (disposed of). Culling is a massive ethical and financial challenge globally. Market-ready in-ovo sexing is usually invasive and requires 9-13 days of incubation. Such solutions pose a risk of egg cross-contamination due to piercing through the eggshells. 9+ days of incubation also consume energy and render eggs difficult to repurpose as they already contain embryos. Our CRISPR/Cas9-based solution places a luminescent biomarker on the male chromosome, making the sex of the chick detectable through the shell on the day of lay. eggXYt will save €1.5bn in OPEX for hatcheries, reduce incubation costs and CO2 emissions and add 7bn eggs per year to the global egg supply for the other industries. eggXYt will also help shape an ethical poultry farming industry.

Keywords: culling prevention,ethical eggs,sex determination,layer chickens,hatcheries,chicken genetics,incubation,male chick culling free eggs,industrial bioengineering,in ovo sexing,
Medical nanofiber technology to prevent cerebrospinal leakage in neurosurgeries (Nurami)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2024-12-01
End date: 2026-05-31
Duration (months): 18.0
Total project cost (EUR): 3565177.14
EU funding (EUR): 2495624.0
Participants: 1
Project status: SIGNED

Cerebrospinal fluid (CSF) leaks is a major post-neurosurgical complication that occurs in 4% to 32% of neurosurgeries, depending on the surgical site. It impacts millions globally, causing life-threatening infections and costs the EU an estimated €330 million each year. Prevention requires proper sealing and healing of the Dura Mater. Current dural repair treatments are suboptimal, leading to long hospital stays, extended recovery, and a high economic burden on healthcare systems. To address this, Nurami has developed ArtiFix, a bio-absorbable, biocompatible patch, designed to seal and repair the dura and prevent CSF leaks. It features an adhesive layer for sutureless fixation and watertight sealing, plus electrospun nanofibers that promote healing of the dura. ArtiFix will be the first and only, 3-in-1 solution for dural repair on the market. It uniquely combines a sealing and healing solution that also adheres to the surgical site, even to wet tissue. ArtiFix is a new category of suture-less sealing patches targeting dural repair. It is both a Dura substitute and a sealant patch, in a single, easy to apply solution. ArtiFix will therefore replace current Dural repair products which include dura substitute patches, liquid sealants and sutures. By reducing extra surgeries, hospitalisations, and long-term care, ArtiFix will improve patient outcomes and reduce the costs of cerebrospinal complications. ArtiFix is a platform adhesive patch, which can be fine-tuned for implementation in numerous additional surgical procedures. In this manner, Nurami will capitalize on large, underserved and growing multi-billion-dollar market opportunity with significant commercial opportunities. Nurami has an outstanding multidisciplinary team supported by strong scientific advisory board and active board of directors, and is capital efficient being able to achieve preliminary product commercialization for its first product in pipeline following total funding to date of only €14.8M.

Keywords: dura mater,cerebrospinal fluid,csf,neurosurgery,medical device,
Plastigram - Powering Sustainable PolyAl Solutions (Plastigram)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Czechia
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Each year, Europe uses about 1 million tons of food and beverage cartons. 250,000 tons of plastic and aluminium components from these cartons remain largely unrecycled, with the majority being incinerated. This practice not only wastes valuable materials but also contributes to significant CO2 emissions of 593 000 tons per year from plastic incineration alone. The challenges of recycling PolyAl stem from the complexity of its multi-layer composition, comprising strongly bonded polyethylene and aluminium with incompatible properties like ductility, melting points and abrasivity. These problems are compounded by contamination from imperfect waste sorting and material degradation during manufacturing and recycling. Existing recycling methods fail to provide scalable, cost-effective, or environmentally friendly solutions. Our proposed technology uses an innovative Plastigram patented recycling process based on separating aluminium and polyethylene using an aqueous formic acid solution with the process of separation being preceded and followed by proprietary mechanical treatments based on our specific design. The result is high-quality recycled plastics with 0% aluminium contamination, and aluminium powder, that can be reused in higher value products across industries. Closed-loop chemical system further minimises chemical waste. As a result, our proposed technology results in high material recovery with high-purity plastics and aluminium powder, is cost-efficient and proven on an industrial scale, while reducing CO2 production by >85% compared to incineration.

Keywords: recycling,polyal,polyaluminium,composite packaging,multi layer packaging,beverage cartons
Real-time automatic monitoring and ML-based prediction of pest insects (xTrap)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-02-01
End date: 2025-01-31
Duration (months): 24.0
Total project cost (EUR): 1243750.0
EU funding (EUR): 870625.0
Participants: 1
Project status: CLOSED

xTrap is an innovative smart trap solution that will transform pest management operations in farms, fostering the transition towards the Agriculture 4,0 era. It combines real-time automatic monitoring of pest insects with prediction based on machine-learning models. xTrap is the first predictive solution for pest life-cycle events (over 95% accuracy) on the market. It accurately identifies crop pests and diseases in time, therefore allowing farmers to prevent them effectively. xTrap includes two main functions: 1) automatic insect detection through smart traps equipped with sensors and high-resolution cameras to count and identify insects by means of machine-learning algorithms, and 2) pest prediction through algorithms based on environmental data and phenology of insects combined with the use of artificial intelligence. The output from the algorithms and the predictive models will be available to farmers through our digital platform currently being commercialized by xFarm.
Magnetically induced nano-forces in neuromuscular organoids for disease modeling (NanoMag organoids)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 202125.12
EU funding (EUR): 202125.12
Participants: 1
Project status: SIGNED

*Neuromuscular disorders, whose incidence and prevalence have increased over time have currently no cure, and understanding their pathological mechanisms remains challenging due to the lack of reliable human in vitro models. A groundbreaking approach involves human 3D trunk neuromuscular organoids (NMOs) that replicate the cellular diversity and the functional dynamics of the neuromuscular system. However, the absence of in vivo-like external stimulations leads to reduced contractions and prevent terminal maturation, restraining their applicability for studying long-term neuromuscular diseases. The primary goal of this project is to design innovative multi-disciplinary approaches to mimic in vivo mechanical and brain inputs and provide new paradigms for organoid generation. A new method will be developed to apply spatiotemporally controlled nano-forces within NMOs, with the aim of enhancing the maturation of both the neural and muscle tissue. Additionally, magnetically induced nano-forces will be exploited to guide the reconstruction of the corticospinal tract within newly generated cerebral-NMOs and integrate brain inputs. Cutting-edge imaging, optogenetics, and single-nucleus RNA sequencing will be used for in-depth characterization of the outcomes. The hypothesis is that these stimuli will significantly promote NMOs maturation, resulting in a more sophisticated model for neuromuscular disease research. As case-study, the enhanced NMOs will be applied to model and explore the complex pathological mechanisms of X-linked spinal and bulbar muscular atrophy (SBMA). Patient-derived nano-forced cerebral-NMOs will be generated to investigate the impact of SBMA on neuromuscular system and corticospinal tract. Supporting this project will enable the implementation of innovative methodologies for the optimization of a relevant human in vitro system, with the potential to revolutionize research and treatment approaches for neuromuscular diseases.

Keywords: organoids,neuromuscular system,mechanical forces,magnetic nanoparticles,tissue maturation,disease modelling