Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Interdisciplinary training network for Tourette Syndrome; structuring European Training capacities for neurodevelopmental disorders. (TS-EUROTRAIN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Greece,Iceland,Hungary,Denmark,Netherlands,Netherlands,Germany,Germany,Germany,Netherlands
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2016-12-31
Duration (months): 51.0
Total project cost (EUR): 3076397.9
EU funding (EUR): 3076397.9
Participants: 11
Project status: CLOSED

There is a striking lack in structured and standardized training infrastructure for neurodevelopmental disorders across Europe. Such training will be fundamental to promoting standards of care across Europe and will ultimately lead to strategies for the promotion of childhood mental health in Europe. The focus of this Initial Training Network (ITN) is Gilles de la Tourette Syndrome (TS), an inherited neuropsychiatric disorder that provides an excellent paradigm for the study and training needs for neurodevelopmental disorders of childhood onset. TS is marked by multiple motor and vocal tics and high comorbidity rates with attention deficit hyperactivity disorder and obsessive compulsive disorder. Due to lack of education of medical professionals, educators, and the general public, TS is underdiagnosed and patients are severely discriminated against. Efforts to elucidate the etiology and pathophysiology of TS are fragmented across Europe and hampered by low statistical power. Standards of care are not uniform due to lack in structured training modules for this disorder. We have built an comprehensive interdisciplinary and intersectorial training program in the field of TS and related disorders, that will deliver the next generation of young researchers who will shape the field in Europe and around the world. Their research within this ITN will lead to discoveries that will ultimately provide new therapies and increase the quality of life for patients and their families. At the same time, their engagement to society will increase awareness about the disorder in a pan-European effort to promote childhood mental health across Europe.

Keywords: tourette syndrome,l512 psychiatric disorders,neurodevelopmental disorders,l209 genetic epidemiology,l510 neuroimaging and computational neuroscience
Adjoint-based optimisation of industrial and unsteady flows (ABOUTFLOW)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,France,France,Greece,Germany,Germany,Poland
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-11-01
End date: 2016-10-31
Duration (months): 48.0
Total project cost (EUR): 3810946.37
EU funding (EUR): 3810946.37
Participants: 9
Project status: CLOSED

Adjoint-based methods have become the most interesting approach in CFD optimisation due to their low computational cost compared to other approaches. The development of adjoint solvers has seen significant research interest, and a number of EC projects have been funded on adjoint-based optimisation. In particular, partners of this proposal are members of the EC FP7 project FlowHead which develops complete adjoint-based design methods for steady-state flows in automotive design. Integration of the currently available shape and topology modifcation approaches with the gradient-based optimisation approach will be addressed, in particular development of interfaces to retun the optimised shape into CAD for further design and analysis, an aspect that currently requires manual interpretation by an expert user. In industrial practice most industrial flows have small levels of instability, which leads to a lack of robustness and instability of the adjoint, such as trailing edge vortex shedding in turbo-machinery. Many industrial applications are also partly unsteady such as bluff body separation in cars or fully unsteady such as vertical-axis wind turbines. In unsteady adjoints 'checkpoints' of the flow solution at previous timesteps need to be recorded and algorithms for an effective balance between storage and recomputation need to be implemented. The recomputation involves significant memory and runtime overheads for which efficient methods are developed and implemented. The results of the project will be applied to realistic mid-size and large-scale industrial optimisation problems supplied by the industrial project partners ranging from turbo-machinery, to automotive to wind-turbines. Training will be provided by academic, industrial and SME partners in methods development, industrial application and software managment. A large programme of complementary training in professional skills will be provided with support from all partners.

Keywords: g110 scientific computing,g203 simulation engineering and modelling,g304 computational engineering
Industrial Biological Biomaterials Doctorate (IB2)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Portugal,Spain
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-12-01
End date: 2016-11-30
Duration (months): 48.0
Total project cost (EUR): 821217.97
EU funding (EUR): 821217.97
Participants: 2
Project status: CLOSED

The present proposal consists in an elite doctorate program designed to train PhD candidates at the highest academic level in combination with strong components in entrepreneurship, technology transfer and business development since part of the research and training will be carried out in an industrial environment and using a problem solving approach. The major scientific objective of this project is to grow stem cells of human origin in xenofree conditions. Currently, the clinical applications of human cells are limited partly because they are cultured using serum of bovine origin, thus with high risk of immunogenic reactions or zoonotic disease transmission. Human plasma-derived biomaterials, which are a priority of research and development of the industrial partner, are here proposed as an alternative supplement for cell culture. If successful, this proposal would profoundly impact on clinical transplantation of stem cells. The coordinating partner, INEB, is a relevant European research institute in biomedical engineering, specialized in the development of innovative biomaterials and cell therapies. The industrial partner is Grifols, a major healthcare company that produces life-saving protein therapies. The other partners involved are IBEC, a highly multidisciplinary research institute with well-established collaborations both with INEB and Grifols, and University of Porto and IPATIMUP, which will consistently contribute to the training program. The training program is designed to create PhDs with an entrepreneurial mindset. It involves a high quality multidisciplinary research environment, inter-institutional cooperation and international networking, and provides career development by adding the technological dimension through inclusion of a comprehensive range of transferable skills (e.g. entrepreneurship courses, career development counselling, etc.).

Keywords: g311 materials engineering,g314 medical engineering and technology,l705 gene therapy - stem cell therapy - regenerative medicine
Gauge Theory as an Integrable System (GATIS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Germany,United Kingdom,United Kingdom,France,Sweden,Portugal
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 3958581.67
EU funding (EUR): 3958581.67
Participants: 8
Project status: CLOSED

Gauge Theories provide the most successful framework for the description of nature at its most basic level, and in particular of high energy physics. However, extracting reliable predictions relevant for experiment from gauge theory has remained a major challenge which so far requires massive use of computer algebra. Over the last decade an entirely new approach to quantum gauge theories has begun to emerge, initiated by a celebrated duality between gauge and string theory. This has brought an area of science into gauge theory that seemed unrelated a few years before, namely the theory of low-dimensional statistical systems and strongly correlated electron systems. The paradigm governing this is to view "Gauge Theory as an Integrable System". The partners of this proposal represent different communities from gauge theory, statistical physics and computer algebra. With the proposed Initial Training Network we will carry the emerging multidisciplinary interaction to an entirely new level, bridging the gaps between our research fields in the context of graduate training activity. We believe that coordinated education of young scientists in all the tools under development from the different communities offers tremendous potential to make progress in the understanding and application of gauge theory. This will help to secure Europe's leading role in this important area of fundamental research. A group of carefully selected private sector partners will assist dissemination of results, methods and ideas into neighboring scientific disciplines as well as to the general public. At the same time, they will also be vital in preparing the early stage researchers for active and leading roles in academia and beyond.

Keywords: p101 fundamental interactions and fields
Design & Engineering of Photosynthetic Communities for Industrial Cultivation (PHOTO.COMM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark,United Kingdom,United Kingdom,Finland,Germany,Israel,Portugal,United Kingdom,Germany,Spain
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-10-01
End date: 2016-09-30
Duration (months): 48.0
Total project cost (EUR): 3925588.62
EU funding (EUR): 3925588.62
Participants: 11
Project status: CLOSED

The generation of young biotechnologists is of paramount importance for Europe´s future. PHOTO.COMM will train primarily early stage researchers who have demonstrated high ambitions and talents in a unique platform based on emerging technology and science that would shape the forefront of future European biotechnology. PHOTO.COMM involves the utilization of microalgae for the conversion of carbon dioxide and water into chemicals and fuels, to directly replace finite fossil fuels and products. Although this is a rapidly growing industry, true societal impact cannot be expected until larger-scale production of low value end-products becomes a commercial reality. PHOTO.COMM has the primary objective of generating the next-generation scientists that will make a substantial and potentially game-changing contribution towards this global challenge. The young researchers will be trained in multidisciplinary science and innovation-based business creation to foster a new approach to microalgae based production and the use of synthetic photobiological communities. The researchers will also strengthen the core of photobiological metabolism by innovative approaches to enhance photosynthesis and carbon-assimilation and deliver new approaches to create valuable end-products. PHOTO.COMM will provide an exciting environment where the young researchers will absorb and implement state-of-the-art analytical methods, intellectual property and business principles and obtain extensive training and practical experience in close collaboration between universities and companies. Altogether, the educated next-generation scientists and their technologies are expected to make a strong contribution towards a future Europe in which both economically and environmentally sustainable photosynthetic biotechnology is a main supply of commodities and energy.

Keywords: industrial training,microalgae communities,systems biology,synthetic communities,metagenomics,metabolic engineering,photosynthesis,sustainable production,cyanobacteria,algae,bioreactors
GLANAM (Glaciated North Atlantic Margins) (GLANAM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Norway,United Kingdom,United Kingdom,United Kingdom,Denmark
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-04-01
End date: 2017-03-31
Duration (months): 48.0
Total project cost (EUR): 4464245.39
EU funding (EUR): 4464245.39
Participants: 8
Project status: CLOSED

GLANAM (Glaciated North Atlantic Margins) aims at improving the career prospects and development of young researchers in both the public and private sector within the field of earth science, focusing specifically on North Atlantic Glaciated Margins. Our multi-Partner ITN comprises ten partner institutions, both academic and industrial, from Norway, UK and Denmark and will train eleven Early Stage Researchers (ESRs) and four Experienced Researchers (ERs). The young scientists will perform multi-disciplinary research and receive training through three interconnected workpackages that collectively address knowledge gaps related to the large, glacial age, sedimentary depocentres on the North Atlantic Margin. Filling these gaps will a) result in major new insights regarding glacial age processes on continental margins, b) have particular impact on the exploitation of hydrocarbons in glacial age sediments, notably the gas hydrate energy potential on the European continental margin, c) provide paleoclimate information essential for understanding the role of marine-based ice sheets in the climate system and for the testing of climate models, an issue of increasing socio-economic relevance. GLANAM builds on the diverse expertise and experience of leading senior and junior scientists in the field of marine and glacial geology through the establishment of a training program offering a broad spectrum of career-oriented courses and tailored workshops preparing the researchers for an increasingly demanding, pan-European job market. Intersectoral rotation and secondments hosted by our three industry partners will provide the fellows with complementary scientific training and allow them to establish and deepen contacts relevant to their work life beyond the ITN. Interaction of the GLANAM Fellows with internationally renowned senior visiting scientists will provide significant added-value to their training and will complete the supply of knowledge and advice sources.

Keywords: marine geology,glaciated margins,geological hazards,gas hydratv201 geology - tectonics - volcanology,v201 paleoclimatology - paleoecology,v201 natural resources exploration and exploitatio
Frontiers in Quantum Technology (FQT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-09-01
End date: 2017-08-31
Duration (months): 48.0
Total project cost (EUR): 3816691.12
EU funding (EUR): 3816691.12
Participants: 1
Project status: CLOSED

Mission Statement: To deliver an internationally competitive student cohort who will be equipped to be the research and industry leaders of the future through interdisciplinary training at the frontiers of Quantum Technology. The ability to engineer materials at the atomic level has led to the enormously active field of nanotechnology: the analysis, design and fabrication of devices that operate at the leading-edge of optical and electronic technology. This technology has inevitably revealed the true quantum nature of the microscopic world, where particles and waves co-exist and interact in novel exciting ways. The study of quantum information and quantum technology has now been around for some time, and this is the ideal opportunity for the fundamental science to work with industrial researchers to make advancements which the market wants, rather than those which serve only the scientists’ curiosities. Along this line, we have identified two strands of research themes, namely, the generation of extreme light sources and the study of light-matter interactions, with a view to the development of quantum technology. Imperial College has a large team of researchers (17 members of academic staff and 50 postdoctoral fellows: research grants over £30m) working at the leading edge of quantum sciences encompassing surface plasmonics, cold atoms, attosecond lasers and quantum theory. Coupled with newly refurbished postgraduate lecture facilities, a brand new state-of-the-art workshop, and new offices for the quantum theory group this makes Imperial ideal for student training. The associated partners include top academic institutes, government labs and private companies which will be actively involved in student recruitment, research and training. Imperial has been known for attracting world’s best students and with the current IDP we will be able to train those students to become leading scientists with the creative ideas to answer the beneficiaries’ needs.

Keywords: p108 optics and quantum optics,p107 atomic - molecular physics,quantum information,attosecond lasers,surface plasmons,cold atoms,ion traps
EID on the advanced science and technology of rat models for neurodegenerative diseases (PHENORAT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany,Netherlands
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2012-11-01
End date: 2016-10-31
Duration (months): 48.0
Total project cost (EUR): 924516.78
EU funding (EUR): 924516.78
Participants: 2
Project status: CLOSED

One of the most important bottlenecks for finding more effective drugs for brain disorders is the development of model systems that translate to human pathology and are predictive of clinical efficacy. To address this bottleneck PhenoRat will focus on the generation, characterisation and validation of transgenic rat models of two neurodegenerative diseases: Huntington disease (HD) and spinocerebellar ataxia type 17 (SCA17). For this purpose we have assembled a unique consortium in which industry (Noldus Information Technology and Delta Phenomics), academia (University of Tuebingen), and a university-related foundation for entrepreneurship (StartLife) will work closely together to achieve both organization of an excellent training program and excellent research projects with a pronounced focus on intersectoral doctoral education and transfer of knowledge. Two rat models, one already established model for SCA17 and one to be newly generated knock-in rat model of HD, will be behaviourally characterized using a unique integrated system based on video tracking and operant testing in a home cage situation. In addition, innovative behavioural paradigms will be developed to test for the cognitive and emotional impairments typically seen in SCA17 and HD. These findings will be extended with more sophisticated methods to assess fine motor coordination and gait abnormalities. Besides traditional methods of analysis of behavioural data, new statistical methods will be developed to enable behavioural classification of transgenic and wild type animals. This will enable the detection of early onset of specific symptoms and provide read-out parameters in pre-clinical studies applying novel substances for the treatment of HD and SCA17. Last but not least these read-outs will be validated in a gene therapy study with SCA17 rats using Antisense Oligonucleotides (AONs) against the PolyQ stretch of TBP.

Keywords: neurodegenerative disease,animal model,rat,technologies and tools for advanced behavioural testing,home cage testing,bioinformatics,gene therapy
Conceptually new, multi-scale solutions to industrial flow problems. (MULTISOLVE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Initial Training Networks
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2012-ITN, 2012)
Start date: 2013-04-01
End date: 2017-03-31
Duration (months): 48.0
Total project cost (EUR): 3816682.0
EU funding (EUR): 3816682.0
Participants: 1
Project status: CLOSED

Efficient use of energy and suppression of environmental pollution due to harmful emissions and noise (e.g. from aircraft near urban areas) are of paramount importance for sustainable development. New techniques are urgently needed for process intensification, reduced fuel consumption, pollution and noise. The central aim of this proposal is to address some of these problems by applying a new class of multi-scale turbulent flows that have a unique feature: they can be specifically designed for efficiency enhancement in many applications. Research in the past 10 years has demonstrated the power of these flows for process intensification, mixing enhancement, noise suppression and increased lift to drag ratios for wings of a given surface area. Many different industrial sectors such as the mixing, aeronautical, automotive, power generation and wind engineering industries can benefit from this work. Seven private companies operating in these sectors are associate partners in the proposal. Application examples include new static and dynamic mixers, silent spoilers, new efficient blades and wings suitable for aeronautical, racing car and wind energy applications, improved heat exchangers suitable for process or nuclear industries etc. In this IDP, we place particular emphasis on the quality of the training and learning experience of the early career researchers (13 in total) who will take part: we have put together an extensive training programme of 32 sets of lectures from academic and industrial partners and all researchers/engineers will be seconded to one or more academic or industrial institutions. The training includes a wide panoply of experimental and computational tools of the broadest applicability. We see this programme as the beginning of an activity with much larger scope to bring multi-scale bespoke flow concepts from the academic lab to industry together with the engineers who will have the technical background to help industry produce innovative products.

Keywords: g305 fluid mechanics - hydraulic- - turbo- - and piston engines,g301 aerospace engineering,g203 simulation engineering and modelling