Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
COMPARATIVE EDUCATION THEORY (CETH)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2013-04-01
End date: 2015-03-31
Duration (months): 24.0
Total project cost (EUR): 231547.2
EU funding (EUR): 231547.2
Participants: 1
Project status: CLOSED

The proposed project is an interdisciplinary theoretical investigation in the field of comparative education studies. The main purpose is to create a knowledge base intended to contribute to our understanding of education systems across cultures, under the conditions created by the Europeanisation and globalisation of education policy. These novel conditions indicate that it is time to improve our theoretical and methodological tools in Comparative Education, and allow for the production of new knowledge in this field. In attempting to do so, the project sets three main objectives: to generate a new theoretical understanding of education systems as social institutions; to produce an original account of the epistemological background of educational comparison; to propose a theoretical approach with regard to the comparability of education systems, now increasingly subject to transnational forms of policy making. To achieve these objectives the project will: theorise on the instituting of education systems, drawing on a variety of disciplines; engage with cross-historical and cross-cultural inquiry into the genesis and expansion of education systems and of educational comparison in Europe; apply its theoretical approach and develop it further through this inquiry. The proposal coordinator has considerable research and teaching experience in this field. The IEF, as outlined in 2011 Work Programme, will give him the opportunity for competence development in theoretical and interdisciplinary research which will enable him later on to make original contributions to the field. Moreover, the IEF will assist him to achieve a senior position at his home institution and establish his own research centre in Comparative Education. The researcher will be hosted by Humboldt University, which, due to the cutting-edge theoretical work of Jürgen Schriewer in the field, is perhaps the best and certainly the most appropriate place to carry out this project.

Keywords: educational sciences,sociology,history,anthropology,cultural studies,philosophy,psychoanalytic studies,neurobiology,literature,arts,political sciences,economics.
Control of flowering time by chromatin remodelling (FLOWERING CHROMATIN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-07-16
End date: 2014-07-15
Duration (months): 24.0
Total project cost (EUR): 233705.2
EU funding (EUR): 233705.2
Participants: 1
Project status: CLOSED

One of the most exciting aspects of plant science today is how much it contributes to general concepts in biology. The ability to combine a genetic analysis with detailed molecular and biochemical approaches offers real advantages for mechanistic analysis. A fascinating aspect of plant development and an economically very important trait is the switch from vegetative to reproductive development. Flowering time is the most studied developmental transition in plants and our molecular understanding of the genetic pathways regulating flowering time has explained the physiological characteristics that have intrigued biologists for over a century. Many flowering time genetic screens have identified a series of chromatin activities conserved among most complex organisms. The study of this conserved chromatin factors are not only relevant for plant development but for human cells as well because their misregulation is often associated with diseases such as cancer. I propose to study the interplay between SWR1 and NuA4 chromatin remodelling complexes in the control of flowering time. This innovative proposal differs from conventional flowering time studies by using genetic analysis combined with high-resolution chromatin immunoprecipitation experiments and protein complex purification. Collected data will allow comparison with the situation in non-plant systems, which will help the research community to develop a mechanistic consensus model on chromatin regulation in different kingdoms and further broaden our understanding on fundamental cellular processes. Moreover, comprehensive understanding of the fundamentals of flowering time will allow enhancement of crop performance by modulating this trait at the molecular level and will thus be of great value to address the problems of food security that our society will be facing with the postulated global climate changes ahead.

Keywords: plant genetics,flowering time,chromatin,epigenetics
Astrocytes in aging brain exhibit altered glutamate homeostasis: Implications for age related cognitive decline? (ASTROAGE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Denmark
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-07-01
End date: 2014-06-30
Duration (months): 24.0
Total project cost (EUR): 228082.2
EU funding (EUR): 228082.2
Participants: 1
Project status: CLOSED

Aging affects the brain in many ways, most notably by impairing memory function. On a cellular level, aging causes changes in synaptic plasticity and downregulation of energy metabolism. As our understanding of the importance of astrocytes in brain is increasing, it is clear that the knowledge on how aging affects astrocytes is lacking. The aim is, therefore, to elucidate the role of astrocytes in aging and how homeostasis of the neurotransmitter glutamate and energy metabolism alters with age and how this correlates to cognitive decline. The approach is to investigate astrocyte uptake of glutamate and energy metabolism in hippocampal slices from neonatal, adult and aged mice. Initially the effects of aging on astrocyte glutamate uptake will be quantified by measuring synaptically evoked glutamate transporter currents. Alterations in metabolic pathways will be evaluated by 13C metabolic mapping employing mass spectrometry and NMR spectroscopy. Besides being an excitatory neurotransmitter, glutamate is a substrate for energy production via conversion to a-ketoglutarate by glutamate dehydrogenase (GDH). Increased input of glutamate into the TCA-cycle may counteract a reduced energy metabolism during aging. Therefore, I will investigate the effect of GDH activity during aging, using a GDH knock out mouse and a transgenic model expressing GDH2 in addition to GDH1. To correlate the effects on uptake and metabolism to cognitive decline, I will investigate the effect of GDH activity on synaptic plasticity and spatial memory. By measuring long term potentiation in hippocampal slices and evaluating spatial memory capacity of the animals, I will be able to draw conclusions concerning the effect of altered glutamate homeostasis on cognitive decline. The project takes a grip on the issue of astrocytes in cognitive decline and aging from both the in vivo and in vitro angle. Therefore, it will contribute with new, valuable information on the role of astrocytes in the aging brain.

Keywords: neurochemistry,brain,astrocyte,aging,glutamate,energy metabolism,cognitive decline,neuron,hippocampus,ltp,spatial memory
Transition to turbulence in ventilated double glazing (T2T-VDG)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-09-17
End date: 2014-09-16
Duration (months): 24.0
Total project cost (EUR): 278807.4
EU funding (EUR): 278807.4
Participants: 1
Project status: CLOSED

Pioneering numerical techniques, that have not been employed before concurrently, are proposed in this project. They can capture the transition to turbulence of shear flow and in the process offer the capability of proposing methods for the state of the art control of such transitions. The proposed methods can enhance the calculation of fluid flow by identifying the hierarchical bifurcation of the evolving states and can be captured in an engineering orientated software (computational) tool that will aid the real life implementation of these, otherwise, generalised but tried mathematical techniques. In this sense the predictive power of the underlying mathematical modelling techniques, upon which the engineering tool will be crucially dependent, will display their true potential. The novel methods can be used to pinpoint the transition of the flow from its laminar (basic) state to its fully developed (turbulent) state with pinpoint accuracy and for arbitrary geometrical configurations. The ensuing stability analysis will be a unique attribute of this mathematically engineered software. Our software, in brief, that unifies the above mentioned techniques, will be able to oversee the development of the fluid flow throughout its evolution, from birth to turbulent arrival. It is the ultimate aim of this set of programmes to apply the resulting software to complex configurations applicable to a variety of every day engineering configurations. Simple geometries will be considered at first to act as benchmarks and common ground for the two different state of the art software avenues at our disposal: the proprietary code developed at Aston University and a commercially available CFD code. We intend to use the results of our studies for the design and industrial implementation of a new concept that is at the heart of European energy, environment and socioeconomic focus: ventilated double glazing.

Keywords: physical sciences,applied mathematics,chaos theory,3 d modelling,bioinformatics,nuclear engineering
Transferring Good Governance in the EU´s Neighbourhood (EUTRANSGOV)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-09-01
End date: 2015-03-03
Duration (months): 24.0
Total project cost (EUR): 269096.4
EU funding (EUR): 269096.4
Participants: 1
Project status: CLOSED

EUTRANSGOV concentrates on the transfer of good governance / institution-building (‘soft’ norms) in the EU’s neighbourhood, a topic which has attracted further attention since the revolutions in North Africa. Policy transfer gained momentum in International Relations and EU Studies to highlight changes within and outside the EU. This project complements research on EU enlargement and the European Neighbourhood Policy (ENP) in establishing an interdisciplinary cartography of the various approaches in “Policy Transfer Studies”. Its analytical framework, combined with an original methodology, allows for the identification of unexplored empirical case studies and transferable knowledge on successful (or less successful) norm and policy transfers in EU external relations. Three objectives need to be fulfilled to accomplish the project: Objective 1: to clarify the concepts of policy transfer and related notions in EU external relations. Objective 2: to elaborate an analytical framework with a pluralist methodology. Objective 3: to enhance empirical knowledge on the transfer of good governance in the EU’s neighbourhood. As results, the applicant expects: - to contribute greatly to academic debates in clarifying the use of policy transfer and good governance in EU external relations; - to advance the knowledge on the concrete ('real world') functioning of EU foreign policy and on its impact in the EU’s direct neighbourhood and abroad; - to enhance the visibility of the applicant’s past and current research activities for the applicant’s own career advancement.

Keywords: international relations,european studies,policy transfer,good governance
Creation, evaluation and characterization of the ideal bioprobe for the cancer antigen Tn by improved selection of mutant lectins from phage display libraries (TNSPECIFIC_LECT_EVOL)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2011-IOF, 2011)
Start date: 2012-03-01
End date: 2014-08-31
Duration (months): 30.0
Total project cost (EUR): 225615.75
EU funding (EUR): 225615.75
Participants: 1
Project status: CLOSED

Major changes in carbohydrate expression occur during the onset and progression of cancer. These alterations in glycosylation may result in both the loss of normal carbohydrate antigens (e.g. ABO blood group antigens) and/or high expression of carbohydrate structures that normally have low or restricted expression in healthy adults. The Tn antigen is expressed in most carcinomas, during embryogenesis, on pathogenic parasites, and on HIV, yet its expression is rare in normal adult tissue, creating a considerable interest in monitoring the expression of the Tn antigen for diagnostic purposes as well as for the development of Tn-based vaccines for cancer and HIV. The accurate detection of the Tn antigen is essential for both basic and applied research. However, monitoring the expression of this antigen is not trivial. Selective recognition of carbohydrate epitopes is challenging, especially for small epitopes such as the Tn antigen, and presently, there is no method nor approach providing an accurate and reliable information on the expression of this antigen. The goal of present proposal is to “evolve” the GafD lectin as a molecular probe to be used in the detection the Tn tumor biomarker and solve the problem of its recurrent inaccurate detection in cancer. Phage display technology will be used to modulate the properties of GafD throughout rounds of selection against different antigens, accumulating and refining its improvements in selectivity/affinity towards a finely tuned and specific Tn antigen binder. Subsequently, the identified receptor(s) will be expressed and fully characterized by an integrated multidisciplinary approach compressed of glycan microarrays, NMR; ITC; SPR and X-ray crystallography. The presented research will create a defined, precise and reliable tool for the evaluation of Tn expression, which will have great implications in the development of Tn-based diagnostics and vaccines.

Keywords: structural chemistry,biological engineering,molecular evolution,molecular markers and recognition,cancer diagnosis
Magnetization dynamics in anisotropic magnetic nanoparticles investigated using time-resolved X-ray and neutron scattering techniques (JANUS DYNAMICS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-05-01
End date: 2013-10-31
Duration (months): 18.0
Total project cost (EUR): 145196.1
EU funding (EUR): 145196.1
Participants: 1
Project status: CLOSED

The magnetization relaxation of nanosized magnetic objects plays an important role for their technological applicability. For applications in data storage, a large magnetic anisotropy is required in order to retain the magnetization state in the required relaxation time and temperature range. For application in the fields of magnetic imaging or magnetic hyperthermia, however, the electromagnetically induced relaxation of superparamagnetic nanoparticles is desired. Magnetization relaxation effects depend on the interplay of magnetic anisotropy and volume and are thus largely influenced by the nanoparticle composition, shape, interface effects, and interparticle interactions. In this project, we will quantitatively investigate the magnetization relaxation of magnetic nanoparticles and their assemblies. In particular, the effects of shape anisotropy, exchange bias, and magnetoelectric coupling in anisotropic nanoparticles will be explored. Janus nanoparticles, consisting of two epitaxially aligned hemispheres of different composition, allow for a controlled variation of anisotropic shape and interface effects in nanoparticles, and thus represent suitable model systems for the proposed study. Particular emphasis will be given to multifunctional Janus particles, combining e.g. magnetism and polarity with low dimensionality, which may potentially serve as building blocks for multifunctional nanomaterials. We will investigate the magnetization relaxation effects by application of advanced X-ray and neutron scattering techniques including stroboscopic small-angle scattering and nuclear resonant X-ray scattering. As a result, we expect to gain precise information on the influence of exchange bias, magnetoelectric coupling, and interparticle interactions on the Néel relaxation. This will improve the understanding of magnetization dynamics in anisotropic nanoparticles and may thus contribute to the exploration of further suitable nanomaterials for technological applications.

Keywords: electronic,magnetic and superconductive properties,solid state physics,neutron physics,nanotechnology
International Development Policies of the New Member States – Europeanization and Future Directions (INTDEPNEW)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-09-01
End date: 2013-08-31
Duration (months): 12.0
Total project cost (EUR): 104516.7
EU funding (EUR): 104516.7
Participants: 1
Project status: CLOSED

The applicant, Dr. Balazs Szent-Ivanyi works as a researcher at the Corvinus University in Budapest, Hungary. He earned his PhD in economics in 2010 and is an expert on international development policies and foreign aid. The host organisation is the School of Politics and International Studies (POLIS) at the University of Leeds, UK, with Dr. Simon Lightfoot supervising the activities of the fellow. The main aim of the fellowship is to help the applicant further his career in development studies, under the guidance of world renowned experts. The proposed research will concentrate on creating a better understanding of the emerging foreign aid policies of the Central and Eastern European countries and the effects membership in the European Union has on these policies. It will also provide the applicant with research training related to the methodology and concepts of development studies and political science, as well as in complementary skills like project management and academic leadership, thus enabling him to carry out and manage multidisciplinary research in the future. The knowledge and skills gained during the fellowship will greatly help the applicant in developing his career, and the results of the proposed research will have important implications for national and EU-level development policies.

Keywords: international development policy,foreign aid,emerging donors,central and eastern europe
Encapsulated Water Oxidation Catalysts (EWOCS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-03-19
End date: 2014-03-18
Duration (months): 24.0
Total project cost (EUR): 168896.4
EU funding (EUR): 168896.4
Participants: 1
Project status: CLOSED

Developing a sustainable global energy currency is considered to be one of, if not the, biggest challenge facing researchers today. Fuel cells and related technologies offer great promise however much work, particularly in methods for the efficient oxidative splitting of water, is still to be done before a suitable commercial solution is realised. This project aims to drive the field forward by developing new Encapsulated Water Oxidation Catalysts (EWOCs) with highly superior characteristics to the current state of the art heterogeneous systems. Through ligand design and functionalization, the active metal centers in these coordination complex catalysts will be encapsulated, either by enclosure of the primary coordinating ligand sphere or by extension of the ligand sphere with covalently grafted, oxidatively stable, dendrimer chains. Both approaches will increase intermolecular repulsions between the outer surfaces of the ligands, thus reducing undesired interactions between ligands and neighbouring catalyst active sites, subsequently minimising degradation, and increasing catalyst stability. The fellow’s experience in organic and inorganic synthesis, coupled with the host’s expertise in the synthesis, characterisation and evaluation of Ruthenium-based catalyst systems is an ideal pairing for achieving the tasks set out for the project: The fellow will synthesise the ligands, dendrimers and final target metal complexes, then assess their catalytic performance, paying particular attention to turnover frequency (TOF) and turnover number (TON) as a function of encapsulation. The host will provide close guidance for the fellow as well as the necessary training in the catalyst evaluation techniques. The proposal contains an innovative and competitive research project relevant on a global scale, as well as complementary training and personal development opportunities, providing the fellow with an excellent foundation from which to build his academic research career.

Keywords: solar chemistry,inorganic chemistry,reaction mechanisms and dynamics,macromolecular chemistry,catalysis,water oxidation,solar fuels