Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Flexible electrodes based on a zeolitic imidazolate framework and cellulose nanofibers composite: towards wearable energy storage (FLEXSTORE) (FLEXSTORE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium,Korea, Republic of
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-12-01
End date: 2026-11-30
Duration (months): 24.0
Total project cost (EUR): 191760.0
EU funding (EUR): 191760.0
Participants: 3
Project status: SIGNED

The progressive size diminution of electronic modules are undergoing bottlenecks in dwindling charge storage devices i.e., batteries and supercapacitors, constraining their development into wearable energy storage and flexible pollution free technologies. The inherent extended cycle life, rapid charge/discharge, and high power density of supercapacitors rank them superior over other energy storage systems. In modern market of zero-pollution energy devices, recently flexible and lightweight formula are trending to meet the current requirement of wearable energy storage. In this context, cellulose nanofiber (CNFs) incorporated zeolitic imidazole framework (ZIF) as hybridization have the potential to meet this demand, as they are core of active electrode materials for flexible supercapacitors and texturally tailored to demonstrate flexible/foldable properties. Thus, the exploration of the ZIF on CNF as a multifunctional hybrid material will provide high surface area and dispersion stability, while demonstrating superior analytical performance. FLEXSTOR will elucidate: 1) uniform distribution of ZIF nanocrystals on interface of CNF as conductive electrode 2) the rational design of polymer solid-state gel electrolyte in form of flexible solid-state supercapacitor and 3) the enhanced charge storage performance withstanding the mechanical deformation. With these perspectives, FLEXSTOR will introduce flexible and lightweight active compounds for wearable energy storage devices.

Keywords: supercapacitors,flexible solid state supercapacitors,triboelectric nanogenerators,organic inorganic hybrids,conductive electrodes,wearable energy storage devices
A SpinWave Ising Machine (SWIM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-07-01
End date: 2025-06-30
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 1
Project status: CLOSED

The SWIM project will tackle a critical challenge for the emerging field of Ising Machines (IMs): the development of miniaturized, low-power, and low-cost IMs with high computational power, commercial feasibility, and speed beyond classical Von-Neuman and CMOS-based solutions. SWIM will achieve this through exploiting exceptionally slow propagating spinwaves and using off-the-shelf power-efficient microwave electronic components and circuits in an entirely novel architecture of YIG-film-based Ising Machines (IM) with potential performance many orders of magnitude beyond the state-of-the-art. The project's objectives are to explore the possibilities of using spinwaves and microwave signals to construct multiphysical time-multiplexed IMs and study and determine the spinwave phenomena and electronic design techniques needed to improve targeted parameters: power consumption, Ising spin capacity, physical size, and speed performance. The objectives will be achieved through a multidisciplinary approach involving classical and modern methods. Theoretical magnetostatic description of propagating spinwaves, micromagnetic simulation methods, and electronic circuit design theory will be used for the SWIM design. Brillouin light scattering spectroscopy and microwave measurement techniques will be used for the analysis of the results and further improvement.

Keywords: ising machines,spinwaves,magnonics,computing,combinatorial optimization problems,oscillators
Artifying fibroblasts: Perturbation modelling in the lung tumor phase space to rewire fibroblasts for immunotherapy. (artFibro)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and I mmunotherapy
Panel description: The immune system , related disorders  and their mechanisms , biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases , innovative imm unological tools and approaches , including  therapies
Countries involved: Greece
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-04-01
End date: 2028-03-31
Duration (months): 60.0
Total project cost (EUR): 1997250.0
EU funding (EUR): 1997250.0
Participants: 1
Project status: SIGNED

Lung cancer is the leading cause of cancer death. Immunotherapy improved survival rates, but efficacy is limited to selected patients. We recently discovered universal antigen presenting fibroblasts (apFibros) across human and murine lung tumors and showed that they directly stimulate cancer-specific CD4 T cells, creating immunological hot spots that support immune rejection. These studies achieved a breakthrough on the role of in situ cancer antigen presentation and proposed a novel model whereby tumors can sustain T cells independently of lymph nodes. Preliminary data suggest that lung apFibros help overcome resistance to checkpoint inhibitors. For their immunotherapeutic exploitation of apFibros two bottlenecks must be overcome: low numbers and incomplete understanding of their configurations. We will integrate computational and laboratory experiments and work in parallel in human and mouse models to generate perturbation datasets across single-cell/cell systems, transcriptomics/epigenomics, spatial/temporal levels, and dissect the molecular landscape that regulates fibroblast states. Our ultimate goal is to unravel perturbations that can diverge cancer-associated fibroblasts to antigen presenting states. The following questions are at the core of our proposal i) how do diverse fibroblast states emerge and evolve? ii) which gene regulatory networks drive specificity of these states? ii) which are the functional modules that are driven by apFibros and how are they mechanistically explained? iv) how can we transdifferentiate existing fibroblasts to acquire antigen presenting states? v) how can fibroblast reprogramming help overcome immunotherapy resistance? The proposed research should help advance mechanistic concepts in what we term the “adaptive immune mesenchyme”, decode the complexity of peripheral antigen presentation in tumors and beyond and promote targeting of the stroma for immunotherapy.

Keywords: fibroblasts,mesenchyme,cancer antigens,transdifferentiation,cell reprogramming,immunotherapy,in vivo gene editing
Intermetallic Phase Heterostructured Circular Aluminium Alloys (HETEROCIRCAL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Austria
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-04-01
End date: 2029-03-31
Duration (months): 60.0
Total project cost (EUR): 1999989.0
EU funding (EUR): 1999989.0
Participants: 1
Project status: SIGNED

A tenet in metallurgy is that the purer metals and alloys are, the better are their properties. However, as recycling in material production increases in importance, so do impurity levels. In aluminium the consequences are particularly harmful because the solubility of most elements in aluminium is very small, resulting in the formation of brittle intermetallic phases. Moreover, once impurities have entered aluminium, it is nearly impossible to remove them. The HETEROCIRCAL project aims to break the paradigm of „harmful“ impurities. HETEROCIRCAL’s main contribution will be to develop a new, ground-breaking class of upcycled materials that can tolerate high levels of impurities. We will achieve this goal by designing intermetallic phase containing heterostructured alloys where previously detrimental intermetallic phases become impurity sinks – sinks which also form a novel heterostructure which features an excellent trade-off between strength and ductility. Here we aim to reverse the common view of primary intermetallic phases in aluminium wrought alloys, and to extend their admitted volume fraction to unexplored regions. Our preliminary work gives evidence that structures with such properties are in fact possible. The main challenge will be to develop viable means of creating beneficial intermetallic phase heterostructures, that are applicable in large-scale. We will address it by manipulating intermetallic phases during solidification and solid-state processing and applying a high-throughput method. HETEROCIRCAL’s aim is also to gain insights into the formation of intermetallic phases at high resolution and their role in the novel heterostructures. The project will meet the enormous challenge of creating sustainable aluminium alloys for a future circular economy, and reduce both the need to dilute alloys with pure aluminium produced from natural resources and the continuous downcycling of alloys. HETEROCIRCAL will also advance European metallurgy in general.
Causes and Consequences of Labor Market Flexibility (LABFLEX)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: Norway
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-12-01
End date: 2027-11-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Globalization and technological change have transformed the workplace and the organization of labor. At the core of these major developments is the degree of flexibility in the labor market. Alternative work arrangements, e.g., outsourcing, sub-contracting, flexible scheduling, and flexible pay jobs have become a common feature of labor markets across the globe. While most economists would argue that labor market flexibility facilitates reaping the benefits of globalization and technology growth, these developments can have far reaching consequences for the division of resources in society. Indeed, the recent decades have witnessed a sharp rise in wage inequality. LABFLEX is motivated by these developments and seeks to investigate the causes and consequences of labor market flexibility. LABFLEX raises a series of questions: Do differences in job contracts reflect shifts in worker preferences, or do they mirror advances in technology that facilitate gains from organizing job tasks differently? What are the impacts of flexibility in job contracts on wage inequality and gender wage gaps? Are workers being compensated for the adverse work conditions or the higher income risks, or do changes in job contracts reflect changes in the sharing of rents between workers and firms? How do labor market institutions affect flexibility? And what is the role of labor market policies? To answer these questions, LABFLEX will for the first-time link register data to large-scale experimental evidence on workers’ stated preferences for a wide array of work and pay arrangements, and an exhaustive full-text corpus of vacancies with information on job attributes. This will allow drawing a very detailed picture of both the supply and the demand side of the labor market, facilitating a study of flexibility in job contracts. Combining these data with experimental and structural methods, LABFLEX will provide new evidence on the causes and consequences of labor market flexibility.

Keywords: labor market flexibility,wage inequality,alternative work arrangements,performance pay,job contracts,compensating differentials,labor market institutions,search frictions
Mosquito-specific phagostimulants and pheromones for environment-friendly mosquito vector control (SemioMVC)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2023-12-01
End date: 2026-05-31
Duration (months): 30.0
Total project cost (EUR): 4171988.75
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Each year, chemicals worth €8bn are used for Mosquito Vector Control (MVC). Still, mosquito-borne diseases constitute a major socio-economic burden. As insecticides start losing efficacy and toxic chemicals are being banned from use (in the west in particular), we are becoming increasingly defenceless. By 2050, an additional 1bn people will be at risk of contracting at least one mosquito-borne disease due to the rapid expansion of habitats of mosquito vectors. Molecular Attraction is a pioneer in mosquito-specific phagostimulants and pheromones. We can control mosquito behaviour using minute quantities of highly effective, affordable and perfectly green semiochemicals. In the project, we will conduct a large-scale trial in sub-Saharan Africa to evaluate the efficacy, cost-effectiveness and environmental impact of our unique blends. The trial results will be leveraged to enter the global MVC market.

Keywords: mosquito borne diseases,pesticide free mosquito vector control,pheromones,malaria,phagostimulants,volatile organic compounds,semiochemicals
Magnetically enhanced electrocatalysis (MAGNESIS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Spain,Germany,Denmark
Call: ERC SYNERGY GRANTS (ERC-2025-SyG, 2025)
Start date: 2026-03-01
End date: 2032-02-29
Duration (months): 72.0
Total project cost (EUR): 12417798.0
EU funding (EUR): 12417798.0
Participants: 4
Project status: SIGNED

In the last years, electrochemistry and electrocatalysis are increasing their impact across several fields. A major driving force comes from the promise of substituting current fossil-fuel powered thermal methods in the industry by electrochemical alternatives, driven by renewable electricity. However, electrochemical methods are still far from reaching the desired target performance. In this landscape, the recent discovery of magnetic fields enhancing electrocatalytic processes offers a plausible new strategy. The idea of boosting an electrocatalytic reaction by an external magnetic field becomes highly persuasive. Still, the origin of this phenomenon is hardly understood, given its complexity: dealing with a magnetic field, in an electric field, on a dynamic surface, during a chemical reaction is a multiple-body problem. Our objective is to foster magneto-electrocatalysis by exploring rigorously the interplay between magnetic fields and electrocatalytic performance from atomic resolution in model systems up to full cell devices. This can only be achieved by a synergetic effort between experts in catalysis, surface science, magnetism and theory. We will focus on two relevant reactions: the spin-restricted water oxidation and the carbon dioxide reduction, both potentially spin-sensitive. Our aim is to validate the structural, electronic and magnetic key descriptors controlling this phenomenon, assessed by complementary ex-situ and operando data within the corresponding theoretical framework. Computational tools will consolidate the understanding and quantify the different mechanistic contributions to microscopic and macroscopic observations. The ambition with MAGNESIS is to define, in a rigorous way, the first principles and ultimate possibilities of magnetic fields in the development of advanced electrocatalytic methods, pioneering the novel field of magneto-electrochemical science & technology.

Keywords: magnetoelectrocatalysis,electrocatalysis,dft calculations,microscopy,multiscale modelling,magnetism,water electrolysis,water splitting,co2 utilisation
Adjacent to the Sea: How coastal communities resist and reimagine blue frontiers (AdjacenSEA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC CONSOLIDATOR GRANTS (ERC-2025-COG, 2025)
Start date: 2026-12-01
End date: 2031-11-30
Duration (months): 60.0
Total project cost (EUR): 2180476.0
EU funding (EUR): 2180476.0
Participants: 1
Project status: SIGNED

Background: Scholars have long grappled with the complexity of governing oceans and coasts, seeking to balance coastal inhabitants and seafaring nations with the dilemma: Who shall benefit from the sea? Privileging local, embedded coastal actors over global, mobile entities is central to the debate on adjacency; however, little conceptual innovation has addressed adjacency or how benefits are allocated. Objective: AdjacenSEA investigates the power of adjacency claims employed by coastal actors to assert their authority over area, access, and benefits (AAAB) of their seas and coasts. To achieve this, the project poses four research questions to address: articulations of adjacency, resistance logics within AAAB claims, discursive power of adjacency, and the potential of these to reimagine the position of local communities within marine governance. Approach: AdjacenSEA adopts an ambitious abductive research paradigm whereby its novel, synthesized theoretical framework of dimensions of adjacency, AAAB, and power will be evidenced through multi-site, comparative case studies. Case studies draw data from coastal communities navigating 1) tourism-driven gentrification, 2) offshore wind energy, and 3) blue carbon restoration. Data will be collected via mobile interviews and photovoice in addition to ethnographic fieldwork in three coastal regions. Using these innovative, participatory methods enables researchers to recognize the emplaced and embodied aspects of adjacency. Both thematic and discourse analyses will be used to answer the research questions. Impact: One of AdjacenSEA’s groundbreaking ambitions is to build a rich (qualitative) dataset and innovate the tradition of discourse analysis by taking it out from behind desk and into the field. AdjacenSEA will advance our understanding of whether coastal communities can mobilize adjacency and how these mobilizations enable or constrain sustainability transitions.

Keywords: marine social science,marine affairs,political ecology,blue economy,marine governance,coastal studies,maritime anthropology,coastal communities
Hyperpolarized sensors for probing metabolism in microfluidic organ-on-chip platforms (MicroHyperProbe)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,Israel
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-16
End date: 2025-03-15
Duration (months): 30.0
Total project cost (EUR): 206641.2
EU funding (EUR): 206641.2
Participants: 3
Project status: CLOSED

Hyperpolarized (HP) magnetic resonance imaging has emerged as a promising method for probing the biological characteristics of living tissue. A sensor molecule (e.g. pyruvate, fumarate, acetate) is hyperpolarized and injected into a patient, and the resulting metabolic flux can be used to assess cell viability, tumour response to therapy, and perform pH mapping, to name a few examples. Two significant barriers stand in the way of the widespread implementation of HP imaging: (1) the current hyperpolarization method, dissolution dynamic nuclear polarization (dDNP) is cumbersome, expensive, and requires expertise to operate the equipment, and; (2) preclinical method development relies heavily on the use of animal models which inhibits rapid screening of experiments. To overcome these limitations, in this project I will: (1) implement parahydrogen-induced polarization as the hyperpolarization method, which is significantly cheaper, easier to use, and can produce the hyperpolarized metabolites at a higher rate than dDNP, and; (2) perform the hyperpolarized imaging in organ-on-a-chip devices, which closely mimic in vivo conditions but allow for experiments to be performed at a greater rate, and can use human tissue as opposed to animal tissue to more closely mimic real conditions. The specific focus in this project will be to investigate whether HP metabolic imaging can provide insight into the progression of muscular dystrophy in human muscle tissue.

Keywords: microfluidics in vitro cell and tissue imaging
TRials supported by Smart Networks beyond 5G (TrialsNet)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Smart Networks and Services
Action type: Innovation actions
Partnership: SNS (JU-JTI)
Countries involved: Italy,Romania,United Kingdom,Spain,Greece,Belgium
Call: SNS Large Scale Trials and Pilots (LST&Ps) with Verticals (HORIZON-JU-SNS-2022, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 16740054.04
EU funding (EUR): 14587452.25
Participants: 30
Project status: SIGNED

TrialsNet will deploy full large-scale trials to implement a heterogenous and comprehensive set of innovative 6G applications based on various technologies such as cobots, metaverse, massive twinning, Internet of Senses, and covering three relevant domains of the urban ecosystems in Europe identified by i) Infrastructure, Transportation, Security & Safety, ii) eHealth & Emergency, and iii) Culture, Tourism & Entertainment. There will be 13 representative use cases developed over wide coverage areas with the involvement of extended sets of real users in 4 geographical clusters, in Italy, Spain, Greece and Romania. The use cases will be transversal, each single use case will be potentially implementable over different clusters, thus allowing for a holistic evaluation of the network KPIs. Targeting to improve the “liveability” of the urban environment in the different domains, TrialsNet will also pursue the objective to i) understand where current networks are not sufficient to assure the performance needed by the use cases, and to ii) derive the new requirements for next generation mobile networks. To achieve this, TrialsNet will design and deploy platforms and network solutions with advanced functionalities based on dynamic slicing management, E2E orchestration, NFV, MEC and AI/ML methods to be trialled on 3GPP and O-RAN network architectures. Design objectives of sustainability and affordability of the deployed systems will be also treated with the highest priority. Finally, TrialsNet will also develop appropriate technical assessment frameworks mapping quantitative and qualitative measures and visualizing the dynamics of the use cases for society acceptance. Proper KVIs will be monitored, proved and refined to provide a socio-technical vision towards early adoption of 6G solutions.

Keywords: large scale trials,beyond 5g,6g technology,e health,safety,culture,liveability,smart city