Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Two Paths of a Shared Past: Memory and Representation of the Nazi Genocide of Roma in Belarus and Lithuania (ROMPAST)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-07-01
End date: 2021-06-18
Duration (months): 24.0
Total project cost (EUR): 171460.8
EU funding (EUR): 171460.8
Participants: 1
Project status: CLOSED

The Romani communities of Belarus and Lithuania experienced World War II and the Nazi persecution in similar ways, such as deportations for forced labour, mass murder in the countryside and survival in Soviet partisan units. Throughout the Soviet era, Roma in the two countries faced the same challenges in their commemoration efforts, being denied a public recognition of their suffering. However, an oral history survey shows that there are also considerable differences between the memories of Belarusian and Lithuanian Roma. While Roma from Belarus emphasize their participation in the Soviet partisan units, describing it in the established Soviet patriotic vocabulary, Lithuanian Roma are more likely to underline their suffering and losses, as well as local complicity in their persecution. Why do the Romani minorities of two neighboring post-Soviet states make sense of their shared past so differently? This study suggests that the key to understanding this phenomenon lies in the socio-political context of memory work. Drawing on the post-Soviet transformations, official memory and minority politics in Belarus and Lithuania, this interdisciplinary research project compares the memory trajectories of Roma in these countries. It pays equal attention to the memories of “ordinary” Roma and Romani activists and the public representation of the Nazi genocide of Roma. Theoretically, this study seeks to understand how the processes of social exclusion and inclusion work at the level of memory and commemoration, and in what ways memory of the bitter past affects the identity of an ethnic group.

Keywords: romani histories,memory and identity of roma,nazi genocide of roma in belarus and lithuania,post soviet politics of memory,public representation,oral narratives,commemoration practices
Hospital Smart development based on AI (HosmartAI)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Spain,Germany,Italy,Italy,Spain,Spain,Germany,Ireland,Switzerland,Belgium,Switzerland,Greece,Slovenia,Belgium,Switzerland,Greece,Latvia,France,Netherlands,Luxembourg,United Kingdom,United Kingdom
Call: AI for the smart hospital of the future (H2020-DT-2020-1, 2020)
Start date: 2021-01-01
End date: 2024-05-31
Duration (months): 41.0
Total project cost (EUR): 11896352.5
EU funding (EUR): 9997244.0
Participants: 27
Project status: SIGNED

HosmartAI will create a common open Integration Platform with the necessary tools to facilitate and measure the benefits of integrating digital technologies (robotics and AI) in the healthcare system. A central hub will offer multi-faceted lasting functionalities (Marketplace, Co-creation space, Benchmarking) to healthcare stakeholders, combined with a collection of methods, tools and solutions to integrate and deploy AI-enabled solutions. The Benchmarking tool will promote the adoption in new settings, while enabling a meeting place for technology providers and end-users. Eight Large-Scale Pilots will implement and evaluate improvements in medical diagnosis, surgical interventions, prevention and treatment of diseases, and support for rehabilitation and long-term care in several Hospital and care settings. The project will target different medical aspects or manifestations such as Cancer (Pilot #1, #2 and #8); Gastrointestinal (GI) disorders (Pilot #1); Cardiovascular diseases (Pilot #1, #4, #5 and #7); Thoracic Disorders (Pilot #5); Neurological diseases (Pilot #3); Elderly Care and Neuropsychological Rehabilitation (Pilot #6); Fetal Growth Restriction (FGR) and Prematurity (Pilot #1). To ensure a user-centred approach, harmonization in the process (e.g. regarding ethical aspects, standardization, and robustness both from a technical and social and healthcare perspective), the living lab methodology will be employed. HosmartAI will identify the appropriate instruments (KPI) that measure efficiency without undermining access or quality of care. Liaison and co-operation activities with relevant stakeholders and open calls will enable ecosystem building and industrial clustering. HosmartAI brings together a consortium of leading organizations (3 large enterprises, 8 SMEs, 5 hospitals, 4 universities, 2 research centres and 2 associations) along with several more committed organizations (Letters of Support provided).

Keywords: diagnosis,treatment,assistive care,prevention,surgery,benchmarking,hospital,healthcare management,healthcare economics,healthcare platform
Efficacy and safety of low-dose IL-2 (ld-IL-2) as a Treg enhancer for anti-neuroinflammatory therapy in newly diagnosed Amyotrophic Lateral Sclerosis (ALS) patients (MIROCALS)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: Research and Innovation actions
Countries involved: Germany,Ireland,Italy,Sweden,France,France,France,France,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: New therapies for chronic non-communicable diseases (H2020-PHC-2014-two-stage, 2014)
Start date: 2015-09-01
End date: 2021-09-30
Duration (months): 73.0
Total project cost (EUR): 6510741.95
EU funding (EUR): 5980435.0
Participants: 15
Project status: CLOSED

Amyotrophic Lateral Sclerosis (ALS) is a fatal degenerative disorder of the brain and spinal cord affecting some 40,000 individuals in Europe, causing 11,000 deaths each year. Our pioneering work on riluzole showed that it is possible to modify ALS progression but all subsequent trials of potential neuroprotective agents have failed. Thus, drug development in ALS, including trial design, patient selection, and outcome measures must be re-engineered to break the current impasse. Nerve cell death in ALS is associated with inflammation, which contributes to cell damage, and is a logical target for therapy. Although therapeutic attempts to modify this have failed so far, the discovery of regulatory T cells (Tregs) as key players in controlling inflammatory processes opens new possibilities since defective Treg function is important in ALS. In fact, Treg numbers and function predict rates of disease progression and survival. Low-dose interleukin-2 (ld IL-2) safely and specifically increases and activates Tregs in conditions such as type 1 diabetes, HBc-vasculitis and chronic graft-versus-host disease, so ld IL-2 has the potential to significantly improve survival and deliver a therapeutic breakthrough in ALS. We also integrate biomarkers for nerve cell damage into the trial design to provide proof of concept/mechanism. “Modifying Immune Response and OutComes in ALS” (MIROCALS) will test the hypothesis that ld IL-2-induced increases in Tregs result in decreased rates of nerve cell damage and that this effect can be detected early in the course of the disease using a range of blood and cerebrospinal fluid biomarkers. Our ambition is to develop a new therapy for ALS and through this novel trial design break the impasse in drug development of other disease-modifying agents in ALS. The impact will be to enhance quality of life and care for people with ALS, and provide a robust model for Industry to encourage investment in ALS and other neurodegenerative diseases.

Keywords: amyotrophic lateral sclerosis,neurodegenerative disease,rct phase ii,proof of concept,proof of mechanism,low dose interleukin 2,regulatory t cells,anti inflammatory therapy
Maintenance of variation in aposematic colouration (MOVAC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2020-12-01
End date: 2024-04-29
Duration (months): 36.0
Total project cost (EUR): 319400.64
EU funding (EUR): 319400.64
Participants: 1
Project status: SIGNED

The research programme outlined in this proposal addresses a key question in evolutionary biology: how diversity in appearance is maintained under natural selection. In particular, I will investigate how colour pattern variation is maintained in species that exhibit warning coloration. This in an especially intriguing area of research because theory predicts that warning signals should look the same in colour and pattern so that they are more easily recognized and avoided by predators. I will investigate this topic using a charismatic polymorphic species of nudibranch mollusc that is common to the coasts of the United Kingdom. Nudibranchs are shell-less marine molluscs with an astounding array of colours and patterns, which they use to either hide from predators (camouflage) or to deter predators by warning them of nasty chemical defenses (warning signals). Nudibranchs are popular spectacles to divers and underwater photographers, yet the anti-predator coloration of this taxon is relatively under-explored. Therefore nudibranchs offer an especially exciting avenue for future research. In addition, research into the chemical defences of nudibranchs has led to the discovery of novel compounds with medicinal value, and the proposed research will contribute to our knowledge of the chemical ecology of these important species. The results of this research project will be used to inform and shape future theoretical models, which will be applicable to a range of ecological and evolutionary processes. The programme will draw attention to a fascinating and unique species, generating international interest and bringing new insight into Europe's coastal ecosystems.

Keywords: visual signals,warning signals,camouflage,anti predator colouration,sensory ecology,aposematism,predation,polymorphism,mollusc,opisthobranch,nudibranch,chemical ecology,chemical defense
Extensions of Temporal Representations for Ontology-based and Holistic Reasoning in the Mobile Quality of Life Domain (Onto-mQoL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: SIGNED

The concept of Quality of Life (QoL) involves several dimensions, such as physical health and psychological state, which can be assessed by mobile resources and integrated to support holistic processes of reasoning and interventions. Ontologies are the main approach to organise and integrate such data in the form of knowledge. However, while temporal aspects are usually present in the health domain, modelling information evolving time/events in ontologies is a complex problem since temporal relations are ternary and cannot be directly handled by ontology languages. This lack of expressiveness restricts the power of the reasoning processes because several time aspects, which are usually embedded in the QoL domain, cannot be employed. This project aims to design a conceptual framework for representation and reasoning about temporal aspects, associated with an ontological engineering method to guide the use of this novel framework during the process of converting static ontologies to their temporal versions. This approach will be used over the development of four case studies: (1) general QoL ontology to represent the data acquired by the Quality of Life technologies lab over its longitudinal mobile assessments; (2) specialization of the QoL ontology for the aging population; (3) use of the previous ontologies as background knowledge to support the generation of explanations for inductive reasoning; and (4) use of the previous ontologies for QoL deduction-based interventions. The validation of these ontologies and their applications will consider technical (identification of inconsistencies and contradiction) and empirical (ability to provide answers for competency questions) methods. As the main expected result, this project intends to deliver a pragmatic strategy to support the creation of knowledge-based resources that can in fact improve the QoL of the general public and be adapted to cover the particularities of specific population features.

Keywords: knowledge representation,mhealth,temporal logics,ontology,health assessment,health intervention
Leading the first data revolution in European agriculture: farm accountancy data and their impact 1870-1945 (datarev)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Austria,Switzerland
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 2
Project status: SIGNED

Long before Big Data invaded the countryside with datafication and High Precision Farming in the 2010s, at least another data-revolution had taken place in Europe. The spread of bookkeeping to ordinary farmers that started in the second half of the 19th century represents a revolutionary phenomenon whose importance and magnitude have been underestimated by historians. After overseas competition hit European farmers in the 1870s, the diffusion of bookkeeping techniques among ordinary European farmers was an important component of the recovery. The farm accountancy offices that mushroomed in northern and central Europe thanks to the work of economists and agricultural unions were crucial to reach medium and small farmers. Such offices acted as consulting agencies to farmers, helping them to be more efficient. But the offices also aggregated farm accountancy data from individual farms to produce benchmarks and for statistical purposes. Farmers unions could thus use micro-data to enlighten macro-economic issues and guide policy decisions at different levels in a striking example of “stakeholders’ statistics.” DATAREV investigates the diffusion of farm accountancy offices of continental Europe since the 1870s and the use of farm accountancy data by state and non-state actors in the first half of the 20th century. With its four subprojects, DATAREV thoroughly explores different aspect of the first data revolution, its actors and its consequences. It examines how economic and socially change was conceptualized and direct through accountancy data and statistics and how the peculiar structure of the agricultural business in Europe imposed constraints on bookkeeping unlike those at work in industry. It questions the agency in the datafication process and explores the conflicting claims to the data. Finally, it clarifies how farm accountancy data played a crucial role in the reorganization of the governance of European agriculture after the Long Depression.

Keywords: history and sociology of quantification,agricultural history,science and technology studies
Anamnesis: Post-Soviet Memory and Religion through the Prism of New Martyrs (ANAMNE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-01
End date: 2023-12-31
Duration (months): 24.0
Total project cost (EUR): 187572.48
EU funding (EUR): 187572.48
Participants: 1
Project status: CLOSED

The use of martyrdom narratives by religious institutions and believers in Eastern Europe to deal with the deaths of men and women who perished in communist purges and camps has attracted scholarly attention, but still lacks a comprehensive treatment. In particular, the mass canonisations and commemorations of so-called New Martyrs by the Orthodox churches suggest that religion has an important role to play in shaping narratives of the past and, thus, affecting collective identities. Yet, because works on post-communist non-secular memory are generally lacking, the role of East European churches in the process of coming to terms with the past remains poorly understood. The aim of ANAMNE is to provide a comparative, evidence-based study of Orthodox commemorations of New Martyrs in three national contexts, Russia, Ukraine and Estonia, with a special focus on gender, in particular on the lack of female New Martyrs. Using an interdisciplinary approach of memory studies, cultural history, anthropology and religious studies, this innovative study will provide insight into the relationship between the communist past and the collective identities of contemporary Orthodox Christians, and contribute to our understanding of the workings of martyrdom narratives globally. Expected outcomes of the study will be a change in the attitudes of the various stakeholders towards religion’s role in the process of ‘coming to terms with the past’. More broadly, the project will advance the excellence of comparative research on memory and religion in several Widening EU countries, a large majority of which have strong Orthodox representation. This MSCA fellowship in the Faculty of Religion and Theology at the Vrije Universiteit Amsterdam will allow the very Experienced Researcher to build strong leadership in her field, take the next step towards a research professorship, and strengthen her international networks and funding.

Keywords: post communist memory,orthodox church,martyrdom,the cult of saints,iconography,the relics,hagiography
The molecular basis of CULLIN E3 ligase regulation by the COP9 signalosome (CsnCRL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2014-ADG, 2014)
Start date: 2016-01-01
End date: 2021-02-28
Duration (months): 62.0
Total project cost (EUR): 2200677.0
EU funding (EUR): 2200677.0
Participants: 1
Project status: CLOSED

Specificity in the ubiquitin-proteasome system is largely conferred by ubiquitin E3 ligases (E3s). Cullin-RING ligases (CRLs), constituting ~30% of all E3s in humans, mediate the ubiquitination of ~20% of the proteins degraded by the proteasome. CRLs are divided into seven families based on their cullin constituent. Each cullin binds a RING domain protein, and a vast repertoire of adaptor/substrate receptor modules, collectively creating more than 200 distinct CRLs. All CRLs are regulated by the COP9 signalosome (CSN), an eight-protein isopeptidase that removes the covalently attached activator, NEDD8, from the cullin. Independent of NEDD8 cleavage, CSN forms protective complexes with CRLs, which prevents destructive auto-ubiquitination. The integrity of the CSN-CRL system is crucially important for the normal cell physiology. Based on our previous work on CRL structures (Fischer, et al., Nature 2014; Fischer, et al., Cell 2011) and that of isolated CSN (Lingaraju et al., Nature 2014), We now intend to provide the underlying molecular mechanism of CRL regulation by CSN. Structural insights at atomic resolution, combined with in vitro and in vivo functional studies are designed to reveal (i) how the signalosome deneddylates and maintains the bound ligases in an inactive state, (ii) how the multiple CSN subunits bind to structurally diverse CRLs, and (iii) how CSN is itself subject to regulation by post-translational modifications or additional further factors. The ERC funding would allow my lab to pursue an ambitious interdisciplinary approach combining X-ray crystallography, cryo-electron microscopy, biochemistry and cell biology. This is expected to provide a unique molecular understanding of CSN action. Beyond ubiquitination, insight into this >13- subunit CSN-CRL assembly will allow examining general principles of multi-subunit complex action and reveal how the numerous, often essential, subunits contribute to complex function.

Keywords: e3 ubiquitin ligase,signalosome,macromolecular complexes,molecular mechanism
VitiPrecision 2020 (VitiPrecision 2020)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Portugal
Call: Open Disruptive Innovation Scheme (implemented through the SME instrument) (H2020-SMEINST-1-2014, 2014)
Start date: 2015-06-01
End date: 2015-10-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The aim of the proposed project is to evaluate the development of a new and disruptive solution directed to Viticulture sector. In this project, ENERMETER intends to evaluate the market potential and execute a detailed technical and technological analysis to respond to some of the most pressing challenges of the actual market. The goal is to evaluate the potential of a solution the will represent a paradigm change in tools and technique to extract information about of vineyards cultures, important to the quality of the resulting product (wine). This innovation will allow manual processes start to be performed automatically and remotely, through a system of acquisition, image processing and analysis with high resolution of the entire area of the vineyard, based on the integration of computer vision and of inertial and georeferenced sensors coupled to a mobile system. With this project, ENERMETER aims to provide a set of novelties to the wine sector. This will be able to improve the quality of the final product, through a continuous monitoring of the production system, as well as reduce pollution of the environment due to rationalized use of pesticides. The entire solution is based on state of the art technology developed from scratch by ENERMETER, which enhances a high degree of customer satisfaction. The development of this project will allow the company to establish itself in the market as an innovative company whose investments reflect quality and robustness. The Viti Precision Solution is a multilingual, multicultural and multi-browser solution, offering all the necessary features to be implemented in the international market. ENERMETER already defined Australia, United States, Brazil and Chile as market target.

Keywords: precision viticulture,agriculture,artificial vision,image analyse and processing,vineyards georeferenced mapping