Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Augwind Integrated Renewable Battery System (AIRBattery)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499999.0
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Renewable energy sources like wind and solar are intermittent, leading to supply-demand mismatches that must be addressed to maintain grid stability. Efficient, long-duration energy storage solutions are essential for bridging these gaps, enabling the continuous delivery of clean energy and supporting European Union efforts to achieve net-zero carbon emissions by 2050. Augwind's AirBattery technology provides a revolutionary approach to energy storage. It utilizes an isothermal process and eliminates fossil-fuel dependency. AirBattery technology combines low-cost geological compressed air storage with highly efficient hydro power turbo machinery. This system's core innovation is its isothermal air compression, which dramatically reduces heat-related losses associated with traditional CAES, achieving a high round-trip efficiency (RTE) of over 60%. AirBattery's combination of highly efficient water pump turbomachinery and geological air storage, coupled with innovative isothermal processes, makes it a compelling solution for long-duration energy storage. The system uses 78% less water than traditional methods, costs 68% less, and has a smaller environmental footprint. This positions AirBattery as a vital technology in the renewable energy transition, providing a high-efficiency, fossil-fuel-free solution for long-term energy storage. Its design minimizes environmental impact, featuring a small above-ground footprint, no reliance on fossil fuels or rare-earth materials, and promoting local job creation through on-site manufacturing and resource procurement. Global grids face increasing electricity demand and higher renewable energy penetration, necessitating efficient, sustainable energy storage. AirBattery technology addresses these needs, with significant potential in the long-duration energy storage market, projected to grow to 1877 GWh by 2030. AirBattery’s innovative approach offers a crucial solution for achieving climate goals and energy resilience.

Keywords: renewable energy storage,compressed air energy storage caes,long duration energy storage,net zero emissions
Coating fruit and vegetables Reducing plastic waste and Increasing Shelf life of Produce (CRISP)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 3116343.23
EU funding (EUR): 2181440.26
Participants: 1
Project status: SIGNED

After harvest, it is difficult to maintain freshness of produce. An estimated 45% of fruit and vegetables go to waste every year. Currently, plastic packaging is the state-of-the-art to extend the shelf life of fruit and vegetables. However, plastic packaging waste is rarely recycled and is environmentally damaging; burning of plastics, leaching into groundwater from landfill and microplastic particles cause harm to the environment, and human health. Legislation in the EU is already addressing consumer concerns by restricting single use plastic packaging for fruits and vegetables. There is an urgent need from the fruit/vegetable sector for an alternative to plastic. Saveggy has developed an edible, biodegradable, plant-based coating for fruits and vegetables to reduce both food and packaging waste. It is the first and only alternative that offers a shelf life comparable to plastic packaging, and the only coating currently in development that is using 100% plant based, EFSA compliant food ingredients without any additives. The tasteless coating offers protection against dehydration, oxidation, mechanical damage, and microorganisms, extending the average shelf life of fruits and vegetables from 3-4 days to 10-14 days. Currently, Saveggy has developed and optimised a cucumber coating which will enter the market in 2024 (24 tonnes of coating). With EIC's support, we will 1) further develop formulations for other fruits and vegetables: bell pepper, banana, and eggplant, 2) develop coating application machinery, and 3) develop large-scale coating production. Our cucumber coating will be sold for €14-17/L (~€0.04-0.05/item compared to €0.02 for plastic). By 2026, we will reach breakeven point. The projected revenue for 2026 will be €14.1 M (973 tonnes of coating) with an EBITDA of €3.0 M. By 2030, revenue will reach €131.2 M (selling 6190 tonnes of coating and from out licensing) with an EBITDA of €86.6 M.

Keywords: coating,fruit,vegetables,packaging,plant based,edible,biodegradable,vegan,plastic waste reduction,shelf life increase,food waste reduction,food technology,sustainable
Illuminating new paths in heart failure therapy (HeartVision)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Norway,Spain,United Kingdom,Germany
Call: EIC Pathfinder Open (HORIZON-EIC-2025-PATHFINDEROPEN, 2025)
Start date: 2026-07-01
End date: 2030-06-30
Duration (months): 48.0
Total project cost (EUR): 3998796.25
EU funding (EUR): 3998796.25
Participants: 7
Project status: SIGNED

HeartVision is an ambitious high-risk, high-gain project that aims to unlock real-time, in vivo 3D microscopy of beating hearts and engineered heart tissues (EHTs) at cell-scale resolution – even deep within tissue folds. Heart failure is the leading cause of death worldwide, and today, there is no curative therapy for it. EHT transplantation offers hope, but we currently lack tools to assess its effectiveness in real time. Critical questions remain unanswered: Where do transplanted cardiomyocytes go? How do they integrate? When do they start contributing to heart function? Today, even imaging cells deep within therapy-scale EHTs is not possible - let alone in a beating heart. HeartVision will break this barrier by pushing optical microscopy into the infrared spectrum, enabling real-time, in vivo visualization of cardiomyocytes in both EHTs and beating hearts. This infrared microscopy window will be transformative - not just for heart failure therapy, but across regenerative medicine and disease research. HeartVision will deliver: + Vitroscope – a disruptive in vitro imaging tool for therapy-scale EHTs + Vivoscope – a radical in vivo imaging system for beating animal hearts + Computational tissue clearing – for deep structural and functional imaging + OrganLab – a high-value platform for next-gen therapy development These technologies will be used for: + Mitochondrial transfer studies for novel therapy pathways + Direct visualization of EHT integration in beating hearts HeartVision will generate multiple IPs with potential in current and future clinical and biotech markets, while ensuring open access to key scientific breakthroughs. It strikes a bold balance between innovation exploitation and open science dissemination. HeartVision will realize the dream of cell-scale imaging in living organs and put it in the hands of therapy developers, reshaping how we see, study, and treat heart failure and beyond.

Keywords: in vivo microscopy of live heart with cell scale resolution,computation clearing of biological tissue,therapy development and high throughput 3d imaging platform for engineered tissue
The mutual effect of levels of TRUst and REGulation over time: Analyzing ENergy regulation in the European Union (TRUREGEN)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Poland
Call: ERA Fellowships (HORIZON-WIDERA-2023-TALENTS-02, 2023)
Start date: 2025-01-06
End date: 2027-01-05
Duration (months): 24.0
Total project cost (EUR): 155793.6
EU funding (EUR): 155793.6
Participants: 1
Project status: SIGNED

Trust and regulation are key aspects that allow the advancement of the society. In setting regulations to govern the behavior of citizens, firms, states and policymakers adopt regulatory design choices that are partly grounded in trust between them and key actors in the field at hand. However, we do not know a lot when it comes to iterative processes through which trust and regulation affect each other over time. Through a combination of quantitative and qualitative methods, TRUREGEN aims to study the bidirectional relation between levels of trust and regulation. Focusing on the case of EU energy regulation during 2008-2022, the project 1) maps the nature of EU energy regulation along two key dimensions (specificity-broadness; stability-revisability), 2) assesses statistically significant relations between such a nature and current and past levels of trust/distrust among key EU and national actors (policymakers, regulators, regulatees, consumers, citizens), and 3) traces causal mechanisms underpinning these statistically significant relations. Expertise and facilities offered by the host (KU; Prof. Latusek), together with my existing experience and talent, mutually reinforce my development as independent researcher during the fellowship. In addition, advanced training (e.g. statistics, grant writing, science communication), two-way knowledge transfer allow me to realize my long-term career goals after the fellowship. A customized dissemination and communication plan will make the project and its results known well beyond the academic community, while also seeking active engagement with a wider audience (e.g. workshops, class experiments). Altogether, TRUREGEN at once bridges a major scientific gap, enhances my future career prospects, and makes a timely contribution to pressing societal debates.

Keywords: regulation,trust,energy regulation,european union
Online Data Intensive Solutions for Science in the Exabytes Era (ODISSEE)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Technology and infrastructures
Action type: Research and Innovation actions
Countries involved: France,Switzerland,United Kingdom,Netherlands,Spain,Norway,Germany,Israel
Call: R&D for the next generation of scientific instrumentation, tools, methods, solutions for RI upgrade (HORIZON-INFRA-2024-TECH-01, 2024)
Start date: 2025-01-01
End date: 2027-12-31
Duration (months): 36.0
Total project cost (EUR): 8253357.5
EU funding (EUR): 8253357.5
Participants: 17
Project status: SIGNED

This project federates efforts from 3 pan-European ESFRI infrastructures (HL-LHC, SKAO and SLICES-RI) in physical sciences, Big Data, and in the computing continuum supporting flagship instruments that will maintain and strengthen European leadership in high-energy physics and astronomy. The main goal is to enable key science projects, with the search for Dark Matter serving as a pilot program, combining the complementary capabilities of these three unique research infrastructures. ODISSEE will deliver evolutionary and revolutionary hardware and software platforms to address the corresponding digital challenges in a highly competitive international context. Developed through a joint and comprehensive R&D program with industry partners, as well as access to cutting edge experimental facilities from SLICES-RI, so as to enable HL-LHC and SKA to process and analyze the vast volumes of raw data they produce. Targeting such dataflow driven applications opens the way to a new range of technologies and services, feeding SLICES-RI with a unique yet representative set of specifications to progress their operational & experimental capacities at an unprecedented scale, increasing the dissemination potential. Bringing these 3 infrastructures to their full capacity, as well as operating and maintaining them, pose similar grand challenges across the digital continuum and require addressing the 3 dimensions of sustainability. Co-design and close partnership of academia with European companies will foster competitiveness of European industry and promote digital sovereignty. The project is deeply embedded into both regional and international R&I ecosystems, with strong connections to several major European initiatives and associated partnerships with main technology providers. Strong and lasting impact is built-in the two-fold exploitation strategy including the development of unique in-depth training for R.I. staff and extensive trans-sectoral dissemination.

Keywords: online ai methods,sustainable data intensive infrastructures,exascale cyber infrastructure,training for optimized operations
Molecular Insights into human NHE6: From Dimerization to Disease Implications (MIND-NHE6)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-11-01
End date: 2026-10-31
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 1
Project status: SIGNED

The human Na+/H+ exchanger 6 (HsNHE6) is crucial for regulating pH in recycling endosomes in the central nervous system. Mutations in HsNHE6 are linked to Christianson syndrome (CS), a severe neurodevelopmental disorder. However, the molecular mechanisms underlying HsNHE6 ion transport and its dysfunction due to CS mutations remain elusive. My research aims to bridge this knowledge gap by combining cellular and liposomal functional assays and single-particle cryo-electron microscopic structural investigations of HsNHE6. I will explore how dimerization in the lipid environment influences its ion transport mechanism, how the dimer functions as a whole, and how CS-associated mutations affect both dimerization and ion transport. I will conduct functional assays on heterodimeric HsNHE6, composed of wild-type (WT) and transport-deficient protomers, complemented by structural investigations to uncover the structure-function relationship during ion transport. I will identify HsNHE6-bound lipids and analyze HsNHE6 structure in its native environment utilizing detergent-free extraction. Furthermore, I will perform functional assessment in various lipid environments to unravel how the lipid environment influences dimerization and ion transport. Additionally, I aim to investigate whether and how CS-associated mutations lead to a loss-of-function phenotype and can exert a dominant-negative effect on a WT protomer by integrating functional assays with structural analyses of CS-mutant HsNHE6. The project aims to unravel the molecular mechanisms governing ion transport of HsNHE6 within the lipid bilayer and will provide insights into the molecular basis of CS. By integrating functional and structural data, it offers the potential to guide therapeutic targeting of HsNHE6 in the context of CS. The project is hosted at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, under the supervision of Assoc. Prof. Henriette E. Autzen.

Keywords: mammalian membrane protein,sodium hydrogen exchanger,single particle cryo em,native nanodiscs,christianson syndrome
Synaptic and neuron functionality in a single three terminal device leveraging the ferroionic control of the insulator-to-metal transition in a rare-earth-nickelates (SYNAPTRON)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 194074.56
EU funding (EUR): 194074.56
Participants: 2
Project status: SIGNED

Neuromorphic computing refers to the development of hardware that emulates the efficient way the brain processes information by exploiting the principles of parallelism, sparsity, and low power consumption. In the last decade, new device concepts and exotic materials have been explored to imitate the behaviour of neurons and synapses. However, demonstrations of the interaction between synaptic and neuron devices are very scarce, due to their different functional requirements and operating mechanisms. Moreover, to construct a fully functional neural network the individual artificial synapse and neuron devices are often integrated with transistors, capacitors, resistors and other peripheral circuits which greatly reduce the efficiency of the neuromorphic hardware. Therefore, a crucial step towards the practical integration of these systems in large-scale networks is to seamlessly integrate synaptic and neuronal functionalities using the same technology, preferably the same material and even (ideally) the same device. The unique electronic properties of strongly correlated oxides make them excellent candidates to face this challenge. The insulator-to-metal transitions in complex oxides can be tuned electronically in a non-volatile manner by several means, including ferroelectric effects, phase change transitions, valence variations, etc that can be used to demonstrate both neuron and synapse functionality. In this essence, this project SYANAPTRON aims at integrating neuron and synapse functionality in a single three-terminal nano-scale device, leveraging the co-existence and interplay of ferrionic (ferroelectricity and control of oxygen vacancies) and insulator-to-metal transitions in complex oxide heterostructures. The integration of synapse and neuron functionality in a single device is revolutionary as it will reduce the complex fabrication process, and peripheral circuitry, and enhance the packing density of future neuromorphic hardware systems.

Keywords: neuromorphic computing,insulator metal transition,negative differential resistance,ferroionics,correlated oxides
Longitudinal Investigation of Visual and Numerical Perception in Preterm and Full-term Infants (PrePER)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-06-19
End date: 2026-06-18
Duration (months): 24.0
Total project cost (EUR): 226751.04
EU funding (EUR): 226751.04
Participants: 1
Project status: SIGNED

The number of preterm births is on the rise -now more than 1 in 10 babies- and being born preterm is associated with having difficulties in two very important and related cognitive skills that we rely on daily: numerical and visual perception. However, a knowledge gap exists on neural and behavioural associations of numerical and visual perception in full-term and preterm infants. PrePER aims to uncover the underlying neural signatures of the cognitive dysfunctions that preterm infants might display in the first year of their lives and the role of parent-baby interaction to predict preterm infants that are at risk of developing these cognitive difficulties in the second year of their lives. The purpose is to establish criteria to identify infants (especially preterm) at-risk of having cognitive difficulties in numerical and visual perception. Shedding light on normal and impaired cognitive functions in infancy is an essential stepping stone that will pave the way for early diagnostic tools and interventions that would correct the cognitive dysfunctions more efficiently while the brain is still developing. The activities in PrePER will lead to original and innovative outcomes that are beneficial for four parties: 1) Scientific communities will be interested in the results as the ambitious research objectives address questions that have not been asked before. 2) Parents of preterm infants, health-care providers, and policy makers will be interested in the results as the overall aim is to establish criteria to identify infants at-risk of having cognitive-developmental difficulties in the first year of their lives. 3) The researcher will be accelerating her career progression as the training objectives meet her specific needs. 4) The supervisor will be enlarging her research interest and network as the research objectives include a topic within the researcher’s expertise.

Keywords: developmental neuroscience,neuropsychology,visual and numerical perception,preterm infants,eeg
Generalized nonextensive power-law transverse momentum spectra and their applications in high-energy collision physics (GLITTER)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Poland
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-04, 2022)
Start date: 2024-06-24
End date: 2026-06-23
Duration (months): 24.0
Total project cost (EUR): 155793.6
EU funding (EUR): 155793.6
Participants: 1
Project status: SIGNED

High energy collision events (proton-proton, lead-lead etc.) create the quark-gluon plasma (QGP), a state of matter in which the micro-second old universe existed. Distribution of particles created in these events help understand the properties of QGP. Experiments (e.g., the LHC at CERN) have given rise to many theoretical and phenomenological studies attempting to describe particle (hadron) production, which follows a power-law distribution, using statistical models. Hadron spectra generated in high-energy collisions are described by nonextensive distributions in the transverse momentum space represented by two parameters, the nonextensivity parameter q and temperature T. The nonextensive distributions approach the Boltzmann-Gibbs distributions in the limit q approaching 1. The nonextensive distributions, widely used in the phenomenological studies, can be calculated from statistical mechanics using constrained maximization of a generalized nonextensive entropy. The project GLITTER concentrates on these distributions and is divided into two parts: theory and phenomenology. In the theory part, the analytical form of the most generalized nonextensive transverse momentum spectra without an existing procedural arbitrariness will be calculated using nonextensive statistical mechanics for a simple harmonic oscillator. Also, a nonextensive model for an anisotropic medium will be proposed for arbitrary energy using the Mellin-Barnes representation. In the second part, phenomenological implications of these models will be explored using the ROOT programs that will be set up using the expertise of the supervisor's group. The project will propose analytical nonextensive models generalizing existing results and leading to reduced computation time. It will also clear the ambiguity regarding the usage of various forms of nonextensive distributions, will offer a firm basis for the studies in the field, and will generate many updated information about the properties of QGP.

Keywords: high energy collisions,quark gluon plasma,hadron transverse momentum spectra,nonextensive statistical mechanics