Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Microbial Resource Research Infrastructure - MIRRI (MIRRI)

Framework: FP7 — Capacities
Programme: Research Infrastructures
Destination: Support to new research infrastructures
Action type: Combination of CP & CSA
Countries involved: Germany,United Kingdom,France,Belgium,Netherlands,Sweden,Spain,Belgium,Germany,Portugal,Italy,Spain,Russian Federation,Poland,Italy
Call:  (FP7-INFRASTRUCTURES-2012-1-RTD, 2012)
Start date: 2012-11-01
End date: 2016-04-30
Duration (months): 42.0
Total project cost (EUR): 4121107.13
EU funding (EUR): 3137774.0
Participants: 16
Project status: CLOSED

MIRRI will be a pan-European distributed RI providing microbiological services, thus facilitating access to high quality microorganisms, their derivatives and associated data for research, development and application. It will connect resource holders with researchers and policy makers to deliver the resources and services more effectively and efficiently to meet the needs of innovation in biotechnology. The RI builds upon 60 microbial domain resource centres (BRCs) in 26 European countries; collectively they provide access to more than 350,000 strains of microorganisms. Microorganisms provide essential raw material for biotechnology - but to date less than 1% of the estimated number of species are described and available to be harnessed by man. As new species are discovered, expertise is difficult to locate to ensure correct identification. Public sequence databases provide modern tools for identification but the information is often of poor quality and often not backed up by the biological material to enable validation of data. The current fragmented resource distributed across Europe needs to be coordinated and operated to common standards with facilitating policy to help focus activities to the big challenges in healthcare, food security, poverty alleviation and climate change. Lacking infrastructure, policy framework and governance structures will be defined in the preparatory phase, as will be the links to researchers and policy makers. Specialist clusters will address priority issues and output steering. BRCs should be placed on national road maps, ensuring the pan-European strategy can be implemented. Cross discipline interactions with other RIs will lead to new approaches. Linking the microbial strain information to other relevant data will allow their full exploitation. Appropriate data mining solutions will enable focussing acquisition and delivery strategies, thus bridging current gaps and improving user access.

Keywords: facilitated and legitimate access,ex-situ living microbiological material,data,biomedicine,biotechnology,agriculture,research,application,environment,social impact,harnessing biodiversity
Evolution of stone tool hafting in the Palaeolithic (EVO-HAFT)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: The study of the human past
Countries involved: Belgium
Call:  (ERC-2012-StG_20111124, 2012)
Start date: 2013-01-01
End date: 2017-12-31
Duration (months): 60.0
Total project cost (EUR): 1192300.0
EU funding (EUR): 1192300.0
Participants: 1
Project status: CLOSED

Palaeolithic stone tool hafting has been considered important for decades, both in terms of technological and cognitive evolutions, but it has been hard to design methods that allow detailed insight into the appearance of hafting and its evolution through time. The main reason is that handles were manufactured from organic materials and these are only rarely preserved. The issue thus appears to largely escapes us, but as finds become more and more numerous, promising new techniques have also been developed, which allow a more detailed investigation of hafting. It has been demonstrated that a microscopic investigation of stone tools allows a distinction between tools that were used in the hand and those that were mounted in / on a handle, as well as an interpretation of the hafting arrangement. Knowing whether and how stone tools were hafted provides crucial data for improving our understanding of past human behaviour. It is invaluable for a better comprehension of technological evolutions, it provides insight into the organic tool component that is rarely preserved, and it allows understanding the complete life cycle of stone tools. The goal of this research project is to gain insights in the appearance, regional and chronological variability, and evolution of Palaeolithic stone tool hafting in Europe and the remaining Old World through a comprehensive functional investigation of key sites, which includes the analysis of wear traces and residues, bio/physico-chemical analyses, next to an elaborate experimental program. The proposed project starts from the conviction that many of the changes observed during the Palaeolithic can be understood based on functional data. Consequently, this research project will contribute significantly to our understanding of archaeological assemblages and their variability, and of past human behaviour and its evolution through time.

Keywords: palaeolithic,hunter-gatherers,stone tools,hafting wear,use-wear,residues
Dividing Powers among People(s): Towards a New Federal Theory for the 21st Century (NEO-FEDERALISM)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Institutions, values, beliefs and behaviour
Countries involved: United Kingdom
Call:  (ERC-2012-StG_20111124, 2012)
Start date: 2013-01-01
End date: 2017-08-31
Duration (months): 56.0
Total project cost (EUR): 909661.93
EU funding (EUR): 909661.93
Participants: 1
Project status: CLOSED

How should political power be divided within and among national peoples? Can the nineteenth-century theory of the sovereign and unitary State be applied to the social reality of the word of the twenty-first century? If not, what constitutional and philosophical theories can make sense of the empirical and normative world of our times? The rise of international organizations and, within Europe: the emergence of the European Union, have challenged the idea of the sovereign state ever since the end of the Second World War. And, in a seemingly paradoxical parallel, the myth of monolithic state power has equally come under attack from within states. Indeed: many modern states currently experience a political and constitutional devolution (Italy, Spain, United Kingdom). Can we identify these developments with federal theory? Federalism is a philosophical and a constitutional problem. The federal principle has made a long ‘journey through time in quest of a meaning’ (SR Davis). Modern federalism emerged with the rise of the European State system. And in the nineteenth century, the federal idea became reduced to the idea of the Federal State. In the light of this reductionism, international centralisation and regional decentralisation continue to be – largely – misunderstood by mainstream European legal scholarship. The proposed project would fill this gap by providing a comparative constitutional analysis of the federal principle. It will analyse the historical evolution of the principle from the eighteenth to the twenty century in the first part, and concentrate on three contemporary experiences of “dividing” or “sharing” sovereignty in the second. The three case studies of (neo)federalism in the 21st century correspond to three legal sphere: the international sphere (United Nations, World Trade Organisation), the supranational sphere (European Union, NAFTA), and the regional sphere (Spain, United Kingdom).

Keywords: federalism,division of powers,international organisations,devolution,constitutional history,comparative law,britain,united states,germany,spain,european union
Development of mouse mutant resources for functional analyses of human diseases - Enhancing the translation of research into innovation (INFRAFRONTIER-I3)

Framework: FP7 — Capacities
Programme: Research Infrastructures
Destination: Support to existing research infrastructures
Action type: Combination of CP & CSA
Countries involved: Germany,United Kingdom,Italy,France,United Kingdom,Greece,Sweden,Portugal,France,Spain,Spain,Finland,Germany,Germany,Denmark,Czechia,Austria,Canada,Israel,Netherlands,Belgium,Germany
Call:  (FP7-INFRASTRUCTURES-2012-1-RTD, 2012)
Start date: 2013-01-01
End date: 2016-12-31
Duration (months): 48.0
Total project cost (EUR): 12431663.54
EU funding (EUR): 9900000.0
Participants: 24
Project status: CLOSED

The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to: • Develop a series of mutant alleles for every gene in the mouse genome • Determine the phenotypic consequences of each mutation • Identify mouse models for the complete disease spectrum in humans To further develop and exploit the emerging mouse mutant resource, mouse models must be preserved and made available to the European biomedical research community. To this effect, the Infrafrontier-I3 project brings together the leading European centers for systemic phenotyping of mouse mutants and the European Mouse Mutant Archive network. The Infafrontier-I3 partners aim to meet the future challenges presented by phenotyping, archiving and disseminating mouse models in the ERA as follows: • Contribute to resource development by archiving of 1215 new mouse mutant lines • Provide free of charge Transnational Access to mouse production and 1st line phenotyping capacities • Offer a specialized axenic service to produce, maintain and to distribute germ-free mice • Provide user friendly accession of Infrafrontier services, extensive manual data curation and cross referencing with other mouse database • Improve user services by developing novel phenotyping and cryopreservation SOPs and by refining innovative research instrumentation • Engage with the user community using a wide range of PR activities, a dedicated user meeting and an industry liaison workshop • Offer state of the art cryopreservation and phenotyping training courses • Benchmark Infrafrontier services with other major repositories The comprehensive physical and data resources that will be generated by Infrafrontier-I3 will contribute to link basic biomedical research to medical applications and thereby drive innovation and support the Europe 2020 Strategy.

Keywords: mouse clinic,1st line phenotyping,cryopreservation,mouse as model of human disease,gnotobiology,bioinformatics
Global ATM security management (GAMMA)

Framework: FP7 — Cooperation
Programme: Security
Destination: Increasing the Security of infrastructures and utilities
Action type: Collaborative project
Countries involved: Italy,France,Spain,United Kingdom,France,Germany,Slovakia,France,France,Netherlands,Romania
Call:  (FP7-SEC-2012-1, 2012)
Start date: 2013-09-01
End date: 2017-11-30
Duration (months): 51.0
Total project cost (EUR): 14511482.92
EU funding (EUR): 9124760.0
Participants: 22
Project status: CLOSED

The GAMMA project stems from the recognition that while the SESAR initiative is effectively addressing some security issues in the new global ATM scenarios, there is a need to extend this scope to ensure a comprehensive assessment of the full set of security threats and vulnerabilities affecting ATM, considered as a system of systems and covering operational as well as technological aspects. In addition, there is a need, not completely met by SESAR, to establish a comprehensive framework for managing ATM security once SESAR deployment is engaged to minimise the effects of ATM crises brought about by security incidents. The GAMMA vision is to adopt a holistic approach for assessing ATM security, maintaining alignment with SESAR and reaching the following main objectives: - Extend the scope of threat assessment performed within SESAR to a more comprehensive system of systems level, inclusive of all ATM assets and all forms of threats. - Develop a Global ATM Security Management framework, representing a concrete proposal for the day-to-day operation of ATM Security and the management of crises at European level. - Define the architecture of an ATM security solution, suitable to support the security management of the global ATM system. - Design and implement prototype components of the ATM solution so as to demonstrate the functionalities and operations proposed for the future European ATM. - Set up a realistic validation environment, representative of the target ATM solution, through which to perform validation exercises aimed at validating the feasibility and assessing the adequateness of the procedures, technologies, and human resources issues proposed. GAMMA is strongly driven by the End Users present in the consortium supporting the project activities from the threat and vulnerability analysis to the validation of the developed concepts. The international dimension will also be considered with special reference to interoperability with US systems.

Keywords: security,threats
Updating the mind: The mechanisms behind behavioural change (UTM)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: The Human Mind and its complexity
Countries involved: United Kingdom
Call:  (ERC-2012-StG_20111124, 2012)
Start date: 2013-02-01
End date: 2018-01-31
Duration (months): 60.0
Total project cost (EUR): 1138518.0
EU funding (EUR): 1138518.0
Participants: 2
Project status: CLOSED

Translation of basic research on human executive control into facilitating behavioural change is a holy grail for psychologists and neuroscientists. Adaptive behaviour is attributed to executive functions that update the cognitive system. But how system updating mechanisms regulate behavioural change is still unclear. This stems from a lack of careful process analysis and a failure to integrate findings from different research areas. My proposal consists of three innovative subprojects. In the first subproject, I aim to develop a unified account of system updating and behavioural change. I propose that three well-defined cognitive processes (detection-selection-implementation) underlie all forms of updating; each component may be influenced by preparation or practice. In the second subproject, I aim to show how stress and incentives, which influence behavioural change outside the lab, modulate the updating processes studied in Subproject 1. This will lead to much richer models of updating and control. Finally, the third subproject will focus on the role of rules in system updating. More specifically, I will examine how both children and adults acquire new rules and how a rule-based control network can develop and strengthen. This may also provide a framework for the development of treatments. In each subproject, I will use carefully designed behavioural paradigms and integrate techniques such as neurostimulation, EEG, and mathematical modelling of decision-making to specify how updating occurs and how variation in the effectiveness of updating arises. The proposed work will substantially extend my previous work on response inhibition and executive control. I will synthesise work in cognitive, clinical, and social psychology, cognitive neuroscience, and neurobiology; and by providing novel important insights into the substrates of the executive control of updating, contribute to a better understanding of the many disorders associated with control deficits, and of human behaviour in general.

Keywords: executive control,system updating,behavioural change,preparatory control,associative learning,brain stimulation,eeg,stress,incentive motivation,addiction,eating disorders
Infrastructure for Systems Biology - Europe (ISBE)

Framework: FP7 — Capacities
Programme: Research Infrastructures
Destination: Support to new research infrastructures
Action type: Combination of CP & CSA
Countries involved: United Kingdom,Netherlands,Greece,Ireland,Germany,Finland,Germany,Norway,Czechia,Spain,Slovenia,Germany,Sweden,Netherlands,Netherlands,United Kingdom
Call:  (FP7-INFRASTRUCTURES-2012-1-RTD, 2012)
Start date: 2012-08-01
End date: 2015-07-31
Duration (months): 36.0
Total project cost (EUR): 6557213.2
EU funding (EUR): 4745718.13
Participants: 23
Project status: CLOSED

The Infrastructure for Systems Biology in Europe (ISBE) programme comprises an infrastructure that is designed to meet the needs of European systems biology, in terms of development, applications and training. In order to address this requirement, we are proposing a distributed, interconnected infrastructure which primarily comprises three types of centres: Data Integration Centres (DICs), and systems biology dedicated Data Generation Centres (DGCs), and Data Stewardship Centres (DSCs). DICs are research centres that apply and develop expertise in model-driven data integration and make this expertise available to the community. DGCs are technology-based centres that make available a wide range of high, medium and low throughput technologies that are essential for the acquisition of quantitative datasets under standardised conditions. DSCs are centres that are responsible for data processing, curation and analysis – they store data, models and simulations. Each type of centre will be functionally different, but organisationally similar. Within participating universities and other organisations across Europe there will be foci of expertise and facilities which fit the requirements for a DIC, DGC or DSC. Such foci will be evaluated and then designated as local centres of a particular type. Each focus will then form a component of a particular type of DIC, DGC or DSC centre. ISBE centres may be single institutions or can be distributed. Large institutions, such as leading universities, may well contribute facilities and expertise across different types of centres. A particular distributed centre may focus on an area of Systems Biology; for example, a model organism, a disease, or, alternatively an area such as biotechnology, ecology or green biology. Importantly, the ISBE will include technological expertise; for example, stochastic computation, algorithmic modelling, multi-scale modelling integration of diverse high-and low-throughput datasets.

Keywords: systems biology,infrastructure,technology,modelling,genomics,proteomics,metabolomics,database,ontologies,repository
Systemic Risk and Financial Vulnerabilities: Diagnosis and Solutions (SOLSYS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Individuals, institutions and markets
Countries involved: France
Call:  (ERC-2012-StG_20111124, 2012)
Start date: 2012-10-01
End date: 2017-09-30
Duration (months): 60.0
Total project cost (EUR): 1117200.0
EU funding (EUR): 1117200.0
Participants: 1
Project status: CLOSED

The general purpose of this research proposal is to improve our scientific understanding of the risk-taking of financial intermediaries, the sources and structure of systemic risk and to investigate new directions regarding risk measurement and optimal regulation of the financial sector. When financial institutions experience negative shocks, they can contaminate each-other. The amplification of initial shocks can spiral into a threat to the solvency of the entire financial system: this is systemic risk. Such contagion between financial intermediaries stems from several kinds of linkages and incentive structures which the proposal investigates. The understanding, measurement and anticipation of financial fragility has been high on financial regulators' priority list since the 2008 collapse of Lehman Brothers and has been revived further by the European sovereign risk. The research to be initiated under this proposal will mix intimately theoretical work and micro-empirical work. It will try to both increase our understanding of the financial crisis by opening the “black-box” of financial institutions and to directly touch in a concrete and forward-looking manner upon regulatory issues. The proposal articulates a research program around five main independent projects. Each project combines modeling and empirical tests and is intended to lead to a series of separate academic papers and policy implications. Project 1: Bank Vulnerability and Fire-Sales Spirals Project 2: Risk-Shifting, Systemic Risk and Monetary Policy Project 3: The Source and Dynamics of Rents in the Financial Industry Project 4: Regulating through Information: What Level of Transparency is Optimal? Project 5: Inequality, Political Economy and Financial Instability

Keywords: systemic risk,financial stability,financial regulation
The Carceral Archipelago: transnational circulations in global perspective, 1415-1960 (CARCHIPELAGO)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: The study of the human past
Countries involved: United Kingdom
Call:  (ERC-2012-StG_20111124, 2012)
Start date: 2013-03-01
End date: 2018-08-31
Duration (months): 66.0
Total project cost (EUR): 1492870.0
EU funding (EUR): 1492870.0
Participants: 1
Project status: CLOSED

This project centres ‘the carceral archipelago’ in the history of the making of the modern world. It analyses the relationships and circulations between and across convict transportation, penal colonies and labour, migration, coercion and confinement. It incorporates all the global powers engaged in transportation for the purpose of expansion and colonization - Europe, Russia, Latin America, China, Japan – over the period from Portugal’s first use of convicts in North Africa in 1415 to the dissolution of Stalin’s gulags in 1960. It uses an innovative theoretical base to shift convict transportation out of the history of crime and punishment into the new questions being raised by global and postcolonial history. The project maps for the first time global networks of transportation and penal colonies. It undertakes case study archival research on relatively unexplored convict flows, and on the mobility of ideas and practices around transportation and other modes of confinement. It analyses its findings within the broader literature, including on transportation but also debates around the definition of freedom/ unfreedom, the importance of circulating labour, and global divergence and convergence. It redefines what we mean by ‘transportation,’ explores penal transportation as an engine of global change, de-centres Europe in historical analysis, and defines long-term impacts on economy, society and identity. It places special stress on investigating whether a transnational approach to the topic gives us a fresh theoretical starting point for studying global history that moves beyond ‘nation’ or ‘empire.’ The project lies at the intersections of national, colonial and global history, and economic, social and cultural history. It will be of wide interest to scholars of labour, migration, punishment and confinement; comparative and global history; diaspora, creolization and cultural translation; and museum and heritage studies.