Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Single metal nanoparticles as molecular sensors (SINGLESENS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Physical and Analytical Chemical sciences
Countries involved: Germany
Call:  (ERC-2010-StG_20091028, 2010)
Start date: 2011-01-01
End date: 2015-12-31
Duration (months): 60.0
Total project cost (EUR): 1510000.0
EU funding (EUR): 1510000.0
Participants: 1
Project status: CLOSED

Optical spectroscopy of single plasmonic nanoparticles (NPs) has evolved into a recognized tool for nanoscopic sensing applications, using the sensitivity to the NP's environment,charge, size, shape, and proximity to other NPs. Here, I propose taking advantage of the nanoparticle s minuscule size approaching molecular dimensions in novel ways. Single particle plasmon sensors are in many ways the smallest possible giving unprecedented access to molecular events. The small size amplifies fluctuations by molecular events, allows massive parallel detection of analytes within tiny devices, and to monitor single nanoparticle formation and electrochemical surface reactions in real time. The objective of this project is therefore to develop and explore single-particle plasmon spectroscopy as a novel tool to study such molecular processes. The objective will be reached by (1) building three new setups progressing far beyond current technology and increasing time resolution, spectral sensitivity, and parallelization capability many orders of magnitude, (2) synthesizing nanoparticles with optimal plasmon sensing properties, and (3) simulating plasmon properties to guide the experiments and understand the physics behind the observed phenomena. The single-particle plasmon spectroscopy technique will be applied in four scientific directions to demonstrate its potential: (4) analyzing distance fluctuations of particle pairs linked by (bio-)polymers, (5) recording coverage fluctuations of biomolecules bound to nanoparticles, (6) demonstrating parallel detection of many analytes in multiplexed microfluidic devices, and (7) following particle formation and chemical reactions in a single particle reactor . Single-particle plasmon spectroscopy has the potential to provide a revolutionary new tool to study molecular processes and to become a major commercial analytical tool, especially for pharmaceutical research and development.

Keywords: plasmon,gold nanoparticle,single molecule,microscopy
Electronic transitions and bistability: states, switches, transitions and dynamics studied with high-resolution X-ray spectroscopy (X-CITED!)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Starting grants
Action type: Support for frontier research (ERC)
Panel: Condensed matter physics
Countries involved: Hungary
Call:  (ERC-2010-StG_20091028, 2010)
Start date: 2010-12-01
End date: 2015-11-30
Duration (months): 60.0
Total project cost (EUR): 1125960.0
EU funding (EUR): 1125960.0
Participants: 2
Project status: CLOSED

We propose to study transition metal compounds of uncommon transport properties and excitation characteristics applying emerging high-resolution X-ray spectroscopy. The objective is to determine the microscopic origin of the unconventional behaviour of systems with strong electron correlation through systematic investigations, as well as to reveal bistability conditions and excitation characteristics of switchable molecular systems. The main techniques involved are synchrotron radiation (SR)-based spectroscopies, which can explore the fine details of the electronic structure. Besides using existing end stations of SR facilities, we plan to build a portable spectrometer that can be advantageously used both in a laboratory (e.g., with a radioactive source) and at specially dedicated beamlines of SR facilities, in order to benefit from their specializations in extreme conditions and advanced sample environments, in particular unconventional experiments. This spectrometer should also be able to work in a time-resolved mode so that it could address the dynamics of electronic excitations on the attosecond to nanosecond time scale. The suggested work is expected to push high-resolution X-ray spectroscopies toward maturity, which should open up new horizons in electronic structure and dynamics studies of condensed matter research.

Keywords: the title is full of keywords
New approaches for the targeted therapy of Non-Small Cell Lung Cancer (LUNGTARGET)

Framework: FP7 — Cooperation
Programme: Health
Destination: Translating research for human health
Action type: Collaborative project
Countries involved: Belgium,United Kingdom,Spain,Germany,Switzerland,Israel,Hungary,Germany
Call:  (FP7-HEALTH-2010-two-stage, 2010)
Start date: 2011-01-01
End date: 2015-06-30
Duration (months): 54.0
Total project cost (EUR): 4067435.47
EU funding (EUR): 2997332.0
Participants: 10
Project status: CLOSED

Lung cancer is the most common cancer fatality in Europe (335000 deaths/yr). Non-small cell lung cancer (NSCLC) consists 85% of the cases, with 5 yr survival <15%. Hence, this proposal focuses on the urgent need for better NSCLC therapies. This is a European problem at societal and scientific level: better therapies are needed to keep the spiralling costs of European health systems under control, and the required expertise (basic science, clinical, biotech, experimental therapeutics) is scattered over the EU. Because of the diversity of the NSCLC problem (and the small/medium size of the project) we are focusing on two particular problems: 1) to find solutions for the currently clinically observed resistance problems with epidermal growth factor receptor (EGFR) targeting therapies (10% of NSCLC patients), and 2) to find a solution for the clinically unmet need for NSCLC patients with KRAS mutations (30% of NSCLC), for whom there virtually is no cure (besides very modest effects of platinum based therapies). Based on this focus, we assembled an EU wide consortium which joins excellent expertise at both the basic science (EGFR family, KRAS), clinical (involvement of several clinical study leaders) and biotech level (involvement of academic and SME biotech component). We aim: 1) To identify novel drug targets for the improvement of EGFR targeting therapies and for the development of therapies for K-Ras mutant patients (via genome wide RNAi screening and kinome/secretome profiling). 2) To validate these targets in innovative mouse models that replicate the clinical problem, and in patient materials (tissue and serum) 3) To develop novel therapeutics based on the unique expertise of our partners: anti-receptor DARPins (designed ankyrin repeat proteins), monoclonals or soluble receptors targeting the BROADER EGFR family (to block compensatory signalling), and protein kinase inhibitors The results will have important basic scientific, clinical and economic impact

Keywords: lung cancer,targeted therapy,growth factors,rnai,antibodies,signal transduction,oncology
Photopolymer based customized additive manufacturing technologies (PHOCAM)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: New production
Action type: Collaborative project
Countries involved: Austria,Finland,Germany,Germany,Austria,Austria,Norway
Call:  (FP7-2010-NMP-ICT-FoF, 2010)
Start date: 2010-06-01
End date: 2013-05-31
Duration (months): 36.0
Total project cost (EUR): 3609446.6
EU funding (EUR): 2455362.0
Participants: 7
Project status: CLOSED

Lithography based additive manufacturing technologies (AMT) are capable of fabricating parts with excellent surface quality, good feature resolution and precision. With recent developments in the field of ultra-short-pulse lasers and light engines based on light emitting diodes, robust and economical light sources have become available. This project aims at developing integrated lithography-based additive manufacturing systems which will, for the first time, facilitate the processing of photopolymer-based materials for the factory of the future. The focus of the project is to unite industrial know-how in the field of supply chain management, software development, photopolymers and ceramics, high-performance light-sources, system integration and end-users in order to provide a fully integrated process chain at the end of the project. The consortium will rely on two core-technologies: (1) Digital light processing (DLP) based processes will be used to process ceramic-filled photopolymers, leading to fully dense ceramic parts at the end of the process chain. (2) Two photon polymerization (2PP) will be used to fabricate high-resolution structures with features in the range of 100-200nm. Both processes will be tuned to reduce system cost, and significantly increase throughput and reliability at the same time. Goal is to deliver &apos;first-time-right&apos; strategies for the involved end-users. This necessitates the development of supply chains with integrated quality sensors. Targeted applications include thread guides for textile machinery, ceramic moulds for the fabrication of high-performance turbine blades and microstructures for computer tomography equipment.

Keywords: supply chain management,rapid manufacturing,photopolymers,ceramics,two photon polymerization
Plug and Produce Joint Interface Modules (POPJIM)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: New production
Action type: Collaborative project
Countries involved: Sweden,Spain,Poland,Austria,Germany,France,Netherlands
Call:  (FP7-2010-NMP-ICT-FoF, 2010)
Start date: 2010-09-01
End date: 2014-08-31
Duration (months): 48.0
Total project cost (EUR): 4436908.0
EU funding (EUR): 3285624.0
Participants: 10
Project status: CLOSED

PoPJIM identifies critical performance limiting problems in machine tool design and use. The project idea is based on two crucial innovative solutions: i) replacing conventional machine tool structural joint interfaces by a self configuring and optimising mechatronic module called Joint Interface Module, JIM, made of functional materials and ii) a wireless network consisting of these modules and a machining process proxy to enable adaptive control and plug and produce capability to the JIMs. JIMs are designed to adapt the dynamic behaviour of a machine-tool during its interaction with the cutting process. Traditionally dynamic instability in a machining process is controlled by tuning the process parameters to match with the inherent dynamic characteristics of the machine tool structure which often results in lowering the rates of production. The novelty of the JIM concept is instead of changing the process parameters; dynamic stiffness of the machine tool is controlled to maintain the process stability. The Distributed Wireless Configuration and Control Network enables plug and produce capability and decentralised control of JIMs through a wireless communication network. This development is essential for achieving modularity and plug and produce capability for JIM-based machine tools. Controlled design of JIMs allows the dynamic behaviour of the machine tool to be predictable with more accuracy. The mechatronic design of the JIM includes an integrated control system and embedded intelligence which enable to be self-adaptive for optimising the dynamic stiffness within its design range during a machining process. The results of research and development work will be demonstrated in industrial context and there is a dissemination and exploitation activity to reach out potential stakeholders.

Keywords: joint interface modules,machine tools,dynamic stiffness,wirelss netwrok,functional materials
Efficient and Precise 3D Integration of Heterogeneous Microsystems from Fabrication to Assembly (FAB2ASM)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: New production
Action type: Collaborative project
Countries involved: Finland,France,Switzerland,Belgium,Netherlands,Italy,Netherlands,France,France
Call:  (FP7-2010-NMP-ICT-FoF, 2010)
Start date: 2010-05-01
End date: 2013-04-30
Duration (months): 36.0
Total project cost (EUR): 7053327.84
EU funding (EUR): 4733600.0
Participants: 10
Project status: CLOSED

FAB2ASM tackles a major problem in 3D integration that currently limits industrial take-up: high throughput and high accuracy 3D integration of miniaturized dies onto dies or substrates. This issue is extremely important for 3D integration of microelectronics and microsystems. 3D integration will take off in the next 5 years in all measures including total number of devices, the market share, as well as the density of the connections. The state-of-the-art integration technology for 3D microsystems relies on robotic pick-and-placing machines and machine vision, which cannot achieve simultaneously high-speed and high-precision. If high precision e.g. a micron is needed, either the cycle time of integration can be very long, from e.g. over ten seconds to minutes, or even not achievable. The objective of the FAB2ASM is to develop highly efficient and precise die-level component integration technology based on hybrid assembly technology that joins robotic tools and self-alignment and corresponding interfacing methods for multi-functional microsystems. In contrast to most explorative self-assembly technology developed to-date, FAB2ASM attempts to develop a highly industry relevant technology that reuses most of the industrial process steps, but on the other hand dramatically improves the performance of the integration process in the precision and efficiency chart. FAB2ASM will allow handling small (100 µm) and/or thin dies (20 µm), ultra high speed assembly (40,000 UPH), and flip-chip capabilities, while ensuring industry proven reliability. Led by AALTO, this consortium of 5 research centers and 4 industries (ST, NXP, BX, 3DPLUS) will join force to fulfil this urgent and important need of industry in 3D integration, and will demonstrate the merits in three industry led demonstrators: one manufacturing equipment demonstrator, one photonic IC demonstrator and 3D microelectronics demonstrator.

Keywords: 3d integration,die-to-wafer,die-to-die,self-assembly,microassembly,hybrid assembly
School of the Future – Towards Zero Emission with High Performance Indoor Environment (SCHOOL OF THE FUTURE)

Framework: FP7 — Cooperation
Programme: Energy
Destination: Energy efficiency and savings
Action type: Collaborative project
Countries involved: Germany,Italy,Denmark,Norway,Denmark,Denmark,Germany,Denmark
Call:  (FP7-2010-NMP-ENV-ENERGY-ICT-EeB, 2010)
Start date: 2011-02-01
End date: 2016-01-31
Duration (months): 60.0
Total project cost (EUR): 4974936.0
EU funding (EUR): 3473360.0
Participants: 14
Project status: CLOSED

The aim of the “School of the Future” project is to design, demonstrate, evaluate and communicate shining examples of how to reach the future high performance building level. School buildings and their primary users pupils - the next generations - are in the focus of the project. Both, the energy and indoor environment performance of 4 demo buildings in 4 European countries and climates will be greatly improved due to holistic retrofit of the building envelope, the service systems, the integration of renewables and building management systems. The results and the accompanying research and dissemination efforts to support other actors dealing with building retrofits will lead to a multiplied impact on other schools and on the residential sector, since the pupils will act as communicators to their families. The user behaviour and the awareness of energy efficiency and indoor environment will be improved due to tailored training sessions. Zero emission buildings are a main goal in various country roadmaps for 2020. The demonstration buildings within the project may not completely reach this level as the aim of the call is cost efficiency and multiplication potential. The retrofit concepts will, however, result in buildings with far lower energy consumption than in regular retrofits with high indoor environment quality - thus leading the way towards zero emission. They can be considered as schools of the future. Results from national examples of zero emission schools will complete the information used for developing the deliverables such as guidelines, information tools, publications and a community at the EU BUILD UP portal. The project is based on close connection between demonstration, research and industry represented by the “design advice and evaluation group”. The proposal idea was introduced at the E2B association brokerage event with high interest which results in a consortium including well-known partners from the building industry.

Keywords: retrofit,school buildings,zero emission,indoor environment,user behaviour,leading example,school of the future,renewables,high performance buildings
Information and Communication Technologies for the Full Electric Vehicle (ICT4FEV)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Contribution of the ICT Theme to Public-Private Partnerships for R&D in the European Economic Recovery Plan
Action type: Coordination and support actions
Countries involved: Germany,Italy,Germany,Austria,Netherlands,France,Italy
Call:  (FP7-2010-ICT-GC, 2010)
Start date: 2010-05-01
End date: 2012-09-30
Duration (months): 29.0
Total project cost (EUR): 1286509.0
EU funding (EUR): 999474.0
Participants: 7
Project status: CLOSED

The proposed coordination action addresses enabling technologies of full electric vehicles (FEV). The focus of the initiative is set on ICT which open new technology paths towards energy efficiency, functionality and usability and are complementary to future advances in performance of battery cell technology. To fight climate change, cut emissions and secure energy supply, transport based on FEVs will soon be strongly demanded by public and private stakeholders worldwide. It can be foreseen that early technology leadership will be determinant for the global competitiveness of major European industries such as the automotive, energy and ICT sector. ICT4FEV is aiming at building a R&D community, creating a European roadmap and recommending standards, regulations, business cases and R&D priorities for the FEV. In its core consortium it will therefore bring together for the first time major industrial partners to start a dialogue on a common understanding about impact, R&D priorities, infrastructure needs and requirements. Opportunities of technology transfer, e.g. between electric road vehicles and aircrafts, shall be taken into account and foresighted recommendations shall be made. To broaden the view of its work, ICT4FEV will involve more than 15 key stakeholders representing both academia and the involved industry sectors from across Europe. Particularly involved will be vehicle manufacturers and suppliers, companies from the energy sector focussing on the vehicle-to-grid interface (V2G) and companies from the electronics and semiconductor sector dealing with components and systems. Furthermore, representatives of European and international public authorities shall take part in the dialogue. The outcome of ICT4FEV will serve as guideline for setting strategic priorities on a European level and by presenting the European FEV strategy at international events it will help to demonstrate the innovation strength of Europe in the field of FEV. At the same time, ICT4FEV shall serve as a platform for public information and network building in Europe.

Keywords: full electric vehicle,green cars,fev
Smart Energy Efficient Middleware for Public Spaces (SEEMPUBS)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Contribution of the ICT Theme to Public-Private Partnerships for R&D in the European Economic Recovery Plan
Action type: Collaborative project
Countries involved: Italy,Italy,Germany,Sweden,Belgium,France,France
Call:  (FP7-2010-NMP-ENV-ENERGY-ICT-EeB, 2010)
Start date: 2010-09-01
End date: 2013-08-31
Duration (months): 36.0
Total project cost (EUR): 4238591.0
EU funding (EUR): 2900000.0
Participants: 10
Project status: CLOSED

SEEMPubS specifically addresses reduction in energy usage and CO2 footprint in existing Public buildings and Spaces without significant construction works, by an intelligent ICT-based service monitoring and managing the energy consumption. Special attention will be paid to historical buildings to avoid damage by extensive retrofitting. SEEMPubS will provide control of appliances to effortlessly optimise energy efficiency usage without compromising comfort or convenience and offering decision makers strategies and tools needed to plan energy saving measures. SEEMPubS will make use of the service-oriented middleware for embedded systems being developed in the Hydra project and use its huge potential to create services and applications across heterogeneous devices to develop an energy-aware platform. The SEEMPubS platform will provide necessary functionality and tools to add energy efficiency features to monitor dynamic sensor data in real time, taking advantage of natural resources (like daylight and solar energy) and controlling the operation of both passive and active environmental systems to ensure the best possible comfort conditions with the most efficient use of energy. SEEMPubS will use its real-time energy-awareness services for all users of the Public Space and combine awareness services with a community portal. This will enable collective, community activity motivating positive competition in saving energy, complemented by courses on towards the education on energy efficiency and sustainability. The functionality of this system will be demonstrated on existing buildings at the Politecnico Campus like the Valentino Castle. The validation of the most significant SEEMPubS results will allow to elaborate an energy efficient model for existing buildings and public spaces with a significant economical impact all over Europe. In fact this model could also be applied on many different historical buildings (e.g.palaces, castles and museums) where old energy systems are already in place, avoinding in this way expensive construction works and possible damages.

Keywords: interoperability,energy conservation,intelligent system,real time adaptation,service-oriented-architecture,energy-awareness services,middleware,enduser involvement,long-term sustainability.
WaferLevelOptics - Specific Technological Developments to Create an Intelligent and Scalable Production Platform for Glass Optics Manufacturing (WAFERLEVELOPTICS)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: New production
Action type: Collaborative project
Countries involved: Germany,Finland,Switzerland,Luxembourg,Germany,Germany,Germany,Denmark,Sweden,Germany
Call:  (FP7-2010-NMP-ICT-FoF, 2010)
Start date: 2010-10-01
End date: 2013-09-30
Duration (months): 36.0
Total project cost (EUR): 3737159.4
EU funding (EUR): 2554564.0
Participants: 10
Project status: CLOSED

To meet the future market needs by innovative approaches using state of the art machining equipment the overall goal of the project WaferLevelOptics is the development of a new production platform for wafer scale moulded glass optics.

Keywords: micro optics,scalable platform,glass moulding,replication,integrative process chain