Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
From machines to smart systems: Cloud-based IoT for lift modernization and predictive maintenance (e-BlueBox)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-08-01
End date: 2018-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Used every day, the lifts provide an essential means of fast, safe and comfortable access to different floors in buildings. The installation of lifts in new or existing buildings has an increasingly important role to play in an ageing society and as a growing population is moving to cities. In the city of the future, the most important transportation system will not be cars, buses, subways, or even futuristic monorails, it will be the lift! Europe counts today more than 5.85 million lifts in service. Around 70% of them were installed before 1999 and they do not assure the highest safety levels currently expected, which means that fatal accidents still occur in the EU. Moreover, lifts are a major capital investment for building owners and managers. Current maintenance procedures are based on periodic inspections which, despite the number of visits, produce poor results in terms of performance (MTTR and MTBF) and uptime, implying high maintenance costs and low effectivity. The combination of old systems and poor maintenance models is holding back the EU lift market. The lack of data impedes the optimization of maintenance models. Leveraging digital technologies such as IoT (Internet of Things) to extract data out of connected lifts can solve this problem. Our company IOTTY is an Italian start-up fully aware of the importance of using the Internet of Things in the lift industry to anticipate equipment failures and respond more quickly to critical situations. Addressing the concern of lift manufacturers, maintenance companies, building owners and insurers, we present e-BlueBox, an innovative tool for lift modernization that leverages the IoT to reach higher standards of safety and implement predictive maintenance. With clear benefits (-25-30% accidents, -10-40% maintenance costs, equipment downtime reduced by 50%), e-BlueBox will allow IOTTY to grow sustainably, capturing €29.6 million revenues in its first 4 years of commercialization.

Keywords: cloud platform,sensor network,predictive maintenance,safety,lifts,elevators,internet of things
Innovative DEsign for Reliable PLANEt bearings (IDERPLANE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Italy,Italy,Italy,Italy,France
Call: Innovative design for reliable and low weight power gearbox planet bearings (H2020-CS2-CFP07-2017-02, 2017)
Start date: 2018-11-01
End date: 2023-11-30
Duration (months): 61.0
Total project cost (EUR): 813887.25
EU funding (EUR): 749968.75
Participants: 5
Project status: SIGNED

The high power transmissions that have to be designed for modern highly efficient turbofans need the extensive application of epicyclical gears with planet gear containing an integrated bearing. These components are subjected to severe rolling contact fatigue (RCF) conditions as many others (e.g. wheels/rails of high speed trains): propagation of micro-cracks starting from the bearing race surface and leading to spalling is a typical damage mode of these components. The main idea behind IDERPLANE is to analyze the problem not in terms of the usual stress-based design of gears, but rather on damage tolerance concepts. This kind of analysis is meant at understanding/measuring the risk of a catastrophic failure in the case of development of subsurface propagation of cracks driven by shear stresses. Incidentally, it has to be emphasized that spalls can lead to sub-surface cracks only once they have reached a critical size. If this could be seen an established route, unfortunately RCF is a grey area where there are no data available for such an analysis (that should be based on reliable crack growth curves), because it is very difficult to make cracks propagate under shear as it happens in RCF (and as it was shown in the known failures of planet gear containing an integrated bearing). This is the strength and unicity of the IDERPLANE consortium where the partners have special technology and abilities: to obtain crack growth curves under RCF conditions on specimens (PoliMI) ; to reproduce the subsurface crack propagation in bi-disks experiments (UniBS); to follow and track the development of cracks under complex load conditions (INSA).

Keywords: planet bearing,power transmission,defect tolerance,reliability
AUTOMATED THERMOGRAPHIC INSPECTION SYSTEM FOR THE INSPECTION OF AERONAUTIC WELDINGS (AUTHENTIC)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Austria,Germany,Spain,Sweden
Call: Automated thermography for inspection of welded safety critical engine components (H2020-CS2-CFP11-2020-01, 2020)
Start date: 2021-01-01
End date: 2022-12-31
Duration (months): 24.0
Total project cost (EUR): 759350.0
EU funding (EUR): 699387.5
Participants: 4
Project status: CLOSED

Thermography opens a new paradigm because shifts actual manual inspections like those of Fluorescent Penetrant Inspection (FPI) into automated inspection and detection to avoid human errors. AUTHENTIC addresses the development and adoption of automated inductive active thermography to improve the probability of detection (POD) of surface defects generated or appearing in welded safety-critical engine components both for in-process control and for final inspection and quality acceptance. The high sensitivity of the technology enables the detection of cracks down to 200 μm. An improvement higher than 50% is expected on the detectable critical defect size, on POD basis. Automation will be implemented during the inspection process through an adequate robotic system and also during the defect detection, characterization and localization, thanks to the developed algorithms. Furthermore, a second sensory will be added to the main system in order to tackle geometrically complex cases where thermography might fail or give a partial result due to accessibility issues. The system developed will provide (i) faster inspections on full-scale components, (ii) elimination of human subjectivity from inspections, and (iii) healthier and cleaner working environment for technicians. The easier, faster and more accurate maintenance inspections will lead to safer aircrafts and to the extension of their lifetime contributing to a globally more innovative, sustainable and competitive EU aircraft industry. AUTHENTIC will cover from the complete definition of the NDT system based on process and inspection requirements to its implementation and validation through the inspection of a real component provided by GKN (topic leader). The achievements of project objectives will be supported by the multidisciplinary consortium formed by experts in thermography (LORTEK, ULEOEBEN and EDEVIS), simulation (ULEOBEN), automated inspection (EDEVIS), sensorics (HV) and welding metallurgy (LORTEK, HV).

Keywords: inductive active thermography,ndt nondestructive testing,welding inspection,automation,defect detection algorithms
Understanding and manipulating the dysregulation of interneurons in schizophrenia (SchizoFree)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-05-01
End date: 2023-04-30
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

Schizophrenia is an incurable disease hallmarked by the presence of positive, negative and cognitive symptoms. Currently, antipsychotic drugs are used to treat some of the positive symptoms, including psychosis but fail to alleviate cognitive and negative symptoms. Psychosis is associated with striatal hyperdopaminergia, hypothesized to be due to abnormal activity of midbrain dopamine neurons. Dopamine levels are already elevated in patients with schizophrenia before the onset of psychosis, suggesting that increased dopamine levels might be secondary to other alterations occurring earlier in life. Additionally, functional alterations in the prefrontal cortex contribute to the disease, and interestingly abnormally increased activity in cortical excitatory neurons leads to striatal hyperdopaminergia in mice. However, the mechanisms and developmental trajectory underlying schizophrenia is still unclear, challenging the development of novel treatment strategies. Previous work from the Marin and Rico labs has shown that reducing excitatory synapses received by Parvalbumin (PV)-expressing interneurons through deletion of tyrosine kinase receptor ErbB4 from these neurons causes a schizophrenia-like phenotype and striatal hyperdopaminergia. The first aim of this fellowship is to use this mouse model and answer the question whether striatal hyperdopaminergia is caused by interneuron dysregulation in the cortex and/or striatum. The second aim is to identify the mechanisms causing the abnormal regulation of striatal dopamine neurons and to characterize a developmental trajectory of the disease. In the third aim, I attempt to normalize interneuron function to alleviate a wider spectrum of schizophrenia symptoms, including symptoms in the cognitive and negative domain. This is important because it would allow a better treatment outcome and the identification of biomarkers for earlier detection of patients at risk.

Keywords: interneurons,cortex,striatum,dopamine
LEMON Less Energy More OpportuNities (LEMON)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Market uptake of energy innovation
Action type: Coordination and support actions
Countries involved: Italy,Italy,Italy,Italy
Call: Project development assistance for innovative bankable and aggregated sustainable energy investment schemes and projects (H2020-EE-2015-4-PDA, 2015)
Start date: 2016-02-01
End date: 2020-01-31
Duration (months): 48.0
Total project cost (EUR): 628855.0
EU funding (EUR): 628855.0
Participants: 5
Project status: CLOSED

LEMON "Less Energy More OpportuNities" focusses on energy investments in the Social Housing sector and involves 2 Housing Company of Emilia Romagna Region ACER Reggio Emilia and ACER Parma, launching 15,29 M€ of energy investments in 622 private and public social housing dwellings. The project will develop innovative, bankable and aggregated sustainable energy investment scheme based on the following aspects: - LEMON will be a pilot project for the Emilia Romagna Region Social Housing Programme, creating a new financing model for energy retrofit interventions and developing a EPC model contracts that will mobilize 15,29 million Euros of investments in social housing buildings energy retrofitting, in order to reduce the buildings energy demand. LEMON will support the investments combining different financing instruments available at National and Regional level (ERDF funds, National financing, National incentive “Conto termico” and loans) and in particularly it will charge part of the investment on the rents according to the reduced energy costs for the tenants. - LEMON will develop the Energy Performance Tenancy Agreement (EPTA). The contract between the tenants and the ACERs will ensure that a portion of the investments covered by ACER Reggio Emilia and ACER Parma with a loan is charged on the rents for as long as the loan is repaid, leveraging on the savings produced by the retrofit interventions.. The replication of the project will be based on a wide dissemination and capacity building strategy among the social housing companies at regional and national level, and also among other sectors (City councils, Provinces, Regional, public authorities, Groups that represent e.g. Local Government Association, National public authorities, Organisations working in the field of energy efficiency, ESCos, Companies) . The project results will be disseminate across Europe towards the EU networks Climate-Kic and Housing Europe.

Keywords: social housing,innovative investment scheme,epc contract,epc capacity building,tenance engagement
Innovative Methodologies and technologies for reducing Aircraft noise Generation and Emission (IMAGE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Spain,Germany,Spain,Germany,Sweden,Belgium,Belgium,Sweden,France,Netherlands
Call: International cooperation in aeronautics with China (H2020-MG-2015_SingleStage-A, 2015)
Start date: 2016-04-01
End date: 2019-06-30
Duration (months): 39.0
Total project cost (EUR): 1799810.0
EU funding (EUR): 1799810.0
Participants: 12
Project status: CLOSED

The proposed project, IMAGE, is relevant to Topic MG-1.10-2015, aiming to enhance the EU-China collaborative effort focusing on “Innovative methods and numerical technologies for airframe and engine noise reduction”. The project consortium consists of 12 partners. The purpose of IMAGE is to investigate experimentally and numerically innovative airframe and engine noise-reduction technologies and, in a systematic conjunction, to develop robust methodologies of addressing these technologies. Airframe noise is addressed by tackling landing gears and high-lift devices, and engine noise through its fan component. Fundamental investigations of three key control strategies are carried out: plasma actuation, turbulence screens and innovative porous materials, on a platform of three configurations, relevant to airframe and aero-engine noise generation and control, including a wing mock-up, tandem cylinder and engine-fan duct. Beyond this, IMAGE explores further the installation effect of aeroacoustic engine-jet/wing interaction with a simplified configuration, as well as low-noise concepts and optimal noise-actuation methods by means of aeroacoustic optimization. The project will conclude a comprehensive understanding of the physical mechanisms concerning flow-induced airframe and engine-fan noise generation, propagation and control, and of further improvement of beam-forming technology and noise source identification in aero-acoustic experimental analysis. The experiment will generate well-documented database, supporting the development of numerical modelling and simulation methodologies for reliable validation and verification. To this end, with technical synthesis and industrial assessment, the noise control methods will be optimized and be facilitated towards potential industrial use, and the methodologies developed should form a robust part of advanced tools in industrial practice.

Keywords: airframe and engine noise,noise reduction,control,plasma actuation,turbulence screens,acoustic liners,experiment measurements,installation effect,aero acoustic optimization
Structure-function studies of the human FASTK family of mitochondrial proteins with putative novel RNA binding domains – the helical FAST motifs and the small RAP domain (FAST-RAP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Poland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-01
End date: 2017-09-30
Duration (months): 24.0
Total project cost (EUR): 134462.4
EU funding (EUR): 134462.4
Participants: 1
Project status: CLOSED

The purpose of this project is three-fold. The main aim is to elucidate the structure of two novel RNA binding folds: the helical FAST motifs and the small RAP domain that are predicted in the Fas-activated Serine/Threonine Kinase (FASTK) protein family. To this purpose, I will employ protein crystallography and small angle X-ray scattering to obtain models of FASTK proteins and their domains. The second objective is to understand the function of the FASTK family of mitochondrial RNA-binding proteins that were originally annotated as atypical kinases. The eponymous FASTK engages in processes similar to its interaction partner, the post-transcriptional regulator TIA-1, whereas some of the other five human paralogs are necessary for cellular respiration. I will use purified FASTK proteins to study their enzymatic activities and RNA-binding properties in vitro, which should clarify their functional classification as kinases or post-transcriptional regulators. Additionally, follow-up studies may include validation of the findings through informed mutagenesis, identification of RNA targets, protein partners, and selected phenotypes in RNA biology. The final goal of this project is to enable a young researcher to establish herself as an independent researcher, creating a group which will focus on mitochondrial RNA-binding proteins and employ X-ray crystallography as the main tool. Altogether, this interdisciplinary project will 1) Impact various fields of research, such as structural and RNA biology 2) Has the potential for applications in human health due to the connections of the FASTK family to mitochondrial and inflammatory diseases, 3) Significantly develop the career of a talented researcher and 4) Contribute to the academic and research excellence at the University of Warsaw by establishing a new research group, introducing structural biology expertise, and bringing together local and international collaborations.

Keywords: protein crystallography,rna binding domain,helical repeats,post transcriptional regulation,atypical kinase,mitochondrial disease
Multi-protein interaction kinetics by single molecule methods (PROSINT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-04-01
End date: 2021-09-30
Duration (months): 66.0
Total project cost (EUR): 1882500.0
EU funding (EUR): 1882500.0
Participants: 1
Project status: CLOSED

Objective of this proposal is to obtain a real time picture of how components of a multi-protein complex interact to perform complex regulated tasks, in particular to see how a protein system might be more than the sum of its components. In living organisms many proteins work in complexes to form multicomponent protein machines and to regulate cellular processes. The function of such multicomponent machines is usually addressed by dividing them into a collection of two state systems at equilibrium. Many molecular machines work in large complexes with multiple states out of equilibrium by utilizing the energy of ATP hydrolysis. In this proposal the real time kinetics of multi-protein interactions in and out of equilibrium will be investigated using single molecule methods. The succession of association and dissociation steps as well as large conformational changes within the proteins will be monitored simultaneously with multicolour single molecule FRET in real time. In order to observe at the same time the folding state of proteins, a combination of optical tweezers and single molecule FRET will be developed. Finally, a combination of microfluidics for fast mixing and single pair FRET will be developed to investigate interactions of low affinity. A large part of the experiments will focus on the example of the heat shock protein Hsp90 system, which consists of co-chaperones, clients and nucleotides. Altogether, these interdisciplinary experiments will yield unprecedented information on multi-component interactions in equilibrium and out of equilibrium on timescales from sub milliseconds to hours. I am confident that these studies will have an impact on the understanding of the Hsp90 machinery as well as general principles of multi-component protein systems, which is the basis for understanding cellular processes.

Keywords: single molecule,fret,protein kinetics,hsp90,physics of biological systems
Sources of rationality: arousal and the use of rational and heuristic decision strategies (SOURCES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-08-15
End date: 2020-08-14
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

Research in psychology and neuroscience has provided a rich amount of data on the ways in which humans make decisions. Behavioral studies show that for various kinds of problems, people often use simple decision heuristics in order to overcome limitations in time, knowledge and cognitive abilities. Neurophysiological studies show that the use of decision strategies is associated with activation of various brain structures, including novel parts of the cortex and old, subcortical structures. Research by the author of this proposal suggests that the neural systems governing arousal may shape predecisional information processing and decision strategy use. Advanced studies by the supervisor of this project show in detail how arousal systems impact cognitive functions, with a special focus on attention. The knowledge of the dynamics of attention can be applied to advance our understanding of decision-making and the use of rational and heuristic strategies. The general aim of this project is to explore the neural underpinnings of decision-making. Specifically, this project aims to advance a theoretical model of the impact of arousal on decision strategy use, and to test this model in experiments with the use of various neuroscience methods: fMRI, EEG and eye-tracking. The applicant will receive intensive training focused on acquiring advanced skills of fMRI, EEG and eye-tracking data acquisition and analysis. The training will take place at the Leiden Institute for Brain and Cognition, which hosts several groups that work on topics of close relevance for the current proposal. In turn, the applicant will contribute knowledge of value-based decision making, including the knowledge of computational models of decision-making, the impact of stress on cognition and the role of hormones in decision making. This will allow for a mutual exchange of skills and ideas between the host and the applicant, which should result in novel insights into the mechanisms of decision making.

Keywords: decision making,bounded rationality,decision strategy use,heuristics,cognitive limitations,emotions,arousal,noradrenalin,locus coeruleus,cognitive models of choice