Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
An unprecedented water-recycling system for washing, rinsing and drying of thermal insulated containers within the Food Industry (Optainer)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Belgium
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The cleaning thermic insulated containers used for safe and efficient transportation of temperature-controlled goods is a crucial step in food operations. It requires a high degree of cleanliness and drying efficiency to ensure the hygienic conditions for safe product transportation. Nowadays, several methods have been proposed to clean insulated containers but considered technically limited. They can only wash efficiently outside and not inside of the box which compromises the hygienic conditions. And, when they do, the drying step is often neglected leaving biological hazard into the containers. Moreover, they are time consuming, expensive (requires person to operate) and face an important issue of excess water usage (over 46L per container). The sanitizing process also currently requires hot water (65°C) to remove bacteria which further increases cost and energy use. Driven by the increasing concern of supermarket retailers, LVP Engineering & Constructions has designed and developed Optainer: An automatic water-recycling Wash&Dry station for insulated containers sanitation. Our innovative recycling system will reduce over 97% of water consumption. It will increase productivity by 60% disposing of 40 containers per hours vs 20 with standard solutions and reduce energy consumption with no need of heating water for sanitation. It will fully answer supermarket retailers’ specification for a more efficient, economic, easily to operate, safer and water efficient solution to insulated container sanitation. Since 2005, our company has been developing standard automatic washing installation for insulated containers with an important German retailer throughout the EU. Well aware of the need, our Optainer project has the potential to extend our customer portfolio and, thus, increase our revenue. We expect from Optainer commercialisation an accumulated turnover of €30 million with €10.2 million accumulated profit (ROI of 3.2) and foresee to create 21 new jobs by 2026.

Keywords: thermal insulated containers,transportation,temperature controlled goods,hygiene,washing,rinsing,drying
Computer Aided Multispectral Ulstrasound Diagnostic Device (UltraEASY)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Germany
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-1-2015, 2015)
Start date: 2015-07-01
End date: 2015-10-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Every 40 seconds, someone in Europe suffers from a stroke killing 1,000 Europeans daily. The resulting economic damage is immense. In the 2006 wake-up-study funded by the EU the economic damage in Europe amounts to 36 billion EUR per year. The objective of this project is the clinical validation of SoNovum AG’s UltraEASY™ II Brain Vitals Monitoring System and the underlying CAMUD technology for diagnosing and monitoring neuropathologies in acute events and at-risk patient groups. CAMUD stands for “Computer Aided Multispectral Ultrasound Diagnostics” and is a novel diagnostic method based on molecular acoustics. It measures the feedback of ultrasound waves on multiple frequencies, which is interpretable for the first time thanks to modern computer technology. The technology enables, among other things, a fast, very precise and non-invasive diagnosis of the brain tissue in the beginning of the therapeutic time frame as well as further, continuous monitoring. Therewith physicians will be able to diagnose acute events more quickly and preventatively at-risk patient groups, even before harmful incidents occur. Initial target market groups for UltraEASY II include the stroke units in clinics as well as family and specialist's practices in Europe with regard to global markets as well. Because of high mobility, flexibility and the small acquisition costs, it is well suited as basic equipment for practices as well as, in its mobile version, for helicopters, rescue vehicles and ambulances of clinics and emergency organizations. The objectives of this Feasibility Study are the examination of the market acceptance towards UltraEASY II, addressing clinics and physicians as well as involving patients, patient organizations and health insurance carriers, in order to conduct the risk evaluation for the final realization of the CAMUD technology in the MedTech sector and conclude the development of final innovation strategies for Phase 2.

Keywords: multispectral,ultrasound,stroke,neuropathologies,brain,monitoring
The first holistic mobile game for evaluating and supporting the development of social and emotional skills and competences in childhood (SEL 360 Gomins)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-07-01
End date: 2016-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

SEL 360 Gomins® aims at setting a new standard for tracking and supporting children to develop social and emotional skills and competences while early detecting any social-emotional difficulties and behaviour disorders. In order to optimize acceptance and success rates, SEL 360 Gomins® is based on the objective and accurate measurement of physiological, psychological and behavioural parameters through neurophysiological sensors, voice and video analysis while the child is playing our fun games through mobile devices. The technology behind this gaming child-centred solution makes it possible to gather and analyse relevant parameters and information anytime and anywhere. The system has demonstrated to be applicable for diagnosis, monitoring and training of emotional skills and social behaviour in childhood –fostering development and self-regulation- and brings as clinical outcome normalized social behaviour and improved schools performance. SEL 360 Gomins®’s unique design and technology allows us to achieve two clinical objectives: 1. To identify at early stage, by objectively and accurately quantifying in real time, deviations and deficits in social behaviour competences and emotional skills 2. To deliver personalized reports, enabling optimal training by parents, teachers and schools at home and schools under remote medical support and tracking. A feasibility study (Phase 1) will be conducted to confirm the viability for commercializing SEL 360 Gomins® at global level and then proceed with the validation of its performance and efficacy in clinical trials (Phase-2). Together, this will pave the way for a successful commercial launch on 2019 to deliver the first scientific-based game for supporting million of children to enhance their social behaviour and emotional skills. Thanks to this project, Álava Reyes will become a European point of reference of innovation in the field of psychology, generating 14.511.955 € cumulative revenues by 2023.

Keywords: social skills,training,mobile game,children,learning
Whole-brain dynamics underlying self-generated behaviour (Spontaneous ZeBrain)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: France
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-05-01
End date: 2023-10-31
Duration (months): 78.0
Total project cost (EUR): 1997360.0
EU funding (EUR): 1997360.0
Participants: 2
Project status: SIGNED

The first behavioural theories conceived the organism as primarily driven by external sensory stimuli. However, the energy associated with momentary demands of the environment represent ~1% of the brain's total energy budget, implying that the intrinsic activity represents a major aspect of the brain's function. Indeed, more recent theories such as cognitivism and embodiment describe the organisms as capable of generating complex behaviours emerging from the brain's intrinsic dynamics. Past and current studies that investigated the neuronal basis self-generated behaviours mainly focus on the readiness potential (RP) signal, a build-up ramping activity in the premotor cortex, occurring ~ 2 sec before the movement's onset. However, the neuronal mechanisms underlying the generation of self-generated behaviours (how RPs are generated), the involvement of other regions, and how the brain codes the impending movements (activity predictive of the onset and type of movement), still remain poorly understood. The combination of light-sheet microscopy, optogenetics, and the zebrafish larva model enables monitoring whole-brain dynamics in an intact behaving vertebrate. Moreover, the diverse yet limited and well described repertoire of motor behaviours will enable to perform experiments in more natural unconstrained conditions, in comparison to previous studies, which were structured in trials and limited to one or two behavioural choices. These advantages will allow us to go beyond the current state-of-the-art in the field. More specifically, we propose to investigate the following specific aims: 1) Whole-brain dynamics basis and mechanisms underlying self-generated behaviours. 2) A comparison between the neuronal pathways underlying the initiation of self-generated and sensory induced behaviours. 3) The internal and external modulation of self-generated behaviours.

Keywords: neuronal circuit dynamics,spim,zebrafish,optogenetics,behaviour,internal decisions,computational neuroscience,calcium imaging
Forecasting with large datasets: A time varying covariance matrix (FORECASTING)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Cyprus
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-06
End date: 2018-09-05
Duration (months): 24.0
Total project cost (EUR): 151648.8
EU funding (EUR): 151648.8
Participants: 1
Project status: CLOSED

Recently there has been considerable focus on methods that enable time varying estimation of parameters in econometric models in the presence of, possibly stochastic, structural change. An interesting strand of this literature dispenses with the, computationally expensive and theoretically unclear, standard Bayesian estimation methods in favour of kernel estimation. In this project we intend to extend that strand of the literature to the case of large dimensional datasets and perhaps the most commonly explored problem of covariance estimation. Our primary focus will be to combine kernel estimation with fixed coefficient estimation methods for large dimensional covariance matrices. We will then try to provide theoretical results that allow for time variation in the large data generating process. This is a novel extension in the literature. To strengthen our theoretical results, we aim to provide an extensive Monte Carlo analysis and illustrate the utility of our methods in terms of out of sample forecasting. The proposed estimators have many interesting empirical applications. On top of the theoretical paper, our aim is to provide, two empirical papers, in the area of Macroeconomic Forecasting and Optimal portfolio allocation. To this end, we will use the proposed estimators, to forecast key macro variables with large dimensional linear regression, and compare with similar, data rich methods, that are currently used in the literature. Finally we will combine our methodological advancements with optimal portfolio allocation theories. Our preliminary empirical results show that the benefits from the proposed estimators are expected to be high and significant.

Keywords: structural breaks,forecasting,covariance matrix,portfolio allocation,large datasets
Binary massive black hole astrophysics (B Massive)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Universe sciences
Panel description: Astro-physics/-chemistry/-biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Italy
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-09-01
End date: 2024-08-31
Duration (months): 60.0
Total project cost (EUR): 1532750.0
EU funding (EUR): 1532750.0
Participants: 1
Project status: SIGNED

Massive black hole binaries (MBHBs) are the most extreme, fascinating yet elusive astrophysical objects in the Universe. Establishing observationally their existence will be a milestone for contemporary astronomy, providing a fundamental missing piece in the puzzle of galaxy formation, piercing through the (hydro)dynamical physical processes shaping dense galactic nuclei from parsec scales down to the event horizon, and probing gravity in extreme conditions. We can both see and listen to MBHBs. Remarkably, besides arguably being among the brightest variable objects shining in the Cosmos, MBHBs are also the loudest gravitational wave (GW) sources in the Universe. As such, we shall take advantage of both the type of messengers – photons and gravitons – they are sending to us, which can now be probed by all-sky time-domain surveys and radio pulsar timing arrays (PTAs) respectively. B MASSIVE leverages on a unique comprehensive approach combining theoretical astrophysics, radio and gravitational-wave astronomy and time-domain surveys, with state of the art data analysis techniques to: i) observationally prove the existence of MBHBs, ii) understand and constrain their astrophysics and dynamics, iii) enable and bring closer in time the direct detection of GWs with PTA. As European PTA (EPTA) executive committee member and former I International PTA (IPTA) chair, I am a driving force in the development of pulsar timing science world-wide, and the project will build on the profound knowledge, broad vision and wide collaboration network that established me as a world leader in the field of MBHB and GW astrophysics. B MASSIVE is extremely timely; a pulsar timing data set of unprecedented quality is being assembled by EPTA/IPTA, and Time-Domain astronomy surveys are at their dawn. In the long term, B MASSIVE will be a fundamental milestone establishing European leadership in the cutting-edge field of MBHB astrophysics in the era of LSST, SKA and LISA.

Keywords: multimessenger astronomy,pulsar timing arrays,time domain astronomy,supermassive black holes
From chromatin fibers to lamina-associated domains: what are the recognition determinants? (I.am.a.LAD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-12-01
End date: 2023-11-30
Duration (months): 24.0
Total project cost (EUR): 175572.48
EU funding (EUR): 175572.48
Participants: 1
Project status: SIGNED

Lamina-associated domains (LADs) are large chromatin domains anchored to a protein meshwork coating the inner nuclear envelope, the nuclear lamina (NL). They cover 40% of the human genome and hold thousands of transcriptionally repressed genes. While some LADs can be locally detached from the NL upon gene activation, others are constitutively at the NL. This implies that LAD recognition and anchoring to the NL has to be tightly regulated to ensure acute gene expression. However, little is known about mechanisms governing LAD recognition and targeting to the NL. LADs are known to be A and T nucleotide-rich, but other sequence determinants have remained poorly characterized so far. In this project I will (1) investigate whether LAD recognition is directly linked to their high A/T content and (2) develop a novel tool to search for additional sequence determinants. First, I will insert in the mouse genome long DNA stretches of varying A/T percentages and determine whether A/T-rich sequences preferentially associate with the NL. Second, I will develop an approach to randomly scramble a LAD sequence organization. This method relies on the recombination between LoxP sites randomly inserted by local "hopping" of a transposable element. After determining the effects of the resulting rearrangements on NL association and expression of the surrounding genes, I will identify sequences that drive LAD formation. Besides, the cohesin complex partitions the genome into topologically associated domains and hence has a major impact in genome 3D folding. At last, I will investigate cohesin’s role in LAD formation and remodeling after recombination. Altogether, this project will result in an unprecedented characterization of LAD biology, a deeper understanding of cohesin’s role in genome folding and set up a novel genome-scrambling technique with large applications in genome biology.

Keywords: genome organization,lamina associated domains,nuclear lamina,genome scrambling,chromatin,transcription
Geological constraints on the crustal structure at InSight landing site, Elysium Planitia, Mars (GeoInSight)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-07-10
End date: 2019-07-09
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

The internal structure of Mars provides valuable insights into the differentiation and thermal evolution history of the planet. InSight (Interior Exploration using Seismic Investigations, Geodesy and Heat Transport) robotic lander, planned to launch for Mars in May 2018, will be the first lander using a seismometer to investigate the interior structure of Mars. However, the geologic context and subsurface structure of the landing site, which is crucial for understanding the geophysical data to be acquired by the mission, has not been well-established. Here I propose to organise a comprehensive study to constrain the subsurface geology using a suite of datasets acquired by previous orbital missions. I will work with Prof Cathy Quantin-Nataf at University of Lyon, taking advantage of the Mars dataset system (MarsSI) developed in the host lab. Through completion of a combined, thorough analysis of the morphology and thermophysical properties of the surface units, I will establish the boundary and time relationships of surface geological units. I can also characterize chemical and structural discontinuities in the crust, from investigation of impact craters that expose the mineralogy of the subsurface. The synthesis of these results will allow for reconstruction of the subsurface stratigraphic model for the interpretation of seismic data. This proposal demonstrates the transfer of knowledge to the host institution Claude Bernard University of Lyon 1; the training of the candidate in Mars geology research as well as project management; specific plans for dissemination and communication of the action results and the timeline and quality of implementation. The project puts the candidate and host organisation in good positions to participate in future Mars missions and reinforces the role of EU in Mars explorations. The science results of the proposed action will have great significance in understanding both the internal structure and fundamental geologic processes on Mars.

Keywords: mars,remote sensing,spectroscopy
OPEN INNOVATION TEST BED FOR ELECTROCHEMICAL ENERGY STORAGE MATERIALS (TEESMAT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Innovation actions
Countries involved: Spain,Italy,Germany,Spain,Italy,Ukraine,Spain,Belgium,Greece,Sweden,Belgium,Greece,Hungary,France,France,France,France,France,France,Netherlands,Luxembourg,United Kingdom
Call: Open Innovation Test Beds for Characterisation (IA) (H2020-NMBP-TO-IND-2018, 2018)
Start date: 2019-01-01
End date: 2022-08-31
Duration (months): 44.0
Total project cost (EUR): 10208602.76
EU funding (EUR): 8900252.16
Participants: 27
Project status: CLOSED

Despite more than 200 years of development of batteries, the physical limits of battery performance are far from being reached. The complexity of physio-chemical processes inside batteries render any development strongly dependent on a proper description and monitoring of the inherent evolution and interaction of all materials involved in the functioning of an electrochemical cell. It can be said that rarely any progress in a technology where all basic processes are understood did depend so much on characterization than electrochemical energy storage systems. The mean figures of merit (specific energy per mass, volume or cost unit, cyclability) can all theoretically be substantially improved, under the condition of a proper understanding of where and how their limits are reached in today’s industrialized systems. This underlines how much this important branch of our technological future depends on novel and accessible characterization techniques. Given this grand challenge, access to advanced characterisation solutions for the EU industry will be key to accelerate innovation and reduce the large cost share of materials. However, several bottlenecks are preventing access by companies to novel techniques, to which TEESMAT brings a comprehensive response by leveraging European strengths from 11 Countries and facilitating access to physical facilities, capabilities and services implementing novel characterisation solutions with unprecendenteed capability & performance. Instrumental to this is the launch of a sustainable Open Innovation Test Bed in which qualified public/private partners will demonstrate high-value services for materials advanced characterisation on industrial cases in the value chain of electrochemical energy storage systems. A strong EU community will be built up to propel the continuity of the initiative beyond TEESMAT with a viable, business driven and lean model of operation to create a market for advanced characterisation services, ultimately.

Keywords: material characterization,real time characterization,in line characterization,non destructive characterization,material modelling,electrochemical storage,battery safety,regulation for materials