Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
New generation of ion sources: from deep space missions to upstream nano-technologies (NEPTUNE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships (Return Phase)
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ukraine
Call:  (FP7-PEOPLE-2012-IIF, 2012)
Duration (months): 12.0
Total project cost (EUR): 15000.0
EU funding (EUR): 15000.0
Participants: 1
Project status: CLOSED

The main goal of the proposed NEPTUNE project (“New generation of ion sources: from deep space missions to upstream nano-technologies”) is to enhance the understanding of the physics and exploit the benefits of bipolar charged particle extraction from low temperature plasma. The first NEPTUNE prototype will be built and tested during the project implementation. In the NEPTUNE prototype the generated particle beam will be quasi-neutral, composed by ions and electrons or oppositely charged ions, without the need for an additional neutralization system. The NEPTUNE project brings together scientists who are experts in the area of formation of flows of oppositely charged particles, in order to address key fundamental issues at the leading edge of the subject: simultaneous bipolar particles extraction, space charge neutralization in complex systems and plasma - bipolar beam interactions.
Development of novel analytical and experimental approaches for an in-depth characterization and optimization of Silicon Photomultipliers (SIPM IN-DEPTH)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships (Return Phase)
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Russian Federation
Call:  (FP7-PEOPLE-2012-IIF, 2012)
Start date: 2015-11-02
End date: 2016-11-01
Duration (months): 12.0
Total project cost (EUR): 15000.0
EU funding (EUR): 15000.0
Participants: 1
Project status: CLOSED

Sensors capable of detecting single photons are of critical importance for a very wide range of scientific and technical applications in such areas as medical imaging, biotechnology, high energy physics, scientific instrumentation, communication, and homeland security, including, in particular, positron emission tomography, flow cytometry, Cherenkov cosmic ray telescopy, laser ranging, optical time domain reflectometry or beam loss monitoring in particle accelerators and light sources. Silicon Photomultipliers (SiPMs), in particular, are an emerging and very promising technology due to their photon number resolution at room temperature, insensitivity to magnetic fields, compactness and relatively low operating voltages. Furthermore, they are cheap to mass-produce, especially in comparison to conventional photomultiplier tubes. In order to evaluate their potential for a specific application, it is necessary to quantify their fundamental parameters as a particle detector, as well as in combination with scintillators or optical fibers used for signal generation and transport, in detail. In the frame of this Marie Curie IIF project, a comprehensive analytical probabilistic model of the SiPM response shall be developed that will take the specific excess noises of crosstalk and afterpulsing, nonlinearities and saturation effects into account. Based on this model, a full set of analysis, measurement and characterization methods will then be built up. This will allow for selecting an optimum SiPM design and model for a specific application as accelerator, nuclear or medical physics instrumentation and thus contribute to an overall improvement of the respective application. Finally, reliability and mass testing approaches and techniques, applicable for large-scale projects and focused on the balance between accuracy, simplicity and cost efficiency, shall be developed.
Optimizing Selectivity in C-H Functionalization Through Computational Design (CHOPTOCOMP)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships (Return Phase)
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: China
Call:  (FP7-PEOPLE-2012-IIF, 2012)
Start date: 2017-06-12
End date: 2018-06-11
Duration (months): 12.0
Total project cost (EUR): 15000.0
EU funding (EUR): 15000.0
Participants: 2
Project status: CLOSED

The activation of inert C-H bonds lies at the heart of organic chemistry. In particular C-H activation using transition metal catalysis has made a profound impact on complex molecule synthesis, but the area remains important for future discovery. At present the utility of synthetic methods based on C-H activation is hampered by the inherent difficulty of being able to selectively functionalize a single C-H bond in the presence of many others. Thus the ability to perform predictably site-selective C-H functionalizations on a given C-H bond in a complex substrate would be transformative for chemical synthesis. In this proposal we propose to perform computational studies on Pd-catalyzed C-H functionalization reactions, to uncover the inherent electronic bias of substrate structures on the site-selectivity. Calculations will be performed using density functional theory to characterize the mechanisms and catalytic cycle for Pd-catalyzed arylation of aromatic and heteroaromatic substrates. We will also develop quantitative models of reactivity and selectivity to deliver a greater understanding of the process, which will be used to generate predictions. The result will be a reliable predictive method with which to rationally design substrates and catalysts to deliver improved selectivities in C-H functionalizations.
EXPLORING (EMERGING) MYCOTOXINS RISK IN BEANS: A GLOBAL ALLIANCE FOR CLIMATE CHANGE RESILIENCE – MYCOBEANS (MYCOBEANS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Italy,Thailand,United Kingdom,Austria,Netherlands
Call: MSCA Staff Exchanges 2022 (HORIZON-MSCA-2022-SE-01, 2022)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 758342.86
EU funding (EUR): 726800.0
Participants: 11
Project status: SIGNED

The overall aim of the MYCOBEANS project is to strengthen the collaboration and promote the excellence of the academic and non-academic institutions involved with the common goal of exploring the emerging risk due to the occurrence of mycotoxins in legumes intended as alternative plant proteins, and therefore increase the resilience of the beans and legumes sector. Thanks to its top-class partnership, MYCOBEANS will bring innovation in mycotoxins diagnostics, toxicological evaluation, and biotechnological mitigation along the entire plant protein supply chain. The consortium, led by the University of Parma, Italy, involves internationally-leading academic and non-academic partners from the EU, UK and ASEAN countries, and has been designed around the already existing network of the International Joint Research Center on Food Security, Thailand. The strong connectivity already in place among partners will ensure the knowledge and expertise transfer, help build new research alliances, and enrich staff and young researchers' capacities from all members of the consortium. Young researchers will be exposed to a very diverse and multidisciplinary environment, thus ensuring a quick professional growth. The specific objectives will be achieved through an extensive program of interdisciplinary and intersectoral short- and medium-term staff exchanges and expert visits, involving doctoral and postdoctoral researchers as well as senior staff, aimed at cross-pollination among scientific disciplines, from chemistry to toxicology, biotechnology, industrial processing as well as regulatory science. As a complement, a rich program of training workshops, seminars, summer schools and dissemination and outreach activities will ensure a significant impact both at a professional career level as well as for industry and society.

Keywords: mycotoxins food safety alternative proteins climate change sustainability
Developing an integrative framework of goal flexibility, depression, and anxiety symptomatology (GoalFlex)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark,Australia,United States
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-02-01
End date: 2028-01-31
Duration (months): 24.0
Total project cost (EUR): 247553.28
EU funding (EUR): 247553.28
Participants: 3
Project status: SIGNED

Mental health is a global priority, with disorders such as depression and anxiety projected to become leading causes of disease worldwide by 2030. This underscores the urgent need for innovative research to understand protective factors and inform preventive measures. My fellowship aims to explore the potential protective effects of goal flexibility—the ability to adjust one’s goals and strategies in goal pursuit—against the development of depression and anxiety symptoms in emerging adults. Currently, we have limited understanding of how goal flexibility and mental health dynamics unfold over time or how and when to promote goal flexibility. By developing an integrative conceptual framework and adopting contemporary dynamic approaches such as ecological momentary assessment and computational modelling, I will demonstrate how these processes unfold over time. In this fellowship, I will pursue three research objectives: firstly, I will conduct a systematic review to develop a new conceptual framework linking goal flexibility and mental health processes; second, I will perform an empirical study using ecological momentary assessment to preliminarily evaluate the framework; and third, I will utilize computational modelling to simulate the proposed model, and to refine the conceptual framework. By achieving these objectives, this fellowship will guide future practices in developing personalized interventions for depression and anxiety. It will identify modifiable factors at critical time points, enabling the prevention or reversal of mental health symptoms.

Keywords: goal pursuit depression anxiety goal theory motivation personality mental health psychological framework development goal persistence goal disengagement well being goal adjustment
Sponge diseases under climate change: a multi-omics approach to the holobiont’s molecular functions (HOLOSPONGIA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

The Mediterranean Sea is a climate-change hotspot, which is often considered a miniature model of the world ocean. Therefore, it may allow foreseeing some of the expected global effects of climate change. Sponges hold numerous key roles in benthic ecosystems functioning. In the Mediterranean Sea, they create complex habitats serving as spawning and nursery grounds for fish and invertebrates, and their filter-feeding activity affects entire food webs and bentho-pelagic couplings. These keystone organisms are frequently suffering disease outbreaks and mass mortalities that are mostly triggered by marine heatwaves. Sponges are well-known holobionts that host complex symbiotic microbial communities. While some members of these communities offer adaptive advantages, others may contribute to disease outbreaks when environmental conditions change. This interdisciplinary research aims to discover the complex mechanism of thermal-stress-related necrosis and mortality of the sponge holobiont by studying the effect of heatwaves on the Mediterranean bath sponge Spongia officinalis through a holistic approach that includes morphological, transcriptomic, metagenomic, and metabolomic responses of the holobiont. To study causative as well as correlative disease events, the experimental setting of this project will combine in situ sampling of healthy and diseased individuals, as well as exposure of individuals kept in aquaria to simulated marine heatwaves. These will provide the first insight, not only to the change in the microbial community composition but also to the functionality of its members during thermal stress. It is imperative to understand the mechanism of disease prevalence and mortality and to likely suggest ways to mitigate this phenomenon. The expected increasing frequency of marine heatwaves can cause irreversible damage to entire ecosystems that rely on sessile invertebrates such as sponges and thus to numerous ecosystem services provided to human societies.

Keywords: sponge,metagenome,spatial transcriptomics,transcriptome,heat waves,climate change,metabolome,gene expression,microbiome,microbial community,holobiont
Understanding the multiple, meaningful, and overlapping elements of the social identity of children who are in foster care. How can foster care systems and foster carers provide quality care? (IDChild)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands,Belgium,Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-07-01
End date: 2028-12-31
Duration (months): 30.0
Total project cost (EUR): 271345.2
EU funding (EUR): 271345.2
Participants: 3
Project status: SIGNED

Children with diverse backgrounds (e.g., ethnic, sexual orientation and gender identity) and characteristics (e.g., abilities) are overrepresented in foster care, and evidence shows that these groups of children tend to face additional challenges, such as being misunderstood by professionals and foster carers and experiencing more placement breakdowns. Foster care systems can be disconnected from children’s needs and realities, thus reasserting normative standards and perpetuating inequalities. Additionally, there is reduced evidence on the specific needs of diverse groups of children who are in foster care, more specifically regarding their social identity and how the different elements of social identity intersect (race, ethnicity, gender identity, sex assigned at birth, sexual orientation, ability, religion, socioeconomic status, and other social categories). Young people who are in foster care, social workers, and foster carers across four foster care systems, England, Portugal, Spain, and The Netherlands, will share their perspectives, contributing to a deeper understanding of the three objectives of the project: i) to analyse the social identity development of children who are in foster care in four countries through the lens of intersectionality ii) to explore and compare the foster care systems (legislation, policy, practice, and research) and the support provided to children’s social identity development in four countries and, iii) to identify quality indicators of foster carers to support children’s social identity development, in four countries. The project will contribute unique and novel insights into children's social identity development, which can advance research, enhance practice processes of quality care, inform policy, and ultimately improve children's developmental outcomes.

Keywords: foster care,child protection system,role of foster carers,children s identity development,children in alternative care
Environmental Exposure Assessment Research Infrastructure Preparatory Phase Project (EIRENE PPP)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Coordination and support actions
Countries involved: Czechia,Austria,Belgium,Finland,France,Norway,Slovakia,Slovenia,Spain,Sweden,United States,Germany,United Kingdom,Greece,Iceland,Italy,Netherlands
Call: Preparatory phase of new ESFRI research infrastructure projects (HORIZON-INFRA-2021-DEV-02, 2021)
Start date: 2022-10-01
End date: 2025-09-30
Duration (months): 36.0
Total project cost (EUR): 2883570.0
EU funding (EUR): 2883570.0
Participants: 20
Project status: SIGNED

EIRENE RI (Research Infrastructure for EnvIRonmental Exposure assessmeNt in Europe) project prioritised in the 2021 Update of the ESFRI Roadmap fills the gap in the European infrastructural landscape and pioneers the first EU infrastructure on human exposome (environmental determinants of health). EIRENE PPP aims to prepare the implementation of EIRENE RI as a consolidated European research infrastructure enabling the development of advanced technologies and complementary services on the characterization of complex environmental exposures and their impact on the European population. This will promote European excellence in Environmental & Health research by providing European researchers with transnational and/or virtual access to harmonised capacities, unique services, and comprehensive data addressing the current and future needs of public authorities.

Keywords: research infrastructure,data infrastructure,esfri,exposome,environment and health,environmental exposure,risk assessment,emerging chemicals,users access,services to users,eosc,fair data
The Collective Bystander (COLLECTIVEBYSTANDER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 1999181.25
EU funding (EUR): 1999181.0
Participants: 1
Project status: SIGNED

The public myth about passive bystanders originated 50 years ago with the case of Kitty Genovese, a young woman raped and murdered in New York. Reporters claimed 38 people witnessed the crime but did nothing to help her. Although the police case file later showed that some bystanders in fact had tried to help, the incident inspired decades of experimental studies trying to explain why bystanders in the presence of others remain inactive toward persons in need of help. While this ‘bystander effect’ is among the most replicated findings in the social sciences, recent video observations of real-life violent emergencies show that bystanders in groups are far from passive. This Collective Bystander program aims to explain why and how bystanders take action to help in public emergencies. Utilizing state-of-the-art video analysis, the largest dataset of CCTV footage ever assembled (4,000 clips of emergencies in Cape Town and Amsterdam), and virtual reality experiments, it will advance an explanatory model that identifies the causal mechanisms that drive helping—a model generalizable beyond experimental settings and violent emergencies. It breaks new scientific ground by: (1) offering a theory that can explain why bystanders take collective action in real-life emergencies, instead of assuming that helping is an individual decision and responsibility; (2) studying how helping happens, rather than focusing on the lack of helping or merely establishing whether bystanders help or not; (3) providing insight into how the type of emergency influences helping behavior; (4) elucidating the interactional mechanisms that prompt helping, moving beyond merely examining variables that correlate with helping; (5) integrating the real-life validity of video observation with the causality-testing capacity of virtual reality experimentation. In sum, the program will set a new research agenda that shifts the focus from individual inaction to collective action in explaining bystander helping.

Keywords: helping,groups,emergencies,conflicts,aggression,violence,peacekeeping,third parties,guardianship
Solving the 'time puzzle' of epigenetic effects on child mental health (TEMPO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-06-01
End date: 2027-05-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

TEMPO aims to solve the newly discovered epigenetic 'time puzzle' of child mental health. Recently it has been observed that common mental health problems in children (e.g. hyperactivity, poor impulse-control) are associated with epigenetic patterns at birth - a mechanism that regulates gene activity in response to genetic and environmental influences. Curiously, however, this association is lost when measuring the same epigenetic patterns later in development. This discovery is highly unexpected and potentially ground-breaking: the existence of timing effects could lead to new insights into the origins of mental health and open much-needed opportunities for early risk detection. Yet, what factors drive epigenetic timing effects, how they manifest and why they occur is currently a puzzle. To solve it, TEMPO will combine innovative, multidisciplinary approaches and the generation of exceptional new data in a unique set of longitudinal European cohorts to address the what, where and why of epigenetic timing effects. Three work packages will be implemented to: (i) Systematically characterize unknown properties of epigenetic timing effects, including their genomic scale, specificity to mental health and persistence into adulthood, using advanced quantitative methods; (ii) Locate epigenetic timing effects with greater precision, by establishing whether effects are driven by epigenetic patterns in specific tissues and cell-types that are found at birth but not later in life; and (iii) Explain timing effects, by disentangling the genetic and environmental origins of epigenetic timing effects on mental health, drawing on the power of genetically sensitive, quasi-experimental designs. As well as leading a breakthrough in this emerging field and addressing a major knowledge gap at the intersection of biological and psychological sciences, TEMPO has the potential to set in motion a paradigm shift in the way that we conceptualize, understand and approach child mental health.

Keywords: child mental health adhd dna methylation epigenetics sensitive period developmental psychopathology behavioral problems longitudinal modelling child development prenatal environment predictive tools