Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Driving Europe’s NMBP economy - Cross-cluster innovation and value creation through validated NMBP collaborative strategies and roadmap (CLUSTERNANOROAD)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: Coordination and support actions
Countries involved: Germany,Belgium,Belgium,Sweden,France,United Kingdom,Portugal
Call: Networking and sharing best experiences in using regional clusters strategies with a focus on supporting innovation in the NMBP thematic area. (H2020-NMBP-CSA-2016, 2016)
Start date: 2016-09-01
End date: 2019-02-28
Duration (months): 30.0
Total project cost (EUR): 499168.75
EU funding (EUR): 499168.75
Participants: 7
Project status: CLOSED

The CLUSTERNANOROAD project is aimed at developing & implementing effective smart specialization strategies in the field of NMBP aligned with cluster development, thus accelerating differentiation and structural change towards a knowledge-based economy for all European regions.In the proposed CLUSTERNANOROAD project, we will implement evidence-based and deliverable-oriented complementary approaches addressing the key actors belonging and influencing the development of RIS3 strategies supported by cluster and relate framework policies with the ultimate aim of supporting innovation in the NMBP thematic area. This project will consult and mobilise regional authorities, actors through the innovation chain and stakeholders throughout Europe in order to help shape strategic priorities for future regional concerted RIS3/cluster policies at a transregional level, which will intensify cluster and business network collaboration across borders and sectoral boundaries in the NMBP area. By reinforcing cluster and business network cooperation and making them the drivers of implementation, leveraging the experience with cluster policies in Smart Specialisation Strategies and supporting the shaping of concerted RIS3 and cluster policies in a more strategic manner, this action will help to overcome the practical challenges implementing the concept of RIS3 across European regions and will assist SMEs to contribute to the emergence of new value chains and for Europe to take a leading position globally.

Keywords: clusters,regional authorities,more effective ris3 strategies through clusterpilots,cooperation,nmbp focused collaboration and learning platform
Improving Quality of Care in Europe (IQCE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Italy,Germany,Italy,Germany,Switzerland,Belgium,Belgium,Netherlands,Netherlands,Denmark,United Kingdom,Portugal,Denmark,Portugal,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2016, 2016)
Start date: 2017-01-01
End date: 2020-12-31
Duration (months): 48.0
Total project cost (EUR): 3877749.36
EU funding (EUR): 3877749.3600000003
Participants: 20
Project status: CLOSED

Improving quality of care has been given too little attention in health economic research in the past although it is the central goal of health care systems in Europe. The proposed ETN on “Improving Quality of Care in Europe (IQCE)” aims to address this gap and has the following aims: 1) Create new evidence and improve existing health economic research in the field of quality of care. Research gaps are addressed by empirical, theoretical and experimental approaches with a focus on innovative econometric methods using novel access to databases. 2) Establish a close link of the topical PhD projects to health policy and practice ensuring high relevance and practical applicability of results. Implementation of project results can potentially enhance performance of European health care systems. 3) Train PhD fellows to be experts in the field of quality of care and obtain excellent profiles for different career paths in health economic research or practice. 4) contribute to better coordination of currently fragmented health economic research in Europe. This will improve the competitive position of European health economic research. 5) serve as a model for joint doctorate programmes in health economics in Europe. This will drive the development of PhD programmes in health economics in Europe, which currently are scarce. To address these aims, the research programme consists of research clusters: (a) effectiveness & safety, (b) efficiency, (c) access & equitability, and (d) acceptability (WP2-5). Clusters also define secondments and joint research activities of one cluster. Across clusters, scientific training courses, soft-skill-courses and research-in-progress workshops will provide new skills and ensure interaction and exchange between PhD fellows (WP6). The strong participation of the non-academic sector in courses, workshops, acting as hosts, providing research data, or acting as practice mentors for PhD fellows will ensure transfer of research into practice (WP7).

Keywords: health economics,quality of care,effectiveness,efficiency,access to health care,acceptability,competition,regulation,societal value of health and wellbeing
From new Objects to new woRds through GEstures: how sensory-motor experiences of objects and tools influence word acquisition in children (FORGE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-02-01
End date: 2018-01-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

A key question in language studies is how children learn the meaning of new words and corresponding concepts. Developmental studies show that children’s actions promote learning about new objects and that acting on objects is closely related to early gestures’ production, which in turn accompanies vocabulary acquisition. Brain imaging studies have found activation of motor areas when people process action-related words. Together, these findings suggest a link between sensory-motor experiences, gestures and vocabulary acquisition. But how are these related? One hypothesis is that children’s manipulation of objects promotes their learning of concepts, these concepts then drive the use of iconic gestures rooted in actions with objects, as well as word learning. An alternative hypothesis is that iconic gestures scaffold vocabulary learning because gestures maintain important iconic similarity with the corresponding affordances and actions, while having communicative functions like words: thus emergence of gestures would be precursor to word learning. To-date, correlational data seems to support the first hypothesis, but existing data does not allow to clearly establish the direction of effects. The FORGE project aims to test between these hypotheses, to understand how learning new concepts (mental representations for new manipulatable objects), learning to gesture about these new tools and learning their labels are related to one another. The project uses a multi-disciplinary approach, bringing together traditional video-coding techniques from developmental psychology and psycholinguistics, and new bio-engineering sensor technology for movement analysis. As pre-school children learn new words on a daily basis, and because vocabulary is a strong predictor of academic achievement, establishing optimal conditions for learning to occur is critical to any educational setting. It is further critical to implement programmes assisting children with clinical impairments.

Keywords: child development,vocabulary acquisition,sensory motor skills,language,gestures
The Digital Ludeme Project: Modelling the Evolution of Traditional Games (LUDEME)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Netherlands
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-04-01
End date: 2023-12-31
Duration (months): 69.0
Total project cost (EUR): 1997244.0
EU funding (EUR): 1997244.0
Participants: 1
Project status: SIGNED

The development of games goes hand in hand with the development of human culture. Games offer a rich window of insight into our cultural past, but early examples were rarely documented and our understanding of them is incomplete. While there has been considerable historical research into games and their use as tools of cultural analysis, much is based on the interpretation of partial evidence with little mathematical analysis. This project will use modern computational techniques to help fill these gaps in our knowledge empirically. I will represent games as structured sets of ludemes (units of game-related information), which will allow the full range of traditional strategy games to be modelled in a single software system for the first time. This system will not only model and play games, but will evaluate reconstructions for quality and authenticity, and automatically improve them where possible. This will lay the foundations for a new field of study called digital archaeoludology, which will involve addressing technical challenges that could yield significant benefits in their own right, particularly in artificial intelligence. The ludemic model reveals innate mathematical relationships between games, allowing phylogenetic analysis. This provides a mechanism for creating a family tree/network of traditional games, which could reveal missing links and allow ancestral state reconstruction to shed light on the gaps in our partial knowledge. Locating ludemes culturally provides a mechanism for creating interactive maps that chart the transmission of mathematical ideas across cultures through play. This project seeks to bridge the gap between historical and computational studies of games, to provide greater insight into our understanding of them as cultural artefacts, and to pioneer new tools and techniques for their continued analysis. The aim is to restore and preserve our intangible cultural heritage (of game playing) through the tangible evidence available.

Keywords: general game playing,cultural mapping of traditional and ancient games,strategy learning,transfer and explanation
The (missing) fingerprints of Martian large-scale glaciations (MGFR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-06
End date: 2023-09-05
Duration (months): 24.0
Total project cost (EUR): 184707.84
EU funding (EUR): 164466.35
Participants: 1
Project status: SIGNED

Thousands of valley networks incise the Martian southern hemisphere, evidence that liquid water sculpted the Martian surface billions of years ago. This scenario contrasts starkly with the much colder and drier planet that Mars is nowadays, with frozen water accumulated on the polar caps and hundreds of mid-latitude glacial deposits, all frozen to the ground. In transit between these two climate scenarios, liquid water stability regions would have shifted to warmer, high pressure regions, and water would have accumulated beneath the growing ice masses, providing a stable environment for possible ancient life forms. Geological evidence for this transient period, however, is notoriously missing on Mars. Whereas the motion of glacial masses lubricated by subglacial meltwater (wet-based) produces arresting landscapes showing extensive linear substrate scouring on Earth, similar large-scale linear features are missing on Mars, leading to the historical interpretation that Martian ice masses were always frozen to the ground. The project presented here aims to revisit this idea adapting the physical framework describing terrestrial glacial hydrology to Mars, to show that the lower Martian surface gravity affects the dynamics of wet-based glaciers by favoring the emplacement of efficient meltwater subglacial drainage conduits, limiting ice sliding velocity, and producing different erosional fingerprints. Using mathematical models, analogue experiments, and geomorphological comparisons between Martian and terrestrial landforms, my objective is to show that the fingerprints of wet-based glaciation on Mars may be fundamentally different from those on Earth, challenging the current view and raising the possibility of a period of water stability under ancient Martian ice sheets. This project will help guide the search for ancient environments on Mars where water would have been stable, and where life could have existed shielded from the surface for extended periods of time.

Keywords: planetary science,mars surface processes,geomorphology,glacial hydrology
European Circular Energy-Frontier Collider Study (EuroCirCol)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Spain,Spain,Italy,Switzerland,Switzerland,Finland,France,Netherlands,United Kingdom,United Kingdom,United Kingdom,Japan,United Kingdom
Call: Design studies (H2020-INFRADEV-1-2014-1, 2014)
Start date: 2015-06-01
End date: 2019-12-31
Duration (months): 55.0
Total project cost (EUR): 3989842.0
EU funding (EUR): 2999000.0
Participants: 19
Project status: CLOSED

The award of the 2013 Nobel Prize for Physics acknowledged the leading role of Europe in particle physics, which has a global community of over 10,000 scientists. To reinforce its pole position throughout the 21st century, Europe must be ready to propose an ambitious post-LHC accelerator project by 2018/19. This is one of the main recommendations of the updated European Strategy for Particle Physics, adopted by the CERN Council in May 2013. The EuroCirCol conceptual design study is a direct response to this recommendation, initiating a study for a 100 TeV energy-frontier circular collider through a collaboration of institutes and universities worldwide. A new research infrastructure of such scale depends on the feasibility of key technologies pushed beyond current state of the art. Innovative designs for accelerator magnets to achieve high-quality fields up to 16 T and for a cryogenic beam vacuum system to cope with unprecedented synchrotron light power are required. The effects of colliding two 50 TeV beams must be mastered to meet the physics research requirements. Advanced energy efficiency, reliability and cost effectiveness are key factors to build and operate such an accelerator within realistic time scale and cost. This proposal is part of the Future Circular Collider study under European leadership, federating resources worldwide to assess the merits of different post-LHC accelerator scenarios. It forms the core of a globally coordinated strategy of converging activities, involving participants from the ERA and beyond. Organisations joining this study from Japan and the USA are expected to take part in a global implementation project and a suitable governance model will be drawn-up accordingly. The main outcome of EuroCirCol will be laying the foundation of subsequent infrastructure development actions that will strengthen the ERA as a focal point of global research cooperation and as a leader in frontier knowledge and technologies over the next decades.

Keywords: particle physics,accelerators,research infrastructure,international collaboration
Geometric Reconstruction And noVel semantIc reunificaTion of culturAl heriTage objEcts (GRAVITATE)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Reflective societies - cultural heritage and European identity
Action type: Research and Innovation actions
Countries involved: Israel,Italy,Cyprus,Netherlands,United Kingdom,United Kingdom
Call: Advanced 3D modelling for accessing and understanding European cultural assets (H2020-REFLECTIVE-7-2014, 2014)
Start date: 2015-06-01
End date: 2018-11-30
Duration (months): 42.0
Total project cost (EUR): 2593440.0
EU funding (EUR): 2593440.0
Participants: 8
Project status: CLOSED

The overall objectives of the GRAVITATE project are to create a set of software tools that will allow archaeologists and curators to reconstruct shattered or broken cultural objects, to identify and re-unify parts of a cultural object that has been separated across collections and to recognise associations between cultural artefacts that will allow new knowledge and understanding of past societies to be inferred. The project involves, as partners, a world-renowned museum, an archaeology institute, and research partners working in the manipulation of 3-D objects, semantic analysis and ICT integration. The project is driven by the needs of the archaeological institutes, exemplified by a pertinent use case, the Salamis collection shared between Cyprus and the British Museum. Expertise in 3-D scanning from previous project experience enables the partners to embark on a programme of geometrical feature extraction and matching on the one hand, and semantic annotation and matching on the other. The integration of these approaches into a single decision support platform, with a full suite of visualisation tools will provide a unique resource for the cultural heritage research community. We anticipate that the insights to be gained from the use of these tools will lead to faster and more accurate reconstruction of cultural heritage objects for study and exhibition, to greater opportunities for reunification of objects between collections and greater insights into relationships between past societies which can be communicated as coherent narratives to the public through new forms of virtual and tangible displays, involving the reconstructed objects themselves as well as 3-D printed objects and digital visualisations.

Keywords: semantic mapping,geometric matching,3d visualisation,metadata,museum artifacts
NIPBL and Integrator function and dysfunction in human cortical development (NINTCORDEV)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-01
End date: 2020-08-21
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

Development of the cortex requires intricate orchestration of progenitor self-renewal and neuronal differentiation, subtype specification, migration and integration in neuronal circuits. Disturbance of any of these processes has been linked to a variety of developmental disorders, including Cornelia de Lange Syndrome (CdLS). CdLS is highlighted by intellectual disability and seizures and most frequently caused by mutations in the cohesin loading factor NIPBL. Our previous work showed that Nipbl interacts with the neuronal transcription factor Zfp609 and the Integrator complex to regulate cortical neuron migration in mouse embryos. Furthermore, INTS1 and INTS8 mutations were recently reported to cause a severe neurodevelopmental syndrome in humans. This proposal aims to identify the human neurodevelopmental defects caused by INTS1 and INTS8 mutations and NIPBL haploinsufficiency and molecularly dissect the affected transcriptional processes. This will be accomplished by creating patient-specific INTS1, INTS8 and NIPBL mutations in human pluripotent stem cell lines, which will be differentiated into neural progenitor cells to assess effects on protein-protein interactions, long-range chromosome contacts and RNApol2 pausing and into cerebral organoids to assess the impact on different aspects of the neurodevelopmental program, including progenitor proliferation, neuronal migration and subtype specification.

Keywords: cortical development,cerebral organoids,nipbl,integrator complex,neurodevelopmental disorders,cornelia de lange syndrome,long range gene regulation,rnapol2 pausing
Deciphering Bacteria-induced Morphogenesis and Protection in marine Eukaryotes (MORPHEUS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Germany,Germany,Germany
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-02-01
End date: 2024-01-31
Duration (months): 60.0
Total project cost (EUR): 1498750.0
EU funding (EUR): 627706.75
Participants: 3
Project status: SIGNED

Symbiotic bacteria play critical roles in animal evolution, development and metabolism. The molecular and cellular mechanisms underlying these fundamental interactions, however, are largely unknown. To fill this major knowledge gap, I will establish the bacteria-Hydractinia symbiosis as a new model system to fully characterize key cross-kingdom signalling molecules and response mechanisms. The results of my ERC proposal (MORPHEUS) will lead to ground-breaking insights into molecular drivers of eukaryotic morphogenesis, illuminate the evolutionary history of developmental signals for animals – including humans – and provide new chemical scaffolds with intrinsic biological activities that are urgently needed for drug discovery. The marine colonial hydroid Hydractinia belongs to an early branching metazoan lineage, dating back more than 500 million years. The organism reproduces through a larval stage, which upon perception of yet unidentified bacterial morphogenic signals, produced within marine bacterial biofilms, undergoes transformation into the mature organism. In the absence of the bacterial signals, the larva fails to settle and eventually dies. This fundamental process is the basis of this proposal. Capitalizing from my recent pioneering work, I will address the following pressing research questions: Which bacterial signals ensure larval recruitment and metamorphosis? How are bacterial signalling molecules perceived? How is the system protected against alien species? I will apply an innovative combination of state-of-the-art methodologies developed within the fields of natural product and synthetic organic chemistry, microbiology and molecular biology to pursue an in-depth biochemical analysis of this paradigmatic system. Results of MORPHEUS will be transformative for many scientific branches across biological and chemical disciplines, and directly impact the development of sustainable anti-biofouling and drug discovery strategies.

Keywords: bioorganic chemistry,biosignaling,biosynthesis,molecular biology,natural products,organic synthesis,metabolomics,antimicrobials,metatranscriptomics,secondary metabolites