Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Migration, Affective Geopolitcs and European Democracy in Times of Military Conflicts (MAGnituDe)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Democracy and Governance
Action type: Research and Innovation actions
Countries involved: Sweden,Spain,Slovenia,Lithuania,Ukraine,Finland,Poland,Germany
Call: The interrelation between social, cultural and political identities, as well as the sense of belonging, and democracies (HORIZON-CL2-2024-DEMOCRACY-01, 2024)
Start date: 2025-02-01
End date: 2029-01-31
Duration (months): 48.0
Total project cost (EUR): 2986773.75
EU funding (EUR): 2986773.75
Participants: 9
Project status: SIGNED

The general objective of MAGnituDe is to enhance citizen participation through preventing polarisation and the fragmentation of identities related to mass displacement in response to Russia’s war in Ukraine by utilizing affect as a tool, tapping into the sensuous, emotional, and corporeal dimensions of human experience. MAGnituDe explores the consequences of mass migration caused by Russia’s invasion for European democracy and provides evidence-based strategies to reinvigorate democratic governance in response to the negative social consequences of the war for European societies. MAGnituDe utilises the feminist concept of affective geopolitics to analyse how geopolitical narratives and imaginations shape everyday human encounters through which social, political, and cultural identities get constructed and contested. The project explores human encounters on 3 levels: 1) migrant-state (between forcibly displaced people from Ukraine (FDPs) and street-level bureaucrats); 2) migrant-migrant (between FDPs and migrants from Belarus, Russia, and Syria), and 3) migrant-host societies (FDPs encounters with the material culture of host societies). To study the affective dimension of human encounters and identities and to suggest attuned political interventions fostering democratic participation in the sensitive context of the war, MAGnituDe develops and implements an innovative affect-centred methodological framework based on SensArticulate methods, encompassing art-based, experiential, and embodied techniques. MAGnituDe advances an innovative methodology for comprehensive analysis of the interrelations between social, cultural, and political identities, as well as the sense of belonging, and democracies (EO1), which will be used to formulate policy recommendations and pilot strategies preventing discrimination, alienation and marginalisation (EO2) and to diffuse antagonistic identities and social norms (EO3).

Keywords: affect,belonging,citizenship,conviviality,democratic participation,dialogue,geopolitics,identity,memory,war
Cosmological phase transitions of Standard Model Matter and their gravitational wave signatures (CoStaMM)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Hungary
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1839769.0
EU funding (EUR): 1839769.0
Participants: 2
Project status: SIGNED

The Standard Model of particle physics is the theory of the strong, electromagnetic and weak interactions, describing the elementary particles of nature at microscopic length scales. The precise theoretical predictions of the Standard Model are put to the test in contemporary and future high-energy particle collider experiments. Besides explaining matter around us in the present, the Standard Model also predicts the distant past of our Universe, by describing the behavior of particles at temperatures as high as it used to be just fractions of seconds after the Big Bang. The relics of the cosmological phase transitions in this era of our Universe are actively sought for via their gravitational wave signatures in current and future observatories. Most of the relevant features of hot Standard Model matter are non-perturbative, implying that a first-principles treatment is only possible via computer simulations of the underlying field theories on space-time lattices. This proposal will use such large-scale lattice field theory simulations to determine the properties of cosmological phase transitions and thus significantly improve our understanding of how the early Universe cooled down and became the world that we know today. Specifically, we will perform the first full physical simulations of hot, electrically charged strongly interacting matter. We will also substantially improve on existing calculations of the weak and electromagnetic interactions at high temperature. The computational effort of the combined treatment of these forces is immense – we will overcome these challenges by employing optimized algorithms and cutting-edge technologies including machine learning methods. For both systems, we will determine the nature of the high-temperature transition and analyze the induced gravitational wave spectrum. Our results will provide the most accurate description of Standard Model matter in the early Universe.

Keywords: quantum field theory,lattice gauge theory,lattice quantum chromodynamics,thermal field theory,phase transitions and critical phenomena,monte carlo algorithms,high performance computing,cosmological phase transitions
Cost-reduction of EV fast-charging station to enable large-scale electrification of mobility (E2GO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Netherlands,Poland,Portugal,Denmark,Austria
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 2821053.26
EU funding (EUR): 2370903.6
Participants: 12
Project status: SIGNED

Road traffic is responsible for 21% of total EU greenhouse gas emissions and is the main cause of air pollution in urban areas. There is an urgent need to decarbonize transport. The EU aims to ban the sale of new vehicles with an internal combustion engine from 2035 onward. The emerging alternative is battery electric vehicles (EVs). The widespread adoption of EVs requires large investments in charging infrastructure. The electricity consumption of charging EVs puts great pressure on the electric grid. To manage the load in the grid and ensure that peak demand can continue to be met, battery storage may be added to fast-charging stations. Increasing the amount of battery buffers furthermore facilitates the integration of electricity from intermittent renewable sources like wind and sun, leading to faster decarbonization on the electricity supply side. Battery buffers, however, come at a cost. The required power conversions result in losses that increase with the rise in power. Furthermore, there are several key components in fast-charging infrastructure that, through inefficiencies or high price levels, have a high impact on the costs of this equipment. This project sets out to create a doctoral network in which academia and leading actors in the e-mobility sphere co-operate to facilitate nine early-stage researchers to study power electronics, battery storage, cooling, and materials technologies. The goal is to reduce the costs of battery-buffered fast-charging stations by 20% through innovations in system architectures, key components, and multifunctional services. This will assist in managing the load of the grid, e.g. through control mechanisms or vehicle to grid services, and provide a cost-effective way for the large-scale electrification of the mobility sector. The project brings together the entire value chain of fast-charging equipment, enabling the early-stage researchers to access to state of the art equipment and lab facilities to perform their research.

Keywords: ev fast charging,battery buffers,power electronics
From reservoirs to vectors: role of amoebae in antibiotic resistance gene transfer and aquatic microbial dynamics under global environmental factors (FLUXARG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-02
End date: 2027-06-01
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 1
Project status: SIGNED

Antimicrobial resistance (AMR) has become a global threat and a major public health priority under the “One Health” approach. In particular, Aquatic environments affected by anthropogenic activities, represent a huge reservoir and potential hotspot for the spread of antibiotic resistance genes (ARGs), potentially via horizontal gene transfer (HGT) involving mobile genetic elements (MGEs). Current data suggests that free-living amoebae (FLA), which are often underestimated, could play a potential key role in the spread of AMR. FLA not only act as natural predators of bacteria but also serve as protective hosts for various pathogens, enhancing their survival and potential for HGT. Previous studies have shown that FLA are reservoirs for pathogenic bacteria and ARGs of major clinical interest. However, their exact role in the ARGs dissemination via HGT and the involvement of MGEs in this process remains poorly explored. The project FLUXARG aims to further investigate the role of amoebae as reservoirs of ARGs and their contribution to the transmission of ARGs in aquatic environments. By studying HGT between bacteria living in amoebae, we aim to understand how ARGs are spread in aquatic environments via FLA. In addition, FLUXARG will investigate the effect of abiotic factors, such as physicochemical parameters during seasonal variations, on the efficiency of HGT between intra-amoebic bacteria. In parallel, FLUXARG will assess how these interactions shape the composition and diversity of aquatic and amoebic microbiomes, leading to a better understanding of their ecological importance. To achieve these objectives, in FLUXARG, I will employ culture assays, high-throughput genomic and metagenomic techniques, and experimental microcosms to mimicking environmental conditions. The results will lead to a better understanding of the role of FLA in the persistence and spread of AMR, potentially guiding the development of effective strategies to mitigate this growing threat.

Keywords: environmental microbiology antimicrobial resistance horizontal gene transfer antibiotic resistance genes mobile genetic elements free living amoebae bacteria interaction wastewater treatment
Tau, a molecular modulator of neuronal energy managment (EnergizeTau)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-07-01
End date: 2029-06-30
Duration (months): 60.0
Total project cost (EUR): 2194940.0
EU funding (EUR): 2194940.0
Participants: 1
Project status: SIGNED

The intraneuronal somatodendritic "missorting" and aggregation of Tau are pathological hallmarks in neurodegenerative diseases (NDDs) like and Alzheimer's disease (AD), and are thought to be drivers of neurotoxicity. That NDDs manifesting with Tau "missorting" present with (neuro)metabolic abnormalities, often prior to pathology onset, is largely overlooked. EnergizeTau investigates the ground-breaking new idea that the somatodendritic re-sorting of Tau is a physiological response to bioenergetic challenges faced by excitatory neurons, such as hyperexcitation or energy deprivation. In its proposed role as modulator of neuronal energy management, Tau modulates the cellular energy demand through molecular interactions with key cellular functions, e.g., synaptic activity, ATP production and protein translation, and alters the neuronal metabolism. Continued energetic stress in disease results in irreversible "silencing" and Tau aggregation in affected neurons. Using my uniquely broad Tau expertise, we decipher how Tau interferes with energy demanding cellular functions to modulate neuronal energy household downstream of bioenergetic stress. Light-induced Tau expression and CRISPR-edited human neurons enable to study Tau's molecular actions by interactomics and single-molecule imaging, and the effects on cellular functions. Tau's influence on the neuronal metabolism is determined by longitudinal live cell metabolite imaging and spatial transcriptomics in human brains, and the impact on gene and chromatin regulation by Cut&Tag and DNA-FISH. Whether stressors converge on energy limitation as a driver of Tau re-sorting is assessed by high-content metabolite imaging. EnergizeTau introduces the metabolic component of Tau (patho)biology and generates a paradigm shift in NDD research. It creates space for re-thinking hallmark protein pathology in NDDs, and has the potential to result in new approaches targeting the neuronal energy metabolism to prevent and treat NDDs.

Keywords: alzheimer s disease,tauopathies,tau,protein interactions,metabolism
The role of shared micromobility modes in the resilience of urban transportation systems: New challenges and opportunities (ROMSUR)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Czechia
Call: Fostering balanced brain circulation – ERA Fellowships (HORIZON-WIDERA-2022-TALENTS-04, 2022)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 166278.72
EU funding (EUR): 166278.72
Participants: 1
Project status: CLOSED

Increasing urban traffic and environmental challenges have driven the investigation, development, and diversification of sustainable transportation alternatives globally. The resilience of these alternatives has also been considered equally important in recent research in order to ensure a more safe, accessible, and equitable transportation system during severe disruptions. However, there is a lack of comprehensive evaluation system through which urban and transportation planners can assess and plan for transport resilience in their own geographical contexts. In this regard, this research proposes a model to evaluate an overall resilience of shared micromobillity systems through their commonly available usage patterns in light of current challenges and future opportunities. Specifically, it takes major shared micromobillity programs (e.g., station-based bike-sharing (SBBS), free-floating bike-sharing (FFBS), free-floating e-bike sharing (FFEBS), and free-floating e-scooter sharing (FFESS)) operating in Europe as examples to empirically analyze the mobility patterns of their users across three timescales: before, during, and after the pandemic. As a methodology, this study will utilize a combination of quantitative and qualitative techniques. The expected outcomes will help in improving governance and an appropriate appraisal of sustainable urban transport alternatives, which are still in its infancy. The resilience assessment tool will further help develop long-term systems for measuring and executing mobility plans on both sides of the mobility equation: supply and demand.

Keywords: shared micromobility transport resilience mobility as a service urban sustainable active mobility covid 19 europe
Unified theory for water availability impacts on mature tree water use and wood cell formation in forest stems (STEMCELL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth System Science
Panel description: Physical geography, geo logy, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Trees play a key role in regulating the global terrestrial water and carbon cycles by controlling water loss through leaves and directing carbon into stems to form wood. In doing so, forests capture substantial amounts of anthropogenic carbon, a crucial process shaping international climate mitigation policies. However, increasing atmospheric and soil water deficits have raised global concerns about the resilience of wood formation in European forests. Predicting how environmental changes will affect wood formation and related ecosystem services remains difficult due to unclear underlying mechanisms. Recent studies identify turgor as a critical link between tree water-use strategies and wood growth, providing new insights into tree responses to water stress. Before application, this concept must be tested, validated, and integrated into forest growth and carbon models. STEMCELL aims to uncover the relationship between whole-tree water use and wood cell formation in mature trees, using turgor-driven growth models to predict the future of wood formation and carbon allocation in forests facing drier conditions. STEMCELL will integrate experimental, observational, and modelling approaches. Controlled experiments on juvenile trees will be scaled up to mature trees at unique whole-ecosystem rainfall exclusion experiments, carefully monitoring wood formation. These experiments will drive the development of a new numeric model simulating wood formation responses to drought, validated using one of Europe’s largest databases of tree growth, wood structure, and water use. Through the outlined work, STEMCELL will build a solid physiological and mechanistic foundation for predicting the effects of climate change on wood formation and the global carbon cycle. Given the ecological and economic importance of forest ecosystems, the project's outcomes will be critical for guiding science-based forest management and conservation efforts aimed at strengthening ecosystem resilience.

Keywords: mechanistic modelling,carbon allocation,global carbon cycle,forest ecosystems,tree physiology,xylogenesis,drought
PALliative Care Yields Cancer welLbEing Support (PAL-CYCLES)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: Netherlands,Germany,United Kingdom,Hungary,Poland,Romania,Belgium,Portugal,Spain
Call: Improved supportive, palliative, survivorship and end-of-life care of cancer patients (HORIZON-HLTH-2021-DISEASE-04, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 4473958.69
EU funding (EUR): 4473958.0
Participants: 10
Project status: SIGNED

Challenge: many patients with advanced cancer in the final phase of life leave the hospital without continuity of information, and certainty about further treatment and care provision. Often, communication between healthcare providers in different settings is suboptimal and this leads to poor continuity and coordination of care, negatively impacting the quality of life and increasing preventable hospital admissions. Solution: the PAL-CYCLES programme: a transitional palliative care programme for patients with advanced cancer, adaptable to local cultures and healthcare systems. The programme contains an intervention aiming for a smooth transition from hospital care to community care, consisting of five cornerstone components: (1) identification of a patient with palliative and supportive care needs in collaboration with the oncologist and the hospital palliative care team; (2) compassionate communication towards the patient and their family; (3) a collaborative multidimensional care plan and follow-up in the home care setting; (4) periodic evaluation of the care plan with patients and relatives; (5) identification of the terminal phase (if there) based on the periodic evaluations, with appropriate intensification of care and end-of-life talks depending on local possibilities and habits, including consultation with patient and families about ethically and legally sensitive issues. Plan: we intend to develop, adapt, implement, and evaluate the PAL-CYCLES programme in seven European countries using a stepped wedge randomized controlled trial design. Patient, relatives, and health care provider experiences, as well as ethical and equity issues will be addressed with qualitative methods. Impact: the PAL-CYCLES programme will facilitate patient-centred communication and continuity of palliative cancer care in the community care setting, reducing unplanned hospital admissions and improving quality of life for patients with advanced cancer at the end of life.

Keywords: palliative care transitional care communication
Land-based Automated Recirculating Aquaculture (LARA)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Austria
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-05-01
End date: 2025-08-31
Duration (months): 28.0
Total project cost (EUR): 6500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

In order to improve food security and climate resilience, Blue Planet Ecosystems (BPE) aims to decouple the production of animal protein from the ocean by turning sunlight into seafood. It is the companies vision is to establish large-scale, autonomous aquaculture operations in deserts and urban environments with no environmental impact on a scale that is able to feed cities and countries.

Keywords: automation,engineering and technology,energy systems production,distribution,applicat,industrial bioengineering,machine learning,statistical data processing and