Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
ECOFER: Next Generation Slag and Mineral Processing Technology (ECOFER)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Estonia
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Steelmaking is one of the most important and energy intensive industries globally. Until now the repurposing of steelmaking slag, the main production by-product, has remained low-value, incomplete and has an enormous environmental impact. Ecofer, an Estonian cleantech company, has developed next generation slag processing technology, which processes the steelmaking slag completely and increases the value slag over 20 times. This is achieved by recovering 99% of Fe-metal, and providing first technology to separating metal oxides and heavy metals from the slag. The technology is based on proprietary and cutting-edge screening, crushing, milling, fractioning and magnetic separation processes. The technology will generate new growth and market opportunities for the steelmaking industry, as the low-value of steelmaking slag has been a major industry pain-point for decades. Moreover, Ecofer technology directly supports the lowering CO2 emissions – each ton of repurposed steelmaking slag saves one in ton of CO2 emission, reduces the need for virgin material and provides technology for zero-waste steelmaking. Ecofer already signed piloting and commercial pre-agreements with large-scale steel-mills from Europe and Middle-East. During the feasibility study Ecofer will: • Update the route-to-market strategy and business plan; • Conduct a freedom-to-operate study; • Conduct pilot line manufacturability study. As a result of the Phase-1 study Ecofer is ready for entering final development and market uptake phase, as well fully prepared for SMEI Phase-2.

Keywords: steelmaking,slag,vanadium,zero waste steelmaking,industry by product valorization
Distributional Macroeconomics in the Long and Short Run (DisMaLS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance and management
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-02-01
End date: 2024-01-31
Duration (months): 48.0
Total project cost (EUR): 1598433.0
EU funding (EUR): 1598433.0
Participants: 1
Project status: SIGNED

A key development in the “dismal science” has been the incorporation of explicit heterogeneity into models of the macroeconomy. As a result of taking micro data seriously, these theories study macroeconomic questions in terms of distributions of microeconomic variables like income or wealth rather than just aggregates. This approach opens up the door to examining the distributional implications of macroeconomic trends, shocks or policies, and to examine the two-way interaction between these distributions and the macroeconomy. DisMaLS will advance this “distributional macroeconomics” agenda both theoretically and empirically. Theoretically, it will do so by developing new theories of the income and wealth distributions and their interactions with the macroeconomy in both the long and short run. Empirically, DisMaLS will bring to the table high-quality Norwegian administrative data to discipline and enrich these theories. In terms of long-run trends, a striking feature regarding economic growth in many developed countries is that it has been unequally distributed. For example, in the U.S., real household incomes have grown by roughly two percent per year on average but income percentiles corresponding to the bottom 50% of the distribution have stagnated since the 1970s. DisMaLS will use its theory of income and wealth distribution to examine the potential drivers of these distributional trends, for example automation and tax policy. Turning to the short-run, DisMaLS aims to understand the causes of infrequent but large economic crises, like the Great Recession. I aim to develop a quantitative macroeconomic theory that incorporates asset price booms driven by individuals switching out of liquid assets to buy real or illiquid financial assets, and crashes driven by the reverse movement. As part of the project, I aim to develop a new methodology for solving heterogeneous agent models with aggregate risk and both micro and macro non-linearities.
COncurrent METAmaterial-Structure design using functionally graded metamaterials (CoMetaS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Spain,France,France,United States,United Kingdom
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2020, 2020)
Start date: 2021-08-01
End date: 2025-07-31
Duration (months): 48.0
Total project cost (EUR): 924600.0
EU funding (EUR): 924600.0
Participants: 11
Project status: SIGNED

The purpose of CoMetaS is to establish a network of interdisciplinary research groups to solve a new scientific and technological challenge of high practical interest for industry, consisting in developing an integrated, reliable and efficient multiscale methodology for Concurrent Metamaterial-Structure Design employing functionally graded mechanical metamaterials. Taking advantage of the unique technological opportunity that the design freedom revolution of 3D-printing at microscales is bringing to industry and engineering, the purpose of CoMetaS is to help the European industry and future academic system by generating the needed interdisciplinary and intersectoral network of researchers and engineers capable of developing high-tech, value-added products to increase its technological leadership, critical for high living standards in a global market. CoMetaS constitutes a multidisciplinary change of paradigm on how engineering structural design has been performed to date, integrating the metamaterial design concurrently with the structural design through double inverse analyses and surrogate continuum models obtained by data-driven techniques. CoMetaS is a highly multidisciplinary and intersectoral project, involving high-tech companies leading their fields and complementary leading academic research groups. CoMetaS has the right combination of excellence in research, academic training, and industry experience, and high international and intersectoral mobility for fostering innovation-oriented, entrepreneurial, and creative researchers. Through clearly defined research objectives, CoMetaS promotes high mobility, intersectoral, and transnational cooperation for excellent training, science and technology, by involving 6 academic research groups and 4 technological companies from 5 different countries.

Keywords: additive manufacturing,metamaterials,crystal plasticity,continuum mechanics,machine learning,data driven modeling,structural optimization,automobiles,satellites,virtual prototyping
Light-Responsive Adhesives for Debond-on-Demand Solutions (DEGLUMINATE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Switzerland
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-06-01
End date: 2017-05-31
Duration (months): 12.0
Total project cost (EUR): 149250.0
EU funding (EUR): 149250.0
Participants: 1
Project status: CLOSED

Adhesives that debond-on-demand through application of an external stimulus are highly relevant for manufacturing (semiconductor, automotive, aerospace, construction, packaging, sportswear), healthcare applications (wound dressing, transdermal patches), and numerous other domains, and they can significantly contribute to the sustainable use of materials (repairing, reworking, recycling). In all cases, there is a technological need for effective and environmentally benign solutions that provide secure adhesion during use, while also permitting for a simple and clean separation of bonded parts “on command” without the need for additional complex process steps. The proposed project aims to develop new debond-on-demand adhesives based on the combination of low-molecular weight functional polymers and light-responsive degradable cross-linking agents. The new materials are expected to combine optimal adhesive properties for a wide range of substrates with a new mechanism that enables straightforward and efficient, ultraviolet light-induced debonding at ambient temperature. The debonding mechanism involves two different effects that are combined in a synergistic manner: the controlled degradation of the cross-linker transforms polymer networks into low-molecular weight polymers, and the simultaneous release of nitrogen gas “propels” the bonded parts away from each other. The degraded polymer residues can be easily removed and clean debonded components are furnished. The overarching goals of the proposed project are to bridge the gap between scientific discovery and implementation by (i) providing a better understanding for the mechanism at play; (ii) demonstrating the effect in a variety of adhesive platforms based on polymers that are employed in current adhesive technologies; and (iii) providing technology demonstrators for pressure-sensitive adhesive tapes and cold-cured two-component adhesives with debond-on-demand properties.

Keywords: adhesive,light responsive,debond on demand,debonding,pressure sensitive adhesives,adhesive tape,two component adhesive,stimuli responsive
Enantioselective Synthesis of Madangamine Alkaloids via Organocatalytic Desymmetrization (ESOMAVOD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-08-16
End date: 2018-08-15
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

This project will develop a new, highly enantioselective, state-of-the-art synthetic route to madangamine alkaloids B, C and E based on a novel organocatalytic desymmetrization reaction as a key step, which will allow the rapid and efficient construction of the AC rings ready for subsequent advancement to the majority of the family members. Evaluation of the anti-cancer biological activity of the different madangamines and late stage intermediates will be carried out. This Fellowship project combines total synthesis, new asymmetric methodology development via organocatalysis and biological evaluation. This multidisciplinary Fellowship, based on high-quality and novel research at the University of Oxford, one of the top-research centres worldwide, has been designed to augment and complement Dr Vasu’s skills and knowledge to improve his career possibilities and, at the same time, Dr Vasu’s experience in new methodology development and catalysed transformations will be advantageous to the design of the organocatalyst in the key step of the synthesis. The Fellowship will also be useful to establish new collaboration opportunities for the Dixon group. Through the training and the research results arising, the Fellowship will be beneficial to the fellow, the host institution and European science.

Keywords: organic synthesis,catalysis,desymmetrization,total synthesis,enantioselective reactions
Exploring Photon-photon Interactions with Cold Rydberg Atoms (EPICA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2017-09-13
Duration (months): 24.0
Total project cost (EUR): 158121.6
EU funding (EUR): 158121.6
Participants: 1
Project status: CLOSED

The requirements for the basic building blocks of Quantum Information Processing (QIP) are sometimes contradictory: one must seek components that are immune to interactions to preserve their fragile quantum properties, and, at the same time, to have strong, controllable interactions to perform operations on the quantum information they carry. Different implementations using atomic, solid state or photonic systems have different strengths and weaknesses, so there has been a growing interest in the study of hybrid systems, that combine different technologies to implement those basic building blocks. Photons are the best system to transfer quantum information, because they travel very fast (as fast as it is possible) and are virtually immune to losing their quantum properties; however, photon-photon interactions are very weak, and most materials only show nonlinearities at high photon numbers. Recently, it has been shown that Rydberg atoms can mediate strong, controllable interactions between individual photons, thus being an ideal system for QIP tasks. "Exploring Photon-photon Interactions using Cold Rydberg Atoms" (EPICA) is a project aimed at exploring the effective photon-photon interactions mediated by Rydberg atoms. The aims of this project are three: – To combine Rydberg atoms with externally generated single-photons. – To describe in a fundamental way dipole-dipole interactions in the context of multiple stored photons in a highly interacting medium (Rydberg atoms). – To apply this fundamental knowledge to implement basic building blocks for Quantum Information Processing, such as two-photon gates, that could eventually work with single-photons that can be entangled; or others such as a Fock state discriminator or a Fock state emitter.

Keywords: rydberg,photon photon interactions,dlcz,rydberg blockade
Identification of novel inhibitors to prevent microbial production of pro-diabetic metabolites (Drug the bug)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Sweden
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2017-12-01
End date: 2019-05-31
Duration (months): 18.0
Total project cost (EUR): 149700.75
EU funding (EUR): 149700.75
Participants: 1
Project status: CLOSED

The gut microbiota has been associated with metabolic diseases, such as type 2 diabetes. In my ERC consolidator award we demonstrated that the gut microbiota is altered following bariatric surgery and that the altered microbiota may be directly linked to some of the metabolic improvements observed following surgery. Interestingly, improved metabolism was associated with altered metabolite production capacity from the microbiota and we observed that a metabolite, imidazole propionate, was reduced after surgery. In associated projects we have demonstrated that imidazole propionate is associated with type 2 diabetes in humans and induce insulin resistance in primary hepatocytes and when injected into mice. Imidazole propionate is synthesized by the microbial enzyme UrdA from histidine. This POC will explore the potential of identifying inhibitors of UrdA to reduce production of imidazole propionate and thereby improve insulin sensitivity. If successful we envision a new class of diabetes medication based on the concept of drug the bug.

Keywords: gut microbiota,imidazole propionate,enzyme inhibitors,urda,type 2 diabetes,insulin resistance
Brain-Inspired Organic Modular Lab-on-a-Chip for Cell Classification (BIOMORPHIC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-01-01
End date: 2023-12-31
Duration (months): 60.0
Total project cost (EUR): 1498726.0
EU funding (EUR): 1498726.0
Participants: 1
Project status: SIGNED

Brain-inspired (neuromorphic) computing has recently demonstrated advancements in pattern and image recognition as well as classification of unstructured (big) data. However, the volatility and energy required for neuromorphic devices presented to date significantly complicate the path to achieve the interconnectivity and efficiency of the brain. In previous work, recently published in Nature Materials, the PI has demonstrated a low-cost solution to these drawbacks: an organic artificial synapse as a building-block for organic neuromorphics. The conductance of this single synapse can be accurately tuned by controlled ion injection in the conductive polymer, which could trigger unprecedented low-energy analogue computing. Hence, the major challenge in the largely unexplored field of organic neuromorphics, is to create an interconnected network of these synapses to obtain a true neuromorphic array which will not only be exceptionally pioneering in materials research for neuromorphics and machine-learning, but can also be adopted in a multitude of vital medical research devices. BIOMORPHIC will develop a unique brain-inspired organic lab-on-a-chip in which microfluidics integrated with sensors, collecting characteristics of biological cells, will serve as input to the neuromorphic array. BIOMORPHIC will combine modular microfluidics and machine-learning to develop a novel platform for low-cost lab-on-a-chip devices capable of on-chip cell classification. In particular, BIOMORPHIC will focus on the detection of circulating tumour cells (CTC). Current methods for the detection of cancer are generally invasive, whereas analysing CTCs in blood offers a highly desired alternative. However, accurately detecting and isolating these cells remains a challenge due to their low prevalence and large variability. The strength of neuromorphics precisely lies in finding patterns in such variable data, which will result in a ground-breaking CTC classification lab-on-a-chip.

Keywords: neuromorpic engineering,lab on a chip,organic electronics
Assessing risk and progression of prediabetes and type 2 diabetes to enable disease modification - Sofia ref.: 115881 (RHAPSODY)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Public-private partnerships
Destination: Innovative Medicines Initiative 2
Action type: Research and Innovation actions
Partnership: IMI2 (Art-187)
Countries involved: Germany,Germany,Italy,Germany,Italy,Belgium,Finland,Sweden,Belgium,Switzerland,Switzerland,France,France,France,Netherlands,Netherlands,Netherlands,Denmark,United Kingdom,United Kingdom,United Kingdom,Denmark,United Kingdom
Call: Assessing Risk and Progression of Prediabetes and Type 2 Diabetes to Enable Disease Modification (H2020-JTI-IMI2-2015-03-two-stage, 2015)
Start date: 2016-04-01
End date: 2021-09-30
Duration (months): 66.0
Total project cost (EUR): 18691126.01
EU funding (EUR): 8130000.0
Participants: 30
Project status: CLOSED

The stated goal of RHAPSODY is to define a molecular taxonomy of type 2 diabetes mellitus (T2D) that will support patient segmentation, inform clinical trial design, and the establishment of regulatory paths for the adoption of novel strategies for diabetes prevention and treatment. To address these goals, RHAPSODY will bring together prominent European experts, including the leaders of the diabetes-relevant IMI1 projects to identify, validate and characterize causal biomarkers for T2D subtypes and progression. Our plans are built upon: (a) access to large European cohorts with comprehensive genetic analyses and rich longitudinal clinical and biochemical data and samples; (b) detailed multi-omic maps of key T2D-relevant tissues and organs; (c) large expertise in the development and use of novel genetic, epigenetic, biochemical and physiological experimental approaches; (d) the ability to combine existing and novel data sets through effective data federation and use of these datasets in systems biology approaches towards precision medicine; and (e) expertise in regulatory approval, health economics and patient engagement. These activities will lead to the discovery of novel biomarkers for improved T2D taxonomy, to support development of pharmaceutical activities, and for use in precision medicine to improve health in Europe and worldwide.
Social equity goals in conservation interventions: a system thinking approach to track progress at global level (TRECKQUITY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-19
End date: 2017-10-18
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

The rapid decline of the planet’s biodiversity has prompted governments to adopt an ambitious target to halt the loss of biodiversity and ecosystem services by 2020 through the expansion of protected sites, the Aichi Target 11. Despite this target includes the commitment to reach equitable protected sites that should do no harm local people, we still do not have an adequate way to track progress towards achieving equity in conservation interventions. Global indicators are ineffective in capture the complexity and interactions of multiple factors influencing well-being of local communities. The evidence from case studies at local level show ambiguous conclusions that provide little support for broader scale decision making due to the lack of agreed conceptual understanding and standardized methodologies. The aim of this project is build up an innovative methodological approach to track global achievement of equity in conservation interventions from cases studies. This project employs system thinking methods to conceptualize equity in conservation interventions as a dynamic system. This project will gather the scattered information from multiple datasets and case studies and bring them into this system to simulate their behaviour over time by modelling tools. The project will be hosted by an interdisciplinary group, integrating the methodological expertise on conservation interventions and modelling of the CMEC, with the experience analysing governance regimes and politics issues, economic and livelihoods strategies of IFRO, at the University of Copenhagen. The project will focus on policy relevant analyses, taking advantage of a strong collaboration with the WCMC in UK for communication and implementation of outcomes. The outcomes from this project will comprise the first contribution to tracking our progress on reaching equity in conservation interventions, which is necessary to support critical decision making and actions.

Keywords: equity,people well being,protected sites,aichi target 11,system thinking