Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Sensing and Communication Orchestration Protocols Enhancing Sustainability (SCOPES)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Sweden
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 193643.28
EU funding (EUR): 193643.28
Participants: 2
Project status: SIGNED

Future wireless networks will be the cornerstone of smart cities, providing ubiquitous connectivity to countless devices capable of communicating, sensing, and processing vast amounts of environmental data. These capabilities will enhance urban life by improving safety and sustainability by monitoring energy use, natural hazards, and public health factors while coordinating traffic via precise localization and tracking. While 5G faces challenges with inconsistent connectivity and limited sensing, 6G is poised to overcome these limitations through Integrated Sensing and Communication (ISAC). Cell-free massive multiple-input multiple-output (CF-mMIMO) networks, which eliminate fixed cellular architecture, offer scalable orchestration of access points, significantly enhancing connectivity and sensing capabilities. Yet, the research in network protocols enabling ISAC within CF-mMIMO networks is still in its early stages, requiring a sophisticated approach to harmonize physical layer signal processing with higher-layer access and resource management. SCOPES, leveraging the expertise of the University of Pisa in communication and Chalmers University of Technology in sensing, aims to fill this gap by designing sustainable cross-layer protocols. The project will focus on three key areas: investigating Medium Access Control functions to integrate sensing as a 6G feature; developing energy-efficient resource allocation for ISAC CF-mMIMO networks, and designing a cross-layer protocol to minimise energy consumption while meeting both sensing and communication performance requirements. The outcomes will be validated using open-source simulation tools, supporting future research and driving innovation in sustainable wireless technologies. SCOPES will position the researcher as a pioneer in protocol design and generate interest from the telecom industry for pre-standardisation activities and potential investment in cell-free architecture.

Keywords: cell free massive mimo,integrated sensing and communication,protocol design,resource allocation
The Agency of Transnational Strategic Litigators in Global Governance (TransLitigate)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1470849.0
EU funding (EUR): 1470849.0
Participants: 1
Project status: SIGNED

Litigators feature in a crucial role as we confront the pressing global environmental governance challenges of the 21st Century. They possess an agency which is capable of driving the evolution and implementation of law across national boundaries and at the supranational level. This project proposes to develop a groundbreaking, explanatory model of transnational collaborations among strategic litigators which accounts for their modes of collaboration, how those collaborations affect their agency in controlling the issues in their respective fields, and how they negotiate complex ethical and professional challenges in their work. It proposes to develop this model through the combination of comparative doctrinal research and inductive qualitative socio-legal research across four case studies of strategic litigation: climate change, large-scale land transfers, pollution caused by extractives industries, and species conservation. It pursues the ground-breaking aim of explaining the multi-faceted and complex deliberations among transnational communities of litigators which give rise to and shape the landmark cases transforming environmental governance in diverse national contexts. With this contribution to the sociology of strategic litigators, the project will achieve a break-through in our understanding of how change can be initiated in legal systems to overcome perpetual obstacles and meet our global environmental challenges. It pursues a breakthrough in understanding how litigators drive states and their legal systems to act upon their ability to govern global environmental challenges, given the unlikeliness of it occurring through domestic and international lawmaking alone. In sum, the project aims to develop a groundbreaking model of an innovative type of agency and actor in global governance: the strategic litigator collaborating across borders.

Keywords: transnational law legal mobilization legal opportunity structures transnational social movements strategic litigation public interest litigation climate litigation environmental litigation socio legal studies
Programmable Active Matter (ProMatt)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed Matter Physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Israel
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 1903750.0
EU funding (EUR): 1903750.0
Participants: 1
Project status: SIGNED

Living systems employ cLiving systems employ chemical energy to generate mechanical forces and motion, often resulting in emergent phase transitions that manifest as various spatiotemporal structures. This inherent behavior makes living systems ideal subjects for the study of nonequilibrium thermodynamics. Yet, their complexity impedes our current experimental control of their phase transitions. We propose a novel, simple, and quantitative experimental system to study phase transitions of living matter in a controlled nonequilibrium environment. We create an innovative in-vitro active system using biological components, linking a microtubule motile network to gene circuits that control the system through the local synthesis of building blocks. This will allow us to program the constituent's interactions: type, range, strength, position, and the mechanical properties of the carrying media. We offer to study dynamical phase transitions from two perspectives: (1) Internally driven nonequilibrium phase transitions defined by dynamical or nonreciprocal interactions. (2) Thermal transitions occurring within a nonequilibrium environment. We will establish this system by studying microtubules active flow hydrodynamics and pattern formation driven by gene circuits (Aim 1). We will also program local interactions that defy Newton's third law and study their emergent collective dynamics (Aim 2). Lastly Study phase transition of thermal deformable soft objects mechanically interacting with microtubules flows. (Aim 3). Our innovative approach will yield tools and insights for understanding biomaterial self-organization with broad relevance. It has the potential, in the field of physics to lead to the discovery of novel phase transitions and explain them quantitatively. In biology, it helps uncover the mechanisms behind cell shape maintenance and motility regulation. Moreover, it holds promise for industrial applications, enabling precise transport control within closed reactors.

Keywords: active matter,soft matter,microtubules,molecular motors,active flows,cell free,gene expression,dna nanotechnology,
Phages against MDR Enterococcus faecium (PETRI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Norway,United States
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2028-08-31
Duration (months): 36.0
Total project cost (EUR): 307939.68
EU funding (EUR): 307939.68
Participants: 2
Project status: CLOSED

Due to its multidrug resistance (MDR), Enterococcus faecium (Efm) poses a challenge to the healthcare system and renders most standard antibiotics useless. Bacteriophage (phage) therapy has resurfaced as a treatment strategy for bacterial infections due to increasing antibiotic resistance. Its advantages include specificity, low side effects and production costs, especially when used in combination with standard-of-care antibiotics. Phage therapy has been successful in compassionate use, but its wider implementation is hindered by a lack of knowledge on which antibiotics phages synergize and the mechanisms behind remain elusive. Our project is unique in that it aims to enable the use of conventional antibiotics in MDR Efm through phages. We want to explore which antibiotic classes phages synergize with, which survival strategies Efm uses against phages, and how host factors influence the ability of the antibiotic-phage combination to kill Efm. First, we will investigate phages' interaction with different antibiotic classes against Efm. We will explore the dynamics of phage-antibiotic combinations and whether they are additive, synergistic, or antagonistic. Second, potential phage survival strategies of Efm will be investigated. Additionally, membrane vesicles will be investigated as a potential survival strategy against phages, and their ability to act as a decoy and protect the bacterium from phages will be studied. Third, we will investigate the impact of host factors on the phage-antibiotic killing of Efm, to see whether they can enhance or suppress the phage-antibiotic killing. This approach will provide a deeper understanding of the phages-antibiotic interaction against MDR Efm strains, as well as potential survival systems of Efm which may also shed light on possible mitigation strategies. Overall, this approach has the potential to enable the use of standard-of-care drugs against MDR bacterial infections in general.

Keywords: phages,multi drug resistant,enterococcus faecium,antibiotics
A 360 DEGREES PERSPECTIVE ON THE VALUE OF MUSIC (Music360)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Netherlands,Spain,Portugal,Finland,Ireland,Belgium
Call: Towards a competitive, fair and sustainable European music ecosystem (HORIZON-CL2-2022-HERITAGE-01, 2022)
Start date: 2023-03-01
End date: 2026-02-28
Duration (months): 36.0
Total project cost (EUR): 2995563.23
EU funding (EUR): 2995562.23
Participants: 10
Project status: SIGNED

Background music played in shops, bars, restaurants and other venues contributes to their revenue, increases the well-being of customers, and is an important source of revenue intellectual property rights (IPR) holders of the music. Yet, stakeholders have insufficient insight into the use of background music. Venues lack information about the value of music, collective management Organizations (CMOs) lack information for accurate royalty distribution, creators lack information about the usage of their music and policy makers are in the dark about the social and economic value of music. Our goal is to create a digital platform that collects data about the value of music played in venues for different stakeholders. The Platform collects data at a fine-grained level using fingerprinting technology and combines this with data held by CMOs to make this transparently available to stakeholders in the EU music ecosystem, including, creators, venues and policy makers. With this data, creators will understand the value of music and be able to identify new business opportunities. Venues will be able to assess the value of music for their revenue. Policy makers gain insight into the impact of events in the music ecosystem so that responses to disruptions like the Covid-19 pandemic can be based on data. The consortium consists of five CMOs, two universities, a fingerprinting company, a European lobby company for artists, and a company on ecosystem design. Jointly, their customers cover all relevant stakeholders in the EU music ecosystem. The universities will develop a theory of music value based on real-world experiments with the CMOs and their customers. They will design a distributed architecture for secure collecting and sharing of data together with the fingerprinting company. We develop the Platform in two iterations of 18 months each. We will also design a business model and governance structure for further development and use of the Dashboard after the project completes.

Keywords: background music,value,neighboring right,author right,ecosystem,transparancy,statistics
Credible Inference for Empirical Macroeconomics (CreMac)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2024-10-01
End date: 2029-09-30
Duration (months): 60.0
Total project cost (EUR): 1438705.0
EU funding (EUR): 1438705.0
Participants: 1
Project status: SIGNED

Following the credibility revolution, macroeconomists have sought plausibly exogenous instruments and other sources of variation to identify causal effects. Given the complex nature of the macroeconomy, characterised by simultaneous causality and intemporal dependence, this is a high bar. Thus, in the pursuit of exogenous variation, researchers often use minor sources of variation or subtle features of the data to identify the effects of interest. When the variation exploited is modest, “weak identification” can arise. In practice, this means that estimators are no longer asymptotically normal, so standard techniques for statistical inference – conducting hypothesis tests or constructing confidence intervals – are invalid. While this likely occurs in much empirical research in macroeconomics, few papers acknowledge these issues, partially because there are rarely appealing options to address them. This proposal provides attractive options for researchers to combat weak identification in macroeconometric models. First, it offers the possibility to avoid weak identification in the first place, via novel frameworks to exploit instrumental variables in panel and time series data. These frameworks extract richer information from a given instrument and expand the set of admissible instruments. Next, I provide tools to construct confidence sets for dynamic causal effects, a key object of interest, that are valid regardless of how strong the identifying variation is. Existing approaches produce confidence sets that are conservative – too large. I first consider models identified using instrumental variables, improving both computational burden and performance relative to frontier methods. Finally, I consider models identified using more general sources of variation, and, working identification scheme by scheme, provide performance gains over leading methods for confidence sets. I thus facilitate credible inference to match credible identification strategies.

Keywords: time series econometrics,macroeconometrics,weak identification,weak instruments,instrumental variables,empirical macroeconomics
Evaluating Env-specific antibodies for the diagnosis and treatment of complex human diseases (ENVISAGE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Human endogenous retroviruses (HERV) are highly repetitive sequences that are remnants of viral infections successfully integrated in the genome. Aberrant expression of HERV envelope (Env) proteins is frequent in cancer, autoimmunity, neurodegeneration, and infection and has been associated with antibody responses. However, we do not know if all HERV Env proteins contribute to antibody responses or what the prognostic impact of HERV Env-specific antibodies is. Thus, the objectives of this proposal are to i) implement a high-throughput screening platform for HERV Env-specific antibodies and ii) develop a bioinformatics approach to identify the HERV insertions producing Env proteins. To achieve these goals, HEK293T cell lines overexpressing 10 different HERV Env proteins will be generated and used to quantify the abundance of Env-specific antibodies in serum from thousands of cancer, autoimmunity, and infection patients. With this work, we will determine if antibody responses to Env proteins are disease-specific and evaluate the impact of sex, age, and ethnicity on Env antibody titres. Following this, we will build a pangenome reference of HERV sequences in the human population to evaluate the polymorphism of HERV insertions. This database of HERV insertions will be used in combination with highly targeted sequencing (Amplicon-seq) and epigenomics to precisely identify the HERV insertions that are active in pathologies and produce Env proteins. Finally, we will analyse publicly available datasets to evaluate the impact of HERV Env expression on disease progression and survival. In addition to deepening our understanding of several human pathologies, this work could have important impacts on the diagnosis and treatment of complex human diseases.t

Keywords: human endogenous retroviruses,humoral immunity,autoimmunity,cancer,infection
Development and Application of Ultrafast Low-Energy Electron Microscopy (ULEEM)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 2488216.0
EU funding (EUR): 2488216.0
Participants: 1
Project status: SIGNED

This proposal aims at the development and application of Ultrafast Low-Energy Electron Microscopy (ULEEM), a new experimental technique for studying dynamics at surfaces. It addresses a key question in ultrafast surface science, namely the observation of rapid structural changes with high spatial and temporal resolution, and with ultimate surface sensitivity down to the monolayer level. In order to achieve this goal, a number of conceptual and technological challenges will need to be addressed. This project is designed to support a comprehensive approach to the successful implementation of ULEEM. Pulsed electron source concepts and electron pulse compression schemes will be realized for the conditions of low-energy electron microscopy. Furthermore, tailored contrast mechanisms will be employed to enhance the time-resolved mapping of specific structural features and domains. With this newly established methodology, we will study a selected set of model systems and nonequilibrium phenomena to explore ultrafast surface imaging of the dynamics and control of phase transformations, interlayer energy transfer in van der Waals heterostructures, and the excitation and propagation of collective modes.

Keywords: ultrafast dynamics at surfaces,2d heterostructures,ultrafast electron microscopy and diffraction,metastable states,ultrafast phase transitions
BIOBASED BUILDING BLOCKS FROM BIOREFINERY FOR SAFE DIAMOND-LIKE AND BIOPOLYURETHANE COATING SOLUTIONS UNDER EXTREME AND DEMANDING CONDITIONS OF USE AND END OF LIFE - BIO4COAT (BIO4COAT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Public-private partnerships
Destination: Circular Bio-based Europe
Action type: Research and Innovation actions
Partnership: CBE (JU-JTI)
Countries involved: Spain,Italy,Germany,Portugal,Denmark,Greece
Call: SSbD bio-based coating materials for applications under demanding and/or extreme conditions (HORIZON-JU-CBE-2024, 2024)
Start date: 2025-06-01
End date: 2029-05-31
Duration (months): 48.0
Total project cost (EUR): 3493570.0
EU funding (EUR): 3493570.0
Participants: 10
Project status: SIGNED

BIO4COAT aims to validate at TRL 5 the use of 3 biobased building blocks (1,4-bioBDO, lcDCA, and biomethane) from Novamont’s biorefinery for producing safe and sustainable biobased coating solutions. Two value chains are planned: (1) Novamont will supply first-of-their kind polyester-polyols from 1,4-bioBDO and lcDCA for conversion into polyurethanes by FUNDITEC, to be used to create 1K PUD and 2K PUR in 7 prototypes under the guidance of ICAP-SIRA; (2) Aarhus University will purify biomethane for use by CEMECON in creating DLC coatings via CVD for high-temperature plastic processing tools, validated by LOGOPLASTE. Performance will be tested in terms of surface protection, printability, and controlled release under demanding conditions, with added recyclability, compostability, and no bioaccumulation, across 8 sectors (plastics, hygiene, textiles, agriculture, horticulture, furniture, energy, and construction). CERTH will implement a comprehensive SSbD methodology, guiding the development of biobased coatings with reduce (-20%) GHG emissions, allowing multiple EoL scenarios, and minimizing bioaccumulation risks. Upscaling insights(aligned with the CBE-JU TERRIFIC project), feasibility analyses, and business models will be supported by the University of Padua. KNEIA’s dissemination, exploitation, and communication efforts will maximize the visibility and impact of project outcomes. The analysis and engagement of stakeholder and the clustering activities will be performed at 2 levels: along the overall value chain by KNEIA, and with a focus on technical actors by EUBP which will establish 2 technical working groups with other EU-funded projects. Key impacts are expected in long-term progress in bio-based materials science and engineering, cost savings for industries by 30%, increased biodiversity and environmental health due to reduced pollution and sustainable resource use, expansion of the market for bio-based coatings, and enhanced competitiveness of EU SMEs