Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Twinning for the advancement of data-driven multidisciplinary research into hydro-climatic extremes to support risk assessment and decision making (EXtremeClimTwin)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Germany,Norway,Serbia,United Kingdom
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2020-11-01
End date: 2023-10-31
Duration (months): 36.0
Total project cost (EUR): 889336.25
EU funding (EUR): 889336.25
Participants: 4
Project status: SIGNED

EXtremeClimTwin aims to strengthen and improve the research and innovation capacity of the Faculty of Science, University of Novi Sad (UNSPMF; Novi Sad, Serbia) in the areas of climate change and hydro-climate extremes through twinning with internationally-leading counterparts from Member States of the EU: the SME and research company Climate Risk Analysis (CRA, Germany) and Loughborough University (LU, United Kingdom) and Associated country the Center for International Climate research (CICERO, Norway). It is expected that a warmer climate will result in a higher incidence of heat waves, less summer precipitation and at the same time higher rainfall intensities throughout much of South East Europe. Increasing heat extremes are a key hazard in this part of Europe. Together with reduced summer precipitation, they can increase drought risk, health risks and energy demand in summer. However, there is a knowledge gap in this part of Europe to properly understand how climate change will continue to affect the region. Cold waves, heatwaves and droughts in the summer, put a strain on the health system and the economy. Therefore, UNSPMF recognized the need to build capacities in detection and attribution of extreme hydro-climate events through collaborations and training with institutions that examine these events in other parts of Europe. The close collaboration between researches from UNSPMF and other experts in the field of climate change and hydro-climate extremes in the EU will form a synergistic network that will permit the transfer of knowledge and training of the existing personnel and early stage researchers of UNSPMF. As a result, the EXtremeClimTwin will have both direct and indirect scientific, social and economic impacts. In addition, the implementation of the project will facilitate future collaborations with experts in the field at EU level, increase the UNSPMF research capabilities, as well as enhance the research and academic profile of all participants.

Keywords: climate change,temperatures extremes,hydro climate extremes,statistical anaysis
Training of Innovative, Creative and Entrepreneurial Researchers in Waterborne Dispersed Polymers (TRACKWAY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Spain
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-EID) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 754634.16
EU funding (EUR): 754634.1599999999
Participants: 2
Project status: CLOSED

TRACKWAY aims at training the next generation of creative, entrepreneurial and innovative researchers combining projects at the frontline of the research in functional dispersed polymers with interdisciplinary training in transferable and specialized skills. Based on the synergetic collaboration between BASF, a leading industry in dispersed polymers and University of the Basque Country, a reputed academic institution in the field, the research programme faces the challenge of innovation aiming at creating new waterborne dispersed polymers with new functionalities and lower environmental impact. In particular, it aims at developing intrinsically autonomous self-healing coatings, waterborne adhesives with controlled temperature responsiveness, and non-leaching exterior coatings that will avoid the long-term environmental concern caused by the leaching of surfactants from roofs and facades. The research program is complemented with training in basic and industrially-relevant transferable skills and with exposure of the young researchers to different environments and ways of thinking beyond the consortium. The young researchers trained in this interdisciplinary and intersectorial programme will be able to face the challenge of converting knowledge into useful, marketable and sustainable products, which will make them highly valuable by the large EU industry in this field as well as for many other industrial sectors and academia.

Keywords: waterborne polymers,self healing coatings,temperature sensitive adhesives,alkali soluble resins,controlled radical polymerization
Véhicule Intelligent et Propre ( Green and Smart Vehicle) (VIP)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: France
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2017-10-01
End date: 2020-03-31
Duration (months): 30.0
Total project cost (EUR): 1690162.5
EU funding (EUR): 1182238.75
Participants: 1
Project status: CLOSED

VIP project objective is to develop, at an industrial level, a fuel quality sensor solution to be installed on-board vehicles for CO2 reduction. At a time when all eyes are turning to alternative, carbon-free methods of propulsion, technology related to electric batteries and fuel cells are at the forefront when it comes to the means of producing or storing energy. However, the duration of the transition phase should not be underestimated - when existing technology and thermal engines are improved. The thermal engine is, and will remain for these next 30 years, the best way of moving vehicles. This means there is a part that must be dealt with urgently: the CLEAN thermal vehicle during this long transitional phase. Europe and the world's leading jurisdictions are advocating and legislatively pushing for the adoption and widespread use of renewable fuels, which promote the circular economy and short circuits. These new fuels operate in traditional "drop in fuel" engines (i.e. up to 100%) by offering a reduction in CO2 of up to 90% compared to a conventional gasoline or diesel fossil fuel on the complete Well to Wheel cycle. It is therefore the strengthening of legislation and taxation based on CO2 and pollutant emissions, coupled with a stricter approval process, including a part on vehicle real field use conditions which will lead to the integration and spread of new on-board measurement and control systems, closer to the fuel tank system. This combination of constraints on vehicle approval, the regulatory effort to reduce greenhouse gas emissions combined with the availability on the market of refined renewable fuels in compliance with the RFQ / RED Guidelines on large volumes, opens a real prospect for the integration of a connected fuel quality/CO2 reduction function. Fuel monitoring system also opens the door for automakers for engine/fuel co-optimization allowing to double CO2 saving by reaching up to 10% compared to a standard combustion with fossil fuels.

Keywords: fuel quality impact,fuel sensor,pollutant emissions,wltp,engine optimization,renewable fuels,2nde gen biofuel,transportation
Biological pump Sensitivity and climate change: InterroGatiNg past environmentAL perturbations (BioSIGNAL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France,United States
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-07-01
End date: 2022-08-31
Duration (months): 36.0
Total project cost (EUR): 257619.84
EU funding (EUR): 257619.84
Participants: 2
Project status: CLOSED

The biological pump refers to the mechanism by which carbon is assimilated by photosynthetic algae in the ocean photic zone and subsequently exported to depth upon death of the organisms. The largest part of this export production is generally remineralized as it travels throughout the water column where it depletes dissolved oxygen concentrations. A fraction of the export production may still reach the sea floor, where it is susceptible to be buried, thus inducing a net removal of CO2 from the ocean-atmosphere system. Therefore, the good appraisal of the response of the biological pump to changing environmental conditions is crucial to reasonably predict climate and ocean oxygenation impacts, both associated with past events and as will result from ongoing anthropogenic emissions. However, the behavior of the ecological system in the face of climatic changes and how it impacts the strength and efficiency of the biological pump remains difficult to predict. To address this, here I propose to investigate the sensitivity of the biological pump in a novel way – using a state-of-the-art ecological model including a representation of marine biogeochemical cycles. I will focus on past periods, which provide a whole evolutionary chronicle to which model outputs can be directly compared. Confrontation of model results with geological records will also allow me to develop a mechanistic understanding of the behavior of the ecological system in response to a wide range of environmental perturbations. The proposed approach constitutes an unrivaled opportunity to increase our understanding of the geological record and what it can tell us of relevance to the future. Lessons learned here, both positive and negative, have the potential to help inform the next generation of marine ecosystem models needed to make improved projections of future global change impacts on ocean ecosystems, and hence engaging a broad range of global change scientists and ultimately, policy makers.
The Conformation Of S-phase chroMOSomes (COSMOS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United States,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-02-01
End date: 2024-01-31
Duration (months): 36.0
Total project cost (EUR): 271732.8
EU funding (EUR): 271732.8
Participants: 2
Project status: TERMINATED

DNA replication initiation is strictly regulated to ensure complete genome duplication. In eukaryotes, temporal control of origin firing across chromosomes establishes replication timing domains. Failures in the timing of replication initiation across chromosomes is implicated in DNA replication stress, a hallmark of cancer, but the function of these temporally restricted replication domains is not understood. As well as the duplication of DNA, S-phase involves the duplication of all chromosome structural elements and the complete separation of chromosomal intertwines. How this is achieved is poorly understood. A major hurdle for understanding how 3D chromosomal structures are duplicated in S-phase and inherited through mitosis is that current Hi-C methodologies do not give a distinction between chromatids during or immediately after DNA replication. This project aims to visualise the structure and interactions of replicating chromosomes by developing a new Hi-C method which will allow a separate analysis of each new sister chromatid during its formation. This will provide unique information about how DNA loops and interactions are replicated and resolved, preventing the accumulation of toxic chromosomal defects in each new daughter. This method will then be extended to address the impact of replication stress for the inheritance of chromosome structure. The project will result in a new understanding of the interplay of replication timing, DNA damage and chromosome structure, which may provide a novel framework to understand the causes of chromosomal aberrations that accompany tumour progression.

Keywords: replication origins,hi c,replication stress,b compartments,replication timing domain
Dynamic Agile Production Robots That Learn and Optimise Knowledge and Operations (DARKO)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Germany,Italy,Switzerland,Sweden,United Kingdom
Call: Robotics in Application Areas and Coordination & Support (H2020-ICT-2020-2, 2020)
Start date: 2021-01-01
End date: 2025-06-30
Duration (months): 54.0
Total project cost (EUR): 6997841.25
EU funding (EUR): 6997841.25
Participants: 8
Project status: SIGNED

Agile Production crucially depends on the effectivity of intralogistics processes. Robots as components of these processes have the potential to be a game changer provided they are highly flexible, capable, cost- and energy-efficient, safe and able to operate in work environments shared with humans. However, the current state of the art falls short of providing these capabilities given the requirements for future production systems. Thus, DARKO sets out to realize a new generation of agile production robots that have energy-efficient elastic actuators to execute highly dynamic motions; are able to operate safely within unknown, changing environments; are easy (cost-efficient) to deploy; have predictive planning capabilities to decide for most efficient actions while limiting associated risks; and are aware of humans and their intentions to smoothly and intuitively interact with them. To maximise its impact, DARKO is aligned with use cases at the largest manufacturer of home appliances in Europe. It will demonstrate, in relevant scenarios, autonomous capabilities significantly beyond the current state of the art in dynamic manipulation (e.g., throwing of goods, picking and placing objects while in motion), perception, mapping, risk management, motion planning and human-robot interaction. Beyond its impact through improved capabilities in these areas, DARKO will provide answers to the questions where and how dynamic manipulation should be integrated as the most efficient solution in intralogistics. Since arm manipulators can, in principle, display super-human performance in terms of accuracy and repeatability, the value of integrating dynamic manipulation, e.g. throwing, into transport processes may well exceed current expectations. The DARKO consortium is uniquely placed to tackle this ambitious and challenging project. It brings together leading academic and corporate researchers, technology providers and end-users, with the required long-standing expertise.

Keywords: efficiency
Production of synthetic renewable aviation fuel from CO2 and H2 (TAKE-OFF)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Alternative fuels and mobile energy sources
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Germany,Germany,Belgium,France,France,Netherlands,Netherlands,Denmark
Call: Development of next generation renewable fuel technologies from CO2 and renewable energy (Power and Energy to Renewable Fuels) (H2020-LC-SC3-2020-RES-RIA, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 5340538.75
EU funding (EUR): 4998788.25
Participants: 11
Project status: SIGNED

TAKE-OFF is an industrially driven project that will be a game-changer in the cost effecTAKE-OFF is an industrially driven project that will be a game-changer in the cost effective production of sustainable aviation fuel (SAF) from CO2 and hydrogen. Due to their strict criteria in terms of physical and chemical properties, the aviation sector is highly limited in the number of options for meeting sustainability goals. The unique TAKE-OFF technology is based on conversion of CO2 and H2 to SAF via ethylene as intermediate. The industrial partners SkyNRG (SAF developer) and FEV (power systems) will team up with ground-breaking research groups at CNRS (catalyst development), TNO (reactor and process design), and RWTH (engine out emissions reduction) to deliver a highly innovative process which produces SAF at lower costs, higher energy efficiency and higher carbon efficiency to the crude jet fuel product than the current benchmark Fischer-Tropsch process. The project will further leverage the investments in the ALIGN-CCUS (ERA-NET ACT) project with the involvement of key industrial players in the development of synthetic sustainable fuels. TAKE-OFF’s key industrial players are RWE (power producer), MHPSE (energy technology provider), and AKEU (electrolysis systems), allowing the demonstration of the full technology chain, utilizing industrial captured CO2 and electrolytically produced hydrogen. The demonstration activities will provide valuable data to the University of Southern Denmark for comprehensive technical and economic and environmental analyses with an outlook on Chemical Factories of the Future. The consortium is further supplemented by the leading industry association, CO2 Value Europe, for communication and exploitation. The achievement of the project objectives will contribute directly to the UN Sustainable Development Goals, European Green Deal, and the Renewable Energy Directive II, where sustainable aviation fuels are receiving increased attention.

Keywords: co2 utilization,aviation,renewable fuel,reactor design,catalyst development,synthetic fuel,olefins,green h2,in situ water removal,renewable hydrogen,captured co2
Controlled Autonomous Robot for Early detection and Rehabilitation of Autism and Intellectual Disability (CARER-AID)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-01-09
End date: 2019-01-08
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

This proposal envisions a humanoid robot as a supervised autonomous assistant that will support caregivers in early diagnosis and improve the treatment of individuals with Autism Spectrum Disorder (ASD) associated with Intellectual Disability (ID). The robot can be part of the diagnostic team during the administration of the psycho-diagnostic tests in order to enrich the data that the psychologist can use to refine the diagnosis, helping them to distinguish among the ASD and ID levels. The robot can autonomously carry out routine rehabilitation activities that don’t need particular attention by the human therapist, who can, therefore, focus on other subjects that need more care. The robot will always remain under the ultimate control of the caregiver who can use the robot’s sensors streaming to monitor the child and intervene when needed. The proposal presents a research program that will introduce three main innovations: (i) an unique set of use cases in which a sociall assistive robot gives support to the diagnosis and rehabilitation of ASD and ID; (ii) implementation of novel control strategies for autonomous and safe robot-child interaction that can support the intelligent personalization of activities and overcome problems of the “Wizard of Oz” (WoZ) approach in practical applications; (iii) An user-centred design of the use cases that facilitates the direct integration of the robot in everyday activities and standard therapeutic protocols. The final output of the research project will be a complete set of use cases that will be empirically validated via pilot studies and small-scale trials in school, family and clinical environments. Furthermore, the proposal enlists a series of actions for the widespread scientific dissemination of the experimental results and outreach activities to give evidence also to the general public of the actual opportunities offered by robot and, thus, increase their acceptance and willingness to use robots in the care of ASD and ID.

Keywords: socially assistive robotics
New Chemical Tools for Precision Glycotherapy (GlycoEdit)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2017-11-01
End date: 2023-04-30
Duration (months): 66.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Glycosylation, the expression of carbohydrate structures on proteins and lipids, is found in all the domains of life. The collection of all glycans found on a cell is called the “glycome” which is information rich and a key player in a plethora of physiological and pathological processes. The information that the glycome holds can be written, read and erased by glycosyltransferases, lectins and glycosidases, respectively. The immense structural complexity and the fact that glycan biosynthesis is not under direct genetic control makes it very difficult to study the glycome. The glycosylation pattern of cancer cells is very different from that of healthy cells. It is still unclear whether aberrant glycosylation of cancer cells is a cause or consequence of tumorigenesis but it is associated with aggressive and invasive forms of cancer and hence poor prognosis. Malignant glycans are directly involved in a number of mechanisms that suppress the immune response, increase migration and extravasation (metastasis), block apoptosis and increase resistance to chemotherapy. The aim of this proposal is develop new glycomimetics that can be used to edit the glycome of cancer cells to target such evasive mechanisms. Using combinations of new glycan based inhibitors, a coordinated attack on the cancer glycome can be carried out which is expected to severely cripple the cancers ability to grow and metastasize. This will make the tumor more susceptible to immune mediated killing which may be further enhanced in combination with other anti-cancer strategies. To minimize systemic side effects, new methods for the local delivery/activation of glycan inhibitors will be developed. The developed methods are expected to have a much broader than just cancer alone since the studied mechanisms are also associated with autoimmune and neurodegenerative disease.

Keywords: glycosylation,carbohydrates,chemical biology