Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Scalable, Plug & Play and Modular DC Power Systems for low-emission Large Vessels (ALL-DC-SHIPS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Mobility
Destination: Clean and competitive solutions for all transport modes
Action type: Innovation actions
Partnership: ZEWT (co-programmed)
Countries involved: United Kingdom,Denmark,Austria,Belgium,Germany,Norway,France,Sweden
Call: Demonstrating efficient fully DC electric grids within waterborne transport for large ship applications (ZEWT Partnership) (HORIZON-CL5-2024-D5-01, 2024)
Start date: 2025-02-01
End date: 2028-07-31
Duration (months): 42.0
Total project cost (EUR): 10248808.25
EU funding (EUR): 7499448.25
Participants: 12
Project status: SIGNED

The use of fossil fuels and emission of greenhouse gases (GHG) from waterborne must be minimised as fast as possible to reach a climate-neutral society by 2050. A vital prerequisite of the decarbonisation is the rapid growth of low-carbon power sources and energy storage. To achieve this, the efficient integration in the shipboard power system requires the development of high-power components and protections, and more specifically DC-DC power converters and DC switchgear. Albeit DC primary grids have been deployed for several vessels, the secondary grid has remained substantially identical to traditional solution based on AC. There is an opportunity to unlock the capabilities and functionalities of novel components for secondary grids that can improve the safety and the operations on the vessel. These components, integrated with the power converters and the protections of the primary grids, will reduce the risks of blackouts connected to faults and improve the reliability of the power supply. ALL-DC-SHIPS has devised a comprehensive strategy to address the challenges faced by shipowners, systems integrators and ship operators that includes: 1) development of new modular power converters with wide bandgap devices for primary DC grids 2) high-density power converters for secondary DC grids 3) innovative DC protection systems for primary and secondary DC grids 4) implementation of advanced algorithms for real-time ship energy management 5) rigorous testing and validation methodologies for the vessel demonstrator 6) providing recommendations for relevant use cases above 5,000 GT. ALL-DC-SHIPS will contribute to enable low-emission waterborne transport and technology transition for a resilient and sustainable future of the maritime sector.

Keywords: dc power networks,power control systems,silicon carbide converters
Data and Market Power in the Digital Economy (DMPDE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: France
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-09-01
End date: 2028-08-31
Duration (months): 60.0
Total project cost (EUR): 1287813.0
EU funding (EUR): 1287813.0
Participants: 3
Project status: SIGNED

Improvements in technology are enabling firms to collect and process increasingly large amounts of detailed information about their customers and their competitors. This growing use of data is fundamentally changing the nature of competition. For example, it is affecting i) how firms compete, as they offer collections of services, ii) the level at which firms compete, as they make personalised offers to individual consumers, and iii) the complexity of firms’ strategies, as they increasingly delegate decisions to algorithms. The research in this proposal will deepen our understanding of how data is changing market power, and how this should be reflected in antitrust and competition policy. There are four key themes: 1. Ecosystems. Many online services are grouped together in ecosystems. These services interoperate with each other and share data. The research will examine how data affects the boundaries of ecosystems. It will also analyse the welfare implications of policies that limit how ecosystems can use data. 2. Personalisation. Data can be used to give consumers a personalised experience. The research will look at how the ability to offer personalised products changes competition and efforts to acquire data. The research will also examine how personalisation affects the incentives to engage in anti-competitive practices like predation. 3. Consumer Search. Consumers often need to search in order to learn about firms’ product offerings. The research will explore how a consumer’s search behaviour generates data. It will also examine a firm’s incentive to manipulate the search process in order to learn more about a consumer’s preferences 4. Algorithms. Data is a crucial input into algorithms. The research will examine whether platform algorithms can use certain types of data to prevent sellers from charging less on other sales channels. The research will also investigate whether seller algorithms can autonomously learn anti-competitive behaviours like predation

Keywords: data,multiproduct,ecosystems,personalisation,consumer search,algorithms
The Political Economy of Legal and Governance Reform in Non-Western Societies: Insights from Central Asia (POLCA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Sweden,United Kingdom,Türkiye,Kyrgyzstan,Uzbekistan,Turkmenistan,Tajikistan,Kazakhstan,Japan,Switzerland,Canada,Czechia,Germany,Latvia,Estonia
Call: MSCA Staff Exchanges 2024 (HORIZON-MSCA-2024-SE-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 1753500.0
EU funding (EUR): 1753500.0
Participants: 30
Project status: SIGNED

The overarching objective of POLCA is to contribute to global and national efforts in understanding the challenges of promoting good governance and the rule of law in non-Western societies. This will be achieved by designing and implementing an interdisciplinary research and training program focused on “alternative institutions and norms.” More specifically, POLCA is built around three interconnected goals: 1) To collect original empirical data and produce new theoretical insights on alternative legal and governance institutions and norms in non-Western contexts; 2) To engage with and contribute to relevant theoretical debates within law, development and governance (LDG) studies and political economy literature and thereby advance scholarly discussion on the role of non-Western institutions and norms in legal and governance reform processes; and 3) To contribute to the global law, development and governance agenda by providing strategic intelligence and policy insights for international organisations, development agencies, decision-makers, researchers and practitioners inside and outside the EU on possible ways to improve the rule of law and governance in non-Western societies. These goals will be accomplished through a multi-sited, interdisciplinary, and multisectoral research and staff exchange program involving 30 leading universities and non-academic institutions across Europe, North America, Central Asia, the Middle East and East Asia.

Keywords: political economy decolonization law,development and governance alternative institutions global and transnational governance central asian studies law and society global south
Revolutionizing Mirror Technology to Discover the Dark Universe (MIRRORS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-11-01
End date: 2027-10-31
Duration (months): 60.0
Total project cost (EUR): 2497138.0
EU funding (EUR): 2497138.0
Participants: 1
Project status: SIGNED

The first detection of gravitational waves, and in particular the observation of merging black holes, which otherwise appear 'dark', has been one of the most exciting scientific achievements of the last decades. With the next generation of even more sensitive detectors, we plan to be able to see gravitational waves from objects as far away as the edge of the observable universe. However, a major limitation to the sensitivity of these detectors is the thermal noise of their core components: the highly-reflective coated interferometer mirrors. The use of cryogenic temperatures will be a major step forward in thermal-noise reduction. However, with current coating technology, the sensitivity goals of next generation detectors cannot be met, not to mention further upgrades or future detector generations: (a) All amorphous coating materials, identified so far, with low thermal noise at low temperatures, show too high optical absorption. (b) Single-crystalline coatings can show both low thermal noise and low absorption, but come with different obstacles such as limitations on the size and material combinations, or different noise mechanisms e.g. from bonding the coating to the mirror. I plan to explore a completely new path to realize coating-free mirrors: The use of ion implantation to create a highly-reflective multilayer structure directly inside the silicon mirror substrate. My main hypothesis is that the implantation procedure preserves the excellent optical and thermal-noise properties of crystalline materials, which cannot be met by amorphous coatings, while not imposing the limitations of single-crystalline coatings. A successful realization of such mirrors will solve the coating thermal noise issue in gravitational-wave detection entirely, allowing for an unhindered view into the Universe.

Keywords: mirrors,thermal noise,gravitational waves,precision metrology
LifeMatrix Vascular Graft: A biomimetic Implant for Children with Congenital Heart Disease (LMVG)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Switzerland
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Congenital heart disease (CHD) is the most common congenital defect and the leading cause of death from birth anomalies. In the EU alone, over 36,000 children are born with CHD each year, and one in four requires open-heart surgery within the first year of life. For those with single-ventricle disease, the Fontan procedure is often the only life-saving option, but it relies on vascular grafts made from synthetic or animal-derived materials that cannot grow or remodel. As children grow, these grafts degenerate, causing stenosis, thrombosis and calcification that lead to repeated high-risk surgeries, lifelong complications and high healthcare costs. LifeMatrix Technologies AG, a Swiss deep-tech spin-off from the University of Zurich, has developed a proprietary bioengineering platform that enables the industrial production of biomimetic, human-cell-derived implants capable of remodelling and growth. This scalable platform lays the foundation for a new generation of cardiovascular implants that transform into living tissue after implantation. The first product derived from this platform, the LifeMatrix Vascular Graft (LMVG), targets the urgent unmet need in paediatric CHD. Designed as an off-the-shelf, acellular graft composed of human extracellular matrix and biodegradable polymers, the LMVG remodels into native-like tissue, providing a safe and potentially lifelong solution. The technology has reached TRL6 and is GMP-ready for First-in-Human evaluation. EIC support will enable clinical validation, CE-marking and European scale-up, accelerating market entry and securing Europe’s leadership in regenerative cardiovascular medicine. With its multidisciplinary team and clinical partnerships already in place, LifeMatrix is ready to transform care for thousands of patients while helping anchor a new European industry in biomimetic implants and paving the way for future applications in vascular repair that strengthen Europe’s health sovereignty and global competitiveness.

Keywords: tissue engineered vascular grafts,regenerative cardiovascular implants,biomimetic implants,vascular tissue engineering,regenerative medicine platform,biomimetic tissue engineering platform
Investigating Somatic Multimorbidity in People with Mental Disorders Using Innovative Metrics and National Register-based Data (SOMULTIMATE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 247553.28
EU funding (EUR): 247553.28
Participants: 1
Project status: SIGNED

Despite the strong evidence on common occurrence of physical health conditions and their profound negative impact on survival in people with mental disorders, existing research has focused predominantly on the presence of single, distinct physical health conditions in these people. Somatic multimorbidity, denoting the coexistence of two or more chronic physical health conditions, remains incompletely described and understood in people with mental disorders. Furthermore, while it is known that the staggeringly lower life expectancy in people with mental disorders is explained by natural causes of death, the precise contributions of somatic multimorbidity to premature mortality have not been studied systematically. A major impediment in furthering knowledge is the prevailing methodology, consisting of solely counting of the number of physical health conditions, which is inherently unable to reveal the complex nature of somatic multimorbidity. The focus of SOMULTIMATE is to apply novel metrics on Danish national, register-based data that will allow to better capture the true burden of somatic multimorbidity in people with mental disorders. By considering the entire spectrum of mental disorders, SOMULTIMATE will provide the most comprehensive estimates (i) of the extent and patterns of somatic multimorbidity and (ii) of the impact of somatic multimorbidity on mortality in these conditions. This would facilitate the identification of the most common somatic multimorbidity, including in a wide array of so far overlooked mental disorders, and potentially inform screening targets for physical health conditions in various settings. Unravelling the precise contributions of somatic multimorbidity to premature mortality would then provide actionable targets to reduce the life expectancy gap. In addition, the methodological advances introduced by SOMULTIMATE would be directly applicable in diverse areas of medical research.

Keywords: epidemiology psychiatry physical health conditions mental physical health interface multimorbidity mortality life expectancy gap life years lost health metrics national registers
trAining younG researchers On shaping MetaveRse for business and social vAlue (AGORA) (AGORA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Cyprus,Germany,United Kingdom,France,Greece,Norway,Italy,Lithuania,Portugal
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2023-09-01
End date: 2027-08-31
Duration (months): 48.0
Total project cost (EUR): 4570732.8
EU funding (EUR): 3829874.4
Participants: 13
Project status: SIGNED

As metaverses operate in real-time their wide adoption is expected to create digital public spaces for interaction in which the already possible online interactions are intensified and blended with the physical world as never before. To lead in this field and maximize positive implications, Europe needs to ensure that new multi-dimensional challenges arising, are addressed in accordance with European values. AGORA responds to the lack of doctoral programs which go beyond the technical understanding of Metaverses and consider its business and social value while unpacking and addressing potential unintended consequences. Through a rigorous and robust research and training programme, AGORA aims to develop a critical research and talent base capable of leading by example. AGORA’s approach is to train the researchers not only to understand Metaverse's infrastructure but also to understand and oscillate between the different levels of Metaverse’s business and societal value, paving in this way a more integrated understanding of this disruptive ecosystem. Combining theoretical and hands-on industrial research and transferable skills training will enable researchers to target high-quality publication outlets and to become creative and autonomous so that they can exploit and commercialize research results and become competitive in the global arena. One of AGORA’s unique selling points is its ability to prepare the ESRs to work in any of the three pathways (academia, industry, policy making) as well as their intersections. AGORA's inter-sectoral network brings together leading academic and non-academic co-supervision arrangements of high quality, stimulates the development of new industrial doctoral training procedures between top business schools and industries in the region.

Keywords: metaverse,virtual worlds,web 4 0,business value,societal implications,ecosystems
Novel pharmacological treatment for cognitive function improvement in Alzheimer’s disease (COGNIFY)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 11.0
Total project cost (EUR): 2300000.0
EU funding (EUR): 2300000.0
Participants: 1
Project status: SIGNED

Alzheimer’s disease (AD) is the most well-known form of cognitive impairment. It is a progressive neurodegenerative condition characterized by an initial silent phase, followed by symptoms such as memory loss, impaired judgment, and mood changes. Accumulation of beta-amyloid and tau proteins in the brain leads to a loss of cholinergic neurons, ultimately affecting cognitive function. AD significantly impacts the physical, emotional, and economic well-being of the 30-40 M patients affected worldwide. Existing treatments fall short, failing to sustainably address cognitive impairments in AD, while safety concerns and poor tolerability limit therapeutic benefits, exacerbating the burden on patients and caregivers. Kynexis is developing KYN-5356, a first-in-class drug compound with high potential to become the first multimodal pharmacological solution capable of addressing multiple components of cognitive impairment in AD. Kynexis’ innovation is backed by comprehensive pre-clinical findings that not only confirm the unique mechanism of action but also suggest a high capacity to improve cognitive function in AD. The pre-clinical data also demonstrates a favorable safety profile with no adverse effects on the peripheral nervous system. The EIC project will support a phase 1/2a clinical study, allowing Kynexis to collect essential efficacy data in AD. COGNIFY is a high risk-high gain project, as it ambitiously targets the urgent, yet unmet need for effective AD treatments, despite the historically low success rates of clinical trials in this field. The project will help Kynexis accelerate the development of KYN-5356 as a precision treatment for AD, representing a new hope for patients and their families in the fight against this disease.

Keywords: alzheimer s disease,cognitive impairment,precision treatment,kynurenine pathway
Biointegrable soft actuators alimented by metabolic energy (INTEGRATE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands,Italy,Belgium,Switzerland,France
Call: EIC Pathfinder Open 2021 (HORIZON-EIC-2021-PATHFINDEROPEN-01, 2021)
Start date: 2022-06-01
End date: 2026-05-31
Duration (months): 48.0
Total project cost (EUR): 1698750.0
EU funding (EUR): 1698750.0
Participants: 5
Project status: SIGNED

State-of-the art implantable actuating devices, such as automated prosthetics, have time-limited operational capacities because they are sustained by batteries which, ultimately, rely on external power sources to be recharged. INTEGRATE proposes a radically new way to solve this problem: use metabolic energy from the patient to power implanted devices. To achieve this ambitious goal, INTEGRATE will develop i) new 3D printable soft actuating materials inspired by human muscles whit high performances and low power consumption and ii) an artificial organ capable of harvesting metabolic (biochemical) energy and transform it into electricity. The actuating materials (Bionic Muscles) will be prepared via self-assembly of biocompatible colloidal liquid crystals and stimuli-responsive polymers. A modular design and 3D printability will offer the possibility to manufacture these materials on the basis of patient’s anatomy and needs. The Energy-Harvesting Organ will be capable of converting pH differences within various body fluids (e.g. gastric juice and saliva) in electricity with high efficiency, providing the necessary power to sustain the Bionic Muscles. This research will revolutionize the field of implantable devices and will represent a turning point in robotics, wearable technologies, materials science, energy conversion, and materials engineering.

Keywords: artificial muscles,bionics,energy autonomous prosthetics