Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Disruptive imaging technology for accurate and painless breast cancer diagnosis (GI-BCT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-05-01
End date: 2018-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Breast cancer is the most prevalent form of cancer in women, as 1 in 9 women are affected and 1 in 30 will die from the disease. Early detection is essential to reduce the mortality, thus countries have established routing screening programs. The problem is that main screening procedure of mammography is painful for patients, produces high rate of false positives for women with dense breast tissue, provides limited contrast, low-resolution and poor tissue discrimination properties. False positives lead to performing unnecessary therapeutic procedures. Also cancer in dense breasts is missed out by mammography, lowering survival outcomes when discovered in later stage. GratXray is entering the 3,56 BEUR size breast imaging market with our disruptive grating interferometry-based breast computed tomography – GI-BCT technology. GI-BCT will provide painless, efficient and precise breast cancer imaging. The breast will be scanned in its natural state in 3D, without compression and contrast agents, yielding images with a much higher contrast and better resolution. Thus saving €1,85B in healthcare costs in Europe and US by avoiding recalls, €640 000 from machinery costs for breast centers and potentially save treatment costs in the amount of €95 000 per patient. We have worked for the past 15 years in GI-BCT research and have a solid patent portfolio of 8 granted patents. Currently, we have demonstrated our technology in operational environment, and we are ready to start first clinical trials in 2D with the goal to make first sales in Q1 2021. We have formed a team that combines strong scientific, industry and user know-how. We estimate that a further investment of €5M and 3 years is required to reach the commercialization stage. We estimate that in year 6 we have hired 50 employees, sold 59 systems per year, have 207 service contracts, revenue of 68 MEUR, net profits of 21 MEUR and reach ROI of 4 (400%).
Circular business models for the solar power industry (CIRCUSOL)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Enabling the transition towards a green economy and society through eco-innovation
Action type: Innovation actions
Countries involved: Germany,Germany,Spain,Switzerland,Sweden,Belgium,Belgium,Belgium,Belgium,Lithuania,Belgium,France,France,France
Call: Systemic, eco-innovative approaches for the circular economy: large-scale demonstration projects (H2020-CIRC-2017TwoStage, 2017)
Start date: 2018-06-01
End date: 2022-11-30
Duration (months): 54.0
Total project cost (EUR): 8248614.25
EU funding (EUR): 7014892.76
Participants: 18
Project status: SIGNED

Solar power generates nearly 4% (and still growing) of Europe’s electricity demand. In 2021, the 200 GW of capacity installed in Europe will result in saving of 219 million CO2 tons/year. By 2030, 8 mill tons of PV panels are expected. Resource efficiency is a critical success factor for the solar power sustainable growth. Performance-based, third-party ownership Product-Service System (PSS) has been widely seen as a key circular economic model to stimulate resource efficiency and reduce waste generation. CIRCUSOL aims to establish solar power as a spearhead sector to demonstrate a path driven by PSS business models towards a circular economy in Europe. Through a co-creative approach with end-users and the entire value chain, CIRCUSOL will develop two main blocks of a circular PSS model: circular product management with re-use/refurbish/remanufacture (“second-life”) paths in addition to recycling, and value-added new product-services for residential, commercial and utility end-users. Five large-scale, real-life demonstrators will be set up in these 3 market segments, in 3 European countries (FR, BE and CH) to validate market acceptance, business viability and resource efficiency benefits. CIRCUSOL will deliver tangible innovation for the solar power industry with market-validated PSS business models, 2nd-life PV/battery labelling/certification protocols and cost/application analysis, and an info-sharing ICT platform. The results will be exploited in FR, BE and CH and prepared for replication in Europe (Letters of Support of stakeholders attached). CIRCUSOL will also deliver verified circular business innovation methodologies for broader use by other industries, sustainability professionals and academia; plus evidence-based knowledge in circular economy implementation for policy makers. All together, CIRCUSOL will contribute to a more resource efficient Europe, while reducing GHG emissions and creating new business opportunities and jobs.

Keywords: circular economy,business model,large scale demonstrator,product service systems,resource efficiency,solar power,photovoltaic,battery,innovation methodology,second life products,co creation
PJ01 Wave 2 Enhanced Arrivals and Departures (PJ01-W2 EAD)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Austria,Germany,Germany,Germany,Spain,Ireland,Italy,Germany,Switzerland,Norway,Croatia,Sweden,Sweden,Belgium,France,France,France,France,France,Netherlands,Denmark,United Kingdom,United Kingdom
Call: PJ.01 W2 Enhanced Arrival and Departures (H2020-SESAR-2019-1, 2019)
Start date: 2019-11-01
End date: 2023-06-30
Duration (months): 44.0
Total project cost (EUR): 12685578.4
EU funding (EUR): 7806581.77
Participants: 28
Project status: SIGNED

In order to meet the forecast traffic growth, and in particular to address the performance issues encountered in summer 2018, PJ01-W2 will develop concepts, tools and procedures to increase the capacity of Terminal Manoeuvring Areas (TMAs) in a safe, cost-effective and environmentally sustainable manner. This will be achieved by taking advantage of the latest technological developments from both an airborne and a ground-system perspective and through the secure sharing of data. The needs of all Airspace Users will be addressed including Rotorcraft. The aim will be to improve the capacity whilst exploiting the environmental benefits achieved from Continuous Climb Operations (CCO), Continuous Descent Operations (CDO) and improved arrival sequencing. A focus will be to minimise delays and improve resilience and predictability for capacity-constrained high-density/complexity TMAs. This will be achieved by enhancing arrival and departure management by the dynamic use of precision navigation routes and optimised profiles. Traffic flows will be optimised by improving the integration of the management of departures with arrivals, including extended Arrival Manager (AMAN) and ground holding from in-horizon departures, and by improving the capability to balance traffic demand and available capacity across the network and airports. The use of procedures and technologies to improve integration of rotorcraft operations within TMAs, and interoperability with General Aviation (GA), drones and Remotely-Piloted Aircraft System (RPAS), will be addressed which will also provide increased resilience in poor weather. To ensure that the full benefits are achieved and that the expected performance improvements are realised in the context of the overall ATM network, close co-ordination will take place with other projects, particularly those addressing airport management, network management, trajectory and separation management and the overall content integration within the programme.

Keywords: arrivals,departures,queue management,rotorcraft,climb,descent,aman,dman,dynamic routes,extended aman,xman,systemised airspace,rpas
CLIMATE ASSESSMENT OF INNOVATIVE MITIGATION STRATEGIES TOWARDS OPERATIONAL IMPROVEMENTS IN AVIATION (ClimOP)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Germany,Italy,Türkiye,Netherlands,Netherlands
Call: Aviation operations impact on climate change (InCo flagship) (H2020-MG-2019-SingleStage-INEA, 2019)
Start date: 2020-01-01
End date: 2023-06-30
Duration (months): 42.0
Total project cost (EUR): 3064272.5
EU funding (EUR): 3064272.5
Participants: 8
Project status: SIGNED

Air Transport has for a long time been linked to environmental issues like pollution, noise and climate change. Aviation emissions, such as carbon dioxide (CO2), water vapour (H2O), nitrogen oxides (NOx), soot and sulphate aerosols, alter the concentration of atmospheric Greenhouse gases and trigger the formation of contrails and cirrus clouds. The share of aviation amongst all anthropogenic CO2 emissions is about 2% (ATAG). However, studies estimate the climate impact from aviation for the year 2005 including non-CO2 emissions to roughly 5% of the total anthropogenic radiative forcing (Lee et al., 2010). Considering the projected growth of air traffic for the next decades of 5% (RPK) per year, aviation’s share of the total anthropogenic climate impact is expected to increase further. Consequently, intergovernmental organizations, aircraft manufacturers and operators and the research community are increasingly focusing on different technological, operational and regulatory climate impact mitigation options. In this framework, ClimOP aims to identify, evaluate and support the implementation of mitigation strategies to initiate and foster operational improvements which reduce the climate impact of the aviation sector. Operational improvements correspond to any operational measure or action taken through time in order to improve the current provision of aviation operations. The overall objective of ClimOp is to define actions and advice for policymakers by proposing a set of most promising and harmonized mitigation strategies.

Keywords: mitigation strategies,operational improvements,climate impact,aviation sector
Gas-phase two-dimensional rovibrational infrared spectroscopy of volatile organic compounds (GASIR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Poland,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-05-01
End date: 2024-07-30
Duration (months): 30.0
Total project cost (EUR): 192762.24
EU funding (EUR): 192762.24
Participants: 2
Project status: SIGNED

The goal of the fellowship is to build an ultrasensitive two-dimensional infrared spectrometer and apply it to detection of complex mixtures of trace amounts of volatile organic compounds (VOCs). Third-order spectroscopies using ultrashort pulses, such as 2D IR spectroscopy, are powerful tools for studying both structure and dynamics. They probe the evolution of state-to-state coherences between quantum states and evolution of state populations on femtosecond to nanosecond timescales, in between excitation by ultrashort optical pulses. In terms of molecular properties, 2D IR spectroscopy probes correlations between molecular bonds, which strongly depend on the structure of the molecule as a whole. Compared to linear spectroscopy, which is more bond-specific, 2D IR spectroscopy provides much greater selectivity. Compared to mass spectrometry methods, it is applicable to both small inorganic molecules and to VOCs and easily lends itself to quantitative analysis. 2D IR spectroscopy has not been used for trace-gas analysis up to now because of insufficient sensitivity. This project overcomes this problem by building first of its kind cavity-enhanced 2D IR spectrometer, with up to four orders of magnitude better sensitivity than the previous state of the art, and applying it to vibrational spectroscopy of VOCs. The potential for exploitation of the project outcomes includes breath analysis diagnostics, detection of explosives, narcotics and other trace-gas analysis problems. There are also many potential applications of the outcomes in basic science, in the field of ultrafast dynamics of optically dilute samples (e.g. cold molecular jets or sub monolayer films). Two notable examples include the problem of intramolecular vibrational energy redistribution and the dynamics of hydrogen bond networks. The expertise and unique skills gained during the outgoing phase will be used to establish a new research program in the host institution.

Keywords: cavity enhanced spectroscopy,frequency comb,2d spectroscopy,ultrafast spectroscopy,trace gas detection,volatile organic compounds
Targeted contrast agents to better detect pancreatic tunor and its zinc content by MRI on mice (tZR-CA-InVivo)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-11-01
End date: 2025-11-29
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: SIGNED

Pancreatic cancer has the lowest survival rate Pancreatic cancer has the lowest survival rate of all cancers in Europe, the median survival time is only a few months due to the lack of test for early diagnosis, and no effective therapies for metastatic forms. Pancreatic Ductal Adenocarcinoma (PDAC), like prostate and hepatocellular cancers present a down regulation of zinc importers and low zinc content. Treatment with clioquinol, a zinc ionophore, to increase the amount of zinc in the tumor has shown to inhibit tumor growth. This project aims at creating new tool to better detect PDAC by Magnetic Resonance Imaging, and the evaluation of di zinc ionophore to elevate the content in zinc in the tumor environment. Using the same modular approach, a normal and a zinc responsive contrast agent targeted to the PDAC will be synthesized by conjugation of a peptidic sequence known to target the tumor bearing a Single Core Multimodal Imaging Platform for quantification, with a peptide functionalized with a normal or zinc responsive contrast agent. After careful characterizations in vitro and ex vivo, they will be used in mice implanted with orthoptic pancreatic tumors. One of the projects developed by the “Metallic complexes for MRI” group, consist designing and using MRI probe for various substrates, including zinc. The group masters all the techniques to characterize the contrast agents, and the experience researcher (ER) will bring the knowledge about zinc biology, and infrared microscopy to quantify the contrast agent in tissues. Benefiting from the competitive interdisciplinary environment of CBM, and within the group, the ER will acquire new technical skills, knowledge and network the frontier between chemistry, biology and MRI imaging, in particular working with animal model (mice), to adequately implement the project and complete her skill set to become an independent researcher interested in developing tools to study the role of metals in biological context.

Keywords: mri zinc responsive probe,peptide,pdac
European electro-optic and nonlinear PIC platform based on lithium niobate (ELENA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Partnership: Photonics (cPPP)
Countries involved: Germany,Germany,Germany,Switzerland,Switzerland,France,France,France,France,France
Call: Advancing photonics technologies and application driven photonics components and the innovation ecosystem (H2020-ICT-2020-2, 2020)
Start date: 2022-01-01
End date: 2025-06-30
Duration (months): 42.0
Total project cost (EUR): 4982900.72
EU funding (EUR): 4982900.63
Participants: 12
Project status: SIGNED

ELENA will develop the first European lithium niobate on insulator (LNOI) PIC platform, accessible to all interested entities in the form of an open foundry service. Lithium niobate (LiN) is one of the most promising emerging materials for PICs that comprises a unique set of interesting optical properties: a high electo-optic (EO) coefficient, a high intrinsic second-order nonlinearity, and a large transparency window. The focus of ELENA will be on developing 5 advanced photonic building blocks (BBs) which exploit the unique properties of LiN to enable novel functionalities in PIC (e.g. wavelength conversion and parametric gain) and to improve the existing ones (e.g. faster, more energy-efficient EO modulators). These BBs will be a part of comprehensive PDK library that will be accessible to entities outside of the consortium. ELENA’s approach will enable reliable monolithic integration of the LiN BBs to implement complex functionalities with better sensitivity, higher energy efficiency, faster speed and increased chip density. ELENA’s technologies will be applicable to a broad range of applications from telecom to LIDAR, quantum technologies and space. Moreover, ELENA’s ambition is to establish the key steps of a fully European supply chain to support the LiN platform. This include activities such as • Establish a process to produce 150mm optical grade LNOI wafers on an industrial scale • Develop a reliable and flexible packaging solution to interface LiN chips with optical fibers and other PIC platforms • Demonstrate the technology and validate the results by developing 4 PIC prototypes designed by 3 “end-user” partners covering fields of telecom, quantum technologies and microwave photonics The ELENA project (42 months, €5M) with a consortium of 3 RTDs , 3 large industrials and 3 SMEs contains all the necessary competencies to reduce the R&D costs of advanced PICs and implement the key aspects of a value chain for a sustainable LiN based PIC industry in Europe

Keywords: lithium niobate,linbo3,lnoi,pic platform,foundry,electro optic modulator,wavelength conversion,tunable cavity,monolithic integration,telecom,quantum,sensing,microwave photonics
Bootstrap and Uniqueness for Form Factors and the S-matrix (BUFFS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

Scattering amplitudes and form factors are fundamentally important quantities in quantum field theories, directly related to physical observables such as probabilities of particle interactions measured in collider experiments. Over the last decades, studies of these objects have revealed beautiful physical and mathematical structures, which have inspired powerful computational methods making accessible previously impossible calculations. The goal of this project is to further uncover such hidden structures, by exploiting a surprising interplay of fundamental principles. One focus will be on recently discovered infrared and ultraviolet principles, their possible duality, and how they can be used to construct scattering amplitudes in new ways that expose unitarity as an emergent property. Next, the project will explore the expression of unitarity as a geometry of positive constraints, which was conjectured to fully define string theory amplitudes. The final main goal is the application of such on-shell principles and the color-kinematic duality to form factors, off-shell generalisations of scattering amplitudes of great phenomenological importance. The project also encompasses a comprehensive program for the dissemination and communication of its results. The former will be based on publications in high impact journals and talks at major conferences, while the latter involves diverse outreach activities targeted at a wide range of audiences. The researcher will benefit from a bespoke training program, including courses in career management, public engagement, teaching activities, and participation in scientific workshops. The balanced distribution of these complementary activities is designed to optimise the benefit for the researcher, to increase his visibility and independence, to enhance his skills portfolio and, hence, to prepare him for a permanent academic position in the future.
Advanced Plug-in Hybrid Electric Drive System for Commercial Fleet Trucks (iPHEV)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Lithuania
Call: Small business innovation research for Transport (H2020-SMEINST-1-2015, 2015)
Start date: 2015-09-01
End date: 2016-02-29
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Economic, environmental and energy security factors provide a rational basis for switching to more efficient and less polluting vehicle technologies. Another even more important reason for the development of such technologies is the need to improve the air quality in the cities. Fleet users keep looking for cost-cutting solutions in order to remain competitive; they need to adapt to their customers' requirements for more sustainable transport solutions and to prepare for the future market demand and regulations. We have a multiple value proposal for commercial fleet managers – a cutting-edge iPHEV system that can be installed in new LCVs to save fuel costs per work cycle, reduce emissions and noise, improve capacity, and cut operation and maintenance costs. The system can be installed in different OEMs models with a retarder. iPHEV can be used in 3.5t LCV: utility work trucks, delivery vans, and minibuses. Furthermore, we are planning to develop and implement the system in MCV. The iPHEV proved to be an efficient part of the vehicle and the tests confirmed the compliance to the specification of the overall system and proper operation under real on-road conditions. The performance indicators show the viability of the prototypes in Iveco Daily models. Development of high-impact Plug-in Hybrid technologies that may lead to the reduction of greenhouse gas emissions and fuel efficiency is an urgent need in many global areas, including Europe. iPHEV demonstrations have already received a lot of attention from potential customers and government representatives in Norway, Sweden, Denmark. For the purpose of the iPHEV project justification, we are going to prepare a technical/practical and economic feasibility study, including business plan. Subject to positive recommendations of the feasibility study, we are going to submit a proposal under H2020 SME Instrument Phase 2.

Keywords: phev,alternative fuel,emissions,energy consumption