Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
CRESCINE – INCREASING THE INTERNATIONAL COMPETITIVENESS OF THE FILM INDUSTRY IN SMALL EUROPEAN MARKETS (CresCine)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Portugal,Estonia,Croatia,Belgium,Lithuania,Netherlands,Germany,Denmark,Ireland,United Kingdom,France
Call: Increase the potential of the international competitiveness of the European filmmaking industry (HORIZON-CL2-2022-HERITAGE-01, 2022)
Start date: 2023-03-01
End date: 2026-02-28
Duration (months): 36.0
Total project cost (EUR): 3997683.75
EU funding (EUR): 3997683.5
Participants: 29
Project status: SIGNED

CRESCINE’s mission is to increase the competitiveness of the film industry across small countries in Europe and improve the circulation of films and AV content coming from small markets internationally. CRESCINE’s aims to enhance the competitiveness and the cultural diversity of the European film industry. This will be achieved by understanding, engaging with, empowering, and ultimately transform European small markets setting out from research and piloting in 7 markets. In their “smallness", these markets underline the challenges and drivers one must consider to increase the competitiveness of the EU film industry as all. CRESCINE will address, systematically, the whole film production, distribution and consumption ecosystem. The aim is to innovate at all levels of the value chain, from policies to ways of data management and analytics, production business models and modes of distribution. CRESCINE will develop novel tools, methods, and strategic approaches that all build on the concept of smallness and the positive affordances it entails for the overall competitiveness of the European film industry. CRESCINE will address all expected outcomes of the call through the lens of exemplary European Small Film Markets which stand for the majority of film markets in the European Union. CRESCINE will establish an innovative model of analysis and evidence collection across the value chain that is framed by cutting edge data analytical models, comparative benchmarks promulgated in light of best available evidence including unprecedented data sources. The findings will lead to work on innovative solutions and testing of new tools, policies, business models or financing schemes, and green strategies. These activities feed the overall impact of the project and its ability to produce new tools, recommendations, guidelines, and exploit results that nurture the transformation of the film industry in small European markets and beyond.

Keywords: film and av small european film markets digital shift business innovation digital production digital ecosystems audiences
Knocking on the Vatican's Gates. Refugees, the Holy See, and the Spectre of Communism, 1945-1958 (COMREF-VATICAN)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 183600.96
EU funding (EUR): 183600.96
Participants: 1
Project status: CLOSED

This project will be the first to explore the crucial – but hitherto neglected – role of the Vatican Relief Commission (the Pontificia Commissione di Assistenza, PCA) in assisting and resettling European refugees after World War II and in the early Cold War. It takes advantage of an unprecedented opportunity: the opening of the part of the Vatican Apostolic Archive (or VAA, named the Vatican Secret Archive until 2019) pertaining to the pontificate of Pius XII (1939-1958) in March 2020. To meet its central aim - providing a new understanding of Western humanitarianism in the postwar period - this project interrogates the documents held in VAA to integrate the missing puzzle piece of papal aid into the picture of the international refugee assistance. It demonstrates the importance of the Vatican’s faith-based humanitarianism and its use of refugees from Eastern Europe as a playing card in building an anti-communist defensive. Three objectives are to be achieved in the lifetime of the project: A) to conduct intensive archival research in the untapped collections of VAA and to triangulate this with material from the archives of the International Refugee Organization (IRO) and United Nations High Commissioner for Refugees (UNHCR) B) to analyze this primary source material in order to revisit historiographical assumptions on the post-war refugee regime, international humanitarianism, the Catholic Church, and the Cold War C) to disseminate the research findings to the scholarly community, the public, refugees, and policymakers, drawing attention to the importance of historicizing refugee experiences and policies. The methodology of this project combines historical analysis of original archival sources, qualitative research techniques, and interdisciplinary conceptual frameworks. Integrating institutional and bottom-up perspectives, it highlights the issues of gender, class, and ethnicity in experiencing and negotiating displacement.

Keywords: cold war,refugee history,soviet union,vatican,archives
Chaotropic delivery of fully anionic oligonucleotides (BOOST)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-08-01
End date: 2028-07-31
Duration (months): 24.0
Total project cost (EUR): 194074.56
EU funding (EUR): 194074.56
Participants: 1
Project status: SIGNED

Developing effective membrane transporters is a key challenge for the delivery of nucleic acid-based drugs. Despite the exponential discovery of such biomolecules with therapeutic potential, the majority of them may need to be discarded from further development for being too hydrophilic to cross the lipid membrane. Future delivery technologies require the development of conceptually new approaches that can overcome the emerging limitations of current carriers and strategies. Recently, superchaotropic boron clusters have been validated to activate the transport of a broad range of hydrophilic cargos. The “anionic nature” of these clusters offers an alternative transport scenario. The clusters will not aggregate with hydrophilic anionic domains and, instead, will be repelled by anions. Therefore, they could be exploited to modify the structure of cargos without altering their solubility and function. The main goal of this action is the connection of superchaotropic boron clusters to hydrophilic biomolecules such as probes and nucleic acids to enable their autonomous membrane transport, while preventing self-aggregation and unspecific interactions with other biological surfaces. This will be achieved through an interdisciplinary approach that will simultaneously provide me with valuable training in chemistry, biology and biophysics, promoting my scientific independence. Short oligonucleotides will be designed to incorporate a variable number of modified nucleosides for future functionalization with boron clusters. Modified oligonucleotides, such as those bearing alkyne or azide functions, will be purchased from commercial sources and combined with cluster derivatives using click chemistry. These new chaotropic oligonucleotide hybrids will allow understanding and validating the application of self-delivering fully anionic nucleic acids with therapeutic potential.

Keywords: supramolecular chemistry superchaotropic carriers boron clusters membrane transport nucleic acid chemistry
Tuning of PHOtonic resonators (TUPHO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2023-12-01
End date: 2025-05-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Silicon photonics has progressed enormously over the last 15 years: large microelectronics manufacturers and small companies are now working on the subject, with identified products. The reproducibility of micro and nanophotonic devices remains a central technological barrier, to be broken. The dimension errors of cleanroom devices are 1 to 10 nanometers (1%), limiting applications. We have discovered a technique that makes it possible to absorb these errors at the end of manufacturing, permanently. We can tune photonic resonators with an accuracy of 10^(-4), and make them strictly identical when necessary. In this POC project, the patented technique will be transposed on silicon devices of interest, in a simple configuration for manufacturers.
Pharmaco-modulation of epithelia for induction of antimicrobial peptide expression: a disruptive approach to fight antibiotic resistance (MaxImmun)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: France,Germany,Sweden
Call: EIC Pathfinder Open (HORIZON-EIC-2023-PATHFINDEROPEN-01, 2023)
Start date: 2024-01-01
End date: 2027-12-31
Duration (months): 48.0
Total project cost (EUR): 3194450.0
EU funding (EUR): 3194450.0
Participants: 7
Project status: SIGNED

The MaxImmun project aims at preventing and treating infections, and situations of conflict between the host and its microbiota, by developing a disruptive technology based on molecules that boost antimicrobial peptides (AMP) of the innate immune system. To face the problem of antibiotic resistance, this high-potential technology may be relevant both in situations of endemic infections in the developing world, and infectious or inflammatory pathologies in industrialized countries. Our objective is to establish the proof-of-concept that among a series of hit molecules identified for their capacity to promote AMPs, a small subgroup may qualify to lead molecules that can then be pushed into the late phases of the R&D pipeline, with the perspective of a phase I clinical trial. To achieve this transition, our project will range from the comprehension of microbial mechanisms leading to antibiotic resistance, to the comprehension of AMP regulations, the identification of molecules and their optimization by medicinal chemistry, and the characterization and evaluation of their protective efficacy in pre-clinical validation models. Thus, we expect to develop innovative molecules as future antimicrobial drug candidates.

Keywords: therapeutic innovation,antimicrobial resistance,antimicrobial peptides,innate immunity,one health,molecule screening,medicinal chemistry,pre clinical models
INNOVATIVE APPROACHES FOR MARINE AND FRESHWATER BASED INGREDIENTS TO DEVELOP SUSTAINABLE FOODS AND VALUE CHAINS (IMPRESS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Innovation actions
Countries involved: Ireland,Serbia,Poland,Spain,Greece,Israel,Norway
Call: Innovative food from marine and freshwater ecosystems (HORIZON-CL6-2022-FARM2FORK-02-two-stage, 2022)
Start date: 2023-05-01
End date: 2027-04-30
Duration (months): 48.0
Total project cost (EUR): 6725261.25
EU funding (EUR): 5995286.51
Participants: 14
Project status: SIGNED

The overall vision of IMPRESS is to develop series of innovative actions to address key sustainability challenges associated with marine and freshwater sector from sea to shelf. These challenges include (i) valorisation of processing waste streams & (ii) utilisation and promotion of underutilised low trophic species (LTS). IMPRESS will tackle these broad challenges by meeting the following six specific objectives that collectively deliver co-benefits for environment, health, society and the blue economy. IMPRESS will promote and influence consumer perceptions towards LTS by highlighting their positive nutrition, health, environmental footprints and enhance professional skills and competences. IMPRESS will develop innovative approaches to valorise side streams and processing waste for creation of eco-friendly zero waste value chains; develop and deliver diverse range of products to address nutrition, health, wellness and consumer choices; enabling and evaluating innovative processing approaches, including beyond state-of-the-art technologies across the value chain, creating novel value for food, feed, ingredients, biopolymers and bioactives production. Finally, co-design novel, circular value propositions to accelerate the operationalisation of transition pathways ahead of future challenges, e.g. Farm to Fork 2030 goals; empower stakeholders to transition from current practices to a more innovative production and processing of LTS, using dynamic tools/demonstrations and multi-actor knowledge exchange. The key innovative actions of IMPRESS includes (i) promotion and introduction of new LTS from fresh and marine waters; (ii) develop robust valorisation routes for side streams and waste; (iii) employ energy-efficient processing and fractionation techniques; (iv) deliver new products, value chains and services. Finally IMPRESS will demonstrate circular and sustainably interlinked value chains to maximize the value creation with a zero-waste approach.

Keywords: food processing,product development
Supplementum CrEticum: New Inscriptions from Crete. (SCENIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Switzerland,Greece
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-06-01
End date: 2027-05-31
Duration (months): 36.0
Total project cost (EUR): 297164.16
EU funding (EUR): 297164.16
Participants: 4
Project status: SIGNED

New investigations of the inscriptions from Crete are highly desirable and expected by historians and epigraphists of ancient Greece. The Inscriptiones Creticae (I.Cret.), vol. I-IV, published by M. Guarducci between 1935 and 1950, lacks both of the fifth volume, which should have been devoted to the inscriptions of Cretan localities that are no longer identifiable, and of a supplement on inscriptions discovered in the last 90 years. Many of the 15 geographical corpora included in the Inscriptiones Graecae (IG: the most important project on Greek epigraphy), such as those from Attica or Boeotia, received an update after many decades. Because I.Cret. was independently published, Crete was not a priority for IG, and an update dedicated to the Cretan inscriptions never appeared. Therefore, a new edition of all inscriptions from Crete is strongly needed, but it is beyond the possibilities of a single scholar, requiring a very long time. Excluding the re-edition of those inscriptions already collected in I.Cret., the proposed project is consistent with the time scale of a MSCA and would be beneficial to several disciplines. Specifically, it aims at providing: i) a corpus of the Cretan inscriptions not included in I.Cret. A broad scientific impact can be expected, as this corpus will be in synergy with I.Cret. and with findings from other fields (e.g. prosopography). ii) an open access digital database to make the result easily accessible. This digital database will help in improving the most popular open access epigraphic publishing projects for Greek inscriptions. The open-access database of epigraphic material will also be made palatable to a broader public, accompanying the collected inscriptions with photos, English translations, commentary, etc. Following the epigraphic tradition, a book edition in Latin will be printed, addressed to a specialised audience. Gender, social and environmental aspects, although not central to the project, are taken into account.

Keywords: greek epigraphy,greek history,crete,archaeology,classical reception
Palaeoecological Exploration of Human-Linked Biological Invasions on Madagascar (PALAEOINVA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-07-01
End date: 2025-06-30
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: CLOSED

Loss of biodiversity is one of the most urgent ecosystem threats, and this is particularly clear on tropical islands such as Madagascar. Effective conservation efforts should be informed by assessments of synergistic threats from deforestation, biological invasions, and climate change, which operate on multiple timescales. This proposal uses multidisciplinary biochemical analysis of bones from archaeological and paleoecological deposits on Madagascar to identify endemic predators (fosa) and small mammals (mouse lemurs and rodents) that may be vulnerable to deforestation and negative interactions with exotic counterparts (dogs, rats, and mice). Specifically, we will apply bulk stable isotope analysis to exotic and endemic animal bone collagen from the past ~3,000 years to characterize dietary niches and evaluate the potential for different cases of predation and competition. To obtain a deeper understanding of resource use than is possible with prevailing bulk isotope methods, this project will also include the stable isotope analysis of individual amino acids present in bone collagen. Radiocarbon data from the same bones will substantially contribute to our knowledge of past animal translocations in the western Indian Ocean region. We will also start to identify taxon-specific responses to past changes in resource availability by comparing stable isotope datasets from directly 14C-dated bones with regional records of past climate and vegetation change. These project components will pin-point the degree to which competition has exacerbated (or not) the vulnerability of endemic species to human land management and climate change. The research is consistent with both the current research foci of the host institution and the career interests of the applicant, and the results will answer questions important to the historical sciences, modern biodiversity conservation, and rural communities around the study sites.

Keywords: radiocarbon,stable isotope,amino acid,predation,deforestation,aridification
Metabolomics in food and nutrition (Foodomics)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Coordination and support actions
Panel: Environment and Geosciences
Countries involved: Slovenia
Call: ERA Chairs (HORIZON-WIDERA-2023-TALENTS-01, 2023)
Start date: 2025-02-01
End date: 2030-01-31
Duration (months): 60.0
Total project cost (EUR): 2497500.0
EU funding (EUR): 2497500.0
Participants: 1
Project status: SIGNED

The vision of the ERA Chair FOODOMICS is to create a research centre at the University of Ljubljana (UL) in the field of Metabolomics in Food and Nutrition. The project is set within the framework of the ERA Chair action to simultaneously realise the research potential of UL and to create a cutting-edge dynamic and sustainable research environment. With the support of a network of existing international/regional/national partners, SMEs, and stakeholders, research results will be fruitfully exploited whilst creating a springboard for UL to move from partial, small, and fragmented research to bigger innovation driven projects that can offer solutions for the needs of society. FOODOMICS is designed to mediate progress in science through development of new analytical methods and provision of measurement services applicable to plants, animals and humans. The activities will include both profiling (analyses of all measurable analytes to identify differences) and targeted analyses (quantification of chosen set of analytes). FOODOMICS comprises four work packages (WP) necessary for the required capacity building, with each addressing specific element needed to create a world-class metabolomics food and nutrition Centre of Excellence at UL. WP1 and WP2 are dedicated to three important issues: (i) management and coordination; (ii) constitution; and (iii) sustainability issues. WP3 is dedicated to fostering research and education. WP4 focusses on the transfer of knowledge and technologies. WP5 and WP6 will undertake comprehensive dissemination, communication and exploitation activities. An important outcome of this Project is that disparities in research and innovation performance between Slovenia and innovation leaders in EU will be significantly decreased. Far-reaching effects of FOODOMICS will be the creation of a world-class working environment and centre of excellence, as well as innovative start-up companies, all of which will strength the Slovenian and European economy.

Keywords: metabolomics,food and nutrition,bioinformatics,innovation,technology transfer,education,