Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Methods for Stroke Monitoring and Diagnosing based on BCG (MESMODI-BCG)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-11-01
End date: 2026-10-31
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 2
Project status: SIGNED

Clinical monitoring of the heart health of stroke patients is usually done by electrocardiogram (ECG) recording, a non-invasive method that requires electrodes in contact with the patient's skin to obtain the signal. However, since specialists are required to place the electrodes, its use is restrictive. Contactless alternatives for study of heart conditions in less restrictive way have been investigated for decades. This project aims to develop novel, non-invasive methods for detecting cardiac and non-cardiac disease in stroke patients using the ballistocardiogram (BCG) signal, allowing for patient monitoring without transfer to clinical settings. The objective of the project is to answer important questions in current research in biomedical engineering, such as whether the resolution of a BCG is sufficient for the detection of cardiac conditions and whether it can become the preferred method for monitoring heart health from home. To achieve this objective, the project proposes the development of a portable prototype for the acquisition of BCG signals, as well as the development of novel algorithms that allow for the detection and classification of cardiac arrhythmias and episodes of sleep apnea from these signals. The project will be based on three different stages: design and implementation of the prototype, obtaining new diagnostic support algorithms based on ballistocardiogram signals, and the connection strategy at the prototype to deliver the information to the specialist doctors. This is a multidisciplinary project that combines expertise in bioengineering, health sciences, electronics, and telecommunications. This proposal also aims to transfer knowledge to the host institution and provide training for the candidate in advanced techniques. The results have the potential to significantly improve the capacity of home health monitoring and the application of eHealth knowledge. This project is aligned with the EU strategy for the protection of human health.

Keywords: biomedical engineering,ehealth,stroke monitoring
A Game-Changing Solar-Thermochemical Heat Storage and Intensification Technology for the Process Heat Sector (SOLTEC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark,Netherlands
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 230774.4
EU funding (EUR): 230774.4
Participants: 2
Project status: SIGNED

This project proposes a game-changing integrated technology of solar collectors and Thermochemical Energy Storage (TCES) systems. This solution is primarily proposed to bring sustainability to the process heating sector, which has been so far very challenging to decarbonize due to a lack of cost-effective and reliable solutions. Besides this main feature, the proposed technology has some distinguishing attributes that make it groundbreaking scientifically and very competitive technically. These are 1) solving the technical challenges of TCES systems, namely material agglomeration over time and non-uniform heat distribution throughout the material within the reactor, 2) integration of the solar collectors' field and the TCES system leading to lowered capital and maintenance costs and increased overall efficiency, and 3) significant temperature lifting of the stored solar heat during the hydration phase of the thermochemical material enabling the system for process heating at much higher temperatures which are otherwise not possible by a solar energy system. With main hypothesis that the uniform flow of reactive material can effectively be controlled and helpful for its agglomeration and non-uniform heat distribution prevention, SOLTEC aims at laying the first stone of research on this technology and pushing the edges of the state-of-the-art through a) developing the theoretical principles of solar heat capturing/storing/intensification process, b) developing the optimal and compatible design of the collectors for this, and c) techno-economic and environmental evaluation of the technology. The project will develop the fundamental theories and methods to design, optimize, and test this innovatively operating solar system.

Keywords: thermochemical energy storage solar energy fresnel lens collector heat storage and intensification process heating
Delegating decisions: An overlooked way of pursuing immoral goals (DELEGATION)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-10-01
End date: 2030-09-30
Duration (months): 60.0
Total project cost (EUR): 1498269.0
EU funding (EUR): 1498269.0
Participants: 2
Project status: SIGNED

Modern societies are tormented by warfare, crime, corruption, and environmental exploitation. If many people have prosocial goals and desire to see themselves and to be seen by others as moral, how do immoral acts like these continue to happen? Economic research suggests a critical role of delegation: Decision-makers can delegate unethical, yet profitable decisions to delegates, which increases resource inequality, and at the same time averts punishment of delegators. Yet, such indirect immorality, as an inherently elusive, inconspicuous phenomenon, is not only overlooked by observers, but also by psychological research. Who delegates immoral behaviors, when, and why? What determines observers’ reactions to delegators? I propose the new 3R framework of delegation and test it in three empirical work packages spanning diverse methodology from social, moral and cognitive psychology and behavioral economics: People employ delegation strategically to reap the benefits of immoral acts while effectively avoiding responsibility and protecting their moral reputation in the eyes of others. Basic social-cognitive mechanisms explain these intra- and interpersonal benefits of delegation. Whereas previous work often focused on the few callous individuals who do not care about moral norms, the 3R framework assumes that precisely those who are morally motivated delegate immoral decisions to minimize their guilt and escape social blame. Moreover, I predict and test an important asymmetry in how observers assign blame and praise for delegated immoral versus moral behaviors. Given the fundamental psychological nature of immoral delegation, it should be frequent in people’s everyday lives and should already be observable in children. Taken together, the project aims to comprehensively study delegation under a unifying framework. It will contribute a groundbreaking new perspective to the study of immoral behavior, and thereby illuminate the complex social nature of human morality.

Keywords: moral judgment,immoral behavior,moral blame,moral praise,hypocrisy,self serving morality,prosociality
LEAVE NO ONE BEHIND: BOTTOM-UP ENERGY TRANSFORMATION OF LAST-MILE COMMUNITIES (SWARM-E)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Innovation actions
Countries involved: Germany,Bangladesh,Rwanda,Tanzania, United Republic of,Kenya,Austria,Belgium,Spain,Bulgaria,Ireland,Italy
Call: Accelerating the green transition and energy access in Africa (HORIZON-CL5-2023-D3-02, 2023)
Start date: 2024-05-01
End date: 2028-04-30
Duration (months): 48.0
Total project cost (EUR): 5378338.75
EU funding (EUR): 4437613.75
Participants: 16
Project status: SIGNED

SWARM-E is a trans- and multi-disciplinary approach for sustainable, affordable and modern energy access and well-being for Sub-Saharan Africa, aligned with the AU-EU Agenda 2063. SWARM-E consists of several layers: 1) an innovative renewable electricity infrastructure, the SWARM grid, a circular and cyber-smart network where end-users exchange electricity of their solar home systems and form the nodes of a smart grid which can dynamically grow to meet demand; 2) unlocking unutilised renewable energy for productive uses in the water energy food nexus – cold storage, water purification, water pumping and irrigation, carpentry; 3) transfer and decentralisation of Global North energy transformation innovations – decentralised hydrogen production for cleaner cooking, bi-directional charging of light electric vehicles (two- and three-wheelers) to transport goods and people. SWARM-E builds on network effects generated through the inclusion of localised economies with strong producer-consumer linkages embedded within larger systems of trade and exchange for the creation of bottom-up energy communities. SWARM-E will operate and replicate 5 pilots in Rwanda and Tanzania, under which 5 SWARM grids are installed, delivering 6.9 GWh of renewable electricity while generating income through the trading of electricity and avoiding the discard of 3,200 batteries; 5 water purification applications deliver 101.M L of clean water; 15 light electric vehicles deliver farmers’ produce, power mobile productive uses and cold storage, increasing the yields of 1,000 farmers and reducing the food losses of more than 5,000; 700 kg of H2 are blended with LPG for cleaner cooking, and more than 500 jobs for women and youth are created. The balanced participation of EU and AU private, public and civil society organisations in the consortium will ensure the knowledge transfer North-South and South-South, and the sustainability of value chains based on local value creation and entrepreneurship.

Keywords: swarm electrification,bottom up energy communities,energy network,solar power,productive uses of energy,hydrogen production,
Advanced versatile artificiaAdvanced versatile artificial intelligence technologies and interconnected cross-sectoral fully-operational national focal points for combating illicit firearms trafficking (Ceasefire)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Fighting Crime and Terrorism
Action type: Innovation actions
Countries involved: Greece,Italy,France,Luxembourg,Netherlands,Cyprus,Ireland,Poland,North Macedonia,Moldova, Republic of,Serbia,Portugal,Slovenia,Spain
Call: Fight against firearms trafficking (HORIZON-CL3-2021-FCT-01, 2021)
Start date: 2022-10-01
End date: 2025-09-30
Duration (months): 36.0
Total project cost (EUR): 5862598.04
EU funding (EUR): 4999808.75
Participants: 26
Project status: SIGNED

Ceasefire targets the development of a highly innovative, holistic, multi-disciplinary, high-tech and versatile approach for significantly increasing/broadening the operational capabilities of EU Law Enforcement Agencies (LEAs) in their struggle to detect, analyze and track cross-border illicit firearms trafficking related activities. In particular, Ceasefire efforts will concentrate on the following major driving axes: a) The development of advanced Artificial Intelligence (ΑΙ) technologies for significantly facilitating the everyday work of the involved practitioners, and b) The establishment of fully-operational National Focal Points (NFPs), by targeting to alleviate from current organizational, operational, cooperation, legal, cross-jurisdictional, trans-border and information exchange challenges. The former corresponds to a wide set of AI-enabled tools, including solutions for cyber patrolling, Web data gathering, on-the-spot detection of firearms, advanced Big Data analytics, cryptocurrency analysis, large-scale information fusion, visual analytics and firearms-related intelligence collection. On the other hand, particular attention will be given towards defining models, protocols and procedures for making NFPs fully functional, complemented by activities for mapping the various legal frameworks (within different countries) and procedures (within different agencies) for harmonizing investigations, cooperation, lawful evidence collection and forensics analysis. The development of efficient information sharing mechanisms among LEA (police, border guard, customs), judicial and forensics authorities will further reinforce the system capabilities. Moreover, the tasks of Ceasefire will complement the objectives and activities of the EU Policy Cycle (EMPACT) – Firearms (where partner MIRPN acts as Driver and partner FMI as Co-driver), while continuous guidance from the European Firearms Experts (EFE) group (where partner PSP acts as the Chair) is foreseen.

Keywords: artificial intelligence,national focal points,incident tracking tool,seizure registration,dark web marketplaces,scanning technologies,3d printed firearm blueprints,cryptocurrencies
Advancing stroke care with cutting-edge ultrasound biomarkers for Neurocritical Care (RS-NeuroMarkers)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: France
Call: Transition Open 2024 (HORIZON-EIC-2024-TRANSITION-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 3562052.29
EU funding (EUR): 2493436.6
Participants: 1
Project status: SIGNED

Today, the lack of effective imaging kills. Early diagnosis can cure most deadly diseases, and stroke is a prime example. With one in four adults likely to experience a stroke, timely detection is crucial. Unfortunately, current imaging tools fall short for bedside diagnosis, wasting valuable time both in ambulances and at the patient’s bedside. To implement widespread screening and advanced therapies, to provide a diagnosis at the right time and thus save lives, we would need to increase the accessibility of CT scans and MRIs by 100-fold and drastically improve their limitations. The solution lies in enhancing ultrasound, a portable and accessible imaging modality. At Resolve Stroke, we are unlocking ultrasound's full potential with SYLVER, our innovative point-of-care ultrasound system powered by Software-Based Ultrasound technologies. SYLVER harnesses 100% of raw ultrasound data to deliver life-saving insights through advanced 3D algorithms and imaging. By combining ultrasound with advanced post-processing algorithms, SYLVER expands the boundaries of what ultrasound can achieve. Key opinion leaders are already identifying new critical applications for our technologies, extending beyond neurology into fields like oncology, to monitor tumor aggressiveness, and transplant vascularization. With access to this new ultrasound data, novel ultrasound-based biomarkers, such as RS-LVO (Large Vessel Occlusion detection) and RS-USP (Ultrasound Perfusion Score), have the potential to revolutionize stroke management and brain care. These biomarkers offer critical, quantitative insights comparable to those obtained through CT scans, but with the added benefits of the ultrasound modality. EIC support will enable us to develop, validate, and integrate RS-LVO and RS-USP into the SYLVER system, with validation in both laboratory and clinical settings to confirm their efficacy in real-world applications, at patient’s bedside.

Keywords: software based ultrasound,neurocritical care,stroke management,point of care imaging,bedside brain imaging,neuro biomarker,large vessel occlusion,brain perfusion
Intestinal Gluconeogenesis: Emerging Regulator of Energy Homeostasis (IGN)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: France
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-10-01
End date: 2028-09-30
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 2
Project status: SIGNED

Obesity and type 2 diabetes continuously progress worldwide, compromising healthy aging. Deregulated endogenous glucose production (EGP) is involved in hyperglycemia and its complications. Among the 3 organs (liver, kidney, intestine) contributing to EGP, I uncovered with my team that intestinal gluconeogenesis (IGN) has the capacity to interfere in the control of energy homeostasis. Indeed, intestinal glucose initiates a gut-brain circuit controlling both body weight and glucose production by the liver, the strongest quantitative contributor to EGP. Intestinal gluconeogenesis is, thus, a novel target to control obesity and diabetes. The IGN project has 3 objectives: Understand: is dedicated to elucidating the neural mechanisms by which IGN is sensed and send its signals to the brain. Our data suggested that glucose receptor sodium-glucose co-transporter 3 (SGLT3) could be the peripheral sensor of IGN. Moreover, we showed that the neuromediator calcitonin gene-related peptide alpha (CGRPa) is mandatory for the IGN signal. I will use original mouse models to map the SGLT3-neuron connection to the brain and define the role of CGRPa. Explore: aims at expanding the scope of IGN to the networking of hypothalamus during the neonatal period. I will assess whether the surge of IGN occurring during the neonatal period may control the development of neuronal connections between the hypothalamic nuclei, to ensure an optimal control of energy homeostasis in adult, as previously observed for the neonatal surge of the hormone leptin. Take advantage: aims at identifying novel metabolites able to activate IGN and test them as beneficial modulators of energy homeostasis under unbalanced nutrition. This will pave the way to novel therapeutic approaches of metabolic diseases based on IGN. Thus, the IGN project should lead to a better understanding of metabolic control and offer new perspectives for preventing metabolic diseases and maintaining healthy ageing.

Keywords: gut brain axis,glucose and energy homeostasis
Bioinspired cellular actuators (BiCeps)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Czechia,Slovakia,Austria
Call: EIC Pathfinder Open (HORIZON-EIC-2024-PATHFINDEROPEN-01, 2024)
Start date: 2025-03-01
End date: 2029-02-28
Duration (months): 48.0
Total project cost (EUR): 2894306.25
EU funding (EUR): 2894306.25
Participants: 5
Project status: SIGNED

BiCeps aims to revolutionize mechanical motion generation by designing, developing, and fabricating muscle-inspired actuators. These innovative microscale devices will be based on active cellular metamaterials capable of contracting in response of a stimuli, emulating the functional mechanisms of a remarkable biological actuator. This objective will be realized through the continuous integration of stiff structural materials with active stimuli-responsive counterparts. Multi-material additive manufacturing and allied technologies will allow the fabrication of artificial sarcomere, incorporating into 2D and 3D actuator arrays, and enabling macroscopic-scale contraction generating force through collective unit cell deformation. This groundbreaking approach overcomes the limitations associated with current active polymeric materials in soft robots, particularly their lack of structural stability. BiCeps aims to produce robust, enduring, and reliable actuators suitable for various technical applications, potentially replacing conventional electric motors and combustion engines in diverse sectors such as industrial, residential, and transportation. A critical priority for BiCeps is addressing the challenges associated with fabricating micro-architected cellular materials using high-strength materials. The risk involves uncovering optimal additive manufacturing, post-processing conditions and elucidate the principals of the actuator. The consortium's expertise in multi-material additive manufacturing will play a crucial role in ensuring precision and performance of muscle-inspired actuators. The potential market opportunities for these new actuators are immense. Even capturing a modest 1% of the global motor market could represent a significant investment opportunity, given the projected growth and value of the sector.

Keywords: mechanical actuator,cellular material,additive manufacturing