Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A climate neutral, sustainable and productive blue economy Parternship (SBEP)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: COFUND actions
Partnership: Climate neutral, sustainable and productive Blue Economy (co-funded)
Countries involved: Italy,Norway,Germany,Portugal,France,Spain,Belgium,Ireland,Romania,Sweden,Cyprus,Finland,Latvia,Lithuania,Netherlands,Türkiye,Estonia,Faroe Islands,Malta,Poland,Slovenia,Denmark,Greece,Iceland,Bulgaria,Tunisia,Georgia,Ukraine,Brazil
Call: Additional activities for the European Partnership for a climate neutral, sustainable and productive Blue Economy (HORIZON-CL6-2024-GOVERNANCE-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 105097886.25
EU funding (EUR): 31519166.0
Participants: 74
Project status: SIGNED

The proposal for additional activities for the European Partnership for a climate neutral, sustainable and productive Blue Economy Partnership (SBEP) responds to the Horizon Europe (HE) call HORIZON-CL6-2024-GOVERNANCE-01-1. Building on the work for enhancing the Strategic Research and Innovation Agenda (SRIA, updated version publication foreseen in spring 2024), 74 partners (+14 compared to the existing GA) from 29 (+4 compared to the existing GA) countries among Member States (MS), Associated Countries (AC) and Third Countries (TC), with the support of the EC will continue implementing the R&I programme together with comprehensive management activities to support the transformation of the blue economy, enhancing impact and building capacities as well as further structuring the ERA. In continuation with the existing Grant Agreement (GA), in its 2nd cycle, corresponding to the second instalment of the HE Work Programme, the Partnership will contribute to the Expected Outcomes of the topic HORIZON-CL6-2024-GOVERNANCE-01-02 by implementing two joint co-funded calls (in cash) together with a set of additional activities demonstrating European added valued to be carried out by deploying other type of assets. These entail: alignment of national thematic annual programming, alignment of monitoring programmes and sharing of research infrastructures through an open call for transnational access. As far as regards coordination and management activities, beside enhancing some existing tasks towards an increased impact, three new key tasks are foreseen on developing: (i) the Implementation Plan, (ii) thematic/regional portfolios (i.e. clusters) of projects supported through different HE calls as well as different programmes, (iii) future additional activities, e.g. on a European Ocean Observing System Knowledge Hub or an Early career PhDs network. In terms of priority areas, the new one on 'resilient coastal communities and businesses' adds to the four existing ones.

Keywords: sustainable blue economy,green deal,digital transition,innovative ocean governance,social transformation
Polar forest and atmospheric CO2 reconstruction during Earth’s last hothouse interval using multi-proxy strategies (POLARIS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Ireland,United States
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 252728.64
EU funding (EUR): 252728.64
Participants: 3
Project status: SIGNED

Fossil evidence from past warm periods reveals that tropical-like forests once extended well beyond the polar circles, creating a biome vastly different from today's Arctic. Due to the absence of modern equivalents, our understanding of the adaptations and structure of these ancient polar forests remains limited and often speculative. POLARIS will investigate a polar forest from Earth's last prolonged extreme greenhouse interval—the Early Eocene Climatic Optimum (ca. 53–49 million years ago). The project aims to reconstruct canopy structure, primary productivity and atmospheric CO2 levels in which the plants thrived, using state-of-the-art palaeobotanical and biogeochemical proxies, alongside cutting-edge models. Recent advancements in the field now enable us to address these questions, and our multi-proxy approach ensures verification of results, leading to reliable findings. This research will significantly advance understanding of past polar ecosystems and elucidate the role these forests played in global carbon cycling during extreme hothouse intervals. The findings will provide valuable data that could enhance the predictive power of climate models under various future climate scenarios. The project will be based at Trinity College Dublin, Ireland, with two secondments at the Smithsonian Institution and Wesleyan University, USA. This collaboration unites world-leading experts in palaeobotany and proxy development, providing the fellow with world-class training in a variety of research techniques and transferable skills. Additionally, the fellow will benefit from networking opportunities across two continents and hands-on experiences at different institutional types. This diverse exposure will position the fellow to become a future leader in the field.

Keywords: paleobotany paleobotanical proxies leaf traits biogeochemistry canopy closure atmospheric co2 primary productivity modelling fossil plants
Diagnosing skewed X-inactivation in women - Tandem Repeat-based Identification of X-chromosome Inactivation (TRiXi) (TRIXi)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Sweden
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2025-POC, 2025)
Start date: 2025-12-01
End date: 2027-05-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 2
Project status: SIGNED

Disease-causing mutations on the X-chromosome (‘X-linked’ disorders) typically only affect men. However, due to a genetic phenomenon called skewed X-inactivation (sXCI), thousands of girls and women in Europe also develop serious and often life-threatening X-linked disorders every year. As there is no reliable test for sXCI in humans, women carrying mutations are typically unaware of their risk, and when symptoms do develop, diagnosis is delayed. We have developed a method for quick, cheap and accurate detection of sXCI; Tandem Repeat-based Identification of X-chromosome Inactivation (TRiXi). We will take TRiXi from a cutting-edge research method to an in vitro diagnostic test for sXCI in female carriers of X-linked mutations. Following requests from clinical colleagues, TRiXi has been used to assess disease risk or confirm diagnoses for multiple life-threatening X-linked disorders in patients from Clinical Genetics Units across Sweden, confirming its real-world clinical utility and the unmet need for a standardized assay for sXCI in the clinic. TRiXi has additional commercial potential as a Research Use Only test kit to serve the large and expanding field of research into female medical health. I have filed a priority patent application for TRiXi, joined the business incubator at Linköping University, and assembled a team with expertise in business, patenting, and regulatory affairs to successfully translate my innovation. Over 1 million women are carriers of mutations for serious X-linked disorders, in Europe alone. This represents a large patient population requiring a better standard of care, that can be delivered by TRiXi, and a significant and largely untapped commercial potential. Over the next 18 months, we plan to: (i) establish a regulatory strategy for each market path, (ii) validate the unmet need through thorough market verification, (iii) continue IP protection, and (iv) finalize technical improvements/tests to prepare TRiXi for commercialization.
Carbon Initiative for Climate-resilient Agriculture (CARBONICA)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: North Macedonia,Cyprus,Greece
Call: Excellence Hubs (HORIZON-WIDERA-2022-ACCESS-04, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 4985250.0
EU funding (EUR): 4985250.0
Participants: 14
Project status: SIGNED

The continuous increase of the scope and the scale of the anthropogenic activities in which agriculture plays a significant role contributes to a rapid negative impact on the carbon cycle. The impact of agriculture on CO2 emissions will be further increased, considering that the world population will reach 9.7 billion by 2050 . EU has committed to mitigate the carbon footprint from agriculture as described in the CAP (Objective 4), the European Green Deal and its flagship strategies, the Farm to Fork and the Biodiversity strategies. The efficiency of these carbon footprint from agriculture strategies will be mainly determined by the synergy amongst all stakeholders (policy, industry, academia, civil society) in the quadruple helix within the place-based innovation ecosystems. The widening countries involved in this project, Cyprus, Greece and North Macedonia, as part of the Balkan-Mediterranean region, are heavily impacted by climate change. To achieve these targets an inter- and transdisciplinary approach is required to integrate the expertise and knowledge of all relevant stakeholders and a place-based perspective and design needs-based carbon farming solutions (practices and technologies) as well as strict policies to foster shifts towards a Climate-resilient Agriculture. The main objective of this project is to establish CARBONICA Excellence Hub by connecting the innovation ecosystems of Cyprus, Greece and North Macedonia, while enhancing their TRL as service providers, based on cutting-edge technologies (Earth Observation – EO; in situ data; digital agriculture etc.) in carbon farming. The main scope is to establish access to excellence to all relevant stakeholders in the QH of the WC, as well as strengthen regional innovation capacity guided by long-term joint R&I strategy in the carbon farming field.

Keywords: carbon footprint,agriculture,climate mitigation,carbon farming
Regionalised Trajectories and Socio-Political Transformations in the late 4th - early 3rd millennia BCE in Mesopotamia. (TRANSFORM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Portugal
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-10-02
End date: 2025-10-01
Duration (months): 24.0
Total project cost (EUR): 156778.56
EU funding (EUR): 156778.56
Participants: 2
Project status: SIGNED

The late 4th-early 3rd millennium BCE in Mesopotamia featured widespread changes, often cited as a period of societal collapse. TRANSFORM will explore the effect of this rapid change through close examination of pottery production at the site of Kani Shaie in the Kurdistan Region of Iraq (KRI). The key research question driving TRANSFORM is: To what extent are the major societal transformations during this period replicated in the production of pottery at Kani Shaie? Pottery production is the realisation of a set of social and technological choices. Thus, sudden changes to it– the likes of which are documented during this period at Kani Shaie – are socially and culturally significant. Thus, TRANSFORM will reconstruct the pottery manufacturing process across this transitional period, to investigate the effects of these societal transformations, and how the occupants at Kani Shaie adapted to them. This project will transcend traditional approaches by examining the social dimension of pottery production through application of a multidisciplinary methodology which seamlessly integrates archaeology, material science, geology, and anthropological theory. The researcher’s background and methodology uniquely place him to critically examine how localised trajectories underpin larger socio-cultural transformations. The project will benefit from the researcher’s cross disciplinary skills, combined with unprecedented access to an extensive archaeological dataset, and expertise at UC. In questioning the effect of the LC-EBA transition at Kani Shaie, TRANSFORM will produce significant results by highlighting the effect that local communities had upon, and how they were affected by supraregional cultural processes. This investigation presents an exciting opportunity to examine behavioural transformations when faced with major societal upheaval–a better understanding of which should give us pause to consider the ramifications of impending transformations facing us today.

Keywords: archaeology,material culture,mesopotamia,iraq,ceramics,early bronze age,late chalcolithic,kurdistan,material culture,thin section petrography,ftir
Data Cube and Copernicus data for Food Security and European Independence (Nostradamus)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Research and Innovation actions
Countries involved: Cyprus,Germany,North Macedonia,Serbia,Slovenia,Czechia,Italy,Ireland,Greece,Switzerland
Call: Open source solutions for edge, cloud and mixed model applications to strengthen production and administrative capacities in agriculture (HORIZON-CL6-2023-GOVERNANCE-01, 2023)
Start date: 2024-09-01
End date: 2028-08-31
Duration (months): 48.0
Total project cost (EUR): 4998667.5
EU funding (EUR): 4998667.5
Participants: 16
Project status: SIGNED

Nostradamus, in line with the Farm to Fork strategy, the Common Agricultural Policy, and the European strategy for data, will design, develop, and evaluate a scalable and robust platform for the online and real-time harvesting of valuable information derived from different data sources for developing several agricultural applications. Based on European and four national multidimensional datasets, an automated pipeline regarding the data acquisition, storage, and pre-processing, the developed platform will handle several open and commercial satellite datasets while employing in (near) real-time several server-side algorithms for time-series analysis and value-added geospatial maps. For enhancing the sustainability performance and competitiveness of the agricultural sector through a multi-actor approach, Nostradamus will develop a number of open-source-based digital applications for farmers considering both edge and cloud solutions, as well as a combination of the two, taking into account the potential of advanced Internet of Things solutions and Earth Observation data. Leveraging data from various sources that enable real-time data collection and analysis, farmers will be provided with actionable insights to optimize their operations and improve their yields, reducing agricultural inputs' utilization, which will boost EU resilience, independence, and ecological ambitions for agriculture. In addition, the systematic update of this data will strengthen the monitoring of the agricultural practices and the administrative capacities in this sector. Moreover, Nostradamus will adopt a multi-actor approach across the entire period of the project (workshops, field visits, training activities, etc.) that will continuously engage a variety of stakeholders, such as farmers, farm advisors, IT experts, and scientists, to reflect the knowledge, gaps, and needs of different groups properly and maximize the potential of deployment of the developed digital solutions and applications.

Keywords: green deal food security cereals digital solutions copernicus data open source digital applications internet of things edge cloud mixed solutions multi actor approach open call cap
Transport of Reaction Intermediates in the Stepwise Assembly of Fatty Acids (TRISAFA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-08-01
End date: 2024-07-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: CLOSED

Fatty acids are essential metabolites used in biological cell wall formation, energy storage, and signal transduction. Fatty acid synthesis is carried out in an iterative sequence of reactions, conserved across all species. Yet different organisms have developed different solutions, the most impressive is the fungal fatty acid synthase (FAS). The 2.6 MDa molecular complex integrates all enzymatic functions required for the stepwise assembly of fatty acids. Its architecture is reminiscent of a chemical nanofactory: The enzymatic domains face the lumen of the barrel-shaped complex, where nascent fatty acids are transferred between active sites by an integral acyl carrier protein (ACP). The function of the fungal FAS has long been in focus of research, not only due to its elaborate architecture but also because it is ideally suited as a platform for synthetic biology. Fatty acid derivatives are ideal precursors to produce biofuels or fine chemicals; and fungi are well adapted for industrial applications. Advances in experimental structural biology have established a framework for the progression of the synthesis cycle. However, the driving element is the transport of reaction intermediates by the ACP which is inherently dynamics. Thus, structures alone are insufficient for a mechanistic understanding of the fungal FAS function. TRISAFA aims to close this knowledge gap by integrating advances in structural biology with molecular dynamics simulations to resolve the pace and regulation of the transport process in atomistic detail. This approach will address three hitherto unanswered questions: First, how are the transport dynamics coupled to the conformational dynamics of the FAS? Second, how is the pace of the transport regulated? And finally, what factors determine termination of the fatty acid synthesis cycle. Ultimately, this project will yield a complete model for the progression of fatty acid synthesis, pivotal to their exploitation for biotechnological applications

Keywords: computational biophysics
Engagement in mHealth: Yoga-breath as a mental self-care and flourishing tool for adult cancer survivors (ENGAGE-M-BREATHER)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-04-01
End date: 2028-09-30
Duration (months): 30.0
Total project cost (EUR): 291145.2
EU funding (EUR): 291145.2
Participants: 2
Project status: SIGNED

The mental health (MH) burden of many adult cancer survivors (ACS) may persist for up to 26 years after cancer diagnosis, resulting in substantial psychosocial, professional, and economic losses. Digital mental health interventions (DMHIs) are a highly advantageous, sustainable, and state-of-the-art self-care solution for improving MH and quality-of-life of ACS. However, uptake of and adherence to DMHIs, jointly called engagement in digital self-care, is a persistent challenge in ACS. Developing more engaging DMHIs for ACS is one of the most promising solutions to tackle this challenge. Yoga-breathwork, which involves regulated breathing at one's own pace, is a good fit for many ACS as it is simple, cost- and time-effective, less intensive, evidence-based, and a self-manageable MH intervention that is scalable after digitalisation. Therefore, my MSCA-PF project, ENGAGE-M-BREATHER, aims to go beyond the state-of-the-art in digital self-care with innovative modalities for developing an engaging yoga-breath DMHI for ACS. ENGAGE-M-BREATHER is a uniquely positioned, ambitious project, which aims to develop and test novel engagement modalities for self-management of MH and flourishing in ACS through a yoga-breath DMHI. This central aim will be fulfilled by 1) co-creating a yoga-breath DMHI, 2) evaluating it for MH outcomes and offering related data visualisation analytics, and 3) exploring biofeedback coupling with the DMHI. Moreover, this project produces direct and immediate societal and technological outcomes during the non-academic placement by offering ACS a co-created DMHI to self-manage their cancer-related fatigue through an existing mHealth app, Untire. This market translation will also build more engagement in ACS. The interdisciplinary, international, and intersectoral exposure and training gained through this project will establish me as a leading researcher in digital MH, with the ability to form my independent research group with multinational grants.

Keywords: wellbeing,mental health,quality of life,self management,ehealth,health promotion,digital mental health interventions,mhealth,adult cancer survivors,co creation,biofeedback,yoga breathing