Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
O&M tools integrating accurate structural health in offshore energy (WATEREYE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Research and Innovation actions
Countries involved: Spain,Spain,Austria,Spain,Norway,Belgium,Netherlands
Call: Optimising manufacturing and system operation (H2020-LC-SC3-2019-RES-TwoStages, 2019)
Start date: 2019-11-01
End date: 2022-10-31
Duration (months): 36.0
Total project cost (EUR): 4709368.75
EU funding (EUR): 4709368.75
Participants: 9
Project status: CLOSED

Operation & Maintenance (O&M) costs are the main cost driver in offshore energy due to the difficult accessibility to the WTs, but also due to the environmental conditions. O&M costs can account for up to 30% of the levelised cost of energy (LCOE) and sensing & monitoring systems could help attain the expected fall to 70 EUR/MWh by 2030. The highest criticality (in €/kWh) in offshore wind is caused by structural failure, that mainly occurs due to corrosion processes non-adequately neither predicted nor monitored. For that reason, it is crucial to implement new monitoring, diagnosis, prognosis and control tools into the offshore wind farms (WFs) to enable Wind Farm Operators (WFOs) to take predictive smart O&M decisions fully considering structural components real and future status. WATEREYE aims to develop an integral solution that will allow to WFOs a 4% reduction of OPEX, accurately predicting the need for future maintenance strategy and increasing the offshore wind annual energy production. To this end, WATEREYE will: 1/ develop a monitoring system capable of remotely estimating the corrosion level in exact WT locations (tower, splash-zone, tower-platform junction) as a supporting tool for predictive maintenance to considerably reduce the O&M costs and reduce the risk for operation failures; New Ultrasound corrosion sensors (ad-hoc, low-cost, high accuracy, fast-response, non-invasive) will be developed, as well as high efficient and robust wireless communications specifically conceived for offshore WTs hard communicating environment. Besides, a novel drone-based mobile platform to move one mobile sensor inside the WT tower will be developed. 2/ develop enhanced prediction models by analysing the acquired data in novel ways (semantic models); 3/ develop WT & WF control algorithms with accurate consideration of the structural health, giving operators freedom to choose the best balance between energy production, protective control, and predictive maintenance.

Keywords: sensor,monitoring,diagnosis,prognosis,corrosion,models,condition based maintenance,predictive maintenance,corrosion monitoring,wind turbine control,wind farm control
Poultry manure valorization (Poul-AR)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Netherlands
Call: Boosting the potential of small businesses for eco-innovation and a sustainable supply of raw materials (H2020-SMEINST-1-2014, 2014)
Start date: 2014-10-01
End date: 2015-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Poultry farming worldwide is among the largest sectors of animal husbandry for food production. As with other bio-farming activities poultry farming is associated with manure production. In contrast with other manure types poultry manure is very rich in nutrients as nitrogen & phosphorus and also in organic material. The project applies eco-innovative principles and technologies and thus opens a sustainable route to nutrient recovery and energy efficiency for poultry manure. The approach makes use of subsequent biological and physical treatment steps. The 1st step in the process consists of a biological ammonification step in which organic nitrogen is biologically converted into ammonia. A 2nd step removes the ammonia present in the broth via stripping with air. The ammonia is subsequently fixated with sulphuric or nitric acid as an ammonium salt (sulphate, nitrate) to produce the desired fertilizer. The residual organic fraction of the manure can now be readily digested afterwards, to produce biogas which in turn can be used as a source of heat or electricity. The project proposes an integrated biological approach for the pre-treatment and valorisation of poultry manure. The liberation and fixation of nitrogen as nutrient is optimized and the product consists of a valuable ammonium salt directly applicable as fertilizer. The residue of the de-ammonification allows for a variety of post treatment methods. As a spinoff, additional amounts of valuable nutrients can be liberated and efficient bioconversion of the organic fraction comes within reach, adding to the potential of the business case. Meanwhile there is a significant environmental gain as the emission of ammonia into the atmosphere associated with current practices is completely prevented, which is especially beneficial for vulnerable and sensitive areas and water bodies. Up to 11.25 kg ammonia per ton poultry manure are released into the atmosphere when raw poultry manure is used for land fertilization.

Keywords: ammonification,de ammonification,nutrient recovery,poultry manure
Disrupting Aberrant Protein–Protein Interactions with Conformationally Constrained Hydrocarbon α-Helical Mimetics (DREAMY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-10-10
End date: 2020-12-20
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Many critical processes within cells, including those that control whether a cell lives and divides or dies, are mediated by protein–protein interactions (PPIs). In certain disease states, such as cancer, these interactions can become defective in a way where disruption of the interaction has therapeutic benefit. Replacement of one of the protein partners, which often have α-helical secondary structure, with a small molecule is one method of disruption; however, the interface can often be large and shallow, making the design of competitive small molecules challenging. The saving grace is that the interaction energy is usually dominated by the interactions of a few amino acid residues, which protrude from one or more faces of the α-helical peptide. The design of α-helical mimetics that are non-peptidic in nature and that can replicate the positioning of these hotspot residues has been an active area of research. The host laboratory has recently developed a method to prepare chains of substituted carbon atoms with complete control of absolute and relative configuration. Owing to the avoidance of syn-pentane interactions, the all-syn and alternating syn–anti contiguously substituted chains fold into well-defined helical and linear conformations. The positioning of the substituents could uniquely replicate a pattern of hotspot residues that cover two or more faces of an α-helical peptide. This project will explore this possibility through the design, preparation and testing of mimetics that target the Mcl-1/Noxa-B PPI, which controls apoptosis and has leucine, arginine, isoleucine, aspartic acid, and valine at positions 11, 12, 14, 16 and 18 as hotspot residues. The project merges cutting-edge synthetic organic chemistry, multiple forms of computation, including molecular mechanics, density functional theory, and molecular dynamics, NMR spectroscopy, and medicinal chemistry.

Keywords: drug discovery,inhibitors,protein protein interactions,synthetic methods,stereochemistry,molecular modeling,ligand and protein detected nmr,biochemical assay
High Voltage Aerospace Cable System (HIVACS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Germany,France,France,France,United Kingdom
Call: Development of AC cabling technologies for >1kV aerospace applications (H2020-CS2-CFP08-2018-01, 2018)
Start date: 2019-04-01
End date: 2021-07-31
Duration (months): 28.0
Total project cost (EUR): 853798.96
EU funding (EUR): 749833.5
Participants: 6
Project status: CLOSED

Current research and development is focusing on propulsive energy components for hybrid aircraft. This will open the path to an all-electrical aircraft. Power levels are predicted to be between 2 and 4MVA for hybrid systems and up to 40MVA for all electrical systems. This will require the transmission of electrical power across the airframe at previously unseen scales. This will not be possible without the development of power dense and safe cabling systems that operate at higher levels of voltage and current. To this end, the objective of HIVACS is to bring together a coherent suite of experimentally validated simulation models to permit the design exploration and optimisation of future aerospace cable systems to allow the aeronautical industry to meet the high-power design requirements of future aircraft programs. The project will also provide recommendations for future standardisation to the relevant standard committees and identify key axis for further development. After performing a state-of-the art review, a requirements and Failure Mode Effect and Analysis (FMEA) will be performed on the design and manufacturing processes on a selection of designs. A range of existing models will be used to assess the performance of these designs with these being adapted to the aerospace environment. The models will be validated by comparison to experimental test bench activities undertaken on existing cables. Once the models are qualified and accepted by NEXANS as being appropriate for adoption in an industrial setting, they will be used in a design optimisation process to determine optimal geometry and sizing of the candidate cables and predict their expected performance. With an optimum cable design, two cable types will be produced using different manufacturing techniques. Both will be tested and qualified. The project will draw upon existing test bench facilities and also develop a specific thermal test bench for thermal cycling ageing.

Keywords: partial discharge,high voltage ac cabling,electrical modelling,thermal ageing,simulation,standards,conductor and insulation screening,design optimisation,wrapping,high temperature extrusion
Security Management Platform for enhanced situation awareness and real-time adaptive evacuation strategies for large venues for sports and entertainment (evaGuide)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Belgium,Greece,United Kingdom
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2018)
Start date: 2018-12-01
End date: 2021-05-31
Duration (months): 30.0
Total project cost (EUR): 2392125.0
EU funding (EUR): 1674487.5
Participants: 4
Project status: CLOSED

evaGuide is a Security Management Platform for enhanced situation awareness and real-time adaptive evacuation strategies for large venues for sports and entertainment. evaGuide aims to address the needs of the safety of large facility visitors during complex evacuation processes, following normal and abnormal events (crises) towards the creation of an easily deployable system that will be able to timely identify new threats, designate and sustain a Location based Dynamic Evacuation Route (LDER) that improves all corresponding response times under any circumstances. Moreover it will support the complete lifecycle of evacuation planning, simulating complex scenarios, training of safety personnel and assessment of the performed actions. The results of the market research that has been performed among the 300 member stadia of ESSMA (the European Stadium & Safety Management Association) revealed that there is a clear need for a project like evaGuide that addresses all the phases of the evacuation lifecycle and offers superior situational awareness, while at the same time existing and emerging regulations from FIFA/UEFA need to be met. The business sustainability/exploitation potential has been validated in the Feasibility Study, which is an integral part of this proposal. The project outcome will be a fully functional evaGuide platform demonstrator delivered for operational use to one stadium (one of the ESSMA member stadia, selected on M2). The demonstrator will perform according to the adapted requirements defined by ESSMA and the stakeholders involved (finalized on M12), will be fully integrated (by M28) and tested (M29), ready to be commercially exploited by the joint commercialization entity defined during the last months of the project (M30).

Keywords: critical infrastructure,emergency systems,security,safety engineering,location based dynamic,evacuation route,safety,large crowded facilities,crowd simulation
Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes (TOBeATPAIN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Austria,Germany,Germany,Sweden,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2018-08-01
End date: 2022-07-31
Duration (months): 48.0
Total project cost (EUR): 2870359.2
EU funding (EUR): 2870359.2
Participants: 8
Project status: CLOSED

Damage to the central (CNS) and peripheral (PNS) nervous systems causes altered perception of pain (pathological pain) which is a common feature of diseases that have high prevalence in the European Union. Both increases and decreases in the ability to perceive pain impair both performance at work and quality of life. Pathological pain in neurodegenerative diseases, musculoskeletal diseases and peripheral neuropathies is associated with neuroinflammation, the inflammatory process whereby non-neuronal (inflammatory and glia) cells interact with neurones by releasing molecules that modulate pain signalling. TOBeATPAIN suggest that neuroinflammation represents an underlying mechanism of pathological pain states encompassing those with a PNS or CNS origin. The focus of this ITN will be on the mechanisms by which non-neuronal cells impact on neuronal activity in order to identify innovative non-neuronal targets for the treatment of pathological pain in peripheral macrophages or CNS microglia/astrocytes. TOBeATPAIN delivers high-level scientific and innovation-oriented complementary training, forging career pathways to increase inter-sectorial and transnational employability of young entrepreneurially-minded scientists in the academic and industrial sectors. It combines the expertise of 5 leading academic institutions, 2 pharmaceutical companies and 1 SME as Beneficiaries, together with 2 SMEs and 1 non-profit research charity as Partner Organisations, from 4 European countries. Fully aligned with the ‘Knowledge Triangle’ (business, research, higher education) platform, eleven ESRs will gain valuable knowledge and multidisciplinary skills through interdisciplinary research projects that integrate state-of-the-art technologies, supervision by and secondments to industrial Network organisations, Network-wide and local training activities, and specialized transferable skills focused in the acquisition of the ‘3-Knowledges’ (K-creation, K-exploitation, K-communication).

Keywords: chronic pain,neuroinflammation,neurodegeneration,painful peripheral neuropathies,musculoskeletal diseases,cytokines,chemokines,non neuronal cells,cb2 receptors,cx3cr1 receptors
Lifespan Inequalities: Why the age-at-death distribution varies between countries and socioeconomic groups (LIFEINEQ)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Germany
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-07-01
End date: 2023-06-30
Duration (months): 72.0
Total project cost (EUR): 1479105.0
EU funding (EUR): 1479105.0
Participants: 1
Project status: SIGNED

Individuals and populations are surviving to ever higher ages. A crucial and timely question for policymakers is whether to direct limited resources toward future life expectancy increases or toward reductions of inequalities in longevity. These inequalities, hereafter referred to as lifespan inequality but also known as age-at-death variation, are large, infrequently summarized, and impose major costs on individuals and society. In order to formulate effective policies to reduce lifespan inequality, we need a deeper understanding of the magnitude and causes of divergent age patterns of mortality decline. This project will undertake the most comprehensive inquiry to date into the development and anticipated future course of lifespan inequality in contemporary developed countries. Specifically LIFEINEQ has four main research objectives: (1) To quantify the recent and forecasted contributions of premature and old age mortality decline to changes in lifespan inequalities, (2) To determine the ages and causes of death that drive outlying age patterns of mortality, (3) To analyze the development of lifespan inequality by socioeconomic groups, and (4) To assess the impact of individual differences in behaviour on lifespan inequality. LIFEINEQ will tackle the above objectives using a combination of established and newly developed decomposition techniques, many of which were co-developed by the PI. These innovative techniques aim to isolate the ages, causes of death, periods, cohorts, and socioeconomic groups that propagate lifespan inequalities. The benefit to society is clear: a ground-breaking analysis of lifespan inequality could revolutionize the way that we conceive longevity. Just as economists have long summarized national income by the GDP and the Gini coefficient, so too will health experts summarize survival by life expectancy and lifespan inequality for a more complete picture of population health.

Keywords: mortality compression,life expectancy,lifespan variation,socioeconomic inequality,life tables,age patterns of mortality,decomposition
Boosting PhD employability @UCA (BoostUrCAreer)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Doctoral programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: France
Call: Co-funding of regional, national and international programmes (H2020-MSCA-COFUND-2018, 2018)
Start date: 2019-11-01
End date: 2024-10-31
Duration (months): 60.0
Total project cost (EUR): 2847600.0
EU funding (EUR): 1423800.0
Participants: 2
Project status: SIGNED

BoostUrCAreer project aims at implementing at Université Côte d’Azur (UCA) a multidisciplinary doctoral programme in e-health to attract to the French Riviera early-stage researchers (ESRs) with the world highest academic, creative and innovative potentials and to enhance their employability with the support from the Region Provence-Alpes-Côte d’Azur socio-economic dynamism. The proposed programme will foster interdisciplinary, intersectoral and international experiences with the objective of contributing to creating a new generation of PhDs equipped for both academic and non-academic careers in e-health and inclined to the great research and innovation challenges of tomorrow. In line with the strategy of excellence, interdisciplinary and innovation pursued by UCA, every doctoral project will have to associate two laboratories of UCA, a foreign academic partner and a non-academic one. BoostUrCAreer will thus provide a diversified education combining the most basic aspects of research with the practice of transfer toward other the socio-economic world. This dual expertise represents a real added value for career development and is acquired thanks to specific trainings on practical and transferable skills and a six-month mobility abroad at an international research laboratory. A close follow-up as well by two academic supervisors in fundamental laboratories and by an academic tutor and a local non-academic mentor will ensure the quality of doctoral theses and further facilitate the ESRs’ integration to the workforce. High-level applicants are selected through a merit-based, open and fair process to develop projects with UCA excellent research teams. They will receive an attractive allowance and dedicated research funds. BoostUrCAreer will promote European best practices for research and innovations and should serve as a model to disseminate these policies to the whole region.

Keywords: employability,interdisplinarity,international,intersectoral,career development,excellence,local attractiveness,phd programme,e health
platform-enabled KITs of arTificial intelligence FOR an easy uptake by SMEs (KITT4SME)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Italy,Spain,Germany,Spain,Italy,Italy,Italy,Italy,Italy,Italy,Poland,Switzerland,Finland,Croatia,Switzerland,Greece,Luxembourg
Call: I4MS (phase 4) - uptake of digital game changers (H2020-DT-2019-2, 2019)
Start date: 2020-10-01
End date: 2024-03-31
Duration (months): 42.0
Total project cost (EUR): 9213270.0
EU funding (EUR): 7999799.25
Participants: 20
Project status: SIGNED

KITT4SME specifically targets European SMEs and mid-caps to provide them with scope-tailored and industry-ready hardware, software and organisational kits, delivered as a modularly customisable digital platform, that seamlessly introduce artificial intelligence in their production systems. Uptake of the resulting packages and of the provided services is strongly supported by the clear characterisation and market readiness of the individual components as well as by the platform grounding on the already established RAMP marketplace. Leverage on the network of Digital Innovation Hubs, three of which are represented in the consortium, ensure that KITT4SME are widely distributed to a wide audience of companies in Europe. Seamless adoption of the customised kits is made possible by a Powered by FIWARE infrastructure that flawlessly combine factory systems (such as MES and ERP), IoT sensors and wearable devices, robots, collaborative robots and other factory data sources with functional modules capable to trigger data-driven value creation.

Keywords: smes,human factory symbiosis,data sovereignty,processes optimization,smart quality control