Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Chromatin 3D Structure of Archaic Human Populations and Its Impact on Modern Human Genomes (ARCH-3D)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom,Australia
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-10-01
End date: 2027-09-30
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 2
Project status: SIGNED

Most people alive today carry genetic material inherited from ancient hominins like Neanderthals or Denisovans. This introgression has shaped traits such as immunity, skin pigmentation, and disease susceptibility, yet the precise genetic mechanisms behind these influences remain unclear. Understanding how this archaic DNA continues to affect modern human biology could unlock new insights into both human uniqueness and diversity. While advances have been made in understanding the 3D structure of the genome and how genes are regulated spatially, the role of archaic DNA in these processes remains not fully understood. ARCH-3D aims to address this by constructing the first 3D models of Neanderthal and Denisovan genomes, offering a groundbreaking view of their spatial organisation. By comparing these models to modern human genomes, ARCH-3D will explore how introgressed regions influence gene regulation and contribute to human diversity. These regions may also reveal new targets for drug development, providing a practical application of the findings. Based at the McDonald Institute for Archaeological Research (MIAR) at the University of Cambridge, ARCH-3D will be conducted under the supervision of Dr. Guy Jacobs, an expert in human population genetics and archaic introgression. MIAR’s interdisciplinary environment, with its focus on human evolutionary genetics and archaeology, will provide invaluable resources for the computational analysis and interpretation of results in an evolutionary context. Dr. Wlasnowolski will also receive comprehensive training in cutting-edge computational techniques and interdisciplinary research, enhancing his academic career prospects. This experience will prepare him for roles in industries such as drug development, where understanding genetic mechanisms is essential, ultimately strengthening the impact of European science and industries like AstraZeneca, will advance European excellence and competitiveness in the field.

Keywords: human evolution,neanderthals,denisovans,chromatin,3d structure
Twinning to enable Baltic Sea vessels to meet Fit-for-55 regulations (BALTIC-FIT)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Panel: Environment and Geosciences
Countries involved: Estonia,Sweden,Finland
Call: Twinning Green Deal (HORIZON-WIDERA-2023-ACCESS-02, 2023)
Start date: 2024-09-01
End date: 2027-08-31
Duration (months): 36.0
Total project cost (EUR): 1563389.36
EU funding (EUR): 1499934.0
Participants: 4
Project status: SIGNED

The BALTIC-FIT project will build a network of excellence between organizations from Baltic Sea Region (Estonia as a Widening country, Finland and Sweden) to enable Baltic Sea maritime transport meet ‘Fit for 55’ regulations in decarbonisation. The BALTIC-FIT will achieve this goal by implementing a three-year Innovation strategy comprising five objectives, which are focused on strengthening the TTU’s position in the field of maritime decarbonization. This strategy includes short-term staff exchanges of senior and young researchers, 3 thematic summer schools; organization of innovation workshops for industrial and maritime stakeholders; attendance of external events; publication of joint open-access research articles and professional articles. To strengthen the research management skills of TTU, a specific work package integrates a comprehensive approach including (1) multi-hour mentoring programme focused on preparation of Horizon Europe proposals and (2) training workshops on proposal writing, research management, project administration, research dissemination and communication and IP management. In the frame of the joint innovation project the partners will concentrate efforts on the decarbonization of the shipping in Baltic Sea region, which has specific constraints in terms of operations, and will deliver recommendations for authorities and private business companies on how to tackle the pressing issue of decarbonisation. The authorities will have more understanding the opportunities that business sector has in GHG-emission reduction and private sector will learn about operational (TTU), technical (VTT) and digital (RISE) aspects of shipping. By enhancing collaboration between Baltic maritime stakeholders, BALTIC-FIT will cultivate a comprehensive understanding of the sustainable maritime practices, guiding the region towards environmental sustainability aligned with “Fit for 55' package and contributing to the success of the European Green Deal.

Keywords: maritime industry,shipping industry,low carbon emission vessels,digitalization in shipping and logistics,energy efficiency,port operations
Rectifiability and Density in Carnot and Homogeneous Groups, and Applications to Partial Differential Equations (RaDiCHAPDE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: CLOSED

The core of this project is Geometric Measure Theory (GMT) in Homogeneous Groups. The PI suggests exploring exciting original research avenues regarding the interplay between the concepts of flatness, density, and regularity of measures, and their applications to the theory of Partial Differential Equations (PDEs) and Free Boundary Problems (FBPs) in non-Euclidean spaces. The project’s potential for groundbreaking discovery is achieved by focusing on the investigation of i) the extension of the very classical density problem, whose solution in Euclidean spaces is codified in the celebrated Preiss' rectifiability theorem, to parabolic and Kolmogorov spaces; ii) the quantitative Reifenberg Theorem for measures in the parabolic space and quantitative dimensional estimates of the mutual singular set for the caloric measure in a two-phase problem; iii) the interplay between differentiability of Lipschitz functions and fine geometric properties of Radon measures in general Homogeneous Groups. As a byproduct of the study of iii), it will be obtained a converse to Pansu's Differentiability Theorem.

Keywords: geometric measure theory,preiss s rectifiability theorem,free boundary problems,homogeneous groups
PracticE Ecosystem for standaRdS (PEERS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Disaster-Resilient Society for Europe
Action type: Coordination and support actions
Countries involved: Ireland,Italy,Czechia,Hungary,Belgium
Call: Developing a prioritisation mechanism for research programming in standardisation related to natural hazards and/or CBRN-E sectors (HORIZON-CL3-2021-DRS-01, 2021)
Start date: 2022-11-01
End date: 2025-10-31
Duration (months): 36.0
Total project cost (EUR): 1999075.0
EU funding (EUR): 1999075.0
Participants: 9
Project status: SIGNED

The overall objective of PEERS is to advance and reinforce existing policy through practitioner-driven pre-normative standardisation processes, which will enhance the development of a European Better Practice ecosystem. The project aims to support the effective strengthening of preparedness and response in the field of DRR and CBRN-e through standardisation. The ecosystem brings together Europe's disaster risk management for natural hazards and CBRN-E and European research policy-making, societal stakeholders standardisation bodies, and industry stakeholders to strengthen European resilience to all hazards through a comprehensive engagement and consultation governance mechanism.

Keywords: pre standardization,co creation,stakeholders engagement
Technologies for Extreme Environment Observation and Research (EXPLORER)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,France,Czechia,Spain,Denmark,United States,Brazil,Australia,Chile,Japan
Call: MSCA Staff Exchanges 2024 (HORIZON-MSCA-2024-SE-01, 2024)
Start date: 2025-11-01
End date: 2029-10-31
Duration (months): 48.0
Total project cost (EUR): 671340.0
EU funding (EUR): 656310.0
Participants: 16
Project status: SIGNED

The ambitious objective of the EXPLORER project is to develop, validate and use pioneering portable, robust and user-friendly photonic technologies for investigating in situ harsh natural environments, characterized by extreme temperatures, and remote or inaccessible natural locations. These cutting-edge solutions aim to enhance our understanding of natural and fragile ecosystems, contributing crucial insights into topics such as climate change and ecology which constitute a priority at a European and global level. Conventional practices foresee sample collection and transportation for subsequent laboratory analysis, which introduces unavoidable alterations to specimen functionality and prevent the study of its interactions with original ecosystems, limiting current investigation capabilities. Here we will develop new tools that, for the first time, will be usable both in situ and by non-expert endusers, which, overcoming current time-consuming and invasive procedures, will enable new discoveries and fundamental investigations. To tackle this multi-disciplinary endeavor, the EXPLORER consortium will leverage different and complementary expertise in micro-nano fabrication, photonics, electronics, data analysis, and biology. We will demonstrate the versatility of the proposed technologies applying them to highly different environments, including hot springs in volcanic regions, glaciers as well as deep lake beds and contaminated settings. Improving our knowledge on these environments offer an incredibly wide range of applications, which span from climate change monitoring through fragile ecosystem analysis to environmental poisoning evaluation and ambitiously even volcanic eruption prediction.

Keywords: harsh environments,sensors,natural ecosystem investigation,spectroscopy,portable technologies,lab on a chip
Laboratories of Humanitarianism: Aid, Intervention, and the End of the Soviet Union, 1985-2000 (LabHum)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-05-01
End date: 2031-04-30
Duration (months): 60.0
Total project cost (EUR): 1499162.5
EU funding (EUR): 1499162.0
Participants: 1
Project status: SIGNED

Laboratories of Humanitarianism is a ground-breaking history of the Soviet collapse that explores the transformative impact of humanitarian crisis on the country’s disintegration and the reconfiguration of the post-Soviet world. To explore this impact, the project takes a panoramic approach and explores humanitarianism at multiple scales using case studies from across the vast territory of the Soviet Union. At the heart of the project is one fundamental question: What is the role of humanitarian action in contexts of state collapse and reconstitution? To answer this question, the project brings together a multilingual and dynamic research team to explore the impact of humanitarian intervention in Armenia, Kazakhstan, Ukraine, and Russia. Laboratories of Humanitarianism provides a radical rethinking of the Soviet collapse—arguably the formative geopolitical moment for understanding modern Eurasia. It moves beyond the realm of high politics to place the chronically under-researched themes of health and welfare at the centre of the analysis and provides an innovative methodological framework for writing new, transnational histories of the Soviet disintegration that foreground the country’s linguistic, cultural, and environmental diversity and that respond to contemporary challenges associated with archival access. In focusing on the Soviet and post-Soviet world, this project will upend assumptions within the modern history of international humanitarianism, where the timelines, perspectives, frameworks, and ‘watershed moments’ of North America and Western Europe have tended to be taken as normative. The USSR and its successor states provide a unique vantage point for exploring the relationship between donor and recipient of aid, as well as role of the ‘Second World’ in the development of global humanitarian regimes and practices in the late twentieth century.

Keywords: humanitarianism humanitarian aid soviet union
Economy bY spacE (SNLS-EYE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: MSCA other
Action type: Coordination and support actions
Countries involved: Italy
Call: HORIZON-MSCA-SNLS-2021-IBA (HORIZON-MSCA-2021-SNLS-IBA, 2021)
Start date: 2022-01-01
End date: 2025-06-30
Duration (months): 42.0
Total project cost (EUR): 46964.29
EU funding (EUR): 32875.0
Participants: 1
Project status: CLOSED

The Marie Skłodowska-Curie actions pay particular attention to physical accessibility and inclusion and foresee financial support for the additional costs entailed by recruited or seconded researchers with disabilities.

Keywords: economy and ephidemic modelling,artificial intelligence,remote sensing,cute posterior multifocal placoid epithelopathy
eCAP - Ehealth CAPsule for digestive disease diagnostics and therapy (eCAP)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Unlocking the full potential of new tools, technologies and digital solutions for a healthy society
Action type: Innovation actions
Countries involved: France,Ireland,Kenya,Ukraine,United Kingdom,Czechia,Netherlands
Call: Smart medical devices and their surgical implantation for use in resource-constrained settings (HORIZON-HLTH-2021-TOOL-06, 2021)
Start date: 2022-05-01
End date: 2026-04-30
Duration (months): 48.0
Total project cost (EUR): 5611654.54
EU funding (EUR): 4757957.9
Participants: 11
Project status: SIGNED

eCAP aims to deliver a novel medical device which combines a smart capsule with an e-health platform for better diagnostics, patient empowered disease management and hence, improved outcomes for patients with gastrointestinal (GI) diseases. Our project will create a modular and implantable capsule with multi-sensing capacity that enables GI physiology monitoring for a controlled time period, leveraging the minimally invasive surgical approach of flexible endoscopy. eCAP will use a worldwide ubiquitous smartphone communication standard, together with cloud computing technology and application interfaces to integrate, process and interpret longitudinal physiological data collected by the capsule. The digital platform is designed to improve the accuracy and clinical usefulness of standard test data by incorporating patient reported outcome measures. The clinician is able to personalize the test for the patient and receive accurate and meaningful results from this multi-stream data input with interpretation aided by Artificial Intelligence. The universality of the eCAP solution will allow dissemination of advanced GI disease diagnostics to patients and doctors worldwide, including low resource environments. During the project, we will demonstrate eCAP?s clinical value and cost savings using gastroesophageal reflux disease (GERD), a worldwide, common, and extremely costly problem, as a clinical target. Clinical evaluation with health-economics analysis will be conducted in France, Ukraine and Kenya, and a specific education program will be developed to train practitioners to use the novel technology. eCAP builds on several years of R&D by our consortium in the field of implantable capsules for GI disease diagnostics. Its ambition is to facilitate a shift in GI diagnostics from its current unscalable analogue version to a patient centered e-health tool and to make Europe the leader in the rapidly growing field of connected medical devices for remote patient monitoring.

Keywords: smart capsule,bluetooth,gerd,gi,endoscopy
Health, safety and ErGOnomics for the future human-centric factory (HEGO)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Italy
Call: Women TechEU (HORIZON-EIE-2021-SCALEUP-01, 2021)
Start date: 2022-06-01
End date: 2022-11-30
Duration (months): 6.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

MSDs are inflammatory and/or degenerative ailments affecting all sectors and all categories of workers, and are by far the most common work-related health problem in the European industry. The biggest Europe-wide occupational health survey found 46% of European workers reporting back pain, while 43% had painful shoulder, neck and upper limb muscles. The social and economic consequences of this “pandemic” are now becoming clear: • MSDs accounted for 53% of work-related diseases in the EU-15, affecting 100 million people and causing half the absences from work and 60% of permanent work incapacity. • Total cost of lost productivity attributable to MSDs is 2% of gross domestic product in the EU (€240 billion). HEGO is an innovative solution based on a proprietary set of Motion Capture algorithms able to recognize the workers’ gender, age, posture and movements in real-time and monitor ergonomics to adapt both workspace and workload according to worker’s personal profile, to inform about potential MSDs risks, and to provide insights for improving the work environments. Without the use of wearable devices and thanks to an automatic analysis of ergonomic risk factors, HEGO can detect any incorrect posture of the worker or risky situations, suggesting to operators the corrective actions. The performance of the system is outstanding and has been validated in industrial facilities: accuracy in recognition of skeleton points and movements > 85%; true positives and true negative in the recognition of an incorrect posture > 90%; data synchronization times < 0.5 sec. HEGO contributes to promote health and safety in industrial workplaces (Human-centered manufacturing concept) by providing a low cost and reliable solution.

Keywords: motion capture models health and safety in industrial facilities musculoskeletal disorders in workplace promotion of active aging
Demonstration of a sustainable circular-by-design manufacturing system based on additive manufacturing (DIAMETER)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Made in Europe (co-programmed)
Countries involved: Türkiye,Sweden,Germany,United Kingdom,Spain,Greece,Italy,Belgium,Australia,Cyprus
Call: Technologies/solutions to support circularity for manufacturing (Made in Europe Partnership) (RIA) (HORIZON-CL4-2024-TWIN-TRANSITION-01, 2024)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 5999845.0
EU funding (EUR): 5999845.0
Participants: 18
Project status: SIGNED

DIAMETER aims to facilitate the implementation of a circular economy within the metal manufacturing sector through the development of hybrid manufacturing systems based on additive manufacturing. The Consortium will develop a set of digital tools to improve the design, optimise the manufacturing process and ease the implementation of circularity strategies (remanufacturing, refurbishing, repairing and recycling) by the additive manufacturing industry. To support those tools, we will develop a novel AI-assisted algorithm able to calculate both the ecological and economic impacts of a process to assess its sustainability. This AI-assisted algorithm will rely on experimental data, from process monitoring and part characterisations, and process simulation, covering pre-processing machining, additive manufacturing and post-processing machining. We will integrate these tools into a first platform, called DIAgonal, to facilitate the uptake by the industry. The platform will integrate the European Digital Product Passport by enabling the use of supplier data for more accurate ecological impact estimations and allowing the upload of experimental data to enrich product transparency on origin, materials, and recyclability. We will develop a second platform, DIAdemia, to support the upskilling of the workforce through interactive training courses, workshops, and exercises. Overall, DIAMETER will contribute to reducing the manufacturing sector's carbon footprint, enhancing recycling, developing a greener Industry 4.0 and promoting local production.

Keywords: circularity,additive manufacturing,process,sustainability,machining,industry,digitalisation