Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
New Strategies for Bond Activation and Catalysis with subvalent Main Group Complexes (cAAC-Light)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 163099.2
EU funding (EUR): 163099.2
Participants: 2
Project status: CLOSED

This proposal aims to explore the feasibility and scope of thermal and light-driven bond activation and catalysis by sub-valent group 14 Main Group (MG) systems stabilized by highly σ-donating cAAC (cyclic (alkyl)amino carbene) ligands, exploiting their reduced HOMO-LUMO energy gaps, including MG-cAAC complexes, directly bonded MG/TM ( TM = transition metal) species and unprecedented hybrid MG/TM systems. We will initially target exotic cationic MG-cAAC complexes to investigate their capacity towards the activation of common E—H bonds (e.g. silanes, boranes or amines,including ammonia), including reversibility studies. This will be followed by exploring the activation of more challenging substrates, particularly the oxidative cleavage of C—H bonds. To enhance the capacity of activating less reactive bonds (e.g. intermolecular C—H, C—X…), as well as to enable more accessible reversibility routes (e.g. reversible H2 activation), we will target a variety of cooperative systems that will rely on the synergistic action of a MG element and a TM in close proximity. Investigating these synergistic effects will set the basis for designing more efficient systems in the search for innovative cooperative catalysis. In particular, this approach will permit the low-valent MG element to act as the activator, while the TM in close proximity may provide additional mechanistic routes for further functionalization. In the long term, we expect that our novel strategy will provide solid grounds for further developments in the vivid areas of low-valent MG chemistry and in particular in their use as catalysts for challenging transformations.

Keywords: main group,cooperative catalysis,germanium
Sounding the Depths of Providence: Mineral (Re)generation, Natural Resources, and Human-Environment Interaction in the Early Modern Period (SOUNDEPTH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-09-01
End date: 2024-08-31
Duration (months): 36.0
Total project cost (EUR): 251002.56
EU funding (EUR): 251002.56
Participants: 2
Project status: SIGNED

SOUNDEPTH is a research project on early modern conceptions of ore generation within the broader theoretical and practical contexts of natural philosophy, Earth sciences, and human-environment interactions. In carrying out an interdisciplinary study of these subjects, the project aims to disclose new insights into our understanding of geological phenomena and natural resources, thus giving a significant contribution to the history of science, environmental history, and to the ongoing environmental debate. These goals will be achieved through the acquisition of new scientific knowledge and skills, the strengthening of the existing ones, and the implementation of an interdisciplinary work that will combine 1) an in-depth analysis of the sources that influenced the early modern debate on mineral generation and 2) a confrontation with the existing secondary literature on the subject, with 3) the replication in laboratory of significant alchemical and mineral processes and the comparative exploration of historical mining sites in Europe. The outgoing phase at Johns Hopkins University (USA, month 1-24) will focus mainly on the analysis of sources and studies, on the acquisition of new scientific knowledge (geochemistry, geobiology, alchemy, experimental history of science), and on laboratory replications. The secondment period at Radboud University Nijmegen (Netherlands, month 25-27) and the incoming phase at Ca’ Foscari Venice (Italy, month 28-36) will be especially devoted to refining my existing expertise (history and philosophy of early modern science, Earth sciences, environmental history, ecology, digital humanities, textual criticism) and to the exploration of historical mining sites. Research outputs (conference presentations; open access, peer-reviewed publications; open data repositories; outreach and communication activities; publications aimed to students and the general public) will be produced across the entire duration of the project.

Keywords: history of science,natural philosophy,earth sciences history,early modern period,environmental,studies,natural resource management,mining,human environment relations,interdisciplinary
Modulation of Basket cell microcircuits in cerebellar cortex paroxysmal ataxia disorders (BaskAtax)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-10-01
End date: 2019-09-30
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The episodic ataxias are a group of hereditary conditions with recurring paroxysms of cerebellar dysfunction. They are rare; however they share important similarities to other more prevalent paroxysmal disorders such as migraine and epilepsy. The prototypic cerebellar cortex paroxysmal disorder is Episodic ataxia 1 (EA1), which is linked to dominantly inherited missense mutations in the Kv1.1 potassium channel subunit. Work from an animal model harbouring a human EA1 mutation reveals altered synaptic function at basket cell terminals in the cerebellar cortex. However how EA1 mutations affect basket cell regulation of Purkinje cell firing is unclear, possibly due to unforeseen changes in a specialized inhibitory structure called the pinceau. Furthermore the mechanism whereby local synaptic deficits extend to global cerebellar cortex network dysfunction during attacks of incoordination is unknown. This MSC research action aims to understand these processes using a combination of cutting edge in vitro and in vivo techniques. Using advanced electrophysiology techniques, I will assay basket cell pinceau function in mouse models of EA1, then using multi-photon and conventional microscopy I will map local basket cell microcircuits. Finally building on in vitro experiments I will assay candidate small molecule therapies in vivo, both with electrophysiology and with behavioural test of cerebellar coordination. The project allows me to train in state-of-the-art in vitro and in vivo methods while drawing on my extensive background in neuropharmacology, biochemistry electrophysiology. This research action will also advance our understanding of paroxysmal neurological disorders and identify new therapeutic targets.

Keywords: paroxysmal neurological disorder,episodic ataxia,basket cell,cerebellum
The cleanest and lowest cost car ever! (SOFTCAR)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Switzerland
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2018-04-01
End date: 2018-07-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Despite electric vehicles (EVs) are being promoted worldwide to decarbonize the transport sector and depollute city centers, the EVs industry is still facing several challenges which hampers the market deployment: 1) Technical: All cars are manufactured based on stamped steal-based chassis, making it very difficult to reduce the vehicle weight, which is the main hurdle for EVs. 2) Economic: Manufacturing lines are heavily automatized, hence with high capex and little employment. 3) Environment: The car manufacturing process has a huge environmental impact at each phase of the lifecycle (production, use, end of life). SOFTCAR SA is a Swiss start-up, founded by a team of 3 experts in the field of EVs who is now bringing to the market a high performance, highly competitive 4-seater battery EV, which offers the lowest possible ecological footprint while offering the same safety and performance level as other EVs. The Softcar paradigm shift in car conception and manufacturing translates into breakthrough economic added value and key product differentiation in three main areas: 1) Sustainable materials: The vehicle architecture is based on massive use of bio-plastics and advanced composite materials that reduce the vehicle weight by 2.5 compared to classical car. 2) Disruptive architecture: Softcar reduces the number of parts from 40,000 in classical EVs to 1,800, lowering the production costs from €15,000 for conventional EVs to €9,000 for Softcar. 3) Breakthrough manufacturing: There are only two automated process (Rotomoulding and GMT), implying that a low capex small-size plants can be viable from capacities of 5,000 vehicles per year (about 40 times lower than classical automotive industry). The total capex requirement is €17 million, the pilot plant reaches capacity (5000 unit/year) 5 years after start of production, while the cumulated cash flow breaks even just after 2 years and reaches €88 million at 4th year, corresponding to an IRR of 132%.

Keywords: low environmental footprint,low cost,zero emissions,eco design,mobility,electric vehicle,bioplastics,transport
REliability and Safety Engineering and Technology for large maritime engineering systems (RESET)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Finland,China,Malaysia,Thailand,United Kingdom,Portugal,United Kingdom
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2016, 2016)
Start date: 2017-05-01
End date: 2023-02-28
Duration (months): 70.0
Total project cost (EUR): 1417500.0
EU funding (EUR): 1282500.0
Participants: 9
Project status: CLOSED

Failure of large complex engineering systems often leads to catastrophic consequences. Their efficient and safe design and operation will avoid or reduce malfunctions, failures and accidents, which would have a significant impact on the daily life of the public in terms of service and product delivery, business interruption, economic losses, human injuries/fatalities, and property and environmental damage. The proposed project aims to develop and apply knowledge in Reliability and Safety Engineering and Technology (RESET), for safe and reliable design and operation of large maritime (marine and offshore) and other made-to-order (MTO) engineering systems. This multi-disciplinary and inter-disciplinary project of 48 months’ duration, will formulate a consortium of complementary expertise targeting areas of academic and industrial importance. In particular, a series of integrated activities will investigate i) the framework for reliability and safety assessment, ii) system risk and reliability modelling under uncertainties, iii) fluid and structural modelling under uncertain environments, iv) fatigue and fracture assessment, v) decision making together with case studies, and vi) the development of guidelines for general application of the developed models. The engineering systems that are addressed in this project include: a) ships, b) offshore installations, c) offshore wind farm units and d) other MTO engineering structures/units. In order to achieve an integrated project, all the ESRs and ERs involved will conduct their model development and application within the RESET framework. Novel and flexible models for addressing the identified research needs will be developed for application in situations where conventional approaches may not be confidently applied due to incompleteness, randomness and fuzziness of the available data for use in reliability and safety analysis. The collaboratively produced research results will be disseminated to a wide audience.

Keywords: safety assessment,reliability assessment,risk based decision making
Ocean Artificial Upwelling (Ocean artUp)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Germany
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2017-01-01
End date: 2021-12-31
Duration (months): 60.0
Total project cost (EUR): 2499991.26
EU funding (EUR): 2499991.26
Participants: 1
Project status: CLOSED

The productivity of the ocean is limited by the transport of nutrient-rich deep waters to the sun-lit surface layer. In large parts of the global ocean this transport is blocked by a temperature-induced density gradient, with warm light waters residing on top of heavier cold waters. These regions, which are referred to by scientists as ocean deserts, are presently expanding due to surface-ocean warming. Enhancing the upward transport of nutrient-rich deep waters through artificial upwelling can break this blockade and make these waters more productive. Forced upwelling of deep-ocean water has been proposed as a means to serve three distinctly different purposes: (1) to fuel marine primary production for ecosystem-based fish farming; (2) to enhance the ocean’s biological carbon pump to sequester CO2 in the deep ocean; (3) to utilize the surface to deep-ocean temperature gradient to generate renewable energy via Ocean Thermal Energy Conversion (OTEC). Whereas theoretical and technical aspects of applying artificial upwelling for these purposes have been studied to some extent, the ecological responses and biogeochemical consequences are poorly understood. Ocean artUp therefore aims to study the feasibility, effectiveness, associated risks and potential side effects of artificial upwelling in increasing ocean productivity, raising fish production, and enhancing oceanic CO2 sequestration. This will be addressed through a combination of experiments at different scales and trophic complexities, field observations of eddy-induced upwelling in oligotrophic waters, and ecosystem-biogeochemical modelling of pelagic systems fertilized by nutrient-rich deep waters. If technically feasible, ecologically acceptable, and economically viable, the use of artificial upwelling for ecosystem-based fish farming could make an important contribution to an ecologically sustainable marine aquaculture.

Keywords: marine ecology and biogeochemistry,marine food production,fish farming
Reversed-polarity III-nitride Sensors for Enhanced UV-detection (ReSensE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland,Japan
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-07-01
End date: 2023-11-28
Duration (months): 36.0
Total project cost (EUR): 283056.96
EU funding (EUR): 283056.96
Participants: 2
Project status: SIGNED

Smart, enhanced detection of ultraviolet (UV) radiation will be a key enabling technology for many forthcoming technological revolutions in fields such as industrial processing, space research, defence and medicine. AlGaN alloys with high Al content are the perfect materials for this type of device. By varying their composition, the absorption edge can be precisely controlled across the whole UV range down to wavelengths as short as 200 nm. AlGaN-based photodetectors are fast, with very low dark currents, highly biocompatible, and chemically stable. However, two main problems limit their development: the difficulty in achieving satisfactory p-type doping, and the presence of polarization fields that disrupt the internal electric field and make it difficult the separation of the photo-generated carriers. This project aims to use N-polar AlGaN materials to tackle both problems. This material orientation has proved to favour incorporation of p-type impurities and induce higher electric fields for carrier separation. Different Metal Organic Vapour Phase Epitaxy (MOVPE) growth conditions will be studied to control the growth of N-polar AlN templates and magnesium doped AlGaN epilayers. Finally, a prototype of solar-blind UV photodetector based on AlGaN/AlGaN heterostructure will be grown, fabricated and fully characterized. In order to pursue this project, the fellow will carry out the outgoing phase at Nagoya University, Japan, under the join supervision of Prof. Hiroshi Amano and Prof. Markus Pristovsek for a period of 21 months. He will then return to the Tyndall National Institute in Cork, Ireland, for the final 12 months under the supervision of Prof. Peter Parbrook. At the start of this project the candidate will also carry out an initial 3-month secondment period in a company that specialises in sensors to perform a preliminary simulation study and gain better understanding of the industrial requirements for a possible future commercialization of these devices.

Keywords: iii nitride materials,algan,movpe
Metamaterial based, radio frequency and millimetre wave phase shifters for future generation phased array antenna applications (SMARTWAVE)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Emerging themes and communities
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Greece,Belgium,France
Call: EIC Transition to Innovation Activities (H2020-EIC-FETPROACT-2019, 2019)
Start date: 2020-09-01
End date: 2023-04-30
Duration (months): 32.0
Total project cost (EUR): 1888550.0
EU funding (EUR): 1888550.0
Participants: 5
Project status: SIGNED

In the modern world everything goes wireless and everyone goes mobile. To sustain this trend, higher frequency, smaller, more complex analogue electronics with beam steering capabilities are becoming ubiquitous. SMARTWAVE capitalizes on a newly identified technology combination to reinvent, design, fabricate and commercialize the main building block of any beam steering capable system, the phase shifter. A novel phase shifting mechanism based on reconfigurable metamaterials promises to enable phase shifting technology with excellent performance characteristics, increased speed and reduced power consumption. SMARTWAVE technology is easily implemented in existing semiconductor fabrication lines and is inherently compatible with both III-V as well as Si and SiGe fabrication process. This ensures easy adoption of the novel idea into existing markets. To prove this, SMARTWAVE aims at demonstrating the phase shifting prototype in both technological platforms building a III-V based, K-band version to be included in a demonstrator phase array antenna for Satcomm and / or Radar applications as well as an advanced radar chipset fabricated in SiGe BiCMOS technology operating at 120GHz. SMARTWAVE capitalizes on that technology and an agile consortium made of 1 large company, 3 SME’s with unique high tech knowledge and an academic partner with extensive III-V fabrication experience in radar modules to provide a fast track to commercialization from the design board all the way to Radar and Satcomm systems.

Keywords: metamaterials,fets,iii v,sige,reconfigurable antenna,high frequency,mmwave,rfic,microwave devices,nano rx,tx modules,radar,satcomms
Infrastructural Challenges in Smaller African Cities: Digital Technologies and Water Infrastructure for Sustainable Towns? (IcSAC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-01-04
End date: 2023-08-06
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: SIGNED

‘Infrastructural Challenges in Smaller African Cities...’ is an innovative research project into water and digital infrastructures in smaller cities in sub-Saharan Africa. It examines the growing adoption of digital technologies in water infrastructure, an emerging phenomenon across urban Africa that remains under-investigated. It focuses on the dynamic and vibrant context of smaller cities in sub-Saharan Africa, which are experiencing accelerated urban growth but continue to be neglected in urban and infrastructure academic research. Examining water and digital infrastructures in two smaller Lusophone cities in Africa – Nampula, Mozambique and Bissau, Guinea-Bissau – will establish new, in-depth understandings of the infrastructural challenges, models and solutions emerging in smaller cities. In this way, this research will contribute to broader theorisations of infrastructure and African cities by bringing into these debates the experiences of a diversity of cities. This project will also shed light on the emerging social, political and material implications of the growing adoption of digital water technologies, and on the modes of urbanity specific to smaller cities. It will produce findings relevant to policy debates and Sustainable Development Goals 6 and 11. The research will adopt an innovative mix of qualitative methods, including mobile methods and ‘water biographies’. Novel user engagement and dissemination strategies will facilitate the engagement of different academic and non-academic audiences. Supervision by a world expert with networks across the Francophone and Anglophone academic worlds (Professor Sylvy Jaglin at LATTS), the opportunity to work in the Francophone research context, and an institutional visit to a research centre in Portugal (the Centre for Social Studies in Coimbra) will maximise this project’s ambition to strengthen links and shape conversations on urban research across literatures and scholarly networks.

Keywords: urban infrastructure,water,digital technologies,african cities,secondary cities,states