Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Deep learning AI in cancer diagnostics (AiforCancerDX)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Finland
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-11-01
End date: 2022-04-30
Duration (months): 30.0
Total project cost (EUR): 2930000.0
EU funding (EUR): 2051000.0
Participants: 1
Project status: CLOSED

Aging populations and increasing cancer rates are increasing the number of samples in healthcare. Despite the growing trend of digitalisation, pathologists are still reviewing the samples manually, which is a subjective, time-consuming, expensive manual process that exposes patients to the risk of misdiagnosis. Thus, there is a clear need for an affordable tool that supports and streamlines the workflows of pathologist, complementing humans with automated and objective analysis. Aiforia® Cloud platform augments the efficiency and consistency of a pathologist’s clinical workflow. It removes the slow and inconsistent manual work by automatically performing a range of laborious image analysis tasks, in a fraction of time with unprecedented accuracy and consistency. The productivity leap is enabled by our deep learning AI software, implemented on a cloud platform, and developed specifically for pathology. The platform has been built by Aiforia Technologies Oy, a Finnish SME, bringing together a team of experts in medicine, business, and software development. The award-winning Aiforia® Cloud is already used by more than 50 organisations for research purposes. With the AiforCancerDx project, the platform will be introduced to clinical use. We will build the world’s first ready-made deep learning algorithms for automated cancer diagnostics. The project allows Aiforia Technologies to remain at the forefront of the digital revolution of pathology and capture a significant share of the global market expected to grow to €900 million by 2020.
Amphiphilic Peptoids as General Tool for Membrane Proteins Stabilization and Crystallization (Pro-Membrane)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-01
End date: 2017-04-30
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 2
Project status: CLOSED

“Pro-Membrane” is an extensive project which has been structured to face multiple tasks of different levels of innovation and risk. In its longest-term and most ambitious goal, Pro-Membrane, aims to face the still not solved challenge of stabilize and crystallize Membrane-Proteins (MPs). This study will use, as innovative tool, well-ordered and disordered functionalizable amphiphilic peptoids for structural determinations. Peptoids could indeed succeed where other classes of molecules previously failed, answering to the pressing need of a new method able to establish the specific interactions to stabilize and crystallize each MP. Their peculiar nature helps them to easily cross the membrane and their modular synthesis give access to an infinite combination of molecules. Despite their interest, a systematic and comparative study of their physical properties and self-assembly capacity was never done before. The multidisciplinarity of this work, between Organic Chemistry, Biophysics, and Structural Biology will be achieved through a strict collaboration between all the participants. Training through research and implementation activities have been planned to maximize the candidate’s profile in order to support his career perspectives.

Keywords: membrane proteins,amphiphilic peptoids,conformational analysis,thermodynamics of hydrophobic interactions,detergents and surfactants,structural studies
Advanced Analytics for Trip Origin-Destination Matrices (TripOD)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Spain
Call: Small business innovation research for Transport (H2020-SMEINST-1-2014, 2014)
Start date: 2014-09-01
End date: 2015-02-28
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The planning and management of transport systems requires accurate, reliable and updated travel demand information, including travellers’ socio-economic profile, origin and destination of the trips, trip purpose, transport modes and route choice. Traditional data collection methods, such as household travel surveys, are expensive and require months or even years to complete. TripOD is an innovative solution developed by Nommon that mines and analyses a variety of ICT-based data sources (e.g., mobile phone records, smart cards), alone or in combination with traditional data (e.g., census, traffic counts), to provide frequently updated and rich demographic and travel demand information in a fraction of the time and cost required by traditional methods. The targeted users are those stakeholders in need of travel demand data, including public authorities and agencies in charge of transport planning and management, public and private transport operators and service providers (e.g., toll road concessionaires), consultants and researchers. Altogether, these users constitute a market of significant size, which is expected to grow continuously along the coming decades due to the increasing awareness about the importance of sustainable and efficient transport systems and the cost-efficiency of the TripOD solution, which makes it affordable for public bodies and companies of any size. The overall goal of the feasibility study is to assess the technological and economic viability of the proposed concept and elaborate a detailed business plan. The specific objectives are: - to evaluate the technical feasibility of the solution in operational conditions; - to provide an in-depth analysis of the market at worldwide level, including users and their needs, competitors and entry barriers, data providers, stakeholders and potential alliances; - to evaluate financial feasibility; - to design a strategy to protect intellectual property rights; - to identify risks and opportunities.

Keywords: travel demand information,transport planning,transport operators,big data,data mining,data fusion,spatio temporal data,informed decision making,cost savings
Radio technologies for 5G using advanced photonic infrastructure for dense user environments (RAPID)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Countries involved: Germany,Israel,Germany,Poland,United Kingdom
Call: Access networks for densely located users (H2020-EUJ-2014, 2014)
Start date: 2014-10-01
End date: 2017-09-30
Duration (months): 36.0
Total project cost (EUR): 1549755.0
EU funding (EUR): 1549755.0
Participants: 5
Project status: CLOSED

In RAPID, we propose to use a centralized radio access (C-RAN) architecture to support high-capacity heterogeneous (3g, 4G and 60 GHz) radio access technologies through low-cost, but ultra-high-bandwidth photonic techniques for the fibre distribution. To meet the requirement to transport the high-frequency (and wide-bandwidth) wireless signals at low-cost, a novel coherent radio-over-fiber (CRoF) scheme is proposed in RAPID. Furthermore, for the mobile receiver, novel extremely low-cost (<10€) integrated transceivers will be developed based upon a SiGe technology. The radio resource management of the heterogeneous network using the developed mm-wave and photonic technologies together with legacy 3G/4G wireless will be demonstrated in RAPID and the developed hardware will be tested in life-cycle assessments within different real life networks scenarios including a public stadium, an operators fiber-optic and wireless network, as well as in train, airport scenarios.

Keywords: high capacity wireless network,heterogeneous networks,centric wireless network architecture,coherent radio over fiber
Low Power and Fault Tolerant Cache Memory Design through a Combination of Hardware and Software Approaches (PALMERA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Norway
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-05-01
End date: 2022-01-15
Duration (months): 24.0
Total project cost (EUR): 208400.4
EU funding (EUR): 208400.4
Participants: 1
Project status: CLOSED

PALMERA will address the low power and fault tolerant cache memory design bottleneck through a combination of hardware and software approaches. The proposal has two research directions: (1) Develop a cache memory hardware equipped with novel circuit designs to keep the reliability during voltage scaling. (2) Leverage the software application level to manage energy consumption. A methodology will be developed that enables the programmer to identify non-critical data structures and program phases that are not memory-bound. Through a system scenario design methodology, this information is used to manage the settings of the underlying novel hardware to increase error resilience and save energy. The focus is on memories implemented for embedded systems in areas such as medical imaging and space applications, typically having strict requirements for both energy consumption and reliability. These types of applications are increasingly becoming multitasked and dynamic; hence, data intensive and fluctuating with respect to resource requirements. Available static analysis and worst-case design margins cannot any longer meet the power and reliability constraints. Compared to previous techniques that typically focus on either hardware or software when optimizing for both energy and reliability, PALMERA adopts a multidisciplinary holistic approach where hardware and software levels of the system are combined. Working towards these challenging project goals not only moves the research front forward, but also gives the Experienced Researcher excellent opportunity to develop her skills and career potential. The combination of PALMERA research, with high quality training at the host institution and during secondment, strengthens her knowledge and experience and provides the best opportunity for her to gain a position as a senior researcher in industry or academia. The goal is for PALMERA to be an enabler for the next step, being a proposal for a European Research Council grant.

Keywords: low power circuit and system design,high performance,fault tolerance,resilience,cache memory design,vlsi,embedded systems,system scenario technique,software engineering
Dissecting Multivalent Viral Receptor-carbohydrate Interactions Using Polyvalent Multifunctional Glycan-Quantum Dot (DC-SIGN-MFN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-07-13
End date: 2020-07-22
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Multivalent lectin-sugar interactions play a key role in facilitating viral infections, affecting hundreds of millions people worldwide. Understanding the structural mechanisms is key to be able to design glycoconjugates that can block such interactions, thereby preventing infection. However, research advances have been hampered by inability of current methods to reveal key structural information of some important cell surface lectins. For example, despite 17 years of extensive research, the structure of two vitally important tetrameric lectins, DC-SIGN and DC-SIGNR, remain unknown. These lectins bind to virus surface multiple glycans and enhance many viral infections (e.g. HIV, HCV and Ebola). This fellowship will address this challenge by developing a novel multimodal readout strategy (e.g. FRET, TEM and particle size analysis) using compact polyvalent glycan-quantum dots (QD) to fully exploit multivalency and QD’s unique properties. By tuning QD surface glycan structure, valency, inter-glycan spacing and flexibility, we will create a perfect spatial & orientation match to those of glycan-binding-domains (CRDs) in DC-SIGN/R, leading to greatly enhanced binding affinity. By studying QD-glycan binding with DC-SIGN/R, we will reveal key structural data (e.g. CRD orientation, distance, binding mode) in DC-SIGN/R. We will verify the binding data with native receptors on cell surfaces, correlate receptor binding affinity with virus inhibition potency, and study their immune cell activation. This research is extremely timely and important because it will, 1) address the capability gap of current methods; 2) reveal key structural information of CRD spatial arrangement in DC-SIGN/R; 3) reveal how ligand multivalency & affinity control intracellular trafficking and modulate dendritic cell response. These are important not only to fundamental structural biology, lectin biochemistry, chemistry, and nanotechnology, but also to develop novel potent anti-viral reagents.

Keywords: quantum dot,fret,glycoconjugate,multivalent interaction,lectin,multimodal readout,multi functional nanoparticle,viral infection and inhibition,binding affinity
EEN InnoSupp BG-3 (EEN InnoSupp BG-3)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Bulgaria,Bulgaria,Bulgaria,Bulgaria,Bulgaria,Bulgaria,Bulgaria,Bulgaria
Call: EEN H2020 SGA3 (H2020-EEN-SGA3-2018, 2018)
Start date: 2019-01-01
End date: 2019-12-31
Duration (months): 12.0
Total project cost (EUR): 45007.5
EU funding (EUR): 45007.5
Participants: 12
Project status: CLOSED

The main objective of this project is to contribute to the implementation of the European policies in the field of innovation management capacity building in SMEs and their implementation in Bulgaria, resulting in effective and efficient investments in novelties leading to growth and quality jobs. As a major tool for improving global competitiveness of European companies, implementation of novelties in products, processes and society needs specially devoted attention and resources. This project will contribute to the better filtering and acceleration of innovation processes in Bulgarian SMEs, thus supporting growth and jobs. Supported companies are supposed to be better prepared for using Access to Finance instruments and attract investments in innovation.

Keywords: sme support,innovation,innovation management,access to finance,business acceleration,investment
The History of Human Freedom and Dignity in Western Civilization (HHFDWC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Germany,Italy,Germany,Hungary,Palestine, State of,Czechia,United Kingdom,United Kingdom,United Kingdom,United Kingdom,Denmark
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2015, 2015)
Start date: 2016-01-01
End date: 2021-07-31
Duration (months): 67.0
Total project cost (EUR): 3651149.88
EU funding (EUR): 3651149.88
Participants: 16
Project status: CLOSED

The ETN has two aims: to a) train ESRs; b) investigate the The History of Human Freedom and Dignity in Western Civilization. a) The ETN will establish an innovative training programme which allows the ESRs to obtain specialist knowledge of a specific research topic and to obtain transferable skills enabling the students to apply their knowledge in non-academic institutions, e.g. dealing with social welfare, human resources, or legal /political institutes. The training program includes acquiring transferable skills via courses and via secondments in non-academic partner organisations. b) The thesis of the research is that the concept of the ideal modern Western European human being has its roots far back in the history of philosophy and theology. This ideal human being has the right to think, believe, and express itself freely about all matters without fearing retribution, and to be treated as an autonomous and dignified individual. But such a conception is not shared by all – and never was. Its long history has been formed through a continuous battle between two theological and philosophical traditions going back to Origen from Alexandria and Augustine of Hippo respectively. Origen saw humans as free, valuable and dignified beings, while Augustine saw them as predestined, sinful and bound to servitude. The network will investigate the reception and use of Origen’s ideas in order to provide a comprehensive and historically based understanding of these fundamental values, their origins, development and the fights they have gone through. Only then can we argue for their continued place in modern society. Such a project is highly relevant today, since the modern conception of humans is a fundamental pillar of Western democracies which is under pressure from both political and fundamentalist religious groups that question the societal structures building on ideas of humans’ freedom and dignity, and by global crises and structures that limit the individual’s autonomy.

Keywords: human freedom,human dignity,religious fundamentalism,origen of alexandria,augustine of hippo,theology,philosophy,reception history,enlightenment,network and reception theory
Disruptive Modes and Materials of Energy Storage (MoMa-STOR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Germany,France,France
Call: ERC Synergy Grant (ERC-2020-SyG, 2020)
Start date: 2021-01-01
End date: 2026-12-31
Duration (months): 72.0
Total project cost (EUR): 5748695.99
EU funding (EUR): 5748695.99
Participants: 3
Project status: SIGNED

Sustainable energy generation by water, wind, and solar has reached in the EU a mature and economic state, but further growth to tackle the climate crisis has faltered because more economic, scalable and sustainable energy storage concepts are missing. The groups of both PIs have a proven track record in this area but, interestingly they were able just recently to perform first experiments indicating big potential gains in performance. The Simon group identified a specific ion organization in nanoporous carbon electrodes leading to enhanced capacity. He also evidenced fast, new pseudocapacitive redox contribution in metal carbides of still unclear origin. The Antonietti group could not only build from oxidation stable noble carbons a 6.5 Volt supercapacitor, but also show that in those new device major storage peaks come from solvent structure changes. In another work, massive sub-potential deposition of Na-metal was observed is the Schottky transition layers of hybrid materials, thus making sodium batteries potentially save and efficient. The general aim of MoMa-STOR is to address such fundamentally new, non-classical and non-technically covered modes of energy storage and to develop the related materials base for them, to design the next generation of energy storage devices. These new modes include a) energy storage by desolvation and matrix change, b) reversible high energy bulk structure transition, and c) metal-metal and metal-semiconductor heterojunction interface effects. New modes will be carefully analysed with advanced electrochemical techniques, including quartz crystal microbalance, differential electrochemical mass spectroscopy, combined with in situ X-ray and Raman spectroscopy for instance, to gain a precise physico-chemical picture of the operation principles. In operando high resolution electron microscopy and EELS will complete the molecular understanding of the processes.

Keywords: electron storage,low dimensional nanomaterials,supercapacitor,ionic liquid,in operando analytics
Collaborative Planning in China: Authoritarian Institutions, New Media, Power Relations, and Public Spheres (CoChina)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2021-02-01
End date: 2026-01-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Collaborative planning has become an effective means to address conflicts of interest in urban renewal and environmental management in China. However, the egalitarian principles that ground collaborative planning theory call into question its validity in China. The theory emphasizes consensus building in which various stakeholders come together for dialogue to address controversial issues. It rests on three assumptions: democratic institutions, neutral power and communicative rationality. These assumptions, which are often debated in the Western context, should clearly be questioned in the Chinese context, due to authoritarian institutions and the challenging nature of power relations. Therefore, the aim of my project is to examine the practices of collaborative planning in China and identify the challenges to the assumptions of the theory. I will develop three novel tracks for examination and reconceptualization. The first will analyze how Chinese political and planning systems, social capital and culture affect the interactive processes. The second will apply network theory and social network analysis to analyze various types of power relations between government, planners, civil society and citizens. The third will identify various forms of online public spheres and how they interact with offline public spheres to affect communicative and agonistic approaches to collaborative planning. The research will employ an innovative mixed methods approach combining critical discourse analysis, data mining, computer-assisted content analysis, and social network analysis to research a wide range of case studies. My project will lead to a new understanding of collaborative planning in China, and a reconceptualization of the collaborative planning theory to make it suitable for authoritarian contexts.

Keywords: collaborative planning,authoritarian institutions,new media,power relations,public spheres,china