Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
AgriLoop: Pushing the frontier of circular agriculture by converting residues into novel economic, social and environmental opportunities (AgriLoop)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Circular economy and bioeconomy sectors
Action type: Research and Innovation actions
Countries involved: France,Netherlands,Portugal,Italy,Spain,Belgium,Croatia,Switzerland,China,Denmark,United Kingdom,Germany
Call: EU-China international cooperation on unlocking the potential of agricultural residues and wastes for circular and sustainable bio-based solutions (HORIZON-CL6-2022-CIRCBIO-01, 2022)
Start date: 2022-12-01
End date: 2026-11-30
Duration (months): 48.0
Total project cost (EUR): 7825297.5
EU funding (EUR): 7825297.0
Participants: 38
Project status: SIGNED

The 35 partners (half academic/private) of the International AgriLoop consortium aim to extend the agricultural production value of two major players of the global bioeconomy: EU and China, by eco-efficiently upgrading underexploited residues into a portfolio of high added-value bio-products able to generate new bio-based markets or to compete with, and gain market share of, oil- and food crops- based equivalents. AgriLoop will develop safe-and-sustainable-by-design (SSbD) bioconversion processes integrated in a cascading biorefinery approach to convert a range of agri-residues (from e.g. tomato, soy, straw, potato, brewery, oil, winery and livestock sectors) into plant and microbial proteins, polyesters and other bio-based chemicals to be used for food, feed, health and materials applications, especially by the farming sector. AgriLoop scientific and technical objectives are to i) improve the recovery of highly functional native molecules from primary and secondary residues and to tailor bioconversion schemes toward microbial proteins and polyesters, for overcoming in a balanced way the limitations related to feedstock complexity, processes eco-efficiency and end-products performances, and in parallel ii) anticipate the complex circularities of such biorefinery to comply with safe and sustainable requirements, guide scientific and technological advances of AgriLoop cascading processes toward end-products tailored to the just necessary (frugal design) and fast track their further adoption as demonstrated in upscaling selected biorefineries schemes. By strengthening EU-CN cooperation, informing SSbD guidance and opening up new avenues for flexible agri-based value chains, AgriLoop will increase resources efficiency through reduced discharges of agricultural residues, while taking share of the highly dynamic worldwide markets of alternative proteins and biochemicals (incl. biopolymers) and reducing the cost of agriculture and food system on our environment and health.

Keywords: agri residues valorisation,cascading biorefineries,safe and sustainable by design,bioproducts for farming sector
Cavity-Integrated Electro-Optics: Measuring, Converting and Manipulating Microwaves with Light (CIELO)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Research and Innovation actions
Countries involved: Austria,Czechia
Call: Hop-on facility (HORIZON-WIDERA-2025-03, 2025)
Duration (months): 36.0
Total project cost (EUR): 224315.0
EU funding (EUR): 224315.0
Participants: 2
Project status: CLOSED

Electro-optic technologies have emerged as one of the leading platforms in both classical and quantum communication landscapes. The advent of circuit quantum electrodynamics (cQED) based on low-loss Josephson junction circuits has led to spectacular scientific breakthroughs in quantum science and technology. In recent years, these breakthroughs have been translated into commercial quantum computing efforts worldwide, targeting a market with an estimated value of 1 billion Euro. Despite these achievements, there are fundamental limitations to quantum technologies based solely on microwaves. Operating in a millikelvin environment, the space required for wiring and electronics as well as the associated heat loads are barriers for scaling up the quantum processors to the size needed to address societal challenges. Electro-optic interconnects capable of coherently distributing and transferring quantum information from superconducting processors to a room temperature environment would address this challenge. Such devices would enable quantum processors to be scaled up in a modular fashion, which will be key to realizing complex and capable quantum machines that remain controllable and error-correctable. Moreover, these microwave-optical interfaces would also form the basis for efficient laser-driven microwave technologies relevant to sensing applications, such as microwave astronomy or robust and low-noise microwave amplification. In CIELO, we aim to lay the foundation for laser-based manipulation of microwave fields using cavity electro-optics, enabling amplification, quantum-limited optical detection, interconversion, qubit readout, laser cooling and masing, in stark contrast to the commonly used electrical techniques. We will leverage a combination of unique expertise in integrated photonics, advanced materials, and superconducting qubits to realize cavity electro-optic devices operating in the quantum regime.

Keywords: microwaves,electro optic modulation,pockels effect,cryogenics,superconducting qubits,quantum computing,maser,quantum entanglement,standard quantum limit
Novel design of offshore wind farms by employing high-fidelity computations to mitigate their acoustic impact on marine life (WhaleNoise)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Australia,United Kingdom
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-05-15
End date: 2027-05-14
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 3
Project status: CLOSED

WhaleNoise emerges as a timely and essential initiative, born from a dual sense of purpose driven by two pressing concerns. Firstly, with the urgent need to achieve ambitious targets in clean energy generation, the European Union set forth its 2020 Strategy on Offshore Renewable Energy, aiming for a remarkable 300 GW of offshore wind capacity. In response to this accelerated timeline, the development of offshore wind technology has seen rapid advancements to meet the escalating demand for clean energy. Secondly, over the past 20 years, the world has witnessed a remarkable surge in awareness regarding acoustic pollution in the oceans. This awareness is evident through the increasing number of scientific publications on the subject and the implementation of new regulations aimed at protecting the hearing thresholds of marine animals. Two commonly cited problems with respect to marine renewable devices are collision risk and noise impact. The former is concerned with marine life being unable to determine the locations of devices, also known as the masking problem, and may be alleviated by introducing specially designed warning devices. The latter regards the damaging effect of acoustics generated by the turbine on marine animals (e.g., noise masking communication between individuals) and can be reduced only via a redesign of energy farms. WhaleNoise aligns with these environmental imperatives, as it addresses both challenges in a synergistic manner. Its core mission is to understand and predict the acoustic emissions from offshore wind farms (fixed and floating), seeking to evaluate their detrimental impact on marine life. By striking this delicate balance between clean energy generation and ecological conservation, WhaleNoise promises to contribute significantly to a sustainable and harmonious future for our oceans and the life they nurture.

Keywords: offshore wind turbines,computational fluid dynamics,aeroacoustics,high order methods,high performance computing
Dynamic Resilience Assessment Method including combined Business Continuity Management and Cyber Threat Intelligence solution for Critical Sectors (DYNAMO)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Increased Cybersecurity
Action type: Research and Innovation actions
Countries involved: Germany,Austria,Greece,Portugal,Finland,Belgium,Ireland,Bulgaria,Italy,France
Call: Dynamic business continuity and recovery methodologies based on models and prediction for multi-level Cybersecurity (HORIZON-CL3-2021-CS-01, 2021)
Start date: 2022-10-01
End date: 2025-12-31
Duration (months): 39.0
Total project cost (EUR): 4998987.51
EU funding (EUR): 4998987.51
Participants: 18
Project status: SIGNED

The scope of DYNAMO is to combine the two fields of business continuity management (BCM) and cyber threat intelligence (CTI) to generate a situational awareness picture for decision support across all stages of the resilience cycle (prepare, prevent, protect, response, recover). Professionals of different backgrounds will work together with end-users to develop, refine and combine selected tools into a single platform. In alignment to end-user needs, human factors, high ethical standards and societal impacts, DYNAMO includes the following goals: Resilience assessment as basis for BCM - An assessment with different levels of detail offers with varying existent data a fast or detailed evaluation of the investigated sector and helps to identify critical processes. - End-user data will be integrated to measure determined performance targets. With respect to the functional description, AI-based approaches will be used for a deeper understanding and potential self-learning of the interconnected process. - The results generate knowledge concerning susceptibility and vulnerability of the investigated sector. - The solutions support the BCM with respect to the five resilience phases. Leveraging CTI - CTI will be improved with respect to existing solutions (H2020 ECHO, PANACEA). - The H2020 Early Warning System (EWS) will be extended and integrated. A Malware Information Sharing Platform (MISP) will be used to raise the situational awareness between different security actors. - The CTI approach deliver data that will be integrated into the resilience and BCM approach. The use of AI will support the development. Solutions will be integrated with the Cyber Knowledge Graph to visualize the analysis of threat intelligence. The DYNAMO platform will be able to collect organization’s skills data, elaborate and create custom tailored organisational training to improve organisational resilience which will be demonstrated within three different (cross-)sectoral use-cases.

Keywords: combined cti and bcm platform situational awareness picture increase coping capacity resilience enhancement methodology
Welcoming highly-talented international post-docs in Brittany (BIENVENUE PLUS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: France
Call: MSCA COFUND 2024 (HORIZON-MSCA-2024-COFUND-01, 2024)
Start date: 2025-11-01
End date: 2030-10-31
Duration (months): 60.0
Total project cost (EUR): 8460000.0
EU funding (EUR): 8460000.0
Participants: 2
Project status: SIGNED

Offering the best conditions to postdoctoral fellows for their bottom-up, self-built research projects, within a consortium that gathers all the research units based in Brittany, with training and career development aimed at internationalisation, intersectoriality and interdisciplinarity, and a unique 6-month placement opportunity: such are the ingredients of the BIENVENÜE+ project, that aims at strengthening regional excellence through the recruitment of 75 high-level international postdoctoral fellows (24-month fellowships). BIENVENÜE+ represents a central pillar for the better articulation of funding opportunities for international post-doc fellows at regional level. It ambitions to promote the implantation and integration of new skills in Brittany and to develop excellence and international visibility of regional research in contribution to Région Bretagne Research and innovation smart specialisation strategy (RIS3). With this approach, BIENVENÜE+ is open to any discipline. BIENVENÜE+ is strongly innovation-oriented and, as such, it offers, in addition to non-academic secondments, an optional unique additional 6-month placement in a non-academic institution, at the end of the 24-month fellowship. In terms of training plan, BIENVENÜE+ includes arising key issues for researchers such as Open Science, science outreach and environmental aspects of research. The BIENVENÜE+ consortium, coordinated by Région Bretagne, is composed of 20 complementary Host Institutions (HI). This large consortium, embracing the entire regional R&I academic community, widens research and career development opportunities for the fellows relying, among others, on the participation in 6 European Universities Alliances.

Keywords: regional development smart specialisation strategy self built and innovative research and training projects otm r career development non academic placement
Impact of climate change on zoonotic vector-borne diseases and their potential transmission increase and introduction risk: An innovative approach with a selected disease model (FascioClim)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain,Switzerland
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-11-01
End date: 2025-08-31
Duration (months): 34.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 2
Project status: CLOSED

Vector-borne diseases (VBDs) pose a major threat to the health of societies around the world, with more than 80% of the global population at risk of at least one major VBD. VBDs are particularly susceptible to the effects of climate change, which will affect the distribution of vectors, the spatial and temporal patterns of the diseases vectors transmit, as well as the efficiency and intensity with which vectors transmit pathogens. A climate-driven phenomenon of outbreaks of VBDs, many of them zoonotic, is occurring worldwide, and Europe is not the exception. In this complex scenario, as climate change accelerates, globalisation spreads vectors and pathogens, and other human-caused disturbances increase, it is urgent to assess and predict impacts on disease transmission. We aim to assess the response of zoonotic VBDs to climate change and the potential threat it entails to Europe by using fascioliasis as a selected model. Fascioliasis, a complex zoonotic snail-borne disease, represents an ideal model as it has a low reservoir specificity, a high number of snail host species, and has already evinced being influenced by climate and global changes. We propose an integrative modelling framework for fascioliasis transmission: we will apply some innovative ideas in the field of ecological niche modelling combined with the use of climatic forecast indices, to identify the overlap between niches of fasciolids and snail hosts, and determine the area under risk of transmission. In addition, we will provide open-source tools accessible to the health sector. We expect this innovative ensemble of modelling approaches could be applied for assessing climate change impact on other zoonotic VBDs (in particular schistosomiasis, other snail-borne disease, but also mosquito- and tick-borne diseases, such as West Nile fever, Dengue, Zika, and Crimean-Congo haemorrhagic fever), in order to provide tools to guide interventions aimed to reduce and/or mitigate the disease burden in Europe.

Keywords: vector borne diseases disease biogeography climate change zoonosis fascioliasis
Gene Therapy for treatment of rare inherited Arrhythmogenic Cardiomyopathy (GEREMY)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: Netherlands,Germany,Finland,Belgium,United Kingdom,Portugal
Call: Development of new effective therapies for rare diseases (HORIZON-HLTH-2022-DISEASE-06-two-stage, 2022)
Start date: 2023-05-01
End date: 2027-04-30
Duration (months): 48.0
Total project cost (EUR): 7774103.75
EU funding (EUR): 7774103.75
Participants: 11
Project status: SIGNED

Development of a cure for rare cardiac diseases is a risky, costly and time-consuming process, which is hampered by insufficient insight into pathophysiological mechanisms of the diseases and lack of relevant disease models. The GEREMY consortium proposes to overcome this challenge by developing a gene therapy (GT) for inherited arrhythmogenic cardiomyopathy (ACM), by targeting the disease-causing PLN (non-desmosomes) and PKP2 (cardiac desmosomes) mutations. The GEREMY consortium will apply a unique parallel approach and investigate various promising GT approaches (oligonucleotide chemistries, gene editing and gene delivery). Also, the consortium will engineer disease models for proper assessment of therapeutic interventions and aims to provide in vitro & in vivo preclinical proof-of-concept for the GT. A significant benefit compared to current technologies is that the GT has the potential to be a curative treatment for rare cardiac diseases. Based on previous successes, GEREMY will target PLN & PKP2 as a roadmap of the technology. Restoring the primary defect in the PLN & PKP2 genes that cause the disease will lead to preserving or even restoring myocardial contractility. Through this approach, GEREMY will work towards a curative treatment of inherited ACM and likely other cardiomyopathies, which significantly reduces the healthcare burden. The project’s experts in preclinical research and cardiac genetics will deliver preclinical efficacy and safety data for the mutation correction. The partners with regulatory and clinical trial expertise (EXOM, EUF, NLHI) will prepare for immediate start of clinical trials upon project completion, and apply for orphan drug designation. EUPATI, a patient organisation and KUL ethics partner will ensure that the project is continuously aligned with patient needs and ethical perspectives. The whole consortium will contribute to communicate an disseminate the results to ensure maximum exploitation of this breakthrough technology.

Keywords: cardiomyopathies,pln,pkp2,oligonucleotide chemistries,gene editing and gene delivery,patient engagement
Atomic-Scale Tailored Materials for Electrochemical Methane Activation and Production of Valuable Chemicals (ATOMISTIC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Spain
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 1999774.0
EU funding (EUR): 1999774.0
Participants: 1
Project status: SIGNED

Electrochemical methane activation and direct conversion to methanol is highly attractive – a dream reaction that would convert a greenhouse gas into a valuable liquid fuel in a dream device, on-site, and powered by renewable electricity. However, sustainable C-H activation and direct methane to methanol conversion at ambient conditions remain as great fundamental challenges. My aim with ATOMISTIC is: (i) to develop new methods for electrochemical methane activation and partial oxidation, (ii) to control the structure of the electrochemical interface and the catalytically active site, in order to tune selectivity for the synthesis of valuable fuels and chemicals (such as methanol) from methane, and dimethyl carbonate from methanol. I will use 3 main strategies: - To establish the ideal structures and electrolytes, using well-defined tailored materials that enable methane activation by its direct adsorption on the electrode material. - To realise advanced materials that enable the indirect electrochemical activation of methane through the generation of solution phase radicals. - To tailor the active site at the atomic level for selective methane to methanol and methanol to dimethyl carbonate oxidation reactions on functional materials. I will elucidate the design principles and unveil the structure-reactivity-selectivity relations and the molecular mechanisms of these reactions as well as the atomic-scale structure of the catalyst materials. I will achieve these ambitious goals by leveraging my work combining the insight from model studies with experiments under realistic conditions to discover new materials. I will combine electrochemical methods, electrochemical scanning probe microscopy, in situ optical spectroscopy, online mass spectrometry and operando synchrotron-based x-ray techniques. The success of ATOMISTIC will result in significant breakthroughs in the fields of chemistry and catalysis, opening up new sustainable ways to produce valuable chemicals.

Keywords: functional materials methane small molecule activation methane activation surface modifiers structure sensitivity advanced materials direct methane oxidation,electrochemistry catalysis surface chemistry electrocatalysis energy materials electrosynthesis active site engineering electrolyte effects surface properties relations nanomaterials engineering radical reactions value added chemicals