Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Collective Learning Data Lab (LearnData)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Coordination and support actions
Countries involved: Hungary
Call: ERA Chairs (HORIZON-WIDERA-2022-TALENTS-01, 2022)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2493750.0
EU funding (EUR): 2493750.0
Participants: 1
Project status: SIGNED

Data fuels the digital economy. This demands training new generations of experts on how data is collected, stored, processed, and analyzed. Corvinus University of Budapest (CUB) is working to become a leading business and economics university in Central and Eastern Europe by combining data science skills with expert knowledge in business and economics. The support of the ERA Chair Program will reinforce institutional reforms at CUB designed to transform it into a hub of research and teaching excellence in applied data science, expanding the international attractiveness of CUB through cutting-edge training programs and innovative industry collaborations. We will establish the new Collective Learning Data Lab (CLDL) with the leadership of Professor César Hidalgo, a world-class researcher in data science, economic geography, and network science. By leveraging synergies with outstanding research groups at CUB, the Collective Learning Data Lab is projected to grow into a leading Center for Data and Network Science. This will create an environment for the university to learn key methods and publish in top interdisciplinary, economics, business, and social science journals. The Lab will be a flagship project involving students in experiential data-driven work. Lab members will engage in advising PhD programs and in developing BA specializations and Master programs in social- and business-oriented data science. The Lab will widen CUB’s industry collaborations with data-oriented companies and public policy use cases. Building on Budapest’s strong tradition in network science, CLDL will impact Hungary and Central and Eastern Europe by equipping society with the skills needed to undertake new challenges.

Keywords: data science,economic geography,collective learning,urban data science,machine learning,complex systems
Dissecting and targeting malignant cell-fibroblast crosstalk driving cachexia in pancreatic cancer (CAFinCAC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 1
Project status: SIGNED

Cancer-associated “cachexia” is a debilitating condition that causes patients to lose weight and muscle, which limits treatment options and worsens survival. Often patients diagnosed with pancreatic cancer, a lethal and increasingly common malignancy, are affected by cachexia. Little is known about cachexia and no therapies exist. It is thus important to identify causes of cachexia to develop treatments. Pancreatic tumours contain abundant non-cancerous cells, called "fibroblasts", that promote cancer progression. My host laboratory found various types of fibroblasts that promote pancreatic cancer in different ways. Moreover, they found that genetic mutations of the cancer cells change the fibroblasts. While lots is known about how fibroblasts promote cancer, we know little about how they affect cachexia. My research objective aims to identify features of pancreatic cancer fibroblasts that promote cachexia to guide the development of therapies. I first aim to determine how genetic mutations that alter the composition of pancreatic cancer fibroblasts affect cachexia (Objective 1). I will then test how pancreatic cancer-associated cachexia is affected when fibroblast composition is altered using mouse models that were recently engineered by my host laboratory (Objective 2). This work will highlight candidate therapeutic targets of cachexia. Importantly, cachexia also affects patients with other cancers and diseases, and fibroblasts in these conditions share features with pancreatic cancer fibroblasts. Thus, my project could have a broad impact. My research background in pancreatic cancer and the models of the host laboratory will guarantee the successful completion of this project. Working with the host supervisor, a world-leading expert on pancreatic cancer fibroblasts, along with the training program outlined, will have a long-lasting impact on my scientific career and will help me transition into an independent position as a cachexia-focused researcher.

Keywords: pancreatic cancer,cancer associated cachexia,cancer associated fibroblasts,tumour microenvironment
EXOsome analysis business for inclusive innovation ecosystem in EU (EXO4EU)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Netherlands
Call: Women TechEU (HORIZON-EIE-2021-SCALEUP-01, 2021)
Start date: 2022-06-01
End date: 2023-05-31
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

EXIT071 (EXosome Isolation Tool) is a Leiden based startup developing pioneering technology for the analysis of novel biomarkers exosomes. We are a young yet experienced startup with great motivation and ambition to bring a very much needed technological solution to a highly potential exosomes market. This funding opportuning Women TechEU from Horizon Europe comes at the perfect time for EXIT071. The technology is already proven to perform, plan, partners and finances for technological development are secured and the team is coming together. In this project EXO4EU – EXOsome analysis business for inclusive innovation ecosystem in EU, we propose activities for in-depth makeover of our business plan and strategy enhancement. The networking opportunities offered by InvestEU and the Enterprise Europe Network are very appealing for our early integration into the European ecosystem of innovation. Being mentored and coached under the Women Leadership Programme will have a bespoken value for the passionate founder and quickly learning CEO, Dr. Yuliya Shakalisava, who is making a challenging yet exciting career transitioning from research to business.

Keywords: microfluidics,exosomes,extracellular vesilces,therapeutics,diagnostics
Strengthening law enforcement with advanced IoT forensic tools and enriched investigation schemes, realised by a Software Defined Network Security-as-a-Service architecture (SALUS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Fighting Crime and Terrorism
Action type: Research and Innovation actions
Countries involved: Greece,Belgium,Portugal,United Kingdom,Cyprus,Bulgaria,France,Germany,Luxembourg,Finland,Spain,Ukraine
Call: Mitigating new threats and adapting investigation strategies in the era of Internet of Things (HORIZON-CL3-2024-FCT-01, 2024)
Start date: 2025-11-01
End date: 2028-10-31
Duration (months): 36.0
Total project cost (EUR): 4999077.5
EU funding (EUR): 4999077.5
Participants: 19
Project status: SIGNED

SALUS addresses the growing security challenges of IoT systems by providing law enforcement with (i) new forensic investigation schemes and policies, and (ii) advanced IoT forensic tools for threat detection, evidence collection, and cross-agency collaboration, all while ensuring compliance with EU legal and ethical frameworks. To implement this, the project combines a novel Digital-Twin (DT) infrastructure for proactive threat simulation, a secure Software Defined Network-enabled IoT architecture (SDaaSS) acting as the backbone of the DT for dynamic policy enforcement, and AI-powered forensic capabilities for real-time IoT device detection, lawful evidence interception, and blockchain-based chain of custody. Validated through five diverse pilot use cases in collaboration with five (5) police authorities and two (2) critical infrastructure providers (hospitals and nuclear power plants), SALUS bridges technology and operational needs to enhance security in critical infrastructures and IoT ecosystems. The above technological developments will be closely accompanied by activities concerning: i) incorporation of legal and ethical aspects, including fundamental rights, privacy, personal data, etc, ii) integration of operational aspects, alignment with relevant EU cybersecurity policies, analysis of modus operandi, lawful evidence exploitation, and delivery of policy recommendations for tackling new and emerging forms of IoT-related crime, all aimed at improving police authorities’ understanding, iii) development of multi-dimensional, comprehensive practitioner training activities and joint exercises, tailored to the organization of operational-level hackathon activities, iv) Development of investigation, technological and security standards, and v) Establishment of a synergistic ecosystem among related national and EU-funded projects, as well as stakeholders from the law enforcement community.

Keywords: investigation schemes iot digital forensic toolkit software defined network as a security service digital twin ai empowered simulation services law enforcement agencies,training hackathons
Development of indicators & econometric analysis on R&I performance (INNOVA MEASURE V)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Other topics
Destination: Other destinations
Action type: Coordination and support actions
Countries involved: Belgium
Call: Development of indicators & econometric analysis on R&I performance (HORIZON-HORIZONTAL-2021-INDICATORS-IBA, 2021)
Start date: 2021-11-01
End date: 2023-04-30
Duration (months): 18.0
Total project cost (EUR): 404983.75
EU funding (EUR): 404983.75
Participants: 1
Project status: CLOSED

This project continues the research activity carried out by the JRC in support of the work on better evidence for policy-making by the Directorate-General for Research & Innovation (R&I). It focuses on three interrelated research streams. The first research line consists in the development, refinement and update of the methodologies concerning composite indicators and dashboards measuring R&I performance of EU Member States (MSs) and selected benchmark countries, more specifically, the Innovation Output Indicator (IOI) and the People, Planet and Prosperity (3P) dashboards. The second research line concerns the green and digital technologies in the EU and the knowledge base needed for their development, and includes a description of recent technological trajectories and an analysis of the role of innovative foreign direct investments flows to the establishment of the related knowledge base. The third research line is about the complex relationships between digital technologies on the one side and the social, economic and environmental domains of sustainable development on the other one. Using the lens of scientific knowledge through scientific publications, the research entails first the benchmarking of EU MSs performance in the production of pertinent scientific knowledge, and second the assessment of the contribution of advanced digital technologies to the achievement of Societal Development Goals.

Keywords: research and innovation,indicators,composite indicators,green transition,technological development,sustainable development goals,internationalization of randd
Voices of Resistance: A Global Micro-Historical Approach to Enslavement across the Atlantic and Indian Ocean (GlobSlav)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2024-06-01
End date: 2029-05-31
Duration (months): 60.0
Total project cost (EUR): 1999999.0
EU funding (EUR): 1999999.0
Participants: 1
Project status: SIGNED

Historiography suggests that the different ways in which people were enslaved (e.g. through war, kidnapping, debt, birth) mattered greatly for how they resisted and were treated under slavery. These links remain largely unexplored, but are vital to re-understanding the history and present of slavery. This project studies how responses to modes of enslavement impacted i) slave trade patterns, ii) labelling and treatment, and iii) strategies of enslaved across the Indian Ocean, Indonesian archipelago and Atlantic. The project employs a global (micro)historical approach to study the uniquely detailed material from colonial court records containing voices of enslaved and other actors as witnesses, victims or accused. These provide a lens on modes of enslavement, practices of slavery and strategies of enslaved that surface both ‘transgressions’ and the considered ‘normal’, creating multiplicities of views on ‘circumstances’ and ‘backgrounds’. Indexation and proven qualitative methods are used to analyse the court records. The rich and increasing digitized colonial archives allow for contextualization strategies and expanding on innovative digital research infrastructure (GLOBALISE). The project team tackles key cases related to the key European empires (Portuguese, Spanish, French, English, Dutch). Fruitful team synergy is created by ‘light’ collective efforts that allow connecting, comparing and analyzing research results from the subprojects (e.g. on the same groups of enslaved, as Balinese, Pulaya or Malagasy, as they occur in different case study regions and archives). The project bridges historiographic gaps between the Indian Ocean and Indonesian archipelago (‘East’) and Atlantic (‘West’). It revisits our understanding of slavery by innovating debates on: i) the global context of nationalized narratives of slavery history, ii) the impact of enslavement in relation to different slavery regimes, and iii) the ‘uniqueness’ of Atlantic slavery and racialization.

Keywords: slavery enslavement indian ocean atlantic
AnBioLED Ancestral Fluorescent Proteins as Biophosphors for Light-Emitting Diodes (AnBioLED)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-01-01
End date: 2024-12-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: CLOSED

Light Emitting Diodes (LEDs) are present in displays of the great majority of devices we use every day, including smartphones, computers, TVs, etc. Unfortunately, they use toxic non-renewable rare-earth materials for their functioning. Fluorescent Proteins (FPs) have already proven to be an eco-friendly alternative, but their performance over time decreases as the intensity of the excitation source increases. This is because FPs have not been naturally or artificially evolved to function as color converters in electronic devices. Since it is not possible to artificially evolve proteins under LED operation conditions (stress), AnBioLED proposes to merge through machine learning evolutionary information (Ancestral Sequence Reconstruction) and computational protein design to identify key mutations in order to improve FPs photo and thermal stability. More importantly, AnBioLED will use experimental results under device operation conditions to reinforce the protein design strategy. The new ancestral FPs will merge the excellent photoluminescence properties of existing FPs with the robustness of their ancestors. AnBioLED novel approach will allow for the first time to optimize existing FPs for LEDs applications.

Keywords: bio hybrid white light emitting diodes,protein engineering,fluorescent proteins,biomaterials
Critiquing Assessements of Decision-Making Capacity (CAD)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 1
Project status: CLOSED

The focus of this project is what it is for an agent to be able to make a decision, and when we should count them as being able to do so. This is a question that has received sustained attention throughout the history of philosophy, and there are many different theories and models of decision-making on offer. Different views of decision-making can have huge practical impact: in various legal and medical contexts, decision-making capacity is assessed in order to determine how people are viewed and treated, including whether they are fit to stand trial, have the right to refuse medical treatment, or are viewed as criminally responsible. Drawing on a range of philosophical, psychological, cognitive scientific, and psychiatric literature, this project will aim to evaluate different philosophical theories of decision-making. The novel contribution of this project, and its particular methodological focus, will be to focus on assessing theories of decision-making by their practical impact - an important, but often-neglected metric for assessing philosophical theories and concepts. As well as further elucidating and clarifying the core question of the nature of decision-making, two key benefits of this project are envisaged. First, a substantive contribution to the question of how decision-making ought to be assessed in the relevant legal and medical contexts. For example, one key focus of the project will be the neglect of external influences (social and environmental) in facilitating decision-making, where currently in many contexts they are treated solely as potential hinderances. Secondly, the project will bring recent work in philosophy of science on 'pluralism' to bear on the question of how legal frameworks and decisions are and ought to be informed by relevant scientific and empirical research and expertise, given their different focuses, goals, and explanatory interests and the impact that this has on their conceptualizations of relevant phenomena.

Keywords: decision making decision making capacity medicine psychiatry mental capacity mental competence
Innovative Facility for Isotope GENeration with Efficient Ion Accelerator (IFIGENEIA)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Panel: Physics
Countries involved: Greece,Slovenia,Cyprus,Bosnia and Herzegovina,Germany,Switzerland
Call: Excellence Hubs (HORIZON-WIDERA-2023-ACCESS-07, 2023)
Start date: 2025-03-01
End date: 2029-02-28
Duration (months): 48.0
Total project cost (EUR): 6000000.0
EU funding (EUR): 6000000.0
Participants: 22
Project status: SIGNED

The IFIGENEIA Excellence Hub aspires to introduce, develop and deliver the complete design study and the precise business plan for the implementation in Europe of the LINear ACcelerator (LINAC) technology in radiation therapy, diagnostic and theranostic procedures. Linear Accelerator technologies offer a unique, compact, cost-effective, and environmentally friendly solution for sustainable production, management, accessibility, and promotion of nuclear medicine and molecular imaging technologies. Unlike current radioisotope production methods, mostly reliant on older nuclear reactors using highly enriched uranium with associated concerns about global availability, safety, and environmental issues, or on cyclotrons limited to a narrow range of radioisotopes, LINACs enable the production of a broader range due to their tunability in energy, targets, and currents. The IFIGENEIA Excellence Hub aims to create the complete design and implementation study for a cutting-edge LINAC facility in the Balkans, by creating in Greece, Slovenia and Cyprus Excellence Hubs dedicated to developing and implement a LINAC-based facility, capable of producing a diverse range of marketable radioisotopes. Interconnected Hubs will collaboratively pursue national and international partnerships to achieve shared strategic goals and improve value chains. The project focuses on a cross-border R&I strategy, an investment plan, and implementing innovative products and services across the hubs. Each Hub will unite regional stakeholders in healthcare, culture, academia, businesses, public sectors, and societal actors, working toward sustainable nuclear medicine and culture in their regions. IFIGENEIA aims to incubate future excellence hubs in the West Balkan region and will provide mentoring to West Balkan countries in the current project. In collaboration with esteemed research centers, IFIGENEIA can create a lasting technological and business framework for nuclear medicine in Europe.

Keywords: linear accelerator,nuclear medicine,radioisotopes,medical imaging