Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Sustainable exploration for orthomagmatic (critical) raw materials in the EU: Charting the road to the green energy transition (SEMACRET)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Finland,Italy,Spain,South Africa,United Kingdom,Portugal,Czechia,Poland,France,Austria,Germany,Denmark
Call: Innovation for responsible EU sourcing of primary raw materials, the foundation of the Green Deal (RIA) (HORIZON-CL4-2021-RESILIENCE-01, 2021)
Start date: 2022-06-01
End date: 2025-10-31
Duration (months): 41.0
Total project cost (EUR): 6672184.25
EU funding (EUR): 6672182.5
Participants: 19
Project status: SIGNED

Critical raw materials (CRMs) are fundamental to the EU industrial value chains and strategic sectors, particularly with regard to the green energy transition. Currently, the EU domestic supply of primary CRMs is below 3% for many important commodities. To obtain an improved understanding of the EU?s critical raw materials potential, discover new ore deposits and thereby increase the internal sourcing of CRMs and secure its raw materials autonomy, the EU aims to boost the exploration and production of CRMs. Orthomagmatic mineral systems host important green transition (critical) raw materials (GTRM) including Ni, Cu, Co, V, Ti, Cr and platinum-group elements (PGE). There are currently only 2 mines in operation producing these metals in the EU, though there is potential for additional mines in several EU countries. This project is designed to develop socially and environmentally sustainable means of exploration for orthomagmatic CRMs. We will apply, for the first time in the EU, the Mineral Systems Approach to guide exploration for orthomagmatic CRMs. We will thereby generate improved ore models for orthomagmatic mineral deposits which will be translated to mappable exploration criteria to delineate areas of high exploration potential, from regional scale to local scale. Through collaboration between geosciences and social sciences the project will also develop methods to promote social awareness of the importance of responsible exploration and mining. Further, we will map the exploration and production potential of CRM in the EU and key CRM supplier countries. Our research will be conducted at five reference sites in Finland, Portugal, Poland and the Czech Republic representing different geological, social and environmental conditions. The ultimate goal is to promote responsible sourcing of CRMs in the EU and diversify the supply from third countries, thereby securing the continued supply of CRMs for EU industries.

Keywords: sustainable exploration,green transition,critical raw material,orthomagmatic ore deposit
HyperSpectral Terahertz neAR-field nanoscope exploiting miniaturized frequency-combs (STAR)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2022-12-01
End date: 2024-05-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

‘STAR’ aims to increase the technology readiness level of the state-of-the-art graphene-integrated, miniaturized frequency comb (FC) quantum cascade laser (QCL), operating at terahertz (THz) frequencies, devised under the ERC consolidator grant ‘SPRINT’, and develop a detector-less sensing/imaging demonstrator apt to the translation of this technology to industrial end-users. The focus is on providing a compact, low-cost, hyperspectral, nanoscale imaging system, which creates amplitude- and phase-resolved images, employing the not-invasive broadband THz-frequency light of a metrological frequency-comb source, without making use of an external detector. This nanoscope ensures 40-100 nm spatial resolution, >100 times smaller than the THz free-space wavelength, coherent detection and mapping of the THz optical response of materials over the continuous 2-5 THz bandwidth provided by a fully stabilized THz QCL FC, with noise-equivalent-power <10pW/√Hz and fast (<ms/pixel) acquisition rates, far exceeding the performances of commercial time-domain spectroscopy near-field systems. Specific objectives are to manufacture a compact, portable and user-friendly THz hyperspectral nanoscope, validate its core technology with commercial end-users and at trade-shows and evaluate opportunities for THz FC self-detection nanoscopy, identifying novel end-user applications, with a detailed market, IPR and regulatory compliance study. By the end of this programme, I plan to identify a solid exploitation route by directly interacting with THz instrument producers and with targeted commercial end-users. Pushing forward a solid commercial exploitation route, STAR prospects new directions and long-term impacts on many interdisciplinary fields crossing engineering, biology, medicine, cultural heritage, material science and quantum technology, and in a frontier frequency domain where electronics and photonics find a fascinating convergence.
Improving quality of life of advanced pancreatic cancer patients through an AI-guided multimodal intervention, combining pain and cachexia management, nutrition, and physical activity (RELEVIUM)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: Germany,Greece,Belgium,Spain,France,Israel,Estonia,Cyprus,Bulgaria
Call: Improved supportive, palliative, survivorship and end-of-life care of cancer patients (HORIZON-HLTH-2021-DISEASE-04, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 5997312.5
EU funding (EUR): 5997312.0
Participants: 19
Project status: SIGNED

Pancreatic cancer has the lowest survival rate amongst other cancers and is responsible for 95,000 deaths every year in the EU. Its treatment is usually palliative, aiming at slowing tumour progression and at symptom management. The main hypothesis of RELEVIUM is that quality of life (QoL) of advanced pancreatic cancer patients can be significantly improved by reducing pain and cachexia through highly personalised nutrition, physical activity, and pain management strategies, in addition to chemotherapy treatment. To achieve this, RELEVIUM will empower patients with digital tools that facilitate patient-doctor communication and enable them to self-manage their disease. RELEVIUM will use (i) a multi-sensor smartwatch and an innovative remote ultrasound patch, (ii) AI algorithms for continuous remote monitoring of pain and sarcopenia, as well as for decision support, and (iii) patient and caregiver applications. Combined, these tools will provide a stream of evidence on symptom progression and will enable physicians to apply personalised care plans. RELEVIUM brings together an interdisciplinary team of experts and will also involve patients and their caregivers in an iterative co-creation process. The project will initially conduct a feasibility and data collection study (RELEVIUM-FDC, n=130). The study aims at optimizing patient adherence and compliance, and at collecting data for the development of the intervention. A five-centre randomized clinical trial (RELEVIUM-RCT) will then evaluate the efficacy of the proposed personalised care plans for advanced pancreatic cancer patients (n=132) in terms of their QoL. Several secondary outcomes will be investigated, such as the cost-effectiveness of the intervention, its potential in increasing health equity and in relieving the stress burden on the patient families. The study outcomes will result in recommendations for integrating remote monitoring and improving QoL outcomes in palliative care for advanced pancreatic cancer

Keywords: digital medicine,pancreatic cancer,supportive care,palliative care
Twinning for Rechargeable Sodium-Ion Battery Research (TwinBat)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Panel: Chemistry
Countries involved: Türkiye,Germany,France
Call: Twinning Bottom-Up (HORIZON-WIDERA-2023-ACCESS-02, 2023)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 1547122.86
EU funding (EUR): 1493417.5
Participants: 5
Project status: SIGNED

The TwinBat project plans to make Gebze Technical University (GTU) a center of attraction in the field of battery research in Türkiye, especially in the field of sodium-ion batteries (NIBs), through the joint efforts of the twinning partners. With mutual benefit at the forefront, the lack of capacity innovation in the field of rechargeable batteries in Türkiye will be addressed through three main efforts: Research, Training and Network. This goal will be achieved by building collaboration with prominent European institutions, including CNRS from France- an internationally recognized laboratory (LRCS) focused on rechargeable batteries, HUB from Germany- an excellent research university that delivers top-level achievements in a wide variety of fields in both national and international comparisons, and in collaboration with industry partners of TIA- founded in 2017 for the development and commercialization of NIBs. Indeed, we are witnessing the rapid development of NIBs nowadays. Recently, both the first electric vehicle powered by sodium-ion cells and the commercial application of first-generation (Gen1) sodium-ion cells in a cordless drill were reported. However, despite these wonderful developments in the NIBs field, a new generation of NIB still needs to be developed to reach the energy density of Li-ion batteries- TwinBat target to develop Gen2 NIBs to be closer to Li-ion (LFP) cells. While the research topic is timely and of immediate relevance, emerging economies like Türkiye must augment their capacity and competitiveness to match the EU's technological competence on this domain. Thus, increasing GTU's visibility and research capacity; enhancing the research profile of academics working in NIBs; and improving the proposal development, project management and IPR skills of administrative staff, will be achieved by investing in individuals and research - in this context, TwinBat is a perfect fit.

Keywords: sodium ion batteries
Collaborative edge-cLoud continuum and Embedded AI for a Visionary industry of thE futuRe (CLEVER)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Research and Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: Italy,Ireland,Netherlands,Germany,Denmark,France,Greece,Israel
Call: HORIZON-KDT-JU-2021-2-RIA-Focus Topic 1-Processing solutions for AI at the edge addressing the design stack and middleware (HORIZON-KDT-JU-2021-2-RIA, 2021)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 14974655.0
EU funding (EUR): 4497177.77
Participants: 21
Project status: SIGNED

CLEVER proposes a series of innovations in the area of hardware accelerators, design stack, and middleware software that revolutionize the ability of edge computing platforms to operate federatedly, leveraging sparse resources that are coordinated to create a powerful swarm of resources. CLEVER technologies will support the deep edge computing paradigm, moving computing services closer to the end user or the source of the data to reduce power consumption, reduce capacity requirements, and latency for mission critical applications. Furthermore, CLEVER will overcome traditional limitations of edge computing in terms of limited resource availability by providing an effective framework for seamless use of federated resources in the edge-cloud continuum. CLEVER will demonstrate processing solutions for AI at the edge through four use cases: (1) digital twin for in-factory optimization, (2) smart agriculture for high yield eco-farms, (3) fully automated material deployment, and (4) augmented reality for shopping sites. Through the achievement of its goals, the CLEVER project will help to position Europe at the forefront of the intelligent edge computing field, enabling growth across many sectors (manufacturing, agriculture, smart environments, augmented reality, and others). By lowering the barriers for utilising edge computing for artificial intelligence applications, CLEVER will open the door for European Industries and SMEs to leverage state of the art technologies, driving their development and growth as leaders in their sectors.

Keywords: artificial intelligence of things aiot,edge cloud continuum,narrowband iot nb iot,in factory optimisation,smart agriculture,digital twin,augmented reality for shopping,intelligence
Biosensors Using Graphene for Infection Diagnostics (BUG-ID)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark,Sweden,Germany,Bulgaria,Spain,Croatia
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 4666237.71
EU funding (EUR): 4564417.32
Participants: 14
Project status: SIGNED

The World Health Organization has emphasized the importance of early and accurate diagnosis of bacterial infections. An ideal diagnostic tool would possess high speed, high throughput, accuracy, low cost and simplicity of use for the clinical laboratory or bed-side applications. Diagnostic tools that possess all these properties currently do not exist. To address this knowledge gap, in the BUG-ID consortium, seven European universities, one research institute, one hospital and six private companies have teamed up. Our consortium will train 15 doctoral candidates with skills in interdisciplinary research, spanning from nanotechnology and materials science to molecular microbiology, biochemistry, infection medicine to AI-based data analysis. Private sector participants will bring their full capacity to bear on intersectoral training, allowing doctoral students to forge links between science and innovation. At the core of the BUG-ID concept is the 2D nanomaterial graphene. Versatile surface chemistry, sensing capacity and possibility of integration with electronic and optical devices will be the key properties of graphene exploited by our consortium. Scientific challenges we will tackle will include the identification of suitable biomarkers for infection in complex environments (background of bacterial commensals), structural engineering of appropriate receptors for identified biomarkers, functionalization of graphene sensors with the receptors and their integration into functional sensors, miniaturization of sensor technology and optimization of complex signal readouts using machine learning techniques and explainable AI. To pave the way for building such game-changing technology, BUG-ID doctoral students will have to work together as a team, drawing competence from distant scientific disciplines, and moving across sectoral boundaries. In doing so, they will receive training that empowers them to become future leaders in science and innovation.

Keywords: bacterial infections,biomarkers,bioreceptors,machine learning for diagnostics,antimicrobial resistance
A holistic approach to training a new generation of scientists in marine biodiscovery (HOTBIO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Norway,Germany,Spain,Ghana,Poland,Belgium,United Kingdom,Italy,Switzerland
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2023-01-01
End date: 2027-06-30
Duration (months): 54.0
Total project cost (EUR): 2716499.31
EU funding (EUR): 2379736.8
Participants: 20
Project status: SIGNED

The HOTBIO consortium will train a new generation of early-stage scientists to take marine microbial natural products from the seabed to the bedside. They will be involved in every stage of the pipeline from microbial isolation through compound purification and identification to making analogues with desirable drug-like properties. They will gain associated skills in access and benefit sharing, intellectual property and entrepreneurship. Students graduating from HOTBIO will be in a unique position to enter a challenging labour market as they will have received multidisciplinary training at world leading research groups in academia as well as at industry partners. Mentorship will be provided by industrial scientists and recent graduates from the MSCA ITN MarPipe. The HOTBIO consortium consists of eight beneficiaries from seven European countries, including two members from non-academic sectors, that will host ten PhD students. Three more PhD students hosted by two Swiss associated partners will be funded by the Swiss State Secretariat for Education, Research and Innovation. In addition to secondments at the partners in Europe, students will also get the opportunity to do secondments in low-to-middle income countries (LMICs) in Africa and Asia to get a deeper understanding of how modern research can be done in resource-limited setting. HOTBIO expands a conventional marine biodiscovery pipeline by including computer aided drug design (CADD), chemical synthesis of optimized compounds (i.e. medicinal chemistry), target deconvolution and extensive ADMET profiling. This will advance the bioactive microbial secondary metabolites to the later stages of preclinical development, and it will also inform the decisions and priorities of what kind of compounds that should be targeted in the initial phase of the drug discovery process. The downstream development will include hit compounds from earlier projects.

Keywords: secondary metabolites,marine microbes,marine biodiscovery,drug discovery,bioactivity,preclinical development,genome mining,dereplication,structure elucidation,chemical synthesis,cadd
Mechanistic Understanding of The Photoexcited Nitroarene-Mediated Olefin Ozonolysis (NOZONE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-06-03
End date: 2026-06-02
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: SIGNED

Olefins are feedstocks readily available from petroleum and vegetable biomass with an integral role in the preparation of high-value materials. In particular, olefin ozonolysis used to introduce oxygen atoms and convert these molecules into a broad spectrum of synthetic intermediates like aldehydes, ketones and carboxylic acids. So far ozonolysis reactions mostly adopted by the bulk chemical industry which uses it on simple materials. The fine chemical sectors (pharmaceutical and agrochemical industries) do not use this reactivity mostly due to safety concerns in handling ozone. The Leonori group has recently demonstrated that photoexcited nitroarenes can be used as ozone surrogates for the oxidative cleavage of olefins. This project seeks to understand the key mechanistic factors that govern the reactivity so that generalization and application by the broad chemical community might be possible. The completion of such a timely and relevant mechanistic project at RWTH Aachen University will be facilitated by generating, transferring, sharing and disseminating knowledge, and will enhance The Researcher’s future career following the training plan envisioned.

Keywords: photoexcited nitroarene,flash laser photolysis,mechanistic studies
Vital Elements and Postcolonial Moves: Forensics as the Art of Paying Attention in a Mediterranean Harbour Town (VITAL ELEMENTS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Netherlands,Tunisia
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2499734.0
EU funding (EUR): 2499734.0
Participants: 2
Project status: SIGNED

For more than a decade, the dead bodies of people who had hoped to cross the Mediterranean have been washing ashore on the beaches of Zarzis, a coastal town in southern Tunisia. This research program starts out from the question: How did these bodies end up here? While in Europe people who are adrift may be seen as evidence of a “migration crisis,” from the African side of the Mediterranean they point to the chronic, (neo-)colonial depletion of livelihoods. To map how life is enduringly made unliveable, this program develops the method of forensics as the art of paying attention. This method will allow us to trail exemplary vital elements—resources crucial for fostering life and livelihood—and the relations between them. Our cases include: the extraction of phosphate, the fishing of sea sponges, the cultivation of tomatoes, the extraction of water, and the leaving behind of industrial waste. To better understand the complexity of, and material semiotic relations between, vital elements, we focus on Zarzis as a nodal point. This will make it possible for team members to visit each other’s sites and to work together in a Method Lab as well as to collaborate with local artists who will help to sensitise us to local concerns in a Vital Elements Atelier. The research program is innovative in three ways: it (1) contributes to a decolonial shift of attention from the “migration crisis” befalling Europe to the “chronic depletion of life” afflicting Africa; (2) develops the method of forensics as an art of paying attention to ethnographically study the complexity of, and the relations between, vital elements and the ways they impact on living and dying; (3) advances the concept of vital elements for materialities that are active, make connections and foster life, or spur on death.

Keywords: postcolonial science and technology studies ethnographic forensics as a social science method material semiotics depletion of livelihoods tunisia