Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
GLOBAL MARITIME DATA EXCHANGE NETWORK (GLOMADAX)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Today, the maritime industry and maritime authorities rely heavily on AIS technology, a well-established International Telecommunication Union (ITU) standard used globally for vessel tracking. However, AIS is becoming outdated as it does not support data exchange and has several limitations and security vulnerabilities. There is broad consensus that improved communication systems are needed to advance digitalisation. To address these limitations, a new VHF Data Exchange System (VDES), commonly referred to as AIS 2.0, has been developed through international collaboration. AIS 2.0 is an upgrade of the current tracking system, incorporating new data channels, significantly increased capacity, and two-way connectivity. This advancement will empower vessel crews with access to a variety of new digital services such as navigational warnings, virtual buoys, route optimisation, emissions reporting, trusted tracking and positioning messages, and streamlined ship clearance at ports. As the first commercial provider of AIS 2.0 satellite connectivity, with one satellite already in orbit, our objective is to build a constellation of 60 satellites. Meanwhile support from the EIC Accelerator will allow us to deliver close to real-time connectivity by developing and launching two new satellites enabling inter-satellite connectivity and network sharing. This presents a unique opportunity to expand our customer base and solidify our position as market leaders. We are targeting the VDES Market, projected to reach €1.7bn in 2024 and grow at a CAGR of 8.5% up to €3.9bn in 2035. Our primary business model consists of providing AIS 2.0 “Connectivity-as-a-Service” to maritime authorities for full AIS 2.0 coverage in their waters, and to commercial services providers. The widespread adoption of AIS 2.0 connectivity will help save lives at sea, reduce pollution from inefficient shipping practices, and enhance the quality of life for sailors worldwide.

Keywords: vdes,maritime communication,ais,maritime satellite connectivity
Hyper-Spectral Laser Induced Fluorescence LiDAR to detect Submerged Oil over Water in real-time on a molecular level. (OWL)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Norway,Estonia
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 3160388.75
EU funding (EUR): 2212272.13
Participants: 2
Project status: SIGNED

Ocean Visuals' project centers on the development and deployment of the Oil-in-Water Locator (OWL), a cutting-edge solution designed to address the complex challenges of monitoring and safeguarding coastal undersea environments. By utilizing advanced Hyperspectral Laser Induced Fluorescence (HLIF) LiDAR sensors, OWL can detect, classify, and quantify oil spills and chemical pollution -quantifying hydrocarbon presence- both on water surfaces and submerged within the depths. This innovation empowers real-time, accurate, and comprehensive surveillance, revolutionizing our ability to protect and manage undersea ecosystems, mitigate environmental damage, and ensure the safety of coastal regions.

Keywords: oil spill,lasers,sensors,quantum electronics,oil detection,submerged oil detection,invisible oil
First-in-class molecular radiotherapeutic to treat epithelial-derived tumours (MOLECURE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2499999.0
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Akiram Tx addresses the global need for innovative and effective therapies for epithelial cancers, particularly for recurrent/metastatic cases where the prognosis remains poor and curative options are limited. Molecular radiotherapy (MRT) holds great promise as a treatment option, as it delivers radiation selectively to targeted locations by attaching a therapeutic radionuclide to a cancer-targeting molecule. This localized and targeted approach can potentially vastly improve treatment outcomes and patients’ QoL. Yet, one of the critical challenges in MRT is identifying suitable targets that are highly expressed on tumour cells but not present in normal tissues. CD44v6, a cell surface cancer-associated antigen, is one of such potential targets. It is overexpressed in various cancers, including head and neck, ovarian, colorectal, and thyroid cancer, making it a molecular footprint for these cancers and a promising target for MRT. Yet, its characteristics make today’s MRT molecules fail to bind to them strongly enough. Akiram has developed 177Lu-AKIR001, a ground-breaking, first-in-class radiopharmaceutical targeting CD44v6 that uses a full-size human antibody as the nuclide carrier. The use of the antibody unlocks an unprecedently high selectivity, specificity, and binding strength, thus enhancing the efficacy and safety of the treatment and minimizing damage to healthy tissues. Akiram’s novel drug qualifies as a theranostic modality and addresses a multi-billion cancer treatment market (>€145 Bn) poised for fast growth in the years to come. To date, Akiram accomplished the pre-clinical validation stage (TRL5) with outstanding results. Now it is time to prove the clinical efficacy of our drug candidate in humans. Therefore, in this EICA project, Akiram will conduct Phase 1 efficacy studies that will serve as a critical milestone in de-risking the project and attracting the full commitment of investors and pharmaceutical companies interested in licensing it.

Keywords: molecular radiotherapy,theranostics,nuclear medicine,epithelial tumors,clinical trials,drug development
Countering Jihadi Insurgencies in Africa: Repress, Resist & Reorder (COUNTERRR)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-03-01
End date: 2030-02-28
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Many African countries, including Libya, Nigeria, Mali, DR Congo, Somalia, and Mozambique, have been affected by violence of jihadist armed groups. These groups pose a distinct threat to social, political, and economic orders across Africa as they violently reject the nation-state and can rely on support from the transnational violent networks of the Islamic State and al-Qaeda. Research has primarily focused on international responses to “violent extremism” in Africa, but international actors do not operate in a vacuum and interact with responses on the ground. If we want to understand and effectively tackle this violent threat, we need to know more about how domestic actors—governments, security forces, and affected communities—counter jihadist armed groups in Africa. Why do some governments repress these groups through domestic security operations, while others invite foreign countries to militarily intervene? Why do some governments respond immediately, while others delay a response to a new jihadist threat? Why do some communities decide to cooperate with jihadist groups, while others opt to resist them? Why do some communities attempt to resist these groups non-violently, while others form self-defence militias to protect themselves? And finally, how do domestic responses to jihadist armed groups reorder security in the region and shape conflict stabilization or escalation? COUNTERRR will deliver crucial analyses of when, how, and why domestic actors repress and resist jihadist armed groups and reorder security. It will adopt an innovative multi-level and multi-method comparative approach focused on variation within and across three countries (Mali, Nigeria, and Mozambique). Understanding how African countries and affected communities respond to jihadist insurgencies will help international actors to coordinate and adjust their responses to benefit from local knowledge and prevent further escalation of conflict.

Keywords: insurgency counterinsurgency repression accommodation civil resistance militias civilian agency
METAmaterials for Structural Optimization and NoIse Control (META-SONIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-04
End date: 2027-09-03
Duration (months): 24.0
Total project cost (EUR): 209914.56
EU funding (EUR): 209914.56
Participants: 1
Project status: SIGNED

Industries like aerospace and automotive constantly demand novel materials that ensure reduced material usage, improving the performance and sustainability of structural components. Panels, crucial structural components in aircraft and automobiles, require lightweight, high-strength, and vibration-attenuating properties. Elastic metamaterials, artificial media engineered to exhibit excellent mechanical properties, offer unconventional approaches to achieve a balance between extreme stiffness and wave manipulation capabilities. The exploitation of metamaterials, however, remains limited due to conflicting requirements, such as (i) enduring realistic workloads, (ii) attenuating vibrations on a wide frequency range, and (iii) reduced component weight. META-SONIC will realize metamaterial-based multifunctional panels optimized to exhibit outstanding performance in structural and wave attenuation roles. Using multi-objective optimization methods, this project will propose the design of multifunctional panels that endure stresses with a high strength-to-weight ratio and manipulate waves in a broadband manner, tailored considering lightweight designs. This approach will close the gap between the current theoretical design of metamaterials and their development for industrial and technological applications. The obtained computational results will be experimentally validated using the manufacturing (3D printing) and testing equipment currently available at the host institution (Universitat Politècnica de València, UPV). The implementation of META-SONIC will allow new paradigms for the design of multifunctional panels that address vibrations safely and cost-effectively, contributing to sustainable manufacturing practices, energy efficiency, and reduced emissions in the aerospace and automotive industries.

Keywords: acoustic metamaterials engineering multi objective optimization low frequency vibration attenuation
Heritage in EuroPe: new techHologies in crAft for prEserving and innovaTing fUtureS (HEPHAESTUS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Denmark,Sweden,Italy,Faroe Islands,Latvia
Call: Traditional crafts for the future: a new approach (HORIZON-CL2-2022-HERITAGE-01, 2022)
Start date: 2023-04-01
End date: 2027-03-31
Duration (months): 48.0
Total project cost (EUR): 3951429.72
EU funding (EUR): 3951429.72
Participants: 13
Project status: SIGNED

Globalised markets, advancements in technology, and changes in the manufacturing have put at risk traditional crafts techniques, which are in danger of disappearing. HEPHAESTUS will map this important knowledge and know-how of ancient techniques and materials, digitalise craft heritage to restore historic artefacts, preserve it in open archives, and mobilise it to innovate craft processes. Our interdisciplinary consortium will conduct R&I activities through ethnographic research, design thinking, and speculative design to bring together cutting-edge technologies with craft processes to make this encounter socially, culturally, environmentally, and economically sustainable. We will create innovative forms of engagement with the public. HEPHAEUSTUS aims: (i) to revive and valorise traditional crafts by combining them with new and emerging cutting-edge technologies through innovative business models for craft sectors growth; (ii) to create a craft-technology driven methodology for bringing together traditional know-how with new cutting edge technologies, circular economy and New Bauhaus principles to innovate sustainably craft processes; (iii) to explore visions for the role of craft in the future, integrating emerging technologies and contributing to the circular economy, by engaging craft communities in a participatory ideation process; (iv) to set up a life-long learning methodology, develop courses, programs, curricula, entrepreneurial and organisational skill sets to create jobs and revive enterprises where tradition meets the future; (v) to establish the first pioneering “Future of Craft” living lab at Bornholm, an action-oriented think tank for circular craft-driven design innovation (vi) and to establish sustainable craft-technology relationships by connecting research and heritage sites, cultural and creative sectors, institutions, universities and other research institutions, regional and national authorities, enterprises and other relevant stakeholders.

Keywords: cutting edge technologies business model innovation social innovation ecosystem mapping
Controling 3D-aromaticity by switchable molecular tweezers (AROMASWITCH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

Aromaticity, a fundamental concept in the field of chemistry, is conventionally associated with planar, conjugated two-dimensional (2D) systems. Despite its theoretical description and potential application in optoelectronic materials, 3D aromaticity induced by strong through space frontier orbital interactions remains so far little explored. AROMASWITCH aims to exploit the complementary expertise and know-how of the host institute and the fellow to delineate the concept of Controlling Spatial Conjugation by the mechanical motion of switchable molecular tweezers. Our hypothesis is that using Ni(II)-porphyrin and/or norcorrole to place persistent, enriched π-electron at both ends of a tweezer will (a) generate three-dimensional through space conjugation in an optimized distance between two “face-to-face” oriented macrocycles and (b) influence the resultant (anti)aromatic character of the whole system. This approach is innovative as such through space π conjugation has not yet been explored in the molecular tweezer. We will develop macrocycles-terminated switchable molecular tweezers (i) to tweak the through space electronic conjugation in an “on” and “off” mode and (ii) to investigate the impact of 3D conjugation on aromatic property-driven photophysical and electrochemical properties. In addition, we will (iii) inspect the three-component tweezer systems in the context of the guest binding study, intercalation of aromatic or antiaromatic motifs and optoelectronics applications. The project will thus enhance our understanding of stimuli-responsive and conformation-dependent 3D communication between (anti)aromatic rings and holds great potential for the development of smart materials with an optoelectronic response.

Keywords: aromaticity,molecular switches,molecular machines
Three-Dimensional Integrated Photonic-Phononic Circuit (TRIFFIC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 2558750.0
EU funding (EUR): 2558750.0
Participants: 1
Project status: SIGNED

The coherent optomechanical interaction between acoustic and optical waves known as stimulated Brillouin scattering (SBS) can enable ultra-high resolution signal processing and narrow linewidth lasers important for next-generation wireless communications, precision sensing, quantum information processing, and many more. But the proliferation of such a unique and powerful technology is currently impeded by fundamental challenges associated with circuit integration of Brillouin optomechanics in a versatile and mass producible material platform such as silicon nitride. The absence of acoustic guiding and the infinitesimal photo-elastic response of standard silicon nitride devices render conventional SBS in this material platform currently out of reach. An innovative approach that breaks with usual paradigms of actuating SBS solely through optical forces in two-dimensional waveguiding circuit is required to overcome these fundamental limitations. The TRIFFIC project aims to actuate and subsequently functionalize SBS in silicon nitride through three-dimensional (3D) integration of gigahertz acoustic wave sources and waveguides with low loss optical circuits. The two orders of magnitude SBS gain enhancement expected from this project will unlock Brillouin optomechanics in silicon nitride circuits for the first time. Using this novel 3D optomechanical platform, I aim to demonstrate a revolutionary concept of on-demand and programmable optomechanics that will transform the field of RF photonics by providing an advanced signal processor with comprehensive spectral control beyond what is currently possible. Further, I will demonstrate Hz-linewidth integrated SBS lasers in the red and blue visible wavelengths that can be integrated with future portable optical atomic clocks and trapped ion quantum computers. The ERC Consolidator will be instrumental for me to achieve these ambitious research objectives that will enable the optomechanics revolution in integrated optics.

Keywords: integrated optics,stimulated brillouin scattering,optomechanics,microwave photonics,optical frequency combs,silicon nitride,lasers
Designing organic molecules as platforms for reversible charge-to-spin conversion with applications in chromophore optimisation and drug discovery (RadicalProtON)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physical and Analytical Chemical Sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-06-01
End date: 2029-05-31
Duration (months): 60.0
Total project cost (EUR): 1498361.25
EU funding (EUR): 1498361.0
Participants: 2
Project status: SIGNED

Chemistry and Biology are governed by molecules and how they interact. Crucially, what glues a molecule together are chemical bonds, made from atoms pairing all their electrons. Although preferred, this is not the only option: in the comparatively rare cases where a molecule presents unpaired electrons, it acquires a fascinating new status that transforms its chemical and biological properties, best described by the acutely apt name of radical. Despite the extraordinary toolset found in radical-bearing molecules, the rather demanding methods to radical formation currently available mean that only very specific molecular architectures can withstand them, inadvertently limiting the scope of their applicability. The aim of this ERC project is to show that reversible diradical formation upon deprotonation is prevalent, and yet unexplored, in general donor-acceptor organic molecules and use this new knowledge to develop novel design criteria in light-emitting molecules and drug discovery. To achieve this unique aim, I will exploit a widespread structural pattern in a novel way, enabling a molecule to reversibly convert its charge and spin and become a diradical. I will first characterise how different molecular constituents (un)favour diradical formation on isolated molecules. I will then establish, for the first time, the role that diradicals play in defining the function of the numerous bioactive molecules sharing the proposed structural pattern. By exposing the overlooked diradical character in general families of deprotonated organic molecules, I will deliver transformative mechanistic understanding on i) the photo physical properties of fluorescent proteins and ii) the reactivity of small molecule drugs, particularly a new class of covalent inhibitors. The field of organic radicals sits at a critical crossroads between Chemistry and Biology, and as such, taking it a step forward has the potential to cross-pollinate research fields and reshape research frontiers.

Keywords: diradicals,epr,drug design,fluorescent proteins