Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Beyond the Secular: Narrativizing religious change in contemporary German novels (BeSec)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The death of God and the disenchantment of the world are central to self-presentations of modernity. At the dawn of the third millennium, however, the worldwide growth of religious fundamentalisms as well as the pluralisation and individualization (but not the disappearance) of faith in the West suggest the need for a more nuanced understanding of the relation between secularity, modernity and religion. This is not only a matter for empirical research in Social, Political and Religious Studies. “Modernity,” “secularity” and “religion” are, in important ways, interpretive categories shaped by cultural narratives through which individuals and societies understand their world. The project “Beyond the Secular” studies a defined corpus of such narratives: contemporary German-language novels which articulate non-secular and religious experiences and worldviews. Through an interdisciplinary methodology combining close reading and narratological analysis with contextual readings in religious sociology, theology, and political philosophy, the project seeks to determine the potential of literature for the perception and narrativization of religious change in late modern societies.

Keywords: fiction,german,religion,transcendence,present,contemporary
Histidine Phosphorylation and Obesity (HisPO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-05-01
End date: 2022-04-30
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: CLOSED

Histidine PhosPhorylation and Obesity Protein histidine phosphorylation is a poorly characterized post-translational modification. Its importance in mammalian cellular function is emerging from the discovery of histidine kinases and phosphatases and their substrates. Recently, histidine phosphorylation has been involved in heart failure and cancer. Obesity and type 2 diabetes remain challenging disorders due to growing prevalence around the world and poorly efficient treatments. Regarding metabolic disorders, histidine phosphorylation state has been associated with insulin secretion regulation in pancreas. However, the role of histidine phosphorylation in insulin sensitivity in liver, skeletal muscle or adipose tissue and/or in obesity is still not known. The main aim of the present project is to determine whether protein histidine phosphorylation plays a role in obesity-associated metabolic dysfunction. Thus, we will determine if obesity modify global histidine phosphorylation level, histidine kinases and phosphatases expression or activity, and specific protein histidine phosphorylation. Then, we will evaluate whether a change of histidine phosphorylation level can impact whole-body glucose metabolism and body weight/composition by using transgenic mice deficient in histidine phosphatases and/or kinases.

Keywords: obesity,insulin resistance,diabetes,histidine phosphorylation
EEN-InnovationJouney PT (EEN-InnovationJourne)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Specific Grant agreement
Countries involved: Portugal,Portugal,Portugal,Portugal,Portugal,Portugal,Portugal
Call: H2020 ENTREPRISE EUROPE NETWORK SGA4 2020-2021 (H2020-EEN-SGA4-2020-2021, 2019)
Start date: 2020-01-01
End date: 2021-12-31
Duration (months): 24.0
Total project cost (EUR): 344736.25
EU funding (EUR): 344736.25
Participants: 11
Project status: CLOSED

The proposal presented by this consortium is a proposal based on the continuity of the work that has been provided within the framework of the EEN-Innovate Plus PT proposal, in 2019, and whose objectives remain and are intended to continue. It should be noted that during 2020/2021, we will initiate new approaches to cope with the challenges posed by the EIC - European Innovation Council – “From Idea to Investment” - which the EEN- InnovationJourney PT now incorporate into this proposal, under the “Consultation of Enterprise Europe Network on the Work Programmes for 2020-2021 COSME and H2020 activities”. Considering the challenges of the EIC, in addition to the SME Instrument there will be new competition schedules to consider, from FTI - Fast Track Innovation and FET - Future and Emerging Technologies, which will require more expertise and tools to accompany companies benefiting from these programs, insofar as each addresses the needs of a particular community in the innovation ecosystem. The challenges posed will require new approaches to the team, and therefore the reinforcement of stakeholders and partners (e.g. Clusters, Financial Institutions, etc.) - creating greater synergies and converting the Network into a "hub and spoke". The envisaged outcome of this project in Portugal is to provide services to 179 SMEs in 2 years, giving priority to all the beneficiaries under the European Innovation Council - Horizon 2020 and its successors. The project will deliver “7-day service packages” to SMEs located in Portugal. The beneficiaries of EIC programs, SME Instrument, FET and FTI projects and its successors, will be supported by the partners, according to the geographical proximity of the companies. The KAM services will also cover the Portuguese Islands, Azores and Madeira, through the coordinator IAPMEI.

Keywords: innovation,journey,pathfinder,accelerator,portugal
Development and testing of innovative Cr Free solution for REmoval of Anodic Layers (Cr Free REAL)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Clean Sky 2
Action type: Research and Innovation actions
Partnership: CS2 (Art-187)
Countries involved: Austria,France
Call: Development and testing of innovative Cr free anodic layers removal solution (H2020-CS2-CFP08-2018-01, 2018)
Start date: 2019-04-01
End date: 2021-09-30
Duration (months): 30.0
Total project cost (EUR): 499062.5
EU funding (EUR): 499062.5
Participants: 3
Project status: CLOSED

In 2024 the use of hexavalent chromium (Cr(VI)) will be forbidden by REACH regulation. Many studies have been carried out to replace Cr(VI)-based coatings for lightweight metals such as aluminium and have resulted in the development of new protective layers (SAA, TSA, Cr(III)-conversion coating). However, the removal of protective oxide layers is still performed with Cr(VI)-based stripping processes. Cr(VI)-free stripping with NaOH leads to deterioration of the substrate if the process time exceeds the specification of the very narrow process window. The Cr Free REAL project aims to develop an innovative process for Cr free removal of anodic layers and conversion layers, which does not deteriorate the aluminium substrate within an applicable process window. Commercially available or literature mentioned Cr(VI) free stripping agents will be tested and evaluated. In the proposed approaches, it is planned to develop innovative acidic or alkaline stripping agents containing additives. Corrosion inhibitors (e.g. oxoanions, cerates, thiourea to prevent corrosive attack during the stripping process), accelerators (e.g. nitrates, glycolic acid to enhance the removal of the oxide layer), surfactants and complexants (to help obtaining a complete and uniform removal of the oxide layer and for increase of bath stability) will be employed. The best performing stripping process will be tested on six types of machined and cast aluminium alloys for removal of Cr(VI)-based and Cr(VI)-free protective layers. The experiments will be performed on lab scale and pre-industrial samples, including complex-shaped parts with a size up to 400*300*200 mm. Specimens which are re-treated with Cr(VI)-free anodic and conversion coatings shall exhibit a corrosion stability with no pits after 500 hours SST and a low fatigue drop, which shall be lower or equal to specimens treated with state-of-the-art processes.

Keywords: anodic layer,chemical conversion,cr free stripping process
Ultrafast charge density wave memory for quantum computing (Umem4QC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Slovenia
Call: ERC-Proof of Concept (ERC-2017-PoC, 2017)
Start date: 2017-07-01
End date: 2018-12-31
Duration (months): 18.0
Total project cost (EUR): 149452.0
EU funding (EUR): 84998.0
Participants: 2
Project status: CLOSED

The goal of the PoC is to take a newly discovered phenomenon in quantum electronic materials into a potentially disruptive memory technology offering unprecedented high speed, low energy consumption combined with low temperature operation. With the PoC grant we aim to establish (i) viability of such memory devices within the scope of ultrafast low-temperature quantum computing and clarify the most important outstanding technical issues for implementation (ii) generate a business plan and asses the timescale for exploitation, and (iii) establish an intellectual property portfolio with an exploitation strategy. The PoC will define key activities, build a value proposition for a startup company and identify customer segments with industry partners. The PoC would also prepare the ground, and establish vital parameters for a next stage of funding within the Quant-ERA-net project and the upcoming Quantum Technology Flagship. This proposal should be viewed against the backdrop of stalled Moore's law, remarkably fast increases in energy consumption of the information technology sector and overall direction of High Performance Computing (HPC) evolving into quantum technology. The successful completion of the PoC would an important contribution to the upcoming EU Quantum Technology Flagship, demonstrating leadership in competition with US, Japanese, and Chinese developments in HPC. The outcome of the project would be a breakthrough technology showcase opening the way to large strides in the development of future high-performance cryogenic computing.

Keywords: memory devisec,non volatile memory,ultrafast memory,low temperature memory,memristor,optical memory
New products from waste PVC flooring and safe end-of-life treatment of plasticisers (CIRCULAR FLOORING)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Enabling the transition towards a green economy and society through eco-innovation
Action type: Research and Innovation actions
Countries involved: Germany,Austria,Germany,Germany,Germany,Germany,Belgium,Greece,Belgium,Belgium,France,France,Netherlands,United Kingdom,United Kingdom,United Kingdom,Luxembourg
Call: Methods to remove hazardous substances and contaminants from secondary raw materials (H2020-SC5-2018-2, 2018)
Start date: 2019-06-01
End date: 2024-05-31
Duration (months): 60.0
Total project cost (EUR): 5387768.25
EU funding (EUR): 5387768.25
Participants: 19
Project status: SIGNED

CIRCULAR FLOORING aims to enable circular use of plasticized PVC (PVC-P) from waste flooring by developing recycling processes that eliminate plasticizers including hazardous phthalic acid esters (e.g. DEHP). We will demonstrate the project results via production of highquality recycled PVC at TRL 5-6, reprocessing of eliminated plasticizers to new phthalate-free plasticizers and re-use of recycled polymers and additives in new flooring applications. Waste flooring will be subjected to the CreaSolv® Process, which dissolves PVC-P from the material mix and eliminates undissolved matter as well as co-dissolved plasticizers in an extractive purification step (>99%). Pure PVC is recovered from the solution and solvents will be reused completely in the process. Using a controlled catalytic reaction, extracted phthalate ester plasticizers will be converted completely (> 99%) to harmless compounds with plasticizing properties. Together with tailor-made additives, both recovered products are integrated in novel PVC flooring designed for circularity. Chemical and mechanical product analysis, process simulation, LCA, SEA, and business modelling will support process development, upscale and product design. The approach addresses exactly the scope of the call because (i) innovative solutions are developed for removing undesirable substances from secondary raw materials, (ii) removed plasticizers and additives pose health or environmental risks and would adversely affect the quality of the recycled materials and (iii) the hazardous compounds are handled safely and destroyed completely. Addressing the 500.000 t PVC flooring market with recommendations on design for recycling and novel circular materials produced at TRL 5-6, the expected impact on the flooring value chain will be substantial. An interdisciplinary team of 4 RTO, 6 industrial partners (3 SME) and 1 non-profit company will finally implement the new circular economy approach into the PVC flooring industry.

Keywords: pvc p,plasticizer,phthalate,dehp,flooring
Organic phases in cells: Elucidating the physical nature of biological liquid droplets (BlobMech)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 1999806.0
EU funding (EUR): 1999806.0
Participants: 1
Project status: SIGNED

Recently it has emerged that ‘membraneless organelles’ a commonly encountered body for compartmentalisation in Eukaryotic cells that include ‘nucleoli’ and ‘stress granules’, are phase separated liquid droplets suspended inside cells, formed from highly mobile disordered proteins. My research has focused on the prediction from physical theory, that the interior of liquid droplets should have very different chemical properties to the exterior dilute phase. By quantitatively analysing model biological liquid droplets formed by the Ddx4N1 protein, we discovered that their interior resembles an organic solvent (DMSO), can melt double stranded DNA, and selects which proteins can enter based on a simple sequence-based algorithm, akin to a chemical solubility rule. The field of biological liquid droplets has largely focused on phenomenological observations. This proposal aims to step beyond this and test the central hypothesis that “intermolecular interactions drive biological liquid droplet formation to create regions of solvent tailored to promote specific chemical functions”. By studying a diverse range of biological liquid droplets, I seek to establish that physico-chemical properties explain both when liquid droplets mix and when they do not, explain which molecules are absorbed and which are not, use these features to predict new properties to design new functionalised sequences using rules based on their fundamental inter-molecular interactions, determine structures of the liquid droplets using NMR and cryo-electron tomography and investigate the effects of liquid droplets on chemical reactivity. This research has the potential to change our understanding of the mechanisms of biochemistry, and use principles from physical chemistry to explain why cells naturally create these regions of effectively organic solvent inside the cell as part of their life cycle.

Keywords: liquid liquid phase separation,nmr spectroscopy,solubility phenomena in complex fluids
Acceptance, Safety and Sustainability Recommendations for Efficient Deployment of UAM (ASSURED-UAM)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Coordination and support actions
Countries involved: Italy,Italy,Italy,Italy,Poland,Poland,Netherlands,Portugal
Call: Cities as climate-resilient, connected multimodal nodes for smart and clean mobility: new approaches towards demonstrating and testing innovative solutions (H2020-MG-2020-SingleStage-INEA, 2020)
Start date: 2021-01-01
End date: 2023-04-30
Duration (months): 28.0
Total project cost (EUR): 1458990.0
EU funding (EUR): 1458990.0
Participants: 9
Project status: SIGNED

Rapidly developing technology in recent years, makes the concept of vertical transport over populated areas real and nearly ready for implementation. The vision of additional dimension added to hitherto nearly flat urban/metropolitan transport system own potential to become a mobility revolution for passengers and unprecedented challenge for cities in numerous aspects. ASSURED-UAM (Acceptability, safety and sustainability recommendations for Efficient Deployment of UAM) aiming at assuring outstanding robustness in terms of safety, sustainability and acceptability of UAM by focusing to: propagate and accommodate aviation best practices, standards, recommendations and organizational solutions into city/municipal administrative and legislative structures responsible for deployment Urban Air Mobility services in near future; To assure broad and comprehensive organisational and policy definition support for authorities, policy makers and urban industry organization in complex process of implementation of vertical modes of transport and integration with horizontal dimensions of urban and peri-urban mobility systems; To become first but robust answer on European Green Deal goals contributing to climate neutral urban transport in 2050; To provide recommendations for integration of surface modes under the umbrella of U-Space Air Traffic Management System (X-TEAM D2D Project). Outline: Multidisciplinary study providing organizational and policy framework for process of introduction of unmanned modes of urban air mobility. In detail: ConOps, Plan for deployment scenarios for 10 use cases within 5, 10 and 15-year’ timeframe, Knowledge base and policy recommendations in 8 languages, standards for products and processes as well as tools for exchange and learning of urban air mobility, project development support and technical assistance in three locations. UAM community integration and wide consultations, cooperation, and synergy with other projects, industry and user groups.

Keywords: urban air mobility life cycle cost standards foresight
Point-of-Care implementation of TB testing with ultra-fast Local Heating PCR (PITBUL)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Germany,Tanzania, United Republic of,Sweden,Latvia
Call: Cross-cutting KETs for diagnostics at the point-of-care (H2020-NMBP-X-KET-2017, 2017)
Start date: 2017-12-01
End date: 2020-11-30
Duration (months): 36.0
Total project cost (EUR): 3858771.25
EU funding (EUR): 3858771.25
Participants: 7
Project status: CLOSED

The overall goal of this project is to bring the unique, ultra-fast Local Heating PCR technology and its current lab-proven prototype instruments from TRL 4 up to TRL 6 into clinical demonstration in tuberculosis centers in Italy, Latvia, and Tanzania. This will imply a fully automated workflow on the instrument and all necessary reagents onboard of the integrated disposable cartridge, and a cloud based software for tracking epidemiological patterns. The application, ultra-fast point-of-care testing (POCT) for tuberculosis (TB) as well as emerging TB resistance markers, is an unmet healthcare need, not only in Europe, but globally. About one third of the human population is thought to carry the pathogen. One patient with active TB can typically infect 10-15 others. In the EU, the highest incidence rates are observed in Eastern Europe and the Baltic region. Furthermore, a very recent surge has been observed in some EU countries, e.g. in Germany, mainly due to higher mobility and migration. On top of this, multi-drug resistant (MDR) TB strains are becoming epidemic, causing exploding treatment costs. Active tuberculosis needs to be rapidly detected at hospitals, in- and out-patient clinics, specialized TB centers, jails, community centers, and shelter facilities. Such a test should be highly sensitive and capture all of the clinically relevant mutations that confer resistance in TB; if only one mutation escapes detection, the wrong treatment decision might be made, leaving the patient infected and capable of spreading resistant pathogens. Therefore, a panel of multiplexed markers will be adopted to LPCR in this project. It is ultimately the project’s ambition to develop a European-based contender in the emerging molecular POCT system space. The integrated TB/MDR TB LPCR system, a break-through-technology, aims specifically at impacting healthcare, TB knowledge and capacity building, and enabling future commercial success of the products.

Keywords: diagnostics,laser pcr,tuberculosis,multi drug resistant,cloud based software,ultra fast,point of care
Biased Artificial Intelligence: Openness, innovation and the remaking of mental health (Biased AI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 172800.0
EU funding (EUR): 172800.0
Participants: 1
Project status: CLOSED

Following trends to design Artificial Intelligence (AI) for Good, (a plea to develop AI in ways addressing pressing problems that face humanity), the focal question we will address is: What is the proper combination of open and proprietary elements in AI innovation in the field of mental health in light of the need to design a system that both promotes innovation and is compatible with the ideals of human dignity, fundamental rights and freedoms, and cultural diversity? Our concern in the context of mental health in particular is that proprietary AI may reproduce gender and racial stereotypes, which in turn may reinforce social stigma and raise a barrier to proper diagnosis and treatments. On the other hand, the present research does not entertain a model of innovation where the proprietary stands in opposition to the open. Rolling back private property does not necessarily favour the weak over the strong. To this effect, we propose to conduct qualitative research to identify public and commercial demands in order to rethink the governance of innovation in AI, focusing in particular on mental health. Participant observation and Interviews with key stakeholders will be conducted to elicit their views, taking into account not only economic but also ethical aspects (diversity, rights and freedoms). The governance question needs to take into account public demands that are technically feasible and at the same time commercially viable in the AI area.

Keywords: artificial intelligence,bias,mental health,innovation,intellectual property,bioethics