Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Lobbying and framing in foreign policy. EU and member states’ foreign policies towards Israel and Palestine (LOBFRAM)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-09-01
End date: 2018-02-23
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

LOBFRAM aims to advance our understanding of lobbying and framing in foreign policy in the European Union’s (EU) system of multi-level governance. While lobbying in the EU has received a lot of attention in recent years, lobbying in foreign policy remains a largely under-researched topic. Therefore, this project will explore the activities of non-state actors (NSAs), such as business groups, NGOs and solidarity movements, in EU foreign policy, investigating the networks that are established at different levels (EU and member states) and framing processes. The main contribution of LOBFRAM will be to investigate networks as transmitters of ideas. In turn, this will help us to analyse how frames are created, get codified and become collective frames influencing foreign policy at both the EU and member state levels, as well as what mechanisms of mutual interaction exist between EU and national foreign policy positions. LOBFRAM will be based on an interdisciplinary approach building on international relations, EU studies, sociology and organizational studies and will rely on a mixed-methods approach. It will focus on the case study of the Israeli-Palestinian conflict, which is one of the most important policy issues on the EU and member states’ agenda, also in light of the strong commercial links with Israel, the crucial role as donors for the Palestinians and historical legacies. The project will zoom-in on three big member states, namely the United Kingdom, Germany and France, and identify similarities and differences among these member states as well as between them and the EU level when it comes to lobbying and framing activities. The findings of this project will be published in a monograph and two journal articles and widely publicized to a non-specialised audience via outreach activities (e.g. a dedicated website, one policy brief and activities for students).

Keywords: lobbying,framing,non state actors,foreign policy,european union,europeanization
Tumor and Lymph Node on Chip for cancer studies (Tumor-LN-oC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: Research and Innovation actions
Countries involved: Austria,Spain,Finland,Greece,Switzerland,Greece,France,Czechia,Netherlands,United Kingdom
Call: Next generation organ-on-chip (RIA-LS) (H2020-NMBP-TR-IND-2020-twostage, 2020)
Start date: 2021-05-01
End date: 2025-04-30
Duration (months): 48.0
Total project cost (EUR): 6806591.96
EU funding (EUR): 5769436.25
Participants: 11
Project status: SIGNED

The lymphatic system and lymph nodes (LNs) are an integral part of our adaptive immune system and many tumors exploit lymphatic vessels to spread and colonize downstream LNs. Tumor-LN-oC aims to offer a comprehensive solution for a robust, automated tumor-lymph node-on-chip platform that will connect primary surgically removed human tumors and LN tissue from the same cancer patient. This will allow us to study the interaction of primary tumors with lymph nodes, identify their chemical signature, and offer personalized treatment relying on molecular characterization of lymph node metastasizing cells. The project will significantly advance the fields of microfluidics, cell biology, cancer biology, physics, and computer programming and software development, by pursuing the following objectives: a) To introduce novel designs and develop robust, automated microfluidic chips optimized for tumor cell and LN culture enabling the study of their crosstalk, b) To integrate Quantum Cascade Laser based mid-IR spectroscopy for specific chemical signatures, c) To molecularly characterize both migrating tumor-derived cells attracted to the LN and the soluble signals driving migration, d) To demonstrate an advanced image analysis and signal processing platform using deep learning algorithms facilitated by a micro-optics module to monitor in real time the cells migration, e) To integrate all Tumor-LN-oC technologies in an automated platform prototype incorporating interfaces compatible with existing laboratory equipment. The Tumor-LN-oC platform, will be developed at TRL5 and will be validated using real patient samples. Regulatory pathways, standards and requirements compliance will be considered in order to facilitate exploitation and early market entry. The consortium encompasses key – industrial partners and experts in the aforementioned interdisciplinary fields and is expected to have substantial impact in EU’s economy and healthcare.

Keywords: organ on chip,lymph node,tumor on chip,tumor migration,bioprinting,microfluidics
Quantum Probes for Complex Systems (QuProCS)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Emerging themes and communities
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Italy,Spain,China,Finland,United Kingdom,United Kingdom
Call: Quantum simulation (H2020-FETPROACT-2014, 2014)
Start date: 2015-04-01
End date: 2018-03-31
Duration (months): 36.0
Total project cost (EUR): 2268746.25
EU funding (EUR): 2268746.0
Participants: 8
Project status: CLOSED

We are on the verge of a new scientific and technological era as the first quantum simulators able to investigate physical systems that cannot be studied classically are about to be built in the laboratories. Controlling and probing complex quantum systems is of paramount importance for the implementation of these devices. Quantum simulators are controllable complex quantum systems that emulate the behaviour of other quantum systems whose properties cannot be easily tested. While several models of quantum simulators are currently under construction, the development of effective probing techniques is still lagging behind, despite their crucial role. In most of the quantum simulator experiments measurement techniques are invasive and destructive, destroying not only the very quantum properties from which the simulator stems, but often also the quantum system itself. QuProCS works on the development of a radically new approach to probe complex quantum systems for quantum simulations, based on the quantification and optimisation of the information that can be extracted by an immersed quantum probe as opposed to a classical one. The team will theoretically investigate and experimentally implement quantum information probes to detect and characterise quantum correlations, quantum phase transitions, transport properties, and nonequilibrium phenomena in ultracold gases. By a shift in perspective to a complementary viewpoint, we will at the same time investigate experimentally, in a quantum optical platform, how changing the properties of the environment via reservoir engineering modifies the behaviour of the quantum probe. We will develop optimal probing strategies to read out and benchmark quantum simulators, thus providing the most crucial ingredient for commercial devices.

Keywords: complex quantum systems,many body systems,open,quantum systems,non markovian dynamics,quantum information and computation,quantum measurement
Grassfibre raw material and grasspaper products for the retail, paper and packaging industry, helping to reduce plastic and textile pollution and CO2 emissions on a global scale (Grasspaper)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2021-02-01
End date: 2023-01-31
Duration (months): 24.0
Total project cost (EUR): 2141250.0
EU funding (EUR): 1498875.0
Participants: 1
Project status: CLOSED

With grassfibre Creapaper introduces a highly innovative, sustainable and cost-efficient alternative raw material for the European paper industry. About half of the 400 million tons paper produced worldwide every year are based on wood pulp. This consumes about 40% of the global industrial wood harvest. Moreover, transport and processing of the wood consume a lot of water, chemicals and energy. Costs and impact to nature are severe. Creapaper provides an unique solution to this problems by introducing grassfibres, produced by a novel patented mechanical process, as a new resource for the paper industry which is compatible to standard production equipment. Grasspaper products are free of noxious substances, printable and have a distinctive sustainable, yet premium appearance and up to 75% of CO2 emissions are saved. They are therefore very attractive for packaging and to replace single-use plastics. Several awards in the packaging industry and first orders from large, well-known brands confirm these USPs of grasspaper products. While Creapaper's customers are paper mills, also brand owners and retailers are addressed with own designs and mock ups. This increases the demand for grasspaper and grassfibres rapidly and will allow a fast scale-up in the European key markets. We started establishing grassfibre as the paper industry's third raw material source besides wood pulp and waste-paper. Creapaper installed a first grassfibre production centre. In the project we will modify and optimise the production process, as well as grasspaper and coating properties, to allow cost-efficient mass production of grasspaper products. As the next step of ecologocal packaging materials also adding to circular economy, 100% treeless grass-textile paper, unsing textile waste and grass is developed to market readiness. This next stage in our commercialisation strategy allows us to evolve our business model from grassfibre and grasspaper towards grasspaper products to substitute single-use plastics like straws, cups, and bags.

Keywords: grass,grasspaper,grassfibre,alternative fibre source,virgin fibre,pulp,non wood paper,eco friendly,forest protection,paper revolution,packaging,waste fibre recycling,treeless paper
High performance low cost electric propulsion system development (HiperLoc-EP)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling European competitiveness, non-dependence and innovation of the European space sector
Action type: Research and Innovation actions
Countries involved: Sweden,Netherlands,United Kingdom,United Kingdom
Call: SRC - In-Space electrical propulsion and station keeping - Disruptive Technologies (H2020-COMPET-2016, 2016)
Start date: 2017-01-01
End date: 2019-06-30
Duration (months): 30.0
Total project cost (EUR): 1385975.0
EU funding (EUR): 1385974.25
Participants: 4
Project status: CLOSED

The HiperLoc-EP project will develop a disruptive electric propulsion technology that provides a High performance Low cost Electric Propulsion system. HiperLoc-EP will provide critical propulsion functionality for micro satellite and satellite constellations typified by Samsung’s Earth-wide internet via 4600 micro-satellites. The HiperLoc-EP technology is an Electrospray Colloid Electric Propulsion System (ECEPS). The design approach is radical. The element of the EP system that develops thrust is completely integrated with the Power Processing Unit; the thrust head itself is a multilayer PCB. Core to our methodology is a novel route to manufacturing an EP system, it is inspired by a system we have successfully used in another technology domain in terrestrial applications. Fabrication, integration and propellant costs are anticipated to be several orders of magnitude below conventional EP procurement. The potential applications for this technology are very broad however, in response to the COMPET-3-2016b we will focus the development on micro propulsion consistent with satellites having mass spanning the range from a multi-unit CubeSat to small satellites less than 100kg. The performance target is a thruster whose efficiency is ~50%, some 6 times that possible with typical current PPT designs, but comparable to conventional EP such as GIE and HET. The ECEPS can be designed to operate over a broad range of Isp from ~1000s to ~4000s; herein and consistent with resources of micro-satellites we will demonstrate an Isp of 2500s. ECEPS thrust scales with thrust head active area, anticipated to be ~0.2mN/cm2. This new electric propulsion system will have low volume and low power demands and is ideally suited to micro satellite constraints. This emerging technology will clearly disrupt the status quo of the space sector by providing a radical improvement in performance and cost, critical to customers hoping to operate in the dawning market for micro-satellite based systems.

Keywords: electrospray colloid thruster,micro satellite electric propulsion,cubesat electric propulsion,high specific impulse low cost electric propulsion
Designing eTrading Solutions for Electricity Balancing and Redispatching in Europe (FutureFlow)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: A single, smart European electricity grid
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Serbia,Hungary,Romania,Slovenia,Slovenia,Belgium,France
Call: Transmission grid and wholesale market (H2020-LCE-2015-3, 2015)
Start date: 2016-01-01
End date: 2019-12-31
Duration (months): 48.0
Total project cost (EUR): 12985242.5
EU funding (EUR): 12985233.5
Participants: 20
Project status: CLOSED

Four European TSOs of Central-Eastern Europe (Austria, Hungary, Romania, Slovenia), associated with power system experts, electricity retailers, IT providers and renewable electricity providers, propose to design a unique regional cooperation scheme: it aims at opening Balancing and Redispatching markets to new sources of flexibility and supporting such sources to act on such markets competitively. Thanks to a prototype aggregation solution and renewable generation forecasting techniques, flexibility providers – distributed generators (DG) and Commercial and Industrial (C&I) consumers providing demand response (DR) – are enabled, through retailers acting as flexibility aggregators, to provide competitive offers for Frequency Restoration Reserve (including secondary control activated with a response time between 30 seconds and 15 minutes). A comprehensive techno-economic model for the cross-border integration of such services involves a common activation function (CAF) tailored to congested borders and optimized to overcome critical intra-regional barriers. The resulting CAF is implemented into a prototype Regional Balancing and Redispatching Platform, securely integrated within the four TSOs’ IT systems: this makes research activities about cross-border integration flexible while linking with the aggregation solution. Use cases of growing complexity are pilot tested, going from the involvement of DR and DG into national balancing markets to cross-border competition between flexibility aggregators. Based on past experience with tertiary reserve, participating C&I consumers and DG are expected to provide close to 40MW of secondary reserve. Impact analyses of the pilot tests together with dissemination activities towards all the stakeholders of the electricity value chain will recommend business models and deployment roadmaps for the most promising use cases, which, in turn, contribute to the practical implementation of the European Balancing Target Model by 2020.

Keywords: balancing,redispatching,ancillary services,secondary control,afrr,it integration,flexibility,aggregation,cross border cooperation,cyber security,renewable generation forecasting
Food for thought: monitoring the effects of drugs and diet on neuronal glutamate release using nanoelectrodes (F4TGLUT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 191852.16
EU funding (EUR): 191852.16
Participants: 1
Project status: CLOSED

Glutamate is the primary activating neurotransmitter in the brain. It modulates synaptic plasticity of neurons, which underlies memory formation. However, it also plays a fundamental role in pathological processes, such as those related to Alzheimer’s disease. This essential role and future development of therapeutic agents urge the development of a highly-sensitive analytical method for determining glutamate levels at a cellular level. In this project I will create a miniaturized, in vitro system that will allow this. To develop it, my expertise in microfluidics and pharmacy will be supplemented by the host’s extensive experience with cell analysis and nanoelectrodes. When glutamate-type neurons in the brain are innervated, glutamate release into the synapse between adjacent neurons occurs. This triggers chemical signal transmission. Nanoelectrodes are uniquely equipped to monitor this neurotransmitter release with unprecedented spatiotemporal resolution. The combination with microfluidics will allow control of fluids and experiments at the nanoliter scale. Furthermore, through precisely fabricated microstructures, guidance of cell growth and precise placement of the nanoelectrodes in the device will be achieved. Glutamate modulates synaptic plasticity, a phenomenon understood to underlie memory formation. Furthermore, dietary compounds and drugs can influence glutamate neurotransmission. The proposed system enables selective exposure of individual neurons cultured in the microfluidic device to such compounds. Using the integrated nanoelectrodes, direct monitoring of their effects on chemical signaling between cells will be possible. The results will significantly contribute to our understanding of glutamate neurotransmission, and how drugs and diet can influence it. Additionally, the system combines cell culture, selective exposure and analyses at the cellular level using sensors and imaging, making it an ideal platform for future drug development research.

Keywords: glutamate,neurons,nanoelectrodes,microfluidics,zinc,lipids,memory
Single Cell approaches for the study of oncogenic processes during coeliac disease. (SingCelCD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

Coeliac disease is a chronic autoimmune-like enteropathy induced by dietary gluten in 0.5-2% Europeans. A rare but specific complication is the onset of invasive enteropathy-associated lymphomas. The host laboratory has demonstrated that in approximately 70% of CD patients, invasive lymphomas are preceded by a clonal low-grade intraepithelial lymphoproliferation, usually called type II refractory CD (RCDII). I intend to take advantage of my experience in cellular immunology and single-cell analyses: 1- to analyse the peri-tumor microenvironment and search for anti-tumoral T cell response in RCDII; and 2- to analyse the functional intra-clonal heterogeneity among RCDII malignant cells. The results should provide further insight into the mechanisms, which control disease progression and will help us to assess therapeutic strategies. This project will complete and extend the on-going genomic analysis of lymphomas complicating CD. It will notably help to assess if the JAK1/STAT3 pathway is a pertinent therapeutic target and the possible interest of checkpoint inhibitors. To achieve the aims of the innovative translational project, I will integrate one of the European leader research center in genetic diseases, giving me the opportunity to gain experience in translational immunology and human genetics, as well as to reinforce my expertise in cutting-edge single cell technologies and bioinformatics. Overall this project represents a unique stepping-stone to complete my training in pathophysiology and establish collaborations, which should put me in excellent position to establish as an independent researcher.

Keywords: coeliac disease,lymphoma,single cell analysis
Wave-based Room Acoustics Modeling (WRAM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2016-12-01
End date: 2018-05-31
Duration (months): 18.0
Total project cost (EUR): 149138.0
EU funding (EUR): 149138.0
Participants: 1
Project status: CLOSED

Virtual acoustics is the complete simulation of the listener’s experience in an acoustic space. The applications are many: building acoustics, concert hall design, and virtual reality, including immersive game audio. Conventional audio rendering approaches are based on geometric or ray-based approximations. Though conceptually simple, such methods neglect many audible features of room acoustics, and in particular are not valid at low audible frequencies, or capable of rendering diffraction or shadowing effects around corners or obstructions. Wave-based methods address the shortcomings of ray-based methods, yielding a complete description of the acoustic field within an enclosure. The NESS project (ERC-2011-StG-279068-NESS) has taken wave-based methods from theory to the practical setting of real-world room acoustics, resulting in many key innovations, including the modelling of arbitrary geometries, variable and frequency-dependent wall conditions, and viscothermal effects in air. Building on these innovations, the aim of the proposed ERC PoC project WRAM (Wave-based Room Acoustics Modeling) is to introduce a new generation of sophisticated virtual acoustics rendering tools to the wide market of architectural acoustics, and immersive and game audio practitioners. The main activities under WRAM will be the development of a prototype system for wave-based high-quality room acoustics renderings, to operate ultimately as an on-demand cloud-based service. The development of the WRAM system will be informed by extensive consultation with a wide variety of industrial sectors, with regard to the design of several benchmarking problems, which will be tested against industry-standard ray-based platforms, and compared against measurement. From our interaction with industrial partners, we will build a business case based on a detailed market analysis and investigate possibilities of further investment by potential commercial partners and the strengthening of our IP position.

Keywords: room acoustics,game audio,virtual reality