Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
2D sandwiches, artificial layered building blocks for multifunctional materials (2D-sandwich)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Materials Engineering
Panel description: Advanced materials development: performance enhancement, modelling, large -scale preparation, modification, tailoring, optimisation, novel  and combined use of materials, etc.
Countries involved: Czechia
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 1975955.0
EU funding (EUR): 1975955.0
Participants: 1
Project status: SIGNED

The possibility to create new materials bottom-up was enhanced via the stacking of atomically thin layers of two-dimensional (2D) materials with van der Waals interactions (vdWIs). Unfortunately, the downside of vdWIs is the, in general, weak electronical and mechanical interaction between the individual layers. This hinders the creation of multiferroic materials working at ambient conditions, which are despite extensive research still very scarce, from stacked layers with vdWIs. This research aims to create a new 2D building block: the 2D sandwich. This is a layered heterostructure with a strong interaction between the sandwich's individual layers mediated via an ionic or multivalent bond, whereas the interaction with other layers is still solely due to the vdWIs. As the prototype functional material, a 2D magnetoelectric multiferroic sandwich composed of layered transition metal chalcogenides, oxides or iodides will be grown using the modulated elemental reactants method. To tackle the possible sample degradation in the sandwiches, ultra-high vacuum optical surface science spectro-microscopy techniques will be developed to optically probe the 2D multiferroic sandwiches for both magnetism, ferroelectricity and the coupling between them. The concept of open samples will be introduced, facilitating the scientific community with the straightforward verification of the data and accelerate the development of this new class of 2D sandwiches. This project will provide material design strategies that can remove the stringent lattice matching criteria to stack different classes of layered materials and provide these class of layered materials with similar stacking freedom as layered materials with vdWIs. These insights will allow the interbreeding of different classes of layered quantum materials, such as complex oxides, 2D layered crystals with vdWIs, cuprate superconductors or topological insulators or semimetals.

Keywords: heterostructure,multiferroic,van der waals interactions,ionic bonding,multivalent bonding,modulated elemental reactants method
The World’s First Autonomous Blood Drawing Device (VD-1)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2023-06-01
End date: 2025-02-28
Duration (months): 21.0
Total project cost (EUR): 2975301.25
EU funding (EUR): 2082710.88
Participants: 2
Project status: CLOSED

Vitestro has created the first fully-autonomous device that draws blood from patients. Our solution, called VD-1, performs the whole venipuncture procedure, from vein detection to bandage application, without any human intervention. We have fully developed our technology in-house and protected it with seven patents. More than 1,000 volunteers have tried our solution: the user acceptance, first-time success rate, and hemolysis rate are comparable to those measured using human nurses. The VD-1 will mitigate the chronic shortage of healthcare personnel. It will also standardize the venipuncture process, which has been substantially unchanged for decades. We target two categories of customers – lab chains and hospital labs – and we have launching customers in both of them. Vitestro has a team of nearly 50 people, including technical, medical, regulatory, and commercial expertise.

Keywords: improving patient outcome,ai image recognition,cost reduction in healthcare,medical errors,automation,robotic phlebotomy,patient experience,clinical laboratory,blood drawing
Language on the move (LangMov): an investigation of Dâw motion categories in context (LangMov)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 206887.68
EU funding (EUR): 206887.68
Participants: 1
Project status: CLOSED

This project proposes a novel investigation of the concept of mobility among mobile hunter-gatherer groups through the lens of language. It will do so by examining verbs of motion – a bona fide linguistic category reflecting mobility – in indigenous lexicons and grammars. But what can verbs of motion tell us about hunter-gatherer mobility? And, how can occurrences of motion verbs map onto identifiable environmental and cultural features of a given society? Here, I explore these questions treating Dâw (Naduhup; Northwest Amazonia) as a focal case. Dâw is ideal for examining this topic because it harbors a rich system of motion verbs and a typologically unusual pattern of motion event encoding; it heavily encodes the notion of the terrain in the verb. I will conduct an innovative investigation into hunter-gatherer representations of motion as these unfold in the Dâw peoples’ surroundings while speakers are on the move. While walking, semi-structured interviews will be performed in which speakers will be asked to describe what kind of motion they are performing. This will be recorded in audio, video and GPS for subsequent exploration of the motion verb usage and meanings in relation to measurable topographical features. A second layer of analysis will be provided by speakers’ posterior descriptions of the respective motion events. Multi-factorial analyses, bringing together measurable spatial manifestations and speakers’ perceptions of a motion event will result in a record of geographically mapped motion categories. Hence, I pursue the overall goal of substantially advancing our understanding of the linguistic encoding of motion in its language-and-culture-specific and motion-related context. This will both deepen our knowledge of the representation of mobility in a cultural context, which is of crucial concern to human history and diversity, and at the same time advance our understanding of motion semantics at the intersection of language, culture, and environment.

Keywords: hunter gatherer mobility motion verbs semantics of motion event encoding language description language documentation linguistic anthropology gis topography indigenous languages
Novel technologies for on-site and remote collaborative enriched monitoring to detect structural and chemical damages in cultural heritage assets (ChemiNova)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Ukraine,Germany,Austria,Greece,Romania,France
Call: Advanced technologies for remote monitoring of heritage monuments and artefacts (HORIZON-CL2-2023-HERITAGE-01, 2023)
Start date: 2024-02-01
End date: 2027-01-31
Duration (months): 36.0
Total project cost (EUR): 3477816.25
EU funding (EUR): 3477816.25
Participants: 13
Project status: SIGNED

What if EU citizens could collaborate with scientists in the preservation of cultural heritage? Could conservation professionals be provided with actionable technologies, skills and frameworks that upgrade their efficiency? Europe's cultural heritage is a rich and diverse melting pot of traditions, monuments and communities where we have boiled our identity, well-being and sense of belonging. Nonetheless, in recent years, we have witnessed a series of natural and human-induced disasters that threaten it. Improving cultural heritage resilience to climate change and anthropogenic hazards requires a shift in conservation practices towards more holistic ones. ChemiNova aims to develop an intelligent computational system that goes beyond current technologies to improve the conservation, analysis and monitoring of European cultural heritage assets. Using a myriad of data, we will tackle structural and chemical damages, focusing on two specific human-induced threats: climate change and civil conflicts. Furthermore, our impact lies in the fact that we will not build an ad hoc device, but our technology is adapted so that anyone can access it from anywhere. We will involve local communities in conservation practices, from providing data (citizen science) to raising awareness on the effects of climate change, natural and human hazards affecting CH. As a main objective, we will develop novel and cost-effective ways for remote and on-site monitoring of cultural heritage assets by reusing existing technologies and providing conservators with advanced analysis of structural and chemical damages due to human-induced threats. Also, it will involve heritage practitioners and non-experts in conservation processes, while considering end-users at the centre of our tools and methods. ChemiNova considers a set of non-destructive and portable technologies in a modular way that will allow adaptable inspections according to the different case scenarios, monuments, buildings and artefacts.

Keywords: damage prediction,virtual replicas,real time,collaboration,mixed reality,climate change,areas in conflict
PAH-ADVANCE: Accelerating the Clinical Path of NTP42, a disease-modifying drug that will disrupt the future treatment of cardiopulmonary diseases, including pulmonary arterial hypertension (PAH). (PAH-Advance)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Ireland
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-01-01
End date: 2023-12-31
Duration (months): 12.0
Total project cost (EUR): 4181504.25
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

ATXA Therapeutics has developed NTP42, a disruptive new drug for pulmonary arterial hypertension (PAH) and related cardiopulmonary (heart & lung) diseases. NTP42 blocks the thromboxane receptor, a target at the root cause of PAH & related diseases. By treating all clinical hallmarks in both the LUNGS and HEART, NTP42 offers a game-changing solution for PAH leading to its rapid adoption once marketed. ATXA’s Phase I clinical trial showed NTP42 is safe & highly efficacious in man. With EIC Blended Finance and VC co-investment, ATXA will undertake a Phase II trial on NTP42 in PAH. We will then secure a licensing deal with a pharma to ACCELERATE NTP42 to the PAH market (sales >$1B at 5 yrs post-launch & royalty returns to ATXA). With the proceeds of the licensing deal, we will DIVERSIFY uses of NTP42/pipeline drugs to treat other priority target diseases. This will also ENABLE growth (>100 FTEs), transforming ATXA into a major European pharma with a diversified diseases & drugs portfolio.
Profile nucleases and Repurpose Off-Targets to Expand Gene Editing (PROTEGE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative B iology : from Genes and Genomes to S ystems
Panel description: For all organis ms: Genetics, epigenetics, genomics  and other ‘omics studies , bioinformatics, systems biology , genetic diseases , gene editing, innovative methods and modelling,  ‘omics for personalised  medicine
Countries involved: Lithuania
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 1141779.0
EU funding (EUR): 1141779.0
Participants: 1
Project status: SIGNED

Programmable nucleases reside at the nexus of advanced gene editing and microbial defense. These nucleases degrade phage DNA but avoid genomic DNA to provide the microbe with adaptive immunity. The standard-bearer, CRISPR-Cas9, relies on a guide RNA (gRNA) – its program – to precisely cut a complimentary genetic sequence – its target – for precision gene editing. These programmable nucleases deliver cure for genetic diseases like anemia, blindness, and cancer; quick disease model development; and diagnostics for viruses like SARS-CoV-2. Hunts across microbial genomes have exposed thousands of programmable nucleases. Each could be another valuable tool for genome engineers, but we know just too little about them to use them safely. Even Cas9 does not have guide-target parity: It cuts partially matched ‘off-target’ genome sites, which can lead to dangerous side effects. Though we work hard to avoid off-targets, partial matching may have a bright side. What if we leverage it, using it to make gene editing more predictable? Using high-throughput biochemistry, we will Profile nucleases and Repurpose Off-Targets to Expand Gene Editing. The PROTÉGÉ research program will profile guide-target parity – specificity – across promising, newly discovered programmable nucleases. It will deliver a toolset for assessing this critical safety feature rapidly and broadly. Finally, we will test the hypothesis that purposefully misprogramming nucleases can direct specific repair outcomes. We intended to benefit Europe and the world community with safer and more diverse gene editing tools for achieving its Horizon Europe health, technology and environmental goals.
The world’s most efficient heat engine: Turning heat into zero-emission electricity for industrial and geothermal applications (Lava Heat Engine)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Israel
Call: Renewable energy sources and their whole value chain including materials development and recycling of components (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 3571427.14
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

At Luminescent we specialise in proprietary liquid-based isothermal heat engine technology, a disruptive innovation in the renewable energy sector. Our Lava heat engine is designed to harness a wide range of thermal energy from various industrial processes and turn it into a valuable commodity: electricity. This innovative approach not only elevates the efficiency of industrial operations but also contributes significantly to sustainability by generating clean, green power from untapped heat sources.

Keywords: heat engine,renewable energy,geothermal energy,electricity,carnot efficiency
HIGHLY EFFICIENT CO2-TO-SYNTHETIC FUEL PRODUCTION PROCESS (CAPHENIA)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2490000.0
EU funding (EUR): 2490000.0
Participants: 1
Project status: SIGNED

Caphenia addresses critical environmental challenges by significantly reducing greenhouse gas emissions in industries such as aviation and heavy manufacturing. These sectors are heavily dependent on fossil fuels, leading to substantial CO2 emissions, with aviation alone contributing 2-3% of global emissions. The urgency for change is underscored by extreme weather events, rising sea levels, and the socio-economic impacts of climate change, which the European Environment Agency warns could reduce Europe’s GDP by up to 10% by 2030. Our solution, the Plasma Boudouard Reactor (PBR), is a highly efficient process that converts CO2 into synthetic fuel with an impressive 86% efficiency, far surpassing the 45% efficiency of conventional Power-to-Liquid (PtL) processes. The PBR integrates methane pyrolysis, the Boudouard reaction, and the heterogeneous water-gas shift reaction into a single reactor, utilizing biomethane and biogenic CO2 to produce sustainable aviation fuel (SAF). This innovative process reduces CO2 emissions by up to 92% compared to fossil fuels and operates with less than 50% of the electricity required by existing methods. Caphenia’s technology offers significant benefits, including a drastic reduction of CO2 emissions, cost efficiency with production costs 40-70% lower than many competitors, and compatibility with existing infrastructure, ensuring a seamless transition for industries. Additionally, our process aligns with the European Green Deal, aiming for climate neutrality by 2050, and helps companies avoid regulatory penalties associated with non-compliance with environmental regulations. By utilizing renewable sources, Caphenia ensures a stable and sustainable fuel supply, addressing the critical supply and cost issues faced by the aviation and heavy manufacturing industries.

Keywords: co2 emissions,plasma boudouard reactor pbr,power and biogas to liquid pbtl,sustainable aviation fuel saf
LEADING CYBERSECURITY IN THE GENERATIVE AI ERA (NeuralTrust)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2379517.0
EU funding (EUR): 2379517.0
Participants: 1
Project status: SIGNED

NeuralTrust, founded in 2022, is a pioneering company specializing in cybersecurity for generative AI. As the adoption of generative AI grows rapidly, so do the associated risks, including security vulnerabilities, misinformation, biases, and accessibility issues. Current methods to secure and control generative AI are often ineffective, relying on limited guardrails and outdated benchmarks. NeuralTrust is the world's most advanced cybersecurity platform for generative AI. It is a comprehensive Software-as-a-Service (SaaS) platform that protects companies from all risks associated with this technology, including security, reputational, operational, and regulatory risks. NeuralTrust has trained its own security language models and developed a platform with five interconnected modules: Algorithmic Red Teaming, Secure AI Gateway, Monitors, Traces, and Analytics, providing end-to-end protection for generative AI systems. It also ensures compliance with the EU AI Act and aligns users with the best practices in Responsible AI established by the EU AI Pact. The company's contributions align with broader goals such as the UN Sustainable Development Goals and the EU Cybersecurity Strategy, addressing security vulnerabilities and fostering trust in AI. NeuralTrust's technology is also energy-efficient, operating 70% more efficiently than competitors on equivalent infrastructure. The company is positioned to capitalize on the rapidly expanding generative AI cybersecurity market, projected to grow significantly in the coming years. To achieve this goal, EIC support is crucially needed. In this project, NeuralTrust will complete three key objectives: achieving holistic security, automating the platform for massive deployments, and integrating with cloud providers and distribution channels. This is a strategic technology for Europe, as the AI revolution cannot happen without security and trust. NeuralTrust's ambition is to advance the frontier and become market leaders worldwide

Keywords: generative ai,large language models llms cibersecurity,algorithmic red teaming,secure ai gateway,real time monitoring,eu ai act
Environmental landscape ethics: a theory of cohabitability (COHAB)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Finland
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 1481105.0
EU funding (EUR): 1481105.0
Participants: 1
Project status: SIGNED

This project seeks to establish a new environmental ethics subfield, environmental landscape ethics, and to develop a new theory around the notion of ‘cohabitability’ as a focal analytical framework for it. Because land use for human purposes covers most of Earth’s habitable (ice-free and fertile) land, there is a pressing need to develop ethical theory to address land use. Yet, the present environmental ethics is ill-equipped for addressing land management because it largely builds on the legacy of wilderness orientation that focuses on mitigating human impacts to secure the ‘intactness’ of nature. Thus, new theories, terminology, and methods are needed. COHAB will establish environmental landscape ethics and theory of cohabitability by creating interdisciplinarily constructed, ecology-informed theoretical argumentation, methods, and conceptual tools. Cohabitability, land’s suitability for simultaneous co-habiting by many species, is an anchoring concept that connects the key research questions: • RQ1 What are the theoretical and conceptual requirements for environmental landscape ethics? • RQ2 What does cohabitability mean and what is it made of? • RQ3 What are the normative implications of cohabitability? • RQ4 Who can and should promote cohabitability and how? RQs yield four distinct research perspectives. RQ1 examines in detail the need for environmental landscape ethics and articulates the methodological and conceptual requirements for a sound approach in this subfield. RQ2 develops the conceptual framework for the theory of cohabitability by utilising interdisciplinary theory construction and conceptual development in philosophy. RQ3 examines the normative implications of and creates normative principles for the ethics of cohabitability. RQ4 examines action for cohabitability from both normative and empirical perspectives. Answers to RQs will together yield a theory of cohabitability and contribute to the environmental landscape ethics as a novel field.

Keywords: human environment systems,environmental ethics,landscape ecology,urban planning