Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
REsearchers' Nights organized by Athens area Research Institutions to convey the science benefits to the public and motivate young people to science careers (RENA II)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Greece,Greece,Greece,Greece
Call: European Researchers' Night (H2020-MSCA-NIGHT-2018, 2018)
Start date: 2018-06-01
End date: 2020-01-31
Duration (months): 20.0
Total project cost (EUR): 185000.0
EU funding (EUR): 185000.0
Participants: 7
Project status: CLOSED

A diverse team of experts in scientific research and science communication from leading Research Institutes and Educational Organizations, located in the Athens Metropolitan area and with satellite installations and collaborators all over Greece, is formed to organize the Researcher's Night activities for the years 2018 and 2019. By adopting the concept “Science invites People”, we propose a large scale ReN, in 2018, at NCSR-Demokritos, the largest Science Research campus in Attica and Greece, and a similar event in 2019 at "Hellenic Cosmos" the Cultural Centre of the Foundation of the Hellenic World, an ultra-modern Cultural Centre and Museum that stands out for its innovative programs, organized by the National Observatory of Athens. Based on past experience, we plan activities for an expected attendance of many thousand visitors. Our proposal involves activities from several scientific domains exemplifying in many cases the benefits of Interdisciplinarity. The activities will include the organization of pre-events, as part of the awareness campaign, as well as parallel events in three regions across Greece including Iraklion Crete, Rethymnon Crete, Corinth, Patras, Kalamata and Xanthi, where participating Institutions have satellite installations, so as to maximize impact and reach. The purpose of the project is to convey to the general public the key ideas that Research is a necessary ingredient for progress, the Researchers are an integral part of the community and their profession is both fun, challenging, interesting and worth pursuing. The presentation of the work of the scientists to the Greek public will showcase the importance of scientific and technological breakthroughs leading to inventions and opportunities which benefit society in many ways. The special activities addressed to kids will motivate young people to choose science careers when they grow up.

Keywords: science,progress,society,career,scientist,scientific research
Assessing Sectoral Perspectives on Climate Transitions to support the Global Stocktake and subsequent NDCs (NDC ASPECTS)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Fighting and adapting to climate change
Action type: Research and Innovation actions
Countries involved: Indonesia,South Africa,India,Germany,Spain,Germany,Belgium,Finland,China,Russian Federation,Greece,Greece,France,United States
Call: Scientific support to designing mitigation pathways and policies (H2020-LC-CLA-2020-2, 2020)
Start date: 2021-05-01
End date: 2024-04-30
Duration (months): 36.0
Total project cost (EUR): 4999375.0
EU funding (EUR): 4999375.0
Participants: 15
Project status: SIGNED

The NDC ASPECTS project will provide inputs to the Global Stocktake under the Paris Agreement (PA) and support the potential revision of existing Nationally Determined Contributions (NDCs) of the PA’s parties, as well as development of new NDCs for the post 2030 period. The project will particularly focus on four sectoral systems that are highly relevant in terms of the greenhouse gas emissions they produce yet have thus far made only limited progress in decarbonization. To advance these transformations will require to understand and leverage the Eigenlogic of those systems and take into account specific transformation challenges. These sectors are transport & mobility (land-based transport and international aviation & shipping), emission intensive industries, buildings, and agriculture, forestry & land-use, including their supply by and interaction with the energy conversion sector. For each of those sectors we will undertake „Sectoral Conversation“ to co-create evidence-based narratives with sectoral experts and stakeholders drawing on the consortium’s extensive networks. These narratives can then be translated into global pathways informing the Global Stocktake as well as national pathways for strategically selected countries for each of the four sectors. As an input to the Sectoral Conversations we will systematically assess transformation challenges and opportunities (economic, technological, political/institutional, capacity and awareness), including taking into account experiences with the implementation of the first round of NDCs as well as model-based quantitative analyses. Additionally, we will identify ways and means to improve international governance to enable and facilitate sectoral transformations.

Keywords: sectoral perspective,energy intensive industry,transport and mobility,afolu,buildings,transformation,decarbonization,sectoral pathways
Trustful hyper-linked entities in dynamic networks (reTHINK)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Future Internet: Software, hardware, Infrastructures, technologies and services
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Germany,Spain,Germany,France,France,Portugal,Portugal
Call: Smart Networks and novel Internet Architectures (H2020-ICT-2014-1, 2014)
Start date: 2015-01-01
End date: 2017-06-30
Duration (months): 30.0
Total project cost (EUR): 4720331.25
EU funding (EUR): 4720331.25
Participants: 10
Project status: CLOSED

The Internet (r)evolution has changed traditional business and forces it to reinvent itself. Traditional operator-enabled services are losing on their importance due to a variety of new communication services, like chat and social networks, which complement or supersede traditional ones like voice telephony. Technical progress has minimized the need for access-controlled communication services and is moving instead to context based communication, which is presumably available at only marginal or no additional cost. However, unlike traditional telecommunication services, that enable universal communication, Internet communication tools are characterized by their walled garden approach, where users can only communicate with users of the same application and are not free to change application without losing their data or contacts. The main goal of the reTHINK project is to design and prototype a new, non telecom centric, but Web-centric P2P Service Architecture enabling dynamic trusted relationships among distributed applications called Hyperlinked Entities that support use-cases such as contextual and social communications, M2M/IoT and content oriented services. This project will enable any type of service delivery through specialized end-to-end network quality commitments, powered by specialized P2P and/or Cloud services (delivered as SaaS,PaaS or IaaS). The major structural difference between the operators approach and the web companies is related to a recurring concept in the deployment of ICT solutions: full deperimeterisation of services. Operators today cannot directly compete at a global level because their services are not and cannot be provided outside of the deployed and owned network. The services operators provide are tightly coupled with the network's functionalities and its geographical extension. The work is performed by a consortium of 3 global telecom operators, 2 SMEs, 2 Universities and 2 leading research institutes, coordinated by Eurescom.

Keywords: hyper linked entities,future internet architecture,trustful communications,social trustful networks
Flutter Free FLight Envelope eXpansion for ecOnomical Performance improvement (FLEXOP)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Austria,Germany,Germany,Greece,Hungary,Netherlands,United Kingdom,United Kingdom
Call: Competitiveness of European Aviation through cost efficiency and innovation (H2020-MG-2014_TwoStages, 2014)
Start date: 2015-06-01
End date: 2019-11-30
Duration (months): 54.0
Total project cost (EUR): 6692164.38
EU funding (EUR): 6692163.75
Participants: 11
Project status: CLOSED

The FLEXOP project is about developing multidisciplinary aircraft design capabilities for Europe that will increase competitiveness with emerging markets -particularly in terms of aircraft development costs. A closer coupling of wing aeroelasticity and flight control systems in the design process opens new opportunities to explore previously unviable designs. Common methods and tools across the disciplines also provide a way to rapidly adapt existing designs into derivative aircraft, at a reduced technological risk (e.g. using control to solve a flutter problem discovered during development). The goal will be achieved by: (a) improving efficiency of currently existing wing, by increased span at no excess structural weight, while establishing modifications by aeroelastic tailoring to carry the redesigned derivative wing; (b) developing methods and tools for very accurate flutter modeling and flutter control synthesis, to enable improved flutter management during development, certification, and operation, enabling to fly with the stretched wing at same airspeed as the baseline aircraft; (c) validating the accuracy of developed tools and methods on an affordable experimental platform, followed by a scale-up study, demonstrating the interdisciplinary development cycle. Manufacturers will gain cost efficient methods, tools and demonstrators for enhancing aircraft performance by integrated development of flutter control and aeroelastic tailoring. These inter-disciplinary capabilities will improve the design cycle and the Verification& Validation process of both derivative and new aircraft. Better control of development and certification costs can be achieved if these capabilities are used to address problems early in the design process. Flight test data will be posted on the project website to provide a benchmark for the EU aerospace community. The project’s results will serve as a preliminary outlining of certification standards for future EU flexible transport aircraft.

Keywords: flutter,aeroservoelastic control,aerodynamic tailoring
Dissecting Quality Control Mechanisms of Mislocalized Proteins (MisloQC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Germany
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-03-01
End date: 2023-02-28
Duration (months): 60.0
Total project cost (EUR): 1497750.0
EU funding (EUR): 1497750.0
Participants: 1
Project status: CLOSED

Protein quality control systems maintain a functional proteome through detection and removal of abnormal proteins. While typically only misfolded or damaged molecules are thought of as abnormal, recent work has revealed that also mislocalized proteins are subject to quality control. Mislocalized proteins are defined as proteins that fail to reach their native compartment or fail to assemble into their native complex, and thus cannot function normally. Protein mislocalization is a constitutive problem caused by inefficiencies of cellular processes and increases with aging. Proteins can also mislocalize due to mutations, as seen in various metabolic, cardiovascular and neurodegenerative diseases, and some types of cancer. Despite the ubiquity of protein mislocalization, the systems performing quality control of mislocalized proteins are unknown for most of the proteome because quality control substrates are usually rare, thus difficult to identify, and there is considerable redundancy built into quality control systems. Here, I propose to systematically dissect quality control mechanisms of mislocalized proteins through a combination of molecular biology, genetics, biochemistry and computational biology in yeast and human cells. We will establish a platform for conditional protein mislocalization and apply it (i) to identify quality control substrates proteome-wide, (ii) to dissect redundancies in quality control systems, (iii) to identify the machinery responsible for quality control of mislocalized proteins and (iv) to map the features involved in substrate recognition by the quality control machinery. Finally, we will exploit our findings to selectively target aneuploid cancer cells, which exhibit a high burden of mislocalized proteins. This work will provide a comprehensive picture of quality control systems for mislocalized proteins and shed light on their roles under both normal and perturbed conditions.

Keywords: protein quality control,proteome homeostasis,aneuploidy
Brain computer interface to study and manipulate mamories of aversive experience during sleep (MNEMOSYNE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: France
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-10-01
End date: 2023-09-30
Duration (months): 72.0
Total project cost (EUR): 1998250.0
EU funding (EUR): 1998250.0
Participants: 1
Project status: SIGNED

The aim of this project is to study the influence of sleep in the establishment of aversive memory and to propose a proof of concept for the use of brain-computer interfaces during sleep to treat pathologies associated with fear or anxiety such as post-traumatic stress disorders. It is now accepted that sleep plays a crucial role in memory consolidation processes that allow the conversion of newly encoded memory traces into more stable information. Numerous studies have shown that some of the positive effect of sleep on consolidation relies on the reactivations of previous experiences. We recently showed that spontaneous sleep reactivations can be used to create an artificial memory during sleep. We made electrical stimulations of a brain reward center contingent on the spontaneous reactivations of a hippocampal place cell during sleep. After this procedure, mice developed a place preference for the location of the place field of the trigger cell, showing that a place/reward association had been created. Our experiment, as most of the studies on place cells or reactivations, was done with appetitive learning and we now intend to tackle this issue in the context of aversive learning. In this project, we will use our closed-loop device to address long lasting controversies such as the existence of reactivations in deep SWS or REM sleep. We will also investigate how avoided places are represented in the hippocampus and whether they are more reactivated during subsequent sleep. Additionally, we will show whether aversive-related wake preplays can be actively modulated, suggesting that “intrusive memories” or rumination can be addressed in animal models. Finally, we will test whether an aversive association performed during wake can be modified by our closed-loop-driven appetitive association during sleep. This would bring the proof of concept that sleep could be used to erase aversive memories in pathological situations such as post-traumatic stress disorders.

Keywords: close loop,brain computer interface,sleep reactivation,sleep replay
European Agricultural Knowledge and Innovation Systems (AKIS) towards innovation-driven research in Smart Farming Technology (Smart-AKIS)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: Coordination and support actions
Countries involved: Spain,Germany,Germany,Belgium,Serbia,Greece,Greece,France,France,France,France,Netherlands,United Kingdom
Call: Closing the research and innovation divide: the crucial role of innovation support services and knowledge exchange (H2020-ISIB-2015-1, 2015)
Start date: 2016-03-01
End date: 2018-08-31
Duration (months): 30.0
Total project cost (EUR): 1997756.15
EU funding (EUR): 1997731.25
Participants: 16
Project status: CLOSED

Smart-AKIS was submitted to the 2014 call, remaining on the reserve list (12/15). For resubmission, all items in the ESR have been carefully addressed: i) more focused approach, addressing only Smart Farming Technology for crop production and using more concrete methodologies; ii) stronger involvement of the machinery industry, with specific support from national Associations and a dedicated working group within CEMA; iii) a Data Management Plan ensuring compliance with H2020 Open Access Policy and inclusion in different thematic aggregators. The project aims at setting up a self-sustainable Thematic Network on Smart Farming Technology designed for the effective exchange between research, industry, extension and the farming community in order to disseminate direct applicable research and commercial solutions and capture grassroots level needs and innovative ideas. Smart Farming Technology (SFT) encompasses Farm Management Information Systems, Precision Agriculture and Agriculture automation and robotics. Smart AKIS will collect existing knowledge related to SFT and will produce easily accessible end-user material under the EIP-Agri common format. The project will also integrate the socio-economic aspects involved in the innovation processes and will generate interactive and innovation-based collaborations among researchers, advisors and farmers through the use of open innovation in multi-actor workshops. Knowledge flow will be facilitated through the implementation of the Smart Farming Community Platform, which will be compatible with the EIP-SP in order to ensure long term accessibility of results. Smart-AKIS will build on results from five flagship EU projects (VALERIE, SOLINSA, PRO-AKIS, FRACTALS, AGRISPIN), through the participation in the project of their core partners. The project will establish direct communication with EIP-Agri to maximize impact of project activities and stakeholder mobilization.

Keywords: smart farming technology,agricultural knowledge and innovation systems,agriculture,research results,multi actor open innovation,interactive dissemination
A range-wide transplant experiment using participatory science and genomic prediction to assess local adaptation in forest trees (MyGardenOfTrees)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Switzerland
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-06-01
End date: 2026-05-31
Duration (months): 60.0
Total project cost (EUR): 1999999.64
EU funding (EUR): 1999999.64
Participants: 1
Project status: SIGNED

How organisms adapt to their environments is the most fundamental question in evolutionary biology and is of utmost importance given climate change threats. Identifying key traits involved in adaptations and understanding how they interact with each other, and with the environment, is a particularly urgent task for foundation and resource-production species, such as forest trees. Existing experiments assessing local adaptation lack scalability and predictability in natural environments, especially at the species range margins. Landscape genomics studies could reveal adaptive loci across environmental gradients, but they are hindered by the assumptions of a neutral model and the highly polygenic nature of most traits. To address these shortcomings, I will conduct a species range-wide transplant experiment using participatory science and genomics to (i) reveal major patterns and drivers of adaptation and (ii) to build a predictive model for selecting optimal seed sources for a given location that accounts for gene-environment interactions and demography. I will develop a participatory network of foresters as well as ordinary citizens, who will establish a large number (>2500) of micro gardens (4 to 36 m2). Seeds source populations of Fagus sylvatica and Abies alba, and their sister species, will be selected from across their ranges. To evaluate plant performance in novel climate conditions, garden locations will also cover locations beyond the species' current distribution range. Early survival and growth traits, which are under the highest selection pressure in trees, will be monitored and analyzed herein. An unprecedented nearly full factorial design transplant data set will be obtained using a genomic prediction (GP) model that exploits the genetic similarity between populations and the environmental similarity between garden locations. Finally, I will implement the GP model for forest managers to aid assisted migration decisions with evoluti

Keywords: local adaptation,forest trees,transplant experiment,participatory science,genomic prediction,phenotypic plasticity,assisted migration,life history traits,biogeography,climate change,regeneration