Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
f-block hydrocarbon interactions: exploration; exploitation (f-ex)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: United Kingdom
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2017-10-01
End date: 2022-09-30
Duration (months): 60.0
Total project cost (EUR): 2456120.0
EU funding (EUR): 2456120.0
Participants: 1
Project status: CLOSED

Understanding, controlling, and predicting the subtle interactions that hydrocarbons form with metals is a major challenge in molecular science, and a key technology enabler in areas such as homogeneous catalysis, drug recognition, polymer properties, and metal recovery. For the f-block, it is important due to the urgent need for clean access to critical elements such as neodymium, and the safe handling of nuclear waste. However, technical challenges of paramagnetism, radiotoxicity, and relativistic effects, make quantifying and exploiting f-block hydrocarbon interactions very hard using traditional methods or calculations alone. We have used organometallic systems to study two types of poorly understood hydrocarbon interactions with f-block metal cations: arene binding which is stronger, yet controversial in terms of its electronic demands, and neutral hydrocarbon C-H bonding which is weaker, yet crucially reaction controlling. f-ex sets out a new way to experimentally measure and define these subtle hydrocarbon interactions. It then exploits the stored electrons in the metal-arene motif as a new method to control these powerful Lewis acidic metals for new hydrocarbon C-element bond formation and inert hydrocarbon C-H bond cleavage, with the ultimate aim of viable, low-energy hydrocarbon functionalisations. Uniquely, we will extend our organometallic work to the more difficult transuranic elements, and exploit high pressure solution (and single crystal) work to enhance and interrogate intermolecular C-H binding. The targets of this combined study now offer high scientific impact by demonstrating fundamental bonding insight and ground-breaking structures and reactions. Unprecedented new insight also derives from incorporating new techniques, e.g. high-pressure solution and single crystal work, and transuranic organometallic chemistry.

Keywords: rare earth,actinide,organometallic,x ray structure,small molecule activation
Shared mobility opporTunities And challenges foR European citieS (STARS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Germany,Germany,Belgium,Sweden,France,United Kingdom
Call: Shifting paradigms: Exploring the dynamics of individual preferences, behaviours and lifestyles influencing travel and mobility choices (H2020-MG-2017-SingleStage-INEA, 2017)
Start date: 2017-10-01
End date: 2020-03-31
Duration (months): 30.0
Total project cost (EUR): 1805665.0
EU funding (EUR): 1805665.0
Participants: 9
Project status: CLOSED

The goal of STARS is to close the gap between the potential benefits of shared vehicle services, with special emphasis on those innovative forms that are enabled by recent technology applications in the transport sector, and their real impacts in terms of congestion mitigation, environmental footprints and social inclusion, that are mediated by both individual preferences and social innovation patterns. STARS will achieve this goal by integrating knowledge, expertise and research methods from transport engineering, environmental psychology and economics, thanks to the unique blend of different competences and kinds of organisation within the consortium. The role of car sharing in improving mobility in European urban areas and providing new business opportunities to the automotive sector will be assessed through an integrated co-modality approach, where the impact of car sharing on other travel modes (public transport, active means, private cars) will be quantified. To this effect, both business as usual and rupture mobility scenarios will be studied, the former referring to future projections of actual trends concerning the diffusion of car sharing in EU countries, and the latter to an assessment of its full potential in presence of appropriate policy actions aimed at maximising social benefits. These policy actions will be informed by the definition of a decision support toolkit that will allow the identification of the best strategy to implement a car sharing service (kind of service to promote, rough estimation of the market dimension, accompanying measures for competing travel modes, business opportunities for different economic actors) as a function of the socioeconomic characterisation of the area, of the related mobility lifestyles, of the policy context and of the related Sustainable Urban Mobility Planning measures and priorities. Both guidelines (in the form of what-if scenarios) and practical examples will be provided.

Keywords: car sharing
Macroscopic Behavior of Many-Body Quantum Systems (MaMBoQ)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Mathematics
Panel description: All areas of mathematics, pure and applied, plus mathematical foundations of computer science, mathematical physics and statistics
Countries involved: Germany,Italy
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2019-02-01
End date: 2025-01-31
Duration (months): 72.0
Total project cost (EUR): 982625.0
EU funding (EUR): 943506.25
Participants: 2
Project status: SIGNED

This project is devoted to the analysis of large quantum systems. It is divided in two parts: Part A focuses on the transport properties of interacting lattice models, while Part B concerns the derivation of effective evolution equations for many-body quantum systems. The common theme is the concept of emergent effective theory: simplified models capturing the macroscopic behavior of complex systems. Different systems might share the same effective theory, a phenomenon called universality. A central goal of mathematical physics is to validate these approximations, and to understand the emergence of universality from first principles. Part A: Transport in interacting condensed matter systems. I will study charge and spin transport in 2d systems, such as graphene and topological insulators. These materials attracted enormous interest, because of their remarkable conduction properties. Neglecting many-body interactions, some of these properties can be explained mathematically. In real samples, however, electrons do interact. In order to deal with such complex systems, physicists often rely on uncontrolled expansions, numerical methods, or formal mappings in exactly solvable models. The goal is to rigorously understand the effect of many-body interactions, and to explain the emergence of universality. Part B: Effective dynamics of interacting fermionic systems. I will work on the derivation of effective theories for interacting fermions, in suitable scaling regimes. In the last 18 years, there has been great progress on the rigorous validity of celebrated effective models, e.g. Hartree and Gross-Pitaevskii theory. A lot is known for interacting bosons, for the dynamics and for the equilibrium low energy properties. Much less is known for fermions. The goal is fill the gap by proving the validity of some well-known fermionic effective theories, such as Hartree-Fock and BCS theory in the mean-field scaling, and the quantum Boltzmann equation in the kinetic scaling.

Keywords: many body quantum mechanics,interacting quantum lattice models,effective evolution equations,quantum transport theory,renormalization group,topological insulators,universality
Power to the LHC data: an ASYmptotically MOdel-independent measurement of the W boson mass (ASYMOW)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Italy,Italy
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-11-01
End date: 2026-10-31
Duration (months): 60.0
Total project cost (EUR): 1683750.0
EU funding (EUR): 936250.0
Participants: 3
Project status: SIGNED

Despite its success in describing the sub-nuclear realm, the Standard Model of particle and field interactions cannot account for a number of experimental facts that constitute evidence of new and unknown physics. Sitting at both the energy and intensity frontier, the LHC grants the highest chances for solving the current puzzle. By exploiting the data collected by the CMS experiment at the LHC, ASYMOW aims at attaining an unprecedented experimental accuracy on a fundamental parameter of Nature: the mass of the W boson. As of today, there is a tension between the Standard Model expectation and the measured value of the W boson mass. A new measurement with a 10 MeV uncertainty, i.e. twice as small as the single best measurement, is a breakthrough: it could either rule out the tension or build a convincing case that this anomaly is real, thus implying the existence of new physics. The collider physics community has been pursuing this goal for decades. The quest now seems to have hit the wall of systematic uncertainty. This project proposes a new approach towards the W boson mass measurement, which will circumvent the systematic uncertainties that are currently limiting the precision. The novelty of the proposed method lies in its agnosticism with respect to the microscopic picture of W boson production in hadron collisions. The loss of prior knowledge inherent to this new approach will be asymptotically compensated by the large amount of data available for the measurement, as will be collected at the LHC. ASYMOW will be conducted by a small group of scientists and comes with great experimental and theoretical challenges. The main expected result is the measurement of the W boson mass with a precision better than the state-of-the-art. This may open new scenarios in particle physics.

Keywords: w mass,precision electroweak measurements,standard model
Development of new therapeutic treatments targeting cancer stem cells. (StemTarget)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-04-01
End date: 2023-03-31
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: CLOSED

Acute myeloid leukemia is characterized by the accumulation of transformed immature myeloid cell in bone marrow. The course of the disease is marked by poor prognosis, frequent relapse, and high disease-related mortality. In spite of improvements in its therapy, above 60% of AML patients will eventually succumb to the disease, a fact stressing the need for new therapeutic approaches for remission induction and prevention of relapse. The difficulty in treating AML is thought to arise from a chemoresistant subpopulation of leukemia stem cells (LSCs) that are capable of maintaining and reinitiating the disease. Increasing evidences suggest that classic neurotransmitter receptors such as dopamine receptors (DRs) and serotonin receptors (HTRs) are involved in cancer genesis and maintenance. Indeed, DRs and HTRs are expressed on the surface of LSCs. By killing differentially LSCs while sparing healthy hematopoietic stem cells (HSCs), DR/HTR antagonists could constitute a new therapeutic target for AML, especially for eradication of LSCs.

Keywords: cancer stem cell,serotonin receptors,leukemia,cancer
You can also reduce emissions (uCARe)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Germany,Switzerland,Belgium,Greece,China,Sweden,Sweden,Czechia,Netherlands,Netherlands,United Kingdom
Call: InCo flagship on reduction of transport impact on air quality (H2020-MG-2018-TwoStages, 2018)
Start date: 2019-05-01
End date: 2022-10-31
Duration (months): 42.0
Total project cost (EUR): 2999172.5
EU funding (EUR): 2999172.5
Participants: 14
Project status: CLOSED

Since technology and renewal of the vehicle fleet do not lower the level of pollutant emissions or improving air quality fast enough, uCARe develops specific, simple and effective measures targeted at users to further reduce pollutant emissions. These measures are based on the aggregation of scattered high quality data already collected by the consortium, supplemented with results of additional measurement campaigns, and knowledge on the behavior and underlying motivation of users. uCARe sets the following objectives: - To identify all user-influenced emission aspects (such as driving behavior and component choice) and the reduction potential of these aspects. The reduction potential is determined with an in uCARe developed emission model - A toolset consisting of the emission model as well as measures to reduce emissions. This toolset forms the basis for intervention strategies, in which measures are translated to desired behavior. The tools are made available in such a way that they can easily be used by stakeholders (such as cities and consumer organizations) outside of the project. Through this, anybody can set up local initiatives at limited cost. - The deployment of awareness campaigns and pilot projects via (already committed) stakeholders, tuned towards specific users and their motivation, to show that proposed measures are effective and feasible. - An impact assessment of user-related reduction measures, accompanied with technical evidence and options to improve pollutant emission legislation and policy. uCARe aims to be complete in the coverage of user-related emissions aspects and types of pollutants. By also implementing, monitoring and evaluating proposed measures, uCARe ensures that these are the most effective. When these effective reduction measures are implemented, pollutant emissions reductions for an individual vehicle as high as 50% are envisaged.

Keywords: emission testing,monitoring,sensors,retrofit systems,driver feedback,emission modelling,non regulated pollutants,malfunction detection,traffic and transport,reduction measures
Ecophysiology of membrane lipid remodelling in marine bacteria (EcoLipid)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: United Kingdom
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-04-01
End date: 2023-03-31
Duration (months): 72.0
Total project cost (EUR): 1965113.75
EU funding (EUR): 1965113.75
Participants: 1
Project status: CLOSED

Membrane lipids form the structural basis of all cells. In bacteria Escherichia coli uses predominantly phosphorus-containing lipids (phospholipids) in its cell envelope, including phosphatidylethanolamine and phosphatidylglycerol. However, beyond E. coli a range of lipids are found in bacterial membranes, including phospholipids as well as phosphorus (P)-free lipids such as betaine lipids, ornithine lipids, sulfolipids and glycolipids. In the marine environment, it is well established that P availability significantly affects lipid composition in the phytoplankton, whereby non-P sulfur-containing lipids are used to substitute phospholipids in response to P stress. This remodeling offers a significant competitive advantage for these organisms, allowing them to adapt to oligotrophic environments low in P. Until very recently, abundant marine heterotrophic bacteria were thought to lack the capacity for lipid remodelling in response to P deficiency. However, recent work by myself and others has now demonstrated that lipid remodelling occurs in many ecologically important marine heterotrophs, such as the SAR11 and Roseobacter clades, which are not only numerically abundant in marine waters but also crucial players in the biogeochemical cycling of key elements. However, the ecological and physiological consequences of lipid remodeling, in response to nutrient limitation, remain unknown. This is important because I hypothesize that lipid remodeling has important knock-on effects restricting the ability of marine bacteria to deal with both abiotic and biotic stresses, which has profound consequences for the functioning of major biogeochemical cycles. Here I aim to use a synthesis of molecular biology, microbial physiology, and "omics" approaches to reveal the fitness trade-offs of lipid remodelling in cosmopolitan marine heterotrophic bacteria, providing novel insights into the ecophysiology of lipid remodelling and its consequences for marine nutrient cycling.

Keywords: lipid remodelling,biogeochemical cycles,marine heterotrophic bacteria,roseobacters,sar11,fitness trade off
Low carbon footprint and eco-innovative UV water disinfection (Eco-UV)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Enabling the transition towards a green economy and society through eco-innovation
Action type: Innovation actions
Countries involved: Germany,Germany,Sweden,United Kingdom
Call: First application and market replication (H2020-WATER-2014-two-stage, 2014)
Start date: 2015-06-01
End date: 2018-11-30
Duration (months): 42.0
Total project cost (EUR): 4494948.5
EU funding (EUR): 3949129.0
Participants: 4
Project status: CLOSED

The central objective for Eco-UV is the demonstration and characterisation of an innovative UV lamp and driving electronics technology for chemical-free water treatment and disinfection. The newly implemented technology is a ground-breaking innovation providing up to four times increased lifetime with greatly increased efficiency, the energy consumption reduced by 80%. Thus, this technology provides a lower carbon footprint, much improved energy use and hence greatly reduced lifetime costs. Additionally, the innovative technology will be introduced with a mercury-free configuration, removing the need to handle with this hazardous substance in manufacture and disposal, hence providing a sustainable and eco-innovative technology. The project will prove the lamp technology by demonstration in real applications with full characterisation in terms of long-term stability, ageing effects and dose-response-relationship. Furthermore, the UV lamps are integrated in reactors and the performance of the whole UV system is evaluated at a test centre for drinking water. A new testing protocol for different end-users applications will furthermore be derived, which will be the basis for a future standardised validation of industrial UV applications. The technology will be installed at three demonstration sites for an extended running period. At each, the treatment performance of the UV systems will be evaluated according to the inactivation of micro organisms and the reduction of application specific chemicals, e. g. antibiotics and pesticides. A full Life Cycle evaluation of cost and environmental benefits will be disseminated via EU ETV forums to ensure active uptake of the technology offering by comparing it to traditional UV technology in terms of energy, infrastructure and lifetime costs. The proposed UV technology is addressing the thematic priority areas as outlined in the EIP on Water, especially water reuse, water treatment, water governance and the water-energy nexus.

Keywords: water treatment,disinfection,ultra high efficiency,mercury free,low life cycle costs,demonstration sides,evaluation
Final state interactions in heavy flavour decays (FSI in hadron decays)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-03-18
End date: 2021-03-17
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

The precision study of complex multibody decays of bottom and charm hadrons has unique sensitivity to new fundamental particles and interactions that could give rise to the matter-antimatter asymmetry of the universe, or dark matter. New, vast datasets allow for these studies to be performed with unprecedented experimental precision. However, theoretical uncertainties limit the sensitivity of this approach. The proposed research overcomes this limitation by developing novel theoretical tools to describe multibody hadron decays, and applying them to the latest datasets in a unique collaboration between theory and experiment. In particularly, this research program focus on improving particles strong interaction description in the final states of multibody decays (B-->KKK, B--> Kππ, B-->K*μμ and Bc-->KKπ), including both low-energy two-body full amplitudes, with rescattering and coupled channels; and hight-energy charm mesons as intermediate states of the process.

Keywords: lhcb experiment,final state interactions,heavy meson decays,cp violation,amplitude analyses,hadronic loops,rescattering,chpt,collaboration theory experiment