Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Cellulose Based Photonic Materials (CELLO)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-06-01
End date: 2023-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Improper recycling of plastics leads to their degradation in the environment, resulting in smaller pieces of plastics that are harmful for the life on the planet. Microplastics are also intentionally included in many products as whitening agents, to produce white appearance in many personal care products and contribute to the microplastic pollution. In this proposal, we will provide the industry with viable alternatives to substitute current opacifying agents that follow European regulations. In particular, we will propose the use of cellulose, earth’s most abundant biopolymer which is also bioresorbable. To this end, we will exploit our expertise in photonic architectures to engineer scattering inks from nanocellulosic and seaweed materials. In addition, we will also expand the range of applications of cellulose-derived thin films through an inexpensive and scalable patterning process that provides optical functionality to these membranes. The development of smart paper films with different sensing or anti-reflection functionalities will serve to illustrate the many hidden talents of this biomaterial.
Rethinking work beyond productivism from labour law and its uses (RethinkingWork)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-03-01
End date: 2030-02-28
Duration (months): 60.0
Total project cost (EUR): 1498511.0
EU funding (EUR): 1498511.0
Participants: 1
Project status: SIGNED

Despite the diagnosis that rethinking work beyond productivism is key for ecological transition, research on the future of work is confined to a general and abstract level, and therefore remains inoperative. This ERC aims to elucidate the role that national systems of labour law, which define and organise work, already play, and could play further, in the emancipation of work from productivism. To think about the future of work, we propose to start from present institutions, and uses, of labour law, but which, at the margins of the system, do already deviate from the dominant paradigm of productivism, to then develop, by extrapolation, concrete and plausible trajectories and policy proposals for the future of work. First, we will conduct a large-scale European comparative survey to map ‘deviant’ institutions of labour law that support the development of non-productivist time-spaces, i.e. places and moments dedicated to activities that are not productive in the economic sense of the term because they have little or no economic value. Second, we will investigate, through in-depth case studies, whether individuals develop ‘deviant’ uses of labour law to secure to themselves non-productivist time-spaces, beyond the law. Finally, building on these results, we will elaborate ideal-type trajectories for emancipating work from productivism and develop legal arguments supporting the extension of non-productivist time-spaces supported by labour law based on international, European and comparative law, as well as empirical data collected throughout the project. This ERC has the potential to remedy the current scientific bottlenecks in articulating concrete and grounded policy proposals and trajectories for the future of work. From a societal perspective, it will inform socio-economic players and political decision-makers so that, beyond their growing awareness of the limits of productivism on a finite planet, concrete labour law reforms can be debated and decided upon.

Keywords: labour law ecological transition sustainable welfare states ecological labour law post growth post productivism welfare fraud undeclared work environmental labour studies
Electric Vehicles Point Location Optimisation via Vehicular Communications (EVOLVE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Japan,United Kingdom,Belgium,Finland,Netherlands,Korea, Republic of,United States,Canada
Call: MSCA Staff Exchanges 2021 (HORIZON-MSCA-2021-SE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 464600.0
EU funding (EUR): 423200.0
Participants: 17
Project status: SIGNED

Recent developments in the Electric Vehicles (EV) technologies have made great strides to offer new modes of smart green urban mobility, where EVs are used as the main transportation mode replacing the conventional diesel and petrol powered vehicles. EVs are expected to play a key role in achieving ambitious targets of lowering greenhouse emission in the transportation sector. Given the EV penetration rates and future forecasts, it is essential to develop technologies that tackle charging management of EVs considering a holistic view of charging supply/delivery management for EVs, communication of EVs to the smart grid infrastructure system using 5G and beyond systems, smart grids and big data analytics for EVs optimise smart mobility and enhance the quality of experience for EV users. EVOLVE aims to exploit the scientific excellence and expertise of key academic and industrial players into a joint collaborative effort to design, develop and test various technologies that consider the holistic view of EV charging taking into account the view of technical and business stakeholders. EVOLVE will pursue innovation for advancing the technologies in EV charging ecosystem by orchestrating and managing the underlying networking and computational resources, design innovative algorithms using Artificial Intelligence (AI) and Machine Learning ML), developing communication protocols, prediction and optimising load in smart grids, developing software systems and user interfaces (UIs). EVOLVE aims to transcend analytical models and simulation-based validation and aims to deliver five proof-of-concept (PoC) demonstrations. EVOLVE project will provide a platform to foster a close collaboration between academia and industry partners providing each with a unique experience to create new knowledge, share know-how and skills development.

Keywords: ev charging management,wireless communications,vehicular networks and intelligent transportation systems,smart grids
Driving Rural Innovation through startup Villages across Europe (DRIVE)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Coordination and support actions
Countries involved: Italy,Spain,Finland,Bulgaria,Belgium,Cyprus,Greece,Slovenia,Ireland,France
Call: Circular bioeconomy start-up villages (HORIZON-CL6-2024-CIRCBIO-01, 2024)
Start date: 2025-01-01
End date: 2026-06-30
Duration (months): 18.0
Total project cost (EUR): 942092.86
EU funding (EUR): 832400.0
Participants: 13
Project status: SIGNED

In the EU the bio-based economy drives growth through job creation and innovation by utilizing renewable resources and through alignment with the Circular Economy and bioeconomy. In order to stay competitive, Europe´s industry must become greener, circular and digital through collaboration among companies, Member States, and rural regions in Europe. Within this context, the general objective of DRIVE is to increase the implementation of European local startups, fostering innovative ecosystems for the development of new value-added products, technologies and approaches, via a series of exploitation and trainings actions. Thus, the three pillars of the project, namely: the identification of the needs and project´s users, for instance, at least 2 regional accelerators and incubators will be contacted by the consortium in each of the three roadshows, according to the methodology, to exchange best practices and reinforce SMEs and start-ups participation, the second pillar, the roadshows and the hackathons, and the last one, the mentoring for the development of the technologies, are closely intertwined, as they have been conceived to cooperate in an integrated way, in order to exploit the benefits gained by the work team, meaning boosting the quality of their work and possible results. Therefore, the main outcomes of DRIVE can be summarized in four: to develop a tailored business model at an European level for pitching to investors, to apply for regional initiatives or European financial support instruments, to prepare a pitch presentation and identify investor events and to enroll in further acceleration programs for continued idea deployment and commercialization.
Securing international IP Rights for Food tech Innovation: Prolonging shelf-life of plant-based products (Food Tech Innovation)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Germany
Call: Women TechEU (HORIZON-EIE-2021-SCALEUP-01, 2021)
Start date: 2022-07-01
End date: 2023-06-30
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

DIE FRISCHEMNAUFAKTUR (DFM) is a food tech start-up from Saxony-Anhalt a structural week region in Eastern Germany. The deep tech food start-up was founded by Dr. Jenny Müller in 2017. Our female founder is still full-time operating CEO and leading the company to grow further. DFM specializes in developing ground-breaking food-technology aiming to prolong the shelf-life of plant-based ultra-fresh products like e.g. fresh-cut fruits, salads and drinks. The very short shelf-life of 1-4 days leads to a huge amount of food-waste in private households and retail, as they have to throw away perished products. With its innovation and overall vision of DIE FRISCHEMAUFAKTUR tackles two societal challenges: 1. Reducing and preventing unnecessary food waste and thus efficient use of resources and battling hunger 2. Making healthy eating easy and convenient DFM develops production processes to create products, that last far longer than competitive products. The prolongation of shelf-life can be up to factor 30. E.g. DFM developed a process to make fresh-cut pineapple chunks last up to 6 weeks. For this process patents are filed. The best performing product is: fruit and herb infused water. Adding fruit to water is the most natural way to give water a delicious taste – without added sugars, sweeteners or anything. DFM has developed a patented process that solves the short shelf life and offers infused water with 3 months shelf-life. Two patents for the production process of infused water in Germany were already granted. An International PCT patent was filed. Still, in Q1 2022 DFM has to decide for which countries in the world a patent shall be pursued. For each country significant costs of 3-10 TEUR arise. Covering those costs is extremely difficult for a start-up, still having a valid patent in the most important countries worldwide can offer a big chance, too. A grant from Women TechEU would allow to file patents for China, Japan, India, Brazil, Canada, Mexico etc.

Keywords: patent internationalization,shelf life prolongation,food tech,food and berverages,food waste reduction,ip,biotechnology,microbiology,female founder,female ceo
The Telosome: Deciphering the architecture of the shelterin complex and its network (DARTSin)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 230774.4
EU funding (EUR): 230774.4
Participants: 1
Project status: CLOSED

Telomeres of eukaryotic chromosomes are protected by the shelterin complex. The human shelterin is a six-subunit protein assembly (TRF1, TRF2, TPP1, POT1, TIN2, Rap1). This complex associates with telomeric DNA and prevents the mistaken detection of the telomeres as double strand breaks by the DNA Damage Response (DDR) machinery. Illicit DNA repair at telomeres results in cell cycle arrest and end-to-end chromosomal fusions or other improper recombinations causing genome instability. The abrogation of the shelterin assembly or subunit removal decompacts the telomere and causes DDR accumulation. Defects in the shelterin complex are associated with telomere-related pathologies such as cancer and aging. The supra-structure of the mammalian shelterin complex remains unknown. Therefore, we lack fundamental knowledge regarding its organization and function. The shelterin complex also acts as a signalling hub, recruiting accessory factors that participate in telomere homeostasis and maintenance; and shelterin subunits are subjected to posttranslational modifications (i.e., ubiquitination, phosphorylation, SUMOylation); however, the functional role of these modifications is not fully understood. The overarching aim of this project is to solve the atomic structure of the human shelterin complex by cryo-EM and elucidate the molecular events of telomere biology during the cell cycle combining cellular and proteomic approaches. The outcomes will provide the first structure of the shelterin complex and the shelterin interactome, which will allow to understand defects underlying pathology at molecular level and join this information to physiologic and phenotypic data. This project will have a substantial impact on my career, as new skills in biophysics, structural biology and proteomic techniques on human macromolecular complexes will complement my previous expertise in X-ray crystallography, biophysics, and biochemistry on bacterial and viral proteins.

Keywords: telomere,telosome,shelterin,structural biology,cryo em
Epithelial-mesenchymal crosstalk in the pathology of influenza virus infection (EMC-FLU)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: SIGNED

Influenza virus infects the airway epithelium. The connective tissue underneath the epithelium consists of extracellular matrix (ECM) produced mainly by fibroblasts. Small airway fibrosis, characterized by fibroblast activation and excessive deposition of ECM, is emerging as the key driver of the progression of chronic obstructive pulmonary disease (COPD), a very common and life-threatening lung disease for which no cure exists. Irreversible progression of COPD is often triggered by influenza virus infection. However, causative mechanisms between influenza virus infection and small airway fibrosis have not been explored. In this project, the fellow will infect an advanced co-culture model of patient-derived airway epithelial cells and fibroblasts from the human lung to mimic the microenvironment of the airway. Cellular and molecular profiling of the fibroblasts will be performed by an unbiased approach using integrated and interdisciplinary methods. Especially, a unique mass spectrometry and bioinformatics workflow for deep molecular profiling of the ECM will be combined with state-of-the art single cell RNA-sequence analysis to discover profibrotic readouts. Then, she will use cells from COPD patients to translate the findings to the clinic. Finally, she will establish a host-gene specific knockdown co-culture model to elucidate the role of a specific protein that interacts with the ECM and assess the druggability of this potential target. The fellow is a pathologist from Japan with extensive experience in infection with animal models. Her expertise and knowledge in disease pathology will be integrated with the host's prestigious scientific environment. Establishment of international connections will facilitate her to become an academic leader with a unique and multidisciplinary profile to combat infectious diseases of the lung.

Keywords: epithelial mesenchymal crosstalk,influenza virus,extracellular matrix,fibrosis,fibroblast,chronic obstructive pulmonary disease,airway,co culture,organoid,systems biology
Uncovering the mechanisms behind rapid motor adaptation in the brain using recurrent neural networks (MotorAdapt)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer Science and Informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: United Kingdom
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-05-01
End date: 2030-04-30
Duration (months): 60.0
Total project cost (EUR): 1993474.0
EU funding (EUR): 1993474.0
Participants: 1
Project status: SIGNED

Animals and humans learn some motor skills very slowly: for example, it takes about a year for a baby to learn to walk. In comparison, motor adaptation can be very fast. For example, the first time someone walks on snow, it might take them a little time to get used to the new conditions, but not a whole year. And adaptation depends on previous acquired skillset. Mastering tennis for instance increases how fast squash is learned, but also some “bad habits” from tennis have to be unlearned, and switching to squash for too long can hurt one’s performance in tennis. But how the brain learns different motor skills is still unknown. The main reasons are 1) it is very hard to record single neural activity for the time it takes to learn a new skill, and 2) bottom-up methods from computational neuroscience are very precise for modelling neurons and synapses (i.e., the connections between neurons), but fall short when it comes to learning behaviourally relevant tasks. In contrast, methods from machine learning are becoming increasingly more powerful. My innovative idea is that instead of focusing on skill acquisition, which is slow, I propose to focus on rapid adaptation where recordings during its whole duration is feasible. I propose to use data-driven machine learning methods alongside newly acquired motor datasets to uncover where changes occur in the brain during motor adaptation, which brain regions are involved, which rules govern the changes, and how different motor skills interact. Unravelling the fundamental mechanisms underpinning rapid motor adaptation will equip me with the knowledge necessary to engineer tools that accelerate motor adaptation, particularly for medical applications. 100 million people in the EU alone suffer from a disability including movement disorders. I propose to leverage these tools to accelerate how quickly users can adapt to intracortical Brain-Computer-Interfaces to improve quality of live and increase patient adoption rate.

Keywords: computational neuroscience
Animal Welfare Indicators at the SlaughterHouse (aWISH)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Belgium,Portugal,Netherlands,Germany,Greece,Serbia,France,Denmark,Poland,Spain,Austria
Call: Animal welfare 2.0 (HORIZON-CL6-2021-FARM2FORK-01, 2021)
Start date: 2022-11-01
End date: 2026-10-31
Duration (months): 48.0
Total project cost (EUR): 7999587.5
EU funding (EUR): 7999587.5
Participants: 30
Project status: SIGNED

The objective of aWISH is to develop and offer a cost-efficient solution to evaluate and improve the welfare of meat-producing livestock at a large scale, across Europe. This approach will be developed and evaluated in close collaboration with all actors involved, from primary producers up to policy makers and citizens. At the heart of the aWISH solution is the automated monitoring at the slaughterhouse of complementary animal-based indicators for monitoring welfare on-farm, during (un)loading, transport and slaughter. Besides that, existing or routinely collected data (slaughterhouse data, antibiotics usage, farm data, etc.) and needed technologies on-farm or on-transport to complement the measurements at slaughter will be exploited. Piloting and development activities will be done in 6 broiler chicken and fattening pig production chains across Europe (FR, PL, ES, NL, AT, RS), using a lean multi-actor approach, in order to test and validate the project results. Novel sensor technologies and AI algorithms will be developed, and a feedback tool and interface will allow each actor in the chain to get direct feedback of each batch, visualize trends and benchmark animal welfare outcomes. An Animal Welfare Indicator Catalogue will disseminate all validated indicators and standardized data collection methods. From the pilot data, animal welfare initiatives taken at operator, chain, regional or national level will be assessed alongside their environmental and socio-economic impact at operator and sector level. Next to that, 9 Best Practice Guides will be developed to improve key welfare issues in pigs and broilers, and to help external actors deploy the aWISH technologies and feedback tool. How the feedback loop guides and motivates each party to take actions to improve animal welfare will be tested in a longitudinal study, and the needs, perceptions and barriers of all actors from farm to fork incl. the consumer will be researched to maximize impact of the aWISH results.

Keywords: environmental assessment,social research,economic impact,multi actor