Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Innovative polymers from tomato cutin esters monomers (POLYMATOS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 4
Project status: CLOSED

The production of cutin-based polymers is currently made from acid monomers that result in conventional plastics. These cutin-based plastics do not have the 3D structure of the natural cutin, limiting its application. POLYMATOS project aims to develop an isolation and fractionation integrated high-pressure process to obtain cutin esters monomers from tomato pomace (TP) to be applied as building blocks of innovative biopolymers. The present proposal relates with a novel approach to the production of polyesters by addressing a key challenge in the current biopolymer research: the maintenance of the flexible 3D polymeric structure characteristic of cutin in a cutin-like polyester using ester monomers instead of acid monomers. This approach can efficiently increase hydrophilicity and degradability plus modulate the mechanical, chemical, and biological properties of polyesters. The research will focus on evaluating the process conditions that would achieve cutin yields and highly functionalised building blocks in continuous microreactors. POLYMATOS has a strong multidisciplinary character since it links together biology, biochemistry, chemical engineering, and material science to expand the application of TP to the production of an innovative polyester. The proposed process will be a fundamental contribution to generating an additional revenue stream and reducing residues production in tomato processing. Due to the abundance of cutin, the findings can be extended to other production activities, benefiting the food industry and society. POLYMATOS will allow me to develop my leadership skills through innovation. The project will be carried out by the experienced researcher Dr. Aguiar at the Bioeconomy Research Institute, Universidad de Valladolid, under the mentorship of Prof. Cocero. Two secondments, one at Universidad de Málaga and the other one at CellMat Technologies, will be carried out to strengthen knowledge in polymerisation reactions and polymers characterisation.

Keywords: tomato pomace,cutin,biopolymer,subcritical water,supercritical fluid,hydrolysis,microreactors
Women and navigation in the Pacific: an underwater cultural heritage study (WomenAndOceans)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Spain,Guam,United States
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-08-01
End date: 2027-07-31
Duration (months): 36.0
Total project cost (EUR): 285140.64
EU funding (EUR): 285140.64
Participants: 3
Project status: SIGNED

Using historical maritime archaeological methods, this project will investigate the role of Indigenous women in oceans’ activities in the Pacific Islands in order to highlight the importance of Indigenous women knowledge for environmental security. This study will be aligned with the approach of the Science-Policy Platform of the United Nations of working with indigenous and local knowledge to offer solutions to environmental challenges . Environmental security is concerned with ecological emergencies such as climate change, food security or biodiversity loss and its effects on the security of people and societies. Indigenous peoples in general emphasise the spiritual nature of their relationship with the land or the oceans, which is basic to their existence and to their sustainable use of the oceans . Many Indigenous women have always been providing for their families by diving for pearls, seaweeds, shellfish, sea urchins, lobster, sea cucumber, shellfish, oyster, octopus and abalone for centuries . These women have witnessed coastal erosion, changes in currents, warming of the seas, variation in fishing stocks, naval operations or historical shipwrecks, all essential information for environmental security. For Indigenous communities in the Pacific Islands, the main source of livelihood is the sea and Indigenous women have a history of being the ones diving for food and resources. In addition, throughout the Pacific, women are regarded as original sources of navigation knowledge . Consequently, as custodians and teachers of significant traditional knowledge, Indigenous women bring a unique strength and insight to oceans’ governance. Using the ancestral voyaging knowledge and oceans’ relations of Indigenous communities, this study will contribute with science to the role of Indigenous communities’ knowledge in informing responses to global challenges.

Keywords: historical maritime archaeology,indigenous women,oceans heritage,environmental security,navigation
European City Squared: Computational Social Science Simulation for Democracy (EuropeanCity2)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on Democracy and Governance
Action type: Research and Innovation actions
Countries involved: United Kingdom,Israel,Denmark,United States,Germany,Poland,Bulgaria,Belgium,Czechia,Spain,Switzerland
Call: Computational Social Science approaches in research on democracy (HORIZON-CL2-2024-DEMOCRACY-01, 2024)
Start date: 2025-01-01
End date: 2027-12-31
Duration (months): 36.0
Total project cost (EUR): 2972396.25
EU funding (EUR): 2972396.25
Participants: 18
Project status: SIGNED

In response to the urgent challenges facing modern democracies, the European City Squared project will use real and synthetic data, along with the latest advances in quantum and classical computational social science, to develop an agent-based computer simulation environment that integrates recent advances in science and technology with social choice theory. This interdisciplinary approach, involving leading scientists, city governments, universities, entrepreneurs, and civil society representatives, will explore the effectiveness of various voting mechanisms, with a primary focus on Quadratic Voting. This novel method of voting has potential to enhance public good allocation and foster an emergent and natural altruism, addressing concerns such as polarization and trust in government. Our methodology will be underpinned by a rigorous adherence to data protection standards, ensuring GDPR compliance and the ethical integrity of our research. By employing mathematical models inspired by natural phenomena, we will identify algorithms conducive to robust democratic decision-making. These algorithms will be tested in real-world scenarios, in collaboration with our government partners, particularly the city of Aarhus, Denmark. The project aims to not only provide groundbreaking insights into democratic governance but also to contribute practical tools for enhancing efficiency and participation in democratic processes. If successful, our research promises to offer significant contributions to the fields of political science, computational modeling, and social choice theory, with the potential to bring unprecedented efficiency gains for European democracies.
Solution for stabilization and storage of Biospecimens at Room Temperature. (BIORT)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The field of biomedical research and personalized medicine is experiencing a growing dependence on high-quality data obtained from biological specimens. Current storage methods heavily rely on ultra-low temperature freezers which are neither reliable nor sustainable. 300K Solutions introduces a groundbreaking freeze-drying technology for biospecimen storage, overcoming the limitations of existing methods. 300K addresses these challenges by introducing a comprehensive solution, including pre-loaded biospecimen containers, a specially designed freeze-dryer with an innovative heat exchange module, and hermetic storage boxes. This approach ensures reproducibility, traceability, and controlled storage conditions for the target market, Biobanking, as well as for niche markets, Next Generation Sequency and Flow Cytometry.

Keywords: biological samples,stabilization,storage,ngs,flow cytometry,tissues,dna,rna,serum,plasma,cells
Proof of concept of affordable and scalable DNA data storage by developing a writing technology based on enzymatic DNA synthesis with a very dense semiconductor integrated circuit (CMOS chip) (HYPERION)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: France
Call: EIC Pathfinder Challenge: DNA-based digital data storage (HORIZON-EIC-2022-PATHFINDERCHALLENGES-01, 2022)
Start date: 2023-09-01
End date: 2027-08-31
Duration (months): 48.0
Total project cost (EUR): 5082663.75
EU funding (EUR): 4000000.0
Participants: 1
Project status: SUSPENDED

The Hyperion project will prove the concept of affordable, scalable data storage with DNA by developing a world beating writing technology based on the precise, robust control of enzymatic DNA synthesis with a very dense semiconductor integrated circuit. The 4-year research project will further develop a breakthrough approach by the deeptech research-intensive company DNA Script and show that very high-density enzymatic DNA synthesis is feasible. Furthermore, it will demonstrate proof of concept of high-density chip multiplexing, which will be essential to achieve performances commensurate with the best-in-class technologies (>terabyte capacity and MB/s writing speed). In the course of the Hyperion project, we will rely on fabrication and post-fabrication facilities located in the EU. This will contribute to the strengthening of capacity and expertise in line with the European Chips Act. Once the proof of principle is validated, the Hyperion approach will be the basis for deployable storage technologies that can eventually scale into the exabyte regime and beyond with reduced physical footprint, power and cost requirements relative to conventional storage technologies. This Hyperion project will contribute to the EIC Pathfinder Challenge goal by providing a writing solution fit to meet the future needs of a European DNA-based data storage industry. The impacts are expected to be immense on science, society, the environment, and the economy at large.

Keywords: enzymatic dna synthesis,semiconductor,medium density chip,high density chip,dna data storage,sequencing,proof of concept
UNEQUAL EDucation: The Role of Educational Constraints in Shaping Inequalities (UNEQUALED)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: France
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1862332.0
EU funding (EUR): 1862332.0
Participants: 1
Project status: SIGNED

Project UNEQUALED aims to study educational constraints faced by individuals at a stage when they are planning their future investments in human capital. Despite its importance, understanding the determinants of educational choices has been a longstanding challenge for two important reasons. First, it requires broad, representative, data. Secondly, because the environment in which individuals’ educational plans are formed, and adjust, is typically endogenous to their characteristics. I will tackle these issues using large interventions on nationally representative samples of individuals. Different parts of project UNEQUALED target specific questions that will help construct an overall picture. The project will seek to understand, and quantify, the role of the different barriers in leading to unequal learning and opportunities and the effects of easing the constraints. Specifically asking: Can the easing of technological constraints reduce learning inequality? What role does ICT access and training play for distance learning? Does differential social exposure within the classroom impact student outcomes? Can role models help an individual reach their goal? How important are psychological (or socio-emotional) barriers for achievement? I will address each part using detailed micro longitudinal data, but at a macro level (large scale, nationally representative samples). I plan to combine economic concepts with field interventions, experiments and rich econometric and computer sciences tools to analyse big datasets and to causally estimate the impact of the components that drive the adjustment in educational plans, and, ultimately, how these factors into later educational outcomes. All projects will aim to capture the short and long-run impacts. To carry off this ambitious research project, I will work with a large and interdisciplinary network of researchers specializing in economics, statistics, computer science, management science, and public policy.

Keywords: education,inequality,socio economic status,gender,role models,segregation,technology
Plasticity of neurotransmitter release sites in temporal coding, homeostasis, learning and disease (PlasticSite)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Denmark
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2024-01-01
End date: 2028-12-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

Virtually all neural computation relies on synaptic plasticity, the dynamic change of chemical synaptic communication achieved by transmitter exocytosis from vesicles at presynaptic release sites to activate postsynaptic receptors. Plasticity mechanisms must be powerful, scalable and sustainable over all timescales of neural processing. Which part of the synaptic machinery is the best suited plasticity target? The number of synaptic vesicles greatly outnumbers that of release sites, essentially making the sites gatekeepers of all neural communication. Release site plasticity could thus be pivotal to all neural processing. We recently discovered the molecular identity of release sites (conserved Unc13 proteins) and found evidence of potent release site plasticity on timescales of milliseconds, minutes and days. We are now in the position to use this molecular handle to unravel the principles of this plasticity which will be key to understand neural function, behaviour and disease. Owing to the conserved process and machinery, we will harness the power of Drosophila genetics to elucidate general mechanisms and broad relevance of three distinct release-site plasticity phenomena: 1. Release site switching for millisecond facilitation of transmission and its contribution to network pattern generation as needed for locomotion. 2. Release site activation for minutes’ potentiation of transmitter release and its role in homeostasis and learning. 3. Release site accumulation for long-lasting potentiation with regained dynamic range and its role in homeostasis and memory. Finally, disease mutations accumulate in proteins relating to release site function. We will thus (4.) investigate whether these mutations affect release site plasticity in flies and attempt treatment of their induced defects by artificial enhancement of plasticity. My work will set the stage to establish the investigation of the role of this novel and fundamental plasticity in neural function and disease.

Keywords: synaptic transmission,synaptic plasticity,neurotransmitter release sites,drosophila melanogaster
Biologically-inspired Autonomous Systems for Space Exploration (BASE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 199440.96
EU funding (EUR): 199440.96
Participants: 1
Project status: SIGNED

Nowadays, uncrewed spacecraft missions not only push the boundaries of our scientific understanding of the Universe, but are an indispensable tool for monitoring and increasing our understanding of Earth. However, deploying and operating spacecraft comes with many challenges usually not encountered in ground-based systems. Two major challenges are the construction, repair and modification of structures in space (e.g. telescopes like JWST) and their operation under harsh constraints like limited power and transmission bandwidths, restricting especially the computing power available onboard spacecraft. BASE (Biologically-inspired Autonomous Systems for Space Exploration) envisions a future of independent and autonomous spacecraft that can adapt to unexpected situations and reconfigure their structure accordingly without human guidance. To achieve this bold goal, this action will lay the conceptual foundation for such innovative technologies by developing novel concepts combining techniques from AI, neuromorphic computing and mathematics. More specifically, I will (i) for the first time thoroughly analyze the potential benefits (i.e. energy demands, performance) of spiking neural networks to enable onboard AI and (ii) develop methods for the autonomous self-assembly and self-modification of space structures from individual components, focussing on scenarios that are compatible with currently envisioned designs. The ambitious applications considered in BASE will drive highly innovative progress in the considered disciplines, e.g., by deriving the first mathematical theory for characterising computational properties of spiking neural networks. By tightly binding theory and algorithms to concrete applications, the transferability of the outcome of this action to impactful technologies is guaranteed. Finally, the objectives of BASE are complementary, providing both the computing platform and methodology for spacecraft autonomy, yielding a highly unique research program.

Keywords: spiking neural networks,neuromorphic computing
Egressibility: a paradigm shift in evacuation research (Egressibility)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Sweden
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-10-01
End date: 2030-09-30
Duration (months): 60.0
Total project cost (EUR): 1999499.0
EU funding (EUR): 1999499.0
Participants: 1
Project status: SIGNED

The Egressibility project aims at a paradigm shift in the field of building evacuation research by addressing the critical need for inclusive emergency evacuation. While accessibility and universal design have contributed to significant developments in creating inclusive built environments, this research will transform current evacuation design into universally accessible evacuation design, particularly focusing on vulnerable groups such as older populations and people with disabilities. This project is a timely initiative, aiming at shifting the field of evacuation to Egressibility by establishing a scientific discipline dedicated to the safety and security of every person during emergency evacuation, aligning with the broader goals of creating a resilient and inclusive built environment in Europe and beyond. With natural hazards becoming more frequent and more severe due to climate change, ageing populations and geopolitical uncertainties threatening European security, the demand for efficient and inclusive emergency evacuations has never been more pressing. To date, egress provisions and building design tools are still considering adult healthy populations as starting point. By using qualitative and quantitative methods including virtual reality and inclusive machine learning (following the principles of ethical artificial intelligence), the project addresses equal access to safety for all individuals, irrespective of their functional abilities. Egressibility stands at the intersection of technology and a growing awareness of diversity. The Egressibility project will provide a scientifically rigorous approach allowing a paradigm shift in evacuation research and inform policy making and design. This will enable a future in which technology can be used to ensure an inclusive and safe use of the built environment. Egressibility is not merely an academic pursuit; it is a commitment to a fair and equal society.

Keywords: evacuation egress,emergency,safety exit choice,route choice,pedestrian simulations,crowd modelling,crowd safety,pedestrian safety,people with disabilities,evacuation design
SNLS fund project DARE application (ESR3 AMCL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: MSCA other
Action type: Coordination and support actions
Countries involved: Ireland
Call: HORIZON-MSCA-SNLS-2021-IBA (HORIZON-MSCA-2021-SNLS-IBA, 2021)
Start date: 2021-08-01
End date: 2022-12-31
Duration (months): 17.0
Total project cost (EUR): 18212.5
EU funding (EUR): 18212.5
Participants: 1
Project status: CLOSED

Request of financial support to cover the additional costs that researchers/staff members with disabilities face due to the increased costs of their mobility and/or to ensure necessary assistance by third persons or for adapting their work environment.

Keywords: disability support