Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
European Doctoral Programme for Smart Urban Coastal Sustainability (EU-DOCs for smUCS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: France,Croatia,Cyprus,Ireland,Viet Nam,Italy,Romania,Australia,Finland,Spain,Canada,United States,Greece,Ghana
Call: MSCA COFUND 2023 (HORIZON-MSCA-2023-COFUND-01, 2023)
Start date: 2024-11-01
End date: 2029-10-31
Duration (months): 60.0
Total project cost (EUR): 1713600.0
EU funding (EUR): 1713600.0
Participants: 25
Project status: SIGNED

The EU-DOCS for SmUCS programme is a European doctoral programme designed to train 17 PhD students based on cotutelles between La Rochelle Université (LRUniv) and its partners from the EU-CONEXUS European Alliance and beyond. Based on a challenge-driven approach of research and education, it addresses the societal challenges related to Smart Urban Coastal Sustainability (SmUCS), while strengthening cooperation within our alliance in order to enhance human resources for research and innovation in that area. With 60% of the world’s population living within 100 kilometers of the coast and the “land-sea” interface threatened by climate change and the sea level rise, LRUniv has been leading a consistent strategy of combining its forces in research and education in order to define, understand and address the related challenges. These challenges threaten local economies and quality of life of populations, and may take very different forms, from risks related to the artificialization of shorelines, destruction and pollution of wetlands and biodiversity, vulnerability of coastal towns, massive migratory flows, the impacts of unregulated mass tourism, or energy losses related to ageing constructions and lack of urban policies and risk governance. Such complex and interdependent challenges require interdisciplinary approaches at an international level, getting academic and non-academic actors to work together on sustainable and resilient solutions. Building on the combined strengths of its partners, our programme will train a generation of highly skilled researchers through 36-months thesis, able to tackle these issues with comprehensive approaches, a strong international network and a solid training on research-related and transversal skills, leading to their increased employability within academia and beyond after graduation. This programme is anchored in three fundamental principles, PhD Cotutelles, Excellence and interdisciplinarity and Transversal skills.

Keywords: european doctoral programme,cotutelle,interdisciplinarity,career development,coastal ecosystems,environmental risk,governance,zero carbon smart cities,construction,biodiversity,aquaculture,
Autobiographical memory, time and environmental navigation: unveiling the cognitive map of our past through an integrated neuropsychological perspective (ATENA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Compl exity
Panel description: Cognitive science, psychology, linguistics
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1499718.0
EU funding (EUR): 1499718.0
Participants: 1
Project status: SIGNED

Episodic autobiographical memory refers to the ability to recollect and re-experience events of our own life that occurred at a particular time and place. It allows for the development and maintenance of our unique personal identity and self-awareness, namely autonoetic consciousness. An integrated and comprehensive model of how and where episodic autobiographical memories are stored in the human brain is still lacking. The core hypothesis of ATENA is that previous experiences are spatially organized into a cognitive map and that temporal coding indexes the content of such a map. Also, a dynamic re-mapping should occur in the brain, as time passes after the event. Recent theoretical and methodological advances in cognitive neuroscience make the study of episodic autobiographical memory timely. ATENA will integrate cognitive, neuropsychological and neuroimaging approaches to demonstrate that retrieving autobiographical memories crucially relies on spatial and temporal processing. In brief, advanced information-based approaches to neuroimaging (i.e. representation similarity analysis and decoding) will be adopted to directly test the neural representation underlying episodic autobiographical memory and its possible dynamic re-mapping across time. A lifespan developmental study will be designed to test the ontogeny of place and time contribution to episodic autobiographical memory. Finally, the contribution of the alterations in time and place coding in different developmental and acquired neuropsychological conditions characterized by a deficit in episodic autobiographical memory will be tested. Besides a novel integrated neuroscientific account of episodic autobiographical memory and its development across the lifespan, ATENA will open new areas of investigation in the field of the human mind and its complexity and will inspire new approaches for neuropsychological rehabilitation of memory deficits.

Keywords: environmental navigation temporal processing episodic autobiographical memory
Advanced numerical modeling techniques and design of metasurface-based components for 5G communications (BEYOND META)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark,Greece
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-11-01
End date: 2024-10-31
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 2
Project status: CLOSED

The value of the global 5G services market is expected to grow to $249.2 billion by 2026. The considerably increased resources required (i.e. greater spectral bandwidth, greater throughput, lower latency) have already led to the transition of telecommunication channels at higher frequency bands, where the design and utilization of artificially resonant materials, metamaterials, and their two-dimensional equivalents -metasurfaces- has emerged. Metasurfaces, the lightweight, easy-to-fabricate artificial sheet structures composed of subwavelength particles, exhibit unique electromagnetic properties of effectively controlling and manipulating the wave propagation and constitute the enabling technology for the design of mm-wave components. Fully planar waveguiding structures, beam-steerable leaky wave antennas, perfect absorbers are only a few applications of the emerged metasurface concept. Furthermore, increased requirements of multi-Gbps systems have already given a boost to reconfigurable designs of components via electronic tuning of their parameters. BEYOND META will provide a significant contribution to the wireless and mobile telecommunications sector, focused on the field of antennas and propagation, by developing a robust and powerful computational tool for the analysis, design, fabrication and measurement of metasurfaces, as an enabling technology for the production of novel components in the mm-wave region, in order to be incorporated in 5G communications systems, according to the industry demands. Special emphasis will be given on reconfigurability of innovative structures (antennas and absorbers), via application of electronically tunable mechanisms. The realization of these specific objectives will be performed by the researcher at the Section for Electromagnetic Systems of the Technical University of Denmark (DTU), and at Institute of Electronic Structure and Laser (IESL) of Foundation for Research and Technology Hellas (FORTH), at the secondment phase.

Keywords: antennas,metamaterials,metasurfaces,finite element method,periodic structures,mm wave communications,microwave communications
SST & STM system architecture and evolutions. Horizon Europe TOP2 (HE_EUSST_STM_AE_TOP2)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Cluster 4 other
Destination: Other Digital, Industry and Space destinations
Action type: Research and Innovation actions
Countries involved: Austria,Czechia,Germany,Denmark,Finland,France,Greece,Latvia,Netherlands,Poland,Portugal,Romania,Sweden,Italy,Spain
Call: HORIZON-CL4-SSA-SST-STM-AE - SST & STM system architecture and evolutions (HORIZON-CL4-2023-SSA-SST-ART195, 2023)
Start date: 2023-07-01
End date: 2026-06-30
Duration (months): 36.0
Total project cost (EUR): 6000001.25
EU funding (EUR): 6000000.0
Participants: 19
Project status: SIGNED

This Horizon Europe grant is to be understood within a wider context on EUSST, where other grants are being executed simultaneously with the common objective of improving the EU autonomy on Space Surveillance and Tracking. In particular, this TOP focuses on: - Foster European cooperation in the SST domain and improve the EUSST performance towards larger autonomy. - Highlight and propose solutions to fill the gaps in the current EUSST architecture. - Pave the way on which the EUSST system has to evolve towards a higher level of performance (e.g. accuracy; number / size of catalogued objects...), quality of service (e.g. timeliness of information...) and autonomy. - Demonstrate the complementarity, coherence and added-value of each element of EUSST system towards a more autonomous, interoperable SST system. - Explore and look for higher levels of cooperation with other SST systems such as the US SSA system which is of paramount importance to develop long-term cooperation. - Raise the main issues and propose relevant answers to questions posed by all those developments in various technical and operational domains based on the outcome of the previous STM coordination and support actions developed under H2020Insert here text for your proposal. - Propose adaptation to the new changes, and solutions for their possible integration into the existing standards, practices and technological means. The starting point of these activities is the output of 2-3SST2018-20, which constitutes the state of the art on SST matters.

Keywords: eusst,sst,partnership,front desk,services,assets,sensors,radars,telescopes,lasers,catalogue,users,collision avoidance,re entry,fragmentation,survey,tracking,autonomy
GLI-AGE: Role of glial cells in age-related muscle sarcopenia and NMJ-disfunction. (GLI-AGE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-03-01
End date: 2028-02-29
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 1
Project status: SIGNED

Sarcopenia, marked by the progressive loss of muscle mass and strength due to aging, presents a significant public health challenge. Despite its increasing prevalence, treatment options remain limited, focusing primarily on exercise and nutraceuticals. Sarcopenia shares several pathological features with nerve injury-induced muscle atrophy, including neuromuscular junction (NMJ) degeneration. Recent studies have shown that muscle-resident Plp1+ glial cells rapidly activate a neurotrophic program in response to nerve damage. However, despite their established role in nerve regeneration, the involvement of these cells in age-related NMJ loss and muscle atrophy remains largely unexplored. The GLI-AGE project aims to explore the potential involvement of glial cells in age-related sarcopenia. It will utilize HD Spatial Gene Expression technology (HD-ST), a cutting-edge technique that combines advanced sequencing and high-resolution imaging to map glial cell activity and interactions in aged and geriatric mice. The project’s main objectives are: (1) to spatially characterize glial cell networks in aged muscle compared to young muscle, and (2) to validate their regenerative potential by identifying molecular targets (in-vivo and in-vitro) that may be implicated in the progression of sarcopenia. Through its multidisciplinary approach, GLI-AGE seeks to uncover novel therapeutic targets to preserve neuromuscular function and slow muscle degeneration in the elderly. The project’s findings could pave the way for innovative strategies to maintain muscle health, reduce frailty, and enhance the quality of life for older adults, aligning with Horizon Europe’s goal of promoting healthy and active aging.

Keywords: glial cells muscle ageing nmj disfunction sarcopenia hd spatial transcriptomic
International Finance and the Great Powers, 1800-2020 (Great.Power.Finance)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-10-01
End date: 2028-09-30
Duration (months): 60.0
Total project cost (EUR): 1997244.0
EU funding (EUR): 1997244.0
Participants: 1
Project status: SIGNED

The world is entering a new era of great power rivalry, with the rise of China and the Russia-Ukraine war being only the most visible signs. This proposal asks: What are the implications of these developments for global finance? Will China’s rise accelerate financial globalization or rather reverse it? What do the growing tensions between great powers imply for financial markets around the world? And what motivates China to invest trillions of dollars of state funds into its Belt and Road Initiative (BRI)? It is difficult to answer these questions, because major shifts in the international order occur only every few generations. We therefore need to look back, but existing research in international finance mostly relies on evidence since the 1970s – from an era dominated by the US and in which states had limited influence on capital flows. As a result, our knowledge on the role of state power in global finance is limited. More generally, the literature on geopolitics and international economics is still in its infancy. With this proposal, I want to fill these gaps. I use theory, rigorous empirical methods, and comprehensive new data to study how the rise and fall of great powers (or geopolitics) shaped global investments over the past 200 years. In part one, I embark on a major data gathering effort on North-South capital flows and investor returns at a micro-level, covering tens of thousands of individual bonds, stocks, and infrastructure projects since 1800. In part two, I use this comprehensive new data to analyse: (1) how changes in the international balance of power influence the global allocation of capital; (2) how geopolitical shocks such as wars affect investor returns in the short and long run; and (3) whether and how rising powers use infrastructure investments as a strategic tool to extend influence abroad, in particular to advance their energy security, access to scarce raw materials, and for military control.

Keywords: international capital flows,cross border investments,geopolitics,international political economy
Women’s substantive representation and gender mainstreaming in the EU pandemic recovery (RECOVER-GEU)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 164950.08
EU funding (EUR): 164950.08
Participants: 1
Project status: SIGNED

RECOVER-GEU presents an innovative gendered perspective on EU crisis politics and policies integrating theoretical and methodological approaches from political economy, EU, gender and policy analysis. The project aims to understand how the effectiveness of gender mainstreaming within the multilevel governance framework of the EU is moderated domestically by women’s representation. The project addresses whether women's substantive representation extends beyond parliamentary debates to (fiscal) policy outcomes in the case of the Covid-19 crisis and the National Recovery and Response Plans. RECOVER-GEU provides a timely gendered assessment of the ongoing flagship EU response to the pandemic and offers insights into the drivers of heterogeneous gender mainstreaming in the recovery, enriching the debate on the future of EU economic governance and gender equality policies. The project is methodologically innovative as it improves text-as-data approaches for classifying gender-sensitive policy-relevant content and extends civically engaged research methodologies to the multilevel, multilingual and cross-country context of EU politics and policies. The host institution and supervisor offer the fellow an ideal interdisciplinary and policy-oriented environment at the frontier of research on EU crisis responses and gender equality policies. The fellow will receive training in cutting-edge computational, qualitative and gendered policy methodologies. Additionally, she will gain unparalleled access to practitioners and an extensive network of partner institutions in all fieldwork cities and with renowned gender research centers. At the same time, EUI offers crucial research support and expertise in grant development and project management.

Keywords: gender equality policies,gender mainstreaming,covid 19,recovery policies,rrf,ngeu,nrrps,eu economic governance,substantive representation
Deformable Phase Plates for Adaptive Optics applied to Ophthalmology and Microscopy (DeltaSTAR)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2024-10-01
End date: 2026-09-30
Duration (months): 24.0
Total project cost (EUR): 3082338.9
EU funding (EUR): 2157637.23
Participants: 1
Project status: SIGNED

Adaptive optics (AO) technology is pivotal in modern optics, addressing the critical need for advanced imaging capabilities beyond the limitations of traditional fixed lenses. Traditional methods are inadequate for today's complex imaging requirements, particularly in medical diagnostics, where precise, adaptable imaging is crucial for early disease detection and treatment. Phaseform's innovative Deformable Phase Plates (DPPs) cater to this essential need, offering dynamic, high-resolution imaging solutions that adapt in real-time to changes in the subject or environment, significantly enhancing diagnostic accuracy and potential treatment outcomes. Phaseform, a University of Freiburg spinoff, has transitioned from prototype to advanced product development, securing a strong IP portfolio. The technology’s broad applicability promises substantial market penetration in optical microscopy and ophthalmic diagnostics, sectors poised for growth. Validation by key industry players forecasts a lucrative revenue stream, enhancing Phaseform's market position. The company’s strategic progress is bolstered by the EIC Accelerator project, aiming for commercial scalability and market readiness. This includes performance enhancements, cost reduction strategies, and market engagement plans. EIC funding is crucial, enabling Phaseform to navigate the niche market landscape effectively, avoiding restrictive partnerships that could limit broader market access. Phaseform's DPP technology is set to transform optical imaging, offering significant benefits across healthcare, research, and manufacturing, cementing its status as a leader in high-resolution imaging innovations.

Keywords: adaptive optics,ophthalmology,optics,micro system engineering,high resolution imaging,microscopy
Breaking oncometabolites dynamics for next-generation dendritic cells tumor immunotherapy (REACT-DC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-07-01
End date: 2028-06-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Owing to an increased appreciation of the potential for immunotherapy in neoplasia, much attention has been focuing on a greater understanding of the immune, bidirectional intricacies involving the Tumor MicroEnvironment (TME). Recent work has demonstrated that TME elicits environmental changes, metabolic in nature, in the host’s immune cells, that dampen their ability to REACT against tumors. Manipulating the biology of oncometabolites can strengthen an antitumor immune response as well as circumvent therapy resistance. Here I propose innovative modalities to tackle this problem. The Aryl hydrocarbon Receptor (AhR), best known as the receptor for dioxins, has recently been shown to be one "central node" for communication between host's cells and its ligands, disparate as the nature and source. I have recently found that selective AhR deletion in a subset of antigen presenting cells triggers the rejection of an otherwise progressive fibrosarcoma tumor in vivo. I thus hypothesize that, AhR, expressed in orchestrators of immune responsiveness, represents a key sensor of TME composition, influencing the outcome of an immune reaction against tumors. The main objective of this project is to identify AhR-activating metabolites in TME and disclose their impact on tumor rejection or progression. In parallel, I aim at developing novel advanced strategies, with a high degree of translatability to human cells, to specifically inhibit AhR or AhR-dependent programs in selected APCs. I will combine state-of-the-art technology with new and powerful technologies, including advanced single-cell analysis, promoter gene-editing approaches and computational chemistry. The potential of such a project is very high, because such metabolites may be predictors of immune activation or suppression in TME, and the downstream targets of those immunesuppressive oncometabiltes may represent druggable targets to inhibit tumor escape mechanisms.

Keywords: dendritic cells,tme,oncometabolites,ahr,soft tissue sarcomas