Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Indicators for evaluating international performance in service sectors (INDICSER)

Framework: FP7 — Cooperation
Programme: Socio-economic sciences and Humanities
Destination: Socio-economic and scientific indicators
Action type: Collaborative project
Countries involved: United Kingdom,Netherlands,United Kingdom,Germany,Belgium,Germany,Spain,Hungary
Call:  (FP7-SSH-2009-A, 2009)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 3041081.6
EU funding (EUR): 2349725.0
Participants: 8
Project status: CLOSED

The objective of the INDICSER project is to develop indicators which provide information on the performance of service sectors in the EU. At the heart of the project are concerns that such indicators should be valid in terms of concepts, measurement methods and feasibility but should also have value in terms of their usefulness for policy. Therefore the approach adopted is to include both an EU-wide application of existing concepts and develop and experiment with new concepts. This will be carried out within an overall coherent structural framework designed to address the key issues of productivity and value for money. The indicators are divided into two broad areas, market services, whose performance are crucial for raising growth in the EU relative to its competitors, and non-market services, mostly government run, where it is important that tax-payers can assess how far public spending is effective, as well as their contribution to the economy. For market services the project will construct indicators that describe trends in growth and productivity in service sectors and indicators that are useful in analysing determinants of growth, such as innovation, ICT, intangible capital, competitive environment and foreign presence. In view of the global financial crisis, financial services will be covered in greater detail with new output measures developed and applied to a large set of EU countries. For non-market services much of the analysis will focus on indicators for health and education where significant new research is required on both the conceptual framework and practical implementation. Finally the project will also develop experimental indicators which might be useful in the future, covering insurance, collective services, distributive trades and research sector output. The result will be a comprehensive summary on indicators that might be measured, the feasibility of estimation given current data constraints and recommendations that will inform the using communities.

Keywords: service sectors,indicators,productivity
PAradigm SHifts Modelling and INnovative Approaches (PASHMINA)

Framework: FP7 — Cooperation
Programme: Socio-economic sciences and Humanities
Destination: Combining economic, social and environmental objectives in a European perspective
Action type: Collaborative project
Countries involved: Italy,Austria,Czechia,Spain,France,Germany,Austria,Spain,France,Denmark
Call:  (FP7-SSH-2009-A, 2009)
Start date: 2009-11-01
End date: 2012-10-31
Duration (months): 36.0
Total project cost (EUR): 3323673.0
EU funding (EUR): 2607193.0
Participants: 12
Project status: CLOSED

The project will contribute to the goals of the Call showing that it is possible to better address global changes in a long term time perspective (2030–2050), making a first development of tools – new generations of models and indicators – with enhanced capabilities to take into account the interaction between the economy and the environment, paradigm shifts in the energy-transport-environment nexus and the land-use and territorial functions. The objectives of PASHMINA will include: 1. production of exploratory scenarios (qualitative storylines) of future global change options up to 2030 and 2050, complemented by a quantitative analysis of key development indicators (GDP, well being, etc.) undertaken by means of global long term meta-models (WP1) 2. analysis of the consequences of the paradigm shifts in the energy-transport-environment nexus related to the urban functions: housing, mobility, recreation, etc. (WP2) 3. analysis of the possible paradigm shifts in the land use and territorial functions related to agriculture, forestry and more in general ecosystem services: e.g. biofuels, biodiversity, ecosystems metabolism, etc. (WP3) 4. first development a new generation of global indicators and models, starting from already existing sustainability accounting and general equilibrium modelling frameworks and adapting these to make them (more) sensitive to paradigm shifts in the long-term perspective (WP4) 5. pilot assessment of possible adaptation and mitigation strategies to tackle with different paradigm shifts, evaluating their trade-offs (WP5). 6. to produce a comparative evaluation of the advancements in modelling tools achieved by PASHMINA, and to disseminate those in the scientific and stakeholders communities by means of innovative dissemination tools (virtual library, wiki-web tools, webGIS application) and other dissemination activities (WP6).
Future evolution of the Greenland ice sheet and associated impacts: Studies with an advanced Earth System model (FUTGREENLANDICE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2011-07-15
End date: 2014-02-10
Duration (months): 24.0
Total project cost (EUR): 178340.8
EU funding (EUR): 178340.8
Participants: 1
Project status: CLOSED

The contribution of the Greenland ice sheet to 21st century sea level rise is highly uncertain. Most estimates in the most recent IPCC report (AR4) were obtained using relatively crude ice sheet models forced with General Circulation Models (GCMs) output, without including important climate feedbacks associated with the changing ice sheets. Within the proposed project, the response of the Greenland ice sheet to anthropogenic greenhouse forcing is explored with the new Community Earth System Model (CESM), from the US, which includes a “higher-order” dynamical ice sheet model bi-directionally coupled to the Atmosphere-Ocean GCM. With this advanced tool, ice sheets are able to modify local and global climate via changes in surface albedo, topography, and freshwater fluxes to the ocean. The higher-order dynamics and the high resolution of the ice sheet component will permit to address some of the outstanding research questions emerging from recent observations of outlet glacier acceleration. The outcome of this project will constitute an important contribution to AR5 and AR6 estimates of future sea level rise. In addition, the proposed mobility will contribute to the ongoing process of including ice sheets as interactive components of European climate models. The applicant has contributed to the release of CESM and is an expert in the coupling of ice sheet models to Atmosphere-Ocean GCMs and the study of ice sheet-climate interactions. The following research questions will be addressed: the magnitude of changes in surface melting of the Greenland ice sheet and associated feedbacks, under a variety of forcing scenarios; the evolution of fast-flowing outlet glaciers, in similar forcing scenarios; and the potential impacts of ice sheet changes on local and global climate. Projections of future climate will be complemented by simulations of the previous interglacial, the Eemian, during which sea level was 3-6 m higher than today.

Keywords: ice sheets,climate change,sea level,earth system modelling
Negotiating local and global requirements in biomedical research; the case of biobanking (GLOBLOC BIOBANKS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2012-03-01
End date: 2015-02-28
Duration (months): 36.0
Total project cost (EUR): 228529.6
EU funding (EUR): 228529.6
Participants: 1
Project status: CLOSED

Biobanks are large scale storages of human tissue and data that are attributed a vital role as infrastructure for large scale genetic research. Biobanks can be used optimally if exchange of materials and data would be possible; however, many biobanks are established with local interests in mind and are therefore difficult to coordinate with each other. In this project I will explore how the tension between global and local affects 1. the input of materials and data, 2. the output of research results, diagnostics, etc. and 3. the governance of biobanks through legislation, guidelines, etc. in biobanks in the US, India, Singapore and Europe. I will do this by performing an in-depth qualitative study of teh various projects, using analytical resources from the interdisciplinary field of science and technology studies (STS). Performing such an analysis will contribute to insights into the effects of globalisation on medical reseach and generate new options for policy making in this area. In this project, I will collaborate with two of the foremost scholars in STS. I will spend my outgoing phase with Professor Sheila Jasanoff at Harvard University and my return phase with Professor Wiebe Bijker at Maastricht Unviersity. Researchers at both institutiones have extensive experience in social studies of biomedical research and have adopted globalisation as an important research team. Working at these two institutions will therefore allow me to strengthen my profile in cross-national comparative research on science, technology and society and support me in becoming one of the leading figures in the emerging area of studies of globalisation in STS. Additionally, my fellowship will strengthen the ties between two outstanding research programs in STS and will contribute to prolonged collaboration in the future. Finally, my project can contribute to improved policy making on health and research in the European Union.

Keywords: social sciences science and technology studies,biobanks,globalisation,standardisation,co-production
Hydrogen Incorporation in Subducting Lithosphere after Dehydration Reactions (HISLA-DR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2011-07-11
End date: 2014-07-10
Duration (months): 36.0
Total project cost (EUR): 269710.0
EU funding (EUR): 269710.0
Participants: 1
Project status: CLOSED

Subduction zones play a fundamental role in the deep water cycle making the Earth unique among other terrestrial planets. During subduction dehydration of hydrous minerals produces a fluid phase. A part of this fluid phase will be recycled water back to the Earth’s surface through hydrothermal aqueous fluids or through hydrous arc magmas, whereas another part of the water will be transported to the deep mantle by Nominally Anhydrous Minerals (NAMs) such as olivine, pyroxene and garnet. The partitioning of water between these two processes is crucial for the understanding the deep water cycle which has profound implications for the rheology of the upper and lower mantle. However, the transition from hydrous minerals to NAMs has been very little explored and only rough estimations are available. The main thrusts of the project are (1) to undertake a series of novel experiments with hydrous mantle compositions using high-pressure experimental facilities to constrain the actual water contents that are recycled in NAMs in shallow subduction zones (1.5-5.5 GPa and <900ºC) and (2) compare the products with natural assemblages that underwent extensive dehydration during subduction (through antigorite and chlorite high-pressure breakdown reactions). Additionally this project will investigate the link between mechanisms of deformation and mechanism of hydrogen incorporation in NAMs and how they may affect the rheology of the incoming slab and uppermost mantle. This project will be arrange by assuming two years at Australian National University (outgoing host institution), during which experiments will be performed and natural rocks will be analyzed for trace elements and water contents, and one year at Géosciences Montpellier (Return host institution), where microstructural investigations of natural samples will be carried out.

Keywords: petrology,subduction zones,nominally anhydrous minerals,high-pressure experiments,hydrous peridotite,dehydration reactions,trace elements,microstucture,deformation,ebsd
RNA-codified release of cytotoxic peptides from PNA prodrugs as a new therapeutic approach to cancer (MOLECULARDOCTORS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-04-01
End date: 2013-03-31
Duration (months): 24.0
Total project cost (EUR): 163242.4
EU funding (EUR): 163242.4
Participants: 1
Project status: CLOSED

In this proposal we intend to develop a new medicinal chemistry concept base on cell-personalized delivery of tailored drugs. Relying on basic chemical tools such as proximity-induced acyl transfer reactions and catalytic turnover- we will use RNA biomarkers of cancer cells to trigger the specific expression of cytotoxic drugs. This approach, in addition to contribute to basic science in chemistry and chemical and cell biology and suggest new therapeutic strategies, might allow to overcome the most important observed complications in cancer treatment: selectivity and resistance.

Keywords: organic chemistry,biochemistry,chemical biology,tailored medicine,gene expression,therapeutic peptides,nucleic acids,health sciences
Ecological and Genomic Approaches to Speciation in Island Birds (BIRDISLAND)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-04-01
End date: 2013-03-31
Duration (months): 24.0
Total project cost (EUR): 200549.6
EU funding (EUR): 200549.6
Participants: 1
Project status: CLOSED

Although research into the origin of species has made huge progress recently, virtually nothing is known regarding the drivers of speciation at a genomic level. However, the ongoing genomic revolution has made it possible to address key questions such as how many genes are involved in ecological speciation, and whether the same genes are involved in parallel speciation events. Allying Phillimore’s experience in evolutionary ecology of birds and Savolainen’s expertise and significant resources in speciation genomics, we propose to address these outstanding questions. With special emphasis on island finches and Neotropical tanagers, the fellow will conduct a series of global ecological and genomic analyses, combining phylogenies, ecological datasets, candidate genes approaches and novel comparative genomic analyses using the genomes of chicken and zebra finch as templates. He will also disentangle one of the most controversial examples of sympatric speciation in birds, that is, the finches from Tristan de Cunha.

Keywords: speciation,genomics,phylogeny,evolutionary biology,animal ecology
Quantum optics with optomechanical systems (QOOMS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-11-07
End date: 2013-11-06
Duration (months): 24.0
Total project cost (EUR): 185748.0
EU funding (EUR): 185748.0
Participants: 1
Project status: CLOSED

Interferometric measurements are by far the most sensitive displacement measurements , with sensitivities better than 10-20m/sqrt(Hz) either for large-scale gravitational-wave interferometers or table-top interferometers. In these measurements, there are two quantum limits one has to deal with, even after the classical noise has been substantially lowered: quantum phase noise and quantum radiation-pressure noise. The currently operated gravitational-wave interferometers are limited by quantum phase noise at high frequency and the second generation (Advanced Ligo and Advanced Virgo), scheduled for the middle of the decade, will also be limited by quantum-radiation pressure noise at low frequency. Though ubiquitous, such effects are so weak that they have not been experimentally demonstrated yet. The objectives of this project are the followings: -Design and operate an optomechanical resonator where quantum radiation-pressure noise prevails over thermal noise. -Use it in quantum optics experiments: squeezing and quantum non-demolition measurement. -On a longer term, inject squeezed light into a quantum radiation-pressure noise driven interferometer.

Keywords: quantum optics,optomechanics,micro and nanomechanics
Genomics of Ecological Divergence in the fungal species Neurospora discreta (GEDINDIS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2012-01-16
End date: 2015-01-15
Duration (months): 36.0
Total project cost (EUR): 232676.8
EU funding (EUR): 232676.8
Participants: 1
Project status: CLOSED

A central goal in the modern era of evolutionary biology is to understand the genetic basis of adaptation. Microbes are ideal for such work because their genomes are small and maintaining large experimental populations is inexpensive. The difficulty in working with microbes has been identifying adaptive phenotypes beyond simple metabolic traits. The revolution in sequencing technologies make it possible to use a « reverse adaptive genetics » approach where the researcher scans genomes to identify genes with unusual evolutionary histories, identifies environmental parameters consistent with the genes, and finally tests the hypotheses by genetic manipulation. Here, I propose to apply this approach to ecologically differentiated populations of the fungal model species Neurospora discreta PS4B. My project will be based on transcriptome sequencing of populations distributed over a large latitudinal gradient. My work will advance our understanding of the mechanisms of adaptation, and the evolutionary response of organisms to global change. The outgoing phase of the project will take place in the Taylor lab (UC Berkeley), and the return phase in the ESE lab (Univ. Paris Sud). Both host groups have an excellent track record of work on the proposed research topic, and in training young researchers. My existing skills in population genetics and evolutionary ecology will be complemented by state-of-the-art approaches for analyzing genomic data and more classical experiments of molecular genetics. I will benefit from an environment where gathering and interpreting next-generation sequencing data is now routine. I will also increase my communication skills, leadership capacities, scientific network and international visibility. This fellowship will contribute to European excellence by training a researcher capable of integrating complementary approaches to address complex questions of evolutionary ecology, an expertise that is guaranteed to be increasingly valued in the future.

Keywords: population genetics,population genomics,adaptation,ecological speciation,fungi,bioinformatics,model species,gene flow,divergence,selection,genetic drift,neurospora
Role of the Indian Monsoon on Global Climate Change (MONSOON)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2011-07-22
End date: 2013-07-21
Duration (months): 24.0
Total project cost (EUR): 280680.0
EU funding (EUR): 280680.0
Participants: 1
Project status: CLOSED

The monsoon system in the Indian Ocean exerts a strong influence upon the climatic conditions in south and Southeast Asia and the associated monsoon rainfall have great impact on the socio-economic and agriculture development in the densely populated south Asia. Therefore, understanding and predicting the monsoon behavior in response to global change is a high scientific priority. Most of the monsoon reconstructions from the Arabian Sea are based on the upwelling indices, which essentially represent the South West (SW) monsoon wind strength rather than precipitation. A robust indicator of monsoon rainfall is a key requirement to reconstruct monsoon variability. In this regard, Bay of Bengal is a highly suitable region to evaluate the SW monsoon precipitation mainly because four major rivers Irrawaddy, Brahmaputra, Ganges and Godavari discharge annually approximately 1.5x1012m3 of fresh water into the Bay of Bengal. In this context, we propose to exploit marine sediment archives from the Bay of Bengal to reconstruct monsoon rainfall changes on centennial time scale by using very sensitive proxy (salinity) over the last 25-30 kyrs. This will bridge the gap between the instrumental record showing (interannual to decadal variability) and the existing paleoceanographic records (mainly glacial-interglacial to millennial time scales) and use these monsoon reconstructions to explore the teleconnections between monsoon activity and global climate. Ratios of oxygen isotopes and Mg/Ca in planktic foraminifera and quantitative SST estimates based on planktic foraminifer will be used to reconstruct sea surface temperature and salinity changes at century scale. These will be complimented with other surface ocean changes inferred from planktic foraminifer assemblages. These records, in turn, are used to unravel temporal link between monsoon records and other records of low-and high-latitudes climate change.

Keywords: natural sciences,environmental science,marine sciences,geochemistry,climate change,biogeochemical and hydrological cycles