Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Supramolecular Architectures in Microcapsules through Microdroplet Production (SMARTMICROCAPS)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: United Kingdom
Call:  (ERC-2011-PoC, 2011)
Start date: 2012-02-01
End date: 2013-05-31
Duration (months): 16.0
Total project cost (EUR): 163157.7
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The objectives of the SMARTuCAPS proposal is to build upon an unexpected outcome from an ASPiRe project and verify that the idea has both market potential and capacity to be moved towards pre-commercialization. SMARTuCAPS are hollow capsules that are assembled from a highly novel supramolecular building block approach that uses a high-throughput manufacturing platform. SMARTuCAPS overcome the limitations of other microencapsulation technologies by combining simple fabrication and quantitative loading of a wide variety of encapsulated materials with a modular building method that yields tailored products with unparalleled functionality. Preliminary research suggests that SMARTuCAPS have an opportunity to add value within markets that include electronic displays, diagnostics, paints and coatings, oil and gas additives, carbonless paper, textiles, food industry, fragrance, pharma & medicine. The commercialization strategy for SMARTuCAPS is to identify suitable markets that are experiencing strong growth to find companies that may be interested in licensing the technology. Market analysis will combine a preliminary brainstorming workshop and technology development with strategy professionals to identify a broad range of potential applications. The SMARTuCAPS will then be subjected to a more rigorous market study using external consultants to make recommendations on the best markets and the way forward to pre-commercialisation. Technical validation and research will then quantify the physical properties required and further develop the technology towards the identified markets. The project will be managed by a team that is suitably qualified to execute the proposed activities and an external steering committee that is highly experienced in proof of concept projects. The work outlined in the SMARTuCAPS proposal will lead from outputs of the ASPiRe project, investigate the potential market opportunity, and strengthen the technology towards achieving pre-commercialization.

Keywords: 240629
Design of MYB specific inhibitors (MYBIN)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Proof of concept grants
Action type: Support for frontier research (ERC)
Countries involved: Belgium
Call:  (ERC-2011-PoC, 2011)
Start date: 2012-02-01
End date: 2013-01-31
Duration (months): 12.0
Total project cost (EUR): 238000.0
EU funding (EUR): 139100.0
Participants: 1
Project status: CLOSED

During my ERC starting grant project, my lab has identified small molecule inhibitors that inhibit the proliferation of MYB-dependent leukemia cell lines. In this proof of concept project, we aim to investigate the potential of these compounds to be further developed as anti-cancer agents. We will determine their potential to inhibit the proliferation breast cancer and colon cancer cell lines and possible additional activity against other solid tumors. In addition, we will investigate the IP landscape and possibilities to improve the chemical properties. These pre-clinical data should provide the basis for the further development of these MYB inhibitors as anti-cancer agents.

Keywords: 205252
The role of Lgr6 as a marker of progenitor cells and cancer-initiating cells in the mammary gland (LGR6MAMMARYSC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Sweden
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2013-01-01
End date: 2014-12-31
Duration (months): 24.0
Total project cost (EUR): 181418.4
EU funding (EUR): 181418.4
Participants: 1
Project status: CLOSED

The epithelial compartments of the mammary gland are thought to be derived from a tissue stem cell capable of self-renewal and differentiating into all cellular lineages of the mammary gland. Detailed studies of normal and tumorigenic breast stem cells have proven rather cumbersome since these cells are rare and a high degree of purification is needed. Several approaches to isolate mammary stem cells are based on the use of relatively unspecific surface markers, which are also expressed on differentiated cells. Lgr5 is a marker of stem cells in several different organs, such as the intestine, the stomach and the skin. Recently, another Lgr family member, Lgr6, could be identified as a marker of a second epidermal stem cell population in the skin than can regenerate all cellular lineages of the skin. The high homology between Lgr5 and Lgr6 and the fact that both receptors represent stem cell markers in the skin, suggest that Lgr6 could also specifically mark certain stem cell populations in other tissues. Indeed, the host laboratory has found prominent expression of Lgr6 cells in brain, mammary gland and lung. Noteworthy, the hair follicle and the mammary gland are both ectodermal-derived appendages that show strong similarities as regards the molecular mechanisms controlling their formation, maintenance and cellular turn-over. Lgr6 shows a conserved upregulation between human and mouse mammary stem cell fractions. In line with the notion that normal stem cells can be a source of cancer stem cells, breast cancer tissues shows an overexpression of Lgr6, similar to skin cancer cells. The first aim of the proposed project is to clarify the nature and identity of mammary gland cells that express the putative stem cell marker Lgr6. Secondly, this project will determine the functional role of Lgr6 in regard to breast stem cell maintenance, progenitor cell commitment and cancer development.

Keywords: natural sciences,laboratory animal science,molecular biology,mammary gland,stem cell marker,g-protein coupled receptor lgr6,breast cancer stem cells
Aqueous Proton Mobility near Ions and in Nano-Confined Geometries (PERTPROTONDYN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-03-01
End date: 2014-02-28
Duration (months): 24.0
Total project cost (EUR): 191675.4
EU funding (EUR): 191675.4
Participants: 1
Project status: CLOSED

Protons in liquid water posses an anomalously high mobility compared to other ions. This high mobility results from the fact that hydrated protons are not transported as intact units, i.e. by so called mass transport, but rather form defects that diffuse “structurally” through the water hydrogen-bond network. As such, aqueous proton transfer strongly relies on the structure and dynamics of the water network. Many natural and technologically relevant proton transfer reactions occur in the direct presence of ions, proteins or in geometrically confined volumes (e.g. nanopools, nanochannels). We propose to study how the nature and concentration of ionic co-solutes affects the dominant hydration patterns, conversion time-scales and local reactivity of the proton. We will also study how the structuring of the water network in nanopools and nanochannels affects the rate and mechanism of proton transfer. This will be experimentally realized by powerful spectroscopic techniques including femtosecond mid-infrared pump-probe spectroscopy and time-domain terahertz spectroscopy, which are available at the proposed host organization AMOLF (FOM) in Amsterdam, The Netherlands. Compared to conventional linear spectroscopies, these non-linear techniques are ideally suited to discriminate between the large number of sub-ensembles of local hydration patterns of the aqueous proton present in solution. The techniques will allow the measurement of the evolution of these sub-ensembles in time. The researcher, Dr. Ottosson, has a strong background in X-ray spectroscopic investigations of aqueous solutions from his Ph.D. work at Uppsala University, Sweden, making him an ideal candidate for this challenging project. With the guidance of the host scientist, Prof. H.J. Bakker – a world-leading expert in time-resolved studies of water and aqueous solutions – we believe that the chances for success are high.

Keywords: aqueous solutions,proton transfer reactions,strong electrolytes,ion-induced perturbations,confinement effects,nano-pools,nano-channels,femtosecond infrared spectroscopy,thz spectroscopy
Marks of Spectres: Mind, Morality, and Religion in Cultural Discourse (MARKSOFSPECTRES)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-10-01
End date: 2014-09-30
Duration (months): 24.0
Total project cost (EUR): 278807.4
EU funding (EUR): 278807.4
Participants: 1
Project status: CLOSED

My project will expedite my entry into a position of professional maturity by allowing me to engage in a sustained programme of research, training and dissemination activities at the Institute for Cognitive and Evolutionary Anthropology (ICEA), University of Oxford, UK. In the first instance, I will embark on a research programme that uses methods developed in cognitivist approaches to religion to analyse a recurrent topic in literary, intellectual and political discourses––the use of supernatural rhetoric to frame the articulation of moral norms. I will show how all of these ostensibly secular discourses articulate, in coded form, the same innate intuitions that link supernatural agency with the enforcement of moral imperatives in religious discourses. I will pursue this agenda by way of four case studies, which will focus on Indo-European narrative, nineteenth-century fiction, psychoanalytic discourse and European political rhetoric. In addition to my research agenda, I will engage in a series of training activities in my host university. Under the guidance of the scientist-in-charge, Professor Robin Dunbar (Director, ICEA), I will engage in programme of directed reading and research in cognitive anthropology. Supporting this, I will attend graduate courses in cognitive and social-scientific methodologies offered by the ICEA. Also, I will undertake training in developmental psychology and sociology by way of graduate seminars in the Departments of Experimental Psychology and Sociology. Finally, I shall receive complementary skills training in research management from the Oxford Insitute for Learning My project's knowledge deliverables will come in four forms: a monograph in the Macmillan series 'Cognitive Studies in Literature and Performance,' three journal articles (Journal of Indo-European Studies, PMLA, Political Communication), several conference papers, and a major international conference to take place at my host.

Keywords: humanities,social sciences,cognitive science,literary studies,cultural studies,religious studies,anthropology
THOR: Organometallic Thorium Chemistry (THOR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2012-06-01
End date: 2014-05-31
Duration (months): 24.0
Total project cost (EUR): 209033.4
EU funding (EUR): 209033.4
Participants: 1
Project status: CLOSED

Erli Lu is a young multi-award winning scientist of enormous promise and potential and his work is of the highest international quality with publications in top journals. He wishes to build on and apply his formidable array of scientific skills to this ambitious and innovative programme to develop the organometallic chemistry of thorium which is 50 years behind the d-block. Many textbook d-block examples are yet to be achieved for thorium so our fundamental understanding is poor. The PI has extensive experience in actinide chemistry providing a proven method. However, in respect of thorium a more detailed experience of metal-ligand multiple bonds is needed. Thus, the PI has the facilities and actinide expertise, but needs detailed metal-ligand multiple bond input to proceed. Lu brings unique metal-ligand multiple bond expertise but he is unable to progress on his own as he does not have prior actinide expertise. Thus, this Fellowship will exploit the synergy from pairing the PI with Lu and deliver high impact science, future textbook examples, and will further our knowledge of thorium to advance EU science against strong competition from the US in catalysis, magnetism, materials, and energy. This will give invaluable research training and knowledge transfer between Lu, the PI and his group, industry, and other research groups to spread excellence in training and research across the ERA. The PI will move into a new area of research and gain career opportunities. The Host will deliver higher quality research and access new internationally leading frontiers of research. Thorium research will make major step-changes relevant to sustainability and energy priority areas of catalysis and clean energy. The ERA will see a strategically important yet stifled area of research revived and reinvigorated resulting in more competitive EU science that will rival the US which currently leads. A strategic long term collaboration between the ERA and China will be established.

Keywords: thorium,carbene,imide,phosphinidene
Limit Groups over Partially Commutative Groups (LIMITGROUPS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IIF, 2011)
Start date: 2013-02-01
End date: 2015-01-31
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 1
Project status: CLOSED

Klein proposed Group Theory as a means of formulating and understanding geometrical constructions. Geometric Group Theory embraces this approach and also reverses it by using geometrical ideas to give new insights into central problems in Group Theory. In the last decades, it has become a nexus between several branches of mathematics such as Geometry, Model Theory, Dynamical Systems and Algebraic Geometry over Groups. One of the most representative exponents of this interdisciplinary connection is the theory of limit groups. This theory played a crucial role in the recent solution of the famous Tarski problems and revealed a beautiful and deep relation with the theories of JSJ decompositions and very small actions on real trees. As the geometry of free groups is associated to trees, the geometry of partially commutative groups is associated to higher-dimensional analogues of trees. Partially commutative groups are not simply generalisations of free groups, they appear naturally in many different branches of mathematics as well as in computer science, robotics and theoretical physics. This project aims at developing a theory of limit groups over partially commutative groups from algebraic, geometric, algorithmic and model theoretic viewpoints. It intends to explore and strengthen the interconnection between the aforementioned branches of mathematics and to open up directions for further research in each of them.

Keywords: group theory,geometric group theory
Researching Consumer Perceived Ethicality (CPE) of Companies and Brands (RESEARCHING CPE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Germany
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-05-01
End date: 2014-04-30
Duration (months): 24.0
Total project cost (EUR): 174475.2
EU funding (EUR): 174475.2
Participants: 1
Project status: CLOSED

Issues such as corporate social responsibility (CSR) and business ethics have increasingly taken centre stage in today’s society. While researchers agree that consumers react negatively/positively to companies they perceive as un/ethical, the actual question of what evokes such a negative or positive perception has not been investigated. To this day, little is known about how moral equity is generated and emerges in the consumer’s mind. This research shall redress this research imbalance. In order to better understand the link between un/ethical corporate conduct and consumer responses, the question of how ethical perceptions are formed and affected by corporate behaviour is of utmost importance. The planned research hopes to facilitate much-needed theory building and deeper insight into consumer reactions to corporate ethics, CSR, or corporate reputation efforts. Any subsequent research investigating notions of company and brand misconduct, scandal spillover effects, or, more generally, any facets of ethical consumption will benefit from this conceptualisation. The host institution (ESMT) was one of the very first schools in Germany to introduce a chair in Corporate Social Responsibility (held by the scientist in charge) and is therefore an ideal fit with the applicant’s work. With links to the Social Science, specifically Social Psychology, the project will be multi-disciplinary by nature. In addition to the acquisition of new conceptual knowledge, the project promises to considerably expand the applicant’s methodological and analytical skillset. Joining ESMT would allow the applicant to build a strong research network and by so doing enables growth and maturity as a scientific researcher. Given the high relevance of the research topic as well as ESMT’s close ties with the industry sector, the project presented hereafter has strong potential for dissemination among academics and business managers alike, whereby raising the profile of European academic research.

Keywords: corporate social responsibility,corporate ethics,consumer perceptions,ethical consumption behaviour,impression formation,inference processes,social psychology,quantitative research methods
Exact Results in Gauge Theory and Beyond (ERGTB)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2011-IOF, 2011)
Start date: 2013-10-01
End date: 2016-09-30
Duration (months): 36.0
Total project cost (EUR): 268555.2
EU funding (EUR): 268555.2
Participants: 1
Project status: CLOSED

Quantum field theory plays a prominent role in our understanding of many phenomena in physics, from condensed matter physics to particle physics. The standard approach to quantum field theory relies on perturbation theory that is a powerful tool only when the system is weakly coupled and for most of the models, exact results are not accessible. This research project aims at developing and exploiting few of the recently discovered interconnections between gauge theory, string theory, 2D CFT and matrix models, in order to study the strong coupling dynamics of gauge theory and also some formal aspects of string theory. The training proposed in this project aims at improving the candidate's capability to perform leading independent research.

Keywords: ads/cft,agt duality,supersymmetric gauge theory,duality in gauge field theories,strong coupling,matrix models,field theories in lower dimensions,conformal and w symmetry,m-theory.
Consumer Behavior and Energy Taxation: Exploiting Psychological Biases in Designing a Green Tax Reform (ALLEGRO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2011-IOF, 2011)
Start date: 2012-04-01
End date: 2014-03-31
Duration (months): 24.0
Total project cost (EUR): 147505.45
EU funding (EUR): 147505.45
Participants: 1
Project status: CLOSED

Behavioral economics is playing an increasingly prominent role in the formulation of policies to mitigate climate change, including discussions of how to encourage uptake of energy-saving technologies, and how to increase public concern and openness to the types of taxes and transfers that are necessary to have a significant impact on the problem (Allcott and Mullainathan, 2010). But the new analyses of individual behavior coming from behavioral economics have not yet been integrated with more traditional analyses modeling individual responses to economic incentives. The goal of the proposed research is to conduct and estimation of consumer responses to a carbon tax – taking account of insights from behavioral economics. The research will identify how the predicted acceptability of a Green Tax Reform and predicted impacts on behavior depend on the assumptions one makes about the psychology of economic agents. This project will bring together the insights of behavioral economics, in particular with assumptions about the psychology of economic agents, and the rigor of applied demand analysis. Behavioral economics’ theories and techniques represent one of the most powerful and innovative advances in economic research in recent years. Empirical demand analysis, pioneered by Richard Stone, Angus Deaton and John Muellbauer, is one of the most solid, sophisticated, and, from an applicative point of view, effective tools constituting the core of conventional microeconomic theory. While traditional economics and behavioral economics are sometimes seen as intellectual competitors, the two approaches are, in fact, complementary.

Keywords: psychology and economics,carbon taxes,demand analysis,behavioral responses,salience,motivation crowding,behavioral economics
Philosophy for the People? Antonio Brucioli as Translator of Aristotle in Sixteenth- Century Italy (ABRUCIOLI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2011-IEF, 2011)
Start date: 2012-09-01
End date: 2014-08-31
Duration (months): 24.0
Total project cost (EUR): 200371.8
EU funding (EUR): 200371.8
Participants: 1
Project status: CLOSED

My project on Antonio Brucioli (c. 1498-1566) aims to offer the first monograph on his activity as a philosopher and vernacular translator of philosophical texts. A native Florentine, Brucioli was forced to leave his hometown for political reasons and spent the better part of his life in Venice where he devoted his activity to the promotion of the vernacular as a literary language, not only with his famous and controversial version of the Bible, but also with a dozen Aristotelian treatises, until now completely neglected. My monograph will explain the motivations behind this project, Brucioli’s own philosophical ideas, and the intellectual and editorial contexts in which his work unfolded. Combining printed sources with unpublished manuscripts, my book will not be simply a contribution to Brucioli’s biography, but in general to scholarship on the history of ideas in the sixteenth century.

Keywords: aristotelianism,vernacular,latin,printing,venice,florence,history of philosophy,modern history