Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Revivals of Empire – Nostalgia, Amnesia, Tribulation (REVENANT)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Cultures and cultural production
Panel description: Literary studies, cultural studies, study of the arts, philosophy
Countries involved: Croatia
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2022-04-01
End date: 2027-03-31
Duration (months): 60.0
Total project cost (EUR): 1936185.0
EU funding (EUR): 1936185.0
Participants: 1
Project status: SIGNED

The research project REVENANT will examine contemporacollective memories and legacies of the Habsburg, Ottoman, and Romanov Empires from a capacious, comparative perspective. Across the broad geography of central and eastern Europe, the Balkans, central Asia and the Caucasus, and the Middle East, bygone imperial projects are increasingly inseparable from contemporary political and cultural life. REVANANT will constitute the first comprehensive research project to grapple with these complex, overlapping post-imperial memories and legacies. Our overarching research question is: How do collective memories of the Habsburg, Ottoman and Romanov Empires achieve articulation through ensembles of persons, places and things? The threefold heuristic of persons, places, and things determines three secondary research questions. First, how and why do certain historical personages galvanize collective memories of empires? Secondly, how do specific places become sites of post-imperial memory? Thirdly, how are bygone empires embodied through a variety of objects and material culture? The research for REVENANT will be resolutely interdisciplinary, drawing on insights from Anthropology, Sociology, History, Comparative Literature, Art and Architectural History, Memory Studies, and Material Culture Studies. Accordingly, it will rely on a variety of methods, including participant observation, visual ethnography, archival research, targeted interviews with key actors, and discourse analysis. In addition to the principal investigator, the research group will consist of three postdoctoral fellows and three doctoral students. REVENANT will be based at the Cultural Studies Department of the University of Rijeka, Croatia; Rijeka will also be one of the project's research sites. The envisioned results and outputs of REVENANT include a variety of scholarly publications and academic symposia, as well as a documentary film, a photographic exhibition, and a multi-faceted project website.

Keywords: empire,post imperialism,collective memory,space and place,material culture,habsburg,ottoman,romanov
Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders (RUBICON)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: India,South Africa,Australia,Italy,Hong Kong,Netherlands,United States,United Kingdom,United Kingdom,Denmark
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2015, 2015)
Start date: 2016-01-01
End date: 2019-12-31
Duration (months): 48.0
Total project cost (EUR): 877500.0
EU funding (EUR): 607500.0
Participants: 10
Project status: CLOSED

RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious objectives of RUBICON are to increase our knowledge of the mechanisms underlying diverse connective tissue disorders, identify commonalities and targetable pathways, and reinforce multidisciplinary awareness in this fundamental research field. Researchers involved in secondments between RUBICON participants will investigate genetic determinants, circadian clock, extracellular matrix components, soluble biochemical factors and intracellular signalling pathways, ER stress and oxidative components involved in connective tissue homeostasis and pathogenesis. Extensive training during secondments will include new technologies and innovation, study design, interdisciplinary laboratory research, data analysis, research management, ethics in animal and human studies, and development of scientific and communication skills. All participating laboratories will ensure attractive working conditions in excellent and internationally recognised institutions, equipped with state-of-the-art instruments and excellent core facilities. Webinars, courses and meetings will provide additional opportunities for training and networking, also be open to external participants. RUBICON is a unique interdisciplinary network including cell biologists, molecular biologists, animal biologists, morphologists, geneticists, biochemists and clinicians who will cross-fertilise their respective research fields. The long-term goal of RUBICON is to consolidate a class of young scientists to secure future developments in the connective tissue arena and create a solid basis for further collaboration in this field.

Keywords: connective tissues,bone,cartilage,tendon,biomechanics,genetics
Development of Low Cost Cloud Monitoring for the Diagnosis and Prognostic of the Wind Turbines (CLOUD DIAGNOSIS)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Spain
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-2-2015, 2015)
Start date: 2016-06-01
End date: 2018-07-31
Duration (months): 26.0
Total project cost (EUR): 1254470.0
EU funding (EUR): 878129.0
Participants: 1
Project status: CLOSED

Each year, the wind sector is missing out on huge profits due to wind turbines failures of about €200 million in Spain, €700 million in Europe and €2,900 million globally. Taking operation cost into account, losses are actually triple. Adding the currently unfavorable economic situation and policies restricting the sales price, the only way for wind farms operators, maintenance companies, financial institutions, and insurance companies as well as investors to remain profitable is to improve maintenance and operation processes. Smartive is a company whose aim is to develop cloud-based software tools in order to improve the productivity of wind farms. This can be achieved based on newly available technology that allows the detection of anomalous operations by effectively programming preventive and corrective maintenance operations. Diagnosis and prognosis tools will allow adjusting operations and consequently the productivity of wind farms. The overall objective of the Phase II Cloud Diagnosis project is to scale-up our SMARTGEAR technology that allows predictive maintenance to optimize the management and operation of wind parks. Specifically, we will improve the current device by introducing communication protocols allowing extracting data from multiple devices that are placed in wind turbines and by adding transducers. Also, our SMARTCAST cloud diagnosis algorithms need to be improved. These technological improvements will allow us to roll out our solution on a global basis as we will differentiate ourselves from the competition as it will taken into account more data (not only vibration analysis), merge indicators, be cloud based rather than local and be more affordable. Based on our market research, we have forecasted the sales and defined a roadmap for commercialization, including the development of an innovative business model that will allow us to reach all target segments. CloudDiagnosis is of strategic interest to us as the next logical step in our growth.

Keywords: wind turbines,wind energy,artificial intelligence,smart wind monitoring algorithms,vsm cloud computing,condition monitoring system,scada data,cloud computing
Discovery of Immune Therapeutic Targets and Immunomodulators for the Development of Novel Therapies in Rheumatoid Arthritis. (SmallDrugRheuma)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-29
End date: 2020-09-11
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Rheumatoid Arthritis (RA) is an autoimmune chronic disease, characterized by inflammation in multiple joints, ultimately leading to joint deformity, pain and swelling. RA is one of the most frequent inflammatory arthropathies, with a prevalence of 0.3%-1%, striking during the most productive years of adulthood, and is a chronic disabling condition. No therapies exist to prevent RA, and a high percentage of patients do not respond to currently available therapies. Our research aims to integrate expertise on immunology and cutting-edge screening technologies to identify novel immunotherapeutics for RA based on immune modulation mechanisms. The project makes use of an extensive screening effort using a chemical library (60,000 compounds) containing repurposing drugs (drugs already approved for their use for the treatment of other diseases), targeted libraries and lead-like compounds. The aim of the project is to identify novel small molecules capable to modulate the immune response, counterbalancing the altered inflammatory environment that characterizes RA. Elucidation of the mechanism of action of the candidates (cell type, pathway and target) will take place through state-of-the art technologies such as chemoproteomics, RNASeq or CRISPR/Cas9. Ultimately, the most promising candidates will be tested ex vivo in cells from RA patients, providing a proof-of-concept of the therapeutic utility of the identified mechanism. The project is interdisciplinary and will make progress beyond the state of the art, as the identified immunotherapeutics could also be employed to treat other (auto)immune diseases, as well as being potentially translated to immunotherapy of cancer and cardiovascular diseases. The high-quality and originality of this proposal will open up the best career possibilities for the experienced researcher, and will be carried out under the umbrella of a public-private partnership with a pharmaceutical company, boosting European competitiveness.

Keywords: pharmacology,rheumatoid arthritis,autoimmunity,dmards,chemical library,drug discovery,chemoproteomics,immunotherapy,high throughput screening
Coral reef fish shape our understanding of social evolution (SoEvoFish)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United States,United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-08-15
End date: 2023-03-26
Duration (months): 36.0
Total project cost (EUR): 271732.8
EU funding (EUR): 271732.8
Participants: 2
Project status: CLOSED

Complex societies where some individuals forego reproduction, pose an evolutionary conundrum. There have been numerous attempts over past decades to explain why individuals capable of reproduction would give up the chance to propagate their own genes. Yet, there remain debates about the relative importance of various factors in shaping social evolution. Additionally, a clear bias towards the study of terrestrial animals prevents us from viewing the whole picture. The overall objective of the proposed study is to build a more general framework for social evolution in animals, by conducting novel studies of two model coral reef fish systems. Specifically, we will conduct in situ investigations on two species: the clown anemonefish Amphiprion percula (f. Pomacentridae) and the coral goby Paragobiodon xanthosomus (f. Gobiidae). Both species are ideal models as they form groups consisting of a breeding pair and one or several non-breeding subordinates. We will test three hypotheses that explain the social evolution of these species: kin selection, whereby nonbreeders gain fitness benefit by helping close relatives reproduce; ecological and social constraints, whereby non-breeders stay in the group and do not contest for breeding positions because of poor alternative options both outside and inside the group; and synergistic effects, where group augmentation leads to large groups benefiting all members. The project will be conducted at Boston University (BU) and the University of Exeter (UoE), bringing together leading experts of social evolution in fish, Prof Pete Buston, and in mammals and insects, Prof Mike Cant. Thus, the project will promote a two-way transfer of knowledge, and enable us to form a more complete picture of social evolution in the animal kingdom. The proposed work will provide extensive training for the experienced researcher, Dr. Theresa Rueger, and enable her to build on her existing expertise to develop an independent career in research.

Keywords: social evolution,kin selection,group augmentation
A microbial perspective of major historical events in the Southern Cone of the Americas (PaleoMetAmerica)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2020-11-01
End date: 2025-10-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Microbes have played fundamental roles throughout our evolution and history. These roles were not only played by pathogens, but also by the trillions of microorganisms inhabiting our body –the microbiome–, which are essential for homeostasis, physiology, and health. Recent advances in ancient DNA research have made possible to study infectious diseases and human microbiomes from ancient human populations, but this field of research is still at its early stages. For instance, it remains largely unknown which were the microbes (including pathogens) that associated with humans in the past, how they have changed over time, geographic regions and historical events, and to which extent these changes shaped our history and fate. This project will combine state-of-the-art methodologies from phylogenomics, microbiome research, and ancient DNA to bring a new perspective to the study of the human past. This approach will be implemented to investigate major aspects of the history of the Americas, using the Southern Cone as a study-model. First, the microbes (including pathogens) and microbiomes associated with pre-contact Native American populations will be characterized. This reference dataset will be then used to evaluate the impact of the agricultural transition and the European colonization in the oral microbiomes and infectious diseases of these populations. Finally, ancient pathogen genomics will be used to reconstruct the epidemiological scenarios of well-documented post-colonial epidemics. From a technical point of view, this project will also contribute new methods and applications to the emerging field of paleometagenomics. Overall, this work will bring unprecedented evidence to long-lasting debates regarding the impact of the agricultural transition in health and the intercontinental exchange of microbes during the European colonization, add a temporal perspective to the study of human microbiomes and infectious diseases and provide a new framework to study our past.

Keywords: the americas,ancient dna,native american populations,microbial genomics,phylogenomics,infectious diseases,pathogen emergence and spread,oral microbiome,agricultural transition,european colonization,epidemics
DIVERSITY OF LOCAL PIG BREEDS AND PRODUCTION SYSTEMS FOR HIGH QUALITY TRADITIONAL PRODUCTS AND SUSTAINABLE PORK CHAINS (TREASURE)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: Research and Innovation actions
Countries involved: Italy,Spain,Italy,Italy,Italy,Germany,Italy,Spain,Spain,Italy,Italy,Serbia,Croatia,Croatia,Lithuania,Slovenia,Croatia,Lithuania,Slovenia,Slovenia,France,Portugal,Portugal,Portugal
Call: Traditional resources for agricultural diversity and the food chain (H2020-SFS-2014-2, 2014)
Start date: 2015-04-01
End date: 2019-03-31
Duration (months): 48.0
Total project cost (EUR): 3395987.0
EU funding (EUR): 3395986.75
Participants: 37
Project status: CLOSED

Research and development activities are proposed for the benefit of sustainable pork chains based on European local pig breeds and their production systems. Workprogramme is planned to respond to consumer demands for quality and healthiness of pork products with regional identity and societal demands for environment preservation and development of local agro-economy. Description and evaluation of local pig breeds, with an emphasis on untapped ones will be performed using novel genomic tools. Performance of local pig breeds will be evaluated in contrasted agro-geo-climatic conditions and production systems (indoor, outdoor, organic). Focus will be on pig feeding and management strategies and on the use of locally available feeding resources. Intrinsic quality of traditional and new regional high quality pork products and attitudes of consumers from various market areas will be assessed; in particular the motives for the choice and willingness to pay such products. Marketing strategies will be adressed in particular short chain distribution channels. All activities will be driven from the perspective of sustainability (environmental impact, animal welfare, product quality, consumer acceptability and market potential). The activities will engage innovative approaches to answer socio-economic demands of regional pork chains involving partners from different sectors. The ambition is to enhance existing and create new networks between academia and non-academia partners, within and between regions and to tackle the value chain for regional high quality pork products, focusing on diverse and so far untapped pig breeds, their production systems and pork products. Cross-fertilising interactions between research, local agriculture, businesses and end-users will be achieved with partners from these complementary sectors in all research and development activities.

Keywords: traditional meat products,local feed resources,husbandry systems
TADIL and DITEL (TADIL and DITEL)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-06-01
End date: 2016-11-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

TADIL is an ARTIFICIAL INTELLIGENCE software applied to the automatic development of tracings of linear infrastructures. TADIL stands for Techniques for the Automatic Design of New Linear Infrastructures. The currently available modules are targeted at the study of infrastructures of roads and / or highways, (Tadil-Road), and at the study of railway lines, (Tadil-Railway). DITEL, is a complementary software applied to the three-dimensional design of tunnels and linear structures, (viaducts), and bridges. DITEL stands for Intelligent Design of Tunnels and Linear Structures. It is also based on Artificial Intelligence. TADIL allows obtaining in a very fast way the tracing of infrastructure alternatives, providing the definition of the axis in plant and profile according to regulations, the cross sections with its measurement, the earthwork plant, expropriations, the balance sheet of lands, the budget, the public or private feasibility and the subjective evaluation of alternatives. TADIL has been created as a module of Autocad making use of available tools in this software.

Keywords: artificial intelligence,linear infrastructures,highways,roads,railway lines
Constructed wetland to produce high-quality drinking water free from nitrates (ZIRONITRO)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Israel
Call: Boosting the potential of small businesses in the areas of climate action, environment, resource efficiency and raw materials (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-06-01
End date: 2017-08-31
Duration (months): 3.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Three out of four people in EU drink water from groundwater subjected to severe nitrate contamination by fertilizers and sanitary products used in intensive agriculture & farming. High levels of nitrates in drinking water put human health at risk and have been reported to threaten 26% of EU biodiversity. Current technologies do not meet the needs of small water suppliers, who must face costs derived from high energy consumption (3-7 kWh/m3), poor nitrate selectivity, residual streams and by-products, and continuous costly maintenance. 33% of suppliers in Europe are not compliant with quality standards, particularly nitrate levels. ZIRONITRO is the result of 8 years of research and development by Ofra Aqua Plants, an Israeli company with over 25 years’ experience in bioengineering and phytoremediation. Based on the concept of using nature to cleanse nature, ZIRONITRO is a constructed wetland to biologically treat groundwater by removing nitrates to obtain high-quality drinking water (98% removal), at 84% lower cost than current. ZIRONITRO’s innovation resides in the system’s nitrate removal specificity, with a design that allows low-cost operation and maintenance, along with very high rates of nitrate breakdown by bacteria. The key factor is the selection of the best combination of both bacteria and plants, along with the optimal proportion of methanol as carbon source. The particular environment we have generated inside our ponds reduces hydraulic retention time by 90% and uses 100 times less ethanol than current constructed wetlands. Indeed, we do not use synthetic chemicals, energy input needed is negligible, and neither residuals nor wastewater are generated, so it has no negative impact on the environment. On the contrary, it contributes to both biodiversity conservation and landscape value. For 2020-2022, we forecast €61.3 M cumulative revenues (profitability ratio of 12%), increasing workforce to 40 people.

Keywords: water treatment,nitrate,constructed wetlands,drinking water,biological treatment,denitrification