Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Spiking hybrid edge computing for robust optoelectronical signal processing (SpikeHERO)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Germany,Belgium,Netherlands,Czechia
Call: Nanoelectronics for energy-efficient smart edge devices (HORIZON-EIC-2024-PATHFINDERCHALLENGES-01, 2024)
Start date: 2025-10-01
End date: 2029-09-30
Duration (months): 48.0
Total project cost (EUR): 4832490.13
EU funding (EUR): 4229805.54
Participants: 4
Project status: SIGNED

SpikeHERO’s ambitious goal is to design, experimentally realize, and validate a heterogeneous system for low-energy communication and data processing at the edge. It will pursue a holistic approach that maximally leverages a co-design process encompassing both novel integration techniques and the exploration of systems combining electrical and optical chiplets. SpikeHERO will exploit advanced integration technologies, beyond CMOS devices and non-von Neumann architectures in the form of electrical and optical Spiking Neural Networks. When used as a fiber to the edge (FTTE) system to demonstrate a novel optical interconnection, SpikeHERO will significantly reduce the energy consumption from 7-10 W to 1-2 W, while increasing the bandwidth from 10 GHz to 30 GHz. The requirements for SpikeHERO are derived from challenging use cases in the context of smart edge devices as well as inputs from industry partners. The utilized co-design process allows to optimize the overall system performance with regards to the energy efficiency of the entire system. After the overall system is specified and the subsystems are developed and tested, integration can take place through an advanced packaging solution. Besides the advances on the hardware development in SpikeHERO, a digital twin including the optical and electrical Spiking Neural Network is developed. SpikeHERO directly addresses the specific objective of the EIC challenge aimed at reducing energy consumption in smart edge devices by exploring and implementing novel materials, 3D multi-die heterogeneous integration, beyond CMOS devices, and non-von Neumann architectures. The project proposes a unique integration of optical and electrical Spiking Neural Networks that operate conjointly to enhance processing speed and power efficiency, setting a new standard for energy-efficient computing at the edge.

Keywords: 3d multi die integration,optical interconnection,integrated photonics,neuromorphic computing,non von neumann,fiber to the edge,ultra low latency
Nutrient balance and Resource Optimization in Regional Ecosystems through holistic, sustainable, and zero-pollution solution (GREENHOOD)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Clean Environment and zero pollution
Action type: Innovation actions
Countries involved: Spain,Belgium,Netherlands,Finland,Norway,Austria,Italy,Croatia,Greece,Czechia
Call: Demonstrating how regions can operate within safe ecological and regional nitrogen and phosphorus boundaries (HORIZON-CL6-2024-ZEROPOLLUTION-01, 2024)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 9613525.5
EU funding (EUR): 8999483.59
Participants: 32
Project status: SIGNED

The GREENHOOD project pioneers a comprehensive approach to address the global challenge of unbalanced nutrient flows in regional ecosystems. Operating across four European countries and one associated region, GREENHOOD focuses on re-balancing nutrient flows and reducing N/P emissions through five key strategies: a) Participatory Approach: Engaging diverse stakeholders through capacity building, governance labs, and cross-regional exchange activities to ensure inclusive decision-making. b) Estimation of Maximum Allowable Nutrient Inputs: Utilizing optimized budgeting methodologies, including novel modeling tools and socio-economic data, to assess the impacts of new balancing practices. c) Demonstration of Effective Nutrient Management Strategies: Leveraging insights from previous R&D experiences to develop and demonstrate solutions for nutrient excess prevention, reduction, and recycling in key sectors such as agriculture, wastewater treatment, aquaculture, and forestry. d) Establishment of Regional Nutrient Circular Economy Schemes: Creating schemes to close nutrient flow gaps between sectors like livestock-agriculture and aquaculture-agriculture, evaluating the agronomic performance and market uptake of bio-based fertilizers and by-products. e) Innovative Governance Measures: Showcasing governance measures to incentivize the adoption of nutrient-balancing solutions, collaborating with regional administrators and supporting existing policies. GREENHOOD also emphasizes effective dissemination and exploitation of results by collaborating with strategic initiatives like CCRI and Mission projects, as well as conducting regional twinning programs. Through these efforts, GREENHOOD aims to pave the way for societies to operate within safe ecological boundaries while meeting socioeconomic needs.

Keywords: nitrogen,phosphorus,circular economy,nutrient management,nutrient budgets,policy advocacy,nutrient balance
Artificial intelligence-based personalized and interactive radiotherapy target definition for enhanced cancer care (AI-PIONEER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 1832292.0
EU funding (EUR): 1832292.0
Participants: 1
Project status: SIGNED

Cancer is the second leading cause of death globally, with radiotherapy (RT) being a cornerstone treatment for nearly half of all patients. A key element of RT is the accurate definition of target volumes, a task traditionally performed manually by physicians. The quality of target volumes differs significantly between treatment centers and healthcare systems, directly impacting patients’ outcomes. While advances in artificial intelligence (AI) have simplified and standardized the segmentation of healthy organs, creating personalized target volumes that incorporate individual patient-specific data remains an unsolved challenge. AI-PIONEER aims to revolutionize the RT treatment planning process by combining the vast potential of multimodal large language models with 3D image segmentation. For the first time, AI-PIONEER will provide a language-based interface for target volume definition, offering a dynamic and adaptable solution for treatment planning. This will enable the unprecedented opportunity to process both scientific publications and patient-specific data to generate literature-founded, personalized, and precise target volumes. The project has three main objectives: (1) curating an extensive and high-quality multicenter CT dataset, (2) developing and fine-tuning a multimodal foundation AI model for personalized target volume creation, and (3) clinically validating the framework across multiple centers using prospective clinical data, ensuring robust results in real-world settings. By integrating cutting-edge AI technology with clinical expertise, AI-PIONEER will bridge the gaps between efficiency, standardization, and personalization in cancer treatment, ultimately improving patient outcomes worldwide. Thorough clinical validation will provide the basis for clinical translation. This approach is poised to significantly reduce the burden on clinicians while elevating the quality of cancer care.

Keywords: radiation oncology,treatment planning
Energy storage with bulk liquid redox materials (LiquidS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Austria
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-05-01
End date: 2023-10-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The problem: Electrifying transport and storing electricity from renewable intermittent sources is mandatory for a carbon neutral society. Best in class energy density helped Lithium ion batteries (LIB) to now widespread use, giving a taste of the full promise of electrochemical energy storage (EES). However, they rely on scarce elements with associated major cost and energy input for production. Hence, the required giant scale deployment makes no sense ecologically nor economically. Alternative EES devices – supercapacitors and redox flow batteries – each alleviate some of the weaknesses of LIB such as power, used elements, and safety, but remain critically weak in energy per unit weight and mass. Overall, a carbon neutral society has critical demand for environmentally benign EES, which combines the best features of these technologies. Success and troubles of LIBs stem from the used transition metal compounds (e.g., based on Cobalt). Being solid and dense, they allow for high energy, but processes are slow in solids, restricting power. Further, transition metals are scarce, expensive, and energy hungry in production. Therefore, the ideal redox material was based on main group elements, liquid, and had solid-like redox density. The solution: In the ERC StG project OMICON, we discovered such a class of low molecular weight organic redox materials with exciting features: (i) They are liquid in pure form and dissolve salts, being active material and electrolyte at once. (ii) They are reduced and oxidized with a significant voltage difference, hence can act as anode and cathode material. (iii) they are mixed conducting, allowing for very high volume occupation in the electrode. (iv) being liquid, a redox flow battery with unmatched energy density is possible. (v) Consisting of mainly C, O, and H, the materials are accessible in cheap, scalable synthesis from bulk raw materials.
Dynamic Abatement Strategies for maximized environmental and societal health in cities (PUREPOLIS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Climate neutral and smart cities
Destination: Climate neutral and smart cities
Action type: Research and Innovation actions
Countries involved: Germany,Netherlands,Spain,Austria,Belgium,Portugal,Finland,Denmark,France,Poland
Call: Zero-pollution cities (HORIZON-MISS-2024-CIT-01, 2024)
Start date: 2026-01-01
End date: 2028-12-31
Duration (months): 36.0
Total project cost (EUR): 4937520.0
EU funding (EUR): 4937518.0
Participants: 19
Project status: SIGNED

Each year, pollution claims thousands of lives across Europe, yet city administrations struggle with limited resources and the need to balance the multiple and uncertain effects of potential solutions. PUREPOLIS is set to transform urban health by pioneering advanced tools that empower policymakers to take high-impact action. At its core, PUREPOLIS drives data-driven, citizen-powered, and science-backed decision-making. A breakthrough Citizen Science Application (PR1) will enhance engagement and real-time monitoring. The Near Real-Time Pollution Source Apportionment tool (PR2) and Risk-based Health Impact Assessment framework coupling epidemiology and toxicology approaches (PR3) will precisely link exposure to 35 pollutants and their combination across air, noise, water, and soil to 10 critical health risks, including wellbeing. To maximize the efficiency of Zero Pollution Measures, PUREPOLIS will deploy cutting-edge analysis (PR6) to assess their effectiveness in terms of health, economic, and climate impacts, embracing a complexity perspective. These insights will feed into a Dynamic Abatement Strategies Toolbox (PR7), ensuring seamless policy integration into co-created, tailored comprehensive strategy for each of the two case studies in France and Spain, optimising co-benefits with multiple policy sectors. PUREPOLIS also pioneers a Vulnerability framework (PR4) and Behaviour framework (PR5) to drive behavioural changes for more successful interventions and foster equitable and sustainable solutions. Beyond core cities in France and Spain, a next-gen Digital Twin (PR8) and policy reports (PR9) will ensure replicability, scalability, and real-world impact across Europe. With nineteen partners from eight countries over thirty-six months, PUREPOLIS is an unprecedented step forward for healthier, more resilient cities. By fusing science, digital innovation, and citizen-driven action, PUREPOLIS sets a new gold standard for pollution mitigation in Europe.

Keywords: dynamic abatement strategies,zero pollution measures,health impact
Intramitochondrial seeding and sorting of protein aggregates (INTEGRATE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Cell Biology, Development, Stem Cells and R egeneration
Panel description: For all organisms : Structure and function of the cell, cell -cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Italy
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2024-06-01
End date: 2029-05-31
Duration (months): 60.0
Total project cost (EUR): 2499935.0
EU funding (EUR): 2499935.0
Participants: 2
Project status: SIGNED

Quality control processes maintain mitochondrial health, enabling cellular functions such as bioenergetics, metabolism, Ca2+ signaling, and cell death regulation. Mitochondrial proteases, unfolded protein response, asymmetric fission, vesicle shedding, and mitophagy all contribute to organelle quality. However, the specific triggers for these processes remain unclear. While unfolded protein accumulation appears to be a common trigger, the mechanism by which it initiates diverse responses remains uncertain. To investigate this question, we developed advanced tools for real-time imaging of protein aggregation in mitochondrial subcompartments. Aggregates in the matrix and intermembrane space induce mitochondrial fission and elicit distinct functional responses based on their location. Live imaging revealed that intermembrane space aggregates initially seed in the mitochondrial midzone and then sort through transient side-by-side fusion with neighboring mitochondria. In the matrix, aggregates seed at one pole and are selectively sorted to daughter mitochondria through asymmetric fission. Our preliminary experiments unveiled an early seeding and sorting process of protein aggregates according to their intramitochondrial location. In the INTEGRATE project, we aim to comprehensively understand the underlying principles and consequences of this process. By combining advanced imaging techniques, omics analysis, biochemistry, functional assays, and unbiased screenings, we will decipher the rules governing aggregate formation, seeding, sorting, cellular fate, and response in various mitochondrial subcompartments. INTEGRATE seeks to establish the occurrence and downstream responses of this newly discovered early phase of mitochondrial quality control. Clarifying this fundamental mechanism will provide insights into mitochondrial and cell biology, with significant implications for pathological conditions and aging, where mitochondrial quality control is compromised.

Keywords: mitochondria quality control fusion fission
Towards a Kid-Centric, Dynamic and Hybrid Theory of Consumer Socialization to Understand the Dynamics and Implications of the Kidfluencer Phenomenon. (KIDFLUENCER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Belgium
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-09-01
End date: 2030-08-31
Duration (months): 60.0
Total project cost (EUR): 1999830.0
EU funding (EUR): 1999830.0
Participants: 1
Project status: SIGNED

KIDFLUENCER will examine the dynamics of the kidfluencer phenomenon to understand its implications for children’s consumer socialization process. Kidfluencers are generation alpha children (born after 2010) that have highly popular profiles (+ 1.000 subscribers) on social media (e.g., Instagram or YouTube) on which they endorse fun and entertaining content, often containing (sponsored) brand endorsements. Past research merely focused on the negative impacts of kidfluencer activities, such as the commercial exploitation of kidfluencers or the deception of kid followers. This project takes an innovative approach by examining whether kidfluencer activities can be considered as pathways for empowerment and growth contributing to children’s consumer socialization process, while considering potential hazards. Using a three-pronged approach (inspired by cultivation theory), the production, content and impact of kidfluencer activities will be examined, giving a voice to kidfluencers, their entourage and followers. Unique compared to cultivation and consumer socialization research is that children will be considered as active co-creators in the research design, co-deciding upon methodological approaches. By challenging consumer socialization theory’s assumptions of a rational consumer and a linear consumer socialization process, I aim to obtain an in-depth understanding of how children’s consumer socialization process is changing in today’s digital age. A multi-method, longitudinal approach will be adopted, combining quantitative (digital traces netnography, experiments and survey) with qualitative methods (ethnography and expert interviews) to tackle the shortcomings of past research. This comprehensive approach will provide a solid knowledge base on how kidfluencers can be conceptualized as a new, hybrid agent of consumer socialization and whether, to what extent, how and for which children this agent affects young children’s consumer socialization process.

Keywords: social media influencer marketing kidfluencer consumer socialization process cultivation theory entertainment education theory ethnography netnography experimental research survey research
Control and complexity in quantum statistical mechanics (Cocoquest)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Austria
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-06-01
End date: 2027-05-31
Duration (months): 60.0
Total project cost (EUR): 1865833.75
EU funding (EUR): 1865833.75
Participants: 1
Project status: SIGNED

Developing a comprehensive theory of thermodynamics at the quantum scale requires a fundamental change of perspective with regards to its classical counterpart. On the one hand, measuring a quantum system will induce a non-negligible back-action and an energy cost that is at least comparable to the energy scale of the system. On the other hand, controlling microscopic degrees of freedom and harnessing quantum effects provides novel opportunities with no classical counterpart. In light of these facts, control over different quantum features and quantum measurements themselves become valuable resources that need to be integrated into any self-contained theory of quantum thermodynamics. In this project, we aim to address this grand challenge. First we will develop a formal theory that includes control over quantum systems with fixed complexity to incorporate these concepts into thermodynamic considerations at the quantum scale. Second, we will unveil the fundamental thermodynamic limitations on information acquisition by constructing a thermodynamically self-contained description of the quantum measurement process. Finally, we will carefully study current quantum technologies and, with the help of our own lab and experimental colleagues, we will devise experimental proposals and perform proof-of-principle experiments based on existing quantum technologies, to make sure that the theoretical considerations describe relevant features.
Pathways, Ages, Generation in Global North and South (PAGENS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Staff Exchanges
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France,Italy,Madagascar,Togo,Colombia,Burkina Faso,Djibouti,Ethiopia,Canada,Finland,United Kingdom
Call: MSCA Staff Exchanges 2024 (HORIZON-MSCA-2024-SE-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 1761372.86
EU funding (EUR): 1748490.0
Participants: 21
Project status: SIGNED

The PAGENS (Pathways, Ages, Generations in the Global North and South) project is at the forefront of life course research, combining interdisciplinary approaches and international comparisons. It aims to gain a better understanding of how age categories and individual trajectories are shaped by socio-economic, demographic and cultural transformations, in Europe as well as in Africa and South America. The project brings together 22 partners from ten different countries: Colombia, Djibouti, Ethiopia, Madagascar, Burkina Faso, Togo, Canada Finland, France and Italy. A major challenge: redefining the ages of life Facing global changes - population ageing, increasing mobility, job insecurity, climate change - PAGENS proposes an innovative reading of life transitions, incorporating perspectives from the Global South that are often under-represented. Far from standardised models inspired by the North, the project analyses how individuals navigate between ages, statuses and social roles in a variety of contexts. An innovative and inclusive methodology PAGENS brings together a team of researchers in anthropology, sociology, psychology, history, lawyers, literature, and geography, working in synergy with civil society actors and public institutions. Using participatory methods, innovative visual tools (photography, video, mapping) and comparative approaches, the project produces in-depth but accessible analyses. A scientific and societal impact PAGENS is part of an open science dynamic, with publication of articles in open access, creation of a life course database and dissemination of results in the form of podcasts, exhibitions and policy briefs. This project strengthens North-South collaborations and encourages dialogue between academic research and field expertise, thereby helping to ensure that issues relating to age and life course are taken into account in the development of public policies.

Keywords: sociology of life courses generation studies participatory research