Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The new standard for sustainable electrification of actuation contributing to a decarbonised Industry 5.0 (naXture)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2025-05-01
End date: 2027-04-30
Duration (months): 24.0
Total project cost (EUR): 3524710.0
EU funding (EUR): 2467297.0
Participants: 1
Project status: SIGNED

Current electric actuators are unable to support high force/ high speed, low power applications. These are important when it comes to tasks a human naturally does such as gripping or clamping. They represent 20% of industrial applications, and their relevance is quickly growing due to their importance in, for example, assembly or robotics. If these 20% cannot be electrified, industries don´t electrify the other 80%. They just keep relying on energy consuming (above 10% of energy consumption in Europe), very inefficient and polluting pneumatic or hydraulic actuators, due to the costs of maintaining two parallel infrastructures. The human muscle is the perfect actuator – it is sensitive, yet shock resistant; strong, yet compact. By uniquely imitating the working principles of the human muscle, we bring the missing piece for fully electrifying the industry. Our patented naXture platform uniquely combines solid-state actuators with integrated micro hydraulic circuits, to consume up to 75% less energy than existing solutions, achieving very high efficiency with ultra-dynamic and precise movement. Our small and light solution can be flexibly integrated in the smallest spaces. Our disruptive technology is protected by more than 100 patents, of which the majority is granted. Moreover, we have proven with leading industry players our ability to electrify processes that previously relied on pneumatics. However, our current cost is prohibitive for most industries, and our production process is manual, thus limiting us to niche markets.

Keywords: electrification,high performance electric actuators,industry 4 0,industry 5 0,robotics industrial internet of things,iiot,force density,solid state actuators,micro hydraulic circuits,industri
DIgitalisation for biocultural diVERsity and Environmental justice (DIVERSE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Human Mobility, Environment, and Space
Panel description: Human geography, demography, health, susta inability science, territorial planning, spatial analysis
Countries involved: Spain
Call: ERC CONSOLIDATOR GRANTS (ERC-2023-COG, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 2133101.0
EU funding (EUR): 2133101.0
Participants: 1
Project status: SIGNED

Does the digital divide deprive movements for environmental justice (EJ) and in defence of biocultural diversity from the benefits of digitalisation? DIVERSE’s hypotheses resist the idea. From drone monitoring of forests to indigenous digital media and online mapping to vindicate stories of resistance and transformation, a digital transformation from the ground up may not only be paving the way for just and diverse futures but also for an alternative understanding of digitalisation. Yet no large-scale scientific study has examined the occurrence of digitalisation in grassroots transformative initiatives (GTI) nor theorised its effects. While elite-and growth-driven digital innovations are redefining lifestyles and overall imaginaries of the future, a strong debate in the fields of political ecology and EJ involves two confronted views (celebratory vs technophobic) on the likelihood of enfranchising technologies. DIVERSE’s overarching goal is to theorise an alternative model of digital transformation rooted in relationality (care, community, personal connection) that emerges from GTI in their pursuit of diverse worlds and EJ. The ground-breaking approach combines qualitative data (from expert interviews and databases compilation worldwide, to case-studies and biographical interviews across continents) with quantitative methods and models to analyse these data (e.g., two newly created indices, transformative effectiveness and GTI digitalisation, and a first global compilation of digital practices in GTI), offering both an understanding of causal chains and a basis for generalisation. DIVERSE proposes the new concepts of “life-centred digitalisation” including both livelihoods and ecology, and “situated digital leadership”, disclosing the specific links of digitalisation with changes in material experiences, situated knowledge and place-based digital ecologies. My ultimate goal in terms of theory is to lay out the foundations of a political ecology of digitalisation.

Keywords: environmental justice biocultural diversity grassroots transformative initiatives digital transformations relationality life centred digitalisation situated digital leadership digital divide
Marine Protected Areas Europe (MPA Europe)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Biodiversity and Ecosystem Services
Action type: Research and Innovation actions
Countries involved: Norway,United Kingdom,Portugal,Denmark,France,Greece,China,Japan
Call: Improved science based maritime spatial planning and identification of marine protected areas (HORIZON-CL6-2021-BIODIV-01, 2021)
Start date: 2023-01-01
End date: 2026-04-30
Duration (months): 40.0
Total project cost (EUR): 2682228.25
EU funding (EUR): 2682228.0
Participants: 10
Project status: SIGNED

We will map the optimal locations for Marine Protected Areas (MPA) in European seas using measures covering the range of biodiversity from species to ecosystems, including habitats. The contribution of these measures to carbon storage will be quantified and mapped. The top 10% and 30% of the area that includes most species, habitats, and ecosystems, and maximises blue carbon benefits, will be prioritised as an MPA network. The geographic scope is the Atlantic Exclusive Economic Zones of the EU and its neighbours, and all of the Mediterranean, Baltic and Black Seas. Feedback from Marine Spatial Planning (MSP) stakeholders in the regional seas on the proposed MPA network and methodology will be reported. A first data-driven classification of ecosystems in European seas will use environmental data from Copernicus and EMODnet. Environmental niche models will map thousands of species and biogenic (fauna and flora structured) habitat ranges and add to existing seabed habitat maps in EMODnet. Analyses of spatial relationships between biodiversity measures and evidence of carbon storage will support the prioritisation analyses. Parallel modelling of current connectivity and the velocity of climate change will map connectivity within the proposed MPA network and how it will accommodate species distribution shifts due to anthropogenic climate change. All data and maps will be freely available through EMODnet, the Ocean Biodiversity Information System, EC Knowledge Centre for Biodiversity, and the project’s online atlas. The atlas will provide transparency, traceability and enable reproducibility of the results. Its synthesis will show stakeholders (MSP, NGO, students, researchers) why areas have been prioritised. The use of decision support software will enable alternative network designs based on stakeholder preferences and could thus support wider MSP beyond the subject and study area.

Keywords: marine spatial planning
Centre of Excellence of AI for Sustainable Living and Working (SustAInLivWork)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Lithuania,Finland,Germany
Call: Teaming for Excellence (HORIZON-WIDERA-2022-ACCESS-01-two-stage, 2022)
Start date: 2023-09-01
End date: 2029-08-31
Duration (months): 72.0
Total project cost (EUR): 14652000.0
EU funding (EUR): 14652000.0
Participants: 6
Project status: SIGNED

SustAInLivWork aims at creating a Centre of Excellence (CoE) in Lithuania for Sustainable Living and Working (SustAInLivWork), specialized in the development and application of R&I solutions based on Artificial Intelligence (AI) in the manufacturing, energy, health and transport sectors. This CoE will act as a lighthouse with far reaching impact strengthening R&I in the national and international scope, nurturing from a cooperation between key national partners - the four leading universities of the country- (KTU, VILNIUS TECH, VMU, LSMU) and advanced international ones (TAU, TUHH), that will contribute with their knowledge to boost value creation from advanced technologies. The CoE is necessary to improve the low development of AI based R&I solutions in the 4 mentioned sectors and to increase the sustainability of the country, by developing new business models and business process solutions with lower CO2 emissions, using Explainable AI to make those solutions safe, trustworthy and transparent. It will have an impact on the country and on the whole Baltic Sea Region and beyond, by the operation of 4 HUBs that will derive into new educational and training programmes, an enhanced cooperation with the private sector and public authorities and the creation of a Lithuanian AI Cluster to foster transition towards sustainability with a particular focus on the S3 priorities areas. It will finally improve the Lithuanian position in EU Innovation scoreboards, increase the international collaborations, mobilise national, European and other international funding programmes by creating service packages, AI labs and different collaborations both national and international.

Keywords: artificial intelligence sustainable living sustainable working centre of excellence
A decision within a decision: Exploring the psychological, electrophysiological and computational mechanisms underlying changes of mind and metacognitive judgements. (MetaChange)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Czechia,Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-06-15
End date: 2025-06-14
Duration (months): 24.0
Total project cost (EUR): 166278.72
EU funding (EUR): 166278.72
Participants: 2
Project status: CLOSED

MetaChange is an original and innovative project combining large scale online psychophysics experiments, invasive electrophysiological recordings in epileptic patients and computational modeling in order to brush a comprehensive picture of the effect of post-decisional information on the cognitive and metacognitive components of decision making. The project will use a causal approach based on stimulus manipulation or direct brain stimulation to explore the effects of post-decisional information on these components of decision making, and assess how these effects unfold in time. We also aim at determining the neuronal mechanisms supporting decisional and post-decisional integration, as well as their link with metacognitive processes such as confidence ratings and changes of mind. Finally, we intend to develop a computational model of decision making rooted in evidence accumulation, accounting not only for response times and response accuracy but also for changes of mind and confidence ratings. Overall, MetaChange aims to address in an interdisciplinary and synthetic manner some of the current challenges in the field of decision making and metacognition.

Keywords: decision making,metacognition,evidence accumulation,epilepsy,invasive recordings,electrical stimulations
Self-feeding implants to improve and accelerate tissue healing using nutritional nanoparticles (NutriBone)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2024-12-01
End date: 2026-05-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Keeping large (>1cm3) living tissues alive is an unresolved key challenge that hinders many clinical and industrial applications, including tissue/organ transplants, engineered tissues, drug screening models, and lab grown meat. While natural tissues within our body are continuously provided with nutrients via the blood stream, engineered, explanted, or even implanted tissues have to rely on the slow diffusion of nutrients until perfused vascularization is achieved. This commonly leads to tissue starvation, which inevitably causes tissue failure. The NutriBone project is based on the logical yet never before explored premise that these tissues need to provide their own nutrients if the environment cannot do so. This is an innovative concept named self-feeding. We have surprisingly discovered that glycogen offers cell-driven long-term release of physiologically relevant quantities of glucose enabling long-term implant survival, accelerated tissue formation, reduced inflammation and immune responses, and improved vascularization. As this approach is a first-of-its-kind, we have patented it and here propose its valorisation. We propose to develop a marketable self-feeding bone implant to address the current clinical challenge of critically sized bone defects. Although our technology is relevant for many clinical applications, we will focus on large bone defects. Bone is the second most implanted tissue but implant failure remains high, leading to high medical cost and low quality of life for patients. Moreover, bone implants represent the largest, and still fast growing market for engineered tissues, while awaiting a solution to maintain implant viability. Thus, we can foresee a concrete path-to-market. To this end, we will perform product development towards a minimum viable product, establishing a roadmap for certification, and market research as well business plan development to ensure a good product-market fit including a market entry and exit strategy.
Localize and Controlled co-delivery of AuNPs conjugated siRNA by Cationic Shear-thinning Gel Matrix for Treatment of Arthritis (DesiRTA) (DesiRTA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Ireland,Portugal
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-04-01
End date: 2026-03-31
Duration (months): 24.0
Total project cost (EUR): 199694.4
EU funding (EUR): 199694.4
Participants: 2
Project status: SIGNED

Arthritis is a common metabolic and immune associate disease that causes chronic pain and inflammation in a joint. Approximately 312 million people are affected by arthritis globally. It affects adults of all ages, both sexes, and all races and ethnicities, but the prevalence in women is more than in men. Professional organizations have established many arthritis treatment regimens and management guidelines; in those nonsteroidal anti-inflammatory drugs (NSAIDs), steroids and biologicals are the main ones. These are effective against the disease aggressiveness and pain up to some extent, but the problem is this treatment is only symptomatic and requires taking them lifelong; in that case, these drugs cause severe health problems and again increase the economic burden. For these reasons, we need to develop a therapeutic technique and medication that can eliminate the symptom and causes of the disease forever and prevent the ever-increasing number of patients worldwide. DesiTRA projects are an effort in the same vein to develop an effective therapeutic alternative for arthritis that will avoid the aggravation of disease symptoms and cause of the disease together, without causing any health-associated side effects. In this, mainly gold nanoparticle (AuNPs) conjugated siRNA will be delivered at the disease site locally. Modified polysaccharides will increase the stability and release rate of AuNPs-siRNA, and these assemblies will be delivered very controlled and precisely through a synovial fluid mimicking the shear-thinning hydrogel system. The ambitious project will be conducted at two different groups and laboratories in Ireland and Portugal. The project involves experienced researchers of other but related areas that will allow applicants to work in multidisciplinary aspects. The prestigious fellowship will provide a plate form of renowned subject experts, and exposure to international collaborators will provide a unique opportunity to grow as a true researcher

Keywords: biomedical engineering
Acoustofluidic thin-film actuated chip for exosome separation from blood (AcouSome)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Sweden,Denmark,Italy
Call: EIC Transition Open 2022 (HORIZON-EIC-2022-TRANSITION-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 2498421.25
EU funding (EUR): 2498419.0
Participants: 4
Project status: SIGNED

AcouSome is a consortium stemming from the ongoing EIC-FET Open BioWings project, and consists of four of the BioWings project partners (AcouSort AB, DTU, Lund University and Day One Srl). AcouSome has the ambition to build on the disruptive technology of thin film actuated acoustofluidics developed in BioWings. The results obtained in BioWings will be combined with a polymer acoustofluidics technology developed in the ongoing Eurostars AcouPlast project to fabricate a polymer-based microfluidic chip for separating and enriching exosomes from blood for use in the next generation of point-of-care diagnostics. Exosomes are nano-sized extracellular vesicles that are released by a significant number of different cell types. They are considered an important biomarker, with high diagnostic potential in a wide range of diseases, including different kinds of cancer (glioblastoma, melanoma, prostate cancer and many others), hepatitis, kidney, cardiovascular and liver diseases. Therefore, there is an increasing interest in exosomes as a powerful diagnostic tool. Having the opportunity to isolate and analyze exosomes from a routine blood test is crucial for early detection of a wide range of diseases. In the AcouSome chip exosomes will be separated and enriched from blood by combining two steps already developed by Lund University and AcouSort. First plasma will be separated from blood by flowing the blood through a microfluidic channel, pushing the cells towards the centerline of the channel using ultrasoundand and subsequently splitting the cell and plasma flows. Exosomes will then be trapped and enriched from the plasma flow using a localized acoustic field. The acoustofluidic chip will be driven using thin-film actuators as invented together with DTU in the BioWings project. The exosome separation cartridge is intended for sample preparation in research labs and future diagnostic point-of-care instruments.

Keywords: microfluidics,lab on a chip,acoustofluidics,point of care diagnostics,blood diagnostics,exosomes,extracellular vesicles,transducer materials
Computational Discovery of Numerical Algorithms for Animation and Simulation of Natural Phenomena (CoDiNA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer Science and Informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Austria
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-06-01
End date: 2027-05-31
Duration (months): 60.0
Total project cost (EUR): 1936503.0
EU funding (EUR): 1936503.0
Participants: 1
Project status: SIGNED

Modern numerical algorithms and high performance computing systems are capable of simulating physical systems far more efficiently than those from just few years ago. However, this recent increase in computational power comes with an insatiable demand for complexity and scale: scientists and artists now wish to model textiles at the level of individual fibers and simulate oceans down to the smallest ripple. The typical strategy of analytically deriving integrators and hand-tuning parameters will inevitably fail to cope with the increasing non-linearity and complexity of these problems. This shift in problem complexity necessitates entirely novel strategies for discovering numerical algorithms. We will redefine the state of the art in numerical simulation and animation by combining three different approaches: First, we will develop analytical tools customized for large scales; we will derive optimal numerical algorithms by viewing physics through the lens of computational complexity, and by observing limiting behaviors as problems increase in size. Next, we will gain physical insights by simulating huge numbers of smaller simulations and generating large data sets. By discovering trends in this data, we will faithfully approximate aggregate behaviors in systems that are far too complex for analytical techniques to penetrate. Finally, by framing the derivation of numerical algorithms as a constrained optimization problem, we will be able to deliver provably optimal code for a given piece of hardware and precisely control accuracy/efficiency trade-offs. The combination of these research directions will enable efficient simulations of massively complicated systems that are currently unfeasible to compute. Due to the timely and groundbreaking nature of these proposed directions, we also expect to develop entirely unprecedented methods for physics simulation and discover a number of theoretical insights and scientific advances along the way.

Keywords: physics based animation,fluid animation,fracture animation,numerical algorithms,numerical homogenization