Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Deploying High Capacity Dense Small Cell Heterogeneous Networks (DECADE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Sweden,United Kingdom,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2015-08-01
End date: 2019-07-31
Duration (months): 48.0
Total project cost (EUR): 634500.0
EU funding (EUR): 634500.0
Participants: 4
Project status: CLOSED

Broadband mobile networks are experiencing exponential traffic growth. It is predicted that this trend will continue in the next five to ten years with an estimated compound annual growth rate of 0.6 to 1.0. Hence the traffic (mostly data) carried by a mobile operator’s network in 2022 could be over 1000 times of that in 2012. This traffic growth presents a huge challenge to both the mobile industry and to academic researchers. Along with increased spectrum efficiency, spectrum bandwidth expansion and traffic offloading through WiFi, small cell deployment is regarded as one of the most promising ways to meet the use of broadband mobile service in both outdoor and in particular indoor scenarios in the next decade. The deployment of small cells in a macrocell coverage area leads to a multi-tier heterogeneous network (HetNet), in which a mix of access node types, such as macrocell, femtocell and relay, will co-exist. Despite the current research and development on small cell/HetNet from both industry and academia, there are still many challenges to be addressed and questions to be answered for successful small cell and HetNet deployment. These challenges range from the lack of fundamental understanding of HetNet network capacity to the need of Radio Access Network (RAN) Planning and Optimisation (PO) tool for HetNet deployment involving both indoor and outdoor scenarios. The DECADE project adopts the scheme of Research and Innovation Staff Exchange (RISE), with the effect of inter-sectorial efforts and knowledge integration to tackle the challenges in HetNet planning and optimization. The research consists in fundamental capacity analysis, system modeling, algorithm development, and performance engineering for HetNets. In addition, DECADE serves as a solid platform to promote long-term collaboration between academia and industry collaboration in a rapidly evolving area of Information and Communication Technologies (ICT) in Europe.

Keywords: heterogeneous networks,mobile broadband,planning and optimisation,small cell
eco-friendly Ship Hull film system with fouling Release and fuel saving properties (eSHaRk)

Framework: Horizon 2020 — Societal Challenges
Action type: Innovation actions
Countries involved: Germany,Germany,Belgium,Netherlands,Netherlands
Call: Fast Track to Innovation Pilot (H2020-FTIPilot-2015-1, 2015)
Start date: 2015-12-01
End date: 2019-05-31
Duration (months): 42.0
Total project cost (EUR): 2823718.75
EU funding (EUR): 2055165.63
Participants: 6
Project status: CLOSED

The aim of the eSHaRk project is to finalise the development of an innovative new fouling protection system for commercial vessels, and to accelerate its market entry. Fouling, defined as the settlement and growth of marine plants and animals on submerged structures, is a constant challenge for the shipping industry. Fouling results in higher hydrodynamic drag of vessels, which in turn translates into higher fuel usage and greenhouse gas emissions. A number of fouling protection technologies exist on the market, the most widely used being paint-based anti-fouling and fouling release coatings. However, these existing solutions face a number of challenges concerning their environmental impact, the efficiency of their application on ship hulls, and their effectiveness in protecting vessels against fouling. The eSHaRk project aims to bring a new and innovative solution to the market, which will lead to a paradigm shift in the fouling protection business. This solution is based on self-adhesive foil technology, which not only maintains the current state-of-the-art fouling protection standards but is superior to existing paint-based solutions in terms of eco-friendliness, easiness of application, robustness, and drag reduction effects leading to fuel savings and reduction of GHG emissions. As part of the eSHaRk project, the surface morphology of the foil will be optimised to enhance its drag reduction, fuel savings and emissions reduction benefits. In addition, a robotised laminator will be finalised to apply the foil on large commercial vessels in an automated way. A cruise vessel will be equipped with the foil to ensure full-scale testing and validation in operational conditions before market entry. The technology will then be ready for commercialisation immediately after project end, in late 2018.

Keywords: fouling release,drag reduction,non toxic,fuel savings,low ghg emissions
Scaling of a midsized patented low energy, light weight, highly efficient actuator to meet the demands of smaller and larger scale functions (SmartAct-2-3)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: United Kingdom
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2014, 2014)
Start date: 2014-10-01
End date: 2015-02-28
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The Smart Actuator Company Ltd develops smart, RIFT Driven® actuators our first was delivered to market in Q3-2013. The system is proven to use 25% less copper, be 80% lighter and 75% more energy efficient than our competitors. Early success means that the first two years production scheduling is already sold to 90% capacity and The Smart Actuator Company now own global rights for the use of RIFT Technology in electrically powered actuators. Put simply, we believe our technology is a game changing product capable of delivering benefits worldwide by dramatically reducing; • energy required to automate everyday tasks in many applications • volume of raw materials, including copper and magnets, used to manufacture automated systems • inventory and therefore administration complexity • weight, thereby reducing fuel use in logistics and shipping • Carbon Footprint in manufacturing and distribution • need for sourcing manufacturing capability outside Europe

Keywords: low energy,low resource,high efficiency,smart actuator
Cell-type Specific Mechanisms and Functional Consequences of Altered NMDA Receptor Development and Mecp2 Deficiency on Developing Cortical Circuits (NMDARETT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-04-01
End date: 2018-08-02
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

NMDA receptor (NMDAR) dysfunction has been identified in multiple genetic causes of autism and related neurodevelopmental disorders. I recently showed that loss of Mecp2, the cause of Rett syndrome and some cases of autism, differentially affects NMDAR development at cortical synapses on specific cell-types: slowing down the development in excitatory pyramidal neurons and accelerating the maturation in parvalbumin-positive (PV) inhibitory interneurons. Genetic manipulation of NMDAR expression in Mecp2-deficient mice rescued both cortical function and the premature NMDAR maturation in PV cells. Based on these findings, I hypothesize that this cell-type specific disruption of NMDAR development leads to an imbalance in excitation and inhibition in the developing cortical circuits. To test this idea, I will combine single cell genomic and cell-type specific recording techniques to elucidate how Mecp2 controls the development of synaptic receptors and the impact on network function. In Aim 1, I will use cutting-edge techniques for single-cell RNA sequencing and synaptic recordings of NMDAR maturation in cortical cultures to identify novel cell-type specific mechanisms underlying NMDAR development and the regulation by Mecp2. In Aim 2, I will investigate the functional effects of Mecp2 deficiency and altered NMDAR maturation on the development of cortical network activity using two-photon calcium imaging and multi-electrode array (MEA) recordings. As a neuroscientist and neurologist, this training will prepare me for an independent research career addressing the circuit-based defects underlying Rett syndrome and autism. I have the full support of the University of Cambridge and Wellcome Trust Sanger Institute for the proposed research and my career development. This study will improve our understanding of how loss of Mecp2 alters cortical circuits and has the potential to identify novel cell-type specific targets for developing new therapies for Rett syndrome.

Keywords: nmda receptors,rett syndrome,development of excitatory synaptic transmission
Enhancing the EOSC portal and connecting thematic clouds (EOSC Enhance)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: EOSC ecosystem
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Italy,Finland,Greece,Poland,Greece,Norway,Poland,Belgium,France,France,Netherlands,United Kingdom,United Kingdom
Call: Enhancing the EOSC portal and connecting thematic clouds (H2020-INFRAEOSC-2019-2, 2019)
Start date: 2019-12-01
End date: 2021-11-30
Duration (months): 24.0
Total project cost (EUR): 1999700.0
EU funding (EUR): 1999700.0
Participants: 21
Project status: CLOSED

EOSC Enhance pursues 4 objectives: 1: Enhance the service provider interface and incorporate new services and resources into the EOSC catalogue 2: Accelerate the deployment and uptake of EOSC services and resources 3: Increase user demand for EOSC services and resources via portal improvements and development 4: Enabling easier access to thematic clouds services and data EOSC Enhance will improve and enhance the discoverability of scientific services and data resources by further developing and widening the EOSC catalogue. This will be done through the integration of additional services and data resources (notably the ESFRI clusters and thematic and geographic clouds) as well as further technical enhancement of the functionalities for service providers (Open APIs, AAI) and users (search and comparison tools, etc.). Quality reports will be provided to service providers. We will facilitate interoperability and discoverability of services and resources across scientific disciplines by linking up thematic and regional/national service providers (public and commercial), gateways, aggregators and marketplaces. The EOSC Portal will apply the emerging EOSC Rules of Participation (RoP) and will focus on processes, specifications, guidelines, tools and APIs to support service and resource providers in making them interoperable. We will consolidate the EOSC Portal as the point of access for researchers through the facilitation and continuous enhancement of findability and discoverability -by appropriately design of the UI for example- inherent building blocks addressed in the EOSC Enhance project - that will make this possible. The critical technical aspects and features of the EOSC Portal will be discussed and agreed with ESFRI clusters to enhance interoperability and avoid frictions for users. The outcomes will be channelled to the EOSC Architecture WG in charge of submitting ideas for overall adoption of technical solutions by the EOSC Governance bodies.

Keywords: open science,data,research infrastructures,researchers,service providers
Real-time reaction, autonomous and energy-efficient snowmelt technology for lightly and heavily trafficked pavement surfaces. (Snowless)

Framework: Horizon 2020 — Industrial Leadership
Action type: Innovation actions
Countries involved: Germany,Israel,Netherlands,Denmark
Call: Fast Track to Innovation (FTI) (H2020-EIC-FTI-2018-2020, 2018)
Start date: 2018-11-01
End date: 2022-08-31
Duration (months): 46.0
Total project cost (EUR): 3296963.75
EU funding (EUR): 2423537.38
Participants: 5
Project status: CLOSED

Winter conditions on roads cause traffic delays that cost 1% of EU GDP and 1,000 causalities annually. Similarly, snow fall causes air traffic disturbance that can cost €57.3M per storm. For pedestrians it a major health issue as an increase of 25% increase in hospitalization and 33% rise in cases of hip fractures is observed during winter season. Current solutions suffer from many shortcomings. The most popular, plowing and salting, is manual, has low response times, damages traffic surfaces, vehicle corrosion and environment pollution. To answer this need we have developed SNOWLESS, a snow melting solution comprising of our proprietary amorphous alloy heating ribbons that are embedded in pavements and completely automatic control unit with real-time dynamic response. Our prioritization scheme for segmented heating zones ensures real-time response (15 minutes from automatic snow/ice detection), low annual operational costs of €1.2/m2, almost no maintenance, 30-60% reduction power consumption. Our solution is environmentally friendly, prevents asphalt cracking by reducing the temperature amplitude and promotes self-healing in the asphalt itself. Our commercialization targets Scandinavia, Central Europe and North America, a market worth €1.75B for shopping malls, roads, pedestrian walkways and airports driven by demand for sustainable snow removal alternative. SNOWLESS has already been implemented in parking lots, successfully reducing operational costs, with the installations generating €1.5M in sales over the last 3 years. We intend commercialize SNOWLESS 3 years after development, ideally by 2021 in 2 phases, with initial introduction to shopping mall parkings which have less stringent requirements and then progress to difficult applications such airports and road infrastructure. We anticipate a revenue and profit of €50M and €15M respectively coming from sales over 5 years, creating 21 employment opportunities in the process.

Keywords: snow remowal,ice removal,deicing,winter conditions,winter traffic,pavement heating,road infrastructure
Identification and characterization of new drug resistance and host adaptation mechanisms in Mycobacterium leprae (LEPVORS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland,United States
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2022-01-31
Duration (months): 33.0
Total project cost (EUR): 153916.2
EU funding (EUR): 153916.2
Participants: 2
Project status: CLOSED

Leprosy is a multiform infection caused by Mycobacterium leprae, an uncultivable bacLeprosy is a slow and chronic infection caused by Mycobacterium leprae. Recent advances in the next generation sequencing offer a new possibility to study the physiopathology of M. leprae, an uncultivable bacteria on anexic media. In 2018, the comparative analysis of 154 M. leprae genomes from 25 countries identified three hypermutated genes including two (ribD and fadD9) probably associated with drug-resistant and the most mutated one being ml0411 with a potential role in host adaptation. In a mycobacterial species, like M. leprae, with such a reduced number of coding genes, it is reasonable to assume that this high rate of mutations probably led to the modification of essential biological functions. In addition, the recent development of more efficient molecular tools can now help to obtain the whole genome sequencing of the strain from the low representative forms of the disease. This could help to identify more of these highly mutated genes and establish a link between the pathogen genetic and the clinical disease outcome. This project proposes to functionally characterize some of the mutations identified but also to identify new candidates which could be linked with differences in host phenotype. The study has three specific aims: Specific aim 1 will focus on potential new genes involved in M. leprae drug resistance. Using surrogate mycobacteria such as M. tuberculosis and M. haemophilum, we will test the drug susceptibility of mutated strains in fadD9 and ribD compared to wild-type strains. In specific aim 2, we will investigate the role of ml0411 and mutated version on the host innate immune response modulation In specific aim 3, we will focus on the whole genome sequencing of M. leprae strain from the less represented clinical form of leprosy, the tuberculoid pole to identify new genetic differences in the bacteria which could be associated with different host phenotypes.

Keywords: leprosy,mycobacterium leprae,drug resistance,virulence,host pathogen interraction,genomics,innate immune response
Hybrid Electrocatalysts Inspired by the Nitrogenase Enzyme (HEINE)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Switzerland
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2019-10-01
End date: 2024-09-30
Duration (months): 60.0
Total project cost (EUR): 1498445.0
EU funding (EUR): 1498445.0
Participants: 1
Project status: SIGNED

Artificial nitrogen reduction to ammonia using the Haber-Bosch process directly supports half of the global food production and accounts for 2% of the global energy consumption. This large consumption of energy originates mostly from the use of H2 (derived from fossil fuels) as a reductant and from the high pressure and temperature required to undertake the Haber-Bosch process. Electrochemical synthesis of ammonia, using a proton and electron source combined with an electrocatalyst at room temperature to reduce N2, thus presents an appealing, energy-efficient alternative. However, despite years of research, the few currently available catalysts have very limited efficiency in N2 electroreduction. Drawing inspiration from biochemistry and using the tools of coordination chemistry, catalysis and surface chemistry, this project will explore an original strategy to develop catalysts for the reduction of N2 inspired by the nitrogenase enzyme. Motivated by the recent discovery of two unique moieties in the nitrogenase cofactor – the presence of a µ6-carbide moiety and a Mo(III) center – and of the increased understanding of substrate pathways in the nitrogenase protein structure, the goal of HEINE is to design new hybrid catalysts based on the immobilisation of accurate mimics of the nitrogenase active sites onto heterogeneous supports used to generate properties analogous of the protein scaffold (hydrophobicity, proton relays, etc.). This will provide us with novel ways to develop functional electrocatalysts for N2 reduction in ambient conditions, combining the activity of traditional solid-state systems, with the selectivity of molecular catalysts. By identifying and reproducing the parameters responsible for the unique activity of nitrogenase enzymes, HEINE will yield invaluable information on nature’s routes to N2 reduction and will pave the way towards a new generation of electrocatalysts able to promote this reaction.

Keywords: n2 reduction,cluster synthesis,low valent molybdenum,electrocatalysis,surface chemistry
Accurate irrigation controller with multi-sensoring and interactive cloud-based platform to evaluate real plant needs and save up to 80% of water (RAINOLVE)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Spain,Italy
Call: Boosting the potential of small businesses in the areas of climate action, environment, resource efficiency and raw materials (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2017-03-01
End date: 2017-06-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

Water scarcity and droughts costed Europe over 100 billion € in the past 30 years. With the water prices expected to increase in Europe by between +20% up to even 400%, savings in water have become a priority issue for irrigation professionals. Inappropriate irrigation techniques has a great impact on yield (average loss of 20-40%), plant disease (increase of 15-35%) and input costs (average over spending of 25%).For instance, municipalities in Europe, like London with 14.000ha green areas, are spending an average of 15,000€/year/ha for water irrigation costs. Under this context, Precision Irrigation such us irrigation controllers is the only option. This growing technology which optimizes the usage of water is expected to expand its market share by 13% from 2016 to 2023. RAINOLVE is the fruit of a collaboration between RAIN, an Italian engineering and manufacture leader in irrigation products; and INOLVE, a Spanish SME specialized in software, for the development of an accurate irrigation controller. RAINOLVE is a multi-sensor coupled with intelligent cloud-based platform with vast botanical and agronomical database to calculate and check the exact plant needs in function of each site conditions. RAINOLVE will provide a highly accurate irrigation technology with low return over investment (less than 1 year) allowing savings up to 18,000€/ha/year: water (80%), fertilizer (40%), time (1day/week) and plant disease (60%). RAINOLVE technology stands in a TRL7, with a real scale prototype tested in different field sites. RAINOLVE project main objective is to optimize, test and validate the technology to take it to industrial production and successful commercialization. We estimate that RAINOLVE will be able to save annually 9,200M m3 of water in Europe, accounting for €1.5 billion per year.

Keywords: irrigation,plant needs,water saving,irrigation technology,platform,efficiency,irrigation controller,precision irrigation