Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Recovering Past Stories for the Future: A Synergistic Approach to Textual and Oral Heritage of Small Communities (RESTORY)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Romania,Iceland,Portugal,Finland,Estonia,Poland,Italy,Belgium,Greece,France,Ireland,Ukraine
Call: Cultural heritage in transformation – facing change with confidence (HORIZON-CL2-2023-HERITAGE-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 3000000.0
EU funding (EUR): 3000000.0
Participants: 20
Project status: SIGNED

The project builds synergistically upon textual and oral stories to explore the past of small communities, with the goal of restoring the public’s emotional connection to discontinued traditions. In doing so, it pays greater attention to segments of cultural heritage that have long been overshadowed by monuments or sites of larger significance. Texts and interviews encapsulate expressions of collective agency, allowing current-day SSH academics to investigate those natural processes that gave prominence to the effective management of limited supplies of human and material resources. With a focus on schooling, recycling practices, and affective-based communication of group agents, RESTORY intends to investigate the formation of sustainable attitudes and strategies, learn from the lessons of the past, and integrate them into the future configuration of commitments. Ultimately, emulating the resource maximization frameworks intuitively designed by small-scale communities over a long period of time will allow the transfer of know-how from academia to local memory institutions, stakeholders, and citizens, contributing to the sustainable development of the continuously transformative heritage contexts. The research aspects of the project will consist of methodologically-hybrid case studies, targeting the textual and oral heritage of the communities inhabited in the past by Transylvanian Saxons, a group of German-speaking colonists settled about 800 years ago in nowadays Romania, in conjunction with 10 international case studies, all offering a wider range of expertise and accumulation of knowledge within the research target. RESTORY also presents the opportunity to attract cultural professionals from archives, museums, and libraries to training sessions designed to enhance the correct and comprehensive management, conservation, and capitalization of cultural heritage, all in relation to the needs of the wider public and administrative decision-makers at a local level.

Keywords: cultural heritage small communities resource management recycling learning storytelling oral history archive,library,museum
Identity Attributes Matrix Initiative (IAMI)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Fighting Crime and Terrorism
Action type: Research and Innovation actions
Countries involved: Germany,Italy,Czechia,Poland,Spain,Finland,Greece,Austria,Romania,France,Israel,United Kingdom,Moldova, Republic of,Cyprus,Iceland
Call: Open Topic (HORIZON-CL3-2023-FCT-01, 2023)
Start date: 2025-02-01
End date: 2028-01-31
Duration (months): 36.0
Total project cost (EUR): 3746252.47
EU funding (EUR): 3746252.47
Participants: 20
Project status: SIGNED

IAMI aims to revolutionize entity identification and resolution in security, intelligence, and investigation contexts. It addresses the challenges and limitations faced by current identification techniques and offers a visionary solution through advanced AI-powered software. The project's long-term vision is to propel EU LEAs and security/intelligence organizations into a new era of intelligence, investigation, and forensic capabilities. IAMI's core innovation is the development of an AI-powered software system that can seamlessly integrate with existing case management systems and analytic tools. At the heart of IAMI is the concept of the 'Identity-Attributes-Matrix (IAM)', a 3D construct that encompasses a broad spectrum of multi-modal identity-related attributes, including biometric data, non-biometric identity-related data, and analytic results. These attributes are used to facilitate large-scale entity identification/resolution, including a broader range of entity types, simultaneous and rapid multi-entity identification/resolution, systematic and continuous analysis of flux of probe attributes, confidence in noisy/corrupted probe data, reduced false positive rates, access to contact attributes, and the ability to classify fake identities and bots/avatars. Furthermore, IAMI sets the groundwork for effective collaboration and data sharing across European agencies, including international organizations like EUROPOL and INTERPOL through the establishment of a new EU-Wide IAMI enrolled data collection repository for terrorist threat assessment and awareness which enriches their capabilities and assets. The realization of IAMI's vision will be achieved through the demonstration of the developed IAMI solution. It will be communicated and disseminated among EU LEAs and security/intelligence agencies through project activities, including deliverables, training curricula, workshops, and pilots. IAMI represents a significant step forward in EU fight against terrorism.

Keywords: entity identification and entity resolution
LIfestyle-Genotype Holistic inTeractions on mortality (LIGHT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 194074.56
EU funding (EUR): 194074.56
Participants: 1
Project status: SIGNED

The LIGHT project (“LIfestyle-Genotype Holistic inTeractions on mortality”) investigates the interactions between polygenic risk scores (PRSs) and key lifestyle factors—physical activity, smoking, alcohol use, and diet quality—on all-cause mortality in a Southern European population, aiming to improve personalized health recommendations. The project will leverage data from the CORDELIA meta-cohort, encompassing 196,632 participants with up to 30 years of follow-up, to calculate PRSs based on the latest genome-wide association studies (GWAS) and harmonize lifestyle variables across cohorts. The main objectives are: 1) Calculate all PRSs available for diseases and risk factors using the most updated GWAS studies and CORDELIA genotype data; and 2) Identify and validate interactions between PRSs and lifestyle factors on mortality risk in both a Discovery phase and a Replication phase. The project employs an interdisciplinary approach, integrating genetic epidemiology, public health, personalized medicine, and advanced statistical methods, with a focus on the gender dimension. The LIGHT project will allow a Career Development Plan that focuses on advancing my skills in project management, leadership, and funding acquisition through formal training, mentorship, and hands-on experience, positioning me for a tenure-track position and leadership within the CORDELIA network. By the project's end, LIGHT will establish new protocols for gene-lifestyle interaction studies, contribute to public health strategies, and generate open-access educational materials, while also addressing European health priorities and contributing to the UN Sustainable Development Goals. The results are expected to enhance personalized health interventions, reduce healthcare costs, and improve population health and life expectancy.

Keywords: lifestyle genotype interactions all cause mortality physical activity smoking alcohol diet quality
SINGle-cell mapping of Living kidney donation for the Assessment of Renal adaptation (SINGuLAR)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-04-01
End date: 2031-03-31
Duration (months): 60.0
Total project cost (EUR): 1499989.0
EU funding (EUR): 1499989.0
Participants: 1
Project status: SIGNED

>850 million people are affected by kidney disease, which is caused by kidney injury. Following injury, kidney cells have a remarkable ability to adapt. Previous studies have largely focused on kidney injury signatures, yet treatments successfully targeting injury in animals have failed in humans. Studies focused not on injury but on adaptation are lacking. The main reason for this is that studying kidney adaptation with existing methods is challenging due to the low signal-to-noise ratio of adaptation in the presence of injury. Instead of studying adaptation in kidney injury patients, SINGuLAR will therefore study isolated adaptation in living kidney donors: Donors, who irreversibly lose 50% of their kidney mass and function, show astonishing compensatory growth and functional adaptation. Studying the remaining kidney after contralateral organ loss allows to leverage an unbiased system free from injury-related noise. Since tissue biopsies from remaining kidneys that adapt well put living donors at disproportionately high risk, SINGuLAR will use renal cells shed into urine to create the first prospective single-cell transcriptomic map of kidney adaptation (Aim1). Additionally, we will investigate whether remaining kidney adaptation is epigenetically wired (Aim2) and how this process is spatiotemporally patterned (Aim3). SINGuLAR will also assess whether multi-omic data from remaining kidneys in donors correlate with outcomes of donated partner organs in recipients (Aim4), and it will leverage urine-derived tubuloids to enable patient-specific drug targeting (Aim5). By employing the remaining kidney as a one-of-a-kind human model, SINGuLAR aims to obtain unprecedented spatiotemporal insights into the biology of kidney adaptation and compensatory growth, which can subsequently be harnessed to therapeutically enhance organ adaptation in future kidney injury contexts.
Synapse dynamics across sleep-wake states (SLEEPYSYNAPSE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2025-11-01
End date: 2030-10-31
Duration (months): 60.0
Total project cost (EUR): 3492265.0
EU funding (EUR): 3492265.0
Participants: 1
Project status: SIGNED

Sleep is essential, yet its core functions and regulatory mechanisms are not fully understood. The synaptic homeostasis hypothesis suggests sleep helps normalize synapse strength and number accumulated during wakefulness. We have developed a zebrafish model for directly visualizing dynamic synaptic changes in single neurons across sleep/wake states. Our research indicates that synaptic changes in single neurons vary significantly across similar neuronal types under baseline conditions. Notably, only sleep periods with high sleep pressure—such as at the start of the night, after sleep deprivation, or with artificially elevated adenosine levels—support net synaptic removal. Aim 1 investigates how sleep/wake-dependent changes in synaptic number and strength relate to neuronal activity. We will use single-neuron synapse labeling combined with genetically encoded calcium imaging to observe how activity affects synaptic dynamics during sleep and wakefulness. Chemogenetic tools will help us test if wake activity shapes subsequent synaptic changes during sleep and if single-synapse activity tags synapses for preservation or removal. Aim 2 explores how sleep pressure signals affect single neurons. By mapping adenosine and noradrenaline release with new sensors across the sleep/wake cycle, we will analyze their impact on sleep-dependent synaptic changes, including in zebrafish sleep homeostasis mutants. Aim 3 examines how synaptic dynamics influence behavioral states. Using transgenic zebrafish to track synapses in key sleep/wake-regulating neurons (e.g., galaninergic, serotonergic, orexin/hypocretin, and noradrenaline-producing neurons), we will investigate if changes in synaptic dynamics are related to sleep pressure and how they affect behavioral state transitions. This project advances our understanding of sleep by employing novel imaging and genetic tools in zebrafish to provide insights into the interplay between sleep pressure, neuronal activity, and synaptic dynamics.

Keywords: sleep,sleep homeostasis,synapses,neuronal activity,zebrafish
The NeoKidney: next generation hemodialysis device making hemodialysis finally portable (PORTADIALYS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 30.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Hemodialysis (HD) is life-saving to patients with kidney failure. In 2023, ~4.1 million people globally were on dialysis, predominantly in-center HD (ICHD) which covers ~88% of patients. ICHD has significant drawbacks: suboptimal health outcomes (life expectancy of ~6 years), reduced quality of life, high healthcare costs (€92k per patient per year), and increased strain on healthcare personnel. Thus there is a push by patients, governments, insurers, hospitals to transition to home hemodialysis (HHD). HHD has better patient outcomes (up to 12 years life expectancy), higher quality of life and reduced costs (up to ~43% decrease in healthcare costs). Unfortunately, despite the advantages and the push currently only 1% of patients due to challenges of setting up existing HHD devices in patients homes. Current home hemodialysis (HHD) devices are bulky (~35kg), require extensive home retooling (additional costs of €5-10k), require large dialysate volumes (>25L) and are not truly portable, limiting patient freedom. To solve the current issues with HHD devices, we developed the revolutionary first-in-class NeoKidney which will be the only device on the market that is truly portable and plug-and-play (can be used without any home retooling) and thus is easy to setup and can be used anywhere by patients (at home, vacation). NeoKidney is the smallest device (only 10kg weight) and uses the least amount of dialysate (only 5L) on the market. Our unique proprietary technologies (IP portfolio >175 worldwide) underpin this innovation and create a special dialysis process that no company can replicate. The unique features of NeoKidney will help overcome the current issues that keep HHD penetration low, and will help significantly increase adoption form ICHD to HHD. This will significantly improve patient lives while providing for a strong business case. NeoKidney has the potential to reach €711M at peak sales per year in the €35 Billion hemodialysis market.

Keywords: hemodialysis,home hemodialysis,portable dialysis,kidney failure,end stage renal failure,novel technology
Empowering European industry with HKM1800: Scalable robotic automation for a high-speed world (HKM1800)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Cognibotics, a deep-tech Swedish company, pioneers innovation in high-performance automation for logistics and manufacturing. Building on two decades of research in hybrid kinematics and motion control, the company introduces the HKM1800 - a new class of high-speed, long-reach industrial robot designed to overcome the inherent trade-offs of today’s robotic systems. The HKM1800 addresses critical limitations in current industrial automation: slow throughput, limited reach, and high integration complexity. Conventional 6-axis robots are flexible but heavy and slow, while delta robots are fast but constrained to small workspaces. The HKM1800 combines the strengths of both through a proprietary hybrid-kinematic architecture and Juliet & Romeo™, Cognibotics’ open, real-time motion control software. The result is a lightweight robot - only 25 kg versus 200 kg for comparable systems - capable of over 2,000 picks per hour across a 10 m² workspace, delivering up to ⅓ more energy savings and reduction in material use and CO2 emissions. Currently at TRL6, the HKM1800 has demonstrated initial functionality in relevant industrial environments (warehouse pilots of current prototype). However, the pilots identified crucial areas for improvement. The EIC Accelerator project will advance the robot to TRL9, focusing on intelligent perception and AI-driven autonomy, enhanced elasto-kinematic control, intuitive human–machine interfaces, certified industrial production, and final pilot validation. The technology will unlock automation in dense, high-throughput environments such as e-commerce fulfilment, post-and-parcel handling, and micro-manufacturing - previously uneconomical for existing robots. Our goal is to reinforce Europe’s technological sovereignty in advanced manufacturing, contributing directly to the EU’s digital and green transition goals.

Keywords: robotics,warehouse automation,hybrid kinematics,motion control,ai enabled robotics,logistics automation
Circular Innovation for Recycling Complex Used Textiles (CIRCUT)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2400000.0
EU funding (EUR): 2400000.0
Participants: 1
Project status: SIGNED

The CIRCUT project (Circular Innovation for Recycling Complex Used Textiles) is an initiative led by RECYC’ELIT, a deeptech industrial startup. The project focuses on recycling hard-to-recycle polyester-based textiles using a unique chemical technology that operates at lower temperatures and atmospheric pressure, making it very energy-efficient. This innovative process allows for the recycling of chemically coloured and multi-fibre materials, transforming them into high-quality, low-carbon, and high added-value materials. The project aims to scale up from laboratory to industrial scale. The ultimate goal is to revolutionise the textile industry with an advanced fibre separation and recycled PET production technology.

Keywords: pet based textile recycling,polyester recycling
FOSTERING CIRCULARITY IN TEXTILE: INNOVATIVE INTEROPERABLE SOLUTIONS AND BEST PRACTICES FOR IMPLEMENTATION AND HARMONIZATION OF EPR SCHEMES (Circula-TEX)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Innovation actions
Countries involved: Italy,Belgium,Estonia,Netherlands,Spain,Denmark,Bulgaria,Germany,Switzerland
Call: Circular solutions for textile value chains based on extended producer responsibility (HORIZON-CL6-2024-CIRCBIO-01, 2024)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 6550877.5
EU funding (EUR): 5637370.0
Participants: 20
Project status: SIGNED

Circula-TEX, with its multidisciplinary approach, aims to support the EU Strategy for Sustainable and Circular Textiles by facilitating the redesign of textile value chains through the adoption of a circular approach and ensuring compliance with the expectations of Extended Producer Responsibility (EPR) schemes and European directives. The project will delve into the failures and gaps in the current textile value chain, particularly in terms of technological, environmental, economic, legal, and social aspects, and will explore the effectiveness of EPR schemes and other technological and non-technological measures to maximize the sustainability of the textile sector. The project will employ co-creation approaches to engage all stakeholders in the value chain and relevant case studies to develop actionable recommendations for circular textile management. These recommendations will include solutions to enhance the scalability of textile recycling and reuse through eco-design strategies, efficient systems for material composition identification and labeling to support textile collection and sorting, as well as traceability of information, and innovative approaches for reuse and waste treatment. Circula-TEX aims to provide evidence-based criteria for the harmonized implementation of EPR schemes and associated policies across the Member States. An innovative labeling system, in line with the Digital Product Passport and Eco-design for Sustainable Products Regulation directive(ESPR), will be developed to provide consumers, waste collectors, and reuse/recycling organizations with valuable practical information and promote reuse and the uptake of secondary materials in the market. The findings, initially applied and validated across four case studies, are expected to be expanded and replicated in various textile market segments and EU countries.

Keywords: textile industry,extended producer responsibility,eco modulation,sustainable textile,digital product passport,circular textile value chain,secondary materials,waste framework directive