Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
6G-Multiband Wireless and Optical Signalling for Integrated Communications, Sensing and Localization (6G-MUSICAL)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Smart Networks and Services
Action type: Research and Innovation actions
Partnership: SNS (JU-JTI)
Countries involved: Portugal,United Kingdom,Japan,Germany,Cyprus,Finland,Belgium,Romania,Switzerland
Call: Wireless Communication Technologies and Signal Processing (HORIZON-JU-SNS-2023, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 2933620.0
EU funding (EUR): 2858120.0
Participants: 11
Project status: SIGNED

6G-MUSICAL is a ground-breaking project that merges radio sensing and communication technologies to create new paradigms in RF communication. It aims to equip edge infrastructure nodes of 6G with integrated RF/radar-based radio-sensing elements that co-work with communication components. This enables localization, object tracking and 3D imaging, with cm-level precision and resolution. As such, the project will investigate new spectrally and energy efficient system architectures and signals, to facilitate high-rate communication across multi-frequency bands integrated with accurate sensing and localization. Compared to other joint communication and sensing research, 6G-MUSICAL stands out in two ways. First, it considers sensing for both connected and non-connected objects, which is important given the trend towards connecting everything. Second, it addresses the synchronization of edge nodes, which is critical to achieving extreme levels of accuracy and resolution. The project will combine optical and electronic technologies to generate precise and stable references, enabling a network of smart cooperative multi-static radars, within future 6G, bringing new services, high accuracy localization and high-resolution 3D object reconstruction. In the wireless domain, the project will define new waveforms suitable for radio-sensing and communications, exploit compressive sensing techniques and define cooperative multimode sensing and localization algorithms. In the network domain, focus will be on procedures for synchronization/calibration among edge nodes and on compression techniques to enable low overhead transport to a data fusion center of the collected information. The optical/electrical technology will develop and distribute the reference signals and will create novel antennas to address 6G requirements. Machine learning will be used to jointly optimize the system and services. Key technologies will be demonstrated in labs to meet a stringent set of predefined KPIs.

Keywords: radio sensing,positioning,joint waveforms for communications and sensing,multistatic radar,localization
Revolutionising allergies diagnostics with the next generation of ultra-sensitive highly multiplexed diagnostic tests based on micro-pearls (Nexdiag)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: France
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-05-01
End date: 2026-07-31
Duration (months): 39.0
Total project cost (EUR): 3628125.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The WHO predicts that half of the European population will suffer from allergies. Allergies are a growing burden for our society, our healthcare system and companies that have to take staff off work due to disabling symptoms. Thanks to fluorescent µpearls and the discovery of Quantum Plates, Nexdot is developing a highly multiplexed diagnostic test that will allow to assay IgE on 500 allergens (and up to 1000) at once using only one drop of blood. This innovation will revolutionize the way allergies are treated by reducing drastically the time to diagnostic and its associated cost (x10-20 reduction). Our technology could also be extended to serology tests, for detection of patient’s antibodies against infectious agents or cancer markers. It can be extended for global health for the easy and cost-effective detection of antigens as infectious or toxic agents in human, animals or environment for global health, or food for industry.

Keywords: allergy,serology,multiplexed diagnostic,quantum plates
3D silicon detector for imaging of diagnostic and therapeutic nuclear medicine radiotracers with outstanding efficiency and high spatial resolution. (Si3)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Prevention,  Diagnosis and T reatment of Human Diseases
Panel description: Medical technologies  and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions , pharmacology, preventative  medicine, epidemiology and public health , digital medicine
Countries involved: Sweden,Italy
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2024-11-01
End date: 2029-10-31
Duration (months): 60.0
Total project cost (EUR): 3351875.0
EU funding (EUR): 3351875.0
Participants: 2
Project status: SIGNED

This project aims to design, construct, and evaluate a novel instrument for molecular imaging of radioactive nuclides in the human body. The hypothesis is that, by using next-generation silicon sensors to measure each photon interaction and applying kinematic constraints, the incident photon direction can be calculated. Thus, we can remove state-of-the-art mechanical collimators. The main objective of this project is to explore the physical limits of efficiency and spatial resolution and evaluate the concept for this new technology in medical imaging applications. The new instrument should improve detector efficiency by about a factor of one million, reducing examination time from an hour to less than a second. The concept aims to overcome Compton cameras' shortcomings such as complicated geometries with low efficiency, that, despite several attempts, prevented this technique from going beyond an early prototype stage. The new sensor concept consists of a massive block of silicon built up from a multitude of sensors, with high resolution in space, energy and time and including signal shaping and data processing. The system will have orders of magnitude more read-out pixels than ever before in medical imaging. The system design and image reconstruction process are conceptually challenging, addressing several scientific problems at the component level such as pixel charge collection and capacitance, but also including image reconstruction from fragments of event circles, combinatorial problems involved with tracing each event to discern the correct order of interactions and to reject background events. Over a 10–20-year period, the technology could replace the current installed base, leading to significant impacts on adjacent research fields, such as drug development and targeted radionuclide therapy.

Keywords: molecular imaging,spect,single photon emission computed tomography,radiopharmaceuticals,targeted radionuclide therapy,compton camera,compton imaging,silicon sensors,photon counting,nuclear medicine,nuclear imaging
Expanding our understanding of human evolution through pleiotropy (Tied2Teeth)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Spain
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2022-11-01
End date: 2027-10-31
Duration (months): 60.0
Total project cost (EUR): 2252167.5
EU funding (EUR): 2252167.5
Participants: 1
Project status: SIGNED

Teeth dominate the fossil and bioarchaeological records because they consist mostly of inorganic material. Consequently, dental anthropology has long been essential in our investigation of the human past. Variation in the anatomy of teeth is instrumental for differentiating species, identifying biological affinities between populations, making inferences about dietary adaptations, and timing key developmental life stages. However, recent advances in genetics, genomics, and developmental biology undermine many assumptions built into anthropologists’ study of the dentition by revealing extensive pleiotropy—when one gene influences more than one anatomical structure simultaneously. However, this is not a setback but rather an advantage. In this project, we will use the pleiotropies that involve teeth to open windows to the evolution of human anatomies far beyond the dentition. I will employ three methodological approaches that utilize pleiotropy to probe different aspects of human paleobiology. The first approach will use quantitative genetic analyses to calibrate the extent to which cranial evolution is genetically correlated with dental evolution. In the second approach, we will employ large historical morphological datasets combined with the modern insight from genome-wide-association-studies (GWAS) to explore how the evolution of soft-tissue anatomy may have driven changes in the dentition. Finally, we will turn to the fossil record. Using traits that were defined using a pleiotropic approach, we will test the hypothesis that environmental selection influenced dental variation during two key time periods within the evolution of genus Homo. This project modernizes the study of the human past by incorporating the phenomenon of dental pleiotropy. By combining these three different approaches and a range of time scales, we turn the conundrum of pleiotropy into a powerful tool for studying human evolution.

Keywords: dentition,paleontology,quantitative genetics,human adaptation,hominid
Real-time Indication of Faecal pigments in Freshwater (RIFF)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-06-08
End date: 2026-06-07
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: SIGNED

WHO estimates that 2 billion people worldwide consume drinking water that has been contaminated with faeces, yet scientific testing for faecal contamination in water currently takes at least 10 to 24 h, as per UNICEF reports. Thus, there is an urgent need for methods that allow to unequivocally test drinking water quality on site, therefore significantly contributing to the United Nations’ Sustainable Development Goals, in particular to SDG 6 (access to clean water and sanitation). However, currently, no rapid, portable, sensitive and cost-effective method or device for the detection of faecal pigments outside of a lab is available. The proposed sustainable method to be developed in RIFF represents a shift from a faecal indicator bacteria (FIB) to a faecal indicator pigment (FIP) paradigm in faecal contaminant detection technology. This interdisciplinary project will demonstrate (1) a rapid and cost-effective sensory device for the real-time analysis of FIPs having as (2) a key element, a specifically tailored hybrid filter membrane for selective and sensitive FIP enrichment and detection (10 pg/L to 1 µg/L). Besides membrane tailoring for selective FIP capture, interfacial chemistry and assay integration will enhance the detection performance of a final device. The proposed method eliminates the need for solution-based FIP analysis, thus mitigating the technical issues associated with real-time water quality testing as well as bringing user-friendliness and operational stability. Hence RIFF will have a significant societal impact towards providing novel solutions for health challenges associated with drinking water contamination. The successful completion of the project will give me the opportunity to acquire multidisplinary skills in the field of sensor material development, device construction and rapid testing, which is necessary for establishing my future research career as an independent researcher in the field of water research & water quality monitoring.

Keywords: faecal pigments analysis,rapid analytical methods,hybrid membranes,chemically modified graphene oxide,fluorescence spectroscopy and water quality testing
EUropean Network for knowledge exchange and peer-to-peer learning between actors and stakeholders of the Horse sector to improve the resilience of equine farms (EUNetHorse)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Coordination and support actions
Countries involved: France,Belgium,Finland,Germany,Poland,Portugal,Spain,Romania,Switzerland
Call: Thematic networks to compile and share knowledge ready for practice (HORIZON-CL6-2022-GOVERNANCE-01, 2022)
Start date: 2023-03-01
End date: 2027-02-28
Duration (months): 48.0
Total project cost (EUR): 3037381.25
EU funding (EUR): 2999997.0
Participants: 15
Project status: SIGNED

The overall objective of EUNetHorse is to establish an active multi-stakeholder network in France, Portugal, Spain, Belgium, Germany, Romania, Poland, Finland, in order to increase the resilience and performance of their equine farms to face environmental, social, health, economic or political crises by widely disseminating practices, tools and solutions that improve (1) their resilience and socio-economic performance, (2) animal welfare and health on farms, and (3) the environmental sustainability of the sector. To achieve this, EUNetHorse will i) increase the flow of practical information between farmers in these 8 countries in a geographically balanced way and taking into account the differences between territories by structuring National-Horse AKISs in each country ii) collect and assess grassroots solutions and practices; disseminate best practices and solutions on the three thematic areas mentioned aboved replying to specific needs iii) achieve a greater user acceptance of the collected solutions and best practices through cross-fertilisation between all actors of the sector (horse breeders, advisors, trainers, technical experts, scientists, policy makers, sector representatives, etc. ) and all levels (local, regional, national and European) during exchange activities allowing peer-to-peer learning such as workshops, demonstration days, training and cross visits. v) maintain the practical knowledge in the long term - beyond the project period - by sharing the full set of project results on the EUFarmbook platform accessible to all, by training advisors and trainers during the project on these topics, by setting up a sustainable network of trainers and advisors who can continue to train equine farmers and disseminate these solutions using the training kit made available through their activities with equine farmers.

Keywords: equine farmers,advisors,trainers,resilience,performance,socio economy,welfare,sustainability,cost benefit,peer to peer learning,cross fertilisation,networking,multi actors,akis,europe
Next-Generation Indium Gallium Nitride Micro LEDs (InGaNious)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Sweden
Call: EIC Accelerator Open (HORIZON-EIC-2022-ACCELERATOR-01, 2022)
Start date: 2023-02-01
End date: 2025-06-30
Duration (months): 29.0
Total project cost (EUR): 3186833.75
EU funding (EUR): 2230783.63
Participants: 1
Project status: CLOSED

Our method of growing pure InGaN μLEDs is completely unique. We start with a layer of thin GaN on a substrate. This layer has the same high defect density that other existing technologies struggle with. Then we add a mask made of either silicon nitride or aluminum oxide introduced by us using a high-resolution lithography process. The mask contains tiny holes ca. 100 nm in diameter which become growth sites for intrinsically defect-free InGaN pyramids. These pyramids are then reshaped into truncated hexagonal pyramids, aka InGaN platelets that are just 700 nm wide (effectively a nanoLED) and contain the active micro LED structure after regrowth on the top c-plane of the InGaN platelets. We can already grow the μLEDs on 2” wafers on a sapphire substrate, and we are developing new methods to grow 4” wafers on a silicon substrate. Our KPIs (pixel size <1 µm, internal quantum efficiency >3.5%, FWHM <50 nm, etc.) already outcompete current commercial options for sub-2 µm-pixel size.

Keywords: micro leds,indium gallium nitride,semiconductors
Novel diffuse Optical method to combat skin color bias in non-invasive optical biomarker sensing devices such as pulse oximeters (NOBIAS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Ireland
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-03-01
End date: 2030-02-28
Duration (months): 60.0
Total project cost (EUR): 1582349.0
EU funding (EUR): 1582349.0
Participants: 2
Project status: SIGNED

During COVID-19, skin color bias in Optical Biomarkers Sensing (OBS) devices (e.g., pulse oximeter) was suspected to have contributed to the loss of lives in darkly pigmented people. The Continuous Wave (CW) technology used in these devices is limited in accuracy and results are biased by skin color and light scattering in tissue. NOBIAS aims to break through frontiers to create foundational multilayer fast Time Domain Diffuse Optical Spectroscopy (TDDOS) to eliminate color bias and inaccuracy shortcomings of current CW technology and revolutionize the future of bias-free, accurate optical biomarker sensing. To achieve this ambition, NOBIAS will create a multilayer TDDOS dynamic skin tissue model based on Monte Carlo to investigate the effect of skin type and anatomy on color bias, to optimize the concept, device and probe design to compensate and eliminate color bias and inaccuracies (WP1, Obj.1). 2 groundbreaking approaches (i) intermediate hybrid CW-TDDOS fusion approach (phase 1) is envisioned to compensate for skin color bias, followed by (ii) an ambitious new frontier fast TDDOS approach (phase 2) to eliminate color bias (WP2, Obj.2) and provide faster (100-250X), real time measurements at wearable footprint (100X). A first-of-a-kind compensation algorithm based on real-time instrument response function (IRF), and phantom arm aims to deliver groundbreaking accuracy (14X) (WP3, Obj.3). Early benchtop testing and feedback across work packages will mitigate risks of ambitious objectives. NOBIAS paradigm device/algorithm will be validated on tissue-mimicking phantoms and bias-free sensing will be demonstrated on blood biomarkers (haemoglobin (Hb, HbO), oxygen saturation (StO2, SpO2)) sensing at wrist location on healthy i) adults ii) infants (WP4, Obj.4). NOBIAS breakthrough lays the foundation for the world’s first bias-free and accurate OBS devices and sets its legacy to be the gold standard for bias-free clinical and personal biomarkers sensing applications

Keywords: time domain diffuse optical spectroscopy,near infrared spectroscopy,tissue optics,biomedical optics,biophotonics
Removal of microplastics from the environment using autochthonous wastewater-derived microbial consortia (REMIPLASWAS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-03-07
End date: 2025-03-06
Duration (months): 24.0
Total project cost (EUR): 181152.96
EU funding (EUR): 181152.96
Participants: 1
Project status: CLOSED

The accumulation of microplastics (MPs) in the environment poses a great threat to the biosphere. Known and demonstrated conventional methodologies used in the treatment of MPs in wastewater have several limitations. Therefore, there is the need to develop new eco-friendly, cost-effective biobased MPs (Polyethylene terephthalate-PET) removal strategies. Microorganisms can transform organic matter as well as remove pollutants through a chain of different catabolic reactions energized by the induction of non-stereoselective enzymes. Hence, this project will be the first attempt to deploy microbial autochthonous consortia as an eco-friendly remediation technique and strategy in the removal of MPs in the wastewaters. However, to overcome the limitations associated with cultivation and identification of MP degraders, I propose the use of a natural microbial consortium that harbours a plastic-degrading microbial community in wastewater after an enrichment process. Thus, in this project, an enhancement of microorganisms with catabolic capacity to transform MPs will be used for the development of a bio-based tailored technology, which represents the promising potential of this project. The overall objectives of this project are to: (1) characterize MPs in wastewater (2) isolate autochthonous consortium of MPs (PET) degraders in a short term enrichment experiment, study the microbial communities participating in MPs removal and identification of key genes in the catabolic process (3) select a microbial consortium with the ability to remove MPs and study of the fate of MPs in batch experiments (4) scale-up the process into a bench-scale bioreactor to develop a bioaugmentation technology with a microbial native consortium based on their ability to degrade MPs. (5) assess the toxicity of the resulting effluent after MPs process (6) verify the implementation and validate the design of the bioreactor, calculating the effectiveness of the equipment through a predictive model

Keywords: fungi bacteria consortium wastewater microplastics degradation