Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
World's first device-based treatment for small abdominal aortic aneurysms based on revolutionary new treatment paradigm (STAAART SmarT Abdominal Aortic AneuRysm Treatment)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open 2023 (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2024-01-01
End date: 2025-12-31
Duration (months): 24.0
Total project cost (EUR): 3999673.5
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

The Angiolutions device is a first-of-its-kind device stopping the life-threatening progression of small abdominal aortic aneurysm (AAA) – a pathological dilation of the aorta. Angiolutions’ award-winning & patent-protected solution leverages a fundamentally new understanding of AAA growth discovered by the founders at Stanford University. They showed that stiffness gradients between the compliant (healthy) aorta and the adjacent stiff (diseased) aneurysm serve as a motor for AAA growth. Based on this principle & together with key physicians, we developed a minimally-invasive, non-active aortic implant (class III). The nitinol-based device is positioned adjacent to the aneurysm sack via simple, catheter-based implantation. It is specifically designed to focally increase aortic stiffness in the compliant AAA neck region, thereby reducing stiffness gradients towards the stiff AAA sack that drive aneurysm growth.Hereby, we achieve a fast, low-risk, size-stabilizing treatment of small AAA.

Keywords: abdominal aortic aneurysm,healthy ageing
Optical Sequencing inside Live Cells with Biointegrated Nanolasers (HYPERION)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-08-01
End date: 2027-07-31
Duration (months): 60.0
Total project cost (EUR): 1577695.0
EU funding (EUR): 1577695.0
Participants: 1
Project status: SIGNED

Deciphering the code of life has sparked one of the biggest scientific endeavours in human history. Today, 18 years after the completion of the Human Genome Project, databases around the globe host over a million genomes. Surprisingly, one of the most important results that has emerged from this abundance of genetic information is how diverse and complex the processes are that control the constant regeneration, preservation, and adaptation of life. Understanding the relationships between cellular genotype and phenotype is therefore of fundamental importance in developmental biology as well as in the biomedical sciences. Many molecular mechanisms that shape our body during our life are still largely un-known due to the limitations of current sequencing technologies which can only glimpse a single moment in time. In stark contrast, biological cells constantly monitor their function and can, if needed, quickly adjust to changes in their environment by the transfer of information between the nucleus and the cellular protein machinery in form of RNA. Yet despite their essential function no technique can record these highly dynamic profiles of intracellular RNA. Gathering transcriptomic profiles from intact cells and within living organisms therefore represents a major challenge for any existing sequencing and sensing technology. Here, HYPERION introduces an entirely new concept of optical sequencing to detect transcriptomic information in real time and inside living biological cells. It is based on ultra-sensitive plasmonic nanolasers that combine recent advancements in extreme optics with a new concept to spatially confine RNA molecules. These lasers could be adapted to sense other biomolecules and mark the beginning of a new era in intracellular biosensing. Like the titan god of light, supposed to bring mankind the gift of sight, HYPERION will exploit the unrivalled precision of laser light to uncover the processes that shape life on the molecular level.

Keywords: optical sequencing,rna sequencing,live cell sequencing,nanolaser,laser spectroscopy
UR4energy: Underwater Robots for efficient ocean energy harvesting (UR4energy)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Norway
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2024-09-01
End date: 2026-02-28
Duration (months): 18.0
Total project cost (EUR): 192857.14
EU funding (EUR): 150000.0
Participants: 3
Project status: SIGNED

The renewable energy input in the grid is not sufficient to cover the European energy demand, which largely still depends on fossil fuels. To reach the goal of climate neutrality by 2050, Europe needs to diversify and improve the adoption of renewable energy technologies. A yet-untapped source of energy can be found in the ocean. While wave and tidal energy have been explored, the reliable and predictable vortex wake energy has not been harvested yet as a renewable energy source. UR4energy will tap into this energy source by developing an efficient way to harvest it by using Underwater Robots. In this project, Prof. Pettersen will prove the technical and commercial feasibility of an underwater robot for ocean energy harvesting. Prof. Pettersen’s group will integrate the expertise of two partners, i.e., Inventas AS and NTNU Technology Transfer AS, for the development of the prototype and the monitoring of the patent landscape, respectively. UR4energy contributes to the ocean energy market, one of the fastest growing renewable energy markets (CAGR 2022-2030 = 33.5%) with a versatile technology that has the potential to support the EU’s independence from fossil fuels, while contributing to research on robotics and autonomy for underwater robots.
Inverse thermal-wave modelling of heat transfer in biological tissues (IWFM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 1
Project status: SIGNED

Many practical applications related to biomedical, wind, seismic or noise excitations require reconstructing structural properties from the knowledge of some appropriate output responses. In the field of biomedical engineering, the importance of the topic can easily be demonstrated by the significant impact on organs malfunctioning caused by abnormalities within biological tissues, such as tumour formation and growth. These disorders must be detected and treated early in order to save lives and improve the general health. Understanding the heat transfer in biological tissues and, in particular, the determination of tissue’s properties and the blood perfusion rate are important yet difficult tasks, and, in such sense, this project will seek to maximise the efficiency in providing rapid, intelligent and cost-effective solutions to unexplored impactful challenges. To contribute to achieving such an admirable goal, this proposal aims to accomplish, for the first time, the nonlinear identification of biological properties in thermal-wave heat transfer using inverse methods that are non-invasive and non-destructive. More concretely, reconstructions of the time- or space-dependent blood perfusion coefficient in the hyperbolic thermal-wave equation from transient measurements of the temperature at tissue’s boundary will be investigated. This analysis requires understanding the ill-posedness of the new inverse nonlinear problems for hyperbolic partial differential equations that are formulated to govern the heat propagation in biological tissues. Proving the uniqueness and stability of solution using the technique of Carleman estimates will be challenged, and developing globally convergent and stable methods of reconstruction will be attempted. Moreover, to add practical significance to the research in a way that may ultimately help to monitor and control the integrity of biological tissues, noisy numerically simulated and experimentally measured data will be inverted.

Keywords: inverse problems coefficient identification partial differential equations regularization thermal wave modelling
Sustainable, Usable and Visible Digital Cultural Heritage: Twinning for Excellence (DIGHT-Net)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Panel: Social Sciences and Humanities
Countries involved: Estonia,Italy,Netherlands,Finland
Call: Twinning Bottom-Up (HORIZON-WIDERA-2023-ACCESS-02, 2023)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 1498026.58
EU funding (EUR): 1498026.58
Participants: 4
Project status: SIGNED

The objective of the DIGHT-Net is to enhance research capacity, broaden the research partnership and increase the visibility & attractiveness of Tallinn University (TLU) in digital cultural heritage studies. To mobilise and amplify digital cultural heritage research locally, nationally and internationally, ensure sustainability and maximise the impact, the joint research hub of Digital Cultural Heritage studies (DIGHT-Hub) will be co-established at the TLU’s School of Humanities. The project shall prototype a Twinned Digital Archive of Juri Lotman and Umberto Eco, and build a semiotic theory of digital cultural heritage, based on the work of Lotman, Eco and other scholars. The objectives will be achieved through networking and collaboration activities with internationally-leading research institutions: The University of Bologna (UNIBO), the University of Amsterdam (UvA), and the University of Turku (UTU). Not only do these partners have a high level of scientific capacity and international reputation, but they are also well-integrated into the international research and collaboration networks and have a proven track record in early-stage researcher development and research management. The experience, knowledge and authority of leading European competence centres in archival and heritage studies, digital culture studies and memory studies will provide perfect pathways for TLU to raise the bar for excellence, increase attractiveness and retention of research talents, modernise the approach to participation in Horizon Europe competitions and consequently achieve a long-lasting contribution to the European cultural heritage and its digital transformation.

Keywords: digital archive digital data juri lotman umberto eco digital cultural heritage intellectual history
Development of Ultrathick Laser Ablation for Ultrathick Electrode Processing (UltraThick Las)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 1
Project status: CLOSED

The proposal aims to improve the electrochemical power performance of NMC based generation 3b batteries through the development of ultra-thick electrodes. This will be done through the following objectives: 1.) Increased power performance in ultra-thick-film electrodes through the development of 3D electrode architectures 2.) Correlation of lithium-ion diffusion characteristics with 3D electrode architectures and related electrochemical performances through simple modeling via Penetration Depth Model (PDM) 3.) Establishment of Nuclear Magnetic Resonance (NMR) techniques and Laser-Induced Breakdown Spectroscopy (LIBS) as complementary methods for identification of lithium-diffusion pathways in 3D electrodes 4.) Realization of optimized 3D electrode architectures for anodes and cathodes prepared with environmentally friendly water-based slurries. This will be done through a multi-discipline approach that involves the following techniques and principles: laser based ablation, ablated materials recycling, water based formulation, Nuclear Magnetic Resonance Imaging and Penetration Depth Model. Laser ablation will be used to fabricate 3D microstructures in ultra-thick NMC (nickel-manganese-cobalt oxide) based electrodes to increase the electrode porosity and help attain optimum cell power density of upto 209 Wh/kg at 2C cycling. The optimization of the 3D ablation patterns will be done through the correlating the electrode's power performance with its diffusion coefficient (determined via NMR imaging), electrode parameters and effective porosity via the PDM. Water based slurry formulation and ablated materials recycling will be done in conjunction to decrease production cost and allow laser ablation processing for electrodes closer to "demonstration pilot level" (TRL 5-6). Upon success of the project, NMC based generation 3b batteries can be realized for electric vehicle applications and we could reach on of the goals stated in Horizon 2021's Work Program.

Keywords: battery,ultrathick electrodes,laser ablation,nucleic tagging,imaging nmr,fast charging,3d electrode architecture
Advanced Software Tools for JavaScript Developers (PAWTOOLS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Denmark
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-05-01
End date: 2023-10-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Modern web-based software uses the JavaScript programming language together with the Node.js framework and extensively rely on freely available third-party software libraries that provide common functionality. These libraries are continuously improved, and new versions are released frequently. This massive reuse of libraries is essential to the productivity of software developers, however, the dependence on other people's libraries opens the door to security vulnerabilities and programming errors that may have severe consequences to the applications and end users. With current technology, it is extremely difficult for the software developers to adapt programs to breaking changes in libraries, avoid unintended breaking changes, and investigate the possible consequences of security vulnerabilities in libraries. The ERC project PAW has delivered a range of novel program analysis techniques that can help JavaScript programmers by automating these complex tasks. The analysis techniques have been implemented as prototype software tools, and preliminary experimental results have demonstrated that they are effective on real-world software. The proposed project, PAWTOOLS, aims to explore the commercial and innovative aspects of these scientific results, by further developing the prototype tools into commercial products, performing more extensive evaluations of their effectiveness, and engaging with potential users and industry partners.
Understanding the Role of Diversity in European Research (URDER)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-06-01
End date: 2024-05-31
Duration (months): 24.0
Total project cost (EUR): 183600.96
EU funding (EUR): 183600.96
Participants: 1
Project status: CLOSED

The recent intensive sociopolitical debates on racism and the colonialism, which created a wave of protests across the Global North, has broken the ordinariness of the racial status quo endemic to the modern social institutions. In academia, it has enforced a series of initiatives, asking for reconsidering curricula and diversity quotas. The URDER project takes a step back from these societal debates to understand how practices of diversity are understood and applied by those who have a central impact on academic knowledge production and science more generally: the reviewers of academic grants. By studying the evaluation practices of the review panelists of the European Research Commission grant awards, the project will explore how scientific excellence is linked with diversity practices in the European research space. Bringing together (a) science policy studies, (b) cultural sociology, and (c) postcolonial critique, the URDER project seeks to investigate how the European academic elites in social sciences and humanities understand the role of decolonial, anti-racist, and diversity initiatives in European research. The proposed project will allow for training the Fellow in science policy, research management, and research evaluation while the Fellow will offer her valuable knowledge in postcolonial theories, feminist epistemology, and intersectionality. To provide conceptual overlaps between these fields of research will allow for critical assessment of diversity initiatives and propose effective solutions to address diversity in academia.

Keywords: decolonization,diversity,sociology of academic work,cultural sociology,postcolonial theory
High performing electrically rechargeable zinc-air batteries for sustainable mid-term energy storage (HIPERZAB)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Spain,Norway,Italy,Türkiye,Germany
Call: EIC Pathfinder Challenge: Mid to long term and systems integrated energy storage (HORIZON-EIC-2022-PATHFINDERCHALLENGES-01, 2022)
Start date: 2023-10-01
End date: 2027-09-30
Duration (months): 48.0
Total project cost (EUR): 3939947.5
EU funding (EUR): 3939947.5
Participants: 7
Project status: SIGNED

Energy storage is critical for the EU energy system to reach a large renewable energy share, climate neutrality, and affordable energy costs. Currently available energy storage solutions suffer from limited storage time, the use of toxic/flammable components, large amounts of critical raw materials (CRMs), and high costs that limit their large market deployment. Metal-air batteries present several advantages like cheap and abundant active materials (e.g., zinc + air), and high gravimetric energy density together with long-term stability; but, even in its more mature configuration, they cannot guarantee storage times > 4-12 h, and the present mechanical recharging concepts drastically increase operation and maintenance costs. HIPERZAB will design and validate at lab scale, for the first time ever, an Electrically Rechargeable Zinc-Air Battery (ERZAB) to enable breakthroughs in cyclability, storage time, costs, and life cycle design ideal for mid-term storage (days/weeks) to be coupled with renewables and electrolysers. To reach this goal, HIPERZAB will develop three innovative components: (i) a 3D porous Zn/biopolymer composite anode, (ii) an eco-friendly bilayer gel electrolyte based on naturally occurring precursors, and (iii) a CRM-free cathode based on high entropy oxides (HEOs). These components will be integrated into a single device proposing a radically new battery design that enables the water/air management control during cycling and the durability/performance of materials and components. To shed light into the research challenges, HIPERZAB will further focus on unraveling the correlations between materials, operating conditions, and electrochemical phenomena upon cycling through operando characterisations and multiscale modelling. HIPERZAB's developments will be continuously guided by life cycle and circular economy approaches to ensure sustainable end-of-life options.m

Keywords: electrically rechargeable zinc air battery crm free biopolymer operando characterisation multiscale modelling circular economy,mid term storage
Travelling Intelligence Against Crime and Terrorism (TENACITy)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Fighting Crime and Terrorism
Action type: Innovation actions
Countries involved: Luxembourg,Greece,Germany,Malta,Czechia,United Kingdom,Cyprus,Moldova, Republic of,Italy
Call: Terrorism and other forms of serious crime countered using travel intelligence (HORIZON-CL3-2021-FCT-01, 2021)
Start date: 2022-09-01
End date: 2025-08-31
Duration (months): 36.0
Total project cost (EUR): 5324436.25
EU funding (EUR): 4439136.25
Participants: 19
Project status: SIGNED

LEAs use the data in their information systems as their basis for making decisions that affect the safety of European citizens. According to a recent report of the European Court of Auditors on the EU Information Systems use, it has been found out that individual countries have different perception and methodologies on how data management should be addressed; officers from LEAs have stated that not all datasets are included in their systems, while other data is either not complete and accurate or not entered in a timely manner. The same report states that there are regulatory and “cultural” issues, according to which some countries do not make all the functions offered in the central EU systems available through their national systems. TENACITy envisions to address these challenges by proposing a 3-pillar approach: (a) Modern and effective tools for exploitation of travel intelligence data by security authorities: TENACITy proposes an interoperable open architecture for the integration and analysis of multiple transactional, historical and behavioural data from a variety of sources, by exploiting game changing digital technologies; (b) Training and sensitisation of LEAs’ personnel: TENACITy envisions the design of a “living lab” to be established to organise hackathons, workshops for all relevant stakeholders who would benefit from the use of passenger data and digital technologies proposed; (c) Holistic approach to crime prevention: TENACITy vision is to implement and demonstrate a Travel Intelligence Governance Framework that will incorporate a holistic approach to crime prevention, will ensure that the proposed digital technologies will support the identification of the modus operandi of criminal and terrorism organizations and will include policy makers in the governance process, examining how the new tools will provide new capabilities to shape the regulations.