Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Generative Relationships Output Unambiguation via Networks of Deterministic Evidence Derivatives - GenAI framework for evidence-based knowledge extraction in highly regulated industries. (GROUNDED)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 12.0
Total project cost (EUR): 500000.0
EU funding (EUR): 500000.0
Participants: 1
Project status: CLOSED

GROUNDED (Generative Relationships Output Unambiguation via Networks of Deterministic Evidence Derivatives) solves generative AI's critical trustworthiness gap by transforming opaque LLM extraction into verifiable, auditable knowledge modeling. While current GenAI systems produce black-box outputs vulnerable to hallucinations, GROUNDED introduces deterministic validation that makes AI-extracted information defensible for high-stakes applications in healthcare, legal, regulatory and scientific domains. Our breakthrough extracts documents as redundant relational networks where the same facts must emerge through multiple pathways. The system performs deterministic consistency validation: if we’re analyzing the Study S and it mentions Gene X, and the graph shows Gene X links to Disease Y in this study, then Study S must also link to Disease Y - otherwise the model is internally contradictory. This logical validation automatically flags inconsistencies for human review. Every extracted relationship anchors to specific source passages. GROUNDED performs grounding verification to catch hallucinated citations, evidence strength scoring to identify weak claims, and coverage analysis to surface under-evidenced assertions. Every claim traces to verifiable quotes, contradictions are automatically surfaced, and reviewers can audit extraction step-by-step. Currently deployed with biotech partners for scientific relationship extraction, GROUNDED addresses EU AI Act requirements: transparency through full audit trails, accountability through deterministic validation, human autonomy through flagging rather than replacing judgment, and data quality through multi-perspective consistency checks. GROUNDED establishes verification infrastructure that unlocks GenAI adoption where accuracy is legally, medically and scientifically mandatory. By making AI extraction provably reliable, we enable European leadership in ethical, accountable generative AI for knowledge-intensive industries.

Keywords: truth grounded ai,verifiable ai,explainable ai,genai for regulated industries,knowledge extraction,knowledge graphs and information retrieval,unstructured data mining
Using thermal limits to understand community response to climate warming (ClimateCountDown)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental B iology, Ecology  and E volution
Panel description: For all organisms : Ecology, biodiversity, environmental change , evolutionary biology, behavioural ecology, microbial ecology , marine biology, ecophysiology, theoretical developments and mod elling
Countries involved: France
Call: ERC CONSOLIDATOR GRANTS (ERC-2024-COG, 2024)
Start date: 2025-04-01
End date: 2030-03-31
Duration (months): 60.0
Total project cost (EUR): 1998612.5
EU funding (EUR): 1998612.5
Participants: 1
Project status: SIGNED

When will communities reach their upper thermal limits (i.e., their climate countdown)? A key challenge for ecology and conservation only to be addressed by understanding the biological processes driving community thermal limits and assessing how fast warming actually pushes communities to these limits and thus increases their vulnerability. The difference between upper thermal limit and habitat temperature is widely used to predict thermal vulnerability. Yet, existing models are mostly limited to single species and neglect key processes such as species interactions. To predict the thermal vulnerability of multi-trophic communities, we need to scale up thermal limits from species to community. This can only be done by answering four key questions: i) How do species interactions impact individual thermal limits? ii) How do acclimation and evolution influence community thermal limits? iii) How do temperature impacts on food web structure and community composition influence community thermal limits? iv) How does spatial heterogeneity in warming rates affect community’s vulnerability? To address these four key research questions I propose a novel integrative approach combining semi-natural aquatic experiments, temperature-dependent community models, analyses of 200 lake food webs and climatic projections. This ambitious research programme will evaluate how the evolutionary dynamics of each species, their interactions and food web structure collectively contribute to defining community thermal limits. It will predict the climate countdown of lake communities and test if the latter informs of biodiversity losses induced by climate warming. This project will provide unprecedented insights on community thermal vulnerability by linking ecophysiology with community ecology. By uncovering the mechanisms of community thermal limits it will contribute to understanding how communities respond to climate change and provide a new means of predicting the future of biodiversity.

Keywords: thermal vulnerability,community ecology,climate change,food webs,thermal safety margin,aquatic ecology
Harmonization of Advanced Materials Ecosystems serving strategic Innovation Markets to pave the way to a Digital Materials & Product Passport (DigiPass)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Coordination and support actions
Countries involved: Germany,Luxembourg,Austria,Belgium,Norway,Greece,United Kingdom
Call: Coordination and knowledge sharing across materials development communities (CSA) (HORIZON-CL4-2023-RESILIENCE-01, 2023)
Start date: 2024-04-01
End date: 2027-03-31
Duration (months): 36.0
Total project cost (EUR): 1979030.58
EU funding (EUR): 1874298.44
Participants: 12
Project status: SIGNED

The overarching objective of DigiPass is to enhance the digital maturity of the European communities that develop materials and intermediate products. The project will develop recommendations and clear routes toward digitalized circular business models. The overarching key result of DigiPass is to create a sustainable platform which includes support for Digital Materials & Product Passport and for collaborative innovation-by-design processes in a circular economy served by advanced materials. A business model for operating such a platform completes the overarching objective. DigiPass is harmonizing and synergizing collected materials data sources and digital infrastructures. This will enable interoperability of data exchange, and standardization of advanced materials knowledge representation at all maturity levels. Accelerating the design, development, and production of advanced, safe, and sustainable chemicals and materials, as they are necessary for innovative products, calls for a collaborative approach involving different stakeholders to support durability, repair and overhaul, reuse, and recyclability of products. DigiPass project impacts all materials development communities over the whole circular value chain.

Keywords: sustainability digital product passport digital maturity enhancement bridging communities data and knowledge sharing businesses model digital transformation
A NOVEL CLICK-CHEMISTRY-BASED, UNIVERSAL RADIOLABELLING PLATFORM REVOLUTIONIZING THE GENERATION OF THERANOSTIC RADIOPHARMACEUTICALS (TETRAKIT)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Denmark
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 36.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

TetraKit Technologies (TT) is developing the TetraKit Platform, a universal radiolabelling platform that enables the synthesis of novel therapeutic and diagnostic (theranostic) radiopharmaceuticals (RPs). By overcoming the limitations of currently available radiochemistry solutions, TT will address the unmet need for an innovative approach that makes radiolabeling, specifically with radiohalogens, simple, rapid, effective and scalable. Based on an ultrafast next generation tetrazine ligation and linker technology, the TetraKit Platform allows labelling of any biomolecule (target vector) with any radiohalogen or radiometal, according to a versatile ‘plug-and-play’ principle. As such, TT will facilitate unleashing the full potential of novel theranostic RPs to serve the need of millions of cancer patients worldwide. To validate the TetraKit Platform, TT seeks EIC Accelerator blended financing to advance the clinical development of the lead asset emerging from the platform, 131I-DualFAPi, an iodine-131-labelled therapeutic RP that targets the fibroblast activation protein (FAP) – THE ‘next billion-dollars theranostics target’. Initially to be developed for the treatment of metastasized Triple Negative Breast Cancer (TNBC), an aggressive type of cancer with poor survival chances, TT’s lead asset will be the first radiohalogenated FAP-targeting therapeutic RP in clinical development, made possible by the TetraKit Platform. Completion of a Phase 1/2 program in TNBC patients will present a significant value inflection point for TT, which is anticipated to result in a strategic partnership for the final development and commercialization steps. Successful development of 131I-DualFAPi will be an essential milestone that will allow TT to fully exploit the TetraKit Platform, bringing immense commercial and societal value.

Keywords: radioligand therapy,theranostics,radiolabelling platform,cancer
4D Scavenger: the first technology to recover valuable and hazardous metals from industrial wastewater cost-efficiently on a large scale (4DScavenger)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Finland
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

>90% of dissolved metals are removed from circulation. 500 000 tons of hazardous heavy metals released to the environment each year. €50 billion worth of valuable metals such as gold, silver, copper, and platinum dumped every year in the growing mountain of electronic waste that pollutes the planet. €1 trillion worth of metals dumped as mining waste, with €20 billion added each year. These are just a few examples that illustrate how the world is losing valuable resources and polluting the Earth simply because industrial companies lack proper tools for metal recovery from wastewater. Today’s prevailing practice is to achieve minimal compliance with regulations by purifying the wastewater so that most of the dissolved metals, especially those defined as Critical Raw Materials are unrecoverably wasted. But if we want to achieve a circular economy and ensure sufficient supply, neglecting the resource recovery opportunities arising from improved wastewater management is nothing less than unthinkable. To address this challenge, we have developed 4D Scavenger, a novel system for selective recovery of valuable and hazardous metals from industrial wastewater. Compared to existing solutions, our technology combines unprecedented selectivity with faster reaction kinetics. This reduces the cost of metal recovery by up to 10x and thus makes the recovery of metals financially feasible for more types of metals, industrial processes, and smaller companies. We achieve this with a completely new metal recovery technology based on chemically functional porous filters. The technology uses the selective laser sintering (SLS) 3D printing technique to print the filter-like 4D Scavengers using (1) polymer powder such as PA12 that form the porous structure and (2) chemically active components such as chelating resins, ion exchange resins, adsorbents or molecular compounds that bind the desired metal ions to the 4D Scavenger.

Keywords: metal recovery,water purification
ELVER-CHECK: Well-grounded Lightweight Assurance for Critical Systems Software (ELVER-CHECK)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: United Kingdom
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2024-10-01
End date: 2026-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Computer systems have become critical to modern society, but they are pervasively subject to security flaws and attacks, with large-scale exposures of confidential data, denial-of-service and ransom attacks, and the threat of nation-state attackers: they are trusted, but are far from trustworthy. This is especially important for the systems software enforces what protection, eg the hypervisors that use the underlying hardware to isolate components from each other. ERC AdG ELVER has developed mathematical models of the *systems features* of the underlying hardware: working with Arm to characterise virtual memory, instruction/data cache maintenance, and exceptions. This opens up a new possibility: using those not just for correctness proof (which remains challenging), but also for *lightweight methods to improve the assurance of critical systems software*, by checking that such software obeys the subtle disciplines required by the hardware. Targets include the pKVM hypervisor being developed by Google to protect sensitive data on all Android phones, and similar hypervisors for the Cloud. Building on experience with a prototype checker, which has already found subtle bugs, ELVER-CHECK will prototype, assess, and demonstrate how to use executable checkers based on our mathematical models of systems architecture to improve conventional development of critical systems software, to increase assurance that it provides the intended security, at lower cost than full verification. ELVER-CHECK thus addresses an important aspect of the societal problem of the pervasive insecurity of our critical software infrastructure. This is a new opportunity: conventional software testing, analysis, and verification methods assume that memory is a simple mapping from locations to values, but they are oblivious to the subtle ways in that is simply not true for systems software, and to the disciplines that it must follow to actually enforce the intended security properties.
Early wildfire detection using AI and IoT network of sound detectors for climate resilience (Firewave)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 3500000.0
EU funding (EUR): 3500000.0
Participants: 1
Project status: SIGNED

Firewave is an innovative technology company dedicated to mitigating one of the most pressing environmental challenges of our times: the increasing threat of wildfires. Founded by Dr. Jenia Yurkovsky and Eduard Grinberg, Firewave combines advanced expertise in physics, computer science, and software engineering to develop a pioneering early wildfire detection system. Our vision is to revolutionize wildfire management through proactive early detection, leveraging cutting-edge technology to prevent minor fires from becoming catastrophic events. At Firewave, we are driven by a mission to safeguard communities, ecosystems, and economies from the devastating effects of wildfires. Our ambition is to scale up by deploying our fully automated, AI-enhanced network of IoT sensors which are recognizing wildfires across high-risk areas globally. Our IoT network is designed to identify the unique sound signatures of wildfires at their inception, enabling rapid response and significantly reducing the impact of fires. The vast majority of wildfires are caused by human activities. We believe that through the sophisticated deployment of an IoT network of detectors, covering areas with a high probability of ignition, our system will help prevent the spread of wildfires. Initially, our focus is on enabling medium-sized businesses located near forests to respond rapidly in the event of a nearby fire outbreak. However, our vision extends to covering large, forested areas, aiding humanity in adapting to the increasing reality of wildfires. Our ultimate goal is to be part of a holistic solution for wildfires, initiating the suppression of small fires to prevent them from spreading and evolving into full-blown wildfires.

Keywords: climate adaptation,extreme weather events,wildfires,iot,artificial intelligence,smart edge,disaster preparedness systems,fire prevention,remote sensing
Quality of Life in Oncology: measuring what matters for cancer patients and survivors in Europe (EUonQoL)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Cancer
Destination: Cancer
Action type: Research and Innovation actions
Countries involved: Italy,Denmark,France,Germany,Norway,Belgium,Netherlands,Estonia,Austria,Romania,United Kingdom,Spain,Bulgaria
Call: Develop and validate a set of quality of life and patient preference measures for cancer patients and survivors (HORIZON-MISS-2021-CANCER-02, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 10607311.01
EU funding (EUR): 10607311.0
Participants: 27
Project status: SIGNED

EUonQoL aims to develop, pilot and validate the EUonQoL-Kit, a patient-driven, unified system for the assessment of quality of life (QoL) based on evaluations and preferences of cancer patients and survivors. The EUonQoL-Kit will be developed from a patient perspective, administered digitally, available in the EU27 and Associated countries languages, and applicable in future, periodic surveys to contribute to the EU’s mission on cancer. At the core of the EUonQoL there is the adoption of a multistakeholder, co-design methodology, engaging patient representatives, healthcare professionals, administrators, policymakers, and citizens in all project related activities. Existing QoL tools will be reviewed, scoping all relevant sources. This review will be used in the context of the codesign consensus with stakeholders’ and patients’ preferences to identify gaps and establish all QoL dimensions that are relevant from the perspectives of patients, clinicians, and society. A multidisciplinary panel of leading experts will develop the EUonQoL-Kit to be validated in a digital pilot survey of 4,000 patients and survivors enrolled through a network of EU cancer centres. An analysis of factors potentially impacting QoL, will also be performed. EUonQoL will explore strategies for the implementation and exploitation of the EUonQoL-Kit, while coordinating a QoL-Patient-Centred Care (PCC) cluster across Cancer Mission projects to develop a system-wide PCC policy, built on sustained stakeholder engagement and targeted outreach, as the basis for routine QoL data collection. EUonQoL is composed of research institutions, cancer centres, as well as scientific, professional, and patient representative organizations involved in cancer research, all with extensive experience and robust scientific background in developing self-reported QoL measures. This partnership fuels the ambition of EUonQoL to translate QoL data into future changes in cancer care policy and clinical practice.

Keywords: health related quality of life,cancer,survivorship,palliative care,electronic patient reported outcome measures eproms,participatory research,psychometric validation,cancer related policies
Integrated Pathways: Advancing Safe and Sustainable by Design Material Innovation through Collaborative Wisdom (DESIDERATA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Innovation actions
Countries involved: Luxembourg,Italy,Greece,Sweden,Spain,Cyprus,Belgium,Austria,Germany,Portugal,Finland,France,Switzerland
Call: Development of safe and sustainable by design alternatives (IA) (HORIZON-CL4-2024-RESILIENCE-01, 2024)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 11956540.0
EU funding (EUR): 10678045.0
Participants: 16
Project status: SIGNED

The aim of DESIDERATA is to test and validate the the EC’s SSbD framework on selected industrial Use Cases that are already at TRL4 and which will aim at substituting Substances of Concern (SoC) with surfactant, plasticising and flame retardant properties. The twofold aim will firstly generate a remarkable impact, by advancing industrial value chains in the domain of construction, injection moulding, 3D printing, etc., by providing tangible advancement for SoC substitution for which there are no currently available solutions on the market. Secondly, the lessons learnt will support policymakers in continuing shaping the SSbD framework, improving its applicability and fostering its wider application in the European chemical and material manufacturing sector. To better track the progress of the project, 5 objectives have been proposed linked to the expected outcomes of the project and the scope of the topic: Obj1. Demonstration and proof of concept of the SSbD framework, achieving policy engagement; Obj2. Development of new SSbD compliant substances and materials; Obj3. Enhancing interoperability for data sharing across value chains; Obj4. Promoting safer and sustainable substances across value chains; Obj5. Maximising the impact of the project: A Collaborative Approach with Industry and Citizens. To achieve the objectives, DESIDERATA will cover a period of 48 months, and its performance will be structured into 9 Work Packages (WPs). These include the project consortium management (WP1), supported by the interoperability and data management (WP7), the stakeholder and policy engagement (WP8) and the dissemination & communication (WP9) of the results obtained. The scientific and technical activities are undertaken in WPs 2 to 6, which include the Use Cases design and implementation (WP2), Sustainability Assessment (WP3), Environmental Safety (WP4), the SSbD framework assessment, demonstration and refinement (WP5) and the Innovation management (WP6).

Keywords: safe and sustainability by design,nanomaterials,flame retardants