Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Seeing Like A City (SLAC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United States,Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-09-01
End date: 2028-08-31
Duration (months): 36.0
Total project cost (EUR): 265099.2
EU funding (EUR): 265099.2
Participants: 3
Project status: SIGNED

Seeing Like a City (SLAC) metaphorically assumes the city’s perspective, to explore visual media and filmmaking’s potential for knowledge production on cities and civic action within them. Intended as the entanglement of relations among human and non-human populations, it addresses existing vision problems within urban studies and planning. The project pursues an in depth critical study and structured integration of audiovisual methodologies in urban studies, to see how they can be key sites of urbanism in the making and produce change in the field. Capitalising on the generative intersections between filmmaking and urban studies, it seeks to visualize multiple, but often unseen elements, of city-making. In so doing, it aims to decolonize urban studies and re-politicize planning. It will focus on the specific declination of unseen that has to do with the city–nature nexus towards a more-than-human frame for urban studies. It will rely on sensory ethnography, affective multi-modalities in storytelling and participatory and collective filmmaking as applied at the Sensory Ethnographic Labs and the Film Study Center (FSC) at Harvard. Inspired by efforts to redefine urban studies through de/post-colonial notions and approaches, it will involve a secondment at the (C)artography Lab at Hamburg Universität (UUH). While there, the project will design an audiovisual work that I will develop during the return phase to Italy’s Department of Architecture and Urban Studies- DAStU at PoliMI, which will be the pilot project of a new audiovisual urban lab which will be born at DAStU thanks to the MSCA post-doc grant. The project’s novelty lies in this critical and action-oriented transdisciplinary aspect, mobilizing processes of radical openness (Sennett, 2018) and exchange between research in urban studies and audiovisual production as a potential tool of city-making, intended as that specific city design philosophy aiming at tuning the contemporary to the future (Laundry, 2009).

Keywords: audio visual art applied to urban studies experimental filmmaking innovative methodologies decolonial turn human and non human nexus environmental justice
Neural algorithms and representations of flexible behaviour (NARFB)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2025-11-01
End date: 2030-10-31
Duration (months): 60.0
Total project cost (EUR): 1486863.0
EU funding (EUR): 1486863.0
Participants: 1
Project status: SIGNED

Humans and other animals learn from experience and generalise it to new situations. This generalisation permits rich inferences from sparse data and building novel plans in the face of new obstacles. Yet our understanding of the neural mechanisms underpinning flexible behaviours is limited to simple situations such as spatial learning and only in the hippocampal formation. Flexibly behaviour and generalisation is much more than just space and the hippocampal formation – it is for any structured knowledge. Flexible generalisation lets you know that presents should be wrapped before being opened, in the same way as knowing that you can only vote if you are already registered. Such structured knowledge, and their corresponding tasks, are often hierarchical, compositional, and require inferences., yet we have little understanding of the neural mechanisms of hierarchical, composition, or inference. This grant aims to build an understanding of the underlying neural algorithms and representations permitting these cognitive functions. By combining modelling and theory, we will investigate the optimal neural representations and algorithms for solving these tasks and relate them to prefrontal cortex and the hippocampal formation. We will use recurrent neural networks trained to learn and generalise on structured tasks. Furthermore, we will understand these systems theoretically - providing a mathematical formalism for optimal neural representations and algorithms that can explain when and why neural systems learn different representations and algorithms. We will collaborate with experimentalists to test model and theory predictions. Lastly, we will use the understanding gained from neuroscience tasks to build bridges between natural and artificial intelligence. Building such an understanding will offer deep insights into the neural mechanisms of cognition, how and when it dysfunctions, and allow us to interpret modern AI systems that have an increasing impact on humanity.
Deciphering the mechanisms underlying mitotic nuclear envelope remodelling in the fission yeast Schizosaccharomyces japonicus (NERemodelJaponicus)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-07-01
End date: 2028-06-30
Duration (months): 24.0
Total project cost (EUR): 260347.92
EU funding (EUR): 260347.92
Participants: 2
Project status: SIGNED

Mitosis ensures faithful inheritance of genetic material in proliferating eukaryotic cells. Cellular genome is compartmentalized inside the nucleus, which is delimited by the double-membrane nuclear envelope (NE). The NE must be restructured during mitosis to allow chromosome segregation by the mitotic spindle and formation of the daughter nuclei. Eukaryotes perform this task using diverse approaches, ranging from fully “open” to fully “closed” mitosis depending on whether and when the NE breaks down. The fission yeast Schizosaccharomyces japonicus breaks the NE in anaphase, unlike its well-known relative S. pombe that undergoes closed mitosis. S. japonicus has already become an excellent discovery model providing critical insights into the rules underlying NE expansion and rearrangements of NE-chromatin contacts. Yet, we know little about the mitotic signalling and the effector mechanisms driving NE breakdown and reformation in this organism. Importantly, S. japonicus is uniquely suited for understanding mitotic nuclear membrane remodelling, as its mitosis does not involve the elaborate NE dynamics of higher eukaryotes, including disassembly and reassembly of nuclear pore complexes. I will combine cell biology, protein biochemistry, genetics, and next-generation sequencing approaches to understand: (1) how the evolutionarily conserved inner nuclear membrane protein Lem2 controls mitotic NE remodelling; (2) what are the molecular mechanisms of mitotic NE remodelling downstream of the important mitotic kinase Aurora B; and (3) what other novel factors drive NE breakdown and reformation in mitosis. Defects in NE remodelling result in spindle malfunction, aneuploidy and chromosome rearrangements that may compromise normal development and promote tumorigenesis. My work will provide a stripped-down view of membrane remodelling underlying NE breakdown and reformation in S. japonicus, with insights likely to be relevant to the open mitosis of metazoans, including humans.

Keywords: nuclear envelope remodeling,nuclear membrane,mitosis,evolutionary cell biology,fission yeast
Goldmarie Finanzen -- Sustainable Stock Portfolios with modern risk-return optimization (Goldmarie)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Germany
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-08-01
End date: 2024-01-31
Duration (months): 6.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Goldmarie Finanzen GmbH is a women led green fintech which aims to offer sustainable investments to private people. Our future customers can invest online via our web platform. All companies in our stock portfolio satisfy strict ecological and social criteria and diversified based on modern mathematical methods. Here, the individual investment goal and risk tolerance, as well as personal preferences in the realm of ecological and social goals are taken into account. The two founders and CEOs are highly qualified IT specialists with expert knowledge in mathematics and computer science. With Goldmarie Finanzen, they develop deep tech solutions to a two-fold problem: On the one hand, financial resources are needed for the green transformation. On the other hand, people would like to control the impact of their investment. In a long tail business model, Goldmarie Finanzen wants to make personalized stock instments, which were formerly available only for major investors, available to a broad public. We utilize cutting-edge technologies from mathematical optimization and financial mathematics to build the individualized investment portfolios. This includes automatic decision making and data science with profound, mathematical quality controls. The decision machinery is implemented based on modern software technologies and a custom data base, that structures and connects relevant data from different sources. With the Women TechEU Grant, we could enhance the portfolio decisions by including our customers' opinions and knowledge about investment options. An additional team member, who is specialized in mathematical optimization and an experienced software developer, would help to implement data flows and backtest tailored strategies during 6 months. We could additionally fund marketing activities related to customer information and collecting the needed data. Mentoring and networking, in particular with investors, will grow the company and ensure future funding.

Keywords: sustainable finance
Temporally complex odour information encoding (TempCOdE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-08-01
End date: 2028-07-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

A fundamental challenge for the brain is to extract relevant information from an ever changing external world. Natural odours are in a constant state of flux. Turbulent airflow shapes odours into spatiotemporally complex plumes that carry information about the olfactory scenery and provide vital clues about the location of, for example, food sources or predators. How the mammalian olfactory system extracts information about space from temporal odour dynamics, however, is still not well understood. Recent methodological advances in presenting dynamic odour stimuli, neural activity recordings and machine-vision algorithms now offer the exciting opportunity to address this fundamental question. Using a multidisciplinary approach, this project will uncover how temporally complex odour information is processed across the olfactory system and how odour dynamics give rise to behaviour. We will first investigate how temporally complex odour information is represented across key structures of the mammalian olfactory system using in vivo physiology. This will provide important groundwork for the next step, elucidating the cellular and circuit mechanisms underlying the encoding of dynamic odours in the early olfactory system. Finally, we will study which features of temporally complex odours are used for navigation behaviour by simultaneously recording and correlating the animal’s respiration sampling strategy, the dynamic odour profile encountered by the animal and neural activity from early and higher order olfactory areas in freely moving mice. By combining cellular and systems neuroscience with behavioural investigations, we aim to directly assess how mammals use olfaction to extract information about space from time. I strongly believe that this innovative research programme will generate novel and highly generalizable insights into how naturalistic sensory information is processed and that it will uncover neural mechanisms that give rise to our perception of the world.

Keywords: olfaction,sensory processing,temporally complex odours,olfactory guided navigation,plumes
Mode-selective ab-initio photoinduced dynamics in conjugated polymers (MOSAIC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: France,Germany
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-07-01
End date: 2026-06-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 4
Project status: TERMINATED

Organic conjugated materials (OCMs) possess unique electronic properties compared with other traditional semiconductor materials, due to the delocalization and high polarizability of π-electrons supporting the motion of charge carriers, as well as their significant electronic correlation and electron-phonon couplings. They present a remarkable flexibility allowing to tune their optical, electronic and mechanical properties at will through molecular engineering, making OCMs most suitable for a broad range of technical applications ranging from optoelectronics, as components of light-emitting diodes, to photovoltaic cells. Rigidity and conjugation, as well as the interchromophoric geometry, play a crucial role in the primary energy transfer mechanisms along aconjugated polymer (i.e., through-bond or through-space processes). The strong coupling between the electronic and nuclear degrees of freedom leads to self-trapping and spatial localization of excitons, in a region whose spatial length is determined by conformational defects. Manipulating these nuclear degrees of freedom may lead to a blockade or an enhancement of energy transfer along the bond. Recent experiments have pointed out that in specific polymers exciton transfer is a coherent process rather than a sequence of incoherent hopping type events. The accurate description of these photoinduced pathways considering all degrees of freedom involved constitutes a challenge to date. The goal of the fellowship is to advance state-of-the-art computational methods for describing the photoinduced and laser-driven, coupled electron-nuclear dynamics of large conjugated molecules, with the aim to include quantum coherence effects and to enable predictive calculations of exciton dynamics and of energy transfer in such polymeric systems. The researcher will carry out the fellowship in the Laboratory of Collisions, Aggregates and Reactivity, University of Toulouse III, under the supervision of Dr. Nadine Halberstadt.

Keywords: surface hopping,quantum trajectories,organic conjugated materials,exciton dynamics,local control theory,mixed quantum classical methods
New remote non-invasive monitoring solutions for ensuring the health of mothers and babies before and after birth (Newlife)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: Netherlands,Germany,Switzerland,Ireland,Finland,Sweden
Call: HORIZON-KDT-JU-2021-1-IA (HORIZON-KDT-JU-2021-1-IA, 2021)
Start date: 2023-01-01
End date: 2026-06-30
Duration (months): 42.0
Total project cost (EUR): 21903005.94
EU funding (EUR): 6162183.02
Participants: 31
Project status: SIGNED

There is increasing focus on the well being of mothers and babies, both before and after delivery and early detection of pathologies to prevent mother and perinatal morbidity and mortality. The overall well being of mothers also has longer term impact: women who remain healthy during pregnancy and after birth are more likely to stay healthy later in life and have better birth outcomes, also influencing the infancy, childhood and adulthood of their children. NewLife project will develop new remote non-invasive monitoring solutions for ensuring the health of mothers and babies before and after birth. The target is to develop emerging non-invasive methods for gathering vital data and analysing it with advanced AI/ML methods, to be able to secure life in its most vulnerable phase. For clinical acceptance, the developed solutions need to be well integrated to the clinical workflows, with proper data integration, security, safety, and medical qualification. The technologies and solutions developed are demonstrated in five use cases for both hospitals and personalized monitoring in home environments: 1) Pregnancy & parent companion, 2) Smart garment for monitoring of pregnancies & complications, 3) Fetal monitoring patch for high-risk pregnancies, 4) Newborn monitoring with smart clothes, and 5) Newborn monitoring -well being in bed. With the developed solutions, NewLife project will contribute to the disruption of the health care models: by focusing on preventive actions rather than treating diseases, and moving healthcare from hospitals to home.

Keywords: ehealth,remote healthcare,medical sensors,ultra sound monitoring,smart textile,artificial intelligence,pregnancy monitoring,risk birth,premature birth,medical data acquisition and data sharing
Investigating Caspase 4 and Toll-like Receptor 4 Modulation by Endogenous Cardiolipin in Health and Barth Syndrome (CL-ImmunoDimmer)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-22
End date: 2027-09-21
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 1
Project status: SIGNED

Barth Syndrome (BTHS) is a disease characterised by reduced production of unsaturated mitochondrial cardiolipin (CL) and increased production of abnormal CL with saturated chains. Chronic inflammation and increased vulnerability to infection are major contributors to mortality in BTHS patients. The connection between these immune dysfunctions and CL modifications is not understood. My research has shown that unsaturated CL inhibits caspase 4 (CASP4) and Toll-like Receptor 4 (TLR4). Moderate CASP4 and TLR4 activation by bacterial triggers is essential for antibacterial defence, while uncontrolled activation results in infection lethality and inflammatory disease. My preliminary data show that abnormal CL similar to the one found in BTHS patients does not inhibit CASP4, and saturated CL activates TLR4. These findings suggest that in health, unsaturated CL acts as a dimmer to fine-tune immune reactions, while in BTHS, this dimmer is compromised, resulting in immune dysfunction. To investigate this hypothesis, this proposal ideally combines my expertise in cardiolipin and mitochondria research with the host’s expertise in gene editing and live microscopy. Using well-established methodologies, we will deplete CL from monocytes and macrophages and study how this affects CASP4 and TLR4 activation. Moreover, I will characterise BTHS immune response through the analysis of inflammatory markers in patients’ plasma, and patients’ neutrophils, monocytes and macrophages CASP4 and TLR4 response. This will provide a deeper mechanistic understanding of inflammatory processes in both health and disease, potentially identifying CL, CASP4, and TLR4 as new targets for treating BTHS. While I will enhance the team’s multidisciplinary character and provide collaboration opportunities, I will be trained in cutting-edge techniques and get leadership and network opportunities crucial for my long-term goal of scientific independence.

Keywords: caspase 4 casp4 toll like receptor 4 tlr4 cardiolipin cl barth syndrome bths non canonical inflammasome toll like receptors tlrs
CRETE AEGEAN H2 VALLEY (CRAVE-H2)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Innovation actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: Greece,Italy,Netherlands
Call: Hydrogen Valleys (small-scale) (HORIZON-JTI-CLEANH2-2022-2, 2022)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 11049571.48
EU funding (EUR): 7888243.63
Participants: 10
Project status: SIGNED

The Cretan-Aegean Hydrogen Valley is covering a defined geographical area in which hydrogen will serve energy storage and energy aggregation activities via reuse of energy stored to the grid through fuel cells as well as Green H2 Road Transport. In the future Green Marine H2 Fuel applications, as well fuel for industry via its use in adjacent traditional power plant. The CRAVE-H2 is a substantial financial investment and covers all necessary steps in the hydrogen value chain, from production (securing dedicated renewable electricity production from the 582 MW Aegean project) to subsequent high pressure storage & distribution to hydrogen filling station and potential other off-takers. The Cretan-Aegean hydrogen valleys has started and has the full support of the regional authorities (partners) that pursue a "hydrogen economy”. CRAVE-H2 is necessary for piloting hydrogen market in Crete and Greece but also located in very pivotal location where leading partner EUNICE interconnects their 580 MW Aegean Wind Energy project and their new Greek - Egypt electricity transmission interconnection allowing for cheap African PV power to be introduced into the Greek electricity and hydrogen market. The location of the main hydrogen production and the above connections is the port of Atherinolakkos which could allow future deployment of use of hydrogen as maritime fuel. The main assets /scope of CRAVE - H2 are the integration of : • Alkaline Electrolyser: +3 MWel +500 tons/year H2 from DENORA • H2 compression and storage together with HRS: 1 ton • PEM Fuel Cell: 0.4 MWel from BALLARD • Employ Hydrogen buses by local company. • Re-use of water produced from the FC • Including all installation works and required AC/DC rectifier and DC/AC converters from EUNICE • LCA / LCC and study of other H2 uses in power plant, industry and maritime applications.

Keywords: hydrogen,system,transportation,energy storage,fuel cell,electrolyser