Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Rugged Long-lasting Vertical-Axis Wind Turbine for Extreme Wind Conditions (NJORD)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Iceland
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-11-01
End date: 2017-02-28
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Extreme weather conditions (i.e. strong and unsteady winds, icing, etc.) - that countries such as Iceland and the other four Nordics (Sweden, Denmark, Norway, and Finland), the UK, Ireland, Canada´s Prairies, Northern US, Russia, and Nigeria along with high altitude sites face - make traditional wind turbines (horizontal-axis) to spin out of control resulting in catastrophic system failure in the first year of operation. As a result, these locations needed a different kind of wind technology capable of working over a wide production range (whether it’s in the stormy afternoon, in hurricanes or on calm and icy winter nights in the range of -10 to -30 °C) with virtually no need of maintenance. Thus, IceWind has created a rugged, standalone, and cost-effective vertical-axis wind turbine (VAWT) of unique and fabulous blade design, great durability and nearly maintenance-free for off-grid applications that require a continuous (no cut-outs) source of power (electricity and heating). The excellent match of aerodynamics and materials give our NJORD turbines unique features such as optimal structural stability, strength, and hence durability to withstand the most extreme wind conditions. Our VAWT can produce electricity at very low wind speeds as well as for high speed of strong winds spinning elegantly, non-stop, and noiseless. As for our commercial strategy, we plan to respond: 1) directly to individual end-users of isolated areas for residential applications (i.e. cabins, homes, and small farms) mainly in Iceland and other EU countries (i.e. the other four Nordics, the UK, Ireland, etc.), 2) telecommunication operators for telecom towers worldwide, and 3) developing countries such as Nigeria, all demanding a reliable and sustainable source of power generation. Expected profit after deducting costs of purchase, manufacture and distribution fees amounts to a cumulative 20M€ turnover market opportunity for the 2020-2024 period.

Keywords: wind energy,vertical axis wind turbines,small wind,savonious,renewable energy,nordic countries,extreme wind conditions,hurricanes,icing,isolated areas,cabins,telecom towers
De Novo Fatty Acid Synthesis from Alkane Feedstocks and CO2 (FAT-FEEDOX)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: CLOSED

FAT-FEEDOX deals with the development of an innovative and unconventional catalytic de novo approach to fatty acids, privileged motifs on the manufacture of detergents, soaps, dyes, plastics, agrochemicals and pharmaceuticals, using simple, available and abundant carbon dioxide (CO2) and alkanes, compounds derived from the crude oil. Specifically, FAT-FEEDOX will promote a synergistic catalytic C(sp3)–H activation /CO2 insertion event of readily available alkane chemical feedstocks. The project will offer all the necessary understanding behind the factors influencing both C(sp3)–H activation and the subsequent CO2 insertion event, thus opening up new horizons in preparative organic chemistry as well as offering solutions to a social, industrial and academic problem such as the use of multiple chemical feedstocks to produce added-value compounds. FAT-FEEDOX will lead to new knowledge in synthetic design, thus providing new logics in retrosynthetic analysis that will likely attract the interest of both pharmaceutical and industrial laboratories and a significant step-forward for our circular economy. This project sits at the interface between the applicant and the supervisor’s background. The applicant has the experience in C-H functionalization part, which is defined as the first step of this project. The applicant will gain more skills in the CO2 activation from the host group during this fellowship. Therefore, the applicant can contribute his own expertise in part of this project independently, meanwhile he can learn new techniques from the host, which will benefit back. The fellowship will develop the applicant’s capacities by providing new laboratory skills, which will broaden his research field. This invaluable experience will make him more independent and competent for building his future research career.

Keywords: fatty acids,alkanes,c h activation,carbon dioxide,borylation
Development of a new process analytical technology based on an innovative nanoplasmonic detection array for monitoring glycosylation of monoclonal antibodies (PATGlycoPrint)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 203852.16
EU funding (EUR): 203852.16
Participants: 1
Project status: CLOSED

Glycosylation of therapeutic antibodies is one of the most critical quality attributes (CQAs) in biopharmaceutical manufacturing because of its strong impact to the treatment efficacy. Many parameters in the production process including upstream cell culture and downstream purification can significantly change the antibody glycosylation profiles. Therefore, monitoring and quality controlling of glycosylation is central to ensure high quality and consistent products. Unfortunately, this requires advanced analytical equipment and procedures that are expensive and time consuming and not suitable for on-line applications. Process analytical technologies that enable real-time monitoring of glycosylation during the production process would thus be a game changer in the biopharma industry. The aim of this research action is to develop and evaluate a new process analytical technology based on an innovative nanoplasmonic glycan-binding array that can detect the glycosylation patterns of downstream and upstream samples immediately or in a few minutes, respectively. The proposal is established to support the experienced researcher (ER), who wish to resume research in Sweden after a career break, and to enhance the ER´s employment opportunities in both academic and industrial sectors by an extensive two-way exchange of knowledge between the host and the ER as well as innovation and networking opportunities. The research project includes different branches of knowledge including biosensors, nanomaterials, biomanufacturing, analytical chemistry as well as surface, organic and peptide chemistry. In line with the MSCA-2018 Work Programme, this broad interdisciplinary training is expected to diversify the ER competence and greatly impact the ER’s future career while developing and exploring new technologies that can dramatically improve current strategies for bioproduction.

Keywords: nanoplasmonics,glycosylation,process analytical technology,antibodies,oboc,combinatorial libraries
Brains that fire together wire together: Interbrain plasticity underlies interaction-based learning (INTERPLASTIC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Israel
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2021-10-01
End date: 2026-09-30
Duration (months): 60.0
Total project cost (EUR): 2597700.0
EU funding (EUR): 2597700.0
Participants: 1
Project status: SIGNED

Traditionally, brain plasticity was viewed as a change occurring in synapses, brain structures and functional networks, within an individual brain. Considering that social interactions play a major role in the acquisitions of skills and knowledge, I suggest a new approach for understanding interaction-based learning that focuses on inter-brain plasticity. The term coined here, inter-brain plasticity, will be defined as the short and long-term experience-dependent changes in brain-to-brain coupling. I argue that inter-brain plasticity in the observation-execution system develops over the course of interaction-based learning to facilitate information exchange between partners and thus learning. The proposed study aims at introducing a new theory on how inter-brain networks reorganize following training in interaction-based learning. It has three objectives: 1) To develop a model of inter-brain plasticity during learning (short-term), following training (long-term) and generalization between/within interaction partners; 2) To develop a novel dyadic-neurofeedback technology that allows drawing causal inferences between inter-brain plasticity and learning; 3) To test whether diminished inter-brain plasticity in Autism Spectrum Disorders may be reversed following training with the new dyadic neurofeedback. To address these questions, I will take advantage of the high temporal resolution of state-of-the-art dual-functional Near-Infrared Spectroscopy (fNIRS) setup and examine how intra- and inter-brain networks reconfigure during learning of various skills, ranging from motor learning to language acquisition. The proposed experiments will lay the foundation for a new field of research focusing on the dynamics of inter-brain networks. The inter-brain plasticity approach will radically change how we view neuroplasticity. It will allow for the first time probing the long-term changes in the reconfiguration of inter-brain networks.

Keywords: social learning,brain to brain coupling,plasticity,fnirs,neurofeedback,hyperscanning
European Research Infrastructure on Highly Pathogenic Agents 2 (ERINHA2)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Coordination and support actions
Countries involved: Austria,Germany,Germany,Germany,Germany,Spain,Italy,Belgium,Hungary,Greece,Romania,Sweden,France,United Kingdom,Portugal
Call: Preparatory Phase of ESFRI projects (H2020-INFRADEV-1-2015-2, 2015)
Start date: 2016-01-01
End date: 2017-06-30
Duration (months): 18.0
Total project cost (EUR): 1443927.0
EU funding (EUR): 1443927.0
Participants: 17
Project status: CLOSED

ERINHA2 aims to complete the work carried out during the first preparatory phase (PP1) - ERINHA - in order to reach the financial, administrative and technical maturity necessary to complete the establishment of the Research Infrastructre and ensure that the operation phase can begin in 2018. ERINHA2 will therefore finalise the decision to use the status of an association and prepare the necessary legal document to register the RI depending on the country voted on to host the Central Coordinating Unit. ERINHA2 will prepare all procedures and protocols (human resources, IPR, ethics) needed to effectively operate the RI. The financial and business plans prepared in ERINHA (PP1) will updated and presented to national and international stakeholders to obtain their agreement to fund the infrastructure. An overarching group of activities - WP5, Stakeholders and commitment - will aim to accompany all partner countries in their efforts to obtain agreements and funding. This WP5 will ensure all relevant stakeholders and potential users are informed of the progress, services and benefits of ERINHA. The utlimate outcome of ERINHA2 will be the signtature of the ERINHA statutes among the founding countries to officially establish the RI and enter into the construction phase.

Keywords: maturity,financial commitment,agreement,research agenda,legal framework,operational procedure,funding,advocacy,potential user base
Precise and smart nanoengineered surfaces: Impact resistance, icephobicity and dropwise condensation (NICEDROPS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-03-01
End date: 2023-02-28
Duration (months): 72.0
Total project cost (EUR): 1908624.0
EU funding (EUR): 1908624.0
Participants: 1
Project status: SIGNED

Water freezing (icing) and condensation are ubiquitous in our life. Preventing undesirable icing on surfaces with minimal energy and chemical use, and improving the efficiency of condensation heat exchangers has broad societal value. Thus, I aim to use fundamental insights to offer energy-efficient solutions for undesirable ice formation and promoting dropwise condensation using novel and robust nanoengineered surfaces. My objectives are: i) to realise thermodynamically guided metallic surfaces with precise (<10 nm) morphology and controlled superficial stiffness for energy-efficient icing prevention and sustaining dropwise flow condensation ii) to rationally intercalate polymers and/or suspensions into surface nanotextures and exploit nanomechanics in order to enable robust and smart nanoengineered surfaces for high speed impact, abrasion and chemical resistance; stable icephobicity (delaying freezing); and sustained dropwise condensation. iii) to develop new fundamental insights to: a) prevent icing due to high speed (~100 m/s) supercooled droplet/ice crystal impact; b) realise icephobicity down to -30 degrees Celsius; c) minimise ice-surface adhesion; and d) sustain dropwise condensation at high (50-100 m/s) vapour speeds. The proposal emphasis on energy efficiency is aligned with the EU's 20/20/20 Strategic Energy Technology (SET) Plan. To exemplify their salient impact, the proposed smart nanoengineered surfaces offer a passive solution for airplane icing (and related accidents) and will delay evaporator icing on air source heat pumps and refrigerators, thereby helping to lower the energy use in buildings and cold storages. The latter are tied to the global food storage and distribution challenges. Similarly, sustained dropwise condensation will make condensers in process industry and steam power plants compact and efficient. Optimally, only ~1 micron of the surface depth will require treatment – this will minimize chemical use and promote sustainability.

Keywords: icephobic surfaces,flow condensation,nanoengineered surfaces
Funds to make MSCA-IF project accessible for a post-doc with Systemic Lupus Erythematosus, Autoimmune Neutropenia and Attention Deficit Disorder. (CoL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Action type: Marie Skłodowska-Curie actions
Countries involved: United Kingdom
Call: MSCA Special Needs Allowance (H2020-IBA-MSCA-SNLS-2020, 2020)
Start date: 2021-04-16
End date: 2025-08-15
Duration (months): 52.0
Total project cost (EUR): 56372.0
EU funding (EUR): 56372.0
Participants: 1
Project status: SIGNED

Request of financial support to cover the additional costs that researchers/staff members with disabilities face due to the increased costs of their mobility and/or to ensure necessary assistance by third persons or for adapting their work environment.

Keywords: systemic lupus erythematosus,autoimmune neutropenia,attention deficit disorder,administration assistance,disability,assistive equipment,accessibility,travel assistance
The role of microbial Oxylipins in the MIcrobe-hosT dialogue (OMIT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Ireland
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-11-01
End date: 2023-10-31
Duration (months): 24.0
Total project cost (EUR): 196590.72
EU funding (EUR): 196590.72
Participants: 1
Project status: SIGNED

OMIT aims to examine the role of microbial Oxylipins in the MIcrobiome:hosT dialogue. Oxylipins liberated from the oxidation of fatty acids are appreciated as key chemical signals perceived by both microbe and man. Human oxylipins (hOXY), comprising eicosanoids, docosanoids and octadecanoids are well characterised; they are implicit in many biochemical and signalling pathways in humans, including cell migration, proliferation, chemotaxis, immune reactions and most importantly, they are key regulators of inflammation. However, the diversity, functions, impact and mechanistic roles of microbially derived oxylipins (mOXY) are not well understood. State-of-the-art ultra-performance liquid chromatography-mass spectrometry (MS) platforms (secondment at Waters MS Headquarters, UK) will be developed and validated for oxylipin analysis in faecal samples and bacterial supernatants derived from co-incubation experiments (i.e. bacteria and oxlipin precursor). The latter will facilitate the discovery of novel mOXY. Additional bacterial biofilm assays will be performed to examine the role of mOXY in microbe-microbe interactions. To determine the contribution of mOXY in health and disease, biobanked samples from healthy volunteers and Crohns disease patients will be analysed. In vitro cell culture experiments and gene expression profiling will determine the function of mOXY in microbe-host interactions. During this project, the applicant will receive high quality training through research that will significantly improve scientific knowledge and provide a strong platform for building an independent research career. In line with the Work Programme for the MSCA fellowships, the knowledge and competencies gained by the applicant will add to developing her potential to achieve professional maturity and leadership in the field so that she may continue to make significant contributions to society and the economy.

Keywords: oxylipins,microbiome,host,pufa,lipid mediators,mass spectrometry,commensal bacteria
An Innovative and Energy-Efficient Radio Frequency Pretreatment on Emerging Micropollutants and Transformation Products in Anaerobic Sludge Digestion for Waste Reuse (RADIOFREPOLIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Türkiye,Canada
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-08-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 242709.12
EU funding (EUR): 242709.12
Participants: 2
Project status: SIGNED

Sludge management in wastewater treatment plants is still one of the most pressing issues due to dramatic increases in sludge production, disposal costs and increasing stringent regulatory restraints. As the most sustainable and cheapest disposal option, agricultural use of biosolids is encouraged as a part of a resource recovery solution by turning waste into a key resource. Anaerobic digestion is a common practice for sludge stabilization as an energy-efficient process before the beneficial reuse of biosolids. However, presence of the emerging micropollutants such as pharmaceutical and personal care products is creating potential human and environmental health threats despite the technological advancements in anaerobic sludge digestion. Europe needs to take immediate action for solving this issue; to safeguard the Union's citizens from environment-related pressures and risks to health and wellbeing within objectives of the EU 7th Environment Action Programme. RADIOFREPOLIS intends to investigate the occurrence and transformation of target pharmaceutical and personal care products by applying an innovative and energy-efficient radio frequency sludge pretreatment followed by anaerobic digestion as the first time in the literature for moving towards non-toxic environment. Proposed solution will reduce the uncontrolled release of micropollutants into the environment via sludge as well as reducing the quantity of excess sludge, improving the quality of sludge and increasing renewable energy to obtain a positive energy balance of the overall process, which will contribute to competitiveness of Europe. RADIOFREPOLIS will transfer knowledge on this newly acquired custom-built radio frequency heating technology to Europe and develop a novel project with multidisciplinary collaboration. Furthermore, this fellowship will increase knowledge and experience of the highly qualified researcher in area of environmental biotechnology where Europe needs highly trained researchers.

Keywords: sludge,anaerobic digestion,emerging micropollutants,waste minimization,resource recovery,energy,electromagnetic pretreatment,radio frequency,microwave,pharmaceuticals,personal care products