Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Imagination and Religious Credence (IRC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Belgium
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-06-01
End date: 2016-07-31
Duration (months): 14.0
Total project cost (EUR): 93800.0
EU funding (EUR): 93800.0
Participants: 1
Project status: CLOSED

Many philosophers and cognitive scientists have a habit of using the word “belief” as though it refers to a single, simple sort of cognitive attitude. But if we take empirical evidence from cognitive science of religion seriously, we will see that this habit is a source of confusion. Just as it is a mistake in astronomy to assume that Venus and the North Star are the same kind of entity because they are both “stars,” so too it is a mistake in theorizing the nature of belief to treat what I call religious credence and what I call factual belief as the same type of attitude. I have already argued in my paper “Religious Credence is not Factual Belief” (forthcoming, Cognition) that our best psychological theory of cognitive attitudes, in conjunction with psychological and anthropological evidence, will treat these two attitudes differently. The research aim of the project proposed here is to elaborate on my theoretical apparatus to produce a book-length monograph that will serve philosophers and cognitive scientists interested in religious “belief," and the corresponding aim for public dissemination is to make this research popularly available through essays, blogs, radio, and public debate. I propose to write _Imagination and Religious Credence_ while in residence at the Centre for Philosophical Psychology at the University of Antwerp. This will be an important step in my career development. My career aim is to achieve a level of distinction in research that will justify (1) mentoring PhD and postdoctoral researchers and (2) directing a research group similar in structure to the Centre for Philosophical Psychology. Advancing my own research and being embedded in the Centre, which has a stellar history of developing research careers, will both be critical steps toward realizing these career goals.

Keywords: belief,imagination,religious credence,cognition,action,ritual,sacrifice,pretense,play
Birthing Abolition: Reproduction and the Gradual End of Slavery in Brazil (BIRTHBRAZIL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-09-01
End date: 2019-08-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

BIRTHBRAZIL is an interdisciplinary project that will analyze how enslaved women’s reproductive trends and practices shaped the gradual abolition of slavery in the middle to large plantation holdings of Rio de Janeiro, Brazil from 1850 (the definitive end of the country’s slave trade) to final abolition in 1888. The project aims to contend that the struggle to end slavery was intimately entangled not only with elite understandings of slave reproduction but also with enslaved women’s own agency. To do so, it examines demographic trends among the enslaved population, elite views of enslaved women’s reproduction, and enslaved women’s own reproductive practices and agency. Like most Atlantic slave societies, the Brazilian slave population was reproduced through imports and not natural growth. Historians have argued that for 19th-century Rio de Janeiro state, harsh labour regimes and disease caused negative growth rates, dismissing the idea of “reproductive resistance”—the female enslaved practices of abortion and infanticide as purposeful attacks on the institution of slavery—popular in theories on Caribbean and US slavery. While enslaved women’s fertility control may not have caused negative population growth in 19th-century Rio de Janeiro state, BIRTHBRAZIL hypothesizes that enslaved women’s practices of fertility control played an important symbolic role in how elites understood and approached slavery itself. The findings of BIRTHBRAZIL are expected to demonstrate that enslaved women’s fertility control, both real and imagined, created the opportunity for abolitionists to implement the legal framework that abolished slavery. In doing so, the project provides historical background to current-day debates on reproductive rights, women’s health, and gender equality. The results will be disseminated through an academic monograph, peer-reviewed open-access publications, a website, an international conference, public history blogs, and a series of community lectures.

Keywords: abolition of slavery,atlantic world,brazil,reproduction,women and gender,history of medicine,enslaved agency,fertility control
PIK3CA inhibition in patients with the CLOVES syndrome (CureTheCloves)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-02-01
End date: 2018-07-31
Duration (months): 18.0
Total project cost (EUR): 148750.0
EU funding (EUR): 148750.0
Participants: 1
Project status: CLOSED

The Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi, Scoliosis/Skeletal and Spinal (CLOVES) syndrome is a genetic disorder due to a gain of function mutation of the PIK3CA in a mosaic fashion. This rare condition is associated with severe deformation and poor survival. We identified a new drug able to dramatically improve the outcome of patients with this rare disease. The purpose of the Proof of Concept grant is to better understand the molecular effect of this drug and to rapidly accede to Orphan drug designation.

Keywords: pik3ca,podocyte,kidney dysfunction,tumors,venous dilation
Better vision after cataract and refractive surgery with photonics technology (BeVision)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Active ageing and self-management of health
Action type: SME instrument
Countries involved: Spain
Call: Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2017-11-01
End date: 2020-04-30
Duration (months): 30.0
Total project cost (EUR): 2486788.25
EU funding (EUR): 1740751.77
Participants: 1
Project status: CLOSED

As we get older, we all will develop eyesight problems. Around the age of 65 more than half of us suffer from eye lens clouding, or cataracts. Cataract surgery is now the most common operation in Europe, with 4.3 million people getting treated each year, a figure that will only increase due to our fast aging population. However, 200,000 of them are not satisfied with the outcome of their eye correcting surgeries as they can’t experience on forehand what their vision will be. Voptica has developed the Visual Adaptive Optics (VAO) simulator, a disruptive innovation in eye testing, allowing patients to experience the effect of intraocular lenses or laser surgery on their vision before the actual operation, helping the patient and doctor to select their best solution and understand what their vision will be like post-surgery. Our technology is used by world-leading research institutes and lens-manufactures, but to prepare VAO for clinical market introduction our project BeVision will refine its software protocols, make it interoperable and clinically validate the technology. After a successful clinical validation, VAO will be the only medical device in the world that can measure objectively all eye aberrations of patients and, subsequently, simulate the different optical solutions to correct the patient’s eye imperfections during visual testing. Our technology will dramatically improve the outcomes of cataract and laser refractive surgeries. Our highly competitive technology can swiftly disrupt the $4.4 billion ophthalmology device market, generating a rapid business growth for Voptica, with a cumulative revenue of € 36.4m and a profit of € 8.6m by 2025. To make BeVision a commercial success, we have assembled a consortium with a solid track record in the development, optimisation, clinical validation and commercialisation of ophthalmic devices and have all the skills and resources for its commercial exploitation to benefit our business and Europe.

Keywords: simulation,iols,laser surgery,opthalmologist,vision
PROcessing Diluted Aqueous Systems (PRODIAS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Sustainable, resource-efficient and low-carbon technologies in energy-intensive process industries
Action type: Innovation actions
Countries involved: Germany,Germany,Germany,Germany,Belgium,Finland,Sweden,France,Netherlands,Netherlands,United Kingdom
Call: Improved downstream processing of mixtures in process industries (H2020-SPIRE-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 13627823.25
EU funding (EUR): 9993008.4
Participants: 11
Project status: CLOSED

The use of renewable resources in the process industries is socially desirable and a market pull for products has started to develop in recent years, but renewable products have to compete with identical or similar-in-application products based on fossil raw materials in terms of quality and production cost. One of the main reasons for currently higher production costs of products based on renewable resources is that the production routes involve processing complex dilute aqueous solutions from which the desired products have to be separated during downstream processing. Consequently, a major challenge the process industry is facing, is the development of cost- and energy-efficient water removal and product-recovery techniques. Today downstream processes for products based on renewable resources are often developed using methods from the petrochemical area being insufficiently adapted to the new applications. A re-thinking of downstream process development and the development of suitable methodologies for a fast-track development of tailored downstream processes as well as the optimisation of separation technologies are urgently needed in order to unlock the potential of the renewable-based product market for the European process industry. PRODIAS addresses this challenge by developing and implementing: - a toolbox of highly innovative, cost-effective and renewable-tailored separation technologies; single technologies and/or hybrid systems - novel, optimized apparatus and machinery to enable for and host the developed technologies - in combination with an integrated design approach for the fast-track selection of appropriate technologies. The main advantages of the PRODIAS toolbox and integrated design approach for processes based on renewable resources are - significantly decreased production cost - increased productivity and efficiency - faster process development and commercialization - significantly lower energy consumption leading to less CO2 emmissions.

Keywords: water removal,product recovery,renewable based products,processing of complex dilute aqueous solutions,selective separation,low energy concentration
Alpha1H: A Unique Bladder Cancer Therapeutic, Acting with Great Precision (HAMLET-BC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2020-06-01
End date: 2022-11-30
Duration (months): 30.0
Total project cost (EUR): 3138778.0
EU funding (EUR): 2197144.59
Participants: 2
Project status: CLOSED

Novel cancer treatments should ideally combine efficacy with selectivity. Tissue toxicity and side-effects are still the norm, however. Although new targeted therapies act with greater precision, the notion of tumour-specific cell death is justly regarded with scepticism. The Swedish company Hamlet Pharma provides new cancer treatments based on a peptide-based molecular approach for targeting and killing tumour cells with greater precision. Its proprietary drug complex, HAMLET (‘Human Alpha-lactalbumin Made LEthal to Tumour cells’) is derived from the human breast milk protein, alpha-lactalbumin, and represents a ground-breaking therapeutic solution with high tumour-killing capacity, high target specificity, killing >40 different types of tumour cells and no demonstrated toxicity. As such, it has the potential to revolutionize cancer treatment. Hamlet Pharma is now advancing HAMLET and the synthetic drug candidate Alpha1H along the clinical development pipeline as anti-cancer therapeutic for early stage bladder cancer. The company is focusing on bladder cancer given the high clinical need for more effective and safe treatment options. Bladder cancer has the highest recurrence rates (70%) and treatment costs per patient among all cancer types (total costs in Europe: >€4.9 billion). Recent successful outcomes include initial Phase I/II clinical trial data, proving that Alpha1H acts with high efficacy without any detectable toxicity. With the EIC Accelerator funding, Hamlet Pharma will finalise Phase I/II clinical safety and efficacy studies and advance development of Alpha1H towards a Phase III trial (i.e. ready for licensing deal or IPO). Conversations with potential licensing partners and investors are ongoing. Alpha1H will be an important showcase of the impact HAMLET will have on cancer treatment (expected cumulative revenues: €350M five years after market approval). Generated revenues will be reinvested into development of HAMLET for other cancer indications.

Keywords: bladder cancer,non muscle invasive bladder cancer,tumour,oncology,anti cancer,therapeutic,drug development,lactalbumin,human breast milk,protein lipid complex,biological,prophylactic
Knowledge Inventory for hydrogeology research (KINDRA)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Enabling the transition towards a green economy and society through eco-innovation
Action type: Coordination and support actions
Countries involved: Ukraine,Germany,Ireland,Spain,Spain,Italy,Spain,Switzerland,Serbia,Belgium,Finland,Greece,Croatia,Hungary,Poland,Slovenia,Russian Federation,Hungary,Sweden,France,Czechia,Netherlands,Denmark,United Kingdom,Portugal
Call: Dissemination and exploitation, ICT, knowledge, gaps, research needs, etc (H2020-WATER-2014-one-stage, 2014)
Start date: 2015-01-01
End date: 2018-03-31
Duration (months): 39.0
Total project cost (EUR): 1119338.0
EU funding (EUR): 1108669.31
Participants: 28
Project status: CLOSED

Practical and scientific knowledge related to hydrogeology research and innovation are scattered amongst various actors in Europe. The overall objective of KINDRA is to create an inventory of this knowledge-base and then use the inventory to identify critical research challenges in line with the implementation of the WFD and new innovation areas within integrated water resources management based on the latest research. Project objectives: 1. Create a uniform EU-harmonised categorisation approach / terminology for reporting groundwater research (a Hydrogeological Research Classification System – HRC-SYS). Since such uniform classification does not exist at the moment, ongoing research activities, national/European hydrogeological research activities, agendas and strategies are difficult to report and even more difficult to compare. 2. Carry out EU-wide assessment of existing practical and scientific knowledge (using the developed HRC-SYS) focusing on EU, national, regional, international and EU-third party scientific activities. This assessment will be implemented with the help of the national members of EFG. 3. Create a European Inventory of Groundwater Research and Innovation (EIGR). This register will be supported by a web-service that will be searchable by selected key-words and will support users with query functions for statistics, diagrams, and others concise data elaboration. 4. Use the data in the register and the developed analytical tools (qualitative/quantitative) to assess the performance of key ongoing EU, national, regional, international and EU-third party hydrogeological scientific and innovation activities and results. 5. Compare the results with existing recommendations and position papers on groundwater related research requirements. 6. Define research gaps and corresponding suggestions for research agendas in line with WFD, and WssTP recommendations.

Keywords: hydrogeology,groundwater
Land Degradation Neutrality: Towards an Earth Observation-based Early Warning System for Savannah Degradation (SAV-EO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2022-01-01
End date: 2024-04-30
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

Savannahs are important ecosystems that are found on almost half of the African continent. Unfortunately, they undergo massive conversions and are affected by land degradation processes leading to a decline in the ecosystem services they provide to some of the continent’s poorest and most vulnerable human populations. Reductions in the productivity of dryland savannahs have major social and political implications, and the United Nations (UN) has labelled the accurate quantification of savannah degradation as of high priority. Monitoring the woody component of savannah land cover is, therefore, needed to enhance the understanding of broad-scale changes in savannahs & their relationship with ecosystem degradation. Over large scales, this can only be achieved in a cost-effective manner using Earth Observation (EO) technologies. The development of SAV-EO is, therefore, proposed which will employ novel remote sensing methodologies, based on thousands of freely-available optical & radar satellite data for the mapping & monitoring of fractional woody cover over the entire southern African savannah region (1,500,000km2). A monitoring tool that identifies underlying land degradation processes, such as bush encroachment & deforestation, will also be devised based on a dense time-series analysis approach using all available data from the 45-year long Landsat archive. Another objective of SAV-EO is to provide an advancement in the design of operational indicators for the assessment & monitoring of land degradation, within the Land Degradation Neutrality framework suggested by the UN, in order to achieve the target of the Sustainable Development Goals to combat desertification by the 2030. The innovative algorithms, data & outputs will be made available open-access via a bespoke web-GIS platform & numerous dissemination & communication activities, thus providing an invaluable resource for scientists & policy makers alike.

Keywords: savannah fractional woody vegetation cover,landsat,compositing,pre processing,image classification,unccd,deep learning,ccdc,land degradation neutrality,google earth,web gis,open access
Development of CDC production technologies for the next generation of supercapacitors, feasibility study (SKLCarbon)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Estonia
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2014, 2014)
Start date: 2014-10-01
End date: 2015-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Skeleton Technologies is a developer and manufacturer of high performance ultracapacitors, devices which store and deliver energy much more rapidly than conventional batteries. Their specialist technology, based on in-house-manufactured carbide derived carbon (CDC) electrodes, produces 2.5 times the power to weight ratio, subsequently a 40% reduction in costs, compared to the state of the art. The company aims to build on successful sales to niche space and motorsport markets, by up-scaling CDC production, reducing costs, allowing for more ubiquitous adoption of their products for energy-saving applications in price-sensitive markets. Initially, Skeleton will fulfil explicit demand in the automotive industry for high current, high power/weight ultracapacitors, facilitating advances in stop-start, regenerative braking and cold starting technologies. Applications have also been identified in smart grids, supporting renewable energy sources and circumventing power outages. Skeleton also plans to market its specially treated CDC materials to manufacturers of ultracapacitors and Li-ion capacitors, and to investigate further identified uses, such as in advanced batteries, gas adsorption, water desalination and as a catalyst in fuel cells. The Phase I feasibility study will comprise two consecutive parts: 1) completion of the planning for the up-scaled CDC production facility (to be implemented in the 24 month Phase II project), and 2) conduction of collaborative consultation with other ultracapacitor manufacturers, who will be early adopters of the CDC. The project will address the European and global challenge of developing low carbon and efficient energy systems. CDC based ultracapacitors will facilitate advanced energy efficiency and energy recapturing systems, and will support renewable energy production and smart grids. Fulfilment of high demand in a global market projected to see 30% annual growth, will also represent significant economic benefits for member sta

Keywords: carbide derived carbon,carbon,supercapacitors,electrode