Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Citizen-Oriented Valorisation for Advancement, Learning and Uptake in Europe (CO-VALUE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Reforming and enhancing the European R&I System
Destination: Reforming and enhancing the European R&I System
Action type: Coordination and support actions
Countries involved: Belgium,Italy,Spain
Call: Experimentation and exchange of good practices for value creation (HORIZON-WIDERA-2023-ERA-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 1046625.0
EU funding (EUR): 1046625.0
Participants: 4
Project status: SIGNED

The overall objective of CO-VALUE is to boost uptake and deployment of research results by adopting a co-valorisation approach that strengthens the role of societal actors in knowledge valorisation. Citizen engagement will be embedded in knowledge valorisation by deploying capacity building, peer learning actions and experimentation. CO-VALUE will capitalise on and contribute to EU initiatives such as the Knowledge Valorisation Platform, through the production, testing and improvement of best practices and lessons learned in two European territories: Alicante in Spain and Emilia Romagna in Italy. In each territory, quadruple-helix stakeholders from the research & innovation ecosystem will be involved in the co-design and implementation of co-valorisation, exploiting ongoing knowledge valorisation processes such as developing innovative solutions to address the lack of raw materials and its impact on citizens’ welfare (Alicante), or specific funding schemes and projects to introduce multi-stakeholder engagement in public-funded research (Emilia Romagna).The transfer of best practices and skills will be guaranteed by a comprehensive scheme of capacity building, peer learning and shadowing opportunities, both at local and international level. The involvement of umbrella organisations such as EBN, ERRIN and universities alliances will foster a wider uptake of CO-VALUE’s trainings and tools, thus supporting the implementation of new practices by knowledge valorisation agents beyond the project consortium. Incentives for researchers to engage with society, and for society to engage with researchers will be co-designed with stakeholders in each territory and implemented throughthe involvement of local R&I public administrations. Tangible changes in local co-valorisation agents will be exploited to showcase improvements, together with a co-assessment of enabling conditions, processes and impact performed together by all stakeholders involved.

Keywords: co creation,co valorisation,open innovation,knowledge valorisation,experimentation,citizen engagement
Full-scale Demonstration of Replicable Technologies for Hydrogen Combustion in Hard to Abate Industries: The Aluminium use-case (H2AL)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Hydrogen
Action type: Innovation actions
Partnership: CLEANH2 (JU-JTI)
Countries involved: Belgium,Italy,Germany,Spain
Call: Hydrogen for heat production for hard-to-abate industries (e.g. retrofitted burners, furnaces) (HORIZON-JTI-CLEANH2-2023-1, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 7005639.25
EU funding (EUR): 5993812.38
Participants: 10
Project status: SIGNED

The H2AL consortium aims to address the challenges of adopting hydrogen (H2) in hard-to-abate industries (HTAIs) through a hybrid approach using digital tools and state-of-the-art experimental techniques. The consortium will develop an integrated H2 burner and support system for a heating furnace in an HTAI, specifically the aluminium scrap recycling industry. The project will investigate the impact of H2 combustion on the furnace structure and product quality while minimizing emissions. H2AL will apply Oxyfuel combustion of H2 as combustion technology, which will be combined with low-NOx combustion techniques, most likely the flameless/MILD combustion mode. This approach will allow us to benefit from the main advantages from oxyfuel combustion while minimizing its emissions (particularly NOx). The impact of H2 combustion on the refractory materials, overall furnace structure and product quality (aluminium) will also be investigated and measures to minimize its impacts will be implemented. To ensure widespread replication and exploitation of the technology, the consortium will perform techno-economic modeling, develop guidelines for technology integration, analyze geographic information, and develop new business models. The consortium comprises 10 partners from four countries, including 4 research organizations, 5 industrial partners, and an industry association, and includes an end-user association representing the aluminium sector in Europe. The H2AL project seeks to achieve TRL7 by running a full-scale demonstration for more than six months, with at least one trial of 100h at 100% H2 and with a thermal output of at more than 2 MWth.

Keywords: oxyfuel combustion aluminium,digital tools,holistic approach,full scale demonstration
Smart Microbeads for a revitalised Gut (SMartGut)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-06-01
End date: 2027-05-31
Duration (months): 24.0
Total project cost (EUR): 194074.56
EU funding (EUR): 194074.56
Participants: 1
Project status: SIGNED

Functional gastrointestinal disorders (FGIDs) are a group of debilitating conditions affecting up to 40% of the global population, significantly impairing quality of life and driving up healthcare costs. Current treatments focus on managing symptoms rather than addressing the root causes of FGIDs, such as inflammation, increased intestinal permeability, and gut microbiome disruptions. The SMartGut project aims to develop innovative therapeutic microbeads that encapsulate probiotics within a photo-crosslinkable biopolymer-based core. To enhance functionality, SMartGut will employ the Layer-by-Layer assembly technique to create a nanoscale protective and bioactive coating on the therapeutic microbeads surface. This coating can incorporate antioxidants to reduce inflammation and improve probiotic adhesion in the gut, and targeted peptides to strengthen gut barrier function. The therapeutic microbeads will be evaluated for their structural, morphological, and physico-chemical properties, followed by assessing the release kinetics of the bioactive components of the therapeutic microbeads and the survival of the encapsulated probiotic strains in the intestine using a simulated gastrointestinal digestion test designed for both healthy adults and the elderly. This test will ensure the effectiveness of the therapeutic microbeads in reducing gut inflammation, restoring the microbiome, and reinforcing intestinal epithelial junctions to address FGIDs. Then, the therapeutic microbeads will be incorporated into food models to evaluate their stability and impact on food characteristics while preserving their bioactivity features after food storage. SMartGut has the potential to revolutionize FGID treatment by delivering a multifunctional therapeutic system that targets the core factors of these disorders. SMartGut promises significant scientific, societal, and economic impact by introducing a novel approach to FGID management and advancing the development of functional foods.

Keywords: layer by layer assembly,therapeutic delivery system,nutraceutical,gut,gastrointestinal disorders,nanocoating,probiotics,antioxidants,in vitro model,dynamic gut models,food models
Mobile Bio-Lab to support first response in Arbovirus outbreaks (MOBVEC)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Spain,Belgium,Portugal
Call: EIC Pathfinder Open 2022 (HORIZON-EIC-2022-PATHFINDEROPEN-01, 2022)
Start date: 2023-07-01
End date: 2027-06-30
Duration (months): 48.0
Total project cost (EUR): 2998500.0
EU funding (EUR): 2998500.0
Participants: 7
Project status: SIGNED

The WHO estimates that vector-borne diseases (VBD) account for more than 17% of all infectious diseases. Every year, more than 2.5 billion people are at risk of contracting dengue alone, and VBDs cause almost 1 million deaths. In the last decades several species of invasive disease carrying mosquitoes have invaded the northern hemisphere of the planet through the transport of goods, increasing international travel and climate change. In 2018 a West Nile fever outbreak transmitted by mosquitoes occurred in the EU. For this disease there are no vaccines or medications. There were 1503 cases reported in 11 countries, and 181 deaths. VBD Mobile Bio-Labs could have assisted health authorities in containing this outbreak, reducing cases and preventing deaths. Unfortunately such a system does not exist. MOBVEC will be the first VBD Mobile Bio-Lab, providing: 1- Automatic information about vector populations, obtained in real-time by smart-traps, powered by machine-learning and edge computing: insect species, sex, age, and viral infection. 2- GEOSS compliant vector risk maps of adult insects and eggs/larvae, built on field + Copernicus data; 3- GEOSS compliant disease transmission models in mosquito populations, fusing data from Copernicus, clinical and diagnostic data of reference labs, and vector risk maps; 4- GEOSS compliant citizen-science platform to reinforce the surveillance of mosquitoes using citizens as observation nodes. 5- VBD mobile bio-lab with the capacities of points 1, 2, 3 and 4 + VBD Epidemiological maps and forecast models, to be rapidly operational in the heart of outbreaks to assist first-responders. This technology will the first line of defence against disease vectors worldwide, help prevent and fight devastating disease outbreaks, and will save lives while saving millions of euros in healthcare and lost working-hours. This has never been done before, and our consortium has the interdisciplinary research capacities to make it a reality.

Keywords: mobile bio lab,copernicus,egnss,geoss,iot sensors,disease vectors,outbreaks,public health,epidemiology,vector risk maps,viral risk maps,crisis management,metagenomics,citizen science
A System for the Early Diagnosis of Skeletal Orthodontic Malocclusions (orthomobile)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Türkiye
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-08-01
End date: 2024-07-31
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

Orthodontics can correct deformities in the maxillofacial region by making growth modifications with orthopedic devices. Skeletal orthodontic deformities are divided into three; Class I, Class II, and Class III. The ideal age of intervention for these three classifications is different. Class III problems should be detected at age 7, but diagnosis is difficult even for the orthodontist at this age when symptoms are not yet discernible to the human eye. Even when the cephalometric film taken with an X-ray is analyzed, it may not be noticed by people. In addition, it is not possible to have an orthodontic examination for children all around the world before the age of 7. The main tasks carried out by our application include screening for the preliminary diagnosis by identifying symptoms in the profile photo; informing the parents; directing to the doctor, and facilitating the doctor-patient interaction. For Class III, the accuracy rate of correctly classified images was found to be 81.66%. The current prototype was created using statistical data from the Turkish population, and an application that can extract various skeletal characteristics from any given data training set is currently being developed. We intend to expand to the international market and create a training model for various races once we can diagnose Class I and Class II problems with the same accuracy.

Keywords: digital health services
Drug Hunter - drug analyzer for in situ quantitative analysis of illegal drugs in oral fluid (Drug Hunter)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Estonia
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-07-01
End date: 2024-06-30
Duration (months): 12.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

SafePAS (Safe Portable Analytical Systems) is a deep-tech start-up led by three women-scientists-entrepreneurs aiming to bring to market portable and accurate AI-based analyzers for Agri, Med, and Health Tech. We want to bring our new solution, Drug Hunter, to the drug testing market. Drug Hunter is a portable drug analyzer that measures quantities of illegal drugs in oral fluid, even in multidrug use cases. It can be used onsite by law enforcement agencies, hospitals, clinical laboratories, and workplaces. Our core technologies are capillary electrophoresis, widely recognized as a golden standard for DNA analysis, and ultrasensitive deep UV fluorescence, facilitated by AI-based expert systems. Therefore, Drug Hunter provides lab-grade accuracy for simultaneous identification and quantification of illegal drugs in oral fluid, indicating the recent drug use as well as the severity of possible drug intoxication. There are currently no reliable drug testing solutions on the market (only mainstream immunoassay tests) for onsite use, and none of them can measure the quantities of drugs in the sample. So far, the strength of drug intoxication can only be determined in a laboratory using confirmatory methods. Increasing supportive regulations are expected to boost the growth of the drug testing market in the upcoming years. Nevertheless, Drug Hunter's market launch faces multiple challenges, that should be overcome by SafePAS. The current proposal aims to map the regulatory requirements and markets' peculiarities, fitting Drug Hunter to regulations. Our initial business model will be tested and improved, the marketing strategy will be developed, tested, and validated, and the distributors', business partners, and customers' networks will be built. We will conduct pre-clinical studies with our partners, opening new customer segments such as clinical labs. WomenTech EU will help us scale up Drug Hunter's market launch and SafePAS growth.

Keywords: detection technology,toxicology,drug abuse,capillary electrophoresis,fluorescence,microfluidics,oral fluid tests,drug analyzer
Developing near-infrared persistent room-temperature phosphorescence for down-conversion OLEDs (PNIRED)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-12-01
End date: 2025-01-31
Duration (months): 26.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 2
Project status: CLOSED

The continuous progress of persistent room-temperature phosphorescence (p-RTP) emitting in near infrared (NIR) with high potential for long-lifetime and flexible optoelectronic applications is spearheaded by the development of novel materials. Much of this interest is also due to the concomitant advantages of the organic light-emitting diode (OLED) technology. Future OLED displays are envisioned to comprise an additional NIR pixel for imaging and security protocols. Equally such NIR OLEDs can be used as a monolithically manufactured light sources in bioimaging applications. However, limited by the energy gap law, the majority of p-RTP materials emit in the visible region, NIR phosphors are rarely reported. To solve this challenge, this project aims to progress along two clear research directions: i) engineering efficient NIR p-RTP emissive material systems and ii) developing well-performing (persistent) NIR OLEDs. To construct NIR p-RTP material systems, we will put in action work packages (WPs) 1-2 by employing available organic materials to engineer host/guest emissive systems with high efficiency and stability. The correlation of their photophysical properties to the molecular microenvironment will also be investigated using the state-of-the-art spectroscopy methodologies to elucidate the mechanisms. WPs 3-4 will use established OLED fabrication routines to develop efficient NIR down-conversion OLED pixels with persistent emission and transfer the knowledge to an industrial R&D environment. The multi-disciplinary project will bridge the gap between the fundamental material research of NIR p-RTP emission and the monolithic integration of these systems in actual OLEDs as down-conversion layers for advanced sensing applications through joint research in physics, engineering and material science. I can perfectly bring in my existing skills, further broaden my expertise substantially and foster academic and industrial connections to build my future career network.

Keywords: near infrared,room temperature phosphorescence,organic light emitting diodes,down conversion
Wireless deep BRAIN STimulation thrOugh engineeRed Multifunctinal nanomaterials (BRAINSTORM)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Research and Innovation actions
Countries involved: Germany,Croatia
Call: Hop on Facility (HORIZON-WIDERA-2023-ACCESS-06, 2023)
Duration (months): 48.0
Total project cost (EUR): 559750.0
EU funding (EUR): 559750.0
Participants: 2
Project status: SIGNED

BRAINSTORM will introduce an innovative, scalable, wireless, multimodal nanoinvasive neuromodulation technology suitable for independent and switchable excitation and inhibition of deep brain neurons. BRAINSTORM breakthrough relies on novel smart anisotropic magnetic nanomaterials (SMNs) acting both as nanoscale ‘heaters’ and as ‘torquers’ by leveraging either hysteretic losses under kHz frequencies or transitions from vortex to in-plane magnetization under Hz frequencies. Intrinsic bimodal functionality that permits direct control of thermosensitive or mechanosenitive neurons, will be boosted by advanced polymer functionalization to transfer torques to electrical signals trough piezoelectric coating, and to enable transport and delivery of viral vectors to targeted neurons for genetic targeting with sensory channels. SMNs will also be steered to endogenous sensory channels relying on antibody targeting. Selected actuation of ion channels that respond to thermal or mechanical stimulus will permit selective activation or inhibition of targeted neuronal populations identifiable by magnetic resonance imaging. Advanced driving electronics will include to metamaterial solenoid coils for rapid frequency switch for control of ‘mechanical’ or ‘thermal’ functionality while focused ultrasound will facilitate non invasive delivery of SMNs in the targeted brain area. The ability of the BRAINSTORM platform to shape behaviour and demonstrate therapeutic potential by modulating the excitation/inhibition balance through thermal/mechanical/electrical modalities will be demonstrated in mouse models of Fragile X syndrome.

Keywords: advanced functional nanomaterials,biomaterials engineering,smart and responsive polymer coatings,targeted neuromodulation,wireless stimulation
TWINNING FOR RESEARCH EXCELLENCE IN SUSTAINABLE DEVELOPMENT (TWIN2SUSTAIN)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Panel: Economic Sciences
Countries involved: Cyprus,Netherlands,Belgium
Call: Twinning Bottom-Up (HORIZON-WIDERA-2023-ACCESS-02, 2023)
Start date: 2024-10-01
End date: 2027-09-30
Duration (months): 36.0
Total project cost (EUR): 1499993.75
EU funding (EUR): 1499993.75
Participants: 3
Project status: SIGNED

Cyprus is a hotspot of the climate crisis with the effects being more intense and difficult to cope; to that end, climate change in the Eastern Mediterranean, Middle East and North Africa (EMMENA) region has been an object of extensive research. However, this research did not address to a satisfactory extent the societal aspects of climate change in the EMMENA region that fall under the Sustainable Development (SD) field. Although being very active in relevant research areas of Sustainable Development and in particular, water, renewable energy and oceanography, UCY has not achieved to address the socioeconomic aspects of Sustainable Development research. It is rather positioned in a fragmented fashion in the SD research field by having research teams involved in relevant projects and undertakings but not in a concerted way, thus currently tackling important research topics sporadically and without coherence. This gap is not limited to climate change-related fields but on other aspects of SD such as gender equality, innovation law, science diplomacy and economic development, poverty reduction and income inequalities. The TWIN2SUSTAIN project aims to address this gap in this crucial research area by facilitating a partnership with two advanced partners in the SD field, UNU-MERIT and UANTWERP, in order to advance and consolidate in a multidisciplinary context all related research activities at the University of Cyprus (UCY), with main focus on the socioeconomic aspects of SD. This vision will be realised by applying for a Horizon Europe/Twinning grant, in conjunction and under the aegis of the Research and Innovation Service of UCY and with many different UCY academic departments and research units engaged. By linking UCY with these internationally leading partners in SD, TWIN2SUSTAIN will stimulate research excellence and international visibility of UCY, while improving the networking efficiency and innovation in this growing and very important field.

Keywords: sustainable development,innovation law,gender equality,science diplomacy,economic development,un sdgs,environmental protection,poverty elimination