Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Coastal flood risk in Europe and the socio-economic impacts in a changing climate (CRISIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

A large portion of the coastal population worldwide, including Europe, is already vulnerable to extreme high sea level events. In the future it is expected that climate change will increase coastal flood risk making costly adaptation inevitable. In order to help develop robust and flexible coastal management strategies, decision makers need to explore how, when, and where future changes in the physical environment will require immediate action. This is aggravated by the existence of large uncertainties in climate projections. Impact assessment models, such as the Dynamic Interactive Vulnerability Assessment (DIVA) model, have been used extensively to assess the socio-economic impacts associated with coastal flooding under climate change and to explore the benefits of mitigation, adaptation, and migration. However, because the DIVA model is applied at broad scales, it is based on a number of significant assumptions. Most notably, present-day return water levels (one of the key forcing parameters in the model) were derived using a simple global approach. Moreover, decadal variations in storminess and associated changes in future return water levels were ignored. Storm surges and river floods were assumed to be fully independent and vertical land movement rates were approximated with a global glacial isotactic adjustment model ignoring other potential contributors, such as land subsidence associated with ground water extraction. These shortcomings will be specifically addressed within the fellowship at the European level. The results will be used along with existing data bases and model infrastructure to develop a regional version of DIVA. The latter will be applied to perform the most comprehensive and realistic (in terms of temporal variations) mesoscale flood risk analysis of the European coastline to date, accounting, throughout the fellowship, for the full range of inherent model and scenario uncertainties.

Keywords: coastal flood risk,storm surges,vertical land movement,extreme value analysis,multidecadal variability,socio economic impact modelling,adaptation pathways,robust decision making
Drone-based integrated monitoring system for early detection of crop pathology and pest control in high tech greenhouse agriculture. (GIDROM)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: Italy
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-1-2015, 2015)
Start date: 2015-09-01
End date: 2016-01-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

Target market of GIDROM project is Greenhouse (Gh) Agriculture. A main problem of Gh farmers is monitoring the Gh environment to control plant diseases. Unchecked plant pathologies cause extensive crop damage and direct losses to farmers up to 15% of yearly incomes. The cost of pesticides and chemicals application is €2.000-5.000 / ha x year. Worldwide area dedicated to Gh agriculture production is about 800.000 ha of which 20% (160.000 ha) is situated in Europe (mainly in Spain, Turkey, Italy, Greece, Netherlands, France). The disruptive innovation technology proposed by the GIDROM project is the use of drones in Gh monitoring. The project partnerss ABO DATA and GLOBI HI-TECH have been jointly developing a innovative drone-based system, giving a total non-invasive, flexible and low cost approach to monitor autonomously and precisely the critical areas of the cultivar inside a Gh. The business potential of the technology is estimated > 18M€ with at least 700-800 GIDROM drone-based monitoring systems installed in Europe within 5 years from first commercialization. Feasibility assessment goals of SME Instrument (Phase I) are the elaboration of the comprehensive business plan and industrialization development plan, selection and contacts with end-users and business partners. Short-medium term objective (during SME Instrument Phase II) is to bring the GIDROM technology from readiness TRL 7 to TRL 9 (actual system proven in operational environment). The expected outcomes of the project, after completion of Phase II, are: 1. pilot demonstration of the system for routinely monitoring of crops 2. definition of a sound business model for the commercialization of the technology in Europe 3. the establishment of strategic alliances with key stakeholders to get involved for a successful commercial exploitation 4. to start-up a new Company (joint venture from ABO DATA and GLOBI HI-TECH) to move towards Phase III of the SME Instrument

Keywords: drone,crop pathology,pest control,greenhouses,feasibility analysis,piloting
WISH – Wearable Integrated System for Early Detection of Preterm Labour (WISH)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Belgium
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-2-2016-2017, 2017)
Start date: 2017-11-01
End date: 2021-10-31
Duration (months): 48.0
Total project cost (EUR): 1798562.5
EU funding (EUR): 1258993.75
Participants: 1
Project status: CLOSED

Over 15 million babies are born preterm each year and over 1 million children die each year due to complications of preterm birth (PTB), thus constituting the leading cause of neonatal mortality. PTB occurs across all countries and income levels with an average rate between 6% and 12% of all births, resulting in a significant economic impact. Studies situate the overall cost per preterm birth at approximately €60,000. Bloom will reduce this burden with WISH, a complete, technology-enabled and clinically validated solution to predict and detect the onset of preterm labor. Composed of a new improved version of our award-winning wearable sensor, a specifically designed electrode patch, a consumer app, a web-based dashboard and a secure cloud data platform, WISH integrates seamlessly into the daily activities of expectant women, facilitating data for expectant women at home and for healthcare professionals in hospitals. WISH uses our latest breakthroughs in advanced signal processing methods and machine learning analytics to extract meaningful labor risk conclusions based on physiological indicators and behavioral patterns. It automatically builds a real-time comprehensive index score on the probability of labor using the data from limited monitoring sessions that can easily be conducted at home. WISH will facilitate preventive actions in pregnancies to shift the gestational age at delivery, thus reducing the economic and psychological burden of PTB and ensuring a more efficient prenatal care with technology that could potentially avoid 74% of mother and infant mortalities, according to studies from Frost & Sullivan. WISH will contribute to the clinical and academic knowledge on PTB with results that will advance research on its pathogenesis. Through pilot clinical studies, we have also demonstrated a significant 15% reduction in stress and anxiety levels, thus also contributing to the general well-being of expectant women.

Keywords: pre term birth,wearable,data analytics,point of care medical device,biomarker,uterine electric activity
International Conference on Research Infrastructures (ICRI) 2018 in Vienna (ICRI 2018)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Action type: Coordination and support actions
Countries involved: Austria
Call: International Conference on Research Infrastructures (H2020-IBA-INFRA-CONFERENCE-2017, 2017)
Start date: 2017-10-15
End date: 2019-02-14
Duration (months): 16.0
Total project cost (EUR): 448750.0
EU funding (EUR): 300000.0
Participants: 2
Project status: CLOSED

ICRI 2018 Research infrastructures are among the core enablers of competitive research alongside basic science, development and innovation to advance the frontiers of our knowledge. These research infrastructures are often operated by international consortia and are applicable in various disciplines and stakeholder communities. Research infrastructures are constantly under pressure to adapt due to the advancements in science, research and technology. All these aspects underline the importance of research infrastructures but at the same time demonstrate the challenges and the complexity that occur within the construction, implementation, operation, funding and international cooperation. This calls for an exchange and discussion on an international level regarding topics such as governance, operations and the general policy area for research infrastructures. Respecting the need for international attention to the aforementioned policy area, the ECRI was vital towards establishing a conference format that can lead a new millennium onwards. Subsequently, the focus was widened to an international level (ICRI). The overall objective of this proposal is to organize and further establish this dynamic international forum on research infrastructures (ICRI), under the 2018 Austrian EU Council Presidency. The ICRI will gather relevant experts, shareholders and stakeholder communities of research infrastructures to discuss challenges and emerging trends for research infrastructures around the world. The specific objectives of the proposed action are as follows: - Addressing issues of global interest Development of global research infrastructures Long-term sustainability Innovation potential of research infrastructures Access and exploitation of data produced by research infrastructures - Enhancement of international cooperation - Promotion of Europe’s further strategic outline on research infrastructures - ESFRI Roadmap 2018.

Keywords: international conference,research infrastructures,global,austrian eu council presidency 2018
Computational Hematopathology for Improved Diagnostics (CompHematoPathology)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-06-01
End date: 2025-05-31
Duration (months): 60.0
Total project cost (EUR): 1981213.0
EU funding (EUR): 1981213.0
Participants: 1
Project status: SIGNED

Identifying hematologic malignancies still relies on the time-consuming and subjective visual assessment of images. Every day, cytologists and pathologists are confronted with rare diagnostic cells, ever-increasing image data, and heterogeneous disease manifestations. Although we understand blood better than any other human tissue, we are unable to quantitatively predict a patient’s blood dynamics from a measurement. Diagnosis thus depends on rough staging schemes and the expertise and intuition of the clinician. In my proposal, I address these challenges by establishing computational hematopathology, a combination of artificial intelligence algorithms and mathematical models that will boost the currently prevailing manual assessment. Based on my experience in using these methods for scrutinizing stem cell differentiation I will combine the power of deep learning and mathematical modeling with digitized and expertly annotated image data. My unique approach enables me to design and parametrize a data-driven model to predict hematopoietic dynamics in health and disease. Since the interpretation of digitized slides is becoming the clinical standard, novel algorithms for standardized disease classification and improved diagnosis are critically needed now. This interdisciplinary project merges methods from digital pathology, machine learning, image processing, and mathematical modeling. ComHematoPathology will provide novel approaches and software tools for automated classification of hematopathology image data, allowing for reproducible and precise diagnosis at an unprecedented level. This will increase throughput and standardize the diagnosis of blood diseases and will thus improve the treatment of patients suffering from hematologic malignancies.

Keywords: computational pathology
The Global Qur’an. Shared Traditions, Imperial Languages and Transnational Actors (GloQur)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2020-05-01
End date: 2025-04-30
Duration (months): 60.0
Total project cost (EUR): 1980000.0
EU funding (EUR): 1980000.0
Participants: 1
Project status: SIGNED

This project looks at Qur’an translations as a central medium through which Muslims across the globe today approach their faith. Since the early 20th century, Qur’an translations have been produced in nearly all languages read by Muslims by a variety of individual and institutional actors across nation-state borders. GloQur aims to elucidate three major transnational dimensions of the burgeoning field of Qur’an translation and their interdependence. First, it will examine transnational governmental and non-governmental actors in the field as well as the translations produced by them. Second, it strives to transcend the simple dichotomy between Arabic and ‘vernacular’ languages by analysing, from a historical perspective, the complex centre-periphery structures created by the spread of European languages such as English, French and Russian. Third, we will study the negotiation and reconstruction of a shared exegetical heritage in various linguistic, social and ideological settings. We will examine the conditions in which translations were and still are commissioned and produced, the literary history and ideological backdrop of translations, the translators’ decisions as they become manifest in the texts and their use by local audiences. By studying the role of Qur’an translations in specific Muslim communities, as well as their use in social media, we seek to shed light on the linguistic, cultural and religious significance that is attributed to them and on the processes through which specific translations are elevated to a position of authority. GloQur will thus bridge the gap between philological, historical and anthropological approaches to modern and contemporary Muslim engagement with the Qur’an. By developing an analytical framework for understanding the translation of a sacred text as a transnational religious, social and political practice, the project will break new ground in understanding the global dynamics of contemporary Islam.

Keywords: qur anic studies,islamic studies,translation,history of media,reading studies
NOvel TImber CompositEs for Energy and seismic Upgrading of Buildings (NOTICE-EUB)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Belgium
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-03-01
End date: 2023-02-28
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: SIGNED

This research project aims at developing novel timber composite systems for the combined seismic and energy retrofitting of existing building envelopes. Buildings in the European Union (EU) are responsible for 40% of the overall power consumption and 36% of energy-related carbon dioxide emissions. Meanwhile, nearly half of the structures in the seismic regions of the EU exhibit substandard seismic resistance, posing a severe threat to life safety and economy. The poor seismic performance of old buildings in the recent earthquakes in Italy and Greece caused significant economic losses, injuries, and loss of human lives. Currently, the annual cost of repair and maintenance of the European building stock is estimated to be approximately 50% of the total construction budget, exceeding €300 billion. Replacing the old buildings with new ones entails considerable financial, environmental, and social cost, which cannot be undertaken; therefore, extending the service life of buildings requires structural upgrade innovations that reduce their seismic vulnerability and boost their energy efficiency at the same time, and in the least expensive and invasive way possible. NOTICE-EUB explores a cost-effective retrofit approach, which combines advanced thermal insulation materials with engineered wood panels to provide simultaneous seismic-plus-energy upgrading. The proposed retrofit concept takes advantage of the high structural performance of the emerging cross-laminated timber (CLT) technology and the superior thermal properties of advanced insulation materials. The research activities comprise experiments on components and a full-scale building specimen to validate the efficiency of the advanced CLT systems, and to provide data for the calibration of numerical models. State-of-the-art analyses will evaluate the economic benefits of the proposed hybrid retrofit scheme. The final stage of the project envisages drafting of retrofit design guidelines and recommendations for the integrated interventions, as a contribution towards the development of new standards for the joint energy upgrading and seismic strengthening of the EU building stock.

Keywords: integrated building retrofit,energy efficiency,seismic resistance,cross laminated timber,advanced insulation materials,masonry buildings,reinforced concrete buildings
The molecular basis of ineffective erythropoiesis in Sickle Cell Disease (InEr-SICKLE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-02-01
End date: 2024-01-31
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: SIGNED

In this project, I will investigate ineffective erythropoiesis as a contributing factor and potential therapeutic target in the pathogenesis of sickle cell disease (SCD), one of the most prevalent genetic disorders in man and a global health problem. I will employ cutting-edge proteomic and genomic approaches to investigate in detail deregulation of the master erythroid transcription factor GATA1 as a result of oxidative stress in sickle red blood cells, as the basis for ineffective erythropoiesis in SCD. I will also investigate whether restoring GATA1 functions can alleviate ineffective erythropoiesis, thus providing alternative therapeutic opportunities in treating SCD. Lastly, I will generate novel cellular models for SCD from patients that can be used in dissecting the pathophysiology of SCD and in screening for agents that can alleviate IE and sickling. My project will generate novel insight into SCD pathogenesis and tools that can lead to the development of novel therapeutic approaches. My background in SCD cellular pathophysiology is highly complementary to those of my supervisors, Prof. John Strouboulis who is an expert in GATA1 functions in molecular erythropoiesis and Prof. David Rees, who is a world leading clinician in pediatric sickle cell disease. I stand to benefit greatly by receiving excellent training in -omics, functional assays in molecular erythropoiesis and in clinical aspects of SCD, that will enable me to progress into a career as an independent investigator.

Keywords: sickle cell disease,hematology,erythropoiesis,transcription factors
Gold(I)-Catalyzed Polymerization of Acetylene Gas (GASGOLD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-09-01
End date: 2024-08-31
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: SIGNED

GASGOLD aims for the development of efficient Au(I)-catalysed methodologies for the challenging intermolecular synthesis of important monomers, oligomers and polymers of acetylene gas. Au(I)-catalysts allow for the formation of cyclopropyl Au(I)-carbenes after reaction with an alkyne and alkene. The carbenes are reactive towards rearrangement to form 1,3-dienes, which are important building blocks for a range of natural and other important products, such as synthetic rubbers. Preliminary results show that further reaction of certain 1,3-dienes with acetylene can occur, forming oligomeric derivatives and this reactivity will be harnessed and further exploited in this project. Initially, the development of an effective protocol for the synthesis of a wider range and more challenging substituted 1,3-dienes from acetylene gas, both in monomeric and oligomeric forms, will be established. The reaction mechanism determining the configuration of the alkenes will be studied, for example by kinetic monitoring and isolation of reaction intermediates, to explain the observed selectivity, potentially synthesise other isomers and improve on the reaction conditions and catalyst design. The initial results will inspire the challenging selective expansion of 1,3-dienes with acetylene to form substituted 1,3,5-hexatrienes. Additionally, the unprecedented use of both acetylene and ethylene gas in Au(I)-catalysis will be explored for the synthesis of polyacetylene derivatives, which are highly important materials with electrical conductivity, as well as in the purification of ethylene gas. The development of this project offers an innovative solution for the long-standing problem of utilising acetylene gas as a simple building block in Au(I)-catalysis, offering a clear advantage over the current state-of-the-art of the field. Furthermore, the expected synergistic performance between the experienced researcher and the host group, will maximise the potential for success of the project.

Keywords: au i catalysis,acetylene oligomerisation and polymerisation,alkyne and alkene activation