Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
SCALABLA: a platform for elastic multimedia communications enabling natural social interaction and personalization (SCALABLA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Spain
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-06-01
End date: 2016-10-31
Duration (months): 5.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The mobile phone service is the most popular IT service worldwide with more than 5 billion users. However, many analysts agree that a novel wave of technologies combining WebRTC with Cloud Computing, is going to disrupt it bringing a new media communications era. This opens a multi billion business opportunity and developers are the key to it: currently, more than 10 million developers worldwide are avid of new platforms enabling innovative media services. In this project we present SCALABLA: a technological platform that makes possible for developers to create professional WebRTC multimedia services adapted to vertical domains (e.g. e-health, e-learning, social TV, etc.) For attracting developers, SCALABLA shall be accessible with lower costs and shall offer three differential features: social scalability, which enables new social communication topologies currently not available; personalization, including the ability of enriching and customizing video streams accordingly to users’ needs and context; and DevOps, which means that the platform simplifies most of the tedious tasks developers need to execute. SCALABLA is built on top of FIWARE technologies, which have been demonstrated in operational environments, and which guarantees its technical feasibility. In addition, a preliminary market analysis shows huge interests in SCALABLA concepts from different relevant market stakeholders and developers as well as the ability of the platform to open a whole new “blue ocean” market filling the gap between real-time media and live media broadcasting. This project will result in an elaborated business plan providing a detailed market analysis, a commercialization plan, a financial plan and a feasibility assessment analyzing risks, IPR protection mechanisms and regulatory constraints. This plan shall provide evidence on the ability of the company to transform SCALABLA into a successful, sustainable and scalable global business.

Keywords: videoconferencing,webrtc,cloud computing,development platform,devops,multimedia,scalability,personalization,supermedia
Individual Differences in the Biological Embedding of Developmental Origins of Health and Illness in Syrian Refugee Children (RefugeeBioEmbed)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-05-31
End date: 2023-05-30
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: SIGNED

The Syrian Civil War led to the displacement of more than 5.6 million Syrians in surrounding nations, millions of whom are children. Nations around the world are striving to resolve the economic, cultural, and societal strains of accommodating an unprecedented number of refugees. The proposed project aims to begin tackling this problem by investigating experiences of Syrian refugee children to determine whether individual characteristics influence their psychological and behavioral responses to the Syrian Civil War and subsequent circumstances. The research objectives entail applying innovative, evolutionary-developmental models to explore individual differences in the ways early childhood adversity is biologically embedded and reflected in developmental milestones and mental health. The project applies strong interdisciplinary methods to the analysis of existing, high-quality data to understand the intersections of genetics, endocrinology, psychology, and behavior. The overarching goals of the project are to 1) understand individual differences in the developmental origins of health and illness, 2) identify modifiable risk and protective factors that suppress or enhance refugee mental health, and 3) inform individualized interventions to prevent and treat mental illness among Syrian—and other—displaced populations. Bringing to bear leading experts in neuroendocrinology, genetics, psychiatry, and resilience; high-quality, longitudinal data; and state-of-the-art training in genetic and hormonal data analyses, this project will showcase European excellence in innovative, interdisciplinary, and intersectoral research in child development and public health and policy.

Keywords: life history theory,differential susceptibility,developmental timing,pubertal timing,mental health,physical health,poverty,morbidity,mortality,family dynamics,refugees,adversity,stress
Encountering Diplomacy in Early Modern Southeast Asia (EcoDip-SEA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Sweden
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-05-01
End date: 2023-04-30
Duration (months): 24.0
Total project cost (EUR): 203852.16
EU funding (EUR): 203852.16
Participants: 1
Project status: CLOSED

This research project is a study in global history. It explores how diplomatic practices and foreign relations were shaped in the pluralistic, multi-centric, open geography of maritime Southeast Asia during the seventeenth and eighteenth century. In this period, exchange between local polities and aspiring European colonial powers flourished. The project uses the rich history of negotiations and cross-cultural communication between local Southeast Asian polities and various actors from Europe to integrate practices of balancing power relations and local indigenous traditions into a nuanced global history of diplomacy. Although foreign relations are widely regarded as an important vector for cultural exchange, and while embassies have emerged as a favoured site for studying cultural encounters, little is known about the ways in which transregional interactions shaped the very principles and practices of diplomatic dealings over the course of this transformative period. The project will introduce the concept of the diplomatic encounter which allows to study relevant processes and practices in their own time and under consideration of their specific political culture. It compares different acts of negotiation including the foreign relations of insular Muslim chiefdoms, colonial rivalries, the diplomatic strategies of small city states and the impact of expanding empires in the region. Re-addressing early modern diplomatic encounters in South East Asia in diverse sources written in various languages will thus serve to overcome binaries in diplomatic history and ultimately contribute to a new narrative of diplomatic history as demanded by leading scholars in the field. The project will be hosted at the Centre for Concurrences in Colonial and Postcolonial Studies, a leading interdisciplinary research environment with an existing and steadily growing focus on Southeast Asia.
Dressing Robotic Assistants for Persons with Reduced Mobility (DRAPer)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 170121.6
EU funding (EUR): 170121.6
Participants: 1
Project status: CLOSED

Physical disabilities due to illness, injury, or ageing can alter the way a person moves around the house, manipulates objects and senses their home. These issues make it harder for persons to execute daily home activities on their own, and therefore specialized professionals are required to take care of them. However, the growing elderly population and the persons having basic activity difficulties or suffering from long-standing diseases are saturating the health systems due to insufficient infrastructures and over-demand for health carers. Robotics-based solutions are a promising alternative to support the human labour at health care. This project focuses on how robotic assistants can be exploited to provide independence and empower people with different kinds of mobility problems. Specifically, the main goal is to assist these persons in dressing themselves, which has been found to be an important task for independent living. In this sense, a robotic dressing assistant needs to skilfully manipulate clothes, physically interact with the human, recognize his/her intentions and actions, and easily adapt to changes in the clothing, user posture, and degree of mobility of the assisted person. These highly complex features are tackled in this proposal from a robot learning perspective, in which programming-by-demonstration, reinforcement and interactive learning will be combined to create both sophisticated manipulation skills and safe assistance behaviours. The proposal envisions three different real experimental scenarios to test the proposed approaches and show their performance with real (able-bodied) participants (with restricted motion). This project will not only advance the state of the art in assistive robotics, robot learning and human-safe control, but also will play a major role in helping persons with reduced mobility to live independently for longer and with a better quality of life.

Keywords: robot learning,robotic assistant,programming by demonstration,human robot interaction,physical human robot interaction,reinforcement learning,interactive learning,deformable objects
Patient specific biomimetic materials for bone regeneration (Bone3Dmatch)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-05-01
End date: 2022-09-30
Duration (months): 41.0
Total project cost (EUR): 1136914.0
EU funding (EUR): 795839.8
Participants: 1
Project status: SIGNED

Over 2 million bone grafting procedures are performed annually worldwide nearly half of them in the EU, being the 2nd most transplanted tissue after blood. Bone defects pose a great clinical and socio-economic problem, only worsening with the ageing population. Even if bone harvested from the patient, bone banks or animals are common standard, they present serious disadvantages (limited availability, immune responses, disease transmission, ethical issues). Various synthetic bone grafts have been developed to minimize complications, yet with low success and failing to accelerate natural bone growth. Bone3Dmatch revolutionizes the market of bone grafting (3.2bn€ globally) with a new generation of synthetic biomaterials. Two main disruptions are brought forward: 1) Biomimicry: The biomaterial, its aqueous composition and low-temperature processing is capable of mimicking the bone creation conditions. Thus, it is recognised as natural bone by bone cells, accelerating the bone regeneration and the patient’s recovery. 2) Patient customisation: Through advanced 3D printing technologies, it manufactures patient-specific scaffolds in less than 72h. This enables the treatment of complex bone defects, changing the current paradigm to a patient specific treatment. The company behind Bone3Dmatch is MIMETIS, a young SME built on the back of 25 years of research and business acumen in biomaterials for bone regeneration. Currently, MIMETIS offers biomimetic granules for the dental market. With an investment of 1.1M€, Bone3Dmatch will accelerate the market introduction of the 4th generation biomaterial in a completely new form (3D-printed scaffolds). Targeting orthopaedics and cranio-maxillofacial, we expect to reach the market in 2020 achieving 4,9M€ in revenues in only 3 years. Moreover, our ambition is to deploy a decentralised model where hospitals around the world are able to print their own patient-specific implants using our biomimetic biomaterial.

Keywords: biomaterial,biomimicry,bone graft,orthopedic,cranio maxillofacial,dental,3d printing,bone regeneration,regenerative medicine,additive manufacturing,patient specific,scaffolds
Bioenergetics in microalgae : regulation modes of mitochondrial respiration, photosynthesis, and fermentative pathways, and their interactions in secondary algae (BEAL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Belgium
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-06-01
End date: 2021-11-30
Duration (months): 66.0
Total project cost (EUR): 1837625.0
EU funding (EUR): 1837625.0
Participants: 1
Project status: CLOSED

During the course of eukaryote evolution, photosynthesis was propagated from primary eukaryotic algae to non-photosynthetic organisms through multiple secondary endosymbiotic events. Collectively referred to as “secondary algae”, these photosynthetic organisms account for only 1-2% of the total global biomass, but produce a far larger part of the global annual fixation of carbon on Earth. ATP is the universal chemical energy carrier in living cells. In photosynthetic eukaryotes, it is produced by two major cellular processes: photosynthesis and respiration taking place in chloroplasts and mitochondria, respectively. Both processes support the production of biomass and govern gas (O2 and CO2) exchanges. On the other hand, anaerobic fermentative enzymes have also been identified in several primary and secondary algae. The regulation modes and interactions of respiration, photosynthesis and fermentation are fairly well understood in primary green algae. Conversely, the complex evolutionary history of secondary algae implies a great variety of original regulatory mechanisms that have been barely investigated to date. Over the last years my laboratory has developed and optimized a range of multidisciplinary approaches that now allow us, within the frame of the BEAL (BioEnergetics in microALgae) project, to (i) characterize and compare the photosynthetic regulation modes by biophysical approaches, (ii) use genetic and biochemical approaches to gain fundamental knowledge on aerobic respiration and anaerobic fermentative pathways, and (iii) investigate and compare interconnections between respiration, photosynthesis, and fermentation in organisms resulting from distinct evolutionary scenarios. On a long term, these developments will be instrumental to unravel bioenergetics constraints on growth in microalgae, a required knowledge to exploit the microalgal diversity in a biotechnological perspective, and to understand the complexity of the marine phytoplankton.

Keywords: endosymbiosis,algae,oxygenic photosynthesis,mitochondrial respiration,anaerobic fermentation
STRengthening MARritime Technology Research Center (STRONGMAR)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Spain,Belgium,United Kingdom,United Kingdom,Portugal,Portugal
Call: Twinning (H2020-TWINN-2015, 2015)
Start date: 2016-01-01
End date: 2018-12-31
Duration (months): 36.0
Total project cost (EUR): 999203.75
EU funding (EUR): 999203.75
Participants: 6
Project status: CLOSED

INEST TEC is strongly committed to become a center of excellence in maritime technology and, in particular, deep sea technology. It is strategically located, with fast access to deep sea, it has been steadily building up its skills, capabilities and resources, and is presently in the process of implementing an open research infrastructure, thus preparing itself to become capable of providing services and open access to the European academic and industrial communities and, thus, become a recognized European maritime research asset. This proposal thus aims at creating solid and productive links in the global field of marine science and technology between INESC TEC and established leading research European institutions, capable of enhancing the scientific and technological capacity of INESC TEC and linked institutions (as well as the capacity of partnering institutions involved in the twinning action), helping raising its staff’s research profile and its recognition as an European maritime research center of excellence. These objectives will be fulfilled through a set of measures: summer schools; winter schools; short-term scientific meetings; Long-term Staff visits; Networking meetings; Workshops; Conferences; technology transfer workshops with stakeholders; and other dissemination activities. Therefore this proposal addresses the challenges raised in the call H2020-TWINN-2015. In particular, it takes INESC TEC, a top level Portuguese institution, and places it as the pivot of a network of excellence, involving four European Partners which are international leaders in deep sea technology. By tackling the call challenge with the specific topic of deep sea technologies, STRONGMAR is aligned with several National and European priorities (“The Portuguese Strategy for Smart Specialisation” (2014); Portuguese “National Ocean Strategy” (2013); EU Commission’s Atlantic Strategy (2011), etc.) establishing a consolidation path of INESC TEC's strategy in these areas.

Keywords: maritime technology,deep sea,sensors,endurance and long term navigation,communications and structures and manipulators
DrugSynergy: A data-driven systems biology approach to optimize drug combination strategies (DrugSynergy)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: France
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-09-01
End date: 2018-02-28
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The complex physiopathology of human chronic diseases includes networks robustness, feedback loops, and cross-talks, which may induce limited efficacy, resistance, and/or excessive toxicity of an individual drug. Learning how to combine drugs in order to improve treatment efficacy and lower undesired toxicity is a major biomedical challenge. Current strategies for drug repositioning and optimization of drug combinations have two man limitations: 1) they mostly use public data and databases, which are based on knowledge of individual drug stimuli and do not specifically analyze interactions, 2) they consider limited number of cellular outputs to analyze the response to a drug. In DrugSynergy, we will use an innovative systems biology large-scale data-driven approach to determine the interaction between two drugs at the highest possible resolution. Our computational analysis workflow has been extensively validated over the past years. It is now robust enough to be applied for the optimization of drug combinations. Our business development strategies will follow several possible non-exclusive scenarios: 1) service providing to pharmaceutical and biotech companies to optimize their own pipeline of drug combinations, 2) generate intellectual property (IP) through identification of new drug combinations, optimization of existing drug combinations by addition of innovative drugs through screening of small molecule libraries, including from our Institute. These goals will be achieved in an academic structure, through licensing new IP to industrial partners, or within a start-up company created around the innovative pipelines and know-how of DrugSynergy. These options will be explored with our business development and industrial partnership department. DrugSynergy is expected to have a strong biomedical and socio-economic impact because of the growing need of efficiently combine multiple drugs to address health challenges such as cancer and chronic inflammatory diseases.

Keywords: drug combinations,chronic disease,human pre clinical models,systems biology,signal integration,data driven computational workflow,transcriptomics,biotechnology,drug repositioning
Mental health monitoring through interactive conversations (MENHIR)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Spain,Italy,Germany,Spain,United Kingdom,United Kingdom,United Kingdom
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2018, 2018)
Start date: 2019-02-01
End date: 2024-01-31
Duration (months): 60.0
Total project cost (EUR): 749800.0
EU funding (EUR): 749800.0
Participants: 8
Project status: SIGNED

Mental health is an essential component of health; however depression and anxiety are common disorders across the European Union. Many people may be described as “living with” a mental illness, and managing their own symptoms. However, they are often unsure of the thresholds for treatment, how to control their mental health, what are the best coping strategies or which resources are available to them. Conversational systems may facilitate watchful waiting and symptom monitoring, by initiating contact and symptom checking at various times of the day and night. The MENHIR project aims to research and develop conversational technologies to promote mental health and assist people with mental ill health (depression and anxiety) to manage their conditions. The participants will exchange and share their expertise toward this common objective, building a network for exchanging ideas and knowledge between Spain, Germany, Italy and United Kingdom, including academic, non-profit organizations and companies.

Keywords: mental health,depression,anxiety,mood,conversational systems,dialogue systems,chatbots,acoustic analysis,emotion recognition,wellbeing