Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Re-inventory-ing Heritage: Exploring the potential of public participation GIS to capture heritage values and dissonance (REINVENT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Ireland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-01
End date: 2018-08-31
Duration (months): 24.0
Total project cost (EUR): 175866.0
EU funding (EUR): 175866.0
Participants: 1
Project status: CLOSED

This research critically addresses the challenges pertaining to the management of cultural heritage in contested cross-border contexts in Europe. The cultural landscape of Derry~Londonderry, located in the North West of Ireland, provides the lens through which expressions of heritage values and dissonance, participatory practices in cultural heritage management, and the application of Geographical Information Systems (GIS) to mapping heritage a cross-border basis, are explored. The interdisciplinary research will result in the first cross-border ‘cultural heritage atlas’ on the island of Ireland, and the development of a public participation GIS (PPGIS) methodology and tool aimed at capturing the plurality of heritage values ascribed by diverse communities at multiple spatial scales. The knowledge generated will be embedded within local cultural heritage management and spatial planning networks and will also inform policies and practices. The proposed training-through-research will significantly enhance my skills and competencies as an experienced researcher, advancing previous cutting-edge work on heritage values and cross-border spatial planning, and equipping me with a range of new research methods, particularly ICT- and public participation-related, that are central to future innovation in cultural heritage management in Europe. Maynooth University, given the quality of the supervisory arrangements and the location of several research resources actively engaged in cross-border cooperation, provides an optimal setting for this research and for progressing to the next stage of my research career.

Keywords: heritage values,cultural landscapes,dissonance,cross border,ppgis,spatial planning
Identification and characterization of a novel damage sensor for cytoskeletal proteins in Drosophila (ActinSensor)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2019-01-01
End date: 2020-12-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Inflammation is a host response that evolved to counteract noxious stimuli that result from infection or tissue injury, and serves to return the affected tissue to homeostasis. Cell death-associated sterile inflammation is a major contributor to secondary tissue damage associated with multiple conditions such as myocardial infarction, transplantation, and stroke. Damaged tissues are thought to elicit their inflammatory effects through the sudden release from cells of endogenous Damage-Associated Molecular patterns (DAMPs) that serve to recruit and modulate the function of immune cells. In vertebrates, a diversity of molecules have been implicated as DAMPs, including ATP, uric acid, and F-actin. In mammals, F-actin is recognised as a DAMP by the C-type lectin receptor DNGR1, expressed on CD8+ Dendritic cells (DCs), that signals to favour the cross-presentation of dead-cell antigen to CD8+ T-cells. Independently of its work on DNGR-1, the host laboratory discovered that extracellular actin elicits a JAK-STAT-dependent inflammatory response in the fruit fly (Drosophila melanogaster). DNGR-1 does not have a functional homolog in fly, therefore the actin sensor remains obscure. In order to identify the molecular sensor of extracellular actin we have conducted an in silico-based screen to identify a candidate list of potential sensors. To functionally evaluate these candidates, we will conduct in vivo RNAi and in vitro gain-of-function screens in Drosophila. We will validate the role for this novel sensor in mediating sensing of extracellular actin through multiple genetic and biochemical approaches. We expect our proposal to give novel insights into the signalling transduction and immunobiology of host responses to evolutionary conserved DAMPs. We anticipate that by understanding cytoskeletal-mediated innate inflammatory responses in fly, it will provide important insights into the evolution of similar damage sensor response pathways in higher organisms

Keywords: sterile inflammation,cytoskeletal proteins,innate immunity,damage associated moleculear patterns,jak stat signalling,drosophila melanogaster,wound healing
Unlocking new VALUE from urban bioWASTE (VALUEWASTE)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable and competitive bio-based industries and supporting the development of a European bio-economy
Action type: Innovation actions
Countries involved: Spain,Spain,Spain,Spain,Spain,Spain,Belgium,Finland,Belgium,Sweden,France,Denmark,Denmark,Denmark
Call: Integrated system innovation in valorising urban biowaste (H2020-SFS-2018-1, 2018)
Start date: 2018-11-01
End date: 2022-10-31
Duration (months): 48.0
Total project cost (EUR): 10836986.77
EU funding (EUR): 8375472.25
Participants: 20
Project status: CLOSED

On average, each European citizen produces approximately 200 kg of municipal biowaste per year, representing between 118 and 138 million tonnes of biowaste annually arising in the EU. The main municipal biowaste management systems currently existing in Europe represent one-way flow systems in which materials and resources are underused, limiting its potential recovery into high-value products. VALUEWASTE proposes an integrated approach in urban biowaste upcycling for the production of high-value biobased products, developing the first complete solution to fully valorise biowaste that can be replicated across Europe. We will implement three new value chains that will use urban biowaste as raw material for its valorisation into high-value end products in a cascading process, generating economic, social and environmental benefits: food & feed proteins and other ingredients, and biobased fertiliser. VALUEWASTE will be developed at two very different European locations, Murcia (ES) and Kalundborg (DK) with the purpose of finding a solution both technical and socially adapted to the different socio-economic contexts exiting across Europe. Social initiatives will be created to increase consumer awareness and acceptance of urban biowaste-derived products. End-user products applications and new market opportunities will be demonstrated. Outcomes of the project will contribute to new standardisation, and will be useful information for EU policy makers in terms of waste management and in the adoption of new policies.

Keywords: circular economy,protein,resource efficiency,waste management,new business models,bioeconomy,consumer awareness,citizens engagement,social innovation,critical raw materials
European Training Network for InduStry Digital Transformation across Innovation Ecosystems (EINST4INE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Germany,Italy,Italy,Spain,Finland,Denmark,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 4056696.0
EU funding (EUR): 4056696.0
Participants: 7
Project status: SIGNED

European Training Network for InduStry Digital Transformation across Innovation Ecosystems (EINST4INE)

Keywords: digital transformation
Teaching and learning practices calculus in the 18th century: the case of Italian mathematics and its European dimension (LEGITIMATH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-02-01
End date: 2024-01-31
Duration (months): 24.0
Total project cost (EUR): 171473.28
EU funding (EUR): 171473.28
Participants: 1
Project status: SIGNED

The aim of this project is to rewrite the history of differential and integral calculus in 18th century Europe focusing on the processes of acquisition and circulation of teaching and learning practices and, on a broader level, to elaborate a new adaptable methodological framework integrating history of mathematics and mathematical education, oral and cultural histories in order to reconstruct the function of oral knowledge in the processes of acquiring mathematical knowledge acting in determined institutional and social contexts. In doing so, LEGITIMATH will address an under researched phase in the history of mathematics by choosing to explore a rich teaching corpus produced by several learned communities in the Italian peninsula, and chart the transnational circulation of Maria Gaetana Agnesi’s "Istituzioni Analitiche" (1748) as well as its reception outside Italy and its French and English translations. The project is interdisciplinary, crossing history of philosophy and of mathematics, mathematics education and the oral culture of knowledge, and is groundbreaking insofar as it prioritizes oral discourses and practices over internalist studies of mathematical works, and, by examining the case of Italy, it will reassess the relation between scientific “centres” and “peripheries” from the perspective of the circulation of teaching practices. This project, hosted at Ca’ Foscari University of Venice, will be pivotal for my career as it will allow me, thanks to the help of my supervisor and the special training offered by my host institutions, to strenghten my expertise as a researcher and create a permanent international network integrating historical studies of mathematics to history of science and philosophy. The project is a fundamental step for me to eventually apply for an ERC grant, and subsequently obtain a permanent research position at Ca’Foscari or in another European or Italian institution.

Keywords: history of mathematics,history of mathematics education,cultural history,oral history,calculus
Thessaly under the Kings: Religion, Society and the Politics of Multiculturalism in Mainland Greece (THESUNKIN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-10-01
End date: 2018-04-02
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

My project titled 'Thessaly under the Kings: Religion, Society and the Politics of Multiculturalism in Mainland Greece’ examines the reorganization of sacred space, the cult practices and the religious beliefs attested in Thessaly from the mid-fourth century to the second century BC. The evidence will be discussed in terms of continuity and change, from the gradual modification of the Thessalian geopolitical and urban landscapes, which was exercised by the Macedonian rulers, to the annexation of the region into the Hellenistic Kingdom of Macedonia, down, finally, to the decline of the Macedonian power and the emergence of Roman control in the region.

Keywords: ancient thessaly,hellenistic kingship,macedonian kingdom,sacred space,rituals,religious beliefs,society,multiculturalism,archaeology,epigraphy,greek literature,numismatics
Innovative active-uptake foliar nutrition technology capable of significantly reducing pesticide rates (MICROMIX-ECO-2015)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: SME instrument
Countries involved: United Kingdom
Call: Resource-efficient eco-innovative food production and processing (H2020-SMEINST-1-2015, 2015)
Start date: 2015-07-01
End date: 2015-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Crop protection measures are essential to prevent or reduce the productivity losses caused by pests and pathogens. They play a key role in achieving sustainable food production and optimising the use of agricultural resources. This proposal explores the properties of AMIXTM technology in producing inherently healthy plants and simultaneously enhancing the activity of tank-mixed pesticides, facilitating reduced application rates; addressing the call ‘SFS-8-2015’. The pressure to increase food production is a global phenomenon, caused primarily by increasing world population and climate change. Cereals in particular are in high demand for both food and animal feed purposes. By 2050, when the world population is estimated to reach 9 billion individuals, cereal production is projected to represent 3 billion tons per year. In particular, this challenge affects the EU’s ability to remain competitive and assure its food security, and makes food less affordable for the population. The largest cereal producers - France, Germany, Poland and the UK, add up to 160 million tonnes per year; at least 50% is estimated to be subject to loss of productivity due to the limitations imposed by both current and impending pesticide regulation. AMIXTM uniquely promotes the active uptake of nutrients (as opposed to passive absorption) together with tank-mixed pesticides at the leaf surface. It offers significant and easily measurable nutrient efficiency, consistent yield benefits even in the absence of a detectable nutrient deficiency, with uptake and translocation benefits over other formulation types. AMIXTM can: (i) reduce the amount of pesticide required; extend the effect of the pesticide, increase the effectiveness of less efficient or older generations of pesticides formulations. This business opportunity can support Micromix’s strategy of growing its turnover by a factor of 3, reaching a annual sales volume of 50,000 units (€11 million) by 2018, adding over 30 extra highskilled jobs

Keywords: plant health,pesticides
A simple blood test for prognosis and monitoring of patients undergoing cancer therapy. (ONCOCHECK)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Spain
Call: Supporting innovative SMEs in the healthcare biotechnology sector (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 3109948.75
EU funding (EUR): 3109948.75
Participants: 1
Project status: CLOSED

The objective of the ONCOCHECK project is to bring to the healthcare market a unique solution for cancer prognosis and monitoring which is a simple and inexpensive (<€200/test) blood test that will allow oncologists the prediction and evaluation of disease progression (monitoring) in patients affected by the great majority of cancers, with no distinction between haematological or solid tumors. The ONCOCHECK test is based on the determination of telomere length in peripheral blood, which is a blood cell marker that has been identified in the majority of cancers. The great advantage of the ONCOCHECK tests over any competing blood tests based on cancer tumor markers is that ONCOCHECK will serve for monitoring virtually all types of cancer, while competing tumor marker based solutions are useful only for a specific cancer/tumor. Therefore, Life Length´s test will offer a universal solution for cancer monitoring, with no competitors offering a similar approach. Considering the more than 35 million of people affected by cancer all over the world and that ONCOCHECK will serve for monitoring all cancer types, the business opportunity seems unquestionable. Through the ONCOCHECK project, we seek positioning our company as a leading player in the Advanced Next Generation Cancer Diagnostic Market, which was already estimated globally to generate €7.1 billion in sales in 2015 and is forecast to exceed €13.1 billion by 2020. The main market drivers are the development of less invasive and less costly tools that can contribute to a more efficient, more frequent and sustainable management of cancer. In line with this, the ONCOCHECK project will offer oncologist a cost effective solution to the current challenges in regular cancer monitoring and management.

Keywords: telomeres,cancer
Optimising the management and sustainable use of forest genetic resources in Europe (GenTree)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Germany,Spain,Italy,Italy,Austria,Finland,Greece,Lithuania,Sweden,Switzerland,Norway,Finland,Russian Federation,New Zealand,France,United Kingdom,United Kingdom
Call: Management and sustainable use of genetic resources (H2020-SFS-2015-2, 2015)
Start date: 2016-03-01
End date: 2020-02-29
Duration (months): 48.0
Total project cost (EUR): 7986747.5
EU funding (EUR): 6700000.0
Participants: 26
Project status: CLOSED

The goal of GenTree is to provide the European forestry sector with better knowledge, methods and tools for optimising the management and sustainable use of forest genetic resources (FGR) in Europe in the context of climate change and continuously evolving demands for forest products and services. To reach its goal, GenTree will make scientific, technological and implementation breakthroughs in: (i) designing innovative strategies for dynamic conservation of FGR in European forests, (ii) broadening the range of FGR used by European breeding programmes, and (iii) preparing new forest management scenarios and policy frameworks fully integrating genetic conservation and breeding aspects, to adapt forests and forestry to changing environmental conditions and societal demands. GenTree focuses on economically and ecologically important tree species in Europe, growing in a wide range of habitats and covering different societal uses and values. The major outputs of GenTree will include: (i) much needed new scientific knowledge on phenotypic and genotypic diversity across environmental gradients in Europe, (ii) improved genotyping and phenotyping monitoring tools for practitioners, (iii) updated and refined data for information systems of in-situ and ex-situ FGR collections, (iv) innovative strategies for conservation, breeding and exchanging and using diversified forest reproductive material, (v) novel outreach and science-policy support tools to better integrate FGR concerns into forest management and better implement relevant international commitments in Europe. GenTree will improve the status and use of European in-situ and ex-situ FGR collections, support acquisition, conservation, characterisation, evaluation and use of relevant FGR in breeding and forestry practice and policy, will seek to harmonise, rationalise and improve management of existing collections and databases, and will strengthen the EU strategy for cooperation on FGR research and innovation.

Keywords: in situ dynamic genetic conservation units,ex situ collections,forest tree species,forest management,stakeholder engagement
Humanities at Scale: Evolving the DARIAH-ERIC (HaS-DARIAH)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Ireland,Austria,Italy,Greece,Croatia,France,France,Netherlands,Denmark,Luxembourg
Call: Individual implementation and operation of ESFRI projects (H2020-INFRADEV-1-2015-1, 2015)
Start date: 2015-09-01
End date: 2017-12-31
Duration (months): 28.0
Total project cost (EUR): 1941576.25
EU funding (EUR): 1930139.0
Participants: 12
Project status: CLOSED

The ‘Humanities at Scale’ project will further the DARIAH ERIC’s aim to integrate digitally enabled research in the arts and humanities in Europe and beyond and to operate a platform to enable trans-national arts and humanities research. The project will help DARIAH sustain existing knowledge in digital arts and humanities in Europe and enable new one. DARIAH connects various hubs of excellence in the domain and helps them share their results and innovations. By sharing knowledge, DARIAH works proactively to enhance the reach of digital arts and humanities within the European Research Area (ERA). This proposals aims to address some critical limitations of the current model of sharing knowledge in DARIAH and of connecting the national services in digital arts and humanities initiatives in Europe.

Keywords: research infrastructure,digital humanities,eric