Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Integrated Micro-Nano-Opto Fluidic systems for high-content diagnosis and studies of rare cancer cells (CAMINEMS)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Nanosciences and Nanotechnologies
Action type: Collaborative project
Countries involved: France,Czechia,Czechia,Portugal,United Kingdom,France,Germany,France
Call:  (FP7-NMP-2008-SMALL-2, 2008)
Start date: 2009-07-01
End date: 2012-12-31
Duration (months): 42.0
Total project cost (EUR): 4599999.52
EU funding (EUR): 3551143.0
Participants: 9
Project status: CLOSED

The project aims at developing a new integrated and automated microfluidic tool for cancer cells screening. This instrument will have a reliability and power much beyond state of the art (capture yield increased by a factor from 10X to 100X and multimodal typing of the cells in 3D high resolution images), allowing earlier and more accurate diagnosis, prognosis and selection of treatments of cancers. CaMiNEMS’s new approach will involve a new generation of bio-functionalised multifunctional magnetic nano and microparticles which will be self-assembled by a Hierarchial Templated Self-Assembly mechanism into high-aspect ratio reversible arrays. For highly automated molecular typing of cancers, this key innovation will be integrated with a unique fully automated flow control system working from nanolitres to millilitres and with innovative nano-optics tools and image analysis software. Technological developments will be validated regarding the analysis of circulating tumour cells or “micrometastases” and the molecular typing of minimally invasive microsamples from tumours. The project will also yield new tools for research and drug-discovery, allowing for the first time to study at the single molecule scale in single cancer cells from patients the fate and action of new generation anticancer drugs using innovative dynamic tracking of Quantum dots. To combine research excellence and societal impact, the consortium involves research groups with complementary competences in microfluidics, nano-optics, biophysics, nanoparticles, biochemistry, informatics, several forefront cancer centres for clinical validation and a research-intensive SME for exploitation.

Keywords: nanoparticles,self-assembly,bionems,bioinformatics,nano-optics,cancer diagnosis,drug targeting
A user-oriented, knowledge-based suite of Construction Industry LifE Cycle CosT Analysis (CILECCTA) software for pan-European determination and costing of sustainable project options (CILECCTA)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: New production
Action type: Collaborative project
Countries involved: United Kingdom,Sweden,Germany,Germany,Germany,Norway,Spain,Poland,United Kingdom,Türkiye,Estonia,United Kingdom,Germany,Spain
Call:  (FP7-NMP-2008-LARGE-2, 2008)
Start date: 2009-09-01
End date: 2013-08-31
Duration (months): 48.0
Total project cost (EUR): 7805221.13
EU funding (EUR): 5967129.0
Participants: 19
Project status: CLOSED

The principal objective of the CILECCTA project is to bring together a top class consortium of academic and industrial researchers, associations and enterprises – both SMEs and LEs – to develop a suite of software that is: capable of full Life Cycle Cost Analysis (LCCA); compatible with codified Price Banks (PBs) and Life Cycle Inventories (LCIs) across Europe; customisable / configurable for whole assets and their components; and which will enable the assessment of sustainable options to provide decision support. The development of the CILECCTA concept has been propelled by four sets of drivers: Building industry drivers – The European Construction Technology Platform has published three major strategic priorities for the industry: • Meeting client/user requirements • Becoming sustainable • Transformation of the construction sector (i.e. its industrialisation) EC drivers for LCC – The EC has recommended ‘the development of a common LCC methodology at European level, incorporating the overall sustainability performance of building and construction’ to achieve sustainable building practices and improve resource efficiency. End-user / client drivers – Clients need to plan with increased certainty and require New Generation Whole Life Costing Tools and analysis of the resultant Life Cycle Options (LCOs) to achieve this Commercial drivers – The consortium members are all driven by the desire to research, improve and commercialise LCCA. To align with these drivers we have assembled a consortium of 20 partners including universities, RTOs, IAGs, LEs and 10 SMEs. They have developed a work programme over four years with the principal scientific objective of researching and developing the theory of LCCA and its compatibility with codified PBs and LCIs. The application of sustainable LCOs to real assets will be proved in three large-scale demonstration construction projects prior to dissemination and commercial exploitation of the project results.

Keywords: construction,life cycle costing,life cycle assessment,sustainability,resource efficiency
Integrated cost-effective construction process for transport infrastructures, based on a flexible industrialisation of FRP components (TRANS-IND)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: New production
Action type: Collaborative project
Countries involved: Poland,Spain,Poland,Italy,Germany,Italy,Germany,Spain,Netherlands,Germany,Slovenia,United Kingdom,Switzerland,North Macedonia,Spain,Netherlands
Call:  (FP7-NMP-2008-LARGE-2, 2008)
Start date: 2009-06-01
End date: 2013-05-31
Duration (months): 48.0
Total project cost (EUR): 9764514.0
EU funding (EUR): 6099175.0
Participants: 19
Project status: CLOSED

Polymer based manufactured components for construction applications have been designed, developed and demonstrated in European projects such as HP FUTURE-Bridge, SAFEFLOOR and MEGAWIND. The results are very promising regarding customer requirements, quality, technical and economical feasibility and the favourable impact of using this kind of composite-based components in terms of sustainability, safety and quality of life. However, there is a need to industrialise the whole construction process of the Fibre Reinforced Polymers (FRP) components in order to really achieve these results. Further integration of the entire supply and value chain is needed, as well as the development of a high technology for design and manufacturing of FRP components, to transform on-site construction to off-site manufacturing. The overall objective of the Trans-IND project is to develop a cost-effective integrated construction process that will enable the maximum capability of industrialisation of components for transport infrastructures (road and pedestrian bridges, underpass, containing walls, acoustic and safety barriers) using polymer based materials (carbon fibre, glass fibre ). It will be demonstrated, as a pilot case, for components of a bridge (beams and preslabs) due to a higher complexity in the bridge components manufacturing and assembly compared to other applications.

Keywords: industrialization process,composites materials,integration of whole value chain,design for manufacturing and assembly,business model,cost-effective,value chain
Regeneration of Cardiac Tissue Assisted by Bioactive Implants (RECATABI)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: Spain,Germany,Spain,France,France
Call:  (FP7-NMP-2008-SMALL-2, 2008)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 2929560.87
EU funding (EUR): 2328302.0
Participants: 7
Project status: CLOSED

Heart failure is the end-stage of many cardiovascular diseases, but the leading cause is the presence of a large scar due acute to myocardial infarction. Current therapeutic treatments under development consist in cellular cardiomyoplasty where myocardial cells or stem cells are implanted alone or encapsulated in natural scaffolds (collagens) and grafted onto infarcted ventricles with the hope that cells will contribute to the generation of new myocardial tissue. This approach seems to have a beneficial effect although it is not completely understood and optimized, yet. Thus, the urgent need of better therapeutic platforms is imminent. In view of this, we created a small interdisciplinary consortium (RECATABI) with experts in areas such as material sciences, tissue engineering, stem cell technologies and clinical cardiovascular research. RECATABI will integrate and synergise their capacities in order to obtain a novel clinical platform to regenerate necrotic ischemic tissues after cardiac infarct with a simple one-time patch technology application. The consortium will accomplish this by fabricating nanoscale engineered biomaterials and scaffolds that will match the exact biomechanical and biophysical requirements of the implanted tissue. In addition, the construct may induce rapid vascularization to ensure tissue remodelling and regeneration into a newly functional myocardium. The regenerative capacity of the implants loaded with pre-adapted cells (biomechanically and biophysically trained) will be assessed in small (rodents) and large (sheep) animal models.

Keywords: elastomeric membranes,smart nanomaterials,drug delivery,cellular cardiomyoplasty,regeneration
Three-dimensional nanobiostructure-based self-contained devices for biomedical application (3D-NANOBIODEVICE)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Nanosciences and Nanotechnologies
Action type: Collaborative project
Countries involved: Sweden,Denmark,Germany,Ireland,Austria,Spain,Ireland,United Kingdom,Denmark
Call:  (FP7-NMP-2008-SMALL-2, 2008)
Start date: 2009-07-01
End date: 2012-06-30
Duration (months): 36.0
Total project cost (EUR): 4862267.0
EU funding (EUR): 3548000.0
Participants: 11
Project status: CLOSED

The main scientific objective of the project is to enhance the understanding of the fundamental principles for controlling electron transfer reactions between nanoparticles (NPs), carbon nanotubes (CNTs), their assemblies confined into three-dimensional (3D) microscale networks, conductive nano/-microporous silicone (NMPSi) chips and different bioelements, such as glucose oxidising and oxygen reducing enzymes. The technological objective of the project is to construct potentially implantable microscale self-contained wireless biodevices working in different biomatrices, e.g. blood, plasma, saliva. Novel biodevices will be constructed by combination of glucose and oxygen sensitive biosensors powered by biofuel cells, all made from 3D nanobiostructured materials and operated by wireless microtransmitter/transducer system. To produce 3D microscale devices with superior characteristics mathematical modelling of their performance will be compared against experimentally determined parameters. Nanowiring of appropriate redox enzymes with NPs, CNTs, proper surface modifications, and use of Os and Ru redox complexes, are chosen as a major direction to solve main obstacles in the area of bioelectronics, i.e. poor electronic communication between the biocomponents and the electronic elements along with insufficient operational stability. The 3D structure of nanobiodevices will provide very high efficiency and stability along with their miniaturisation for successful application in biomedicine and health care. The developed, wireless self-contained and potentially implantable, 3D nanobiostructure-based devices will be used to improve quality of life and increase safety in case of widely occurring chronic diseases. Moreover, in the long-term, 3D nanobiostructure-based elements will be essential for constructing devices to be used for neuron/nerve stimulations and compensation of human disabilities.

Keywords: three-dimensional nanobiostructure,microbiosensor,microtransducer,microtransmitter,3d-bioanode,3d-biocathode,3d-biofuel cell,wireless self-contained device
Proposal for the Continuous Proliferation & Simultaneous Maturation of Haematopoietic Stem Cells into Blood Cell Lineages (REDONTAP)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Materials
Action type: Collaborative project
Countries involved: United Kingdom,Spain,Germany,Netherlands
Call:  (FP7-NMP-2008-SMALL-2, 2008)
Start date: 2010-04-01
End date: 2014-03-31
Duration (months): 48.0
Total project cost (EUR): 3581544.0
EU funding (EUR): 2747000.0
Participants: 4
Project status: CLOSED

Understanding the biological signals and their temporal magnitude involved in the division, maturation and migration of haematopoietic stem cells (HSCs) and their differentiated progeny would allow for a controlled continuous production of mature blood cells. By careful selection of a 3-dimensional micro-environment it is possible to mimic the niche within bone marrow in which haematopoiesis occurs. Further, by design and control of the flow profile within this microenvironment, it is possible to fine tune the rate of departure of the differentiating cells into a separate microenvironment suitable for further maturation, so creating the conditions for the generation of mature blood cells which could be a continuous process. This research will determine the requirements for the control of the fluidic behaviour within bioreactors for the generation of HSC. Complex, composite systems that allow for the temporal and spatial separation of microenvironments allowing for not only variation in the fluid flow and oxygen tension, but a change in the chemical nature of the culture conditions, will provide the opportunity for delivery of controlling factors. The principle is based on the ability to provide nutritional exchange with an overall zero, or very small, net mass transport. Mechanical design will allow us to match the rate of HSC division, providing the opportunity to derive the daughter cells into the correct environment for red blood cell development over an appropriate time frame. Differentiation of HSCs into different blood cell types occurs within different bone marrow niches and so mimicry of the erythrocyte niche is likely to result in maximisation of the rate of red blood cell development.

Keywords: haematopoeitic stem cells,red blood cell production,tissue engineering,in vitro
Strengthening the SOLid-state research capacities in Zagreb by the introduction of the Nuclear Magnetic Resonance method (SOLENEMAR)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Croatia
Call:  (FP7-REGPOT-2008-1, 2008)
Start date: 2009-03-01
End date: 2012-08-31
Duration (months): 42.0
Total project cost (EUR): 946380.0
EU funding (EUR): 844245.0
Participants: 1
Project status: CLOSED

The Physics Department of the Faculty of Science at the University of Zagreb (PDFS) is the leading university physics department in Croatia with 70 internationally recognized scientists and 660 undergraduate and graduate students. A considerable part of the research in PDFS is devoted to solid state physics and materials science. Given that nuclear magnetic resonance (NMR) is today an unavoidable method in solid-state physics, we aim this project at complementing the infrastructure for materials research at the PDFS by the introduction of a solid state NMR (ssNMR). With this project, we shall accomplish four tasks: (a) strengthen the human potential in solid state research, (b) purchase and install an ssNMR spectrometer, (c) further develop a cooperation with European NMR centres of excellence, and (d) make the overall research capabilities of PDFS and especially ssNMR method visible to the wider scientific community, general public, and small and medium enterprises (SME) in Croatia and South Eastern Europe (SEE). Human potential will be strengthened by: (i) specialization of young researchers in high-quality European NMR laboratories, (ii) the return of experienced researchers from abroad, (iii) the exchange of know-how and experience by secondments of senior Croatian researchers and top European NMR researchers. The promotion of PDFS will be achieved by: (i) the organisation of two workshops with targeted audience of young researchers in SEE, (ii) the organisation of seminars for industry and SME managers about the possibilities of materials research at PDFS, (iii) active participation of Croatian researchers in EUROMAR conferences and European magnetic resonance societies, and (iv) the interaction with the public media. The new ssNMR group will reinforce the overall European research area since the need for NMR investigations of new materials highly exceeds the European experimental ssNMR capacities.

Keywords: research capacities,human potential,nuclear magnetic resonance
Perception of Other Religions (POR)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: The study of the human past
Countries involved: Germany
Call:  (ERC-2008-AdG, 2008)
Start date: 2009-04-01
End date: 2012-03-31
Duration (months): 36.0
Total project cost (EUR): 579999.96
EU funding (EUR): 579999.96
Participants: 1
Project status: CLOSED

The aim of the research project is to provide an extensive analysis of the perception of other religions and their members by Christian authors of the Early and High Middle Ages from the fifth to the twelfth centuries. For the first time ever, the medieval perception of heathens, Jews, Muslims, heretics and Orthodox Christians, as they are seen by Occidental Catholics, is explored in a comparative and comprehensive manner. The project, therefore, will provide an invaluable contribution to religious thinking, the understanding of religion, the concept of "the other" and the (religious) concept of self.

Keywords: history of religion,history of perceptions
Evaluation of the Institute for Parallel Processing, Bulgarian Academy of Sciences (EVALIPP)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: International Co-operation
Action type: Coordination and support actions
Countries involved: Bulgaria
Call:  (FP7-REGPOT-2008-2, 2008)
Start date: 2009-03-01
End date: 2010-02-28
Duration (months): 12.0
Total project cost (EUR): 75480.0
EU funding (EUR): 67303.0
Participants: 1
Project status: CLOSED

The objectives of EVALIP are: to evaluate the R&D potential and assign a 'quality label' to research teams in certain well-defined ICT areas; and to develop a detailed SWOT analysis and respective Action Plan with vision for institute development in mid-terms. The 'quality label' might turn the institution to a regional unit of excellence with preparatory and complementary functions in large research clusters and infrastructures. The proposal discusses in detail the vision about the evaluation and the selection of the assessment critera. EVALIPP specifies the tasks and the main activities for the preparation of the evaluation materials. It presents the expected impact of the assessment exercize. The impact at national level is twofold: first to show to the Bulgarian funding agencies a clear evidence about the R&D quality of the research teams, and second to attract more and better PhD students as well as postdocs. The impact at international level is related to the strengthened position of the institution in the European Research Area with better opportunities for international cooperation and participation in further projects.

Keywords: information and communication technologies,parallel algorithms,computer networking,grid,nlp,signal processing
BUILDING UP MODERN BIOTECHNOLOGIES FOR AGRICULTURE (MOBITAG)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: Unlocking and developing the Research Potential of research entities established in the EU�s Convergence regions and Outermost Regions
Action type: Coordination and support actions
Countries involved: Czechia
Call:  (FP7-REGPOT-2008-1, 2008)
Start date: 2009-03-01
End date: 2012-02-29
Duration (months): 36.0
Total project cost (EUR): 1248668.0
EU funding (EUR): 972070.0
Participants: 1
Project status: CLOSED

The Region of South Bohemia, which occupies Eastern half of the convergence region CZ-NUTS 2 Southwest, lacks large industries and relies to great extent on the country-side. The Biology Centre of the Academy of Sciences (BCAS) located in the District plays important role in assessing environmental impact of various activities but contributes little to the implementation of novel technologies that would enhance and diversify productivity. MOBITAG project is the first and crucial step to rectifying the situation through the development of modern research capacities with the aid of colleagues from advanced parts of EU. This goal is directly related to the intended construction of the Biotechnological Institute of Applied Ecology. The project aims at enhancing BCAS research potential to a level allowing development and deployment of novel biotechnologies for a highly productive, environment-friendly, and sustainable agriculture. Research enhancement will target areas: (1) Genome analysis; (2) Exploitation of natural compounds; (3) Transgenosis; (4) Safety aspects of GMO. Another goal of MOBITAG is the support of managerial skills, especially in respect to FP7. Dissemination activities will be focused on the education of farmers as well as general public about contemporary agrobiotechnologies. Project results will be provided to regional authorities and higher level politicians to be used in the preparation of R&D&I plans and agricultural policy. Project goals will be achieved through (1) Recruitment of experts who are working in BCAS on temporary basis, (2) Return of experienced researchers working in USA), (3) Training of BCAS staff in EU laboratories, (4) Participation of EU scientists in BCAS research, (5) Mobility of researchers, (6) Training of research managers, (7) Acquisition of research equipment, (8) Organization of meetings, (9) Several types of dissemination activities.

Keywords: agrobiotechnology,plant transgenosis,gmo,plant protection,public awareness,sustainable agriculture
ANTS RESEARCH GROUP EVOLUTION TO A RESEARCH EXCELLENCE INSTITUTE (ANTS++)

Framework: FP7 — Capacities
Programme: Research Potential
Destination: International Co-operation
Action type: Coordination and support actions
Countries involved: Spain
Call:  (FP7-REGPOT-2008-2, 2008)
Start date: 2009-01-01
End date: 2009-12-31
Duration (months): 12.0
Total project cost (EUR): 162079.2
EU funding (EUR): 144520.62
Participants: 1
Project status: CLOSED

The ANTS research group is a dynamic and very productive research group that since its creation has been growing in members, experience, intensity and results as to become it a reference research group at regional and national level. Last year, in 2007, ANTS group has been nominated and awarded as an excellence research group in the Murcia Region. Additionally University of Murcia has prepared a call for creating research centres (called research institutes) of excellence where the potential of the research done in the University could be leveraged and transferred to the society. In order to reach this next level in the process of excellence, as a first step, a clear Action Plan for this transformation has to be defined with the advice of an External Advisory Committee of leading experts in these fields. They will analyze the strengths and opportunities of ANTS group for the future. This project is designed to produce a SWOT analysis and an Action Plan for leveraging ANTS group to the next evolution as a research centre/institute of excellence in the near future.

Keywords: excellence center,research on ict,action plan for a research institute