Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
The Environmental Exposome And Health (ENVESOME)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Living and working in a health promoting environment
Action type: Research and Innovation actions
Countries involved: Greece,Spain,Austria,Portugal,Poland,Denmark,Germany,Slovenia
Call: The role of environmental pollution in non-communicable diseases: air, noise and light and hazardous waste pollution (HORIZON-HLTH-2024-ENVHLTH-02-two-stage, 2024)
Start date: 2024-12-01
End date: 2028-11-30
Duration (months): 48.0
Total project cost (EUR): 8532742.69
EU funding (EUR): 7999798.58
Participants: 16
Project status: SIGNED

ENVESOME aims to elucidate mechanistically the role of air, noise, light, and hazardous waste pollution in non-communicable disease development. The project addresses the need to strengthen the knowledge available to policymakers regarding pollution-disease associations and causal mechanisms at different phases throughout the human lifecycle. ENVESOME proposes to develop an exposome and citizen-science-based framework for assessing the risks of emerging environmental health stressors. This will be achieved by fusing environmental monitoring and personal exposure data and models through AI tools. Human and cell biology knowledge, human biomonitoring, and in vitro data will be used to determine adverse outcome pathways and networks associated with environmental stressors. Particular focus will be paid to intersecting pathways relevant to cardiorespiratory disease; metabolic syndrome; neurotoxicity; immunotoxicity; sleep, and mental health disorders. We aim to elucidate the main sources of environmental exposure and drivers of the adverse outcomes above. This will allow for the articulation of cost-effective mitigation strategies that will be applied in select case studies. Their efficacy will be evaluated using environmental and exposure indicators together with early effect biomarkers (EEB). Methodological and technical innovations and the respective scientific evidence regarding the causal links between emerging environmental stressors and human health will be translated into policy proposals supporting the articulation of strategies for country- or city-specific, targeted and cost-effective interventions, thus promoting effective public health protection, as well as guidelines and updated limit values as needed. Environmental management for public health protection will be supported by a decision support system (for policy makers), a chatbot (for health practitioners), and a mobile app (for citizens). Training on novel tools will be given to all relevant actors.

Keywords: exposome,lifecycle,human cohorts,sensors,data fusion,biobanks,multi omics,bioinformatics,systems biology,hazardous waste,contaminated sites,precise prevention,machine learning
Track and forecast changes in marine fish population stability over time and across space (MAFIS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France,Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-05-01
End date: 2025-04-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 2
Project status: CLOSED

Marine ecosystems provide key functions and services including biodiversity and food resources. Disturbances, such as climate change and overfishing, are seriously threatening the future provision of these services and leading to collapse of marine populations. To track and forecast marine ecosystem stability has emerged as a new paradigm to understand the capacity of an ecosystem to persist a qualitatively similar state in the face of disturbances. However, three challenges prevent the advances in this research field. Most established stability measures assume stable equilibrium and constant magnitude of disturbances, while marine ecosystems are influenced by multiple disturbances simultaneously, with the magnitude of disturbances changing with time. In addition, even though population stability varies with space, most of existing work examined marine ecosystem stability at the regional scale of fishing grounds due to limitations in data and methodology. Moreover, age group interactions fundamentally affect population dynamics yet have been overlooked when quantifying population stability. In line with those reflections, this proposed research intends to develop a novel research framework to track and forecast marine population stability encompassing temporal and spatial dimensions of three key fish species of the North Sea (WP1), and to identify drivers of population stability across space (WP2). Empirical dynamic modelling will be used to track and forecast the evolution of population stability over time and across space based on age group interactions of the population, producing yearly population stability maps from 1977 to 2022 and forecast maps from 2023 onward. These results will be transformed into web-based interactive map and manual (WP3) for fisheries managers and researchers to identify the most vulnerable locations in the fishing grounds and to decide fishing quota with the overall goal of preserving stability in marine ecosystems.

Keywords: population stability,marine fish
IntEgrated protection and Restoration apprOaches for natUral Lake EcoSystems (EUROLakes)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Mission
Theme: Ocean, seas and waters
Destination: Ocean, seas and waters
Action type: Innovation actions
Countries involved: Netherlands,Romania,Italy,United Kingdom,Austria,Bulgaria,Germany
Call: European natural lakes: demonstration of integrated approaches for protection and restoration of natural lake ecosystems and their biodiversity (HORIZON-MISS-2023-OCEAN-01, 2023)
Start date: 2024-09-01
End date: 2028-08-31
Duration (months): 48.0
Total project cost (EUR): 3911193.75
EU funding (EUR): 3819768.75
Participants: 13
Project status: SIGNED

EUROLakes project proposes an innovative, holistic, and science-based approach to safeguarding and restoring European natural lakes and their ecosystems. This project builds upon the 4 Returns Framework for Landscape Restoration, a practical methodology designed to seek sustainable, long-term solutions at the landscape level, with the aim of achieving four types of returns: inspiration, social benefits, natural restoration, and financial gains. This holistic approach is realized through five key elements: establishing a landscape partnership, fostering shared understanding, collaboratively envisioning the landscape, taking coordinated action, and continuously monitoring and learning. The EUROLakes project will establish local communities of practice and, in collaboration with them, develop and showcase innovative, integrated protection and restoration solutions, with a particular focus on nature-based solutions (NBS). These solutions will be demonstrated in three specific areas: Lake Vico in Italy, Lake Bistreţ in Romania, and Lake Dümmer in Germany. Furthermore, the project will highlight the long-term potential for replication by enhancing local capacity in Denmark, Ireland, and Moldova. These approaches will be complemented by modeling activities and the dissemination of knowledge regarding nature finance, contributing to a comprehensive adaptive management strategy aimed at restoring the ecological and chemical health of natural lakes to a "good" status. In this way, the EUROLakes project will directly contribute to the objectives of various EU instruments and policies, including the Water Framework Directive, the Green Deal, and its Mission objective to "restore, protect, and preserve the health of our oceans, seas, and waters by 2030."

Keywords: lake ecosystems,landscape,protection and restoration,water management
(In)visibility of Multilingualism in Amdo Tibet (IMAT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-01-01
End date: 2025-12-31
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: SIGNED

This project will study how multilingualism and linguistic diversity are materialised in the linguistic landscape of Amdo Tibet. This region is situated in the northeast part of the Tibetan plateau and encompasses the present-day Chinese provinces of Qinghai and Gansu. The area is known for its ethnolinguistic diversity. Amdo Tibet is inhabited by several groups, such as Han Chinese (the major ethnic group in China), Tibetans, Chinese Hui (Chinese-speaking Muslims), the Muslim Turkic-speaking Salar, and Mongolic-speaking Buddhist populations. Language policies, intense urbanisation, migration, and socio-economic opportunities and imperatives have an impact on language practices and language use among ethnic groups. This project looks at these changes from the angle of language use in the linguistic landscape. This research studies ethnolinguistic diversity in space, focusing on public signs. The object of this study is the town of Rongwo, the county seat of the Rebgong (Chinese: Tongren) Tibetan autonomous county in Qinghai province (People's Republic of China), where Tibetan and Chinese are co-official languages. The town constitutes the main administrative and commercial centre of the area and features schools, administrative offices, hospitals, and different kinds of businesses such as restaurants and clothing shops). This project draws on linguistic and visual data available in public signs, ethnographically-informed data, and data on regulations of languages in space. The analysis will be based on a holistic approach that considers the informative and symbolic role of the languages involved, the language policies and ideologies at play, and language norms and language contact. The broader goal of this project is to understand the creation and management of ethnolinguistic diversity and linguistic hierarchies in urban space through languages, scripts, and other visual and semiotic means.

Keywords: linguistic landscape amdo tibet ethnic minorities in china multilingualism language policies
Solar-Driven Perovskite Tandem for Methanol Production (SUNPEROM)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Italy,France,United Kingdom,Malta,Switzerland
Call: Solar-to-X devices for the decentralized prosumption of renewable fuels, chemicals and materials as climate change mitigation pathway (HORIZON-EIC-2024-PATHFINDERCHALLENGES-01, 2024)
Start date: 2025-11-01
End date: 2029-10-31
Duration (months): 48.0
Total project cost (EUR): 3333434.36
EU funding (EUR): 2853875.25
Participants: 6
Project status: SIGNED

The SUNPEROM project aims to transform renewable energy by developing a solar-driven system for direct methanol synthesis from atmospheric CO2. The primary objective is to achieve a Solar-to-Methanol efficiency exceeding 12% through the creation of an innovative, cost-effective tandem device. This device features a high-voltage perovskite-perovskite solar conversion stack and an advanced near-infrared (NIR) photocatalyst-mixed gas diffusion layer for efficient CO2 capture and conversion, utilizing the full solar spectrum. Taking a high-risk, high-reward approach, SUNPEROM targets significant breakthroughs in solar fuel production technology, delivering green methanol at a competitive price. The technology integrates diverse renewable energy components, including high-voltage all-perovskite tandem solar cells, NIR photocatalysts, solid-state CO2 capture, and direct electroreduction of CO2, representing a comprehensive approach to solar fuel production. The project emphasizes advancing cutting-edge technologies and contributing to a net-zero greenhouse gas emissions economy. To elevate the Technology Readiness Level (TRL), the project includes plans for standardized validation of the SUNPEROM tandem device, with a clear focus on moving beyond the conceptual stage towards practical implementation. Environmental and social impacts are also prioritized, with a thorough Life Cycle Analysis (LCA) planned to assess sustainability. Additionally, the proposal benchmarks SUNPEROM against current commercial technologies, aiming to surpass existing performance standards, reduce production costs, minimize land use, and achieve a low energy payback time for sustainable solar fuel production. Regulatory compliance is a key aspect, ensuring alignment with current policies for a smooth transition to commercialization.

Keywords: co2 capture,co2 to methanol,artificial photosynthesis,photoelectrochemical co2 reduction,perovskite solar cell,all perovskite tandem cell,gas diffusion layer,near infrared photocatalyst
A European Training Program to Foster the Full Therapeutic Potential of Antisense Technology across Tissues (EFFECT)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands,Spain,Portugal,France,Sweden,Belgium,Italy,United Kingdom
Call: MSCA Doctoral Networks 2023 (HORIZON-MSCA-2023-DN-01, 2023)
Start date: 2025-01-01
End date: 2028-12-31
Duration (months): 48.0
Total project cost (EUR): 3316228.46
EU funding (EUR): 2951611.2
Participants: 21
Project status: SIGNED

The EFFecT Doctoral Training (DN) Network responds to the evolving landscape of RNA-based therapeutics and in particular antisense oligonucleotides (ASO). Over the last 25 years, only 21 antisense nucleic acid-based molecules have been approved by the FDA or/and EMA. However, the field is now at the tipping point of maturity to achieve regular translation from bench to bed side, provided that certain obstacles are successfully addressed. Our consortium involves experts from academia, industry, and non-profit organizations across nine European countries with first-hand experience in the successful translation of this new technology and in-depth knowledge of the remaining hurdles for its success. With leading scientists at different career stages, EFFecT’s core is form by nine academic and three industrial partners. EFFecT's objectives include addressing tissue-specific delivery challenges, imparting knowledge on diverse ASO modalities, and creating a roadmap for ASO therapeutics in Europe. The network's composition leverages over 20 years of experience in nucleic acid drug development, and was born from the successful COST Action "Delivery of Antisense RNA ThERapeutics" (DARTER). The EFFecT training network ensures a comprehensive education for Doctoral Candidates through knowledge exchange, secondments, research workshops and dissemination. This network is expanded with the collaborations of experts in communication, intellectual property, and open science that will train the DCs in good scientific practices. By addressing training gaps and fostering collaborations, EFFecT is poised to deliver the next generation of experts in this up-and coming field, elevating Europe's visibility and competitiveness in antisense RNA therapeutics.

Keywords: antisense oligonucleotides rna based therapies genetic therapies nucleic acids delivery model systems drug development
Croatia-Cyprus Excellence Hub on Eco-Innovative Technologies for Healthy and Productive Seas (SeaTecHub)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Cyprus,Croatia
Call: Excellence Hubs (HORIZON-WIDERA-2022-ACCESS-04, 2022)
Start date: 2023-06-01
End date: 2027-05-31
Duration (months): 48.0
Total project cost (EUR): 4999577.5
EU funding (EUR): 4999577.5
Participants: 14
Project status: SIGNED

The main goal of the SeaTecHub project is to strengthen Croatian and Cyprus place-based innovation ecosystems and improve access to excellence for R&I actors by cross-border collaboration on a common strategy and alongside value adding chains within the area of eco-innovative technologies for healthy and productive seas, focusing on sectors 1. Aquaculture and fisheries, 2. Smart ports, 3. Maritime security and protection, 4. Research and Education, and 5. Maritime technologies, which are aligned with Croatian and Cypriot Smart Specialization Strategies and have been identified as emerging and established sectors in the EU Blue Economy Report 2021 . The objectives of the SeaTecHub project are: 1) to facilitate long-term cross border and inter-sectoral collaboration to advance eco-innovative technologies for healthy and productive seas, 2) to perform joint research work to close knowledge gaps, consolidate and reinforce quadruple-helix linkages, and validate strategy and action and investment plans (AIPs), 3) to implement a set of mutual learning and skills development measures, and 4) to raise visibility of Croatian-Cyprus innovation ecosystems by implementing strategic measures in the form of organizing networking, knowledge and experience transfer events. These objectives will be reached through a set of measures that include a) development of the strategy and AIPs and their digitalization through an innovative platform utilizing blockchain-based tokenization, b) R&I projects selected considering cross-border and cross-sectoral needs within, c) conceptual design and pre-planning for pilots and demonstrators, and d) a set of accompanying measures and outreach activities. The SeaTecHub consortium covers the quadruple helix of Croatian and Cyprus ecosystems: 2 research organizations, 4 public authorities, 5 business actors, and 3 NGOs. Strong willingness to actively participate has also been expressed by 49 institutions who have provided Letter of Support.

Keywords: blue economy,eco innovative technologies,healthy seas,maritime technologies
SpAce-AIr-Ground Last Mile InfRastructure & Dynamic PrOgrAmmable DistRibuted EnvIronment For Edge FArmiNg (AGRARIAN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Research and Innovation actions
Countries involved: Greece,Germany,Italy,Romania,Ireland,Portugal,Malta,Spain,Switzerland
Call: Open source solutions for edge, cloud and mixed model applications to strengthen production and administrative capacities in agriculture (HORIZON-CL6-2023-GOVERNANCE-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 4997726.25
EU funding (EUR): 4997726.25
Participants: 13
Project status: SIGNED

AGRARIAN will focus on the design of an open and highly dynamic environment (TRL 5-7) with respect to the tools, reuse, composability and orchestration so as to enable tailored open-source digital solutions that will enhance sustainability performance and competitiveness of the agricultural sector. AGRARIAN will leverage mature and sophisticated technologies addressing the requirements of different workloads through a new programming environment and tools for the automated refactoring of existing and/or new applications and data management frameworks enabling them to operate in edge-based deployments as well as new edge-native programming abstractions and middleware. Based on widely accepted open source technologies and adoption of container-based technologies and orchestrators, AGRARIAN platform aims to offer: Smart connectivity for secure access to any of the relevant network infrastructure options; Ability to dynamically meet latency, configuration and other requirements of each of the different network technologies; Integration of edge and cloud for a transparent infrastructure to organize and deploy software components on demand; Uniform management of distributed digital infrastructure for different edge types, cloud components and services; Dynamic deployment and provisioning of services and applications that are time- and location-dependent; Management of data to maintain data security and optimize data processing; Optimisation of operations in terms of energy consumption by enabling new tools and apps for field operations and resource use; The proposed AGRARIAN environment will enable the development of new tools and apps for the agriculture by improving operational effectiveness and efficiency through real- time data processing. A strong ADSS (Agricultural Decision Support System) tool will be developed taking into consideration all specificities of farmers in rural communities enabling end users and stakeholders and maximize their benefit.

Keywords: edge,cloud,iot,satellite,cube sat,programmable framework,dss
European Startup Nations Alliance (ESNA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Cluster 4 other
Destination: Other Digital, Industry and Space destinations
Action type: Coordination and support actions
Countries involved: Portugal
Call: European Startup Nations Standard (HORIZON-CL4-2021-ESNS-IBA, 2021)
Start date: 2022-07-01
End date: 2024-06-30
Duration (months): 24.0
Total project cost (EUR): 1000000.0
EU funding (EUR): 1000000.0
Participants: 1
Project status: CLOSED

The time is now to bring Europe to the forefront of the global startup ecosystem, in order to boost societal health and wealth and increase economic growth, especially in this period of recovery following the COVID-19 global pandemic. The world will not be the same again, and Europe has a fantastic opportunity to become a global leader in the world of tomorrow if it manages to convert its potential as a continent of innovators, pioneers, and entrepreneurs into a competitive, well organized and coordinated ecosystem of startups. For that, Europe must establish the best framework conditions that can help the most promising and strategic startups stay and flourish in Europe and grow to compete globally. The signature of the EU “Startup Nations Standard” declaration in March 2021, as a formal commitment of 27 European countries to enhance these framework conditions through the adoption of best practices, and now the creation of the Europe Startup Nations Alliance (ESNA) as a new Startup Nations’ hub to coordinate, support and monitor national progresses towards this process, are the two key elements of this European policy. The present proposal is focused on establishment of ESNA with the mission to accelerate the growth of European entrepreneurship by improving national policy frameworks of the ESNA Member countries on the common standards agreed upon in the Startup Nations Standard Declaration, and to continuously identify and develop best practices into deployable policies based on analysis of data gathered from members on a digital platform, providing up to date key information of the

Keywords: startup nations standard,startup national ecosystems,scaleups