Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Breath analysis sensor for disease detection in the dairy industry (BREATHSENS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Netherlands
Call: Call for proposals for ERC Proof of Concept Grant (ERC-2020-PoC, 2020)
Start date: 2021-01-01
End date: 2022-06-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Dairy products accounts for some 5% of the global food intake, with dairy industry revenues in 2019 of around €675 billion. This dietary component is important in the global challenge of feeding the increasing human population that is expected to reach 9.7 billion in 2050. To attain peak productivity and efficiency, the health and well-being of each dairy cow is of paramount importance. We aim to use a non-invasive and automated spectroscopic sensor applied on breath, so that illness in individual cows can be detected well before clinical symptoms manifest. The technology is derived from the extremely sensitive and ultra-high spectral resolution cavity-enhanced spectroscopic methods developed in fundamental investigations on molecular hydrogen. We will first target ketosis, which is a common metabolic deficiency that causes estimated losses of more than €1 billion per year for the EU dairy farming industry. The continuous monitoring and early illness detection would enable timely and tailored feed adjustments by farmers to prevent or alleviate disease progression. The goal of this project is to make a portable prototype and explore opportunities of building a sustainable business around it. This novel and unique method will not only help reduce economic costs and minimize environmental emissions, but will help ensure a better quality of life for the farm animals.

Keywords: breath analysis,biomarker detection,pre clinical illness detection,molecular spectroscopy
Hide and Seek with Cancer Drugs (DeShield)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Germany
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-06-01
End date: 2018-11-30
Duration (months): 18.0
Total project cost (EUR): 149981.0
EU funding (EUR): 149981.0
Participants: 1
Project status: CLOSED

Cancer is one of the most prominent causes for morbidity and mortality in industrialized countries. The key challenge in drug-based anti-cancer therapy is to efficiently kill the cancer cells while minimizing side-effects on healthy parts of the body. The DeShield project will establish the proof of concept for a novel approach to upgrade existing anti-cancer drugs in a way that the anti-cancer effect will be increased while side-effects will simultaneously minimized. DeShield technology will be used to shield approved anti-cancer drugs while circulating in the body in order to minimize side effects. Once the shielded drug accumulated at the cancer site, an external stimulus will be applied to trigger de-shielding. The drug will then locally and specifically be taken up by the cancer cells to exert its therapeutic effect. We have successfully demonstrated the functionality of the DeShield technology using the clinically approved anti-cancer drug Doxil and human cancer cell lines: when the shield is intact, the drug is not taken up by the cells, only upon inducible un-shielding the drug enters and kills the cells. In the DeShield project we aim at establishing the Proof-of-Concept that this approach is functional in cancer animal models, that it increases the therapeutic effect while minimizing side-effects. To this aim we have assembled a team with high expertise in complementary areas covering the technology itself, the conductance of preclinical animal studies up to clinical trials as well as business expertise. The technical advance obtained in this project together with a comprehensive market research and the development of a business strategy will shape a highly attractive commercial proposition for the successful valorization of our ERC-funded research.

Keywords: drug delivery,cancer,side effects
Non-Territorial Autonomy as Minority Protection in Europe: An Intellectual and Political History of a Travelling Idea, 1850-2000 (N-T-AUTONOMY)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Austria
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-04-01
End date: 2023-05-31
Duration (months): 62.0
Total project cost (EUR): 1499556.0
EU funding (EUR): 1161556.0
Participants: 2
Project status: CLOSED

Over the past 150 years, non-territorial autonomy has been one of three models for dealing with linguistic or ethnic minorities within several European states. Compared with the other two, i.e. the recognition of minority rights as individual rights and territorial self-rule, non-territorial autonomy has received little attention. This project proposes to write the first history of non-territorial autonomy as an applied policy tool in minority protection and as an intellectual concept with a chequered history across Europe. Intellectuals, politicians, and legal scholars across the political spectrum from the far left to the far right supported this idea, although they were aware of the risks of strengthening national differences by promoting such a collective approach to minority protection. The project explores how this idea of granting cultural rights to a national group as a corporate body within a state, as a means of integrating diverse nationalities, travelled and transformed throughout the Habsburg Empire from 1850 to the present. We propose to 1) trace the development/circulation of theoretical conceptions and political applications of non-territorial autonomy within the Habsburg Empire, by mapping the networks of scholars as well as politicians who advocated for it; 2) explain the continuities in the development of the idea, and its manifestations in policies adopted by interwar Central and Eastern European nation states, where communists, socialists, liberals and fascists alike were able to translate elements of non-territorial autonomy into their ideologies and programs; 3) analyse the treatment of non-territorial autonomy, which was advocated by minority lobby groups, in international minority protection in the 20th century despite strong opposition to practices based on it by international organisations. We rely on a mixture of historiographical methods developed in nationalism studies to analyse the idea’s translation in entangled transnational spaces.

Keywords: minority protection,habsburg empire,central and eastern europe,interwar europe,international minority rights,intellectual history,nationalism studies
Next-Generation Computational Methods for Enhanced Multiphase Flow Processes (COMETE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Industrial Doctorates
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Austria,Italy,Italy,Poland,Belgium,France
Call: Innovative Training Networks (H2020-MSCA-ITN-2018, 2018)
Start date: 2018-11-01
End date: 2023-04-30
Duration (months): 54.0
Total project cost (EUR): 753185.52
EU funding (EUR): 753185.52
Participants: 6
Project status: SIGNED

In this project, we aim at building a computational framework and a network of competence to extend the applicability of state-of-the-art formulations to industrially-relevant multiphase turbulent flows. We focus on applications characterized by the transport of particles/droplets in two-phase flows with gas-liquid or liquid-liquid deformable interfaces, which are ubiquitous in process, chemical, and power engineering. The targeted applications are at the crossroads between academic research and practical concerns (e.g. particle deposition in boiling flows, droplet coalescence/breakup in emulsions, freezing/defreezing in heat pipes or changes in two-phase flow patterns) and their modeling in an industrial context represents a major challenge. This is due to the complexity arising from the co-existence of different phases, but also to a lack of cross-fertilization between academia and industry: Several methods and ideas exist but their application is often limited to flows of academic interest, with scarce transfer of skills, poor experimental validation and, most importantly, no unified framework into which existing methods could be cast. This represents a serious obstacle to industrial developments since engineers and practitioners can be unaware of which method to use and in need of support. To build the new framework, we consider emerging complementary methods, including Smoothed Particle Hydrodynamics and Phase Field. COMETE leverages on the complementary expertise of the industrial and academic partners to ensure successful combination of technology-driven objectives and original research developments. To this aim, we will build an international network of excellence by putting forward synchronized training-through-research and training-on-the-job activities, and we will form PhD students fully capable of mastering the next-generation scientific methodologies for complex industrial applications of multiphase flow technology.

Keywords: multiphase flow,multiscale modeling,process engineering,training through science,training on the job
uncovering the anatomical archive of annual RINGS to understand abiotic and biotic drivers of SHRUB growth at the range BORDER (BoRiS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-01
End date: 2022-09-30
Duration (months): 24.0
Total project cost (EUR): 207312.0
EU funding (EUR): 207312.0
Participants: 1
Project status: CLOSED

Climate change is observed and predicted to profoundly affect Arctic and Alpine ecosystems. These ecosystems, at the border of woody plant growth, change at a faster rate than the global average. Growth responses of Arctic-Alpine shrubs to climate change are variable and influenced by different factors. A key to understand the plasticity of responses to climate change is a detailed analysis of growth at the intra-individual to the community level. Currently, we lack knowledge on the intra-individual, intraspecific, and interspecific variation in growth and wood anatomical traits across environmental gradients. BoRiS aims at uncovering the information archived in annual rings to gain fundamental new insight on how the responses scale from individuals to communities. Insight into past dynamics opens a valuable window to the future and provides the basis for predicting future range dynamics of Arctic-Alpine shrubs. BoRiS provides a retrospective quantification of growth and wood anatomical traits from Arctic-Alpine shrub species, assesses their variation across environmental conditions, tests their significance as climatological proxies, disentangles the abiotic and biotic factors influencing growth, and models future shrub dynamics at the landscape to regional scale. BoRiS is possible due to a unique data set of > 1000 individual shrubs sampled in Arctic and Alpine areas and an innovative integration of state-of-the art quantitative wood anatomical analyses, classical dendrochronology, a newly proposed community-based dendroecology framework, range dynamic modelling and remote sensing observations. It is the first project to combine growth and wood anatomical responses of a large number of Arctic-Alpine shrubs and to upscale the results from individuals to communities. BoRiS is envisioned to be the first step in the development of an independent research field linking plant growth dynamics in a community perspective with earth observations across space.

Keywords: arctic and alpine shrubs,climate,chronology,quantitative wood anatomy,range distribution,xylem
Crisis Communication and Deterrence: The Interaction of Facts and Fictions (CODE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-08-01
End date: 2025-07-30
Duration (months): 24.0
Total project cost (EUR): 219312.0
EU funding (EUR): 219312.0
Participants: 1
Project status: SIGNED

This media-historical project examines crisis communication from the Cold War up to the subsequent War on Terror and beyond. The goal is to investigate how the interaction of the factual and fictitious crisis communication triggered fear and deterrence concepts--and vice versa. Media studies lack an analysis of how media participate in a political actor network. The proposed project is the first contribution that examines the chain of operations in politics in detail and discusses how media become political. First, the researcher seeks to show how both factual and fictitious channels of communication characterize the Cold War as a conflict that is not only determined by actual events and political concepts, but also by fictions of nuclear war. The mutual analysis of the fictitious Red Telephone and of the existing hotline between Washington and Moscow should unfold the interwoven history of Cold War crisis communication. It is proposed that both facts and fictions affect deterrence concepts and fear. Second, the researcher examines the ambivalent function of third parties who intervened in the bipolar structured channel between the USA and the USSR. The objective is to show that disruptive third parties provoke societal self-reflections: While British and French hotlines to the USSR paradoxically strengthened the USA-USSR-channel, fictitious actors such as computers questioned rational actors within the military chain of command and excluded human actors to secure peace or trigger a nuclear war. Third, the researcher investigates the media break after the Cold War and the simultaneous emergence of networked crisis communication and the War on Terror. In fiction, the networked hotline must protect itself from attacks by hackers. In real life, digital diplomacy emerges along with the establishment of new media, such as Twitter. The inherent danger of social media (e.g.,Tweets from D.Trump) is that they could constitute a hyperreality that loses connections to reality.

Keywords: media theory,cultural techniques,discourse analysis,actor network theory,popular cultures
From Digital to Distant Diplomatics (DiDip)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The study of the human past
Panel description: Archaeology, history and memory
Countries involved: Austria
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2022-01-01
End date: 2026-12-31
Duration (months): 60.0
Total project cost (EUR): 2812500.0
EU funding (EUR): 2812500.0
Participants: 1
Project status: SIGNED

From Digital to Distant Diplomatics (DiDip) will bring modern computational methods to the transregional study of late medieval charters. It will answer questions about the spread and development of pan-European documentary practices and documentary culture in the later medieval period (c. 1300-1500). The project's novelty lies in 1. the scale of the endeavour, building upon a database of over half a million digitized charters from medieval and early modern Europe (the PI's Monasterium.net) and expanding it both numerically and qualitatively and 2. the application of cutting-edge ‘distant’ macroanalysis practices (Jockers 2013) to a Europe-wide dataset, producing findings that go beyond the traditional regional and single-institution related scope of diplomatics projects. At the core of this project is the observation that the preponderance of studies in diplomatics have been and remain focused on smaller units, such as individual chanceries, collections of single institutions, or the practices of one country, language group or region (Jarret 2013) and the resignation of diplomatics scholars in the face of the large amount of documentation in the 14th and 15th century. How can we truly make an integrated study of European diplomatics in this period when it is largely addressed as a variety of hyperlocalized phenomena, without meaningful study of the relation of the practices of one area to another? The DiDip project answers this question by building a digital research environment to study the issue on a macro scale, improving the quality of research data and the methods available to enable greater breadth of study and provide findings that will point us towards a better understanding of the relationship of the various regional documentary cultures across Europe in the period.

Keywords: diplomatics,later middle ages,virtual research environment,macroanalysis,distant reading,europe
Bringing Earth Observation Services for Monitoring Dynamic Forest Disturbances to the Users EOMonDis (EOMonDis)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: Innovation actions
Countries involved: Austria,Germany,France,France
Call: Bringing EO applications to the market (H2020-EO-2015, 2015)
Start date: 2016-02-01
End date: 2019-07-31
Duration (months): 42.0
Total project cost (EUR): 2528139.75
EU funding (EUR): 1969106.0
Participants: 5
Project status: CLOSED

The EOMonDis Project aims to improve the operationality of tropical forest products/services in order to better access the funding for the UNFCCC REDD+ policy which is a large market segment for the EO-industry in Europe. Additionally, national forest policy programmes and Zero Deforestation programmes also require forest monitoring systems with assessment of forest/non-forest information using disturbance indicators for deforestation and degradation as well as changes in above ground woody biomass. In order to provide operational forest monitoring services for the humid and dry forests several technical challenges have to be overcome. For example, the occurrence of persistent cloud conditions in tropical regions impact the effective use of optical EO data. Seasonal effects in dry forest ecosystems (leaf-fall) combined with limited availability of multi-seasonal EO data coverages also influence the quality and cost effectiveness of the monitoring systems. These situations will change drastically with the Sentinel constellations which provide the high frequency, high resolution optical and radar data required. Therefore, the overarching goal of EOMonDis is to develop innovative and cost-effective EO-based methods to address the technical challenges for tropical forest monitoring which will also fully utilize the comprehensive information provided by the dense time series of optical and SAR satellite data of Sentinel-1 and 2. The methods developed will be tested on study sites selected to represent the wide range of variety in the tropical biomes, in Malawi, Cameroon, Gabon and Vietnam. Users from these countries will be consulted for consolidation of the service requirements, validation of the services, the customization and improvement of the services to fit into their workflows. Based on a market analysis and service validation by the User a 3year business concept will be developed to ensure that there is income generation after the project completion.

Keywords: redd market,monitoring tropical forests,dense time series,sentinel 1 and 2 data,near real time service,commercial service platform
Conservation genomics of endangered indigenous European horse breeds (ENDANGEREDHORSES)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-03-15
End date: 2019-03-14
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

The European continent encompasses about half the total number of horse breeds on the planet. According to the Food and Agriculture Organization of the United Nations, about a quarter of those breeds are currently endangered as they have been disused since the mechanization of farming and transportation, and have suffered massive losses during the first and second World Wars. These breeds were developed over long historical periods, in a variety of ecological and socio-cultural contexts. As such, they represent an invaluable component of our common genetic and cultural heritage and the living incarnation of European terroirs. Our proposal aims at undertaking the first genetic monitoring of ~120 endangered and autochthonous European breeds at a genome-wide level. Our extensive genetic dataset will enable a precise reconstruction of the horse breeding history in Europe, revealing the long-debated origins of iconic breeds and the genetic impact of different management strategies and environments. Additionally, it will open for an identification of breed-specific Ancestry Informative Markers and an estimation of key genetic parameters and population structure, allowing the development of informed conservation guidelines, aimed at maximizing the genetic potential of endangered breeds and minimizing mixing between breeds of unrelated history. Importantly, ENDANGEREDHORSES will showcase the potential of genome-wide approaches in helping preserve the genetic diversity of livestock resources, which is currently of concern for horses and all other domestic animals worldwide.