Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Grass Fibre as raw material for innovative Grass Paper products: the new economic and ecological resource for the European paper industry (Grass Paper)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2018)
Start date: 2018-10-01
End date: 2020-11-30
Duration (months): 26.0
Total project cost (EUR): 2757500.0
EU funding (EUR): 1930250.0
Participants: 1
Project status: CLOSED

With GRASPAP Grass Fibre Creapaper introduces a highly innovative, sustainable and cost-efficient alternative raw material for the European paper industry. About half of the 400 million tonnes paper produced worldwide every year are based on wood pulp. This consumes about 40% of the global industrial wood harvest. Moreover, transport and processing of the wood consume a lot of water, chemicals and energy. Costs and impact to nature are severe. Creapaper provides an unique solution to this problems by introducing Grass Fibres, produced by a novel patented mechanical process, as a new resource for the paper industry. This innovative material will reduce the raw material costs of paper mills by 50-70 % (compared to wood pulp) and is compatible to their standard production equipment. Grass Paper products made from these fibres are free of noxious substances, printable and have a distinctive sustainable, yet premium appearance. They are therefore very attractive for food and non-food packaging, tissue and print media applications. Several awards in the packaging industry and first orders from large, well-known brands confirm these USPs of Grass Paper products. While Creapaper's primary customers are paper mills, also brand owners and retailers will be addressed. This will increase the demand for Grass Paper and Grass Fibres rapidly and allow a fast scale-up in the European key markets. According to independent experts, the grass fibre material has the potential to become the paper industry's third raw material source besides wood pulp and waste-paper. Creapaper currently installs the first grass fibre production line and will transfer the stationary production process into a versatile mobile solution during this project. This will decrease the dependence on weather conditions during the grass harvesting as well as allow the extraction and commercialisation of vegan proteins from the grass in the future, making the whole process even more sustainable and cost-efficient.

Keywords: grass,grass paper,grass fibre,alternative fibre source,virgin fibre,pulp,non wood paper,eco friendly,forest,protection,paper revolution,packaging
Dragon - Sustaining Technology And Research Plus (EU-China Collaboration) (DRAGON-STAR Plus)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Coordination and support actions
Countries involved: Germany,Austria,Italy,China,Sweden,Switzerland,Greece,Greece,France,Portugal
Call: Enhancing and focusing research and innovation cooperation with the Union’s key international partner countries - proposals targeting Russia and China (H2020-INT-INCO-2014, 2014)
Start date: 2015-02-01
End date: 2018-01-31
Duration (months): 36.0
Total project cost (EUR): 2227812.5
EU funding (EUR): 1949999.5
Participants: 16
Project status: CLOSED

China is already an important global actor in the fields of research and innovation, and has the potential of becoming a leading force in the next few decades. The shift in China’s strategy focusing towards R&I and transforming the essence of its economy has been complimented with massive public investments in research and technology. The EU having recognised the leading role China is expected to play, and having adopted a strategic position for becoming a knowledge-based economy, is required to collaborate with China in areas of mutual interest, and for common benefit and prosperity. Moreover for critical global issues which demand close scientific and technological cooperation at an international level, EU has identified in China a natural partner able to contribute and complement its own capacity. The proposed initiative aims to provide support services to European and Chinese researchers, and a flexible platform to facilitate policy discussions between European and Chinese stakeholders. Moreover, DRAGON-STARPLUS will provide the EC and the Member States with a toolset for setting a long term cooperation strategy in research and innovation with China. The project aims to provide efficient services on three levels (priority areas): - Support the European and Chinese research communities to establish collaborations under Horizon 2020 and beyond. -Provide a cooperation platform and tools to policy makers, aiming ultimately to support and enhance the bilateral cooperation, through the concept of mutual benefit. -Provide an ERA-NET style platform to funding agencies for exchanging best practices and planning joint activities. The proposed activities take into account the current on-going policy dialogue and the peculiarities of the research and innovation environment in China, and are based upon the outputs and the established mechanisms of the previous DRAGON-STAR project, as well as upon the sound results of previous related projects (e.g. OPEN-ICT, CO-REACH).

Keywords: china,research,innovation,policy,foresight,future scenarios,reciprocity
Nanoscale Digital Microscope (NanoXim)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Novel ideas for radically new technologies
Action type: Coordination and support actions
Countries involved: France
Call: FET Innovation Launchpad (H2020-FETOPEN-2018-2019-2020-03, 2019)
Start date: 2020-11-01
End date: 2022-04-30
Duration (months): 18.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 2
Project status: CLOSED

The NanoXim project proposes a disruptive nanoscale holographic microscope with a sensing architecture that can compensate for the lack of complexity of usual optical components (confocal) or markers (fluorescent) by use of novel theories and numerical algorithms. The technique based on digital holography allows to realize 3D movies with sub-µm resolution. The instrument developed CEA builds phase contrast maps of a specimen by using 3D propagation and numerical reconstruction algorithms already implemented in a user-friendly interface. We propose realize a study of the a large panel of end-users and also to validate immediate needs and requirements in health problems and bio-technology. First objective consists in supporting CEA to bridge the gap from research prototypes to the pre-commercial products and initiate the creation of a start-up. We will increase of the technology readiness of the instrument. TEMATYS SME will support this by bringing a market analysis and set a full business model. We will seek for valorization through patenting and licensing to put the instrument close to the market. A startup creation willbe initiated.

Keywords: holography microscopy single cell
Revolutionizing Insect Control (REVOLINC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Italy,France,France,France
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2016-09-01
End date: 2021-08-31
Duration (months): 60.0
Total project cost (EUR): 1993281.0
EU funding (EUR): 1355109.75
Participants: 4
Project status: CLOSED

EFSA recently prohibited 75% of insecticides to account for their toxicity and ecotoxicity. Moreover, the spread of insecticide resistance and invasion of Europe by new tropical vectors and pests require the development of alternative biological techniques. Recently, we hypothesized that shifting the vision of the sterile male from a sexual competitor only to a specific transporter of active biocides to the targeted female might boost the impact of the sterile insect technique (SIT). Here we want to demonstrate this concept using three biocides: Pyriproxifen, Bacillus thuringiensis and a Densovirus against the Tiger mosquito (Aedes albopictus). Pyriproxifen will also be tested against tsetse and fruit flies. We will test the technology both in the laboratory and at an operational scale and model the relative impacts of SIT and boosted-SIT on the dynamics of the targeted population. Moreover, we will compare the evolutionary response of the target population to these different control pressures (multiple lethal mutations, multiple lethal mutations + biocides), for three different biocides and three demographic strategies. This will generate breakthrough knowledge on the transmission of biocides and pathogens in insects and the sustainability of genetic control, provide a new control technique for mosquitoes, and improve the cost-effectiveness of SIT in tsetse and fruit flies. We will have to address technical issues associated to mass rearing, sterilization, sex separation and aerial release of mosquitoes as well as regulatory issues required for releasing sterile males coated with bioicides.

Keywords: sterile insect technique,pyriproxifen,tiger mosquito,medflies,tsetse,ridl,densovirus,bacillus thuringiensis var israelensis
Demonstration project to prove the techno-economic feasibility of using algae to treat saline wastewater from the food industry. (SALTGAE)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Theme: Enabling the transition towards a green economy and society through eco-innovation
Action type: Innovation actions
Countries involved: Italy,Ireland,Spain,Spain,Italy,Israel,Italy,Italy,Italy,Spain,Belgium,Slovenia,Sweden,Sweden,France,Portugal
Call: Demonstration/pilot activities (H2020-WATER-2015-two-stage, 2015)
Start date: 2016-06-01
End date: 2019-09-30
Duration (months): 40.0
Total project cost (EUR): 9844741.39
EU funding (EUR): 8294318.87
Participants: 25
Project status: CLOSED

The aim of the project is to implement and demonstrate at large scale the long-term technological and economic feasibility of an innovative, sustainable and efficient solution for the treatment of high salinity wastewater from the F&D industry. Conventional wastewater treatments have proven ineffective for this kind of wastewater, as the bacterial processes typically used for the elimination of organic matter and nutrients are inhibited under high salinity contents. Therefore, generally combinations of biological and physicochemical methods are used which greatly increase the costs of the treatment, making it unaffordable for SMEs, who voluntarily decide not to comply with EU directives and discharge without prior treatment, causing severe damage to the environment. The solution of SALTGAE to this issue consists in the implementation of innovative technologies for each step of the wastewater treatment that will promote energy and resource efficiency, and reduce costs. Amongst these, the use of halotolerant algae/bacteria consortiums in HRAPs for the elimination of organic matter and nutrients stands out for its high added value: not only will it provide an effective and ecological solution for wastewater treatment, but also it will represent an innovative way of producing algal biomass, that will subsequently be valorized into different by-products, reducing the economic and environmental impact of the treatment. Moreover, the project will also address cross-cutting barriers to innovation related to wastewater by developing a platform for the mobilization and networking of stakeholders from all the different sectors related to wastewater, and for the dissemination of results, enabling the development of a common roadmap for the alignment of legislation, regulation and pricing methodologies and promoting financial investment and paradigm shift in perception from ‘wastewater treatment’ to ‘resource valorisation’.

Keywords: wastewater,saline,algae,bacteria
Unravelling the moral self (MORALSELF)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Human Mind and Its Complexity
Panel description: Cognitive science, psychology, linguistics, theoretical philosophy
Countries involved: Germany
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-09-01
End date: 2022-02-28
Duration (months): 66.0
Total project cost (EUR): 1498958.0
EU funding (EUR): 1498958.0
Participants: 1
Project status: CLOSED

Philosophers and social scientists have emphasized that our moral self-concept, the degree to which being moral is central for us, plays a pivotal role in explaining humans’ tendency to act prosocially. Clarifying the development of the moral self-concept and discovering the functional mechanisms is thus central for clarifying the basis of human morality. Despite a set of perennial questions that the moral self-concept relates to and the empirically proven relevance, research has largely neglected the early ontogeny of the moral self-concept. This is all the more surprising as recent developmental research demonstrated a hitherto unknown inclination of young children to act prosocially, which has led to a theoretical reorientation in developmental science. Moreover, the neurocognitive basis of moral identity as well as the functional mechanisms that relate moral identity to prosocial behaviour have have yet to be discovered, leaving the ontogeny and the nature of the moral self-concept in the dark. In this proposal I will take a new approach by combining novel tools derived from developmental psychology and cognitive neuroscience to provide a comprehensive model of the moral self-concept that integrates (i) knowledge on the developmental origins and changes, (ii) its neurocognitive basis, and (iii) the functional mechanisms that relate the moral self-concept to actual prosocial behavior. To this end, the project relies on an interdisciplinary methodological approach by combining explicit interview measures, implicit attitudes tests, behavioral assessments, and electrophysiological methods with both children and adults to empirically explore the human moral self-concept. The current project not only contributes to a perennial debate on the origins of human morality; providing knowledge on the factors that promote the moral self-concept will also have societal impact by informing theory and practice of moral education.

Keywords: development,preschool children,morality,prosocial behavior,self concept
Integration of Heat flux sensor in (wrist) wearable devices for accurately and non-invasively continuous monitoring of core body temperature (CBT) for the early detection of health-related disorders (gSKIN BodyTemp)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Switzerland
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Wearable biosensor systems for fitness and health monitoring have become popular in the last years, however, there is no wearable technology available for accurately monitor core body temperature (CBT) to date. In consequence, gSKIN BodyTemp (gSKIN BT hereafter) project aims at providing the first thermal sensor for non-invasive, wireless and continuous CBT monitoring; also meeting size requirements to be integrated in wrist wearable devices. The invention relies on our patented heat flux technology, a cost-effective thermal sensor plus sophisticated machine learning algorithms allowing accurate (±0.2°C) and real-time CBT measurements for the first time on the wrist and under free living conditions. gSKIN BT will result on added value for high-quality wearables, improving healthcare and sport medicine by enabling ubiquitous CBT monitoring. Other valuable novelties are its reduced cost and lower energy consumption compared to the available options. These advantages make gSKIN BT a disruptive solution with great potential for commercial success in the growing wearables market (€123 B by 2026, CAGR 35%), representing a core source of growth for the company and consolidating our position in the thermal sensing sector. We will conduct a feasibility study and a business plan analyzing the technical, commercial and financial aspects required to ensure the market launch. Being CBT an important vital parameter involved in some of the biggest health issues (e.g. sleep disorders, Parkinson and Alzheimer diseases), gSKIN BT will be a great enabler for the necessary transformation towards a patient centred preventive health care system.

Keywords: core body temperature,heat flux sensor,wearable devices,wireless health monitoring
Flowbase (Base)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Germany
Call: European SME innovation Associate - pilot (H2020-INNOSUP-2019-02, 2019)
Start date: 2019-09-01
End date: 2020-10-31
Duration (months): 14.0
Total project cost (EUR): 120625.0
EU funding (EUR): 120625.0
Participants: 1
Project status: CLOSED

Miraminds currently offers software which enables IT-divisions of SMEs to automatically capture and store workflows for their colleagues. The next step is to develop a solution for this final and most challenging problem: automatically displaying the right workflow upon need of the user, without the user searching for it himself. Solutions that are similar to miraminds are only affordable for medium and large size companies. They have a long implementation period and require a great effort of all employees involved. The objective of the recruitment of the innovation associate is developing a technology that replaces the cumbersome manual loading of files from a local file system with an intelligent (AI-based) cloud solution (named Flowbase) that allows for: - Automated and seamless storing/loading of workflow data on a server/cloud from within our desktop software product. - Intelligent search and/or recommendation of workflows based on a user’s work context. By offering this new solution (Flowbase) we are planning to transform miraminds from a pure software vendor toward a data/platform/AI company. We offer the opportunity to introduce machine learning expertise into a new area of application which will possibly come with unique challenges and thus, lead to unique research results. To task of the associate will be to utilize predictive analysis with an approach that in the literature is known as collaborative filtering. The intelligent platform Flowbase would offer IT departments in SMEs an affordable and easy to use solution to automate and individualize their first level IT support.

Keywords: developing a technology that replaces the cumbersome manual loading of files from a local file system with an intelligent ai based cloud solution
Unmasking cellular and molecular networks encoding risk and resilience in Alzheimer’s disease (AD_AGING_AND_GENDER)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing, nervous system function and dysfunction, systems neuroscience and modelling, biological basis of cognitive processes and of behaviour, neurological and mental disorders
Countries involved: Israel
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-06-01
End date: 2025-05-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

AlzheimerAlzheimer’s disease (AD) is a crucial problem in our society, raising the need for new therapeutic targets. Evidence suggests multiple non-neuronal cells are implicated in the systemic deficits of AD, but the complex cellular diversity in the brain hampers the investigation of specific cells and their interactions. Moreover, the course of the disease is highly variable, due to multiple risk factors, including aging and gender, which have overlapping molecular signatures with AD that might be further masking disease mechanisms. I propose to expand the resolution from tissues to cellular environments, and to untangle overlapping molecular signatures of gender and aging, in order to unmask molecular mechanism of AD. Technological advances in genomics and imaging, including the single nucleus RNA-sequencing methods developed by me, as well as my expertise in computational analysis and CRIPSR perturbations, provide a unique opportunity to address this challenge. I obtained preliminary results strongly suggesting that multiple cell types are indeed altered in AD brains of mice and humans, and that gender, aging, and AD have overlapping molecular features. I hypothesize that age-dependent cellular/molecular alterations are key drivers of cognitive decline, and that the dynamics of these alterations determine risk and resilience levels in individuals. We will test this hypothesis by: 1) Charting the cellular microenvironments and tissue topology of the human AD brain, to reveal cells, pathways, and cellular interactions driving AD; 2) Mapping the dynamic cellular/molecular trajectories in aging and AD in w.t. and AD mice, to untangle AD, aging, and gender dimorphism; and 3) Identifying regulators of cognitive resilience and decline in AD and aging, and connecting genes to function by detailed mechanistic investigations in vivo. Overall, our innovative proposal is expected to advance our understanding of AD mechanism, and the link to aging and gender dimorphism.