Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Wireless Power for Autonomous Sensor Systems (WiPASS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-04-01
End date: 2021-03-31
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: CLOSED

Internet of Things (IoT) is a booming market that will impact our daily life with the deployment of billions of electronic devices. Digitalization is therefore a priority of the EU policy. Massive adoption of IoT requires energy autonomy and wireless devices. Powering such devices remains a challenge that WiPASS wants to tackle. WiPASS project is aimed at developing an innovative and disruptive Wireless Power Transfer (WPT) technology exploiting a low-frequency variable magnetic field to send electric power over the air between an emitter and receivers based on an electromechanical system. This power is then used to supply electronic functions such as sensors and actuators. Compared to other WPT technologies, the one proposed in WiPASS operates at lower frequencies enabling to reach higher transmission distances with better penetration in conductive media. Proofs of concept of this technology have been developed by The Researcher, Nicolas Garraud, during his PhD thesis in the University of Florida. The Researcher now wants to further develop and optimize this technology, to solve the limitations and to study its commercial relevance once integrated in an electronic system. The Researcher will carry out this research in CEA-LETI (France), renowned in Energy Harvesting and Wireless Power Transfer technologies, under the supervision of Sebastien Boisseau, Energy Harvesting Expert. WiPASS project will be a springboard toward a Research Team Leader position in 5 to 7 years in a European public or private actor for The Researcher. WiPASS will boost the career of The Researcher thanks to the new skills he will acquire, an improved visibility, a higher maturity in communication, project writing and management, and exchanges with academic and private partners of CEA-LETI. It will also boost IoT deployment in Europe by solving the issue of the energy autonomy of wireless devices, paving the way to new breakthrough in Health, Smart Cities, Transport and Industry.
Bioinorganic intracellular synthesis of photo-responsive bio-camouflaged nanomedicines (NanoBioMade)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physical and analytical chemical sciences
Panel description: Analytical chemistry, chemical theory, physical chemistry/chemical physics
Countries involved: France
Call: ERC Consolidator Grant (ERC-2019-COG, 2019)
Start date: 2021-02-01
End date: 2026-01-31
Duration (months): 60.0
Total project cost (EUR): 1967000.0
EU funding (EUR): 1967000.0
Participants: 1
Project status: SIGNED

Exposed to smart man-engineered nanomedicines, cells can profoundly transform and recycle them. To communicate, or in response to exogenous stress, cells generate extracellular vesicles which can play crucial roles in multiple physiological processes, as for instance, and unfortunately, for cancer progression. The goal of this proposal is to combine both biological events to deliver nanomedicines created by cells only, using mesenchymal stem cells as the most relevant cell model. The focus of this proposal on nano-bio-production is three-fold. - In the first instance, I aim to rationally develop novel strategies for bioinorganic intracellular synthesis of nanoparticles. The first aspect will be to demonstrate, as suggested by preliminary data, that nanoparticles degradation products can be de novo-synthesized nanoparticles! And also that nanoparticulate end products can also be obtained when cells are “fed” with soluble ionic salts. The vicarious synthesis using living cells as bioreactors, will allow creating functional, sophisticated and organism-friendly nanoparticles. Basic ingredients and little chemical proceedings should lead to advanced prospectively biological nano-tools. When iron and cobalt constituents will be used as precursors, cells will generate nanoparticles with magnetic and photothermal properties. - The second focus is devoted to nanoparticles biological encapsulation. Indeed, in order to be useful, nanoparticles should be efficiently delivered to the target site. In the strategy to make “100% Bio Made nanomedicines”, it is obvious there are no better delivery systems than the cell’s innate delivery systems, the extracellular vesicles, an especially the ones derived from stem cells, supposed to inherit from their natural tumour homing. Here, ground-breaking physically-inspired (hydrodynamic, light) approaches for production and loading of these vesicles with nanoparticles will be proposed and fully implemented. One specific aim wi

Keywords: magnetic nanoparticles,copper nanoparticles,bioinorganic synthesis,biomineralization,extracellular vesicles,mesenchymal stem cells,drug delivery systems,photothermal therapy,magnetic targeting
Ocean Interaction with Antarctic Ice Shelves (OceanIS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-05-01
End date: 2019-01-01
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The primary goal OceanIS is to constrain the contribution of changes in Southern Ocean circulation to the recent acceleration in Antarctic Ice Sheet mass loss. Improving our knowledge of ice shelf–ocean interactions is a critical step toward reducing uncertainty in future sea level rise projections. Ice shelves are coastal areas of floating ice that extend from an ice sheet out over the ocean, and their destabilization can trigger rapid ice discharge. It is now evident that ocean–driven basal melt is the major cause of ice loss from Antarctica’s fringing ice shelves. However much of the fundamental dynamics of how the ocean delivers heat to the ice shelves remains unresolved. Progress in this area requires bringing together the fields of ice shelf–ocean interactions and large–scale Southern Ocean oceanography. The Southern Ocean overturning entails the upwelling of Circumpolar Deep Water (CDW) offshore Antarctica. The Antarctic Circumpolar Current has shifted poleward, the impact of which, e.g. over the upwelling of CDW, remains unknown. Since CDW is linked to the highest ice shelf thinning rates yet observed, the variability of the CDW properties and its interaction with the ice shelves is the focus of this proposal. To do this, OceanIS integrates, for the first time, several unique data sets, which extend from the deep ocean to the sub–ice shelf environment. These include data from the Argo network, instrumented seals, and measurements from the only decadal–scale record of ocean properties beneath an Antarctic ice shelf, the Amery ice shelf. OceanIS will help to test which of the suite of current climate models shows ice–ocean interaction processes and CDW variability that are most in line with reality. Given that the forcings driving Southern Ocean changes are expected to continue in the future, results of OceanIS will be a major step toward reducing the uncertainty that surrounds the future stability of the Antarctic Ice Sheet and sea level rise projections.

Keywords: southern ocean,cryosphere,antarctic ice shelves,circumpolar deep water,sea level rise
Transcriptional and epigenetic control of innate-like T lymphocyte development (EpiNKT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Greece
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-08-31
End date: 2017-08-30
Duration (months): 24.0
Total project cost (EUR): 164653.2
EU funding (EUR): 164653.2
Participants: 1
Project status: CLOSED

Invariant Natural Killer T (iNKT) cells are a heterogeneous T lymphocyte population that possess innate-like characteristics and contribute to host defense against pathogens. Due to their powerful effector properties, iNKT cells are targeted for immunotherapeutic and vaccination strategies. Their effector programs are acquired during thymic development, prior to microbial exposure, and are polarized into three distinct populations, similar to CD4 Th1, Th2 and Th17 lineages. Specification and subsequent polarization of the NKT lineage is regulated by the balance between the E protein family of transcription factors (TF) and their inhibitors, the ID proteins, which is pivotal in the bifurcation of adaptive and innate lymphoid lineages and is associated with human lymphomas. This application aims at defining the mechanisms by which the E/ID ratio enables the effector properties of innate-like T cells. We hypothesize that the E/ID pathway directly or indirectly regulates critical TFs and chromatin regulators that separately or in combination activate different arms of this effector program. This hypothesis will be tested through the following specific aims: 1) Determine target genes bound by E proteins, 2) Determine the epigenetic chromatin states and 3) Determine the role of chromatin modifiers in developing iNKT cells. While each aim can be accomplished independently, the data will be integrated to form gene regulatory networks that control the innate-like effector programs. The proposal is innovative because it explores the novel idea that the activity thresholds of a single TF dictate distinct cellular fates, while enhancing our understanding on lymphocyte effector programs and link specific chromatin regulators to these programs. The fellowship is rewarding, because the Applicant will gain knowledge in the implementation of high-throughput technologies to study the interplay between TFs-chromatin regulators-chromatin architecture in lymphocyte differentiation.

Keywords: innate lymphocytes,id proteins,development,transcription factors,epigenetics
A minituarized disposable molecular diagnostics platform for combatting coronavirus infections (DECISION)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Public-private partnerships
Destination: Innovative Medicines Initiative 2
Action type: Research and Innovation actions
Partnership: IMI2 (Art-187)
Countries involved: Germany,Italy,Germany,Spain,Austria
Call: Development of therapeutics and diagnostics combatting coronavirus infections (H2020-JTI-IMI2-2020-21-single-stage, 2020)
Start date: 2020-07-01
End date: 2024-06-30
Duration (months): 48.0
Total project cost (EUR): 3747600.0
EU funding (EUR): 3435100.0
Participants: 5
Project status: SIGNED

The DECISION consortium is developing a new class of diagnostic platform that will transform the fight against pandemics. The low-cost, miniaturised, disposable molecular diagnostic platform will allow for patient testing virtually anywhere, within a few minutes, with laboratory quality performance. The diagnostic platform will enable rapid detection of Covid-19 infections on-site in a multitude of settings including drive-through testing centres, physician offices, airports, hospitals and quarantine centres. First demonstrators of the disposable molecular diagnostic platform and coronavirus test will be available five months after the start of the project and could be provided to emergency first responders and public health authorities. The platform is powered by a next-generation nucleic acid amplification technology called Pulse Controlled Amplification (PCA®), which enables sample-to-answer workflows in 15 minutes or less. The DECISION consortium is comprised of teams from Italy, Spain and Germany, and is highly motivated to develop a ground-breaking diagnostic solution to help the serious crisis faced across the world due to the Covid-19 epidemic.

Keywords: molecular platform,onsite,point of care,ultrafast,first responder,home test,rapid detection,molecular testing,handheld,portable,battery powered
Safety in Smart Vehicle - Pedestrian Interaction (SSVPI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-04-01
End date: 2024-03-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

There has been a lot of research on smart vehicles (SV, including autonomous vehicles and smart powered wheelchairs), mainly for motorways and other structured environments, with resulting safety levels in such highly structured conditions being excellent. However, the situation is different for less structured environments, particularly where interaction between SV and pedestrians is possible, such as pedestrian junctions and mixed traffic environments. In these cases, more fundamental research in safety aspects is needed, since even minor contact between humans and vehicle poses serious dangers to unprotected humans. Specifically, pedestrian intention prediction is crucial for safe and smooth SV operation. This project aims to develop multi-source and multi-modal algorithms which can predict intentions of pedestrians under challenging lighting conditions (using both visible (RGB) and thermal imaging), using cues from both pedestrian movements as well as their environmental and social context. The project aims at enhancing the safety level of pedestrians in the context of SV in unstructured environments. Apart from the development of novel algorithms in this challenging domain, we aim to maximise the impact of our research through the creation of one of the first pedestrian intention prediction datasets combining RGB and thermal images. Performance evaluation of intention pedestrian algorithms will involve both vehicles in intersections, as well as smart wheelchairs for people with disabilities. By enhancing the safety level of SV and pedestrians through predicting pedestrians' intention under various lighting conditions, the results of this project will be very helpful for the development of SV, and will also promote the public' s acceptance of SV. Consequently, the results of this project are very beneficial for the EU, where multiple governmental and commercial autonomous driving initiatives are active.

Keywords: pedestrian intention prediction,human vehicle interaction,pedestrian trajectory prediction,autonomous driving,autonomous vehicle,smart vehicle
The Computational Database for Real World Awareness (CompDB)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Computer science and informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-06-01
End date: 2022-05-31
Duration (months): 60.0
Total project cost (EUR): 1918750.0
EU funding (EUR): 1918750.0
Participants: 1
Project status: CLOSED

Two major hardware trends have a significant impact on the architecture of database management systems (DBMSs): First, main memory sizes continue to grow significantly. Machines with 1TB of main memory and more are readily available at a relatively low price. Second, the number of cores in a system continues to grow, from currently 64 and more to hundreds in the near future. This trend offers radically new opportunities for both business and science. It promises to allow for information-at-your-fingertips, i.e., large volumes of data can be analyzed and deeply explored online, in parallel to regular transaction processing. Currently, deep data exploration is performed outside of the database system which necessitates huge data transfers. This impedes the processing such that real-time interactive exploration is impossible. These new hardware capabilities now allow to build a true computational database system that integrates deep exploration functionality at the source of the data. This will lead to a drastic shift in how users interact with data, as for the first time interactive data exploration becomes possible at a massive scale. Unfortunately, traditional DBMSs are simply not capable to tackle these new challenges. Traditional techniques like interpreted code execution for query processing become a severe bottleneck in the presence of such massive parallelism, causing poor utilization of the hardware. I pursue a radically different approach: Instead of adapting the traditional, disk-based approaches, I am integrating a new just-in-time compilation framework into the in-memory database that directly exploits the abundant, parallel hardware for large-scale data processing and exploration. By explicitly utilizing cores, I will be able to build a powerful computational database engine that scales the entire spectrum of data processing - from transactional to analytical to exploration workflows - far beyond traditional architectures.

Keywords: database management systems,query processing,query optimization
Development of a high quality stainless steel dowel for easy renovation and construction in façades, thermal insulation and solar panels sub-sectors (INNOFIXX)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Germany
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2017)
Start date: 2017-05-01
End date: 2017-08-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The building sector has been identified as one of the key sectors to achieve the 20/20/20 targets of the EU. Buildings are responsible for 40% of energy consumption and 36% of CO2 emissions. Studies show that renovations of existing buildings is one of the low-cost options to reduce emissions of CO2, and potentially improve energy security by reducing imports of fossil fuels. Additionally, the EU has set a target for all new buildings to be nearly zero-energy by 2020. Every building needs dowels to be constructed. Current dowels are an obstacle for the renovation of buildings, and addition of new technologies that support energy efficiency directives. INNOFIXX’s development, a new type of dowels for heavy duty loads and façades, has demonstrated to be fast and easy to assemble (it can reduce 20% of fixing costs in buildings), it can carry simultaneously vertical and horizontal loads, it covers a wide range of applications: fixing balconies, adding solar panels in the façades, repairing façades), it is able to add extra thermal insulation in buildings without the need to destroy current walls, it saves energy compared to existing dowels (it has demonstrated that INNOFIXX has lower heating bridges, which can save 2°C per dowel), it supports the European Energy directives in buildings (2010 Energy Performance of Buildings Directive, and the 2012 Energy Efficiency Directive), it can be recycled and re-used, and it has a long-life, they can last as long as the façade exists. INNOFIXX clearly supports the circular economy principle.

Keywords: development of a high quality stainless steel dowel for easy renovation and construction in fa ades,thermal insulation and solar panels sub sectors
SENSors and certifiable hybrid architectures FOR safer aviation in ICing Environment (SENS4ICE)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Ireland,Italy,Spain,Italy,Germany,Russian Federation,France,France,France,France,France,Czechia,United States,Brazil,Canada,United Kingdom
Call: Innovative technologies for improving aviation safety and certification in icing conditions (InCo flagship) (H2020-MG-2018-SingleStage-INEA, 2018)
Start date: 2019-01-01
End date: 2023-12-31
Duration (months): 60.0
Total project cost (EUR): 11959722.5
EU funding (EUR): 6587808.74
Participants: 22
Project status: SIGNED

Modern aeroplanes are well equipped to cope with most common icing conditions. However, some conditions consisting of supercooled large droplets (SLD) have been the cause of tragic accidents over the last three decades. It was proven that there are certain types of aircraft which are not robust against these conditions as ice can form on unprotected areas of the lifting surfaces leading to loss of control. Consequently, authorities addressed these safety concerns by issuing new certification rules under Appendix O to ensure that future aircraft remain controllable in these conditions and can exit safely upon detection. Hence, the key to increasing overall aviation icing safety is the early and reliable detection of icing conditions to allow the necessary actions to be taken by the flight crew. SENS4ICE (SENSors and certifiable hybrid architectures for safer aviation in ICing Environment) directly addresses this need for reliable detection and discrimination of icing conditions. It proposes that an intelligent way to cope with the complex problem of ice detection is the hybridisation of different detection techniques: direct sensing of atmospheric conditions and/or ice accretion on the airframe, combined with indirect techniques in which the change of aircraft characteristics with ice accretion on the airframe is detected. SENS4ICE will address the development, test, validation, and maturation of the different detection principles, the hybridisation - in close cooperation with regulators to provide an acceptable means of compliance - and the final airborne demonstration of technology capabilities in relevant natural icing conditions. The contribution of SENS4ICE to increase aviation safety will be achieved by an international consortium of 20 partners (13 EU, 7 non-EU) with contributions from Brazil, Canada, Russia and the US. The 4-year project requests an overall EU-funding of 6.6M€ and benefits from a further 5.4M€ of activities being provided by the non-EU partners.

Keywords: icing detection technologies,appendix o,supercooled large droplet,flight test campaign,icing characterisation,weather hazards,passenger safety,means of compliance,icing certification