Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Smart signaling system to increase road safety (Sislum)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2019-11-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Walking is 36 times more dangerous than driving, and 300 times more dangerous than flying. The first road crossing was invented in the 1930’s and remain almost the same since then. Each year road crashes generates around 95,000 fatalities and 2.4 million injuries only in EU region. 90 % of crashes are linked to human error, with pedestrians and riders constituting the main victims (39% of all deaths in road crashes) due to primarily inadequate visibility of pedestrians and vehicle speed. The problem remains unsolved due the limitations of current signs and warning technologies, such as: Ineffectiveness over time due to the temporary tunnel vision issue; Low tolerance to extreme weather conditions; Lack of incorporated Intelligent Transport Systems (ITS). Many of current signaling systems deform road surface/bent the sidewalks after continuous vehicle transit over them or require complex maintenance operations with high return on investment. In response to these challenges, Innvoaciones SP3 is bringing Sislum to the market: an emerging lighting system to increase road safety; promoting “smart mobility” through maximum crosswalk visibility and becoming a key enabler device to reduce road accidents up to 70%. According the audit performed by a certified authority, due to its potential impact in accident reduction, Sislum is recommend being installed in areas with more vulnerable users, such as in schools’ areas, pedestrian crossings, level crossings, bike paths, bus stops, parking exits, airports, and police stations among others. Sislum has already been tested in different road sections in 3 municipalities in Spain, including testing for analytics of the data generated by the application, with a positive outcome of increasing visibility up to 800m. Our goal is to reach the market by 2022 and expand globally, in order to make road and especially pedestrian crossings safer worldwide.

Keywords: road safety,intelligent transport systems,road fatalities reduction,tunnel vision,safe roads,road infrastructure management
Detection of Various Cancer Types for Screening and Diagnosis through Blood Samples with Epigenetic Biomarkers Panels (EPICHECK)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: Israel
Call: Clinical research for the validation of biomarkers and/or diagnostic medical devices (H2020-SMEINST-1-2015, 2015)
Start date: 2015-10-01
End date: 2016-03-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Nucleix developed a revolutionary platform for the development of Methylation Bio-markers and Bio-Marker panels for screening (early detection of disease) and diagnosis based on epigenetic markers. The platform identifies changes in specific methylation locations of DNA extracted from body fluids such as – urine, blood, stools and sputum. A Bio-Markers panel goal is to distinguish between sick and healthy individuals. The company’s expertise include the identification of the specific loci, comprising a panel of markers that can work in multiplex and generate highly accurate test. Nucleix technology was proven to be extremely sensitive and specific in its first application. Nucleix focuses initially on the field of cancer detection and screening. Cancer cost the EU €126 billion in 2009, which was 1.07% of EU GDP. 2.45m People in the EU were diagnosed with cancer in 2008, when 1.23 million people in the EU died from cancer in 2008. This is one of the most significant public health issues in the world and in the EU. Nucleix first product, Bladder EpiCheck is a urine test for the detection of Bladder Cancer. It is aimed for monitoring bladder cancer patients as this is a disease with high recurrence rate and requires tight surveillance. This product will be launched in Q4 of 2015. The test is based on a panel of 15 non-overlapping Methylation markers at loci that were identified, developed and owned by the company. This product which has better sensitivity and specificity than any other non-invasive test is a proof of the company’s ability to translate its technology to applicable products. The company plans to develop EPICHECK - diagnostic kits using multi-loci panel of markers, for the detection and screening of lung cancer and colorectal cancer in blood samples – which is the subject of this applications. EPICHECK will be launched rapidly, and will provide revenues of over 320m Euro in its 5th year of commercial activities.

Keywords: detection of various cancer types for screening and diagnosis through blood samples with epigenetic biomarkers panels
High temperature superconductivity and the Catch-22 conundrum (CATCH-22)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Netherlands,United Kingdom
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2019-10-01
End date: 2025-03-31
Duration (months): 66.0
Total project cost (EUR): 2495628.75
EU funding (EUR): 1631955.0
Participants: 2
Project status: SIGNED

CATCH-22 sets out to resolve the mystery of the cuprate high temperature superconductors. Hailed as one of the major discoveries of the 20th Century, its central mysteries – the pairing mechanism, the origin of the ‘pseudogap’ and the nature of the ‘strange metal’ phase, have remained elusive for over 30 years. Typically, what scatters electrons also binds them into pairs, and in the cuprates, the strong pairing interaction manifests itself in the strange metal phase as intense scattering, so strong in fact that it drives the electronic states required for pairing incoherent. In other words, what first promotes high temperature superconductivity ultimately destroys it! This logical paradox is the Catch-22 conundrum. CATCH-22, the program, comprises three parts. Part 1 will explore the fate of electronic states within the strange metal phase by studying how the metallic response diminishes across universal bounds, both as a function of temperature and interaction strength, through momentum-averaged electrical conductivity and thermal diffusivity studies and momentum-resolved photoemission spectroscopy. Part 2 will seek to access the ground state of optimally doped cuprates for the first time, by applying intense current and laser pulses to ultra-thin samples in a high magnetic field. The latter, if successful, will open up a new frontier in which intense THz light and intense magnetic fields combine to access the terra incognita of hidden phases. Finally, Part 3 will explore the origins of the strange metal at the edge of the superconducting dome and search for manifestations of incoherence in other strange metals in an attempt to unify the governing principles. Given that the central mysteries are intertwined – the strange metal is a precursor to the pseudogap which in turn leads to superconductivity - CATCH-22 will aim to bring significant new insight into all three and pave the way, finally, for a coherent phenomenological model for cuprate superconductivity.

Keywords: none
Functional ecology of the plant-fungus interface: Harnessing evolutionary genomics, transcriptomics and experimental ecology to dissect communication and nutrient exchange in a mutualistic symbiosis (OakMycEvo)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-10-01
End date: 2021-09-30
Duration (months): 24.0
Total project cost (EUR): 174806.4
EU funding (EUR): 174806.4
Participants: 1
Project status: CLOSED

This proposal aims to construct an evolutionary framework for the molecular interactions between ectomycorrhizal fungi and their plant hosts. Ectomycorrhizal (ECM) symbiosis is a mutualistic association between fungi and trees that is founded on reciprocal exchange of nutrients, facilitating growth in nutrient-limited or otherwise stressful environments. The symbiosis has evolved independently in many fungal clades, raising questions about its evolvability and the ecological redundancy of different ECM fungi. The ability of one ECM fungus to functionally replace another is especially salient in light of environmental change and loss of biodiversity. What components of communication between fungus and plant are conserved among ECM species? How conserved are molecular interactions at different phylogenetic scales? What are the molecular mechanisms responsible for phenotypic variation? ECM fungi from the genus Amanita will be grown together with the host Quercus robur (pendunculate oak). Q. robur displays endogenous rhythmic growth with alternating root and shoot flushes, distinct physiological states of growth that influence interactions with ECM fungi. The fungal strains are selected to survey variation i) between different Amanita ECM species and ii) in comparison with closely related saprobic Amanita sp., using a phylogenomic approach. We will profile genes expressed on both fungal and plant side at different time points: during mycorrhizal development and in mature mycorrhizas, while separating each time point into periods of root flush and shoot flush. We will profile a compendium of traits related to the functioning and success of ECM symbiosis at each developmental stage. Together these results will allow us to develop a detailed mechanistic view of the genes and pathways underlying ECM symbiosis, their evolutionary dynamics across a phylogenetic gradient of fungal partners and their impact on the different physiological stages of plant growth.

Keywords: ectomycorrhizal symbiosis,genome evolution,regulatory networks,convergent evolution,evolutionary transitions,coevolution,plant fungal interactions
Sheet metal forming testing hub (FormPlanet)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Advanced materials
Action type: Innovation actions
Countries involved: Spain,Italy,Spain,Spain,Germany,Italy,Sweden,Türkiye,Sweden,France,Czechia,United Kingdom,United Kingdom
Call: Open Innovation Test Beds for Characterisation (IA) (H2020-NMBP-TO-IND-2018, 2018)
Start date: 2019-01-01
End date: 2021-12-31
Duration (months): 36.0
Total project cost (EUR): 7713022.5
EU funding (EUR): 6907432.5
Participants: 19
Project status: CLOSED

FormPlanet addresses processability and part performance in the sheet metal manufacturing sector. The sector faces new challenges related to the manufacture of high performance parts with new high strength materials. Such high strength makes them processing sensitive, so forming parameters and sheet properties must be assessed to assure 0-deffect production and part quality. Forming problems in processing sensitive materials are associated with unexpected defects that cannot be predicted at the product design stage using traditional experimental or computational approaches. The aim of FormPlanet is to develop and demonstrate an integrated ecosystem offering novel testing methodologies to characterise sheet properties, predict part performance and prevent production loses to the sheet forming industries to tackle the upcoming challenges in formability of processing sensitive materials. New testing methodologies, and FE approaches to predict formability and part performance as well as monitoring and inspecting NDT will be developed and adapted to the sector needs. The potential of the novel approach will be proved by studying industrial demonstrators, selected to prove the solutions for relevant industrial problems for the all value chain, and to reduce cost and time-to market of materials and products. 9 industrial partners representing the sheet metalworking industry value chain will validate the approach. A solid, sustainable and simple organisational structure will be implemented for the future Test Bed service provision, based on experienced partners with strong business focus. The Test Bed FormPlanet time to market is estimated by the end of the project, when technical and business infrastructure and marketing strategy are implemented. Maximum impact will be ensured through well-balanced dissemination, standardarisation, communication, materials information management, stakeholders engagement and networking and by the exploitation of the Test Bed.

Keywords: sheet metal forming,metal alloys,advanced characterisation tests,fracture mechanics,edge cracking,crashworthiness,formability,test bed,in line process monitoring,time to market reduction
Identifying biomarkers of stress-induced neurophysiological changes and emotion regulation deficits to predict relapse during nicotine abstinence (BioNic)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Cyprus
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-01
End date: 2025-05-01
Duration (months): 24.0
Total project cost (EUR): 145941.12
EU funding (EUR): 145941.12
Participants: 1
Project status: SIGNED

Tobacco smoking is the primary preventable cause of death and disability worldwide. Although there are numerous pharmacotherapies and psychological interventions to assist with smoking cessation, most users relapse following abstinence, while only ~15% of abstinent individuals achieve long-term abstinence of more than 6-12 months. Therefore, there is a need to identify smokers at higher risk for relapse, to facilitate the development of personalized pharmacotherapies for the treatment of nicotine addiction. In this context, BioNic proposes an interdisciplinary approach to examine the unique and/or interactive effects of trait-like vulnerability factors (baseline emotion regulation ability) and biomarkers of state responses to stress (emotion regulation and synchronized neural activation response to stress) prior to smoking cessation, on cravings, abstinence adherence, and response to an established smoking cessation intervention. During this fellowship, the in-depth expertise of the researcher in studying mechanisms underlying relapse to abuse drugs following abstinence using preclinical models, combined with the expertise on human psycho- and neuro-physiological measurements that he will acquire at the Host lab will provide data and publications that will contribute to the identification of biomarkers predicting nicotine relapse vulnerability prior to smoking cessation. This work will unveil a new critical link between emotion regulation deficits and neural activation changes that together will predict maintenance of smoking abstinence. Overall, this fellowship will strengthen the academic profile of the Researcher and will act as a leverage towards securing future research funding and securing a tenure track position in Europe.

Keywords: emotion regulation,electroencephalography,nicotine addiction,relapse,biomarkers
architectuRe for an Internet For Everybody (RIFE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Future Internet: Software, hardware, Infrastructures, technologies and services
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Cyprus,Finland,Switzerland,France,United Kingdom,United Kingdom,United Kingdom
Call: Smart Networks and novel Internet Architectures (H2020-ICT-2014-1, 2014)
Start date: 2015-02-01
End date: 2018-03-31
Duration (months): 38.0
Total project cost (EUR): 3185001.25
EU funding (EUR): 2930626.25
Participants: 9
Project status: CLOSED

RIFE addresses the major societal challenge of providing affordable Internet access to those who cannot afford it by solving the technological challenge to increase the efficiency of the underlying transport networks and the involved architectures and protocols. The RIFE solution will harness unused transmission capacity, combined with placing content caches and service functionality closer to the user and will use heterogeneous transmission opportunities that range from localized mesh and home networks over well-connected ISP backhauls to scarce satellite resources. RIFE will build upon recent advances on information-centric and delay-tolerant networking by developing optimized dissemination strategies for the involved transport networks, unified within a novel communication architecture that will provide clear abstractions to application developers. We will develop, deploy and showcase our solution in a real-life setting within a large-scale community network in Spain, demonstrating the technology and economic opportunities that the RIFE platform provides. We will complement our real-life testbeds with emulation scenarios to enable the evaluation of our novel resource management schemes at scale, while integrating with our prototype platform. On the economic side, we will develop business opportunities for local authorities as well as backhaul network providers to create a sustainable value chain by introducing virtual network operators that utilize the under-used capacity in a new business relationship with local customers, enabling novel and often socially-driven business models. The involvement of a technology, equipment, as well as satellite and community network provider will allow for maximizing the commercial exploitation of RIFE within real deployments and towards standard communities within the IETF/IRTF and beyond, placing RIFE in the centre of a growing community of practitioners that all share the same goal: making the Internet affordable to everybody!

Keywords: affordable internet access,information centric and delay tolerant networking,novel communication architecture
Tools for the Investigation of Transactions in Underground Markets (TITANIUM)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Fight crime, illegal trafficking and terrorism, including understanding and tackling terrorist ideas and beliefs
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Austria,Germany,Spain,Spain,Germany,Finland,France,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Technologies for prevention, investigation, and mitigation in the context of fight against crime and terrorism (H2020-SEC-2016-2017-1, 2016)
Start date: 2017-05-01
End date: 2020-04-30
Duration (months): 36.0
Total project cost (EUR): 4991600.0
EU funding (EUR): 4991600.0
Participants: 16
Project status: CLOSED

TITANIUM will develop novel methods and technical solutions for investigating and mitigating illegitimate activities (relating to either crime or terrorism) involving virtual currencies and/or underground market transactions. Specifically, the project will: * Establish a research and development environment that enables close and continuous collaboration between researchers, developers, legal experts, and law enforcement stakeholders in several European countries and regions * Analyse legal and ethical requirements for tools and services, elicit technical requirements from LEA stakeholders, and establish a development ecosystem that ensures compliance with these requirements and supports the generation of court-proof evidence * Implement tools for the automated aggregation of data from diverse sources, including the dark web, the surface web, and other sources and devices obtained through legal warrants, using multi-modal adaptive crawlers, stealth facilities, and smart filters * Provide services for the simulation of criminal activities and the generation of synthetic data * Investigate customizable heuristics, which can operate across different virtual currency transaction ledgers and identify clusters of addresses that are likely to belong to the same real-world entity * Apply novel techniques based on machine-learning and deep neural networks for revealing patterns, detecting anomalies, and identifying tumblers and mixers used for money laundering * Deploy forensics tools and services to partner LEAs and conduct Field Labs to assess the effectiveness, ethical and legal compliance, and overall impact of the results and to validate those results at technology readiness level (TRL) 6 or higher * Prepare curricula and carry out training and joint exercises that will facilitate the take-up of TITANIUM technologies by LEAs across Europe * Allow European SMEs and RTOs to develop cutting edge tools, to access LEA markets, and to strengthen European competitiveness

Keywords: virtual currency,cryptocurrency,bitcoin,darknet,dark web,underground markets