Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
DEMOnstration of large SOFC system fed with biogas from WWTP (DEMOSOFC)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Innovation actions
Partnership: FCH2 (Art-187)
Countries involved: Italy,Finland,United Kingdom
Call: Large scale fuel cell power plant demonstration in industrial/commercial market segments (H2020-JTI-FCH-2014-1, 2014)
Start date: 2015-09-01
End date: 2020-10-31
Duration (months): 62.0
Total project cost (EUR): 5905336.25
EU funding (EUR): 4492561.0
Participants: 6
Project status: CLOSED

Energy Context and EU position The “Europe 2020” strategy promotes the shift towards a resource-efficient, low-carbon economy to achieve sustainable growth. The European policies on energy and sustainability are thus contributing to the diversification of the primary energy mix and to the introduction of distributed power technologies with high efficiency and low carbon emissions. , From the point of view of energy policy, the European Strategic Energy Technology (SET) Plan for 2020 identifies Strategic Technologies Focus on the following priorities: • Energy Efficiency: high efficiency conversion devices represent elements of a higher efficiency portfolio • Renewable Energy: traditional RES (solar, wind, hydro) but also biogenous fuels (biogas, bio-syngas, bio-fuels) and new synthetic vectors (H2, synthetic NG,….) • Carbon capture and storage: mitigation of CO2 emissions (related to efficient energy conversion devices, and improved adoption of RES fuels) and CO2 recovery • Smart Grid: large topic, in which several technologies are included (energy storage, ICT intelligence of the grid, prosumer….), among which the concept of distributed CHP plant gets an important role DEMOSOFC objectives 1. DEMO and deep analysis of an innovative solution of distributed CHP system based on SOFC, with high interest in the industrial/commercial application representing the best solution in the sub-MW distributed CHP in terms of efficiency and emissions 2. DEMO of a distributed CHP system fed by a biogenous CO2 neutral fuel: biogas from anaerobic digestion 3. DEMO in a real industrial installation 4. DEMO of the high achievements of such systems: electrical efficiency, thermal recovery, low emissions, plant integration, economic interest for best use of renewable fuels in a future of decreasing incentives 5. EXPLOITATION and BUSINESS analysis of replication of this type of innovative energy systems 6. DISSEMINATION of the high interest (energy and economic) of such systems

Keywords: sofc,biogas fuel,medium size,demonstration,industrial site
Early Origins of Social Cohesion in Increasingly Diverse Societies (KIDSNGROUPS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance and management
Countries involved: Germany,Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-10-01
End date: 2027-09-30
Duration (months): 72.0
Total project cost (EUR): 1999992.0
EU funding (EUR): 1407391.45
Participants: 2
Project status: SIGNED

In-group favouritism and out-group discrimination are ubiquitous phenomena, threatening social cohesion in diverse societies. Notwithstanding growing urgency, we lack a systematic understanding of the causes and consequences of in-group out-group biases, or to put it more broadly, of social cohesion. KIDSNGROUPS will open frontiers to advance our knowledge on social cohesion by focusing on the early life cycle, and thus the most formative years in people’s life. Its main objective is to break ground regarding the causal origins of in-group out-group preferences. For this purpose, it will study the role of the family (vertical socialization) and other socialization processes like imitation and learning (horizontal socialization) in shaping children’s in-group out-group preferences. Moreover, it will shed novel light on the economic relevance of social cohesion. To the extent that in-group favouritism and out-group discrimination prevent children from helping each other, they may hamper children’s welfare, and thus the future of diverse societies. Striving to provide a comprehensive picture of the origins and the impact of social cohesion, KIDSNGROUPS will draw upon methods from the frontier of various research fields. In particular, it will propose an innovative combination of i) experimental methods to study in- and out-group phenomena, ii) administrative records to get access to large-scale, non-selected samples and hands on high quality measures of children’s human capital, and iii) state-of-the-art econometric techniques to infer causality. In so doing, KIDSNGROUPS will open up new avenues for any science interested in people’s behaviour. In summary, KIDSNGROUPS will not only advance in a creative and significant manner an active research area, it will also impact public policy by generating essential insights on one of the most urgent topics on Europe’s political agenda.

Keywords: diverse society,early childhood,in group favouritism,out group discrimination,vertical and horizontal socialization
The Free French and the British Forces: a case study of transnational military cooperation, 1940-1945 (FFABFORCE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-11-01
End date: 2018-10-31
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

FFABFORCE has the following research objectives: to assess the British approach to organising effective multinational forces during the Second World War, using the Free French as a case study, and to analyse the responses of the Free French to their host’s efforts to integrate them. My career objectives are to become a European Research Leader in the university sector and to obtain the skills to work in the private sector as an editor in a history publisher. The research objectives will be achieved by examining the relevant literature and by doing archival research in at least 11 archives in 3 countries. The sources examined will include government documents, personal papers, diaries and memoirs. The career objectives will be achieved by: training through research under the mentorship of Prof Guillaume Piketty, dissemination activities, training courses on Collaborative Projects, Open Access, ERC grant proposals, data management and interview preparation. This will give me the required skills in advanced project management, teamwork, communication and technical know-how. The research will also help me reach a position of professional maturity, as FFABFORCE will result in my second monograph and deepen my expertise in modern history. My innovative project will contribute to one of the key drivers of Horizon 2020: to develop new knowledge and enhance the skills of excellent researchers. Moreover, one of the societal challenges outlined in Horizon 2020, ‘Europe in a changing world’, aims at ‘supporting inclusive, innovative and reflective European societies’. FFABFORCE will contribute to this goal by increasing academic & public understanding of the transnational nature of the Allied war effort during the Second World War and by demonstrating the weakness of the nation-centric approach to understanding the war. In this way, my research will act as a counter-weight to extreme nationalists who deliberately distort the history of the war for their own political ends.

Keywords: european exiles in the british armed forces franco british relations second world war transnational history military history comparative history social history cultural history
AGLARIS: The First Fully-automated Bioreactor for Large Scale Human Stem Cell Production through an Iterative Process. (AGLARIS)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Treating and managing disease
Action type: SME instrument
Countries involved: United Kingdom
Call: Supporting innovative SMEs in the healthcare biotechnology sector (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-06-01
End date: 2016-09-30
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In order to meet the expanding market for human stem cells (HSCs) in cell therapy, automated, cost-effective, large-scale manufacturing processes are required. AGLARIS Project is centered in the market launch of the patented AGLARIS BIOREACTOR for large-scale HSCs production, which perfectly meets the requirements for cell-based therapeutic products. Current bioreactors for HSCs producers consist in attempts to adapt bioreactors derived from traditional bioprocesses, but its use has not been widespread as they are not optimized for HSCs production. The automation level of bioreactors is limited to an initial quantity of 20M cells. As the cell sample from biopsies contains 0.5-1M cells, a previous manual cultivation is always required to reach the minimum quantity. This step affects cell quality. AGLARIS operates with the quantity of cells coming directly from biopsy, completely eliminating the manual pre-cultivation requirement. Moreover, current Bioreactors are limited to 300M cells per cell batch. The common are based on hollow-fibers as the substrate in which cells are anchored for growing. Once they reach its maximum capacity, cells need to be detached by using chemical and enzymatic reagents. AGLARIS operates in an iterative manner reaching 5000M cells without dividing the cultivation process in several batches. It is based on microcarriers which allows cell detachment by a simply small variation of temperature, avoiding adverse side effects. Additionally, for a complete disease management, the production of 600M cells on average is required. When produced manually, the cultivation of 600M cells can reach 9.347€, and by using hollow-fiber Bioreactors 15.643€. AGLARIS optimized culture process produces cell yields with the correct quality while using minimal amounts of expensive reagents, allowing the price to decrease to 1.015€ per 600 M of cells, meaning that costs will be reduced by up to 91% on average.

Keywords: bioreactor,human stem cells,cells manufacture,cell therapy,regenerative medicine
Development of GRASP radiative transfer code for the retrieval of aerosol microphysics vertical-profiles from space measurements and its impact in ACE mission (GRASP-ACE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Ukraine,Germany,Spain,Spain,Argentina,Austria,Spain,Russian Federation,China,Belarus,France,France,United States
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2017, 2017)
Start date: 2018-03-01
End date: 2023-08-31
Duration (months): 66.0
Total project cost (EUR): 877500.0
EU funding (EUR): 877500.0
Participants: 19
Project status: SIGNED

This project deals with reducing the uncertainties associated with the knowledge of aerosol microphysical vertical profiles worldwide through the use of new space-borne measurements. This objective links with the goal of the last IPCC 2013 to reduce uncertainties in aerosol direct effects, particularly in the knowing of absorption profiles. The approach we plan to develop is the development and applicability of the Generalized Retrieval of Atmosphere and Surface Properties (GRASP) for new space borne systems. GRASP has been already applied successfully to the POLDER/PARASOL system providing column-integrated aerosol microphysics and absorption. However, the new LIDAR space-borne sensors open new possibilities. To that end, we plan to study the details in constraints of the current techniques for the retrieval of aerosol microphysics from multi-wavelength lidar alone (known as the 3b+2a configuration), and will make evaluation studies versus in-situ instruments from large field campaigns such as DISCOVER-AQ and SEACR4S from NASA or SHADOW from the University of Lille. However, lidar measurements are difficult and usually presents low signal-to-noise ratio, particularly during daytime. We plan here to develop a joint inversion that uses combine measurements of lidar and polarimetric space-borne systems. Such approach is the core of the upcoming Aerosol-Clouds-Ecosystems (ACE) NASA mission. The development of this task will involve the use of synthetic database simulated using the NASA GEOS-5 model which will be used as reference. Different configurations of lidar and polarimeters will be studied to invert microphysical parameters. The results of this task will be also used for defining cost-effective ACE mission. Also, joint inversion will be evaluated using experimental measurements on NASA field campaigns that include airborne lidar systems such as HSRL-2 and Airborne Cloud-Aerosol Transport System (ACATS) and polarimeters such as the Multiangle SpectroPolarimetric

Keywords: aerosol microphysical properties vertical profiles
Southern Ocean Overtuning Fingerprint Experiment (SOFIE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2021-09-01
End date: 2023-08-31
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: CLOSED

The Southern Ocean overturning circulation exerts a powerful influence on Earth’s climate, and SOFIE is the first project seeking to detect and objectively measure the hydrographic fingerprint of changes in this overturning.The deep waters upwelling in the Southern Ocean account for up to half of the annual oceanic uptake of anthropogenic carbon from the atmosphere, dominate the global oceanic heat uptake with up to three quarters of the additional heat influx to the ocean occurring south of 30°S, and are a rich source of the nutrients that fertilise the majority of global ocean biological productivity north of 30°S.According to numerical studies, there is consensus that in response to increased westerly winds such as those occurring within contemporary climate change, variations in the overturning circulation are likely to be substantial.However, there is no established approach to provide observational evidence that these variations have occurred or are occurring in oceanographic measurements;and the lack of such an approach stems from the uncertain fingerprint of Southern Ocean overturning circulation changes on measurable oceanographic variables.Based on preliminary results supported by recent studies, SOFIE proposes that changes in the overturning circulation affect discernibly the ocean interior density structure from surface to depth across the Southern Ocean.We will rigorously test this hypothesis in the state-of-the-art numerical NEMO-OPA model, and assess in-situ evidence of overturning changes from the pan–Antarctic Argo network.To do this, SOFIE will combine model diagnostics of the Southern Ocean overturning circulation with the application to the model and in-situ fields of a novel algorithm characterising the vertical structure of the ocean.Given the ocean overturning’s sensitivity to changes in atmospheric forcing,SOFIE results will be a major step to constrain the changing ability of the Southern Ocean to slow down the rate of global climate change.

Keywords: southern ocean overturning circulation,ocean interior density structure,climate change
Decisions in metabolic inflammation of the liver: Adhesive interactions involved in leukocyte retention and resolution of inflammation in metabolic-inflammatory liver disease (DEMETINL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2015-CoG, 2015)
Start date: 2017-01-01
End date: 2022-10-31
Duration (months): 70.0
Total project cost (EUR): 1953250.0
EU funding (EUR): 1953250.0
Participants: 1
Project status: CLOSED

Resolution of acute inflammation, involving limiting further leukocyte recruitment, apoptosis and clearance of inflammatory cells via macrophages as well as egress of the inflammatory cells, is operative in acute inflammation but dysfunctional in chronic inflammatory disease. In the latter scenario, the retention and activation of leukocytes in the inflamed tissue linked with failure to resolve inflammation contributes to perpetuation of organ damage and loss of homeostasis. Interestingly, persistent inflammation in insulintarget organs, such as the adipose tissue and the liver in the context of obesity significantly contributes to development of insulin resistance (IR), diabetes and non-alcoholic fatty liver disease (NAFLD). So far, investigations have mainly addressed obesity-related inflammatory mechanisms in the AT and rather less in other metabolic organs, e.g. the liver. Therefore, the aims of this proposal are: (i) To characterize in the context of obesity-related metabolic disease novel processes mediating inflammatory cell retention, especially in the liver. In this context, we will also address the novel hypothesis that adhesive interactions of inflammatory cells (with e.g. parenchymal cells) in the metabolically challenged environment of obese organs may activate them via alterations in their cellular metabolism, thereby contributing to perpetuation of inflammation. (ii) To understand resolution of inflammation including inflammatory cell egress from metabolic organs, especially from the liver in metabolic-inflammatory disease. To this end, we will also utilize models of acute inflammation, which is capable to resolve, in order to understand resolution principles and apply them to non-resolving metabolic-inflammatory disease. In this regard, we will also assess the therapeutic potential of novel inflammation-modulating factors identified by our lab.

Keywords: inflammation,leukocyte adhesion,obesity
A Responsible Research & Innovation Model for Impact investment & Responsible Startups (RRIstart)

Framework: Horizon 2020 — Science with and for Society
Action type: Research and Innovation actions
Countries involved: Italy,Greece,Belgium,Netherlands
Call: Bottom-up approach to build SwafS knowledge base (H2020-SwafS-2020-1, 2020)
Start date: 2021-03-01
End date: 2024-02-29
Duration (months): 36.0
Total project cost (EUR): 1099125.0
EU funding (EUR): 1099125.0
Participants: 6
Project status: SIGNED

RRIstart responds to the EU efforts to foster impact investment (investment that delivers social, environmental and economic benefits) by developing an innovative RRI-based model for startups, complemented by an RRI-based impact investment indicator list in a multi-stakeholder (beyond quadruple helix) context. Through RRIstart, the consortium aims to demonstrate the value of RRI for the STEM entrepreneurship ecosystem. At the moment, startups and investors do not adopt existing RRI principles and indicators due to the limited compatibility of existing RRI models (tailored mostly for large organizations). Nevertheless, by adopting a lean/agile approach to RRI embedment, RRIstart proposes a novel RRI model for startups blended with novel RRI-based impact investment indicators. RRIstart tests the developed innovation through a translational piloting approach (from lab to market). Three pilots will be organized (on environmentally sustainable startups from Northern Europe, 3D printing & advanced materials in Italy and bioeconomy (agrifood) in Greece). In each pilot, extended quadruple helix actors will be involved in order to assess the feasibility of embedding RRI in startups and to facilitate (public and private) impact investment through the RRI-based indicator set. By adopting a multi-disciplinary approach in a multi-sectoral STEM context, RRIstart will update the SwafS knowledge base through the following: contributing to 9 MoRRI indicators and 9 SDGs; boosting societal engagement towards STEM startups; fostering the recruitment of talent for STEM startups; pairing scientific excellence with social awareness and responsibility by facilitating RRI-based startups and impact investment; creating new market opportunities; bring society closer to science and innovation through impact investment (show-casing the clear benefits of societal engagement in innovation development); and overall, making EU startups and investors more RRI-aware.

Keywords: impact investment,rri knowledge base,startups,indicators,responsibility,business model innovation,quadruple helix,un sdg,social impact,stem
Personalised Risk assessment in febrile illness to Optimise Real-life Management across the European Union (PERFORM)

Framework: Horizon 2020 — Societal Challenges
Programme: Health, demographic change and wellbeing
Theme: Health care provision and integrated care
Action type: Research and Innovation actions
Countries involved: Austria,Germany,Spain,Switzerland,Greece,Slovenia,Latvia,France,Netherlands,Netherlands,Netherlands,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Piloting personalised medicine in health and care systems (H2020-PHC-2015-two-stage, 2015)
Start date: 2016-01-01
End date: 2021-06-30
Duration (months): 66.0
Total project cost (EUR): 18467697.76
EU funding (EUR): 17997665.5
Participants: 20
Project status: CLOSED

The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are treated with antibiotics for presumed bacterial infection when, in fact, they are suffering from self-resolving viral infection. We aim to improve diagnosis and management of febrile patients, by application of sophisticated phenotypic, transcriptomic (genomic, proteomic) and bioinformatic approaches to well characterised large-scale, multi-national patient cohorts already recruited with EU funding. We will identify, and validate promising new discriminators of bacterial and viral infection including transcriptomic and clinical phenotypic markers. The most accurate markers distinguishing bacterial and viral infection will be evaluated in prospective cohorts of patients reflecting the different health care settings across European countries. By linking sophisticated new genomic and proteomic approaches to careful clinical phenotyping, and building on pilot data from our previous studies we will develop a comprehensive management plan for febrile patients which can be rolled out in healthcare systems across Europe.

Keywords: biomarkers,antibiotic resistance,stainability of health systems,public health,febrile illness,bacterial infection,viral infection