Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
AYURVEDIC BIOACTIVE COMPOUNDS STABILIZED PICKERING DOUBLE EMULSIONS- FABRICATION AND IN VITRO EVALUATION (Nano Structured Emulsion Foods)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-07-01
End date: 2017-06-30
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Ayurveda is ~5000 years old healing science which was originated from India with the concept of use of natural ingredients for health purposes such as curcumin, quercetin etc. Ayurvedic bioactive compounds (ABC) can potentially be used to control chronic health problems such as obesity by the targeted and controlled release of bioactives. The use of these bioactives in complex food products is limited as they are sensitive to various factors such as pH, temperature etc. Recent advancement in application of nanotechnology to food product development offers an opportunity to allow enriching food products with bioactive molecules isolated from ayurveda or any other medicine system by applying the learnings developed for pharmaceutical nano drug delivery technology, in particular “nanocrystals technology”. The project has two interrelated objectives: (1) fabrication of nanocrystals of ABC to modulate solubility, wettability etc.; (2) use of these nanocrystals as edible Pickering particles to control emulsion functionality (stability, rhelogy, and digestibility). As the particles will be used for stabilization, and also as bioactive (i.e. dual functionality) this system will be unique. The interfacial layer of ABC will allow the control of the emulsion functionality without using high concentration of emulsifiers which are generally used to stabilize emulsions. Fatty acids in emulsion will help improve the bioavailability of ABC. Success in this project will seed and lead the development of innovative formulation strategy for healthy food product development by reducing the use of synthetic emulsifiers (PGPR) thus impacting on consumers and industry. This will be possible by combining the pharmaceutical drug delivery technology expertise of the experienced researcher with the food delivery expertise and more engineering oriented approach of the supervisor with the intersectoral collaboration between University of Birmingham & Unilever, Netherlands.

Keywords: obesity,ayurvedic bioactives,pickering double emulsion,lipolysis,bioavailability
Clip-off Chemistry: Design and Synthesis of New Materials via Programmable Disassembly of Reticular Materials (CLIPOFF-CHEM)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Spain
Call: ERC ADVANCED GRANT (ERC-2020-ADG, 2020)
Start date: 2021-10-01
End date: 2026-09-30
Duration (months): 60.0
Total project cost (EUR): 2505645.0
EU funding (EUR): 2505645.0
Participants: 1
Project status: SIGNED

Historically, innovations in synthetic methods and reactions have changed the way scientists think about designing and synthesizing materials and molecules. Indeed, novel synthetic methods not only unlock access to previously unattainable structures, but also inspire new concepts as to how we design and build materials to address global social, economic and industrial needs. The project that I propose here, CLIPOFF-CHEM, centers on the demonstration of a novel synthetic methodology that I have named Clip-off Chemistry. Unlike most state-of-the-art synthetic approaches, which use bottom-up strategies to link atoms and molecules through the formation of new bonds, Clip-off Chemistry is based instead on the selective cleavage of existing bonds in reticular materials, providing precise spatial control over bond cleavage. In reticular materials, this cleavage can be programmed to enable the synthesis of limitless materials varying by composition (from organic to metal-organic), dimensionality (from 3-D to 0-D) and size-scale (from macro- to nanoscale). Accordingly, in CLIPOFF-CHEM, I will employ clip-off synthesis to prepare a diverse collection of new materials and molecules, including new 3-D metal-organic frameworks (MOFs), low-dimensional (2-D and 1-D) materials, organic polymers, metal-organic polyhedra (MOPs), complexes and macrocycles. Our work will encompass 1) synthesis of the reticular material precursors (MOFs, COFs and MOPs) that incorporate non-cleavable and cleavable (alkene/alkyne) groups in precise positions of their structures; and 2) cleavage of alkene/alkyne groups through ozonolysis to produce the targeted materials. As the resultant products will be novel, we will also endeavor to identify and characterize any unprecedented structural or functional properties of them. I believe that CLIPOFF-CHEM will provide the global scientific community with an innovative methodology for the design and synthesis of new functional molecules and materials.

Keywords: metal organic frameworks mofs,covalent organic framework cofs,metal organic polyhedra mops,reticular chemistry,ozonolysis,porosity
Innovative tools for offshore wind and DC grids (InnoDC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,Spain,Belgium,Belgium,Belgium,Belgium,China,Denmark,Portugal,Denmark,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2017-09-01
End date: 2021-12-31
Duration (months): 52.0
Total project cost (EUR): 3740101.07
EU funding (EUR): 3740101.07
Participants: 16
Project status: CLOSED

Europe’s power system has seen significant changes in recent decades, notably the development of renewable energy sources. However, this transition is far from complete, and further changes are essential to make our energy system ready to play its part in realising the climate goals set at COP21. At present, renewable energy sources are increasing their share of electricity generation. This is particularly the case for offshore wind energy. InnoDC's 14 participants prepare 15 early career researchers to play their role in the energy transition that will take place over the next 20-40 years. The project focusses on the development of the electricity transmission system, targeting the connection of offshore wind, the integration of offshore wind with the existing power system (including the use of HVDC), and the operation of the future power system where large scale wind is connected to a hybrid AC and DC power system. Technological development for offshore wind is ongoing. This research project focusses on the models and methodologies for the integration of these new technologies (e.g. offshore wind turbines, VSC HVDC converters, long AC cables) into the power system. Challenges in these areas will be addressed in this project: firstly, these new devices behave inherently differently to traditional power system components. Secondly, the multi-actor/intersectoral nature of these systems means that they have distinct elements and devices interfacing with each other, each with limited information of the overall system. The project will train the researchers in developing prototype tools to aid the developers and users of these new energy systems. This training network aims to train the researchers of the future in the pivotal sector of renewable energy and grid technology, which is largely led by research and industry. This project prepares the researchers of tomorrow to maintain Europe’s position of leadership in renewable, smart energy and tackling climate change.

Keywords: offshore wind,grid connection,hvdc transmission,dc grids,innovation,tools,renewable energy
Automated photovoltaic cell and Module industrial Production to regain and secure European Renewable Energy market (AMPERE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Low-cost, low-carbon energy supply
Action type: Innovation actions
Countries involved: Germany,Italy,Italy,Germany,Switzerland,Switzerland,Switzerland,Norway,Hungary,France,United Kingdom
Call: Increasing the competitiveness of the EU PV manufacturing industry (H2020-LCE-2016-RES-IA, 2016)
Start date: 2017-05-01
End date: 2020-04-30
Duration (months): 36.0
Total project cost (EUR): 26557003.75
EU funding (EUR): 14952065.14
Participants: 17
Project status: CLOSED

Today’s world PV market is dominated by standard crystalline solar cells (so-called Al-BSF cells) and part of the market is shifting to PERC solar cells. The shift is obtained by introducing three additional process steps to the standard process (rear side cleaning, passivation and laser opening), and allows a gain of typically 1% absolute in efficiency. Next generation c-Si technologies should feature higher voltage solar cells with higher efficiency and less processing steps in the manufacturing, allowing for further cost reduction, both at the PV panel level and for the final cost of solar electricity. AMPERE focuses on technologies with such a potential and capitalizes on the high tech investments made in Europe over the last decade for establishing advanced manufacturing processes for crystalline silicon heterojunction (SHJ) solar cells and modules, on the development of hardware capable of coating at high speed and low cost homogeneous materials of high electronic quality. It also bases on the unique expertise gained in production of thin film modules, and in all hardware issues related to large area coatings in production environment, which can applied for the production of SHJ cells and modules. The final goal of the project is t the setting-up of a 100 MW full-scale automated pilot line in production environment at the 3Sun fab, while preparing the next steps to 300 MW and GW scale. The project will operate with the support of full technology platforms for solar cells at CEA and the platform for advanced module technologies at MBS. It will demonstrate practically the ultra-low cost potential of such manufacturing approaches, as well as the even more impressively low solar electricity generation costs thanks to high efficiency and/or intrinsic bifaciality of the selected technologies.

Keywords: heterojunction technology,automated production lines
cOmpRession of Genomic dAta to facilitate precision MedIcine (ORIGAMI)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: France
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2019-08-01
End date: 2020-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Healthcare is a worldwide challenge. To fight diseases, medicated treatments are common. However, statistics show that 3 out of 5 treatments are currently inadequate. Personalised Medicine is one of the fundamental discipline to fix those inefficient treatments. Based on DNA, genomic sequencing is performed to achieve a personalised diagnostic for the patient. Unfortunately, this type of medicine encounters some limitations. One of them is the astronomical amount of numerical genomic data that it generates. With these volumes, transferring, storing, archiving and analysing the data become an issue. To counteract these issues, ENANCIO has developed an algorithm, called Lena, to compress genomic data and improve the entire genomic data workflow. ENANCIO aims to provide a solution to improve the transfer and storage of those data, but also to improve speed and precision of data analysis. There is an urgent need to break down the barriers that exist by giving a genomic data compression solution which considers the entire genomic data workflow. Currently, no compression solution adresses the entire dataflow. Such a technology is a new challenge. Thanks to artificial intelligent value smoothing technology, ENANCIO aims to bring the only one technology improving the entire value chain of the genomic data, from the improvement of the compression rate and compression time, allowing a faster e-transfer and a lighter storage, to the improvement of the time and precision of analysis. Genomic data market has shown a fast raise and will reach 2 billion € in 2025. ENANCIO addresses two categories of customers, private and academic sequencing platforms who manage thousands giga bytes of data. During ORIGAMI project, ENANCIO aims to study the feasibility of the algorithm to fit with the latest sequencers on the market, NovaSeq platform from Illumina (90% of market share). This new platform will be the standard of tomorrow, justifying the need of compatibility with LENA algorithm.

Keywords: new generation sequencing,sequencing technology,data compression
The aroma/flavor profiles of Freekeh, a Mediterranean green durum wheat product, its market acceptability and utilization of its production methods for other Nordic-based cereals (AnaFree)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Denmark
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-08-01
End date: 2023-07-31
Duration (months): 24.0
Total project cost (EUR): 219312.0
EU funding (EUR): 219312.0
Participants: 1
Project status: SIGNED

Analysis of Freekeh Aroma, Sensory-perception and Preparation Methods Freekeh (Arabic, ‘rubbed’) is an ancient wheat product with a unique preparation method and flavor profile. It is essentially immature durum wheat (Triticum turgidum) grains, harvested while plants are green and the seeds are soft. The plants are stacked and then set on fire (usually in situ) to rid of stalks, awns and leaves. Bushels are then threshed, grains separated from the chaff, dried and cracked. The production process lends a smoky, complex aroma to the finished product, described as nutty, earthy and smoky. Compared to dried mature Durum Freekeh is richer in fiber, protein, sugars and Mn and has a low glycemic index. Timing of harvest determines much of the quality, since protein, fiber and antioxidants decrease while phytate levels increase in parallel to seed maturation. Additionally, sugars are converted into starch as the grains fill, making seeds that are in the milk-ripe to mid-dough-ripe stages optimal. Worldwide production is rising (>300K ton/yr), demand in western country increases and it is also used in Haute Cuisine. Although its popularity, Freekeh has not been studied for its aroma/flavor profiles. I believe this product could serve as an interesting model for both basic and applicable research that has been, to date, underrepresented in food science. I propose to: a. Investigate the aroma/flavor profiles of Freekeh (e.g. volatile compounds, sugars and organic acids). Special focus will be given to compounds imparting its smoky attributes and their precursors. b. Analyze the sensory perception of consuming Freekeh dishes and to evaluate its consumer acceptability. c. Test the production method of Freekeh by utilizing common cereals (Rye, Barley, Spelt) or by adding different smoke sources. d. Evaluating the use of Freekeh in modern cuisine.

Keywords: aroma,volatile,flavor,sugar,organic acids,wheat,plant,food,gastronomy
Ecosystem response to drought: unravelling the unexplored role of plant-soil feedback (SHIFTFEEDBACK)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Environmental Biology, Ecology and Evolution
Panel description: Ecology, biodiversity, environmental change, evolutionary biology, behavioural ecology, microbial ecology, marine biology, ecophysiology, theoretical developments and modelling
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Drought is severely threatening our ecosystems and their functioning: it causes strong shifts in plant community composition that are difficult to revert. Positive feedbacks often underlie these dramatic shifts, but in many ecosystems drought causes fast-growing species to increase. These species are not only vulnerable to drought, but they also suffer negative plant-soil feedback, i.e. they change the soil microbial community in a way that keeps their own abundance in check. Thus, drought-induced shifts in plant communities do not result from positive feedbacks, unless drought changes plant-soil feedback. We know that plant-soil feedback drives plant community succession, but its role in community response to drought has never been explored. Here, I will unravel whether and how changes in plant-soil feedback underlie strong shifts in plant community composition following drought. This knowledge is crucial for mitigating the effects of drought on terrestrial ecosystems. My objectives are: 1. Examining how drought affects plant community and soil microbial community composition and the implications for plant-soil feedback 2. Quantifying the effects of plant-plant and plant-microbial interactions on plant growth and subsequent shifts in plant community composition in response to drought 3. Disentangling the mechanisms underlying drought-induced changes in plant-soil feedback I will address these objectives in a novel set of approaches. I will identify general patterns in plant-soil feedback across European drought experiments, and assess the role of plant-plant and plant-microbial interactions across a Dutch secondary successional gradient. In a set of targeted mesocosm experiments, I will elucidate the mechanisms underlying changes in plant-soil feedback and the consequences for plant community composition. These approaches will result in a step-change in understanding the dynamics of plant-soil interactions under drought and the consequences for ecosystem change.

Keywords: climate change,bacterial community,fungal community,aboveground belowground interactions,soil ecology,grassland,heathland
Light driven hybrid nanocrystal TMDC capacitors (Light-DYNAMO)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Italy
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-01-01
End date: 2025-12-31
Duration (months): 72.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Sunlight is an intermittent energy source coupled to the availability of the sun. Light-DYNAMO aims for an innovative solution to directly store the solar energy. The challenge is to implement solution-processable light-driven nanocrystal capacitors (NCCs), such as doped metal oxides. They show high charge-storage capacity accumulating multiple delocalized electrons after light absorption. This was to date shown in solution only with the additional drawback of reducing the hole with a sacrificial hole scavenger. The innovative aspect of Light-DYNAMO is to use 2D transition metal dichalcogenides (2D TMDCs), such as MoS2 or WS2, as efficient hole acceptors in a solid state structure. The sensitivity of the TMDCs’ spatial electronic landscape to the local environment (i.e. strain, defects or doping) serves as driving force for energetically driven hole relocation within the TMDC. The electrons instead remain in the NCCs. This results in long-lasting and efficient charge separation and opens novel design principles. In optimized device structures, such stored carriers are extracted. The working principle of the suggested NC/TMDC hybrid device is based on several challenges: first, the absorption and charge storage capacity of the NCCs will be enhanced by exploring novel materials. Second, the TMDC’s sensitivity to the surrounding will be extracted to a high level of control over the 2D energy level distribution. Third, the intentional design of the energy landscape (e.g. through strain manipulation) in the optimized hybrid geometry will be introduced to control carrier redistribution after charge transfer within the TMDC. Finally, appropriate devices for carrier extraction will be structured. The proposal embarks on a pioneering study by the PI on optical control over carrier density in NCC/TMDC hybrids, advancing such novel systems to a level in which the incoming sunlight is harnessed, converted, stored as charges and released on demand to power an electric circuit.

Keywords: doped metal oxides,photodoping,transition metal dichalcogenides,layered two dimensional materials,hybrid nanostructures,charge transfer,light energy storage