Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Responses of European Forests to Global Change: Building synergies among flagship manipulation experiments through a network of next generation scientists (FutureForests)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: United Kingdom,Italy,Switzerland,Germany,Estonia,Greece,France,Austria
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2025-10-01
End date: 2029-09-30
Duration (months): 48.0
Total project cost (EUR): 4746744.0
EU funding (EUR): 4746744.0
Participants: 23
Project status: SIGNED

ForesForests are at the forefront of our efforts to mitigate climate change and achieve ambitious goals within the European Green Deal. However, forests are particularly threatened by global change factors such as increasing frequency and severity of climate extremes (e.g., soil drought, heat, high evaporative demand), fires as well as increasing atmospheric carbon dioxide and nitrogen pollutants deposition. The severity, frequency, duration, and spatial extent of these global change factors is predicted to increase in future. Understanding forest responses to global change require field-sale manipulation experiments and in Europe a diversity of flagship facilities simulating global change scenarios exists. FUTUREFOREST aims to train 15 next generation scientists in assessing the impacts of global change on European forests utilising this unique network of European flagship field facilities covering the dominant forest types and regions (dry, temperate and boreal). The proposed doctoral programme embeds these facilities for addressing emerging research questions and engages 10 beneficiaries and 10 associated partners for delivering an interdisciplinary, integrated and transferable career skills programmed. Individual projects focus on assessing responses of tree processes, soil processes, biodiversity and vulnerability to pest and diseases as well modelling of forest responses to climate extremes and fire risk reduction, thus connecting 20 diverse partners with students. FutureForests combines excellent trainings, diverse supervisions and international mobility for impactful research to benefit society and the economy and to inform forest policies under the EU Green Deal and international climate mitigation efforts (Paris Climate Agreement). FutureForests is timely and connects key facilities for the first time under a doctoral programme to provide next generation scientists with skills and knowledge “most wanted” in academic and non-academic employability sectors.
Plasma Exascale-Performance Simulations CoE - Pushing flagship plasma simulations codes to tackle exascale-enabled Grand Challenges via performance optimisation and codesign (Plasma-PEPSC)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: European High Performance Computing
Action type: Research and Innovation actions
Partnership: EUROHPC (JU-JTI)
Countries involved: Sweden,Germany,Czechia,Greece,France,Spain,Finland,Slovenia
Call: Centres of Excellence preparing applications in the Exascale era (HORIZON-EUROHPC-JU-2021-COE-01, 2021)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 7919658.75
EU funding (EUR): 3957329.0
Participants: 10
Project status: SIGNED

Plasma science has been at the forefront of HPC for several decades, driving and at the same time benefiting greatly from innovative hardware and software developments. The overall goal of Plasma-PEPSC is to take this development to the next level, enabling scientific breakthroughs in plasma science Grand Challenges through exascale computing and extreme-scale data analytics. Specifically, we aim to enable unprecedented simulations on current pre-exascale and future exascale platforms in Europe to control plasma-material interfaces, optimize magnetically confined fusion plasmas, design next-generation plasma accelerators and predict space plasma dynamics in the Earth’s magnetosphere. We achieve these goals by maximizing the parallel performance and efficiency of four European flagship plasma codes with a large user base: BIT, GENE, PIConGPU, and Vlasiator. Here, we will build on algorithmic advances (regarding load balancing, resilience, and data compression) as well as on programming model and library developments (MPI, accelerator and data movement APIs and runtimes, in-situ data analysis). We ensure an integrated HPC software engineering approach for deploying, verifying, and validating extreme-scale kinetic plasma simulations that can serve as a community standard. We will establish a continuous and integrated co-design methodology to provide/receive direct input to/from the design and development of the EPI Processor and accelerator, will exploit synergies through collaborations with other CoEs, EuroHPC, and Competence Centers for cross-fertilization, adoption and full exploitation of the Plasma-PEPSC codes. Plasma-PEPSC brings together an exceptional, interdisciplinary group of highly-recognized leading scientists from academia, research centres, and HPC centres, with decades of experience in algorithmic and method developments, extreme-scale plasma simulations, and application optimizations with high involvement in strategic EuroHPC projects and initiatives.

Keywords: flagship plasma simulations,exascale,extreme scale,extreme data,heterogeneous systems,co design,epi
Politics, Institutions, and Production Networks (PINPOINT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1476023.0
EU funding (EUR): 1476023.0
Participants: 2
Project status: SIGNED

What are the political sources and consequences of economic globalization, and how do political institutions shape globalization? Current frameworks for understanding the politics over economic globalization emphasize a fragmentation of politics: political conflict breaks down to individual firms and citizens, because the gains from trade are concentrated on large, globally engaged, and politically active firms. Departing from this view, PINPOINT develops an innovative framework built on the linkages between firms created by domestic production networks. Production ties imply a much broader impact of economic globalization, because many domestic firms interact with international markets indirectly as suppliers and as customers of globally engaged firms. Moreover, these linkages vary in quantity and quality. To date, we know surprisingly little about the role of production networks in politics, which creates a mismatch between the structure of modern economies and current theoretical frameworks. Ignoring such ties risks misattributing the impact of economic globalization, overlooking economic roots of political coalitions, and misunderstanding the sources and consequences of economic globalization. PINPOINT places economic exchange between firms front and center in an account of the behavior of governments, firms, and citizens in the context of international markets, and of the role of institutions in such an account. PINPOINT will provide theoretical and empirical innovations that lead to a revised understanding of the political underpinnings of economic globalization and of the mechanisms through which institutions shape economic globalization.

Keywords: production networks,trade policy,political institutions,firms,firm heterogeneity,international trade,electoral systems,trade liberalization,political economy,political coalitions,globalization
GEM-SEE-Achro: Genomic Exploration—Mapping the Spread, Evolution, and Adaptation of an Emerging bacterial pathogen—Achromobacter (GEM-SEE-Achro)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Lithuania
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-10-01
End date: 2026-09-30
Duration (months): 24.0
Total project cost (EUR): 158597.76
EU funding (EUR): 158597.76
Participants: 1
Project status: SIGNED

Achromobacter species are rapidly emerging Gram-negative opportunistic bacteria intrinsically resistant to several antibiotics and are often the cause of healthcare-associated infections, especially in individuals with compromised immune systems or underlying conditions. Following years of misclassification of Achromobacter spp. isolates combined with complicated species typing, the understanding of the ecology of Achromobacter spp. and their clinical significance is lacking. GEM-SEE-Achro aims to answer the questions regarding the population structure, evolution, adaptation, antibiotic resistance development, and genetic variability of Achromobacter spp. both globally and locally, providing crucial insights into the factors contributing to their prevalence, antimicrobial resistance patterns and potential novel therapy approaches. Analysis of whole genome sequencing (WGS) data allows to disentangle these questions. Therefore, I propose the largest Achromobacter spp. study to date including over 800 WGS encompassing its global diversity sampled from both the environment and infected patients. Employment of a number of bioinformatics analysis methods—gene content difference analysis; single nucleotide variant and mobile genomic element identification and association with population structure; evolutionary and migration rates analysis using Bayesian phylogenetics; and resistance phenotype association with genomic differences—will help to answer the fundamental questions of how these bacteria evolve and adapt to their environment, what are the main differences in genetic composition between the environmental and clinical samples, and how these differences can inform us about the population structure and antibiotic resistance development in Achromobacter spp. The gained knowledge could be generalised and applied to studies of other less studied bacterial pathogens.

Keywords: bacteria,evolution,adaptation,genomics,whole genome sequencing,antibiotic resistance,emerging pathogens,cystic fibrosis,opportunistic bacteria,computational biology,health care research
INdium PHOsphide-based advanced Monolithically integrated photonic building-blocks at near and mid-InfraRed wavelengths (INPHOMIR)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Research and Innovation actions
Partnership: Photonics (co-programmed)
Countries involved: Italy,Netherlands,Germany,Ireland,Bulgaria,Belgium
Call: Pervasive photonics - multi-technology integration for digital infrastructure, sensors and internet of things (Photonics partnership)(RIA) (HORIZON-CL4-2023-DIGITAL-EMERGING-01, 2023)
Start date: 2023-12-01
End date: 2027-05-31
Duration (months): 42.0
Total project cost (EUR): 4999637.5
EU funding (EUR): 4999637.5
Participants: 9
Project status: SIGNED

Innovative ground-breaking technologies such as nano-satellite-based space navigation and autonomous navigation are currently hindered by the lack of compact, efficient sensing devices. The adoption of photonic integrated circuits (PICs) for these applications has been restrained by the difficulty of integrating complete photonic sensors without optical interface within the same chip. The aim of INPHOMIR project is to provide a competitive and independent European supply chain of monolithic PIC building-blocks, operating at near and mid-infrared wavelengths, by proposing the Indium Phosphide platform as a valid solution for a technological scale-up. The scientific activities will involve the validation of PICs with new ultralow loss waveguides and new mid-infrared active devices; and the first demonstration of advanced building blocks such as: extremely-high quality factor resonators at telecom (exploring optical loss compensation and slow light effect in photonic crystals), Hertz-level narrow-linewidth quantum cascade lasers and ultra-low-power sensitive heterodyne detectors at mid-infrared wavelengths. These advanced components will be employed to realise for the first time an integrated optical gyroscope and a dual-band mid-infrared FMCW lidar. These two novel sensors will be put together onto a multi-chip module board to validate a novel multi-sensorial unit with unique ranging and inertial sensing capabilities, to be exploited for aerospace missions of low-earth-orbit nano-satellites and self-driving drones. Thus, a consortium has been established, constituted by academic and industrial partners, to provide the necessary expertise and synergy in front-end (design, microfabrication) and back-end (packaging, test, sensor fusion) research activities as well as specifications definition and technological validation/exploitation of the developed use-cases. The proposed multi-sensor module will boost miniaturised and advanced technologies in leading EU industries.

Keywords: indium phosphide,photonic crystals,optical amplifiers,quantum cascade lasers,quantum cascade detectors,optical gyroscope,fmcw lidar,inertial sensing,data fusion,sensor fusion
Resilient Agricultural IrrigatioN systems for water Scarcity in Europe (RAINS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Land, ocean and water for climate action
Action type: Innovation actions
Countries involved: Spain,Greece,Netherlands,Italy,Belgium,Cyprus
Call: Improving irrigation practices and technologies in agriculture (HORIZON-CL6-2024-CLIMATE-01, 2024)
Start date: 2024-11-01
End date: 2028-10-31
Duration (months): 48.0
Total project cost (EUR): 5514044.72
EU funding (EUR): 4873758.43
Participants: 17
Project status: SIGNED

In the last years, extreme weather patterns of water scarcity (droughts) and water abundance (floods, rapid showers) are becoming more frequent and prolonged in the EU. If we do not remedy this situation, by 2050 water scarcity will lead to €12,2 billion losses per year and affect 17% of EU population. RAINS will contribute to improve the resilience of EU agriculture to water scarcity by demonstrating 10 solutions (irrigation practices, technologies and tools) that will increase the efficiency of water and nutrient management in agriculture and reduce the impact of extreme weather events. RAINS solutions include alternative forms of water supply, combined use of water and biofertilisers, improved soil water-retention, water-N/P modelling and some smart solutions (Optifangs-IA, WaterIQ) to contribute to decision-making and to integrated irrigation management across farm systems. Solutions will be demonstrated at 10 demo-farm systems representing agroecology, organic production, conventional, intensive and urban agriculture, replicated in Greece and Spain. We will also develop a hydrological and N/P model to optimised agriculture production at catchment level. A well, we will conduct co-creation workshops, knowledge transfer activities and create materials such as guidelines (2), White Papers (2) and Practice Abstracts (40). Policy focused sessions will deliver 3 sets of policy and incentives recommendations, engaging quadruple helix agricultural stakeholders, to pave the way for the uptake of sustainable irrigation and fertilization management solutions in practice in the EU. In the long term, RAINS will contribute to improve water efficiency by 50% in 12,700 ha. in more than 20 EU regions, and support >500 farmers in the transition to a more sustainable irrigation. And by 2050, the implementation of the RAINS project will save up to €6.1 billion, 244.348 million litres of water and 35.4 t CO2 eq. avoided emissions.

Keywords: water scarcity,drought,water abundance,floods,irrigation,water management,biowaste,agriculture,farming systems,water technologies,digitalization,solid water,reclaimed wastewater
Development of a predictive quantum simulation protocol for understanding DNA polymerase function and toxic inhibition (DNACopyComp)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Hungary
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-01
End date: 2027-12-31
Duration (months): 24.0
Total project cost (EUR): 182743.92
EU funding (EUR): 182743.92
Participants: 1
Project status: SIGNED

The phosphate chemistry of nucleoside triphosphates (NTPs) is at the heart of crucial biological processes including the cell’s energy storage, signalling and copying genetic information. Computational modelling valuably expands the spatiotemporal resolution of experimental structural biology, providing a key contribution to the synergistic understanding of such complex processes. However, our preliminary results on phosphatase reactions shed light on the qualitative inaccuracy of the state-of-the-art methodology capable of free energy bio-simulations. Thus, the candidate will be trained to extend the host’s uniquely accurate and efficient electronic structure approaches to the scale of enzyme simulations, producing thermodynamic properties comparable to experiments. The candidate brings complementary computational biochemistry experience and reaction mechanistic knowledge to this collaboration, demonstrated in his successful computational-experimental phosphate catalytic enzyme studies. Our concerted developments will combine methods from the forefront of quantum chemistry, high-performance computing, rare event molecular dynamics, and biochemical modelling into a widely applicable open-access protocol, with a predictive power currently limited to main-group homogeneous catalysis modelling. The reliability of the reaction mechanisms predicted by the developed method will be validated against kinetic experiments on wild-type and mutant Ras GTPases, connected to ca. one third of the cancer cell lines. Then, we will utilise the established protocol to understand the (regular and faulty) binding and incorporation of deoxy-NTPs and nucleoside analogue drugs during mitochondrial DNA polymerisation to a yet unknown atomistic detail. These results will provide a foundation for a comprehensive kinetic model for DNA polymerase fidelity and for the future rational optimisation of more selective and less toxic antiretrovirals.

Keywords: computational modelling of enzyme catalysis
Stable and Clean Iron Power from ICONIC (ICONIC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2023-09-01
End date: 2025-02-28
Duration (months): 18.0
Total project cost (EUR): 191571.43
EU funding (EUR): 150000.0
Participants: 2
Project status: CLOSED

Iron Power is a new technology to store and transport sustainable energy. An iron aerosol mixture is burned in a flame and the heat is used in high temperature processes. The formed iron-oxide powder is collected and transported to places with a surplus of green hydrogen, where it is regenerated back to iron powder. As such, Iron Power is a very promising CO2-free circular energy carrier of sustainable energy, which has a very high energy density, is easy to handle, safe, environmentally friendly and cheap. Within the fast growing Iron Power community, existing solid fuel combustion concepts are applied mostly, but these show severe problems caused by the specific character of iron aerosol flames: a) flame stabilisation is difficult to establish, b) nano-particles and c) high NOx emissions are also difficult to circumvent. A completely new combustion concept is needed to solve the problems. The ERC program MetalFuel creates the basic knowledge on metal aerosol combustion with the right ingredients to do solve these problems. The combustion concept developed is called ICONIC (Ignition COntrolled low-Nox Iron Combustion). Within this ERC PoC a well-controllable ICONIC burner will be developed, designed, tested and patented. A small-scale system will be developed and studied first, after which a conceptual design of Mega-Watt size will be developed which will enable future implementation in an industrial-scale system. Furthermore, the possible future market will be evaluated. A start-up is already interested and a launching customer seems to be in view, if the PoC is successful.
Made-to-measure micromachining with laser beams tailored in amplitude and phase (METAMORPHA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Photonics, Made in Europe (co-programmed)
Countries involved: Germany,Belgium,Spain,Luxembourg,Netherlands,France,Greece
Call: Laser-based technologies for green manufacturing (Photonics - Made in Europe Partnerships) (RIA) (HORIZON-CL4-2021-TWIN-TRANSITION-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 6994297.5
EU funding (EUR): 6994296.0
Participants: 12
Project status: SIGNED

The METAMORPHA concept is a single agile USP laser micromachining platform to replace many conventional manufacturing process chains. It has the potential to eliminate thousands of environmentally damaging production processes. METAMORPHA is all-electric, all-digital, produces no waste chemicals and enables novel processes for product rework and repair. All-in-one module: The key to this agility is a combination of two cascaded spatial light modulators (SLM) and a galvo scanner resulting in the most sophisticated beam shaping and steering ever developed. This allows a single module to perform the job of several laser processing heads: e.g. polishing, milling, drilling and cutting (importantly including any wall angle). Made-to-measure laser processes: Each infeed component is scanned with a high resolution 3D sensor. A machine learning algorithm determines an individualised laser process to maximise efficiency and ensure "first time right". In-line process control: Data from additional online sensors are processed using an edge device running a self-learning algorithm to provide real-time feedback for system control. The ultra-fast edge-based signal processing and synchronisation are key project topics. Agile and scalable: Suitable for any standard industrial production line including 2-, 3- or 5-axis, rotating and roll-to-roll, and for scale up to parallel processing with multiple modules. The three end use cases (UCs) show the versatility and scope for replacing existing process chains: UC-1 PHILIPS: Small complex metal parts (shaving heads) requiring 90 degree wall angles. UC-2 TKSE: Large area embossing rollers and the re-writing of old rollers. UC-3 CERAT: Very hard carbide parts and refurbishment of worn parts. Sustainability assessment: A life cycle analysis (LCA) and social LCA will be carried out to quantify the environmental and socioeconomic benefits. A detailed plan for exploitation and an extensive dissemination and communication plan are in place.

Keywords: laser micromachining beam tailoring