Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Spatial machine-learning analysis of child indicators (SMALACI)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands,United States
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-02-01
End date: 2026-01-31
Duration (months): 24.0
Total project cost (EUR): 203464.32
EU funding (EUR): 203464.32
Participants: 2
Project status: SIGNED

Horizon Europe seeks to achieve the UN’s Sustainable Development Goals (SDGs). The WHO–UNICEF–Lancet Commission suggests placing children at the center of the SDGs, because children are among the world’s most vulnerable and marginalized population. Child indicators calculated with surveys are limited because surveys can be outdated and do not cover all the regions of a country. In this context, the objective of the project is to develop a methodology to overcome this limitation and identify vulnerable young children in countries with outdated, incomplete, and low-quality survey information. The methodology is based on a spatial machine-learning analysis of child indicators and integrates 3 disciplines: child development, spatial analysis of satellite images, and machine-learning. Satellite images and households’ simulations will complement the missing or outdated information of surveys, and machine learning will identify children that could be left behind during the development process due to the intersectionality of gender with biological diversities, ethnicity, socio-economic status, and geographical location. The project will create new tools for monitoring the progress towards the SDGs and will help to formulate targeted interventions that increase the social impact and reduce the economic costs of poverty-reduction and development programs. If the project is funded, Dr. Rolando Gonzales Martinez will carry out the fellowship at the University of Groningen, under the supervision of Prof. Dr. Hinke Haisma and with support from Prof. Dr. Dimitris Ballas. A short visit to UNICEF is planned as a secondment for Dr. Gonzales Martinez, so he can work with UNICEF on improving the policy impact of the project. The transfer of knowledge between the research fellow and the host organization, the teaching activities, and the short visit to UNICEF will increase the career prospects and employability of Dr. Gonzales Martinez within and outside academia.

Keywords: child development spatial analysis machine learning
Ferroptosis Inhibitors For Neurodegenerative Disorders (NeuroFerro)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Belgium,Poland
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2025-03-31
Duration (months): 30.0
Total project cost (EUR): 239700.0
EU funding (EUR): 239700.0
Participants: 2
Project status: CLOSED

FERROptosis inhibitors for NEUROdegenerative disorders (NeuroFerro) will focus on the development of potent compounds with improved pharmacokinetic properties, including blood-brain barrier (BBB) permeability for future application in the treatment of neurodegenerative disorders. Ferroptosis is non-apoptotic programmed cell death that has been linked to the pathophysiological processes of many diseases, including dementia, Huntington’s disease, Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis (ALS). Neurological disorders are one of the most significant causes of disability-adjusted life-years and death worldwide with very limited treatment available. Although ferroptosis inhibitors developed by Augustyns and Vanden Berghe (supervisors) are currently best in class compounds, they suffer from no or minor BBB permeability. Therefore the main aim of the project will be the design and synthesis of novel ferroptosis inhibitors with improved pharmacokinetic parameters and high blood-brain barrier permeability to target ferroptosis in neurodegenerative disorders.

Keywords: ferroptosis,ferroptosis inhibitors,neurodegenerative disorders,lipid peroxidation,cell death
EU High Barrier Home Compostable Film Made with Waste to Substitute Market Dominant Asian Import (HOMEGROWNFILM)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 1750000.0
EU funding (EUR): 1750000.0
Participants: 1
Project status: SIGNED

With the HOMEGROWNFILM project, we aim to bring to market the first home compostable, single-layer high barrier film suitable for packaging long-life dry, moist (e.g. fresh meat), semi-liquid, as well as liquid products, thanks to its high barriers to oxygen and water vapour, making it optimal for the most demanding applications. It efficiently protects the packaged products and their organoleptic properties for one year, which is drastically more than the 2-3 weeks offered by our European competitors. Our film made with 100% EU raw materials, avoiding dependence on Asian imports: a common issue with competing materials. To avoid using Natureflex™ in our film structure, the only high barrier home compostable layer available at scale, which gives Japanese manufacturer Futamura a virtual monopoly, resulting in artificially high prices and long delivery times, we have been developing our own high barrier, home compostable film including raw materials we extract from Spanish/Mediterranean agro-industrial waste. This not only eliminates the dependence on a single supplier, but it also prevents competition between food and feedstock by introducing secondary raw materials. Avoiding Natureflex™ also eliminates its rigidity issues and allows our film to be transformed using a wider range of processes common in the industry. With this project, we will become the first mover in high barrier home compostable materials using organic waste feedstock and offering better functionality than current market standards. This project is crucial for the EU to develop strategic autonomy in sustainable packaging materials. We are now poised to launch our groundbreaking solutions to the market, initially focusing on the food industry, but also targeting other sectors (horticulture and cosmetics). Our aim is to expand beyond our current licensing model to gain increasing control over the value chain by selling our packaging materials in pellet form and developing our own biopolymers.

Keywords: home compostable materials,barrier films,waste management,raw material value chain
Thrombolytic Nanobody Therapy for Dissolving All Types of Blood Clots (TANO-TAC)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator Open 2025 (HORIZON-EIC-2025-ACCELERATOR-02, 2025)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 3570674.03
EU funding (EUR): 2499471.82
Participants: 1
Project status: SIGNED

TargED Biopharmaceuticals B.V., a spin-off from UMC Utrecht, is developing TGD001, an innovative first-in-class drug designed to treat all types of blood clots associated with thrombosis, a leading global cause of death that currently has limited effective treatments. TGD001 has shown superior results in preclinical studies, demonstrating high precision, safety, and efficacy, and TargED has raised over €45 million to fund its clinical trials, moving toward market readiness. Unlike existing therapies, TGD001 has the ability to target both von Willebrand Factor (vWF) and fibrin, addressing the varied composition of blood clots. This dual-target mechanism enables TGD001 to effectively dissolve both macrovascular and microvascular clots, making it a "one-drug-fits-all" solution for thrombotic conditions. This comprehensive approach extends the treatment window, reduces bleeding risks, and makes it suitable for a wider range of patients compared to existing therapies. TGD001 has received Orphan Drug Designation from the European Medicines Agency for thrombotic thrombocytopenic purpura (TTP), granting 10 years of market exclusivity, regulatory support, and financial incentives, significantly accelerating its development for immune Thrombotic Thrombocytopenic Purpura (iTTP), a rare and severe form of TTP. Led by an experienced team, TargED is advancing TGD001 through clinical development, targeting iTTP and Acute Ischemic Stroke (AIS), indications on opposite ends of the clot composition spectrum, with global potential peak revenues of €421 million and €5.2 billion respectively. TargED’s core strategy is to advance TGD001 through to MAA/BLA submission independently. To further support the development, TargED plans a €25M Series B funding round to execute Phase 2a trials and a 1000L GMP manufacturing run to scale production. EIC funding is crucial to bridge the funding valley of death, accelerate clinical development, and ensure timely market entry and patient access.

Keywords: thrombosis,acute ischemic stroke ais,immune thrombotic thrombocytopenic purpura ittp,von willebrand factor vwf,fibrin
Chip-scALe visiBLE-iNfrared imaGing sEnsor (CHEERS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2024-12-01
End date: 2026-11-30
Duration (months): 24.0
Total project cost (EUR): 3569146.4
EU funding (EUR): 2498402.48
Participants: 1
Project status: SIGNED

According to the World Health Organisation, road accidents are the eighth-biggest cause of death worldwide. Bad weather, dangerous road conditions, and distracted or fatigued driving account for nearly 70% of all accidents. Current Driving Monitoring Systems (DMS) and Advanced driver-assistance system (ADAS) underperform in harsh conditions, do not guarantee high standards of security and simply do not provide the needed supportive information to drivers: SWIR (Short-wave infrared) is what is missing. SWIR light, thanks to its peculiar physical properties, allows for better vision in critical visibility conditions such as fog, night, dusk and dawn. CHEERS - Chip-scALe visiBLE-iNfrared imaGing sEnsor- aims at developing a multi-spectral image sensor which, thanks to a unique patented electronic structure, is capable of selectively detecting the visible-near infrared (VIS-NIR) and SWIR regions of the electromagnetic spectrum. Being based on Si and Ge photodiodes monolithically integrated in a single device, EYE4NIR technology is fully compatible with mainstream foundry processes, harnessing their scalability and cost-efficiency to its advantage, as opposite to current SWIR imaging technologies.The robustness of our approach is proven by very promising results on lab-scale prototypes. Within CHEERS, EYE4NIR, a fabless image sensor supplier, aims at manufacturing a first HD VIS/SWIR chip ready for high-volume productions. Target market is automotive where the demand for DMS and ADAS is growing (also because of regulatory constraints) and where price makes the difference. CHEERS is effective, reliable and versatile. Being an enabling technology, it can be implemented in other application domains such as industrial automation, consumer electronics and non-invasive quality control. Semiconductors are key for Europe's competitive leadership in the era of the digital economy; EYE4NIR aims to grow and become a key fabless player in the ecosystem.

Keywords: semiconductor image sensor swir short wave infrared dms driving monitoring system adas advanced driver assistance system
High Performance Organic Narrowband Emitters for Stable Blue OLEDs (HONESTY)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Lithuania
Call: ERA Fellowships (HORIZON-WIDERA-2023-TALENTS-02, 2023)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 142757.76
EU funding (EUR): 142757.76
Participants: 1
Project status: CLOSED

Constricted by electron spin statistics, the maximum internal quantum efficiency of 100% can be achieved in organic light-emitting diodes (OLEDs) by utilizing purely organic thermally activated delayed fluorescence (TADF) materials. However, due to strong charge transfer, they exhibit broad emission with a full-width-at-half maximum (FWHM) > 70 nm. Recently, multiresonant TADF (MR-TADF) emitters, a sub-class of TADF materials based on alternating boron and nitrogen atoms embedded into polycyclic aromatic hydrocarbon scaffolds, are attracting much interest in OLEDs. Their key attributes include a narrow FWHM, high photoluminescence quantum yield, and unprecedented color purity. Even though these MR materials have advantages in color purity over conventional TADF materials, their device stability is weak and results in a poor operational lifetime (LT) due to the large singlet-triplet energy gap, delayed fluorescence lifetime, and too slow rate of reverse intersystem crossing (RISC). Especially, narrowband blue OLEDs LT (<100h) is still inferior to the conventional TADF OLEDs. The HONESTY project seeks to address the above issues by rationally designing organic narrowband novel TADF emitters. Our designs comprised four types (a combination of boron and non-boron) targeting a high RISC rate, leading to highly stable narrowband blue OLEDs with long LT. Among the four types, one design includes yet unexplored rigid tellurium-based acceptor decorated with high triplet energy donors, which is keen for new TADF scaffolds. The rigidity of all chemical components with slightly twisted confirmation and aryl groups on donors will work coherently to furnish highly stable OLEDs with suppressed efficiency roll-off, improved device stability, and long LT. Overall, the HONESTY proposal is anticipated to provide a breakthrough in stable blue narrowband TADF-OLEDs with the supervision of Karolis Kazlauskas, a physics expert in stable OLEDs working at Vilnius University, Lithuania.

Keywords: photophysics,organic light emitting diodes,narrowband materials,and boron chemistry
Cardiac Tech - Revolutionising safety in post-cardiac surgical recovery (TPSM)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 18.0
Total project cost (EUR): 1225000.0
EU funding (EUR): 1225000.0
Participants: 1
Project status: SIGNED

Improving safety in post-cardiac surgical recovery - development and testing of a Temporary Pacing Safety Monitor. Cardiac Tech has created a patented temporary pacing device, the Pace-Protect, in order to substantially improve patient outcomes post-cardiac surgery. The bedside device detects, manages and notifies of rhythm disturbances that can lead to serious complications. Its has been developed by a highly capable team that includes both cardiology and medical device specialists, supported by grant funding and venture capital. The business model focusses on use of disposable leads and we estimate the serviceable addressable market in the EU and US to be €320M annually. This proposal moves the technology from TRL 6 to TRL9 over the course of an 18-month work programme comprising 6 months of pre-clinical device development followed by a 12-month clinical pilot. The pre-clinical programme includes: • Development of the user interface • Electronics testing and compliance • Addition and validation of device algorithms • Software unit testing and system integration testing • Preparation of fully compliant labelling and instructions The clinical phase of the programme will be a pilot study with clinical partners in which we will validate Pace-Protect algorithms and device responses using in vivo electrogram (EGM) data collected from a cohort of cardiac surgery patients.

Keywords: pacemaker,medical device,cardiology
Superconducting Integrated Circuits for Scalable Quantum Systems (SuperICQ)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Finland,United Kingdom,Sweden
Call: EIC Pathfinder Open (HORIZON-EIC-2025-PATHFINDEROPEN, 2025)
Start date: 2026-03-01
End date: 2030-02-28
Duration (months): 48.0
Total project cost (EUR): 2998012.75
EU funding (EUR): 2998012.75
Participants: 4
Project status: SIGNED

Superconducting circuits based on Josephson junctions (JJs) are the cornerstone of quantum and classical cryogenic electronics, which is an active topic of research and technological development. Conventional JJs rely on electric current or magnetic flux control, which is far less practical as compared to the voltage control used in conventional field-effect transistors underpinning the modern semiconductor industry. Thus, the realisation of scalable gated JJs with local electrostatic control - Josephson field-effect transistors (JoFETs) - is expected to kick off a new era in quantum computing hardware and ultra-fast and low-power computing in the fields of artificial intelligence (AI) and high-performance computing (HPC). Moreover, JoFET technology can provide ultra-low-power superconducting integrated circuits (ICs) for qubit control and readout, unachievable by conventional silicon electronics, to support and enable the ongoing quantum computing revolution. Despite the proof-of-concept demonstrators of JoFETs in various material platforms, reported since the 1980s, the technology has not advanced to the IC level. Empowered by the unique scalable fabrication process for graphene-based JoFETs recently demonstrated by SuperICQ members, we will develop a 200 mm wafer platform for truly scalable superconducting JoFET integrated circuits. With our platform, individual modules will be developed, such as quantum-limited parametric amplifiers, on-chip filters, ultra-sensitive microwave bolometers, voltage-tunable resonators, and multiplexed control and readout modules for scalable interfacing of superconducting qubits. We will validate the developed JoFET ICs by using them for the control and readout of state-of-the-art superconducting qubits. Our project’s ultimate goal is to demonstrate a novel path toward ultra-low-power electronics for scalable control, readout, and interfacing of superconducting quantum computers and advance toward future quantum systems-on-a-chip.

Keywords: jofet,200 mm wafer scale,graphene,superconducting integrated circuit,ultra low power,gated josephson junctions,scalable qubit control and readout,quantum system on a chip
Female Flourishing and the Economic Frontier (FEMFRONTIER)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance , management
Countries involved: United Kingdom
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2025-12-01
End date: 2030-11-30
Duration (months): 60.0
Total project cost (EUR): 2482322.0
EU funding (EUR): 2482322.0
Participants: 1
Project status: SIGNED

Women’s economic flourishing is not only an equity concern: growing evidence shows significant efficiency gains from women entering male-dominated fields and collaborating with male colleagues. However, there is little work on the process through which these gains towards the efficient frontier can be realized, and how the benefits can be shared by all. This proposal, comprised of 7 projects, will shed light on how to spur inter-gender collaboration and trust, through 3 distinct channels: 1) Interpersonal skills, 2) Community-based career paths and role models and 3) Institutional support and protection. On interpersonal skills, I will study the long-term effects of negotiation skills training on professional and educational outcomes for women in Zambia, as well as partner with the Italian Ministry of Education to research how these skills enable collaboration in middle school coding clubs. On community career paths, I will collaborate with the Zambian Ministries of Education and Health to investigate whether professionalized community health workers inspire girls in rural areas to pursue further education and enter male dominated fields. On institutional support, I will work with the Small Claims Court in Zambia to research whether contract-enforcing institutions spur collaboration between male and female entrepreneurs and improve business outcomes. This proposal makes four novel contributions to the literature. First, it focuses on how to resolve frictions in inter-gender collaboration beyond the household, to create economic gains while protecting the more vulnerable partner. Second, it exploits novel panel data and RCT interventions to study long-term impacts of empowerment interventions. Third, it looks at how interventions affect welfare outcomes and expand the economic frontier by measuring spillovers on men, communities, and marketplaces. Fourth, it explores collaboration throughout a woman’s life-cycle, comparing returns of early and later investment.

Keywords: gender