Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Integrated Technological and Information Platform for wildfire Management (SILVANUS)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: Innovation actions
Countries involved: Italy,Indonesia,Spain,Ireland,Italy,Italy,Italy,Italy,Australia,Germany,Italy,Italy,Italy,Cyprus,Romania,Romania,Slovakia,Greece,Greece,Greece,Croatia,Poland,Slovakia,Sweden,Greece,Croatia,Poland,Sweden,France,France,Czechia,Brazil,Luxembourg,Portugal,Portugal,Portugal
Call: Preventing and fighting extreme wildfires with the integration and demonstration of innovative means (H2020-LC-GD-2020-3, 2020)
Start date: 2021-10-01
End date: 2025-03-31
Duration (months): 42.0
Total project cost (EUR): 24199862.87
EU funding (EUR): 19902190.26
Participants: 54
Project status: SIGNED

SILVANUS envisages to deliver an environmentally sustainable and climate resilient forest management platform through innovative capabilities to prevent and combat against the ignition and spread of forest fires. The platform will cater to the demands of efficient resource utilisation and provide protection against threats of wildfires encountered globally. The project will establish synergies between (i) environmental; (ii) technology and (iii) social science experts for enhancing the ability of regional and national authorities to monitor forest resources, evaluate biodiversity, generate more accurate fire risk indicators and promote safety regulations among citizens through awareness campaigns. The novelty of SILVANUS lies in the development and integration of advanced semantic technologies to systematically formalise the knowledge of forest administration and resource utilisation. Additionally, the platform will integrate a big-data processing framework capable of analysing heterogeneous data sources including earth observation resources, climate models and weather data, continuous on-board computation of multi-spectral video streams. Also, the project integrates a series of sensor and actuator technologies using innovative wireless communication infrastructure through the coordination of aerial vehicles and ground robots. The technological platform will be complemented with the integration of resilience models, and the results of environmental and ecological studies carried out for the assessment of fire risk indicators based on continuous surveys of forest regions. The surveys are designed to take into consideration the expertise and experience of frontline fire fighter organisations who collectively provide support for 47,504x104 sq. meters of forest area within Europe and across international communities. The project innovation will be validated through 11 pilot demonstrations across Europe and internationally using a two sprint cycle.

Keywords: forest landscape management,3d forest model,citizen engagement,power and waer utilities,regulation and insurance,big data framework
Scientific Excellence in Animal Reproductive Medicine and Embryo Technology (SEARMET)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Estonia,Denmark,United Kingdom
Call: Twinning (H2020-TWINN-2015, 2015)
Start date: 2016-01-01
End date: 2018-12-31
Duration (months): 36.0
Total project cost (EUR): 1001250.0
EU funding (EUR): 1001250.0
Participants: 4
Project status: CLOSED

The aim of the SEARMET project is to improve the scientific knowledge and innovation capacity of the Estonian University of Life Sciences (EMU) in the linked fields of animal reproductive medicine and embryo technology. This will be done by strengthening collaboration with two high-ranking foreign academic institutions: Sheffield University (USFD), a leading university in the field of reproductive physiology and in the gametes and embryo maternal interaction and Copenhagen University (UCPH), which is a model of excellence in the in vitro production (IVP) of bovine embryos and in induced pluripotent stem cells (iPSC) research. Furthermore, in order to achieve scientific excellence in animal reproductive medicine, EMU must also work to make stronger linkages with human reproductive research. For this reason, EMU’s long-time collaborator within Estonia, the University of Tartu (UTARTU) will participate as a 4th partner. Due to their high level of competence in making this link, both USFD and UCPH will serve as mentors in this process as well. In addition to building bridges to human reproductive research, EMU will increase its research excellence by improving staff expertise, expanding its network of potential scientific partners and building the overall capacity of the organization so that it can become a leader in the field. By doing so, EMU will achieve a greater impact in both the scientific community and in society by reaching out to key stakeholders such as industrial actors so as to exploit the results of research.

Keywords: animal reproductive medicine,embryo technology
Political knowledge as teamwork: The Academy of Zamość print shop (1594-1627) (PrinTeam)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Poland
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-07-01
End date: 2018-06-30
Duration (months): 24.0
Total project cost (EUR): 146462.4
EU funding (EUR): 146462.4
Participants: 1
Project status: CLOSED

This research project investigates the collective effort behind the development of modern political science through a case study unique in Europe: the editorial activity of the Academy of Zamość. This academy was one of the most distinguished schools of the early modern era and its primary mission was to train the Polish nobility for political life. It also had its own print shop where teachers jointly collaborated in the preparation of texts for printing. My analysis will consider the period from the foundation of the Academy in 1594 up to the destruction of the printworks by fire in 1627, during which time policy was largely influenced by its founder, the political and military leader Jan Zamoyski (1542-1605). To avoid misinterpretations common to mono-disciplinary approaches, I will adopt an inter/multidisciplinary method, integrating the history of political thought, of ideas and of printing. I will also employ interpretative tools of the sociology of knowledge which have never before been applied to the cultural life of a Renaissance academy. I will use this innovative method to explore: 1. the Zamość publications and the academic curricula of their creators; 2. the political issues most frequently addressed in the publications, and their relation to the teaching activities; 3. the interactions between the various working groups and individuals in the print shop. My project is the first to produce a wide-ranging analysis of a fundamental topic in the history of early modern culture, since this Academy predated by several decades similar experiences elsewhere. This proposal also meets the Work Programme training objectives in the acquisition of new (transferable) skills and a considerable enhancement of professional maturity. Finally, my research will be widely disseminated, delivering a monograph, online research tools, articles, and presentations in Poland and abroad, contributing to raise awareness about the collective production of knowledge among scholars.

Keywords: early modern political thought,publishing,collective knowledge production,academy of zamo,statecraft
Shaping Smarter Consumer Behaviour and Food Choice (FoodSMART)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria,Greece,Greece,France,Denmark,United Kingdom
Call: Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) (H2020-MSCA-RISE-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 499500.0
EU funding (EUR): 499500.0
Participants: 6
Project status: CLOSED

Compared to meals prepared at home, meals eaten out tend to contain more calories, total fat and saturated fat and it is here where the consumer has very little control or knowledge of the nutrient profile of the food they are eating (Bohm and Quartuccio, 2008). The positive association between the rise in consumption of food prepared outside the home and the increasing prevalence of obesity has been described as a major health and wellbeing societal challenge. Attempts to increase public awareness of appropriate ways to eat more healthily unfortunately do not seem to have led to significant changes in patterns of food purchase and consumption especially from an eating ‘out-of-home’ situation. It has become obvious that the development of effective measures for improvement requires further systematic research and a radical approach. The aim of FoodSMART is to develop an innovative technical (ICT) menu solution that enables informed consumer choice when eating out that takes into account individual characteristics (such as culture, dietary requirements and age group) as well as product (specification) and environmental cues (choice architecture and consumption setting). This aim will be achieved through the evaluation of consumer orientated intelligence (what information consumers require/trust i.e. information quality); the assessment of industry orientated intelligence (impact of customisation) and the subsequent development of data analytics and Quick Recognition (QR) coding for personalised food recommendation; thereby, facilitating the consumption of healthy and appropriate dishes. Results will be gathered and modelled to provide strategic intelligence for menu design and decision-making (by Industry) and for policy purposes (by the EU); further, this translational research will be disseminated both at scientific and consumer levels. Increasing the pace and scale of innovation within out-of-home eating is fundamental to this proposal.

Keywords: out of home eating,health,diet,sustainable food choice,consumer behaviour
Novel technology for industrial Pressing, Washing and Drying in manufacturing of specialty compounds (PWD)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-06-01
End date: 2022-11-30
Duration (months): 42.0
Total project cost (EUR): 3499000.0
EU funding (EUR): 2449300.0
Participants: 1
Project status: CLOSED

The PWD project aims at the development of an innovative and highly-advanced filter/dryer (PWD filter/dryer or the PWD solution/technology) applicable for the industrial process of filtration, separation and drying in the manufacturing of specialty compounds (such as pharmaceutical ingredients/drugs, chemical ingredients/material etc.). The PWD technology is destined to swiftly replace the obsolete and inferior state-of-the-art (the Nutsche filter/dryer technology) and in the process to create significant value for its users by substantially increasing their operational productivity, flexibility and elasticity. The initial application targets pharmaceutical and chemical industries where we have already started receiving recognition and created commercial interest from two large multinational corporations (BAYER – the 5th largest pharmaceutical manufacturer in the world; Lanxess – the leading specialty chemicals company). The PWD project that is expected to last 24 months will allow us to replicate, on the industrial/commercial level, the highly encouraging results we have achieved with the PWD filter/dryer prototype. Moreover, the project will also allow us to create awareness of the PWD technology among key stakeholders and potential clients/users allowing for a swift commercial exploitation of the PWD project results within 3-6 months from the completion of the project.

Keywords: industrial nano processes,filtration,washing and drying,pharma and chemical compounds,nutsche technology,reduction of energy,ghg reduction,reduction of solvents,decrease pollution
BusUp: Multi-platform On-demand Crowdsourced Bus Transportation for Smart City Mobility (BUSUP)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: SME instrument
Countries involved: Spain
Call: Small business innovation research for Transport and Smart Cities Mobility (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2017-03-01
End date: 2018-12-31
Duration (months): 22.0
Total project cost (EUR): 1407914.0
EU funding (EUR): 985539.8
Participants: 1
Project status: CLOSED

BusUp is an innovative concept in smart mobility that allows travelers to book on-demand crowd-sourced buses for leisure and commuting. Users are able to setup their own routes in the web-platform and app. They can share them with their friends and colleagues, or can make them public on the platform or social media for anybody join. BusUp is also available for B2B clients that want to create their own routes through a dedicated web platform. BusUp was created to solve a need in medium-distance travel: commuting in suburban and exurban areas, or traveling to events like music festivals and sports events located in city peripheries or neighboring towns - essentially anywhere public transport is limited or non-existent, and where the car is the only option despite the fact that it’s more expensive, less sustainable, or simply no fun. While on-demand bus transportation solutions are already growing in the United States and India, they are only now starting to emerge in the EU, and are limited by their technology and business models. By employing proprietary artificial intelligent algorithms that determines optimal pick-up times, locations and vehicle routes, in combination with crowd-sourced payment modules, BusUp is able to offer one of the most innovative solutions in collective road transportation. By using BusUp users will be contributing to the reduction of congestion and pollution, while joining a community of like-minded travelers who want to enjoy the ride. Our current platform, BusUp 1.0, has been extensively tested with local bus operators and passengers in Barcelona for over 4 months and has already started to serve its first paying customers. BusUp has already reached a commercial agreement to internationalize and to operate in Sao Paulo (Brazil) in 2017.

Keywords: smart mobility,on demand transportation,ride sharing,sharing economy,collective transportation,crowd sourced bus transport,commuting,event travel,charter bus,charter coach
Unraveling the Molecular Changes that Drive the Repression of the Unfolded Protein Response with Ageing (UCUPA)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

What defines the functional specialization of a cell is its unique proteome. Proteins need to be translated and properly folded to ensure their biological function. Several protein quality control pathways have arisen during evolution, some of them specialized in monitoring protein folding in specific organelles . As a result of ageing, animals lose their ability to protect their proteome, leading to the accumulation of protein aggregates and the onset of age-related disorders. The Unfolded Protein Response (UPR) of the Endoplasmic Reticulum (ER) is a central protein quality control mechanism that declines with ageing. This project will use the nematode Caenorhabditis elegans as a model to understand age-related proteostasis dysfunction. C. elegans offer many advantages over the use of vertebrate models, such as its short lifespan of about two weeks, reduced costs, and fewer ethical issues. We will focus on the UPR pathway, as changes in this pathway have already been implicated in the ageing process itself and in the onset of age-related disorders, such as Alzheimer’s disease. We propose to use CRISPR genome editing to create C. elegans transgenic reporter strains that enable us to track the activity of different UPR signalling molecules using microscopy and molecular biology techniques. We will monitor two central steps of the IRE-1/XBP-1 UPR pathway (1) the activation of the transmembrane sensor protein IRE-1 and (2) the biogenesis of the transcription factor XBP-1s. After age-related changes have been identified, we will use mutagenesis-based screening assays to screen for novel interventions that prevent UPR pathway shutdown. This research will contribute to a better understanding of why ageing occurs, as well as suggesting new therapeutic avenues for age-related disorders. This proposal will also be instrumental for the development and transference of new skills between the host and the applicant that will lead me towards independence.

Keywords: c elegans,er stress,ageing,proteostasis
Accessible, Reliable and Simple Screening of stress- and memory-related diseases (ARSS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-12-01
End date: 2019-03-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Mindmore’s digital neurocognitive screening tool Minnemera® allows patients to do evidence-based neurocognitive tests on a tablet at their local primary healthcare center. Minnemera aims at replacing the manual tests used today. They are expensive and time-consuming since and require a test-administrator and manual analysis. By making these test digitally available and self-administered, cognitive screening becMindmore’s digital neurocognitive screening tool Minnemera® lets patients do evidence-based neurocognitive tests on a tablet at their local primary healthcare centre, instead of at a specialist. With our tool, test administrators and manual analysis are not needed and clinicians can detect neurocognitive diseases earlier. The reason why Mindmore can succeed with the business innovation project is its all-female team with competences including deep Neuroscientific knowledge, excellence in Software Development with strong entrepreneurial drive and international communication abilities. The company which was founded in 2017 has attracted several grants from various funding bodies as there is a great interest in the innovation. Mindmore has established relations and cooperation within the two main market segments, health care centers and sports clubs and high schools. The goal of the project (phase 1 and 2) is to bring the Minnemera concept to international market launch and move the TRL level from 6 to 9. The goal of phase 1 is to investigate the technical, economic and financial feasibility of the innovation and get commitment from test partners for phase 2. The ARSS project will have a substantial impact in Mindmore AB’s performance. By 2023, we expect to increase our customer portfolio to around 234 clients across the EU, €3,7 M in turnover and 28 new jobs have been created. Considering the initial investment budgeted for the Phase 1 and 2, the payback time will arrive by the 4th year of commercialisation and, by 2023, our accumulated profit will be €3.83 M.

Keywords: cognitive health,early detection,democratizing specialist skills,psychometric
Unique TNFα lysine myristoylation; elucidating its function, regulation and integration into inflammation (TNFaLysMyr)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2018-09-01
End date: 2020-08-31
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Tumour Necrosis Factor-alpha (TNFa) is an important cytokine implicated in many autoimmune and inflammatory disorders, in which TNFa-blocking antibody drugs have become first line treatment. Nevertheless, clinical responses are variable. To improve and expand therapeutic strategies, a better understanding of TNFa and the many other cytokines secreted from cells is crucial. It was recently shown that TNFa is myristoylated on a lysine residue (KMyr), a unique modification that suggests an important but yet unexplored role for KMyr in cytokine biology. I will investigate the impact of KMyr on TNFa signalling, and its wider role in secretion and signalling of other cytokines, using a unique multi-disciplinary approach combining state-of-the-art chemical biology tools with molecular cell biology and proteomics. The role of KMyr in TNFa trafficking, secretion and signalling will be identified using human macrophage cell lines that produce mutant TNFa proteins with the relevant lysine residue substituted or deleted. KMyr proteins will be identified through a powerful approach that introduces a small chemical tag into the myristate in cells; this tag can be selectively functionalized to allow sensitive fluorescence imaging of KMyr within living cells, and purification for identification by mass spectrometry. The global scope of KMyr in the proteome will be analyzed in parallel, with emphasis on other secreted cytokines such as IL1alpha, which may be controlled too via KMyr. Regulation of TNF KMyr will be explored by identifying KMyr transferases and demyristoylases using chemical photo-affinity tools that can bind proteins interacting with KMyr, yielding putative targets for future first line therapies.

Keywords: chemical biology,chemical proteomics,tnfalpha tumour necrosis factor alpha,cytokine,lipidation,myristoylation,signalling,inflammation