Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Crisis, Housing and Austerity: the emergence of a new Moral Politics? (CHAMP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-04-04
End date: 2024-04-03
Duration (months): 24.0
Total project cost (EUR): 224933.76
EU funding (EUR): 224933.76
Participants: 1
Project status: SIGNED

CHAMP is a proposed training partnership between Dr Adam Standring, Professor Jonathan Davies and the Centre for Urban Research on Austerity (CURA) at De Montfort University (DMU), Leicester, UK. The rise of political values contrary to the aims of the European project is one of the great challenges of our time. The proposed Fellowship would be the first of its kind in examining the way morals construct and mediate political demands, from where moral critiques emanate and how they are legitimized. By exploring the moral foundations of critique, the Fellowship will develop novel perspectives on how European goals of social inclusion and sustainable societies can be achieved. Building on Dr Standring's work on anti- politics and Professor Davies' research on urban austerity, this project constructs an innovative interdisciplinary analytical framework. This framework is applied to a specific policy area especially suited to a moral critique - housing - in three countries producing different responses to austerity - the UK, Ireland and Portugal. As urban areas become sites of political contestation, fundamental in the implementation and resistance to austerity, broader political issues such as intergenerational justice, redistribution, solidarity, citizenship and community resilience are distilled into concrete conflicts. In delivering this project, the Fellow will benefit from De Montfort University's outstanding research training programme, and the field leading expertise of Professor Jonathan Davies and the CURA team. The project is closely aligned with the DMU strategic priority for researching 21st century urban living. It complements UN Sustainable Development goals and contributes to meeting EU Societal Challenges, especially ""Europe in a changing world: inclusive, innovative and reflective societies"". If successful, the Fellow will emerge from the programme as a fully independent scholar of international standing and as a credit to the MSCF programme.

Keywords: morals,politics,housing,crisis,discourse
Engineering the mitral valve: bioinspired control of structure and function for enhanced in vivo performance (BIOMITRAL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and processes engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Italy
Call: ERC CONSOLIDATOR GRANTS (ERC-2020-COG, 2020)
Start date: 2021-09-01
End date: 2026-08-31
Duration (months): 60.0
Total project cost (EUR): 1990530.0
EU funding (EUR): 1880506.25
Participants: 3
Project status: SIGNED

Tissue Engineered Heart Valves (TEHVs) can restore function in the pulmonary and aortic positions and have shown capacity for tissue regeneration and growth in pre-clinical models. Yet, this concept has not been extended to the Mitral Valve (MV), whose pathologies affect >25% of the valve disease patients in Europe. In this proposal, we introduce a bio-inspired design methodology and bioprocessing technology to engineer BIOMITRAL: a polymeric, stent-less, tissue engineered MV that recapitulates native structure-function. Key to our approach is the engineering of MV leaflets and chordal apparatus. In the native MV, this set of tendon-like appendages mechanically connects the leaflets to the left ventricle (LV) and allows for harmonization of the valve kinematics, coaptation and ventricle contractile dynamics. Commercial MV prostheses used for MV replacement, as well as most existing TEHVs are mounted on synthetic stents that lack of this important structure and consequently neglect this physiological mechanism. In addition, non-degradable stents cannot adapt to patient's growth, de-facto negating a key advantage in TEHVs. Our specific hypothesis is that recapitulating native leaflet structure-function and incorporating engineered chordal apparatus will lead to an engineered MV with enhanced functional and remodeling performances. To verify our hypothesis, we will: Aim 1. Characterize the structure-function of freshly isolated human valve tissue and use the derived properties to fabricate stented (control) and stentless BIOMITRAL prototypes; Aim 2. Assess prototypes mechanics and kinematics in silico via finite element modeling and in vitro in a pulse duplicator; Aim 3. Evaluate BIOMITRAL in vivo functional performance and assess remodeling in a chronic ovine model. Engineering a “living” MV with bioinspired leaflets and chordae that connect engineered leaflets with the LV is a revolutionary concept that can fundamentally transform the design of MV prostheses.

Keywords: tissue engineering heart valve,heart valve biomechanics,biomaterials
Electromobility in urban transport: a multi-dimensional innovation (socio-economic and environmental effects) (eMobilita)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Italy,Bulgaria,Slovakia,Greece
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2016, 2016)
Start date: 2017-03-01
End date: 2020-02-29
Duration (months): 36.0
Total project cost (EUR): 1525500.0
EU funding (EUR): 1525500.0
Participants: 7
Project status: CLOSED

At present, transition towards electromobility in urban transport and related companies are among the most studied industrial areas. Different EU countries implement different methodological and business approaches to investigate the possibilities for the acceleration of electromobility integration in urban transport. Studies on these approaches to be shared within the project consortium and with different stakeholders (local authorities, producers of electric vehicles and recharging stations) will provide the basis of the initiative for increasing the interest in electromobility integration in urban transport as a multi-dimensional innovation. The thin red line of electromobility practical integration passes through the sharing of innovative ideas with relevant stakeholders by carrying out field studies, in-depth interviews and electronic on-line studies. EMobilita overall objective is to study the conditions, prerequisites and incentives for electromobility integration in urban transport and elaboration of a roadmap for its development. The specific objectives are: • To explore the experience of the European countries in the integration of electromobility in urban transport and to identify good practices; • To summarize direct and indirect multi-dimensional effects (social, economic and environmental) of the introduction of electromobility in urban transport schemes; • To elaborate a roadmap with concrete measures for introducing electromobility in urban transport; • To establish a sustainable partnership between universities and businesses through staff exchange and networking activities. In order to achieve our objectives we created a network of academic and non-academic institutions from Bulgaria, Slovakia, Italy and Greece.

Keywords: electromobility,urban transport,electric vehicles,recharging stations
SunOyster cooling (SOcool)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Germany
Call: Stimulating the innovation potential of SMEs for a low carbon and efficient energy system (H2020-SMEINST-1-2016-2017, 2016)
Start date: 2016-08-01
End date: 2017-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Increasing demand for air conditioning with worldwide more than 100 million units of compression air conditioners sold alone in 2014 has led to dramatic growth in electricity demand in many countries, to increasing electricity costs and brownouts. An obvious possibility to counter this trend is to us the same energy for cooling that contributes to the cooling demand – solar energy. The objective of the SOcool Project is to use a concentrating photovoltaic/thermal (CPVT) system combined with chillers to provide the most cost-efficient solar energy on the market in form of electricity, heat and cold. This shall help achieving the 2K target while enhancing the living standard in rather hot climates. The SunOyster is a concentrating solar technology which can generate at the same time electricity and heat with a very high efficiency. From serial production, this will result in very low electricity and heat costs. While the electricity can easily be converted into other forms of energy and can be fed into the grid, the heat is more difficult to convert and has to be used locally. A technically, micro-economically and macro-economically very good form of using the heat in hot climates is converting it into cold for the cooling of buildings. The biggest markets will be Southern Europe (Spain, Southern France, Italy, Greece, Turkey), Northern and Southern Africa, the Gulf region, India, South-East Asia, parts of China, Southern USA, parts of Middle and South America. After entering the market in 2017 with big quantities, we expect growth rates of factor 3 respectively 2 and 1.5 in the following years until 2020 then settle down on growth rates of 10% to 20% in the next decade.

Keywords: concentrating photovoltaic,thermal cpvt,low carbon
Fostering the practical implementation of Open Science in Horizon 2020 and beyond (FOSTER Plus)

Framework: Horizon 2020 — Science with and for Society
Programme: Develop the accessibility and the use of the results of publicly-funded research
Action type: Coordination and support actions
Countries involved: Germany,Germany,Spain,Spain,Netherlands,Netherlands,Denmark,United Kingdom,United Kingdom,United Kingdom,Portugal
Call: Training on Open Science in the European Research Area (H2020-SwafS-2016-1, 2016)
Start date: 2017-05-01
End date: 2019-04-30
Duration (months): 24.0
Total project cost (EUR): 925846.25
EU funding (EUR): 925846.25
Participants: 11
Project status: CLOSED

The FOSTER+ project will focus on promoting the practical implementation of Open Science, with activities targeting academic staff, young scientists and policy-makers in particular. Building on the existing FOSTER portal and training materials, FOSTER+ will develop more advanced-level and discipline-specific materials that build capacity for the practical adoption of Open Science and promote a change in culture. Disciplinary partners in the life sciences, social sciences and humanities will tailor training content to the practices of each domain. Over 50 training events will be delivered, reaching over 4,500 participants. Workshops will be outcome-oriented, providing participants with tangible skills, such as selecting relevant repositories, understanding how to license research data, and negotiating EU data protection laws. FOSTER+ will develop a multi-module Open Science Toolkit, covering key topics such as responsible research and innovation, research data management, software carpentry, text and data mining, reproducible research and open peer review. E-learning courses will be delivered for each module via the Learning Management System and materials will be made available to support face-to-face training delivery. The Open Science Trainer Bootcamp will convene a cohort of trainers with high multiplier potential and equip them to deliver courses within their institution/disciplines. The Bootcamp will be open to both researchers and intermediaries who provide the research environment and infrastructure to support open science. Gamification tools will incentivise the trainer network to add new content to the portal and run more innovative events. Enhancements to content maps and learning structures will enable individualised learning pathways to be recommended to users, and digital badges will be assigned to reward completion. All of the training content will be openly licensed and e-learning materials will be provided in open standards for reuse elsewhere.

Keywords: open science,training,training trainers,open research data,research data management,distance learning
Biomechanics of menisci: a multiscale experimental, theoretical and modelling approach for biomimetic meniscal replacements (MetaBioMec)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Luxembourg
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-11
End date: 2020-06-10
Duration (months): 24.0
Total project cost (EUR): 176123.23
EU funding (EUR): 176123.23
Participants: 2
Project status: CLOSED

The meniscus plays a critical role in load transmission, stability and energy dissipation in the knee joint. Loss of the meniscus leads to joint degeneration and osteoarthritis. In a number of cases replacement of the resected meniscal tissue by a synthetic implant might avoid the articular cartilage degeneration. None of the available implants presents optimal biomechanics characteristic due to the fact the biomechanics functionality of the meniscus is not yet fully understood. Mimicking the native biomechanical characteristics of the menisci seems to be the key factor in meniscus replacement functioning. This is extremely challenging due to its complex inhomogeneous microstructure, the lack of a full experimental characterization of the material properties and the lack of 3D theoretical, numerical and computational models which can reproduce and validate the experimental results. Therefore, the aim of this work is a thorough understanding of the menisci biomechanics with the view of translating the knowlege to the orthopeadic implants arena. The objective of the proposal be achieved through (i) designing and performing a range of innovative experimental tests to characterize the behaviour of the meniscus tissue at the micro and macroscale, (ii) building an appropriate and novel multiscale anisotropic model at the tissue level which takes into account the fractal dimension of the porous menisci’s tissue, (iii) implementing the material model in commercial finite element (FE) software and (vi) build and validate an accurate FE biomechanical model of the knee joint (which includes the meniscus) in order to model the biomechanical behaviour of the menisci when subjected to a range of mechanical stress which is not reproducible in an experimental context.

Keywords: menisci biomechanics,multiscale poro mechanics,fractional models,anisotropy
Mechanism of nucleosome assembly during DNA replication (EpiRep)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: Biological Mechanisms, Structures and Functions
Panel description: Molecular biology, biochemistry, structural biology, molecular biophysics, synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: Netherlands
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2019-12-01
End date: 2024-11-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Proper inheritance of the epigenetic information during cell division controls cell fate decisions, tissues homeostasis and development, ensuring disease avoidance. We have little understanding however of the mechanisms by which epigenetic information, specifically histone post-translational modifications in nucleosomes, are replicated in parallel to the DNA prior to cell division. This process strictly depends on proper nucleosome formation on the newly synthesized DNA strands. Here, I will study the molecular mechanism of nucleosome assembly during DNA replication. Nucleosome dynamics during DNA replication is controlled by an interconnected network of histone chaperones that converges on the key Chromatin Assembly Factor 1 (CAF-1). I recently elucidated the molecular mechanism of CAF-1-mediated nucleosome assembly, in absence of any other replication components. I developed a quantitative (NAQ) assay that allows, for the first time, the quantification of nucleosome assembly activity in vitro. In cells, CAF-1 is recruited to replication forks by the DNA polymerase processivity factor PCNA. Here, I will capitalize and expand on the assays above to integrate structural data, quantitative biochemical and biophysical measurements, and functional analyses, to elucidate how CAF-1 crosstalks to PCNA, DNA polymerases and other components of the DNA replication machinery in S phase. Specifically, the proposed research will 1) uncover how CAF-1 recruitment by PCNA affects its function in nucleosome assembly, and 2) examine how CAF-1 activity is regulated during ongoing DNA replication. This work will reveal the mechanism of nucleosome assembly during DNA replication and its interplay with S phase signaling. A mechanistic understanding of this pathway will uncover the fundamental principles that control genome and epigenome stability, thus cell fate decisions and disease avoidance.

Keywords: chromatin,in vitro reconstitutions,histone chaperone
Science for Climate (SCICLI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Portugal,Portugal,Portugal,Portugal
Call: European Researchers' Night (H2020-MSCA-NIGHT-2020bis, 2020)
Start date: 2021-05-01
End date: 2021-12-31
Duration (months): 8.0
Total project cost (EUR): 147363.0
EU funding (EUR): 147363.0
Participants: 9
Project status: CLOSED

The European Green Deal proposes the EU to be climate neutral by 2050 by promoting a series of initiatives that will protect the environment and boost the green economy, cutting pollution. This proposal uses the motto "Science for Climate" (SCICLI) as a point of departure to achieve two main goals: (i) raise Portuguese citizens' awareness, particularly young people, towards innovation and research being conducted in Europe to develop green technology, industry and transport and to preserve ecosystems and natural resources; and (ii) bring researchers closer to civil society, enabling meaningful opportunities for communities to express their concerns and expectations about research and, more generally, about science to face climate changes. This direct connection with people's concerns allows a simple contact among all social players, responding to Responsible, Research & Innovation (RRI) goals, and brings the public attention to the need of promoting social cohesion and inclusion while preserving cultural identity and responding to the European Green Deal. The SCICLI proposal for the European Researchers' Night (ERN) 2021 will therefore rely on the social, economic and environmental dimensions for sustainability, while promoting the relevance of science and research to contribute for climate neutrality in the future. SCICLI will involve large segments of the scientific community in public engagement and science communication/awareness activities during the ERN and build-up activities. It will go where citizens are: this project proposes to reach four regions/cities from North to South of Portugal, involving six universities, municipalities and new research institutions from different scientific areas. It will target all age groups, with special focus on young people who are being pressured to adapt to the consequences of global changes in the next decades, and encouraging them to actively contribute with solutions by choosing scientific careers.

Keywords: climate neutrality,sustainability,green economy and technology,ecosystems preservation,youngsters in science
GÉANT Research and Education Networking - Framework Partnership Agreement Proposal (GEANT2020)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: e-Infrastructures
Action type: Framework Partnership Agreement
Countries involved: Germany,Estonia,Italy,Austria,Spain,Israel,Albania,Armenia,Ukraine,Azerbaijan,Ireland,Malta,Cyprus,Bulgaria,Slovakia,Serbia,Lithuania,Greece,North Macedonia,Belgium,Hungary,Slovenia,Belarus,Türkiye,Croatia,Poland,Romania,Switzerland,Moldova, Republic of,Georgia,Latvia,France,Czechia,Netherlands,Netherlands,United Kingdom,Montenegro,Portugal,Luxembourg,Denmark,United Kingdom
Call: Research and Education Networking – GÉANT (H2020-EINFRA-2014-2, 2014)
Start date: 2015-04-23
End date: 2020-12-22
Duration (months): 68.0
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 43
Project status: SIGNED

In this Framework Partnership Agreement (FPA) the European National Research and Education Networks, united in the GÉANT partnership, propose to implement the European Communications Commons, as stipulated in the GÉANT Expert Group report of October 2011. The proposal defines the scope and priorities to be observed in the Specific Grant Agreements (SGAs) that will define the work in detail. The FPA aims to "...make every European researcher digital, increasing creativity and efficiency of research and bridging the divide between developed and less-developed regions.” The future GÉANT infrastructure will provide secure, cost-effective, highly available and reliable services for very high-speed connectivity, identity inter-federation, resource virtualisation, mobility, security and trust, ensuring the digital continuum of services to the Research and Educational users anywhere in the EU whether at home or on the move. Further development of the Authentication and Authorisation Infrastructure, in terms of footprint and providing seamless and unimpeded access to relevant data and computing resources from anywhere, is a strategic component in this endeavour and will be undertaken in cooperation with the other European e-infrastructure providers and projects. By the very nature of the FPA, the current proposal does not include any specific work, budgets, deliverables or milestones. These details belong to the future SGAs. The vision presented here is a general overview of the actions to be proposed under the framework. The FPA will be governed by a General Assembly with advisory bodies and committees ensuring that users’ views, as well as senior industry and service provider expertise, contribute to the strategic governance. One of the most successful attributes governed by the Cost Sharing Committee of the GEANT cooperation over the past decade is the ability to agree and to share costs across a greatly diversified Europe.

Keywords: unified,knowledge creation,communication commons,connecting,empowering,innovation,learning,governance,research networking,multi domain networking,secure,trust,e infrastructure