Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Development of Functional Conjugated Two-Dimensional Metal-Organic Frameworks (FC2DMOF)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure-properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-02-01
End date: 2025-07-31
Duration (months): 66.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Metal-organic frameworks (MOFs) have been highlighted for catalysis, gas storage and separation. However, due to low conductivity (<1E-8 S/cm), weak magnetic interaction as well as difficult device integration, the application of bulk 3D MOFs in (spin-)electronics is challenging. Recent advances disclose that the designs of conjugated 2D MOFs (C2DMOFs) have led to improved intrinsic conductivity (up to 1000 S/cm). However, the related research remains immature due to lack of high-quality film samples, very limited structural types and elusive transport mechanism. In this project, we will develop unprecedented magnetic (semi-)conductive C2DMOFs and accomplish electronic/magnetic structure engineering for functions in electronics and spintronics. Here, we will synthesize novel conjugated monomers to tune geometries and pore sizes of C2DMOFs, thus achieving in-plane engineering on charge and spin distribution. We will develop versatile synthesis strategies towards highly crystalline C2DMOF films/nanosheets: (1) develop solvothermal synthesis and subsequent electrochemical exfoliation of layer-stacked bulk samples into 2D nanosheets; (2) develop air/liquid and liquid/liquid interfacial synthesis of large-area single-/few-layer films; (3) particularly establish a ground-breaking chemical vapor deposition (CVD) synthesis route for “clean” single-crystalline films. We will further establish unprecedented C2DMOF-based 2D-2D van der Waals heterostructures (vdWHs) with other inorganic 2D crystals to realize out-of-plane engineering on band gaps and unique interfacial transport characteristics. By employing the developed C2DMOFs and vdWHs, we will explore magnetism and temperature-/magnetic field-depended charge transport properties. As the key achievements, we expect to establish novel electronic/magnetic structures and general synthesis strategies, delineation of reliable structure-transport relationships and superior device performance of C2DMOFs.

Keywords: 2d materials,metal organic frameworks,2d polymers,organic electronics,magnetics
MASTERCOW, an antibiotic-free bioinorganic therapy for bovine mastitis (MASTERCOW)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Italy
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2018-08-01
End date: 2019-01-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Bovine Mastitis is a bacterial infection of the cow udder. It is the major problem in the dairy sector, causing losses of approximately €1.5Bn in Europe each year, with each case costing the farmer over €400/case. Current mastitis treatment is very inefficient and is wasteful. Indeed, most part of current treatments use conventional antibiotics. These solutions are not ideal: - they are not always effective - bacteria can gain resistance to the antibiotics - for a period of time during and following treatment (the 'withdrawal period' which can be up to 9.5 days) the milk must be discarded to prevent entry of antibiotic residues into the human food chain. CNTLAB, the SME proposers, has developed a totally new approach in bovine mastitis therapy: MASTERCOW. Unlike antibiotics which can be ineffective and carry the risk of resistance, MASTERCOW allow to achieve a strongly increased cure rate (from 70% up to 99%), with a lower cost, decreased therapy duration ensuring wellbeing of the cow. MASTERCOW is an intramammary technological mixture, based on Bioinorganic chemistry, that is directly nebulised through the orifice of the mammary gland of the milk cow. MASTERCOW has been already tested in ab environment and we received expression of interest from breeders willing to launch a demo project. The market we are targeting has an overall value of 1,5B€ (therapies for dairy cow mastitis) and we aim at reaching 9% of this sector, foreseeing 14M€ turnover at Y4. MASTERCOW has the potential to create a totally new market in mastitis therapy: antibiotic-free therapies. The PH1 project will aim at validating the product concept on the market and at fine tuning the distribution strategy by identifying the right commercial partners in addressed markets. We will also run a small pilot test, to validate MASTERCOW approach. The product is brought to the market by CNT LAB, an Italian startup that patented the ion cluster synthesis MASTERCOW product is based upon.

Keywords: dairy,bovine mastitis,animal wellbeing
Dynamical constraints for the predictability of heat waves in current and future climates (HEATforecast)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Earth system science
Panel description: Physical geography, geology, geophysics, atmospheric sciences, oceanography, climatology, cryology, ecology, global environmental change, biogeochemical cycles, natural resources management
Countries involved: Switzerland,Switzerland
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-03-01
End date: 2025-08-31
Duration (months): 66.0
Total project cost (EUR): 1499849.0
EU funding (EUR): 756125.0
Participants: 2
Project status: SIGNED

In summer 2018, a devastating heat wave affected the entire Northern Hemisphere. Climate change projections indicate that the severity and frequency of such heat waves will further increase over the next decades. At the same time, models remain unable to predict heat waves at lead times of a few weeks – a crucial planning timescale. The poor prediction skill at timescales of weeks to months is to a large extent due to an incomplete understanding of the underlying physical drivers of heat waves. In particular, the atmospheric fluid dynamics responsible for heat waves and their prediction are not sufficiently understood and tend to be biased in models. The seasonal cycle further modulates the drivers and predictability of heat waves. Climate change projections disagree on the changes in atmospheric dynamics responsible for heat waves. The proposed research takes an unconventional path to address these open questions by building a process-based hierarchy of prediction systems ranging from a dry dynamical core to a prediction system using full physics. This hierarchy approach is novel for prediction systems. By systematically adding processes to the model, the relative contribution of atmospheric dynamics and surface drivers for heat waves and their predictability can be estimated throughout the seasonal cycle and for the projected changes in heat waves with climate change. While solving a fundamental question in atmospheric fluid dynamics, the proposed research aims to significantly extend the warning horizon and thereby minimize the societal consequences for future heat waves, which are expected to increase in frequency but so far remain unpredictable. This project combines the experience and strengths of the PI in atmospheric dynamics, predictability, and their application in a timely manner by increasing the connections between the dynamics and predictability communities that will benefit the study of atmospheric fluid dynamics and predictability beyond heat waves.

Keywords: heat wave,atmospheric dynamics,jet stream,simplified model,model hierarchy,teleconnection
Encompassing Training in fUnctional Disorders across Europe (ETUDE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany,Germany,Germany,Italy,Poland,Netherlands,Netherlands,Netherlands,United Kingdom,United Kingdom,Denmark
Call: Innovative Training Networks (H2020-MSCA-ITN-2020, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 4067173.08
EU funding (EUR): 4067173.08
Participants: 13
Project status: SIGNED

Functional Disorders (FD) are clusters of chronic somatic symptoms that currently cannot be associated to reproducibly observable pathophysiological mechanisms. FD can affect every organ system, individuals of all ages, ethnic groups and socioeconomic strata, although the risk is increased in women and lower socioeconomic strata. Women are 9 times more likely to receive an FD diagnosis, even after adjustment for the severity of symptoms. Functional limitations are as severe in FD as in well-defined chronic physical diseases. Direct medical costs and indirect costs as a consequence of sick leave and disability are high. FD cause relevant annual excess costs in health care that are comparable to mental health problems like depression or anxiety disorders, and which may be reduced by interventions targeting physicians as well as patients. About 7% of the population is affected to such a degree that they qualify for psychiatric treatment. However, this remains hidden due to diagnostic practices that vary between fields. Psychosomatic medicine, clinical psychology and medical specialties all have their own and different concepts of FD having important consequences for patients. These challenges result in a lack of knowledge on FD, leading to fragmented and insufficient health care for patients with FD, and a society in which patients with FD experience stigma from both the society as well as from health care professionals. There is an urgent need to solve the fragmented and insufficient education and research landscape. Therefore, the goal of ETUDE is the development of a sustainable and structured training programme in order to educate a new generation of interdisciplinary creative early stage researchers that are able to cross disciplines and to translate theory and experimental models to products and services that improve care for patients.

Keywords: functional disorders,mechanisms,diagnosis,treatment,stigma
Accessing hot-spots in plasmonic nanoantennas (HOTSPOT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-05-01
End date: 2017-04-30
Duration (months): 24.0
Total project cost (EUR): 183454.8
EU funding (EUR): 183454.8
Participants: 1
Project status: CLOSED

Guiding molecules/nanomaterials to the right place in plasmonic nanoantennas is a key problem to be solved in order to benefit from the high electromagnetic field localization offered by these materials. Accessing these nanoscale-regions remains a significant challenge in plasmonics and is the main goal of this project. The novel approach introduced here is based on the field-enhancement properties of the nanoantennas, thus spatially selective to the hot-spots. This easy, fast and cheap strategy can allow selective and large-scale positioning of any kind of molecules and/or nanomaterials in a variety of plasmonic-nanoantenna hot-spots, independently of their shape and resonance position. This strategy can solve the big challenge of hot-spot modification in plasmonic nanoantennas thus opening new doors to many real applications ranging from biosensing to energy conversion.

Keywords: plasmonic nanoantennas,hot spots,self assembled monolayers,hot electrons
Social and Political Economics: Theory and Evidence (ECOSOCPOL)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance and management
Countries involved: Sweden
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-11-01
End date: 2022-10-31
Duration (months): 72.0
Total project cost (EUR): 1104812.0
EU funding (EUR): 1104812.0
Participants: 1
Project status: SIGNED

In this project, I will study how individual and social motives interact to drive individual decisions, a question that has fallen between the cracks of different social-science approaches. I will use a common theoretical framework to approach an important, but badly understood, general question: do social motives reinforce or weaken the effect of changes in individual motives? By modifying this common framework to different applications, I will consider its predictions empirically in different large data sets with individual-level information. The planned applications include four subprojects in the social, political, and economic spheres: (i) decisions in China on the ethnicity of children in interethnic marriages and matching into such marriages, (ii) decisions on tax evasion in the U.K. and Sweden, (iii) decisions to give political campaign contributions in the U.S., and (iv) decisions about fertility in Sweden. I may also spell out the common lessons from the results on the interaction between individual and social motives in monograph format intended for a broader audience.
Exploring topological matter with atomic Dysprosium (TOPODY)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: France
Call: ERC Starting Grant (ERC-2017-STG, 2017)
Start date: 2018-01-01
End date: 2024-06-30
Duration (months): 78.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

Recently, topology stepped in an increasing number of areas in physics, including via the concept of topological phases of matter. In strongly interacting systems, topological phases may exhibit intricate quantum entanglement between their constituents, leading to fascinating physical properties, such as the emergence of anyons. Since the discovery of fractional quantum Hall states in 1982, the scientific community is awaiting further experimental advances: new types of strongly correlated states, observation/manipulation of anyons. In this field, ultracold atoms promise novel approaches with a specific degree of control. Yet, despite the recent creation of weakly interacting topological states with atomic gases, reaching the strongly correlated regime, with long-range quantum entanglement, remains an open challenge. In TOPODY, I will use a novel approach to produce strongly correlated topological states with microscopic samples of atomic Dysprosium. The envisioned laboratory experiment will combine state-of-the-art techniques, such as single-atom detection or laser-induced spin-orbit coupling. It will allow preparing quantum gases subjected to artificial gauge fields beyond the previously accessible regimes. The project will focus on realizing two paradigmatic physical systems – the Laughlin state and a topological superfluid. 1. We will create the Laughlin state by injecting a controlled amount of angular momentum using optical transitions with finely-shaped laser beams. We will infer distinctive features of the Laughlin state – incompressibility and atom anti-bunching – from the distribution of atom positions. 2. We will produce strongly interacting Fermi gases in one dimension and subjected to a spin-orbit coupling, leading to a topological superfluid state. The topology will manifest itself by the presence of Majorana bound states, which are quantum states delocalized between the two ends of the system, and accessible using quasi-particle spectroscopy.

Keywords: quantum gases,quantum hall effect,topological matter
Unveiling expectancy neuronal coding in the cerebral cortex induced by naturalistic tactile stimuli (Expectancy)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-03-01
End date: 2019-02-28
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 1
Project status: CLOSED

Expectancy is a major function of the nervous system that prepares the organism to react in a meaningful way to sensory stimulation. Depending on local statistics of patterned sensory stimuli, the nervous system shows preparedness for expected inputs. This allows to respond or not in a short time window by taking into account recent presentations of a similar sensory context. In order to gain insight into the underlying neural coding, I propose to use the vibrissal system of the rat applying controlled sensory inputs. The vibrissal system contains an array of specialized vibrissae as the input stage of an extremely sensitive tactile system. Significant innovation will be the use of a stimulation matrix allowing independent deflection of 24 vibrissae. This novel tool will help to generate short-term expectancies by introducing complex and precisely timed specific sensory inputs. I propose to combine in vivo intracellular and multi-unit extracellular recordings in the primary somatosensory cortex (SI) with multi-whisker stimulation. I hypothesize that neural information coding is shaped by the statistics of the time-varying vibrissa contacts. The ability to generate expectancy signals will be compared for repetitive contacts as with natural objects and un-natural sequences to which the system is not preadapted. In addition to the common lightly anesthetized rat preparation, I propose to develop a novel design to record from awake animals. Furthermore, I will assess expectancy using dynamical systems techniques by modeling this process as forced coupled nonlinear oscillators. The proposed project will elucidate how natural tactile patterns are encoded in SI through a comprehensive approach including electrophysiology, sophisticated tactile stimulation and dynamical modeling. It will be the first to clarify the coding principles of predictable sensory inputs generating neuronal expectancies and can provide insight into the general mechanisms of prospective judgment.

Keywords: expectancy,whisker system,somatosensory system,neural coding
Security controversies: exploring the governance of knowledge, innovation and techno-scientific risks (SECCON)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Austria
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-05-01
End date: 2020-04-30
Duration (months): 24.0
Total project cost (EUR): 178156.8
EU funding (EUR): 178156.8
Participants: 1
Project status: CLOSED

The EU is one of the key proponents of knowledge-based economy, i.e. an economic system based on research, development, and knowledge production. However, techno-scientific progress may bring not only benefits and well-being to the society, but also undesired side-effects and new dilemmas. Apart from social, ethical, or environmental controversies that scientific research opens, innovation is now increasingly linked with security controversies, characterized by the concerns over a potential misuse of science for hostile purposes. Yet with the ever-accelerating speed of scientific inquiry and the rise of interdisciplinary and international connections, it becomes impossible to clearly define and police “dangerous” research that could be exploited by terrorists and criminals. To balance the demands for scientific openness with national security interests, new techniques of governance are introduced in science, which integrate the existing principles of scientific responsibility with security practices restricting the mobility of scientific knowledge. This project aims to build a unique body of interdisciplinary expertise to study security controversies in the governance of research and innovation. It will link researchers from security studies and science and technology studies with leading biotechnological stakeholders in Austria and practitioners of Responsible Research and Innovation (RRI) involved in ethics review of EU research projects. Specifically, the project will, first, situate the current security controversies historically and theoretically, second, map the techniques of knowledge governance in health-data governance and RRI, and third, explore what competences and skills are required in the assessment of security risks of scientific knowledge mobility in the two empirical areas. In sum, the project will set out a research agenda to study how our societies design, implement, and regulate sensitive and potentially dual-use research and innovation.

Keywords: emerging technologies,dual use,misuse of science,knowledge politics,responsible research and innovation rri,security,risk,securitization