Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Functional Coordination Chemistry (FCC)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: ERC Advanced Grant Interdisciplinary Panel
Countries involved: United Kingdom
Call:  (ERC-2010-AdG_20100224, 2010)
Start date: 2011-06-01
End date: 2016-05-31
Duration (months): 60.0
Total project cost (EUR): 2498552.0
EU funding (EUR): 2498552.0
Participants: 1
Project status: CLOSED

To address critical problems in the natural sciences by developing the chemistry of metal coordination complexes, harnessing the unique ground and excited state properties of the lanthanide (III) ions to impart the required function into the complexes and their conjugates. This requires PI-led collaborative work in molecular design and instrumentation development. Objectives 1. To measure changes in the concentration of essential bioactive species in particular compartments of plant and animal cells, including chiral species. This requires the creation of targeted luminescent probes that relay an optical signal to the observer, signalling changes in the concentration of these species, with high spatial and temporal control. In parallel, circularly polarised emission microscopy will be pioneered. 2. To enable 19F magnetic resonance studies to be undertaken much more widely by devising functional paramagnetic 19F-magnetic resonance probes, with fast relaxation and enhanced chemical shift dispersion.

Keywords: chirality
Organisation of EuroNanoForum 2011 (ENF 2011)

Framework: FP7 — Cooperation
Programme: Nanosciences, Nanotechnologies, Materials and new Production Technologies - NMP
Destination: Integration
Action type: Coordination and support actions
Countries involved: Hungary,Finland
Call:  (FP7-NMP-2010-CSA-4, 2010)
Start date: 2010-10-01
End date: 2011-07-31
Duration (months): 10.0
Total project cost (EUR): 568758.88
EU funding (EUR): 400000.0
Participants: 2
Project status: CLOSED

The EuroNanoForum 2011 (ENF 2011) will be organised by the National Office for Research and Technology in Hungary, and will be a prominently featured in the Hungarian EU Presidency programme of 2011. The event wil be organized from 30 May – 1 June, 2011, starting with 2-day conference featuring distinguished speakers to initiate stimulating discussions and exchange ideas on key policy, scientific, industrial and societal issues in nanotechnology. A third day will be dedicated to networking between stakeholders involved in European Technology Platforms to discuss strategic research priorities, and between researchers and industrial actors to initiate future cooperation in research and innovation. The conference will be enriched with a lively accompanying industrial and research exhibition. Furthermore, the EuroNanoForum 2011 will be organized at a critical time in the debate to formulate future strategic priorities in nanotechnology up to 2020 for the next Strategic Nanotechnology Action Plan, and offer input for defining research priorities of the NMP theme of the 8th Framework Programme. ENF 2011 will be held on the eve of the first anniversary of the integrating technology platform, the NANOfutures initiative, and thus ideally aligned to discuss its first propositions for cross-sectoral cooperation needs.

Keywords: nanosciences,nanotechnology,conference,euronanoforum
Fabrication of particles with photo receptors: bio-analytical application such as controlled drug delivery (PHOTORELEASE)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,United Kingdom,France,Spain,Spain
Call:  (FP7-PEOPLE-2010-IRSES, 2010)
Start date: 2011-09-01
End date: 2014-08-31
Duration (months): 36.0
Total project cost (EUR): 186200.0
EU funding (EUR): 186200.0
Participants: 5
Project status: CLOSED

The importance of carbon-based materials in biological applications has been recognized. Especially, nanodiamond particles (referred to as nanodiamonds, NDs) have started to emerge as novel candidate for promising applications in the field of nano-biotechnology as imaging probes and drug carriers. NDs do not show the toxicity of other nanoparticles, notably gold, making them ideal nanoscale drug delivery platforms. Furthermore, NDs can exhibit intrinsic fluorescence from point defects making them candidates for biomedical imaging applications. ND particles are particularly attractive for biomedical applications as functionalization and biomolecule immobilization are readily accomplished. Triggered drug release allows the functionalized NDs to find their targets before the drugs are activated by local conditions. In this sense, the NDs are performing the well established role of postdrugs, smuggeling the inactive compound to their targets where they are released through bond cleavage. The objective of the proposed program concerns the fabrication of NDs modified with photo-label linkers where different molecules can be directly attached, without chemically modification of the biomolecule itself. In a proof of principle, horse radish peroxidase (HRP) will be linked to NDs modified with the photo-label o-nitrobenzyl group and the release followed by UV/Vis. In a later state the controlled release of drugs such as ibuprofen, adriamycin or antigens will be looked at. The proposed research project brings together centers from France, the UK, Spain and the Ukrain. The network offers training in the fabrication and characterization of new materials for biological applications.

Keywords: magnetic particles,diamond nanoparticles,drug release,phot linker
Exploiting plants for the production of future generation recombinant pharmaceuticals (FUTURE-PHARMA)

Framework: FP7 — Ideas
Programme: European Research Council
Theme: European research council
Destination: Advanced grants
Action type: Support for frontier research (ERC)
Panel: Applied life sciences and biotechnology
Countries involved: United Kingdom,Germany
Call:  (ERC-2010-AdG_20100317, 2010)
Start date: 2011-08-01
End date: 2019-01-31
Duration (months): 90.0
Total project cost (EUR): 3488863.0
EU funding (EUR): 3488863.0
Participants: 2
Project status: CLOSED

Biopharmaceutical proteins are typically produced in cultivated mammalian cells, a costly process with limited scalability. Thus products such as monoclonal antibodies are very expensive and often beyond the reach of the world’s poor. The problem is compounded by the fact that important strategies for preventing diseases such as HIV and rabies typically involve large doses of multiple antibodies and other virucidal proteins. Plants have emerged as alternative production platforms for biopharmaceutical proteins because they are less expensive, more scalable and potentially could be transferred to developing countries. Recently, the first products have reached the clinic, but many of them are follow-on products already manufactured in mammalian cells. Here, Prof Julian Ma (St George’s Hospital Medical School, London, UK) and Prof Dr Rainer Fischer (RWTH Aachen University, Germany) aim to develop innovative ways to use plants for the economical, safe and sustainable production of combinations of active pharmaceutical ingredients (APIs) based on recombinant proteins, thereby pushing the boundaries of what can be achieved in plants beyond current capabilities with fermenter-based systems. We will focus on the production of antibodies and lectins against HIV and rabies, with the aim of generating GMP-compliant microbicidal cocktails for evaluation in human trials. Key aspects of the project will include the production of APIs both individually and as combinations in plants, the development of technologies allowing the introduction of transgenes into pre-determined genomic loci, the use of click chemistry to optimize the production and stoichiometry of recombinant protein cocktails, the development of candidate products for both topical and parenteral administration and the development of downstream processing concepts that are transferrable to developing countries, such as minimal processing and processing trains based on pre-assembled disposable modules. We will complete one Phase I clinical trials, each testing a plant-derived product that advances the field in a significant way

Keywords: recombinant,monoclonal antibody,microbicide,hiv,rabies,protein cocktail,cgmp,tobacco,plant biotechnology,transgenic,clinical trial,pharmaceutical,developing country
Micro- Multi-Material Manufacture to Enable Multifunctional Miniaturised Devices (M6)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany
Call:  (FP7-PEOPLE-2010-IRSES, 2010)
Start date: 2011-07-01
End date: 2015-06-30
Duration (months): 48.0
Total project cost (EUR): 655200.0
EU funding (EUR): 529200.0
Participants: 2
Project status: CLOSED

For some decades the world has been able to see the ultimate impact of device miniaturisation which has led to dramatic growth in national and global revenues alongside the huge benefits that have been brought to human activities, in the healthcare/medical, energy, space, transport, communication and defence sectors. Evolving initially from silicon based manufacturing technologies thanks to the huge investment and established infrastructure, current state-of-the-art play in moving further according to the “More than Moore” has substantially extended the global capacity in achieving complex microsystem integration using hybrid processes, multi-materials that are significantly confined in an ever small space or dimensions. The challenges in the endeavour of continuous miniaturisation therefore exist in the fundamental understanding of the phonemes behind all the play, in order to underpin a paradigm of future generation miniaturised device. With significant developments for some decades the various capabilities and expertise bridging the EU and Asia are now available to readily forge a tangible strong consortium targeting such an important field. Given its inter-disciplinary nature, the project will cover a wide breadth of research topics as demanded through collaborations and researchers’ mobility provided by International Research Staff Exchange Scheme as one of the Marie Curie Actions to draw the strength from the representative institutions in Germany, Japan, China and UK. The project will focus on the potential challenges and potential issues encountered in the integration of miniaturised devices in terms of novel materials and processes, characterisation and testing, demonstrating the manufacturability and reliability. Both experimental and computational approaches will be applied to elaborate the fundamental aspects of multi-material behaviour at micro- and nano-scales.

Keywords: microsystems,materials engineering,microengineering,interactive surfaces,health monitoring,miniaturised devices,novel materials and manufacturing processes
Building a Visual Brain for Fast Human Machine Interaction (EYE2E)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom,Germany
Call:  (FP7-PEOPLE-2010-IRSES, 2010)
Start date: 2011-08-01
End date: 2015-07-31
Duration (months): 48.0
Total project cost (EUR): 798000.0
EU funding (EUR): 798000.0
Participants: 2
Project status: CLOSED

Effective computer vision is a major research challenge. Vision plays a critical role in the interaction of most animal species with a dynamic world, and even relatively low order animals have remarkable visual processing capabilities. However, much research in neural vision has been based upon general computing systems, whereas the powerful parallel computing capacity of visual neural systems can only be fully demonstrated and utilized when realized in Very Large Scale Integrated (VLSI) chips. Focusing on modelling biological visual neural systems and realizing them in chips for human-machine interaction, the research staff exchange programme will bring opportunities for the four partners to work together and complement each others’ research strengths via research staff secondments, training seminars, joint workshops and jointly organised conferences, to explore the multidisciplinary research area and to build strong connections between the European institutions and partner institutions in a fast growing economy. Five work packages (WPs) are designed to achieve the objectives of the project: WP1: biological plausible visual neural system modelling, WP2: multiple visual neural systems integration, WP3: VLSI neural vision chip design, WP4: biologically plausible vision systems for human-machine interaction, and WP5: management, networking and dissemination.

Keywords: vision,biological visual neural systems,model,multiple neural sytems integration,vlsi,vision chip,robotics,human machine interaction
Belgian EU Presidency Conference on Infrastructures for Energy Research (ENERI 2010)

Framework: FP7 — Capacities
Programme: Research Infrastructures
Destination: Resilient Infrastructure
Action type: Coordination and support actions
Countries involved: Belgium
Call:  (FP7-Adhoc-2007-13, 2007)
Start date: 2010-05-01
End date: 2011-02-28
Duration (months): 10.0
Total project cost (EUR): 194280.0
EU funding (EUR): 130000.0
Participants: 1
Project status: CLOSED

The project aims to organize a conference on Infrastructures for Energy Research (ENERI 2010) during the Belgian Presidency of the European Council. The conference will be a 1.5 day event held in Brussels in the new conference facilities Square Brussels Meeting Centre on the 29th and 30th of November 2010. The target group is the scientific community, R&D and science policy managers, the energy sector and industry, policy decision makers (250-300 participants, on invitation only). The conference aims to contribute: - to the development of a comprehensive strategy for research infrastructures in the energy field at pan-European level, in the framework of the European SET-Plan and of the ESFRI Roadmap, - to the analysis of the impact of RIs (including e-infrastructures) on the implementation of energy policies and sustainable development and - to the identification of possible actions to increase the human capital affecting the implementation of the energy research projects.

Keywords: research infrastructures,energy,set-plan,esfri roadmap,support activity
Fullerene-based systems for oxidative inactivation of airborne microbial pathogens (NANO_GUARD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Portugal,Sweden,Israel
Call:  (FP7-PEOPLE-2010-IRSES, 2010)
Start date: 2011-10-01
End date: 2015-09-30
Duration (months): 48.0
Total project cost (EUR): 844200.0
EU funding (EUR): 844200.0
Participants: 4
Project status: CLOSED

The main goal of this project is to establish a long-lasting collaboration and create a network of the research centres of excellence from Europe and Third Countries aiming at development of the Fullerene-based systems for oxidative inactivation of airborne microbial pathogens. This goal will be achieved by undertaken of joint research activities via collaboration of a multidisciplinary consortium in molecular microbiology, virology, health care, environmental physics, green chemistry and material science, facilitated by individual mobility of the researchers between Europe and Third Countries. The main research objectives of the proposal are: • To elaborate novel fullerene-based composites in form of thin and thick films, membranes and individual fullerene molecules imbedded in 3-D porous matrixes. • To evaluate the ability of the fullerene-based materials of different morphology to produce singled oxygen under Solar irradiation. • To evaluate the performance of the elaborated C60– based oxidative systems to inactivate the microbial pathogens — bacteria, viruses, fungi, mold spores. • To design and elaborate the lab-scale fullerene-based oxidative system Prototypes to be submitted to a tough testing of the performance criteria towards airborne pathogens inactivation in air-conditioning installations. Other objectives of the proposed collaboration are aimed at: • increasing individual mobility and career prospects of each person involved; • facilitating transfer of knowledge between research groups involved via exchange visits; • providing training opportunities for early stage researchers; • disseminating results of the exchange activities; The main expected scientific results: • Novel fullerene–based composites with optimal system design and high antimicrobial/ antiviral performance under Solar irradiation. • Prototype system to be submitted to a tough testing of airborne pathogens inactivation in air-conditioning installations

Keywords: environmental physics,material science,nanomaterials,fullerene-based composites,photosensitization,solar irradiadion,molecular microbiology,bacteriology,virology,biomaterial engineering
Dynamics and Cooperative Phenomena in Complex Physical and Biological Media (DCP-PHYSBIO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France,Germany,Germany,United Kingdom,Israel
Call:  (FP7-PEOPLE-2010-IRSES, 2010)
Start date: 2011-04-25
End date: 2015-04-24
Duration (months): 48.0
Total project cost (EUR): 412300.0
EU funding (EUR): 412300.0
Participants: 6
Project status: CLOSED

The goal of the DCP-PhysBio exchange program is to bring together several European teams (France, Germany, UK), Israel, as well as partners from Russia and Ukraine. We want to use our combined expertise to study various challenging dynamical and cooperative phenomena taking place in complex physical and biological systems. All the teams have a track record of research in these areas concentrating on particular numerical or theoretical facets, such that the network will synergistically amplify their strengths. The staff exchanges will include both a team research work on specific work packages which will further consolidate the research partnership, and a transfer of knowledge component of workshops, schools and seminars which will ensure an effective dissemination of results and foster interactions amongst the young researchers. If the aims of our proposal are to be achieved, then not only that a long-term research network will emerge but a number of PhD students and early career researchers will have had been mentored into, and intensively exposed to, a culture of international collaborative research.

Keywords: statistical physics,complex systems,disordered media,biophysics,computational biology
Nanostructured composite materials (NANOCOM)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Research Staff Exchange Scheme
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Finland,United Kingdom,Switzerland
Call:  (FP7-PEOPLE-2010-IRSES, 2010)
Start date: 2011-04-01
End date: 2015-03-31
Duration (months): 48.0
Total project cost (EUR): 161500.0
EU funding (EUR): 161500.0
Participants: 3
Project status: CLOSED

In the search for new materials with enhanced functionality, glassy nanocomposites comprising of nanoparticles of different nature in glassy matrix are of special interest. In the case of metal nanoparticles this is because the pronounced surface plasmon resonance, which dominates the optical properties of glass-metal nanocomposites (GMN) and provides high optical nonlinearity of GMN due to additional enhancement of the electric filed in the vicinity of the nanoparticles. This resonance can be coupled to other resonances of different nature, like Bragg-type resonance mode in periodic medium or resonant electronic transition in glass doped with ions of rare-earth or tran-sition metals. The strong coupling of surface plasmon to other resonant modes differing in origin can dramatically enrich the optical properties of GMN enabling photonics materials with strong and fast optical nonlinearity and spectral tunability. Modification of metal nanoparticles with, e.g., femtosecond laser irradiation can modify spectral properties and even change the temporal dynamics of the plasmon mode and such manner enrich functionality of the GMN. In the framework of the NANOCOM we will develop innovative approach to development of novel materials based on nanostructuring glassy composites and will create such materials. The research objectives of the NANOCOM are modeling, manufacturing and investigation of (i) sub-micron patterned nanocomposites, (ii) GMN comprising of bimetallic nanoparticles, and (iii) GMN modified with femtosecond laser pulses. We anticipate that theoretical and experimental results of NANOCOM will provide new insights in the mechanisms of the linear and nonlinear response of nanocomposites on electromagnetic fields. New functionalities arising from the coupling of resonant excitations of different ori-gin and to the modification of GMN response by fs laser processing will enable development of advanced glassy materials for photonic and electronic applications.

Keywords: photonic components