Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Entanglement-Assisted Thermoelectric Transport in Quantum Systems (EATTS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-01-13
End date: 2027-01-12
Duration (months): 24.0
Total project cost (EUR): 188590.08
EU funding (EUR): 188590.08
Participants: 1
Project status: SIGNED

In the proposed project "Entanglement-Assisted Thermoelectric Transport in Quantum Systems" (EATTS), the European Researcher Dr. Nahual Sobrino, together with Prof. Rosario Fazio at the International Centre for Theoretical Physics (ICTP), will collaborate with international research groups to unveil innovative thermoelectric properties that hold transformative potential for sustainable energy technologies, quantum information science, and the development of advanced quantum materials. The project's objectives will concentrate on the exploration of thermoelectric phenomena mediated by entangled electrons across a variety of quantum systems. A comprehensive theoretical and computational framework will be established to explore and enhance thermoelectric performance in systems where electron entanglement plays a pivotal role. Cutting-edge calculations will be performed using sophisticated theoretical frameworks, including Quantum Master Equations (QME), Hierarchical Equation of Motion (HEOM), and quantum information techniques. This will guide to elucidate the intricate relationship between entanglement, system-environment interactions, and thermoelectric performance in Double Quantum Dots (DQD) and Cooper Pair Splitters (CPS) systems. Moreover, the project aims to extend the scope of Density Functional Theory (DFT) to access to entanglement measures in transport scenarios through the development of extensions of iq-DFT. This will facilitate a more efficient computational description of thermoelectric phenomena under the influence of entangled electrons. Additionally, the thermoelectric and entanglement characteristics of multiple diatomic molecules will be investigated by mapping the system into effective Hamiltonian models. The computational framework developed will advance our understanding and serve as a guide for experimental endeavors by selecting promising materials and parameter regimes.

Keywords: thermoelectric phenomena,entanglement,density functional theory,
Gender Equality Network to Develop ERA Communities To coordinate Inclusive and sustainable policy implementatiON (GENDERACTIONplus)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Reforming and enhancing the European R&I System
Destination: Reforming and enhancing the European R&I System
Action type: Coordination and support actions
Countries involved: Czechia,Sweden,Spain,Austria,Ireland,Romania,Germany,Israel,Norway,Poland,Lithuania,Portugal,Greece,Slovakia,Italy,Bulgaria,Türkiye,Denmark,Estonia,Belgium,Cyprus,Croatia,Malta,Netherlands,Slovenia
Call: Policy coordination to advance the implementation of the ERA gender equality and inclusiveness objectives within Member States (HORIZON-WIDERA-2021-ERA-01, 2021)
Start date: 2022-06-01
End date: 2025-05-31
Duration (months): 36.0
Total project cost (EUR): 3040246.07
EU funding (EUR): 2999814.0
Participants: 42
Project status: CLOSED

Building on the Horizon 2020 project GENDERACTION, the overall goal of GENDERACTIONplus is to contribute to the coordination of gender equality and inclusiveness objectives of the new European Research Area through the development of a policy community of practice consisting of national authorities from 11 MS and 2 AC and 7 MS Associated partners and an RFO community of practice from 8 MS and 2 AC and 9 Associated partners. The coordination network covers a total of 23 MS and 3 AC with 26 project partners and 18 Associated partners. Specifically, the project aims to: 1) Develop strategic policy advice on existing and emerging policy solutions in the key thematic areas (intersectionality and inclusiveness; gender-based violence; gender dimension in research, innovation and teaching; monitoring and evaluation of ERA gender equality actions; supporting institutional change through gender equality plans); 2) Enhance the policy-making process through engaging with stakeholders, CSOs and citizens; 3) Build capacities, competence and expertise for gender equality and mainstreaming in R&I among the policy and RFO community members, with special attention to countries with a less comprehensive policy; 4) Create impact through communication, dissemination and exploitation, including national impact plans and an EU impact plan, policy briefs and position papers based on the policy advice developed. The impact of GENDERACTIONplus will be: 1) Advanced policy coordination among MS and AC and through stakeholder and citizen engagement; 2) Improved research careers and working conditions in European R&I, by developing policy dialogue and solutions on inclusion and intersectionality, combating gender-based violence and promoting institutional changes through GEPs; 3) Increased research quality and social responsibility of knowledge through the integration of gender dimension in R&I; and 4) Reduced geographic inequality by targeting less experienced/engaged countries and regions.

Keywords: public policy,research and innovation,era,gender equality plans
Resilient Trust- Trusted SMEs for Sustainable Growth of Europeans Economical Backbone to Strengthen the Digital Sovereignty (Resilient Trust)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Public-private partnerships
Destination: Chips for Europe Initiative
Action type: Research and Innovation actions
Partnership: CHIPS (JU-JTI)
Countries involved: Germany,France,Italy,Netherlands,Sweden,Switzerland
Call: General according to ECS-SRIA 2022 (RIA) (HORIZON-KDT-JU-2022-2-RIA, 2022)
Start date: 2023-10-01
End date: 2027-05-31
Duration (months): 44.0
Total project cost (EUR): 16680116.21
EU funding (EUR): 5468608.54
Participants: 32
Project status: SIGNED

The internet of things (IoT) is promising as it drives the datafication of our everyday life and thus, leverages synergies between originally considered “dead” things and enables them to proactively serve humans. IoT leads to a high automation potential with which we improve the life of billions of people and compensate for societal problems such as a growingly old population, missing high-skilled labour across Europe or the efficiency limits in current production capabilities. IoT5.0, an Artificial Intelligence (AI) -assisted Internet of Things, could even more benefit society, as the devices could even learn how to provide more value. But the ubiquitous connectivity comes at a cost. Security levels have to rise tremendously to ensure a network stays secure and safe for humans. This additional effort often is a burden for small and medium sized enterprises as the complexity and security demands of such systems rise faster than available resources. This is especially dangerous as a single corrupted, malicious device can result in the exploitation of the entire network of connected devices by an attacker. Consequently, RESILIENT TRUST focuses on end-to-end security of IoT processing chains with a focus on strong exploitation for SMEs. This vision will be realized by developing specialized hardware to establish TRUST in-between a network and a wall of RESILIENCE even against new attack methods such as post quantum attacks and AI based attacks. The architecture of the secure processing chain will be carefully built after threat modelling, asset identification, risk analysis, security objectives and requirements definition. Consequently, RESILIENT TRUST will address and significantly mitigate these major risks to enable IoT5.0. That way this project will be a driver for sustainable development and the generation of convenience and wealth. A solution is proposed to ensure end-to-end security by boosting RESILIENCE and TRUST along different key supply chains of IoT device

Keywords: ics secure and safe cpss by and for smes resilience prevent side channel attacks,pqc,ai based rf detection and mitigation,jamming trust hrot,puf,tee
Immunogenomic and ageing determinants of therapy response in brain metastasis (IMMUNAGENOMICS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Luxembourg
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1499980.0
EU funding (EUR): 1499980.0
Participants: 1
Project status: SIGNED

Cancer represents a critical public health issue, with 2.74 million new cases diagnosed in Europe in 2022. Most cancer-related deaths are attributed to metastatic spread and it is estimated that 20-40% of all cancer patients will develop metastases to the brain (BrM), facing a dismal prognosis. Novel immunotherapies have shown promising outcomes in BrM patients, although a substantial proportion remain unresponsive. This reflects the heterogeneous nature of the tumor immune microenvironment (TIME) and emphasizes the need for a better understanding of its role driving pro- or anti-tumoral responses. My postdoctoral research suggested an important role for genetic variation in human BrM cancer cells regulating the composition and function of the TIME. Likewise, ageing has a major impact in the ability of the immune system to fight cancer. However, how these two key factors interact and influence responses to therapy remains unknown. IMMUNAGENOMICS aims to transform personalized care for BrM patients by offering a multidisciplinary view on the dynamic regulation of the TIME by ageing and genetic variation. Specifically, we will: (i) characterize changes in baseline immunity along ageing;(ii) evaluate responses to radio- and immunotherapy in young and aged mouse models of BrM bearing different somatic mutations; (iii) analyze the TIME of BrM tumors from young and aged mice, pre and post-treatment by complementary orthogonal approaches including: flow cytometry, hyperplexed immunofluorescence imaging, scRNA-Seq and spatial transcriptomics; (iv) examine the link between ageing, genetic variation, TIME phenotypes and responses to therapy in collections of banked human BrM samples. Overall, I envision that IMMUNAGENOMICS will help decipher the complex interplay between ageing and genomic variation shaping immune responses against BrM tumors, ultimately opening new perspectives for the development of more effective personalized therapies for this devastating form of cancer

Keywords: brain metastasis,tumor immune microenvironment,immunogenomics,ageing,immunotherapy
EUropean network for neurodevelopmental RASopathies (EURAS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Tackling diseases and reducing disease burden
Action type: Research and Innovation actions
Countries involved: Germany,Austria,Spain,Portugal,France,Finland,Netherlands,United Kingdom
Call: Development of new effective therapies for rare diseases (HORIZON-HLTH-2022-DISEASE-06-two-stage, 2022)
Start date: 2023-06-01
End date: 2027-05-31
Duration (months): 48.0
Total project cost (EUR): 8048715.25
EU funding (EUR): 8048715.25
Participants: 17
Project status: SIGNED

Cardio-facio-cutaneous syndrome, Costello syndrome and SYNGAP1-related encephalopathy are rare neurodevelopmental RASopathies manifesting with severe intellectual disability, seizures and autism spectrum disorder. These symptoms are underdiagnosed and lack approved therapeutic options. EURAS aims to develop new effective therapies and operative disease management for RASopathies. With strong support of patient organizations from 13 countries, a new patient report-based registry for stratification of patient cohorts and evaluation of treatments will be implemented. To clarify the pathophysiology of RASopathies and to identify cellular/molecular “disease signatures” as biomarkers for drug screening and for therapy validation, EURAS will generate new and employ existing disease models. Phenotypical screenings of drug libraries assisted by automated high-resolution, high-content pipelines will be conducted on differentiated, electrically active patient iPSC-derived neurons. Preclinical proof-of-concept trials with repurposed drugs, antisense oligonucleotides and motor-cognitive training will be performed to achieve reversal of seizures and autistic behavioural traits in animal models. To provide patients with less invasive treatments, new technologies for efficient drug delivery of treatments to the brain will be developed and validated. Finally, EURAS establishes Europe-wide patient association to improve awareness and exchange between affected families and to foster their access to knowledge and therapies. With all these measures, EURAS delivers new effective therapies and set the frame for early and accurate diagnosis of neurological symptoms in RASopathies, which are not available at present. Moreover, some results of EURAS will be widely transferable, fostering development of therapies even for unrelated diseases. Thus, EURAS will sustainably improve the lives of affected people and strengthen expertise of health systems in Europe and worldwide.

Keywords: rasopathies,syngap1,synaptopathy,neuronal plasticity,disease modelling,induced pluripotent stem cells ipscs,animal models,epilepsy,autism,neurodevelopmental diseases,drug repurposing
Circular X Accelerator (CXA) (CXA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Netherlands
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-09-01
End date: 2027-02-28
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Advanced circularity strategies including sufficiency (reuse, refuse) and regeneration have not yet scaled up in business practice. More support is needed to accelerate this transition. The goal of the Circular X Accelerator (CXA) is to develop and scale advanced circular business models. Such business models have the potential to achieve significant environmental impact improvements compared to simply selling products. ERC Circular X pioneered research on experimentation with advanced circular business models. The project developed 3 open access databases covering over 300 business examples, focused on (1) circular business model experimentation, (2) sufficiency and (3) regeneration in business, plus several circular business tools tested and used by business, such as the “Circular Experimentation Workbench”, “Road Ahead Tool” and “Circular Rebound Tool”. These tools and databases are brought together into a “circular business experimentation lab approach”. Advancing the lab idea, the aim of this Proof of Concept (PoC) project is to develop the CXA as an ongoing entity, to be tested in the PoC. The CXA aims to accelerate the uptake of advanced circular business models in business practice, which includes regenerative and sufficiency-oriented business approaches and scaled up approaches. The PoC project will therefore investigate, test and validate the CXA approach in different settings with 5 Work Packages: 1. Investigate the appetite for advanced circular business tools with different user groups in different context 2. Investigate the best knowledge transfer strategy for advanced circular business innovation approaches. 3. Identify the strengths, weaknesses, opportunities and threats of the CXA 4. Clarify the competitive positioning of the CXA 5. Determine the best form and potential partnerships for the CXA. Advanced circular business innovations are not sufficiently scaled. The CXA will be scrutinised as a vehicle to accelerate these topics in practice.
Leveraging Languages: Professional Opportunities in the Early Modern Language Sector (1550-1650) (LangPro)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Netherlands
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1499996.0
EU funding (EUR): 1499996.0
Participants: 1
Project status: SIGNED

Historians have shown that the period from 1550 to 1650 was marked by a rapid expanse of the print industry, language education, and administrative bureaucracy, especially in North-West Europe. This implies that there must have been a swift increase in occupational opportunities for men and women who possessed language skills such as reading, writing, and text editing in one or more languages. However, since language professionals have never been studied as a separate category in the early modern workforce, the opportunities that existed for linguistically skilled individuals remain a big unknown. LangPro adds a fundamental missing perspective to our understanding of the early modern labour market by introducing the new notion of the language sector: that part of early modern economies which relied primarily on language skills. The project considers language proficiency as a hard skill with real-world professional value. LangPro’s central research question is: What professional, financial, and social opportunities did the early modern language sector offer to men and women in early modern North-West Europe (1550-1650)? Five work packages will disclose the potential for personal advancement that the language industry offered: financial income; support through a guild system; enhanced social status; and job opportunities, specifically for women. Laying the groundwork for a new research domain on the history of the language sector, we will develop a conceptual framework and prosopographical database that make it possible to gain insight into the characteristics of professionals in the past whose core business was language and the nature of the sector that employed them. LangPro will evoke important shifts in the history of early modern labour, women’s history, and the history of language practices. It is the forerunner of a new research line on a long underestimated sector that provided precious opportunities to individuals from all walks of life.

Keywords: language sector language professionals language skills multilingualism literacy early modern period north west europe labour history language history women s history guilds
TOWARDS A WIDE-SPREAD HVDC-BASED POWER SYSTEM ENABLED BY NEW HIGHLY EFFICIENT CABLE & FIBRE OPTIC MONITORING SYSTEMS (EasyDC-FOS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Sustainable, secure and competitive energy supply
Action type: Research and Innovation actions
Countries involved: Spain,Norway,Germany,Denmark
Call: HVAC, HVDC and High-Power cable systems (HORIZON-CL5-2024-D3-01, 2024)
Start date: 2024-09-01
End date: 2027-08-31
Duration (months): 36.0
Total project cost (EUR): 7558844.42
EU funding (EUR): 5499281.22
Participants: 13
Project status: SIGNED

Towards a dominant renewable energy generation scenario in the EU, it is key to modernise transmission systems for an efficient transport of the energy produced. The deployment of HVDC systems plays a crucial role in enabling electricity transmission over long distances with minimal losses. There is the need to bring new cable technologies that can increase the life cycle of future HVDC systems, and longer reach, more precise, easy to install sensor-based technologies to analyse cable status and locate potential faults. EasyDC-FOS project will commit to demonstrating a new generation of HV cable systems with optimised energy transport capability and longer life period, due to the use of an alternative XLPE insulation material, paired with the development of a series of smart tools for monitoring ageing and efficient fault detection in transmission networks, and reaching a TRL5 by the involvement of 3 demonstrators, 1 test bench and 2 real-world use cases, in different EU countries. This will be achieved by the: 1) optimisation of insulation materials for HVDC cables with operating temperature over 90ºC; 2) development of predictive models of physics and ageing behaviour of new cable system in response to thermal, acoustic and electric field stress stimulus; 3) prototyping of a set of fibre-based DTS, DAS, point vibration, and PD monitoring systems for long-distance cable corridors; and 4) integration into a cybersecure Edge Infrastructure that will allow real-time monitoring of cable conditions, as well as immediate response from TSOs, satisfying the KPIs in terms of system efficiency and stability, lifetime and thermal capacity assessment, and the accuracy of the sensors. For that purpose, EasyDC-FOS is bringing together a wide experienced consortium led by LMK, involving leading industrial technology developers of cables systems, a cable OEM, academic institutions, two TSOs, a key sector association, and sustainability and management experts at European level.

Keywords: hv,hvdc,alternative xlpe,new cable prototype,fibre based fault location systems,predictive cable management,edge infrastructure,cybersecurity