Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Helios- Automated 3D Priniting System for Zero - Emission Construction with Hempcrete - Based Filaments (HELIOS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Poland
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2499000.0
EU funding (EUR): 2499000.0
Participants: 1
Project status: CLOSED

Neodynsmics is a Polish deep-tech company developing Europe’s first 3D printing ecosystem for sustainable house construction based on hempcrete composite filaments. Our breakthrough technology combines a large-scale automated 3D printer (up to 7m height), a proprietary bio-based construction material (hemp-lime filament), and intelligent BIM-integrated software – enabling fast, zero-emission, cost-efficient building with minimal labor needs. The construction sector is under pressure to decarbonize while facing rising material costs, skilled labor shortages, and a growing housing crisis. Existing 3D printing solutions rely on cement-based mixes, contributing heavily to CO2 emissions and failing to meet EU insulation standards without additional layers. Neodynamic’s system – code-named HELIOS – delivers: up to 60% faster construction, >40% reduction in structural costs, ~85% lower CO2 footprint per m² of wall compared to cement, full compliance with the EU Green Deal and EPBD 2028 requirements. The solution is TRL6, validated in operational conditions, with a 1:1 prototype tested and patent-pending (EUIPO). Our market entry strategy focuses on early adopters: housing developers, municipalities, and prefab manufacturers seeking carbon-neutral, scalable alternatives. We are applying for EIC Accelerator support (€4.7M blended finance) to complete CE certification (TRL9), scale production, and commercialize by 2027. Our vision: to democratize ecological housing by making plug-and-print zero-emission homes available across Europe – faster, greener, and cheaper than concrete.

Keywords: 3d printing construction technology hempcrete zero emission housing sustainalable building green construction
The last formation: dating recrystallisation events of evaporites using lyoluminescence (Lyoluminescence)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Germany
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-04-01
End date: 2025-03-31
Duration (months): 24.0
Total project cost (EUR): 189687.36
EU funding (EUR): 189687.36
Participants: 1
Project status: CLOSED

Sufficient knowledge of the timing and dynamic of Quaternary (last 2.58 million years) climate phases through palaeoenvironmental studies is indispensable for accurate risk assessment and decision-making towards climate resilience of our modern societies. Geochronological frameworks are the backbones of such studies, and new and innovative chronological tools can further boost their impact and value towards a better adaption to climate change. Our project, Lyoluminescence, is about innovation in geochronology designed to contribute to the mission goals of Horizon Europe: “Adaption to Climate Change”. Lyoluminescence is the emission of light while dissolving a previously irradiated solid (such as sodium chloride) into a liquid solvent (water) due to the production of free radicals in the solution. The amount of light increases proportionally with the radiation dose absorbed by the material after crystallisation. Therefore, the process is a suitable candidate to be exploited as a dating method. The signal resetting through dissolution and recrystallisation renders lyoluminescence a potentially dating tool for the last 10 thousand to 5 million years. The aim of this project is the breakthrough development of lyoluminescence as a dating tool on salts (sodium chloride and potassium chloride) for application in geography & Earth sciences. We hypothesise that lyoluminescence naturally occurring in salt minerals such as halite and sylvite will allow dating the last recrystallisation event beyond the age limits of conventional luminescence-dating methods and that these features can be exploited for routine use in Quaternary geochronology. Our project will (1) design, develop and test a new portable lyoluminescence reader, (2) apply the newly developed device to natural salt sites to develop dating protocols and analysis routines, and (3), if successful, map out a commercialisation plan. The project will be hosted at the Ruprecht-Karl University of Heidelberg, Germany.

Keywords: luminescence dating,geochronology,method development
Neural circuits for social communication (SOFTCHIRP)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Neuroscience and Disorders of the Nervous System
Panel description: Nervous system development, homeostasis and ageing , nervous system  function and dysfunction , systems neuroscience  and modelling , biological basis of cognitive processes and of behaviour, neurological and mental disorders – In humans and all other organisms
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-07-01
End date: 2027-06-30
Duration (months): 60.0
Total project cost (EUR): 1500000.0
EU funding (EUR): 1500000.0
Participants: 1
Project status: SIGNED

The main objective of this proposal is to understand how vocal communication is used to organize social groups and in turn how brain circuits have evolved to process social information encoded in vocal cues. The naked mole-rat, as one of only two eusocial mammals, is especially well-suited to this research question. Naked mole-rats form highly cooperative social units and like bees, wasps, and ants, live in multigenerational colonies under the control of a single breeding female, queen. In addition to their extreme cooperativity, these rodents are highly vocal with a repertoire (greater than 25 distinct vocalizations) comparable to that of non-human primates. I recently identified that naked mole-rat greeting calls, soft chirps, encode information about individual identity and are modulated to create distinct colony-specific dialects. Vocal dialects can be learned early in life and are influenced by social cues (i.e., the presence or absence of the queen). These features position the naked mole-rat as a promising, yet unexplored model for investigating the evolution of neural circuits for vocal communication, sociality and language. I will employ a combination of behavioral, computational, electrophysiological, molecular and in vivo imaging tools to investigate how: (i) social identity is encoded at the earliest stages of auditory processing within the naked mole-rat brain, (ii) how neural circuits for vocal production are shaped by auditory environments during development and finally (iii) how social interactions acting through transcriptomic and molecular mechanisms influence vocal behaviors. This work has the potential to not only expand our understanding of the neural architecture underling the sensory coding and production of vocalizations, but also to provide insights into complex social behaviors such as empathy and altruism.

Keywords: acoustic communication,social behavior,naked mole rat,cortex,vocal behavior
Powerplant Hybrid Application for REegional Segment (PHARES)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Aviation
Action type: Innovation actions
Partnership: CLEAN-AVIATION (JU-JTI)
Countries involved: Canada,Poland,France,United Kingdom,Belgium,Italy,Netherlands,Germany
Call: Demonstration of a Hybrid-Electric Propulsion System for Regional aircraft, including Pylon and Nacelle Integration and modification (HORIZON-JU-Clean-Aviation-2025-01, 2025)
Start date: 2026-01-01
End date: 2030-12-31
Duration (months): 60.0
Total project cost (EUR): 101742587.5
EU funding (EUR): 69026926.64
Participants: 12
Project status: SIGNED

The PHARES project will accelerate and de-risk the entry into service of hybrid-electric ultra efficient regional aircraft by 2035. PHARES will mature and validate an advanced thermal engine (building on the PW127XT), an advanced propeller system and a hybrid-electric propulsion system (HEPS) in close alignment with physical integration and aerodynamical optimisation of pylon, nacelle and associated systems. In doing so, PHARES will contribute to no less than 20% of the 30% CO2 emission reduction target set out in SRIA and being fully compatible with sustainable aviation fuel. It will mature hybridisation technology to TRL5 and lay ground for its TRL progression to TRL6 via flight test demonstration in REG-03, presenting a significant steppingstone for EIS by 2035 and the vision of reaching “zero-carbon” aircraft in 2040+. To achieve its ambitious targets, the PHARES project brings together global key stakeholders of the aviation industry (airframer, OEMs, tier 1 suppliers) as well as leading RTOs, leveraging relevant synergies from national and European programmes. Teaming up with ACI-01, REG-02 and REG-03 winners, PHARES will maximise the probability of success for an EIS in 2035 and drive certification readiness to CRL5, with a clear roadmap to CRL6. Significant experience from programmes such as the Canadian HEP demonstrator, longstanding collaboration of experienced OEMs with known and reliable platforms and an excellent consortium will ensure that PHARES will achieve its targets and contribute both to the achievement of the environmental target for ultra-efficient regional turboprop aircraft and to the strengthening of European leadership in the aviation sector.

Keywords: hybrid electric propulsion system,thermal engine,integrated powerplant,propeller,controls,nacelle,saf,certification readiness,ground test,flight test demo,regional aircraft,flight test
Direct pathogen identification at the Point of Care (NOSTICS)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Netherlands
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Nostics aims to revolutionize infection management with its cutting-edge point-of-care (PoC) diagnostic platform. The primary objective is to address the slow, costly, and often inaccurate current diagnostic methods for infectious diseases. Nostics’s solution leverages Surface Enhanced Raman Spectroscopy (SERS) to provide rapid, lab-quality results within minutes at the PoC. This technology enables healthcare professionals to make timely, informed treatment decisions, reducing unnecessary follow-up visits and hospitalizations. To achieve this, Nostics will develop and validate a prototype integrated with advanced SERS technology, initially targeting urinary tract infections (UTIs) and expanding to sexually transmitted infections (STIs) and respiratory tract infections (RTIs). The project involves advancing the platform through clinical evaluations, regulatory certification, and strategic commercialization. The proposal aligns with the work programme’s focus on improving healthcare outcomes through innovative diagnostics. It addresses the need for effective infection management, supports antibiotic stewardship, and contributes to global health policies and UN Sustainable Development Goals. The project will significantly enhance patient care, reduce healthcare costs, and offer a scalable solution for a broad range of infections. EIC support is essential for de-risking and scaling this transformative technology, which will benefit a large patient population worldwide.

Keywords: point of care,urinary tract infections,sexually transmitted diseases,respiratory tract infections,antimicrobial resistance
A novel synthetic data generation platform that produces private, secure and robust synthetic data for AI use cases (SydAi)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

The age of the artificial intelligence (AI) revolution has arrived, bringing with it numerous opportunities across key industries, including healthcare, banking, and retail. Recent studies indicate that AI has the potential to increase global GDP by USD 15.7 trillion by 2030. However, the effectiveness of AI systems has thus far been limited by a lack of access to high-quality data without infringing on privacy rights. Poor data quality—characterized by incompleteness, inaccuracies, outdated information, or irrelevance—can lead to biased predictions and erroneous decisions, affecting up to 80% of AI projects. To address these issues, synthetic data has emerged as a potential solution. Synthetic data is artificially generated information that mirrors the statistical properties of real-world data. This data can be freely processed and used in AI model development without risking privacy breaches. However, until synthetic data can overcome its current limitations, its use remains restricted. These limitations include avoiding biases present in the original data, generating synthetic data that mimics very complex relational databases, and effectively satisfying deterministic rules. At Aindo, we have developed SyDAi, a novel synthetic data platform that empowers companies to generate high-quality and high-privacy synthetic data. This breakthrough aims to democratize and accelerate AI innovation, enabling all industries to actively participate in the AI revolution. Unlike many existing solutions that focus on specific data types or lack the ability to handle certain statistical dependencies, our platform can generate synthetic data with advanced data formats. The innovation of this innovation has recently led to SyDAi being recognized independently by the United States National Institute of Standards and Technology (NIST) as best-in-class for optimizing the privacy-fidelity trade-off.

Keywords: generative artificial intelligence machine learning data synthetic data synthetic data platform synthetic data generation data fidelity
OCD and the Brain - a co-produced resource to understand brain research on OCD (OCDBrain)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Public Engagement with Research Award
Action type: Recognition Prize
Countries involved: Germany
Call: ERC-2024-PERA (ERC-2024-PERA, 2024)
Total project cost (EUR): 0.0
EU funding (EUR): 0.0
Participants: 1
Project status: SIGNED

OCD and the Brain was an inter-disciplinary engagement project aimed to co-produce an engaging and interactive online resource for young people living with Obsessive-Compulsive Disorder (OCD) and their parents/guardians to share knowledge about the brain and OCD. This resource was conceived, developed and launched in collaboration between researchers (Prof Tobias Hauser & team), two leading OCD charities (OCD Action and IOCDF), the OCD community and public engagement specialists. Together, we have co-produced a unique resource conveying complex neuroscience in an accessible way, tailored to needs and experiences of the OCD community. The project was created after initial consultation sessions with OCD stakeholders revealed a stark disconnect between neuroscience research and the OCD community. In a series of online creative workshops, led by creative facilitators, young people living with OCD, their parents and OCD researchers exchanged experiences and explored questions and ideas about the brain’s role in OCD. Insights from the workshops formed the basis of the resource, which was further developed in the second project phase. Through focus groups with members of the OCD community, the two charities, researchers and a creative design studio, this co-development phase focused on iteratively developing all aspects of the resource, including the content, style, user-experience, visuals and overall tone, ensuring its accessibility and relevance to both young people and adults. The resulting website, www.ocdandthebrain.com, was launched at an international livestream event and has since seen a tremendous uptake in a worldwide community. Moreover, this truly collaborative project has directly influenced the researchers’ work, leading to co-produced grant applications and new research projects, which directly address the OCD community’s interests and needs.

Keywords: neuroscience,mental health,obsessive compulsive disorder ocd,co production,psychoeducation,stigma
Preclinical in vivo proof-of-concept for cyclic oligopeptide rescuers of pathogenic protein misfolding and aggregation associated with neurodegeneration (PoC4ProMis)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Greece
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-09-01
End date: 2026-02-28
Duration (months): 18.0
Total project cost (EUR): 214285.71
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Within the ERC Consolidator Grant ProMiDis, my team and I have developed genetically engineered bacteria that function as a stand-alone, living discovery platform for short, drug-like cyclic peptides rescuing the misfolding and aggregation of proteins associated with human diseases (protein misfolding diseases, PMDs). By applying this technology, we have discovered hundreds of new molecules-putative drugs against notorious PMDs, such as Alzheimer’s disease and amyotrophic lateral sclerosis (ALS). We have filed patent applications for aspects of this technology and for the first set of bioactive molecules. In PoC4ProMis, we will demonstrate in vivo proof-of-concept for the most promising molecules targeting the devastating neurodegenerative disease ALS. To achieve this, we will first develop an optimized method for efficient delivery of cyclic peptides to the central nervous system (CNS) by utilizing a novel specialized CNS delivery vehicle. Then, we will evaluate the effectiveness of our lead molecules to reverse disease phenotypes in well-established ALS mouse models. Finally, we will explore opportunities to strengthen further our IP portfolio by patent-protecting our SOD1-targeting cyclic peptides with additional claims relating to method-of-use and mode of delivery. PoC4ProMis will demonstrate in vivo PoC and will provide a general approach for efficient CNS delivery of cyclic peptide drugs targeting additional neurodegenerative diseases of high priority for drug development.

Keywords: protein misfolding and aggregation,sod1,als,neurodegeneration,preclinical development
Exploring the Ethics of AI for Global Development (EAI4GD)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Ireland,Uganda
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 252728.64
EU funding (EUR): 252728.64
Participants: 2
Project status: SIGNED

Artificial Intelligence (AI) offers a new way to approach the seemingly intractable challenges of Global Development, mobilising unprecedented amounts of data and generating insights from previously unused sources (e.g. big data, mobile phone records). Unlike traditional development projects, AI systems can scale rapidly while requiring very little on-the-ground implementation. However, the ethical implications of incorporating AI into Global Development are not well-defined. Therefore, this project seeks to collect empirical data about the ethical questions that arise when AI is part of a development project. It will involve a case study of the AI Cookstoves Project, an on-going collaboration between the ADAPT Centre in Ireland and Makerere University in Uganda. The AI Cookstoves Project takes a familiar problem - the use of woodburning cookstoves - and approaches it with a combination of engineering, community input, and AI-generated design suggestions. In doing so, it raises ethical questions about development and AI, including whether the goal of energy efficiency for the stoves is outweighed by the energy costs of running a generative AI model, and how the inclusion of AI models affects the knowledge hierarchy among stakeholders with different kinds of knowledge. At the same time, the researcher will seek to understand how AI and Global Development experts conceive of the potential for AI in development through in-depth interviews of experts and participant observation at public presentations and working group discussions about AI, ethics, and global development, in Ireland and Uganda. This work brings a distinctly global lens to the question of AI ethics. In this way, it aims to speak to the Sustainable Development Goals for inclusive economic growth (#8) and reduced inequality (#10). It also seeks to provide policymakers with a new approach to AI ethics that is grounded in actual examples of AI in practice.

Keywords: global development