Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Crosspoint In-memoRy CompUting Systems (CIRCUS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Panel: Systems and communication engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Italy
Call: ERC Proof of Concept Grant (ERC-2018-PoC, 2018)
Start date: 2019-05-01
End date: 2020-10-31
Duration (months): 18.0
Total project cost (EUR): 149463.75
EU funding (EUR): 149463.75
Participants: 1
Project status: CLOSED

Every second, our smart phones deliver a wealth of information that can be used to monitor the traffic, the financial transactions, and even the spread of a dangerous disease. The processing of these big data into a meaningful information requires specific machine learning (ML) algorithms, which essentially consist of regression techniques for inference, classification and prediction. The conventional digital computers are not designed to optimally solve these problems with efficient time and energy consumption, which is one of the reasons why the power consumption by data centers worldwide is expected to triple in the next decade. Such a poor energy efficiency is essentially due to the physical separation between the central processing unit (CPU), where data are computed, and the memory, where data are stored, according to classical von Neumann computer architecture. In the frame of our ERC-CoG RESCUE, my group has developed a new paradigm to efficiently execute ML tasks in just one step within the memory. Instead of moving data from the memory to the digital CPU, an analogue computation is directly operated within the data, thus breaking all previous limits of time and energy consumption (10.000x reduction in the number of operations, hence time, and 1.000x in energy). Our in-memory technology is modular and universal, thus can be implemented in any existing memory and computing technology to accelerate ML tasks in future smartphones and data centers. In the ERC-PoC CIRCUS, we aim at bringing this technology to a higher maturity level, demonstrating its scalability and technical feasibility by simulations and realization of a small-scale prototype. In the meantime, we will also perform a comprehensive market search to recognize opportunities and draft an investor-ready business plan for raising future investments to further advance the solution toward industrial exploitation.

Keywords: big data,machine learning,artificial intelligence,in memory computing,deep learning,one shot learning,crosspoint arrays,emerging memories,analogue computing,approximate computing,physical computing,data analytics,linear regression,page rank,machine learning accelerators
Rotative Cylinder Compressor for energy efficient industrial compression process (CCR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Spain
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2018)
Start date: 2019-01-01
End date: 2019-06-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

Gas compression with piston reciprocating compressors dates from 19th century and it is widely used today for a vast range of industrial applications. The process of compression is energetically inefficient as just ten percent of the energy consumed becomes mechanical energy as compressed gas, being the rest of the energy wasted in heating the gas, energy that must be dissipated incurring an additional energy expenditure. ABC COMPRESSORS has developed the Rotating Cylinder Compressor (CCR – Compresor Cilindros Rotativos) which adopts a disruptive concept of piston compression based in centrifugal forces. This new compressor concept enables to reduce up to 20% the energetic consumption of compressors eliminating the need of water cooling and reducing considerably the dimension (and constructive cost) of the compressor. Oil and Gas market is outlined as principal market for this project due to the big size of the market (around 50% of global compressors), growing trends, and market pressure for reduce energy consumption. More than 10.000 compressors are sold nowadays, and it is expected to have a steadily growth due to natural gas plants proliferation and old compressors replacing market in Europe and US. Taking into account existing needs, potential market, ABC COMPRESSORS` strength and knowledge in high pressure compressors and industrial markets and the possession of patented superior technology (reduction of energy consumption, reduction of price and simplicity), a clear business opportunity for ABC COMPRESSORS is outlined. In this Phase 1 project, a feasibility study will be held to analyse the viability of the whole project, analysing market, product, business and financial features in order to guarantee the profitability of the investment in the identified markets and future scenarios.

Keywords: compressor,compression,efficiency,energy,rotative,cylinder,piston,centrifugal
A unified drug discovery platform for protein misfolding diseases (ProMiDis)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Biotechnology and Biosystems Engineering
Panel description: Biotechnology using all organisms, biotechnology for environment and food applications, applied plant and animal sciences, bioengineering and synthetic biology, biomass and biofuels, biohazards
Countries involved: Greece,Greece
Call: ERC Consolidator Grant (ERC-2018-COG, 2018)
Start date: 2019-03-01
End date: 2024-02-29
Duration (months): 60.0
Total project cost (EUR): 1972000.0
EU funding (EUR): 877327.86
Participants: 2
Project status: SUSPENDED

It is now widely recognized that a variety of major diseases, such as Alzheimer’s disease, Huntington’s disease, systemic amyloidosis, cystic fibrosis, type 2 diabetes etc., are characterized by a common molecular origin: the misfolding of specific proteins. These disorders have been termed protein misfolding diseases (PMDs) and the vast majority of them remain incurable. Here, I propose the development of a unified approach for the discovery of potential therapeutics against PMDs. I will generate engineered bacterial cells that function as a broadly applicable discovery platform for compounds that rescue the misfolding of PMD-associated proteins (MisPs). These compounds will be selected from libraries of drug-like molecules biosynthesized in engineered bacteria using a technology that allows the facile production of billions of different test molecules. These libraries will then be screened in the same bacterial cells that produce them and the rare molecules that rescue MisP misfolding effectively will be selected using an ultrahigh-throughput genetic screen. The effect of the selected compounds on MisP folding will then be evaluated by biochemical and biophysical methods, while their ability to inhibit MisP-induced pathogenicity will be tested in appropriate mammalian cell assays and in established animal models of the associated PMD. The molecules that rescue the misfolding of the target MisPs and antagonize their associated pathogenicity both in vitro and in vivo, will become drug candidates against the corresponding diseases. This procedure will be applied for different MisPs to identify potential therapeutics for four major PMDs: Huntington’s disease, cardiotoxic light chain amyloidosis, dialysis-related amyloidosis and retinitis pigmentosa. Successful realization of ProMiDis will provide invaluable therapeutic leads against major diseases and a unified framework for anti-PMD drug discovery.

Keywords: protein misfolding,protein aggregation,protein misfolding disease,synthetic biology,drug discovery,escherichia coli,cyclic peptides,huntington s disease,amyloidosis,retinitis pigmentosa
MDO and REgulations for Low-boom and Environmentally Sustainable Supersonic aviation (MOREandLESS)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Spain,Italy,Italy,Belgium,Greece,Sweden,Belgium,Romania,France,France,Netherlands,United States,United Kingdom
Call: Towards global environmental regulation of supersonic aviation (H2020-MG-2020-SingleStage-INEA, 2020)
Start date: 2021-01-01
End date: 2024-12-31
Duration (months): 48.0
Total project cost (EUR): 6336211.25
EU funding (EUR): 4999996.25
Participants: 17
Project status: SIGNED

MORE&LESS addresses the challenge of contributing to help Europe shape, together with the international community, high environmental standards in line with ICAO Assembly Resolution A39-1, by a thorough and holistic analysis of the environmental impact of supersonic aviation. MORE&LESS aims at maintaining a high level of citizens' and environmental protection at local, regional and global levels, and supports the consequent establishment of regulations and procedures for the future supersonic aviation through solid technical bases. The scientific findings in the fields of aerodynamics, jet-noise, sonic-boom, propulsion, pollutant emissions and environmental impact are in fact transposed into guidelines for the Regulatory Community. Through low and high-fidelity modelling activities and test campaigns, already accepted and validated software tools are enhanced and extended to cover supersonic aviation, to be eventually integrated into the multidisciplinary holistic framework. The application of this framework to the case-studies is the proving ground to verify that the enabling technologies of supersonic aircraft, trajectories and operations comply with the environmental requirements. The case-studies cover the entire spectrum of supersonic speed regime and include the most promising aircraft configurations, propulsive technologies and alternative fuels, such as bio-fuels and liquid hydrogen. MORE&LESS fosters international cooperation, thus paving the way towards the definition of global and internationally agreed regulations, while contributing to maintain world-class knowledge and skills in Europe in the field of supersonic aviation. MORE&LESS targets the engagement of new generations of students, scientists and engineers to inspire and challenge them to build and manage the environmentally sustainable supersonic aviation of the future.

Keywords: biofuels and liquid hydrogen,modelling activities and test campaigns for jet noise,sonic boom,combustion,pollutant emissions,multidisciplinary holistic framework with accepted and validated tools
Sustainable Materials for development of Advanced Renewable Technologies for the next generation solar CELLs (SMARTCELL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Career Restart panel
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-08-01
End date: 2024-07-31
Duration (months): 36.0
Total project cost (EUR): 304724.16
EU funding (EUR): 304724.16
Participants: 1
Project status: CLOSED

Solar photovoltaics (PV) is a leading candidate for the renewable, carbon-free electricity generation with both the scalability and technological maturity to meet the ever-growing global demand for energy. While PV module costs continue to decline rapidly, further system-level cost reductions will require lightweight, sustainable, and flexible module designs that are still inaccessible with today’s mainstream technologies. SMARTCELL proposes an innovative PV technology based on zinc phosphide (Zn3P2), an earth-abundant, low-cost, direct bandgap semiconductor for development of novel ultra-thin solar cells. SMARTCELL will implement novel technological solutions based on advanced nanofabrication methods for synthesis of high crystal quality zinc phosphide, which together with design and optimization of the device interfaces and the cell architecture will lead to achievement of a challenging increase in the device efficiency of up to 15 % at the cell level. These efficiencies will allow initiating the transfer of zinc phosphide based solar cells to pre-industrial stages and give SMARTCELL the opportunity to demonstrate scalable, cost-effective, and environmentally-friendly ultrathin-film PV technology. The working principle of SMARTCELL is based on a holistic interplay between first-principle calculations, synthesis conditions, and atomic-resolution structural and electronic characterization techniques, which will allow cutting-edge engineering of absorber properties, as well as the design of the solar cell architectures. Moreover, an integrated, flexible methodology will keep this target breakthrough in sight. Finally, SMARTCELL has the potential to make a key science-based contribution to energy security, as well as improved societal perception of green energy production.

Keywords: thin film solar cells,earth abundant materials
Cracking the Nucleo-Olivary Code (CraNOC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-03-01
End date: 2018-02-28
Duration (months): 24.0
Total project cost (EUR): 165598.8
EU funding (EUR): 165598.8
Participants: 1
Project status: CLOSED

For animals and humans to be successful in their environments, their motor and cognitive behavior must be adjusted to the constantly changing reality at a millisecond-timescale. For example, it is fairly simple for a brain to determine which muscles need to be activated to catch a falling object, but much harder to determine when and for how long. Without correct timing of the executive brain functions, as happens in some neurological disorders, the individual is unable to produce smooth and accurate movements and will also have difficulties with a range of cognitive functions requiring orchestration of distinct mental operations. The tripartite olivo-cerebellar system (OCS), which is formed by the inferior olive (IO), cerebellar cortex (CCTX) and cerebellar nuclei (CN), is considered critical for generating proper timing for many motor and cognitive operations. Interestingly, all three areas, IO, CTX and CN, have intrinsic oscillatory properties and together they constitute a reverberating microcircuit, beating with well-timed responses to requests from the sensorimotor system. The ultimate timing of the output of this system, by which it imposes its effects upon the rest of the brain, is mediated by the CN. Indeed, decades of research on the OCS has resulted in detailed concepts as to how it may generate and control computations with high temporal complexity. However, due to methodological difficulties the function of the nucleo-olivary (NO) pathway, which links the CN with the IO, has been neglected, hindering completion of the cerebellar theory. To crack the relevant temporal codes of this loop I have developed specific viral optogenetic tools that allow for targeted control of the NO pathway. Using them I will define the NO interactions that take place during behavior and learning, and examine how these interactions are perturbed in neurological disorders.

Keywords: brain,behavior,motor function,cerebellum,autism,optogenetics,timing
A European joint programming initiative to develop integrated, regional, smart energy systems enabling regions and local communities to realize their high sustainable energy ambitions (EN SGplusRegSys)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: ERA-NET Cofund
Partnership: EN SGplusRegSys (ERA-NET)
Countries involved: Austria,Spain,Ireland,Italy,Israel,Germany,Switzerland,Norway,Belgium,Belgium,Croatia,Hungary,Poland,Sweden,Türkiye,Romania,France,France,Netherlands,Denmark,United Kingdom
Call: ERA-NET Co-Fund Enhanced cooperation in Smart Local and Regional Energy Networks of the European Energy System (H2020-LCE-ERANET, 2017)
Start date: 2018-01-01
End date: 2023-12-31
Duration (months): 72.0
Total project cost (EUR): 36406227.79
EU funding (EUR): 12014055.18
Participants: 26
Project status: SIGNED

The action will set up a joint programming initiative to develop Smart, Integrated, Regional Energy Systems that enable regions and local communities to realize their high ambitions of moving towards decarbonised energy systems and at the same time link them to a secure and resilient European energy system. This shall include solutions that allow for a high proportion of renewables up to and beyond 100% in the local or regional supply. The initiative will coordinate relevant RDD programs in the involved European, associated countries and regions represented in the consortium connecting them with other funding and financing partners. It will accelerate the deployment of latest resource-efficient and decarbonising energy system solutions, thus strengthening the competitiveness in relevant markets and lerveraging sustainable structures already established by ERA-Net Smart Grids Plus . The latter is focussing on the broad involvement of a large number of countries and regions in order to implement European smart electricity grids research agendas, while the ERA-Net SG+ RegSys will build on this with a new approach, developing integrated, regional energy systems, including the full spectrum of energy carriers and infrastructures. A highly ambitious consortium will pilot new formats of collaboration with regional and local stakeholders as well as supply and demand side oriented technology policy.

Keywords: smart grids,energy systems,energy solutions,regional energy networks,heating networks,cooling networks,local utilities,start ups
Galileo Improved Services for Cadastral Augmentation Development On-field Validation (GISCAD-OV)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling exploitation of space data
Action type: Innovation actions
Countries involved: Italy,Italy,Spain,Germany,Belgium,France,France,Czechia,Netherlands,Canada
Call: EGNSS applications fostering societal resilience and protecting the environment (H2020-SPACE-EGNSS-2019, 2019)
Start date: 2019-12-01
End date: 2023-05-31
Duration (months): 42.0
Total project cost (EUR): 3361825.0
EU funding (EUR): 2606317.51
Participants: 14
Project status: SIGNED

GISCAD-OV involves the whole value chain of the Cadastral domain. It’s main scope is to design, develop and validate an innovative and cost-effective High Accuracy Service (HAS) for Cadastral Surveying applications, based on GPS+Galileo E6 HAS and Precise Point Positioning-Ambiguity Resolution (PPP-AR) quick convergence techniques. The project aims also to set up a GISCAD-OV Service Operator Centre, able to fully integrate the existing Augmentation and National infrastructures for improving Cadastral operations efficiency and effectiveness, reducing Cadastral procedures’ time for the benefit of the citizen. Furthermore, an efficient Cadastral System update process will improve the data reuse interoperability with other applications (Infrastructure Monitoring, post-disaster management). A Europe-wide Pilot Project campaign will be carried out for validating the implemented solution, applying single Countries Cadastral Regulations. GISCAD-OV is based on the following drivers: - Upgrade of commercial GNSS receivers for decoding and applying Galileo E6B corrections and integrating them into the PPP solution - PPP-RTK Multiple Constellation and Multiple Carrier Ambiguity Resolution and instantaneous fixing - Cost effective solutions, through the use of low-cost augmentation services and receivers, paving the way for “Smartphone Surveying” - Development of a Business Model and relevant revenue Mechanisms for a real implementation of a Cadastral HAS Business Plan, involving all relevant Value Chain Stakeholders a direct Commercialization GISCAD-OV targets the exploitation of new business opportunities in the Cadastral land surveying, through the service differentiation introduced by Galileo HAS corrections broadcasting. The current status of the above technologies falls in the area of TRL 6-7 while GISCAD-OV targets a TRL 8: System complete and qualified, including Galileo HAS implementation.

Keywords: cadastre,ppp ar,ppp rtk,nrtk,galileo,egnss,cadastral value chain
Artificial Intelligence powered epilepsy diagnostics (EPINOSTICS)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Finland
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 2687500.0
EU funding (EUR): 1881250.0
Participants: 1
Project status: CLOSED

65 million people globally suffer from epilepsy. The neurological disease causes significant suffering to patients and their caregivers, and its costs in Europe exceed €13 billion annually. Although efficient medications are available, they do not work for 30% of the patients who keep suffering from seizures due to the shortcomings of current epilepsy diagnostics methods. Neurologists need detailed data about seizures to select the best treatment for each patient, but current methods do not provide that data. Neuro Events Labs is developing an accurate, scalable and affordable solution called ‘Aida’ for epileptic diagnostics, providing neurologists with a comprehensive visual overview of the patients’ seizures. The Aida platform is based on a set of proprietary, patent-pending deep learning algorithms and latest camera technologies. Using these disruptive technologies, Aida detects seizure type, severity and length with unprecedented accuracy and reliability. The Aida prototype has been piloted in clinical at the Tampere University Hospital to select the best treatment and improve the quality of life of epilepsy patients with outstanding results. Neuro Event Labs is a venture-backed Finnish SME with a growth-oriented energetic team with extensive experience in building and scaling successful high-tech businesses. Our competences range from business development & sales to 3D cameras, artificial intelligence and neurology. The EPINOSTICS project allows us to develop capabilities of automatics detection and classification of all motor seizure types and deliver important health benefits globally. The unprecedented functionality allows us to capture a significant portion of the €6.5 billion annual market opportunity. The market is eager for new technologies because the existing methods do not provide satisfactory results.

Keywords: artificial intelligence,epilepsy diagnostics and treatment selection,all types of seizures