Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Vortices and waves: dynamics, stability and mixing (VORTEXETER)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-09-01
End date: 2013-12-01
Duration (months): 24.0
Total project cost (EUR): 200549.6
EU funding (EUR): 200549.6
Participants: 1
Project status: CLOSED

The proposal concerns the mathematical study of interactions of vortices, waves and mixing processes, in idealised models relevant to experiments and geophysical systems. Vortices, regions of rotating fluid, are common in the oceans and atmosphere, for example Gulf Stream rings and hurricanes, and in astrophysical systems, for example Jupiter's Great Red Spot. Such systems also support many kinds of waves, including inertial, Rossby and gravity, and the interactions of vortices and waves provide a rich variety of problems for mathematical and numerical study. Recent work of the group in Exeter has focused on vortex dynamics - purely two-dimensional fluid flow - in the absence of waves, and has quantified aspects of the stability of vortices, thresholds for the formation of structures such as tripoles, and development of vorticity staircases. There has been particular emphasis on linking the formation of structures to the stability of vortex profiles using the technique of tracking Landau poles. The aim of the proposal is to extend these studies by including surface gravity waves, using the so-called shallow water equations. The presence of such waves allows vortices to be destabilised by radiating away wave energy, and also allows vortices to be forced by streams of incoming waves. The research is focused on developing an understanding of stability, mixing and structure formation with these additional physical effects, which although idealised using a shallow water system, are an important aspect of many applications. The research programme involves a combination of asymptotic analysis and large-scale numerical studies, and is linked to recent experimental studies of Cobelli, Maurel, Pagneux and Petitjeans, in Paris. The proposed fellowship builds on the expertise of the researcher (in theory, experiment and numerics) and opens up opportunities for him to develop his career, by pursuing these new research directions in collaboration with the Exeter group.

Keywords: applied mathematics,fluid dynamics,hydrodynamics,vortex dynamics,stability,waves,mixing,partial differential equations
Building just and livable cities: Participation and contestation in neighborhood revitalization (URBLIV)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2011-06-15
End date: 2013-07-26
Duration (months): 24.0
Total project cost (EUR): 167180.8
EU funding (EUR): 167180.8
Participants: 1
Project status: CLOSED

Environmental justice (EJ) scholarship has revealed that communities of color and low-income neighborhoods have been disproportionally affected by 'brown' contaminating facilities and excluded from decision-making on their land. However, traditional EJ studies tend to overlook the fact that residents also fight proactively to achieve long-term equitable revitalization and improve the livability and environmental quality of their neighborhoods through parks, playgrounds, urban agriculture, fresh markets, and improved waste management. This project is built around a collaborative, comparative, and multidisciplinary study of three critical case studies of marginalized neighborhoods organizing for improved environmental and health quality in three cities – Barcelona, Boston, Havana. This research will further develop the nascent environmental justice scholarship in the European Research Area by focusing on how residents make proactive environmental and health claims, defend their vision for improved lasting neighborhood conditions, and address inequalities in environmental planning decisions in cities that encompass a variety of political systems and contexts of marginalization. It will also improve our understanding of how larger processes of urbanization, segregation, and land-use decisions have contributed to creating an identity in impoverished urban neighborhoods and later shaped mobilization. More broadly, this project will strengthen and broaden the fields of political ecology, urban sociology, and environmental governance in the European research community; it will create an international umbrella platform of expert scholars and NGOs working on achieving environmental justice and environmental governance in the United States and Europe; and it will contribute to the training of graduate students in environmental conflicts and environmental justice research, thus promoting scientific excellence and knowledge transfer to the European Research Area.

Keywords: urban and environmental sociology,public policy,governance and civic participation,urban geography,environmental policy and planning
Rechargeable Telemetry-Based Electrochemical Sensors: Kidney Oxygenation and health. (RETEBESKO)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Netherlands
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2011-06-01
End date: 2014-05-31
Duration (months): 36.0
Total project cost (EUR): 238119.2
EU funding (EUR): 238119.2
Participants: 1
Project status: CLOSED

Translational research for human health on major diseases such as cancer, cardiovascular disease, diabetes and obesity requires modalities that can monitor an ever widening spectrum of physiological signals over extended periods of time in animal models unhindered by anaesthesia or restraint. We hypothesize that a novel generation of in vivo rechargeable, telemetry-based electrochemical sensors will facilitate continuous recording of a hitherto uncharted spectrum of signals in different tissues and thereby will hugely improve testing and validation of new drugs as well as our understanding of physiology and pathophysiology. Elucidating the link between renal oxygenation and kidney health, will have major impact in the clinical practice, making it a very promising and timely subject. To allow such a breakthrough this proposal will start with the realisation of a telemetry-based solution for chronic measurement of oxygen in the kidney. This inherently multidisciplinary project will partner with the University of Auckland, a leading site in biomedical engineering, for the development and testing of novel telemetry devices. In acute experiments surgical methods and hardware will be refined and tested before progressing to experiments in conscious animals. Thereafter renal oxygen will be continuously recorded in an accepted rat model of chronic kidney disease without and with therapy to confirm disturbed oxygen homeostasis and to evaluate treatment efficacy. This fellowship will not only generate groundbreaking technology, knowledge and expertise to study kidney oxygenation, but it will also allow me to be at the forefront of a new area in physiology research. On my return to the home institute we will be able force breakthroughs within the European Research Area for mechanistic studies on hypoxia-dependent progression of kidney disease.

Keywords: physiology,biomedical engineering,nephrology
A Comparative Analysis of the Protection of Geographical Indications for Foodstuffs (PROGI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2011-09-01
End date: 2013-08-31
Duration (months): 24.0
Total project cost (EUR): 142113.2
EU funding (EUR): 142113.2
Participants: 1
Project status: CLOSED

The protection of geographical indications (GIs) for foodstuffs is a hotly debated question, both within the academic community and the political arenas. Even if GIs are unanimously recognized as part of the Intellectual Property domain, their proprietary dimension has been understudied so far, especially with regard to the fact they constitute a form of commonly-held property. My research proposal aims at filling this gap, combining comparative analysis with an interpretative account which explores the meanings, values and practices associated to this peculiar proprietary paradigm. Specifically, I will compare two legal systems which epitomize two different approaches: Europe and Canada. Indeed, while the first has created an ad hoc system for protecting the place of origin of foodstuffs centred on GIs, the latter has preferred to make recourse to more traditional tools, such as trademarks, employing GIs in a limited way. The research proposed outcome is to obtain a better understanding of: 1) which form of Intellectual Property GIs are; 2) which functions they perform, especially vis à vis other forms of IP. The second question seeks to connect the peculiar proprietary nature of GIs to the functions they perform, by asking whether such nature allows a better accomplishment of the three functions usually associated to them: 1. protection of the manufacturers’ investments in differentiating their products; 2. consumers’ information; 3. protection of cultural traditions and rural communities. The training I can receive at the outgoing and return host institutions would strengthen my research career, extending my expertise to a field at the crossroad between IP law and food law and acquiring important new methodological competencies on the use of an interpretative method of analysis in comparative law. The new skills and knowledge gained during the fellowship can be used both for conducting innovative and original research and for enriching my teaching.

Keywords: comparative law,intellectual property ? geographical indications,food law,international trade ? trips agreement ? protection of geographical indications
Electrocatalysis on Model Interfaces (ELCAMI)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2011-05-01
End date: 2013-04-30
Duration (months): 24.0
Total project cost (EUR): 187028.8
EU funding (EUR): 187028.8
Participants: 1
Project status: CLOSED

Low-temperapture polymer electrolyte membran fuel cells (LT-PEMFC) have been attracting great attention as a promising clean power generator. The primary reaction taking place at the cathode is the oxygen reduction reaction (ORR), which is traditionally catalysed by platinum. Commercialisation of the technology requires lower price, lower overpotential and higher stability of the electro-catalyst. The present proposal aims at exploring structure-reactivity correlations of four types of Pd-based model catalyst as base platforms for a rational ORR electro-catalyst design: (1) high and low index Pt(hkl) and Pd(hkl) single crystals; (2) Pt and mixed Pt-M (M= Fe, Co, Ni) films on Pd(hkl); (3) tailored Pt and Au nanoparticles on Pd(hkl); and (4) palladium-platinum alloy electrodes PdxPty of various composition and crystal orientation. Electrochemical reactivity studies will be combined with novel state-of-the-art in-situ imaging and spectroscopic techniques for monitoring local structure and reactivity. In particular, the applicant will employ in-situ Conductive-Probe Atomic Force Microscopy (CP-AFM) and the novel Raman spectroscopic technique SHINERS, capable for probing processes on well-definded single crystal surfaces under electrochemical operating conditions. This approach allows to explore in-situ the role of adsorbed intermediates as wll as spectators, such as OHads, anions, formation of surface oxides, and will provide unprecedented fundamantal knowledge on basic reaction mechanisms at nanoscale. The experimental work at Bern University will benefit from complementary DFT-type model calculations (collaboration with T. Jacob), and joined application studies with the technology-driven Electrochemistry Laboratory at PSI. The project also aims to build a strong connection of people, knowledge and skills between Europe and Japan for future collaboration.

Keywords: fuel cell technology,reaction mechanisms and dynamics,heterogeneous catalysis,electrochemistry
Extraordinary Laser-induced Excitations in Glasses: Analysis and Theory (ELEGANT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2011-10-10
End date: 2013-10-09
Duration (months): 24.0
Total project cost (EUR): 264436.8
EU funding (EUR): 264436.8
Participants: 1
Project status: CLOSED

The Project aims comprehensive experimental and theoretical studies of interaction of ultrashort laser pulses with optical glasses in order to reveal mechanisms of formation of extraordinary structures induced by laser radiation inside the bulk glass and to establish principles of controlled generation of desired glass modifications for applications in photonic devices. Optical glasses have become the key materials of optoelectronics and photonics applications due to their relatively low costs, processability, and possibility to govern refractive indexes. Recent research has shown that, applying femtosecond laser pulses to glass materials, one can create three-dimensional patterns with nano-scale features whose origin has not yet been understood. These findings can open new opportunities for a broad variety of microsystems with nanofeatures. However, further development of laser-writing techniques for controllable generation of desired modifications in transparent materials is impossible without deep understanding of the governing mechanisms of laser-driven material transformations. The Project will overcome the gap between the striking experimental findings of laser-induced glass modifications and theory which is still unable to explain a number of laser-created extraordinary structures. The objectives of this multidisciplinary project are (1) to disclose the nature of formation of volume nanogratings in fused silica; (2) to find mechanisms responsible for anisotropy of direct writing of optical elements dependent on the direction of laser beam scanning; (3) to describe bubble chains formation in glasses, and (4) to develop a concept of laser-induced modification diagrams for transparent materials. Its real outcome will be in making an important step from a primitive concept of simple energy deposition on laser processing of materials toward understanding and more sophisticated description of overall phenomenon of laser-matter interaction.

Keywords: ultrashort laser pulses,glass modifications,volume nanogratings,optical elements,writing anisotropy,bubble chains,modification diagram,electron plasma,tonks-dattner modes,avalanche
Supramolecular Active Layer, Self-Assembly on Surface (SUPRAL_SAS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Switzerland
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-06-01
End date: 2013-05-31
Duration (months): 24.0
Total project cost (EUR): 178101.6
EU funding (EUR): 178101.6
Participants: 1
Project status: CLOSED

The objective of this proposal is to improve the efficiencies of organic solar cells using bio-inspired architectures. The high efficiencies of natural photosystems arise from their well-defined multichromophoric structures, which allow energy transfer processes to operate over long distances from the light-harvesting chromophores to the reaction centre. Similarly, highly organised redox pathways allow the electrons and holes generated by the photosynthetic process to travel through antiparallel pathways so suppressing charge recombination. Here, we propose the preparation of organized multichromophoric artificial photosystems to act as n/p-heterojunctions in photovoltaic devices. These assemblies will be prepared by self-organizing surface-initiated polymerization (SOSIP) of phthalocyanine and perylenediimide-based dyes, forming separate pathways for hole and electron transport. These architectures will be characterized using a number of specialist techniques to establish structure-property relationships, and ultimately optimize the systems for practical applications.

Keywords: supramolecular chemistry,macromolecular chemistry,polymer chemistry,material chemistry,photochemistry,opto-electronic components,nanoelectronics
Evaluation of metastatic and angiogenic potential of cancer stem-like cells in distinct mouse models for lung and liver metastasis. (METASTASIS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2011-11-01
End date: 2014-03-05
Duration (months): 24.0
Total project cost (EUR): 167065.6
EU funding (EUR): 167065.6
Participants: 1
Project status: CLOSED

Metastasis disease is the leading cause of cancer-related mortality with very few effective treatment options available for patients. Metastases are characterized by the presence of vascular proliferation, a subpopulation of stem-like cells and infiltration by various bone marrow derive cells (BMDCs). BMDCs have been shown to provide the premetastatic niches that promote the angiogenic process and create an environment permissive for tumor cell homing and colonization. The cancer stem cell (CSC) theory defines a subset of cancer cells with the exclusive ability to drive the growth and spread of a tumor. This research proposal is founded on the hypothesis that the CSC theory also applies to the metastasic process. The aims are to determine the relative contribution of CSCs to tumor cell homing, their ability to recruit BMDCs and induce angiogenesis. The final goals are to elucidate the mechanisms that participate in these phenomena and to develop novel therapeutic strategies to overcome metastasis initiation and progression. Briefly, using well-defined models of lung and liver metastasis, we will 1- determine if CSCs are more metastatic and angiogenic than non-CSCs; 2- identify the genes responsible for the metastatic and angiogenic capacity; 3- characterize the role of CSCs in the recruitment of BMDC; 4- examine whether cancer cells secrete factors that directly activate myeloid cells to produce tumor-promoting cytokines; 5- quantify the number of CSCs in samples from patients with lung and liver metastasis and validate their metastatic potential.

Keywords: health sciences,cancer stem-like cells,bone marrow recruited cells,metastasis,angiogenesis,cytokines.
Regulation of mesenchymal stem cells by vasculature and enhancement of their regenerative potential for the treatment of acute myocardial infarction (MESENDOT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Spain
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-04-01
End date: 2013-03-31
Duration (months): 24.0
Total project cost (EUR): 230980.0
EU funding (EUR): 230980.0
Participants: 1
Project status: CLOSED

Mesenchymal stem cells (MSCs) can contribute to the regeneration of different tissues by differentiating into a wide variety of cell types, including cardiomyocytes, adipocytes and endothelial cells among others. MSCs represent a reliable source of adult stem cells in humans. A recent report suggests that MSCs concentrate around blood vessels, although the MSC natural microenvironment (niche) is not completely understood. In this project, we aim to study the biology of Bone Marrow derived stem cells (BM-MSCs) and Adipose tissue-derived mesenchymal stem cells (ASCs) in their niche and exploit this knowledge for the treatment of myocardial infarction. We will analyze the interaction of these two types of MSCs with blood vessels, identify the molecules involved and compare which one is more effective for cardiac regeneration. Objectives: 1) Determine the effect of blood vessel-derived cells on human and mouse MSCs; 2) Define the interactions between MSCs and blood vessel-derived cells in the human and mouse MSC niche, including the identification of the molecules mediating direct cell contact and the soluble factors mediating the paracrine effect of blood vessels; 3) Determine the role of the identified factors in the MSC niche in vitro and in vivo by using recombinant proteins and neutralizing antibodies; 4) Compare the potential of BM-MSCs versus ASCs for myocardial regeneration and repair, and investigate the capacity of the identified factor s to enhance this potential. The results will contribute to the development of novel therapeutic strategies for the treatment of myocardial infarction. The project will provide specific training for the researcher in the field of human stem cells, cardiovascular research and general issues related to clinical as well as basic human research that will help the transition of her career into translational research.

Keywords: health sciences,cardiology,biological sciences