Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Using extreme magnetic field microscopy to visualize correlated electron materials (PNICTEYES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Condensed matter physics
Panel description: Structure, electronic properties, fluids, nanosciences, biological physics
Countries involved: Spain
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-03-01
End date: 2022-02-28
Duration (months): 72.0
Total project cost (EUR): 1704375.0
EU funding (EUR): 1704375.0
Participants: 1
Project status: CLOSED

Strong electronic correlations often produce intertwined phases where multiple length scales coexist. These produce spatially varying electronic properties containing unique insight on the many-body effects that determine the emergence of novel collective behavior. Addressing the problem of electron correlations requires powerful microscopes probing electronic properties down to atomic scale. A major challenge in electron correlated materials is to understand the emergence of high critical temperature (HTc) superconductivity. Fe-based superconductivity offers ultra-pure materials easily tunable through relevant phases emerging from electron correlations (antiferromagnetism, nematicity and superconductivity), providing a tremendous opportunity to unveil the microscopic pairing mechanism behind HTc superconductivity. High magnetic fields are needed to disentangle the electronic correlations, because they enable comparison between normal and superconducting phases and unveil quantum critical behavior and vortex physics. Traditional research under very high magnetic fields uses macroscopic measurements of the spatially averaged magnetic and electronic properties. The goal of PNICTEYES project is to combine very high magnetic fields with scanning tunneling microscopy (STM) to visualize spatial electronic heterogeneity in Fe-based superconductors. The microscopes developed within this project will operate up to 22 T using superconducting coils in-house and above 30 T using resistive and hybrid magnets at international high magnetic field facilities. Implementing novel spectroscopic methods, such as Landau level spectroscopy, we will disentangle the electronic correlations behind the microscopic mechanism of HTc superconductivity in Fe-based superconductors. The success of this project will provide new insights in fundamentals of HTc superconductivity and first enable ultra-high magnetic field STM opening innovative opportunities in other fields as graphene or magnetism.

Keywords: high critical temperature superconductivity,very high magnetic field,scanning tunneling microscopy,very low temperatures,strongly correlated electron materials
Identifying biomarkers of Exposure leading to Lung Cancer with Adductomics (EXACT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-06-01
End date: 2019-02-28
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Over 20% of death by cancer in the world are due to Lung Cancer (LC). Tobacco, and recently, exposure to air pollution, are considered the main causes for LC, thus specific carcinogens have been only partially identified. The complex composition of tobacco smoke and air pollution makes it difficult to identify the specific compounds responsible for the carcinogenesis process. To understand the mechanisms of LC onset, methods are needed to characterize specific toxicants that people are exposed to. We propose to develop a new method to identify exposure-specific (tobacco or air pollution) markers of LC. This new method is based on the measure of the ensemble of electrophile-carcinogens and human serum albumin adducts in human serum: the Adductome. Electrophiles present in blood are highly reactive species that have been long suspected of causing cancer because of their ability to bind DNA and proteins. Protein adducts provide more suitable markers of exposure as they have a longer life span in the blood and are present in much higher concentrations, but have been poorly investigated. In EXACT we hypothesise that protein-carcinogen electrophiles adducts can be used as markers of LC carcinogenesis and that different markers can be identified for tobacco-induced or air pollution-induced disease. Our objective is to improve the current analytical methodology for adductomics analysis and develop a new methodology for adducts structural identification in order to characterize adduct profiles in 400 samples of human serum from the EPIC cohort. Statistical analyses will be carried out to link adducts profiles to smoking status, air pollution data and methylation profiles. The elucidation of the markers structure will allow us to establish a database of candidate compounds responsible for the carcinogenicity of tobacco and air pollution. EXACT will serve as a proof of concept to develop a novel technique based on the use of the Adductome to elucidate disease causality.

Keywords: exposure,epidemiology,lung cancer,exposome,adductomics,air pollution,tobacco,carcinogens,biomarkers,analytical chemistry,mass spectrometry,omics,identification,prevention,epigenetics
Understanding blood pressure and vascular haemodynamics in implanted Left Ventricular Assist Device patients. (HIT-LVAD)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United States,United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-GF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-01
End date: 2019-08-31
Duration (months): 36.0
Total project cost (EUR): 251857.8
EU funding (EUR): 251857.8
Participants: 2
Project status: CLOSED

Background: Advanced heart failure (HF) is a growing health problem in the European Union (EU). Consequently, a growing number of HF patients now depend on state-of-the-art continuous flow Left Ventricular Assist Devices (cf-LVAD) as a bridge to transplant or as a means of destination therapy. Since the introduction and usage of cf-LVAD’s rather than traditional pulsatile LVAD’s, survival rates have significantly improved. However, an increased number of side-effects, including stroke and microvascular bleeding, have been reported. Suggested mechanisms associated with these side effects is lack of pulsatile pressure and flow throughout the system, however there are currently no data on macro/micro haemodynamics in these patients. Objectives: Columbia University’s Medical Center (CUMC) has the largest cf-LVAD programme in the world and thus will enable recruitment and assessment of the largest cohort to date of cf-LVAD patients. The aim of the project is to provide 5 work packages (WP) to understand the consequences of decreased pulsatile blood pressure (BP) and flow haemodynamics in cf-LVAD patients, compared to HF patients and age matched controls. Protocol: WP1:Measurement of BP and haemodynamics in cf-LVAD patients, using a new innovative BP device. WP2:Measurement of microvascular flow profiles in cf-LVAD patients, HF patients and healthy controls, using transcranial Doppler ultrasound and high frequency retinal Doppler ultrasound. WP3:Validation of brachial BP in cf-LVAD patients. WP4:Development of an improved LVAD device. WP5:Re-integration and Transfer of Knowledge back into the EU. Outcome: The project will require the fellow to re-integrate and transfer ALL of the newly acquired knowledge and skills from the world leading institution of CUMC back to the host institution, local community, national and EU clinical and industrial partners. This will facilitate the fellow to become a leading European authority in haemodynamics associated with LVAD patients.

Keywords: vascular haemodynamics,implantable devices,blood pressure
European Cohort Development Project (ECDP)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Estonia,Italy,Spain,Finland,Greece,Croatia,Hungary,Slovakia,Latvia,Netherlands,United Kingdom,United Kingdom,United Kingdom,Portugal,United Kingdom
Call: Design Studies (H2020-INFRADEV-2017-1, 2017)
Start date: 2018-01-01
End date: 2019-12-31
Duration (months): 24.0
Total project cost (EUR): 2048880.0
EU funding (EUR): 2048880.0
Participants: 17
Project status: CLOSED

The European Cohort Development Project (ECDP) is a Design Study which will create the specification and business case for a European Research Infrastructure that will provide, over the next 25 years, comparative longitudinal survey data on child and young adult well-being. The infrastructure developed by ECDP will subsequently coordinate the first Europe wide cohort survey, which we name EuroCohort. This is achieved through the following three objectives: i. Building support from key political policy makers with a brief which covers child well-being as well as national funding agencies tasked with infrastructural spending on science and survey data collection ii. Develop a scientifically excellent research design iii. Establish a robust operational framework that will ensure the logistic integrity of EuroCohort. The culmination of ECDP is in the creation of an infrastructural platform with a commitment from key stakeholders across Europe and from which the next stages in finalising EuroCohort can begin. There is at present no equivalent data source available to scientists to comparatively analyse the well-being of children as they grow up and therefore to develop policies to improve their well-being. As the respondents to EuroCohort grow up an increasing body of data will develop, becoming ever richer and informative, able to show the ways in which national policies have made impacts and showing where policy interventions can make significant improvements. ECDP has a tripartite focus on securing political support, operational robustness and scientific excellence. We recognise that each of these imperatives are necessary to the development of a successful research infrastructure, as scientific excellence alone is not enough. ECDP comprises a range of Work Packages that detail the specific requirements of a EuroCohort, the costs that would be involved and the policy benefits that accrue.

Keywords: child and youth well being,comparative european longitudinal cohort survey,research infrastructure,evidence based policy making,child and youth transitions to education,employment and beyond
Predicting Suicide (PS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands,United States
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-07-30
End date: 2021-07-29
Duration (months): 36.0
Total project cost (EUR): 242929.8
EU funding (EUR): 242929.8
Participants: 2
Project status: CLOSED

There is a pressing need for improvements in methods that accurately measure and predict those most likely to engage in suicide and self-harm. Traditional methods that rely solely on explicit self-reports are limited because participants can be unwilling to express thoughts or behaviours that they perceive to be socially deviant. In addition, they might not have introspective/conscious access to certain thoughts that can increase their risks of engaging in self-injurious behaviours. Similar impression management problems occur for researchers addressing prejudice and stereotyping, and consequently, implicit tasks that measure automatic biases are of immense value in clinical and social domains. This project will use the Simple Implicit Procedure (SIP) - a highly advanced implicit measure that was developed and validated by the applicant to overcome the limitations in existing implicit measures- to predict those most likely to attempt suicide. The SIP can be used to precisely specify the cognitive mechanisms that are driving an automatic bias, which will offer researchers across a host of domains crucial additional information. This additional insight can be used to assist with the development of interventions aimed at reducing problematic behaviours or thoughts. This project will also use a biopsychosocial approach to determine crucial factors that heighten the risks of suicide, addiction and prejudice. The training I will receive will secure me as the leading figure in advanced implicit measurement, with the necessary infrastructure and international collaborations developed, to establish a lab aimed at providing solutions to major societal problems. Using both front-line pragmatic methods and broad theoretical perspectives to better understand the causes of self-injurious behaviour, addiction and prejudice, I will be better placed to make recommendations to policy makers, who can then greatly improve the lives of the most vulnerable people in our society.

Keywords: implicit cognition,simple implicit procedure,suicide,self harm,addiction,prejudice and stereotyping,clinical and social interventions,online experiments,big data,automatic biases
wireless Body Area Networks for high density MYOelectric neurorehabilitation technologies (MyoBan)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Society and Enterprise panel
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-05-01
End date: 2019-04-30
Duration (months): 24.0
Total project cost (EUR): 168277.2
EU funding (EUR): 168277.2
Participants: 1
Project status: CLOSED

The next generation of rehabilitation systems will require the evaluation and restoration of the motor impairment using neural information. For this purpose, noninvasive multichannel electromiographic (EMG) technologies are the most promising tools for research and clinical neurorehabilitation applications. Unfortunately, the current systems for high-density (HD) EMG recordings require long cables that impose significant restrictions on the patients and limit free movement. Moreover, the integration of such bulky systems into current rehabilitative exoskeletons may be problematic. For these reasons, the project MyoBan aims to develop an innovative portable HD EMG system based on recent standards designed for the next generation of wireless body area networks. The proposed system will exploit the spatial and temporal characteristics of the surface EMG signals to reduce the data-rate and optimize transmission parameters (e.g. transmitting power, specific absorption rate, real-time processing, etc.). The final aim will be the production of small HD EMG sensors that can be placed on the surface of multiple muscles of the patients with minimal invasiveness and high efficiency. The project will combine expertise in several fields: telecommunication, biomedical signal processing, medical information technologies and neurorehabilitation. The MyoBan is expected to produce substantial progress in the research and clinical applications of neurorehabilitation technologies for motor restoration.

Keywords: high density,wireless,body area networks,sensors,neurorehabilitation
From Social Interaction to Abstract Concepts and Words: Towards Human-centered Technology Development (TRAINCREASE)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Italy,Poland,Denmark,United Kingdom
Call: Twinning (H2020-WIDESPREAD-2020-5, 2020)
Start date: 2021-01-01
End date: 2024-06-30
Duration (months): 42.0
Total project cost (EUR): 899638.75
EU funding (EUR): 899638.75
Participants: 4
Project status: SIGNED

This project is aimed at strengthening the interdisciplinary field of research on the emergence, understanding and use of abstract concepts and words in human interaction, and its application to human-machine collaboration. The main goal is to strengthen the research and innovation potential of the UW as part of European Research Area (ERA) as well as its reputation and visibility in the ERA and worldwide through the collaboration with University of Manchester (UMan), Sapienza University of Rome (Uniroma1) and Aarhus University. The three partners are especially well suited to collaborate towards the objectives: UMan provides expertise in computational modeling of abstract concepts and words in the context of developmental robotics. Uniroma1 provides strong theoretical background and expertise in experimental research, including neuroimaging studies. AU provides a complementary anthropological perspective and expertise in naturalistic research on the social dimension of abstraction. UW provides expertise in ecological approach to abstraction and in dynamical systems theory and methods, which has integratory potential for the field. The objectives will be achieved by a series of joint activities logically planned to increase excellence both in the field and in the UW's research and management potential: Theory Building and exchange of Complementary Methods; staff, ESRs and administratiion project-targeted exchanges, including a novel scheme for hands-on training (Microtwinning); joint publications and joint grant applications. The Twinning will result in the staff's and ESRs' increased research skills in the field, which is envisioned as one of the most crucial for the cognitive sciences and its exchanges with AI, stabilization of the improvements through structural and curriculum changes, transfer of skills to the grant-managing staff and through development of stable connection within ERA and with non-academic stakeholders as a reliable collaborator and leader.

Keywords: abstract concetps,abstract words,language development,human coordination,human robot,interaction
Low-Cost Real-Time Nanomagnetooptical Integrity Monitoring Tool and Intelligent Asset Integrity, Risk and Performance Management Software (NANO)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Portugal
Call: Engaging SMEs in security research and development (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2017-01-01
End date: 2018-12-31
Duration (months): 24.0
Total project cost (EUR): 3237589.75
EU funding (EUR): 2266312.83
Participants: 1
Project status: CLOSED

EQS aims to deliver a low-cost highly sensitive real-time remote monitoring tool and a intelligent web-based software to manage asset integrity, safety and performance, for the Oil, Gas, Chemicals and Energy markets. This new disruptive market solution, based on nanotechnology, will increase the resilience of critical energy installations and networks, allowing the reduction of human losses, avoiding energy production disruption, minimizing environmental and economic impact and material damage from natural and man-made disasters. Proximally 60% of the incidents in the EU’s hazardous industries are due to integrity failures and in 50% of these cases, ageing is a significant factor. Structural integrity monitoring can provide far greater integrity knowledge than traditional inspection methods, critically increasing safety with significant maintenance cost reduction through the early detection of problems. These tools combined with advanced societal and individual risk assessment methods significantly improve the risk management over the asset lifetime. The NANO concept is to provide a cost-efficient real-time asset management solution, capable of performing the screening of degradation, condition assessment, safety and environmental monitoring in large pipelines, process equipment, industrial plants, terminals and offshore structures. The monitoring tool will be the first combining nanotechnology with magnetostrictive generated ultrasonic Guided Waves and Fibre Bragg Gratting. Through an advanced material fabrication process, it will be possible to have a low cost monitoring solution with higher sensitivity level than any other inspection tools. The Asset Management software will bring the novelty of combining physical and human assets risk management and asset integrity monitoring data. It will be also possible to obtain 3D web visualization of the asset’s integrity, safety and performance, providing qualitative and quantitative information to improve decisions.

Keywords: chemicals,energy,real time remote monitoring,nanotechnology,magnetostrictive,guided waves,high sensitivity sensing,inspection,critical installations,structural integrity
FLying ultrA-broadband single-shot InfraRed sensor (FLAIR)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Research and Innovation actions
Partnership: Photonics (cPPP)
Countries involved: Spain,Switzerland,Switzerland,Sweden,Netherlands,Denmark,Denmark,United Kingdom,Portugal
Call: Photonics KET 2016 (H2020-ICT-2016-1, 2016)
Start date: 2016-11-01
End date: 2020-12-31
Duration (months): 50.0
Total project cost (EUR): 4277813.75
EU funding (EUR): 3072020.0
Participants: 9
Project status: CLOSED

FLAIR aims at developing an airborne, compact and cost-effective air quality sampling sensor for sensitive and selective detection of molecular fingerprints in the 2-5 μm and 8-12 μm infrared atmospheric windows. The sensor is based on an innovative supercontinuum laser that provides ultra-bright emission across the entire spectrum of interest. Such a light source in combination with a novel type of multipass cell in conjunction with specifically developed uncooled detector arrays will ensure highly sensitive detection. Broadband single-shot 2D high resolution absorption spectra capture will allow highly selective molecular detection in complex gas mixtures in the ppbv levels in real time. This high performance sensor constitutes a breakthrough in the field of trace gas spectroscopy. Moreover, in a hybrid approach, the main spectroscopic sensor will be complemented by a fine particle detector in order to obtain a complete picture of the air quality. Mounted on an adapted and optimized UAV (drone), the sensor will enable pervasive sensing on large scales outside urban environments where air quality monitoring remains challenging, e.g. along gas pipelines or around chemical plants. Also, FLAIR can guide emergency measures in case of chemical fires or leaks, wildfires or volcanic eruptions or even serve for oil and gas exploration or explosives related molecules detection, by far more cost-effectively than for missions on manned research aircraft. As such FLAIR provides a novel and ubiquitous tool addressing air quality related safety issues. The sensor prototype will be tested at TRL 4 in the lab and at TRL 5 on-board a UAV in the context of a well-defined and controlled validation test setting. The project will be carried out by 3 SMEs, 1 industrial partner and 4 RTDs, covering the full value chain (development, implementation and application) of such a sensor for air quality monitoring. Business cases for commercialization routes in a global market will be provided

Keywords: spectroscopy,air quality monitoring,airborne sensor