Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
INERATEC Modular Plants for Renewable Chemical Products (IMPOWER2X)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Germany
Call: SME instrument (H2020-EIC-SMEInst-2018-2020-3, 2020)
Start date: 2021-05-01
End date: 2023-06-30
Duration (months): 26.0
Total project cost (EUR): 3492082.5
EU funding (EUR): 2444457.75
Participants: 1
Project status: SIGNED

INERATEC (IC) sells modular chemical plants for the production of CO2-neutral fuels and materials based on greenhouse gases and renewable power. IC`s disruptive innovation is a micro-structured reactor technology, which can be integrated into containers, allowing a numbering-up that makes the exploration of local and world-scale renewable feedstock sources economically feasible. The Fischer-Tropsch reactor is simultaneously producing e-Diesel and e-kerosene – two renewable products, which, after separation and final conditioning, can help customers in road transport and aviation to significantly reduce their CO2 footprint. IC has implemented 10 demonstration plants so far, reaching TRL 7. With IMPOWER2X TRL 9 is reachable. To become even more successful, IC must transform its technology from demonstration applications to industrial application, consequently reducing the costs to provide the technology. To achieve that, existing plant concepts will be modularized and standardized, a serial production of the modules as well as the reactors built up and plants implemented at industrial scale and at customers’ sites. Additionally, the public and political acceptance for renewable fuels must be sharpened. IC will be able to either sell its plants or to provide long-term off-take agreements to customers in the field of e Diesel and e-kerosene, finally allowing to reduce the CO2 footprint of the individual customers by nearly 100%. Geographical sweet spots as well as promising customers worldwide will mainly be targeted. IMPOWER2X is in alignment with IC’s strategy of strengthening its position as market leader for synthetic, renewable fuel. With IC’s solution, customers and countries will be able to reach their climate targets and positively contribute to the environmental targets. This way the proposal serves the goals of the Green Deal by supporting the EU´s climate mitigation ambitions by helping to come to a clean and sustainable mobility and industry.

Keywords: e fuels,renewable energies,synthetic fuels,modular production
Smart Planning, Operation and Control for Energy Internet (SPOCEI)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Norway
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-01-19
End date: 2024-01-18
Duration (months): 24.0
Total project cost (EUR): 214158.72
EU funding (EUR): 214158.72
Participants: 1
Project status: SIGNED

The planning, operation and control is of importance to the Energy Internet (EI). With large numbers of energy routers (ERs) integrated into EI, the EI system becomes more complex and variable. This state of affairs renders it is necessary to develop new architecture, modelling, optimization and control methods, in order to achieve intelligent, distributed, reliable, exible and cooperative system operation for EI. To this end, the researcher proposes the following three unique researcher actions in this project, including: 1) controllable structure planning for multi-ER-based EI under different environments (before and after fault) from the concept of controllability view; 2) distributed and adaptive cooperated control strategies based on deep policy gradient algorithm to enable each microgrid adaptively to respond to the system model switching without the need of exact system dynamics; 3) multiple timescale power trading model and distributed optimization algorithm to achieve both optimal energy generation/consumption and optimal energy flow allocation among ER with faster convergence rate in different timescales. Our project has the potential to produce new technological transformations and overcome multiple critical bottlenecks in the development of the current power grid from “smart grid” to “EI”. Through many inter-sectoral training, project management and communication activities, the research will gain comprehensive experience and skillsets, which is conducive to his future career prospects. This project effectively combines the researcher’s expertise in distributed control as well as optimization theories and the participating organizations’ expertise in energy informatics and energy management, planning of power grid and artificial intelligence, resulting in ensured two-way knowledge transfer. Moreover, our project fits well with the EU energy development strategy, which will contribute to European energy innovation and applications.

Keywords: energy management,artificial intelligence,energy internet,energy router,distributed control and optimization
Neuromodulation of Sensory Processing (NeuroSens)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-07-31
Duration (months): 27.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

Neuromodulation, such as that associated with paying attention, changes the way our brains interpret our sensory experiences. Understanding the neuromodulation of neural circuitry that integrates and processes incoming sensory input to generate a meaningful output remains a fundamental question in neuroscience. While the neuromodulator acetylcholine is shown to enhance sensory responses, the cellular mechanisms by which it mediates these effects are still poorly understood. Recent evidence suggests that the local subthreshold dendritic potentials, dendritic spikes, which are important in synaptic input integration, also play a key role in encoding feature selectivity, the ability of neurons in sensory cortices to be tuned to specific features of a stimulus. Interestingly, ion channels, such as potassium channels that regulate dendritic spikes are also shown to be modulated by cholinergic inputs. Here, I propose that acetylcholine modulates sensory processing via modulation of dendritic spikes. I will use a combination of state-of-the-art in vivo imaging, electrophysiology, pharmacology and optogenetics to test the novel hypothesis that acetylcholine modulates sensory processing by regulating dendritic spikes and thereby feature selectivity in mouse somatosensory cortex. The project will provide new cellular insights into a long-standing question on the mechanisms of neuromodulation of sensory processing. It builds on my expertise in neuroanatomy and physiology and will give me the opportunity to master advanced in vivo techniques in a host environment that is well known for their in vivo expertise and research into neuromodulation. Given my strong background in neurodevelopmental disorders, the project will push the knowledge frontier on neuronal processing and will provide a framework for research into basic mechanisms of sensory perception and their alterations in neurological disorders.

Keywords: neuromodulation,sensory processing,in vivo,dendritic integration,somatosensory cortex,two photon microscopy,optogenetics,synapse
Hippocampus Extracellular Space Simulator Project (HESSP) (HESSP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Spain,United States
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2024-08-30
Duration (months): 36.0
Total project cost (EUR): 245732.16
EU funding (EUR): 245732.16
Participants: 2
Project status: SIGNED

Understanding the human brain is one of the biggest scientific challenges of the 21st century, and this endeavor has led the European Union to launch the Human Brain Project (HBP) as a FET flagship project. However, even a flagship project such as the HBP cannot study all aspects of the human brain. One aspect that is not covered by the HBP is the extracellular space (ES). The ES of the brain is important in the field of neuropharmacology because it is key to the successful delivery of drugs to the neurons. Also, the importance of the metabolite clearance activity of the ES has led to proposing that a dysfunction of this process plays a role in neurodegenerative diseases. However, to the best of the eligible researcher’s knowledge, no initiative exists to create an ES simulation software that improves the research. To address this lack of simulation software, this proposal presents the Hippocampus Extracellular Space Simulator Project (HESSP). The HESSP’s goal is to develop a simulation software for how substances released by neurons and chemical substances that pass the blood-brain barrier diffuse through the ES. Specifically, the HESSP will create a software that simulates the diffusion process in the ES of the mouse’s hippocampus. The HESSP is an interdisciplinary project that involves computer science, neuroscience and pharmacology, and it addresses the challenge of developing a software architecture to simulate a diffusion process highly complex due to its number of elements formed. The hippocampus was chosen because it is a well-known structure, the results can be tested, and it is the earliest brain structure affected in Alzheimer’s disease (AD). The HESSP will open a frontier line of research at the host university in collaboration with leading scientists in ES and neurodegenerative diseases. Additionally, the eligible researcher will acquire frontier knowledge in the simulation of complex biophysical processes and in neuroscience.
Universal PlugPlay OEE Data Capture Equipment to improve the efficiency of industrial processes (Smooth Reader)

Framework: Horizon 2020 — Industrial Leadership
Programme: Nanotechnologies, Advanced Materials, Advanced Manufacturing and Processing, and Biotechnology
Theme: Nanotechnologies
Action type: SME instrument
Countries involved: Spain
Call: Accelerating the uptake of nanotechnologies, advanced materials or advanced manufacturing and processing technologies by SMEs (H2020-SMEINST-1-2015, 2015)
Start date: 2015-09-01
End date: 2016-02-29
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The production lines of industrial companies are very heterogeneous, with machines from various brands, models, generations and technologies. Due to this heterogeneity, the bespoke solutions for data capture are very expensive and are difficult to implement. For this reason, the penetration of data capture solutions in companies is very low. Sistemas OEE de Productividad Industrial, S.L.L. has developed some innovative universal equipment for automated Real-Time Data Capture on production lines, called Smooth Readers. They are a true breakthrough due to its universal system of connection and for its ability to achieve a connection with the machines in a very brief time, practically making it a Plug and Play. It is a range of standard products that are easily configurable in situ by the client (DIY), or remotely via the web, which cover the requirements for data capture/collection of almost the totality of the machines on the market. The main innovations of the Smooth Reader system include the following: - Plug and Play. Installation in production line in less than one hour. - Breakthrough technology at cost level. - Universal product, connectable to any production process. - Great connectivity that allows the capturing of numerous parameters. - Include a portable kit to perform pilot tests. - Modular and scalable system. The innovation is based on a self-developed algorithm, the result of three years of research, that is used to program the Smooth Reader, and which allows it to communicate with any type of machine. Sistemas OEE makes the data capture systems for the improvement of productivity accessible for European SMEs, so these SMEs can incorporate progressively advanced production technologies. The objective of this phase 1 is to complete a feasibility study to find out the workability and profitability of the business venture. If the result of the feasibility study is positive, we will apply to phase 2 in order to implement our international expansion.

Keywords: production lines,industrial companies,data capture,productivity,universal,configurable,connectivity,pilot,test,production losses,hardware,advanced control systems
A novel platform for user-friendly spectroscopy at very low temperatures and under strong magnetic fields (U-SPEC)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC Proof of Concept Grant (ERC-2015-PoC, 2015)
Start date: 2016-11-01
End date: 2018-04-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

One of the most appealing opportunities in the field of Materials Science is the development of multifunctionality. Thus, it is becoming crucial to characterize materials upon acting on more than one physical property at a time. Magnetoelectric, photomagnetic or photoelectric phenomena are some of the bases of future technologies. Most of the equipment available nowadays for materials characterization includes options to study materials (magnetic, electric, etc.) under light irradiation. However, the effect of temperature or magnetic fields upon light-matter interactions is not commonly studied due to the intrinsic difficulties of such a set-up. We have designed a novel insertion probe (U-SPEC), which allows collecting transmitted light through a sample in a cryogenic confined environment. Our probe can be adjusted and used with any cryogenic equipment (using nitrogen or helium as carrier, or under high vacuum). We have validated its correct function in the 1.7 - 400 K range and under magnetic fields up to 7 T. In these conditions, U-SPEC allows studying UV-Vis and IR spectroscopy, but also dichroic phenomena, since it is able to maintain light polarization. Such features are unparalleled in the market place of scientific instrumentation, and confer to our invention high commercial value. Our aim is to develop a product concept, protect the intellectual property, and design a business model to bring our technology to market. Beyond the commercial interest, U-SPEC will also have a strong scientific impact in the long term. The availability to gather spectroscopic experimental data in such a controlled environment, routinely, represents a breakthrough in materials science. Nowadays, such studies are exclusively accessible to few specialized groups around the world. U-SPEC will bring extraordinary capabilities to standard labs and research institutions.

Keywords: spectroscopy,cryogenics,materials science
WISER – the energy saving and burglar proof window that breathes for enhanced indoor comfort (WISER)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Action type: SME instrument
Countries involved: Poland
Call: Stimulating the innovation potential of SMEs for a low carbon energy system (H2020-SMEINST-1-2015, 2015)
Start date: 2015-12-01
End date: 2016-05-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

BGTEC is a Polish SME, active since 1996 in the production of customised windows and fenestration products for high-end clients; our current niche market consists of new constructions and deep retrofitting projects, in particular nearly zero energy single-family houses, villas and passive houses. As a result of our continuous product development efforts to fulfil market demand, in 2012 we have conceived an innovative idea for a reversible window technology, the WISER window. Windows operated through a rotation across mid axis are state of the art, however none of them allows users to rotate the window sash 180° and lock it in the new position. WISER reversible window technology is enabled by innovative hydraulic gaskets and burglar-proof electro-magnetic locking mechanisms fully integrated in the structure of the frame, operated via a simple to use control system which can be integrated to a central building automation infrastructure or central security system. WISER is the only window that can reduce the thermal radiation from the outside during summer season, and reduce the thermal dispersion from the interior in the winter, thanks to the double positioning of the low-E glass. Enhanced ventilation is permitted through an innovative use of the active gaskets, permitting air flow while keeping the window locked. WISER window can be easily adapted to different climates and seasons along the year as well as material combinations and building types. WISER allow easy, cheaper and safer cleaning of glasses on both sides. WISER product family is aimed to change the way people interacts with windows: its unique design satisfies in a single product the needs for energy efficiency, indoor climate, security as well as easier and safer cleaning. It represents therefore an incredible business opportunity for us to move from a niche onto a multi-million market with a much larger international presence, in line with the ambition of the projects to get funded under the SME Inst.

Keywords: energy efficiency,indoor quality environment,burglar proof window
Uncovering the mechanisms of osteoarthritis in human knee applying spatial transcriptomics (SpatialArth)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2022-11-03
End date: 2026-11-03
Duration (months): 24.0
Total project cost (EUR): 174806.4
EU funding (EUR): 174806.4
Participants: 1
Project status: CLOSED

Osteoarthritis (OA) is the most prevalent chronic musculoskeletal disorder causing pain, morbidity and disability, giving rise to enormous healthcare expenditures and loss of work. The exact triggers and pathogenesis of OA are still poorly understood. Currently, there are no measures to slow down the progression of OA. Bulk tissue-based multi-omics and small-scale single cell RNA-seq studies focussing on chondrocytes and synoviocytes have identified novel cell clusters, supporting the hypothesis that OA is a disease of the whole joint. However, one of the key relevant tissues (bone) have not yet been studied. In addition, approaches to date have employed lengthy live cell extraction approaches that affect the transcriptome pattern. Finally, the spatial dimension of molecular changes in the osteochondral unit has not been studied to date. This work will fill this fundamental gap in our understanding of the molecular aetiopathogenesis and progression of OA by employing a novel cutting-edge technique, spatial transcriptomics (ST). ST acts like a high-throughput molecular microscope to allow visualisation and quantitative analysis of the transcriptome with spatial resolution in individual tissue sections, affording near-single cell resolution. SpatialArth will generate new knowledge on the molecular profile of the osteochondral unit and will identify with spatial resolution which cells are involved in the pathogenesis of OA. I will combine ST sequencing and protein expression data from cartilage and bone tissues from OA patients (matched tissues from intact and degraded regions of tibial plateau) and tissues derived from non-OA knee joints. Additionally, I will develop my computational genomics skillset, aiming to help fill the need for a much-needed next generation of interdisciplinary researchers. SpatialArth addresses several mandatory European Union calls - finding strategies supporting healthy and active aging and decreasing the economic burden on healthcare.

Keywords: spatial transcriptomics,knee osteoarthritis,cartilage,subchondral bone,multi omics
Digital Innovation Hubs boosting European Microelectronics Industry (DIATOMIC)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: Innovation actions
Countries involved: Germany,Spain,Serbia,Greece,Belgium,Luxembourg,Portugal,United Kingdom,Portugal
Call: Smart Anything Everywhere Initiative (H2020-ICT-2016-2, 2016)
Start date: 2017-09-01
End date: 2020-08-31
Duration (months): 36.0
Total project cost (EUR): 7087506.25
EU funding (EUR): 6267643.75
Participants: 10
Project status: CLOSED

DIATOMIC aims to establish a sustainable ecosystem to facilitate AME/SSI-based innovation in the health, agrifood and manufacturing sectors, all of which are under-digitized and of prime importance for society and the economy. DIATOMIC ecosystem draws from the advanced technological excellence of the DIATOMIC consortium to execute three sector-specific cross-border Application Experiments to help technology adopters, end-users and smart solution developers realise tangible benefits of digitization. In-house excellence in dissemination is leveraged to ignite further ideation of digital products, processes and business models from non-tech SMEs and midcaps; thus promoting interest in experimentation with AME and SSI. At the heart of the ecosystem, three interconnected sector-specific Digital Innovation Hubs (DIH) pulsate to accelerate digitization in-beat with sector-specific needs, and to enable delivery of AME/SSI based applications to a critical mass of customers. DIHs first assist non-tech companies to couple with counterparts across the EU with complementary technological competencies. Then, acting as a one-stop-shop, they offer the teams (i) strong technological support to accelerate design, development, prototyping and manufacturing and (ii) business support to develop solutions with a robust product/market fit. Two open calls are organised to attract and select the best of the best consortia, consisting of tech adopters, tech providers and Competence Centers. Application Experiments will be funded to generate AME/SSI-based products, processes and business models with strong market potential. DIATOMIC delivers the structure and three instances of sector-specific DIHs, +75 Competence Center, +20 application experiments, along with a validated ecosystem sustainability plan. DIATOMIC consortium is a fusion between: technological research centers (IPA, IPN and BIOS), CCs (INTRA, LIB and SYN), innovation consulting (INO), SMEs community (F6S) and investors (FASTT).

Keywords: digital innovation hub,competence centers,entrepreneurs,advanced micro electronics,and smart system integration,cross border experiments