Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Bioethanol from paper fibres separated from solid waste, MSW (FIBREETOH)

Framework: FP7 — Cooperation
Programme: Energy
Destination: Renewable fuel production
Action type: Collaborative project
Countries involved: Finland,Sweden,Germany
Call:  (FP7-ENERGY-2008-TREN-1, 2008)
Start date: 2010-01-01
End date: 2013-12-31
Duration (months): 48.0
Total project cost (EUR): 16260640.0
EU funding (EUR): 8649972.0
Participants: 9
Project status: CLOSED

The EC Directives set ambitious targets for mandatory 10 % biofuels share in road transport. 2nd generation biofuels will give significant benefits as ethanol blends in gasoline and synthetic biodiesel products. The innovative focus in the FibreEtOH project is to demonstrate for the first time globally in a commercial scale, a cost efficient paper fibre based ethanol production with high, &gt; 70 % overall energy efficiency with high &gt; 50 % green house gas reduction. 2nd generation ethanol production technology has been developed using mainly corn stover, straw or saw dust as raw material. So far reliable and cost efficient hydrolysis technology has been the bottleneck for large scale commercial success. By using paper fibres separated from commercial and municipal solid waste or de-inking sludge at paper mills, the hydrolysis process will be significantly easier as no pretreatment and special fractionation process is needed. It is estimated that such raw material is available in quantities for more than one million t/a ethanol production capacity. The EtOH production cost will be highly attractive due to the low price of the waste based raw material and the distillation steam compared to typical straw and wood EtOH production plants. The proposed demonstration plan with 20 000 m3/a ethanol production capacity will be build using 250 000 t/a waste from Helsinki metropolitan area in Finland. Biogas, district heat and electricity will be produced from the by-products. The site and environmental permits have already been granted. The ethanol will be used in Finland in dedicated E5 – E85 blends optimising the ethanol fuels to cold climate conditions and tail pipe emissions reduction. The FibreEtOH-proposal will demonstrate innovations in a novel 2G EtOH production chain using optimized and cost-effective enzymatic hydrolysis process taking advantage of the adjacent enzyme production and the whole production concept with high overall process integration.

Keywords: fibre,ethanol,biofuel,waste,muncipal solid waste
Molecular genetic regulation of eye field development (EYEDEVELOPMENT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2009-06-01
End date: 2013-05-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

Anophthalmia and microphthalmia, birth defects that are important causes of childhood blindness, often arise as a result of abnormal development of eye progenitors in the eye field during early embryogenesis. The molecular genetic mechanisms that underlie eye progenitor development in the eye field are not well understood. This proposal aims to identify cellular, molecular and genetic mechanisms of eye progenitor development during the eye field stage using zebrafish as a model organism. We will focus on regulation of eye field development by the transcription factor Six3, whose loss of function has been shown to cause anophthalmia or microphthalmia in humans and several genetic model organisms including zebrafish. We will use a combination of in vivo studies with genetic and molecular approaches toward two specific objectives: first, we will identify cellular mechanisms underlying loss of eye progenitors during eye field stage in Six3-deficient zebrafish embryos, which exhibit anophthalmia or microphthalmia. This will be achieved by following eye progenitors in live Six3-deficient embryos and determining their fates. Subsequent analyses will address the molecular mechanisms that lead to these fates. The second specific objective will identify protein-coding genes and miRNAs that are important for eye field development, with focus on downstream targets of Six3. This will be achieved using a transgenic approach to isolate eye field cells from wild-type and Six3-deficient embryos and identify protein-coding genes and miRNAs that are specifically expressed in the eye field and whose expression is affected by the loss of Six3 function. Together, these studies will lead to better understanding of the genetic network that underlies early eye development. Such knowledge is necessary for improving the ability to provide genetic counseling and may also help in prevention of severe eye malformation.

Keywords: molecular genetics,developmental biology,zebrafish,eye field,six3,anophthalmia,microphthalmia
Polygeneration through pyrolysis: Simultaneous production of fuel oil, process steam, electricity and organic acids. (EMPYRO)

Framework: FP7 — Cooperation
Programme: Energy
Destination: Energy efficiency and savings
Action type: Collaborative project
Countries involved: Netherlands,Netherlands,Germany,Denmark
Call:  (FP7-ENERGY-2008-TREN-1, 2008)
Start date: 2009-12-01
End date: 2015-09-30
Duration (months): 70.0
Total project cost (EUR): 9314611.2
EU funding (EUR): 4949947.0
Participants: 8
Project status: CLOSED

A 25MWth poly-generation demo plant will be build at the site of AkzoNobel in Hengelo (NL). It will produce fuel oil, process steam, electricity and organic acids through pyrolysis of wood. These products will be used on-site. An overall energy efficiency of 78% will be achieved. AkzoNobel will replace natural gas used for both energy generation and chemicals production. Pyrolysis involves rapid heating of biomass in absence of air. Resulting vapours are condensed, leading to three products; char, pyrolysis oil and gas. The char and gas are combusted to yield process steam, used for drying and power production. From the aqueous pyrolysis oil fraction organic acids will be extracted. The technology to be deployed is developed by BTG, a leader in the European pyrolysis market. BTG built its first bench-scale pyrolysis plant in the mid 1990’s. Since then the technology has been scaled-up to 10MWth. In this project the capacity will be scaled-up further by a factor 2.5. The technology has not been demonstrated on this scale in Europe. Five of the seven partners are based in Twente (Netherlands). The others are based in Germany and Denmark. Four partners are SME’s. Work covered includes: WP1 Biomass collection and pre-treatment, WP2 Pyrolysis plant engineering and construction, WP3 Pyrolysis plant operation and optimisation, WP4 Pyrolysis oil application, WP5 Organic acid recovery, WP6 Economic evaluation, WP7: Dissemination and training, WP8 Project management. For large-scale dissemination an educational centre and a Pyrolysis Platform will be established. European experts will be involved in awareness raising and competence building. Pyrolysis oil can be utilised in existing boilers, requiring little extra investment. Prospects for uptake in the chemical and other industries are excellent. Preparations for the demo plant started late 2007. A basic design has been completed. Financing for the investment is being arranged. Steps to acquire permits have been taken.

Keywords: biomass,pyrolysis,polygeneration
Open Gromov-Witten theory, real symplectic geometry and mirror symmetry (REALSYMPOPENMIRROR)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2009-11-01
End date: 2013-10-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

A great deal of research in symplectic geometry has revolved around Gromov-Witten invariants, a mathematical model of the physics of closed strings. Recent research in string-theory indicates that there should be an open-string analog of Gromov-Witten invariants, despite certain mathematical complications. In my thesis, I introduced a working definition of open Gromov-Witten invariants for real symplectic manifolds. I intend to study the properties of these new open Gromov-Witten invariants, and investigate how to extend the definition further. In my thesis, I established a connection between open Gromov-Witten theory and real enumerative geometry as developed in the recent seminal work of J. Y. Welschinger. Progress in open Gromov-Witten theory should shed light on a host of problems in real enumerative geometry, especially the connection with traditional complex enumerative geometry. The study of open Gromov-Witten theory in the context of real geometry has revealed a deep and little studied relationship between real geometry and mirror symmetry. Mirror symmetry is a striking collection of conjectures originating from string-theory that predict a comprehensive duality between symplectic geometry and complex geometry. Intuition and knowledge from symplectic geometry and complex geometry can thus be combined to solve otherwise intractable problems. In recent collaborative work with R. Pandharipande and string-theorist J.Walcher, we have verified an important example of mirror symmetry in the real open Gromov-Witten setting. I believe my research, which bridges a gap between geometry and string theory, as well as my ongoing collaboration with physicists will help build a culture of interdisciplinary interaction. Moreover, I plan to convey the knowledge I have acquired in ongoing collaborative work with leading researchers in the United States to students and researchers with whom I have already developed ties in Europe.

Keywords: open gromov-witten theory,symplectic geometry,real enumerative geometry,mirror symmetry,floer theory
Control and Application of Field Induced Polymer Patterns (POLYPATT)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Ireland
Call:  (FP7-PEOPLE-ERG-2008, 2008)
Start date: 2009-04-01
End date: 2011-03-31
Duration (months): 24.0
Total project cost (EUR): 30000.0
EU funding (EUR): 30000.0
Participants: 1
Project status: CLOSED

Strong electric field gradients can produce forces that overcome the surface tension in a thin liquid polymer film to induce instabilities at the film surface. It is possible in this way to create structure in polymer films on a nanometre length scale. Understanding how the resultant patterns form has significant potential for improving nanodevice fabrication techniques but may also lead directly to the discovery of novel nanodevices. As part of the PATTERNs RTN, over 35 months the applicant has worked with some of the leading researchers in the thin film polymer instabilities field, and has been fully trained in the relevant experimental and theoretical methods. He has developed a new theoretical model that describes a polymer-air-polymer system under electric field and he has explored this system, not only theoretically but experimentally. The applicant has validated his theoretical model, and explored comprehensively the polymer type, thickness and viscosity parameter space of this system to provide new insights into the nucleation and spinodal processes responsible for the observed pattern formation. The experimental results are however from static measurements, and so detail of the dynamic instability formation process remains obscured. He proposes therefore to study the real-time formation of the polymer instabilities using a newly acquired optical 3-D topographic instrument modified for this purpose. In addition, the ambition of fabricating nanodevices based on these polymer instabilities requires an increased level of experimental control, and the coupling of these instabilities with nanoparticle inclusion for self-organisation into nanodevices (such as photonic crystals) is at the forefront of current research and still not well understood. He proposes therefore to develop new methods for controlling the experimental polymer instability system, and to use this control to allow fabrication and characterization of nanoparticle self-organised devices.

Keywords: soft matter and polymer physics
Nonlinear Analysis in Mathematical Models: Heat Damage, Stability of Nonlinear Waves and Spectral-Scattering Problems (NLAMATHMODELS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Slovakia
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2009-10-21
End date: 2013-10-20
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The major obstacle in mathematical modeling in science that is also responsible for the variety of different phenomena appearing is its nonlinear nature. Richard Kollar's field of research is nonlinear analysis that includes mathematical modeling and the study of existence and stability of coherent structures as nonlinear waves, vortices, and defects, appearing in models ranging from nonlinear optics, or condensed matter physics to chemical processes in human brain. The value of these problems lies not only in their far-reaching consequences for applications, but also in the interesting mathematics underlying them. The goal of the three projects in this proposal is to gain insight by studying interesting particular applied problems, and apply it to build and simplify the general theory. The goal of the first project is to study heat damage of cells, particularly during burn injuries and hyperthermic cancer treatments. Based on his current research, Kollar proposes to extend his mathematical model to include important effects as increased vascular permeability or three-dimensional nonhomogeneous environment. In the second project Kollar, in collaboration with R. Pego, B. Deconinck and N. Kutz, studies stability of certain nonlinear waves. Besides other investigations it requires an extension of the Evans function technique for detection of unstable eigenvalues to three-dimensional and non-local problems. The third project, in collaboration with P. Miller, proposes to use Krein signature and Pontryagin spaces in the study of inverse scattering-spectral problems. The idea discussed in the proposal is to use Krein signature to restrict the position of spectra for potentials satisfying a single-lobe condition introduced by Klaus and Shaw. A prominent common feature of this proposal is a very novel approach to classical problems and the unification of different theories.

Keywords: nonlinear waves,differential equations,biomathematics,spectral problems,integrable systems,burn injuries
Role of secretases in myelination (SECRETASES & MYELIN)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2010-05-01
End date: 2014-04-30
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 2
Project status: CLOSED

The development of glial cells, oligodendrocytes (OL) in CNS and Schwann cells (SC) in PNS, critically depends on axonal contact. Gliogenesis and the phenotype of myelinating glia are regulated by axons. Glial cells promote neuronal survival, regulate the organization of myelinated axons and promote axonal differentiation and myelin sheath production. We recently showed that type III NRG1, a member of the Neuregulin1 (NRG1) family of proteins, is an essential instructive signal for myelination in PNS and directs the ensheathment fate of the axons. We also showed that type III NRG1 promotes CNS myelination and that myelination in CNS and PNS are differentially regulated. Previous studies indicate that membrane bound NRG1 are cleaved by secretases. Upon cleavage in the extracellular region type I and type II NRG1 are released from the neuronal membrane, while type III NRG1 remains tethered on the axonal surface and acts as a juxtacrine signal. The extracellular cleavage is likely to be mediated by the alpha-secretase TACE and by the beta-secretase BACE1. Our studies suggest that type III NRG1 intracellular cleavage is SC dependent and mediated by the gamma-secretase complex. In these studies we will determine the role of these cleavage events in myelination. We will analyze if lentiviruses expressing non-cleavable type III NRG1 can rescue in vitro myelination of type III NRG1 -/- neurons and if non-cleavable type I NRG1 proteins can substitute for type III NRG1. We will also investigate the nature of the molecules regulating NRG1 extracellular cleavage. We will focus on TACE and we will analyze in vitro and in vivo myelination in the absence of TACE. Finally, we will examine if type III NRG1 intracellular cleavage promotes neuronal survival. These studies will provide major insights into the role of type III NRG1 in myelination and will be relevant to develop new therapeutic strategies to promote axonal survival and remyelination.

Keywords: neurobiology,degenerative diseases,chronic diseases,cell biology,laboratory animal science
Short and Long-term Stock Market Returns from Innovation Outsourcing: A Comparative Analysis of Domestic versus Offshore High-Tech Markets (INNOVATION-SOURCING)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Türkiye
Call:  (FP7-PEOPLE-IRG-2008, 2008)
Start date: 2010-02-15
End date: 2014-02-14
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The main objective of this proposal is to capitalize on the scholarly experience the applicant researcher has acquired in the United States and contribute to the advancement of the state-of-the-art research conducted in Koc University, in Turkey as well as in Europe. The project “Short and Long-term Stock Market Returns from Innovation Outsourcing: A Comparative Analysis of Domestic versus Offshore High-Tech Markets (INNOVATION-SOURCING)” aims to provide an understanding on the returns and risks of a firm’s decision to outsource its innovation development. Specifically, this research addresses the following questions: (1) what are the effects of innovation outsourcing on short versus long-term stock market performance and are firms better off outsourcing innovation domestically or offshoring; (2) what sources of dependence and uncertainty impact short versus long-term stock market performance in the domestic versus offshore outsourcing contexts; and (3) overall, what is the optimal innovation outsourcing spending as reflected in the market stock returns? The implementation of this research project requires the training and the cooperation of doctoral students, and hence, may contribute to reversing of the effects of the European brain drain to third countries. The subject matter in this research project may also allow the development of enduring collaborations with the scientific and industrial milieu of Europe and the USA. Given the timeliness and significance of the topic, this project not only has the potential to contribute to the researcher’s long term professional integration, but also to the scientific excellence and competitiveness of Europe as a whole.

Keywords: european marketing,market analysis,industrial relations,innovation management,technology management
South-East European TSO Challenges (SEETSOC)

Framework: FP7 — Cooperation
Programme: Energy
Destination: Smart energy networks
Action type: Collaborative project
Countries involved: United Kingdom,Greece,Bulgaria,Romania,Serbia,North Macedonia,Italy
Call:  (FP7-ENERGY-2008-TREN-1, 2008)
Start date: 2010-01-01
End date: 2012-12-31
Duration (months): 36.0
Total project cost (EUR): 3452800.0
EU funding (EUR): 2292300.0
Participants: 16
Project status: CLOSED

The proposed project addresses the needs of South-East European TSOs in their effort towards harmonization and integration of the region with the rest of the European power network. Diagnostics, modeling and monitoring generate huge amounts of data that create the need for efficient storage and analysis of the collected information for better decision making and execution; under this respect the use of a common computational platform is highly recommendable and will be a focus of the proposed project. The project objectives are: • Assist in harmonizing regulatory and commercial frameworks in South East Europe to facilitate cross-border trading of both power and grid services, ensuring that they will accommodate a wide range of operating situations; • Development of systems and tools that will enable TSOs and other players in the energy field to utilize innovative service arrangements to improve their efficiency and enhance their services to customers; • Develop and implement methods and techniques for capacity calculation and allocation. • Establish corrective procedures to ensure security of power transmission and grid connections. • Ensuring the successful interfacing of new and old methods and tools for the representation and modeling of power networks. The consortium has a strong representation (50%) of TSOs that take part from the initial to the final stages of the project to ensure appropriate input of information, proper use of methods and techniques and practicality of outcomes. Academic institutions with expertise and research in the field are heavily involved through their electrical engineering departments. Furthermore international cooperation is ensured with the participation of two TSOs and two academic institutions from EU neighboring countries. The results/products of the project that are in electronic form (software, data) will be publicly available (open source) to researchers and businesses for further development and implementation.

Keywords: tso challenges south east europe integration monitoring modeling