Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Prostate MR Medical Imaging Biomarker Platform (QUIBIM qp-Prostate)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: Coordination and support actions
Countries involved: Spain
Call: European SME innovation Associate - pilot (H2020-INNOSUP-2020-02, 2020)
Start date: 2020-10-01
End date: 2021-09-30
Duration (months): 12.0
Total project cost (EUR): 121428.57
EU funding (EUR): 85000.0
Participants: 1
Project status: CLOSED

Our company, QUIBIM S.L., is a high-tech SME specialized in machine learning and image processing technologies applied to the creation of imaging biomarkers from medical images. The core of our business is QUIBIM Precision®: https://precision.quibim.com/: a world-class medical imaging quantitative analysis platform used by dozens of hospitals and medical research institutions. As of writing, the platform is able to analyse lung and brain images. After analysing the market, the technology, our own capabilities and the rate of incidence of diseases we have decided to put the focus for the period 2020-2021 on updating the Platform with a novel module addressed to the analysis of prostate MR images. This new module will take the name of qp-Prostate® The module will include several analysis plugins, which focuses on the analysis modules of Diffusion - ADC and Perfusion - Pharmacokinetics, specifically for prostate cases. Finally, before start marketing our solution, as a medical device, we will also need the corresponding Regulatory Certifications, scientific and regulatory reviews to evaluate the safety and effectiveness of the new medical software device. New horizons for QUIBIM S.L.: Since the QUIBIM was born, we have put tremendous efforts in the development of our own R&D and resulting technologies in automatic data analysis, machine learning and algorithms to allow a better performance and accuracy in medical images explorations, identifying quickly patterns and details not obvious to the human eye. The company wishes to market qp-Prostate®, an image processing software package to be used by trained professionals, including radiologists specialized in prostate imaging, urologists, oncologists and MR technicians. qp-Prostate® will be the first imaging biomarker analysis platform specifically for prostate MR, allowing QUIBIM to lead a novel (and unexploited) market of this sort of imaging biomarkers.

Keywords: prostate,medical imaging,imaging biomarkers,artificial intelligence
CIPHRA (CIPHRA)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Sweden
Call: SME instrument (H2020-SMEInst-2018-2020-1, 2019)
Start date: 2020-01-01
End date: 2020-06-30
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The story of data breaches across industries with national, regional, and often global impact is a never-ending one. The exposure of huge amounts of personal information and identities continues to be a major problem without a solution in sight (see sample on the left of recent breaches to tech giants). At the nexus of the world of cyber security and cyber-crime is the paramount issue of password and encryption key storage – the security measures in place to prevent hacking, and the capabilities of the illegal hackers to hack into storage sites and decipher encrypted messages.Authentico has invented CIPHRA which is a hardware dependent cryptographic processor that ensures that passwords and encryption keys are essentially impossible to steal even if a database is hacked into. CIPHRA protects the cryptographic infrastructure by securely processing passwords, and generating unclonable encryption keys from authentication requests using a technology called PUF (physically unclonable functions). Authentico´s solution stands to be a major alternative to traditional key storage methods. The keys are always present in the device, by generating the key on request. Information, such as password hashes, can be inputted, but never read out or extracted. Even weak passwords cannot be broken because the generated outputs are useless for an attacker and the database of encrypted and hashed passwords is useless without the key. This is a far better solution than current approaches because the company’s secret keys are never stored anywhere, at any time, making it extremely difficult for any malicious insider or outside hacker to ever gain access to them.

Keywords: physically unclonable functions,encryption
Probing New Physics at the Large Hadron Collider: the Effective Field Theory Pathway (EFT4NP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: United Kingdom
Call: ERC STARTING GRANTS (ERC-2020-STG, 2020)
Start date: 2022-01-01
End date: 2026-12-31
Duration (months): 60.0
Total project cost (EUR): 1407726.0
EU funding (EUR): 1407726.0
Participants: 1
Project status: SIGNED

The Large Hadron Collider (LHC) is hunting for signs of New Physics (NP) in the vast amount of data collected by its experiments. If new states are heavier than the collider energy reach, their presence can be revealed by modifications of the interactions of the known particles. The Standard Model Effective Field Theory (SMEFT) parametrises such deviations from the SM, extending the sensitivity to scales beyond those directly probed at colliders. Determining the parameters of the EFT will shed light on the nature of NP and will provide hints to the most important questions in particle physics, such as the shape of the Higgs potential, its relation to electroweak baryogenesis and the amount of CP-violation and its connection to the matter-anti-matter asymmetry. A dedicated campaign of measurements and their SMEFT interpretation is a major goal of the LHC and requires coordination between experimentalists and theorists. I aim at making essential beyond the state-of-the-art theoretical contributions to the LHC SMEFT programme by: 1) Providing the first fully generic next-to-leading order QCD and electroweak Monte Carlo implementation of SMEFT operators, to allow theorists and experimentalists to perform realistic simulations. 2) Combining accurate SMEFT predictions with LHC data to constrain the operators through a novel robust global determination. The findings, particularly if different from the SM expectations, will point to the scale and nature of NP. 3) Exploring new challenging proposals, such as i) the impact of operator running and mixing and ii) the optimisation of ways of extracting the Higgs self-coupling and probing CP-violation at the LHC, two topics with profound implications for our theoretical understanding of particle physics. The proposal plays to a key strength of my research expertise and my research record uniquely positions me to successfully lead this ambitious project, which is vital to exploit the full LHC potential.

Keywords: large hadron collider,phenomenology,standard model effective field theory,new physics,precision calculations
Dissecting the crosstalk between metabolism and transcriptional regulation in pluripotent stem cells. (MetEpiStem)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Cellular, Developmental and Regenerative Biology
Panel description: Structure and function of the cell, cell-cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Italy
Call: ERC Starting Grant (ERC-2016-STG, 2016)
Start date: 2017-10-01
End date: 2024-03-31
Duration (months): 78.0
Total project cost (EUR): 1498232.0
EU funding (EUR): 1498232.0
Participants: 1
Project status: SIGNED

Pluripotent Stem cells (PSCs) can give rise to all differentiated cells of the body and the germ line, which makes them conceptually fascinating and a valuable tool for regenerative medicine. Mouse PSCs are devoid of any developmental restriction partly thanks to their “open” chromatin, characterised by remarkably low levels of repressive epigenetic modifications. Metabolism is a key feature that can be adjusted to meet the cell’s needs, and that has the potential to feedback on transcription and epigenetics. How metabolism is regulated in PSCs and whether this is important for their biology remains largely unknown. We recently found a new molecular mechanism by which energy production is coupled to pluripotency. Here we propose to deepen our understanding of how metabolism, epigenetics and transcription are reciprocally regulated for the self-renewal and differentiation of PSCs. To gain insights into how metabolism is dynamically regulated in concert with the transcriptome and epigenome, we will also use somatic cell reprogramming into PSCs, a process in which both the metabolic and epigenetic profiles must be reset to match those of PSCs. Moreover, taking advantage of the recent generation of novel human PSCs sharing most of the transcriptional and epigenetic features found in naïve mouse PSCs, we will explore how metabolic regulatory mechanisms key for the generation and maintenance of pluripotency are conserved throughout evolution. Altogether, large-scale transcriptional, epigenetic and metabolic profiling of PSCs, combined with cutting edge technologies for their generation, expansion and genetic manipulation, will give us the unprecedented opportunity to build a comprehensive computational model of the metabolic network in PSCs, and to study how gene transcription and metabolism regulate each other.
OECD Study on the Incidence and Impact of Tax Support for Research and Innovation (TAX4INNO)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: Coordination and support actions
Countries involved: France
Call: Europe (H2020-Adhoc-2014-20, 2014)
Start date: 2016-01-01
End date: 2019-12-31
Duration (months): 48.0
Total project cost (EUR): 1014595.0
EU funding (EUR): 600000.0
Participants: 1
Project status: CLOSED

This project is part of efforts to monitor and assess research and innovation policies in Europe and beyond. New indicators and empirical policy analysis can contribute to the coordination and increased focus of individual country policy efforts to obtain the desired impact on growth, jobs and prosperity through research and innovation policies. In recognising the role of innovation in tackling 21st century challenges, this project implements the goals of the Horizon 2020 Work Programme “Europe in a Changing World: inclusive, innovative and reflective societies” by contributing new research tools and evidence on the role of public support measures as an instrument for improved innovation and socio-economic outcomes in society. Building on OECD’s unique expertise and access to a number of networks of official national experts, this project aims to: (1) Provide new evidence on the incidence and design of R&I tax incentives, building internationally comparable evidence on the size and nature of incentives provided by governments to support R&D and innovation through their tax systems; (2) Deliver new evidence on the impact of R&I tax incentives, deepening our understanding of the impacts of R&D tax incentives on business innovation and economic performance, through within- and cross-country econometric micro-data analysis; and (3) Fostering knowledge sharing on the incidence, design and analysis of impact of R&D tax incentives.

Keywords: randd,randi,innovation,tax support,impact,tax incentives
Structural Engineering of 2D Atomic Planes towards Task-Specific, Freestanding Superstructures through Combined Physical-Chemical Pathway (CHEPHYTSSU)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-07-25
End date: 2018-07-24
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

The research on 2D nanomaterials has boomed since the discovery of graphene by professors Geim and Novoselov in 2004. After a decade of steady development, the available library of 2D crystals is highly rich including graphene derivatives, hexagonal boron nitride, many chalcogenides and various oxides. However, the technological advances and urgent environmental and sustainable energy issues such as CO2 capture and separation, energy storage and conversion (photovoltatic system, supercapacitor etc) call for advanced materials with not only properties of individual layers but also new functionalities. Particularly, researches on superstructures with unique properties such as amphiphilicity still remain blank. Physically, it is now possible to create such hybrid superstructures by placing different 2D crystals on top of each other in a designed sequence; while engineering the 2D units through a chemical way endows a high flexibility in surface chemistry tailoring and increase the mechanical stability due to the strongly bonded interface. Taking these into consideration, here we propose a combined chemical-physical pathway to engineer task-specific, mechanically freestanding superstructures based on 2D atomic planes in a simple and scalable manner. Three new material concepts are proposed including amphiphilic superstructure (hydrophilic outer layer and hydrophobic inner layer), gas selective superstructure (CO2-phililc outer layer and gas shape selective inner layer) and flexible superstructure with outer layer functionalized with metal oxide nanoparticles confined in ordered mesopores and inner conductive graphene. The obtained superstructures with these structural features will be oriented environmental and sustainable energy issues such as CO2 capture and separation, water purification and flexible electrode. Finally, structure-performance relationship will be unraveled fundamentally.

Keywords: graphene,2d materials,2d superstructures,co2 capture,co2 separation,energy storage,energy conversion
Utility Business Model Transformation through human-centric behavioural interventions and ICT tools for Energy Efficiency (UtilitEE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Innovation actions
Countries involved: Spain,Germany,Spain,Spain,Ireland,Cyprus,Switzerland,Greece,Poland,Finland,France
Call: Behavioural change toward energy efficiency through ICT (H2020-EE-2017-RIA-IA, 2017)
Start date: 2017-11-01
End date: 2021-04-30
Duration (months): 42.0
Total project cost (EUR): 2787200.0
EU funding (EUR): 1999977.51
Participants: 12
Project status: CLOSED

Utilities are facing political pressure to reduce the energy end use by their customers and GHG emissions. Consumers, on the other hand, are empowered by the proliferation of IT interfaces and multiplication of channels. Their expectations for everything-anytime-anywhere interaction are redefining the nature of (energy) services. The advent of smart building technologies for energy efficiency reveal a mega-trend on the evolution of consumer choices and highlight the need for addressing their requirements for user-friendly, meaningful and actionable communication. Faced with these realities, business as usual is no longer an option for energy utilities. They must seek new sources of revenues by introducing bundled building energy management service packages including energy efficiency, smart controls and automation. The UtilitEE project will provide a customer-oriented Behavioural Change Framework (Energy-as-a-Service delivery approach via an open ICT ecosystem integrated into the building with off-the-shelf sensors). It focuses on discovering, quantifying and revealing energy-hungry activities and conveys meaningful feedback to engage users into a continuous process of learning and improvement. UtilitEE will leverage well-known behavioural models/ theories and standardized operational rating/ certification methods. It will also incorporate human-centric intelligent control features that use occupant comfort profiles and supportively control HVAC and lights so as to minimize energy waste, while always keeping occupants comfortable and preserving a healthy indoor environment. The framework will be validated in real-life conditions by a large population of residential and commercial consumers and aims to reduce energy use by ~30%. Validation activities will also explore future business models and go-to-market strategies for utilities. A holistic roadmap and business plan for the exploitation and replication of project results will be delivered.

Keywords: behavioural change,energy behaviour profiling,human centric intelligent guidance,control and automation,energy as a service,new business models,open innovation,cleanweb
SECurity And privacy protectioN in Internet of Things devices (SECANT)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Theme: Improve cyber security
Action type: Innovation actions
Countries involved: Germany,Spain,Spain,Ireland,Spain,Cyprus,Sweden,Romania,Romania,Greece,Greece,Greece,Greece,France,Netherlands,United Kingdom
Call: Intelligent security and privacy management (H2020-SU-DS-2020, 2020)
Start date: 2021-09-01
End date: 2024-08-31
Duration (months): 36.0
Total project cost (EUR): 6700185.87
EU funding (EUR): 5202226.38
Participants: 21
Project status: SIGNED

The SECANT platform will enhance the capabilities of organisations’ stakeholders, implementing (a) collaborative threat intelligence collection, analysis and sharing; (b) innovative risk analysis specifically designed for interconnected nodes of an industrial ecosystem; (c) cutting-edge trust and accountability mechanisms for data protection and (d) security awareness training for more informed security choices. The proposed solution’s effectiveness and versatility will be validated in four realistic pilot use case scenarios applied in the healthcare ecosystem. Ultimately, SECANT will contribute decisively towards improving the readiness and resilience of the organisations against the crippling modern cyber-threats, increasing the privacy, data protection and accountability across the entire interconnected ICT ecosystem, and reducing the costs for security training in the European market.

Keywords: distributed ledger,trust and accountability,security awareness,security training
An infrastructure for experimental research for sustainable pig production (PIGWEB)

Framework: Horizon 2020 — Excellent Science
Programme: Research Infrastructures
Theme: Research infrastructures
Destination: Integrating activities and infrastructures
Action type: Research and Innovation actions
Countries involved: Germany,Germany,Germany,Spain,Hungary,Sweden,Switzerland,Belgium,Hungary,Finland,France,Netherlands,Netherlands,Denmark
Call: Integrating Activities for Starting Communities (H2020-INFRAIA-2020-1, 2020)
Start date: 2021-03-01
End date: 2026-02-28
Duration (months): 60.0
Total project cost (EUR): 5733787.21
EU funding (EUR): 4999992.57
Participants: 18
Project status: SIGNED

Research infrastructures (RI) play a key role in identifying levers that can be used to attain the goals of the Green Deal and the “Farm to Fork” strategy, to which PIGWEB can contribute by a “From Pig to Pork” approach. The aims of PIGWEB are to strengthen the pig research community by providing and facilitating access to RI, reinforce a culture of cooperation between the research community and industrial and societal stakeholders, and improve and integrate the services provided by the RI. This will contribute to develop innovative and ethical solutions for sustainable pig production systems. To attain these aims, the project will: - Ensure easy and transparent access to experimental pig RI and associated laboratories. - Create a community of pig RI by mapping installations beyond partners of the project and identifying future research needs in pig production sector. - Harmonise protocols, best practices, and promote the use of standards to ensure high level of expertise and ethics. - Organise the collection, management, and accessibility of data generated by the project. - Ensure dissemination, exploitation, and technology transfer of results generated by the project. - Provide graduate and post-graduate training opportunities to young researchers to ensure the succession of a new generation of highly-trained experts in the fields of pig production. - Develop non- or minimally invasive methods for digestion studies and blood sampling to replace current procedures requiring surgery and invasive sampling, isolation, fixation and/or spatial restrictions of pigs. - Develop novel methods, tools and technologies that provide indicators of welfare, behaviour, and body composition. - Develop a research toolbox (based data obtained through non- or minimally invasive measurements and model algorithms) to phenotype pigs for traits relevant for sustainable pig production.

Keywords: infrastructure,sustainable pig production,health,welfare,ethics,quality food products,low environmental impact,improved service,dialogue with society,open science,community building