Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Technologies and methods for improved resilience and sustainable preservation of underwater and coastal cultural heritage to cope with climate change, natural hazards and environmental pollution (THETIDA)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Greece,Italy,Netherlands,Portugal,Norway,Cyprus,France,Switzerland
Call: Effects of climate change and natural hazards on cultural heritage and remediation (HORIZON-CL2-2022-HERITAGE-01, 2022)
Start date: 2023-05-01
End date: 2026-10-31
Duration (months): 42.0
Total project cost (EUR): 3999287.5
EU funding (EUR): 3999287.0
Participants: 17
Project status: SIGNED

The THETIDA project approaches safeguarding and protecting Europe’s coastal and underwater cultural heritage from the effects of climate change and natural hazards in a holistic manner that includes risk management, protection and preparedness, as complementary strategies to prevent damages to CH sites, identify and ward off additional threats and promote policy tools for climate neutrality and economic resilience in coastal areas. THETIDA project achieves this goal through the development of a preventive conservation strategy that includes monitoring, risk preparedness and management, for underwater and coastal CH (U&C-CH) sites, identify and ward off additional threats and promote adaptation, reconstruction and other post-disruption strategies to restore normal conditions to the historic area, as well as long-term strategic approaches to adapt to CC and to wield policy tools for economic resilience. In this project, an interdisciplinary team of researchers, experts and practitioners will develop, test and validate an integrated multiple heritage risk assessment and protection system with evidence-based monitoring frameworks, innovative tools and instruments and through participatory processes (Citizens’ Science and Living Labs). The project implementation actions will link the social innovations with cutting-edge technologies (ICT and IoT harmonised tools).
Dependencies and volatility spillovers among carbon, energy, and stock markets in the EU (ECS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-12-15
End date: 2025-03-14
Duration (months): 27.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 1
Project status: CLOSED

The EU is now on course to accomplish its 2020 climate and energy targets, and has finalized the regulatory framework required to attain its 2030 and 2050 emissions reduction goals. The EU Emission Trading System (ETS) was established in 2005 with the objective of limiting global warming and maintaining a balance between economic development and environmental protection. Financial and energy markets are the main driving forces of the prices of the carbon future market. It's also conceivable that shocks to driving forces have an impact on EUA pricing. As far now, price formation in the ETS, the consequences of structural changes on market linkages, and co-movement between the markets across different trading phases of EU ETS remain widely unexplored. Hence, the goal of this study is to explore the dynamic causal relationship, price spillovers, and dependencies among carbon-energy-stock markets during 2005-2021. To achieve this objective, it is essential to investigate the stationarity and structural breaks of variables by ADF, PP, KPSS, and ZA tests. To design a network causal relationship, directed acyclic graphs (DAG) as an alternative data-based approach will be used to modeling and analyzing contemporaneous causality patterns. Then, a Time-Varying Parameter VAR model (TVP-VAR) will be applied to discuss the volatility spillover effects. For multi-dimensional analysis, Vine Copulas, including R-Vine, C-Vine, and D-Vine models will be applied. The EUA daily future price from, stock market indices (DAX, FTSE100, CAC40, FTSE MIB, IBEX35, Euro stoxx50, respectively), and energy prices for Brent oil and gas will be utilized for a sample period (2005-2021). Novel outcomes from the study could be explored for three phases of the EU ETS. The study determines whether there are any relationships or volatility spillover effects among the markets. Dependency analysis will quantify the correlations and reveal the impact of energy and financial markets on the carbon market.

Keywords: natural resources and environmental economics,econometrics,financial markets,statistical methods,macroeconomics,asset prices and international finance
Lattice determination of the muon's anomalous magnetic moment (MUON)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-10-01
End date: 2028-09-30
Duration (months): 60.0
Total project cost (EUR): 2085625.0
EU funding (EUR): 2085625.0
Participants: 1
Project status: SIGNED

On 4/7/2021 the Fermilab announced the result of a two decade long investigation to determine the magnetic moment of the muon. By tradition, data-driven theoretical methods have been used for 50 years to calculate this magnetic moment. But, interestingly, in the last 20 years growing discrepancies were noted between theoretical and experimental findings. In the literature, the result obtained by using the data-driven method is called the “consensus value" - and it is 4.2 sigma away from the combined experimental result. This 4.2-sigma discrepancy was interpreted by many physicists as a sign for new physics with a new and unknown force - and hundreds of papers appeared in the last few months to explain the 4.2-sigma tension by some form of new physics. For theoreticians this is an extremely exciting situation because even better experimental results are expected in the next 1 to 5 years, which might further increase the tension between experiment and theory. I propose a completely different and much more fundamental theoretical approach: lattice Quantum Chromodynamics (QCD). Within this new approach I can reach better accuracies than those of the traditional approach. Furthermore, my innovative approach uses far less experimental inputs, reducing the effects of uncertainties associated with input. The objective of the present application is to show unambiguously that either (a) there is no new force, that the experimental results are actually in agreement with the Standard Model of particle physics or (b) confirm the existence of new physics with a high confidence level. To that end a very large-scale lattice Quantum Chromodynamics approach will be applied using supercomputers to yield the muon's magnetic moment with the unprecedented precision of 10(up-10) level of accuracy. The success of this project will open a new window for high precision lattice Quantum Chromodynamics and put a final word on the two decade old mystery around the muon's magnetic moment.

Keywords: elementary particle,lepton,quantum chromodynamics,quantum electrodynamics,ab initio calculations,lattice field theory,supercomputer calculations
Advancing Fertility and Reproduction thrOugh Dedicated and Innovative Technological Applications (AFRODITA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain,Belgium,Ireland,Italy,Denmark,Netherlands,United States,France
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2024-03-01
End date: 2028-02-29
Duration (months): 48.0
Total project cost (EUR): 4232439.77
EU funding (EUR): 4006864.8
Participants: 17
Project status: SIGNED

The development of assisted reproductive technologies (ART) has provided an alternative for people with difficulties conceiving naturally, and over 9 million babies have been born through ART since 1978. Moreover, the use of ART has increased dramatically (5.3-fold) during the last two decades and this trend will continue. While ART have undoubtedly made a positive impact on the lives of couples and individuals dealing with infertility, numerous studies reported potentially negative ART-derived effects on the health of offspring. The mechanisms involved and their consequences are poorly understood and there are critical unanswered questions, including whether the manipulations and the artificial environments in which gametes and embryos are cultured, or the increased paternal and maternal age at the time when the treatments are applied entail ART-derived health risks. Thus, there is a growing need to advance research on ART consequences and propose holistic solutions, as well as to develop innovative training programmes to prepare new researchers to deal with such concerns. The AFRODITA (Advancing Fertility and Reproduction thrOugh Dedicated and Innovative Technological Applications) consortium takes up this challenge and aims to implement jointly an innovative international, multi-sectorial, and multidisciplinary research and training programme (Joint Doctorate) by bringing together key scientific staff from the academia (5 European universities and 3 excellent research centres), the largest hospital in Denmark and the corporate world (8 enterprises) with a history of fruitful collaboration, that will guarantee excellent training and effective supervision for AFRODITA’s 15 doctoral candidates to enhance their career opportunities for different professional paths.

Keywords: reproductive biology,in vitro fertilization,assisted reproductive technologies,epigenetic impact
Cosmic nOn-Linearities: Impact of BaRyons on cosmological Inference with modern galaxy surveys (COLIBRI)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Universe Sciences
Panel description: Astro -physics/ -chemistry/ -biology; solar system; planetary systems; stellar, galactic and extragalactic astronomy; cosmology; space sciences; astronomical instrumentation and data
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2025-12-01
End date: 2030-11-30
Duration (months): 60.0
Total project cost (EUR): 1499806.0
EU funding (EUR): 1499806.0
Participants: 1
Project status: SIGNED

Cosmology is entering a new era with revolutionary surveys aimed notably at mapping dark matter and constraining the nature of dark energy. However, the observables are always related to "visible" matter (baryons) which is a biased tracer of dark matter. Baryons do not passively follow the assembly of dark matter structures, but they also feedback on the distribution of dark matter, and therefore impact significatively the estimators probing cosmology. If these effects are not precisely taken into account, they induce biases and could potentially engender apparent tensions, some of which are already observed, between the various cosmological surveys and probes. The COLIBRI project proposes to robustly keep under control the effect of baryons on the joint analysis of galaxy lensing and clustering data through i) new theoretical frameworks to capture efficiently the cosmological information content on mildly non-linear scales affected by baryons and ii) novel hydrodynamical simulations accurately resolving baryonic physics inside unprecedentedly large volumes, enabled by innovative simulation techniques and the evolution of computing resources in Europe in the exascale era. These simulations and theoretical schemes will then allow for a robust characterisation of baryons on cosmological scales, in order to interpret current and future large galaxy surveys with enough precision and accuracy. This effort is crucial to make the most out of the rich datasets that will be observed, with in particular the upcoming Euclid’s data releases.

Keywords: theory,simulations,weak lensing,galaxy clustering
Deciphering cellular and viral determinants of lytic HSV-1 infection, latency and reactivation (DecipherHSV)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Immunity, Infection and I mmunotherapy
Panel description: The immune system , related disorders  and their mechanisms , biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases , innovative imm unological tools and approaches , including  therapies
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-05-01
End date: 2028-04-30
Duration (months): 72.0
Total project cost (EUR): 1998008.75
EU funding (EUR): 1998008.75
Participants: 2
Project status: SIGNED

Herpes simplex virus 1 (HSV-1) is an important human pathogen which infects the majority of the world`s population and inflicts a substantial burden of disease. Over the past 10 years, systems biology approaches, to which my lab has provided seminal contributions, have substantially broadened our understanding of the complex interaction of this common pathogen with its human host. However, the underlying molecular mechanisms remain poorly understood and their importance for virus latency and reactivation remain elusive. Furthermore, currently available technology lacks the temporospatial resolution to decipher the cellular and viral determinants that govern the virus life cycle. The main goal of DecipherHSV is to close these knowledge and technology gaps and decipher novel mechanisms and their functional interplay by which HSV-1 manipulates its host cells throughout the virus life cycle. Accordingly, the three primary objectives of DecipherHSV are to: (i) decipher the full complement of viral elements that govern productive infection; (ii) decipher how and why HSV-1 manipulates pervasive transcription within the host and viral genome; and (iii) decipher the cellular and viral determinants of HSV-1 latency and reactivation. Alongside, I will develop new computational approaches and integrative analysis tools, and employ artificial intelligence to exploit the wealth of information that is provided by the novel single cell RNA sequencing approaches, which I will pioneer (Heterogeneity-seq and Perturb-scSLAM-seq). Thereby, I will deliver new leads for novel therapeutic approaches targeting HSV-1 latency and reactivation. This will provide a paradigm for the study of other herpesviruses and their complex host-pathogen interactions.

Keywords: herpes simplex virus 1 latency reactivation viral elements pervasive transcription systems biology single cell rna seq
Quantum-based Randomness Processing Units (RPUs) for High-Performance Computation and Data Security (RPU)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Challenges
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator Challenge: Emerging semiconductor or quantum technology components (HORIZON-EIC-2023-ACCELERATOR-01, 2023)
Start date: 2024-03-01
End date: 2026-02-28
Duration (months): 24.0
Total project cost (EUR): 3908437.5
EU funding (EUR): 2499999.0
Participants: 1
Project status: SIGNED

Quside has developed the Randomness Processing Unit (RPU) that is an innovative hardware accelerator designed for world-class performance, optimization, and efficiency in stochastic High Performance Computing (HPC) and Post-Quantum (PQ) cryptography. The purpose of the RPU is to accelerate and optimize randomized workloads, which are used in countless sectors (secure data transfer, finance, physics/chemistry simulations etc.). All the commercial processing/acceleration hardware (CPUs, GPUs, TPUs, etc.) generate pseudo-random numbers (PRNGs), which are sequences of digits with certain “random” statistical properties. In fact, PRNG are completely predictable and therefore are inefficient/ineffective for randomized workloads. In short, the existing processing hardware are not optimized for random numbers and operations. As a result, customers run highly inefficient processes that impact the quality of their results and increases their costs (both OPEX and CAPEX). Our technology is brand-new (the TRL 7 prototype of the RPU was presented in December 2022) and protected by 14 patent families (filed or granted). The RPU is based on the high-speed, high-quality Quantum Random Number Generators (QNRG) chips manufactured by Quside. Ours is one of the few companies worldwide working on this technology. Quside is a spin-off of the Institute of Photonics Sciences in Barcelona, and our solutions have been used in the experiments awarded with the 2022 Nobel Prize for Physics. According to our financial forecasts, Quside will generate over 170 M€ in turnover and 40 M€ in net profit in the period 2024-2028, mostly from sales of RPUs to customers in the public and private sectors. Note that this is a direct resubmission to the pitch phase, as recommended by the EIC jury.

Keywords: photonic integrated circuits,quantum random number generator,quantum technologies
The first comprehensive Atlas of the Milky Way (mw-atlas)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Synergy grants
Action type: ERC actions
Countries involved: Germany,Greece
Call: ERC SYNERGY GRANTS (ERC-2024-SyG, 2024)
Start date: 2025-05-01
End date: 2031-04-30
Duration (months): 72.0
Total project cost (EUR): 9957560.0
EU funding (EUR): 9957560.0
Participants: 3
Project status: SIGNED

The Milky Way is the cosmic environment in which the solar system, the Earth, and life as we know it came into being. It is also the veil through which we peer into the extra-galactic universe. Its dust obscures our view of the formation of the cosmos. Its magnetic fields distort the observations of nature's most powerful particle accelerators. Its structure and metabolism determine the great diversity of observed star and planetary systems, including our own. Due to a lack of distance information, currently most information about the structure of the Milky Way is two-dimensional, while three-dimensional information is needed. For a breakthrough in Galactic cartography and the science it enables, we will create the first comprehensive three-dimensional atlas of all the physical components of the Milky Way. Our atlas will be self-consistent between component maps, quantify their remaining uncertainties, and be the most detailed to date. Thanks to the dramatic progress in observations at all wavelengths and in algorithmic methods based on information field theory in recent years, now is the right time to do this. Our team's combined expertise in galactic astrophysics, algorithms, observations, Milky Way surveys, and information field theory with its application to galactic tomography puts us in a unique position to generate the first comprehensive Milky Way Atlas. We will apply this atlas to a number of pressing questions in cosmology, cosmic ray, and interstellar medium research and transfer the used tomography technologies into other areas, like medical imaging, Earth monitoring, and industrial data analysis.

Keywords: cosmic cartography,tomography,inter disciplinary science,medical imaging,earth monitoring,information theory,information field theory,machine learning
To Care Or To Kill: When The Needs Of The Many Outweigh The Needs Of The Few. (CareKill)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 214934.4
EU funding (EUR): 214934.4
Participants: 1
Project status: CLOSED

As epitomized by epidemics and pandemics throughout human history, including the ongoing SARS CoV-2 pandemic, social life carries risks of substantial and rapid spread of infectious diseases. Termites living in pathogen-rich environments have evolved remarkably robust social immunity mitigation strategies that effectively prevent diseases from spreading within colonies. Individual termites carefully balance whether to care for a sick nestmate and save the colony worker resources, or kill the sick nestmate to remove the risk of an infection spreading. The behavioural and immunological factors driving this dichotomy remain obscure. The CareKill action will close major gaps in our understanding the role of pathogen dose and infection stage in governing the switch from care to kill, what genes are involved in decision-making (immune pathways, neural networks, genes involved in stress), and how behavioural and immune memory impact care-kill decision making during subsequent encounters with sick nestmates. The action will capitalise on my extensive background in behavioural ecology and social immunity in termites, and integrate state-of-the-art pathogen load quantification and global gene expression analyses on actively caretaking or killing focal termites to establish if social immune memory is key to effective long-term reduction of disease risks. In doing so, this work explores novel concepts and hypotheses to close important gaps in our understanding of social immunity. CareKill will benefit from synergies of ongoing chemical ecology research in the focal termite species by my host, Michael Poulsen (University of Copenhagen), who will provide training in combining molecular techniques and termite ecology. CareKill will provide fundamental novel insights into the adaptive value of mitigation strategies that are essential to curb the spread of diseases and that allow for long-lived animal societies to sustain in the face of pathogenic threats.

Keywords: social immunity,care kill dynamics,ecological immunology,social insects