Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Silicon Cycle in the Mediterranean and Black Seas: An Isotopic Approach (SiCyMBSIA) (SiCyMBSIA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-03-01
End date: 2027-02-28
Duration (months): 24.0
Total project cost (EUR): 195914.88
EU funding (EUR): 195914.88
Participants: 1
Project status: SIGNED

The SiCyMBSIA (Silicon Cycle in the Mediterranean and Black Seas: An isotopic approach) project will be carried out by Dr. Diksha Sharma, an experienced researcher at the Centre National de la Recherche Scientifique (CNRS) in France under the supervision of Prof. Damien Cardinal. This project aims to unravel the intricate biogeochemical silicon (Si) cycling in the Mediterranean Sea (MS) and the Black Sea (BS). These two distinct marine environments offer unique opportunities for scientific exploration. The MS, with its unique oceanic characteristics, diverse ecosystems, and trophic regimes, provides an excellent opportunity for climate change research. Diatoms, an important phytoplankton group, play a crucial role in primary production and carbon export in this region. However, our understanding of their Si sources and limitations remains incomplete. By employing stable silicon isotopes (δ30Si) to analyze dissolved silicic acid and biogenic silica in the deep biogenic silica maxima and deep chlorophyll-a maxima layers, this project will quantify the role of diatoms and Si as nutrients and investigate processes governing dissolved silicic acid concentrations and biogenic silica dissolution in the intermediate and deeper layers of the MS. Along with this, understanding the seasonal pattern of exported biogenic silica from sediment traps will also be a novel aspect of this project. In contrast, the BS, characterized by its anoxic conditions and complex stratification, presents a unique challenge. This project will delve into the Si uptake by diatoms, sub-surface remineralization, and biogenic silica release through δ30Si analyses, shedding light on nutrient-driven diatom growth and biogenic silica production through hypoxic, anoxic, and H2S rich deep environments of the BS. Ultimately, this project promises to make a significant contribution to the international GEOTRACES programme and enhance our comprehension of Si cycling in these critical marine ecosystems.

Keywords: isotope geochemistry,oceanography,silicon,diatoms,silica cycle,mediterranean sea,black sea
Ultrafast topological spectroscopy using structured light assisted by artificial intelligence (SMART-TOPOSPEC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain,Portugal,Sweden
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2025-POC, 2025)
Start date: 2026-01-01
End date: 2027-06-30
Duration (months): 18.0
Total project cost (EUR): 166071.43
EU funding (EUR): 150000.0
Participants: 3
Project status: SIGNED

In the era of quantum materials, material properties can be precisely tailored at the smallest (nanometer) and fastest (femtosecond to attosecond) scales ever controlled by humankind. Among them, atomically thin quantum materials stand out due to their remarkable conductivity and optical transparency, making them highly attractive for semiconductor and photonic industries. SMART-TOPOSPEC, integrating a team between University of Salamanca, SME Sphere Ultrafast Photonics and Lund University, aims to develop a novel all-optical metrology technique to spatially-resolve the electronic response of quantum materials. This is achieved through topological harmonic spectroscopy, an innovative approach that exploits structured ultrafast light pulses to extract spatially-resolved information about laser-matter interactions. The use of ultrafast structured light, which requires advanced diagnosis tools and manipulation techniques, opens up new avenues for characterization and quality checking of quantum materials. By innovating the use of artificial intelligence (AI) in ultrafast science, our approach will solve the inverse problem to unequivocally identify quantum material properties that can not be resolved with standard techniques. Integrating AI into advanced pulse characterization techniques will facilitate the acceleration of retrieval algorithms, paving the way for real-time, high-precision diagnostics. The project will culminate in a prototype that integrates AI-assisted topological harmonic spectroscopy with advanced laser pulse diagnostics. This method will provide a rapid, robust, cost-effective, and tabletop solution for the semiconductor industry, enabling quality control and defect detection at nanometer scales. Building on previous patents and ERC research results, SMART-TOPOSPEC translates cutting-edge science into industrial applications to impact the laser technology and semiconductor markets.
The next-gen federated cybersecurity platform for sustainable data-first architecture (Tenzir)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Tenzir is a Hamburg-based cybersecurity startup founded in 2017. Our mission at Tenzir is to make security data easy. We are fundamentally changing the way that cybersecurity operations infrastructure is built and operated. Our vision is to give security teams control over their own data and to free them from vendor lock-in through a fabric of powerful and efficient security data pipelines. Tenzir is a platform that service providers can build MDR and other value add services on top of. As an open platform, i.e. with open-source software and standardized protocols at the core, Tenzir proves attractive to service providers and enterprises that are looking for a scalable, multi-tenant security foundation that can process massive amounts of security data. Tenzir decomposes monolithic SIEM functionality and allows for flexible re-composition in a federated deployment model. This removes the burden of complexity from the users of hybrid cloud environments and security analytics. With our solution we can offload SIEM and cut consumption-based costs up to 80% without deteriorating the level or cyber protection. Furthermore, our customers take back full control over their data and create a sustainable security architecture without any vendor lock-in.

Keywords: security analytics,federated detection,streaming,data science,data engineering,csma,cyber security,cybersecurity,threat intelligence,edge security,cyber security mesh architecture
Lighting the way with Process Analytics - Revolutionizing Cell and Gene Therapy Manufacturing with the OC-400 CGAnalyzer (PRoCGeT)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Switzerland
Call: EIC Accelerator 2025 - Short application (HORIZON-EIC-2025-ACCELERATOR-01, 2025)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

We are on the cusp of a medical revolution with the rise of cell and gene therapy (CGT). CGT is groundbreaking in its potential to treat diseases currently considered untreatable, giving hope to millions of patients. However, CGT also poses significant challenges in terms of manufacturing, slowing down its wider uptake. Producing CGT safely, efficiently, and reproducibly is complex and costly. onCyt will change the game in the industry by providing a key-enabling technology that addresses these major manufacturing challenges. We developed a novel breakthrough analytical tool, the OC-400 CGAnalyzer. This analyzer can, with the push of a button, automatically measure key quality attributes of the product, at regular intervals, all along the production process. Why is the onCyt solution key to the manufacturing issues? Today, parameters paramount for the quality and yield of the product are only measured sporadically, because analysis methods are slow and require expert personnel which companies struggle to recruit. The OC-400 CGAnalyzer provides this data rapidly, fully automated, and throughout production. Operators can thus optimize the process in real-time as well as intervene to save valuable batches in case parameters indicate problems. The OC-400 CGAnalyzer, when used during production development, will also be crucial to allow companies to transition to scalable production. This will reduce the time to market for novel drugs and lower production costs, making drugs more affordable. We will drive the medical revolution by establishing ourselves as the process analytical partner in CGT. For this, we need to act fast to finalize our technical development, e.g. to complete certifications and prepare production capabilities for the scale-up we aim for. Although we have traction from industry, it will be very challenging to enter this market without certifications and pilot projects. The funding from the EIC Accelerator will help us bridge this gap.

Keywords: process analytical technology,cell and gene therapy,automation
Enzyme Immobilization for Enhanced Transdermal Penetration of Bioactive Compounds for Treating Skin Diseases (ENHANCE-SKIN)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Greece
Call: ERA Fellowships (HORIZON-WIDERA-2023-TALENTS-02, 2023)
Start date: 2024-10-01
End date: 2026-09-30
Duration (months): 24.0
Total project cost (EUR): 169326.72
EU funding (EUR): 169326.72
Participants: 1
Project status: SIGNED

The use of natural bioactive compounds (NBCs) in dermatological treatment is a promising healthcare frontier, however their effectiveness is hindered by limitations in skin penetration. Enhancing their delivery to target skin layers or specific disease sites remains a significant challenge. Encapsulation of NBCs within nanodispersions (NDs) and their embedding in a biopolymer hydrogel matrix has demonstrated promising outcomes in terms of improving the delivery of NBCs through the skin. However, there's still a need for more significant enhancement in penetration, while the reasons behind this effect remain uncertain. This project aims to overcome these challenges through the immobilization of enzymes, like hyaluronidase, that breaks down hyaluronic acid (major skin component) within the biopolymer hydrogel matrix. By prioritizing enzyme immobilization as a catalyst for enhanced penetration, this project pushes the boundaries beyond traditional encapsulation methods. This project plans to extract bioactive compounds from natural sources and investigate effective biocompatible encapsulation methods. Additionally, it will assess the biopolymer hydrogel matrix where the developed NDs and enzymes will be incorporated and immobilized. The equilibrium of the immobilized enzyme will be carefully studied to achieve optimal association and dissociation, aiming to enhance transdermal delivery while maintaining skin health. Moreover, comprehensive bioavailability and cytotoxicity studies, as well as in vitro and ex vivo analyses for in depth characterization of the transdermal delivery of NBCs are planned. By merging biocatalysis and nanomaterials, this project offers a more effective alternative to conventional treatments, including skin cancer, minimizing the ecological impact.

Keywords: enzyme immobilization binding dynamics hydrogels fluorescence microscopy transdermal delivery
On-line, real-time biosensor for monitoring bioprocesses and food production using µBeads sensor technology to optimize production processes and ensure food safety (SpheroScan)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator Open 2024 (HORIZON-EIC-2024-ACCELERATOR-02, 2024)
Start date: 2025-07-01
End date: 2027-06-30
Duration (months): 24.0
Total project cost (EUR): 3516407.5
EU funding (EUR): 2461485.25
Participants: 1
Project status: SIGNED

The food industry is highly competitive, and the stakeholders involved in it are looking for innovations to differentiate themselves from competitors, become more efficient and reduce risks. In this context, food quality, particularly food safety, has attracted significant attention and represents a promising market. Factors affecting growth include an increasing number of foodborne diseases, heightened regulatory attention and the growing adoption of new technologies related to food safety. FluIDect’s SpheroScan® is the first Industry 4.0 compatible sensor for microbial analysis in food production plants, representing a huge breakthrough since the state-of-the-art has been to take samples for subsequent analysis in a laboratory (rapid tests also exist, but only for some contaminants and with limited performance). It is based on a novel approach to label-free bacterial and fungal detection named Fluorescent Resonator Signature (FRS). This will yield major customer benefits, such as short time to result (below 10 minutes instead of several days), identification of specific targets, high sensitivity (1 CFU/ml), quantification of specific targets, and automation. FluIDect will address different stakeholders as potential customers: food producers and farms, food testing labs, and systems integrators. In our discussions and proofs of concept with these stakeholders, we verified their willingness to pay. We will enter the market through food producers and farms to demonstrate the feasibility and benefits of using SpheroScan. Later, we will move on to Food Testing Labs, allowing us to reach many more customers and improve our solution. Subsequently, we will partner with relevant system integrators for food processing equipment, enabling us to cross the chasm and integrate our solution seamlessly into the factory infrastructure. This staggered GoToMarket strategy will facilitate a quick scale-up, establishing us as the reference for pathogen testing in food.

Keywords: food safety testing,biosensor,digitization of processes,online process monitoring,fluorescent resonator signature
Novel 100% automated AI-based optical emissions monitoring system for monitoring, forecasting, and tracking of 400+ hazardous gases and emission-prevention in extended industrial areas in real time (TRACKFELD)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2149000.0
EU funding (EUR): 2149000.0
Participants: 1
Project status: SIGNED

The chemical industry and the energy sector produce thousands of tons of hazardous and environmentally harmful gases every day. Last year, over 50 people died and more than 5,000 people were injured worldwide due to undetected gas leaks. Still, 69% of significant emissions are not detected and there is no technology to locate and quantify these diffuse emissions. With our patented technology, we monitor emissions in real-time via optical analysis in 1 km distance with 360° view. In this project, we develop a novel system -TRACKFELD- that automatically locates, identifies, quantifies, tracks and forecasts 400+ chemical compounds simultaneously. Core innovation is the combination of optical measurements with our self-developed software doing the analysis in 5D (space, time, spectrum) fully automated 24/7. It also allows preventive maintenance of the plant’s equipment. Our modular system will enter the gas emission monitoring market which is expected to reach ~€28 billion by 2028.

Keywords: total emission quantification,goal zero,gas detection,remote sensing,data science,industrial iot,artificial intelligence,machine learning,environmental monitoring,ftir spectroscopy
Decadence for doctoral studies (DECADOCS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom,Italy,Spain,Ireland,Finland,Portugal,Germany,France
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2025-10-01
End date: 2030-09-30
Duration (months): 60.0
Total project cost (EUR): 3717419.76
EU funding (EUR): 3717419.76
Participants: 26
Project status: SIGNED

DECADOCS is a research and training programme which aims to renegotiate common assumptions about decadence that equate it with decay and decline. A more nuanced view of decadence predicated on sustainability, transnationalism, and sensoriality, envisages it as a valuable tool to enrich our understanding of contemporary artistic, media, entertainment, and sociocultural practices. Perceived as ubiquitous in 2025, decadence is linked to a rich and still evolving set of meanings and associations cutting across European societies since the nineteenth century. Its persistent link with crises and their recurrence has a continuing valence today and helps to explain the renewed interest in uncovering its illuminating potential. DECADOCS therefore aims to show how that complex transhistorical, transnational, and trans-linguistic European phenomenon still undergirds arts, media, and sociocultural practices. The examples of architecture, fashion, food and drink, tourism, visual and print cultures, entertainment, and immersive media testify to the presence and positive value of decadence. Firmly anchored in decadence studies as a field of the humanities, DECADOCS' research programme will therefore train a cohort of doctoral fellows, notably by addressing those non-literary, underexplored areas of study, embedding different disciplines in a coherent research programme with clearly defined and linked scientific work packages, bespoke network training activities emphasizing digital dissemination, open access, and outreach to various audiences. Tailored intersectoral training delivered by the most appropriate associated partners (museums, archives, libraries, galleries, and SMBs in fashion conservation and translation) during substantial periods reinforces the research programme's scientific and societal impacts. DECADOCS is the first doctoral network in decadence studies.

Keywords: decadence studies,sustainability,transnationalism,sensoriality,creative arts and industries,media archaeology,translation,print culture,visual culture
Sanative Patches for Advanced Regenerative Engineering of the Heart (SPARE HEART)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Israel
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-07-01
End date: 2026-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

Cardiovascular diseases are the leading cause of death in the world. Because the human heart has effectively no regenerative capabilities, the damage caused by cardiovascular diseases and heart attacks is both cumulative and progressive. The aim of this project is the development of regenerative tissue-engineered cardiac patches, which will revolutionize healthcare by providing patients with a treatment that seeks not to manage their symptoms, but to correct and reverse the underlying damage to the cardiac muscle. While the theory underpinning regenerative cardiac patches is not novel, reaching TRL5/6 by demonstrating proof-of-concept with 3D-printed, thick, fully vascularized, clinically relevant patches would constitute an extraordinary step forward for the field. In this project, we propose to 3D-print thick, vascularized cardiac tissues comprised of functional cardiomyocytes and blood vessel–forming endothelial cells derived from human induced pluripotent stem cells (iPSCs). The tissues will be between ½ -1 cm thick and will require significant levels of vascularization. Following fabrication, tissues will be matured in custom-designed bioreactors and reinforced, rendering them strong enough to be easily handled by surgeons. We then propose to perform cardiac-regenerative surgery in a large mammal model (pigs). This study will serve as a proof-of-concept that will advance the technology from an academic setting to the biotech industry and ultimately into the clinic.