Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
ACTIVE AGEING – RESILIENCE AND EXTERNAL SUPPORT AS MODIFIERS OF THE DISABLEMENT OUTCOME (AGNES)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Finland
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2016-09-01
End date: 2021-08-31
Duration (months): 60.0
Total project cost (EUR): 2044364.0
EU funding (EUR): 2044364.0
Participants: 1
Project status: CLOSED

The goals are 1. To develop a scale assessing the diversity of active ageing with four dimensions that are ability (what people can do), activity (what people do do), ambition (what are the valued activities that people want to do), and autonomy (how satisfied people are with the opportunity to do valued activities); 2. To examine health and physical and psychological functioning as the determinants and social and build environment, resilience and personal skills as modifiers of active ageing; 3. To develop a multicomponent sustainable intervention aiming to promote active ageing (methods: counselling, information technology, help from volunteers); 4. To test the feasibility and effectiveness on the intervention; and 5. To study cohort effects on the phenotypes on the pathway to active ageing. “If You Can Measure It, You Can Change It.” Active ageing assessment needs conceptual progress, which I propose to do. A quantifiable scale will be developed that captures the diversity of active ageing stemming from the WHO definition of active ageing as the process of optimizing opportunities for health and participation in the society for all people in line with their needs, goals and capacities as they age. I will collect cross-sectional data (N=1000, ages 75, 80 and 85 years) and model the pathway to active ageing with state-of-the art statistical methods. By doing this I will create novel knowledge on preconditions for active ageing. The collected cohort data will be compared to a pre-existing cohort data that was collected 25 years ago to obtain knowledge about changes over time in functioning of older people. A randomized controlled trial (N=200) will be conducted to assess the effectiveness of the envisioned intervention promoting active ageing through participation. The project will regenerate ageing research by launching a novel scale, by training young scientists, by creating new concepts and theory development and by producing evidence for active ageing promotion
CEN standard Certified Experts EU-wide qualification and training scheme based on EPBD mandated CEN standards (CEN-CE)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Italy,Belgium,Croatia,Slovakia,France
Call: Construction skills (H2020-EE-2017-CSA-PPI, 2017)
Start date: 2018-06-01
End date: 2020-11-30
Duration (months): 30.0
Total project cost (EUR): 824883.92
EU funding (EUR): 824883.92
Participants: 6
Project status: CLOSED

In order to reach the EU's energy and climate targets, a qualified building workforce is needed. Professionals need to be aware of new upcoming challenges: (e.g. nZEB, renewables, new state of art) and be trained on it. The objective of this proposal is to set up a large-scale qualification and training schemes to increase the skills of HVAC professionals related to the new upcoming challenges. HVAC professionals play an important role in energy efficiency, especially in renovation where HVAC systems are often replaced or upgraded first. The proposed training schemes are based on CEN standards related to the EPBD and mandated by the European Commission. The standards were voted positively in January 2017. The new CEN standards offer innovative approaches and solutions including renewables, economical calculation (cost optimum) and measured energy . To bring them into application, training is urgently needed. Several national calculation methodologies for energy performance of buildings are based on current CEN standards and they have to be replaced by new standards. The proposal is focusing on increased skills of HVAC professionals with direct links to the EPBD and Ecodesign Directive (e.g. Lot1, Lot 2). CEN standards are also used for the common EU voluntary certification scheme requested in the EPBD. The training scheme will be complemented by a qualification scheme. It addresses strong market request, shown by the support of stakeholders of the whole building value chain. Qualification and training based on European standards is an advantage for mutual recognition of qualifications and certifications schemes among different EU Member States. Standardisation is also key to create level playing field conditions for products European wide. The consortium includes standard writers, HVAC professional association and professionals, public authority advisers, universities and is supported by actors of the whole building value chain.

Keywords: qualified building workforce,training on hvac cen standards,new construction,renovation
The genomic signature of rapid coevolution within a wild host-parasite system (Coevolution)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: CLOSED

Parasites infect nearly all forms of metazoan life, and act to shape the evolution of host populations and drive the dynamics of entire biological communities. Parasitism also acts a 2-way street: As host populations evolve in response to selection imposed by their parasites, so too does the parasite evolve in response to its host. This antagonistic coevolution between host and parasite may generate much of the genetic diversity found in natural populations, and is likely a strong driver of local adaptation and population differentiation. Host-parasite coevolution is also of enormous practical concern for human society, as parasites impose considerable costs in respect to agriculture, livestock production, aquaculture, and human health. Unfortunately though, very little empirical evidence is available to evaluate some of the most fundamental predictions of coevolutionary theory, especially in respect to the genomic basis of coevolution, as past studies of antagonistic coevolution have typically been conducted at the phenotypic level, or using simplified host-parasite systems in a laboratory setting. I therefore propose to conduct a direct genome-level investigation of antagonistic coevolution between wild populations of a host (Daphnia magna) and its bacterial parasite (Pasteuria ramosa). This research will capitalize upon recent technical and theoretical advances in the D. magna / P. ramosa system, and will center upon the measurement of interspecies linkage disequilibrium across the genomes of both species. This investigation will be conducted across multiple timescales: A single point in time, across the course of one year, and across a 50-year sediment core time-series. I expect that these experiments will yield direct genomic evidence of antagonistic coevolution in a natural population, a clear test of Red Queen coevolutionary dynamics, and the first genetic time-series of such resolution and duration.

Keywords: antagonistic coevolution,aquatic ecology,host parasite interactions,genomic basis of infection,red queen
Women In Science Night: Celebrate science, sustainability and gender diversity: Women researchers on earth, in the oceans, in space ... and in Brussels (WISENIGHT)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European researchers' Night
Action type: Marie Skłodowska-Curie actions
Countries involved: Belgium,Belgium
Call: European Researchers' Night (H2020-MSCA-NIGHT-2020bis, 2020)
Start date: 2021-05-01
End date: 2022-04-30
Duration (months): 12.0
Total project cost (EUR): 209081.25
EU funding (EUR): 209081.25
Participants: 7
Project status: CLOSED

With this project, we aim to bring researchers closer to the general public and stimulate the interest in science careers among young people. Citizens of all ages will be able to discover research focusing on three natural environments permitting them to exchange ideas and experiences with scientists. The events take place in various inspiring locations in Brussels, capital of EU, so it is also a place-discovery of historic and natural landmarks to conduct research. The unique features of the WISENIGHT proposal are: Focus on gender diversity in scientific careers by showcasing women role models; Link between sciences and the arts by movie screenings and integrating a photo exhibition created for the occasion; Inclusive in all its aspects by involving many types of research actors in the local ecosystem (French and Dutch) and addressing a diverse public (all ages, all socio-economic backgrounds). To achieve this, we will organise more than eighty activities engaging the audience like Demonstrations focused on sustainability and climate change; Arts & Science exhibitions portraying female scientists, Workshops focusing on new trends in science and technology such as water and solar power & food of the future, A movie aiming to present issues related to gender equity. Our awareness campaign will be one of the successful key points in this project. A dedicated media plan has been designed and a specialized press office will be involved to promote the activities in the most important newspapers and TV channels at national level, also promoting our outreach events throughout the whole year on social media channels (Facebook, Twitter, Instagram). In order to evaluate the impact of our project, we will analyse the target audience reached during the WISENIGHT; measure the increase of knowledge and promotion of the researcher's figure; evaluate how much and which media have influenced the dissemination activities; and understand the level of appreciation of the events.

Keywords: natural sciences,space sciences,science outreach,science education,gender diversity,sustainability,european research and innovation
Make Net Zero Energy refurbishments for houses a mass market reality (TRANSITION ZERO)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Market uptake of energy innovation
Action type: Coordination and support actions
Countries involved: Belgium,France,France,France,Netherlands,Netherlands,United Kingdom,United Kingdom
Call: Increasing energy performance of existing buildings through process and organisation innovations and creating a market for deep renovation (H2020-EE-2015-3-MarketUptake, 2015)
Start date: 2016-03-01
End date: 2018-12-31
Duration (months): 34.0
Total project cost (EUR): 3570438.75
EU funding (EUR): 3570438.75
Participants: 10
Project status: CLOSED

TRANSITION ZERO will make Net Zero Energy (E=0) refurbishments a market reality in the UK, France and The Netherlands. Energiesprong brokered a deal between housing associations and builders to refurbish 111,000 houses to E=0 levels in the Netherlands of which the roll-out will be further supported. Building on the same methodology and the inspiring example, a similar innovation trajectory will be facilitated in the UK and France through two deals of 5,000 houses per market and building a pipeline of more demand. TRANSITION ZERO will organize massive demand for a E=0 refurbishment proposition from social housing organizations, facilitates financers and governments to tune their financing products and regulations towards this product and challenges the construction sector to start an ambitious innovation process to deliver the proposition. The massive demand, the security that there will be finance available and an enabling regulatory environment will de-risk the innovation investment for the builders. The problem to solve to get these propositions to the market is not around technical challenges requiring breakthroughs. The problem is a set of market conditions that are not set right for the innovation process in the construction sector to take off. The consortium is therefore convinced that the market needs a new and independent actor to drive and coordinate actors to jointly develop all parts of the market solution in parallel. This independent actor is the TRANSITION ZERO market development team. The consortium has the partners and supporters to realize the objectives set out: National governments and specialized agencies; the three key financiers of social housing in the three countries; the European en all national umbrella organizations for social housing and 19 individual social housing organizations managing over half a million houses.

Keywords: net zero energy,refurbishment,early market
The first ground stations network enabling real-time, cost-effective, and easy access to micro/nanosatellite data (LEAF LINE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Action type: SME instrument
Countries involved: Italy
Call: SME Instrument (H2020-SMEINST-1-2015, 2015)
Start date: 2015-09-01
End date: 2016-02-29
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

The objective of the LEAF LINE project is to capture the value of the blossoming nano/microsatellites Space market, offering a complete service pack for telecommunication able to maximise the connection time/data transmission rate with satellites. Nano/microsatellites are opening up a range of new opportunities in the Earth Observation industry: they can perform many operations that, until few years ago, were carried only by large satellites, but at a fraction of the cost. Lots of new satellite operators (e.g. insurance companies, geologists, food companies, environmental agencies, research centers, etc.), are all asking for reliable, cheap, up-to-date and frequent data from Space. However, most of the telecommunications between microsatellites and the Earth are performed by point-to-point link with a single ground station (GS) and the standard connection is limited to around 10-50 minutes per day. This results in a poor usage of the GS, which remains inactive for most of the day. The LEAF LINE project aims to set-up a network of ground stations for managing satellite data, with substantial increase of connection time (up to 7 times for each satellite) and optimized usage of each GS (up to 12 hours a day). The service will be based on the following components: 1. A multi-protocol ground station network, which implements both the low-performance frequencies, VHF-UHF, and S-band and X-band, allowing an easy switching to the band needed for communicating with all the satellites in orbit. 2. An on-board device optimized for the LEAF LINE network, ensuring the best connection performance in line with the customer needs. 3. The overall software infrastructure that coordinates the network of GSs by Leaf Space, ensuring proper tracking of the satellites, and the handshake between several GSs serving the same satellite. The software allows coordinating the GSs with the satellite constellation, thus increasing the overall transmission time for each GS up to 12 hours a day.

Keywords: micro and nanosatellites,space data,groundstation network
ICFOstepstone PhD Programme for Early-Stage Researchers in Photonics (ICFOstepstone)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Co-funding of regional, national and international programmes (COFUND)-Doctoral programmes
Action type: Marie Skłodowska-Curie actions
Countries involved: Spain
Call: Marie Skłodowska-Curie Co-funding of regional, national and international programmes (COFUND-DP) (H2020-MSCA-COFUND-2015, 2015)
Start date: 2017-07-01
End date: 2023-03-31
Duration (months): 69.0
Total project cost (EUR): 3924000.0
EU funding (EUR): 1962000.0
Participants: 1
Project status: CLOSED

ICFOstepstone is being proposed as an evolution of the current PhD-programme, offering competitive fellowships, paired with dedicated training actions within the chosen research field as well as for acquiring transferable skills, implementing mobility-actions in form of compulsory secondments at partner institutions in academia and industry alike, aiming at an integrated PhD aligned with the objectives in H2020. We aim at promoting an international research environment where traditional boundaries between fields and sectors are crossed and multidisciplinary projects undertaken, therefore aiming at covering the triple “i” dimension. It is expected that the award of a Fellowship under the proposed Programme will significantly boost the Fellow’s career perspectives and their connections, enabling a diverse career path in the most important institutions worldwide of their chosen sector, therefore guaranteeing a smooth and successful transition to their next career step. The ICFOstepstone is considered to be a natural advancement from the COFUND programmes ICFO launched in the past, in terms of now expanding our efforts to the postgraduate level, to establish a long-term talent pipeline at any career level. This COFUND action therefore proposes a change in the focus group of potential recipients from the Experienced Researchers to Early Stage Researchers. Also, with ICFOstepstone, the excellence approach not only aims at an enhancement of the Recruiting & Hiring Life-Cycle but also at an enhancement of the Career Development Plan. As shown in the proposal, ICFO has the necessary expertise to implement and develop the programme due to its broad and proven track record in the management of international research and education programmes. The proposal is also in line with current strategical ICFO HR and Education Objectives: working towards the implementation of the “HR Strategy for Researchers” and towards further strengthening and enlarging our training programme.

Keywords: physics,biophotonics,quantumphotonics,nonlinear photonics,nanophotonics,mobility,training,transferable skills,secondments,early researchers,international,intersectoral,interdisciplinary
Can Direct Democracy Be Scaled? The Promise of Networked Democracy and the Affordances of Decision-Making Software (SCALABLE DEMOCRACY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-01
End date: 2018-08-31
Duration (months): 24.0
Total project cost (EUR): 180277.2
EU funding (EUR): 180277.2
Participants: 1
Project status: CLOSED

The project investigates the recent rise of networked forms of political participation in Europe. It does so by analyzing a set of political parties—namely, Podemos in Spain, the Five Star Movement in Italy, and the Pirate Parties in Sweden and Germany—that encourage the participation of all citizens in political deliberation through the use of networked media. More specifically, the research focuses on the technical affordances and uses of the decision-making software adopted by these parties to advance a new idea of democracy, which mixes elements of representative democracy and direct democracy. Software such as LiquidFeedback, Agora Voting, Appgree, Loomio, AdHocracy, and DemocracyOS allow users not only to select party delegates and representatives but also to submit, discuss, and vote their own policy proposals. On the one hand, these emerging practices can be seen as an extension to the electronic realm of participatory decision-making processes associated with recent social movements for “real democracy.” On the other hand, the existence of party delegates, the adoption of majority voting, and the choice of participating in the elections signal that these parties acccept representative democracy, even as they vow to transform it from within. By bringing together different theoretical perspectives in media studies, political theory, and social movement studies, the research maps how these different conceptions of democracy are reflected in the design of decision-making software. A first set of semi-structured interviews asks software developers to discuss the political values embedded in the software—e.g., whether the software privileges consensus or majority rule, temporary delegation or representation, public or anonymous voting. A second set of interviews asks users whether they are aware of the values embedded in the software, have considered their limitations, have suggestions on how to improve them, or see online deliberation as inherently flawed.

Keywords: digital democracy,networked democracy,decision making software,internet parties
Extracellular vesicle-mediated delivery of long non-coding RNA: Implications for vascular repair and regeneration (EV-LNC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-08-01
End date: 2019-07-31
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Background: The concept of extracellular vesicles (EVs) has drastically changed from the initial non-functional debris to the current of key mediators of paracrine signalling. The cargoes of EVs comprise all kinds of macromolecules, and recent evidence has demonstrated the presence of long non-coding RNAs (lncRNAs) in such vesicles. These RNA molecules have numerous potential regulatory functions and results obtained so far guide us to presume a determinant role in vascular cell differentiation, proliferation and repair. Besides, the increasing data emerging in the field are significantly changing the way in which we interpret molecular mechanisms driving cardiovascular diseases and offers a brand new set of molecular targets for therapy. For all these reasons, study of lncRNAs in vascular biology and disease is state-of-the-art. Objectives: The main aim of this project is to study extracellular vesicle mediated cell-to-cell communication between human smooth muscle cells and endothelial cells, evaluate its relevance in vascular injury in an in vitro model of pulmonary arterial hypertension, and determine the significance of long non-coding RNA in this crosstalk. Methodology: For imaging EV transfer among vascular cells, we will use a pioneer approach based on Cre-loxP recombination which results in a fluorescent colour switch of cells upon EV uptake. Cells will then be sorted according to fluorescence by flow cytometry and analysed by cutting-edge proteomics and bioinformatics, in order to elucidate intercellular signalling triggered by EV transfer. The lncRNAs present in EVs will be analysed by RNA-Seq. Mechanistic insight of enriched lncRNAs in EVs will be evaluated using gain- and loss-of function approaches in vascular cells using lentiviral vectors and GapmeRs/siRNAs, respectively. Integration of all these analyses will provide key information to define implications of EV-mediated delivery of lncRNA for vascular repair and regeneration.

Keywords: extracellular vesicles,non coding rna,lncrna,pulmonary arterial hypertension,vascular,cell to cell communication