Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Reshaping the future of laser-based manufacturing: Advancing our beam steering technology INLEAP FASTLIGHT for efficient and sustainable production in Europe (ReLIGHT EUROPE)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

INLEAP Photonics GmbH provides innovative pixel-based laser technology (INLEAP FASTLIGHT) to the markets, to significantly accelerate manufacturing processes essential for e.g. the battery-cell or photovoltaic-module production by a factor of up to 10. As part of a government-funded project (EXIST research transfer), we have developed our technology to market readiness (TRL 5). In September 2024, our product will be evaluated with three pilot customers to move towards TRL 6. We seek additional funding after EXIST to continue developing our system, grow our company, and realize our vision of reshaping laser-based manufacturing in Europe. Our goal for the next years, and thus for this proposal, is to advance our product (development) to reach TRL 9. This will enable us to enhance laser-based manufacturing in the long term and fundamentally rethink how laser beams are used in production environments. We request funding for: • Reach TRL 9 with our FASTLIGHT product line • Further research and development (e.g. AI-based control software) • Production scaling up • Revenue expansion INLEAP Photonics as a company and our product “FASTLIGHT” align perfectly with the EIC mission of supporting breakthrough innovations that drive Europe forward. Our technology can significantly improve and strengthen productivity and sustainability in Europe's industries, reshaping the future of laser material processing. With our technology we are enhancing Europe's production capabilities by substantially improving laser-based production for our B2B customers, thereby creating a more sustainable future. The potential of our technology, the company and the founders’ commitment ensure a successful and lasting success of the company and for the EU industry. However, the reach into the markets, the scale-up and production pose a high technological and financial risks. The alignment with EU goals, make EIC funding the perfect fit.

Keywords: ultra high speed,laser based production,disruptive,innovative,sustainable,resource saving,manufacturing,laser,battery cell production,additive manufacturing,laser beam steering,pixel based
HaloDrive: Reimaging Electric Propulsion for Zero-Emission Aviation (ROGERSEV)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: United Kingdom
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Aviation in the EU contributes 3.8% of total CO2 emissions and 13.9% of transport emissions, second only to road transport in greenhouse gases. With air travel growing at a rate of 4-5% annually, emissions could triple to over 2.7B tonnes by 2050. Meeting the IEA's Net Zero Emissions by 2050 Scenario demands urgently reducing the industry's carbon footprint. RogersEV's HaloDrive electric propulsion system is a revolutionary solution. It employs a groundbreaking rim-driven ducted propeller system powered by a core-less circumferential flux motor architecture, achieving efficiencies exceeding 80%. This surpasses the 26% efficiency of traditional fuel systems and the 52% efficiency of conventional electric systems. By integrating advanced motor technology, cutting-edge energy storage solutions, and optimized system integration, HaloDrive sets new standards in performance, durability, and operational economics, paving the way for practical zero-emission flight. When seamlessly integrated with state-of-the-art battery and material advancements, HaloDrive enables customizable vehicle development, making it ideal for both Urban Air Mobility and Regional Air Mobility markets. This innovative propulsion system significantly reduces CO2 emissions and noise, extends range for the same battery size, decreases battery requirements for the same range, and prolongs battery life cycles. RogersEV's HaloDrive represents a pivotal advancement in sustainable aviation, addressing the industry's need for high-efficiency, low-noise, and environmentally friendly propulsion solutions. By driving industry-wide innovation and advocating robust regulatory measures, HaloDrive promises to revolutionize air travel, aligning with global environmental goals and shaping the future of aviation. We are seeking €2.5M in EIC grant funding to expedite the development and commercialization of our electric propulsion systems, enhancing market readiness and leadership in sustainable aerospace technologies.
Glycan Mimetics for Cell Glycocalyx Reconstitution: a polymer chemist’s approach to fight infection (GLYMCE)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2024-02-01
End date: 2029-01-31
Duration (months): 60.0
Total project cost (EUR): 1994024.0
EU funding (EUR): 1994024.0
Participants: 1
Project status: SIGNED

Objective: The aim of GLYMCE is to understand how carbohydrates and their assemblies are recognized by pathogens to drive infections. The identified molecular patterns will be transferred to biomimetic glycopolymer materials to extend the arsenal for the fight against infections. Carbohydrates are not just sweet, they are crucial in various biological interactions: Cell surfaces are covered in carbohydrates, the glycocalyx, that governs contact with pathogens such as viruses and bacteria. A class of carbohydrates critical for pathogen attachment and infections are glycosaminoglycans (GAGs). GAGs are highly diverse polysaccharides already used in medicine (e.g., heparin against thrombosis). The potential of GAGs in fighting viral and bacterial infections has been recognized in biology and medicine, but, as of today, there are no GAG-based drugs used for this purpose. A key limitation is insufficient knowledge about the mode of action of GAGs within the complex ensemble of the glycocalyx: How does the display of GAGs within the glycocalyx affect their pathogen interactions? GLYMCE wGLYMCE will tackle this question from the polymer chemist’s point-of-view: taking a bottom-up approach to prepare GAG mimetics (level 1); assemble glycocalyx mimetics and study their spatial organization of GAGs upon pathogen binding (level 2); reengineer the glycocalyx of living cells to understand the factors governing infection (level 3). This is only now possible through recent synthetic tools developed by my lab enabling GAG mimetics with controlled sequence, molecular weight, chain conformation, architecture and sulfation patterns – all parameters known to critically impact the affinity and selectivity of GAGs. Overall, by taking a radically different approach informed by chemical biology and brought to life by polymer chemistry, mechanisms for GAG-mediated pathogen attachment will be derived and applied to develop new materials and strategies to detect, prevent and treat infections.

Keywords: sequence defined polymers,glycopolymers,biomolecular interactions,molecules against infection
FortifyIQ – Elevating Low-Cost IoT to the Top Security Level with AI Assets Assured (IoT security)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

FortifyIQ – Elevating Low-Cost IoT to the Top Security Level with AI Assets Assured In this project, we aim to secure low-cost and low-power IoT devices against sophisticated physical attacks, including side-channel and fault injection attacks, and provide security for AI Assets. Our approach focuses on developing a comprehensive hardware root of trust (RoT) subsystem, utilizing FortifyIQ’s groundbreaking algorithms. This subsystem is designed to provide robust defence mechanisms while maintaining the affordability, performance, and low energy consumption critical for IoT devices.

Keywords: iot,low cost iot,low power iot,ai,ai assets,secured
Explainable AI for Molecules - AiChemist (AiChemist)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Sweden,France,Denmark,Netherlands,Italy,Switzerland,Spain,United States,Korea, Republic of,Finland
Call: MSCA Doctoral Networks 2022 (HORIZON-MSCA-2022-DN-01, 2022)
Start date: 2023-09-01
End date: 2027-08-31
Duration (months): 48.0
Total project cost (EUR): 3728581.2
EU funding (EUR): 3028356.0
Participants: 29
Project status: SIGNED

Optimising biological activity and physico-chemical properties, while minimising their toxicity, are objectives when developing new compounds in chemical industries. Advanced machine learning (AI) methods are indispensable to this process. They are also increasingly used in environmental chemistry to identify compounds damaging to the environment and humans. Traditional machine learning (ML) methods provide reliable predictions though only for compounds similar to the training set, thus defining their applicability domain (AD). Emerging representation learning approaches can efficiently approximate the physical interactions of molecules with an accuracy comparable to physics-based methods in only fractions of time. Models based on these representations should have much larger AD due to pre-training on large chemical sets of theoretical values. Here we will develop and benchmark representation learning approaches, addressing their accuracy and ADs, using public and in-house data for endpoints ranging from chemical reactions to toxicity. While explainable AI (XAI) methods are actively developing in the ML community, there is a gap with their use in chemistry, i.e. there is a need to translate their results to the end users, chemists and regulatory bodies. Since the research program is tightly coupled with the target users - large companies, regulatory agencies and SMEs - it provides a clear path for technology transfer from academia to industry. AiChemist will provide structured training to its fellows through a combination of online courses and schools, strengthening European innovation capacity in the education of specialists in AI methods. The fellows will receive comprehensive training in transferable skills. The complementary expertise and strong commitment of the partners make this ambitious innovative research program realistic via the proper allocation of individual tasks and resources, as described below.

Keywords: explainable ai,xai,representation learning,chemical reactions,reactivity,quantum chemistry,computational toxicology,natural language processing,nlp,transformers,transfer learning
PAST & FUTURE MILLET FOODWAYS (MILWAYS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Study of the Human Past
Panel description: Archaeology and history
Countries involved: Lithuania
Call: ERC CONSOLIDATOR GRANTS (ERC-2022-COG, 2022)
Start date: 2023-06-01
End date: 2028-05-31
Duration (months): 60.0
Total project cost (EUR): 1999489.0
EU funding (EUR): 1999489.0
Participants: 1
Project status: SIGNED

Crop diversification critically mitigates agricultural risk for humanity. Identifying the environmental and cultural factors influencing the adoption and abandonment of staple foods through time is essential to an informed discussion about present-day food security and adaptation to a changing global climate. Past studies on ancient agriculture have identified the routes and timing of primary crop dispersals, but we possess a remarkably narrow understanding on how and why new foods were integrated and later abandoned by societies, and why certain crops remained restricted to distinct geographical regions. The MILWAYS project is perfectly poised to fill this alarming gap in knowledge, though a multi-faceted investigation of a specific crop - broomcorn millet (Panicum miliaceum) - which, due to its unique biochemical properties, is traceable across space and time. Making use of multi-disciplinary cutting edge research methodologies, MILWAYS will bridge a large geographic territory and track the earliest millet dispersals across eastern-central Europe from the mid. 2nd mill. BCE onwards all the way to past millet cultivation limit. MILWAYS will utilize the high carbon isotope values of millet, resulting from its C4-photosynthetic pathway in conjunction with the distinct miliacin biomarker in order to identify its consumption, with respect to shifting climates, human mobility, demographic categories of sex, age and changes of plant use across historical times. Along with transforming the approaches on how we study past agriculture, MILWAYS will: a) Identify the interplay of cultural versus climatic factors in past staple food adoption and abandonment; b) Develop novel methodologies to the study of past diets and climates that are highly transferable to the study of other crops; c) Better understand millet environmental adaptation in northern latitudes; d) Create models of past and future crop exploitation strategies.

Keywords: ancient agriculture,plant dispersal,millet
Toxic Free metallization process for plastic surfaces (FreeMe)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Increased Autonomy in Key Strategic Value Chains for Resilient Industry
Action type: Research and Innovation actions
Countries involved: Italy,Greece,Spain,Türkiye,Israel
Call: Safe- and sustainable-by-design metallic coatings and engineered surfaces (RIA) (HORIZON-CL4-2021-RESILIENCE-01, 2021)
Start date: 2022-06-01
End date: 2026-05-31
Duration (months): 48.0
Total project cost (EUR): 4834592.5
EU funding (EUR): 4834592.0
Participants: 12
Project status: SIGNED

Technological advancement has significantly transformed plating methods by introducing metal coatings on plastic substrates. Plating on plastics (PoP) has emerged as an effective solution in a wide range of applications in the automotive, aerospace and home appliances industry. There is a high preference for plating on plastic in the automotive industry, owing to its light weight, cost effectiveness and corrosion resistance. In the automotive industry, it not only adds aesthetic value but also helps in increasing fuel efficiency by reducing the overall vehicle weight. Decorative chrome, copper and nickel plating is quite popular on various interior and exterior plastic parts such as knobs, handles, logos, emblems, trims, etc. ABS, PC, PET, Nylon, and PEEK are widely used polymers in plastic plating. However, the current processes for PoP present some significant disadvantages related to environmental sustainability, occupational safety and quality of coatings i.e the use of hexevalent chromium in the etching process and the use of Palladium in the activation step. FreeMe project proposes two revolutionaries approaches for the metallization of polymeric (plastic or resins) surfaces without the use of hexavalent chromium and palladium. The first technology is based on the use of resins (e.g. epoxy-acrylate resins) with the additions of suitable nickel based precursors. This composite resin can be deposited uniformly in the surface of the plastic object either by spray deposition methods or other simple deposition methods. The nickel precursors are afterwards reduced utilizing appropriate reduction agents (e.g. NaBH4) creating the necessary nuclei for the next step of electroless deposition for the formation of the conductive layer.

Keywords: plating on plastics,etching,activation,metallization,bio based resins,adhesion
Gene Therapy of Rare Diseases (GetRadi)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Denmark,Germany,Czechia,Italy,United Kingdom,Sweden,Netherlands
Call: MSCA Doctoral Networks 2021 (HORIZON-MSCA-2021-DN-01, 2021)
Start date: 2022-09-01
End date: 2026-08-31
Duration (months): 48.0
Total project cost (EUR): 3149220.34
EU funding (EUR): 2785809.6
Participants: 15
Project status: SIGNED

More than 300 million people worldwide are suffering from more than 6000 rare diseases. Nearly all of these rare diseases are caused by a single inherited mutation and cannot be treated effectively. Repair of the defective gene by gene editing is the only possible curative therapy. However, only for very few rare diseases such gene editing therapy has reached the clinic. The “Gene therapy of Rare Diseases” (GetRadi) consortium aims now to contribute strongly to the establishment of more gene therapies for rare diseases. This will be accomplished by training of future leaders in gene therapy of rare diseases preforming ambitious research projects, with the following objectives: (i) Improving transfer of genome editing tools to target cells, (ii) improving gene editing efficiency, and (iii) improving safety of gene therapy. Strong participation of the pharmaceutical industry to research projects and training, development of novel in vitro and in vivo models for rare diseases to test gene therapies in relevant settings, and application of several unique genome editing tools developed by the applicants to the treatment of rare diseases are hallmarks of the network. GetRadi brings together strong industrial beneficiaries (AstraZeneca, Miltenyi Biotec) supervising 3 ESR, highly innovative academic beneficiaries supervising 7 ESR, 3 additional industrial partners, and 4 student enrolling universities. Professional outreach training with access to widely used social media channels will be provided by the partner “European Consortium for Communicating Gene and Cell Therapy Information”. Complementary unique expertise that is spread efficiently by network-wide training and secondments, excellent quality of supervision and intersectoral interactions, innovative transferable skill training, and efficient consortium management will result in an exceptional training of future leaders in gene therapy of rare diseases.

Keywords: gene therapy,rare diseases,crispr genome editing
Arctic Pollution in a One Health perspective - from complex challenges to sustainable solutions (ArcSolution)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Clean Environment and zero pollution
Action type: Research and Innovation actions
Countries involved: Norway,Finland,Denmark,Greenland,Germany,Switzerland,China,Canada,Faroe Islands
Call: Tackling human and climate change induced pollution in the Arctic - building resilient socio-ecological systems (HORIZON-CL6-2023-ZEROPOLLUTION-01, 2023)
Start date: 2024-08-01
End date: 2028-07-31
Duration (months): 48.0
Total project cost (EUR): 6598877.5
EU funding (EUR): 6598877.5
Participants: 15
Project status: SIGNED

The Arctic is undergoing rapid changes. Multiple stressors such as climate change and pollution from local and remote sources affect human life, wildlife and the ecosystems of the Arctic. These are inseparably connected and require a holistic approach to analyses and assessments of pollution issues, and to their solutions. Using this One Health approach, ArcSolution will provide knowledge and mitigating solutions, co-created with the people of the Arctic. The Arctic is home to a variety of Arctic communities. To capture this diversity, ArcSolution will work in four Arctic locations, i.e. Northern Finland, Svalbard, Northern Norway (Tromsø) and Greenland, integrating local and Indigenous knowledge with environmental, health, technical and social science research in a One Health approach. The One Health framework will be instrumental in identifying knowledge and data gaps, and in synthesizing the information generated and collected in ArcSolution. In addition to scientifically relevant priority pollutants (e.g. per-/polyfluorinated alkylated substances, mercury, (micro)plastics and their additives, and key pathogens), ArcSolution will provide room for research and citizen science projects on locally prioritized issues. We will study pollution from local and remote sources in a climate change context, pollutant accumulation in food webs and human exposure. We will also evaluate current and predict future impacts of these pollutants on Arctic ecosystems and human health. Together with the local communities, we will develop solutions in the fields of circular economy, technology and chemicals management. Our results will be used in education programmes at Arctic schools already connected to ArcSolution. They will be communicated to policy-makers, industry and the scientific community. The One Health-based knowledge will strengthen the knowledge base and contribute to sustainable preventive actions for human life, wildlife and the ecosystems in the Arctic.

Keywords: one health solutions mitigation climate change