Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Thoracic injury assessment for improved vehicle safety (THORAX)

Framework: FP7 — Cooperation
Programme: Transport (including Aeronautics)
Destination: Sustainable surface transport (INCLUDING THE �EUROPEAN GREEN CARS INITIATIVE�)
Action type: Collaborative project
Countries involved: Germany,Sweden,Germany,France,Germany,Netherlands,Spain,United Kingdom,France,Germany
Call:  (FP7-SST-2007-RTD-1, 2007)
Start date: 2009-02-01
End date: 2013-04-30
Duration (months): 51.0
Total project cost (EUR): 5052558.0
EU funding (EUR): 2968850.0
Participants: 12
Project status: CLOSED

About 41,600 people were killed and more than 1.7 million injured in European road accidents in 2005. Although the number of road fatalities has declined by more than 17% since 2001, more efforts will have to be made if the EC's targets on reduction of road fatalities and injuries are to be met. The THORAX Project will focus on reduction and prevention of thoracic injuries, one of the dominant causes for fatalities and injuries in car crashes. The objective of THORAX is to develop the required understanding in thoracic injury mechanisms and to implement this into numerical and experimental tools that will enable the design and evaluation of advanced vehicle restraint systems that offer optimal protection for a wide variety of car occupants. In order to maximise the safety benefits gained from new vehicle technology for different genders, ages and sizes, these tools will have to be more sensitive to the in-vehicle occupant environment than what is the case today. THORAX mobilises the European research community and car industry to study real world loading conditions and related injury mechanisms given the variation in occupant characteristics and system functionalities offered by modern restraint systems. The gained know-how will be implemented in hardware and software demonstrators that will be evaluated for their added potential on restraint optimisation. THORAX aims to stimulate the introduction of new technologies in vehicles to further reduce road fatalities and injuries to car occupants in Europe and make the traffic safer for young and older drivers. The project also aims to increase the level of competitiveness of the European automobile industry. Safety is a proven selling point, as underlined by a substantial involvement of European car industry in THORAX. The developed tools will be forwarded for usage in design of lS vehicle systems and assessment procedures of such systems. For this purpose THORAX will cooperate with related projects, as defined in a CSA

Keywords: thoracic injuries,chest injury,dummy,biomechanics,atd,assessmet methods
SUpport for Policy RElevant Modelling of Agriculture (SUPREMA)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Coordination and support actions
Countries involved: Spain,Austria,Germany,Germany,Sweden,Belgium,Netherlands
Call: Better understanding the challenges facing agriculture and the impacts of policies - A European platform to support modelling in agriculture (H2020-SFS-2017-1, 2017)
Start date: 2018-01-01
End date: 2020-06-30
Duration (months): 30.0
Total project cost (EUR): 999823.75
EU funding (EUR): 999823.75
Participants: 7
Project status: CLOSED

Impact assessments in the areas of agriculture are (partly) based on projections delivered by models. Sectoral policies are becoming more and more interrelated. Hence, there is a need to improve the capacity of current models, connect them or redesign them to deliver on an increasing variety of policy objectives, and to explore future directions for agricultural modelling in Europe. SUPREMA comes to address this challenge by proposing a meta-platform that supports modelling groups linked already through various other platforms and networks. SUPREMA should help close the gaps between expectations of policy makers and the actual capacity of models to deliver relevant policy analysis. The SUPREMA model family includes a set of ‘core models’ that are already used in support of key European impact assessments in agriculture, trade, climate and bioenergy policies. The meta-platform, the enhanced linked system of existing core models and some key applications melt down in a Roadmap for future directions for agricultural modelling in Europe. The project has four coherent objectives: 1. A SUPREMA roadmap of future directions for modelling will be developed. 2. An enhanced and strengthened SUPREMA model family will be created. 3. Future directions of modelling in agriculture will be explored and tested. 4. A SUPREMA meta-platform will be established, to share and discuss the findings of the work with existing model platforms, research communities, and policy makers. The objectives of SUPREMA are iterative in nature and involve strong engagement with policy makers, and interaction with the scientific community, at the different stages. The models included in SUPREMA cover different spatial scales of analysis, agricultural activities, representation of technologies, but also different aspects of its market environment as well as multiple policies affecting agriculture directly or indirectly.

Keywords: climate change,upstream and downstream sectors
Later Life Intimacy: Women’s Unruly Practices, Spaces and Representations (LiLI)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: The Social World and Its Diversity
Panel description: Sociology, social psychology, social anthropology, education sciences, communication studies
Countries involved: Belgium
Call: ERC Starting Grant (ERC-2019-STG, 2019)
Start date: 2020-05-01
End date: 2026-04-30
Duration (months): 72.0
Total project cost (EUR): 1486000.0
EU funding (EUR): 1486000.0
Participants: 1
Project status: SIGNED

Almost half a century ago, Simone de Beauvoir (1970) denounced what she called the ‘conspiracy of silence’ in public and scholarly debates about women growing older. Little has changed since then. In spite of the expanding number and proportion of older women in the population and the changing cultural norms regarding sexuality, older women are still often overlooked in research, and their sexuality in particular is still a taboo. Older women are supposed to become asexual and when their sexuality is considered, it is interpreted within a medicalized and phallocentric framework that starts from young adult standards. So far, social sciences and humanities have failed to develop a viable alternative to this line of thinking. The proposed project aims to rectify this significant gap in research and break the silence around older women and sex. A multi-disciplinary team of scholars with expertise in anthropology, social geography, cultural studies and feminist philosophy will collaborate and tackle challenging research questions in order to acquire a fundamentally new, affirmative understanding of women’s later life sexuality. A radical multi-method ethnographic research methodology will be developed, (1) based on long-term participant observation in various settings and (2) with a specific focus on ‘unruly’ sexual strategies of older women across different social categories. By uncovering counter-hegemonic knowledge of older women—knowledge that usually stays under the radar of academic attention—the project has great potential to revolutionize how we look at women, old age, and sex. A shift in thinking is needed because the prevalent conceptualizations are blatantly oppressive for older women. Moreover, the project’s methodological-theoretical design that brings older women’s subversive sexual strategies to the forefront of research has also the potential to open the way for radical changes in feminist theorizations of intersectional power, sexual desire and ageing.

Keywords: gender,sexuality,embodiment,ageing,feminist ethnography,intersectionality
The Pancreas Regulome: From causality to prediction of non-coding mutations in human pancreatic diseases (ZPR)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Portugal
Call: ERC Starting Grant (ERC-2015-STG, 2015)
Start date: 2016-06-01
End date: 2021-12-31
Duration (months): 67.0
Total project cost (EUR): 1497520.0
EU funding (EUR): 1497520.0
Participants: 1
Project status: CLOSED

Several human pancreatic diseases have been characterized, being the diabetes the most common. Like others, this genetic disease is related to disrupted non-coding cis-regulatory elements (CREs) that culminate in altered gene expression. Although Genome Wide Association Studies support this hypothesis, it’s still unclear how mutations on CREs contribute to disease. The translation from the “non-coding code” to phenotype is an exciting and unexplored field that we will approach in this project with the help of the zebrafish as a suitable animal model. We aim to uncover the implications of the disruption of pancreas CREs and how they contribute to diabetes in vivo. For this we will study transcriptional regulation of genes in zebrafish. The similarities between zebrafish and mammal pancreas and the evolutionary conservation of pancreas transcription factors (TF) make it an excellent model to approach and study this disease. In this project we will characterize the zebrafish insulin producing beta-cell regulome, by determining the active CREs in this cell type and their bound TFs. Then we will compare this information with a similar dataset recently available for human beta-cells, to define functional orthologs in these species. Selected CREs will be tested by in vivo gene reporter assays in zebrafish, focusing on those functionally equivalent to human CREs where risk alleles have been associated with diabetes or those regulating genes involved in diabetes. Later these CREs will be mutated in the zebrafish genome to validate their contribution to diabetes. Finally we will translate this to predict new human disease-associated CREs by focusing on the regulatory landscape of diabetes-associated genes, without the need of having countless patients to uncover them. With this project we will create a model system that will allow the identification of new diabetes-associated CREs, which might have a great impact in clinical management of this epidemic disease.

Keywords: pancreas regulome,diabetes,enhancers,beta cells,zebrafish,cis regulatory elements,genome wide association studies,chip seq,atac,4c seq,crispr,cas9,pancreatic transcription factors
Cost-effective Combined Heat and Power generator for camping vans (CHeaP)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: SME instrument
Countries involved: Italy,Netherlands
Call: Boosting the potential of small businesses for eco-innovation and a sustainable supply of raw materials (H2020-SMEINST-2-2015, 2015)
Start date: 2015-08-01
End date: 2017-07-31
Duration (months): 24.0
Total project cost (EUR): 752462.5
EU funding (EUR): 526723.75
Participants: 2
Project status: CLOSED

Camper vans allow being autonomous as regards all services and comforts needed, however, the power supply is often a limitation: to overcome this problem camper vans generally dispose of supplementary batteries for services, mainly necessary when the vehicle is stationary and the engine is switched off, which unfortunately become exhausted after only a few hours of use. The present project aims at developing (and then commercializing) a new electricity generator for camping vans, which compensates for the drawbacks and overcomes the limitations of the state of the art solutions currently on the market, through proposing a completely silent system (19Db at 1mt) with limited CO2 emissions (30% less than gasoline generators). The CHeaP generator will be a green, silent, reliable, cost-effective and versatile solution for the camping vans. With the CHeaP project activities, Mobil Tech (an IT SME) aims at optimizing and industrializing the generator prototype they have already developed in the few last years, opening a new big opportunity to expand the company business in central and northern Europe (with the support of Vadac, a well-known SME from The Netherlands). The CHeaP proposers have the ambition of i) launching the product in the market in 24 months (at the end of the project) and ii) widening their business to geographical markets where, at the moment, they are not present, such as North and Central Europe. The SME-Instrument will be extremely important to help MTech and Vadac to expand their business to the gensets market. The SME-instrument funding will reduce the investment that the two companies have forecasted to carry out all the activities for the implementation, the validation and the demonstration of the prototype before launching the CHeaP generator on the market. The covering of 70% of investment by the SME-instrument funding will decrease the initial economic effort from ca € 752,500 to € 225,750 completely affordable by the two small companies

Keywords: camping van,seebeck effect,quasi zero noise
Airport System Protection from Intruding Drones (ASPRID)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Theme: Public-private partnerships
Destination: Single European Sky Air Traffic Management Research
Action type: Research and Innovation actions
Partnership: SESAR (Art-187)
Countries involved: Spain,Italy,Italy,Italy,France
Call: Innovation in Airport Operation (H2020-SESAR-2019-2, 2019)
Start date: 2020-11-01
End date: 2022-11-30
Duration (months): 25.0
Total project cost (EUR): 1235195.0
EU funding (EUR): 1235195.0
Participants: 7
Project status: CLOSED

ASPRID (Airport System Protection from Intruding Drones), is the response to the request made from SESAR under the Exploratory Research view, in order to cope with the problem of protecting the airport operations from drone intrusion (careless or malicious) under a holistic and operationally oriented approach. The Project proposes to investigate vulnerability of airport under the different types of threat and possible ways of response as well as to study the interrelations between all those aspects involving different scenarios. Risk analysis shall reveal and categorize the problem, from that, an architecture will be developed, dealing with the different steps and elements that can impact on operations, establishing adequate levels of alert, response and, if needed, neutralization. In this way, the stepped approach of the project will show these mainstreams: 1. Identification of problem: Threat(s), assets to protect (Airport, ATM, Aircraft), operations, 2. Setting scenarios: Risk and vulnerability assessment, hierarchization, selection, requirements. 3. Definition of an operational oriented architecture: a) At managerial level: Alert system and levels, Communications, Decisions, Response. b) At Specific technology elements: Detection, Identification, Tracking, Neutralization. 4. Concept Validation activities: HMI based solutions, sensitivity studies, integration of elements and subsystems in the airport environment. 5. Concept Support activities: Review and assessment of regulations and procedures (normal and emergency). ASPRID consortium members have experience with Airport and ATM operations as well as with drone performances and capabilities. A part of the consortium is also experienced in the development of SW and SW/HW based solutions to approach a system which is able to cope with the problem of decision making in real time by providing the end users with the correct level of awareness and response to deal with the type and level of threat.

Keywords: innovation in airport operation,protecting the airport from drones
StRategies fOr iMproving Agronomic practices based oN miCrobiomEs. (ROMANCE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-09-01
End date: 2022-08-31
Duration (months): 24.0
Total project cost (EUR): 160932.48
EU funding (EUR): 160932.48
Participants: 1
Project status: CLOSED

Plants live in association with a plethora of microorganisms, which constitute the plant microbiome. The management of this microbiome, boosting the presence of functionally relevant bacterial taxa, will improve the plant growth and development and enhance the yields of crops, which turns of paramount importance for feeding a constantly increasing World population. The selection of a determinate agronomic practice is also very important in order to maximize crop productivity. In this sense, intercropping and crop rotation are two agronomic practices that are quite common within the European Union and also, all over the world. The crops used in these cropping systems are normally one legume, such as pea or clover, and one cereal, such as barley or maize. The rationale of using a legume in those cropping systems is to provide the soils and the subsequent crop with a N source. There are numerous studies about individual crops´ microbiota as well as about bacterial isolates able to promote plant growth and performance. Moreover, there are studies stating that bacterial strains are able to protect the plant from biotic and abiotic stresses. However, there is a lack of studies on the interaction between the different members of a microbiome within each plant and the different microbiomes of the plants included in a given cropping system. The main aim of this action is to determine the core microbiome and their associated functions that are common between the crops in each cropping system. This knowledge will allow to design an adapted biofertilizer based on a simplified native community, which will improve crop fitness and productivity, as well as protect against quarantine pathogens. This final goal will turn itself as an effective tool for managing cropping systems such as crop rotation and intercropping from a microbiological vision.

Keywords: intercropping,crop rotation,mutualism,plant microbiota,omics
Research models in infection, cancer and regeneration: replacement and translation (REMODEL)

Framework: Horizon 2020 — Spreading excellence and widening participation
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Germany,Netherlands,Denmark,Portugal
Call: Twinning (H2020-WIDESPREAD-2018-03, 2018)
Start date: 2019-11-01
End date: 2023-04-30
Duration (months): 42.0
Total project cost (EUR): 799647.5
EU funding (EUR): 799647.5
Participants: 4
Project status: SIGNED

REMODEL combines the existing local expertise in bioengineering, cancer and infectious diseases with partners at the frontline in developing organoid systems, manipulating them to fit specific purposes and validating their use as models, in order to build capacity to work with innovative model systems that can replace animal experiments and increase translational relevance. In doing so, REMODEL addresses a key issue in today’s biomedical research: how non-animal model systems can be developed to meet the needs for translationally relevant research in the era of precision and personalized medicine, whilst at the same time accounting for societal pressure to replace animal experiments. REMODEL will capacitate the coordinating institution, IBMC-i3S, through the establishment of organoid advanced in vitro models and their customization for the main areas of research (infection, cancer and tissue regeneration). REMODEL will contribute to raising the research profile of the institution and scientific skills of its staff developed through training schools and short-term scientific training periods as well as transferable skills training and mentoring of Early Stage researchers, but also through staff participation in international conferences presenting work within the REMODEL themes / framework. Organoids as experimental models are at the frontline of methodological development in biomedicine, and demonstrating competence in working with such models will place i3S in the spotlight in an international research context, and make the institution an attractive partner for future collaborations beyond the REMODEL network. On the European level, REMODEL represents an important initiative to bring together key partners in the development of innovative models to overcome the present fragmentation of European organoid research and move towards applications in animal replacement.

Keywords: replacement,organoids,cancer,infection,tissue regeneration,translation,research model,experimental model,model system,validation
Bridging the gap between phytoremediation solutions on growing energy crops on contaminated lands and clean biofuel production (GOLD)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Alternative fuels and mobile energy sources
Action type: Research and Innovation actions
Countries involved: India,Germany,Italy,Italy,Italy,Greece,Poland,China,Greece,Greece,Greece,France,France,Netherlands,Netherlands,United Kingdom,Portugal,Canada
Call: Combined clean biofuel production and phytoremediation solutions from contaminated lands worldwide (H2020-LC-SC3-2020-RES-RIA, 2020)
Start date: 2021-05-01
End date: 2025-04-30
Duration (months): 48.0
Total project cost (EUR): 3710950.0
EU funding (EUR): 2999950.0
Participants: 21
Project status: SIGNED

GOLD is organized in five work packages (see figure aside) and builds on the three pillars. The first pillar (WP1) aims to optimize selected energy crops for phytoremediation as well as to develop optimized phytoremediation solutions for decontamination purposes. In the second pillar (WP2) the contaminated feedstock of WP1 will be converted to clean biofuels by developing two thermochemical based conversion routes; the first on gasification and the second on pyrolysis. In both routes the main contamination constituents will be collected in a concentrated form: mainly in a vitrified slag with low leachability produced in the gasification in the 1st and in a form of high density biochar in the 2nd. In the third pillar selected value-chains for biofuels production and land decontamination will be modelled and analysed in terms of cost, sustainability and SDGs for the creation of win-win situations. Emphasis is being given on the international collaboration towards Innovation Mission Challenge 4 on Biofuels with the participation of three highly consuming countries (Canada, China and India) thoughtout the value-chains.

Keywords: lignocellulosic energy crops,biofuels with low iluc risks,phytoremediation,decontamination projections,international collaboration,sgds