Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
AI-aided strategies for resource planning with predictive capabilities, generating up to 12 scenarios in seconds. Teams with thousands of multi-skilled and shared resources, maximising productivity. (AIRP)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 503842.5
EU funding (EUR): 503842.5
Participants: 1
Project status: SIGNED

AI-aided Resource Planner: AI-aided strategies for resource planning with predictive capabilities, generating up to 12 scenarios in seconds. ITER IDEA SRL is addressing the challenge of constantly changing workloads, resources and deadlines within work environments. Through the EIC Call, the team wants to bring the AIRP platform and the integration capabilities with existing systems to the service of European Manufacturing SMEs facing 35% higher Secondary Costs than the US and needing more support for human resources planning within their facilities. Today, with the improvements of Industry 4.0, manufacturers can communicate with machines and manage their scheduling. At the same time, the human resource and its characteristics are considered accessories or treated on inefficient supports to promote tolerable work conditions, inclusive planning and human-machine iteration. AIRP integrates with third-party solutions, MES (Manufacturing Execution System) and HR software and integrates any custom prediction models to improve accuracy and provides no-code configurators to map specific constraints and business objectives to fuel constraint programming models. When new tasks need to be allocated to operators or re-scheduled, the human planner can leverage AIRP to generate not one but multiple possible scenarios designed to solve the allocation of hundreds of multi-skilled shared resources, budgets, deadlines to meet, maximising productivity, balancing work pressure, pauses. A sustainable cloud infrastructure, leveraging cutting-edge Amazon Web Services technologies, enables AIRP to run What-if scenarios on the existing workforce and company data models. AIRP continuously highlights resource workload; planners can adjust or soften constraints and get new pressure maps in real time. AIRP supports the public sector in the UK and hospitals in Italy in allocating hundreds of resources with human-centric strategies.

Keywords: resource planning,business efficiency,manufacturing software,healthcare planning,workforce allocation,tolerable workplaces,previsional demand,scenario modelling,what if analysis
Tuberculosis Antimicrobial Stewardship Program (TASP): tackling Bedaquiline-resistant tuberculosis (TASP)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Public-private partnerships
Destination: Global Health EDCTP3
Action type: Research and Innovation actions
Partnership: EDCTP3 (JU-JTI)
Countries involved: Belgium,Nigeria,Netherlands,Sweden,Benin,Rwanda,South Africa,Canada,Mozambique
Call: Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials (HORIZON-JU-GH-EDCTP3-2024-01-two-stage, 2024)
Start date: 2025-06-01
End date: 2030-05-31
Duration (months): 60.0
Total project cost (EUR): 6299756.05
EU funding (EUR): 5999990.75
Participants: 12
Project status: SIGNED

In the 2024 updated Bacterial Priority Pathogen list of WHO, Mycobacterium tuberculosis (TB) is a critical priority pathogen, emphasizing the urgent need for action. Rifampicin resistant-tuberculosis (Rr-TB) is estimated to cause 13% of antimicrobial resistance-attributable deaths globally and is driven by both ongoing resistance acquisition and person-to-person transmission. Bedaquiline (BDQ), a new drug, is strongly recommended for Rr-TB treatment since 2018. In this very short time, BDQ resistance has proliferated significantly. For Rr-TB at risk of/with BDQ resistance (BDQr/Rr-TB) there is no evidence-based regimen. The current practice, with continued failing regimens, imperils the potency of the remaining Rr-TB drug arsenal. Tuberculosis Antimicrobial Stewardship Program (TASP) aims to rapidly reduce bacillary load in patients at risk/with BDQr/Rr-TB by using an empirical highly bactericidal intensive phase (for those at risk) followed by drug-susceptibility testing (DST)-informed artificial intelligence (AI)-aided Treatment Recommender's regimen composition. 125 participants at risk/with BDQr/Rr-TB will be enrolled in Nigeria, Mozambique and South Africa. Baseline and acquired resistance will be monitored and a novel, fast and quantitative phenotypic method (thin layer agar), with little infrastructural requirements, will be evaluated in TASP’s high burden, limited resource settings through decentralized implementation. Additionally, TASP will improve environmental control with co-designed, portable air cleaners, built sourcing low-cost materials from the local market. Filter waste products will be used for resistance surveillance and compared to conventional bio-aerosol samplers. The anticipated impact of TASP is a cost-effective TB antimicrobial stewardship programme that reduces further resistance development and salvages the current all-oral BDQ regimens for the future.

Keywords: bedaquiline resistance,antimicrobial stewardship dst informed treatment,thin layer agar,portable air cleaners
Smart management of energy and costs in museums. A chemical background for a control methodology for Temperature and Relative Humidity fluctuationss (SMARTMUS-E)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Czechia,Italy
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-08-01
End date: 2026-01-31
Duration (months): 30.0
Total project cost (EUR): 207848.4
EU funding (EUR): 207848.4
Participants: 3
Project status: SIGNED

Fellow: Paola Lucero; Host institution: Palacký University Olomouc (UPOL,CZ); Supervisor: Karel Lemr (Department of Analytical Chemistry, DAC-UPOL) Co-supervisor: Petr Bednar (DAC, UPOL); Host institution and Supervisor secondment: Ca’Foscari University (CFU, IT) Isadora Antoniano; Host institution and Supervisor non-Academic Placement: Gallerie dell’Accademia in Venice (GAV, IT), Silvia Salvini; Aim of the project: RO1: to give to the methodology that I published in 2020, for monitoring and control of fluctuations of temperature and relative humidity in museum environment, a chemical background considering materials degradation; RO2: to gain knowledge into materials degradation and determine what fluctuations can be tolerated by museum objects, without damage; RO3: To gain knowledge on historical buildings behavior and their capacity dumping outdoor weather variations RO4: to transfer the gained knowledge by training an initial set of end-users in cultural institutions to help them managing their energy consumption; Innovation: Creation of a methodology for characterization of museum indoor environment that considers material degradation. Enable conservation professionals to estimate how safe is museum environment in historical buildings under climate change influence. To contribute saving energy by allowing wider yet safe fluctuations of Temperature and Relative Humidity in museums with mechanical air conditioning systems; Procedure and data: Gain knowledge on materials behavior using analytical techniques to characterize degradation in mockup samples naturally and artificially aged and combine this data with the characterization of indoor environment in museums; Results: 2 Journal articles, 4 conference presentations, 7 workshops, 5 public events an online professional forum, online data repository for Temperature and Relative Humidity museum records Partner Institutions: GAV, Český Krumlov Castle, Viking Museum, Hist. Museum of Oslo, Nat. Heritage Institute CZ

Keywords: analytical chemistry,art materials,natural and artificial aging,energy saving,climate change
VALUE CO-CREATION AND SOCIAL INNOVATION FOR A NEW GENERATION OF EUROPEAN LIBRARIES (LibrarIN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Culture, creativity and inclusive society
Theme: Culture, creativity and inclusive society
Destination: Innovative Research on the European Cultural Heritage and the Cultural and Creative Industries
Action type: Research and Innovation actions
Countries involved: Greece,Belgium,Netherlands,Spain,Denmark,Germany,Finland,Austria,France
Call: New ways of participatory management and sustainable financing of museums and other cultural institutions (HORIZON-CL2-2021-HERITAGE-01, 2021)
Start date: 2022-11-01
End date: 2025-10-31
Duration (months): 36.0
Total project cost (EUR): 2992375.0
EU funding (EUR): 2992375.0
Participants: 10
Project status: SIGNED

LibrarIN is a research project that provides new avenues for participatory management and sustainable finance for European libraries, as key cultural institutions in their way to develop new functions, new services and new engagement with the individuals, organisations and the communities they serve. This requires social innovation based on public value co-creation and a demand-driven design of public library services that incorporate the opportunities provided by new technologies and new trends in service and user innovation to deliver outcomes serving a new generation of European public libraries. LibrarIN consists of i) an integrated conceptual framework to understand the process of value co-creation in public libraries service delivery, complemented with an evaluation of different approaches to knowledge transformation in public libraries, both in terms of their processes and their impact; ii) new metrics for public libraries transformation and new empirical case studies on existent and ongoing efforts to develop innovative public services in ways that enable the co-creation of value, including a novel European survey on innovation in public libraries; iii) Policy and managerial recommendations, and policy and managerial tools, to implement new ideas and scaling up best-practice experiences that effectively use value-co-creation to unlock social assets. The policy tools also include indicators for monitoring and evaluating existing initiatives to support public libraries service transformation. LibrarIN has a particular focus on three co-creation areas: digital transformation, living labs, and social entrepreneurship and public-private-third sector innovation networks.

Keywords: public libraries,social innovation,participation,value co creation,entrepreneurship,digitalisation,living labs
A fully implantable ventricular assist device for infants and small children (STAR BP)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Italy
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

STAR BP Italia is a biotech startup dedicated to addressing the unmet medical needs of infants and small children with heart failure (HF). The company's mission is to revolutionise the mechanical circulatory support (MCS) landscape with a novel, fully implantable paediatric ventricular assist device (VAD). Unlike existing solutions, it ensures superior biocompatibility, reducing the risk of infection and thrombosis. The device is specifically designed for the unique anatomical and physiological needs of paediatric patients, including infants and small children, who are underserved by current technologies. STAR BP’s miniature paediatric VAD will play a crucial role in enhancing the quality of life of paediatric patients awaiting organ transplantation by enabling a swift return to normal life and reducing hospitalisation periods. The reduced hospitalization periods facilitated by STAR BP's VAD can alleviate the financial burden on families, healthcare systems, and society at large. Altogether, this impact extends beyond medical benefits, encompassing social, humanitarian and financial dimensions. Founded by pioneers in the VAD industry, including senior executives, product development engineers, and internationally renowned cardiac surgeons, STAR BP is poised for ambitious growth. The company aims to bring its technology to a global market, ensuring that children and young adults worldwide benefit from these advancements. With the necessary funding to begin this EIC Accelerator project in 2025, conservative sales estimations project STAR BP capturing a 60% share of the global paediatric VAD market by 2033, translating to €86.5 million in total revenue from sales of 730 units.

Keywords: cardiac care,end stage heart failure,heart transplantation,mechanical circulatory support,paediatric ventricular assist device,fully implantable,hospital discharge
Infant nutrition, cognition, and health (INCH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,United Kingdom
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-01
End date: 2027-01-31
Duration (months): 24.0
Total project cost (EUR): 172750.08
EU funding (EUR): 172750.08
Participants: 2
Project status: SIGNED

The complementary feeding period, i.e. the time when infants are introduced to foods and liquids different from milk, has important implications for children's long-term social, physical, and cognitive development. While a large number of studies have surveyed the types of weaning foods provided, there is still a significant lack of research on the behavioural aspects involved in this important transition period. In terms of outcomes, existing studies have mostly focused on health effects, with very little attention paid to cognitive or language development. Lastly, most of the existing research is based on data from Western, industrialized countries, leaving us with a very incomplete picture of infant feeding practices and the resulting outcomes. Using a bottom-up approach, my project aims to fill these gaps by developing standardized tools for measuring infant feeding practices in rural and urban African settings, and investigating the impact of different feeding practices on children's health and developmental outcomes. Building on local contacts and relevant experience from a decade of research in Africa, I will (1) use focus group discussions to create a culture-sensitive questionnaire for measuring infant feeding practices; (2) use the questionnaire for a survey of infant feeding practices across rural and urban communities in Kenya; (3) collect detailed data on infants' nutrient intake; (4) assess children's motor, cognitive, and language development using tools which have been validated in similar African contexts, and correlate my data from 2, 3, and 4 to (5) identify feeding practices which relate to positive outcomes and can form the basis of future interventions.

Keywords: nutrition,feeding behaviours,cognitive development
Moduli Spaces of Sheaves: Geometry and Invariants (MoSSGIn)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 193643.28
EU funding (EUR): 193643.28
Participants: 1
Project status: SIGNED

In modern algebraic geometry, a key approach to studying algebraic varieties — and more broadly, orbifolds (quotients of varieties by finite groups) — is through their categories of sheaves. Sheaves are algebraic objects that encode crucial information about varieties and orbifolds, including their geometric subvarieties and solutions to equations defined on them. Packaging sheaves into moduli spaces allows a systematic way to study the structure and properties of the underlying orbifolds. This proposal focuses on moduli spaces of sheaves on three-dimensional complex orbifolds, which are of particular significance in theoretical physics, notably for capturing instanton dynamics in Calabi-Yau compactifications in type II string theory. Our main objective is to study the local geometry of these moduli spaces under pair-stability conditions and explicitly compute the associated Pandharipande-Thomas (PT) invariants, which are crucial for both enumerative geometry and string theory. The research is structured into three scientific work packages (WP): WP1 will introduce and study poset Quot schemes—a generalization of classical Quot schemes—which parametrize flags of quotient sheaves, nested according to finite posets. This tool will provide the foundation for further computations. WP2 will focuse on moduli spaces of stable pairs over local stacky curves, which are defined by rank 2 vector bundles over smooth projective curves with marked points and prescribed ramification indices. We will develop new methods to reduce the complexity of PT invariants computation to performing intersection theory on poset Quot schemes, making the problem more tractable and leading to explicit closed formulas for these invariants. WP3 will aim to prove the Gromov-Witten/PT correspondence for local stacky curves, a conjecture that has driven much of the research in enumerative geometry over the past two decades. Proving this correspondence would represent a major breakthrough in the field.

Keywords: moduli spaces,sheaves,curves,calabi yau,local curves,hilbert schemes,quot schemes,donaldson thomas,stable pairs,young diagrams,k theory,virtual fundamental class,derived geometry,tqft
Reproductive, Anthropometric and Disease traits Integrated: Coevolutionary Analysis of Life history trade-offs (RADICAL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Estonia
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-04-01
End date: 2025-08-31
Duration (months): 29.0
Total project cost (EUR): 167741.76
EU funding (EUR): 167741.76
Participants: 1
Project status: SIGNED

Life history theory (LHT) provides fundamental means to understanding adaptive evolution across the animal kingdom, including in our own lineage. Although observational studies have found plenty of support for the predictions of LHT in human populations, connecting traits such as birthweight and adult body size to age of menarche and menopause as well as disease risk, the fundamental biological mechanisms linking many of these traits are poorly understood. Here I propose, for the first time, to bring together matching genotype and phenotype data from two large national biobanks and state of the art statistical tools and genetic databases to formally investigate the extent to which the observational links between reproductive and anthropometric traits can be explained by pleiotropy and/or shared genetic pathways as well as the extent to which these pathways have been subject to natural selection over the past 10,000 years. The proposed interdisciplinary project, carried out at the Institute of Genomics, at University of Tartu (IGUT) will enable me to learn advanced techniques in association mapping as well as management of a project involving biobank and other clinical data under the supervision of experienced researchers at statistical and medical genomics. As such, the project provides an outstanding launchpad for the next stage in my research career at the intersection of evolutionary and medical genomics as an independent group leader.

Keywords: life history theory evolutionary trade offs reproductive and anthropometric traits regulatory networks ancient dna
Circular Construction Finance (CIRCOFIN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Other Bio-environnement destinations
Action type: Coordination and support actions
Countries involved: Germany,Portugal,Denmark,Ireland,United Kingdom
Call: Circular Cities and Regions Initiative’s project development assistance (CCRI-PDA) (HORIZON-CL6-2024-CIRCBIO-01, 2024)
Start date: 2025-01-01
End date: 2027-12-31
Duration (months): 36.0
Total project cost (EUR): 7020546.51
EU funding (EUR): 5999668.0
Participants: 14
Project status: SIGNED

The CIRCOFIN project brings together 4 cities and regions to transition to a circular economy in the construction and buildings sector. Munich, Copenhagen, Scotland and Lisbon will prepare investment-ready circular construction hubs (CCH) and showcase how they transform local and regional markets for secondary building components and materials. CCH cover physical material banks and digital infrastructure to provide the resource basis for the EU Taxonomy requirements for construction. To date, CCH have not successfully scaled-up across Europe. The project will demonstrate that CCHs can become bankable projects at scale and provide lucrative investment opportunities for financiers. The showcases develop sound technical, business, and financial plans of more than 80 M€ total investment volume. CIRCOFIN streamlines a common project development assistance (PDA) methodology for CCH, used and validated by the showcases. The methodology results in a CCH Toolbox, which consists of customizable components for all project development stages, from pre-feasibility to due diligence and bankability appraisal. It covers all elements of CCH – physical design, digital infrastructure, logistics, business models, operation models and financial models. The results will be published as a CCH Cookbook with concrete facts and figures, ready for widespread replication by other cities and regions. Replication and roll-out aim to trigger uptake in 30 other cities and regions from the CCRI, Circular Cities Declaration and the Mission Cities of the 100 Climate-neutral and Smart Cities Mission. Investors and EU financial initiatives will gain expertise in advising CCH projects via robust technical and operational insights and learn how to review associated risks, to make better investment decisions on circular economy projects. Standardization will on CEN and ISO as well as policy recommendations improve regulation to enable business and investment cases for CCH market uptake in Europe.

Keywords: circular construction,material bank,digital marketplace,circular markets,circular finance,ccri,circular cities regions initiative,circular construction hub,munich,scotland,copenhagen,lisbon