Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Agroforestry Business Model Innovation Network (AF4EU)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Coordination and support actions
Countries involved: Spain,Italy,Finland,Greece,Ireland,France,Belgium,Portugal,Slovakia,Germany
Call: Thematic networks to compile and share knowledge ready for practice (HORIZON-CL6-2022-GOVERNANCE-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 2996460.0
EU funding (EUR): 2996460.0
Participants: 17
Project status: SIGNED

The overall objective of AF4EU is to promote the European AF through the development of a multi-actor interactive and innovation-driven expanded agroforestry network. This will be based on the sharing of successful practical experiences and existing research knowledge (applied to different and new territories, climates and agricultural sectors) connected through ICT-Tools, with a special focus on the development and implementation of new cost-effective practices, business models and AF-extension services considering the whole food chain and therefore including consumers. All AF4EU partners have associated networks of AF farmers, policy makers and advisors thanks to their leadership of the European Agroforestry Association National Network and others are large farmers association itself (e.g. EFI) that will be an essential part of the 11 Regional Agroforestry Innovation Networks including relevant actors and specially operational groups. The Andalucian ministry of agriculture as policy maker is also part of the consortium. A set of 33 successful AF farm business models will be analysed across Europe from a sustainability perspective (economic, environmental and social). The project builds up on previous H2020 projects and aims at developing an AF knowledge platform that integrates a end-user (i) searchable knowledge reservoir namely Knowledge cloud, (ii) an alive-handbook, (iii) an agroforestry innovation business decision support tool (AFi-Bus DSS) including a business and a business environment analysis targeting AF policy in Europe and a Multilingual Massive Open Online Course (MOOC) with training modules targeting farmers and advisors. AF4EU will definitively contribute to the implementation and uptake across Europe thanks to the supply of cost-effective business models techniques and a successful communication, dissemination and exploitation planning reaching a large audience in Europe.

Keywords: regional agroforestry networks,multiactor,policy,business models,business environment,extension services,farmers,sustainable food systems
Imidazole propionate and fibrosis in cardiometabolic diseases (IMPACT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Sweden
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-08-01
End date: 2028-07-31
Duration (months): 60.0
Total project cost (EUR): 2482678.0
EU funding (EUR): 2482678.0
Participants: 1
Project status: SIGNED

Fibrosis is a pathological feature caused by excessive extracellular matrix secretion, resulting in scar tissue that causes thickening and loss of tissue mobility, culminating in impaired organ function. It is a common feature of heart failure and non-alcoholic steatohepatitis and an important determinant of morbidity and mortality. However, relatively little is known about the underlying aetiology. We and others have mapped alterations in the gut microbiota in different cardiometabolic diseases, focusing on the functions performed by the microbiota. IMPACT builds on our work showing that humans with type 2 diabetes have high plasma levels of the microbial metabolite imidazole propionate (ImP) and that ImP impairs insulin signalling through p38gamma. We also resolved the X-ray crystal structure of urocanate reductase (UrdA), the bacterial enzyme responsible for ImP production. Our recent work showed that ImP is more strongly associated with heart failure and that treatment of mice with ImP promotes both cardiac and liver fibrosis, consistent with studies showing that p38gamma signalling is implicated in fibrosis development. IMPACT will first use state-of-the-art clinical assessments to determine how circulating levels of ImP correlate with fibrosis in heart and liver. Second, we will explore the kinetics by which ImP induces fibrosis in mice and how this process is associated with immune cell infiltration and disease progression. Third, to provide mechanistic understanding, we will perform similar experiments in mice lacking key target signalling components (e.g., p38gamma), combined with single cell sequencing that will guide us in producing tissue-specific knockouts to elucidate the cellular cross-talk. Fourth, we will generate UrdA inhibitors and test their potential to reduce ImP production in isolated bacteria, complex microbial communities, and colonised mice. Thus, IMPACT has the potential of generating new therapies to diseases with unmet clinical needs.

Keywords: imidazole propionate p38gamma fibrosis heart failure nash
A European infrastructure for farmed animal genotype to phenotype research (EuroFAANG)

Framework: Horizon Europe — Excellent Science
Programme: Research infrastructures
Theme: Research infrastructures
Destination: Development and infrastructures
Action type: Research and Innovation actions
Countries involved: France,Netherlands,Germany,Norway,United Kingdom
Call: Research infrastructure concept development (HORIZON-INFRA-2022-DEV-01, 2022)
Start date: 2023-01-01
End date: 2025-12-31
Duration (months): 36.0
Total project cost (EUR): 2653314.25
EU funding (EUR): 2653314.0
Participants: 7
Project status: SIGNED

This proposal describes concept development and conceptualisation of a EuroFAANG (European Functional Annotation of ANimal Genomes) infrastructure to realise the full potential of genotype to phenotype (G2P) research across species, breeds and populations of farmed animal species in Europe. To achieve accurate G2P predictions, it is necessary to be able to refine and characterise highly complex traits as sets of intermediate informative phenotypes along the entire cascade from genome to cell, organism, environment, population and across different environments. The goal of the EuroFAANG infrastructure is to streamline use of interdisciplinary capabilities for G2P research in terrestrial and aquatic farmed animals and provide transnational access to all of the relevant facilities, expertise and knowledge to European stakeholders. This will address the need to bring together national facilities at the pan-European level in the field of animal genetic resources, phenotyping and breeding, and animal health, which was identified as a gap in the infrastructure landscape by the 2021 ESFRI Roadmap. The proposal builds on the foundation provided by the five current H2020 EuroFAANG projects, AQUA-FAANG, BovReg, GENE-SWitCH, GEroIMO and RUMIGEN and connects with existing infrastructures for data management and animal agriculture in the European research infrastructure landscape. The institutions and organisations involved have world-leading expertise in fundamental and applied farmed animal science and consolidated established connections to European stakeholders in farmed animal science. The outcomes of this proposal will lead to better alignment of the development of the research infrastructures landscape for the advancement of excellent farmed animal science and frontier G2P research in Europe and globally.

Keywords: faang,genotype,phenotype,animal breeding,farmed animals,genome editing,metadata,in vitro models,biobanking,data standards
Fluidity in the Medieval Aristotle. Readers and Readings of the Greek-Latin Translations (FitMA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: Belgium
Call: ERC STARTING GRANTS (ERC-2024-STG, 2024)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 1499655.0
EU funding (EUR): 1499655.0
Participants: 1
Project status: SIGNED

Aristotle’s impact on philosophy, science, and theology has been overwhelming, especially in the late medieval and early modern periods: hundreds of Aristotelian manuscripts survive to attest how strongly his works belong to the written culture of the pre-modern intellectual world. The understanding of Aristotle’s thought was decisively shaped by Latin translations from the 12th and 13th centuries. Translators’ efforts to preserve the exact phrasing of the texts and readers’ struggles to determine the disturbingly novel meaning lie hidden in modifications and notes in the manuscripts. These have however not received the attention they deserve, leading to a significant gap in our knowledge of the medieval reception of Aristotle. FitMA aims to fill this gap through a comprehensive investigation into the new ways to read the Latin Aristotle, with a ground-breaking focus on the textual variance in the handwritten books that preserve the translations. To realize that goal, FitMA will produce state-of-the-art critical editions of Greek-Latin translations of three of Aristotle’s most influential treatises on natural philosophy: De anima, De generatione et corruptione, and De caelo. Critical editions are the established scholarly means to document the variant readings in all manuscript witnesses of an ancient or medieval text. The study of that variance across versions or textual fluidity provides first-hand evidence how readers were exposed to the recently available translations, which are fundamentally different from their Greek originals. Because every manuscript copy of the Latin Aristotle generates a different state for its medieval reception, which cannot be adequately studied from the Greek text or a modern translation, FitMA will advance the state of the art by uncovering the importance of textual fluidity in the manuscripts of these translations and developing an innovative model of interpretation applicable to other medieval translations of philosophy and science.

Keywords: aristoteles latinus manuscript studies translation studies intellectual history aristotle
Ethical Design of Holography with Dense wireless Networks (HOLDEN)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Finland,Italy,Germany,Netherlands,Czechia
Call: EIC Pathfinder Open 2022 (HORIZON-EIC-2022-PATHFINDEROPEN-01, 2022)
Start date: 2023-06-01
End date: 2026-05-31
Duration (months): 36.0
Total project cost (EUR): 3020039.75
EU funding (EUR): 3020039.75
Participants: 7
Project status: SIGNED

Ubiquitous perception, by sensing of objects, subjects and gestures, is a pivotal challenge for future technology: it enables personalized services such as smart living, automated logistics or interaction through free-space gestures. However, it also challenges ethical and moral boundaries and threatens privacy. HOLDEN proposes a radically new approach to perception by concisely analysing ethical constraints and privacy risks while re-thinking RF-based sensing. We establish necessary conditions for privacy preserving and ethically compliant sensing and develop new paradigms respecting these constraints. For the first time ever, HOLDEN constitutes a concentrated effort to explore social aspects of RF-sensing to guide the technological advance and to derive technology for ethically and privacy compliant perception. Central to HOLDEN is the development of ethical and privacy constraints. We use these findings to derive privacy and ethically compliant concepts for RF-based perception. We will develop a system of distributed multi-antenna devices for simultaneous multi-target recognition and ubiquitous perception with unprecedented accuracy, which constitutes a radical paradigm shift from a technology-centric perspective to a privacy-centric one via privacy by design. HOLDEN achieves this goal along three high risk, complementary, and privacy-centric paths: Path 1: Continuous-space measurement points: Radio-based 3D vision by holographic image processing of RF wave-fronts. Path 2: Discrete-space measurement points: Advanced 3D beamforming for human-scale recognition and tracking through dense massive connected antenna arrays. Path 3: Signal processing and learning: High-dimensional tensor processing for the distinction of complex activities and motion from massive-dimensional RF data. The resulting breakthrough approaches and algorithms will be compared against application-level benchmarks via usage scenarios in the fields of logistics, smart living, and free-space

Keywords: ethics in ict,philosophy of technology,rf holography,radio vision,device free,ethical and privacy implications,responsible design,network sensing in massive mimo
East Africa's professionals in the making of our global information society (INFOSOC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Germany,Tanzania, United Republic of,United Kingdom
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-09-01
End date: 2025-08-31
Duration (months): 24.0
Total project cost (EUR): 173847.36
EU funding (EUR): 173847.36
Participants: 3
Project status: CLOSED

INFOSOC critically historicises our contemporary information society, demonstrating its global roots through original research into the lives of East African information professionals during a period of Cold War internationalisms (1950s-80s). To understand the persistence of information inequality, we need to place contestations over information in their socio-political contexts and historicise the social science disciplines that codified the meaning and power of information. This interdisciplinary project places information professionals (journalists, librarians, broadcasters, and government information officers) at its centre. How did trainers, trainees, and new professionals imagine and use what they called information and, crucially, with what consequences for our global information society? To answer this question, I will take my expertise in East Africa's global history into new interdisciplinary territory at a leading international institution for research on histories of mass communication, Freie Universitaet Berlin (FUB), under the supervision of an expert in the field, Dr Valeska Huber. Two substantial secondments in East African institutions, St Augustine University Tanzania (SAUT) and the British Institute in East Africa (BIEA), will enhance INFOSOC's innovative methodological basis and broaden its societal impact. Through a programme of training-through-research and a targeted communication and dissemination strategy, including a hybrid workshop organised in Berlin, the PF will allow me to pioneer a new sub-field of global information history and to demonstrate the pertinence of the East African case to academic audiences beyond African history, as well as to public audiences in Europe and East Africa. By the end of the PF, I will have established an independent research profile as a public-facing scholar with a research-driven teaching portfolio and a commitment to sustainable collaborations between European and East African institutions.

Keywords: history of social sciences east africa history of institutionalised knowledge information history internationalism cold war mass communication information science professions professionals
Local Addressing of Topological Interacting Systems (LATIS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental Constituents of Matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Belgium
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 1815546.0
EU funding (EUR): 1815546.0
Participants: 1
Project status: SIGNED

The LATIS project builds on the latest advances in addressing individual atoms and engineering topological band structures in optical lattices, in view of exploring the rich physics of interacting topological matter with unprecedented control. Ultracold topological matter has recently emerged as a central theme in the realm of quantum gases. By manipulating ultracold atoms in optical lattices, various experimental groups have realized a variety of topological band structures and detected their characteristic features. Creating topological matter with ultracold atoms offers a novel view on intriguing phenomena initially discovered in the solid state but also allows for the realization of exotic states that are inaccessible in real materials. This quantum-simulation approach to topological matter generates a constructive synergy between theoretical developments driven by curiosity and concrete technological applications. Until now, ultracold topological matter has been explored in the non-interacting regime of quantum gases, so that the observed quantities are associated with single-particle states. However, exciting avenues would become accessible upon combining engineered band structures with tunable interactions. This scenario would provide a concrete path towards the experimental realization of strongly-correlated topological states in ultracold gases. A promising path to create and address such states consists in manipulating a very small ensemble of atoms within a few lattice sites of an optical lattice, as now made possible by quantum gas microscopes. This setting would allow for unprecedented control over strongly-correlated topological matter, hence offering a unique framework for many-body quantum physics. The results emanating from the LATIS project will have a substantial impact on a wide scientific community working on quantum geometry and topological states of matter, with direct consequences for ongoing experiments on synthetic topological systems.

Keywords: quantum simulation,optical lattices,topological states of matter,artificial gauge fields
Virtual Embodied Reminiscence Therapy in Extended Reality (VERTEX)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Spain
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2023-POC, 2023)
Start date: 2024-01-01
End date: 2026-03-31
Duration (months): 27.0
Total project cost (EUR): 162857.14
EU funding (EUR): 150000.0
Participants: 2
Project status: SIGNED

VERTEX is a proof of concept project that aims to use virtual reality (VR) to improve the well-being of older adults. The project is based on the idea that psychological factors play a key role in age-related deterioration and that older adults' attitudes towards aging may be a significant predictor of physical and cognitive frailty. Participants will experience scenarios and events from their youth, such as being in a 1970s living room. They will be transported to memorable historical events from the time of their youth, such as famous concerts. The project aims to evaluate the effects of this experience on aging and provide evidence for the benefits of such an intervention, with the goal of supporting a spin-off. The project will involve several stages: a further implementation of the VR application continuing from results of an experimental study in the associated Advanced Grant MoTIVE, the carrying out of a further experimental study based on the new application, the rollout of the application to community centres providing opportunities for many people to experience this in such institutional settings, and the rollout to individuals to use in their homes on a loan basis. Focus groups with stake holders such as community centre managers will be carried out to assess the potential of the introduction of the VERTEX system as part of what can be offered to clientele. The business opportunity and regulatory framework will be investigated. All this information will be used to create a business plan that will make the case for investment to take the project forward in a spin-off to make VERTEX available on a large scale.
Generate simulation flowsheets (process flow diagrams, PFD) for the open-source chemical process simulator DWSIM (FlowsheetGenerator)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2490000.0
EU funding (EUR): 2490000.0
Participants: 1
Project status: SIGNED

The main directions for innovation in today’s chemical process industries are sustainability and process intensification. Integrated process design is the paradigm for designing efficient and sustainable processes. For example, the integration of several tasks in the same unit, as in reactive separations, simplifies the process design considerably and decreases both capital and operational costs. Modern steady-state and dynamic process simulation techniques allow the investigation of complex processes close to the real situation. DWSIM is an open-source software for both steady-state and dynamic process simulation and has modern object-oriented interfaces to connect with process control systems (PCS) and Asset Lifecycle Management systems, via e.g., Python, OPC UA and DEXPI. DWSIM includes features to calculate the greenhouse gas (GHG) emissions for a process according to the EU Emissions Trading System (EU ETS). The DWSIM Reporting feature provides important information to fulfill requirements of the Corporate Sustainability Reporting Directive (CSRD) and the EU Taxonomy Regulation. Simulate 365 Copilot generates and optimizes simulation flowsheets for DWSIM. For example, Copilot generated a solution space for the separation of a three-component mixture using ideal distillation with a result set of 1.620 flowsheets. Engineers save time creating and optimizing flowsheets, especially by avoiding trial-and-error. They receive converging flowsheets, i.e., the flowsheet fulfills first-order principles for further work. Today, Copilot creates separation sections for ideal distillation, pressure-swing distillation, extractive distillation and absorption processes for any DWSIM flowsheet and can be tested on www.simulate365.com With EIC support, we intend to add the remaining separation unit operations, e.g., membranes and other types of distillation columns to Copilot to be able to generate any separation section, and to add all other flowsheeting unit operations.

Keywords: process simulation,generative ai,chemical industry,flowsheet