Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Funds to make SJMethod project accessible for post-doc with physical disability (SJMethod)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: MSCA other
Action type: Coordination and support actions
Countries involved: Austria
Call: HORIZON-MSCA-SNLS-2021-IBA (HORIZON-MSCA-2021-SNLS-IBA, 2021)
Start date: 2021-08-01
End date: 2023-07-31
Duration (months): 24.0
Total project cost (EUR): 37062.5
EU funding (EUR): 37062.5
Participants: 1
Project status: CLOSED

The Marie Skłodowska-Curie actions pay particular attention to physical accessibility and inclusion and foresee financial support for the additional costs entailed by recruited or seconded researchers with disabilities.

Keywords: spinal cord injury,spinal avm,limited mobility,transportation,accessibility
Guided by a “sixth sense”: unravelling magnetic migration in Monarch butterflies (SixthSense)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Norway,United States
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2025-02-01
End date: 2027-01-31
Duration (months): 24.0
Total project cost (EUR): 210911.04
EU funding (EUR): 210911.04
Participants: 2
Project status: SIGNED

Each fall, millions of Monarch butterflies take off from to migrate over up to 5.000 km to their overwintering sites. During their long journey, they employ a wide range of cues to maintain their southerly flight direction. While monarch butterflies have been shown to be sensitive to magnetic information, its role during migration remains elusive. In this project, I will test the role of the Earth’s magnetic field during migration. Using a double-wrapped 3D-Helmoltz coil, I will study whether butterflies can use magnetic cues as a compass to keep their migratory direction (Magnetic Compass). In addition, by virtually displacing migratory Monarch butterflies, I will investigate whether they can also determine a specific goal location or even their own global position based on magnetic cues (Magnetic Map). I will next study the neural coding of magnetic information in the Monarch brain. I will target candidate compass neurons within the navigation network of the central complex using multichannel tetrode recordings. I specifically aim to obtain recordings from the head-direction neurons during magnetic field manipulation. I will test how the different magnetic field components are encoded in central complex neurons. In this way, I aim to obtain a detailed picture of the neuronal correlate for magnetic orientation. Besides compass or map, magnetic cues could also be used for compass calibration. While time compensation is a crucial aspect of a navigation, how it is established at a neuronal level remains elusive. I will investigate the role of the magnetic field as a geo-stable reference system for compass calibration. To do so, I will combine magnetic manipulations and a simulated sun stimulus to create cue-conflicts. I will use extracellular tetrode recordings in tethered navigating butterflies, to investigate the influence of cue-conflicts on the neural coding. I aim to unravel how magnetic and celestial cues are integrated to create a time-compensated sun compass.

Keywords: magnetic sense,compass or map orientation,time compensation,compass calibration,central complex
Novel unified and extended mixture theories: theory and numerics (OMNIA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Mathematics
Countries involved: France,Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-01-01
End date: 2027-12-31
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 3
Project status: SIGNED

OMNIA proposes a unique combination of mathematical physics and numerical analysis to achieve new, provably structure-preserving discretizations of novel unified and extended mixture theories. This project is based on the firm belief that to obtain reliable numerical results, especially in a complex field such as mixture theories, where exact solutions are lacking, a deep understanding of the basic mathematical modelling framework is required. So far, there is no mixture theory capable of describing the processes occurring in a multiphase flow in a closed and comprehensive manner, respecting the laws of thermodynamics and the principle of causality. For this reason, OMNIA, after adequately addressing numerically what is most exhaustive in the literature, aims to establish a theoretical framework to extend the existing model to derive a non-equilibrium mixture theory which simultaneously includes fundamental processes such as convective and dissipative effects but also dispersive processes. Finally, to address the resulting complex monolithic model, finite volume methods with novel structure preserving properties will be developed, that not only accurately solve the obtained system respecting its thermodynamic properties at a discrete level, but also preserve additional mathematical characteristics. Namely, new semi-implicit, asymptotic-preserving numerical methods will be devised which are capable of preserving the curl free constraints endowed by the model.

Keywords: compressible multiphase flows,symmetric hyperbolic and thermodynamically compatible shtc theory,hyperbolic thermodynamically compatible htc schemes,structure preserving,asymptotic preserving
Fiction, Literature, Indigenous Storytelling and History (FLORISH)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 187624.32
EU funding (EUR): 187624.32
Participants: 1
Project status: SIGNED

This project explores the unique potential of historical fiction as a transformative method to create counter-representations of Indigenous peoples in Brazil, where they are often seen as inferior and savage because of their close connection to nature. These stereotypes, spread by European colonisers through literature and historiography, have become ingrained in collective sensibilities and are currently used to justify racism against Indigenous peoples, the illegal occupation of their lands and the deforestation of the Amazon rainforest. Historiography has criticised these views, but due to its dominant epistemology, which relies firmly on written records, the field does not usually go beyond deconstructive ambitions. Indigenous ethnic groups, on the other hand, tend to pass on their histories orally, so their ecocultures and resistance to colonialism fall outside the lens of prevalent epistemology. The central research question of this project is: How can historical fiction help us explore pluralistic views of the Indigenous pasts and open up new visions for a sustainable and diverse future? Answering this question calls for innovative and interdisciplinary methods to achieve three goals: (1) to understand how Brazilian writers have used historiography and fiction to represent Indigenous peoples in historical novels; (2) to identify how the epistemology of historiography constrains (or even silences) the writing of Indigenous historical fiction; (3) to develop a method of collective writing with Indigenous authors that allows us to co-create representations of their pasts and ecocultures. The project draws on Decolonial Studies, Theory of History and Literary Theory, and combines methods of discourse and intertextual analysis, qualitative interviews and collaborative writing with Indigenous writers from Brazil. The proposal moves from deconstruction to reconstruction in a context of growing appeal for a sustainable, multicultural and decolonised world.

Keywords: indigenous peoples historical fiction decolonial methods ecology brazil
Advanced Reduced order modellinG: Online computational web server for complex parametric Systems (ARGOS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Italy
Call: ERC PROOF OF CONCEPT GRANTS1 (ERC-2022-POC1, 2022)
Start date: 2022-07-01
End date: 2023-12-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

The Proof of Concept “Advanced Reduced order modellinG: Online computational web server for complex parametric Systems” ARGOS wants to fulfil the demand of a Reduced Order Modelling Offline-Online tool, exploitable thanks to the creation of a computational interface, handling and analysing a parametric problem in a very intuitive way. ARGOS is a computational web server hosting several web applications, some with a general purpose and some for very specific problems: users can access directly through the web browser, using their available device, choose the application they need and finally use it to tackle the problem of interest. Thanks to the web application, users do not have to install any package by themselves on their machine. Any device having an internet connection can access ARGOS and run a web computing application. The real time response, due to the model reduction algorithms, combined with the ease of use of ARGOS, matches the industrial demand of intuitive and immediate tools. Within this black-box framework, the final user is not required to have any specific and technical knowledge about reduced order modelling. We thus envision that this approach could be adopted also in many other fields directly related with applied sciences, for example in medicine and environmental studies. ARGOS will have a vast audience of companies and institutions, proposing a closer integration between design teams and research and development teams. ARGOS could also be easily connected with emerging technologies related with data assimilation, data science and analytics, industrial digital twins, machine learning, diagnosis and maintenance tools, etc. The mathematical core of the web platform ARGOS will rely on the software developed within the ERC CoG AROMA-CFD project by valorising open source software libraries ITHACA and RBniCS. Different demos will be developed, for example in bioengineering, structural mechanics, and industrial shape optimisation in fluid dynamics.
Bridges in social networks: Harnessing dual identity to improve interethnic relations (DUALNETS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: The Soci al World and Its Interactions
Panel description: Sociology, social psychology, education  sciences , communication  studies
Countries involved: Netherlands
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-09-01
End date: 2027-08-31
Duration (months): 60.0
Total project cost (EUR): 1999894.0
EU funding (EUR): 1999894.0
Participants: 1
Project status: SIGNED

Improving relations between ethnic minority and majority groups is one of the most pressing needs in modern societies. This project will test a new theory: that such relations can be improved by minority members who identify with both their ethnic group and the national majority group, because these dual identifiers can create social bridges between communities. However, not all dual identifiers are recognized as such by others, and misperception may undermine the bridging that dual identifiers can accomplish. I propose that (a) dual identifiers’ relationships with members of both groups are signals of their dual belonging, but that the degree to which these signals are picked up depends on people’s perception of the structure of their social networks, (b) that perceiving dual identifiers improves intergroup attitudes and relationships, and (c) that these effects occur most likely under specific situational and social psychological conditions. Thus, this project will advance the interdisciplinary fields of intergroup relations and network science by moving away from the problematic assumptions of previous work that people are always fully aware of others’ dual identities and relationships. I will develop and test a pioneering methodology to measure perceptions of people’s ethnicity and their relationships in social networks. Survey experiments and a two- and three-wave longitudinal school study will then be conducted to (1) detect how perceived relationships in social networks affect recognition of dual identifiers, (2) uncover whether and how perceiving dual identifiers (as social bridges) improves interethnic relations, and (3) discover factors that prevent or facilitate the effect of dual identifiers. Next to the theoretical innovation, the focus on the consequences of perceived social networks will break new ground in social network analysis. The findings will lead to new approaches for facilitating the development of positive interethnic relations.

Keywords: social network analysis,intergroup contact,ethnic identity,longitudinal,methodology
Supporting the potentials of digital, data-driven solutions for livestock tracking (Digi4Live)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Innovative governance, environmental observations and digital solutions in support of the Green Deal
Action type: Coordination and support actions
Countries involved: Finland,Netherlands,Greece,Serbia,France,Belgium,Germany,Poland,Denmark
Call: Digital and data technologies for livestock tracking (HORIZON-CL6-2023-GOVERNANCE-01, 2023)
Start date: 2024-01-01
End date: 2028-06-30
Duration (months): 54.0
Total project cost (EUR): 5004646.19
EU funding (EUR): 4995979.19
Participants: 16
Project status: SIGNED

EU Data Governance Act and recent advances in technology provide a unique momentum to automate and expand livestock data collection, integration and exploitation by strengthening the coordination of efforts of science and industry. The ultimate goal of Digi4Live is to increase the capacity of livestock sector actors across Europe to benefit from data generating and digital technologies. By using a strong multi-actor and co-creation approach, which brings together livestock sector actors from farm to fork, from science to livestock and technology industries, competent authorities, and other key actors, and engages them in co-creation of digital & data concepts, Digi4Live enables greater use of current and new data & digital technologies in livestock tracking. Digi4Live is a 4.5 years coordination and support action that is reaching out to over 1000 organisations and initiatives across Europe to make an impact towards economically, environmentally and socially sustainable, digitalised livestock business that meets consumers’ expectations, more effective public administration and impactful policy. Digi4Live boosts the creation of standards and harmonised regulations, thus eliminating technical barriers for data and new data-generating technologies, and provides evidence on economic, social and environmental impacts of data-driven solutions in the livestock sector and boosts collaboration between R&I initiatives across all EU member states and beyond. It will point out how public administration and policy monitoring & assessment, businesses and consumers can benefit from digital technologies. Concepts for greater exploitation of data will be co-developed and examined in six thematic case study hubs and brought to the attention of end users to. Such an integrated approach can really make a difference by enabling substantially improved use of data for the benefit of science, policy and business. The project will provide policy and business conclusions.

Keywords: standardisartion,sensors,artificial intelligence,co creation,technology evaluation,sustainability,design thinking,
Challenging the fundamental limit of angular dispersion by hybridizing light and matter (HyAngle)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Systems and Communication Engineering
Panel description: Electrical, electronic, communication, optical and systems engineering
Countries involved: Germany
Call: ERC ADVANCED GRANTS (ERC-2022-ADG, 2022)
Start date: 2023-12-01
End date: 2028-11-30
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Interference is one of the most fundamental phenomena in optics, allowing us to confine, filter, manipulate and steer light with exquisite precision. It is at the core of thin-film optics and nanophotonics, two areas of science that catalyse major scientific and industrial advances. One fundamental property of optical interference, however, constitutes a major limitation – the characteristics of any interference-based structure depend on the angle between the light wave and the structure itself (e.g. the transmission wavelength of optical interference filters shifts strongly when the angle of incidence changes). So far, this ‘angular dispersion’ effect remains a largely unchallenged fundamental limit in optics. HyAngle now proposes a novel strategy based on hybridizing light and matter states to break the angular dispersion limit. By tuning the coupling strength and offset between a photonic resonance formed by optical interference and the electronic resonance causing optical absorption in a material, I expect to be able to realize interference-based optical devices with spectrally sharp and angle-independent transmission, reflection and emission. We will explore the physics, potential and limitations of this approach by developing and studying dispersion-free optical filters, colour converters and LEDs with narrowband spectra. We will then pursue two specific applications, namely hyperspectral cameras and bio-implantable lensless fluorescence microscopes, where our devices will enable major advances in capability and unprecedented performance in deep tissue applications. Our devices use organic materials that can be readily processed by high-throughput vacuum deposition and even from solution. The amorphous nature of these materials renders them intrinsically compatible with the dielectric and metallic films widely used in the optics and display industry. The strategy of HyAngle thus bears great potential for rapid development and broad application.

Keywords: thin film optics,organic electronics,strong light matter coupling,optoelectronics,optical filters,biophotonics,bioimplants,biomedical optics
Endothelial immunosuppressive mystery genes for alternative immunotherapy: artificial intelligence-driven target discovery and lipid nanoparticle/RNA-based target validation (MystIMEC)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology  of ageing , pathophysiology, inter - organ and tissue communication, endocrinology, nutrition,  metabolism, interaction with the microbiome, non -communicable diseases including cancer (and except disorders of the nervous system  and immunity -related diseases)
Countries involved: Belgium
Call: ERC ADVANCED GRANTS (ERC-2021-ADG, 2021)
Start date: 2023-03-01
End date: 2028-02-29
Duration (months): 60.0
Total project cost (EUR): 3498426.0
EU funding (EUR): 3498426.0
Participants: 1
Project status: SIGNED

Compared to my previous Advanced ERC grants, this proposal is fundamentally different not only concerning its topic but also regarding its ambition to offer greater societal impact by coupling knowledge gain tighter to translation. It promises to obtain new insights in an understudied endothelial cell (EC) subtype with immunomodulatory gene signatures (coined “IMECs”), highly relevant for alternative immunotherapy development. Indeed, silencing immunosuppressive genes in IMECs offers unprece-dented opportunities to improve the efficacy of and to overcome the resistance to current anti-cancer immunotherapy, to which the immunosuppressive tumor endothelium contributes. To identify previously unknown/unmined (“virgin”) drug targets, we also focus on “mystery” genes, lacking func-tional annotation / PubMed reports (comprising 30% of the human coding genome). We developed: (i) an innovative artificial intelligence (AI)-based tool (SCMYSTERYDENTIFIER) to predict new immunosuppres-sive functions for endothelial “mystery” genes; and (ii) a revolutionizing (“REVOLT”) technology (based on injecting EC-selective lipid nanoparticles containing sgRNA in mice expressing Cas9 selectively in ECs) to generate EC-specific knockout mice rapidly (days)/inexpensively (300€/mouse) at an unprece-dented scale in order to validate these targets. Demystifying the mystery genome offers formidable opportunities for knowledge gain and therapy development. We will validate 50 new EC targets and aspire to identify and patent 5 previously unknown targets for alternative IMEC-based immunotherapy. The SCMYSTERYDENTIFIER tool can be made generic to discover any type of function for mystery genes in any cell type, while the REVOLT technology promises to revolutionize the pace of genetic research in the vascular biology field, offering formidable impact for the research community in academia and pharma.

Keywords: endothelial cells,immunotherapy,single cell omics,gene editing,target discovery,target validation