Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
On-demand production platform enabling perfect fitting bespoke apparel for textile SMEs and retail chains reducing return rates by 50% and overproduction by 90% (4D4Fashion)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Germany
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2134125.0
EU funding (EUR): 2134125.0
Participants: 1
Project status: SIGNED

Textile production suffers from unsustainable supply chains, outdated size tables resulting in ill-fitting clothes, high return rates, and overproduction. The value creation takes place in the Far East. Tailor-made textiles are only available in the premium price segment because measurement of body dimensions is done manually and developing a customised sewing pattern is complex. OpenDress developed a software solution for the on-demand fabrication of individually fitting clothing enabled by an interactive design tool for creating custom-fit textiles based on 3D/4D body scans via a smartphone in the domestic environment. Core features of the software are the patented pattern development method and algorithms for individualised clothing production, the digital twin, and an app for 3D/4D avatar creation. The solution for size determination and the creation of sewing patterns is seamlessly integrated by SME and retail chains in web shops identifying the perfect size for end customers.

Keywords: fashion industry,e commerce,textiles,apparel,4d body scan,virtual try on,gamification,user experience,api,size recommendation,plug and play,mass production,storag,micro factories,avatar
method for smart and affordaBle Evaluation of simultaneous faults in heating and cooling sYstems based ON compresseD vapor technology (BEYOND)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Challenges
Action type: EIC actions
Countries involved: Italy,Spain
Call: EIC Pathfinder Challenge: Clean and efficient cooling (HORIZON-EIC-2023-PATHFINDERCHALLENGES-01, 2023)
Start date: 2024-09-01
End date: 2028-08-31
Duration (months): 48.0
Total project cost (EUR): 1181750.0
EU funding (EUR): 1181750.0
Participants: 2
Project status: SIGNED

This project seeks to revolutionise fault detection, diagnosis, and evaluation (FDDE) by designing an innovative, knowledge-based and cost-effective method. Currently, FDDE for VCCS is performed only for large plants. For small plants, instead, only FDD is run, while the Evaluation is not affordable, according to current patents, allowing eventually only one fault per time. The innovation beyond the SoA of our proposal lies in the method's ability not only to detect but also to precisely identify their types and to assess the severity of up to three concurrent SOFT-faults (complete FDDE), in terms of refrigerant charge and heat exchangers fouling, which are the most insidious among the frequent ones. Through data processing the method allows to collect energetic and environmental knowledge of the system, and to elaborate economic calculations, making possible to provide a powerful and innovative decision-support service of interest for: energy service providers, final users or policy makers. Beyond the project, the method could be easily implemented in small-size vapor compression systems (VCCS, the most common kind of system) preserving the original hardware except for some cheap extra measurements and data processing, that can be easily done and managed with IOT devices and ICT infrastructures. The research proposed will investigate a method through the proof of concept about the possibility to determine univocally the FDDE running an appropriate set of values to the degrees of freedom of the machine. The research requires the development and experimental validation of a model; the production of a huge synthetic database for several machines; the demonstration of the method by a virtual test and the effective experimental validation. The project is relevant to the Challenge scope, aligning with the objectives of exploring new methods and processes to reduce operational costs, increase efficiency, and enhance environmental performance in cooling systems.

Keywords: heat pumps advanced strategies predictive maintenance high systems resilience fault tolerance process efficiency environmental performance
Improving water management in semi-arid regions: Insights in hydrological and environmental controls of lakes using triple oxygen isotopes (HydrO-17)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Spain
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2022-10-01
End date: 2024-09-30
Duration (months): 24.0
Total project cost (EUR): 165312.96
EU funding (EUR): 165312.96
Participants: 1
Project status: CLOSED

Lakes provide an important water resource for agricultural and industrial purposes, and form a critical habitat for plants and animals. Understanding the hydrological functioning of lakes is fundamental to understand hydrological feedbacks related to changing environmental conditions in the context of current climate change and also of increasing importance for environmental policy. Stable isotope ratios of water (2H/1H, 18O/16O) are widely used in lake hydrology studies, providing information on the hydrological balance of lake systems. However, in cases where the system is under-defined, a full quantitative assessment of the lake’s hydrological balance is challenging. Recent investigations have demonstrated that the additional analysis of the rare oxygen-17 isotope can provide additional quantitative information about the hydrological and environmental conditions during lake evaporation. The HydrO-17 Project will explore the potential of the triple oxygen isotope analysis (18O, 17O, 16O), expressed as 17O-excess, for quantitative hydrological balancing of lakes by examining the seasonal isotope evolution of hydrologically different lake systems in the Andalusian lowlands, Southern Spain, where agricultural overexploitation of groundwater aquifers over the last decades led to a severe water deficit. Current climate change will further intensify these problems. The results of the project will contribute to the understanding of the hydrological functioning of lake systems in Andalusia, with implications for local water management strategies. The approach has potential application to lakes in other regions in the world. The outcomes will also help to improve the interpretation of paleoclimate and paleoenvironmental information obtained from paleo-lake sediment archives.

Keywords: stable isotope geochemistry,triple oxygen isotopes,lake systems,evaporation
Scalable systems modelling to simulate body-level interplays among non-communicable diseases (O-Health)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Products and Processes Engineering
Panel description: Product and process design, chemical, civil, environmental, mechanical, vehicle engineering, energy processes and relevant computational methods
Countries involved: Spain
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2022-11-01
End date: 2027-10-31
Duration (months): 60.0
Total project cost (EUR): 1998865.0
EU funding (EUR): 1998865.0
Participants: 1
Project status: SIGNED

Non-communicable diseases (NCD) that involve load-bearing organs emerge silently according to complex mechanisms that are likely to involve inter-disease systemic communications. Clinical explorations cannot apprehend such intricate emergence, but I postulate that multiscale in silico models can. The digital twin for health has progressed a lot in the last decades, but multi-disease transversal modelling has not happened. It requires unique developments to couple small to large-scale model components with appropriate balance of phenomenological and mechanistic approaches, to cope with overwhelming biological complexity, preserve interpretability and incorporate real-world data. This is the niche of O-Health that proposes a scalable ecosystem of multiscale NCD models interrelated through a systemic model of low-grade inflammation. The project tackles such vertical and transversal physiology-based computational modelling through four major NCD, lung emphysema, atherosclerosis, intervertebral disc degeneration and knee osteoarthritis that affect load-bearing organs at different anatomical locations. The cellular /molecular scale components of each NCD model will vertically share predicted variables with an interface model of endothelial cell dysfunction that communicates with a transversal model of body-wide systemic communications. The O-health ecosystem will be modular and interoperable. Mechanistic modelling will be covered by finite element models at the organ /tissue scales and by agent-based (AB) models at the cell /molecular scales. AB models will incorporate high-level interaction graphs for interpretable phenomenological modelling where necessary. Graphs will merge knowledge projection and correlation models extracted from longitudinal population cohort data, also used to evaluate O-Health. Interoperability will be ensured through standard languages such as Field and Systems Biology Mark-up Languages, enabling the scalability of the O-Health ecosystem.

Keywords: computational biomedical engineering systems mechanobiology systems biology finite element modelling agent based modelling multi scale modelling digital twin for health physiology based computational modelling
A social normative model of solidarity-based collective action: Mobilising support for indigenous rights through social media (MobiliseSolidarity)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Ireland,Chile
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2024-03-15
End date: 2027-03-14
Duration (months): 36.0
Total project cost (EUR): 238581.6
EU funding (EUR): 238581.6
Participants: 2
Project status: SIGNED

Indigenous rights groups have become increasingly active worldwide. Mobilising support for indigenous rights movements aligns with a key UN Sustainable Development goal, (10) Reduced Inequalities. This fellowship aims to elucidate how support for indigenous rights movements can be mobilised among the public by capitalising on the influences of social norms and the ease at which they are spread through social media platforms. Though social media can be a tool for mobilisation, little is known about the psychological impacts of perceiving messages of solidarity online. In this fellowship, I will expand my expertise on social norms by examining whether and how these normative messages influence advantaged groups’ engagement in indigenous rights movements, and how these messages impact the indigenous groups themselves. I will employ innovative experimental and longitudinal methods to illuminate how different normative messages facilitate different psychological motivations for solidarity-based collective action. I will draw on my current expertise in attitude networks to examine the issue from a novel perspective, and transfer these skills to my TC Host. I will gain skills in social media analysis and longitudinal data analysis, which are vital for the research programme, and which I will transfer to my EU host. The impact of this research will be enhanced by utilising a multigroup and multicontext approach, comparing findings from advantaged groups and disadvantaged indigenous groups across Chile and Ireland. This fellowship will expand the psychology of social movements by presenting a novel normative approach to solidarity. Findings will assist Mapuche and Mincéir rights organisations in Chile and Ireland respectively in understanding how framing of social media campaigns can better mobilise public support. Knowledge gained through this fellowship will be pivotal for the growth of my career as a leading researcher addressing injustices facing minorities in society.

Keywords: political psychology collective action social identification,social norms perceived injustice group efficacy indigenous rights
Potential Effects of Harmful Algal Blooms on Bivalve Reproductive Output (PERIL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France,Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-04-01
End date: 2028-03-31
Duration (months): 24.0
Total project cost (EUR): 226420.56
EU funding (EUR): 226420.56
Participants: 3
Project status: SIGNED

Harmful algal blooms (HABs) pose significant threats to marine ecosystems, human health, and coastal economies worldwide. These blooms often coincide with the breeding periods of bivalves, adversely affecting their reproductive output. Bivalve aquaculture, which is crucial for food security and coastal economies, is particularly vulnerable to these effects, threatening the sustainable production of cultivated bivalve species. Despite extensive research on HAB-related toxins and their implications for food safety, the broader physiological effects on bivalve reproductive health remain poorly understood. With HABs increasing in frequency due to global changes, investigating their impacts on bivalve reproduction is essential for addressing the resulting ecological and socioeconomic challenges. The PERIL project aims to assess the impact of regularly blooming and emerging HAB species in European waters on the reproduction and early developmental stages of commercially and ecologically important bivalves. Specifically, the project will elucidate the toxicity of HABs on bivalve gametes through both direct and parental exposure. The mechanisms affected by HAB exposure during bivalve gametogenesis, embryo-larval development, and the parental transmission of traits to offspring will be thoroughly investigated. To achieve these objectives, a novel integrative approach will be employed, encompassing physiological, cellular, molecular, and epigenetic analyses. Overall, PERIL represents a pivotal step toward a comprehensive understanding of HAB phenomena on bivalve population renewal. It will generate data to support the development of a standardized bioassay, which will serve as an innovative tool for assessing the reproductive toxicity of HABs. This approach has the potential to revolutionize strategies for bivalve conservation, restoration, and aquaculture.

Keywords: bivalve reproduction,gametes,harmful algal blooms,parental effects,toxicity mechanisms,transgenerational plasticity
Targeted delivery of lipid nanoparticle-mRNA formulations modified with ligand pattern to dendritic cells based on DNA origami (LIPIRNADO)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-08-01
End date: 2025-07-31
Duration (months): 24.0
Total project cost (EUR): 222727.68
EU funding (EUR): 222727.68
Participants: 1
Project status: CLOSED

mRNA vaccines have gained considerable attentions in prevention and treatment of virus infections, cancer and genetic diseases, especially in the application to the COVID-19 pandemic in recent years. Due to the immunogenicity and instability of mRNA, the in vivo delivery of mRNA plays a crucial role in vaccine efficacy. Among various materials, lipid nanoparticles (LNPs) have shown to be one of the most potent carriers for mRNA delivery and successfully enter the clinic. To further improve vaccine efficacy, dendritic cells (DC) uptake can be optimized by decorating mannose ligands on LNP-mRNA formulations for targeted vaccine delivery. However, the effect of ligand density, spatial distance and organization pattern on cellular uptake remains poorly understood. Due to the addressability of DNA origami, nanoparticles and small molecules can be spatially organized into prescribed pattern with nanoscale precision. Therefore, we propose to develop designed ligand patten on LNP-mRNA formulations by transferring ligand pattern distributed on DNA origami to LNPs. With ligands modified on surface, LNP-mRNA formulations will be used to investigate the effect of ligand pattern on DC uptake, which is not accessible to other targeted delivery system. The results of the project will promote the development of vaccine delivery field. In addition, it will influence the health care and biomaterial industries, which are central to Europe’s ongoing and future economic success.

Keywords: dna origami,lipid nanoparticle,mrna vaccine,drug delivery
Dendritic Activity and Neuromodulators in Active Learning (DANAL)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-05-01
End date: 2026-04-30
Duration (months): 24.0
Total project cost (EUR): 211754.88
EU funding (EUR): 211754.88
Participants: 1
Project status: SIGNED

Neuroscience research tries to tease apart how brain circuits work together to give rise to behaviour, namely cognitive flexible processes, such as reinforcement learning (RL). RL requires neurons to be tuned to relevant inputs in order to maximize behavioural performance. Most of the excitatory synaptic inputs in pyramidal neurons are located in the thin dendrites where the majority of the spines are located. Thus, thin dendrites play a crucial role in synaptic integration and experience-dependent plasticity. They mediate local computations that endow single neurons with a variety of input–output transformations and change their information transfer. In agreement, individual dendrites have been proposed as the fundamental computational unit of neurons and the substrate for increasing the computational power of the brain. On the other hand, the neuromodulatory systems are known to be critical regulators of brain states and of adaptive responses relevant to RL. Different neuromodulators, acting through their receptors, can alter intrinsic properties of dendritic ion channels and receptors and synaptic efficacy, having a direct impact on dendritic computations. Thus, in order to understand how the brain allows to quickly improve behavioural performance during RL, it is critical that we 1) gain insight about the activity on thin dendrites, 2) to systematically understand the activity of different neuromodulatory inputs on those and 3) their impact on RL. This proposal aims at identifying how neurons change their properties during RL, by observing and manipulating the neurophysiology of behaving mice, using interdisciplinary approaches and state-of-the-art methods. The work will address several original questions: 1) what is the role of tuft dendritic activity to implement an adequate RL?; 2) what is the role of different neuromodulators in shaping the tuft dendritic activity and on RL?

Keywords: dendritic activity,in vivo imaging,neuromodulators,reinforcement learning
Scattering Ampltidues for Multi-hadrons Processes in Lattice-QCD (SAMPL-QCD)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Switzerland
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 292118.88
EU funding (EUR): 292118.88
Participants: 1
Project status: SIGNED

The goal of SAMPL-QCD (Scattering Amplitudes for Multi-hadrons Processes in Lattice-QCD) is to compute, with a novel method, exclusive scattering amplitudes involving multiple hadrons in the final state, such as J to ππ or J to πππ, with J=B,D,e+e-,...from Euclidean correlation functions computed in lattice QCD. The motivation is to provide new theoretical predictions to compare with experimental data that already exists, and that will keep being produced, with the ultimate goal of finding evidence for physics beyond the Standard Model. The state-of-the-art for theory predictions of multi-hadron processes is the K→ ππ study from the RBC/UKQCD collaboration. The methodology employed there is based on the Lellouch Lüscher formalism, which appears hard to generalise to processes where many inelastic thresholds can open simultaneously. A different strategy that does not suffer the same complications is now possible, because of two factors: on one side, a mathematically-robust relation between Euclidean correlators (available from lattice QCD) and scattering amplitudes was given by A. Patella & N. Tantalo in terms of an inverse problem. On the technical side, progress made by my collaborators and I in the last few years in solving the inverse problem with reliable estimates of its systematics, paves the way for first QCD calculations of this kind, potentially opening the way to a new generation of lattice calculations. In this project, we intend to explore the level of precision that can be reached, within this formalism, for scattering amplitudes, given the current state-of-the-art lattice simulations.

Keywords: lattice qcd,lattice simulations,scattering amplitudes,s matrix,precision physics,hadronic physics,hadronic decays,computational physics