Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Focus one percent - Energy-efficient indoor Air Quality system suitable for any building (FOCUS ONE PERCENT)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 420000.0
EU funding (EUR): 420000.0
Participants: 1
Project status: SIGNED

FOCUS 1%: It is a project for buildings in metropolitan areas with implications for the environment, the economy, and the health. More and more people live in cities, spend more time indoors and have less access to healthy air. According to the United Nations Environment Programme air pollution is a major global health crisis. It is the cause of one in nine deaths worldwide. Indoor air is usually more polluted than outdoor air, this is due to the fact that indoors, the pollutants from the outside are added to pollutants from the inside, which are produced by people, furniture, appliances, or building materials. For this reason, every day we move large quantities of air, in and out of buildings. To make matters worse, city air is often too cold, too hot or too polluted, so it takes a lot of effort to prepare it for indoor use. The amazing thing about all these efforts is that only 1% of the indoor air is unhealthy. The other 99% is good with gases such as nitrogen, oxygen, etc. We propose to focus on this 1%, neutralise its chemical, biological and comfort pollutants, and not move in and out of the building, the 99% that is good. It means energy and money savings, but there is a greater benefit, related to people's health, medical costs, sick leaves, hospital infections and, ultimately, improving people's quality of life.

Keywords: particularly suitable for existing buildings,refurbishments and renovations
Certification for Cybersecurity in EU ICT using Decentralized Digital Twinning (COBALT)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Increased Cybersecurity
Action type: Innovation actions
Countries involved: Greece,Germany,Spain,Belgium,Cyprus,France,Romania
Call: Development and validation of processes and tools used for agile certification of ICT products, ICT services and ICT processes (HORIZON-CL3-2022-CS-01, 2022)
Start date: 2023-11-01
End date: 2026-10-31
Duration (months): 36.0
Total project cost (EUR): 5983793.75
EU funding (EUR): 4996405.63
Participants: 14
Project status: SIGNED

COBALT proposes the introduction of a Common Certification Model (CCM) for European industries, leveraging existing standards and composing a unified cybersecurity namespace for ICT processes. The proposal will uphold the paradigm of Digital Twinning (DT) via the creation of Digital Threads and extend it in a vertical agnostic approach across different industries, including Quantum computing (involving FHG’s Quantum Computer) and I4.0. The COBALT DT will explore technology disruption mainly focusing on AI and High-Performance Computing (HPC) via the analysis and certification of Quantum Processing Oracles (a Quantum Computer exposure operation that is used as input to another algorithm), and how different enablers of these paradigms can be certified in a vertical agnostic manner. Quantum is destined to play a pivotal role in Europe’s AI and Computing sovereignty, thus protecting such infrastructure and its relevant processes (Quantum Oracles), should be of top priority. Along with common information models, COBALT acknowledges the importance of trusted information exchange a critical feature for an effective certification process across different industries, especially regarding cybersecurity. Therefore, COBALT will focus on the integration of International Data Spaces (IDS) primitives as a basis for the data sharing platform across different stakeholders. IDS currently proposes different models and procedures to share information and data across different spaces in a trusted manner between two parties, this can facilitate the process to build a trusted end-to-end certification framework across different industry stakeholders. Finally, COBALT aims to build a decentralized solution to further accelerate technology adoption and harmonization for the different use cases to be adopted. For the proposed CCM to function as a long term and sustainable European solution for certification, it needs to adapt and flex according to different environment conditions.
Developing a Rapid, Home-Based Urine Test to Differentiate Bacterial and Viral Respiratory Infections (AccUrine)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Israel
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

AccUrine, founded in 2022 by Dr. Shani Shenhar-Tsarfaty (CTO) and Yael Schneidman (CEO), has developed an innovative urine-based proteomic platform for rapid, at-home disease diagnosis and monitoring. The company's inaugural product addresses a pressing global health issue: distinguishing between viral and bacterial infections in acute respiratory infections (ARIs). ARIs cause an estimated 1.3 million deaths annually among children under 5 in developing countries and over 1.6 million deaths among adults aged 70 and older worldwide. The global infectious respiratory disease diagnostics market, valued at USD 39.20B in 2025, presents a significant opportunity for AccUrine's kit. AccUrine's differential diagnosis tool, backed by a patent and a database of over 750 samples, boasts sensitivity and specificity of >85%. This cutting-edge technology meets the critical need for accurate, rapid diagnostics in respiratory infections, potentially curbing unnecessary antibiotic use and enhancing patient outcomes. AccUrine has established strong partnerships with the Tel-Aviv Medical Center and Weizmann Institute, and have acquired an exclusive license, building upon more than five years of research led by Dr. Shenhar-Tsarfaty, Prof. Rogowski, and Prof. Berliner. This collaboration has resulted in a robust and validated platform with the potential to transform disease diagnosis and monitoring. AccUrine has raised $1.86M in SAFE agreements from angel investors and private investors, including experienced biomedical investors. Additionally, it has secured grants totaling $1.15M from the Israeli Innovation Authority, with an additional $1.3M pending approval. At TRL 7, AccUrine is now conducting early clinical trials at 5 sites with plans to open another recruitment site. AccUrine is well-positioned to significantly impact healthcare's future. It aims to improve patient outcomes and contribute to more efficient, cost-effective healthcare systems worldwide.

Keywords: viral respiratory infections,bacterial respiratory infections,home based urine test,urine test
Deciphering Split Monopoiesis Impact on Tissue Macrophages (MONOSPLIT)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Immunity, Infection and I mmunotherapy
Panel description: The immune system , related disorders  and their mechanisms , biology of infectious agents and infection, biological basis of prevention and treatment of infectious diseases , innovative imm unological tools and approaches , including  therapies
Countries involved: Israel
Call: ERC ADVANCED GRANTS (ERC-2024-ADG, 2024)
Start date: 2025-12-01
End date: 2030-11-30
Duration (months): 60.0
Total project cost (EUR): 2499990.0
EU funding (EUR): 2499990.0
Participants: 1
Project status: SIGNED

Macrophages are key players in organ development, tissue maintenance, and the immune defense of vertebrate organisms. These cells are initially established during embryonic development, but most tissue-resident macrophage compartments are progressively seeded and often even replaced by monocyte-derived cells. Monocytes and their macrophage progeny critically contribute to a wide range of pathologies, including autoinflammatory, cardiovascular, and metabolic disorders, as well as cancer. Given their central role in physiology and pathophysiology, these cells are attractive targets for therapeutic intervention. This will, however, require an in-depth understanding of monocyte-to-macrophage trajectories, whose comprehensive study in mice and man is the goal of this proposal. Beyond these translational implications, our studies are particularly well-timed, given new exciting findings: thus, monocytes were recently shown to arise from distinct developmental trajectories, and we discovered that this developmental monocyte dichotomy translates into tissue macrophage heterogeneity with probable significant functional impact. Here, we propose to follow up on our recent intriguing finding and use murine fate mapping and novel Csf1r-targeted genetic perturbations, combined with a high-resolution single-cell-based imaging and omics analysis of murine and human blood, to explore the impact of developmental monocyte dichotomy on health and disease in man and mice. An in-depth understanding of the two monocyte trajectories, their differential dominance following infections, and differential fates in distinct tissues will have significant value for the future development of strategies for tissue macrophage manipulation. Moreover, our detailed analysis of human blood might incentivize routine monitoring of the monocyte-to-macrophage axis for diagnosis.

Keywords: monocytes,macrophages,bacterial and viral infections,hematopoiesis,lineage tracing,degron based perturbation,lung,intestines,blood
Interactions with Future Reach-Through Volumetric Displays (InteVol)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Computer Science and Informatics
Panel description: Informatics and information systems, computer science, scientific computing, intelligent systems
Countries involved: Spain
Call: ERC STARTING GRANTS (ERC-2021-STG, 2021)
Start date: 2022-10-01
End date: 2027-09-30
Duration (months): 60.0
Total project cost (EUR): 1495965.0
EU funding (EUR): 1495965.0
Participants: 1
Project status: SIGNED

Displays in the shape of televisions, computer screens or phones are ever present in our education, work and entertainment. However, they do not take full advantage of our inner spatial abilities that we have to interact with the real world. True 3D displays can provide the same visual clues as the real world without forcing the users to wear devices. However, with State of the art (SoA) displays, the users cannot reach inside the display volume to directly interact with the virtual objects as they would do in real life. We envision a volumetric display capable of projecting true 3D virtual objects in mid-air that can be reached by the users to enable direct interaction, i.e. a reach-through volumetric display (RVD). This vision has been presented in multiple movies and books but there is no realization. Three novel technologies will be developed and combined to create an RVD. 1) fast time-multiplexed acoustic fields will create virtual force fields that give shape to microfabricated light-scaterring particles. 2) Tomographic illumination will shine on the particles as a more scalable alternative to phase-based holographic. 3) Volumetric tracking of the particle distribution will control the previous technologies in a closed-loop manner. Applications will serve as benchmarks to test novel interaction techniques and develop a framework that fills in the knowledge gap for interactions with as yet nonexistent RVDs. The objectives of the project are: O1) find a set of technologies that enables the realization of RVDs, O2) create interaction techniques for RVDs and categorize them using a framework that will be applicable to future displays, our current frameworks for 3d-interactions may not be applicable to RVDs. O3) enhance an RVD with tactile sensations, spatial audio and study its effects on humans. The PI is uniquely qualified with experience in designing mid-air interactions and using levitated particles for displays.

Keywords: acoustic levitation,true 3d,direct inteaction,acoustic force fields,microfabrication,tomographic illumination,natural interaction
Higher Order Parton Showers and Resummation to meet the High Luminosity LHC's accuracy goal (HOPSRES)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Switzerland,United Kingdom
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-10-01
End date: 2026-09-30
Duration (months): 24.0
Total project cost (EUR): 210789.12
EU funding (EUR): 210789.12
Participants: 2
Project status: SIGNED

With the upcoming high-luminosity phase of the Large Hadron Collider (LHC), the high energy physics community is gearing up to explore the fundamental building blocks of our universe with unprecedented precision. Consequently, the demand for precise and widely available theoretical predictions is at its highest level. Resummation of logarithmically enhanced terms plays a crucial role in achieving accurate phenomenological predictions, in addition to higher-order fixed-order predictions. During my fellowship, I will to work on the design, implementation, and application of tools dedicated to Next-to-Next-to-Leading Logarithmic (NNLL) resummation, including novel applications, as well as the first complete dipole parton shower with validated NNLL accuracy. Both represent critical tasks to meet the accuracy needs of the next phase of the LHC and of future collider experiments. As a first step, I intend to extend the established CAESAR formalism for NLL resummation to NNLL, inside a comprehensive framework within the Sherpa event generator, one of the major simulation tools used by the LHC experiments. The Sherpa-CAESAR framework will then be extended to accommodate hadron collider environments like the LHC. The integration of this baseline for NNLL resummation serves as a foundation for the following efforts. Subsequently, I plan to enhance the recently introduced Alaric parton shower with inclusion of established Next-To-Next-To-Leading Order (NLO) splitting functions. Ultimately, I will utilise the tools and methods developed in the initial phase to validate the NNLL accuracy of the enhanced Alaric parton shower. By the project’s conclusion, not only will a significant enhancement in NNLL resummation have been realised, but novel novel strategies for NLO subtraction and parton shower matching will emerge. This project stands to make a substantial contribution to the advancement of particle physics and the successful execution of experiments at the LHC and beyond.

Keywords: collider physics,quantum chromodynamics,resummation,parton showers
Experimental production capabilities for quantum technologies in Europe (Qu-Pilot)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Cluster 4 other
Destination: Other Digital, Industry and Space destinations
Action type: Research and Innovation actions
Countries involved: Finland,Netherlands,Belgium,France,Germany,Austria,Italy,Spain,Czechia
Call: HORIZON-CL4-QUANTUM-06-SGA - Supporting experimental production capabilities for quantum technologies in Europe (SGA) (HORIZON-CL4-2022-QUANTUM-06-SGA, 2022)
Start date: 2023-04-01
End date: 2026-09-30
Duration (months): 42.0
Total project cost (EUR): 18999992.0
EU funding (EUR): 18999992.0
Participants: 21
Project status: SIGNED

The Qu-Pilot SGA proposal consists of 21 partners from 9 different countries aiming to develop and provide access to the first, federated European fabrication (production) capabilities for quantum technologies, building on and linking together existing infrastructures in Europe. Qu-Pilot will implement the first stage of the capability innovation roadmap for providing experimental (pilot) production capabilities and a roadmap for transferring such capabilities to an industrial production environment, as was proposed in the awarded FPA. It will provide experimental production capabilities for quantum technologies in computing, communication and /or sensing through 13 service-provider organizations available to users, including industry, in particular SMEs and contribute to developing European standards in the field. Qu-Pilot will provide services for the development of a European supply chain of quantum technologies, provide European industry, especially start-ups and SMEs, with the necessary innovation capacity, and make sure that critical IP remains within the EU. The initial service offering will be validated through use-cases with companies within the SGA. A minimum of 20 such use-cases are expected and of those 11 are already part of this Qu-Pilot SGA proposal. The competence development, industrial use-cases and ecosystem building – all the activities identified and set out in the FPA will have first set of implementation through this first SGA.

Keywords: quantum,technologies,pilot line,computing,communication,sensing
Integrated microcomb system chip using heterogeneous integration (IMCSC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Sweden
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-04-01
End date: 2027-03-31
Duration (months): 24.0
Total project cost (EUR): 236340.0
EU funding (EUR): 236340.0
Participants: 1
Project status: SIGNED

Optical frequency combs (OFC) play an essential role in precision, timing and navigation applications. Integrated photonics facilities the development of OFC-based applications towards chip-scale miniature package. Most applications require detecting the radio frequency (RF) signals of a OFC (i.e. repetition rate and carrier-envelope offset frequency). Thus, an important step towards miniaturized complex OFC systems is to integrate the OFC generation with the auxiliaries components required for detecting its RF signals onto the same chip. This project aim to develop an integrated microcomb system chip with accessible RF signals detection using heterogeneously integrated photonic platforms. Silicon nitride (SiN) platforms have shown their superiority in comb generations using microresonators (i.e. microcomb), with octave-spanning spectrum and dispersive wave emissions that enable detection of the carrier-envelope offset frequency via f-2f self-referencing process. Thin-film lithium niobate (TFLN) platforms are advantageous in second-order nonlinear frequency conversions and electro-optics modulations, the former can be applied for the f-2f process, while the latter is widely used for frequency down-converting the high-frequency repetition rate of a microcomb. Therefore, this project will explore heterogeneous integration technique to combine the SiN microcomb generator with TFLN devices for f-2f process and frequency down-conversion on a single chip. Specially, a novel photonic molecule structure will be explored for power-efficient octave-spanning microcomb generation with strong dispersive wave emission. A broadband electro-optics frequency comb will be developed for frequency down-conversion of microcomb repetition rate. Periodically poling of TFLN waveguide will be explored for frequency doubling in f-2f process. Heterogeneous integration will bring together all these components to deliver an integrated microcomb system.

Keywords: optical frequency comb,integrated photonics,heterogeneous integration
Photocatalytic Reactions Under Light and Dark with Transient Supramolecular Assemblies (PhotoDark)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Countries involved: Italy
Call: ERC STARTING GRANTS (ERC-2022-STG, 2022)
Start date: 2023-10-01
End date: 2028-09-30
Duration (months): 60.0
Total project cost (EUR): 1494500.0
EU funding (EUR): 1494500.0
Participants: 2
Project status: SIGNED

The efficient conversion of solar energy into molecular fuels has been recognized as one of the grand challenges facing society today. This is motivated by the urgent need to develop affordable, reliable, sustainable modern energy as a way to address the problems arising from the burning of fossil fuels and global warming. Rapid progress is being made in the development of photocatalytic systems that use directly solar light to produce fuels but do so only during daylight. This is a significant oversight, as the overall processes are inefficient due to the intermittent nature of the solar energy source. The next frontier in energy conversion, and the key objective of my proposal, are smart materials that perform photocatalysis under irradiation and, in addition, can trap and concentrate (sun)light to then use it for catalysis under low or no illumination. To achieve this ambitious goal, TENEBRIS aims to develop an unprecedented strategy to enable dark or persistent photocatalysis by using self-assembled materials. TENEBRIS will (i) provide missing insights into light-driven supramolecular polymerization, (ii) deliver smart, autonomous and transient self-assembled materials that perform photocatalysis also under dark, and (iii) establish design principles to be generally applicable for tailor-made (nano)materials with functions unattainable through conventional methods. The fundamental outcomes of this research will lead to non-incremental advances in various chemical research areas (photocatalysis, out-of-equilibrium supramolecular chemistry, and materials science and engineering) and to a substantial impact beyond them.

Keywords: dissipative self assembly non equilibrium systems out of equilibrium chemistry