Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
A multilevel integrative approach to microbial ecology: from molecular networks to cellular interactions in a spatially structured community (MultiMEc)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-08-01
End date: 2023-07-31
Duration (months): 24.0
Total project cost (EUR): 203149.44
EU funding (EUR): 203149.44
Participants: 1
Project status: CLOSED

Microbial communities profoundly influence global biogeochemical cycles and human life. Understanding their wiring is crucial to manage, rationally manipulate, or de novo assemble communities for environmental, industrial or medical applications. However, studying the complex web of microbial interactions and how they are affected by the spatial structure of the community is experimentally challenging. Here, I propose an integrative approach to dissect microbial interactions in a synthetic community consisting of two bacterial species of the human gut microbiota, the commensal Escherichia coli and the probiotic lactic acid bacterium Lactobacillus plantarum. These two species were predicted to engage in exploitative and mutualistic metabolic interactions depending on oxygen availability and provide an experimentally tractable and possibly health-relevant model community. I will employ a combination of highly sensitive quantitative analyses on the molecular level (proteomics, metabolomics, CRISPR/Cas9 genetic perturbations) with quantitative analyses on the individual cell and community level (cellular growth rates and spatial organization) to obtain a comprehensive mechanistic understanding of the interactions between the two species. The multilayered nature of the approach, including the conceptualization of the interactions with a mathematical model, is expected to provide novel insights into the fundamental principles underlying microbial interactions and how they are affected by the environment. Furthermore, a detailed understanding of the molecular interactions of L. plantarum with other gut residents could inform the rational modulation of the gut microbiome to treat diseases associated with dysbiosis. This fellowship would have a major impact on my career by facilitating re-integration into the European research landscape. It would allow me to acquire a unique and competitive scientific profile and to establish my own niche in the field of microbial ecology.

Keywords: microbial ecology,microbial interactions,microbiome,quantitative single cell biology,microfluidics
Minority Languages, Major Opportunities. Collaborative Research, Community Engagement and Innovative Educational Tools (COLING)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Research and innovation staff exchange
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy,Poland,Poland,Poland,Latvia,United States,Netherlands,Netherlands,Netherlands,Mexico
Call: Research and Innovation Staff Exchange (H2020-MSCA-RISE-2017, 2017)
Start date: 2018-01-01
End date: 2023-09-30
Duration (months): 69.0
Total project cost (EUR): 1687500.0
EU funding (EUR): 1579500.0
Participants: 14
Project status: SIGNED

The linguistic and cultural diversity of Europe is crucial to the capacity for problem solving and creative thinking upon which our general wellbeing and economic prosperity depend in an increasingly global and technological society. However, language diversity and immigration are often seen as threats and are challenged by discriminatory attitudes and state policies. COLING will provide justification for the strengthening and revitalization of minority languages, as well as guidelines to implement concrete programs for this purpose. The project’s objectives focus on developing and sharing expert knowledge on language revitalization programs that combine community-driven and top-down approaches; promoting engaged collaboration among academic, nonprofit and community-based institutions; developing efficient teaching methodologies, teacher training, and curricula for minority languages; establishing a new international academic program in minority studies at the partner institutions, in which the new methodologies and curricula will be employed. To this end, COLING affiliated researchers will work together to a) document and archive linguistic-cultural diversity and language practices of indigenous communities and migrants; b) explore the Trans-Atlantic perspectives and historical ties between the Americas and Europe that demonstrate the cultural resilience of indigenous peoples and the evolution of heritage cultures in mixed societies; c) develop innovative teaching methodologies through content modules in textual and digital formats and d) investigate the causative and correlative relationships between language identities, linguistic and cultural discrimination, self-confidence, trauma and well-being, and social cohesion in multilingual and multicultural contexts. COLING will organize summer schools, workshops, trainings to bring together researchers, practitioners and community members, permitting the exchange of skills, best practices and research results.

Keywords: language revitalization and endangerement,engaged humanities,participatory action research
Opinion Dynamics (DYNNET)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Individuals, Markets and Organisations
Panel description: Economics, finance and management
Countries involved: United Kingdom
Call: ERC Starting Grant (ERC-2018-STG, 2018)
Start date: 2018-12-01
End date: 2023-05-31
Duration (months): 54.0
Total project cost (EUR): 830623.0
EU funding (EUR): 830623.0
Participants: 1
Project status: SIGNED

In this project I propose to study opinion dynamics in social networks and groups. In particular, I will ask how opinion dynamics contribute to shape social identity and how, conversely, social identity affects communication. I also ask whether and when social identity is a barrier to communication, when “opinion bubbles” are created and when and how “fake news” can spread. The types of social identity I consider include social class, ethnicity and gender. The project consists of four subprojects. The first subproject [A] focuses on communication between social classes and inequality. The subproject asks how opinion dynamics contribute to diverging experiences, core behaviours and values that go much beyond income inequality. I will first document this divergence by conducting experiments in a representative sample of the UK population via the UK Household panel and then conduct lab experiments to study opinion dynamics and the conditions under which “opinion bubbles” arise in more detail. Subproject [B] focuses on gender bias in committees. A large body of empirical evidence has documented gender biases in decisions, such as hiring, promotion, or performance evaluations. Many of these decisions involve communication and deliberation among committee members. Nevertheless the role of opinion dynamics in committees in creating or amplifying gender bias has not been explored. Subproject [B] aims to fill this gap. Subproject [C] will focus on how perceived uncertainty contributes to the spread of discriminatory attitudes with a particular focus on ethnic discrimination. Subproject [C] will be conducted both using a representative sample of the UK population via the Innovation Panel of Understanding Society, the UK Household panel as well as lab experiments. The last subproject [D] will use lab experiments to study under which conditions opinion dynamics can become vulnerable to “fake news”.
Exploiting strong light-matter coupling for organic polariton-based photonic devices (PolDev)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-05-01
End date: 2023-04-30
Duration (months): 24.0
Total project cost (EUR): 174806.4
EU funding (EUR): 174806.4
Participants: 1
Project status: CLOSED

The coherent coupling of photons and material resonances, known as strong light-matter coupling, has recently emerged as a concept to realise a variety of novel devices. By hybridising light in a micro- or nano-scale cavity with a material resonance, often an exciton to create exciton-polaritons, properties of both light and matter can be manipulated. While this has shown great promise in systems that exploit a change in energy levels of a material, such as in polariton chemistry, the resulting change of light dispersion has been largely neglected for applications. Within the project PolDev, I aim to realise organic polaritonic devices that make full use of the exciton-like dispersion in ultra-strongly coupled microcavities with suitable detuning. In doing so, I will realise interference-based transmission filters with ultra-low angular dispersion that will enable a new way of designing optical systems. I will further exploit this concept to design high-Q microcavity polariton light emitting diodes for display applications with unprecedented colour purity and to showcase new pathways for electrically pumped polariton lasing. The resulting devices will further be ported onto mechanically flexible platforms, paving the way for novel polaritonic applications.

Keywords: strong light matter coupling,polaritons,dispersion,optical filters,organic light emitting diodes
Narration, linguistic expression and discourse structure: explorations of orality in Occitan and French (EXPRESSIONARRATION)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-04-01
End date: 2018-08-18
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

This project is an exploration of the linguistic complexities around the concept of ‘orality’, as attested in different expressions of ‘oral narrative’ in Occitan and French. It will be corpus-based and comparative, looking at a key set of temporal features in narratives collected in a traditional oral setting, in contemporary oral settings and in published ‘literary’ versions of oral narratives. Crucially, the project seeks to revisit the definition of ‘orality’ and to contribute to novel conceptual models. Outputs will take the form of peer-reviewed journal articles, a unique digitised Occitan corpus, digital annotation tools, conference papers and an intersectoral workshop. Given the location of this MSCA in Belfast, and the importance of oral storytelling in Irish cultural heritage, an integral part of the project involves public engagement around cultural practice and minorised languages, and the establishment of links between cultural sectors internationally. The supervisor’s (JC’s) expertise both overlaps with, and complements the experienced researcher’s (MV’s) skills, such that the project will be of mutual benefit at both individual and institutional level. In line with MSCA objectives, the experienced researcher will diversify her research skills (theoretical, analytical and digital), will benefit from excellent linguistic, research and professional training, and will enhance her career profile through international and intersectoral mobility.

Keywords: linguistics,occitan language,french language,language and orality,oral narrative,oral storytelling,discourse relations,temporality,framing,discourse structure,corpus digitisation
Control of leishmaniasis, from bench to bedside and community (EUROLEISH-NET)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Ethiopia,Germany,Spain,Spain,Spain,Switzerland,Belgium,Sweden,Belgium,Tunisia,Belgium,France,Czechia,United States,United Kingdom,United Kingdom,United Kingdom,Portugal,Portugal
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 3820537.8
EU funding (EUR): 3820537.8
Participants: 29
Project status: CLOSED

Leishmaniasis control is the topic for EUROLEISH-NET, a Marie Sklodowska-Curie – Innovative Training Network. Leishmaniasis is a neglected infectious disease and a major public health and veterinary problem that afflicts both developing countries and Europe. The current technological and epidemiological advances underpin the necessity to develop training programmes aiming at developing new tools and strategies to control of leishmaniasis. An excellent group of academic and non-academic institutions in Europe and abroad will host 15 PhD students who will receive training in this programme. The expertise and training that will be offered ranges from parasitology to molecular science, genetics, epidemiology and strategic interventions. The 15 research projects designed encompass drug discovery, drug resistance, diagnostics and vaccine development, population genetics, vector control and integrated control programmes. The designated project supervisors have proven track records of success in research and in training. The incorporation of trainee mobility into the network, together with the commitment, strong affiliations and technology transfer between the participants provide a highly synergistic framework for success. The EUROLEISH-NET coordinators have proven experience in laboratory, field, administrative and financial management, supported by a meticulously planned series of meetings and diligent monitoring of the progression of each researcher. We anticipate an extremely productive training and research output from EUROLEISH-NET. We expect to train the next generation of leading research scientists in this field, endowed with skills that are broadly and internationally transposable.

Keywords: leishmaniasis,neglected infectious diseases,zoonosis,disease control
Hydrogen Engine Architecture Virtually Engineered Novelly (HEAVEN)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Public-private partnerships
Destination: Clean Aviation
Action type: Innovation actions
Partnership: CLEAN-AVIATION (JU-JTI)
Countries involved: United Kingdom,Germany,Spain,France,Netherlands
Call: Ultra Efficient Propulsion Systems for Short and Short-Medium Range Aircraft (HORIZON-JU-Clean-Aviation-2022-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 35639788.5
EU funding (EUR): 29906036.25
Participants: 20
Project status: SIGNED

Climate-neutral aviation will require the use of alternative fuels such as Green Hydrogen and Sustainable Aviation Fuel (SAF) combined with the power density of an ultra-efficient gas turbine engine for the Short and Medium Range (SMR) aircraft market which corresponds to approximately 50% of the current share of air transport emissions. Rolls-Royce (represented within the HEAVEN project by RR-UK & RR-D) supported by key UK and European academia, industry and research centres are currently developing a new generation of very high bypass ratio geared engine architecture called UltraFan® which was started in 2014. From the beginning this ducted engine architecture has been designed to be scalable and meet the needs both of widebody and SMR markets. To achieve the necessary 20% fuel burn reduction Rolls-Royce proposes to significantly evolve the UltraFan design. The evolved engine architecture design will take the next steps in improving the efficiency of the gas turbine, take advantage of the properties of net zero carbon fuels such as Hydrogen to improve efficiency, combining this with Hybrid electric technology to reduce wasted energy. Numerous innovative enabling technologies already at TRL3 will be incorporated into this new architecture to improve the gas turbine efficiency. Together with work on Hydrogen in CAVENDISH (HRA-01) and Hybrid Electric in HE-ART (HER-01) Clean Aviation projects in conjunction with activities in national and regional programmes, this will be synergistically combined to validate up to TRL6 the highly innovative UltraFan design to support a 2035 EIS. HEAVEN brings together a highly specialised European industrial and academic consortium already strongly involved and familiar with the UltraFan programme. Additionally, the partner easyJet, European airline operator who have the largest fleet of European manufactured SMR aircraft operating in Europe, will bring an in depth knowledge of operational requirements and impact in this market.

Keywords: aerospace engine efficiency,engine architecture,hybridisation,combustion,hydrogen,saf fuel,advanced cycles,propulsion system,geared,innovative,disruptive,net zero,sustainable,scalabcycles
improving Reproducibility In SciencE (iRISE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Reforming and enhancing the European R&I System
Theme: Reforming and enhancing the European R&I System
Destination: Reforming and enhancing the European R&I System
Action type: Research and Innovation actions
Countries involved: Croatia,Sweden,Netherlands,Switzerland,Germany,United Kingdom,Finland,Spain,Cyprus
Call: Increasing the reproducibility of scientific results (HORIZON-WIDERA-2022-ERA-01, 2022)
Start date: 2023-09-01
End date: 2026-08-31
Duration (months): 36.0
Total project cost (EUR): 1447271.25
EU funding (EUR): 1446771.25
Participants: 17
Project status: SIGNED

Structured understanding of the drivers of irreproducibility and presenting concrete solutions of tools and interventions will help to increase the quality, reliability and re-usability of scientific evidence. To this end, iRISE proposes to provide theoretical and empirical evidence of the effectiveness of specific interventions, and a framework for a robust, evidence-based road map for the development, assessment and implementation of interventions intended to improve reproducibility. iRISE brings together qualitative and quantitative expertise, from academia and SMEs, including meta-science, statistics, economics, artificial intelligence, research ethics and integrity, quality assurance, and project management. iRISE proposes the development of a general framework for diagnosing and addressing reproducibility problems using analytical and computational modelling, simulations and meta-studies. Data on existing interventions will be systematically curated and evaluated, and stakeholders will be consulted to collaboratively identify practices and tools that should be prioritised for implementation. iRISE proposes to conduct empirical studies of both technical and practice-based solutions to increase reproducibility. Across all iRISE activities, the influences of research culture will be investigated, with a focus on mainstreaming systematic integration of equity, diversity and inclusion practices. A comprehensive Stakeholder Forum will be engaged to provide advice, and iRISE will commit to open and reproducible practices. The different types of evidence generated will be integrated into an open knowledge base to support the community in decision-making to identify, test, and implement effective and feasible solutions for reproducibility. The members of iRISE have made pivotal scientific and policy contributions relating to robustness, rigour and reproducibility in the past and have the skills and tools to succeed in this ambitious project that has potential scientific, economic and societal gains both in Europe and beyond.

Keywords: reproducibility
Non-equilibrium optically levitated interacting nanoparticle arrays (NEOVITA)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Austria
Call: MSCA Postdoctoral Fellowships 2022 (HORIZON-MSCA-2022-PF-01, 2022)
Start date: 2023-04-01
End date: 2025-03-31
Duration (months): 24.0
Total project cost (EUR): 183600.96
EU funding (EUR): 183600.96
Participants: 1
Project status: CLOSED

We propose the exploration of many-body quantum physics with a new experimental platform, based on the optically levitated and cooled arrays of spherical nanoparticles with strong and controllable interactions. The recent works by the host institution demonstrated the cavity assisted cooling of a single nanoparticle to its motional quantum ground state as well as the simultaneous trapping of two nanoparticles with full control over the interactions between them. In this work we shall extend these results to the multiple particles. This will be on the one hand an important milestone towards achieving the many-body regime and on the other hand, the first observation of the cavity assisted cooling of an array of nanoparticles via coherent light scattering. The realisation of this milestone will enable us to study the system’s non-equilibrium relaxation after precise perturbation protocols. Using the natural isolation from the environment, we shall study the thermalisation of a nearly isolated few-particle quantum system. Depending on the energetic landscape, as well as on the nature and range of interactions, we expect to observe motional pre-thermalisation, or the absence of thermalisation with the onset of the Anderson localisation or the Many-Body Localisation of phonons. Finally, we shall explore the controllable non-reciprocity of the inter-particle interactions by breaking the directional symmetry of the inter-particle forces by conferring to them the direction dependent phases. Combining this with the dissipative nature of these forces, we aim at implementing a specifically tailored non-hermitian Hamiltonian describing the constant intensity waves.

Keywords: quantum optics,cavity light matter interaction,out of equilibrium phenomena,non hermitian quantum mechanics,non reciprocity