Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
An online software platform for effectively matching investors with start-ups, focused on boosting the cleantech sector (CAGIX)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Action type: SME instrument
Countries involved: Italy,United Kingdom
Call: SME business model innovation (H2020-SMEINST-1-2015, 2015)
Start date: 2015-10-01
End date: 2016-01-31
Duration (months): 4.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 2
Project status: CLOSED

CAGIX is a software company, with long-term experience in the start-ups, incubation and investment industry, which has developed an online incubation platform that covers investment preparation, incubator operations and portfolio company management. The investor ecosystem is fragmented and opaque and attracting investment is a lengthy process. Early stage start-ups often have little knowledge of business planning or fund-raising procedures and therefore deals can be perceived as risky. Currently, there is no system on which investors can search for valuable start-up industries abroad. Start-ups and innovation need to be better managed through technology to achieve results; technology has the potential to make incubation, investment preparation and capital transactions more efficient, highly scalable and less expensive. CAGIX’s software platform offers start-ups a proven efficient path to build up the perfect investor package and provide the relevant information needed by investors. This facilitates the due diligence of interested investors, saving time and expenses and guaranteeing a high quality standard and uniformity for the deals. The CAGIX platform hosts an innovative proprietary deal search engine which when applied to the start-up database enables investors to meet companies raising money and carry out faster transactions through CAGIX’s streamlined process. The platform is specifically focused on CLEAN-TECH and climate change hosting eighteen diverse sectors within the field including biofuels, hydropower, recycling and transportation. Within the overall project, CAGIX aims to: standardize the design of the website and information portrayed to investors; localize the platform to support foreign currencies and languages; address local financial laws/regulations for investors across Europe; establish a sound marketing and commercialization strategy and launch at least 3 pilots in 3 EU countries with the involvement of end-users, incubators and investors.

Keywords: capital investment,software platform,climate change,learner algorithm
Nanofluids as working fluids for organic Rankine cycles (NanoORC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Denmark
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-03-01
End date: 2020-02-28
Duration (months): 24.0
Total project cost (EUR): 200194.8
EU funding (EUR): 200194.8
Participants: 1
Project status: CLOSED

Organic Rankine cycles have gained great interest over the last decade as an efficient technology to convert low-temperature heat, from renewable energy or industrial waste, to electrical power. For this reason, they are expected to play a substantial role in the future European energy system, as they will contribute to reduce the dependence on fossil fuels and the CO2 emissions associated to power generation. However, recent regulations that limit the use of ozone depleting substances and greenhouse gases will phase out most of the working fluids currently used in organic Rankine cycles. As a result, there is an urgent necessity to search for alternative fluids that meet the thermodynamic requirements of the replaced ones, and offer better environmental and safety features. The addition of nanoparticles to fluids (nanofluids) can enhanced their thermal properties, thus making them an optimal solution for their use in organic Rankine cycles. The main barrier for the introduction of these innovative fluids comes from the lack of an accurate knowledge of their behavior. NanoORC aims at developing a general model for the estimation of the thermophysical and transport properties of nanofluids, to evaluate their potential for organic Rankine cycles. The novelty of the project lies on the use of group contribution methods to develop a generalized model that will be integrated as a property library into simulation software. The host will provide the fellow established knowledge on organic Rankine cycles, and train her on state-of-the-art simulation and optimization tools. The fellow will bring expertise on thermophysical properties of fluids, not currently available at the host institution, to introduce the research on innovative working fluids. The fellow will complete her training through a collaboration with the National Institute of Standards and Technology and a secondment at Turboden, which will be essential for the transfer of the knowledge derived from NanoORC.

Keywords: organic rankine cycles,renewable energy,nanofluids,thermophysical properties,power generation,waste heat recovery
Implications of tissue stiffness in growth control during limb regeneration in salamanders (Ambystoma mexicanum) (ProxDistReg)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-05-01
End date: 2023-04-30
Duration (months): 24.0
Total project cost (EUR): 174806.4
EU funding (EUR): 174806.4
Participants: 1
Project status: CLOSED

In several regenerating organisms it has been observed that distally amputated structures grow slower than proximally amputated ones, resulting in an overall time of regeneration that is independent of the tissue to be reformed. This observation suggests that cell proliferation or cell size could be adjusted with the plane of amputation along the proximo-distal (PD) axis, leading to an interesting scaling behaviour. It has been proposed that positional identity in the limb may be encoded as a proximal-to-distal gradient of cell surface molecules, that would in turn alter intercellular adhesions. Thus, it is possible that such differential adhesions are associated to the control of cell growth during regeneration. The central aim of this proposal is to address this question by combining cell biology, mathematical and physical tools, with the ultimate goal of understanding how the biomechanical properties of tissues affect regeneration, which may have important implications for the design of biomaterials aimed at being used for regenerative medicine. We will tackle this question in the highly regenerative salamander species Axolotl mexicanum, in which limb regeneration is initiated regardless of the amputation plane, and the regenerating limb grows until its size matches the contralateral undamaged one. We will evaluate growth rate and cell cycle of regenerating limbs amputated at different levels, and mathematically describe cell proliferation patterns. We will characterize several cell surface and extracellular matrix molecules along the PD axis, and measure tissue mechanics in vivo. Furthermore, we will for the first time, evaluate the Hippo pathway in salamanders, an important modulator of cell growth in response to several physical inputs, as the causal link between increased tissue stiffness and decreased proliferation.

Keywords: limb regeneration,proximo distal axis,stiffness measurements,mechanotransduction
Transition towards environment-friendly consumer products by co-creation of an oxidoreductase foundry (OXIPRO)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable and competitive bio-based industries and supporting the development of a European bio-economy
Action type: Research and Innovation actions
Countries involved: Spain,Germany,Italy,Norway,Türkiye,Finland,Greece,Norway,France,Netherlands,Netherlands,Denmark,United Kingdom
Call: Enzymes for more environment-friendly consumer products (H2020-FNR-2020-2, 2020)
Start date: 2021-06-01
End date: 2025-05-31
Duration (months): 48.0
Total project cost (EUR): 5999775.0
EU funding (EUR): 5999775.0
Participants: 16
Project status: SIGNED

OXIPRO will contribute to the transition towards greener detergents, textiles, cosmetics and nutraceuticals by co-creating and co-developing an efficient oxidoreductase foundry under an interdisciplinary and systemic innovation approach, integrating high-performance computing and cutting-edge biotechnology. Oxidoreductases offer promising, yet underexploited solutions for enhancing sustainability in consumer products. Oxidoreductases are able to replace strong toxic and harmful oxidizers, create novel functionalities in substrates, transform waste to valuable products, and improve quality, appearance and durability of consumer products. In OXIPRO, a collaborative ecosystem and RRI framework will be created to guide the development of novel environmental-friendly oxidoreductase-based solutions in an oxidoreductase foundry: 1) Hygienization in liquid detergents to sustain low energy washing processes. 2) Develop a circular cotton-textile biobleaching process for reduction of energy, water and chemical consumption. 3) Improve the sensory quality of fish protein hydrolysates to facilitate new sustainable value chains and improve by-product utilization for clinical nutrition. 4) Replace polluting ingredients with natural polymers for sunscreen products with additional skin health promoting effects. OXIPRO will develop novel generic technology platforms: enzyme intelligence (in silico bioprospecting and evolution, machine learning) and enzyme technologies (microfluidic reactors, co-factor dependences, bio-degradable immobilization), which will enable a faster time-to-market of the OXIPRO developments. These platforms can be replicated to other enzyme families and industrial sectors. Taken together, OXIPRO’s interdisciplinary approach will contribute to broadening the application of enzymes in greener consumer products and to the overall sustainability and competitiveness of the European bio-based economy.

Keywords: oxidoreductases,in silico,supercomputing,consumer oriented,industry driven,circularity,textile,nutraceuticals,detergents,cosmetics,safety,science with and for society
Information Processing in Future Quantum Networks (IPQNet)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany
Call: Individual Fellowships (H2020-MSCA-IF-2018, 2018)
Start date: 2019-05-01
End date: 2021-04-30
Duration (months): 24.0
Total project cost (EUR): 162806.4
EU funding (EUR): 162806.4
Participants: 1
Project status: CLOSED

We are now at a crucial point in building a next generation of quantum networks that will completely change the way we communicate. The discovery of quantum physics has been revolutionary in the way scientists understand the fundamental laws of nature, but we are now approaching an era where this will have an impact on society as a whole. We are already living in an interconnected world and are continuously dealing with issues of security and protection of our private data. Quantum technologies will therefore become more and more relevant due to their potential for improved security and faster computation, especially since the experimental state-of-affairs has reached the point of real communication scenarios. This research project will examine how to process information on a quantum network, from theory to experiment. This will be achieved by exploring composability and modular synthesis of quantum and classical routines as parts of larger protocols for secure multiparty computation. To succeed in this modular view, we need to (i) examine and verify the quantum resources (modules) and (ii) address the routing of information and construction of resources (connecting modules). Only after going through these steps can we return to the end-term goal of the project, which is to give novel protocols that can securely, and realistically be implemented in the near future. To this end, I will work closely with experimental groups and the industry, in order to implement the theoretical protocols and achieve a global perspective on how to process information in future quantum networks.

Keywords: quantum communication,quantum cryptography
eNd to End scalable and dynamically reconfigurable oPtical arcHitecture for application-awarE SDN cLoud datacentErs (NEPHELE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Future Internet: Software, hardware, Infrastructures, technologies and services
Action type: Research and Innovation actions
Countries involved: Italy,Israel,Italy,Germany,Greece,Greece,United Kingdom
Call: Smart optical and wireless network technologies (H2020-ICT-2014-1, 2014)
Start date: 2015-02-01
End date: 2018-01-31
Duration (months): 36.0
Total project cost (EUR): 3053636.25
EU funding (EUR): 3053636.0
Participants: 7
Project status: CLOSED

Datacentre traffic is experiencing 2-digit growth challenging the scalability of current network architectures. The new concept of disaggregation exacerbates bandwidth and latency demands whereas emerging cloud business opportunities urge for reliable inter-datacenter networking. PROJECT will develop an end-to-end solution extending from the datacenter architecture and optical subsystem design to the overlaying control plane and application interfaces. PROJECT hybrid electronic-optical network architecture scales linearly with the number of datacenter hosts, offers Ethernet granularity and saves up to 94% power and 30% cost. It consolidates compute and storage networks over a single, Ethernet optical TDMA network. Low latency, hardware-level dynamic re-configurability and quasi-deterministic QoS are supported in view of disaggregated datacenter deployment scenarios. A fully functional control plane overlay will be developed comprising an SDN controller along with its interfaces. The southbound interface abstracts physical layer infrastructure and allows dynamic hardware-level network reconfigurability. The northbound interface links the SDN controller with the application requirements through an Application Programming Interface. PROJECT innovative control plane enables Application Defined Networking and merges hardware and software virtualization over the hybrid optical infrastructure. It also integrates SDN modules and functions for inter-datacenter connectivity, enabling dynamic bandwidth allocation based on the needs of migrating VMs as well as on existing Service Level Agreements for transparent networking among telecom and datacenter operator’s domains. Fully-functional network subsystems will be prototyped: a 400Gb/s hybrid Top-of-Rack switch, a 50Gb/s electronic-optical smart Network Interface Card and a fast optical pod switch. PROJECT concept will be demonstrated in the lab and in its operational environment for both intra- and inter-datacenter scenario

Keywords: application defined networking,dynamic optical hardware reconfiguration
Socs3 gene in oocyte maturation and fertilisation - a novel link between inflammation and infertility (OOCSOCS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Czechia
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2017-06-01
End date: 2021-07-31
Duration (months): 24.0
Total project cost (EUR): 142720.8
EU funding (EUR): 142720.8
Participants: 1
Project status: CLOSED

Increasing maternal age, a prevalent trend in developed countries, negatively influences oocyte quality and consequently female fertility – 5% of all couples experience fertility problems arising from a physiological source in the women. To develop novel approaches to prevent or treat infertility, a more complete understanding of oogenesis is required. The host laboratory has recently identified the Socs3 gene, to date associated only with roles in the immune system, as a novel strong candidate regulating oogenesis. The project exploits a genetic approach to ablate the Socs3 gene from the female germ-line and addresses the role of Socs3 gene during mouse oocyte maturation and fertilisation, e.g. in correct chromosomal segregation, followed by further detailed and cutting-edge functional characterisation. The results could lead to the identification of novel therapeutic targets to treat female infertility. Dr. Veselovska, coming from a world-renown institute, is joining a well-established early mammalian development orientated host group, within the Department of Molecular Biology at the University of South Bohemia. Synergies arising from this multidisciplinary proposal will benefit both host and applicant. In particular, Dr. Veselovska is bringing a wealth of highly relevant mouse oocyte experience and bioinformatics skills for genome-scale analyses that are currently an underrepresented skills set in the host laboratory and host institution, as well as her network of UK based collaborators. She will receive training that is both complementary to her current knowledge and skills and novel and highly contemporary in relation to the experimental approaches used. Consequently, the fellowship award will substantially further the Dr. Veselovska’s career ambitions to become an independent early mammalian developmental biologist within her native Central European region, and facilitate the under-represented exchange of ideas between Western and Eastern European countries.

Keywords: socs3,oocyte,meiosis,chromosome segregation,fertilisation
Investor Energy-Climate Action Toolkit - Developing the framework and platform for non state actors' contribution to the Paris Agreement (InvECAT)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Belgium,France,Netherlands,Kenya
Call: Making the energy efficiency market investible (H2020-EE-2017-CSA-PPI, 2017)
Start date: 2018-03-01
End date: 2020-11-30
Duration (months): 33.0
Total project cost (EUR): 1484737.5
EU funding (EUR): 1484737.5
Participants: 4
Project status: CLOSED

The InvECAT project aims to mobilize voluntary energy efficiency and sustainable energy investment by companies and financial institutions through the development of standardized frameworks and tools and outreach by critical convening and marketing powers (UNEP FI, and Bloomberg). The project will thus enable credible, standardized non-state actor (NSA) energy and climate commitments that directly contribute to the achievement of EU and global energy and climate goals. At its core, InvECAT develops a “toolkit” for energy and climate target setting and monitoring that companies, financial institutions, regulators and policy makers can exploit to support domestic and global energy and climate goals. Policy makers and governments will have access to a framework and standard templates to define NSA pledges and a monitoring platform tracking alignment to such goals. Companies and financial institutions, reached by large corporate and financial sector networks at WRI and WWF will access target-setting tools that track progress toward existing commitments and the ability to set more ambitious ones. The project will further achieve broad market acceptance through the first international standard measuring the finance sector’s contribution to the Paris Agreement. The work done through InvECAT will address all types of energy-climate actions, thus covering both sustainable energy and energy efficiency. It builds on market leading data and tool initiatives (e.g. H2020 SEI Metrics project) and commitment initiatives (Science Based Targets initiative and UNFCCC NAZCA portal), while integrating an expanded focus on energy efficiency. The market uptake of the toolkit by all stakeholders (companies, financial institutions, policy makers, civil society) is supported by the extensive outreach and strong networks that consortium members have developed in over 20+ years of experience.

Keywords: paris agreement,contributions,investors,financing climate action,measuring progress,non state actors,climate change
The ecological consequences of chemotypic variation of damage-induced volatile organic compounds in sagebrush (Artemisia tridentata) (CVVOC)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Finland
Call: Individual Fellowships (H2020-MSCA-IF-2017, 2017)
Start date: 2018-06-01
End date: 2020-05-31
Duration (months): 24.0
Total project cost (EUR): 179325.6
EU funding (EUR): 179325.6
Participants: 1
Project status: CLOSED

Plants have evolved an impressive defense system to combat herbivores. These defenses include morphological structures like spines and secondary metabolites that have toxic, repellent, or antinutritional effects on consumers. Many plant defenses are constitutively expressed, but some are induced in response to herbivore damage. Damaged plants emit volatile organic compounds (VOCs) into the environment that may induce defenses in adjacent, undamaged tissue or may be eavesdropped by neighboring plants, enabling them to prime their own resistance response prior to attack. While once controversial, this plant-plant communication resulting in a VOC-induced phenotypic response that reduces damage from attacking herbivores has been demonstrated in over 50 species. Recently, researchers have found distinguishing VOC blends among sagebrush (Artemisia tridentata) referred to as chemotypes. Field experiments demonstrated that communication between A. tridentata plants of the same chemotype resulted in less damage by herbivores compared to that between plants of different chemotypes. Chemotypes were also found to be highly heritable. This is consistent with the hypothesis that volatile communication evolved as a within-plant warning mechanism due to limited vascular signaling. Because emitted volatile cues become available to potential competitors of the same or different species, selection for cues that are more private would likely be of greater benefit to the emitter. At the time of this study, only 2 A. tridentata chemotypes had been identified. More recent work has found an additional 6 chemotypes. Here we propose to rigorously test the ecological consequences of chemotypic variation and the processes that maintain it. Through synergistic efforts combining my expertise in field ecology and plant-insect interactions and that of the host and collaborators in ecological chemistry and molecular biology, we will forward the field of volatile-mediated plant-plant interactions.

Keywords: chemical ecology,plant communication,volatile organic compounds,entomology,volatile mediated species interactions