Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Cybersecurity platform used for scoring, predicting and remediating potential security risks (KARTOS)

Framework: Horizon Europe — Innovative Europe
Programme: European innovation ecosystems
Theme: Elevating the scalability potential of European business
Destination: Elevating the scalability potential of European business
Action type: Coordination and support actions
Countries involved: Spain
Call: Women TechEU (HORIZON-EIE-2022-SCALEUP-02, 2022)
Start date: 2023-07-01
End date: 2024-03-31
Duration (months): 9.0
Total project cost (EUR): 107142.86
EU funding (EUR): 75000.0
Participants: 1
Project status: CLOSED

ENTHEC is an early-stage deep-tech startup, pioneer in the development of Cybersecurity Solutions against cybercrime. María Rojo, Co-Founder and CEO of ENTHEC is a Computer Engineer, PhD in Telematics, with more than 12 years of experience in cybersecurity at corporates such as BBVA, Santander, Indra, or Airbus who is becoming one of the leading women in the European cybersecurity ecosystem. Constantly emerging sophisticated cyber-attacks jeopardize thousands of businesses every minute of every day. Europe must build resilience to cyber-attacks while making sure that data protection and freedom of citizens are strengthened. That is why, ENTHEC is developing KARTOS, a unique Cybersecurity Platform used for scoring, predicting and remediating security risks based on Artificial Intelligence that analyses the company's leaked information anywhere on the Internet, Deep web and Dark web. KARTOS instantly identifies vulnerabilities, active exploits, and advanced cyber-threats to help companies rigorously protect their business and strengthen their security posture from outside its IT perimeter, enabling them to see what a hacker sees thus remediating risks before a potential attack. The Cybersurveillance platforms market is dominated by US companies, which may alter their analysis by strategically affecting European companies. KARTOS is the only European solution able to defend the sovereignty of European companies in this market. Cybersurveillance platforms are a niche market within the Cybersecurity Marketplace in which ENTHEC will commercially target the European, North America, Latin America and Middle East valued at €6.000M in 2027. At that time the global cybersecurity market will be €281.000M according to Grand View Research. The successful completion of the development and commercialization of KARTOS is a great business opportunity for ENTHEC to become a European cybersecurity leader and to generate revenues of more than €20M by 2028 and more than 90 skilled jobs.

Keywords: cybersecurity,cybersurveillance,cyber attack,risk scoring,easm,drsp,platform,leak,internet,deep web,dark web,it perimeter,artificial intelligence,machine learning,cybercrime,saas
The Sleeping Embryo (MORPHEUS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Cell Biology, Development, Stem Cells and R egeneration
Panel description: For all organisms : Structure and function of the cell, cell -cell communication, embryogenesis, tissue differentiation, organogenesis, growth, development, evolution of development, organoids, stem cells, regeneration, therapeutic approaches
Countries involved: Germany
Call: ERC CONSOLIDATOR GRANTS (ERC-2021-COG, 2021)
Start date: 2023-01-01
End date: 2027-12-31
Duration (months): 60.0
Total project cost (EUR): 2000000.0
EU funding (EUR): 2000000.0
Participants: 1
Project status: SIGNED

The implantation of the blastocyst into the uterine wall is a key step of the reproductive cycle, which mediates the connection of the embryo to the maternal tissues during the early stages of pregnancy. However, in some species, including the house mouse, this process can be put on hold, while the embryo falls into a reversible state of suspended animation, known as diapause. The dormant embryos can reside in a “deep sleep” over extended periods of time (e.g. bypassing unfavourable environmental conditions), without compromising their developmental potential. Although, the maternal hormonal control of implantation and the process of transient mouse embryogenesis have been intensively studied, the embryonic diapause is still an extremely enigmatic state. Several lines of evidence, based on my preliminary data, suggest that diapause is not a stasis, but instead is a dynamic process with underlying mechanisms that can appear redundant during transient embryogenesis. Here I aim to decipher the cryptic embryo-intrinsic mechanisms of embryo dormancy, using the mouse as a model system. I will elucidate the cellular processes that coordinate and capacitate the embryo for diapause on epigenetic, transcriptional and cell signalling levels. Using interspecies chimeras and blastoids, I will extend my analysis to non-diapausing species and artificial embryo-like structures. Thus, by manipulating the flow of embryogenesis, I will uncover hidden, dormant mechanisms, safeguarding the developmental potential of the early mammalian embryo.

Keywords: embryo dormancy,diapause,blastocyst
3D spheroids derived from single cells for discovering stochastic patterns behind metastasis (3DSecret)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Pathfinder
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Portugal,Spain,Italy,United Kingdom
Call: EIC Pathfinder Open 2022 (HORIZON-EIC-2022-PATHFINDEROPEN-01, 2022)
Start date: 2023-01-01
End date: 2026-12-31
Duration (months): 48.0
Total project cost (EUR): 2591050.25
EU funding (EUR): 2591050.25
Participants: 6
Project status: SIGNED

Metastasis remains accountable for 9 out of 10 fatalities within cancer disease. However, the mechanisms governing the onset of metastasis are far from being fully understood. Notably, metastases are predominantly clonal and arise from a single cell. 3DSecret will investigate metastasis from a radically new perspective, with the overarching goal of unravelling stochastic patterns at the single-cell level with predictive and prognostic capacity. Critically, defining the hallmarks of metastasis from holistic studies of single circulating tumour cells (CTCs), thus dissecting tumour heterogeneity, has the power to revolutionise cancer treatment and diagnosis. This will pave the way for game-changing discoveries in what is one of the holy grails of modern clinical science. To achieve our goal, 3DSecret will use a set of key enabling technologies including microfluidics, nanosensors, genomics, and artificial intelligence (AI). Microfluidics will drive the isolation of single CTCs from whole blood samples of 60+ metastatic breast cancer patients. These will be grown on-chip to form 3D spheroids, thus allowing comprehensive genomic and transcriptomic studies of single-cell origin while bypassing the errors typically introduced by single-cell genome amplification. The genomic and transcriptomic data will be combined with clinical information, single-cell growth profiles and dynamic metabolomic analyses obtained by the use of nanosensors and SERS, to develop a multimodal AI analytical tool capable of identifying unknown patterns driving metastasis. The bold assumption that there could be stochastic patterns driving metastasis, cancer evolution and malignancy, makes the approach of 3DSecret exceptionally high-risk, high-gain. We are confident that such a breakthrough would lead to a major paradigm shift with significant implications in biology, physics, disruptive technologies such as AI, and critically, in the medical arena and patient care.

Keywords: microfluidics,microdroplets,sers,spheroids,metabolomics,genomics,single cells,artificial intelligence,cancer prediction
Controlling the synthesis and surface chemistry of perovskite quantum dots for the next-generation of quantum emitters (CONTROL)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Synthetic Chemistry and Materials
Panel description: New materials and new synthetic approaches, structure -properties relations, solid state chemistry, molecular architecture, organic chemistry
Countries involved: Germany
Call: ERC STARTING GRANTS (ERC-2025-STG, 2025)
Start date: 2026-02-01
End date: 2031-01-31
Duration (months): 60.0
Total project cost (EUR): 1499991.0
EU funding (EUR): 1499991.0
Participants: 1
Project status: SIGNED

Lead halide perovskite quantum dots (peQDs), with their sub-10 nm sizes, excitonic absorption, fast radiative recombination, and coherent single photon emission, are on track to fulfill the increasing demand for smaller, more efficient, and more complex optoelectronic and quantum devices. However, the ionic chemistry of these tiny emitters is fast and difficult to control, which limits their tunability, stability, processability, efficiency, and therefore their integration into future quantum devices. The aim of CONTROL is to create the first generation of tunable core-shell peQDs with fully tunable ligand shells, advancing their optical properties and surface chemistry far beyond what is currently possible. This will be achieved by obtaining a fundamental understanding of the intricate and fast chemistry, and use this knowledge to rationally redesign the synthesis of. To do so, CONTROL will develop new in situ tools, including a robotic synthesis platform with in situ spectroscopy capabilities and isothermal titration calorimetry customized to the ionic chemistry of peQDs. The mechanistic and thermodynamic insight gained with these new tools will allow us to rationally redesign the interface and surface chemistry of pQDs, take control of their epitaxial growth ontop of non-perovskite semiconductors, and control their surface chemistry. We will develop tunable core-shell peQDs, including quantum shells and infra-red emitters, with fully functional ligand shells, including conductive and polar surfaces for efficient integration into QD devices. This will open new pathways for the processability, tunability, stability and functionality of peQDs. Thus, CONTROL will not only deliver fundamental insight into the synthesis and ligands of peQDs but also make crucial, significant advancements in tuning their optical properties and surface chemistry, preparing them for integration into the next generation of efficient, stable, and tunable classic and quantum light sources.
REimagining Sonocatalytic CO2 REduction: Enhancing Organic Synthesis by Optimizing Cavitation Collapse (RESCORE)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-12-01
End date: 2027-11-30
Duration (months): 24.0
Total project cost (EUR): 193643.28
EU funding (EUR): 193643.28
Participants: 1
Project status: SIGNED

Carbon dioxide (CO2) emissions are a major environmental concern. The reduction of CO2 to valuable chemicals is crucial for closing the carbon cycle in chemical synthesis and promoting a green circular economy. Sonocatalytic processes, which use ultrasound-induced cavitation bubbles in a liquid with heterogeneous catalyst to trigger chemical reactions, hold great potential for converting CO2 into high-value organic products. However, the presence of CO2 itself hinders reaction rates by dampening the bubble collapse, limiting the primary conversion to carbon monoxide (CO). This also reduces the thermal energy transferred from the bubble to the catalyst, impeding the further reaction of CO to more reduced organic compounds. The RESCORE project aims to enhance the sonochemical reduction of CO2 to CO by increasing the liquid hydrostatic pressure to improve bubble collapse and overcome the limited CO2 conversion rates. Additionally, RESCORE seeks to identify a suitable catalyst for sonocatalytic CO2-based organic synthesis, focusing on selectivity towards desired products and enhancement of cavitation activity. This approach ensures that the catalyst benefits from higher thermal energy due to improved collapse and from increased liquid static pressure due to reactions with moles reduction. Furthermore, the overall efficiency of the sonoreactor will be assessed through process-specific output measurements. Beyond academic and research advancements, RESCORE is designed to synergistically combine the expertise at the host institution (UniTo) with that of the researcher. The fellowship will enhance the researcher's skills across a broad spectrum, providing improved career perspectives, international and interdisciplinary experience, and the opportunity to make a significant impact. Simultaneously, UniTo will gain novel research knowledge, produce valuable research output, and enhance its research capacity and global attractiveness.

Keywords: cavitation sonochemistry sonocatalysis process intensification
Mediterranean Women and Sexual Violence in the Confessional, 1600-1750 (SECS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Italy
Call: MSCA Postdoctoral Fellowships 2023 (HORIZON-MSCA-2023-PF-01, 2023)
Start date: 2024-09-01
End date: 2026-08-31
Duration (months): 24.0
Total project cost (EUR): 164950.08
EU funding (EUR): 164950.08
Participants: 1
Project status: SIGNED

'I did not accuse him because I am his enemy, but because I demand justice. He raped me and then said I should have married his nephew Lorenzo to cover this [the pregnancy] up (Maria Taboni v. Don Gauci). 'He groped me, asking for my pubic hair and a pezza [cloth] damped in menstrual blood -I was horrified!' (Margherita Caruana v. Don Fabbri). This work is inspired by all the women's and young girls' voices found in the inquisitorial records. They recounted assaults and harassment with vigor and supported one another in seeking justice. They condemned the predatorily actions and the system of impunity; their disturbing depositions convey an outstanding narrative. They show how women can be vocal, and no longer take the blame for sexual violence against them. To date, their voices have been neglected by the historiography on sexual violence and the Church. In Mediterranean cities, women and children often endured sexual violence whilst confessing to their priests. Hundreds of reports about assault and abuse were sent to the Roman Inquisitors between 1600 and 1750. However, what is remarkable is that the survivors, and their families, stood up to the perpetrators and called for punishment, irrespective of the clergymen's social standing. Despite the power dynamics at play and the gender roles, women took an active role in defending themselves, both by opening up to their families and, with other females' support, speaking up to the authorities. The Inquisition took the denunciations seriously and demanded the culprits be questioned and punished. Unlike what we might expect, mothers, husbands, fathers and friends were overwhelmingly supportive by corroborating the assaults in court. As such, women were able to circumscribe the authority of the Church and its abusive men; they did not endure abuse quietly, they spoke up and demanded justice.

Keywords: sexuality violence catholicism mediterranean
Better Bioprinting by Light-sheet Lithography (B-BRIGHTER)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Transition
Destination: Open to supporting projects in all areas of science, technology,...
Action type: EIC actions
Countries involved: Sweden,Spain,Germany,Israel
Call: EIC Transition Open 2021 (HORIZON-EIC-2021-TRANSITIONOPEN-01, 2021)
Start date: 2022-10-01
End date: 2025-03-31
Duration (months): 30.0
Total project cost (EUR): 2093332.5
EU funding (EUR): 2093331.0
Participants: 5
Project status: SIGNED

Bioprinting is considered the most promising method to produce functional engineered tissues with physiological properties. Successful tissue engineering will open research avenues for drug testing and therapeutic and will therefore raise much interest not only in the academia, but also pharma and clinical sectors. Current bioprinting methods are limited by combinations of insufficient speed, spatial resolution and cell viability. Since these technologies often suffer from poor spatial resolution and inability to control biomechanical properties, they fail to mimic the heterogeneous nature of native tissues. B-BRIGHTER aims to develop a novel bioprinting technology able to produce engineered tissues with high spatial resolution at high printing speed using an original top-down lithography approach. In contrast with current bottom up, layer-by-layer bioprinting methods, B-BRIGHTER aims at ultra high-speed digital light-sheet illumination strategy to selectively photo-crosslink cell-laden hydrogels mimicking specific tissues, in confined voxels and produce three-dimensional complex geometries. Previous advances from the BRIGHTER project will be extended by building complex bioengineered skin, cornea and gut tissue models, all of which represent pioneering examples for bioengineering, and its application for cell therapy, drug discovery and toxicology. Together with the work on patterning technology, bioink and application, a basis will be established for formulating a valid business case for a bioprinting product. The work on exploitation activities will ultimately result in a go-no go decision for the industrialisation of a bioprinting product and a commercial path forward. Ultimately, the goal of the B-BRIGHTER project is to provide a radically new bioprinting technology to boost the performance of various engineered tissues which in turn will promote improved healthcare opportunities, as well as business and employment advances in the European Union and beyond.

Keywords: bioprinting,bioink,laser light sheet,light sheet patterning,light sheet microscopy
Enhancing Inclusivity in Higher Education through Universal Design for Learning (EIHEUDL)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Attracting and mobilising the best talents
Destination: Attracting and mobilising the best talents
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Portugal
Call: ERA Fellowships (HORIZON-WIDERA-2024-TALENTS-02, 2024)
Start date: 2025-12-01
End date: 2027-11-30
Duration (months): 24.0
Total project cost (EUR): 191343.12
EU funding (EUR): 191343.12
Participants: 1
Project status: SIGNED

This research proposal aims to investigate the effectiveness of Universal Design for Learning (UDL) in enhancing inclusivity in higher education. Inclusivity ensures that all students, regardless of their backgrounds, have equitable access to learning opportunities and can fully participate in the academic community. UDL is an educational framework that promotes flexible learning environments to accommodate individual learning differences. Furthermore, the study will employ a mixed-methods approach, combining quantitative surveys and academic records analysis with qualitative interviews and focus groups. The sample includes students, educators, and administrators from selected higher education institutions in Portugal and the UK. Moreover, the research objectives include assessing the current level of inclusivity in higher education, evaluating the implementation of UDL principles, identifying barriers to successful adoption, and measuring the impact of UDL on student engagement, retention, and academic performance. Furthermore, expected outcomes include a detailed assessment of inclusivity, an evaluation of UDL's effectiveness, identification of implementation barriers, and evidence-based recommendations for enhancing inclusivity through UDL. This research will provide valuable insights for educators and policymakers, contributing to the development of more inclusive learning environments and supporting the academic success of all students.

Keywords: inclusivity,higher education,universal design for learning udl,educational framework,flexible learning environments,mixed methods approach,student engagement,learners differences
Breakthrough Generative AI to Redefine Content Creation and Monetisation (Multimarkts)

Framework: Horizon Europe — Innovative Europe
Programme: The European Innovation Council (EIC)
Theme: EIC Accelerator
Destination: Other destinations
Action type: EIC actions
Countries involved: Spain
Call: EIC Accelerator 2024 - Short application (HORIZON-EIC-2024-ACCELERATOR-01, 2024)
Duration (months): 24.0
Total project cost (EUR): 2497950.0
EU funding (EUR): 2497950.0
Participants: 1
Project status: SIGNED

Multimarkts is a groundbreaking generative AI platform developed by NextChance Tech, S.L. in Spain, led by visionary Nicolás Luca de Tena. The platform aims to revolutionise content creation and monetisation by integrating advanced AI technologies, allowing creators to produce high-quality, engaging promotional content effortlessly. Addressing inefficiencies in the rapidly growing content creator marketing industry, which is expected to reach $250 billion by 2032 with a CAGR of 33%, and the generative AI market projected to become a $1.3 trillion industry with a CAGR of 42%, Multimarkts fills the gap for flexible, realistic audiovisual content with seamless brand integration. Multimarkts introduces true digital twins of content creators, drastically reducing the time and effort required for content production. The platform’s innovative AI, leveraging Vision Transformer and Stable Diffusion XL models, generates high-fidelity content and integrates direct product purchase options, enhancing monetisation potential. It offers an intuitive web app for content management, is applicable across various industries, and significantly cuts CO2 emissions by reducing the need for physical samples, promoting sustainability. With interest from 585 brands, including Amazon and Adidas, and over 100 content creators, Multimarkts demonstrates strong market demand. The team comprises 58 professionals with expertise in AI development, software engineering, digital marketing, and business strategy, ensuring robust support for the platform’s growth. Seeking €2.5 million in EIC grant funding and €5 million in equity investment, Multimarkts aims to develop video-based content capabilities and expand internationally. The platform's advanced AI capabilities push the boundaries of current generative AI, positioning it as a leader in the digital content industry. By addressing content creation and monetisation inefficiencies, Multimarkts is set to drive growth and innovation on a global scale.

Keywords: generative ai,digital twins,content creation,vision transformer,stable diffusion,e commerce,influencer marketing,digital automation,advance ai algorithms,marketing technology,martech,