Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Demonstration of superradiance in a semiconductor nanostructure (SUPERRAD)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: European Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: France
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2011-03-01
End date: 2014-02-28
Duration (months): 36.0
Total project cost (EUR): 45000.0
EU funding (EUR): 45000.0
Participants: 1
Project status: CLOSED

Superradiance (SR) refers to spontaneous quantum phase transition, in which a self-organized build up of coherent radiation within an ensemble of quasi-degenerate emitters occurs. It was first noted by Dicke back in 1954 that, with increasing their density, the collection of N radiators starts to emit much faster and stronger comparing to spontaneous emission of individuals. More precisely, when packing up N identical emitters into the space comparable with a cube of the radiation wavelength, instead of observing isotropic and exponentially decaying emission, one produces a fierce, directional radiation burst, having a lagged peak intensity scaling like N2 and N-times reduced duration with respect to the spontaneous emission. Apart from the fundamental aspect, the research for SR is motivated by the prospects in producing ultra-short, intense, coherent light pulses - in alternative to lasers. The prerequisite for creating a SR emission is a spectral uniformity of participating transitions. For that reason SR was first successfully observed in atomic and molecular ensembles. As concerns semiconductor nanostructures, nowadays widely used in optoelectronics, the evidence for SR has never been provided, as the SR effect is obscured by the spectral inhomogeneous broadening in a semiconductor matrix. The goal of this project is to achieve the first proof for SR within an ensemble of individual emitters embedded in a nanostructured semiconductor. To this aim, we will focus our efforts on donor-bound-excitons (D0X), which are excitons (Coulomb correlated electron-hole pairs) localized on donor impurities in a semiconductor, for instance Si replacing Ga atoms in a GaAs lattice. D0Xs are characterized by small, sub-meV, inhomogeneous broadening, large oscillator strength and a few hundreds ps lifetime - all acting in favor for inducing SR. Our approach will employ methods of both linear (PL, streak camera) and nonlinear (up-conversion) time-resolved optical spectroscopy.

Keywords: physics of semiconductors,solid state physics,spectroscopy,applied optics,optical and dielectric properties,experimental physics
Computation with real Lie Groups (CORELG)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-10-01
End date: 2013-09-30
Duration (months): 24.0
Total project cost (EUR): 180912.0
EU funding (EUR): 180912.0
Participants: 1
Project status: CLOSED

Group theory is the mathematical discipline that deals with the systematic study of symmetry. Lie groups are used to describe some of the most complex forms of symmetry. Therefore they find many applications in various diverse areas such as physics and geometry. Since the invention of the computer, it has been used as a tool in the study of group theory and, in particular, Lie groups. This has led to a new research area, called Computational Lie Theory. The main focus in this area has been on complex Lie groups. However, it would be of great interest to use the computer to study real Lie groups because of the abundance of applications that these groups have in physics and differential geometry. It is the aim of the project "Computation with Real Lie Groups" (CoReLG) to start such a development in Europe. In the U.S.A. a similar project has been set up, called the ATLAS project. In 2007 this project had a huge success, widely reported in the international press, when the so-called Kazhdan-Lusztig-Vogan polynomials were determined for the real Lie group of type E8. The project CoReLG aims at starting a similar research project in Europe. However, the research goals of the CoReLG project are genuinely different from those of the ATLAS project. The main objective will be to develop algorithms for one of the main problems regarding Lie groups: obtaining their orbits. As this problem is intractable in general, we focus on a special class of Lie groups, namely real theta-groups, which contain many instances of interest. Furthermore, the project aims at implementing these algorithms as a software package for a European public domain computer algebra system, such as GAP. A third goal of the proposed project is to develop applications of the algorithms in differential geometry and theoretical physics. This will be carried out in collaboration with several European differential geometers and physicists.

Keywords: mathematics,computational mathematics,lie theory,orbits classification,differential geometry
Rights and Liberties in a Comparative Perspective: A Cross National Analysis of Discrimination Against Sexual Minorities (CIVLIBSID)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Re-integration Grants
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Israel
Call:  (FP7-PEOPLE-2010-RG, 2010)
Start date: 2011-04-01
End date: 2015-03-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

This interdisciplinary research project will attempt to develop a new theoretical paradigm for the understanding of rights and liberties in a comparative perspective, with a particular emphasis on the rights and liberties of sexual minorities. The innovative aspects of the research are in its attempt to form a new theoretical framework, the collection of original data and the use of a combination of cutting edge methodological approaches to empirically test the theory. The proposed project aims to contribute in several ways to the discipline of political science, the study of law and public law, sociology and to policy studies. This research project’s main goal is to explain the creation of rights and liberties in a comparative perspective by analyzing the systematic effects of variables running the gamut from the origins of the legal system and the nation’s level of globalization to modernization and political inclusion in the polity. In terms of productivity, the ultimate goal is to produce a book manuscript and a series of journal articles based on the novel theory, data and methods. In addition, an international conference will be organized on the topic, where researchers from Europe, Israel and elsewhere will present their work and discuss substantive and methodological issues. Lastly, a student exchange program with institutions in Europe and the United States will be established and additional grant applications will be based on the products of this project.

Keywords: social sciences,civil rights and liberties,comparative public law,comparative constitutionalism,sexual minorities
VIRTUAL OPTIMIZATION CFD PLATFORM ALLOWING FAN NOISE REDUCTION (VOCAL-FAN)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Clean Sky
Action type: Article 171 of the Treaty
Partnership: CLEAN-SKY (Art-185)
Countries involved: Italy
Call:  (SP1-JTI-CS-2010-03, 2010)
Start date: 2011-02-01
End date: 2013-03-31
Duration (months): 26.0
Total project cost (EUR): 199115.0
EU funding (EUR): 149335.0
Participants: 1
Project status: CLOSED

The activities encompassed by this proposal consist in the development and exploitation of a methodological approach, suitable for the optimization of the fan and duct geometries in an electrical machine, with the aim to improve both the aerodynamic and acoustical performance of the system. The global activity will consist in a first baseline CFD calculation, a screening of different fan designs and finally an optimized fan design in terms of fluid dynamic performance and noise reduction. The advanced character of the forecast approach is linked to the following aspects: a) the implementation of the most advanced algorithms and procedures for CFD simulation; b) the exploitation of Design Of Experiment algorithms during the initial screening phase and for the preliminary selection of the most relevant parameters; c) the development of a simulation process flow controlled by Multi-Objective Optimization algorithms, which will allow a complete exploration of the influence of the parameters affecting the system performances, and Response Surfaces algorithms, which will allow the interpolation of the database of virtual (and experimental) data and the definition of an expert system; d) the ranking of the analyzed models, with respect to their key performances, and the selection of the optimal candidate(s), considering the multiple selected objectives, by means of the mostly advanced Multi Criteria Decision methods. Thus the present proposal is meant to develop a fully integrated software platform based on the most advanced functionalities of the following tools: 1) ANSYS-CFX, whose functionalities and capabilities are worldwide recognized for their completeness and robustness; 2) modeFRONTIER, one of the most advanced software tool for the optimization and the process integration available on the market.

Keywords: aerospace,cae,cfd,acoustics,optimization,noise reduction,cooling fan
Multiplexed protein and kinase activity detection assays in complex media using impedance/capacitance (MPKADAIC)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Incoming Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IIF, 2010)
Start date: 2011-11-01
End date: 2013-10-31
Duration (months): 24.0
Total project cost (EUR): 280680.0
EU funding (EUR): 280680.0
Participants: 1
Project status: CLOSED

The detection and quantification of protein biomarkers in biological samples lies central to proteomics, drug design, disease prognosis and therapeutic development. The generation of viable protein microarrays is, though, challenging. The first protein microarrays were built on antibodies. Unfortunately antibodies do not function well in the microarray format, because typically only a small fraction (20%) specifically recognizes the target protein. Current antibody based optical assays are commonly based on sandwich assays in which antigen binding to the immobilised antibody is detected through the use of a secondary, labeled, antibody. Though sensitive, this method is laborious and often requires a specifically-labelled secondary antibody for every antigen of interest. Labelling protocols are potentially perturbative, can also be time consuming and may lead to high background signals. Alternative protein receptive molecules are thus of considerable interest. In recent years, the host group has developed, with a team in Leeds, optical and electrical assays based on the use of peptide aptamers (highly specific protein receptors built into the surface of robust scaffold proteins). These can be immobilized with controlled surface orientation on a variety of surfaces. The aim of this proposal is to utilize this experience in developing highly sensitive electrical protein assays using capacitance and impedance (AC, DC, Faradaic and Non Faradaic). Through appropriate surface chemical methods such assays will be operable in complex fluid such as cell lysates and blood. Being electrical they are also readily multiplexed at comparatively low cost, enabling simultaneous detection of multiple targets. The linear range potentially accessible within such arrays is considerable, as is the potential clinical benefit.

Keywords: analytical chemistry,measurement technology,electrochemistry,protein detection assays,impedance,capacitance,peptide aptamer,biosensor,kinase
The star-formation histories and dark-matter content of faint dwarf elliptical galaxies (HOLYDWARFS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Belgium
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-06-15
End date: 2013-06-14
Duration (months): 24.0
Total project cost (EUR): 163800.0
EU funding (EUR): 163800.0
Participants: 1
Project status: CLOSED

In a cosmological context the dwarf galaxies (stellar masses M < 10^9 Msun) are crucially important because they hold keys to solve some of the most important questions in current extragalactic astronomy: - What are the effects of the environment on the evolution of galaxies? Because of their low masses, dwarfs are ideal targets to study environmental processes such as ram-pressure stripping and galaxy harassment. - What are the mechanisms controling star formation? Due to their shallow gravitational potential wells, dwarf galaxies are very sensitive to processes like supernova feedback. This feedback heats and disperses the gas, affecting the star-formation efficiency. In combination with environmental effects, it may even cause the gas to be lost from the host galaxy. - What are the properties of the dark matter? Dwarf galaxies appear to be among the most dark matter dominated objects in the nearby universe, making them prime objects to study the properties and spatial distribution of this elusive ingredient of the universe. While the dwarf galaxies below 10^7 Msun appear to be dark matter dominated, those more massive than 10^9 Msun are not. Our goal is to investigate the terra incognita between these two regimes, i.e. galaxies with stellar masses around 10^8 solar masses. Trough stellar population analysis, dynamical modeling and numerical simulations we will be able to shed light on the controlling mechanism of star formation and the role of the dark matter. We will study the dwarf dark-matter halo occupancy and investigate the physical processes that cause the photometric scaling relations to change slope around stellar mass M~10^8 solar masses. This project calls for a multidisciplinary approach, combining the host institute's expertise in dynamical modeling and simulations with the applicant's expertise in stellar populations analysis.

Keywords: astronomy,cosmology
Synthetic kinesin analogues: A transition metal complex that can walk (METALWALKER)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Intra-European Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2010-IEF, 2010)
Start date: 2011-03-01
End date: 2013-02-28
Duration (months): 24.0
Total project cost (EUR): 200549.6
EU funding (EUR): 200549.6
Participants: 1
Project status: CLOSED

The goal of the research project proposed is to design, synthesise, operate and fully characterize a wholly synthetic molecular machine mimicking the mechanical action of the kinesin motor protein, namely unidirectional, hand-over-hand (also known as “passing leg”), mechanically processive motion to propel a molecule along a pre-defined molecular “track”. To accomplish this purpose, two sets of kinetically stable binding units must be present on the walker unit. These two units must have orthogonal binding requirements and the relative binding affinities of one of the units within the binding points along the track must be switchable by a stimulus that does not affect the other binding unit. To mimic the kinesin action in a synthetic molecular system, metal-binding events of the motor molecule along the functionalized track are exploited to control the thermodynamics and kinetics of biased Brownian motion in a functional molecular system. In concrete, the binding units of the walker contain two metallic centres, a palladium(II) complex and a platinum(II) complex, which can undergo a proton-mediated ligand exchange based on two orthogonal mechanisms, because while the exchange of the palladium(II) complexes is achieved thermally, the one of the platinum(II) centres is photochemical. This system can be considered a part of the state-of-the-art interest to develop wholly artificial chemical systems which display the propety of sequential processivity. The novelty is that the proposed system is based on a pH-dependant ligand exchange on Pd(II) and Pt(II) complexes, which is expected to result in a highly directional movement under termodynamic control.

Keywords: physical sciences,chemistry,macromolecular chemistry,inorganic chemistry,organic chemistry
GENOMIC AND TRANSCRIPTIONAL ANALYSIS OF GLIOBLASTOMA MICROENVIRONMENTAL CELLULAR SUBSETS USING ANTIBODY MICROARRAYS (CROSSTALK IN GBMS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: International Outgoing Fellowships
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Italy
Call:  (FP7-PEOPLE-2010-IOF, 2010)
Start date: 2011-10-01
End date: 2014-09-30
Duration (months): 36.0
Total project cost (EUR): 230084.8
EU funding (EUR): 230084.8
Participants: 1
Project status: CLOSED

The applicant is an experienced researcher with the objective of completing comprehensive training in translational research on Glioblastoma Multiforme (GBM), one of the most common malignant and lethal primary brain tumor of adults, with the final aim of disposing of personalized therapeutic protocols for GBM and cancer patients. The project is based on the finding that human tumors, particularly GBMs, are composed of a mixture of cancer, immune, stromal and vascular cells. The non-cancerous cellular components of the tumor microenvironment appear to play a critical role in tumor development and progression. At UCLA (Los Angeles, U.S.A.), the Mischel Lab has developed the DNA Encoded Antibody Library (DEAL) microarray, to sort specific cellular subtypes from solid tumor samples. The selective capture of tumor cells, lymphocytes, microglia and vascular endothelial cells, directly from GBM biopsy samples, will be obtained by DEAL technology. Genomic and transcriptional analysis will be performed on DEAL sorted cellular subtypes in order to identify novel molecular targets for therapeutic intervention. Genomic and transcriptional findings will be validated with functional assays in model systems: oncogene overexpression, gene silencing and pharmacological inhibition will be applied in order to identify the factors that inhibit the growth and survival of GBMs. In the first phase of the fellowship, at UCLA, the applicant will be utilizing cutting edge nanotechnology and resources that will provide her with outstanding interdisciplinary skills and competences. The applicant will then have the professional maturity to transfer her novel knowledge to the University of Verona (Italy), enriching the scientific excellence of Europe and bridging a new set of collaborations between Italy and the U.S.A.

Keywords: glioblastoma,microenvironment,tumor stroma interaction,microarrays,genomic alterations,transcription
Piezo Power Supply Module for Piezo Actuator Bench (PPSMPAB)

Framework: FP7 — Cooperation
Programme: Joint Technology Initiatives (Annex IV-SP1)
Theme: Public-private partnerships
Destination: Clean Sky
Action type: Article 171 of the Treaty
Partnership: CLEAN-SKY (Art-185)
Countries involved: France
Call:  (SP1-JTI-CS-2010-03, 2010)
Start date: 2011-05-01
End date: 2014-04-30
Duration (months): 36.0
Total project cost (EUR): 427350.0
EU funding (EUR): 320512.5
Participants: 2
Project status: CLOSED

The Green Rotorcraft research Consortium of Clean Sky (CS-GRC) requests the development of a Piezo Power Supply module (PPS) and the associated Man Machine Interface (MMI). CEDRAT (coordinator, SME) and UJF-G2ELAB (partner, lab from Grenoble Joseph Fourier University) forms a consortium using their shared experience on piezoelectric actuators and high efficiency high power supplies to meet the GRC request by the PPSMPAB project. The PPSMPAB project aims at developing 2 PPS offering the highest required power (16kVA) with a high efficiency, for driving piezo actuators, accounting for further helicopter applications. The proposed development splits the need in 3 main items: The preferred DC-DC converter providing the DC sources would be an isolated full bridge resonant converter, with adjustable bus DC voltage. The DC-AC 2-channels switching amplifier will provide the 2x8kVA power with adjustable output voltage range. The preferred approach is today a full bridge offering bipolar output. For highest targeted voltages, multilevel amplifiers will be considered. The MMI will combine a digital platform and associate software, preferred one being Labview Real-Time RIO. For the PPSMPAB project, CEDRAT and UJF-G2ELAB propose the following WBS: WP1 - Management: CEDRAT will perform a technical, contractual and financial administration of the project and will guarantee the objectives and deadline complying. WP2 - Design concept & architecture: UJF-G2ELAB will analyse electronic architectures (several being identified in the proposal) and technologies (MOSFET vs IGBT) and will present the results in form of trade-off, allowing the GRC Consortium to select the one to develop. WP3 - Detailed design & manufacturing: CEDRAT will perform the PPSM detailed design and manufacture two prototypes. WP4 - System validation tests: CEDRAT will perform requested tests on PAB and EDS benches and provide both support and the final report with recommendations on PPS modules.

Keywords: piezo power supply module actuator helicopter green rotorcraft jti-cs-2010-3-grc-03-004