Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Bimetallic catalyst knowledge-based development for energy applications (BIKE)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: Germany,Spain,Australia,Italy,Italy,Spain,Italy,Italy,Norway,Bulgaria,Netherlands,Denmark,United Kingdom,United Kingdom
Call: Innovative Training Networks (H2020-MSCA-ITN-2018, 2018)
Start date: 2019-04-01
End date: 2023-12-31
Duration (months): 57.0
Total project cost (EUR): 3722680.8
EU funding (EUR): 3722680.8
Participants: 14
Project status: SIGNED

BIKE (BImetallic catalysts Knowledge-based development for Energy applications) is a network for training of T-shaped young promising scientists (early stage researchers, ESRs), who will develop and apply, by an innovative “holistic” approach, the next generation of bimetallic catalysts for energy management, in particular for blue and green hydrogen production processes. BIKE next generation bimetallic catalysts will exhibit superior performance under realistic conditions thanks to the combination of state-of-the-art tools (predictive modelling, advanced characterization, knowledge based design and novel preparation of catalysts, and explorative testing) in a single methodology to fully exploit their added value in a synergistic way. The explosive growth of blue and green hydrogen production in recent years, due to its importance in environment and energy fields, has created a strong need of qualified personnel both in the private industry: a) manufacturing; b) R&D; c) management, and in the public sector i.e. (i) academia, (ii) research centres, including (iii) management. The goal of the BIKE ITN is to address this need by providing a team of 14 qualified ESRs with a comprehensive and application-oriented knowledge of the H2-field, able to span from preparation to characterization, modelling, industrial applications, and marketing of H2-related catalyst materials, and to interact with all the stakeholders working in the field. This goal is achieved by devising a cross sector, application-oriented, multi-disciplinary and synergic intense training plan at 12 European research centres leaders in the Fuel Cells and Hydrogen (FCH) field, in academia and public research institutions (9) and industry (3), integrated with soft skills components, exchange meetings, workshops, schools, courses as appropriate to pursue the BIKE's goal. Industrial members will strongly contribute to cross sector training and validation in industrial environment of BIKE bimetallic catalysts.

Keywords: bimetallic heterogeneous catalysts,steam reforming,aqueous phase reforming,water electrolysis,materials and process characterization
Making Humans: Human Dignity in Nineteenth-Century France (HuDig19)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Reintegration panel
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: France
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-10-01
End date: 2023-09-30
Duration (months): 24.0
Total project cost (EUR): 196707.84
EU funding (EUR): 196707.84
Participants: 1
Project status: SIGNED

Human dignity refers to the intrinsic worthiness of the human being, which renders all individuals equal bearers of rights. It is a shared value of the European Member States and the cornerstone of the EU Charter of Fundamental Rights. Modern scholarship has relied on an uncontested paradigm: the recognition of the intrinsic worthiness of the human being necessarily entails social justice and the equality of all individuals. This approach is nonetheless unsuitable for examining human dignity in the nineteenth century, a time period that has been insufficiently explored. HuDig19 focuses on the case of France and reveals fascinating discoveries. Human dignity was defined as a sentiment, a conception that does not bear any historical precedents. Human dignity was deployed to humanize certain people while downgrading the humanity of others. Human dignity was also used to conceal inequalities and to justify injustices. To explain those startling findings, HuDig19 adopts a novel critical theory approach and explores untapped nineteenth-century sources. The idea of human dignity has never been studied in such an archival and critical ways. HuDig19 focuses on the following research objectives: a) To unveil why human dignity was conceived as a sentiment b) to explain its emotional regime c) to examine whether human dignity was used to justify inequalities d) to reveal how it was used to strip women of their citizenship and e) to update our contemporary conception of human dignity. HuDig19 open new interdisciplinary perspectives for the studies of a value that defines our democracies. HuDig19 is carried out by Prof. Antonio Pele, who has developed strong expertise on human dignity. The primary supervisor, Prof. Bernard E. Harcourt, is a leading scholar in critical theory. The co-supervisor, Prof. Arnaud Esquerre is a renowned scholar in historical sociology. HuDig19 is implemented in the remarkable infrastructure of the Ecole des Hautes Etudes en Sciences Sociales in Paris.

Keywords: critical theory,emotions,france,human dignity,nineteeth century,rights,women
5G Enablers for Network and System Security and Resilience (5G-ENSURE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Theme: Future Internet: Software, hardware, Infrastructures, technologies and services
Action type: Research and Innovation actions
Countries involved: Spain,Italy,Finland,Sweden,France,France,France,France,France,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Advanced 5G Network Infrastructure for the Future Internet (H2020-ICT-2014-2, 2014)
Start date: 2015-11-01
End date: 2017-10-31
Duration (months): 24.0
Total project cost (EUR): 7584046.25
EU funding (EUR): 7584046.25
Participants: 17
Project status: CLOSED

5G-ENSURE will define and deliver a 5G Security Architecture, shared and agreed by the various 5G stakeholders. It will specify, develop and release an initial set of useful and usable security enablers for 5G. These enablers will be selected for their relevance in addressing some of the foremost security concerns in order to generate the trust and confidence necessary for 5G to be widely adopted and to deliver its promises through innovative business applications. The 5G-ENSURE project will also initiate a 5G Security testbed vision and initial set-up in which the security enablers will be made available. Moreover, the potential of the developed 5G Security enablers will be showcased and demonstrated in the context of carefully selected 5G security use cases (e.g. use cases related to cybersecurity and aerospace). Coupled with this, 5G-ENSURE will be closely linked to the overall 5G PPP programme through active participation in common activities and fora. Specifically, 5G-ENSURE will be the project that creates and animates a dedicated 5G PPP Security Working Group to coordinate the various security-related activities. 5G-ENSURE is led by a strong consortium bringing together the appropriate and complementary skills, including standards involvement and deep telco understanding, along with an extensive network of interested parties, and have a proven track-record in coordination. 5G-ENSURE will avail itself of the support of a group of international opinion leaders.

Keywords: network and systems security,resilience,privacy,trust,network monitoring,virtualization,network management,risk assessment and mitigation
Infrared sensing made visible: Combining infrared light sources and upconversion sensors for improved sensitivity in medical applications and gas analysis (Mid-TECH)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Germany,Ireland,Germany,Spain,Sweden,United Kingdom,Denmark,Denmark,Denmark
Call: Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) (H2020-MSCA-ITN-2014, 2014)
Start date: 2015-01-01
End date: 2018-12-31
Duration (months): 48.0
Total project cost (EUR): 4001129.28
EU funding (EUR): 4001129.2800000003
Participants: 14
Project status: CLOSED

The mid-infrared (mid-IR) wavelength range is an emerging and important new topic for frontier research. Its general importance relates to a multitude of mid-IR industrial and biomedical sensor applications. Chemical finger prints of most complex molecules such as those found in food, tissue or catalytic compounds all have vibrational spectra in the mid-IR, thus identifiable through mid-IR spectroscopy. Incidentally also the fundamental absorption bands of gas molecules are located in the mid-IR enabling novel instrumentation for mid-IR gas spectroscopy at small concentrations relevant for applications like, “leak-tests” or remote sensing of greenhouse gases. The main obstacle for the exploitation of the mid-IR optical window has been a historical lack of efficient mid-IR excitation light sources and sensitive mid-IR detectors/imaging. In mid-TECH we have gathered the best European academic and industrial partners to show that in a combined effort both technological short comings can be overcome paving the way for novel instrumentation for industry and society. Key elements are novel semiconductor based Quantum Cascade Lasers (QCLs), rugged mid-IR Optical Parametrical Oscillators combined with novel, record “low noise” mid-IR upconversion detection and imaging. These two building blocks will be implemented for cancer diagnostics, for combustion analysis and absorption/DIAL spectroscopy. Since we are combining frontier research within different mid-IR areas we do not at present have the necessary skilled researchers knowing the combined mid-IR enabling components. It is a main goal of mid-TECH to train 15 ESRs to an outstanding level where they subsequently to their study can act as Europe’s new cross-sectorial technical experts in mid-IR technology at one hand and at the same time fill in a much needed link between academia and industry. This is realized through entrepreneurial courses and secondments between the mid-TECH partners.

Keywords: mid infrared,upconversion,supercontinuum,dial,hyperspectral imaging,cancer research,medical imaging,gas analysis
Molecular mechanisms of induced protection against sepsis by DNA damage responses (iPROTECTION)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Portugal
Call: ERC Consolidator Grant (ERC-2014-CoG, 2014)
Start date: 2015-10-01
End date: 2021-03-31
Duration (months): 66.0
Total project cost (EUR): 1985375.0
EU funding (EUR): 1985375.0
Participants: 1
Project status: CLOSED

Severe sepsis remains a poorly understood systemic inflammatory condition with high mortality rates and limited therapeutic options outside of infection control and organ support measures. Based on our recent discovery that anthracycline drugs prevent organ failure without affecting the bacterial burden in a model of severe sepsis, we propose that strategies aimed at target organ protection have extraordinary potential for the treatment of sepsis and possibly for other inflammation-driven conditions. However, the mechanisms of organ protection and disease tolerance are either unknown or poorly characterized. The central goal of the current proposal is to identify and characterize novel cytoprotective mechanisms, with a focus on DNA damage response dependent protection activated by anthracyclines as a window into stress-induced genetic programs conferring disease tolerance. To that end, we will carry out a combination of candidate and unbiased approaches for the in vivo identification of ATM-dependent and independent mechanisms of tissue protection. We will validate the leading candidates through adenovirus-mediated delivery of constructs for overexpression (gain-of-function) or shRNA for gene silencing (loss-of-function) to the lung, based on our recent finding that rescuing this organ is essential and perhaps sufficient in anthracycline-induced protection against severe sepsis. The candidates showing the most promise will be characterized using a combination of in vitro and in vivo genetic, biochemical, cell biological and physiological methods. The results arising from the current proposal are likely not only to inspire the design of transformative therapies for sepsis but also to open a completely new field of opportunity to molecularly understand core surveillance mechanisms of basic cellular processes with a critical role in the homeostasis of organ function and whose activation can ultimately promote quality of life during aging and increase lifespan.

Keywords: sepsis,anthracyclines,dna damage responses,disease tolerance,lung,cytoprotection
Innovative Actuators for empowering smart pipeline infrastructures towards secure water, gas and heating supply (ACT4INFRA)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: SME instrument
Countries involved: Germany
Call: Critical infrastructure protection topic 7: SME instrument topic: “Protection of Urban soft targets and urban critical infrastructures” (H2020-SMEINST-1-2014, 2014)
Start date: 2015-07-01
End date: 2015-12-31
Duration (months): 6.0
Total project cost (EUR): 71429.0
EU funding (EUR): 50000.0
Participants: 1
Project status: CLOSED

In the project ACT4INFRA a novel technology for an automated and remote controlled valves in public networks, such as water, gas or district heating, shall be commercialized on mass market scale. The technology addresses the public urban piping systems, e.g. for water, gas or district heating, which are today almost fully mechanical, manually controlled and extremely vulnerable with respect to criminal interventions or terroristic attacks. The ACT4INFRA technology has been developed within the past years by the German SME company 3S-Antriebe GmbH. Core of the innovation is a patented rotationally locked support plate (‘System Berliner Kappe’), which enables retrofitting of automated actuators in already existing valves without flanging and without a manhole. Additionally, the actuators have been optimized for low energy consumption and can operate fully decentralized powered by batteries. The entire system is controlled by safety-approved wireless communication systems, fulfilling the strong requirements of the German Federal Office for Information Security (BSI). No construction work for cabling and no switching cabinet is required. The ACT4INFRA system is a key enabling technology for low cost retrofitting in order to protect vital urban infrastructure against unauthorized access. This allows to implement smart and secure networks of piping systems. Within ACT4INFRA, 3S strives for systematic market development, distribution strategy and effective international commercialization of this technology on abroad, international mass markets. Thus, Phase 1 starts with a feasibility study , where market structure, customer needs, boundary conditions in different countries and geographical areas, cost structures, economy of scale and production strategies are analyzed. An updated business plan with these results will be prepared.

Keywords: critical infrastructure,pipe network,valve actuator,encrypted automation,smart infrastructure,water,heat,energy
TORrefying wood with Ethanol as a Renewable Output: large-scale demonstration (Torero)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Alternative fuels and mobile energy sources
Action type: Innovation actions
Countries involved: Austria,Sweden,Belgium,Belgium,Belgium,Netherlands
Call: Demonstration of the most promising advanced biofuel pathways (H2020-LCE-2016-RES-IA, 2016)
Start date: 2017-05-01
End date: 2024-05-31
Duration (months): 85.0
Total project cost (EUR): 18090177.5
EU funding (EUR): 11472915.63
Participants: 7
Project status: SUSPENDED

Torero will demonstrate a cost-, resource-, and energy-efficient technology concept for producing bioethanol from a wood waste feedstock, fully integrated in a large-scale, industrially functional steel mill: - Wood waste is converted to biocoal by torrefaction - Biocoal replaces fossil powdered coal in a steel mill blast furnace - Carbon monoxide in blast furnace exhaust fumes is microbially fermented to bioethanol - Material and energy loops of the process are closed to a very large degree Every steel mill that implements this concept will be able to produce at least 80 million litres of bioethanol per year. This project creates a value chain for wood waste, which currently has no attractive applications. The technology concept is open ended: in the future, stakeholders may replicate the concept with other feedstocks and for producing other types of fuels. The business case the Torero project will produce a competitive process for non-food feedstock bioethanol production. Compared with the current first generation production based cellulosic bio-ethanol solution the Torero innovation the OPEX of Torero is 1/3 lower with a same CAPEX. This will allow scale up of torrefaction technology when successfully demonstrated. Most importantly, together with sister project Steelanol, Torero will be the only H2020 project to demonstrate a biofuel production process that is integrated in an existing, fully functional large-scale industrial facility. All other H2020 solutions will need to be newly built if they ever reach full industrial scale. Torero is add-on technology that can be used to upgrade existing facilities of the steel sector, an industry that is actively scouting for technological solutions to make its production processes more sustainable. The consortium consist of full value chain, industry ArcelorMittal and Van Gansewinkel, two expert research organisations Joanneum Research and Chalmers Technical University and torrefaction technology supplier Torr-Coal.

Keywords: torrefied wood biomass feedstock for bioethanol
A regenerative medicine approach in diabetes. (EYELETS)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Prevention, Diagnosis and Treatment of Human Diseases
Panel description: Medical technologies and tools for prevention, diagnosis and treatment of human diseases, therapeutic approaches and interventions, pharmacology, preventative medicine, epidemiology and public health, digital medicine
Countries involved: Sweden
Call: ERC Advanced Grant (ERC-2018-ADG, 2018)
Start date: 2020-01-01
End date: 2024-12-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: SIGNED

Pancreatic islet transplantation is essential for diabetes treatment. Outcome varies due to transplantation site, quality of islets and the fact that transplanted islets are affected by the same challenges as in situ islets. Tailor-making islets for transplantation by tissue engineering combined with a more favorable transplantation site that allows for both monitoring and local modulation of islet cells is thus instrumental. We have established the anterior chamber of the eye (ACE) as a favorable environment for long term survival of islet grafts and the cornea as a natural body window for non-invasive, longitudinal optical monitoring of islet function. ACE engrafted islets are able to maintain blood glucose homeostasis in diabetic animals. In addition to studies in non-human primates we are performing human clinical trials, the first patient already being transplanted. Tissue engineering of native islets is technically difficult. We will therefore apply genetically engineered islet organoids. This allows us to generate i) standardized material optimized for transplantation, function and survival, as well as ii) islet organoids suitable for monitoring (sensor islet organoids) and treating (metabolic islet organoids) insulin-dependent diabetes. We hypothesize that genetically engineered islet organoids transplanted to the ACE are superior to native pancreatic islets to monitor and treat insulin-dependent diabetes. Our overall aim is to create a platform allowing monitoring and treatment of insulin-dependent diabetes in mice that can be transferred to large animals for validation. The objective is to combine tissue engineering of islet cell organoids, transplantation to the ACE, synthetic biology, local pharmacological treatment strategies and the development of novel micro electronic/micro optical readout systems for islet cells. This regenerative medicine approach will follow our clinical trial programs and be transferred into the clinic to combat diabetes.