Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
SUper-Resolved comPRessive InStrument in the visible and medium infrared for Earth observation applications (SURPRISE)

Framework: Horizon 2020 — Industrial Leadership
Programme: Space
Theme: Enabling advances in space technology
Action type: Research and Innovation actions
Countries involved: Italy,Italy,Germany,Italy,Switzerland,France
Call: Earth observation technologies (H2020-SPACE-2019, 2019)
Start date: 2020-01-01
End date: 2023-06-30
Duration (months): 42.0
Total project cost (EUR): 2988795.0
EU funding (EUR): 2988795.0
Participants: 8
Project status: SIGNED

While Earth Observation (EO) data has become ever more vital to understanding the planet and addressing societal challenges, applications are still limited by revisit time and spatial resolution. Though low Earth orbit missions can achieve resolutions better than 100 m, their revisit time typically stands at several days, limiting capacity to monitor dynamic events. Geostationary (GEO) missions instead typically provide data on an hour-basis but with spatial resolution limited to 1 km, which is insufficient to understand local phenomena. SURPRISE’s main objective is to implement a demonstrator of a super-spectral EO payload - working in the visible, near- and mid-infrared and conceived to operate from GEO platform - with enhanced capability in spatial resolution, onboard data processing and encryption functionalities. SURPRISE develops two disruptive technologies: Compressive Sensing (CS) and Spatial Light Modulator (SLM). CS optimises data acquisition (e.g. reduced storage and transmission bandwidth requirements) and enables novel onboard processing and encryption functionalities. SLM here implements the CS paradigm and achieves a super-resolution architecture. SLM technology, at the core of the CS architecture, is addressed by: reworking and testing off-the-shelf parts in relevant environment; developing roadmap for a European SLM, micromirror array-type, with electronics suitable for space qualification. By introducing for the first time the concept of a payload with medium spatial resolution (few hundreds of meters) and near continuous revisit (hourly), SURPRISE can lead to a EO major breakthrough and complement existing operational services. CS will address the challenge of large data collection, whilst onboard processing will improve timeliness, shortening time needed to extract information from images and possibly generate alarms. Impact is relevant to industrial competitiveness, with potential for market penetration of the demonstrator and its components.

Keywords: optical payload,compressive sensing,super spectral,super resolution,spatial light modulator,micromirror array,encryption,onboard processing,fpga,relevant environment,single pixel camera
Dysfunctional mitochondria as a neuronal pathogen (MitoTROJAN)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Spain
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-12-01
End date: 2024-05-29
Duration (months): 24.0
Total project cost (EUR): 172932.48
EU funding (EUR): 172932.48
Participants: 1
Project status: SIGNED

The symbiosis between the mitochondrion and the ancestor of the eukaryotic cell allowed cellular complexity. Due to its archeobacterial origin, mitochondria has been posited as a potential source of molecules that can elicit cellular responses to pathogens. Among other key functions, mitochondria generates most of the energy required by cells. Alterations in components of the mitochondrial energy-generating machinery lead to primary mitochondrial disease (MD), a group of highly invalidating human conditions with no effective treatment. High-energy-requiring cells, such as neurons, are especially affected in MD. However, not all neuronal populations are equally affected and the molecular determinants of this susceptibility are currently unknown. Recently, Quintana´s lab uncovered that GABAergic neurons in the Globus Pallidus (GPe) of a mouse model of Leigh syndrome (LS) are particularly sensitive to MD leading to fatal encephalopathy, recapitulating the human pathology. In addition, unpublished results of the host group showed that this neuronal population develop a robust cellular antiviral-like response elicited by mitochondrial double-stranded RNA (mtdsRNA). Nevertheless, the contribution of mtdsRNA release in the MD progression has never been defined. Thus, the main goal of MitoTROJAN is to identify the effect of mtdsRNA-induced neuropathology in the context of mitochondrial dysfunction with the overarching goal of providing novel targets for the treatment of MD. By combining mouse genetics with cutting-edge molecular biology and multi-omics approach, I will carry out a multidisciplinary strategy to i) parse the molecular mechanisms of mtdsRNA-induced neuropathology and ii) characterise the antiviral response-induced protein shutdown in affected neurons. Overall results will provide new insight on an uncharacterized mechanism of mitochondria-mediated neurodegeneration and will help to identify novel therapeutic targets for MD and other neurodegenerative diseases.

Keywords: gabaergic neurons,mitochondria,mitochondrial disorders,mitochondrial double stranded rna,antiviral response,neurodegeneration
RESCCUE - RESilience to cope with Climate Change in Urban arEas - a multisectorial approach focusing on water (RESCCUE)

Framework: Horizon 2020 — Societal Challenges
Programme: Climate action, environment,  resource efficiency and raw materials
Action type: Innovation actions
Countries involved: Spain,Spain,France,United Kingdom,United Kingdom,Portugal,United Kingdom,Kenya,United Kingdom
Call: Disaster Resilience & Climate Change topic 1: Science and innovation for adaptation to climate change: from assessing costs, risks and opportunities to demonstration of options and practices (H2020-DRS-2015, 2015)
Start date: 2016-05-01
End date: 2020-11-30
Duration (months): 55.0
Total project cost (EUR): 8057266.65
EU funding (EUR): 6896991.76
Participants: 23
Project status: CLOSED

RESCCUE aims to deliver a framework enabling city resilience assessment, planning and management by integrating into software tools new knowledge related to the detailed water-centred modelling of strategic urban services performance into a comprehensive resilience platform. These tools will assess urban resilience from a multisectorial approach, for current and future climate change scenarios and including multiple hazards. The project will review and integrate in the general framework existing options to assess climate change impacts and urban systems vulnerabilities allowing to assess multisectorial dependencies under multiple climate change scenarios. An adaptation strategies portfolio, including climate services, ecosystem-based approaches and resource efficiency measures will be incorporated as key components of the deployment strategy. The possible approaches will be ranked by their cost-efficiency in terms of CAPEX and OPEX to evaluate their benefits potential. This will enable city managers and urban system operators deciding the optimal investments to cope with future situations. The validation platform is formed by 3 EU cities (Barcelona, Lisboa and Bristol) that will allow testing the innovative tools developed in the project and disseminating their results among other cities belonging to major international networks. In terms of market potential, RESCCUE will generate large potential benefits, in terms of avoided costs during and after emergencies, that will contribute to their large-scale deployment. The structure of the consortium will guarantee the market uptake of the results, as the complete value chain needed is already represented. The project is coordinated by Aquatec, a large consultancy firm part of a multinational company focused on securing and recovering resources, and includes partners from the research domain, operation of critical urban systems, city managers and international organisations devoted to urban resilience.

Keywords: urban resilience,climate change,multisectorial approach,urban services,adaptation strategies,cost benefit analysis,urban resilience platform
Neural correlates of working memory control in aged bilinguals (NeWMaBIL)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-01-01
End date: 2017-12-31
Duration (months): 24.0
Total project cost (EUR): 165598.8
EU funding (EUR): 165598.8
Participants: 1
Project status: CLOSED

Identification of factors that slow down cognitive depletion in ageing is today one of the main objectives of the aged society. Within the concept of cognitive reserve (CR), bilingualism has evidenced to shape cognition by enhancing the capacity of cognitive control (CgCnt). CgCnt and working memory (WM) capacities are strongly interrelated systems which are depleted by ageing. However, the exploration of how bilingualism shapes cognition in old populations is scarce and recently subjected to debate. Under this framework, sensitive approaches (such as the exploration of the neural oscillatory activity) that enable objective investigation of the effects of bilingualism on cognitive ageing are necessary. Neural oscillations represent the mechanisms responsible for cognition. Furthermore, they offer a direct measure of the cognitive architecture and of any reorganizational process accounting in the brain by factors as bilingualism. Nevertheless, the neural code of WM control in old bilinguals has not been explored yet. The current project aims to investigate, with magnetoencephalography (MEG), the neural correlates of WM control in young and old adult bilingual individuals. Resulting data will open a window into the role of bilingualism on the neural architecture of the working brain.

Keywords: ageing,bilingualism,working memory,neural oscillations
Chronic Systemic Inflammation: Functional organ cross-talk in inflammatory disease and cancer (CSI-Fun)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Physiology in Health, Disease and Ageing
Panel description: Organ and tissue physiology, comparative physiology, physiology of ageing, pathophysiology, interorgan and tissue communication, endocrinology, nutrition, metabolism, interaction with the microbiome, non-communicable diseases including cancer (and except disorders of the nervous system and immunity-related diseases)
Countries involved: Austria,Spain
Call: ERC Advanced Grant (ERC-2016-ADG, 2016)
Start date: 2018-06-01
End date: 2024-05-31
Duration (months): 72.0
Total project cost (EUR): 2499875.0
EU funding (EUR): 2499875.0
Participants: 2
Project status: SIGNED

Chronic Systemic Inflammation (CSI) resulting from systemic release of inflammatory cytokines and activation of the immune system is responsible for the progression of several debilitating diseases, such as Psoriasis, Arthritis and Cancer. Initially localised diseases can result in CSI with subsequent systemic spread to distant organs, a key patho-physiological phase responsible for major morbidity and even mortality. Despite the importance of CSI, a complete understanding of the molecular mechanisms, signalling pathways and cell types involved, as well as the chronological evolution of the systemic inflammatory response is still elusive. The classical approach to study inflammation has focused on investigating individual cell types or organs in the pathogenesis of a single disease, thereby neglecting important organ cross-talk and systemic interactions. Furthermore, understanding the temporal and spatial kinetics modulating the inflammatory response requires a detailed study of interactions between different immune and non-immune organs at various time points during disease progression in the context of the whole organism. The aim of this research proposal is to substantially advance our understanding of whole organ physiology in relation to systemic inflammation as a cause or/and consequence of disease with the focus on Psoriasis/Joint Diseases and Cancer Cachexia. The goal is to elucidate the molecular mechanisms at the cellular and systemic level, and to decipher endocrine interactions and cross-talks between distant organs. Various model systems ranging from cell cultures to genetically engineered mouse models to human clinical samples will be employed. Genomic, proteomic and metabolomic data will be combined with functional in vivo assessment using mouse models to understand the multi-faceted role of systemic inflammation in chronic human diseases, such as Inflammatory Skin/Joint disease and Cachexia, a deadly systemic manifestation of Cancer.

Keywords: mouse models for common human diseases,cancer,inflammation
UnderWater Information Technology (UWIT) (UWIT)

Framework: Horizon 2020 — Industrial Leadership
Programme: Information and Communication Technologies
Action type: SME instrument
Countries involved: Finland
Call: Open Disruptive Innovation Scheme (H2020-SMEINST-2-2016-2017, 2016)
Start date: 2016-10-01
End date: 2018-09-30
Duration (months): 24.0
Total project cost (EUR): 1194875.0
EU funding (EUR): 836412.5
Participants: 1
Project status: CLOSED

Alleco, a Finnish SME, has developed the world’s first tablet computer with a fully functional touchscreen that works under water. With patented core technology, 25 years of experience in the industry and existing cooperation with the world’s leading diving equipment distributor, Aqua Lung, Alleco is well positioned to bring this novel solution rapidly to the market. With the developed product Alleco is expecting to realize its growth strategy and become a global leader in providing the diving industry with ground-breaking new information and communication technologies. Alleco’s objective with this project is to replicate the market success of consumer mobile devices in an underserved market on a global scale. The proposed outcome of the project will be an ICT solution for professional divers - ranging from scientists, military and fire&rescue to dive instructors - that will disrupt the market for diving equipment and decrease the costs of an average diving project by more than 50%. On a longer time scale, additional market segments include offshore oil&gas, the mining industry, as well as the medical industry, where electronic devices that are dust- and water proof, easy to clean, as well able to operate in explosive prone areas, are in high demand, but short supply. The specific objectives of the project are to finalize the necessary hardware (TRL7) and software (TRL7) components and to develop an underwater data exchange- and positioning system (TRL7). Pilot testing will help to validate the full solution in real-life environments and raise customer awareness. The successful implementation of the UWIT project will open up a route to a potential target market of €2,82Bn. By 2021 Alleco expects to earn more than 53MEUR annually from the project results, and reach a turnover in excess of 100 MEUR by 2024.

Keywords: underwater ict,consumer technology,technology development,underserved markets,touchscreen,disruptive innovation,rapid growth,mobile data
A general method for developing high-efficiency organic light-emitting diodes based on AIE-active room-temperature phosphorescent polymers (AIE-RTP-PLED)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2020-10-12
End date: 2022-10-11
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

Organic light-emitting diodes (OLEDs) as displays and luminaires have generated enormous attention because of their unique advantages compared to other lighting and display technologies. These include the capacity to fabricate ultra-thin, flexible and transparent devices that additionally have a much lower power consumption. Limited by the electron spin statistics, the maximum internal quantum efficiency (IQE) of conventional fluorescent OLEDs is only 25%. In contrast, thermally activated delayed fluorescence (TADF) can theoretically realize 100% IQE by recruiting triplet excitons and converting them into singlet excitons via reverse intersystem crossing. Most TADF materials must be doped into a rigid host matrix in order to suppress aggregation-caused quenching (ACQ) and other nonradiative processes. An alternative mechanism where 100% IQE can be realized is room temperature phosphorescence (RTP). This proposal targets the development of polymers that are both RTP and show aggregation induced emission (AIE). This permits these materials to be used as high-efficiency emitters in low-cost solution-processed OLEDs. Due to the synergistic effect of AIE, RTP, and polymer, high-efficiency RTP materials can be developed in the amorphous state, a previously undocumented advance in materials development. Through this research proposal, a general road map for simple and high-efficiency PLEDs will be constructed based on AIE-RTP polymers.

Keywords: aggregation induced emission,room temperature phosphorescence,luminescent polymers,light emitting diodes,organic semiconductors
GRant AllocatioN Disparities from a gender perspective (GRANteD)

Framework: Horizon 2020 — Science with and for Society
Programme: Promote gender equality in particular by supporting structural change in the organisation of research institutions and in the content and design of research activities
Action type: Research and Innovation actions
Countries involved: Germany,Spain,Austria,Sweden,Sweden,Netherlands
Call: Analysing gender gaps and biases in the allocation of grants (H2020-SwafS-2018-1, 2018)
Start date: 2019-01-01
End date: 2023-10-31
Duration (months): 58.0
Total project cost (EUR): 1999525.0
EU funding (EUR): 1999525.0
Participants: 6
Project status: SIGNED

In the GRANteD project we study the occurrence and causes of gender bias in the allocation of research grants, We also study the consequences of gender bias in grant allocation for gender bias in the development of careers in research and innovation. Our approach is distinct, because we (i) do not take every gender gap or different success rate as bias, but develop a model that includes variables such as past performance of the applicant and quality of the proposal that may influence the grant allocation. Then (ii) after controlling for the relevant variables we test whether gender has an effect on the grant allocation outcomes, that is gender bias. After in this way having determined where gender bias occurs in grant allocation, we (iii) identify the causes of gender bias, which may be in the procedures, in the criteria deployed, in the evaluation processes, or in composition of the panels, and result in e.g. gender stereotyping or in gendered application of criteria. Finally we analyse (iv) the effects of (biased) grant allocation on careers, but also vice versa, as career level of applicants may recursively influence grant allocation. In order to generate results that can be generalised, the analysis covers a heterogeneous set of funding organizations and funding instruments. For several cases data are already available, for others new data will be collected. A series of methods will be used, from interviews and observations to qualitative text analysis, quantitative multi-level analysis and event history analysis. By maintaining intensive and productive interactions with stakeholders, the project will be targeted on real life problems around grant allocation and careers, and will maximise the impact of the findings.

Keywords: gender bias,grant awarding processes,multivariate and multilevel analysis,impact,research careers,application behaviour,participatory research design,stakeholder process
Understanding Statehood through Architecture: a comparative study of Africa's state buildings (ASA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Institutions, Governance and Legal Systems
Panel description: Political science, international relations, law
Countries involved: United Kingdom,United Kingdom
Call: ERC Consolidator Grant (ERC-2017-COG, 2017)
Start date: 2018-09-01
End date: 2024-03-31
Duration (months): 67.0
Total project cost (EUR): 1870665.0
EU funding (EUR): 1870665.0
Participants: 2
Project status: SIGNED

The project will develop a new ethnography of statehood through architecture. It goes beyond conventional approaches to statehood, which describe states as an objectively existing set of tools used to run a country, and critical approaches that understand them as discursive constructs. Instead, this research understands statehood as a result of the relationship between functions and symbols, and will read it through an innovative new methodology, namely a study of state architecture. The study will focus on state buildings in Africa. African statehood, uncertain and often ambiguous, in many cases profoundly shaped by colonial heritages and post-colonial relationships, is reflected in classical-colonial, modernist-nationalist and post-modern or vernacular styles of architecture. African state buildings reveal the complex interplay of ideas, activities and relationships that together constitute an often uncomfortable statehood. They symbolise the state, embodying and projecting ideas of it through their aesthetics; they enable its concrete functions and processes; and they reveal what citizens think about the state in the ways they describe and negotiate them. The study is comparative, multi-layered and interdisciplinary. It focuses on five countries (South Africa, DR Congo, Ethiopia, Ghana and Côte d’Ivoire), exploring politics and statehood on domestic, regional and international levels, and drawing on theory and methods from political science, history, sociology, art and architecture theory. It employs innovative ethnographic methods, including the collection and display of photographs in interactive exhibitions staged in Africa to explore the ways citizens think about and use state buildings. This project will provide an innovative reading of how African statehood is expressed and how it looks and feels to African citizens. In doing this, it will make a distinctive new contribution to understanding how statehood works everywhere.

Keywords: states,africa,architecture