Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Transition metal carbides as efficient catalysts for methane partial oxidation (TMC4MPO)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Chemistry
Countries involved: United Kingdom
Call: Individual Fellowships (H2020-MSCA-IF-2019, 2019)
Start date: 2021-03-01
End date: 2023-02-28
Duration (months): 24.0
Total project cost (EUR): 212933.76
EU funding (EUR): 212933.76
Participants: 1
Project status: CLOSED

Methane is a particularly problematic greenhouse gas as its impact is 25 times greater than carbon dioxide over a 100-year period. Human activity has increased the amount of methane in the atmosphere, contributing to climate change. Therefore, there is an imperative for the transformation of methane into useful chemicals. At this time, the most economically available route for the conversion of methane into more valuable chemicals is via synthesis gas, a mixture of CO and H2. The only large-scale process for natural gas conversion involves a reaction known as methane-steam reforming. However, it is an endothermic process that requires high operating temperatures. Methane partial oxidation (MPO) is a promising energy saving alternative because it does not require the use of superheated steam. A major goal is to find a catalyst that exhibits high activity, selectivity and stability at the relevant reaction conditions. This project envisions the computational prediction of novel MPO catalysts that overcome this challenges by computationally screening a large set of materials consisting of precious metals (Rh, Pd, Pt, Au) and more affordable metals (Co, Ni, Cu) supported on transition metal carbides (TMCs, TM = Ti, Zr, Hf, V, Nb, Ta, Mo, W). These type of catalysts have exhibited outstanding performance in other chemical reactions in the past 5 years. To this end, state-of-the-art Density Functional Theory and Kinetic Monte Carlo frameworks will be employed to provide direct predictions of activity, selectivity, stability and yield for the most promising catalysts at relevant reaction conditions. Moreover, the large amount of results gathered from this project will serve as a big dataset to conduct descriptor analysis, and will suggest key properties that correlate well with their activity for C-H and O-H bond activation. The results obtained will be discussed with our experimental collaborators, who will prepare a selected set of catalysts based on my findings.

Keywords: methane partial oxidation,syngas,transition metal carbides
A Competitive Intelligence Cloud/HPC Platform for AI-based STI Policy Making (IntelComp)

Framework: Horizon 2020 — Societal Challenges
Programme: Europe in a changing world - inclusive, innovative and reflective societies
Theme: Innovative societies
Action type: Innovation actions
Countries involved: Spain,Spain,Austria,Spain,Greece,Greece,Belgium,Greece,Latvia,France
Call: Pilot on using the European cloud infrastructure for public administrations (H2020-SC6-GOVERNANCE-2020, 2020)
Start date: 2021-01-01
End date: 2023-12-31
Duration (months): 36.0
Total project cost (EUR): 4362935.75
EU funding (EUR): 3998130.2800000003
Participants: 14
Project status: SIGNED

IntelComp sets out to build an innovative Cloud Platform that will offer Artificial Intelligence based services to public administrators and policy makers across Europe for data- and evidence-driven policy design and implementation in the field of Science, Technology and Innovation (STI) policy. Large STI datasets are processed on High Performance Computing (HPC) environment part of the European Open Science Cloud (EOSC) imitative. Public administration at all geographical and organizational levels, STI stakeholders and civil society produce a great amount of dynamic, multilingual and heterogeneous data (i.e. national STI strategies, plans and work programmes, calls, projects, reports, scientific publications, patents, dissemination articles, etc.), so understanding and analyzing this data is crucial for evidence-based policy making. The objective of IntelComp is to deliver a platform that provides tools for assisting the whole spectrum of STI policy, i.e., agenda setting, modeling design, implementation, monitoring and evaluation. It will do so by involving multi-disciplinary teams to co-develop innovative analytics services, Natural Language Processing pipelines and Artificial Intelligence workflows and by exploiting open data, services and computational resources from the EOSC, HPC environments and federated distributed operations at the European Union, national and regional level. It will ensure a cooperative environment where different actors can visualize, interact and analyze information. Through co-creation, IntelComp will adopt a living labs approach and will engage public policy makers, academia, industry, SMEs, local actors, civil society and citizens to explore, experiment with and evaluate STI policies at all stages. IntelComp will be targeting domains aligned with the European Agenda and the Horizon Europe Missions: Artificial Intelligence, Climate Change and Health.

Keywords: natural language processing,text mining,citizen,academia and industry engagement
Transposable elements, their controllers and the genesis of human-specific transcriptional networks (TRANSPOS-X)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Integrative Biology: from Genes and Genomes to Systems
Panel description: Genetics, epigenetics, genomics and other ‘omics studies, bioinformatics, systems biology, genetic diseases, gene editing, innovative methods and modelling, ‘omics for personalised medicine
Countries involved: Switzerland
Call: ERC Advanced Grant (ERC-2015-AdG, 2015)
Start date: 2017-01-01
End date: 2021-12-31
Duration (months): 60.0
Total project cost (EUR): 2500000.0
EU funding (EUR): 2500000.0
Participants: 1
Project status: CLOSED

Transposable elements (TEs) account for more than two thirds of the human genome. They can inactivate genes, provide novel coding functions, sprinkle chromosomes with recombination-prone repetitive sequences, and modulate cellular gene expression through a wide variety of transcriptional and posttranscriptional influences. As a consequence, TEs are considered as essential motors of evolution yet they are occasionally associated with disease, causing about one hundred Mendelian disorders and possibly contributing to several human cancers. As expected for such genomic threats, TEs are subjected to tight epigenetic control imposed from the very first days of embryogenesis, in part owing to their recognition by sequence-specific RNA- and protein-based repressors. It is generally considered that the evolutionary selection of these TE controllers reflects a simple host-pathogen arms race, and that their action results in the early and permanent silencing of their targets. We have recently uncovered new evolutionary evidence and obtained genomic and functional data that invalidate this dual assumption, and suggest instead that transposable elements and their epigenetic controllers establish species-specific transcriptional networks that play critical roles in human development and physiology. The general objective of the present proposal is to explore the breadth of this phenomenon, to decipher its mechanisms, to unveil its functional implications, and to probe how this knowledge could be exploited for basic research, biotechnology and clinical medicine.
Development of innovative 50 kW SOFC system and related value chain (INNO-SOFC)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Public-private partnerships
Destination: Fuel Cells and Hydrogen
Action type: Research and Innovation actions
Partnership: FCH2 (Art-187)
Countries involved: Germany,Germany,Italy,Finland,Netherlands
Call: Innovative fuel cell systems at intermediate power range for distributed combined heat and power generation (H2020-JTI-FCH-2014-1, 2014)
Start date: 2015-09-01
End date: 2019-10-31
Duration (months): 50.0
Total project cost (EUR): 3998081.25
EU funding (EUR): 3998081.25
Participants: 7
Project status: CLOSED

INNO-SOFC project combines leading European SOFC technology companies and research centres to collaborate and form required phases in the SOFC value chain. Within this project a next generation 50 kW SOFC system together with its key components will be developed, manufactured, and validated. This system includes many significant improvements compared to current State of the Art, leading to 30000 hours operating time, 4000 €/kW system costs, 60% electrical efficiency, and 85% total efficiency, which are required for large-scale commercialization of stationary fuel cells. Efficiency, performance, and life-time of the system and its key components will be validated according to IEC standards in conditions that are relevant for end-users. Proof of reliability and durability of the system will be achieved in 3000 hours demonstration together with 10000 hours stack validation runs. The project is based on the products of industrial partners (Convion, EnergyMatters, Elcogen, and ElringKlinger) and motivated by their interest to further improve their products and consolidate an efficient value chain by collaboration. Industrial partners are operating at different phases of the value chain and are not therefore competing against each other, which enables an efficient collaboration and knowledge sharing within the project. Within this approach, whole system and its components will be optimized comprehensively to fulfil and exceed end-users' requirements. Research centres (VTT, Jülich, and ENEA) support these companies to develop, experimentally validate and demonstrate their products. Effective exploitation and dissemination of resulting improved products, services, and know-how is a natural purpose of each partner and these actions are boosted by this project. This makes project results available also for other parties and increases competitiveness of European fuel cell industry.

Keywords: value chain,validation,demonstration,concept analysis
Multi-well High-resolution Electrophysiology Platform (MwHresEP)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Switzerland
Call: ERC-Proof of Concept-2016 (ERC-2016-PoC, 2016)
Start date: 2017-06-01
End date: 2018-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

MwHresEP: Multi-well High-resolution Electrophysiology Platform The aim of this proof-of-concept project is to make initial steps in translating the high-density microelectrode array (HD-MEA) chip technology, which has been developed in the ERC project “NeuroCMOS” (AdG 267351, Subproject 1) into a commercial product. The project will be performed in collaboration with the spin-off company MaxWell Biosystems AG (http://www.mxwbio.com/) that has been founded after the NeuroCMOS project end by collaborators of the PI laboratory and a lab at Riken (Japan) with the purpose to commercialize the developed CMOS-based chip technology and software for neuroscientific research and industrial use in drug discovery and development. The initial steps undertaken in this PoC include (i) the development of a multi-well-plate prototype, suitable for drug discovery applications, that can host CMOS microelectrode arrays in each well. Moreover, we will (ii) develop the needed soft- and hardware to prove the feasibility of integrating the chip system prototype into cell-culture automation platforms, and we will work to (iii) obtain initial data from commercially available human induced-pluripotent-stem-cell (iPSC) -derived neurons.

Keywords: electrophysiology,microelectrode arrays,extracellular recording,well plate multi well plate,drug screening,human induced pluripotent stem cells
A Training Network on Designing Novel Bio-based Fibre Products for Targeted Advanced Properties and New Applications (FibreNet)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Innovative Training Networks (ITN)-European Training Networks
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Austria,Germany,Austria,Belgium,Slovenia,Sweden,Finland,Slovenia,Slovenia,Sweden,Switzerland,Finland,Netherlands
Call: Innovative Training Networks (H2020-MSCA-ITN-2017, 2017)
Start date: 2017-12-01
End date: 2022-05-31
Duration (months): 54.0
Total project cost (EUR): 3832629.48
EU funding (EUR): 3832629.48
Participants: 16
Project status: CLOSED

FibreNet will train young fibre-professionals having multidisciplinary view to develop sustainable bio-based fibre products with tailored properties for different application fields in both academic and non-academic sectors. Bio-based fibre products are one of the corner-stones in the European bio-based industry corresponding to 12% of the employment in manufacturing. The industry, including such sectors as packaging, paper, biocomposites and biomedical and hygienic textiles, is currently undergoing a fundamental transformation in order to respond to the competition raised i) by low-wage countries and ii) by fossil-based materials. A common consensus in Europe is that to remain competitive and sustain the bio-based fibre industries in Europe, we should focus on developing new high added value products that have specific functionalities but reduced environmental impacts. In fibre-based products, developing new properties and improving the performance are, however, typically long and time-consuming processes. They usually involve massive and expensive laboratory and pilot-scale trials, which are followed by statistical analyses. There is a particular knowledge gap in understanding the influence of fibre and fibre interface properties on the mechanical properties of the end-product especially when developing products with tailored performance and functionalities. In addition to the research gap, there is a training gap in Europe, as we do not currently have a training programme which would educate professionals having a skill set needed for the fibre-centered approach that we propose in FibreNet. To fill the research and training gaps, we propose here a unique training and research network which provides and further develops knowhow, methods and tools in functionalization, characterization, numerical modelling and production of bio-based fibre products at multiple length scales. The network covers expertise on packaging, paper, biocomposites and biomedical textiles.

Keywords: bio based fibre,fibre bond,mechanical characterization,functionalization,modelling,colloid and surface chemistry,microrobotics,biocomposites,packaging,wound healing,cell scaffolds,cellulose
RoundBaltic - Promotion of Smart Finance for Smart Buildings in the Baltic Region with focus on Poland, Latvia and Denmark (RoundBaltic)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure, clean and efficient energy
Theme: Reducing energy consumption and carbon foorpint by smart and sustainable use
Action type: Coordination and support actions
Countries involved: Poland,Poland,Poland,Poland,Poland,Poland,Latvia,Denmark,Denmark
Call: National roundtables to implement the Smart Finance for Smart Buildings initiative (H2020-LC-SC3-EE-2020-1, 2020)
Start date: 2020-09-01
End date: 2023-08-31
Duration (months): 36.0
Total project cost (EUR): 1126437.5
EU funding (EUR): 1126437.5
Participants: 11
Project status: SIGNED

A main objective of the RoundBaltic project is to provide framework and catalyst for energy efficiency investments, incl. creating dialogue and enabling actions around the Smart Finance for Smart Buildings initiative and the financial pillars. The direct target countries are Poland, Latvia and Denmark, building on the activities of the Sustainable Energy Investment Forums initiative. The action will develop a supporting framework with activities such as 1) analysing the possibility to upscale existing best practices, develop strategies, roadmaps and action plans, 2) propose improvements in the national policy frameworks and measures, and 3) develop jointly template documents and contracts for a better functioning of the market, and will implement Roundtables where stakeholders can learn from successful initiatives, and can provide input into the policy making. The consortium will pursue a combined approach of addressing the national level (framework conditions) and regional level (topics of relevance for the given regions). Additionally, the project will develop enabling actions aiming to generate sustainable energy investments within the targeted energy efficiency areas of the call and will undertake in-depth evaluation of the impact gained as well as lessons learned of the operations in each target country. It will also provide networking and experience exchange among the stakeholders in each country as well as among the target countries where it makes sense. The project findings and achievements will be disseminated to relevant target groups, incl. other Baltic countries. Moreover, a small share of activities will be reserved to exchange with similar roundtables across Europe (coordinated by the Commission services).

Keywords: roundtables in poland,latvia and denmark,stakeholder dialogue,innovative financing instruments,triggering energy efficiency investments,financing platforms,capacity building,dissemination
Documenting Sarajevo: City and Society During and After the War (EVIDENCITY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: Netherlands
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2015, 2015)
Start date: 2016-09-01
End date: 2018-08-31
Duration (months): 24.0
Total project cost (EUR): 177598.8
EU funding (EUR): 177598.8
Participants: 1
Project status: CLOSED

The aim of this architectural research is to analyses material transformations of Sarajevo—the destruction and reconstruction caused by the war (1992-1996), from documents (videos, photos, and drawings) produced by citizens. Finding these documents is important in the shared process of collective memory creation by Bosnians, but also for academic research and post-war reconstructions. For EU citizens, understanding Sarajevo citizens’ experience can help them to understand the realities of life of the actual war contexts (i.e. Syria). As a citizen who experienced the war, an architect and a researcher of the war cities, my research objective is to expand architectural research methods by focusing on how war affects the transformation of cities through a process combining architecture and media research. I will apply interdisciplinary research methods used in architecture/planning (i.e. geographic information system - GIS), media studies (i.e. video) and anthropology (i.e. interviews). To use media tools is a complement to architect research and representation (i.e. video) modes because they create documents (i.e. drawings) understandable only to architects. Research will be accessible to scientific and general public through a web platform, called Evidencity, which will include map-based, multimedia research archive. Regarding to my academic career this project contributes: obtaining academic profile in the fields of architectural research methods and media for researching of different war cities; advancing my skills as an architect (i.e. analysis of the destroyed city) for working on projects related to the post-war reconstruction. The European continent is constantly dealing with states of war, on its territories (Ukraine) or on its borders (Libya-Italy). Proposal aims to contribute using research results to create interdisciplinary guidelines for architectural research to the emerging field of urban conflict studies that will be applicable to the other war cities.

Keywords: documenting of the war,architecture and media,war material transformations,research methods
Global mapping of second messenger c-di-GMP signaling networks in bacteria using proteomics (SNiB-cdG-P)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: Switzerland
Call: Individual Fellowships (H2020-MSCA-IF-2020, 2020)
Start date: 2021-03-01
End date: 2023-02-28
Duration (months): 24.0
Total project cost (EUR): 191149.44
EU funding (EUR): 191149.44
Participants: 1
Project status: CLOSED

To survive in diverse niches, bacteria must adapt to changes in their local environment by sensing and responding to environmental cues. External cues are transduced through complex signaling networks throughout a cell and drive diverse changes in cellular behavior. In bacteria, cyclic di-guanosine-monophosphate (c-di-GMP) is a nucleotide-derived second messenger that mediates signal transduction of important biological processes for bacterial growth and survival e.g. motility, biofilm formation and metabolism. These biological processes are also crucial in clinical settings as they underlay antibiotic resistance in important pathogenic bacteria. Recent advances in MS-based proteomics have provided different tools to investigate the proteome of an organism in a systematic and global manner. Especially, thermal proteome profiling (TPP) and limited-proteolysis MS (LiP-MS) are pioneering methods to study change of protein states proteome-wide. I aim to employ these proteomics based approaches to achieve the global map of the c-di-GMP signaling network in two different bacteria, Escherichia coli and Caulobacter crescentus, both are model organisms of Gram-negative bacteria. Furthermore, I will apply these methods to investigate signaling network of another important second messenger, (p)ppGpp, and explore how the networks of these two messenger molecules interact in bacteria to dictate cellular physiology.

Keywords: second messenger,c di gmp,ppgpp,e coli,caulobacter crescentus