Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
Safe and green Sensor Technologies for self-explaining and forgiving Road Interactive aPplications (SAFE STRIP)

Framework: Horizon 2020 — Societal Challenges
Programme: Smart, green and integrated transport
Action type: Research and Innovation actions
Countries involved: Italy,Austria,Italy,Italy,Germany,Italy,Italy,Spain,Greece,Greece,Greece,Greece,Belgium,France,France,France
Call: Transport infrastructure innovation to increase the transport system safety at modal and intermodal level (including nodes and interchanges) (H2020-MG-2016-Two-Stages, 2016)
Start date: 2017-05-01
End date: 2020-08-31
Duration (months): 40.0
Total project cost (EUR): 4595813.75
EU funding (EUR): 4595813.75
Participants: 19
Project status: CLOSED

SAFE STRIP aims to introduce a disruptive technology that will achieve to embed C-ITS applications in existing road infrastructure, including novel I2V and V2I, as well as VMS/VSL functions into low-cost, integrated strips markers on the road; to make roads self-explanatory and forgiving for all road users (trucks, cars and vulnerable road users, such as PTWs riders) and all vehicle generations (non-equipped, C-ITS equipped, autonomous), with reduced maintenance cost, full recyclability and added value services, as well as supporting real-time predictive road maintenance functions. The vast potential of SAFE STRIP will be demonstrated through applications for: 1) Cooperative safety functions for enhanced ADAS/ARAS equipped and non-equipped vehicles, 2) Road wear level and predictive road maintenance, 3) Road work zones and railway crossings warnings, 4) Merging/intersection support, 5) Personalised VMS’/VDS’ and Traffic Centre Information, 6) Dynamic trajectory estimation and interface to automated vehicles, whereas it will open a new channel to a vast array of 7) Supportive added value services (such as Virtual Toll Collection and Parking booking and charging). It will be evaluated in a test bed in Spain and in France and 2 closed test tracks in Italy and in real life conditions in Greek and Italian highways, with 4 car and 3 PTW demonstrators. This very challenging task is undertaken by a muldisciplinary and complementary Consortium of 18 Partners from 6 countries, with a good representation of all stakeholders: 1 vehicle OEM (CRF), 1 PTW OEM (Piaggio), 2 system integrators and infrastructure installers (3M & CEA), 2 Tier 1 suppliers (CONTI & VALEO), 1 SME (RELAB), 8 R&D Institutes (CERTH, UNITN, UPAT, FhG/IAO, CNR, CIDAUT, CTI and ICCS) and 2 end users (ATTD and Α22) as beneficiaries, under the umbrella of ERTICO; thus providing further access to all key stakeholders in the area.

Keywords: cooperative driving,intelligent infrastructure,vru vulnerable road users,ptw power two wheelers,micro,nano sensors,work zones safety,automated vehicles
Quantum State Assembler (QuStA)

Framework: Horizon 2020 — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Consolidator grants
Action type: ERC actions
Panel: Fundamental constituents of matter
Panel description: Particle, nuclear, plasma, atomic, molecular, gas, and optical physics
Countries involved: Germany
Call: ERC Consolidator Grant (ERC-2016-COG, 2016)
Start date: 2017-04-01
End date: 2023-03-31
Duration (months): 72.0
Total project cost (EUR): 1958101.0
EU funding (EUR): 1958101.0
Participants: 1
Project status: SIGNED

The biggest challenge to using ultracold fermionic atoms to simulate strongly correlated phases is cooling the system to sufficiently low temperatures. The aim of QuStA is to tackle this challenge with a novel bottom-up approach and assemble many-body systems from individually prepared building blocks. This vision has come within reach through recent breakthroughs in our group in preparing and manipulating few-atom systems with unprecedented fidelity. Building on this experience, we will prepare multiple such few-atom systems and develop strategies to merge them adiabatically to form a many-body system. Initially, we will focus on studying the physics of the Hubbard model, which is prototypical of strongly-correlated systems. Starting from many independently prepared double-well systems, we will assemble a finite lattice system of up to 10 x 10 sites with extremely low entropy. Since our approach will allow us full control over the parameters of the system - such as tunneling, interactions, and doping - we will be in the unique position to investigate the low-temperature phase diagram of the Hubbard model. Our quantum state assembly approach will also allow us to go beyond the Hubbard model and investigate the emergence of correlations in other interesting systems. In particular, we will take an innovative approach of preparing and merging itinerant spin chains to explore bi-layered lattice systems and spin ladders. These experiments will have far-reaching implications beyond the field of ultracold atoms. Our systems will provide an ideal platform to benchmark theories on strongly correlated phenomena since it clearly surpasses the capabilities of modern classical computers. We envision that the insight gained from our experiments will lead to the understanding of exotic quantum phenomena, such as high-Tc superconductivity.

Keywords: quantum simulation,hubbard model,few body quantum systems,mesoscopic quantum systems,many body quantum systems
Deep Vein Thrombosis; A Paradigm Change in Treatment through Drug-Free Clot Removal (VETEX)

Framework: Horizon 2020 — Industrial Leadership
Programme: Innovation in SMEs
Action type: SME instrument
Countries involved: Ireland
Call: SME instrument (H2020-SMEInst-2018-2020-2, 2019)
Start date: 2019-05-01
End date: 2021-07-31
Duration (months): 27.0
Total project cost (EUR): 3550920.0
EU funding (EUR): 2485644.0
Participants: 1
Project status: CLOSED

Deep Vein Thrombosis is the 3rd leading cardiovascular disease behind heart attack and stroke with 1.2M cases diagnosed each year in the EU and US. Left untreated, one third of DVT patients will be at risk of clot breaking away causing a Pulmonary Embolism which has a 50% mortality rate. In addition, significant chronic complications often occur such as clot recurrence (30%), chronic limb swelling associated with Post Thrombotic Syndrome (50%), ulceration and amputation. DVT patients are usually treated with drugs. Anticoagulation therapy alone helps prevent clot extension but it does not remove the clot. Other therapies often involve long hospital stays and often require 24-72 hours in ICU due to the significant bleeding risks associated with heavier duty clot busting (Thrombolytic) drugs. The results are poor for patients with large occulsive clots and who are at risk of bleeding, and extremely expensive for healthcare providers. Vetex Medical is an early stage medical device based in Ireland that has developed a platform technology that rapidly removes high volumes of clot form the deep veins without the use of thrombolytic drugs, and so will radically challenge the inefficiencies and economics present in the current management of deep vein thrombosis. Deep Vein Thrombosis in the larger veins of the upper limb represents $600m market opportunity. Interventions in the treatment of DVT have been increasing steadily over the last number of years with growth rates of 15%. This market segment is increasingly ‘on trend’ and set to witness expedited growth over the coming years. Vetex Medical is ambitious in its’ plan to bring the FreeFlow technology to market in both Europe and the US in 2021, through completion of a Clinical Trial and through securing regulatory approvals to allow market entry. The Vetex Medical Team has the skills and experience to develop and commercialise this novel medical technology and to implement a high growth strategy.

Keywords: deep vein thrombosis,clot management,medical device
Understanding how plants overcome drought by controlling stomatal function: applicability and impacts on agriculture (AgroPHYS)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Global Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Australia,Spain
Call: Individual Fellowships (H2020-MSCA-IF-2016, 2016)
Start date: 2017-08-01
End date: 2020-07-31
Duration (months): 36.0
Total project cost (EUR): 263440.8
EU funding (EUR): 263440.8
Participants: 2
Project status: CLOSED

Land plants have coped with drought since they first colonized dry land. Drought is the most frequent cause of water stress – a functional and structural plant response to low water availability. An understanding of the impact, mechanisms and traits underlying drought tolerance in agricultural plant species is essential to improve productivity, and it further represents a major European priority (SFS-01-2016): optimizing agriculture in a changing climate with reduced water availability and a growing population. To address this urgent need it is necessary to first understand how stomata regulate leaf gas exchange, since stomatal is the main limitation of photosynthesis in crops under water stress. Both hydraulic and non-hydraulic or hormonal signals are the main drivers of stomatal regulation. Therefore, AgroPHYS proposes to investigate how these signals interact to protect plants against damaging desiccation. This project will generate physiological knowledge, at UTAS, from a range of experimental techniques and apply it to a physiology-based model and an automatic plant-based sensor to guide both irrigation management and research, at IRNAS-CSIC. The objectives of AgroPHYS are (i) to evaluate the relative importance and coordination of hydraulic and hormonal signals in plant stomatal responses to drought and recovery, and (ii) to apply this knowledge, by means of a mechanistic model and a plant sensor, to predict productivity relative to water consumption in agricultural plant species with different water use strategies. The outgoing research group is at the cutting-edge of physiological research and the environment of learning will provide maximum benefit to the candidate and excellent opportunities to interact with researchers from across the globe. These skills and knowledge will be transferred back to IRNAS-CSIC, providing essential data not only for scientific research on plant function but also for precision agriculture and optimal management of irrigation.

Keywords: stomata,ecophysiology,hydraulic signals,water use efficiency,mechanistic models,plant,sensors
Quantum Coordination and Support Action (QSA)

Framework: Horizon 2020 — Excellent Science
Programme: Future and Emerging Technologies (FET)
Theme: EIC Pathfinder
Destination: Tackling grand interdisciplinary science and technology challenges
Action type: Coordination and support actions
Countries involved: Germany,Germany,Germany,Germany,Switzerland,France
Call: Coordination and Support Action for Quantum Technologies (H2020-FETFLAG-02-2017, 2017)
Start date: 2017-12-01
End date: 2019-03-31
Duration (months): 16.0
Total project cost (EUR): 500000.0
EU funding (EUR): 500000.0
Participants: 6
Project status: CLOSED

Quantum Technologies (QT) represent a disruptive technological shift with far-reaching applications, including secure communication networks, ultra-sensitive sensors and fundamentally new paradigms of simulation and computation. In each of these applications, quantum technologies could result in revolutionary improvements in terms of capacity, sensitivity and speed, and be the decisive factor for success in many industries and markets. The immense potential of this interdisciplinary field has led the European Commission to announce the launch of a FET Flagship on Quantum Technologies (“Quantum Flagship”) in 2018 and to appoint an independent High-Level Steering Committee to give recommendations on its setup. Based on these recommendations and building on previous coordination efforts, we propose the Quantum Coordination and Support Action (QSA) whose primary goal is to prepare the ground for a successful launch of the Quantum Flagship. The QSA initiative is a timely, important and necessary planning step to make sure the full potential of the Quantum Flagship can be attained right from its start. For this to happen, we set out to achieve the following objectives: 1. Facilitate a goal-driven, federated effort to set up the Quantum Flagship, 2. Increase awareness of QT in Europe, and 3. Support detailing and implementing the Flagship’s organisational structure. We believe that these objectives are best achieved by acting in a transparent and inclusive way, ensuring commitment from all key stakeholders (academia, industry and EU and national policy makers) to the Quantum Flagship, and we have structured our work plan accordingly to succeed within the scope and duration of the Coordination and Support Action.

Keywords: quantum technologies,flagship initiative,industry academia cooperation,stakeholders coordination
Biostimulant alternative casing for a sustainable and profitable mushroom industry (BIOSCHAMP)

Framework: Horizon 2020 — Societal Challenges
Programme: Food security, sustainable agriculture and forestry, marine and maritime and inland water research and the bioeconomy
Theme: Sustainable agriculture and forestry
Action type: Innovation actions
Countries involved: Italy,Spain,Spain,Spain,Belgium,Serbia,Poland,Netherlands,Netherlands,Netherlands,United Kingdom
Call: Integrated health approaches and alternatives to pesticide use (H2020-SFS-2020-1, 2020)
Start date: 2020-10-01
End date: 2024-09-30
Duration (months): 48.0
Total project cost (EUR): 4179611.25
EU funding (EUR): 3687540.0
Participants: 14
Project status: SIGNED

The mushroom sector is an excellent example of circular economy to provide high quality protein from crop substrate based on bio-based agricultural wastes. Productivity is however highly sensitive to several biotic disorders among which fungal parasites are responsible for major crop losses. Although chemical fungicides have been historically employed to fight mycoparasites, regulatory limitations for mushroom growers and increasing consumer awareness are urgently requesting solutions to overcome fungicide dependence. Bacterial strains isolated in a previous research from the casing layer employed in mushroom cultivation have proved to selectively suppress germination and development of most harmful mycoparasites, while additionally selected microbiota proved to work as mushroom growth promoting microorganisms. This project aims to develop a tailor-made solution for the mushroom sector where a peat-free casing soil (peat is an unsustainably sourced on which the sector is highly dependent to produce the peat-based casing employed nowadays) will serve as carrier for the selected microbiota that will act as crop biostimulant. This solution will be validated industrially by 4 different mushroom farms across the EU which integrate all the European cropping systems. BIOSCHAMP will generate a solution to improve industrial profitability while reducing the agronomical need for pesticides by 90%. Additionally, BIOSCHAMP solution will introduce innovation within the industry that will lead to create jobs in low populated rural areas and to secure long-term viability of the sector while complying with regulatory restrictions for chemical fungicides and peat-based materials. To accomplish these ambitious goals, the BIOSCHAMP project features a multidisciplinary consortium representing a complete picture of the European mushroom sector and associated industry with high priority given to mushroom growers noteworthy lead by a growers association.

Keywords: biostimulants,pesticide residues,alternative bio based casing,fungicide suppression,mushroom cultivation,circular approach,environmentally sustainable
Optogenetics based discovery of new pathways towards stem-cell mediated myelin repair (STEM ZAP)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: United Kingdom
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2016-04-06
End date: 2018-04-05
Duration (months): 24.0
Total project cost (EUR): 195454.8
EU funding (EUR): 195454.8
Participants: 1
Project status: CLOSED

Neurological disorders, such as multiple sclerosis (MS), that involves degeneration of the myelin sheath exact a social and economic toll on the EU estimated at 14.6 billion Euros per year. Consequently therapies capable of regenerating damaged myelin are an important clinical goal. The aim of this fellowship is to develop new strategies for the replacement of myelin through the use of embryonic stem (ES) cells. We propose to achieve this aim by identifying novel signalling molecules capable of enhancing the generation of myelin-forming oligodendrocytes from ES cells. Membrane depolarisation enhances myelination during postnatal development, and can promote the differentiation of ES-OL cells. However, the impact of depolarisation on the generation of oligodendrocytes from ES cells (ES-OL) is unknown, as are the signalling molecules driving depolarisation-induced ES cell differentiation. Filling these gaps has the potential to deliver new methods for increasing the supply of pro-myelinating ES-OL capable of regenerating damaged myelin. This fellowship will unite supervisor Dr Fulton’s expertise in oligodendrocyte biology and optogenetics with Dr Otsu’s knowledge and skills in novel methods for the efficient production of ES-OL. In addition, partner organisations from the commercial and clinical sectors will add additional expertise that will enhance the project’s research capacity, and ensure success in its goal of developing novel pathways towards myelin regeneration.

Keywords: optogenetics,oligodendrocyte precursor cell,myelination,multiple sclerosis
ROLE OF THE TANYCYTIC BARRIER AT THE BLOOD-HYPOTHALAMUS INTERFACE DURING METABOLIC DISORDER DEVELOPMENT (GLIODIABESITY)

Framework: Horizon 2020 — Excellent Science
Programme: Marie-Sklodowska-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Individual Fellowships (IF)-Standard European Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Life Sciences
Countries involved: France
Call: Marie Skłodowska-Curie Individual Fellowships (IF-EF) (H2020-MSCA-IF-2014, 2014)
Start date: 2015-07-01
End date: 2017-06-30
Duration (months): 24.0
Total project cost (EUR): 173076.0
EU funding (EUR): 173076.0
Participants: 2
Project status: CLOSED

Metabolic disorders such as obesity and diabetes are age-related diseases, and lead cause of death in Europe. Adiposity signals such as leptin and insulin, whose circulating levels are in proportion to body fat, convey metabolic information to neural networks that regulate energy homeostasis in the hypothalamus. In leptin-deficient humans and mice, leptin administration effectively reduces hyperphagia and obesity. Paradoxically, most cases of obesity display high circulating leptin levels that fail to reduce appetite or increase energy expenditure. This raises the possibility that leptin transport across the blood-brain barrier to the cerebrospinal fluid (CSF) or to its sites of action within the hypothalamus is a limiting step defective in obese patients. The host laboratory recently demonstrated that tanycytes, a hypothalamic glia lining the floor of the third ventricle, were responsible for shuttling leptin from the periphery to the CSF and that such conduit was blunted in mice with diet-induced obesity. Leptin transport by tanycytes could thus play a critical role in the pathophysiology of leptin resistance. The overall objective of this project is to further elucidate whether the alteration of the adiposity signals transport into the metabolic brain across hypothalamic barriers is the main cause of the onset of obesity. To this end, a combination of in vitro and in vivo approaches, using genetically modified mice and pre-clinical models of obesity, will be implemented in order to elucidate the molecular mechanisms for the transport of blood-borne leptin into the CSF by tanycytes. It is anticipated that implementation of this project will expand our knowledge of the mechanism underlying human obesity and hold therapeutic potential for treating it. Besides, the proposed project is endowed of solid formative contents that will strengthen the experience of the applicant, boosting her future scientific career and paving the way for closer scientific collaborations.

Keywords: obesity,leptin,hypothalamic barrier,tanycytes,glial cell,er stress
Retrieval and Analysis of Heterogeneous Online Content for Terrorist Activity Recognition (TENSOR)

Framework: Horizon 2020 — Societal Challenges
Programme: Secure societies - protecting freedom and security of Europe and its citizens
Action type: Innovation actions
Countries involved: Germany,Spain,Italy,Germany,Germany,Belgium,Greece,Greece,France,France,United Kingdom,United Kingdom,United Kingdom,United Kingdom,United Kingdom
Call: Law Enforcement capabilities 2: Detection and analysis of terrorist-related content on the Internet (H2020-FCT-2015, 2015)
Start date: 2016-09-01
End date: 2019-11-30
Duration (months): 39.0
Total project cost (EUR): 5579893.51
EU funding (EUR): 4977200.5
Participants: 19
Project status: CLOSED

Law Enforcement Agencies (LEAs) across Europe face today important challenges in how they identify, gather and interpret terrorist generated content online. The Dark Web presents additional challenges due to its inaccessibility and the fact that undetected material can contribute to the advancement of terrorist violence and radicalisation. LEAs also face the challenge of extracting and summarising meaningful and relevant content hidden in huge amounts of online data to inform their resource deployment and investigations. In this context, the main objective of the TENSOR project is to provide a powerful terrorism intelligence platform offering LEAs fast and reliable planning and prevention functionalities for the early detection of terrorist organised activities, radicalisation and recruitment. The platform integrates a set of automated and semi-automated tools for efficient and effective searching, crawling, monitoring and gathering online terrorist-generated content from the Surface and the Dark Web; Internet penetration through intelligent dialogue-empowered bots; Information extraction from multimedia (e.g., video, images, audio) and multilingual content; Content categorisation, filtering and analysis; Real-time relevant content summarisation and visualisation; Creation of automated audit trails; Privacy-by-design and data protection. The project brings together industry, LEAs, legal experts and research institutions. It is expected that this collaboration will have significant impact on 1) ensuring the final system meets end-user LEA requirements, 2) enabling LEAs to access and examine terrorist generated content online bringing significant advantages to their operational capability, and 3) promoting industry’s enhanced understanding of operational LEA requirements and their market competitiveness in the field of online organised crime, terrorism and harmful-radicalisation.