Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
CARbon nanoTube phOtONic devices on silicon (CARTOON)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Future and Emerging Technologies
Action type: Collaborative project
Countries involved: France,Germany,Italy,France
Call:  (FP7-ICT-2013-C, 2013)
Start date: 2013-11-01
End date: 2016-10-31
Duration (months): 36.0
Total project cost (EUR): 1855052.0
EU funding (EUR): 1438037.0
Participants: 4
Project status: CLOSED

Primary goal of the proposed research action is the development of a novel strategy for hybridizing silicon based photonic devices, exploiting semiconducting carbon nanotubes (CNT) as integrated light source, modulator and detector. Photonics in Information and Communication Technologies is more and more investigated for a broad application domain. These applications require efficient optoelectronic devices to emit, modulate and detect light. To facilitate photonic and electronic convergence, the envisioned approach is based on the silicon platform. However, the definition of optoelectronic devices requires several kinds of materials (Si, Ge and III-V) as silicon is an indirect-gap material with poor electro-optic properties. This project aims at investigating a new and innovative field through the use of CNT in the near infrared wavelength range. The main breakthrough will come from the development of CNT-based optoelectronic components directly co-integrated within a silicon platform to address the major challenges of photonics. Such integration has never been investigated so far and thanks to a joint experimental and theoretical investigation our major goal is to establish the potential of CNT technology for nanophotonics applications. The project reposes on three major cornerstones: (i) A waveguide detector in the 1.3-1.6µm wavelength range, (ii) integrated optical modulators using Kerr (electro-refraction) and Stark (electro-absorption) effects and (iii) An integrated electrically pumped optical nanosource. Each of these cornerstones will be a world's premiere and will constitute a breakthrough. Inherently, this makes it a high risk/high gain yet achievable proposal with a foundational impact both in knowledge and technology for nanophotonics. In a long term vision the establishment of new state of the art and advanced know-how on optoelectronic devices based on CNT will allow developing and addressing a broad range of applications in information technologies.

Keywords: carbon nanotubes,silicon photonics,optoelectronics,nanosource,integrated optics,hybrid integration,nanophotonics
TWO!EARS (TWO!EARS)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Future and Emerging Technologies
Action type: Collaborative project
Countries involved: Germany,Denmark,Germany,France,Germany,United Kingdom,Netherlands,United States
Call:  (FP7-ICT-2013-C, 2013)
Start date: 2013-12-01
End date: 2016-11-30
Duration (months): 36.0
Total project cost (EUR): 4013526.0
EU funding (EUR): 2969131.0
Participants: 10
Project status: CLOSED

TWO!EARS replaces current thinking about auditory modelling by a systemic approach in which human listeners are regarded as multi-modal agents that develop their concept of the world by exploratory interaction. The goal of the project is to develop an intelligent, active computational model of auditory perception and experience in a multi-modal context. Our novel approach is based on a structural link from binaural perception to judgment and action, realised by interleaved signal-driven (bottom-up) and hypothesis-driven (top-down) processing within an innovative expert system architecture. The system achieves object formation based on Gestalt principles, meaning assignment, knowledge acquisition and representation, learning, logic-based reasoning and reference-based judgment. More specifically, the system assigns meaning to acoustic events by combining signal- and symbol-based processing in a joint model structure, integrated with proprioceptive and visual percepts. It is therefore able to describe an acoustic scene in much the same way that a human listener can, in terms of the sensations that sounds evoke (e.g. loudness, timbre, spatial extent) and their semantics (e.g. whether the sound is unexpected or a familiar voice). Our system will be implemented on a robotic platform, which will actively parse its physical environment, orientate itself and move its sensors in a humanoid manner. The system has an open architecture, so that it can easily be modified or extended. This is crucial, since the cognitive functions to be modelled are domain and application specific. TWO!EARS will have significant impact on future development of ICT wherever knowledge and control of aural experience is relevant. It will also benefit research in related areas such as biology, medicine and sensory and cognitive psychology.

Keywords: binaural hearing,auditory perception,vision,cognition,bottom-up,top-down,feedback,robotics,object formation,computational auditory scene analysis,meaning,logic-based reasoning,experience.
HypErspectraL Imaging Cancer Detection (HELICOID)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Future and Emerging Technologies
Action type: Collaborative project
Countries involved: Spain,Spain,United Kingdom,Spain,France,United Kingdom,Netherlands
Call:  (FP7-ICT-2013-C, 2013)
Start date: 2014-01-01
End date: 2016-12-31
Duration (months): 36.0
Total project cost (EUR): 1375838.0
EU funding (EUR): 992758.0
Participants: 10
Project status: CLOSED

Starting with some specific types of cancers, this project will try to generalize the methodology to discriminate between healthy and malignant tissues in real-time during surgical procedures. Using the hyperspectral signatures of the healthy tissues and the same tissues affected by cancer, a mathematical model of how cancer affects to the hyperspectral signature will be derived. The research will start with the challenging task of brain cancer detection. A precise resection of the gliomas will minimize the negative effect of removing brain cells while assuring an effective tumour resection. The second type of tumours to be analysed will be the lung and breast cancers as they represent the two most common cancers in the world. Based on the experience gained during the evolution of the project and guided by the oncologist expertise, many other types of cancer out from the more than 200 that affect human beings will be studied. As cancer supposes a change in the cellular physiology, it should be detected as a change in the hyper-spectral signature. This project will try to determine if there is a certain pattern that could be identified as a cancer hyperspectral signature. Although previous works demonstrates that hyperspectral imaging can be used for certain cancer detection in animals, no application to human beings in real-time surgery has been found. This project will develop an experimental intraoperative setup based on non-invasive hyperspectral cameras connected to a platform running a set of algorithms capable of discriminate between healthy or pathological tissues. This information will be provided, through different display devices to the surgeon, overlapping normal viewing images with simulated colours that will indicate the cancer probability of the tissue presently exposed during every instant of the surgical procedure. A high-efficiency hardware/software prototype will be developed with the aim of recognising cancer tissues on real time.

Keywords: hyperspectral imaging cancer detection prototype
Electrical spin manipulation in electroACtive MOLecules (ACMOL)

Framework: FP7 — Cooperation
Programme: Information and Communication Technologies
Destination: Future and Emerging Technologies
Action type: Collaborative project
Countries involved: Spain,Switzerland,Netherlands,Ireland,United Kingdom,Spain
Call:  (FP7-ICT-2013-C, 2013)
Start date: 2014-01-01
End date: 2016-12-31
Duration (months): 36.0
Total project cost (EUR): 1619083.0
EU funding (EUR): 1187431.0
Participants: 6
Project status: CLOSED

The project “Electrical spin manipulation in electroACtive MOLecules” (ACMOL) has the ambitious goal of fabricating a switchable, room-temperature spin-polarizer employing electro-active and magnetic molecules, which are integrated into graphene-type electrodes modified with ferromagnetic materials. The combination of these molecules with ferromagnetic electrodes is a new route in spintronics. Exploiting the high stability of graphene, we aim to demonstrate for the first time good performance of the device at room temperature. The outstanding devices can be applied to a broad number of different technological and societal fields, such as high-density data storage, microelectronics, (bio)sensors, quantum computing and medical technologies. An external electric field will be applied to read and manipulate the state of the device, as well as its charge transport properties. The characterization of the electrical response will be carried out in a 3-terminal configuration composed of source, drain and gate. The charge transport properties of the molecular junctions will be investigated in a solid-state back-gate configuration, as well as in solution, employing an “electrolyte gate”. In this way, the devices will operate as switches that can be exploited to read and write information, which is stored in the oxidation and magnetic state of each molecule. The project involves the synthesis of the functional moieties, the device fabrication and characterization, as well as DFT modelling, which will be based on a fully quantitative description of the electronic structure at non-equilibrium. To accomplish the objectives of the project, we have chosen an interdisciplinary approach with four young research teams representing expertise in synthetic chemistry, molecular self-assembly, molecular-scale surface electrochemistry, device engineering, and DFT-based mesoscopic spin-transport calculations.

Keywords: molecular spintronics,few-layers graphene electrodes,organic radicals,room-temperature performance,switchable spin-polarizer
The coordination of national research activities of Member States and Associated States in the field of Ocean Energy (ERA-NET) (OCEANERA-NET)

Framework: FP7 — Cooperation
Programme: Energy
Destination: Horizontal programme actions
Action type: Coordination and support actions
Partnership: OCEANERA-NET (ERA-NET)
Countries involved: United Kingdom,Spain,Spain,Spain,Spain,Ireland,Sweden,Denmark,France,Belgium,Spain,Netherlands,Portugal,United Kingdom
Call:  (FP7-ERANET-2013-RTD, 2013)
Start date: 2013-12-01
End date: 2018-02-28
Duration (months): 51.0
Total project cost (EUR): 2612982.67
EU funding (EUR): 2205037.57
Participants: 19
Project status: CLOSED

Europe’s vast coast line harbours a huge potential resource of ocean energy to be exploited as a renewable electricity source contributing towards the 2020 targets and beyond. The ocean is a complex working environment, relatively little is known about it and it is widely used by others, such as fishing, shipping and recreation. However, the prize for introducing ocean energy generation is high, estimated by DG MARE, at 380GW. Currently, several member states and regions are funding ocean energy research, demonstration, technology and innovation (RTDI). There is a shared goal to generate knowledge about the marine environment and to speed the development of this emerging sector. However these research efforts are not coordinated. This is why the member states are proposing the Ocean Energy ERA-NET as outlined in this paper. The ERA-NET will provide a framework for transnational joint activities and will cooperate with the EERA Ocean Energy Joint Programme; other relevant European projects and industry stakeholders. This wide reaching ERA-NET brings together 16 partners from nine member states intent on gaining the benefits of coordinated research funding. Member States have different levels of engagement in the ocean energy sector, and it is important that the ERA-NET actions reflect this. The objective is to improve the quality, scope and fragmentation of research through better networks, addressing common barriers and improving coordination. The proposal sets out the execution of the project from networking and information sharing to the launch of, at least one, transnational joint call. In doing so the partners will develop a shared vision for the sector, an action plan for delivery and a toolkit for call administration. The result will be reduced fragmentation in research funding, development and wider uptake of good practice and support for the commercialisation of the ocean energy sector.

Keywords: ocean energy research wave tidal marine
ERA-NET Plus on Infrastructure Innovation (INFRAVATION)

Framework: FP7 — Cooperation
Programme: Transport (including Aeronautics)
Destination: Sustainable surface transport (INCLUDING THE �EUROPEAN GREEN CARS INITIATIVE�)
Action type: Coordination and support actions
Partnership: INFRAVATION (ERA-NET)
Countries involved: Netherlands,Germany,Belgium,Denmark,Norway,Sweden,Iceland,France,Spain,Israel,Germany,Italy
Call:  (FP7-ERANET-2013-RTD, 2013)
Start date: 2014-01-01
End date: 2018-12-31
Duration (months): 60.0
Total project cost (EUR): 9575000.0
EU funding (EUR): 2675000.0
Participants: 12
Project status: CLOSED

Europe needs to redefine its transport system for the 21st century. Performance and cost-efficiency of the system need to be improved to meet future challenges. This means there is an urgent need for effective innovation for all components of the system; including vehicles, infrastructure, logistics etc. Transport ministries across Europe are facing ever tougher challenges to cope with the need to accommodate increased traffic growth, minimise congestion, maintain services in face of increasing climate change effects, as well as deliver on environmental and societal objectives. This is the time when innovation for road infrastructure is an absolute imperative to reduce costs without compromising on quality. To deliver this objective on a transnational basis, the ERA-NET Plus action on infrastructure innovation – Infravation - is initiated enabling national bodies to take on tasks collectively that otherwise could not be taken forward. This scheme will allow for bringing together the efforts of member states, EC and industry. The “Infravation call” will be launched in March 2014 and is expected to be supported through the FP7 2013 Work Programme. Infravation comprises 11 European countries, one region and the EC. For the first time the USA will contribute funding to an ERA-NET Plus. The total pot available for R&D funding amounts to 9,025 M€. The topics addressed reflect the needs of researchers/industry, road infrastructure owners and operators and EC for joint research on road infrastructure. Infravation will pave the way to a new quality of transnational research funding cooperation by applying a real common pot that merges national and EC top-up funding into one funding pot This approach allows for a coordinated, common governance structure for R&D projects funded, enabling the best expertise to be used, regardless of nationality and thereby minimising programme management and allow the maximum use of resources for transnational research cooperation.

Keywords: road infrastructure,innovation,integration
Coordinated Integrated Pest Management in Europe (C-IPM)

Framework: FP7 — Cooperation
Programme: Food, Agriculture and Fisheries, and Biotechnology
Destination: Sustainable production and management of biological resources from land, forest, and aquatic environment
Action type: Coordination and support actions
Partnership: C-IPM (ERA-NET)
Countries involved: France,Austria,Belgium,Belgium,Switzerland,Czechia,Germany,Germany,Denmark,Estonia,Spain,Finland,Hungary,Ireland,Italy,Lithuania,Netherlands,Netherlands,Norway,Poland,Poland,Poland,Sweden,Türkiye,United Kingdom,Netherlands,Portugal
Call:  (FP7-ERANET-2013-RTD, 2013)
Start date: 2014-01-01
End date: 2016-12-31
Duration (months): 36.0
Total project cost (EUR): 2644343.0
EU funding (EUR): 1998215.0
Participants: 36
Project status: CLOSED

Europe faces the challenge of responding to the mandatory implementation of the principles of Integrated Pest Management (IPM) as called for by Directive 2009/128/EC on the sustainable use of pesticides. Most European countries are investing in research and extension to face this challenge, reduce reliance on pesticides, and reduce risks associated with their use. Added value and synergies can be created by coordinating such national research and extension efforts and by pooling existing resources. To this end, C-IPM will create a forum for exchange and identification of IPM research and development priorities, provide recommendations on national and European research, connect existing initiatives, and coordinate joint transnational research calls. With stakeholders and researchers, C-IPM will position IPM in the future European innovation landscape. It will provide an overall picture of ongoing and desired R&D efforts and of the resources available for IPM implementation. It will propose a common research agenda on IPM and on sustainable solutions in the context of minor uses. It will rapidly generate European-level added value by sharing outputs of ongoing national and regional research, and by disseminating R&D methods, experience and expertise. It will create knowledge hubs by linking R&D resources in the field of IPM and minor uses. It will develop and implement joint transnational calls. A website, newsletter and final workshop will ensure that C-IPM disseminates widely. To achieve lasting impact, C-IPM will plan its continued activity beyond the funded period. C-IPM realises that innovation and sustainability in crop protection can only come about if funders, researchers and farm advisers are closely associated, if multiple sectors are taken into account, and if all available control tactics and strategies are integrated. This approach is key to enriching the suite of IPM techniques and ensuring a high level of implementation of IPM among European farmers.

Keywords: crop protection,ipm,minor uses,pesticides,transnational calls,synergies,research coordination,farm advisory services,forum,knowledge hub,sustainability.
Structure, maturation and cell entry mechanisms of ranavirus virions (STRURANA)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: Czechia
Call:  (FP7-PEOPLE-2013-CIG, 2013)
Start date: 2013-09-01
End date: 2017-08-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

The long-term goal of this proposal is to understand the molecular mechanisms of the replication cycle of nucleocytoplasmic large DNA viruses that attracted attention after the discovery of the giant Mimivirus a decade ago. Here, we focus on ranaviruses from the family Iridoviridae that have caused large economic losses in Europe and Asia and threaten wildlife biodiversity worldwide. The ranavirus disease has therefore been listed by the World Organization for Animal Health. Ranaviruses have a unique replication cycle that leads to two coexisting forms of infectious particles, naked capsids and enveloped virions, each with different mechanisms of cell egress and cell entry. Additionally, the proteinaceous capsid contains an internal membrane that presumably assists to assembly of a large DNA-free icosahedral shell. This shell is subsequently filled by the viral genome and transforms into the mature capsid by a headful packaging mechanism that is also used by some dsDNA bacteriophages. We aim to characterize the structural and mechanistic features of ranavirus assembly, maturation and cell entry by combination of cryo-electron microscopy and tomography with other complementary techniques. The novelty in our plan is application of cryo-FIB micromachining and cryo-electron tomography to visualize the intracellular steps of the ranavirus replication cycle in 3D at native conditions. The three objectives of this research project are to: (i) identify the structural basis of subunit recognition that guides assembly of large icosahedral capsids of type ranaviruses and elucidate the function of the internal membrane in this process, (ii) determine the conformational changes that accompany maturation of ranavirus capsids and regulate the headful packaging of the dsDNA genome, and (iii) ascertain the mechanisms of cell entry by the naked capsids and enveloped ranavirus virions.

Keywords: nucleocytoplasmic large dna viruses,assembly,genome packaging,capsid maturation,cell entry,electron microscopy and tomography,cryo-fib micromachining
Using evolution to uncover the importance of alternative pre mRNA splicing (CONSERVEAS)

Framework: FP7 — People
Programme: Marie-Curie Actions
Theme: Marie Skłodowska-Curie
Destination: Life-long training and career development
Action type: Support for training and career development of researchers (Marie Curie)
Countries involved: United Kingdom
Call:  (FP7-PEOPLE-2013-CIG, 2013)
Start date: 2013-11-01
End date: 2017-10-31
Duration (months): 48.0
Total project cost (EUR): 100000.0
EU funding (EUR): 100000.0
Participants: 1
Project status: CLOSED

A major mystery of the genome age is why complex and simple organisms all have a similar number of genes. My specialism is in ‘Alternative Splicing’ which is the means by which different products can be made from a single gene by differential incorporation of regions of pre-mRNA. Alternative splicing is therefore a mechanism to increase gene complexity in complex organisms like man and in complex tissues like the brain. Alternative splicing has since been shown to be a pervasive mechanism crucial to normal health and development. For two decades labs studied alternative splicing on a gene-by-gene basis. In the last ten years genomewide data has increased the number of known alternative events, and recent developments have found that at least 80% of genes produce alternative mRNAs. The major questions in the field currently concern which of these alternative splices are important, and the problem remains of how to answer this using a huge amount of data. The key innovation of this application is to use an evolutionary approach to identify the important alternative splices using a unique high throughput RT-PCR approach. The proposed project will involve collaboration with biological experts in Newcastle studying brain, muscle and stem cells, with an expert on evolution in France (Dr. Philippe Fort) and with the genomics platform (for which I worked for three years) in Quebec, Canada.

Keywords: alternative splicing,evolution,stem cells,zebrafish,differentiation,development,brain,muscle,genetic disease,biomarkers,cancer