Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
roboTics and Artificial intelligence Living labs improving Operations in PV Scenarios (TALOS)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Digital
Destination: Digital & Emerging Technologies for Competitiveness and Fit for the Green Deal
Action type: Innovation actions
Partnership: AI-DATA-ROBOTICS (co-programmed)
Countries involved: Portugal,Netherlands,Greece,Spain,Luxembourg,Poland,Italy
Call: Increased robotics capabilities demonstrated in key sectors (AI, Data and Robotics Partnership) (IA) (HORIZON-CL4-2022-DIGITAL-EMERGING-02, 2022)
Start date: 2023-10-01
End date: 2026-09-30
Duration (months): 36.0
Total project cost (EUR): 10520860.01
EU funding (EUR): 8769661.5
Participants: 18
Project status: SIGNED

TALOS will develop and demonstrate world-class robotics solutions for different photovoltaic (PV) energy operating scenarios – land-based, floating, and agriPV, promoting innovation in both the energy and agriculture sectors. TALOS will demonstrate the added value of robotics and their potential in reducing greenhouse gas (GHG) emissions (>450ton/year), minimising wasted resources (up to 35% water saved), lowering operation and maintenance (O&M) costs (up to 5%), and optimising human-robot and robot-robot collaboration to reduce humans' exposure to risky environments. Dangerous, dull, or dirty tasks will be performed autonomously by the TALOS solutions – such as monitoring, inspection, cleaning, and vegetation management, where robust robotics solutions will be developed for all PV scenarios and demonstrated to show increasing PV plant performance ratio up to 10%, reducing the risk exposure of O&M workers by 90% or the human burden of monitoring crops by 90% in the demonstration scenarios, allowing feasible inspection periods to be 24/7. A multi-robot platform and recommendation system will demonstrate >30 robot-robot interactions, >30 inspections, and human-in-the-loop features and training sessions for end users and workers. Requirements will be co-created with relevant stakeholders and refined for the technology partners within the consortium, as well as for the 9-13 robotics start-ups that will be granted the cascade funding and demonstrated in the test bed scenarios set up by the project.

Keywords: robotics,autonomous,ai,data analytics,oandm,pv,lcoe,agrivoltaics,floating pv,monitoring,predictive maintenance
The Evolution of Knowledge in the Market for Ideas (KnowEvoIAndIdeasMkt)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Economic Sciences
Countries involved: Spain,Switzerland
Call: MSCA Postdoctoral Fellowships 2021 (HORIZON-MSCA-2021-PF-01, 2021)
Start date: 2023-03-01
End date: 2025-02-28
Duration (months): 24.0
Total project cost (EUR): 203891.04
EU funding (EUR): 203891.04
Participants: 2
Project status: CLOSED

The Evolution of Knowledge shapes our policy choices. Researchers decide what to research, with whom to collaborate, and how much to invest into discovery. While researchers enjoy institutionalized or implicit scientific freedom, two categories govern the researcher's decision which question to address and how much effort to exert: (i) prior knowledge and (ii) the market for ideas. Prior knowledge is vital to determine how knowledge evolves. Researchers stand on the shoulders of giants and use conjectures derived from previous discoveries when they address problems. They assess their ex ante prospects on finding an answer by looking at related findings. However, researchers also operate in the market for ideas. Careers depend on how marketable an idea is, how well researchers exploit synergies and complementarities with collaborators, what topics range high on the policy agenda, and what funding opportunities the researcher can access. In sum, how much effort the researcher invests depends crucially on the market for ideas. Our work combines these two aspects and proposes a flexible model to predict the researcher's choice and determine the evolution of knowledge over time. The model is set up with the data in mind to be able to derive meaningful counterfactuals. We can derive implications for designing the market for ideas, e.g., through adapting the funding architecture. We address questions such as: When should funding focus on cost reductions (e.g., grants), when on rewards (e.g., prizes)? When should we push for "moonshot discoveries" when for incremental research? Should researchers collaborate with experts on similar topics reducing coordination efforts, or with more distant ones exploiting complementarities? Should we let researchers compete on the same topic increasing the probability of finding a solution, or should we urge researchers to differentiate, increasing the number of questions covered?

Keywords: knowledge,innovation,null results,research funding,innovation dynamics
Impacts of ocean oxygen loss on zooplankton behavior and the carbon cycle (O2ZOOM)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Environment and Geosciences
Countries involved: Norway
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-09-01
End date: 2028-08-31
Duration (months): 24.0
Total project cost (EUR): 267418.56
EU funding (EUR): 267418.56
Participants: 1
Project status: SIGNED

The oceans are losing oxygen due to climate change. Among the largest impacts of oxygen loss may be in altering the behavior of zooplankton, the small animals that play a central role in marine ecosystems: as prey, predators, and carbon-flux mediators. The expansion of low-oxygen zones in deep waters may decrease the depth to which zooplankton migrate on a daily and seasonal basis. This change in their migratory behavior would impact the foraging success of their predators as well as reduce the ability of zooplankton to export carbon out of surface waters. O2ZOOM examines how the migratory behavior of krill, a key zooplankton species, is modified by low oxygen in a fjord habitat, and the ramifications for the global carbon pump, through a combination of novel acoustic observations, incubation experiments, and computational models. In O2ZOOM, I will 1) Investigate behavioral changes in krill in response to low oxygen through laboratory incubation experiments 2) Determine the migratory response of krill to low oxygen in a Norwegian fjord using novel acoustic techniques 3) Quantify the effect of low oxygen-induced behavioral changes in krill on carbon export in an individual-based model. O2ZOOM will produce a nuanced picture of the behavioral responses of krill to low oxygen, which would help disentangle the still-unquantified consequences of low oxygen for ecologically important fjord ecosystems, deep-ocean habitats, and, more broadly, the global carbon pump. Furthermore, through O2ZOOM, I will further develop my technical expertise (e.g. in acoustic tracking, advanced modeling, biogeochemistry analysis), expand my scientific network, and increase the impact of my research, steering my career towards answering big-picture questions on the cutting-edge of interdisciplinary ecology.

Keywords: ocean deoxygenation,krill,global carbon pump,marine ecosystem,deep ocean hypoxia,diel vertical migration,biogeochemical cycles,active acoustics,laboratory incubations,modeling
preFabricated deep Renovation with a modulAr Intelligent fraMe driven by autOmated and stReamlined worKflows​ (FRAIMwork)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Climate, Energy and Mobility
Theme: Energy
Destination: Efficient, sustainable and inclusive energy use
Action type: Innovation actions
Partnership: B4P (co-programmed)
Countries involved: Belgium,Netherlands,France,Italy,Germany,Switzerland
Call: Industrialisation of sustainable and circular deep renovation workflows (Built4People Partnership) (HORIZON-CL5-2024-D4-02, 2024)
Start date: 2025-10-01
End date: 2029-09-30
Duration (months): 48.0
Total project cost (EUR): 9923520.65
EU funding (EUR): 7920765.37
Participants: 17
Project status: SIGNED

FRAIMwork enhances renovation rates for small housing units through a unique, cost-effective prefabrication approach, specifically designed for small-scale, non-serial renovations. This method notably reduces renovation costs by 25% and achieves significant time savings. Effective prefabrication for non-serial small- to medium-rise renovations requires practical workflows tailored to all stakeholders. The involvement of different users and manufacturers from the project's beginning underscores a "market-pull approach. FRAIMwork proposes the following innovations: • Developing a BIM-based digital backbone that adds value throughout the entire renovation process, integrating multi-objective optimization to balance economic, environmental, and comfort parameters. • Designing a building envelope renovation concept using circular prefabricated elements that act as carbon sinks, allowing easy installation by small local contractors with simple construction and non-sequential demounting and remounting. • Creating a visually guided installation system utilizing augmented reality and/or façade projections for installation guidance and process feedback. • Implementing a robotic system for the automatic placement of anchors, frames, and prefabricated elements. • Developing a scalable and modular on-site installation approach that combines plug-and-play boxes, decentralized envelope components, and ready-to-assemble boxes for techniques requiring on-site assembly. • Establishing realistic and innovative business models to enhance the scalability of prefabricated renovations and leverage energy communities within renovation projects. A multidisciplinary consortium, including expert centres, academic/research institutions, and industry partners, will ensure the project's successful implementation through a well-structured work plan. This plan is strengthened by demonstrations in Belgium (BE), France (FR), and Germany (DE).

Keywords: renovation,local contractors,individual buildings,nearly zero emissions
Emergent linguistic norms and translated religious prose in eighteenth-century Manx (Manx prose)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Social Sciences and Humanities
Countries involved: United Kingdom
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2025-09-01
End date: 2027-08-31
Duration (months): 24.0
Total project cost (EUR): 276187.92
EU funding (EUR): 276187.92
Participants: 1
Project status: SIGNED

Emergent linguistic norms and translated religious prose in eighteenth-century Manx Manx Gaelic, the native Celtic language of the Isle of Man, was a largely unwritten oral language until the development of an English-based orthography for religious use from the seventeenth century, This process culminated in authorized translations of the Anglican Book of Common Prayer (1765) and a complete Bible translation (1772). This late flowering of Manx literature paradoxically came at a time of increasing language shift to English, which was largely complete by the late nineteenth century. The gradual standardization of the Manx written tradition is attested in an extensive, but hitherto largely unstudied, corpus of manuscripts preserved in the Manx Museum in Douglas, including most notably a large corpus of over 600 sermons dating from the end of the seventeenth century until the mid-nineteenth century, and manuscript drafts of around a fifth of the Bible translation. The latter are extensively annotated by the editors and offer a rich insight into processes of textual interpretation and translation; orthographic, morphological and terminological standardization; and revision and preparation for publication. There is also an extensive body of correspondence between the Manx clergy and an international network of intellectuals and ecclesiastical patrons. This project will build on previous work on the orthographical development of Manx in the sermon corpus, to examine wider processes of linguistic standardization and translation in eighteenth-century Manx, with a particular focus on the Bible translation project completed between the 1720s and 1770s. The project will place these processes in the wider sociohistorical and intellectual context of the eighteenth-century in the Isle of Man and further afield, as well as comparing processes of standardization and translation in Manx with those of other linguistic contexts, especially those of other Celtic languages.

Keywords: gaelic celtic studies historical sociolinguistics language history preaching early modern sermons bible translation palaeography corpus linguistics language variation and change isle of man
Food quality control by RNA profiling (foodRNA) (foodRNA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Sweden
Call: ERC PROOF OF CONCEPT GRANTS (ERC-2024-POC, 2024)
Start date: 2025-06-01
End date: 2026-11-30
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: SIGNED

The field of food quality control is important to all consumers - ensuring food safety and detecting food substitutions and fraud. Next-generation sequencing has the potential to revolutionize the field, but practical solutions are lagging behind. State-of-the-art DNA-based tests yield limited information beyond what animal, plant and bacterial species constitute a given food product - and in some cases performing that task sub-optimally. Profiling RNA in food products can potentially yield important novel information that DNA-based tests cannot - including expression information that can be used to ensure food safety and quality and detect food fraud. With a focus on plant-based food products, we will develop, optimize and set up tests that will be substantially cheaper and more sensitive than the state-of-the-art, allowing upscaling in food quality control. We will provide our product as a service to national food control agencies (which we already collaborate with) and also to high-end food producers as an accreditation service. We foresee that as consumer awareness increases, the demand for these tests will increase exponentially in the future.
WOOD and STOne Conservation by innovative multifunctional nanocomposites based on sustainable matrices (WOODSTOC)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Postdoctoral Fellowships
Action type: Marie Skłodowska-Curie actions
Panel: Information Science and Engineering
Countries involved: Italy,Norway
Call: MSCA Postdoctoral Fellowships 2024 (HORIZON-MSCA-2024-PF-01, 2024)
Start date: 2026-02-01
End date: 2028-01-31
Duration (months): 24.0
Total project cost (EUR): 209483.28
EU funding (EUR): 209483.28
Participants: 2
Project status: SIGNED

Cultural heritage (CH) is highly valued by 84% of European citizens as it reflects both national and European identities, contributing significantly to the economy through tourism, cultural and preservation activities. However, stone and wood objects of CH value can suffer from severe deterioration, mostly decohesion and biodeterioration, which are predicted to be worsened by climate change. Currently, available methods often fail to meet the requirements that conservation treatments must fulfil. To address this, WOODSTOC will develop novel nanocomposites that, for the first time, simultaneously strengthen both stone and wood objects while offering antimicrobial protection in a manner that is both compatible with the materials and highly durable. This will be achieved by combining three types of nanoparticles (ZnO, Ag2O, carbon quantum dots), having different colours and antimicrobial abilities, with two types of matrices (hydroxyapatite formed in situ for stone, hydroxypropyl cellulose for wood) which are more sustainable compared to existing alternatives. The project outcomes will enable a more efficient and sustainable preservation of our cultural heritage, thus significantly contributing to UN’s Sustainable Development Goals (SDGs), particularly SDG 11.4 (“Strengthen efforts to protect and safeguard the world’s cultural and natural heritage”). The development of new composites in Europe, as opposed to competing countries where research is ongoing, will also increase European competitiveness. Most importantly, WOODSTOC will give the Postdoctoral Researcher the opportunity to deepen and diversify her scientific knowledge and technical competence, thanks to the research and training provided by the two host institutions (one university and one museum, having complementary fields of expertise, mind-sets and facilities), thus achieving the PR’s career development goal to fortify her independence as a researcher.

Keywords: wood,stone,conservation,nanoparticles,antimicrobial ability,sustainable materials
Targeting NLRP3-mediated inflammation with novel chemotypes (PyroScreen)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Proof of concept grants
Action type: ERC actions
Countries involved: Belgium
Call: ERC PROOF OF CONCEPT GRANTS2 (ERC-2022-POC2, 2022)
Start date: 2022-10-01
End date: 2024-03-31
Duration (months): 18.0
Total project cost (EUR): 150000.0
EU funding (EUR): 150000.0
Participants: 1
Project status: CLOSED

Inflammasomes play a vital role in in protecting humans against pathogenic microorganisms, harmful substances and cell changes that could result in illness. The NLRP3 inflammasome in particular attracts considerable interest because aberrant NLRP3 activation is a key pathogenic mechanism in many chronic inflammatory diseases. Moreover, gain-of-function mutations in NLRP3 causes a periodic fever syndrome named cryopyrin-associated periodic syndrome (CAPS). MCC950/CRID3-based sulfonylurea compounds are currently the only reported class of inhibitors that selectively target NLRP3 with nM potency. We and others recently showed that members of this sulfonylurea class inhibitors directly target the central NACHT domain of NLRP3, and several companies have recently progressed MCC950/CRID3-derived NLRP3 inhibitors to human studies. However, there is an urgent need to expand the pipeline of NLRP3-targeted therapeutics with NLRP3-inhibitors of novel chemotypes. Based on exciting preliminary data, we aim to identify novel NLRP3 inflammasome inhibitors and perform an in-depth functional analysis of their activity, selectivity and molecular mechanism of action. Furthermore, we will define the market potential and explore the best strategy towards clinical development with partner organizations. In conclusion, the project will help to expand the pipeline of NLRP3-targeted therapeutics with new NLRP3-inhibitors. If successful, the project may meaningfully impact on the lives of many patients that suffer from NLRP3-mediated diseases in Europe and across the globe.
A CEllulaR immunoTherapy virtuAl twin for personalIsed cancer treatmeNT (CERTAINTY)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Health
Theme: Health
Destination: Unlocking the full potential of new tools, technologies and digital solutions for a healthy society
Action type: Research and Innovation actions
Countries involved: Germany,Belgium,Czechia,Luxembourg,France,Netherlands,United States,Switzerland
Call: Integrated, multi-scale computational models of patient patho-physiology (‘virtual twins’) for personalised disease management (HORIZON-HLTH-2023-TOOL-05, 2023)
Start date: 2023-12-01
End date: 2028-05-31
Duration (months): 54.0
Total project cost (EUR): 10060452.5
EU funding (EUR): 9999252.5
Participants: 17
Project status: SIGNED

This project aims to create a multi-scale patient-specific human virtual twin for patients who are eligible for CAR T cell therapy, which can be extended to cellular immunotherapies in general. The virtual twin will be fully integrated into the ecosystem under the Digital Europe Programme and will be available as a research-use-only prototype in relevant application environments with technology readiness level 6. The virtual twin will support decision-making throughout the patient's journey, from diagnosis to pre-treatments, cellular immunotherapy, and late patient monitoring. This will enable patients and health experts to identify the most effective course of therapy. The virtual twin for cellular immunotherapies will take multi-scale modelling to the next level by providing methodological concepts for integrating "living drugs" such as CAR T cells into the human virtual twin ecosystem. To achieve this goal, the project builds on existing data models for hematological malignancies and multiple myeloma (MM) to create a virtual twin for CAR T cell therapy for MM patients. The implementation process follows software development principles for software as medical devices, ensuring the exploitation of the research-use-only prototype. Patient's, SSH, gender differences, and other stakeholders' perspectives are fully integrated into the design, specification, and implementation process. Throughout the implementation process, a modular software architecture and extensible ontologies/terminologies are utilized, making the reference model easily transferable to other indications that can be treated with CAR T cell therapy or other cellular immunotherapies. Overall, the CERTAINTY virtual twin will provide decision support for patients and health experts, improving the effectiveness of cellular immunotherapies and advancing precision medicine.

Keywords: car t,virtual twin,single cell,multiple myeloma