Data-Gouv-ML/pcri-informations-sur-les-projets-laureats huggingface dataset:
4Sir2 Smoothy: Building a Healthy Drink Ecosystem to Prevent Childhood Obesity (4Sir2)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Research and Innovation actions
Countries involved: Poland,Latvia,Portugal,Germany,Belgium,Moldova, Republic of,United Kingdom,Italy,Greece
Call: New healthy and sustainable food products and processes (HORIZON-CL6-2024-FARM2FORK-01, 2024)
Start date: 2025-09-01
End date: 2030-02-28
Duration (months): 54.0
Total project cost (EUR): 4999555.0
EU funding (EUR): 4999555.0
Participants: 16
Project status: SIGNED

The project aims at creating a functional beverage tailored for obese children, utilizing either grape or apple juice as its base. This beverage will be enriched with unique compounds derived from the by-products of red grape processing, namely resveratrol and polyphenols. These compounds have demonstrated the capacity to activate anti-obesity genes, specifically sirtuins, through their expression.The primary goal of the 4Sir2 project is to bring to bring revolutionary technological advancements in both grape cultivation and processing industries, as well as the production of health-oriented beverages: 4Sir2 will innovate and create a novel functional beverage 4Sir2 smoothie, aimed at preventing child obesity and will establish sustainable processes within the grape processing industries across the European Union and beyond. The new functional 4Sir2 smoothie will activate the expression of genes responsible for sirtuin proteins, thereby mitigating obesity. Specifically tailored for obese children, this project focuses on providing essential nutritional interventions. Hence, the aim is twin: firstly, to prevent the entrenchment of obesity and foster healthy dietary habits from an early age through the consumption of juices and nutritious foods; secondly, by targeting children, the project aspires to influence the eating habits of entire families. The 4Sir2 project fulfils all the requirements outlined in the Work programme. It stands out as a healthier alternative compared to currently available functional drinks, boasting a formulation centred on natural ingredients that are not only delicious but also affordable and undergo minimal processing. Moreover, the production processes developed within the 4Sir2 project are designed with a keen focus on minimising environmental and climate impact. Focusing attention on grape pomace management and usage as the source of sirtuin activators, the project extends its positive influence to society.

Keywords: waste utilization,obesity prevention,resveratrol,sirtuins,new functional drink,gene expression,nutritional interventions,preventing obesity perpetuation,minimising environmental impact
MANUFACTURING AS A SERVICE TO INCREASE RESILIENCE IN VALUE NETWORKS (MAASive)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Digital, Industry and Space
Theme: Industry
Destination: Climate neutral, Circular and Digitised Production
Action type: Research and Innovation actions
Partnership: Made in Europe (co-programmed)
Countries involved: Denmark,Italy,Germany,France,Türkiye,Romania
Call: Achieving resiliency in value networks through modelling and Manufacturing as a Service (Made in Europe Partnership) (RIA) (HORIZON-CL4-2023-TWIN-TRANSITION-01, 2023)
Start date: 2024-01-01
End date: 2026-12-31
Duration (months): 36.0
Total project cost (EUR): 5711992.5
EU funding (EUR): 5711992.5
Participants: 12
Project status: SIGNED

MAASiveTraditional value chains are facing challenges due to the fast-moving markets, customer demands, and unpredictable manufacturing and logistics. To address these challenges, Manufacturing as a Service (MaaS) is introduced as a concept that utilizes existing resources in a value network by connecting manufacturers to service providers on demand through a connected network. The MAASive project aims to develop models of value networks that enable companies to recover from unforeseen external events by connecting to new services and reconfiguring value networks utilizing internal and external manufacturing services. MAASive will provide a toolkit for industry, which will consist of a blend of existing methods and technology applied in the MaaS context, and new models and technology developed as part of the project. Four distinct aspects are addressed in the MAASive project to increase resilience in value networks: network building, impact assessment, reorchestration of networks, and value network operation. The overall aim of MAASive is to increase value network resilience by enabling manufacturers to rapidly respond to unforeseen external events or sudden changes in supply or demand, utilizing manufacturing as a service. MAASive uses an iterative approach to develop technical solutions and identify potential technology risks early on. The project is focused on creating a toolkit from a human-centered perspective and involving professionals and workers in requirement and scenario definition. The iterative approach follows three loops focusing on 1) model foundations, 2) impact simulation and scenarios, and 3) network orchestration and operation. The results of MAASive will be developed in two use case demonstrators. The results of MAASive will contribute to companies being more resilient towards external, unforeseen events, by being able to utilize services in a value network better and faster, while also increasing utilization of network resources.

Keywords: manufacturing as a service,resilience,value networks,model based production,value network orchestration,manufacturing ecosystems,industrial production
Photoinhibition: Nature of the process and Influence on primary productivity Across Scales (PHOTONICS)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Starting grants
Action type: ERC actions
Panel: Molecules of Life: B iological  Mechanisms , Structures  and Functions
Panel description: For all organisms : Molecular biology , biochemistry, structural biology, molecular biophysics , synthetic and chemical biology, drug design, innovative methods and modelling
Countries involved: France
Call: ERC STARTING GRANTS (ERC-2023-STG, 2023)
Start date: 2024-09-01
End date: 2029-08-31
Duration (months): 60.0
Total project cost (EUR): 1498315.0
EU funding (EUR): 1498315.0
Participants: 1
Project status: SIGNED

Photosynthetic microbes contribute over 50% of carbon fixation on Earth. Inhabiting extremely diverse environments, they always have to cope with a friend that is simultaneously their enemy: sunlight. Photon energy is necessary for photosynthesis, but it continuously damages the photosynthetic apparatus, primarily the first enzyme in oxygenic photosynthesis – Photosystem II (PSII) – in the process of photoinhibition. Upon photodamage, PSII becomes irreversibly inactivated, unable to do electron transfer, and requires costly repair involving protein translation. Photoinhibition represents a major limiting factor to terrestrial and aquatic photosynthesis. Despite decades of research on PSII and photoinhibition, many key aspects of photoinhibition remain unresolved, among them: -the site within the PSII complex where the photoinhibitory damage takes place, as well as its molecular nature -partitioning of the known different types of damage, dependent on the environment and conditions -the role of the mysterious haem b559, conserved in phototrophs close to PSII reaction centre and transferring electrons, long speculated to play a role in photoprotection but with no convincing role assigned to date In PHOTONICS, I aim to focus on these issues to provide a thorough description of photoinhibition and photoprotection strategies in photosynthetic microbes. I will use a combination of novel in vivo methods, taking advantage of the most recent developments in time-resolved fluorescence- and absorption spectroscopies. These will be combined with genetics and state-of-the-art structural biology. It is the integrative nature of PHOTONICS, bridging different scales of complexity in a hypothesis-driven manner, that will allow to finally resolve the critical missing pieces of PSII function and damage. Finally, it will provide a methodological blueprint for assessment of photoinhibition in situ, and aid modelling of photosynthetic productivity under fluctuating conditions.

Keywords: photosynthesis,photophysics,time resolved spectroscopy
Extended Network of CBRN Training Centres for Innovation (eNOVATION)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Civil Security for Society
Theme: Civil Security for Society
Destination: Disaster-Resilient Society for Europe
Action type: Innovation actions
Countries involved: Belgium,Italy,Greece,Germany,Slovakia,Sweden,Spain,Czechia,Poland,United Kingdom,Türkiye,Ukraine,Georgia,Morocco,Armenia,Uzbekistan
Call: Internationally coordinated networking of training centres for the validation and testing of CBRN-E tools and technologies in case of incidents, with consideration of human factors (HORIZON-CL3-2023-DRS-01, 2023)
Start date: 2024-09-01
End date: 2027-08-31
Duration (months): 36.0
Total project cost (EUR): 4498746.25
EU funding (EUR): 4498744.0
Participants: 23
Project status: SIGNED

In response to evolving risk landscapes, governments and international organizations have adopted comprehensive programs to enhance preparedness and response capabilities. Building on eNOTICE and eNOTICE-2, eNOVATION addresses the increasing threat of Chemical and Biological threats including Toxin (CB/T) incidents, whether natural, intentional, or accidental, as well as the risk posed by "Do-It-Yourself" technologies. eNOVATION aims to expand and strengthen the network of CBRN training centres, including the CBRN Centre of Excellence in regions like the Africa Atlantic Façade (Rabat, Morocco), Central Asia (Tashkent, Uzbekistan), and South East and East Europe (Tbilisi, Georgia, and CBRN CoE partner in Armenia). The project's main goal is to upgrade the training (Trg) framework for first responders in managing CB/T incidents and evaluating on-site emerging tools and technologies for detection, identification, monitoring, and decontamination. eNOVATION introduces new Trg methods that integrate upgraded courses, AI-supported technologies, enhancing automation and user-friendliness, as well as augmented and extended reality (AR/XR). The Network will guide pre-normative research for technologies and Trg methodologies. Altogether, technologies evaluated on-site are sourced from eNOVATION partners, ENCIRCLE, and eNOVATION supplier platforms. The project outcomes aim to integrate human factors and societal considerations into emergency response, including international Assistance to vulnerable and disabled people, assessment of stockpile mobilisation for hospitals in CBRN CoE partner countries during CB/T crises. The web application “eNOVATION Cube” is central to the project: integrating an ontology-driven matchmaking process to serve as a reference and benchmark for training FR and for technologies labelled after success evaluation on-site. This will have a direct impact on research, operational, and policy processes while supporting the sustainability of the netw

Keywords: network of cbrn training centres eu and outside eu cbrn standards for technologies and methodology of cbrn trainings
NATURAL BIO-MASS AND MICROBIAL BIO-CONTROL AGENT SOLUTIONS FOR THE REPLACEMENT OF CONTENTIOUS INPUTS IN ORGANIC FARMING (BIO2)

Framework: Horizon Europe — Global Challenges and European Industrial Competitiveness
Programme: Food, Bioeconomy Natural Resources, Agriculture and Environment
Theme: Bio-Environment
Destination: Fair, healthy and environmentally-friendly food systems from primary production to consumption
Action type: Innovation actions
Countries involved: Italy,Norway,Latvia,Spain,Austria,Bulgaria,Germany,Sweden
Call: Increasing the availability and use of non-contentious inputs in organic farming (HORIZON-CL6-2024-FARM2FORK-02, 2024)
Start date: 2025-05-01
End date: 2029-04-30
Duration (months): 48.0
Total project cost (EUR): 6375198.69
EU funding (EUR): 5998209.35
Participants: 20
Project status: SIGNED

BIO2 aims to transform organic farming (OF) by replacing contentious inputs with sustainable alternatives through innovative R&D. The main innovations are: (i) combining marine materials (fish discards and seaweed byproducts), microorganisms, and recycled sewage nutrients to create fertilizers tailored for OF; (ii) encapsulating biocontrol agents (e.g., yeast and bacteria) in biogenic materials to enhance their efficacy in protecting crops from diseases; (iii) developing processes for manufacturing microalgal-based agricultural fungicides; and (iv) producing immunostimulants and bark extracts with antiparasitic properties. To facilitate the integration of BIO2 solutions into OF and make them viable for farmers, we will scale up production processes and provide sufficient materials for testing in agronomic and animal trials from the project's early stages. The efficacy of these products will be studied and compared with contentious inputs, such as copper- and sulfur-based fungicides, mineral oils, manure from conventional farming, and synthetic antibiotics. BIO2 will prioritize sustainability assessments and actively engage stakeholders (industries, the OF sector, farmers transitioning to OF, and consumers) to develop products that are both environmentally friendly and accepted by end users. Potential barriers, such as raw material quality and availability, product costs, farmers’ acceptance, and regulatory challenges, will be addressed by diversifying material sources and involving key actors. By leveraging advanced technologies and interdisciplinary collaboration, BIO2 will deliver tangible outcomes, including the industrial production of at least 1 biocontrol agent, 2 fertilizers, and 1 antiparasitic treatment. Through its comprehensive approach, BIO2 not only addresses current limitations in OF but also contributes to broader sustainability goals by reducing environmental impacts and promoting a circular economy.

Keywords: fertilization calcium phosphates circularity food byproducts
Photovoltaics Reliability Operations and Maintenance Innovative Solutions for Energy Alliance (PROMISE)

Framework: Horizon Europe — Widening Participation and Strengthening the European Research Area
Programme: Widening participation and spreading excellence
Theme: Improved access to Excellence
Destination: Improved access to Excellence
Action type: Coordination and support actions
Countries involved: Malta,Austria,France,Spain,Germany,Belgium
Call: Twinning (HORIZON-WIDERA-2021-ACCESS-03, 2021)
Start date: 2022-10-01
End date: 2025-10-31
Duration (months): 37.0
Total project cost (EUR): 1500105.93
EU funding (EUR): 1500000.0
Participants: 7
Project status: SIGNED

PROMISE aims to create an alliance of photovoltaic excellence through scientific, engineering and research performance within the Maltese research community reliability of existing and emerging module technologies and systems, including the digitalisation aspects for prediction and optimisation algorithms for innovative solutions to support the energy transition. The Maltese research community, led by the Foundation for Innovation and Research – Malta (FiR) and supported by local technology innovator PIXAM Ltd. will stimulate scientific excellence and sustained collaborations with four world-leading research institutions AIT (Austria), CENER (Spain), CEA (France), and BI Becquerel Institute (Belgium), and Anhalt University of Applied Sciences (Germany) as the leading EU academic applied practice partner. In particular, PROMISE will perform two programmes in research and knowledge considering gender balance, early career researchers and sustainable development goals. The research framework includes a bottom-up approach for a Malta-based research platform on PV reliability, including infrastructure, data collection, analysis and modelling/verification through module test rig, satellite and drone vision technologies and an in-field database of solar module manufacturers. The knowledge gain and transfer framework includes capacity building activities, including a series of workshops, winter/summer schools, training programmes, internships, meetings, mentoring, and research management and administration upskilling. The PROMISE results, lessons learnt, best practices, and success stories will feed a scalability opportunity, extending the research platform to a nationwide/regional landscape while also generating concrete research capacity for a more enabling environment for research in PV reliability in Malta as a solar country and regional energy hub.

Keywords: photovoltaics,reliability,performance
Physics and Applications of Negative IONS (PANIONS)

Framework: Horizon Europe — Excellent Science
Programme: Marie Skłodowska-Curie Actions (MSCA)
Theme: Marie Skłodowska-Curie
Destination: Doctoral Networks
Action type: Marie Skłodowska-Curie actions
Panel: Physics
Countries involved: Sweden,Netherlands,Germany,Austria,Israel,Slovakia,Switzerland,United Kingdom,United States,Canada,Finland
Call: MSCA Doctoral Networks 2024 (HORIZON-MSCA-2024-DN-01, 2024)
Start date: 2026-01-01
End date: 2029-12-31
Duration (months): 48.0
Total project cost (EUR): 4363215.12
EU funding (EUR): 4363215.12
Participants: 27
Project status: SIGNED

The structures of atoms and positive ions are well known for more than 100 years. In contrast, negative ions are less well understood as they are much more difficult to investigate and detect. This is because their binding energies are very small, and only a handful of them have excited states with the same parity as the ground state. Hence, traditional spectroscopic methods cannot be applied to most negative ions, leaving them poorly characterised despite their importance for many scientific and technological applications. The PANIONS Doctoral Network aims at substantially advancing our understanding of negative ions beyond the state-of-the-art from atomic to cosmic scales and bridging the gap between fundamental science and applications. Our interdisciplinary approach will be implemented by 14 DCs employing advanced theoretical models and sophisticated experimental methods. Key properties of atomic and molecular anions and their interactions with other particles will be investigated to fully describe negative ions in a variety of environments, from vacuum to plasmas, interstellar clouds and planetary surfaces. This ambitious research and training programme is only possible through a collaborative effort of a pan-European consortium of scientific excellence with access to a range of experimental facilities and the involvement of innovative companies with complementary expertise. Exploiting the full potential of the scientific discoveries requires a structured training programme to equip the next generation of experts in negative ions with advanced scientific and transferable skills. Acquiring a comprehensive skillset that is relevant to essentially any field of advanced science and technology, will prepare the recruited DCs for future careers in academia and industry. In the long-term, PANIONS will unleash various applications of negative ions with a profound impact on how we generate energy, investigate our universe, and on medical applications.

Keywords: negative ions,photodetachment,electron correlation,ion traps,laser spectroscopy,fusion,accelerator mass spectrometry,ion sources,storage ring,mutual neutralisation,interstellar medium,moon
Linguistic Texts of Roman Antiquity. Collecting fragments, sources and lexicon in a digital environment (LiTeRA)

Framework: Horizon Europe — Excellent Science
Programme: European Research Council (ERC)
Theme: European research council
Destination: Advanced grants
Action type: ERC actions
Panel: Texts and Concepts
Panel description: Literary studies , literature,  philosophy
Countries involved: France
Call: ERC ADVANCED GRANTS (ERC-2023-ADG, 2023)
Start date: 2025-01-01
End date: 2029-12-31
Duration (months): 60.0
Total project cost (EUR): 2497750.0
EU funding (EUR): 2497750.0
Participants: 1
Project status: SIGNED

All modern histories of Western linguistics start with its Greek origins (5th - 3rd cent. BC) and then, after mentioning the Latin Republican polymath Varro (1st cent. BC), jump several centuries to explore only some prominent, late figures (4th - 6th cent. AD). The aim of the LiTeRA project is to provide a holistic perspective on the birth and configuration of Roman linguistic science (2nd cent. BC - 3rd cent. AD), an essential moment in the evolution of Western culture. Although we have inherited valuable sources from the late Latin grammatical tradition, this project will shed light on the overlooked works of the preceding Republican and early imperial periods, a vast body of texts, which have not survived in their entirety, but have been excerpted and quoted in late normative handbooks, commentaries, and lexica. LiTeRA’s three interrelated objectives illuminate how the history of ancient Roman linguistic thought can be substantially rewritten by mobilizing: - A heuristic step: to collect all of the foundational fragmentary texts of Latin grammar, written by a hundred authors and transmitted in the source-texts of late antiquity; - A hermeneutic step: to contextualize the interpretation of the lost texts, extending the sources of Latin grammar to the wider context of ancient Roman scholarship; - A historical step: to reconstruct the evolution of Latin grammatical terminology from its historical roots in the reference corpus of source-texts to its modern conceptualization. LiTeRA’s unique approach to decipher the internal correlations between these related corpora, which are not at all mutually exclusive, will necessitate new methodologies that consider their textual polyphony and intricate technical vocabulary. LiTeRA demonstrates that examining these interconnected issues can only be accomplished in a digital environment that guarantees the interoperability of its objects.

Keywords: history of linguistics,ancient grammar,fragmentary texts,linguistic terminology,latin grammarians,ancient scholarship